ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIV0800 good L KOG3084 Replication, recombination and repair NADH pyrophosphatase I of the Nudix family of hydrolases
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIV0800 264970 263819 -384
(384 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YGL067w [L] KOG3084 NADH pyrophosphatase I of the Nudix family o... 363 e-100
SPBC1778.03c [L] KOG3084 NADH pyrophosphatase I of the Nudix fam... 140 4e-33
At5g20070 [L] KOG3084 NADH pyrophosphatase I of the Nudix family... 108 1e-23
Hs13899267_2 [L] KOG3084 NADH pyrophosphatase I of the Nudix fam... 105 9e-23
Hs17470986 [L] KOG3084 NADH pyrophosphatase I of the Nudix famil... 76 7e-14
CE27958 [L] KOG3084 NADH pyrophosphatase I of the Nudix family o... 64 4e-10
>YGL067w [L] KOG3084 NADH pyrophosphatase I of the Nudix family of
hydrolases
Length = 384
Score = 363 bits (931), Expect = e-100
Identities = 187/383 (48%), Positives = 254/383 (65%), Gaps = 14/383 (3%)
Query: 1 MERSVTFFGLETINRVSFLRDDEVFIKQAFEHGSTQFVPFINGAAFATETSDKSGTNLLM 60
M +VTFFG +NRVSFLR + FIK++ H ST F+PFI G A S ++G +L+
Sbjct: 1 MSTAVTFFGQHVLNRVSFLRCSKEFIKKSLNHDSTVFIPFIEGEALI---SPENG-DLVQ 56
Query: 61 LGHQGCPNYSEWPGLLNKIRSVMDTERGWLVESGFTITFLGLMDG-DSSFSYK----EYT 115
L + + ++ ++++T R ESG +TFLGL++G DS+F+++ Y
Sbjct: 57 LSNSVKSYKNILSAIVPLYTTLLNTTRSRSDESGINVTFLGLLEGTDSAFNFEWSNISYK 116
Query: 116 GTPLFAMDLRPASDTLVQKSETKFILDQYEPLGRMQAFNLSNEVASLFSHANMYLDWLRK 175
GTP F +D+R TL +K + + I Y + R F +NE ASL+S MYLDWL K
Sbjct: 117 GTPYFGLDIRVTESTLFKKVDFEPIFS-YPKVTRDHIFKQTNEDASLYSQGKMYLDWLAK 175
Query: 176 FLFCPGCASKVFPVHGGTKLQCGNNDESVKCSVRDAAVSNVCFPRTDPVVIVAIVDRCFS 235
+ FCPGC S +FPV GTKLQC N + +V C+VRDA ++NVCFPRTDP VI+A+ + +S
Sbjct: 176 YKFCPGCGSPLFPVEAGTKLQCSNENRNVYCNVRDARINNVCFPRTDPTVIIALTNSDYS 235
Query: 236 KICLARSRRKHGNAVMYSTIAGFMEPAETVEHACQREIWEETGIKVELNDVDILFTQPWP 295
K CLARS++++G+ V+YSTIAGFMEP+ET+E AC REIWEETGI + ++DI+ +QPWP
Sbjct: 236 KCCLARSKKRYGDFVLYSTIAGFMEPSETIEEACIREIWEETGISCK--NIDIVRSQPWP 293
Query: 296 YPCNLMIGCLGLIDFNGDNEIINLEHDKELLDAQWFEMELVSQAFERYGKAPKGLVNFDD 355
YPC+LMIGCLG++ FN NE+INL HD ELLDAQWF+ + QA ++Y + V F +
Sbjct: 294 YPCSLMIGCLGIVQFNSKNEVINLNHDDELLDAQWFDTTEIIQALDKYAGGYR--VPFKN 351
Query: 356 RITFPGDTAIAHQLIEHAVIKYK 378
I PG T IA QLI H YK
Sbjct: 352 DINLPGSTTIAFQLINHVCENYK 374
>SPBC1778.03c [L] KOG3084 NADH pyrophosphatase I of the Nudix family of
hydrolases
Length = 376
Score = 140 bits (352), Expect = 4e-33
Identities = 110/371 (29%), Positives = 178/371 (47%), Gaps = 33/371 (8%)
Query: 7 FFGLETINRVSFLRDDEVFIKQAFEHGSTQFVPFINGAAFATETSDKSGTNLLMLGHQGC 66
FF ++NR+SFLR + F+ +AF +T+F+PF + DK L+ L +
Sbjct: 19 FFAGSSLNRLSFLRSNREFLNKAFYDHTTRFLPFCDLNPALLVKDDK----LVTLSYPQI 74
Query: 67 PNYSEWPGLLNKIRSVMDTERGWLVESGFTITFLGLMDGDSSFSYKEYTGTPLFAMDLRP 126
Y + + + + ER ES + ++G + + + ++ +FA+D+
Sbjct: 75 SKYFTFSPFEHTDKQI--AERFSKGESLPVLVYMG--NEERNGPTDNWSQHNVFAIDITG 130
Query: 127 ASDTLVQKSETKFILDQYEPLGRMQAFNLSNEVASLFSHANMYLDWLRKFLFCPGCASKV 186
+ + + Q + LS + + A LDW+ ++ FCPGC +
Sbjct: 131 IDELQQSIRDNGGTFVNLRSIFTEQ-YQLSASDSGACAFARSILDWISRYRFCPGCGKRN 189
Query: 187 FPVHGGTKLQCGN---NDESVKCSVRDAAVSNVCFPRTDPVVIVAIVDRCFSKICLARSR 243
P GGTKL C + ND+S C + ++N +PRTDP VI+ I+ I L R+
Sbjct: 190 IPTMGGTKLVCSDVLLNDDS-NCPSK-KGINNYQYPRTDPCVIMVILSHDMQHILLGRAL 247
Query: 244 RKHGNAVMYSTIAGFMEPAETVEHACQREIWEETGIKVELNDVDILFTQPWPYPCNLMIG 303
R +Y+ +AGF+EP E++E A RE +EE+G+ VE V +QPWP+P +LM+
Sbjct: 248 RHPKG--LYACLAGFLEPGESLEEAVVRETYEESGVDVE--KVLYYASQPWPFPQSLMLA 303
Query: 304 CLGLIDFNGDNEIINLEHDKELLDAQWFEMELVSQAFE---RYGKAPKGLVNFDDRITFP 360
C G+ N I + D EL D ++F E V ++ E + G AP I FP
Sbjct: 304 CFGIARKNAK---IQRDKDLELEDVRFFSREEVLRSLEWDAKDGPAP---------ILFP 351
Query: 361 GDTAIAHQLIE 371
+IA LI+
Sbjct: 352 PKLSIARNLIQ 362
>At5g20070 [L] KOG3084 NADH pyrophosphatase I of the Nudix family of
hydrolases
Length = 438
Score = 108 bits (270), Expect = 1e-23
Identities = 74/198 (37%), Positives = 100/198 (50%), Gaps = 33/198 (16%)
Query: 161 SLFSHANMYLDWLRKFLFCPGCASKVFPVHGGTKLQCGNNDESVKCSVRDAAVSNVCFPR 220
++ +A L+W FC C SK FP G + QC +DE+ + V +PR
Sbjct: 194 AIAGNARALLEWHNVSQFCGSCGSKTFPKEAGRRKQC--SDETCRKRV---------YPR 242
Query: 221 TDPVVIVAIVDRCFSKICLARSRRKHGNAVMYSTIAGFMEPAETVEHACQREIWEETGIK 280
DPVVI+ ++DR + L+R R M+S +AGF+EP E++E A +RE WEETGI
Sbjct: 243 VDPVVIMLVIDRENDRALLSRQSRYVPR--MWSCLAGFIEPGESLEEAVRRETWEETGI- 299
Query: 281 VELNDVDILFTQPWP-----YPCNLMIGCLGL---IDFNGDNEIINLEHDKELLDAQWFE 332
E+ DV +QPWP PC LM+G +D N D E EL DAQW
Sbjct: 300 -EVGDVVYHSSQPWPVGPSSMPCQLMLGFFAFAKTLDINVDKE--------ELEDAQWHS 350
Query: 333 MELVSQAF--ERYGKAPK 348
E V +A Y KA +
Sbjct: 351 REEVKKALAVAEYRKAQR 368
>Hs13899267_2 [L] KOG3084 NADH pyrophosphatase I of the Nudix family of
hydrolases
Length = 183
Score = 105 bits (263), Expect = 9e-23
Identities = 74/199 (37%), Positives = 101/199 (50%), Gaps = 25/199 (12%)
Query: 175 KFLFCPGCASKVFPVHGGTKLQCGNNDESVKCSVRDAAVSNVCFPRTDPVVIVAIVDRCF 234
++ FCP C + GG K C D C + V N +PR DPVVI+ ++
Sbjct: 1 RYKFCPTCGNATKIEEGGYKRLCLKED----CPSLNG-VHNTSYPRVDPVVIMQVIHPDG 55
Query: 235 SKICLARSRRKHGNAVMYSTIAGFMEPAETVEHACQREIWEETGIKVELNDVDILFTQPW 294
+K L R +R M++ +AGF+EP ET+E A +RE+ EE+G+KV V + QPW
Sbjct: 56 TKCLLGRQKRFPPG--MFTCLAGFIEPGETIEDAVRREVEEESGVKV--GHVQYVACQPW 111
Query: 295 PYPCNLMIGCLGLIDFNGDNEIINLEHDK-ELLDAQWFEMELVSQAFERYGKAPKGLVNF 353
P P +LMIGCL L ++ DK E+ DA+WF E V + GK V
Sbjct: 112 PMPSSLMIGCLALA------VSTEIKVDKNEIEDARWFTREQVLDVLTK-GKQQAFFV-- 162
Query: 354 DDRITFPGDTAIAHQLIEH 372
P AIAHQLI+H
Sbjct: 163 ------PPSRAIAHQLIKH 175
>Hs17470986 [L] KOG3084 NADH pyrophosphatase I of the Nudix family of
hydrolases
Length = 352
Score = 76.3 bits (186), Expect = 7e-14
Identities = 73/233 (31%), Positives = 103/233 (43%), Gaps = 32/233 (13%)
Query: 149 RMQAFNLSNEVASLFSHANMYLDWLRKFLFCPGCASKVFPVHGGTKLQCGNNDESVKCSV 208
R F L+ ASL S A L W FC G+K C +N+
Sbjct: 139 RKALFQLNARDASLLSTAQALLRWHDAHQFCSRSGQPTKKNVAGSKRVCPSNNI------ 192
Query: 209 RDAAVSNVCFPRTDPVVIVAIVDRCFSKICLARSRRKHGNAVMYSTIAGFMEPAETVEHA 268
+ +P+ PV I + D CL +R+ MYS +AGF + E+VE
Sbjct: 193 -------IYYPQMAPVAITLVSD---GTRCLL-ARQSSFPKGMYSALAGFCDIGESVEET 241
Query: 269 CQREIWEETGIKVELNDVDILFTQPWPYPC-NLMIGCLGLIDFNGDNEI-INLEHDKELL 326
+RE+ EE G++VE + +Q WP+P +LMI C + G EI +NL +EL
Sbjct: 242 IRREVAEEVGLEVE--SLQYYASQHWPFPSGSLMIACHATVK-PGQTEIQVNL---RELE 295
Query: 327 DAQWFEMELVSQAFER---YGKAPKGLVNFDDRITFPGDTAIAHQLIEHAVIK 376
A WF + V+ A +R Y + G F P AI+HQLI+ V K
Sbjct: 296 TAAWFSHDEVATALKRKGPYTQQQNGTFPF----WLPPKLAISHQLIKEWVEK 344
>CE27958 [L] KOG3084 NADH pyrophosphatase I of the Nudix family of
hydrolases
Length = 348
Score = 63.9 bits (154), Expect = 4e-10
Identities = 78/275 (28%), Positives = 112/275 (40%), Gaps = 42/275 (15%)
Query: 116 GTPLFAMDLRPASDTLVQKSETKFILDQY-EPLG------RMQAFNLSNE-VASLFSHAN 167
GT + A D P D+ + K E +L Q LG RM + E +L +
Sbjct: 89 GTSIDAAD--PPEDSPISKKE---VLKQLGNSLGGRFTDIRMAMLTMREERQRNLLAKFQ 143
Query: 168 MYLDWLRKFLFCPGCASKVFPVHGGTKLQCGNNDESVKCSVRDAAVSNVCFPRTDPVVIV 227
W + CP CA+ L+ ++ +C V +P PV I
Sbjct: 144 SLTKWASIYRRCPKCAAA---------LKMRSSKSGAEC----VTCQRVYYPTFSPVSIT 190
Query: 228 AIVDRCFSKICLARSRRKHGNAVMYSTIAGFMEPAETVEHACQREIWEETGIKVE-LNDV 286
I D L R R G +++ +AGF E++ +REI EE GI+V+ + +
Sbjct: 191 LITDPTNEHALLVRHRGSAGG--VFTAVAGFAHSGESMAECARREIAEEVGIEVDSIRSL 248
Query: 287 DILFTQPWPYP-CNLMIGCLGLIDFNGDNEIINLEHDKELLDAQWFEMELVSQAFERYGK 345
D+ +QPWP P +LMI + + + + EL AQWF V +A
Sbjct: 249 DM--SQPWPMPDSSLMIAHVAVAKIDQKISVC----PDELETAQWFTRHQVKEALTTTLA 302
Query: 346 AP--KGLV-NFDDRIT---FPGDTAIAHQLIEHAV 374
P K L DDR T P AIAHQ+I V
Sbjct: 303 DPLLKNLPRTLDDRQTLHYIPPAGAIAHQMIRQWV 337
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.323 0.139 0.430
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,635,464
Number of Sequences: 60738
Number of extensions: 1019986
Number of successful extensions: 2060
Number of sequences better than 1.0e-05: 6
Number of HSP's better than 0.0 without gapping: 1
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 2041
Number of HSP's gapped (non-prelim): 7
length of query: 384
length of database: 30,389,216
effective HSP length: 108
effective length of query: 276
effective length of database: 23,829,512
effective search space: 6576945312
effective search space used: 6576945312
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)