ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIV0816 check: MH T KOG0616 Signal transduction mechanisms cAMP-dependent protein kinase catalytic subunit (PKA)
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIV0816 267933 269048 372
(372 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YPL203w [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 627 e-179
YKL166c [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 530 e-150
YJL164c [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 522 e-148
SPBC106.10 [T] KOG0616 cAMP-dependent protein kinase catalytic s... 423 e-118
Hs4506055 [T] KOG0616 cAMP-dependent protein kinase catalytic su... 352 4e-97
Hs4506057 [T] KOG0616 cAMP-dependent protein kinase catalytic su... 351 1e-96
CE15473 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 347 2e-95
Hs4826948 [T] KOG0616 cAMP-dependent protein kinase catalytic su... 341 9e-94
7297542 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 336 4e-92
Hs15619015 [T] KOG0616 cAMP-dependent protein kinase catalytic s... 330 2e-90
CE15475 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 328 6e-90
CE04603 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 290 2e-78
7301971 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 279 5e-75
Hs10835065 [T] KOG0616 cAMP-dependent protein kinase catalytic s... 270 3e-72
CE27166 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 256 5e-68
CE29092 [T] KOG0694 Serine/threonine protein kinase 255 6e-68
Hs4502023 [T] KOG0690 Serine/threonine protein kinase 254 1e-67
Hs4885549 [T] KOG0690 Serine/threonine protein kinase 253 2e-67
YKL126w [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 250 2e-66
Hs5453978 [T] KOG0614 cGMP-dependent protein kinase 250 2e-66
Hs5453972 [T] KOG0694 Serine/threonine protein kinase 250 3e-66
Hs10835242 [T] KOG0614 cGMP-dependent protein kinase 249 4e-66
Hs4885061 [T] KOG0690 Serine/threonine protein kinase 249 5e-66
Hs4506737 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 249 6e-66
CE15612 [T] KOG0690 Serine/threonine protein kinase 248 8e-66
7301734 [T] KOG0694 Serine/threonine protein kinase 248 8e-66
Hs4506739 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 248 1e-65
7300106 [T] KOG0690 Serine/threonine protein kinase 248 1e-65
Hs5032091 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 247 2e-65
Hs4885563 [T] KOG0694 Serine/threonine protein kinase 247 2e-65
CE14798 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 246 4e-65
SPCC24B10.07 [RT] KOG0598 Ribosomal protein S6 kinase and relate... 246 5e-65
Hs5453976 [T] KOG0694 Serine/threonine protein kinase 244 1e-64
Hs20127541 [RT] KOG0598 Ribosomal protein S6 kinase and related ... 244 1e-64
CE03979 [T] KOG0614 cGMP-dependent protein kinase 244 1e-64
YMR104c [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 243 3e-64
CE22045 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 243 4e-64
Hs20070247_2 [RT] KOG0598 Ribosomal protein S6 kinase and relate... 242 7e-64
7302860 [T] KOG0696 Serine/threonine protein kinase 240 2e-63
CE18169 [T] KOG0603 Ribosomal protein S6 kinase 240 3e-63
CE13014 [T] KOG0603 Ribosomal protein S6 kinase 240 3e-63
CE05274 [T] KOG0690 Serine/threonine protein kinase 239 5e-63
SPAC22E12.14c [RT] KOG0598 Ribosomal protein S6 kinase and relat... 239 6e-63
7296166 [T] KOG0614 cGMP-dependent protein kinase 239 6e-63
CE29298 [T] KOG0690 Serine/threonine protein kinase 238 8e-63
CE18646 [T] KOG0690 Serine/threonine protein kinase 238 8e-63
CE02586 [T] KOG0696 Serine/threonine protein kinase 238 1e-62
Hs22068916 [T] KOG0696 Serine/threonine protein kinase 237 2e-62
Hs20127450 [T] KOG0696 Serine/threonine protein kinase 237 2e-62
SPAC1B9.02c [RT] KOG0598 Ribosomal protein S6 kinase and related... 236 4e-62
7295426 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 236 4e-62
Hs4506067 [T] KOG0696 Serine/threonine protein kinase 235 9e-62
YHR205w [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 234 2e-61
Hs4506735 [T] KOG0603 Ribosomal protein S6 kinase 233 3e-61
SPBC12D12.04c [T] KOG0694 Serine/threonine protein kinase 232 6e-61
Hs20149547 [T] KOG0603 Ribosomal protein S6 kinase 232 8e-61
SPAC17G8.14c [T] KOG0694 Serine/threonine protein kinase 231 1e-60
Hs4759050 [T] KOG0603 Ribosomal protein S6 kinase 231 1e-60
Hs19923570 [T] KOG0603 Ribosomal protein S6 kinase 231 1e-60
Hs4506073 [T] KOG0694 Serine/threonine protein kinase 230 2e-60
Hs14758219 [T] KOG0694 Serine/threonine protein kinase 230 2e-60
At3g08720 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 230 2e-60
Hs13384594 [T] KOG0696 Serine/threonine protein kinase 228 8e-60
7295638 [T] KOG0603 Ribosomal protein S6 kinase 228 8e-60
At3g08730 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 228 1e-59
7303915 [T] KOG0694 Serine/threonine protein kinase 228 1e-59
7303914 [T] KOG0694 Serine/threonine protein kinase 228 1e-59
Hs5453974 [T] KOG0694 Serine/threonine protein kinase 227 2e-59
Hs4506071 [T] KOG0695 Serine/threonine protein kinase 227 2e-59
7302861 [T] KOG0696 Serine/threonine protein kinase 226 5e-59
Hs7657526 [T] KOG0603 Ribosomal protein S6 kinase 224 2e-58
Hs4759052 [T] KOG0603 Ribosomal protein S6 kinase 223 3e-58
SPCC4G3.08 [RT] KOG0598 Ribosomal protein S6 kinase and related ... 223 5e-58
Hs20535816 [T] KOG0695 Serine/threonine protein kinase 221 1e-57
Hs10864650 [T] KOG0695 Serine/threonine protein kinase 221 1e-57
Hs14735945 [T] KOG0694 Serine/threonine protein kinase 221 1e-57
7301972 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 221 2e-57
Hs5453970 [T] KOG0694 Serine/threonine protein kinase 219 4e-57
CE28744 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 219 5e-57
Hs7019489 [T] KOG0694 Serine/threonine protein kinase 219 7e-57
At2g20470 [R] KOG0605 NDR and related serine/threonine kinases 218 9e-57
At1g45160 [TR] KOG0606 Microtubule-associated serine/threonine k... 218 9e-57
At1g03920 [R] KOG0605 NDR and related serine/threonine kinases 218 1e-56
At1g30640 [R] KOG0605 NDR and related serine/threonine kinases 218 1e-56
7297611 [T] KOG0614 cGMP-dependent protein kinase 217 3e-56
CE17354 [T] KOG0694 Serine/threonine protein kinase 216 4e-56
CE17353 [T] KOG0694 Serine/threonine protein kinase 216 4e-56
7294770 [T] KOG0603 Ribosomal protein S6 kinase 215 7e-56
At5g62310 [TR] KOG0606 Microtubule-associated serine/threonine k... 214 2e-55
CE19898 [T] KOG0614 cGMP-dependent protein kinase 214 2e-55
CE19897 [T] KOG0614 cGMP-dependent protein kinase 214 2e-55
Hs18579683 [R] KOG0605 NDR and related serine/threonine kinases 213 4e-55
CE18699 [T] KOG0694 Serine/threonine protein kinase 212 6e-55
YBL105c [T] KOG0694 Serine/threonine protein kinase 212 8e-55
7303111 [T] KOG0695 Serine/threonine protein kinase 212 8e-55
Hs14149671 [TR] KOG0606 Microtubule-associated serine/threonine ... 211 1e-54
At5g09890 [R] KOG0605 NDR and related serine/threonine kinases 211 2e-54
CE28760 [R] KOG0605 NDR and related serine/threonine kinases 210 3e-54
Hs17455844 [TR] KOG0606 Microtubule-associated serine/threonine ... 209 5e-54
Hs4505695 [T] KOG0592 3-phosphoinositide-dependent protein kinas... 209 7e-54
At3g23310 [R] KOG0605 NDR and related serine/threonine kinases 208 9e-54
Hs20543401 [TR] KOG0606 Microtubule-associated serine/threonine ... 207 2e-53
CE02604 [T] KOG0695 Serine/threonine protein kinase 206 6e-53
At4g14350 [R] KOG0605 NDR and related serine/threonine kinases 206 6e-53
At3g10540 [T] KOG0592 3-phosphoinositide-dependent protein kinas... 204 1e-52
CE20493 [TR] KOG0606 Microtubule-associated serine/threonine kin... 203 3e-52
YCR091w [R] KOG0610 Putative serine/threonine protein kinase 203 4e-52
7293735 [R] KOG0605 NDR and related serine/threonine kinases 201 1e-51
SPBC1861.09 [R] KOG0610 Putative serine/threonine protein kinase 201 1e-51
ECU07g0520 [T] KOG0616 cAMP-dependent protein kinase catalytic s... 201 1e-51
At1g48490 [TR] KOG0606 Microtubule-associated serine/threonine k... 201 1e-51
YNR047w [R] KOG0610 Putative serine/threonine protein kinase 200 3e-51
Hs4885583 [T] KOG0612 Rho-associated coiled-coil containing prot... 198 1e-50
7294265 [TR] KOG0606 Microtubule-associated serine/threonine kin... 197 2e-50
Hs6005814 [R] KOG0605 NDR and related serine/threonine kinases 196 4e-50
CE05507 [T] KOG0603 Ribosomal protein S6 kinase 196 4e-50
At5g04510 [T] KOG0592 3-phosphoinositide-dependent protein kinas... 196 4e-50
Hs4759044 [T] KOG0612 Rho-associated coiled-coil containing prot... 196 5e-50
Hs20536595 [T] KOG0612 Rho-associated coiled-coil containing pro... 196 5e-50
At3g17850 [TR] KOG0606 Microtubule-associated serine/threonine k... 196 6e-50
SPAC4G8.05 [R] KOG0610 Putative serine/threonine protein kinase 194 2e-49
Hs4505831 [T] KOG0612 Rho-associated coiled-coil containing prot... 194 2e-49
Hs16357474_1 [T] KOG0612 Rho-associated coiled-coil containing p... 192 7e-49
CE11916 [T] KOG0612 Rho-associated coiled-coil containing protei... 191 2e-48
Hs4758666 [D] KOG0608 Warts/lats-like serine threonine kinases 189 6e-48
Hs8923754 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 188 1e-47
SPAC821.12 [R] KOG0605 NDR and related serine/threonine kinases 187 2e-47
At1g30270 [T] KOG0583 Serine/threonine protein kinase 186 5e-47
7291742_1 [T] KOG0612 Rho-associated coiled-coil containing prot... 185 8e-47
CE24761 [D] KOG0580 Serine/threonine protein kinase 185 1e-46
CE13844 [D] KOG0608 Warts/lats-like serine threonine kinases 184 2e-46
At2g45490 [D] KOG0580 Serine/threonine protein kinase 183 4e-46
7301980 [D] KOG0608 Warts/lats-like serine threonine kinases 181 2e-45
YPL209c [D] KOG0580 Serine/threonine protein kinase 180 3e-45
At2g25090 [T] KOG0583 Serine/threonine protein kinase 180 3e-45
At5g25110 [T] KOG0583 Serine/threonine protein kinase 180 3e-45
CE08098 [T] KOG0612 Rho-associated coiled-coil containing protei... 179 4e-45
SPBC4C3.11 [T] KOG0592 3-phosphoinositide-dependent protein kina... 179 6e-45
7293249 [T] KOG0612 Rho-associated coiled-coil containing protei... 179 6e-45
At1g29230 [T] KOG0583 Serine/threonine protein kinase 178 1e-44
YOL100w [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 177 3e-44
SPCC320.12c [D] KOG0580 Serine/threonine protein kinase 177 3e-44
At4g18700 [T] KOG0583 Serine/threonine protein kinase 176 6e-44
At5g45820 [T] KOG0583 Serine/threonine protein kinase 175 8e-44
At4g32830 [D] KOG0580 Serine/threonine protein kinase 174 1e-43
7299536 [D] KOG0580 Serine/threonine protein kinase 174 1e-43
Hs10334852 [T] KOG0612 Rho-associated coiled-coil containing pro... 174 2e-43
YBR028c [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 174 2e-43
Hs4501971 [T] KOG0986 G protein-coupled receptor kinase 174 2e-43
CE03492 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 174 2e-43
CE21025 [D] KOG0580 Serine/threonine protein kinase 173 3e-43
At2g26980 [T] KOG0583 Serine/threonine protein kinase 173 3e-43
CE02074 [T] KOG0986 G protein-coupled receptor kinase 173 4e-43
At2g25880 [D] KOG0580 Serine/threonine protein kinase 173 4e-43
At1g53700 [R] KOG0610 Putative serine/threonine protein kinase 173 4e-43
At5g35410 [T] KOG0583 Serine/threonine protein kinase 171 1e-42
At2g34180 [T] KOG0583 Serine/threonine protein kinase 171 1e-42
At4g24400 [T] KOG0583 Serine/threonine protein kinase 171 2e-42
At5g45810 [T] KOG0583 Serine/threonine protein kinase 170 3e-42
Hs4885055 [T] KOG0986 G protein-coupled receptor kinase 170 4e-42
At5g10930 [T] KOG0583 Serine/threonine protein kinase 170 4e-42
At3g01090 [T] KOG0583 Serine/threonine protein kinase 169 5e-42
ECU01g1320 [T] KOG0612 Rho-associated coiled-coil containing pro... 169 6e-42
At3g14370 [R] KOG0610 Putative serine/threonine protein kinase 169 6e-42
Hs4507273 [D] KOG0580 Serine/threonine protein kinase 169 8e-42
At5g39440 [T] KOG0583 Serine/threonine protein kinase 168 1e-41
7294566 [T] KOG0612 Rho-associated coiled-coil containing protei... 167 2e-41
7290150 [T] KOG0583 Serine/threonine protein kinase 167 2e-41
Hs4759178 [D] KOG0580 Serine/threonine protein kinase 165 9e-41
Hs4504101 [T] KOG0986 G protein-coupled receptor kinase 165 9e-41
At1g01140 [T] KOG0583 Serine/threonine protein kinase 165 9e-41
Hs4506529 [T] KOG0986 G protein-coupled receptor kinase 165 1e-40
Hs14196445 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 165 1e-40
Hs4507275 [D] KOG0580 Serine/threonine protein kinase 164 1e-40
At4g30960 [T] KOG0583 Serine/threonine protein kinase 164 1e-40
At3g29160 [T] KOG0583 Serine/threonine protein kinase 164 1e-40
At2g30360 [T] KOG0583 Serine/threonine protein kinase 164 1e-40
At5g07070 [T] KOG0583 Serine/threonine protein kinase 164 2e-40
Hs5453964 [T] KOG0583 Serine/threonine protein kinase 164 3e-40
At5g01810 [T] KOG0583 Serine/threonine protein kinase 164 3e-40
SPAC24B11.11c [R] KOG0605 NDR and related serine/threonine kinases 163 3e-40
CE28643 [T] KOG0583 Serine/threonine protein kinase 162 7e-40
At2g34650 [R] KOG0610 Putative serine/threonine protein kinase 161 1e-39
YDR466w [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 161 2e-39
Hs4885349 [T] KOG0986 G protein-coupled receptor kinase 161 2e-39
CE07458 [T] KOG0583 Serine/threonine protein kinase 161 2e-39
At5g58380 [T] KOG0583 Serine/threonine protein kinase 161 2e-39
SPCC576.15c [T] KOG0592 3-phosphoinositide-dependent protein kin... 160 2e-39
Hs18552621 [R] KOG0597 Serine-threonine protein kinase FUSED 160 2e-39
Hs5453966 [T] KOG0583 Serine/threonine protein kinase 159 5e-39
Hs4885347 [T] KOG0986 G protein-coupled receptor kinase 158 1e-38
At4g33080 [R] KOG0605 NDR and related serine/threonine kinases 158 1e-38
Hs20545245 [D] KOG0588 Serine/threonine protein kinase 158 1e-38
CE00847 [T] KOG0583 Serine/threonine protein kinase 158 1e-38
YDR490c [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 157 2e-38
CE28218 [D] KOG0588 Serine/threonine protein kinase 157 2e-38
HsM4507279 [D] KOG0580 Serine/threonine protein kinase 157 3e-38
At2g19400 [R] KOG0605 NDR and related serine/threonine kinases 156 5e-38
CE01554 [T] KOG0986 G protein-coupled receptor kinase 155 7e-38
At5g01820 [T] KOG0583 Serine/threonine protein kinase 155 7e-38
CE29300 [T] KOG0694 Serine/threonine protein kinase 155 1e-37
CE29299 [T] KOG0694 Serine/threonine protein kinase 155 1e-37
7302050 [T] KOG0986 G protein-coupled receptor kinase 155 1e-37
At5g57630 [T] KOG0583 Serine/threonine protein kinase 154 2e-37
YPR111w [R] KOG0605 NDR and related serine/threonine kinases 154 2e-37
SPCC74.03c [T] KOG0583 Serine/threonine protein kinase 154 2e-37
CE27768 [R] KOG0586 Serine/threonine protein kinase 154 2e-37
CE23838 [R] KOG0586 Serine/threonine protein kinase 154 2e-37
7297776 [D] KOG0580 Serine/threonine protein kinase 154 2e-37
Hs9966875 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 154 3e-37
YDR477w [T] KOG0583 Serine/threonine protein kinase 153 4e-37
Hs8923922 [R] KOG0586 Serine/threonine protein kinase 153 4e-37
SPCC417.06c [R] KOG0605 NDR and related serine/threonine kinases 152 8e-37
SPCC18B5.11c [D] KOG0615 Serine/threonine protein kinase Chk2 an... 152 8e-37
7294217 [D] KOG0588 Serine/threonine protein kinase 152 1e-36
Hs22062450 [R] KOG0586 Serine/threonine protein kinase 151 2e-36
CE25046 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 151 2e-36
7302464 [R] KOG0586 Serine/threonine protein kinase 151 2e-36
Hs9845489 [R] KOG0586 Serine/threonine protein kinase 150 3e-36
Hs9845487 [R] KOG0586 Serine/threonine protein kinase 150 3e-36
CE07156 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 150 4e-36
7299437 [R] KOG0586 Serine/threonine protein kinase 150 4e-36
7290249 [R] KOG0586 Serine/threonine protein kinase 150 4e-36
HsM4505103 [R] KOG0586 Serine/threonine protein kinase 149 5e-36
At4g14580 [T] KOG0583 Serine/threonine protein kinase 149 5e-36
7299438 [R] KOG0586 Serine/threonine protein kinase 149 5e-36
YGR092w [R] KOG0605 NDR and related serine/threonine kinases 149 6e-36
Hs21361433 [D] KOG0575 Polo-like serine/threonine protein kinase 149 6e-36
HsM7657627 [D] KOG0575 Polo-like serine/threonine protein kinase 149 8e-36
Hs4502553 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 149 8e-36
Hs6005850 [D] KOG0615 Serine/threonine protein kinase Chk2 and r... 148 1e-35
7293512 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 148 1e-35
At1g50230 [R] KOG0597 Serine-threonine protein kinase FUSED 147 2e-35
Hs14728804 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 147 3e-35
Hs13899225 [R] KOG0586 Serine/threonine protein kinase 147 3e-35
YKL101w [D] KOG0588 Serine/threonine protein kinase 146 4e-35
At4g40010 [T] KOG0583 Serine/threonine protein kinase 146 5e-35
At3g17510 [T] KOG0583 Serine/threonine protein kinase 146 5e-35
ECU07g0360 [D] KOG0580 Serine/threonine protein kinase 145 7e-35
7304311 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 145 7e-35
At2g38490 [T] KOG0583 Serine/threonine protein kinase 145 9e-35
Hs13569922 [R] KOG0611 Predicted serine/threonine protein kinase 144 2e-34
CE05780 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 143 5e-34
CE26793_1 [R] KOG0611 Predicted serine/threonine protein kinase 143 5e-34
7296450 [D] KOG0575 Polo-like serine/threonine protein kinase 142 6e-34
Hs14916455 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 142 8e-34
Hs14141724 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase ... 142 8e-34
7298652 [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 142 1e-33
Hs14770402 [R] KOG0586 Serine/threonine protein kinase 141 1e-33
At3g23000 [T] KOG0583 Serine/threonine protein kinase 141 1e-33
Hs7661974 [T] KOG0583 Serine/threonine protein kinase 141 2e-33
Hs21166359 [T] KOG0986 G protein-coupled receptor kinase 141 2e-33
Hs7706286 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase E... 140 2e-33
Hs21361643 [T] KOG4717 Serine/threonine protein kinase 140 3e-33
At1g78290 [T] KOG0583 Serine/threonine protein kinase 140 4e-33
Hs4758128_2 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase... 140 4e-33
YLR096w [T] KOG0583 Serine/threonine protein kinase 138 1e-32
Hs14776113 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 138 1e-32
At2g20040 [T] KOG0616 cAMP-dependent protein kinase catalytic su... 138 1e-32
At1g09000 [T] KOG0198 MEKK and related serine/threonine protein ... 137 3e-32
YCL024w [T] KOG0583 Serine/threonine protein kinase 137 3e-32
Hs7662170 [R] KOG0611 Predicted serine/threonine protein kinase 137 3e-32
Hs4506075 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD... 137 3e-32
Hs18959200 [D] KOG0608 Warts/lats-like serine threonine kinases 137 3e-32
CE28739 [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 136 4e-32
CE17284 [T] KOG0583 Serine/threonine protein kinase 136 6e-32
SPAC23C11.16 [D] KOG0575 Polo-like serine/threonine protein kinase 135 7e-32
CE28740 [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 135 7e-32
At3g06030 [T] KOG0198 MEKK and related serine/threonine protein ... 135 7e-32
7299322 [R] KOG0611 Predicted serine/threonine protein kinase 135 7e-32
YDR507c [D] KOG0588 Serine/threonine protein kinase 135 1e-31
Hs22066167 [RT] KOG0598 Ribosomal protein S6 kinase and related ... 135 1e-31
YPL141c [T] KOG0583 Serine/threonine protein kinase 135 1e-31
7293666 [D] KOG0575 Polo-like serine/threonine protein kinase 135 1e-31
Hs5031689 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD... 134 2e-31
Hs22043888 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 134 2e-31
7304358 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 134 2e-31
YDR122w [T] KOG0583 Serine/threonine protein kinase 134 2e-31
SPACUNK12.02c [T] KOG0032 Ca2+/calmodulin-dependent protein kina... 134 2e-31
At3g13530 [T] KOG0198 MEKK and related serine/threonine protein ... 134 2e-31
7303211 [T] KOG4717 Serine/threonine protein kinase 134 2e-31
At3g61960 [OUT] KOG0595 Serine/threonine-protein kinase involved... 134 3e-31
At3g45240 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase k... 134 3e-31
At3g07980 [T] KOG0198 MEKK and related serine/threonine protein ... 134 3e-31
At1g48260 [T] KOG0583 Serine/threonine protein kinase 134 3e-31
YDL101c [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 133 4e-31
CE12518 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 133 4e-31
At1g61950 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 133 4e-31
At1g54960 [T] KOG0198 MEKK and related serine/threonine protein ... 133 4e-31
Hs21359873 [D] KOG0575 Polo-like serine/threonine protein kinase 133 5e-31
Hs19923468 [T] KOG4236 Serine/threonine protein kinase PKC mu/PK... 133 5e-31
SPBC4F6.06 [T] KOG0583 Serine/threonine protein kinase 132 6e-31
At5g19360 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 132 6e-31
YNL161w [R] KOG0605 NDR and related serine/threonine kinases 132 1e-30
CE28061 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 132 1e-30
CE28060 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 132 1e-30
CE28059 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 132 1e-30
CE28058 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 132 1e-30
CE28057 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 132 1e-30
CE28056 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 132 1e-30
CE28055 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 132 1e-30
CE28054 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 132 1e-30
CE28053 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 132 1e-30
CE28051 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 132 1e-30
At1g76040 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 131 1e-30
7299160 [OUT] KOG0595 Serine/threonine-protein kinase involved i... 131 1e-30
CE28479 [T] KOG0583 Serine/threonine protein kinase 131 2e-30
At5g60550 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase k... 131 2e-30
YFL033c [R] KOG0605 NDR and related serine/threonine kinases 130 2e-30
SPAC57A10.02 [D] KOG0588 Serine/threonine protein kinase 130 2e-30
HsM4826916 [D] KOG0575 Polo-like serine/threonine protein kinase 130 2e-30
At5g12180 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 130 2e-30
YPL150w [T] KOG0583 Serine/threonine protein kinase 130 4e-30
At4g33950 [T] KOG0583 Serine/threonine protein kinase 130 4e-30
At3g20410 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 130 4e-30
YMR001c [D] KOG0575 Polo-like serine/threonine protein kinase 129 5e-30
SPBC21.06c [T] KOG0198 MEKK and related serine/threonine protein... 129 5e-30
7302570 [R] KOG0586 Serine/threonine protein kinase 129 5e-30
YOR233w [T] KOG0583 Serine/threonine protein kinase 129 9e-30
Hs20127418 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase ... 129 9e-30
At3g52890 [R] KOG0610 Putative serine/threonine protein kinase 129 9e-30
YPL153c [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 128 1e-29
Hs14249562 [TR] KOG0606 Microtubule-associated serine/threonine ... 128 1e-29
7292679 [G] KOG0599 Phosphorylase kinase gamma subunit 128 2e-29
At2g37840 [OUT] KOG0595 Serine/threonine-protein kinase involved... 127 2e-29
At1g08650 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 127 2e-29
At1g49180_1 [OUT] KOG0595 Serine/threonine-protein kinase involv... 127 2e-29
HsM8923212 [T] KOG4717 Serine/threonine protein kinase 127 3e-29
7300437 [TR] KOG0606 Microtubule-associated serine/threonine kin... 127 3e-29
CE18967 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD a... 127 3e-29
At2g23030 [T] KOG0583 Serine/threonine protein kinase 127 3e-29
SPAC23H4.02 [T] KOG0583 Serine/threonine protein kinase 126 5e-29
ECU10g0570 [RT] KOG0598 Ribosomal protein S6 kinase and related ... 126 5e-29
At3g04530 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 126 5e-29
At5g08590 [T] KOG0583 Serine/threonine protein kinase 126 6e-29
At3g27580 [R] KOG0610 Putative serine/threonine protein kinase 126 6e-29
YFR014c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 125 8e-29
Hs17933758 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase ... 125 8e-29
CE20167 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD a... 125 8e-29
Hs4502557 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 125 1e-28
Hs22042851 [T] KOG0986 G protein-coupled receptor kinase 125 1e-28
SPBC32C12.03c [T] KOG0583 Serine/threonine protein kinase 124 2e-28
At5g63650 [T] KOG0583 Serine/threonine protein kinase 124 2e-28
At4g04720 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 124 2e-28
At1g50700 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 124 2e-28
At1g12680 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 124 2e-28
YJL095w [T] KOG0198 MEKK and related serine/threonine protein ki... 124 2e-28
SPCC162.10 [RT] KOG0598 Ribosomal protein S6 kinase and related ... 124 2e-28
Hs4557511 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 124 3e-28
Hs4505599 [T] KOG0578 p21-activated serine/threonine protein kinase 124 3e-28
CE28251 [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 124 3e-28
At2g36350 [R] KOG0610 Putative serine/threonine protein kinase 124 3e-28
At1g53570 [T] KOG0198 MEKK and related serine/threonine protein ... 124 3e-28
SPAC644.06c [D] KOG0588 Serine/threonine protein kinase 123 4e-28
CE20142 [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 123 4e-28
7298926 [T] KOG0578 p21-activated serine/threonine protein kinase 123 4e-28
SPCC1259.13 [D] KOG0590 Checkpoint kinase and related serine/thr... 123 5e-28
SPAC890.03 [T] KOG0583 Serine/threonine protein kinase 123 5e-28
Hs14150045 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase ... 123 5e-28
CE15235 [R] KOG0589 Serine/threonine protein kinase 123 5e-28
At1g60940 [T] KOG0583 Serine/threonine protein kinase 123 5e-28
SPAC23A1.06c [T] KOG0032 Ca2+/calmodulin-dependent protein kinas... 122 6e-28
Hs5730055 [D] KOG0575 Polo-like serine/threonine protein kinase 122 6e-28
At3g12690 [R] KOG0610 Putative serine/threonine protein kinase 122 6e-28
At3g10660 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 122 6e-28
YOL016c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 122 8e-28
SPBC1604.14c [T] KOG0578 p21-activated serine/threonine protein ... 122 8e-28
At2g38910 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 122 8e-28
Hs4505785 [G] KOG0599 Phosphorylase kinase gamma subunit 122 1e-27
Hs14771959 [T] KOG0578 p21-activated serine/threonine protein ki... 122 1e-27
Hs14670383 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 122 1e-27
At5g66880 [T] KOG0583 Serine/threonine protein kinase 122 1e-27
Hs4758700 [T] KOG0604 MAP kinase-activated protein kinase 2 121 1e-27
At4g21940 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 121 1e-27
At1g10940 [T] KOG0583 Serine/threonine protein kinase 121 1e-27
Hs20547806 [R] KOG0589 Serine/threonine protein kinase 121 2e-27
CE27297 [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 121 2e-27
7293496 [R] KOG0597 Serine-threonine protein kinase FUSED 121 2e-27
SPCC1450.11c [R] KOG0605 NDR and related serine/threonine kinases 120 2e-27
CE16081 [T] KOG0583 Serine/threonine protein kinase 120 2e-27
Hs4826684_1 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase... 120 2e-27
Hs7382496 [T] KOG0578 p21-activated serine/threonine protein kinase 120 3e-27
At5g55910 [R] KOG0610 Putative serine/threonine protein kinase 120 3e-27
At4g09570 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 120 3e-27
7300149 [T] KOG0578 p21-activated serine/threonine protein kinase 120 4e-27
Hs20545357 [T] KOG0583 Serine/threonine protein kinase 119 6e-27
ECU03g0980 [T] KOG0583 Serine/threonine protein kinase 119 6e-27
CE20564 [T] KOG0578 p21-activated serine/threonine protein kinase 119 6e-27
CE05425 [T] KOG0578 p21-activated serine/threonine protein kinase 119 6e-27
Hs4507277_1 [R] KOG0589 Serine/threonine protein kinase 119 6e-27
At2g26700_2 [R] KOG0610 Putative serine/threonine protein kinase 119 6e-27
HsM5454174 [T] KOG0201 Serine/threonine protein kinase 119 7e-27
Hs4505601 [T] KOG0578 p21-activated serine/threonine protein kinase 119 7e-27
Hs4505373 [V] KOG1826 Ras GTPase activating protein RasGAP/neuro... 119 7e-27
Hs21361358 [T] KOG0201 Serine/threonine protein kinase 119 7e-27
At5g03640 [R] KOG0610 Putative serine/threonine protein kinase 119 7e-27
At1g16440 [R] KOG0610 Putative serine/threonine protein kinase 119 7e-27
7290629 [T] KOG0604 MAP kinase-activated protein kinase 2 119 7e-27
YGL180w [OUT] KOG0595 Serine/threonine-protein kinase involved i... 119 9e-27
Hs10863901 [T] KOG0604 MAP kinase-activated protein kinase 2 119 9e-27
CE21615 [T] KOG0578 p21-activated serine/threonine protein kinase 119 9e-27
At4g26610 [R] KOG0610 Putative serine/threonine protein kinase 119 9e-27
At1g35670 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 119 9e-27
Hs4758016 [D] KOG0575 Polo-like serine/threonine protein kinase 118 1e-26
CE18608 [R] KOG0594 Protein kinase PCTAIRE and related kinases 118 1e-26
CE17343 [T] KOG0583 Serine/threonine protein kinase 118 1e-26
CE02377 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 118 1e-26
At5g23580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 118 1e-26
At3g49370 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 118 1e-26
7303019 [Z] KOG0613 Projectin/twitchin and related proteins 118 1e-26
SPAC1F5.09c [T] KOG0578 p21-activated serine/threonine protein k... 118 2e-26
Hs9910476 [T] KOG0578 p21-activated serine/threonine protein kinase 118 2e-26
Hs16950621 [Z] KOG0613 Projectin/twitchin and related proteins 118 2e-26
Hs16950613 [Z] KOG0613 Projectin/twitchin and related proteins 118 2e-26
Hs16950611 [Z] KOG0613 Projectin/twitchin and related proteins 118 2e-26
Hs16950601 [Z] KOG0613 Projectin/twitchin and related proteins 118 2e-26
Hs14589904 [T] KOG0604 MAP kinase-activated protein kinase 2 118 2e-26
CE26649 [D] KOG0575 Polo-like serine/threonine protein kinase 118 2e-26
At4g04740 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 118 2e-26
SPBC1D7.05c [T] KOG0198 MEKK and related serine/threonine protei... 117 2e-26
Hs7657214 [T] KOG0583 Serine/threonine protein kinase 117 2e-26
At5g40030 [R] KOG0610 Putative serine/threonine protein kinase 117 2e-26
7291910 [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 117 2e-26
YCR073c [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and r... 117 3e-26
YAR019c [T] KOG0198 MEKK and related serine/threonine protein ki... 117 3e-26
SPAC14C4.03 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase... 117 3e-26
Hs20479818 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 117 3e-26
ECU01g0630 [D] KOG0575 Polo-like serine/threonine protein kinase 117 3e-26
At1g12580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 117 3e-26
CE22877 [D] KOG0575 Polo-like serine/threonine protein kinase 117 4e-26
At3g15220 [T] KOG0201 Serine/threonine protein kinase 117 4e-26
At2g44830 [R] KOG0610 Putative serine/threonine protein kinase 117 4e-26
At1g79250 [R] KOG0610 Putative serine/threonine protein kinase 117 4e-26
CE24516 [OUT] KOG0595 Serine/threonine-protein kinase involved i... 116 5e-26
CE09360 [Z] KOG0613 Projectin/twitchin and related proteins 116 5e-26
At4g35310 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 116 5e-26
At2g35890 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 116 5e-26
Hs4502567_1 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase... 116 5e-26
Hs5031975 [T] KOG0578 p21-activated serine/threonine protein kinase 116 6e-26
HsM4505191 [T] KOG0607 MAP kinase-interacting kinase and related... 115 1e-25
CE27583 [T] KOG0604 MAP kinase-activated protein kinase 2 115 1e-25
CE17545 [T] KOG0604 MAP kinase-activated protein kinase 2 115 1e-25
At5g04870 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 115 1e-25
At1g53165 [T] KOG0201 Serine/threonine protein kinase 115 1e-25
7290841 [D] KOG0591 NIMA (never in mitosis)-related G2-specific ... 115 1e-25
Hs21450709 [RT] KOG0598 Ribosomal protein S6 kinase and related ... 115 1e-25
CE06635 [Z] KOG0613 Projectin/twitchin and related proteins 115 1e-25
CE06634 [Z] KOG0613 Projectin/twitchin and related proteins 115 1e-25
At5g47750 [R] KOG0610 Putative serine/threonine protein kinase 115 1e-25
At2g41860 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 115 1e-25
CE28674 [T] KOG0201 Serine/threonine protein kinase 114 2e-25
CE18454 [T] KOG4717 Serine/threonine protein kinase 114 2e-25
CE07510 [T] KOG0201 Serine/threonine protein kinase 114 2e-25
At3g56760 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 114 2e-25
At2g41140 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 114 2e-25
At2g17290 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 114 2e-25
Hs8393810_1 [T] KOG0587 Traf2- and Nck-interacting kinase and re... 114 2e-25
Hs20544910_1 [T] KOG0587 Traf2- and Nck-interacting kinase and r... 114 2e-25
YGL179c [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kin... 114 3e-25
HsM4506035 [T] KOG0604 MAP kinase-activated protein kinase 2 114 3e-25
Hs5453882 [G] KOG0599 Phosphorylase kinase gamma subunit 114 3e-25
At5g56580 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 114 3e-25
At4g08500 [T] KOG0198 MEKK and related serine/threonine protein ... 114 3e-25
At3g50500 [T] KOG0583 Serine/threonine protein kinase 114 3e-25
YHR102w [T] KOG0201 Serine/threonine protein kinase 113 4e-25
YHL007c [T] KOG0578 p21-activated serine/threonine protein kinase 113 4e-25
Hs4505153 [T] KOG0198 MEKK and related serine/threonine protein ... 113 4e-25
Hs14777335 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 113 4e-25
CE18366 [T] KOG0583 Serine/threonine protein kinase 113 4e-25
SPAC1F3.02c [T] KOG0198 MEKK and related serine/threonine protei... 113 5e-25
Hs21237768 [T] KOG0604 MAP kinase-activated protein kinase 2 113 5e-25
Hs21237765 [T] KOG0604 MAP kinase-activated protein kinase 2 113 5e-25
At4g29810 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 113 5e-25
SPAC2C4.14c [T] KOG0201 Serine/threonine protein kinase 112 7e-25
Hs19424132 [D] KOG0591 NIMA (never in mitosis)-related G2-specif... 112 7e-25
At5g24430 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 112 7e-25
At3g44200 [R] KOG0589 Serine/threonine protein kinase 112 7e-25
At1g18890 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 112 7e-25
7301213 [R] KOG0589 Serine/threonine protein kinase 112 7e-25
Hs22057171 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 112 9e-25
Hs22043324 [T] KOG0603 Ribosomal protein S6 kinase 112 9e-25
Hs19923407 [D] KOG0591 NIMA (never in mitosis)-related G2-specif... 112 9e-25
Hs14754789 [OUT] KOG0595 Serine/threonine-protein kinase involve... 112 9e-25
At1g69220 [T] KOG0576 Mitogen-activated protein kinase kinase ki... 112 9e-25
Hs20070158 [T] KOG0201 Serine/threonine protein kinase 112 1e-24
CE27670 [T] KOG0578 p21-activated serine/threonine protein kinase 112 1e-24
CE20636 [D] KOG0590 Checkpoint kinase and related serine/threoni... 112 1e-24
At4g38230 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 112 1e-24
SPCC297.03 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase ... 111 1e-24
Hs15451902 [T] KOG0576 Mitogen-activated protein kinase kinase k... 111 1e-24
ECU08g1480 [R] KOG0586 Serine/threonine protein kinase 111 1e-24
Hs4507831 [OUT] KOG0595 Serine/threonine-protein kinase involved... 111 2e-24
At1g54510 [R] KOG0589 Serine/threonine protein kinase 111 2e-24
YLR362w [T] KOG0198 MEKK and related serine/threonine protein ki... 110 3e-24
SPAC9G1.09 [T] KOG0201 Serine/threonine protein kinase 110 3e-24
Hs6031180 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and... 110 3e-24
Hs5803088 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and... 110 3e-24
Hs4502803 [D] KOG0590 Checkpoint kinase and related serine/threo... 110 3e-24
Hs21735556 [T] KOG0198 MEKK and related serine/threonine protein... 110 3e-24
At4g31170 [T] KOG0192 Tyrosine kinase specific for activated (GT... 110 3e-24
>YPL203w [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 380
Score = 627 bits (1616), Expect = e-179
Identities = 292/329 (88%), Positives = 315/329 (94%)
Query: 44 SLLPQRSTVSKGKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQ 103
S LPQ+S VSKGKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKK Q+++MKQ
Sbjct: 52 SQLPQKSLVSKGKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKQQVVKMKQ 111
Query: 104 IEHTNDERRMLKLVEHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAK 163
+EHTNDERRMLKLVEHPFLIRMWGTFQD+RN+FMVMDYIEGGELFSLLRKSQRFPNPVAK
Sbjct: 112 VEHTNDERRMLKLVEHPFLIRMWGTFQDARNIFMVMDYIEGGELFSLLRKSQRFPNPVAK 171
Query: 164 FYAAEVTLALEYLHSHNIIYRDLKPENILLDRNGHIKITDFGFAKEVITVTWTLCGTPDY 223
FYAAEV LALEYLH+HNIIYRDLKPENILLDRNGHIKITDFGFAKEV TVTWTLCGTPDY
Sbjct: 172 FYAAEVILALEYLHAHNIIYRDLKPENILLDRNGHIKITDFGFAKEVQTVTWTLCGTPDY 231
Query: 224 IAPEVITTKPYNKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFFHPD 283
IAPEVITTKPYNKSVDWWSLG+LI+EMLAGYTPFYD TPMKTYEKIL G+VVYPP+FHPD
Sbjct: 232 IAPEVITTKPYNKSVDWWSLGVLIYEMLAGYTPFYDTTPMKTYEKILQGKVVYPPYFHPD 291
Query: 284 VVDLLGKLITADLTRRLGNLQSGPDDIKSHPWFAEVIWEKLVAKDIETPYEPPIAVGVGD 343
VVDLL KLITADLTRR+GNLQSG DIK+HPWF+EV+WE+L+AKDIETPYEPPI G+GD
Sbjct: 292 VVDLLSKLITADLTRRIGNLQSGSRDIKAHPWFSEVVWERLLAKDIETPYEPPITSGIGD 351
Query: 344 SSLFDQYPEEQLDYGVQGEDPYGQYFLDF 372
+SLFDQYPEEQLDYG+QG+DPY +YF DF
Sbjct: 352 TSLFDQYPEEQLDYGIQGDDPYAEYFQDF 380
>YKL166c [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 398
Score = 530 bits (1364), Expect = e-150
Identities = 248/331 (74%), Positives = 286/331 (85%), Gaps = 2/331 (0%)
Query: 42 KESLLPQRSTVSKGKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRM 101
K+ +L R T GKY+L DFQI+RTLGTGSFGRVHL+RS HNGR+YA+K LKKH I+++
Sbjct: 70 KKPMLQYRDT--SGKYSLSDFQILRTLGTGSFGRVHLIRSNHNGRFYALKTLKKHTIVKL 127
Query: 102 KQIEHTNDERRMLKLVEHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPV 161
KQ+EHTNDERRML +V HPF+IRMWGTFQDS+ +FMVMDYIEGGELFSLLRKSQRFPNPV
Sbjct: 128 KQVEHTNDERRMLSIVSHPFIIRMWGTFQDSQQVFMVMDYIEGGELFSLLRKSQRFPNPV 187
Query: 162 AKFYAAEVTLALEYLHSHNIIYRDLKPENILLDRNGHIKITDFGFAKEVITVTWTLCGTP 221
AKFYAAEV LALEYLHS +IIYRDLKPENILLD+NGHIKITDFGFAK V VT+TLCGTP
Sbjct: 188 AKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFAKYVPDVTYTLCGTP 247
Query: 222 DYIAPEVITTKPYNKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFFH 281
DYIAPEV++TKPYNKSVDWWS G+LI+EMLAGYTPFY+ MKTYE IL E+ +PPFFH
Sbjct: 248 DYIAPEVVSTKPYNKSVDWWSFGVLIYEMLAGYTPFYNSNTMKTYENILNAELKFPPFFH 307
Query: 282 PDVVDLLGKLITADLTRRLGNLQSGPDDIKSHPWFAEVIWEKLVAKDIETPYEPPIAVGV 341
PD DLL KLIT DL+ RLGNLQ+G +D+K+HPWF EVIWEKL+A+ IETPYEPPI G
Sbjct: 308 PDAQDLLKKLITRDLSERLGNLQNGSEDVKNHPWFNEVIWEKLLARYIETPYEPPIQQGQ 367
Query: 342 GDSSLFDQYPEEQLDYGVQGEDPYGQYFLDF 372
GD+S FD+YPEE+ +YG+QGEDPY +F
Sbjct: 368 GDTSQFDRYPEEEFNYGIQGEDPYMDLMKEF 398
>YJL164c [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 397
Score = 522 bits (1344), Expect = e-148
Identities = 246/339 (72%), Positives = 288/339 (84%), Gaps = 2/339 (0%)
Query: 34 TDYLLAQQKESLLPQRSTVSKGKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVL 93
T Y Q K+ + R TV G +FQI+RTLGTGSFGRVHL+RS HNGRYYA+KVL
Sbjct: 61 TYYNEEQYKQFIAQARVTV--GSIVYKNFQILRTLGTGSFGRVHLIRSRHNGRYYAMKVL 118
Query: 94 KKHQIIRMKQIEHTNDERRMLKLVEHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRK 153
KK ++R+KQ+EHTNDER ML +V HPF+IRMWGTFQD++ +FM+MDYIEGGELFSLLRK
Sbjct: 119 KKEIVVRLKQVEHTNDERLMLSIVTHPFIIRMWGTFQDAQQIFMIMDYIEGGELFSLLRK 178
Query: 154 SQRFPNPVAKFYAAEVTLALEYLHSHNIIYRDLKPENILLDRNGHIKITDFGFAKEVITV 213
SQRFPNPVAKFYAAEV LALEYLHS +IIYRDLKPENILLD+NGHIKITDFGFAK V V
Sbjct: 179 SQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFAKYVPDV 238
Query: 214 TWTLCGTPDYIAPEVITTKPYNKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGE 273
T+TLCGTPDYIAPEV++TKPYNKS+DWWS GILI+EMLAGYTPFYD MKTYEKIL E
Sbjct: 239 TYTLCGTPDYIAPEVVSTKPYNKSIDWWSFGILIYEMLAGYTPFYDSNTMKTYEKILNAE 298
Query: 274 VVYPPFFHPDVVDLLGKLITADLTRRLGNLQSGPDDIKSHPWFAEVIWEKLVAKDIETPY 333
+ +PPFF+ DV DLL +LIT DL++RLGNLQ+G +D+K+HPWF EV+WEKL++++IETPY
Sbjct: 299 LRFPPFFNEDVKDLLSRLITRDLSQRLGNLQNGTEDVKNHPWFKEVVWEKLLSRNIETPY 358
Query: 334 EPPIAVGVGDSSLFDQYPEEQLDYGVQGEDPYGQYFLDF 372
EPPI G GD+S FD+YPEE ++YGVQGEDPY F DF
Sbjct: 359 EPPIQQGQGDTSQFDKYPEEDINYGVQGEDPYADLFRDF 397
>SPBC106.10 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 512
Score = 423 bits (1088), Expect = e-118
Identities = 205/337 (60%), Positives = 248/337 (72%), Gaps = 2/337 (0%)
Query: 37 LLAQQKESLLPQRSTVSKGKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKH 96
LL Q+ + P T +K +Y + DF ++TLGTGSFGRVHLV+S HN YYAIKVL+K
Sbjct: 177 LLDLQRRRIRPADHT-TKDRYGIQDFNFLQTLGTGSFGRVHLVQSNHNRLYYAIKVLEKK 235
Query: 97 QIIRMKQIEHTNDERRMLKLVEHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQR 156
+I+ MKQIEHT DER +L V+HPF+ +WGTFQD++NLFMVMD+ EGGELFSLLRK R
Sbjct: 236 KIVDMKQIEHTCDERYILSRVQHPFITILWGTFQDAKNLFMVMDFAEGGELFSLLRKCHR 295
Query: 157 FPNPVAKFYAAEVTLALEYLHSHNIIYRDLKPENILLDRNGHIKITDFGFAKEVITVT-W 215
FP VAKFYAAEV LAL+YLH + I+YRDLKPEN+LLDR GH+KI DFGFAK V T
Sbjct: 296 FPEKVAKFYAAEVILALDYLHHNQIVYRDLKPENLLLDRFGHLKIVDFGFAKRVSTSNCC 355
Query: 216 TLCGTPDYIAPEVITTKPYNKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVV 275
TLCGTPDY+APE+I+ KPYNK+ DWWSLGILIFEMLAGY PFY PMK YE IL G+V
Sbjct: 356 TLCGTPDYLAPEIISLKPYNKAADWWSLGILIFEMLAGYPPFYSENPMKLYENILEGKVN 415
Query: 276 YPPFFHPDVVDLLGKLITADLTRRLGNLQSGPDDIKSHPWFAEVIWEKLVAKDIETPYEP 335
YP +F P +DLL L+ D+T R GNL+ G DI HPWF ++ W+K++ + IE PY P
Sbjct: 416 YPSYFSPASIDLLSHLLQRDITCRYGNLKDGSMDIIMHPWFRDISWDKILTRKIEVPYVP 475
Query: 336 PIAVGVGDSSLFDQYPEEQLDYGVQGEDPYGQYFLDF 372
PI G+GDSS FD Y + DYG + + F DF
Sbjct: 476 PIQAGMGDSSQFDAYADVATDYGTSEDPEFTSIFKDF 512
>Hs4506055 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 351
Score = 352 bits (904), Expect = 4e-97
Identities = 166/341 (48%), Positives = 243/341 (70%), Gaps = 3/341 (0%)
Query: 32 QSTDYLLAQQKESLLPQRSTVSKGKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIK 91
+S LA+ KE L + + ++ L F+ ++TLGTGSFGRV LV+ G +YA+K
Sbjct: 14 ESVKEFLAKAKEDFLKKWESPAQNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHYAMK 73
Query: 92 VLKKHQIIRMKQIEHTNDERRMLKLVEHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLL 151
+L K +++++KQIEHT +E+R+L+ V PFL+++ +F+D+ NL+MVM+Y+ GGE+FS L
Sbjct: 74 ILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHL 133
Query: 152 RKSQRFPNPVAKFYAAEVTLALEYLHSHNIIYRDLKPENILLDRNGHIKITDFGFAKEVI 211
R+ RF P A+FYAA++ L EYLHS ++IYRDLKPEN+L+D+ G+I++TDFGFAK V
Sbjct: 134 RRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVK 193
Query: 212 TVTWTLCGTPDYIAPEVITTKPYNKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILA 271
TWTLCGTP+Y+APE+I +K YNK+VDWW+LG+LI+EM AGY PF+ P++ YEKI++
Sbjct: 194 GRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVS 253
Query: 272 GEVVYPPFFHPDVVDLLGKLITADLTRRLGNLQSGPDDIKSHPWFAEVIWEKLVAKDIET 331
G+V +P F D+ DLL L+ DLT+R GNL++G +DIK+H WFA W + + +E
Sbjct: 254 GKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEA 313
Query: 332 PYEPPIAVGVGDSSLFDQYPEEQLDYGVQGEDPYGQYFLDF 372
P+ P G GD+S FD Y EE++ + + G+ F +F
Sbjct: 314 PFIPKFK-GPGDTSNFDDYEEEEIRVSI--NEKCGKEFSEF 351
>Hs4506057 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 351
Score = 351 bits (900), Expect = 1e-96
Identities = 165/324 (50%), Positives = 231/324 (70%), Gaps = 1/324 (0%)
Query: 32 QSTDYLLAQQKESLLPQRSTVSKGKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIK 91
+S LA+ KE L + ++ L DF+ +TLGTGSFGRV LV+ +YYA+K
Sbjct: 14 ESVKEFLAKAKEDFLKKWENPTQNNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMK 73
Query: 92 VLKKHQIIRMKQIEHTNDERRMLKLVEHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLL 151
+L K +++++KQIEHT +E+R+L+ V PFL+R+ F+D+ NL+MVM+Y+ GGE+FS L
Sbjct: 74 ILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHL 133
Query: 152 RKSQRFPNPVAKFYAAEVTLALEYLHSHNIIYRDLKPENILLDRNGHIKITDFGFAKEVI 211
R+ RF P A+FYAA++ L EYLHS ++IYRDLKPEN+L+D G+I++TDFGFAK V
Sbjct: 134 RRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVK 193
Query: 212 TVTWTLCGTPDYIAPEVITTKPYNKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILA 271
TWTLCGTP+Y+APE+I +K YNK+VDWW+LG+LI+EM AGY PF+ P++ YEKI++
Sbjct: 194 GRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVS 253
Query: 272 GEVVYPPFFHPDVVDLLGKLITADLTRRLGNLQSGPDDIKSHPWFAEVIWEKLVAKDIET 331
G+V +P F D+ DLL L+ DLT+R GNL++G DIK+H WFA W + + +E
Sbjct: 254 GKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQRKVEA 313
Query: 332 PYEPPIAVGVGDSSLFDQYPEEQL 355
P+ P G GD+S FD Y EE +
Sbjct: 314 PFIPKFR-GSGDTSNFDDYEEEDI 336
>CE15473 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 359
Score = 347 bits (890), Expect = 2e-95
Identities = 166/342 (48%), Positives = 238/342 (69%), Gaps = 3/342 (0%)
Query: 31 SQSTDYLLAQQKESLLPQRSTVSKGKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAI 90
S S L + +E + ++ L DF ++TLGTGSFGRV LV+ +G YYA+
Sbjct: 21 SASLKEFLDKAREDFKQRWENPAQNTACLDDFDRIKTLGTGSFGRVMLVKHKQSGNYYAM 80
Query: 91 KVLKKHQIIRMKQIEHTNDERRMLKLVEHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSL 150
K+L K +++++KQ+EHT +E+R+L+ ++ PFL+ M +F+D+ NL+MV+++I GGE+FS
Sbjct: 81 KILDKQKVVKLKQVEHTLNEKRILQAIDFPFLVNMTFSFKDNSNLYMVLEFISGGEMFSH 140
Query: 151 LRKSQRFPNPVAKFYAAEVTLALEYLHSHNIIYRDLKPENILLDRNGHIKITDFGFAKEV 210
LR+ RF P ++FYAA++ LA EYLHS ++IYRDLKPEN+L+D G++KITDFGFAK V
Sbjct: 141 LRRIGRFSEPHSRFYAAQIVLAFEYLHSLDLIYRDLKPENLLIDSTGYLKITDFGFAKRV 200
Query: 211 ITVTWTLCGTPDYIAPEVITTKPYNKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKIL 270
TWTLCGTP+Y+APE+I +K YNK+VDWW+LG+LI+EM AGY PF+ P++ YEKI+
Sbjct: 201 KGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIV 260
Query: 271 AGEVVYPPFFHPDVVDLLGKLITADLTRRLGNLQSGPDDIKSHPWFAEVIWEKLVAKDIE 330
+G+V +P F ++ DLL L+ DLT+R GNL++G DIK+H WF W + K IE
Sbjct: 261 SGKVKFPSHFSNELKDLLKNLLQVDLTKRYGNLKNGVADIKNHKWFGSTDWIAIYQKKIE 320
Query: 331 TPYEPPIAVGVGDSSLFDQYPEEQLDYGVQGEDPYGQYFLDF 372
P+ P G GD+S FD Y EE L + G + + F +F
Sbjct: 321 APFLPKCR-GPGDASNFDDYEEEPL--RISGTEKCAKEFAEF 359
>Hs4826948 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 358
Score = 341 bits (875), Expect = 9e-94
Identities = 159/300 (53%), Positives = 219/300 (73%), Gaps = 1/300 (0%)
Query: 57 YTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRMLKL 116
Y+L DF + T+GTG+FGRVHLV+ ++A+KV+ +IR+KQ +H ++E+ +LK
Sbjct: 44 YSLQDFDTLATVGTGTFGRVHLVKEKTAKHFFALKVMSIPDVIRLKQEQHVHNEKSVLKE 103
Query: 117 VEHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLALEYL 176
V HPFLIR++ T+ D R L+M+M+Y+ GGELFS LR RF + FY+AE+ A+EYL
Sbjct: 104 VSHPFLIRLFWTWHDERFLYMLMEYVPGGELFSYLRNRGRFSSTTGLFYSAEIICAIEYL 163
Query: 177 HSHNIIYRDLKPENILLDRNGHIKITDFGFAKEVITVTWTLCGTPDYIAPEVITTKPYNK 236
HS I+YRDLKPENILLDR+GHIK+TDFGFAK+++ TWTLCGTP+Y+APEVI +K + +
Sbjct: 164 HSKEIVYRDLKPENILLDRDGHIKLTDFGFAKKLVDRTWTLCGTPEYLAPEVIQSKGHGR 223
Query: 237 SVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFFHPDVVDLLGKLITADL 296
+VDWW+LGILIFEML+G+ PF+D P Y+KILAG++ +P V DL+ KL+ D
Sbjct: 224 AVDWWALGILIFEMLSGFPPFFDDNPFGIYQKILAGKIDFPRHLDFHVKDLIKKLLVVDR 283
Query: 297 TRRLGNLQSGPDDIKSHPWFAEVIWEKLVAKDIETPYEPPIAVGVGDSSLFDQYPEEQLD 356
TRRLGN+++G +D+K H WF V WE + + ++ P P IA G GD+S F+ YPE D
Sbjct: 284 TRRLGNMKNGANDVKHHRWFRSVDWEAVPQRKLKPPIVPKIA-GDGDTSNFETYPENDWD 342
>7297542 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 353
Score = 336 bits (861), Expect = 4e-92
Identities = 159/325 (48%), Positives = 228/325 (69%), Gaps = 1/325 (0%)
Query: 31 SQSTDYLLAQQKESLLPQRSTVSKGKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAI 90
+++ L Q KE + L DF+ ++TLGTGSFGRV +V+ YYA+
Sbjct: 15 AETVKEFLEQAKEEFEDKWRRNPTNTAALDDFERIKTLGTGSFGRVMIVQHKPTKDYYAM 74
Query: 91 KVLKKHQIIRMKQIEHTNDERRMLKLVEHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSL 150
K+L K +++++KQ+EHT +E+R+L+ ++ PFL+ + F+D+ NL+MV++Y+ GGE+FS
Sbjct: 75 KILDKQKVVKLKQVEHTLNEKRILQAIQFPFLVSLRYHFKDNSNLYMVLEYVPGGEMFSH 134
Query: 151 LRKSQRFPNPVAKFYAAEVTLALEYLHSHNIIYRDLKPENILLDRNGHIKITDFGFAKEV 210
LRK RF P ++FYAA++ LA EYLH ++IYRDLKPEN+L+D G++K+TDFGFAK V
Sbjct: 135 LRKVGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYLKVTDFGFAKRV 194
Query: 211 ITVTWTLCGTPDYIAPEVITTKPYNKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKIL 270
TWTLCGTP+Y+APE+I +K YNK+VDWW+LG+L++EM AGY PF+ P++ YEKI+
Sbjct: 195 KGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLVYEMAAGYPPFFADQPIQIYEKIV 254
Query: 271 AGEVVYPPFFHPDVVDLLGKLITADLTRRLGNLQSGPDDIKSHPWFAEVIWEKLVAKDIE 330
+G+V +P F D+ DLL L+ DLT+R GNL++G +DIK+ WFA W + K IE
Sbjct: 255 SGKVRFPSHFGSDLKDLLRNLLQVDLTKRYGNLKAGVNDIKNQKWFASTDWIAIFQKKIE 314
Query: 331 TPYEPPIAVGVGDSSLFDQYPEEQL 355
P+ P G GD+S FD Y EE L
Sbjct: 315 APFIPR-CKGPGDTSNFDDYEEEAL 338
>Hs15619015 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 351
Score = 330 bits (847), Expect = 2e-90
Identities = 155/328 (47%), Positives = 230/328 (69%), Gaps = 1/328 (0%)
Query: 28 TVGSQSTDYLLAQQKESLLPQRSTVSKGKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRY 87
T +S + LA+ + L + ++ + F+ +RTLG GSFGRV LVR G +
Sbjct: 10 TEQEESVNEFLAKARGDFLYRWGNPAQNTASSDQFERLRTLGMGSFGRVMLVRHQETGGH 69
Query: 88 YAIKVLKKHQIIRMKQIEHTNDERRMLKLVEHPFLIRMWGTFQDSRNLFMVMDYIEGGEL 147
YA+K+L K ++++MKQ+EH +E+R+L+ ++ PFL+++ +F+D+ L++VM+Y+ GGE+
Sbjct: 70 YAMKILNKQKVVKMKQVEHILNEKRILQAIDFPFLVKLQFSFKDNSYLYLVMEYVPGGEM 129
Query: 148 FSLLRKSQRFPNPVAKFYAAEVTLALEYLHSHNIIYRDLKPENILLDRNGHIKITDFGFA 207
FS L++ RF P A FYAA+V LA++YLHS ++I+RDLKPEN+L+D+ G++++TDFGFA
Sbjct: 130 FSRLQRVGRFSEPHACFYAAQVVLAVQYLHSLDLIHRDLKPENLLIDQQGYLQVTDFGFA 189
Query: 208 KEVITVTWTLCGTPDYIAPEVITTKPYNKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYE 267
K V TWTLCGTP+Y+APE+I +K YNK+VDWW+LG+LI+EM G+ PFY P++ YE
Sbjct: 190 KRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAVGFPPFYADQPIQIYE 249
Query: 268 KILAGEVVYPPFFHPDVVDLLGKLITADLTRRLGNLQSGPDDIKSHPWFAEVIWEKLVAK 327
KI++G V +P D+ LL L+ DLT+R GNL++G DIK+H WFA W + K
Sbjct: 250 KIVSGRVRFPSKLSSDLKHLLRSLLQVDLTKRFGNLRNGVGDIKNHKWFATTSWIAIYEK 309
Query: 328 DIETPYEPPIAVGVGDSSLFDQYPEEQL 355
+E P+ P G GD+S FD Y EE+L
Sbjct: 310 KVEAPFIPKY-TGPGDASNFDDYEEEEL 336
>CE15475 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 375
Score = 328 bits (842), Expect = 6e-90
Identities = 158/322 (49%), Positives = 227/322 (70%), Gaps = 4/322 (1%)
Query: 31 SQSTDYLLAQQKESLLPQRSTVSKGKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAI 90
S S L + +E + ++ L DF ++TLGTGSFGRV LV+ +G YYA+
Sbjct: 21 SASLKEFLDKAREDFKQRWENPAQNTACLDDFDRIKTLGTGSFGRVMLVKHKQSGNYYAM 80
Query: 91 KVLKKHQIIRMKQIEHTNDERRMLKLVEHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSL 150
K+L K +++++KQ+EHT +E+R+L+ ++ PFL+ M +F+D+ NL+MV+++I GGE+FS
Sbjct: 81 KILDKQKVVKLKQVEHTLNEKRILQAIDFPFLVNMTFSFKDNSNLYMVLEFISGGEMFSH 140
Query: 151 LRKSQRFPNPVAKFYAAEVTLALEYLHSHNIIYRDLKPENILLDRNGHIKITDFGFAKEV 210
LR+ RF P ++FYAA++ LA EYLHS ++IYRDLKPEN+L+D G++KITDFGFAK V
Sbjct: 141 LRRIGRFSEPHSRFYAAQIVLAFEYLHSLDLIYRDLKPENLLIDSTGYLKITDFGFAKRV 200
Query: 211 ITVTWTLCGTPDYIAPEVITTKPYNKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKIL 270
TWTLCGTP+Y+APE+I +K YNK+VDWW+LG+LI+EM AGY PF+ P++ YEKI+
Sbjct: 201 KGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIV 260
Query: 271 AGEVVYPPFFHPDVVDLLGKLITADLTRRLGNLQSGPDDIKSHPWFAEVIWEKLVAKDIE 330
+G+V +P F ++ DLL L+ DLT+R GNL++G DIK+H WF W + K I
Sbjct: 261 SGKVKFPSHFSNELKDLLKNLLQVDLTKRYGNLKNGVADIKNHKWFGSTDWIAIYQKKI- 319
Query: 331 TPYEPPIAVGVGDSSLFDQ-YP 351
TP P + G + LF+ YP
Sbjct: 320 TP--PSFSKGESNGRLFEALYP 339
>CE04603 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 371
Score = 290 bits (742), Expect = 2e-78
Identities = 134/328 (40%), Positives = 216/328 (65%), Gaps = 1/328 (0%)
Query: 26 DVTVGSQSTDYLLAQQKESLLPQRSTVSKGKYTLHDFQIMRTLGTGSFGRVHLVRSVHNG 85
D S+ + + +E+ + T ++ ++L + + T+G G+FGRV L R G
Sbjct: 27 DTNNNSRGNNQVNELAEETHMKLSITPTRESFSLSQLERIITIGKGTFGRVELARDKITG 86
Query: 86 RYYAIKVLKKHQIIRMKQIEHTNDERRMLKLVEHPFLIRMWGTFQDSRNLFMVMDYIEGG 145
+YA+KVL +++ M+Q +H ++E+R+L ++HPF+++M+ + +DS +L+M+M+++ GG
Sbjct: 87 AHYALKVLNIRRVVDMRQTQHVHNEKRVLLQLKHPFIVKMYASEKDSNHLYMIMEFVPGG 146
Query: 146 ELFSLLRKSQRFPNPVAKFYAAEVTLALEYLHSHNIIYRDLKPENILLDRNGHIKITDFG 205
E+FS LR S+ F N +A+FYA+E+ ALEY+HS I+YRDLKPEN++L + GHIK+ DFG
Sbjct: 147 EMFSYLRASRSFSNSMARFYASEIVCALEYIHSLGIVYRDLKPENLMLSKEGHIKMADFG 206
Query: 206 FAKEVITVTWTLCGTPDYIAPEVITTKPYNKSVDWWSLGILIFEMLAGYTPFYDVTPMKT 265
FAKE+ T+T+CGTPDY+APE + +NK VDWW+LGILI+EM+ G PF T +
Sbjct: 207 FAKELRDRTYTICGTPDYLAPESLARTGHNKGVDWWALGILIYEMMVGKPPFRGKTTSEI 266
Query: 266 YEKILAGEVVYPPFFHPDVVDLLGKLITADLTRRLGNLQSGPDDIKSHPWFAEVIWEKLV 325
Y+ I+ ++ +P F+ DL+ KL+ D T+R+G +++G D+K H WF +V W+ +
Sbjct: 267 YDAIIEHKLKFPRSFNLAAKDLVKKLLEVDRTQRIGCMKNGTQDVKDHKWFEKVNWDDTL 326
Query: 326 AKDIETPYEPPIAVGVGDSSLFDQYPEE 353
+E P P + GD+ FD Y E+
Sbjct: 327 HLRVEPPIVPTL-YHPGDTGNFDDYEED 353
>7301971 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 356
Score = 279 bits (713), Expect = 5e-75
Identities = 143/328 (43%), Positives = 211/328 (63%), Gaps = 6/328 (1%)
Query: 31 SQSTDYLLAQQK--ESLLPQRSTVSKGKYT-LHDFQIMRTLGTGSFGRVHLVRSVHNGRY 87
S DY+L K E + +T + T L D++I TLG+GSFG+V LVR +G Y
Sbjct: 13 SPKVDYILILDKLREDFNKKFATNTPSPSTGLDDYEIKATLGSGSFGKVQLVRERESGVY 72
Query: 88 YAIKVLKKHQIIRMKQIEHTNDERRMLKLVEHPFLIRMWGTFQDSRNLFMVMDYIEGGEL 147
YA K L K QI++ KQ+ H E+ +L+ + P + + +++D +L++V+ I GGEL
Sbjct: 73 YASKQLSKDQIVKTKQVSHVMSEKNVLRSMTFPNTVNLIASYKDFDSLYLVLPLIGGGEL 132
Query: 148 FSLLRKSQRFPNPVAKFYAAEVTLALEYLHSHNIIYRDLKPENILLDRNGHIKITDFGFA 207
F+ RK ++F A+FYAA+V LALEYLH +++YRDLKPENI++D+NG++K+TDFGFA
Sbjct: 133 FTYHRKVRKFTEKQARFYAAQVFLALEYLHHCSLLYRDLKPENIMMDKNGYLKVTDFGFA 192
Query: 208 KEVITVTWTLCGTPDYIAPEVITTKPYNKSVDWWSLGILIFEMLAGYTPF--YDVTPMKT 265
K+V T T TLCGTP+Y+ PE+I +KPY SVDWW+ G+L+FE +AG++PF ++ M
Sbjct: 193 KKVETRTMTLCGTPEYLPPEIIQSKPYGTSVDWWAFGVLVFEFVAGHSPFSAHNRDVMSM 252
Query: 266 YEKILAGEVVYPPFFHPDVVDLLGKLITADLTRRLGNLQSGPDDIKSHPWFAEVIWEKLV 325
Y KI + P +F + L+ L+ DL++R GNL +G DIK H WF +V W L+
Sbjct: 253 YNKICEADYKMPSYFSGALRHLVDHLLQVDLSKRFGNLINGNRDIKEHEWFKDVEWIPLL 312
Query: 326 AKDIETPYEPPIAVGVGDSSLFDQYPEE 353
+ + PY P I+ D S FD+ ++
Sbjct: 313 NQTVNAPYVPNIS-NPEDISNFDKVSDK 339
>Hs10835065 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 277
Score = 270 bits (690), Expect = 3e-72
Identities = 123/231 (53%), Positives = 171/231 (73%)
Query: 47 PQRSTVSKGKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEH 106
P+ + Y L D + T+GTG+FGRVHLV+ ++A+KV+ +IR KQ +H
Sbjct: 34 PEARSPEAPAYRLQDCDALVTMGTGTFGRVHLVKEKTAKHFFALKVMSIPDVIRRKQEQH 93
Query: 107 TNDERRMLKLVEHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYA 166
++E+ +LK V HPFLIR++ T+ + R L+M+M+Y+ GGELFS LR F + FY+
Sbjct: 94 VHNEKSVLKEVSHPFLIRLFWTWHEERFLYMLMEYVPGGELFSYLRNRGHFSSTTGLFYS 153
Query: 167 AEVTLALEYLHSHNIIYRDLKPENILLDRNGHIKITDFGFAKEVITVTWTLCGTPDYIAP 226
AE+ A+EYLHS I+YRDLKPENILLDR+GHIK+TDFGFAK+++ TWTLCGTP+Y+AP
Sbjct: 154 AEIICAIEYLHSKEIVYRDLKPENILLDRDGHIKLTDFGFAKKLVDRTWTLCGTPEYLAP 213
Query: 227 EVITTKPYNKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYP 277
EVI +K + ++VDWW+LGILIFEML+G+ PF+D P Y+KILAG++ +P
Sbjct: 214 EVIQSKGHGRAVDWWALGILIFEMLSGFPPFFDDNPFGIYQKILAGKLYFP 264
>CE27166 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 270
Score = 256 bits (653), Expect = 5e-68
Identities = 114/253 (45%), Positives = 177/253 (69%), Gaps = 1/253 (0%)
Query: 101 MKQIEHTNDERRMLKLVEHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNP 160
M+Q +H ++E+R+L ++HPF+++M+ + +DS +L+M+M+++ GGE+FS LR S+ F N
Sbjct: 1 MRQTQHVHNEKRVLLQLKHPFIVKMYASEKDSNHLYMIMEFVPGGEMFSYLRASRSFSNS 60
Query: 161 VAKFYAAEVTLALEYLHSHNIIYRDLKPENILLDRNGHIKITDFGFAKEVITVTWTLCGT 220
+A+FYA+E+ ALEY+HS I+YRDLKPEN++L + GHIK+ DFGFAKE+ T+T+CGT
Sbjct: 61 MARFYASEIVCALEYIHSLGIVYRDLKPENLMLSKEGHIKMADFGFAKELRDRTYTICGT 120
Query: 221 PDYIAPEVITTKPYNKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFF 280
PDY+APE + +NK VDWW+LGILI+EM+ G PF T + Y+ I+ ++ +P F
Sbjct: 121 PDYLAPESLARTGHNKGVDWWALGILIYEMMVGKPPFRGKTTSEIYDAIIEHKLKFPRSF 180
Query: 281 HPDVVDLLGKLITADLTRRLGNLQSGPDDIKSHPWFAEVIWEKLVAKDIETPYEPPIAVG 340
+ DL+ KL+ D T+R+G +++G D+K H WF +V W+ + +E P P +
Sbjct: 181 NLAAKDLVKKLLEVDRTQRIGCMKNGTQDVKDHKWFEKVNWDDTLHLRVEPPIVPTL-YH 239
Query: 341 VGDSSLFDQYPEE 353
GD+ FD Y E+
Sbjct: 240 PGDTGNFDDYEED 252
>CE29092 [T] KOG0694 Serine/threonine protein kinase
Length = 707
Score = 255 bits (652), Expect = 6e-68
Identities = 128/294 (43%), Positives = 189/294 (63%), Gaps = 6/294 (2%)
Query: 50 STVSKGKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTND 109
S V G ++HDF M+ LG GSFG+V L YAIK+LKK I++ +E T
Sbjct: 366 SKVPGGTLSIHDFTFMKVLGKGSFGKVMLAERKGTDEVYAIKILKKDVIVQDDDVECTMC 425
Query: 110 ERRMLKLV-EHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAE 168
E+R+L L +HPFL + +FQ S LF VM+Y+ GG+L ++++++F A+FYAAE
Sbjct: 426 EKRILSLAAKHPFLTALHSSFQTSDRLFFVMEYVNGGDLMFQIQRARKFDESRARFYAAE 485
Query: 169 VTLALEYLHSHNIIYRDLKPENILLDRNGHIKITDFGFAKEVI---TVTWTLCGTPDYIA 225
VT AL++LH +++IYRDLK +NILLD GH ++ DFG KE I +T T CGTPDYIA
Sbjct: 486 VTCALQFLHRNDVIYRDLKLDNILLDAEGHCRLADFGMCKEGINKDNLTSTFCGTPDYIA 545
Query: 226 PEVITTKPYNKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFFHPDVV 285
PE++ Y SVDWW+LG+L++EM+AG PF +E IL +V+YP + + V
Sbjct: 546 PEILQEMEYGVSVDWWALGVLMYEMMAGQPPFEADNEDDLFEAILNDDVLYPVWLSKEAV 605
Query: 286 DLLGKLITADLTRRLGNL--QSGPDDIKSHPWFAEVIWEKLVAKDIETPYEPPI 337
++L +T + +RLG + Q G D I++HP+F E+ W+ L ++ ++ P++P I
Sbjct: 606 NILKAFMTKNAGKRLGCVVSQGGEDAIRAHPFFREIDWDALESRQVKPPFKPKI 659
>Hs4502023 [T] KOG0690 Serine/threonine protein kinase
Length = 481
Score = 254 bits (650), Expect = 1e-67
Identities = 130/326 (39%), Positives = 191/326 (57%), Gaps = 8/326 (2%)
Query: 30 GSQSTDYLLAQQKESLLPQRSTVS----KGKYTLHDFQIMRTLGTGSFGRVHLVRSVHNG 85
G DY +S + V+ + K T++DF ++ LG G+FG+V LVR G
Sbjct: 116 GEDPMDYKCGSPSDSSTTEEMEVAVSKARAKVTMNDFDYLKLLGKGTFGKVILVREKATG 175
Query: 86 RYYAIKVLKKHQIIRMKQIEHTNDERRMLKLVEHPFLIRMWGTFQDSRNLFMVMDYIEGG 145
RYYA+K+L+K II ++ HT E R+L+ HPFL + FQ L VM+Y GG
Sbjct: 176 RYYAMKILRKEVIIAKDEVAHTVTESRVLQNTRHPFLTALKYAFQTHDRLCFVMEYANGG 235
Query: 146 ELFSLLRKSQRFPNPVAKFYAAEVTLALEYLHSHNIIYRDLKPENILLDRNGHIKITDFG 205
ELF L + + F A+FY AE+ ALEYLHS +++YRD+K EN++LD++GHIKITDFG
Sbjct: 236 ELFFHLSRERVFTEERARFYGAEIVSALEYLHSRDVVYRDIKLENLMLDKDGHIKITDFG 295
Query: 206 FAKEVIT---VTWTLCGTPDYIAPEVITTKPYNKSVDWWSLGILIFEMLAGYTPFYDVTP 262
KE I+ T CGTP+Y+APEV+ Y ++VDWW LG++++EM+ G PFY+
Sbjct: 296 LCKEGISDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDH 355
Query: 263 MKTYEKILAGEVVYPPFFHPDVVDLLGKLITADLTRRLGNLQSGPDDIKSHPWFAEVIWE 322
+ +E IL E+ +P P+ LL L+ D +RLG S ++ H +F + W+
Sbjct: 356 ERLFELILMEEIRFPRTLSPEAKSLLAGLLKKDPKQRLGGGPSDAKEVMEHRFFLSINWQ 415
Query: 323 KLVAKDIETPYEPPIAVGVGDSSLFD 348
+V K + P++P + V D+ FD
Sbjct: 416 DVVQKKLLPPFKPQVTSEV-DTRYFD 440
>Hs4885549 [T] KOG0690 Serine/threonine protein kinase
Length = 479
Score = 253 bits (647), Expect = 2e-67
Identities = 131/306 (42%), Positives = 186/306 (59%), Gaps = 10/306 (3%)
Query: 50 STVSKGKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTND 109
ST + T++DF ++ LG G+FG+V LVR +G+YYA+K+LKK II ++ HT
Sbjct: 136 STTHHKRKTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLT 195
Query: 110 ERRMLKLVEHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEV 169
E R+LK HPFL + +FQ L VM+Y+ GGELF L + + F +FY AE+
Sbjct: 196 ESRVLKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEI 255
Query: 170 TLALEYLHSHNIIYRDLKPENILLDRNGHIKITDFGFAKEVIT---VTWTLCGTPDYIAP 226
AL+YLHS I+YRDLK EN++LD++GHIKITDFG KE IT T CGTP+Y+AP
Sbjct: 256 VSALDYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAP 315
Query: 227 EVITTKPYNKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFFHPDVVD 286
EV+ Y ++VDWW LG++++EM+ G PFY+ K +E IL ++ +P D
Sbjct: 316 EVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRTLSSDAKS 375
Query: 287 LLGKLITADLTRRLGNLQSGPDDIKS---HPWFAEVIWEKLVAKDIETPYEPPIAVGVGD 343
LL L+ D +RLG GPDD K H +F+ V W+ + K + P++P + D
Sbjct: 376 LLSGLLIKDPNKRLG---GGPDDAKEIMRHSFFSGVNWQDVYDKKLVPPFKPQV-TSETD 431
Query: 344 SSLFDQ 349
+ FD+
Sbjct: 432 TRYFDE 437
>YKL126w [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 680
Score = 250 bits (639), Expect = 2e-66
Identities = 124/300 (41%), Positives = 191/300 (63%), Gaps = 5/300 (1%)
Query: 58 TLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRMLKLV 117
++ DF +++ +G GSFG+V VR + YA+K ++K I+ ++ HT ER +L V
Sbjct: 343 SIDDFDLLKVIGKGSFGKVMQVRKKDTQKVYALKAIRKSYIVSKSEVTHTLAERTVLARV 402
Query: 118 EHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLALEYLH 177
+ PF++ + +FQ L+ V+ +I GGELF L+K RF A+FY AE+ AL+ LH
Sbjct: 403 DCPFIVPLKFSFQSPEKLYFVLAFINGGELFYHLQKEGRFDLSRARFYTAELLCALDNLH 462
Query: 178 SHNIIYRDLKPENILLDRNGHIKITDFGFAK---EVITVTWTLCGTPDYIAPEVITTKPY 234
+++YRDLKPENILLD GHI + DFG K + T T CGTP+Y+APE++ Y
Sbjct: 463 KLDVVYRDLKPENILLDYQGHIALCDFGLCKLNMKDDDKTDTFCGTPEYLAPELLLGLGY 522
Query: 235 NKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFFHPDVVDLLGKLITA 294
K+VDWW+LG+L++EML G P+YD K Y+KIL +V+P F D DLL L++
Sbjct: 523 TKAVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQEPLVFPDGFDRDAKDLLIGLLSR 582
Query: 295 DLTRRLGNLQSGPDDIKSHPWFAEVIWEKLVAKDIETPYEPPIAVGVGDSSLFDQYPEEQ 354
D TRRLG +G D+I++HP+F+++ W++L+ K PY+P ++ + S+ +++ E+
Sbjct: 583 DPTRRLG--YNGADEIRNHPFFSQLSWKRLLMKGYIPPYKPAVSNSMDTSNFDEEFTREK 640
>Hs5453978 [T] KOG0614 cGMP-dependent protein kinase
Length = 762
Score = 250 bits (639), Expect = 2e-66
Identities = 130/298 (43%), Positives = 193/298 (64%), Gaps = 5/298 (1%)
Query: 61 DFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRMLKLVEHP 120
+ +I+ TLG G FGRV LV+ + +A+K ++K I+ KQ EH E+R+L+ + P
Sbjct: 452 NLEIIATLGVGGFGRVELVKVKNENVAFAMKCIRKKHIVDTKQQEHVYSEKRILEELCSP 511
Query: 121 FLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLALEYLHSHN 180
F+++++ TF+D++ ++M+++ GGEL+S+LR F P +KF A VT A +YLH
Sbjct: 512 FIVKLYRTFKDNKYVYMLLEACLGGELWSILRDRGSFDEPTSKFCVACVTEAFDYLHRLG 571
Query: 181 IIYRDLKPENILLDRNGHIKITDFGFAKEVIT--VTWTLCGTPDYIAPEVITTKPYNKSV 238
IIYRDLKPEN++LD G++K+ DFGFAK++ + TWT CGTP+Y+APEVI K ++ SV
Sbjct: 572 IIYRDLKPENLILDAEGYLKLVDFGFAKKIGSGQKTWTFCGTPEYVAPEVILNKGHDFSV 631
Query: 239 DWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAG--EVVYPPFFHPDVVDLLGKLITADL 296
D+WSLGIL++E+L G PF V M TY IL G ++ +P DL+ +L +
Sbjct: 632 DFWSLGILVYELLTGNPPFSGVDQMMTYNLILKGIEKMDFPRKITRRPEDLIRRLCRQNP 691
Query: 297 TRRLGNLQSGPDDIKSHPWFAEVIWEKLVAKDIETPYEPPIAVGVGDSSLFDQYPEEQ 354
T RLGNL++G +DIK H W WE L A+ + +P + + G D S FD+YP E+
Sbjct: 692 TERLGNLKNGINDIKKHRWLNGFNWEGLKARSLPSPLQRELK-GPIDHSYFDKYPPEK 748
>Hs5453972 [T] KOG0694 Serine/threonine protein kinase
Length = 682
Score = 250 bits (638), Expect = 3e-66
Identities = 130/290 (44%), Positives = 177/290 (60%), Gaps = 5/290 (1%)
Query: 53 SKGKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERR 112
S + + +F+ +R LG GSFG+V L R G YA+KVLKK I+ +E T E+R
Sbjct: 345 SSNRLGIDNFEFIRVLGKGSFGKVMLARVKETGDLYAVKVLKKDVILLDDDVECTMTEKR 404
Query: 113 MLKLVE-HPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTL 171
+L L HPFL +++ FQ LF VM+++ GG+L ++KS+RF A+FYAAE+
Sbjct: 405 ILSLARNHPFLTQLFCCFQTPDRLFFVMEFVNGGDLMFHIQKSRRFDEARARFYAAEIIS 464
Query: 172 ALEYLHSHNIIYRDLKPENILLDRNGHIKITDFGFAKEVI---TVTWTLCGTPDYIAPEV 228
AL +LH IIYRDLK +N+LLD GH K+ DFG KE I T T CGTPDYIAPE+
Sbjct: 465 ALMFLHDKGIIYRDLKLDNVLLDHEGHCKLADFGMCKEGICNGVTTATFCGTPDYIAPEI 524
Query: 229 ITTKPYNKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFFHPDVVDLL 288
+ Y +VDWW++G+L++EML G+ PF +E IL EVVYP + H D +L
Sbjct: 525 LQEMLYGPAVDWWAMGVLLYEMLCGHAPFEAENEDDLFEAILNDEVVYPTWLHEDATGIL 584
Query: 289 GKLITADLTRRLGNL-QSGPDDIKSHPWFAEVIWEKLVAKDIETPYEPPI 337
+T + T RLG+L Q G I HP+F E+ W +L + IE P+ P I
Sbjct: 585 KSFMTKNPTMRLGSLTQGGEHAILRHPFFKEIDWAQLNHRQIEPPFRPRI 634
>Hs10835242 [T] KOG0614 cGMP-dependent protein kinase
Length = 686
Score = 249 bits (637), Expect = 4e-66
Identities = 130/300 (43%), Positives = 187/300 (62%), Gaps = 6/300 (2%)
Query: 59 LHDFQIMRTLGTGSFGRVHLVR-SVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRMLKLV 117
L DF I+ TLG G FGRV LV+ + +A+K+LKK I+ +Q EH E+++++
Sbjct: 372 LSDFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQQEHIRSEKQIMQGA 431
Query: 118 EHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLALEYLH 177
F++R++ TF+DS+ L+M+M+ GGEL+++LR F + +FY A V A YLH
Sbjct: 432 HSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLH 491
Query: 178 SHNIIYRDLKPENILLDRNGHIKITDFGFAKEV--ITVTWTLCGTPDYIAPEVITTKPYN 235
S IIYRDLKPEN++LD G+ K+ DFGFAK++ TWT CGTP+Y+APE+I K ++
Sbjct: 492 SKGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGFGKKTWTFCGTPEYVAPEIILNKGHD 551
Query: 236 KSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAG--EVVYPPFFHPDVVDLLGKLIT 293
S D+WSLGIL++E+L G PF PMKTY IL G + +P + +L+ KL
Sbjct: 552 ISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEFPKKIAKNAANLIKKLCR 611
Query: 294 ADLTRRLGNLQSGPDDIKSHPWFAEVIWEKLVAKDIETPYEPPIAVGVGDSSLFDQYPEE 353
+ + RLGNL++G DI+ H WF WE L + P P +A D+S FD +PE+
Sbjct: 612 DNPSERLGNLKNGVKDIQKHKWFEGFNWEGLRKGTLTPPIIPSVA-SPTDTSNFDSFPED 670
>Hs4885061 [T] KOG0690 Serine/threonine protein kinase
Length = 480
Score = 249 bits (636), Expect = 5e-66
Identities = 124/300 (41%), Positives = 184/300 (61%), Gaps = 5/300 (1%)
Query: 54 KGKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRM 113
K + T+++F+ ++ LG G+FG+V LV+ GRYYA+K+LKK I+ ++ HT E R+
Sbjct: 142 KHRVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTENRV 201
Query: 114 LKLVEHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLAL 173
L+ HPFL + +FQ L VM+Y GGELF L + + F A+FY AE+ AL
Sbjct: 202 LQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVSAL 261
Query: 174 EYLHSH-NIIYRDLKPENILLDRNGHIKITDFGFAKEVI---TVTWTLCGTPDYIAPEVI 229
+YLHS N++YRDLK EN++LD++GHIKITDFG KE I T CGTP+Y+APEV+
Sbjct: 262 DYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGIKDGATMKTFCGTPEYLAPEVL 321
Query: 230 TTKPYNKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFFHPDVVDLLG 289
Y ++VDWW LG++++EM+ G PFY+ K +E IL E+ +P P+ LL
Sbjct: 322 EDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPRTLGPEAKSLLS 381
Query: 290 KLITADLTRRLGNLQSGPDDIKSHPWFAEVIWEKLVAKDIETPYEPPIAVGVGDSSLFDQ 349
L+ D +RLG +I H +FA ++W+ + K + P++P + D+ FD+
Sbjct: 382 GLLKKDPKQRLGGGSEDAKEIMQHRFFAGIVWQHVYEKKLSPPFKPQV-TSETDTRYFDE 440
>Hs4506737 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 525
Score = 249 bits (635), Expect = 6e-66
Identities = 132/322 (40%), Positives = 194/322 (59%), Gaps = 12/322 (3%)
Query: 62 FQIMRTLGTGSFGRVHLVRSV---HNGRYYAIKVLKKHQIIR-MKQIEHTNDERRMLKLV 117
F+++R LG G +G+V VR V + G+ +A+KVLKK I+R K HT ER +L+ V
Sbjct: 91 FELLRVLGKGGYGKVFQVRKVTGANTGKIFAMKVLKKAMIVRNAKDTAHTKAERNILEEV 150
Query: 118 EHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLALEYLH 177
+HPF++ + FQ L+++++Y+ GGELF L + F A FY AE+++AL +LH
Sbjct: 151 KHPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLEREGIFMEDTACFYLAEISMALGHLH 210
Query: 178 SHNIIYRDLKPENILLDRNGHIKITDFGFAKEVI---TVTWTLCGTPDYIAPEVITTKPY 234
IIYRDLKPENI+L+ GH+K+TDFG KE I TVT T CGT +Y+APE++ +
Sbjct: 211 QKGIIYRDLKPENIMLNHQGHVKLTDFGLCKESIHDGTVTHTFCGTIEYMAPEILMRSGH 270
Query: 235 NKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFFHPDVVDLLGKLITA 294
N++VDWWSLG L+++ML G PF KT +KIL ++ PP+ + DLL KL+
Sbjct: 271 NRAVDWWSLGALMYDMLTGAPPFTGENRKKTIDKILKCKLNLPPYLTQEARDLLKKLLKR 330
Query: 295 DLTRRLGNLQSGPDDIKSHPWFAEVIWEKLVAKDIETPYEPPIA----VGVGDSSLFDQY 350
+ RLG ++++HP+F + WE+L+A+ +E P++P + V DS Q
Sbjct: 331 NAASRLGAGPGDAGEVQAHPFFRHINWEELLARKVEPPFKPLLQSEEDVSQFDSKFTRQT 390
Query: 351 PEEQLDYGVQGEDPYGQYFLDF 372
P + D E Q FL F
Sbjct: 391 PVDSPDDSTLSESA-NQVFLGF 411
>CE15612 [T] KOG0690 Serine/threonine protein kinase
Length = 541
Score = 248 bits (634), Expect = 8e-66
Identities = 131/311 (42%), Positives = 186/311 (59%), Gaps = 10/311 (3%)
Query: 44 SLLPQRSTVSKGKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQ 103
S+ + K T+ DF ++ LG G+FG+V L + + YAIK+LKK II ++
Sbjct: 175 SIADTSEAAKRDKITMEDFDFLKVLGKGTFGKVILCKEKRTQKLYAIKILKKDVIIAREE 234
Query: 104 IEHTNDERRMLKLVEHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAK 163
+ HT E R+L+ +HPFL + +FQ+ L VM + GGELF+ +RK F P A+
Sbjct: 235 VAHTLTENRVLQRCKHPFLTELKYSFQEQHYLCFVMQFANGGELFTHVRKCGTFSEPRAR 294
Query: 164 FYAAEVTLALEYLHSHNIIYRDLKPENILLDRNGHIKITDFGFAKEVITV---TWTLCGT 220
FY AE+ LAL YLH +I+YRD+K EN+LLD++GHIKI DFG KE I+ T T CGT
Sbjct: 295 FYGAEIVLALGYLHRCDIVYRDMKLENLLLDKDGHIKIADFGLCKEEISFGDKTSTFCGT 354
Query: 221 PDYIAPEVITTKPYNKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFF 280
P+Y+APEV+ Y + VDWW +G++++EM+ G PFY K +E I+AG++ +P
Sbjct: 355 PEYLAPEVLDDHDYGRCVDWWGVGVVMYEMMCGRLPFYSKDHNKLFELIMAGDLRFPSKL 414
Query: 281 HPDVVDLLGKLITADLTRRLGNLQSGPDD---IKSHPWFAEVIWEKLVAKDIETPYEPPI 337
+ LL L+ D T+RLG GP+D I +F V WE K+IE PY+P +
Sbjct: 415 SQEARTLLTGLLVKDPTQRLG---GGPEDALEICRADFFRTVDWEATYRKEIEPPYKPNV 471
Query: 338 AVGVGDSSLFD 348
D+S FD
Sbjct: 472 Q-SETDTSYFD 481
>7301734 [T] KOG0694 Serine/threonine protein kinase
Length = 739
Score = 248 bits (634), Expect = 8e-66
Identities = 126/285 (44%), Positives = 183/285 (64%), Gaps = 5/285 (1%)
Query: 55 GKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRML 114
GK +L DF ++ LG GSFG+V L YAIKVLKK II+ ++ T E+R+L
Sbjct: 401 GKCSLLDFNFIKVLGKGSFGKVMLAEKKGTDEIYAIKVLKKDAIIQDDDVDCTMTEKRIL 460
Query: 115 KLV-EHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLAL 173
L HPFL + FQ LF VM+Y+ GG+L ++K++RF A FYAAEVTLAL
Sbjct: 461 ALAANHPFLTALHSCFQTPDRLFFVMEYVNGGDLMFQIQKARRFEASRAAFYAAEVTLAL 520
Query: 174 EYLHSHNIIYRDLKPENILLDRNGHIKITDFGFAKEVI---TVTWTLCGTPDYIAPEVIT 230
++LH+H +IYRDLK +NILLD+ GH K+ DFG KE I +T T CGTPDYIAPE++
Sbjct: 521 QFLHTHGVIYRDLKLDNILLDQEGHCKLADFGMCKEGIMNGMLTTTFCGTPDYIAPEILK 580
Query: 231 TKPYNKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFFHPDVVDLLGK 290
+ Y SVDWW+LG+L++EM+AG PF + ++ I+ +V+YP + + V +L
Sbjct: 581 EQEYGASVDWWALGVLMYEMMAGQPPFEADNEDELFDSIMHDDVLYPVWLSREAVSILKG 640
Query: 291 LITADLTRRLGNLQSGPDDIKSHPWFAEVIWEKLVAKDIETPYEP 335
+T + +RLG ++I+ HP+FA++ W++L ++I+ P+ P
Sbjct: 641 FLTKNPEQRLG-CTGDENEIRKHPFFAKLDWKELEKRNIKPPFRP 684
>Hs4506739 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 495
Score = 248 bits (633), Expect = 1e-65
Identities = 122/283 (43%), Positives = 180/283 (63%), Gaps = 7/283 (2%)
Query: 60 HDFQIMRTLGTGSFGRVHLVRSVHN---GRYYAIKVLKKHQIIR-MKQIEHTNDERRMLK 115
H F+++R LG G +G+V VR V G+ YA+KVL+K +I+R K HT ER +L+
Sbjct: 78 HCFELLRVLGKGGYGKVFQVRKVQGTNLGKIYAMKVLRKAKIVRNAKDTAHTRAERNILE 137
Query: 116 LVEHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLALEY 175
V+HPF++ + FQ L+++++ + GGELF+ L + F A FY AE+TLAL +
Sbjct: 138 SVKHPFIVELAYAFQTGGKLYLILECLSGGELFTHLEREGIFLEDTACFYLAEITLALGH 197
Query: 176 LHSHNIIYRDLKPENILLDRNGHIKITDFGFAKEVI---TVTWTLCGTPDYIAPEVITTK 232
LHS IIYRDLKPENI+L GHIK+TDFG KE I VT T CGT +Y+APE++
Sbjct: 198 LHSQGIIYRDLKPENIMLSSQGHIKLTDFGLCKESIHEGAVTHTFCGTIEYMAPEILVRS 257
Query: 233 PYNKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFFHPDVVDLLGKLI 292
+N++VDWWSLG L+++ML G PF KT +KI+ G++ PP+ PD DL+ K +
Sbjct: 258 GHNRAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIRGKLALPPYLTPDARDLVKKFL 317
Query: 293 TADLTRRLGNLQSGPDDIKSHPWFAEVIWEKLVAKDIETPYEP 335
+ ++R+G D++ HP+F + W+ L+A ++ P+ P
Sbjct: 318 KRNPSQRIGGGPGDAADVQRHPFFRHMNWDDLLAWRVDPPFRP 360
>7300106 [T] KOG0690 Serine/threonine protein kinase
Length = 530
Score = 248 bits (632), Expect = 1e-65
Identities = 128/297 (43%), Positives = 179/297 (60%), Gaps = 4/297 (1%)
Query: 56 KYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRMLK 115
K TL +F+ ++ LG G+FG+V L R + YAIK+LKK II+ ++ HT E R+LK
Sbjct: 179 KVTLENFEFLKVLGKGTFGKVILCREKATAKLYAIKILKKEVIIQKDEVAHTLTESRVLK 238
Query: 116 LVEHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLALEY 175
HPFLI + +FQ + L VM Y+ GGELF L + F +FY AE+ AL Y
Sbjct: 239 STNHPFLISLKYSFQTNDRLCFVMQYVNGGELFWHLSHERIFTEDRTRFYGAEIISALGY 298
Query: 176 LHSHNIIYRDLKPENILLDRNGHIKITDFGFAKEVIT---VTWTLCGTPDYIAPEVITTK 232
LHS IIYRDLK EN+LLD++GHIK+ DFG KE IT T T CGTP+Y+APEV+
Sbjct: 299 LHSQGIIYRDLKLENLLLDKDGHIKVADFGLCKEDITYGRTTKTFCGTPEYLAPEVLDDN 358
Query: 233 PYNKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFFHPDVVDLLGKLI 292
Y ++VDWW G++++EM+ G PFY+ + IL EV +P + +LL L+
Sbjct: 359 DYGQAVDWWGTGVVMYEMICGRLPFYNRDHDVLFTLILVEEVKFPRNITDEAKNLLAGLL 418
Query: 293 TADLTRRLGNLQSGPDDIKSHPWFAEVIWEKLVAKDIETPYEPPIAVGVGDSSLFDQ 349
D +RLG + +I++HP+FA + W LV K I P++P + D+ FD+
Sbjct: 419 AKDPKKRLGGGKDDVKEIQAHPFFASINWTDLVLKKIPPPFKPQVTSDT-DTRYFDK 474
>Hs5032091 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 431
Score = 247 bits (630), Expect = 2e-65
Identities = 135/309 (43%), Positives = 193/309 (61%), Gaps = 8/309 (2%)
Query: 61 DFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERR-MLKLVEH 119
DF ++ +G GSFG+V L R +YA+KVL+K I++ K+ +H ER +LK V+H
Sbjct: 97 DFHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKH 156
Query: 120 PFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLALEYLHSH 179
PFL+ + +FQ + L+ V+DYI GGELF L++ + F P A+FYAAE+ AL YLHS
Sbjct: 157 PFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSL 216
Query: 180 NIIYRDLKPENILLDRNGHIKITDFGFAKEVI---TVTWTLCGTPDYIAPEVITTKPYNK 236
NI+YRDLKPENILLD GHI +TDFG KE I + T T CGTP+Y+APEV+ +PY++
Sbjct: 217 NIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNSTTSTFCGTPEYLAPEVLHKQPYDR 276
Query: 237 SVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFFHPDVVDLLGKLITADL 296
+VDWW LG +++EML G PFY + Y+ IL + P LL L+ D
Sbjct: 277 TVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSARHLLEGLLQKDR 336
Query: 297 TRRLGNLQSGPDDIKSHPWFAEVIWEKLVAKDIETPYEPPIAVGVGDSSLFD-QYPEEQL 355
T+RLG + +IKSH +F+ + W+ L+ K I P+ P ++ G + FD ++ EE +
Sbjct: 337 TKRLG-AKDDFMEIKSHVFFSLINWDDLINKKITPPFNPNVS-GPNELRHFDPEFTEEPV 394
Query: 356 DYGVQGEDP 364
+ G+ P
Sbjct: 395 PNSI-GKSP 402
>Hs4885563 [T] KOG0694 Serine/threonine protein kinase
Length = 737
Score = 247 bits (630), Expect = 2e-65
Identities = 130/297 (43%), Positives = 184/297 (61%), Gaps = 7/297 (2%)
Query: 59 LHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRMLKLV- 117
L +F ++ LG GSFG+V L YA+KVLKK I++ ++ T E+R+L L
Sbjct: 405 LDEFNFIKVLGKGSFGKVMLAELKGKDEVYAVKVLKKDVILQDDDVDCTMTEKRILALAR 464
Query: 118 EHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLALEYLH 177
+HP+L +++ FQ LF VM+Y+ GG+L +++S++F P ++FYAAEVT AL +LH
Sbjct: 465 KHPYLTQLYCCFQTKDRLFFVMEYVNGGDLMFQIQRSRKFDEPRSRFYAAEVTSALMFLH 524
Query: 178 SHNIIYRDLKPENILLDRNGHIKITDFGFAKEVI---TVTWTLCGTPDYIAPEVITTKPY 234
H +IYRDLK +NILLD GH K+ DFG KE I T T CGTPDYIAPE++ Y
Sbjct: 525 QHGVIYRDLKLDNILLDAEGHCKLADFGMCKEGILNGVTTTTFCGTPDYIAPEILQELEY 584
Query: 235 NKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFFHPDVVDLLGKLITA 294
SVDWW+LG+L++EM+AG PF +E IL +V+YP + + V +L +T
Sbjct: 585 GPSVDWWALGVLMYEMMAGQPPFEADNEDDLFESILHDDVLYPVWLSKEAVSILKAFMTK 644
Query: 295 DLTRRLGNL--QSGPDDIKSHPWFAEVIWEKLVAKDIETPYEPPIAVGVGDSSLFDQ 349
+ +RLG + Q+G D IK HP+F E+ W L K I+ P++P I D + FDQ
Sbjct: 645 NPHKRLGCVASQNGEDAIKQHPFFKEIDWVLLEQKKIKPPFKPRIKT-KRDVNNFDQ 700
>CE14798 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 422
Score = 246 bits (628), Expect = 4e-65
Identities = 122/303 (40%), Positives = 191/303 (62%), Gaps = 5/303 (1%)
Query: 58 TLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRML-KL 116
T +DF + T+G GSFGRV+ VR + YA+K+L K I + +++H ER +L
Sbjct: 90 TANDFDYLTTIGKGSFGRVYQVRHKETKKIYAMKILSKEHIRKKNEVKHVMAERNVLINN 149
Query: 117 VEHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLALEYL 176
+HPFL+ + +FQ+ L+ V+D++ GGELFS L++ + F ++FYAAE+ AL YL
Sbjct: 150 FKHPFLVSLHFSFQNKEKLYFVLDHLNGGELFSHLQREKHFSESRSRFYAAEIACALGYL 209
Query: 177 HSHNIIYRDLKPENILLDRNGHIKITDFGFAKEVI---TVTWTLCGTPDYIAPEVITTKP 233
H NIIYRDLKPEN+LLD G++ +TDFG KE + T T CGTP+Y+APE+I KP
Sbjct: 210 HEKNIIYRDLKPENLLLDDKGYLVLTDFGLCKEDMQGSKTTSTFCGTPEYLAPEIILKKP 269
Query: 234 YNKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFFHPDVVDLLGKLIT 293
Y+K+VDWW LG +++EM+ G PFY + Y+KI+ + +L+ L+
Sbjct: 270 YDKTVDWWCLGSVLYEMIFGLPPFYSKDHNEMYDKIINQPLRLKHNISVPCSELITGLLQ 329
Query: 294 ADLTRRLGNLQSGPDDIKSHPWFAEVIWEKLVAKDIETPYEPPIAVGVGDSSLFDQYPEE 353
D ++RLG+ ++ DI+ HP+F V W+KL+ ++++ P+ P + + S++ ++ E
Sbjct: 330 KDRSKRLGH-RNDFRDIRDHPFFLPVDWDKLLNRELKAPFIPKVKNAMDTSNISKEFVEI 388
Query: 354 QLD 356
Q+D
Sbjct: 389 QID 391
>SPCC24B10.07 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 569
Score = 246 bits (627), Expect = 5e-65
Identities = 123/299 (41%), Positives = 183/299 (61%), Gaps = 5/299 (1%)
Query: 58 TLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRMLKLV 117
T+ F++++ +G GSFG+V VR R YA+K +KK I+ +++HT ER +L V
Sbjct: 226 TIDAFELLKVVGKGSFGKVMQVRKRDTSRIYALKTMKKAHIVSRSEVDHTLAERTVLAQV 285
Query: 118 EHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLALEYLH 177
+PF++ + +FQ L++V+ ++ GGELF L++ F AKFY AE+ +ALE LH
Sbjct: 286 NNPFIVPLKFSFQSPGKLYLVLAFVNGGELFHHLQREGCFDTYRAKFYIAELLVALECLH 345
Query: 178 SHNIIYRDLKPENILLDRNGHIKITDFGFAKEVITV---TWTLCGTPDYIAPEVITTKPY 234
N+IYRDLKPENILLD GHI + DFG K + T T CGTP+Y+APE++ Y
Sbjct: 346 EFNVIYRDLKPENILLDYTGHIALCDFGLCKLNMAKTDRTNTFCGTPEYLAPELLLGHGY 405
Query: 235 NKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFFHPDVVDLLGKLITA 294
K VDWW+LG+L++EM+ G PFYD + Y KIL + +P DLL L+T
Sbjct: 406 TKVVDWWTLGVLLYEMITGLPPFYDENINEMYRKILQDPLRFPDNIDEKAKDLLSGLLTR 465
Query: 295 DLTRRLGNLQSGPDDIKSHPWFAEVIWEKLVAKDIETPYEPPIAVGVGDSSLFDQYPEE 353
+RLG+ G +IK+HP+F ++ W+KL AK I+ P++P + + S+ ++ E
Sbjct: 466 APEKRLGS--GGAQEIKNHPFFDDIDWKKLCAKKIQPPFKPSVESAIDTSNFDSEFTSE 522
>Hs5453976 [T] KOG0694 Serine/threonine protein kinase
Length = 706
Score = 244 bits (624), Expect = 1e-64
Identities = 130/298 (43%), Positives = 179/298 (59%), Gaps = 9/298 (3%)
Query: 56 KYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRMLK 115
K + DF + + LG GSFG+V L +++AIK LKK ++ +E T E+R+L
Sbjct: 374 KLKIEDFILHKMLGKGSFGKVFLAEFKKTNQFFAIKALKKDVVLMDDDVECTMVEKRVLS 433
Query: 116 LV-EHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLALE 174
L EHPFL M+ TFQ NLF VM+Y+ GG+L ++ +F A FYAAE+ L L+
Sbjct: 434 LAWEHPFLTHMFCTFQTKENLFFVMEYLNGGDLMYHIQSCHKFDLSRATFYAAEIILGLQ 493
Query: 175 YLHSHNIIYRDLKPENILLDRNGHIKITDFGFAKEVI---TVTWTLCGTPDYIAPEVITT 231
+LHS I+YRDLK +NILLD++GHIKI DFG KE + T T CGTPDYIAPE++
Sbjct: 494 FLHSKGIVYRDLKLDNILLDKDGHIKIADFGMCKENMLGDAKTNTFCGTPDYIAPEILLG 553
Query: 232 KPYNKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFFHPDVVDLLGKL 291
+ YN SVDWWS G+L++EML G +PF+ + + I YP + + DLL KL
Sbjct: 554 QKYNHSVDWWSFGVLLYEMLIGQSPFHGQDEEELFHSIRMDNPFYPRWLEKEAKDLLVKL 613
Query: 292 ITADLTRRLGNLQSGPDDIKSHPWFAEVIWEKLVAKDIETPYEPPIAVGVGDSSLFDQ 349
+ +RLG DI+ HP F E+ WE+L K+I+ P+ P + D S FD+
Sbjct: 614 FVREPEKRLG----VRGDIRQHPLFREINWEELERKEIDPPFRPKVK-SPFDCSNFDK 666
>Hs20127541 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 427
Score = 244 bits (623), Expect = 1e-64
Identities = 128/292 (43%), Positives = 183/292 (61%), Gaps = 6/292 (2%)
Query: 61 DFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERR-MLKLVEH 119
DF ++ +G G++G+V L + +G +YA+KVL+K I++ K+ H ER +LK V H
Sbjct: 94 DFDFLKVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKSILKKKEQSHIMAERSVLLKNVRH 153
Query: 120 PFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLALEYLHSH 179
PFL+ + +FQ L+ V+DY+ GGELF L++ +RF P A+FYAAEV A+ YLHS
Sbjct: 154 PFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQRERRFLEPRARFYAAEVASAIGYLHSL 213
Query: 180 NIIYRDLKPENILLDRNGHIKITDFGFAKEVI---TVTWTLCGTPDYIAPEVITTKPYNK 236
NIIYRDLKPENILLD GH+ +TDFG KE + T T CGTP+Y+APEV+ +PY++
Sbjct: 214 NIIYRDLKPENILLDCQGHVVLTDFGLCKEGVEPEDTTSTFCGTPEYLAPEVLRKEPYDR 273
Query: 237 SVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFFHPDVVDLLGKLITADL 296
+VDWW LG +++EML G PFY + YE IL + P DLL L+ D
Sbjct: 274 AVDWWCLGAVLYEMLHGLPPFYSQDVSQMYENILHQPLQIPGGRTVAACDLLQSLLHKDQ 333
Query: 297 TRRLGNLQSGPDDIKSHPWFAEVIWEKLVAKDIETPYEPPIAVGVGDSSLFD 348
+RLG+ ++ +IK+H +F+ + W+ L K + P+ P + G D FD
Sbjct: 334 RQRLGS-KADFLEIKNHVFFSPINWDDLYHKRLTPPFNPNV-TGPADLKHFD 383
>CE03979 [T] KOG0614 cGMP-dependent protein kinase
Length = 581
Score = 244 bits (623), Expect = 1e-64
Identities = 137/327 (41%), Positives = 195/327 (58%), Gaps = 11/327 (3%)
Query: 50 STVSKGKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTND 109
ST+ + L D Q + TLG G FGRV LVRS + R YA+K++ K I+ KQ H
Sbjct: 262 STIEEADVELEDLQRVSTLGMGGFGRVELVRSA-SSRTYALKIMNKAHIVETKQESHVVS 320
Query: 110 ERRMLKLVEHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEV 169
ERR+L ++ +++RM+ T++DS ++M+M+ GGE++++LRK RF N + +FY A
Sbjct: 321 ERRILMQCDNDYIVRMYKTYRDSEKIYMLMEPCLGGEIWTILRKKGRFDNDLTRFYCAGA 380
Query: 170 TLALEYLHSHNIIYRDLKPENILLDRNGHIKITDFGFAKEVIT--VTWTLCGTPDYIAPE 227
ALEYLH NI+YRDLKPEN+LLDRNG K+ DFGFAK++ TWT CGT +Y+APE
Sbjct: 381 MEALEYLHRKNIVYRDLKPENMLLDRNGWPKLVDFGFAKKLKNGGRTWTFCGTAEYVAPE 440
Query: 228 VITTKPYNKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAG--EVVYPPFFHPDVV 285
++ K ++ SVD W+LGI + E+L G PF PM TY IL G + +P F + +
Sbjct: 441 IVLNKGHDLSVDIWALGIFMCELLTGSPPFSSTDPMVTYNAILKGLEKWAWPRFVTKEAI 500
Query: 286 DLLGKLITADLTRRLGNLQSGPDDIKSHPWFAEVIWEKLVAKDIETPYEPPIAVGVGDSS 345
D++ L + T RLG G +I+ H WF + A I P+ P +A + D+S
Sbjct: 501 DMMLSLCKYEPTERLGFGDIG--EIRHHIWFDNFDFVGFRAHRIRPPFIPSVANDI-DTS 557
Query: 346 LFDQYPEEQLDYGVQGEDPYGQYFLDF 372
FD +P D G D G + +DF
Sbjct: 558 NFDTFP--AFDNFASGSDESG-WDIDF 581
>YMR104c [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 677
Score = 243 bits (620), Expect = 3e-64
Identities = 127/301 (42%), Positives = 191/301 (63%), Gaps = 7/301 (2%)
Query: 53 SKGK-YTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDER 111
SK K ++ DF +++ +G GSFG+V VR + YA+K L+K I+ ++ HT ER
Sbjct: 334 SKNKPLSIDDFDLLKVIGKGSFGKVMQVRKKDTQKIYALKALRKAYIVSKCEVTHTLAER 393
Query: 112 RMLKLVEHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTL 171
+L V+ PF++ + +FQ L++V+ +I GGELF L+ RF ++FY AE+
Sbjct: 394 TVLARVDCPFIVPLKFSFQSPEKLYLVLAFINGGELFYHLQHEGRFSLARSRFYIAELLC 453
Query: 172 ALEYLHSHNIIYRDLKPENILLDRNGHIKITDFGFAK---EVITVTWTLCGTPDYIAPEV 228
AL+ LH ++IYRDLKPENILLD GHI + DFG K + T T CGTP+Y+APE+
Sbjct: 454 ALDSLHKLDVIYRDLKPENILLDYQGHIALCDFGLCKLNMKDNDKTDTFCGTPEYLAPEI 513
Query: 229 ITTKPYNKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFFHPDVVDLL 288
+ + Y K+VDWW+LGIL++EM+ G P+YD Y+KIL +++P F P DLL
Sbjct: 514 LLGQGYTKTVDWWTLGILLYEMMTGLPPYYDENVPVMYKKILQQPLLFPDGFDPAAKDLL 573
Query: 289 GKLITADLTRRLGNLQSGPDDIKSHPWFAEVIWEKLVAKDIETPYEPPIAVGVGDSSLFD 348
L++ D +RRLG +G D+I++HP+F ++ W+KL+ K PY+P + + D++ FD
Sbjct: 574 IGLLSRDPSRRLG--VNGTDEIRNHPFFKDISWKKLLLKGYIPPYKPIVKSEI-DTANFD 630
Query: 349 Q 349
Q
Sbjct: 631 Q 631
>CE22045 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 580
Score = 243 bits (619), Expect = 4e-64
Identities = 128/295 (43%), Positives = 181/295 (60%), Gaps = 8/295 (2%)
Query: 61 DFQIMRTLGTGSFGRVHLVRSV---HNGRYYAIKVLKKHQIIR-MKQIEHTNDERRMLKL 116
DFQ+++ LG G +G+V VR NG+ +A+KVL+K I+R K HT ER +L+
Sbjct: 82 DFQLLKVLGKGGYGKVFQVRKTTGSDNGQIFAMKVLQKATIVRNQKDTAHTKAERNILEA 141
Query: 117 VEHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLALEYL 176
V+ PF+ + FQ L+++++Y+ GGELF L + F VAKFY +E+ ++LE+L
Sbjct: 142 VKSPFICDLLYAFQTGGKLYLILEYLSGGELFMHLEREGMFMENVAKFYLSEIVVSLEHL 201
Query: 177 HSHNIIYRDLKPENILLDRNGHIKITDFGFAKEVI---TVTWTLCGTPDYIAPEVITTKP 233
H IIYRDLKPENILLD GH+K+TDFG KE I T T CGT +Y+APE++
Sbjct: 202 HQQGIIYRDLKPENILLDAYGHVKLTDFGLCKEEIEGDQKTHTFCGTIEYMAPEILMRCG 261
Query: 234 YNKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFFHPDVVDLLGKLIT 293
+ K+VDWWSLG L+F+ML G PF KT +KIL G + P + + DL+ KL+
Sbjct: 262 HGKAVDWWSLGALMFDMLTGGPPFTAENRRKTIDKILKGRLTLPAYLSNEARDLIKKLLK 321
Query: 294 ADLTRRLGNLQSGPDDIKSHPWFAEVIWEKLVAKDIETPYEPPIAVGVGDSSLFD 348
+ RLG S ++IKSH +F W + A+ +E P++P I D+SLFD
Sbjct: 322 RHVDTRLGAGLSDAEEIKSHAFFKTTDWNLVYARQLEAPFKPNIE-NDEDTSLFD 375
>Hs20070247_2 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 378
Score = 242 bits (617), Expect = 7e-64
Identities = 130/304 (42%), Positives = 187/304 (60%), Gaps = 7/304 (2%)
Query: 61 DFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERR-MLKLVEH 119
DF ++ +G GSFG+V L + +G+ YA+KVL+K ++ K+ +H ER +LK V+H
Sbjct: 43 DFDFLKVIGKGSFGKVLLAKRKLDGKVYAVKVLQKKIVLNRKEQKHIMAERNVLLKNVKH 102
Query: 120 PFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLALEYLHSH 179
PFL+ + +FQ + L+ V+D++ GGELF L++ + FP A+FYAAE+ AL YLHS
Sbjct: 103 PFLVGLHYSFQTTEKLYFVLDFVNGGELFFHLQRERSFPEHRARFYAAEIASALGYLHSI 162
Query: 180 NIIYRDLKPENILLDRNGHIKITDFGFAKEVITV---TWTLCGTPDYIAPEVITTKPYNK 236
I+YRDLKPENIL+D GH+ +TDFG KE I + T T CGTP+Y+APEVI +PY+
Sbjct: 163 KIVYRDLKPENILVDSVGHVVLTDFGLCKEGIAISDTTTTFCGTPEYLAPEVIRKQPYDN 222
Query: 237 SVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFFHPDVVDLLGKLITADL 296
+VDWW LG +++EML G PFY + Y+ IL + P +L +L+ D
Sbjct: 223 TVDWWCLGAVLYEMLYGLPPFYCRDVAEMYDNILHKPLSLRPGVSLRAWSILEELLEKDR 282
Query: 297 TRRLGNLQSGPDDIKSHPWFAEVIWEKLVAKDIETPYEPPIAVGVGDSSLFD-QYPEEQL 355
RLG + +I++HP+F + W LV K I P+ P +A G D FD + EE +
Sbjct: 283 QNRLGAKEDFL-EIQNHPFFESLSWADLVQKKIPPPFNPNVA-GPDDIRNFDTAFTEETV 340
Query: 356 DYGV 359
Y V
Sbjct: 341 PYSV 344
>7302860 [T] KOG0696 Serine/threonine protein kinase
Length = 679
Score = 240 bits (613), Expect = 2e-63
Identities = 124/300 (41%), Positives = 178/300 (59%), Gaps = 4/300 (1%)
Query: 61 DFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRMLKLVEHP 120
DF ++ LG GSFG+V L + YAIK+LKK II+ +E T E+R+L L E P
Sbjct: 349 DFNFIKVLGKGSFGKVLLAERKGSEELYAIKILKKDVIIQDDDVECTMIEKRVLALGEKP 408
Query: 121 -FLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLALEYLHSH 179
FL+++ FQ LF VM+Y+ GG+L +++ +F PVA FYAAE+ L +LH+
Sbjct: 409 PFLVQLHSCFQTMDRLFFVMEYVNGGDLMFQIQQFGKFKEPVAVFYAAEIAAGLFFLHTK 468
Query: 180 NIIYRDLKPENILLDRNGHIKITDFGFAKEVIT---VTWTLCGTPDYIAPEVITTKPYNK 236
I+YRDLK +N+LLD +GH+KI DFG KE I T T CGTPDYIAPE+I +PY K
Sbjct: 469 GILYRDLKLDNVLLDADGHVKIADFGMCKENIVGDKTTKTFCGTPDYIAPEIILYQPYGK 528
Query: 237 SVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFFHPDVVDLLGKLITADL 296
SVDWW+ G+L++EML G PF + + I V YP + + +T
Sbjct: 529 SVDWWAYGVLLYEMLVGQPPFDGEDEEELFAAITDHNVSYPKSLSKEAKEACKGFLTKQP 588
Query: 297 TRRLGNLQSGPDDIKSHPWFAEVIWEKLVAKDIETPYEPPIAVGVGDSSLFDQYPEEQLD 356
+RLG SG +D++ HP+F + WEK+ ++++ P++P I S+ Q+ E+ D
Sbjct: 589 NKRLGCGSSGEEDVRLHPFFRRIDWEKIENREVQPPFKPKIKHRKDVSNFDKQFTSEKTD 648
>CE18169 [T] KOG0603 Ribosomal protein S6 kinase
Length = 797
Score = 240 bits (612), Expect = 3e-63
Identities = 125/293 (42%), Positives = 188/293 (63%), Gaps = 8/293 (2%)
Query: 62 FQIMRTLGTGSFGRVHLVRSVH---NGRYYAIKVLKKHQIIRMKQIEHTNDERRMLKLVE 118
F++++ LG GSFG+V LVR V +G YA+KVLKK ++++ + T ER +L +
Sbjct: 104 FELLKVLGQGSFGKVFLVRKVRGRDSGHVYAMKVLKK-ATLKVRDRQRTKLERNILAHIS 162
Query: 119 HPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLALEYLHS 178
HPF++++ FQ L++++D++ GG+LF+ L K F KFY AE+TLALE+LHS
Sbjct: 163 HPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEDDVKFYLAELTLALEHLHS 222
Query: 179 HNIIYRDLKPENILLDRNGHIKITDFGFAKEVI---TVTWTLCGTPDYIAPEVITTKPYN 235
I+YRDLKPENILLD +GHIK+TDFG +KE I T++ CGT +Y+APEVI + ++
Sbjct: 223 LGIVYRDLKPENILLDADGHIKVTDFGLSKEAIDSEKKTYSFCGTVEYMAPEVINRRGHS 282
Query: 236 KSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFFHPDVVDLLGKLITAD 295
+ D+WSLG+L+FEML G+ PF T +IL ++ P F + LL L +
Sbjct: 283 MAADFWSLGVLMFEMLTGHLPFQGRDRNDTMTQILKAKLSMPHFLTQEAQSLLRALFKRN 342
Query: 296 LTRRLGNLQSGPDDIKSHPWFAEVIWEKLVAKDIETPYEPPIAVGVGDSSLFD 348
RLG G ++IK H +FA++ + KL+ K+I+ P++P ++ V +S FD
Sbjct: 343 SQNRLGAGPDGVEEIKRHAFFAKIDFVKLLNKEIDPPFKPALST-VDSTSYFD 394
Score = 118 bits (295), Expect = 2e-26
Identities = 81/274 (29%), Positives = 139/274 (50%), Gaps = 28/274 (10%)
Query: 61 DFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRMLKLVEHP 120
D++I+ +G G+ VH + R YA+K++KK + T + +L+ H
Sbjct: 453 DYEILEKIGNGAHSVVHKCQMKATRRKYAVKIVKK------AVFDATEEVDILLRHSHHQ 506
Query: 121 FLIRMWGTFQDSRNLFMVMDYIEGGELFSLL--RKSQRFPNPVAKFYAAEVTLALEYLHS 178
F+++++ ++D ++M+ + EGGEL L +KS VA A + A++YLHS
Sbjct: 507 FVVKLFDVYEDETAIYMIEELCEGGELLDKLVNKKSLGSEKEVAAIMA-NLLNAVQYLHS 565
Query: 179 HNIIYRDLKPENILLDRN----GHIKITDFGFAKEVIT---VTWTLCGTPDYIAPEVITT 231
+ +RDL NIL ++I DFGFAK+ + T C T ++APEV+
Sbjct: 566 QQVAHRDLTAANILFALKDGDPSSLRIVDFGFAKQSRAENGMLMTPCYTAQFVAPEVLRK 625
Query: 232 KPYNKSVDWWSLGILIFEMLAGYTPFY---DVTPMKTYEKILAGEV--VYPPF--FHPDV 284
+ Y++S D WSLG+L+ ML G TPF + TP + +++ G++ +P + +
Sbjct: 626 QGYDRSCDVWSLGVLLHTMLTGCTPFAMGPNDTPDQILQRVGDGKISMTHPVWDTISDEA 685
Query: 285 VDLLGKLITADLTRRLGNLQSGPDDIKSHPWFAE 318
DL+ K++ D RR+ Q+ H W +
Sbjct: 686 KDLVRKMLDVDPNRRVTAKQA-----LQHKWIGQ 714
>CE13014 [T] KOG0603 Ribosomal protein S6 kinase
Length = 740
Score = 240 bits (612), Expect = 3e-63
Identities = 125/293 (42%), Positives = 188/293 (63%), Gaps = 8/293 (2%)
Query: 62 FQIMRTLGTGSFGRVHLVRSVH---NGRYYAIKVLKKHQIIRMKQIEHTNDERRMLKLVE 118
F++++ LG GSFG+V LVR V +G YA+KVLKK ++++ + T ER +L +
Sbjct: 47 FELLKVLGQGSFGKVFLVRKVRGRDSGHVYAMKVLKK-ATLKVRDRQRTKLERNILAHIS 105
Query: 119 HPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLALEYLHS 178
HPF++++ FQ L++++D++ GG+LF+ L K F KFY AE+TLALE+LHS
Sbjct: 106 HPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEDDVKFYLAELTLALEHLHS 165
Query: 179 HNIIYRDLKPENILLDRNGHIKITDFGFAKEVI---TVTWTLCGTPDYIAPEVITTKPYN 235
I+YRDLKPENILLD +GHIK+TDFG +KE I T++ CGT +Y+APEVI + ++
Sbjct: 166 LGIVYRDLKPENILLDADGHIKVTDFGLSKEAIDSEKKTYSFCGTVEYMAPEVINRRGHS 225
Query: 236 KSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFFHPDVVDLLGKLITAD 295
+ D+WSLG+L+FEML G+ PF T +IL ++ P F + LL L +
Sbjct: 226 MAADFWSLGVLMFEMLTGHLPFQGRDRNDTMTQILKAKLSMPHFLTQEAQSLLRALFKRN 285
Query: 296 LTRRLGNLQSGPDDIKSHPWFAEVIWEKLVAKDIETPYEPPIAVGVGDSSLFD 348
RLG G ++IK H +FA++ + KL+ K+I+ P++P ++ V +S FD
Sbjct: 286 SQNRLGAGPDGVEEIKRHAFFAKIDFVKLLNKEIDPPFKPALST-VDSTSYFD 337
Score = 118 bits (295), Expect = 2e-26
Identities = 81/274 (29%), Positives = 139/274 (50%), Gaps = 28/274 (10%)
Query: 61 DFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRMLKLVEHP 120
D++I+ +G G+ VH + R YA+K++KK + T + +L+ H
Sbjct: 396 DYEILEKIGNGAHSVVHKCQMKATRRKYAVKIVKK------AVFDATEEVDILLRHSHHQ 449
Query: 121 FLIRMWGTFQDSRNLFMVMDYIEGGELFSLL--RKSQRFPNPVAKFYAAEVTLALEYLHS 178
F+++++ ++D ++M+ + EGGEL L +KS VA A + A++YLHS
Sbjct: 450 FVVKLFDVYEDETAIYMIEELCEGGELLDKLVNKKSLGSEKEVAAIMA-NLLNAVQYLHS 508
Query: 179 HNIIYRDLKPENILLDRN----GHIKITDFGFAKEVIT---VTWTLCGTPDYIAPEVITT 231
+ +RDL NIL ++I DFGFAK+ + T C T ++APEV+
Sbjct: 509 QQVAHRDLTAANILFALKDGDPSSLRIVDFGFAKQSRAENGMLMTPCYTAQFVAPEVLRK 568
Query: 232 KPYNKSVDWWSLGILIFEMLAGYTPFY---DVTPMKTYEKILAGEV--VYPPF--FHPDV 284
+ Y++S D WSLG+L+ ML G TPF + TP + +++ G++ +P + +
Sbjct: 569 QGYDRSCDVWSLGVLLHTMLTGCTPFAMGPNDTPDQILQRVGDGKISMTHPVWDTISDEA 628
Query: 285 VDLLGKLITADLTRRLGNLQSGPDDIKSHPWFAE 318
DL+ K++ D RR+ Q+ H W +
Sbjct: 629 KDLVRKMLDVDPNRRVTAKQA-----LQHKWIGQ 657
>CE05274 [T] KOG0690 Serine/threonine protein kinase
Length = 546
Score = 239 bits (610), Expect = 5e-63
Identities = 128/316 (40%), Positives = 188/316 (58%), Gaps = 15/316 (4%)
Query: 44 SLLPQRSTVSKGKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQ 103
S+ + K T+ DF ++ LG G+FG+V L + + YAIK+LKK II ++
Sbjct: 175 SIADTSEAAKRDKITMEDFDFLKVLGKGTFGKVILCKEKRTQKLYAIKILKKDVIIAREE 234
Query: 104 IEHTNDERRMLKLVEHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKS-----QRFP 158
+ HT E R+L+ +HPFL + +FQ + L VM++ GG+L+ L + + F
Sbjct: 235 VAHTLTENRVLQRCKHPFLTELKYSFQTNDRLCFVMEFAIGGDLYYHLNREVQMNKEGFS 294
Query: 159 NPVAKFYAAEVTLALEYLHSHNIIYRDLKPENILLDRNGHIKITDFGFAKEVITV---TW 215
P A+FY +E+ LAL YLH+++I+YRDLK EN+LLD++GHIKI DFG KE I+ T
Sbjct: 295 EPRARFYGSEIVLALGYLHANSIVYRDLKLENLLLDKDGHIKIADFGLCKEEISFGDKTS 354
Query: 216 TLCGTPDYIAPEVITTKPYNKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVV 275
T CGTP+Y+APEV+ Y + VDWW +G++++EM+ G PFY K +E I+AG++
Sbjct: 355 TFCGTPEYLAPEVLDDHDYGRCVDWWGVGVVMYEMMCGRLPFYSKDHNKLFELIMAGDLR 414
Query: 276 YPPFFHPDVVDLLGKLITADLTRRLGNLQSGPDD---IKSHPWFAEVIWEKLVAKDIETP 332
+P + LL L+ D T+RLG GP+D I +F V WE K+IE P
Sbjct: 415 FPSKLSQEARTLLTGLLVKDPTQRLG---GGPEDALEICRADFFRTVDWEATYRKEIEPP 471
Query: 333 YEPPIAVGVGDSSLFD 348
Y+P + D+S FD
Sbjct: 472 YKPNVQ-SETDTSYFD 486
>SPAC22E12.14c [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 646
Score = 239 bits (609), Expect = 6e-63
Identities = 135/321 (42%), Positives = 195/321 (60%), Gaps = 11/321 (3%)
Query: 52 VSKGKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDER 111
+S+ Y DF ++ +G G+FG+V+LVR R YA+KVL K I+R K++ HT ER
Sbjct: 256 LSQHSYGPDDFVPLKLIGKGTFGQVYLVRKKDTERVYAMKVLSKKVIVRRKEVAHTVGER 315
Query: 112 RML---KLVEHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAE 168
+L + PF++ + +FQ ++L++V DY+ GGELF L+KS RFP AKFY AE
Sbjct: 316 DILVQTSAADSPFIVALRFSFQTPKDLYLVTDYMAGGELFWHLQKSVRFPEERAKFYIAE 375
Query: 169 VTLALEYLHSHNIIYRDLKPENILLDRNGHIKITDFGFAK---EVITVTWTLCGTPDYIA 225
+ LAL+ LH I+YRDLKPENILLD GHI + DFG +K V T T T CGT DY+A
Sbjct: 376 LLLALQALHKRGIVYRDLKPENILLDVQGHIALCDFGLSKANLSVGTTTRTFCGTTDYLA 435
Query: 226 PEVITTKP-YNKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYP-PFFHPD 283
PEVI + Y+ VD+WSLG+L++EM G++PFY + Y+ I+ G+V +P +
Sbjct: 436 PEVILDEAGYDMMVDFWSLGVLLYEMTCGWSPFYADNTQQLYKNIVFGKVRFPRGLLSVE 495
Query: 284 VVDLLGKLITADLTRRLGNLQSGPDDIKSHPWFAEVIWEKLVAKDIETPYEPPIAVGVGD 343
DL+ L+ + RLG +++ HP+F + W+KL AK+I P++ PI G D
Sbjct: 496 ARDLIKLLLNRNPKHRLG-AHGDVEEVMKHPFFDGIDWKKLAAKEISPPFK-PIVEGEID 553
Query: 344 SSLFD-QYPEEQLDYGVQGED 363
S FD ++ + +D D
Sbjct: 554 VSNFDVEFTNKAIDRDFSSTD 574
>7296166 [T] KOG0614 cGMP-dependent protein kinase
Length = 768
Score = 239 bits (609), Expect = 6e-63
Identities = 131/331 (39%), Positives = 194/331 (58%), Gaps = 10/331 (3%)
Query: 30 GSQSTDYLLAQQKESLLPQRSTVSKGKYT---LHDFQIMRTLGTGSFGRVHLVRSVHNGR 86
G +S + Q +ES + + ++ L D +++ TLG G FGRV LV++ H R
Sbjct: 422 GDESRKLAMKQAQESCRDEPKEQLQQEFPDLKLTDLEVVSTLGIGGFGRVELVKAHHQDR 481
Query: 87 Y--YAIKVLKKHQIIRMKQIEHTNDERRMLKLVEHPFLIRMWGTFQDSRNLFMVMDYIEG 144
+A+K LKK I+ KQ EH ER ++ PF+ R++ TF+D + ++M+++ G
Sbjct: 482 VDIFALKCLKKRHIVDTKQEEHIFSERHIMLSSRSPFICRLYRTFRDEKYVYMLLEACMG 541
Query: 145 GELFSLLRKSQRFPNPVAKFYAAEVTLALEYLHSHNIIYRDLKPENILLDRNGHIKITDF 204
GE++++LR F + A+F V A EYLH+ IIYRDLKPEN++LD G++KI DF
Sbjct: 542 GEIWTMLRDRGSFEDNAAQFIIGCVLQAFEYLHARGIIYRDLKPENLMLDERGYVKIVDF 601
Query: 205 GFAKEVIT--VTWTLCGTPDYIAPEVITTKPYNKSVDWWSLGILIFEMLAGYTPFYDVTP 262
GFAK++ T TWT CGTP+Y+APE+I K ++++VD+W+LGILI E+L G PF P
Sbjct: 602 GFAKQIGTSSKTWTFCGTPEYVAPEIILNKGHDRAVDYWALGILIHELLNGTPPFSAPDP 661
Query: 263 MKTYEKILAG--EVVYPPFFHPDVVDLLGKLITADLTRRLGNLQSGPDDIKSHPWFAEVI 320
M+TY IL G + +P V L+ +L + RLG G DIK H WF
Sbjct: 662 MQTYNLILKGIDMIAFPKHISRWAVQLIKRLCRDVPSERLGYQTGGIQDIKKHKWFLGFD 721
Query: 321 WEKLVAKDIETPYEPPIAVGVGDSSLFDQYP 351
W+ L ++ + P+ PIA D FD++P
Sbjct: 722 WDGLASQLLIPPFVRPIAHPT-DVRYFDRFP 751
>CE29298 [T] KOG0690 Serine/threonine protein kinase
Length = 483
Score = 238 bits (608), Expect = 8e-63
Identities = 124/310 (40%), Positives = 190/310 (61%), Gaps = 15/310 (4%)
Query: 46 LPQRSTVSKGKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIE 105
+P+++TV T+ DF ++ LG G+FG+V L R + + YAIK+++K ++ ++
Sbjct: 169 VPRKNTV-----TMDDFDFLKVLGQGTFGKVILCREKSSDKLYAIKIIRKEMVVDRSEVA 223
Query: 106 HTNDERRMLKLVEHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFY 165
HT E R+L HPFL + +FQ ++ VM++ GGELF+ L++ + F +FY
Sbjct: 224 HTLTENRVLYACVHPFLTLLKYSFQAQYHICFVMEFANGGELFTHLQRCKTFSEARTRFY 283
Query: 166 AAEVTLALEYLHSHNIIYRDLKPENILLDRNGHIKITDFGFAKEVITV---TWTLCGTPD 222
+E+ LAL YLH NI+YRD+K EN+LLDR+GHIKITDFG KE I T T CGTP+
Sbjct: 284 GSEIILALGYLHHRNIVYRDMKLENLLLDRDGHIKITDFGLCKEEIKYGDKTSTFCGTPE 343
Query: 223 YIAPEVITTKPYNKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFFHP 282
Y+APEVI Y++SVDWW +G++++EM+ G PF K +E I ++ +P P
Sbjct: 344 YLAPEVIEDIDYDRSVDWWGVGVVMYEMMCGRLPFSAKENGKLFELITTCDLKFPNRLSP 403
Query: 283 DVVDLLGKLITADLTRRLGNLQSGPDD---IKSHPWFAEVIWEKLVAKDIETPYEPPIAV 339
+ V LL L+ +RLG +GPDD + +F +V WE + K++E P++P + +
Sbjct: 404 EAVTLLSGLLERVPAKRLG---AGPDDAREVSRAEFFKDVDWEATLRKEVEPPFKPNV-M 459
Query: 340 GVGDSSLFDQ 349
D+S FD+
Sbjct: 460 SETDTSFFDR 469
>CE18646 [T] KOG0690 Serine/threonine protein kinase
Length = 528
Score = 238 bits (608), Expect = 8e-63
Identities = 124/310 (40%), Positives = 190/310 (61%), Gaps = 15/310 (4%)
Query: 46 LPQRSTVSKGKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIE 105
+P+++TV T+ DF ++ LG G+FG+V L R + + YAIK+++K ++ ++
Sbjct: 169 VPRKNTV-----TMDDFDFLKVLGQGTFGKVILCREKSSDKLYAIKIIRKEMVVDRSEVA 223
Query: 106 HTNDERRMLKLVEHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFY 165
HT E R+L HPFL + +FQ ++ VM++ GGELF+ L++ + F +FY
Sbjct: 224 HTLTENRVLYACVHPFLTLLKYSFQAQYHICFVMEFANGGELFTHLQRCKTFSEARTRFY 283
Query: 166 AAEVTLALEYLHSHNIIYRDLKPENILLDRNGHIKITDFGFAKEVITV---TWTLCGTPD 222
+E+ LAL YLH NI+YRD+K EN+LLDR+GHIKITDFG KE I T T CGTP+
Sbjct: 284 GSEIILALGYLHHRNIVYRDMKLENLLLDRDGHIKITDFGLCKEEIKYGDKTSTFCGTPE 343
Query: 223 YIAPEVITTKPYNKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFFHP 282
Y+APEVI Y++SVDWW +G++++EM+ G PF K +E I ++ +P P
Sbjct: 344 YLAPEVIEDIDYDRSVDWWGVGVVMYEMMCGRLPFSAKENGKLFELITTCDLKFPNRLSP 403
Query: 283 DVVDLLGKLITADLTRRLGNLQSGPDD---IKSHPWFAEVIWEKLVAKDIETPYEPPIAV 339
+ V LL L+ +RLG +GPDD + +F +V WE + K++E P++P + +
Sbjct: 404 EAVTLLSGLLERVPAKRLG---AGPDDAREVSRAEFFKDVDWEATLRKEVEPPFKPNV-M 459
Query: 340 GVGDSSLFDQ 349
D+S FD+
Sbjct: 460 SETDTSFFDR 469
>CE02586 [T] KOG0696 Serine/threonine protein kinase
Length = 861
Score = 238 bits (606), Expect = 1e-62
Identities = 130/311 (41%), Positives = 184/311 (58%), Gaps = 12/311 (3%)
Query: 39 AQQKESLLPQRSTVSKGKYTLH-----DFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVL 93
++ K+ P+ ST+ G + DF + LG GSFG+V L +AIKVL
Sbjct: 385 SKPKDPAAPRASTLPLGSSNHNVIKASDFNFLTVLGKGSFGKVLLGEQKTTKELFAIKVL 444
Query: 94 KKHQIIRMKQIEHTNDERRMLKLVEHP-FLIRMWGTFQDSRNLFMVMDYIEGGELFSLLR 152
KK II+ +E T E+R+L L E P FL+ + FQ L+ VM+++ GG+L ++
Sbjct: 445 KKDVIIQDDDVECTMTEKRVLALPEKPSFLVALHSCFQTMDRLYFVMEFVNGGDLMYQIQ 504
Query: 153 KSQRFPNPVAKFYAAEVTLALEYLHSHNIIYRDLKPENILLDRNGHIKITDFGFAKEVI- 211
+ +F PVA FYAAE+ + L +LHS IIYRDLK +N++L+R+GHIKITDFG KE I
Sbjct: 505 QVGKFKEPVAVFYAAEIAVGLFFLHSKGIIYRDLKLDNVMLERDGHIKITDFGMCKENIF 564
Query: 212 --TVTWTLCGTPDYIAPEVITTKPYNKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKI 269
T T CGTPDYIAPE+I +PY KSVDWW+ G+L+FEMLAG PF + + I
Sbjct: 565 GDATTKTFCGTPDYIAPEIILYQPYGKSVDWWAYGVLLFEMLAGQPPFDGEDEDELFTAI 624
Query: 270 LAGEVVYPPFFHPDVVDLLGKLITADLTRRL---GNLQSGPDDIKSHPWFAEVIWEKLVA 326
V YP + V L L+ + ++RL G+ +S DIK HP+F + W K+
Sbjct: 625 TEHNVSYPKSLSKEAVSLCKALLIKNPSKRLGCTGDDESASRDIKEHPFFRRIDWFKIET 684
Query: 327 KDIETPYEPPI 337
+ I+ P++P +
Sbjct: 685 RQIQPPFKPKL 695
>Hs22068916 [T] KOG0696 Serine/threonine protein kinase
Length = 673
Score = 237 bits (604), Expect = 2e-62
Identities = 124/287 (43%), Positives = 171/287 (59%), Gaps = 4/287 (1%)
Query: 53 SKGKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERR 112
++ + L DF + LG GSFG+V L YA+K+LKK +I+ +E T E+R
Sbjct: 333 NRDRMKLTDFNFLMVLGKGSFGKVMLSERKGTDELYAVKILKKDVVIQDDDVECTMVEKR 392
Query: 113 MLKLV-EHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTL 171
+L L + PFL ++ FQ L+ VM+Y+ GG+L +++ RF P A FYAAE+ +
Sbjct: 393 VLALPGKPPFLTQLHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGRFKEPHAVFYAAEIAI 452
Query: 172 ALEYLHSHNIIYRDLKPENILLDRNGHIKITDFGFAKEVI---TVTWTLCGTPDYIAPEV 228
L +L S IIYRDLK +N++LD GHIKI DFG KE I T T CGTPDYIAPE+
Sbjct: 453 GLFFLQSKGIIYRDLKLDNVMLDSEGHIKIADFGMCKENIWDGVTTKTFCGTPDYIAPEI 512
Query: 229 ITTKPYNKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFFHPDVVDLL 288
I +PY KSVDWW+ G+L++EMLAG PF + ++ I+ V YP + V +
Sbjct: 513 IAYQPYGKSVDWWAFGVLLYEMLAGQAPFEGEDEDELFQSIMEHNVAYPKSMSKEAVAIC 572
Query: 289 GKLITADLTRRLGNLQSGPDDIKSHPWFAEVIWEKLVAKDIETPYEP 335
L+T +RLG G DIK H +F + WEKL K+I+ PY+P
Sbjct: 573 KGLMTKHPGKRLGCGPEGERDIKEHAFFRYIDWEKLERKEIQPPYKP 619
>Hs20127450 [T] KOG0696 Serine/threonine protein kinase
Length = 673
Score = 237 bits (604), Expect = 2e-62
Identities = 124/287 (43%), Positives = 171/287 (59%), Gaps = 4/287 (1%)
Query: 53 SKGKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERR 112
++ + L DF + LG GSFG+V L YA+K+LKK +I+ +E T E+R
Sbjct: 333 NRDRMKLTDFNFLMVLGKGSFGKVMLSERKGTDELYAVKILKKDVVIQDDDVECTMVEKR 392
Query: 113 MLKLV-EHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTL 171
+L L + PFL ++ FQ L+ VM+Y+ GG+L +++ RF P A FYAAE+ +
Sbjct: 393 VLALPGKPPFLTQLHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGRFKEPHAVFYAAEIAI 452
Query: 172 ALEYLHSHNIIYRDLKPENILLDRNGHIKITDFGFAKEVI---TVTWTLCGTPDYIAPEV 228
L +L S IIYRDLK +N++LD GHIKI DFG KE I T T CGTPDYIAPE+
Sbjct: 453 GLFFLQSKGIIYRDLKLDNVMLDSEGHIKIADFGMCKENIWDGVTTKTFCGTPDYIAPEI 512
Query: 229 ITTKPYNKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFFHPDVVDLL 288
I +PY KSVDWW+ G+L++EMLAG PF + ++ I+ V YP + V +
Sbjct: 513 IAYQPYGKSVDWWAFGVLLYEMLAGQAPFEGEDEDELFQSIMEHNVAYPKSMSKEAVAIC 572
Query: 289 GKLITADLTRRLGNLQSGPDDIKSHPWFAEVIWEKLVAKDIETPYEP 335
L+T +RLG G DIK H +F + WEKL K+I+ PY+P
Sbjct: 573 KGLMTKHPGKRLGCGPEGERDIKEHAFFRYIDWEKLERKEIQPPYKP 619
>SPAC1B9.02c [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 696
Score = 236 bits (602), Expect = 4e-62
Identities = 129/305 (42%), Positives = 187/305 (61%), Gaps = 16/305 (5%)
Query: 56 KYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRML- 114
+Y DF +R +G G+FG+V+LVR R YA+K + K I+R K++ HT ER +L
Sbjct: 296 RYGPEDFTALRLIGKGTFGQVYLVRKNDTNRIYAMKKISKKLIVRKKEVTHTLGERNILV 355
Query: 115 --KLVEHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLA 172
L E PF++ + +FQ + +L+++ DY+ GGELF L+ RFP AKFY AE+ LA
Sbjct: 356 RTSLDESPFIVGLKFSFQTASDLYLITDYMSGGELFWHLQHEGRFPEQRAKFYIAELVLA 415
Query: 173 LEYLHSHNIIYRDLKPENILLDRNGHIKITDFGFAKEVIT---VTWTLCGTPDYIAPEV- 228
LE+LH H+IIYRDLKPENILLD +GHI + DFG +K ++ T T CGT +Y+APEV
Sbjct: 416 LEHLHKHDIIYRDLKPENILLDADGHIALCDFGLSKANLSANATTNTFCGTTEYLAPEVL 475
Query: 229 ITTKPYNKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFFHPDVVDLL 288
+ K Y K VD+WSLG+L+FEM G++PFY + Y I G+V +P V+
Sbjct: 476 LEDKGYTKQVDFWSLGVLVFEMCCGWSPFYAPDVQQMYRNIAFGKVRFP----KGVLSSE 531
Query: 289 GKLITADLTRRLGNLQSG----PDDIKSHPWFAEVIWEKLVAKDIETPYEPPIAVGVGDS 344
G+ L R N + G ++K HP+FA++ W+ L K ++ P++P + + D
Sbjct: 532 GRSFVRGLLNRNPNHRLGAVADTTELKEHPFFADINWDLLSKKKVQPPFKPNVQNDL-DV 590
Query: 345 SLFDQ 349
S FD+
Sbjct: 591 SNFDK 595
>7295426 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 490
Score = 236 bits (602), Expect = 4e-62
Identities = 131/319 (41%), Positives = 189/319 (59%), Gaps = 16/319 (5%)
Query: 42 KESLLPQRSTVSKGKYTL--HDFQIMRTLGTGSFGRVHLVRSVHN---GRYYAIKVLKKH 96
+E++ V+ GK L DF++ + LG G +G+V VR +Y+A+KVLKK
Sbjct: 55 QETIQLCEENVNPGKIKLGPKDFELKKVLGKGGYGKVFQVRKTAGRDANKYFAMKVLKKA 114
Query: 97 QII-RMKQIEHTNDERRMLKLVEHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQ 155
I+ K HT ER +L+ V+HPF++ + FQ L+++++Y+ GGELF L +
Sbjct: 115 SIVTNQKDTAHTRAERNILEAVKHPFIVELVYAFQTDGKLYLILEYLSGGELFMHLEREG 174
Query: 156 RFPNPVAKFYAAEVTLALEYLHSHNIIYRDLKPENILLDRNGHIKITDFGFAKEVI---T 212
F FY +E+ LAL +LH IIYRDLKPENILLD GH+K+TDFG KE I
Sbjct: 175 IFLEDTTCFYLSEIILALGHLHKLGIIYRDLKPENILLDAQGHVKLTDFGLCKEHIQEGI 234
Query: 213 VTWTLCGTPDYIAPEVITTKPYNKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAG 272
VT T CGT +Y+APE++T + K+VDWWSLG L+F+ML G PF KT E IL
Sbjct: 235 VTHTFCGTIEYMAPEILTRSGHGKAVDWWSLGALMFDMLTGVPPFTAENRKKTIETILKA 294
Query: 273 EVVYPPFFHPDVVDLLGKLITADLTRRLGNLQSGPDD---IKSHPWFAEVIWEKLVAKDI 329
++ P + P+ DL+ +L+ +RLG SGP+D ++ HP+F V W+ ++A+ +
Sbjct: 295 KLNLPAYLTPEARDLVRRLMKRQEPQRLG---SGPEDAAAVQIHPFFKHVNWDDVLARRL 351
Query: 330 ETPYEPPIAVGVGDSSLFD 348
E P + P+ D S FD
Sbjct: 352 EPPIK-PLLRSEDDVSQFD 369
>Hs4506067 [T] KOG0696 Serine/threonine protein kinase
Length = 672
Score = 235 bits (599), Expect = 9e-62
Identities = 123/296 (41%), Positives = 178/296 (59%), Gaps = 6/296 (2%)
Query: 59 LHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRMLKLVE 118
L DF + LG GSFG+V L YAIK+LKK +I+ +E T E+R+L L++
Sbjct: 336 LTDFNFLMVLGKGSFGKVMLADRKGTEELYAIKILKKDVVIQDDDVECTMVEKRVLALLD 395
Query: 119 HP-FLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLALEYLH 177
P FL ++ FQ L+ VM+Y+ GG+L +++ +F P A FYAAE+++ L +LH
Sbjct: 396 KPPFLTQLHSCFQTVDRLYFVMEYVNGGDLMYHIQQVGKFKEPQAVFYAAEISIGLFFLH 455
Query: 178 SHNIIYRDLKPENILLDRNGHIKITDFGFAKEVI---TVTWTLCGTPDYIAPEVITTKPY 234
IIYRDLK +N++LD GHIKI DFG KE + T T CGTPDYIAPE+I +PY
Sbjct: 456 KRGIIYRDLKLDNVMLDSEGHIKIADFGMCKEHMMDGVTTRTFCGTPDYIAPEIIAYQPY 515
Query: 235 NKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFFHPDVVDLLGKLITA 294
KSVDWW+ G+L++EMLAG PF + ++ I+ V YP + V + L+T
Sbjct: 516 GKSVDWWAYGVLLYEMLAGQPPFDGEDEDELFQSIMEHNVSYPKSLSKEAVSICKGLMTK 575
Query: 295 DLTRRLGNLQSGPDDIKSHPWFAEVIWEKLVAKDIETPYEPPIAVGVGDSSLFDQY 350
+RLG G D++ H +F + WEKL ++I+ P++P + G G + FD++
Sbjct: 576 HPAKRLGCGPEGERDVREHAFFRRIDWEKLENREIQPPFKPKVC-GKGAEN-FDKF 629
>YHR205w [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 824
Score = 234 bits (596), Expect = 2e-61
Identities = 131/305 (42%), Positives = 191/305 (61%), Gaps = 16/305 (5%)
Query: 54 KGKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRM 113
K Y DF+++R LG G+FG+V+ V+ R YA+KVL K I++ +I HT ER +
Sbjct: 404 KRHYGPQDFEVLRLLGKGTFGQVYQVKKKDTQRIYAMKVLSKKVIVKKNEIAHTIGERNI 463
Query: 114 LKLV---EHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVT 170
L PF++ + +FQ +L++V DY+ GGELF L+K RF AKFY AE+
Sbjct: 464 LVTTASKSSPFIVGLKFSFQTPTDLYLVTDYMSGGELFWHLQKEGRFSEDRAKFYIAELV 523
Query: 171 LALEYLHSHNIIYRDLKPENILLDRNGHIKITDFGFAK-EVITVTWTLCGTPDYIAPEVI 229
LALE+LH ++I+YRDLKPENILLD NG+I + DFG +K ++ T T CGT +Y+APE++
Sbjct: 524 LALEHLHDNDIVYRDLKPENILLDANGNIALCDFGLSKADLKDRTNTFCGTTEYLAPELL 583
Query: 230 TTKP-YNKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFFHPDVVDLL 288
+ Y K VD+WSLG+LIFEM G++PF+ K Y+KI G+V +P DV+
Sbjct: 584 LDETGYTKMVDFWSLGVLIFEMCCGWSPFFAENNQKMYQKIAFGKVKFP----RDVLSQE 639
Query: 289 GK-----LITADLTRRLGNLQSGPDDIKSHPWFAEVIWEKLVAKDIETPYEPPIAVGVGD 343
G+ L+ + RLG + G ++++HP+FA++ WE L K I P++P + V D
Sbjct: 640 GRSFVKGLLNRNPKHRLGAIDDG-RELRAHPFFADIDWEALKQKKIPPPFKPHL-VSETD 697
Query: 344 SSLFD 348
+S FD
Sbjct: 698 TSNFD 702
>Hs4506735 [T] KOG0603 Ribosomal protein S6 kinase
Length = 772
Score = 233 bits (594), Expect = 3e-61
Identities = 128/325 (39%), Positives = 192/325 (58%), Gaps = 14/325 (4%)
Query: 56 KYTLHDFQIMRTLGTGSFGRVHLVRSVHN---GRYYAIKVLKKHQII-RMKQIEHTNDER 111
K ++ +F++++ LGTG++G+V LVR G+ YA+KVL+K ++ R K EHT ER
Sbjct: 27 KVSVENFELLKVLGTGAYGKVFLVRKAGGHDAGKLYAMKVLRKAALVQRAKTQEHTRTER 86
Query: 112 RMLKLVEH-PFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVT 170
+L+LV PFL+ + FQ L +++DY+ GGE+F+ L + Q F + Y E+
Sbjct: 87 SVLELVRQAPFLVTLHYAFQTDAKLHLILDYVSGGEMFTHLYQRQYFKEAEVRVYGGEIV 146
Query: 171 LALEYLHSHNIIYRDLKPENILLDRNGHIKITDFGFAKEVITV----TWTLCGTPDYIAP 226
LALE+LH IIYRDLK EN+LLD GHI +TDFG +KE +T T++ CGT +Y+AP
Sbjct: 147 LALEHLHKLGIIYRDLKLENVLLDSEGHIVLTDFGLSKEFLTEEKERTFSFCGTIEYMAP 206
Query: 227 EVITTKP-YNKSVDWWSLGILIFEMLAGYTPF----YDVTPMKTYEKILAGEVVYPPFFH 281
E+I +K + K+VDWWSLGIL+FE+L G +PF T + +IL +PP
Sbjct: 207 EIIRSKTGHGKAVDWWSLGILLFELLTGASPFTLEGERNTQAEVSRRILKCSPPFPPRIG 266
Query: 282 PDVVDLLGKLITADLTRRLGNLQSGPDDIKSHPWFAEVIWEKLVAKDIETPYEPPIAVGV 341
P DLL +L+ D +RLG G ++++HP+F + W L A+ I P+ P I +
Sbjct: 267 PVAQDLLQRLLCKDPKKRLGAGPQGAQEVRNHPFFQGLDWVALAARKIPAPFRPQIRSEL 326
Query: 342 GDSSLFDQYPEEQLDYGVQGEDPYG 366
+ +++ + Y G P G
Sbjct: 327 DVGNFAEEFTRLEPVYSPPGSPPPG 351
Score = 104 bits (259), Expect = 2e-22
Identities = 65/199 (32%), Positives = 105/199 (52%), Gaps = 15/199 (7%)
Query: 68 LGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRMLKLVE-HPFLIRMW 126
LG GSF R +G+ +A+K+L + + +T E L+L + HP ++ +
Sbjct: 417 LGQGSFSVCRRCRQRQSGQEFAVKILSR------RLEANTQREVAALRLCQSHPNVVNLH 470
Query: 127 GTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLALEYLHSH-NIIYRD 185
D + ++V++ + GGEL +RK + F A + A+ ++H +++RD
Sbjct: 471 EVHHDQLHTYLVLELLRGGELLEHIRKKRHFSESEASQILRSLVSAVSFMHEEAGVVHRD 530
Query: 186 LKPENILL--DRNGH-IKITDFGFAK----EVITVTWTLCGTPDYIAPEVITTKPYNKSV 238
LKPENIL D G +KI DFGFA+ T C T Y APE++ + Y++S
Sbjct: 531 LKPENILYADDTPGAPVKIIDFGFARLRPQSPGVPMQTPCFTLQYAAPELLAQQGYDESC 590
Query: 239 DWWSLGILIFEMLAGYTPF 257
D WSLG++++ ML+G PF
Sbjct: 591 DLWSLGVILYMMLSGQVPF 609
>SPBC12D12.04c [T] KOG0694 Serine/threonine protein kinase
Length = 1016
Score = 232 bits (592), Expect = 6e-61
Identities = 119/312 (38%), Positives = 186/312 (59%), Gaps = 8/312 (2%)
Query: 44 SLLPQRSTVSKGKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQ 103
S++ Q T + L DF + LG G+FG+V L + YAIKVLKK I+ +
Sbjct: 665 SVVAQDLTHKAKRIGLEDFTFLSVLGKGNFGKVMLAELKSEKQLYAIKVLKKEFILENDE 724
Query: 104 IEHTNDERRMLKLVE---HPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNP 160
+E T E+R+ + HPFL+ + FQ ++ VMD++ GG+L +++ Q F
Sbjct: 725 VESTKSEKRVFLVANRERHPFLVNLHSCFQTETRIYFVMDFVSGGDLMLHIQQEQ-FSRR 783
Query: 161 VAKFYAAEVTLALEYLHSHNIIYRDLKPENILLDRNGHIKITDFGFAKEVI---TVTWTL 217
A+FYAAEV LAL+Y H + IIYRDLK +NILL +GH+K+ D+G KE + T T
Sbjct: 784 RAQFYAAEVCLALKYFHDNGIIYRDLKLDNILLSPDGHVKVADYGLCKEDMWHDNTTATF 843
Query: 218 CGTPDYIAPEVITTKPYNKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYP 277
CGTP+++APE++ + Y +SVDWW+ G+LI++ML G +PF + ++ IL+ E +YP
Sbjct: 844 CGTPEFMAPEILLEQQYTRSVDWWAFGVLIYQMLLGQSPFRGEDEEEIFDAILSDEPLYP 903
Query: 278 PFFHPDVVDLLGKLITADLTRRLGNLQSGPDDIKSHPWFAEVIWEKLVAKDIETPYEPPI 337
D V +L +L+T D +RLG+ + +D+ +HP+F+ + W+ + K + PY P +
Sbjct: 904 IHMPRDSVSILQQLLTRDPKKRLGSGPNDAEDVMTHPFFSNINWDDIYHKRTQPPYIPSL 963
Query: 338 AVGVGDSSLFDQ 349
D+ FD+
Sbjct: 964 N-SPTDTKYFDE 974
>Hs20149547 [T] KOG0603 Ribosomal protein S6 kinase
Length = 735
Score = 232 bits (591), Expect = 8e-61
Identities = 118/283 (41%), Positives = 175/283 (61%), Gaps = 7/283 (2%)
Query: 62 FQIMRTLGTGSFGRVHLVRSV---HNGRYYAIKVLKKHQIIRMKQIEHTNDERRMLKLVE 118
F++++ LG GSFG+V LVR V +G YA+KVLKK ++++ T ER +L V
Sbjct: 62 FELLKVLGQGSFGKVFLVRKVTRPDSGHLYAMKVLKK-ATLKVRDRVRTKMERDILADVN 120
Query: 119 HPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLALEYLHS 178
HPF++++ FQ L++++D++ GG+LF+ L K F KFY AE+ L L++LHS
Sbjct: 121 HPFVVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALGLDHLHS 180
Query: 179 HNIIYRDLKPENILLDRNGHIKITDFGFAKEVI---TVTWTLCGTPDYIAPEVITTKPYN 235
IIYRDLKPENILLD GHIK+TDFG +KE I ++ CGT +Y+APEV+ + ++
Sbjct: 181 LGIIYRDLKPENILLDEEGHIKLTDFGLSKEAIDHEKKAYSFCGTVEYMAPEVVNRQGHS 240
Query: 236 KSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFFHPDVVDLLGKLITAD 295
S DWWS G+L+FEML G PF +T IL ++ P F + LL L +
Sbjct: 241 HSADWWSYGVLMFEMLTGSLPFQGKDRKETMTLILKAKLGMPQFLSTEAQSLLRALFKRN 300
Query: 296 LTRRLGNLQSGPDDIKSHPWFAEVIWEKLVAKDIETPYEPPIA 338
RLG+ G ++IK H +++ + W KL ++I+ P++P +A
Sbjct: 301 PANRLGSGPDGAEEIKRHVFYSTIDWNKLYRREIKPPFKPAVA 343
Score = 130 bits (328), Expect = 2e-30
Identities = 86/273 (31%), Positives = 144/273 (52%), Gaps = 29/273 (10%)
Query: 62 FQIMRTLGTGSFGRVHLVRSVHNGRY--YAIKVLKKHQIIRMKQIEHTNDERRMLKLVEH 119
+ + T+G GS+ R VH YA+KV+ K + ++IE +L+ +H
Sbjct: 418 YVVKETIGVGSYSECK--RCVHKATNMEYAVKVIDKSKRDPSEEIEI------LLRYGQH 469
Query: 120 PFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLALEYLHSH 179
P +I + + D +++++V + + GGEL + + + F A F + +EYLHS
Sbjct: 470 PNIITLKDVYDDGKHVYLVTELMRGGELLDKILRQKFFSEREASFVLHTIGKTVEYLHSQ 529
Query: 180 NIIYRDLKPENIL-LDRNGH---IKITDFGFAKEVIT---VTWTLCGTPDYIAPEVITTK 232
+++RDLKP NIL +D +G+ ++I DFGFAK++ + T C T +++APEV+ +
Sbjct: 530 GVVHRDLKPSNILYVDESGNPECLRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQ 589
Query: 233 PYNKSVDWWSLGILIFEMLAGYTPFYD---VTPMKTYEKILAGEVVYP----PFFHPDVV 285
Y++ D WSLGIL++ MLAGYTPF + TP + +I +G+
Sbjct: 590 GYDEGCDIWSLGILLYTMLAGYTPFANGPSDTPEEILTRIGSGKFTLSGGNWNTVSETAK 649
Query: 286 DLLGKLITADLTRRLGNLQSGPDDIKSHPWFAE 318
DL+ K++ D +RL Q + HPW +
Sbjct: 650 DLVSKMLHVDPHQRLTAKQ-----VLQHPWVTQ 677
>SPAC17G8.14c [T] KOG0694 Serine/threonine protein kinase
Length = 896
Score = 231 bits (590), Expect = 1e-60
Identities = 116/290 (40%), Positives = 184/290 (63%), Gaps = 7/290 (2%)
Query: 54 KGKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRM 113
K + TL DF + LG G+FG+V L N ++YAIKVLKK I++ +++E E+ +
Sbjct: 564 KNRVTLDDFTFLAVLGKGNFGKVMLAEYKVNKKFYAIKVLKKEAILKNEELESLKTEKHV 623
Query: 114 LKLV---EHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVT 170
++ +HPFL+ ++ +FQ S ++ VM+YI GG+L +++ Q+F A+FY AEV
Sbjct: 624 FEVANKEKHPFLLNLFASFQTSTRVYFVMEYILGGDLMVHIQR-QQFSVKRARFYGAEVC 682
Query: 171 LALEYLHSHNIIYRDLKPENILLDRNGHIKITDFGFAKEVITV---TWTLCGTPDYIAPE 227
LAL+Y H + I YRDLK +NILL +GHI+I D+G KE + + T T CGTP+++APE
Sbjct: 683 LALKYFHENGIAYRDLKLDNILLCPDGHIRIADYGLCKENMLLGNTTSTFCGTPEFMAPE 742
Query: 228 VITTKPYNKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFFHPDVVDL 287
++ + Y+K VDWW+ G+L+++ML G +PF + ++ IL+ E ++P D V L
Sbjct: 743 ILLEQQYSKDVDWWAFGVLMYQMLLGQSPFKGEDEEEIFDAILSDEPLFPINMPADAVSL 802
Query: 288 LGKLITADLTRRLGNLQSGPDDIKSHPWFAEVIWEKLVAKDIETPYEPPI 337
L L+T D +RLG+ +++ +HP+FA ++W+ L K E Y+P I
Sbjct: 803 LRGLLTRDPNQRLGSGPKDANEVMAHPFFASIVWDDLYNKLYEPSYKPLI 852
>Hs4759050 [T] KOG0603 Ribosomal protein S6 kinase
Length = 740
Score = 231 bits (589), Expect = 1e-60
Identities = 117/280 (41%), Positives = 172/280 (60%), Gaps = 7/280 (2%)
Query: 62 FQIMRTLGTGSFGRVHLVRSVHNG---RYYAIKVLKKHQIIRMKQIEHTNDERRMLKLVE 118
F++++ LG GSFG+V LV+ + + YA+KVLKK ++++ T ER +L V
Sbjct: 68 FELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKK-ATLKVRDRVRTKMERDILVEVN 126
Query: 119 HPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLALEYLHS 178
HPF++++ FQ L++++D++ GG+LF+ L K F KFY AE+ LAL++LHS
Sbjct: 127 HPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLHS 186
Query: 179 HNIIYRDLKPENILLDRNGHIKITDFGFAKEVI---TVTWTLCGTPDYIAPEVITTKPYN 235
IIYRDLKPENILLD GHIK+TDFG +KE I ++ CGT +Y+APEV+ + +
Sbjct: 187 LGIIYRDLKPENILLDEEGHIKLTDFGLSKESIDHEKKAYSFCGTVEYMAPEVVNRRGHT 246
Query: 236 KSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFFHPDVVDLLGKLITAD 295
+S DWWS G+L+FEML G PF +T IL ++ P F P+ LL L +
Sbjct: 247 QSADWWSFGVLMFEMLTGTLPFQGKDRKETMTMILKAKLGMPQFLSPEAQSLLRMLFKRN 306
Query: 296 LTRRLGNLQSGPDDIKSHPWFAEVIWEKLVAKDIETPYEP 335
RLG G ++IK H +F+ + W KL ++I P++P
Sbjct: 307 PANRLGAGPDGVEEIKRHSFFSTIDWNKLYRREIHPPFKP 346
Score = 125 bits (315), Expect = 8e-29
Identities = 84/293 (28%), Positives = 149/293 (50%), Gaps = 27/293 (9%)
Query: 62 FQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRMLKLVEHPF 121
+++ +G GS+ +A+K++ K + ++IE +L+ +HP
Sbjct: 422 YEVKEDIGVGSYSVCKRCIHKATNMEFAVKIIDKSKRDPTEEIEI------LLRYGQHPN 475
Query: 122 LIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLALEYLHSHNI 181
+I + + D + +++V + ++GGEL + + + F A +T +EYLH+ +
Sbjct: 476 IITLKDVYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEYLHAQGV 535
Query: 182 IYRDLKPENIL-LDRNGH---IKITDFGFAKEVIT---VTWTLCGTPDYIAPEVITTKPY 234
++RDLKP NIL +D +G+ I+I DFGFAK++ + T C T +++APEV+ + Y
Sbjct: 536 VHRDLKPSNILYVDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQGY 595
Query: 235 NKSVDWWSLGILIFEMLAGYTPFY---DVTPMKTYEKILAGEVVYPPFFHPDV----VDL 287
+ + D WSLG+L++ ML GYTPF D TP + +I +G+ + V DL
Sbjct: 596 DAACDIWSLGVLLYTMLTGYTPFANGPDDTPEEILARIGSGKFSLSGGYWNSVSDTAKDL 655
Query: 288 LGKLITADLTRRLGNLQSGPDDIKSHPWFAEVIWEKLVAKDIETPYEPPIAVG 340
+ K++ D +RL + HPW V W++L + P + G
Sbjct: 656 VSKMLHVDPHQRLTAAL-----VLRHPWI--VHWDQLPQYQLNRQDAPHLVKG 701
>Hs19923570 [T] KOG0603 Ribosomal protein S6 kinase
Length = 733
Score = 231 bits (589), Expect = 1e-60
Identities = 119/282 (42%), Positives = 173/282 (61%), Gaps = 7/282 (2%)
Query: 62 FQIMRTLGTGSFGRVHLVRSVHN---GRYYAIKVLKKHQIIRMKQIEHTNDERRMLKLVE 118
F++++ LG GS+G+V LVR V G+ YA+KVLKK ++++ + ER +L V
Sbjct: 59 FELLKVLGQGSYGKVFLVRKVKGSDAGQLYAMKVLKK-ATLKVRDRVRSKMERDILAEVN 117
Query: 119 HPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLALEYLHS 178
HPF++++ FQ L++++D++ GG+LF+ L K F KFY AE+ LAL++LHS
Sbjct: 118 HPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLHS 177
Query: 179 HNIIYRDLKPENILLDRNGHIKITDFGFAKEVI---TVTWTLCGTPDYIAPEVITTKPYN 235
IIYRDLKPENILLD GHIKITDFG +KE I ++ CGT +Y+APEV+ + +
Sbjct: 178 LGIIYRDLKPENILLDEEGHIKITDFGLSKEAIDHDKRAYSFCGTIEYMAPEVVNRRGHT 237
Query: 236 KSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFFHPDVVDLLGKLITAD 295
+S DWWS G+L+FEML G PF +T IL ++ P F + LL L +
Sbjct: 238 QSADWWSFGVLMFEMLTGSLPFQGKDRKETMALILKAKLGMPQFLSGEAQSLLRALFKRN 297
Query: 296 LTRRLGNLQSGPDDIKSHPWFAEVIWEKLVAKDIETPYEPPI 337
RLG G ++IK HP+F + W L K+I+ P++P +
Sbjct: 298 PCNRLGAGIDGVEEIKRHPFFVTIDWNTLYRKEIKPPFKPAV 339
Score = 128 bits (322), Expect = 1e-29
Identities = 84/270 (31%), Positives = 142/270 (52%), Gaps = 29/270 (10%)
Query: 62 FQIMRTLGTGSFGRVHLVRSVHNGR--YYAIKVLKKHQIIRMKQIEHTNDERRMLKLVEH 119
++I +G GS+ R VH YA+K++ K + ++IE +L+ +H
Sbjct: 415 YEIKEDIGVGSYSVCK--RCVHKATDTEYAVKIIDKSKRDPSEEIEI------LLRYGQH 466
Query: 120 PFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLALEYLHSH 179
P +I + + D + +++VM+ + GGEL + + + F A +T ++YLHS
Sbjct: 467 PNIITLKDVYDDGKFVYLVMELMRGGELLDRILRQRYFSEREASDVLCTITKTMDYLHSQ 526
Query: 180 NIIYRDLKPENILL-DRNG---HIKITDFGFAKEVIT---VTWTLCGTPDYIAPEVITTK 232
+++RDLKP NIL D +G I++ DFGFAK++ + T C T +++APEV+ +
Sbjct: 527 GVVHRDLKPSNILYRDESGSPESIRVCDFGFAKQLRAGNGLLMTPCYTANFVAPEVLKRQ 586
Query: 233 PYNKSVDWWSLGILIFEMLAGYTPFY---DVTPMKTYEKILAGEVVYP----PFFHPDVV 285
Y+ + D WSLGIL++ MLAG+TPF D TP + +I +G+
Sbjct: 587 GYDAACDIWSLGILLYTMLAGFTPFANGPDDTPEEILARIGSGKYALSGGNWDSISDAAK 646
Query: 286 DLLGKLITADLTRRLGNLQSGPDDIKSHPW 315
D++ K++ D +RL +Q + HPW
Sbjct: 647 DVVSKMLHVDPHQRLTAMQ-----VLKHPW 671
>Hs4506073 [T] KOG0694 Serine/threonine protein kinase
Length = 942
Score = 230 bits (587), Expect = 2e-60
Identities = 121/306 (39%), Positives = 183/306 (59%), Gaps = 8/306 (2%)
Query: 50 STVSKGKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTND 109
S + K TL DF+ + LG G FG+V L +G +AIK LKK I+ ++E
Sbjct: 603 SPLRKSPLTLEDFKFLAVLGRGHFGKVLLSEFRPSGELFAIKALKKGDIVARDEVESLMC 662
Query: 110 ERRMLKLVE---HPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYA 166
E+R+L V HPFL+ ++G FQ ++ VM+Y GG+L + S F P A FY+
Sbjct: 663 EKRILAAVTSAGHPFLVNLFGCFQTPEHVCFVMEYSAGGDLMLHIH-SDVFSEPRAIFYS 721
Query: 167 AEVTLALEYLHSHNIIYRDLKPENILLDRNGHIKITDFGFAKEVITV---TWTLCGTPDY 223
A V L L++LH H I+YRDLK +N+LLD G++KI DFG KE + T T CGTP++
Sbjct: 722 ACVVLGLQFLHEHKIVYRDLKLDNLLLDTEGYVKIADFGLCKEGMGYGDRTSTFCGTPEF 781
Query: 224 IAPEVITTKPYNKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFFHPD 283
+APEV+T Y ++VDWW LG+L++EML G +PF + ++ I+ EV YP F +
Sbjct: 782 LAPEVLTDTSYTRAVDWWGLGVLLYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSAE 841
Query: 284 VVDLLGKLITADLTRRLGNLQSGPDDIKSHPWFAEVIWEKLVAKDIETPYEPPIAVGVGD 343
+ ++ +L+ + RRLG+ + +D+K P+F + WE L+A+ + P+ P ++ G D
Sbjct: 842 AIGIMRRLLRRNPERRLGSSERDAEDVKKQPFFRTLGWEALLARRLPPPFVPTLS-GRTD 900
Query: 344 SSLFDQ 349
S FD+
Sbjct: 901 VSNFDE 906
>Hs14758219 [T] KOG0694 Serine/threonine protein kinase
Length = 942
Score = 230 bits (587), Expect = 2e-60
Identities = 121/306 (39%), Positives = 183/306 (59%), Gaps = 8/306 (2%)
Query: 50 STVSKGKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTND 109
S + K TL DF+ + LG G FG+V L +G +AIK LKK I+ ++E
Sbjct: 603 SPLRKSPLTLEDFKFLAVLGRGHFGKVLLSEFRPSGELFAIKALKKGDIVARDEVESLMC 662
Query: 110 ERRMLKLVE---HPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYA 166
E+R+L V HPFL+ ++G FQ ++ VM+Y GG+L + S F P A FY+
Sbjct: 663 EKRILAAVTSAGHPFLVNLFGCFQTPEHVCFVMEYSAGGDLMLHIH-SDVFSEPRAIFYS 721
Query: 167 AEVTLALEYLHSHNIIYRDLKPENILLDRNGHIKITDFGFAKEVITV---TWTLCGTPDY 223
A V L L++LH H I+YRDLK +N+LLD G++KI DFG KE + T T CGTP++
Sbjct: 722 ACVVLGLQFLHEHKIVYRDLKLDNLLLDTEGYVKIADFGLCKEGMGYGDRTSTFCGTPEF 781
Query: 224 IAPEVITTKPYNKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFFHPD 283
+APEV+T Y ++VDWW LG+L++EML G +PF + ++ I+ EV YP F +
Sbjct: 782 LAPEVLTDTSYTRAVDWWGLGVLLYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSAE 841
Query: 284 VVDLLGKLITADLTRRLGNLQSGPDDIKSHPWFAEVIWEKLVAKDIETPYEPPIAVGVGD 343
+ ++ +L+ + RRLG+ + +D+K P+F + WE L+A+ + P+ P ++ G D
Sbjct: 842 AIGIMRRLLRRNPERRLGSSERDAEDVKKQPFFRTLGWEALLARRLPPPFVPTLS-GRTD 900
Query: 344 SSLFDQ 349
S FD+
Sbjct: 901 VSNFDE 906
>At3g08720 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 471
Score = 230 bits (587), Expect = 2e-60
Identities = 109/286 (38%), Positives = 181/286 (63%), Gaps = 3/286 (1%)
Query: 55 GKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRML 114
G + DF++++ +G G+FG+V+ VR YA+KV++K +I+ E+ ER +L
Sbjct: 133 GVVGIEDFEVLKVVGQGAFGKVYQVRKKDTSEIYAMKVMRKDKIVEKNHAEYMKAERDIL 192
Query: 115 KLVEHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLALE 174
++HPF++++ +FQ L++V+D+I GG LF L F +A+ Y AE+ A+
Sbjct: 193 TKIDHPFIVQLKYSFQTKYRLYLVLDFINGGHLFFQLYHQGLFREDLARVYTAEIVSAVS 252
Query: 175 YLHSHNIIYRDLKPENILLDRNGHIKITDFGFAKEV--ITVTWTLCGTPDYIAPEVITTK 232
+LH I++RDLKPENIL+D +GH+ +TDFG AKE T + ++CGT +Y+APE++ K
Sbjct: 253 HLHEKGIMHRDLKPENILMDVDGHVMLTDFGLAKEFEENTRSNSMCGTTEYMAPEIVRGK 312
Query: 233 PYNKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFFHPDVVDLLGKLI 292
++K+ DWWS+GIL++EML G PF + K +KI+ ++ P F + LL L+
Sbjct: 313 GHDKAADWWSVGILLYEMLTGKPPFLG-SKGKIQQKIVKDKIKLPQFLSNEAHALLKGLL 371
Query: 293 TADLTRRLGNLQSGPDDIKSHPWFAEVIWEKLVAKDIETPYEPPIA 338
+ RRLG+ SG ++IK H WF + W+KL A++++ ++P ++
Sbjct: 372 QKEPERRLGSGPSGAEEIKKHKWFKAINWKKLEAREVQPSFKPAVS 417
>Hs13384594 [T] KOG0696 Serine/threonine protein kinase
Length = 697
Score = 228 bits (582), Expect = 8e-60
Identities = 120/292 (41%), Positives = 171/292 (58%), Gaps = 9/292 (3%)
Query: 53 SKGKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERR 112
S G+ + DF + LG GSFG+V L + YAIK+LKK I++ ++ T E+R
Sbjct: 342 SPGRLHISDFSFLMVLGKGSFGKVMLAERRGSDELYAIKILKKDVIVQDDDVDCTLVEKR 401
Query: 113 MLKLVEHP------FLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYA 166
+L L FL ++ TFQ L+ VM+Y+ GG+L +++ +F P A FYA
Sbjct: 402 VLALGGRGPGGRPHFLTQLHSTFQTPDRLYFVMEYVTGGDLMYHIQQLGKFKEPHAAFYA 461
Query: 167 AEVTLALEYLHSHNIIYRDLKPENILLDRNGHIKITDFGFAKEVI---TVTWTLCGTPDY 223
AE+ + L +LH+ IIYRDLK +N++LD GHIKITDFG KE + T T T CGTPDY
Sbjct: 462 AEIAIGLFFLHNQGIIYRDLKLDNVMLDAEGHIKITDFGMCKENVFPGTTTRTFCGTPDY 521
Query: 224 IAPEVITTKPYNKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFFHPD 283
IAPE+I +PY KSVDWWS G+L++EMLAG PF + ++ I+ V YP +
Sbjct: 522 IAPEIIAYQPYGKSVDWWSFGVLLYEMLAGQPPFDGEDEEELFQAIMEQTVTYPKSLSRE 581
Query: 284 VVDLLGKLITADLTRRLGNLQSGPDDIKSHPWFAEVIWEKLVAKDIETPYEP 335
V + +T +RLG+ G I++H +F + WE+L +I P+ P
Sbjct: 582 AVAICKGFLTKHPGKRLGSGPDGEPTIRAHGFFRWIDWERLERLEIPPPFRP 633
>7295638 [T] KOG0603 Ribosomal protein S6 kinase
Length = 911
Score = 228 bits (582), Expect = 8e-60
Identities = 126/322 (39%), Positives = 188/322 (58%), Gaps = 8/322 (2%)
Query: 32 QSTDYLLAQQKESLLPQRSTVSKGKYTLHDFQIMRTLGTGSFGRVHLVRSVHN---GRYY 88
+ T+ L + E L + K F+++R LG GSFG+V LVR + G Y
Sbjct: 169 EDTEPLYETENEFELKEVIKEGHDKADPSQFELLRVLGEGSFGKVFLVRKIIGKDAGTLY 228
Query: 89 AIKVLKKHQIIRMKQIEHTNDERRMLKLVEHPFLIRMWGTFQDSRNLFMVMDYIEGGELF 148
A+KVLKK + ++ TN ER++L V H F++R+ FQ L++++D++ GG+LF
Sbjct: 229 AMKVLKKATLKVKDRVRSTN-ERKILADVGHAFIVRLHYAFQTPGKLYLILDFLRGGDLF 287
Query: 149 SLLRKSQRFPNPVAKFYAAEVTLALEYLHSHNIIYRDLKPENILLDRNGHIKITDFGFAK 208
+ L K F KFY AE+ LA+ +LH+ IIYRDLKPENILLD +GHI +TDFG +K
Sbjct: 288 TRLSKEVMFTEEDVKFYLAELALAMNHLHTLGIIYRDLKPENILLDEHGHIALTDFGLSK 347
Query: 209 EVI--TVTWTLCGTPDYIAPEVITTKPYNKSVDWWSLGILIFEMLAGYTPFYDVTPMKTY 266
+ + + T++ CGT +Y+APE++ K ++ + DWWS G+L++EML G PF+ T +T
Sbjct: 348 QPLDGSKTYSFCGTVEYMAPEIVNRKGHDFAADWWSFGVLMYEMLTGNLPFHGQTRQETM 407
Query: 267 EKILAGEVVYPPFFHPDVVDLLGKLITADLTRRLGNLQSGPDDIKSHPWFAEVIWEKLVA 326
+IL ++ P P+ LL L + RLG G DIK+H +FA + W +L
Sbjct: 408 NQILRSKLGMPENLSPEAQSLLRALFKRNPQNRLGAGAQGILDIKAHCFFATIDWVRLER 467
Query: 327 KDIETPYEPPIAVGVGDSSLFD 348
K + P+ P AV D+ FD
Sbjct: 468 KQVRPPFIP--AVSRDDAFYFD 487
Score = 113 bits (283), Expect = 4e-25
Identities = 63/220 (28%), Positives = 119/220 (53%), Gaps = 11/220 (5%)
Query: 61 DFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTN---DERRMLKLV 117
++ +++ LG G+F L + ++YA+KV++K + + + ML+
Sbjct: 567 EYNLLQELGRGTFSVCRLCEHRASKKHYAVKVIEKAAVAAASTSTSADCWEEVEIMLRYG 626
Query: 118 EHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLALEYLH 177
HP ++ ++ ++D+ + ++VM+ ++GGEL + + A + A+ YLH
Sbjct: 627 NHPNIVTLYSVYEDAGSAYLVMELLKGGELLDRILAVGQMCESEASAVLRTIASAVAYLH 686
Query: 178 SHNIIYRDLKPENILL----DRNGHIKITDFGFAKEVIT---VTWTLCGTPDYIAPEVIT 230
H +++RDLKP N++ +K+ D GFAK++ + T C T +++APEV+
Sbjct: 687 EHGVVHRDLKPSNMIYASMRQTPETLKLCDLGFAKQLRADNGLLMTPCYTANFVAPEVLK 746
Query: 231 TKPYNKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKIL 270
+ Y+ + D WSLG+L++ ML+G TPF TP + + IL
Sbjct: 747 RQGYDLACDIWSLGVLLYIMLSGRTPFAS-TPNDSPDVIL 785
>At3g08730 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 465
Score = 228 bits (581), Expect = 1e-59
Identities = 109/286 (38%), Positives = 179/286 (62%), Gaps = 3/286 (1%)
Query: 55 GKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRML 114
G + DF++M+ +G G+FG+V+ VR YA+KV++K I+ E+ ER +L
Sbjct: 127 GVVGIDDFEVMKVVGKGAFGKVYQVRKKETSEIYAMKVMRKDHIMEKNHAEYMKAERDIL 186
Query: 115 KLVEHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLALE 174
++HPF++++ +FQ L++V+D+I GG LF L F +A+ Y AE+ A+
Sbjct: 187 TKIDHPFIVQLKYSFQTKYRLYLVLDFINGGHLFFQLYHQGLFREDLARVYTAEIVSAVS 246
Query: 175 YLHSHNIIYRDLKPENILLDRNGHIKITDFGFAKEV--ITVTWTLCGTPDYIAPEVITTK 232
+LH I++RDLKPENIL+D +GH+ +TDFG AKE T + ++CGT +Y+APE++ K
Sbjct: 247 HLHEKGIMHRDLKPENILMDTDGHVMLTDFGLAKEFEENTRSNSMCGTTEYMAPEIVRGK 306
Query: 233 PYNKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFFHPDVVDLLGKLI 292
++K+ DWWS+GIL++EML G PF + K +KI+ ++ P F + +L L+
Sbjct: 307 GHDKAADWWSVGILLYEMLTGKPPFLG-SKGKIQQKIVKDKIKLPQFLSNEAHAILKGLL 365
Query: 293 TADLTRRLGNLQSGPDDIKSHPWFAEVIWEKLVAKDIETPYEPPIA 338
+ RRLG+ SG ++IK H WF + W+KL A+++ ++P ++
Sbjct: 366 QKEPERRLGSGLSGAEEIKQHKWFKGINWKKLEAREVMPSFKPEVS 411
>7303915 [T] KOG0694 Serine/threonine protein kinase
Length = 590
Score = 228 bits (581), Expect = 1e-59
Identities = 117/301 (38%), Positives = 184/301 (60%), Gaps = 8/301 (2%)
Query: 55 GKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRML 114
G ++ +F+++ LG G FG+V L + N +YYAIK LKK II ++E E+R+
Sbjct: 256 GMLSMDNFRLLSVLGRGHFGKVILSQLRSNNQYYAIKALKKGDIIARDEVESLLSEKRIF 315
Query: 115 KL---VEHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTL 171
++ + HPFL+ ++ FQ +++ VM+Y GG+L + + F P A FYAA V L
Sbjct: 316 EVANAMRHPFLVNLYSCFQTEQHVCFVMEYAAGGDLMMHIH-TDVFLEPRAVFYAACVVL 374
Query: 172 ALEYLHSHNIIYRDLKPENILLDRNGHIKITDFGFAKEVITV---TWTLCGTPDYIAPEV 228
L+YLH + IIYRDLK +N+LLD G++KI DFG KE + T T CGTP+++APEV
Sbjct: 375 GLQYLHENKIIYRDLKLDNLLLDTEGYVKIADFGLCKEGMGFGDRTGTFCGTPEFLAPEV 434
Query: 229 ITTKPYNKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFFHPDVVDLL 288
+T Y ++VDWW LG+LIFEML G +PF + ++ I+ EV YP F + + ++
Sbjct: 435 LTETSYTRAVDWWGLGVLIFEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSLEAIAVM 494
Query: 289 GKLITADLTRRLGNLQSGPDDIKSHPWFAEVIWEKLVAKDIETPYEPPIAVGVGDSSLFD 348
+L+ + RRLG+ + +D+K +F ++W+ L+ + ++ P+ P I + D S FD
Sbjct: 495 RRLLRKNPERRLGSSERDAEDVKKQAFFRSIVWDDLLLRKVKPPFVPTIN-HLEDVSNFD 553
Query: 349 Q 349
+
Sbjct: 554 E 554
>7303914 [T] KOG0694 Serine/threonine protein kinase
Length = 1284
Score = 228 bits (581), Expect = 1e-59
Identities = 117/301 (38%), Positives = 184/301 (60%), Gaps = 8/301 (2%)
Query: 55 GKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRML 114
G ++ +F+++ LG G FG+V L + N +YYAIK LKK II ++E E+R+
Sbjct: 950 GMLSMDNFRLLSVLGRGHFGKVILSQLRSNNQYYAIKALKKGDIIARDEVESLLSEKRIF 1009
Query: 115 KL---VEHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTL 171
++ + HPFL+ ++ FQ +++ VM+Y GG+L + + F P A FYAA V L
Sbjct: 1010 EVANAMRHPFLVNLYSCFQTEQHVCFVMEYAAGGDLMMHIH-TDVFLEPRAVFYAACVVL 1068
Query: 172 ALEYLHSHNIIYRDLKPENILLDRNGHIKITDFGFAKEVITV---TWTLCGTPDYIAPEV 228
L+YLH + IIYRDLK +N+LLD G++KI DFG KE + T T CGTP+++APEV
Sbjct: 1069 GLQYLHENKIIYRDLKLDNLLLDTEGYVKIADFGLCKEGMGFGDRTGTFCGTPEFLAPEV 1128
Query: 229 ITTKPYNKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFFHPDVVDLL 288
+T Y ++VDWW LG+LIFEML G +PF + ++ I+ EV YP F + + ++
Sbjct: 1129 LTETSYTRAVDWWGLGVLIFEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSLEAIAVM 1188
Query: 289 GKLITADLTRRLGNLQSGPDDIKSHPWFAEVIWEKLVAKDIETPYEPPIAVGVGDSSLFD 348
+L+ + RRLG+ + +D+K +F ++W+ L+ + ++ P+ P I + D S FD
Sbjct: 1189 RRLLRKNPERRLGSSERDAEDVKKQAFFRSIVWDDLLLRKVKPPFVPTIN-HLEDVSNFD 1247
Query: 349 Q 349
+
Sbjct: 1248 E 1248
>Hs5453974 [T] KOG0694 Serine/threonine protein kinase
Length = 984
Score = 227 bits (578), Expect = 2e-59
Identities = 119/309 (38%), Positives = 178/309 (57%), Gaps = 8/309 (2%)
Query: 46 LPQRSTVSKGKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIE 105
L R + + ++ L DF+ LG G FG+V L + +AIK LKK I+ +++
Sbjct: 641 LEDRRSQQRFQFNLQDFRCCAVLGRGHFGKVLLAEYKNTNEMFAIKALKKGDIVARDEVD 700
Query: 106 HTNDERRMLKLVE---HPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVA 162
E+R+ + V HPFL+ ++ FQ ++ VM+Y GG+L + + F P A
Sbjct: 701 SLMCEKRIFETVNSVRHPFLVNLFACFQTKEHVCFVMEYAAGGDLMMHIH-TDVFSEPRA 759
Query: 163 KFYAAEVTLALEYLHSHNIIYRDLKPENILLDRNGHIKITDFGFAKEVITV---TWTLCG 219
FYAA V L L+YLH H I+YRDLK +N+LLD G +KI DFG KE + T T CG
Sbjct: 760 VFYAACVVLGLQYLHEHKIVYRDLKLDNLLLDTEGFVKIADFGLCKEGMGYGDRTSTFCG 819
Query: 220 TPDYIAPEVITTKPYNKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPF 279
TP+++APEV+T Y ++VDWW LG+LI+EML G +PF + ++ I+ EV YP F
Sbjct: 820 TPEFLAPEVLTETSYTRAVDWWGLGVLIYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRF 879
Query: 280 FHPDVVDLLGKLITADLTRRLGNLQSGPDDIKSHPWFAEVIWEKLVAKDIETPYEPPIAV 339
+ + ++ +L+ + RRLG + +D+K HP+F + W L+ K ++ P+ P I
Sbjct: 880 LSTEAISIMRRLLRRNPERRLGASEKDAEDVKKHPFFRLIDWSALMDKKVKPPFIPTIR- 938
Query: 340 GVGDSSLFD 348
G D S FD
Sbjct: 939 GREDVSNFD 947
>Hs4506071 [T] KOG0695 Serine/threonine protein kinase
Length = 587
Score = 227 bits (578), Expect = 2e-59
Identities = 122/340 (35%), Positives = 191/340 (55%), Gaps = 14/340 (4%)
Query: 38 LAQQKESLLPQRSTVSKGKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQ 97
+ ++KE++ + S + L DF ++R +G GS+ +V LVR R YA+KV+KK
Sbjct: 221 VGEEKEAMNTRESGKASSSLGLQDFDLLRVIGRGSYAKVLLVRLKKTDRIYAMKVVKKEL 280
Query: 98 IIRMKQIEHTNDERRMLKLVE-HPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQR 156
+ + I+ E+ + + HPFL+ + FQ LF V++Y+ GG+L +++ ++
Sbjct: 281 VNDDEDIDWVQTEKHVFEQASNHPFLVGLHSCFQTESRLFFVIEYVNGGDLMFHMQRQRK 340
Query: 157 FPNPVAKFYAAEVTLALEYLHSHNIIYRDLKPENILLDRNGHIKITDFGFAKEVI---TV 213
P A+FY+AE++LAL YLH IIYRDLK +N+LLD GHIK+TD+G KE +
Sbjct: 341 LPEEHARFYSAEISLALNYLHERGIIYRDLKLDNVLLDSEGHIKLTDYGMCKEGLRPGDT 400
Query: 214 TWTLCGTPDYIAPEVITTKPYNKSVDWWSLGILIFEMLAGYTPFYDV---------TPMK 264
T T CGTP+YIAPE++ + Y SVDWW+LG+L+FEM+AG +PF V T
Sbjct: 401 TSTFCGTPNYIAPEILRGEDYGFSVDWWALGVLMFEMMAGRSPFDIVGSSDNPDQNTEDY 460
Query: 265 TYEKILAGEVVYPPFFHPDVVDLLGKLITADLTRRLG-NLQSGPDDIKSHPWFAEVIWEK 323
++ IL ++ P +L + D RLG + Q+G DI+ HP+F V W+
Sbjct: 461 LFQVILEKQIRIPRSLSVKAASVLKSFLNKDPKERLGCHPQTGFADIQGHPFFRNVDWDM 520
Query: 324 LVAKDIETPYEPPIAVGVGDSSLFDQYPEEQLDYGVQGED 363
+ K + P++P I+ G + Q+ E + +D
Sbjct: 521 MEQKQVVPPFKPNISGEFGLDNFDSQFTNEPVQLTPDDDD 560
>7302861 [T] KOG0696 Serine/threonine protein kinase
Length = 700
Score = 226 bits (575), Expect = 5e-59
Identities = 118/300 (39%), Positives = 175/300 (58%), Gaps = 4/300 (1%)
Query: 61 DFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRMLKLVEHP 120
DF ++ +G GSFG+V L YA+KVL+K II+ +E +E+++L L P
Sbjct: 370 DFNFVKVIGKGSFGKVLLAERRGTDELYAVKVLRKDVIIQTDDMELPMNEKKILALSGRP 429
Query: 121 -FLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLALEYLHSH 179
FL+ M FQ LF VM+Y +GG+L +++ RF VA FYA EV +AL +LH
Sbjct: 430 PFLVSMHSCFQTMDRLFFVMEYCKGGDLMYHMQQYGRFKESVAIFYAVEVAIALFFLHER 489
Query: 180 NIIYRDLKPENILLDRNGHIKITDFGFAKEVIT---VTWTLCGTPDYIAPEVITTKPYNK 236
+IIYRDLK +NILLD GH+K+ DFG +KE +T T T CGTP+Y+APE+++ PY+
Sbjct: 490 DIIYRDLKLDNILLDGEGHVKLVDFGLSKEGVTERQTTRTFCGTPNYMAPEIVSYDPYSI 549
Query: 237 SVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFFHPDVVDLLGKLITADL 296
+ DWWS G+L+FE +AG PF + I + V+P F + +D++ +T
Sbjct: 550 AADWWSFGVLLFEFMAGQAPFEGDDETTVFRNIKDKKAVFPKHFSVEAMDIITSFLTKKP 609
Query: 297 TRRLGNLQSGPDDIKSHPWFAEVIWEKLVAKDIETPYEPPIAVGVGDSSLFDQYPEEQLD 356
RLG + +I +HP+F V W+K A ++E P +P I S+ D + +E+ D
Sbjct: 610 NNRLGAGRYARQEITTHPFFRNVDWDKAEACEMEPPIKPMIKHRKDISNFDDAFTKEKTD 669
>Hs7657526 [T] KOG0603 Ribosomal protein S6 kinase
Length = 745
Score = 224 bits (571), Expect = 2e-58
Identities = 114/280 (40%), Positives = 174/280 (61%), Gaps = 9/280 (3%)
Query: 62 FQIMRTLGTGSFGRVHLVRSVHN---GRYYAIKVLKKHQIIRMKQIEHTNDERRMLKLVE 118
F++++ LG GSFG+V LVR G+ YA+KVLKK + +++ T ER +L V
Sbjct: 73 FELLKVLGQGSFGKVFLVRKKTGPDAGQLYAMKVLKKASL-KVRDRVRTKMERDILVEVN 131
Query: 119 HPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLALEYLHS 178
HPF++++ FQ L++++D++ GG++F+ L K F KFY AE+ LAL++LH
Sbjct: 132 HPFIVKLHYAFQTEGKLYLILDFLRGGDVFTRLSKEVLFTEEDVKFYLAELALALDHLHQ 191
Query: 179 HNIIYRDLKPENILLDRNGHIKITDFGFAKEVI---TVTWTLCGTPDYIAPEVITTKPYN 235
I+YRDLKPENILLD GHIK+TDFG +KE + ++ CGT +Y+APEV+ + ++
Sbjct: 192 LGIVYRDLKPENILLDEIGHIKLTDFGLSKESVDQEKKAYSFCGTVEYMAPEVVNRRGHS 251
Query: 236 KSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFFHPDVVDLLGKLITAD 295
+S DWWS G+L+FEML G PF +T IL ++ P F + LL L +
Sbjct: 252 QSADWWSYGVLMFEMLTGTLPFQGKDRNETMNMILKAKLGMPQFLSAEAQSLLRMLFKRN 311
Query: 296 LTRRLGNLQSGPDDIKSHPWFAEVIWEKLVAKDIETPYEP 335
RLG+ G ++IK H +FA + W+KL ++++ P++P
Sbjct: 312 PANRLGS--EGVEEIKRHLFFANIDWDKLYKREVQPPFKP 349
Score = 117 bits (293), Expect = 3e-26
Identities = 70/216 (32%), Positives = 119/216 (54%), Gaps = 14/216 (6%)
Query: 62 FQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRMLKLVEHPF 121
+++ +G GS+ +A+K++ K + ++IE +++ +HP
Sbjct: 426 YELKEDIGVGSYSVCKRCIHATTNMEFAVKIIDKSKRDPSEEIEI------LMRYGQHPN 479
Query: 122 LIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLALEYLHSHNI 181
+I + F D R +++V D ++GGEL + K + F A ++ ++YLH +
Sbjct: 480 IITLKDVFDDGRYVYLVTDLMKGGELLDRILKQKCFSEREASDILYVISKTVDYLHCQGV 539
Query: 182 IYRDLKPENIL-LDRNG---HIKITDFGFAKEV---ITVTWTLCGTPDYIAPEVITTKPY 234
++RDLKP NIL +D + I+I DFGFAK++ + T C T +++APEV+ + Y
Sbjct: 540 VHRDLKPSNILYMDESASADSIRICDFGFAKQLRGENGLLLTPCYTANFVAPEVLMQQGY 599
Query: 235 NKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKIL 270
+ + D WSLG+L + MLAGYTPF + P T E+IL
Sbjct: 600 DAACDIWSLGVLFYTMLAGYTPFAN-GPNDTPEEIL 634
>Hs4759052 [T] KOG0603 Ribosomal protein S6 kinase
Length = 809
Score = 223 bits (569), Expect = 3e-58
Identities = 123/331 (37%), Positives = 193/331 (58%), Gaps = 15/331 (4%)
Query: 42 KESLLPQRSTVSKGKYTLHDFQIMRTLGTGSFGRVHLVRSVHN---GRYYAIKVLKKHQI 98
K L T K + +F++++ LGTG++G+V LVR + G+ YA+KVLKK I
Sbjct: 29 KHELRTANLTGHAEKVGIENFELLKVLGTGAYGKVFLVRKISGHDTGKLYAMKVLKKATI 88
Query: 99 I-RMKQIEHTNDERRMLKLV-EHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQR 156
+ + K EHT ER++L+ + + PFL+ + FQ L +++DYI GGELF+ L + +R
Sbjct: 89 VQKAKTTEHTRTERQVLEHIRQSPFLVTLHYAFQTETKLHLILDYINGGELFTHLSQRER 148
Query: 157 FPNPVAKFYAAEVTLALEYLHSHNIIYRDLKPENILLDRNGHIKITDFGFAKEVIT---- 212
F + Y E+ LALE+LH IIYRD+K ENILLD NGH+ +TDFG +KE +
Sbjct: 149 FTEHEVQIYVGEIVLALEHLHKLGIIYRDIKLENILLDSNGHVVLTDFGLSKEFVADETE 208
Query: 213 VTWTLCGTPDYIAPEVIT--TKPYNKSVDWWSLGILIFEMLAGYTPF----YDVTPMKTY 266
++ CGT +Y+AP+++ ++K+VDWWSLG+L++E+L G +PF + +
Sbjct: 209 RAYSFCGTIEYMAPDIVRGGDSGHDKAVDWWSLGVLMYELLTGASPFTVDGEKNSQAEIS 268
Query: 267 EKILAGEVVYPPFFHPDVVDLLGKLITADLTRRLGNLQSGPDDIKSHPWFAEVIWEKLVA 326
+IL E YP DL+ +L+ D +RLG D+IK H +F ++ W+ L A
Sbjct: 269 RRILKSEPPYPQEMSALAKDLIQRLLMKDPKKRLGCGPRDADEIKEHLFFQKINWDDLAA 328
Query: 327 KDIETPYEPPIAVGVGDSSLFDQYPEEQLDY 357
K + P++P I + S+ +++ E Y
Sbjct: 329 KKVPAPFKPVIRDELDVSNFAEEFTEMDPTY 359
Score = 117 bits (293), Expect = 3e-26
Identities = 81/253 (32%), Positives = 127/253 (50%), Gaps = 24/253 (9%)
Query: 66 RTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRMLKLVE-HPFLIR 124
+ LG GSF + VH A++V +II + +T E LKL E HP +++
Sbjct: 430 KPLGEGSFSICR--KCVHKKSNQALQV----KIISKRMEANTQKEITALKLCEGHPNIVK 483
Query: 125 MWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLALEYLHSHNIIYR 184
+ F D + F+VM+ + GGELF LRK + F A + ++ AL ++H +++R
Sbjct: 484 LHEVFHDQLHTFLVMELLNGGELFDALRKKKHFSETEASYIMRKLVSALSHMHDLGVVHR 543
Query: 185 DLKPENILL---DRNGHIKITDFGFAKEVITVTWTL---CGTPDYIAPEVITTKPYNKSV 238
DLKPEN+L + N IKI DFGFA+ L C T PE++ Y++S
Sbjct: 544 DLKPENLLFTDENDNLEIKIIDFGFARLKPPDNQPLKTPCFTLHSCRPELLNQNGYDESC 603
Query: 239 DWWSLGILIFEMLAGYTPFYD-------VTPMKTYEKILAGEVVYP----PFFHPDVVDL 287
D WSLG++++ ML+G PF + ++ +KI G+ + + DL
Sbjct: 604 DLWSLGVILYTMLSGQVPFQSHDRSLTCTSAVEIMKKIKKGDFSFEGEAWKNVSQEAKDL 663
Query: 288 LGKLITADLTRRL 300
+ L+T D +RL
Sbjct: 664 IQGLLTVDPNKRL 676
>SPCC4G3.08 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 436
Score = 223 bits (567), Expect = 5e-58
Identities = 122/291 (41%), Positives = 171/291 (57%), Gaps = 5/291 (1%)
Query: 52 VSKGKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQII-RMKQIEHTNDE 110
V GK DFQ + LG GS+G+V LV+ + GR +A K LKK I+ R K +E T +E
Sbjct: 81 VPSGKMRPADFQPLTVLGRGSYGKVLLVKQKNTGRLFAQKQLKKASIVLRAKGLEQTKNE 140
Query: 111 RRMLKLVEHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVT 170
R++L+ V HPF+ R++ FQD L++++ Y GGELFS L + + P V FY AE+T
Sbjct: 141 RQILEEVRHPFICRLYYAFQDHDRLYLILQYAPGGELFSHLAEQRMLPEDVVAFYTAELT 200
Query: 171 LALEYLHSHNIIYRDLKPENILLDRNGHIKITDFGFAK--EVITVTWTLCGTPDYIAPEV 228
LAL +LH I+YRDLKPEN LLD GHI +TDFG +K E + GT +Y APE+
Sbjct: 201 LALIHLHKLGIVYRDLKPENCLLDAEGHILLTDFGLSKVAENGADCRSFVGTEEYCAPEI 260
Query: 229 ITTKPYNKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFFHPDVVDLL 288
+ +PY+ +VDWWS+GILIF++L G PF + EKI + P + D D++
Sbjct: 261 LLEQPYDHAVDWWSMGILIFDLLTGSPPFTANNHKRIMEKITRAKPNIPFYVTSDARDII 320
Query: 289 GKLITADLTRRLG--NLQSGPDDIKSHPWFAEVIWEKLVAKDIETPYEPPI 337
K + + +RLG + G D IK H + + W KL + + P P I
Sbjct: 321 NKFLKKNPKQRLGADGPEKGYDAIKKHRIYRRIDWNKLEKRMLPPPIVPCI 371
>Hs20535816 [T] KOG0695 Serine/threonine protein kinase
Length = 592
Score = 221 bits (564), Expect = 1e-57
Identities = 121/317 (38%), Positives = 183/317 (57%), Gaps = 12/317 (3%)
Query: 59 LHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRMLKLVE 118
L DF ++R +G GS+ +V LVR N + YA+KV+KK + + I+ E+ + +
Sbjct: 249 LQDFDLIRVIGRGSYAKVLLVRLKKNDQIYAMKVVKKELVHDDEDIDWVQTEKHVFEQAS 308
Query: 119 -HPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLALEYLH 177
+PFL+ + FQ + LF+V++Y+ GG+L +++ ++ P A+FYAAE+ +AL +LH
Sbjct: 309 SNPFLVGLHSCFQTTSRLFLVIEYVNGGDLMFHMQRQRKLPEEHARFYAAEICIALNFLH 368
Query: 178 SHNIIYRDLKPENILLDRNGHIKITDFGFAKEVI---TVTWTLCGTPDYIAPEVITTKPY 234
IIYRDLK +N+LLD +GHIK+TD+G KE + T T CGTP+YIAPE++ + Y
Sbjct: 369 ERGIIYRDLKLDNVLLDADGHIKLTDYGMCKEGLGPGDTTSTFCGTPNYIAPEILRGEEY 428
Query: 235 NKSVDWWSLGILIFEMLAGYTPFYDVT---PMKT----YEKILAGEVVYPPFFHPDVVDL 287
SVDWW+LG+L+FEM+AG +PF +T M T ++ IL + P F +
Sbjct: 429 GFSVDWWALGVLMFEMMAGRSPFDIITDNPDMNTEDYLFQVILEKPIRIPRFLSVKASHV 488
Query: 288 LGKLITADLTRRLG-NLQSGPDDIKSHPWFAEVIWEKLVAKDIETPYEPPIAVGVGDSSL 346
L + D RLG Q+G DIKSH +F + W+ L K P++P I G +
Sbjct: 489 LKGFLNKDPKERLGCRPQTGFSDIKSHAFFRSIDWDLLEKKQALPPFQPQITDDYGLDNF 548
Query: 347 FDQYPEEQLDYGVQGED 363
Q+ E + ED
Sbjct: 549 DTQFTSEPVQLTPDDED 565
>Hs10864650 [T] KOG0695 Serine/threonine protein kinase
Length = 592
Score = 221 bits (564), Expect = 1e-57
Identities = 121/317 (38%), Positives = 183/317 (57%), Gaps = 12/317 (3%)
Query: 59 LHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRMLKLVE 118
L DF ++R +G GS+ +V LVR N + YA+KV+KK + + I+ E+ + +
Sbjct: 249 LQDFDLIRVIGRGSYAKVLLVRLKKNDQIYAMKVVKKELVHDDEDIDWVQTEKHVFEQAS 308
Query: 119 -HPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLALEYLH 177
+PFL+ + FQ + LF+V++Y+ GG+L +++ ++ P A+FYAAE+ +AL +LH
Sbjct: 309 SNPFLVGLHSCFQTTSRLFLVIEYVNGGDLMFHMQRQRKLPEEHARFYAAEICIALNFLH 368
Query: 178 SHNIIYRDLKPENILLDRNGHIKITDFGFAKEVI---TVTWTLCGTPDYIAPEVITTKPY 234
IIYRDLK +N+LLD +GHIK+TD+G KE + T T CGTP+YIAPE++ + Y
Sbjct: 369 ERGIIYRDLKLDNVLLDADGHIKLTDYGMCKEGLGPGDTTSTFCGTPNYIAPEILRGEEY 428
Query: 235 NKSVDWWSLGILIFEMLAGYTPFYDVT---PMKT----YEKILAGEVVYPPFFHPDVVDL 287
SVDWW+LG+L+FEM+AG +PF +T M T ++ IL + P F +
Sbjct: 429 GFSVDWWALGVLMFEMMAGRSPFDIITDNPDMNTEDYLFQVILEKPIRIPRFLSVKASHV 488
Query: 288 LGKLITADLTRRLG-NLQSGPDDIKSHPWFAEVIWEKLVAKDIETPYEPPIAVGVGDSSL 346
L + D RLG Q+G DIKSH +F + W+ L K P++P I G +
Sbjct: 489 LKGFLNKDPKERLGCRPQTGFSDIKSHAFFRSIDWDLLEKKQALPPFQPQITDDYGLDNF 548
Query: 347 FDQYPEEQLDYGVQGED 363
Q+ E + ED
Sbjct: 549 DTQFTSEPVQLTPDDED 565
>Hs14735945 [T] KOG0694 Serine/threonine protein kinase
Length = 676
Score = 221 bits (563), Expect = 1e-57
Identities = 126/298 (42%), Positives = 174/298 (58%), Gaps = 9/298 (3%)
Query: 56 KYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRMLK 115
K +++F + LG GSFG+V L G Y+AIK LKK ++ +E T E+R+L
Sbjct: 343 KCNINNFIFHKVLGKGSFGKVLLGELKGRGEYFAIKALKKDVVLIDDDVECTMVEKRVLT 402
Query: 116 LV-EHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLALE 174
L E+PFL + TFQ +LF VM+++ GG+L ++ RF A FYAAE+ L+
Sbjct: 403 LAAENPFLTHLICTFQTKDHLFFVMEFLNGGDLMYHIQDKGRFELYRATFYAAEIMCGLQ 462
Query: 175 YLHSHNIIYRDLKPENILLDRNGHIKITDFGFAKEVI---TVTWTLCGTPDYIAPEVITT 231
+LHS IIYRDLK +N+LLDR+GHIKI DFG KE I + T CGTPDYIAPE++
Sbjct: 463 FLHSKGIIYRDLKLDNVLLDRDGHIKIADFGMCKENIFGESRASTFCGTPDYIAPEILQG 522
Query: 232 KPYNKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFFHPDVVDLLGKL 291
Y SVDWWS G+L++EML G +PF+ + +E I YP + + D+L KL
Sbjct: 523 LKYTFSVDWWSFGVLLYEMLIGQSPFHGDDEDELFESIRVDTPHYPRWITKESKDILEKL 582
Query: 292 ITADLTRRLGNLQSGPDDIKSHPWFAEVIWEKLVAKDIETPYEPPIAVGVGDSSLFDQ 349
+ T+RLG +IK HP+F + W L + +E P+ P + D S FDQ
Sbjct: 583 FEREPTKRLG----VTGNIKIHPFFKTINWTLLEKRRLEPPFRPKVK-SPRDYSNFDQ 635
>7301972 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 393
Score = 221 bits (562), Expect = 2e-57
Identities = 109/250 (43%), Positives = 162/250 (64%), Gaps = 3/250 (1%)
Query: 53 SKGKYT-LHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDER 111
++ YT L ++ LG GSFG V LVR YYA K++ K ++R+KQ+ H ++E+
Sbjct: 35 TQSPYTNLENYITRAVLGNGSFGTVMLVREKSGKNYYAAKMMSKEDLVRLKQVAHVHNEK 94
Query: 112 RMLKLVEHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTL 171
+L PFLI + + + L++++ + GGELFS R+ ++F A+FYAA+V L
Sbjct: 95 HVLNAARFPFLIYLVDSTKCFDYLYLILPLVNGGELFSYHRRVRKFNEKHARFYAAQVAL 154
Query: 172 ALEYLHSHNIIYRDLKPENILLDRNGHIKITDFGFAKEVITVTWTLCGTPDYIAPEVITT 231
ALEY+H +++YRDLKPENILLD+ G+IKITDFGF K V T TLCGTP+Y+APE++
Sbjct: 155 ALEYMHKMHLMYRDLKPENILLDQRGYIKITDFGFTKRVDGRTSTLCGTPEYLAPEIVQL 214
Query: 232 KPYNKSVDWWSLGILIFEMLAGYTPF--YDVTPMKTYEKILAGEVVYPPFFHPDVVDLLG 289
+PYNKSVDWW+ GIL++E +AG +PF ++ + Y KI + P +F + L+
Sbjct: 215 RPYNKSVDWWAFGILVYEFVAGRSPFAIHNRDVILMYSKICICDYKMPSYFTSQLRSLVE 274
Query: 290 KLITADLTRR 299
L+ D ++R
Sbjct: 275 SLMQVDTSKR 284
>Hs5453970 [T] KOG0694 Serine/threonine protein kinase
Length = 676
Score = 219 bits (559), Expect = 4e-57
Identities = 126/298 (42%), Positives = 173/298 (57%), Gaps = 9/298 (3%)
Query: 56 KYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRMLK 115
K +++F + LG GSFG+V L G Y AIK LKK ++ +E T E+R+L
Sbjct: 343 KCNINNFIFHKVLGKGSFGKVLLGELKGRGEYSAIKALKKDVVLIDDDVECTMVEKRVLT 402
Query: 116 LV-EHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLALE 174
L E+PFL + TFQ +LF VM+++ GG+L ++ RF A FYAAE+ L+
Sbjct: 403 LAAENPFLTHLICTFQTKDHLFFVMEFLNGGDLMYHIQDKGRFELYRATFYAAEIMCGLQ 462
Query: 175 YLHSHNIIYRDLKPENILLDRNGHIKITDFGFAKEVI---TVTWTLCGTPDYIAPEVITT 231
+LHS IIYRDLK +N+LLDR+GHIKI DFG KE I + T CGTPDYIAPE++
Sbjct: 463 FLHSKGIIYRDLKLDNVLLDRDGHIKIADFGMCKENIFGESRASTFCGTPDYIAPEILQG 522
Query: 232 KPYNKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFFHPDVVDLLGKL 291
Y SVDWWS G+L++EML G +PF+ + +E I YP + + D+L KL
Sbjct: 523 LKYTFSVDWWSFGVLLYEMLIGQSPFHGDDEDELFESIRVDTPHYPRWITKESKDILEKL 582
Query: 292 ITADLTRRLGNLQSGPDDIKSHPWFAEVIWEKLVAKDIETPYEPPIAVGVGDSSLFDQ 349
+ T+RLG +IK HP+F + W L + +E P+ P + D S FDQ
Sbjct: 583 FEREPTKRLGM----TGNIKIHPFFKTINWTLLEKRRLEPPFRPKVK-SPRDYSNFDQ 635
>CE28744 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 879
Score = 219 bits (558), Expect = 5e-57
Identities = 114/296 (38%), Positives = 180/296 (60%), Gaps = 13/296 (4%)
Query: 61 DFQIMRTLGTGSFGRVHLVRSV---HNGRYYAIKVLKKHQIIRM-KQIEHTNDERRMLKL 116
DF+ ++ +G G +G+V VR G YA+KV+ K ++ K + H DER++L+
Sbjct: 22 DFERLKLVGEGGYGKVFQVRKQTGEDKGTIYAMKVITKRKVTGTEKDLRHARDERKILET 81
Query: 117 VEHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLALEYL 176
+ PFL + FQ + L++V++++ GGEL++LL + +P A+FY +E+ LA+E+L
Sbjct: 82 INSPFLCDLHYAFQTNEKLYLVLEFLHGGELYTLLERKSDWPEEYARFYLSEIILAIEHL 141
Query: 177 HSHNIIYRDLKPENILLDRNGHIKITDFGFAKEVI---TVTWTLCGTPDYIAPEVITTKP 233
H H+I+YRDLKP+N++L+ GH+ +TDFG K + T T CGT +Y+APE+I
Sbjct: 142 HGHDIVYRDLKPDNVMLNLAGHVVLTDFGLCKYKLKKGEKTLTFCGTHEYMAPEMIRKVG 201
Query: 234 YNKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFFHPDVVDLLGKLIT 293
++ +VD W+LGIL+++M G PF TP + IL G+V PP DL+ ++I
Sbjct: 202 HDHAVDVWALGILMYDMFMGGPPFTGETPADKDKSILKGKVRLPPKLSASGKDLIKRIIK 261
Query: 294 ADLTRRLGNLQSGPDDIKSHPWFAEVIWEKLVAKDIETPYEPPIAVGVGDSSLFDQ 349
D T R+ DIK H +F E+ W+KL+A D E P++P +A + D S FD+
Sbjct: 262 RDPTLRI-----TIPDIKEHEFFEEIDWDKLMAHDFEPPFKPTLA-NLEDVSHFDE 311
>Hs7019489 [T] KOG0694 Serine/threonine protein kinase
Length = 889
Score = 219 bits (557), Expect = 7e-57
Identities = 117/296 (39%), Positives = 176/296 (58%), Gaps = 8/296 (2%)
Query: 59 LHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRMLKLVE 118
L DF+ + LG G FG+V LV+ G+YYAIK LKK +++ +IE E+R+L+ V
Sbjct: 556 LQDFRCLAVLGRGHFGKVLLVQFKGTGKYYAIKALKKQEVLSRDEIESLYCEKRILEAVG 615
Query: 119 ---HPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLALEY 175
HPFL+ + FQ S + V +++ GG+L + + FP P A+FY A V L L++
Sbjct: 616 CTGHPFLLSLLVCFQTSSHARFVTEFVPGGDLMMQIHEDV-FPEPQARFYVACVVLGLQF 674
Query: 176 LHSHNIIYRDLKPENILLDRNGHIKITDFGFAKEVITV---TWTLCGTPDYIAPEVITTK 232
LH IIYRDLK +N+LLD G +KI DFG KE I T T CGTP+++APEV+T +
Sbjct: 675 LHEKKIIYRDLKLDNLLLDAQGFLKIADFGLCKEGIGFGDRTSTFCGTPEFLAPEVLTQE 734
Query: 233 PYNKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFFHPDVVDLLGKLI 292
Y ++VDWW+LG+L++EML G PF T + ++ I+ + YP F ++ + KL+
Sbjct: 735 AYTQAVDWWALGVLLYEMLVGECPFPGDTEEEVFDCIVNMDAPYPGFLSVQGLEFIQKLL 794
Query: 293 TADLTRRLGNLQSGPDDIKSHPWFAEVIWEKLVAKDIETPYEPPIAVGVGDSSLFD 348
+RLG + ++IK P+F W+ L+A+ I+ P+ P + G D F+
Sbjct: 795 QKCPEKRLGAGEQDAEEIKVQPFFRTTNWQALLARTIQPPFVPTLC-GPADLRYFE 849
>At2g20470 [R] KOG0605 NDR and related serine/threonine kinases
Length = 596
Score = 218 bits (556), Expect = 9e-57
Identities = 121/375 (32%), Positives = 200/375 (53%), Gaps = 55/375 (14%)
Query: 26 DVTVGSQSTDYLLAQQKESLLPQRSTVSKGKYTLHDFQIMRTLGTGSFGRVHLVRSVHNG 85
DV+ Q+ ++KE+ + + + K + DF ++ +G G+FG V + R G
Sbjct: 91 DVSEEDQNNLLKFLEKKET---EYMRLQRHKLGVADFDLLTMIGKGAFGEVRVCREKTTG 147
Query: 86 RYYAIKVLKKHQIIRMKQIEHTNDERRMLKLVEHPFLIRMWGTFQDSRNLFMVMDYIEGG 145
+ YA+K LKK +++R Q+EH ER +L V+ ++++++ +FQD +L++VM+Y+ GG
Sbjct: 148 QVYAMKKLKKAEMLRRGQVEHVRAERNLLAEVDSNYIVKLYCSFQDDDHLYLVMEYLPGG 207
Query: 146 ELFSLLRKSQRFPNPVAKFYAAEVTLALEYLHSHNIIYRDLKPENILLDRNGHIKITDFG 205
++ +LL + AKFY AE LA+E +H HN I+RD+KP+N+LLDR GH++++DFG
Sbjct: 208 DMMTLLMRKDTLTEEEAKFYVAETVLAIESIHRHNYIHRDIKPDNLLLDRYGHLRLSDFG 267
Query: 206 FAKEV------------------------------------------ITVTWTLCGTPDY 223
K + T+ ++ GTPDY
Sbjct: 268 LCKPLDCSAIGENDFSNNSNGSTEQEAGSTAPKRTQQEQLEHWQRNRRTLAYSTVGTPDY 327
Query: 224 IAPEVITTKPYNKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKIL--AGEVVYP--PF 279
IAPEV+ K Y DWWSLG +++EML GY PFY PM T KI+ + +P
Sbjct: 328 IAPEVLLKKGYGMECDWWSLGAIMYEMLVGYPPFYSDDPMSTCRKIVNWKSHLKFPEEAI 387
Query: 280 FHPDVVDLLGKLITADLTRRLGNLQSGPDDIKSHPWFAEVIWEKLVAKDIETPYEPPIAV 339
+ DL+ L+ + RRLG+ G D++K+H WF V W+ + D++ + P +
Sbjct: 388 LSREAKDLINSLL-CSVRRRLGS--KGADELKAHTWFETVDWDTIF--DMDAAFVPEVND 442
Query: 340 GVGDSSLFDQYPEEQ 354
+ D+ F+++ E +
Sbjct: 443 DL-DTQNFEKFDESE 456
>At1g45160 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 1067
Score = 218 bits (556), Expect = 9e-57
Identities = 120/327 (36%), Positives = 183/327 (55%), Gaps = 38/327 (11%)
Query: 54 KGKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRM 113
K + ++ DF+I++ + G+FG+V L R G ++AIKVLKK +IR IE ER +
Sbjct: 662 KDRISIDDFEIIKPISRGAFGKVFLARKRTTGDFFAIKVLKKLDMIRKNDIERILQERNI 721
Query: 114 LKLVEHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLAL 173
L V +PFL+R + +F NL++VM+Y+ GG+L+SLL+K +A+ Y AE+ LAL
Sbjct: 722 LITVRYPFLVRFFYSFTCRDNLYLVMEYLNGGDLYSLLQKVGCLDEEIARIYIAELVLAL 781
Query: 174 EYLHSHNIIYRDLKPENILLDRNGHIKITDFGFAK------------------------- 208
EYLHS I++RDLKP+N+L+ NGHIK+TDFG +K
Sbjct: 782 EYLHSLKIVHRDLKPDNLLIAYNGHIKLTDFGLSKIGLINNTIDLSGHESDVSPRTNSHH 841
Query: 209 -----EVITVTWTLCGTPDYIAPEVITTKPYNKSVDWWSLGILIFEMLAGYTPFYDVTPM 263
E + + GTPDY+APE++ + + DWWS GI++FE+L G PF P
Sbjct: 842 FQKNQEEERIRHSAVGTPDYLAPEILLGTEHGYAADWWSAGIVLFELLTGIPPFTASRPE 901
Query: 264 KTYEKILAGEVVYPPF---FHPDVVDLLGKLITADLTRRLGNLQSGPDDIKSHPWFAEVI 320
K ++ IL G++ +P + DL+ +L+ + +RLG +G ++KSHP+F V
Sbjct: 902 KIFDNILNGKMPWPDVPGEMSYEAQDLINRLLVHEPEKRLG--ANGAAEVKSHPFFQGVD 959
Query: 321 WEKLVAKDIETPYEPPIAVGVGDSSLF 347
WE L + +P + D+S F
Sbjct: 960 WENLALQKAAFVPQPE---SINDTSYF 983
>At1g03920 [R] KOG0605 NDR and related serine/threonine kinases
Length = 569
Score = 218 bits (555), Expect = 1e-56
Identities = 128/397 (32%), Positives = 206/397 (51%), Gaps = 56/397 (14%)
Query: 4 QPVNLQQMXXXXXXXXXXXXXXDVTVGSQSTDYLLAQQKESLLPQRSTVSKGKYTLHDFQ 63
Q NL + DV Q+ ++KE+ + + + K DF+
Sbjct: 82 QMKNLNERKERRTTLEKKLADADVCEEDQTNLMKFLEKKET---EYMRLQRHKMGADDFE 138
Query: 64 IMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRMLKLVEHPFLI 123
++ +G G+FG V +VR ++ G +A+K LKK +++R Q+EH ER +L V+ ++
Sbjct: 139 LLTMIGKGAFGEVRVVREINTGHVFAMKKLKKSEMLRRGQVEHVRAERNLLAEVDSNCIV 198
Query: 124 RMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLALEYLHSHNIIY 183
+++ +FQD+ L+++M+Y+ GG++ +LL + AKFY AE LA+E +H+ N I+
Sbjct: 199 KLYCSFQDNEYLYLIMEYLPGGDMMTLLMRKDTLSEDEAKFYIAESVLAIESIHNRNYIH 258
Query: 184 RDLKPENILLDRNGHIKITDFGFAK-----------------------EVITVT------ 214
RD+KP+N+LLDR GH++++DFG K E ++ T
Sbjct: 259 RDIKPDNLLLDRYGHLRLSDFGLCKPLDCSVIDGEDFTVGNAGSGGGSESVSTTPKRSQQ 318
Query: 215 --------------WTLCGTPDYIAPEVITTKPYNKSVDWWSLGILIFEMLAGYTPFYDV 260
++ GTPDYIAPEV+ K Y DWWSLG +++EML GY PFY
Sbjct: 319 EQLEHWQKNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGAIMYEMLVGYPPFYAD 378
Query: 261 TPMKTYEKIL--AGEVVYP--PFFHPDVVDLLGKLITADLTRRLGNLQSGPDDIKSHPWF 316
PM T KI+ + +P DL+GKL+ + +RLG+ +G IK+HPWF
Sbjct: 379 DPMSTCRKIVNWKTHLKFPEESRLSRGARDLIGKLL-CSVNQRLGS--TGASQIKAHPWF 435
Query: 317 AEVIWEKLVAKDIETPYEPPIAVGVGDSSLFDQYPEE 353
V WEK+ +E + P + + D+ F+++ EE
Sbjct: 436 EGVQWEKIY--QMEAAFIPEVNDDL-DTQNFEKFDEE 469
>At1g30640 [R] KOG0605 NDR and related serine/threonine kinases
Length = 562
Score = 218 bits (554), Expect = 1e-56
Identities = 127/401 (31%), Positives = 207/401 (50%), Gaps = 61/401 (15%)
Query: 4 QPVNLQQMXXXXXXXXXXXXXXDVTVGSQSTDYLLAQQKESLLPQRSTVSKGKYTLHDFQ 63
Q +LQ+ DVTV D L +K+ + R + + K + DF+
Sbjct: 65 QKKSLQERKERRSILEQNLADADVTV-EDKMDILKNFEKKEMEYMR--LQRQKMGVDDFE 121
Query: 64 IMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRMLKLVEHPFLI 123
++ +G G+FG V + + G YA+K LKK +++R Q+EH ER +L V+ PF++
Sbjct: 122 LLSIIGRGAFGEVRICKEKSTGSVYAMKKLKKSEMLRRGQVEHVKAERNVLAEVDSPFIV 181
Query: 124 RMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLALEYLHSHNIIY 183
++ +FQD +L+++M+Y+ GG++ +LL + +FY A+ LA+E +H HN ++
Sbjct: 182 KLCYSFQDDEHLYLIMEYLPGGDMMTLLMRKDTLREDETRFYVAQTILAIESIHKHNYVH 241
Query: 184 RDLKPENILLDRNGHIKITDFGFAKEV--------------------------------- 210
RD+KP+N+L+ RNGHIK++DFG +K +
Sbjct: 242 RDIKPDNLLITRNGHIKLSDFGLSKSLESKNFPDFKAELVDRSTKPAAEHDRLSKPPSAP 301
Query: 211 ---------------ITVTWTLCGTPDYIAPEVITTKPYNKSVDWWSLGILIFEMLAGYT 255
T+ ++ GTPDYIAPEV+ K Y DWWSLG ++FEML G+
Sbjct: 302 RRTQQEQLLHWQQNRRTLAFSTVGTPDYIAPEVLLKKGYGMECDWWSLGAIMFEMLVGFP 361
Query: 256 PFYDVTPMKTYEKILAGE--VVYP--PFFHPDVVDLLGKLITADLTRRLGNLQSGPDDIK 311
PFY P+ T KI+ + + +P +V DL+ +L+ ++ +RLG G +IK
Sbjct: 362 PFYSEEPLATCRKIVNWKTCLKFPDEAKLSIEVKDLIRRLL-CNVEQRLGT--KGVHEIK 418
Query: 312 SHPWFAEVIWEKLVAKDIETPYEPPIAVGVGDSSLFDQYPE 352
+HPWF V WE+L + PY P + + D+ F+++ E
Sbjct: 419 AHPWFRGVEWERLY--ESNAPYIPQVKHEL-DTQNFEKFDE 456
>7297611 [T] KOG0614 cGMP-dependent protein kinase
Length = 1003
Score = 217 bits (552), Expect = 3e-56
Identities = 110/284 (38%), Positives = 184/284 (64%), Gaps = 7/284 (2%)
Query: 59 LHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERR-MLKLV 117
+ + + + TLG G+FGRV LV +N + A+K++KK ++++ QIEH +E+ M+K
Sbjct: 691 ISELKKIATLGCGAFGRVDLV--AYNQQALALKIIKKIEVVKQDQIEHVYNEKNVMIKCR 748
Query: 118 EHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLALEYLH 177
+ PF+++++ T+++ + ++ +M+ GG++++++ K Q F AKF A V A +YLH
Sbjct: 749 QSPFIVQLYRTYRNDKYVYFLMEACMGGDVWTVMSKRQYFDEKTAKFIAGCVVEAFDYLH 808
Query: 178 SHNIIYRDLKPENILLDRNGHIKITDFGFAKEV--ITVTWTLCGTPDYIAPEVITTKPYN 235
SH+ IYRDLKPEN++L +G+ K+ DFGFAK V T T GTP+Y+APE+I + ++
Sbjct: 809 SHHFIYRDLKPENLMLGTDGYCKLVDFGFAKFVRQNEKTNTFAGTPEYVAPEIILDRGHD 868
Query: 236 KSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAG-EVVYPPFFHPDVVDLLGKLITA 294
++VD+W+LGIL++E+L G TPF V +K Y++IL+G +V++ P P L + +
Sbjct: 869 RAVDYWALGILVYELLVGKTPFRGVNQIKIYQQILSGIDVIHMPSRIPKSAQHLVRHLCK 928
Query: 295 DL-TRRLGNLQSGPDDIKSHPWFAEVIWEKLVAKDIETPYEPPI 337
L RLG + G DIK H WF + W++L K + +P + P+
Sbjct: 929 QLPAERLGYQRKGIADIKRHSWFESLDWQRLKLKQLPSPIKRPL 972
>CE17354 [T] KOG0694 Serine/threonine protein kinase
Length = 567
Score = 216 bits (550), Expect = 4e-56
Identities = 113/304 (37%), Positives = 177/304 (58%), Gaps = 5/304 (1%)
Query: 56 KYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRMLK 115
K+ L F +++ LG GSFG+V LV +YA+K LKK I+ E T ERR+L
Sbjct: 232 KFALPHFNLLKVLGKGSFGKVMLVELKGKNEFYAMKCLKKDVILEDDDTECTYIERRVLI 291
Query: 116 LVEH-PFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLALE 174
L PFL +++ +FQ + LF VM+Y+ GG+L +++ ++F +FYA E+ +AL+
Sbjct: 292 LASQCPFLCQLFCSFQTNEYLFFVMEYLNGGDLMHHIQQIKKFDEARTRFYACEIVVALQ 351
Query: 175 YLHSHNIIYRDLKPENILLDRNGHIKITDFGFAKEVIT----VTWTLCGTPDYIAPEVIT 230
+LH++NIIYRDLK +N+LLD +GHIK+ DFG AK + + T CGTPDYI+PE+I
Sbjct: 352 FLHTNNIIYRDLKLDNVLLDCDGHIKLADFGMAKTEMNRENGMASTFCGTPDYISPEIIK 411
Query: 231 TKPYNKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFFHPDVVDLLGK 290
+ YN++VD+WS G+L++EML G +PF+ + ++ IL +P + L
Sbjct: 412 GQLYNEAVDFWSFGVLMYEMLVGQSPFHGEGEDELFDSILNERPYFPKTISKEAAKCLSA 471
Query: 291 LITADLTRRLGNLQSGPDDIKSHPWFAEVIWEKLVAKDIETPYEPPIAVGVGDSSLFDQY 350
L + RLG + I+ H +F V W++ + + P++P I S+ D +
Sbjct: 472 LFDRNPNTRLGMPECPDGPIRQHCFFRGVDWKRFENRQVPPPFKPNIKSNSDASNFDDDF 531
Query: 351 PEEQ 354
E+
Sbjct: 532 TNEK 535
>CE17353 [T] KOG0694 Serine/threonine protein kinase
Length = 704
Score = 216 bits (550), Expect = 4e-56
Identities = 113/304 (37%), Positives = 177/304 (58%), Gaps = 5/304 (1%)
Query: 56 KYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRMLK 115
K+ L F +++ LG GSFG+V LV +YA+K LKK I+ E T ERR+L
Sbjct: 369 KFALPHFNLLKVLGKGSFGKVMLVELKGKNEFYAMKCLKKDVILEDDDTECTYIERRVLI 428
Query: 116 LVEH-PFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLALE 174
L PFL +++ +FQ + LF VM+Y+ GG+L +++ ++F +FYA E+ +AL+
Sbjct: 429 LASQCPFLCQLFCSFQTNEYLFFVMEYLNGGDLMHHIQQIKKFDEARTRFYACEIVVALQ 488
Query: 175 YLHSHNIIYRDLKPENILLDRNGHIKITDFGFAKEVIT----VTWTLCGTPDYIAPEVIT 230
+LH++NIIYRDLK +N+LLD +GHIK+ DFG AK + + T CGTPDYI+PE+I
Sbjct: 489 FLHTNNIIYRDLKLDNVLLDCDGHIKLADFGMAKTEMNRENGMASTFCGTPDYISPEIIK 548
Query: 231 TKPYNKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFFHPDVVDLLGK 290
+ YN++VD+WS G+L++EML G +PF+ + ++ IL +P + L
Sbjct: 549 GQLYNEAVDFWSFGVLMYEMLVGQSPFHGEGEDELFDSILNERPYFPKTISKEAAKCLSA 608
Query: 291 LITADLTRRLGNLQSGPDDIKSHPWFAEVIWEKLVAKDIETPYEPPIAVGVGDSSLFDQY 350
L + RLG + I+ H +F V W++ + + P++P I S+ D +
Sbjct: 609 LFDRNPNTRLGMPECPDGPIRQHCFFRGVDWKRFENRQVPPPFKPNIKSNSDASNFDDDF 668
Query: 351 PEEQ 354
E+
Sbjct: 669 TNEK 672
>7294770 [T] KOG0603 Ribosomal protein S6 kinase
Length = 1207
Score = 215 bits (548), Expect = 7e-56
Identities = 125/316 (39%), Positives = 187/316 (58%), Gaps = 21/316 (6%)
Query: 58 TLHDFQIMRTLGTGSFGRVHLVRSVHN---GRYYAIKVLKKHQII-RMKQIEHTNDERRM 113
+L+DF+I+R LGTG++GRV LVR + G+ YA+KVL K ++ + K EHT ER +
Sbjct: 257 SLNDFKIIRVLGTGAYGRVFLVRKLTRHDAGKLYAMKVLNKITVVQKRKTAEHTKTERVV 316
Query: 114 LKLVE-HPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLA 172
L+ ++ +PFL+ + FQ S L++V+D+ GGELF+ L S+ F + Y AEV LA
Sbjct: 317 LEAIQRNPFLVSLHYAFQSSSKLYLVLDFANGGELFTHLYHSENFEESRVRVYIAEVVLA 376
Query: 173 LEYLHSHNIIYRDLKPENILLDRNGHIKITDFGFAKEVITV-----TWTLCGTPDYIAPE 227
LE LH IIYRD+K ENILLD GHI ++DFG +K ++T + CGT +Y+APE
Sbjct: 377 LEQLHQLGIIYRDIKLENILLDGEGHIVLSDFGLSK-ILTAENEYRAHSFCGTLEYMAPE 435
Query: 228 VITTKP--YNKSVDWWSLGILIFEMLAGYTPFY----DVTPMKTYEKILAGEVVYPPFFH 281
+I T P ++ +VDWWS+G+L FE+L G +PF V + +I + + P F
Sbjct: 436 IIRTGPPGHDSAVDWWSVGVLTFELLTGASPFATSDGQVQQSEISRRIQKEQPMIPSSFS 495
Query: 282 PDVVDLLGKLITADLTRRLGNLQSGPDDIKSHPWFAEVIWEKLVAKDIETPYEPPIA--- 338
+ D + K++ + RRLG +IK HP+F + W++L K + PY+P +
Sbjct: 496 ANARDFVLKMLEKNPKRRLGGNHRDASEIKEHPFFNGINWQELRTKRRKAPYKPTLTAED 555
Query: 339 -VGVGDSSLFDQYPEE 353
V + DQ PE+
Sbjct: 556 DVQNFSNEFTDQVPED 571
Score = 66.6 bits (161), Expect = 6e-11
Identities = 50/209 (23%), Positives = 95/209 (44%), Gaps = 23/209 (11%)
Query: 61 DFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRMLKLVEHP 120
D ++ G++G H V + K++ + + + E L H
Sbjct: 622 DLELGTRTSNGAYGTCHFVVDSSTDLVFLAKIIP---LSKFRPSEVDALISCALDTTNHK 678
Query: 121 FLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLALEYLHSHN 180
++ GTF++ ++VM+Y+ G EL + +R + + ++ +A+ ++HS +
Sbjct: 679 NIVSYHGTFREKCETWIVMEYLSGPELTASIRMDEDSCREIF----LQLVMAVRHIHSKH 734
Query: 181 IIYRDLKPENILLD--RNGHIKITDFG-------FAKEVITVTWTLCGTPDYIAPEVITT 231
I+ DLKPENI+ + + +K+ DFG F +TL DY PE++
Sbjct: 735 FIHGDLKPENIMFENREDRTVKLIDFGSACYNNRFKSWKDKPRYTL----DYAPPEMLAD 790
Query: 232 K---PYNKSVDWWSLGILIFEMLAGYTPF 257
Y+ +VD + LG ++ ML G+ P+
Sbjct: 791 ANLVTYSPAVDIYGLGATLYTMLVGHRPY 819
>At5g62310 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 1168
Score = 214 bits (545), Expect = 2e-55
Identities = 115/309 (37%), Positives = 180/309 (58%), Gaps = 39/309 (12%)
Query: 53 SKGKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERR 112
+K + ++ DF+I++ + G+FGRV L + G +AIKVLKK +IR +E ER
Sbjct: 745 AKDRTSIEDFEIIKPISRGAFGRVFLAKKRATGDLFAIKVLKKADMIRKNAVESILAERN 804
Query: 113 MLKLVEHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLA 172
+L V +PF++R + +F NL++VM+Y+ GG+LFSLLR +A+ Y AEV LA
Sbjct: 805 ILISVRNPFVVRFFYSFTCRENLYLVMEYLNGGDLFSLLRNLGCLDEDMARIYIAEVVLA 864
Query: 173 LEYLHSHNIIYRDLKPENILLDRNGHIKITDFGFAK-EVITVT----------------- 214
LEYLHS NII+RDLKP+N+L++++GHIK+TDFG +K +I T
Sbjct: 865 LEYLHSVNIIHRDLKPDNLLINQDGHIKLTDFGLSKVGLINSTDDLSGESSLGNSGFFAE 924
Query: 215 ----------------WTLCGTPDYIAPEVITTKPYNKSVDWWSLGILIFEMLAGYTPFY 258
+ GTPDY+APE++ + K+ DWWS+G+++FE+L G PF
Sbjct: 925 DGSKAQHSQGKDSRKKHAVVGTPDYLAPEILLGMGHGKTADWWSVGVILFEVLVGIPPFN 984
Query: 259 DVTPMKTYEKILAGEVVYPPF---FHPDVVDLLGKLITADLTRRLGNLQSGPDDIKSHPW 315
TP + +E I+ ++ +P + DL+ KL+T + +RLG +G ++K H +
Sbjct: 985 AETPQQIFENIINRDIPWPNVPEEISYEAHDLINKLLTENPVQRLG--ATGAGEVKQHHF 1042
Query: 316 FAEVIWEKL 324
F ++ W+ L
Sbjct: 1043 FKDINWDTL 1051
>CE19898 [T] KOG0614 cGMP-dependent protein kinase
Length = 737
Score = 214 bits (544), Expect = 2e-55
Identities = 117/302 (38%), Positives = 179/302 (58%), Gaps = 7/302 (2%)
Query: 58 TLHDFQIMRTLGTGSFGRVHLVR-SVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRMLKL 116
TL + + + TLG G FGRV LV + + +A+K LKK I+ +Q EH ER ++
Sbjct: 422 TLKNVKRLATLGVGGFGRVELVCVNGDKAKTFALKALKKKHIVDTRQQEHIFAERNIMME 481
Query: 117 VEHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLALEYL 176
++++++ TF+D + ++M+++ GGEL++ LR F + A+FY A V LEYL
Sbjct: 482 TSTDWIVKLYKTFRDQKFVYMLLEVCLGGELWTTLRDRGHFDDYTARFYVACVLEGLEYL 541
Query: 177 HSHNIIYRDLKPENILLDRNGHIKITDFGFAKEVIT--VTWTLCGTPDYIAPEVITTKPY 234
H NI+YRDLKPEN LL G++K+ DFGFAK++ + TWT CGTP+Y++PE+I K +
Sbjct: 542 HRKNIVYRDLKPENCLLANTGYLKLVDFGFAKKLASGRKTWTFCGTPEYVSPEIILNKGH 601
Query: 235 NKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAG-EVVYPP--FFHPDVVDLLGKL 291
+++ D+W+LGI I E++ G PF PMKTY IL G + + P L+ KL
Sbjct: 602 DQAADYWALGIYICELMLGRPPFQASDPMKTYTLILKGVDALEIPNRRIGKTATALVKKL 661
Query: 292 ITADLTRRLGNLQSGPDDIKSHPWFAEVIWEKLVAKDIETPYEPPIAVGVGDSSLFDQYP 351
+ RLG+ G +DI+ H WF WE L ++ ++ P P ++ D + FD YP
Sbjct: 662 CRDNPGERLGSGSGGVNDIRKHRWFMGFDWEGLRSRTLKPPILPKVS-NPADVTNFDNYP 720
Query: 352 EE 353
+
Sbjct: 721 PD 722
>CE19897 [T] KOG0614 cGMP-dependent protein kinase
Length = 780
Score = 214 bits (544), Expect = 2e-55
Identities = 117/302 (38%), Positives = 179/302 (58%), Gaps = 7/302 (2%)
Query: 58 TLHDFQIMRTLGTGSFGRVHLVR-SVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRMLKL 116
TL + + + TLG G FGRV LV + + +A+K LKK I+ +Q EH ER ++
Sbjct: 465 TLKNVKRLATLGVGGFGRVELVCVNGDKAKTFALKALKKKHIVDTRQQEHIFAERNIMME 524
Query: 117 VEHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLALEYL 176
++++++ TF+D + ++M+++ GGEL++ LR F + A+FY A V LEYL
Sbjct: 525 TSTDWIVKLYKTFRDQKFVYMLLEVCLGGELWTTLRDRGHFDDYTARFYVACVLEGLEYL 584
Query: 177 HSHNIIYRDLKPENILLDRNGHIKITDFGFAKEVIT--VTWTLCGTPDYIAPEVITTKPY 234
H NI+YRDLKPEN LL G++K+ DFGFAK++ + TWT CGTP+Y++PE+I K +
Sbjct: 585 HRKNIVYRDLKPENCLLANTGYLKLVDFGFAKKLASGRKTWTFCGTPEYVSPEIILNKGH 644
Query: 235 NKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAG-EVVYPP--FFHPDVVDLLGKL 291
+++ D+W+LGI I E++ G PF PMKTY IL G + + P L+ KL
Sbjct: 645 DQAADYWALGIYICELMLGRPPFQASDPMKTYTLILKGVDALEIPNRRIGKTATALVKKL 704
Query: 292 ITADLTRRLGNLQSGPDDIKSHPWFAEVIWEKLVAKDIETPYEPPIAVGVGDSSLFDQYP 351
+ RLG+ G +DI+ H WF WE L ++ ++ P P ++ D + FD YP
Sbjct: 705 CRDNPGERLGSGSGGVNDIRKHRWFMGFDWEGLRSRTLKPPILPKVS-NPADVTNFDNYP 763
Query: 352 EE 353
+
Sbjct: 764 PD 765
>Hs18579683 [R] KOG0605 NDR and related serine/threonine kinases
Length = 464
Score = 213 bits (542), Expect = 4e-55
Identities = 114/339 (33%), Positives = 182/339 (53%), Gaps = 48/339 (14%)
Query: 59 LHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRMLKLVE 118
L DF+ ++ +G G+FG V LV+ G YA+K+L+K ++ +Q+ H ER +L +
Sbjct: 87 LDDFESLKVIGRGAFGEVRLVQKKDTGHIYAMKILRKSDMLEKEQVAHIRAERDILVEAD 146
Query: 119 HPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLALEYLHS 178
++++M+ +FQD RNL+++M+++ GG++ +LL K +FY +E LA++ +H
Sbjct: 147 GAWVVKMFYSFQDKRNLYLIMEFLPGGDMMTLLMKKDTLTEEETQFYISETVLAIDAIHQ 206
Query: 179 HNIIYRDLKPENILLDRNGHIKITDFG--------------------------------- 205
I+RD+KP+N+LLD GH+K++DFG
Sbjct: 207 LGFIHRDIKPDNLLLDAKGHVKLSDFGLCTGLKKAHRTEFYRNLTHNPPSDFSFQNMNSK 266
Query: 206 -----FAKEVITVTWTLCGTPDYIAPEVITTKPYNKSVDWWSLGILIFEMLAGYTPFYDV 260
+ K + ++ GTPDYIAPEV YNK DWWSLG++++EML GY PF
Sbjct: 267 RKAETWKKNRRQLAYSTVGTPDYIAPEVFMQTGYNKLCDWWSLGVIMYEMLIGYPPFCSE 326
Query: 261 TPMKTYEKILAGE--VVYPPF--FHPDVVDLLGKLITADLTRRLGNLQSGPDDIKSHPWF 316
TP +TY K++ + +V+PP DL+ + D R+GN SG ++IK HP+F
Sbjct: 327 TPQETYRKVMNWKETLVFPPEVPISEKAKDLILR-FCIDSENRIGN--SGVEEIKGHPFF 383
Query: 317 AEVIWEKLVAKDIETPYEPPIAVGVGDSSLFDQYPEEQL 355
V WE + + P E + D+S FD +PE +
Sbjct: 384 EGVDWEHIRERPAAIPIE---IKSIDDTSNFDDFPESDI 419
>CE18699 [T] KOG0694 Serine/threonine protein kinase
Length = 1018
Score = 212 bits (540), Expect = 6e-55
Identities = 110/288 (38%), Positives = 172/288 (59%), Gaps = 9/288 (3%)
Query: 58 TLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRMLKL- 116
T+ F+++ LG G FG+V L + YYA+KVLKK I+ ++E E+R+ ++
Sbjct: 686 TVEQFRLISVLGRGHFGKVILSQHNPTSNYYALKVLKKGDILGRDEVESLMVEKRIFEVS 745
Query: 117 --VEHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLALE 174
HPFL+ + G FQ + ++F M+Y GG+L + F FYAA V L L+
Sbjct: 746 SRARHPFLVNLNGCFQTNEHVFFCMEYSMGGDLMRHIHDDV-FDEVRGCFYAACVVLGLD 804
Query: 175 YLHSHNIIYRDLKPENILLDRNGHIKITDFGFAKEVI---TVTWTLCGTPDYIAPEVITT 231
+LH HNIIYRD+K +N+LLDR G++KI DFG KE + T T CGTP+++APEV++
Sbjct: 805 FLHKHNIIYRDIKLDNLLLDREGYVKIADFGLCKENMGPFDKTSTFCGTPEFLAPEVLSD 864
Query: 232 KPYNKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFFHPDVVDLLGKL 291
Y +++DWW LG+LIFEML G PF + ++ I++ +V YP + + + ++ +L
Sbjct: 865 SSYTRAIDWWGLGVLIFEMLVGEPPFSGDDEEEIFDSIISEDVRYPRYLSVESIAIMRRL 924
Query: 292 ITADLTRRLGNLQSGPDDIKSHPWFAEVIWE--KLVAKDIETPYEPPI 337
+ +RLG + +DIK +F + WE KL+ ++I P++P I
Sbjct: 925 LRKVPEKRLGYGERDAEDIKIQRFFRHISWEWDKLLNREIRPPFQPQI 972
>YBL105c [T] KOG0694 Serine/threonine protein kinase
Length = 1151
Score = 212 bits (539), Expect = 8e-55
Identities = 119/328 (36%), Positives = 190/328 (57%), Gaps = 11/328 (3%)
Query: 31 SQSTDYLLAQQKE---SLLPQRSTVSKGKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRY 87
S++TD Q+ + S ++ + K +L +F +++ LG G+FG+V L +S + R
Sbjct: 790 SRTTDQQSPQKSQTSTSAKHKKRAAKRRKVSLDNFVLLKVLGKGNFGKVILSKSKNTDRL 849
Query: 88 YAIKVLKKHQIIRMKQIEHTNDERRMLKLV---EHPFLIRMWGTFQDSRNLFMVMDYIEG 144
AIKVLKK II+ IE E+++ L +HPFL ++ +FQ ++ M++I G
Sbjct: 850 CAIKVLKKDNIIQNHDIESARAEKKVFLLATKTKHPFLTNLYCSFQTENRIYFAMEFIGG 909
Query: 145 GELFSLLRKSQRFPNPVAKFYAAEVTLALEYLHSHNIIYRDLKPENILLDRNGHIKITDF 204
G+L ++ +QR AKFYAAEV LAL+Y H + +IYRDLK ENILL GHIKI D+
Sbjct: 910 GDLMWHVQ-NQRLSVRRAKFYAAEVLLALKYFHDNGVIYRDLKLENILLTPEGHIKIADY 968
Query: 205 GFAKEVITV---TWTLCGTPDYIAPEVITTKPYNKSVDWWSLGILIFEMLAGYTPFYDVT 261
G K+ + T T CGTP+++APE++ + Y K+VDWW+ G+L+++ML +PF
Sbjct: 969 GLCKDEMWYGNRTSTFCGTPEFMAPEILKEQEYTKAVDWWAFGVLLYQMLLCQSPFSGDD 1028
Query: 262 PMKTYEKILAGEVVYPPFFHPDVVDLLGKLITADLTRRLGNLQSGPDDIKSHPWFAEVIW 321
+ + IL E +YP ++V + L+T D +RLG D++ P+F + +
Sbjct: 1029 EDEVFNAILTDEPLYPIDMAGEIVQIFQGLLTKDPEKRLGAGPRDADEVMEEPFFRNINF 1088
Query: 322 EKLVAKDIETPYEPPIAVGVGDSSLFDQ 349
+ ++ ++ PY P I D+S F+Q
Sbjct: 1089 DDILNLRVKPPYIPEIK-SPEDTSYFEQ 1115
>7303111 [T] KOG0695 Serine/threonine protein kinase
Length = 690
Score = 212 bits (539), Expect = 8e-55
Identities = 113/294 (38%), Positives = 172/294 (58%), Gaps = 14/294 (4%)
Query: 56 KYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRMLK 115
+Y+L+DF+++R +G GS+ +V +V R YA+KV+KK + + I+ E+ + +
Sbjct: 255 QYSLNDFELIRVIGRGSYAKVLMVELRRTRRIYAMKVIKKALVTDDEDIDWVQTEKHVFE 314
Query: 116 LVE-HPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLALE 174
HPFL+ + FQ LF V++++ GG+L +++ +R P A+FYAAE++LAL
Sbjct: 315 TASNHPFLVGLHSCFQTPSRLFFVIEFVRGGDLMYHMQRQRRLPEEHARFYAAEISLALN 374
Query: 175 YLHSHNIIYRDLKPENILLDRNGHIKITDFGFAKEVI---TVTWTLCGTPDYIAPEVITT 231
+LH IIYRDLK +N+LLD GHIK+TD+G KE I T T CGTP+YIAPE++
Sbjct: 375 FLHEKGIIYRDLKLDNVLLDHEGHIKLTDYGMCKEGIRPGDTTSTFCGTPNYIAPEILRG 434
Query: 232 KPYNKSVDWWSLGILIFEMLAGYTPF---------YDVTPMKTYEKILAGEVVYPPFFHP 282
+ Y SVDWW+LG+L++EMLAG +PF T ++ IL + P
Sbjct: 435 EDYGFSVDWWALGVLLYEMLAGRSPFDLAGASENPDQNTEDYLFQVILEKTIRIPRSLSV 494
Query: 283 DVVDLLGKLITADLTRRLG-NLQSGPDDIKSHPWFAEVIWEKLVAKDIETPYEP 335
+L + + RLG + +S DI SHP+F + WE L K + P++P
Sbjct: 495 RAASVLKGFLNKNPADRLGCHRESAFMDIVSHPFFKNMDWELLERKQVTPPFKP 548
>Hs14149671 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 1734
Score = 211 bits (538), Expect = 1e-54
Identities = 118/328 (35%), Positives = 184/328 (55%), Gaps = 31/328 (9%)
Query: 46 LPQRSTVSKGKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIE 105
LP + T S+ DF+ ++ + G++G V LVR + +A+K + K +I QI+
Sbjct: 501 LPSKKTPSE-----EDFETIKLISNGAYGAVFLVRHKSTRQRFAMKKINKQNLILRNQIQ 555
Query: 106 HTNDERRMLKLVEHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFY 165
ER +L E+PF++ M+ +F R+L MVM+Y+EGG+ +LL+ P + + Y
Sbjct: 556 QAFVERDILTFAENPFVVSMFCSFDTKRHLCMVMEYVEGGDCATLLKNIGALPVDMVRLY 615
Query: 166 AAEVTLALEYLHSHNIIYRDLKPENILLDRNGHIKITDFGFAK-EVITVTWTL------- 217
AE LALEYLH++ I++RDLKP+N+L+ GHIK+TDFG +K ++++T L
Sbjct: 616 FAETVLALEYLHNYGIVHRDLKPDNLLITSMGHIKLTDFGLSKMGLMSLTTNLYEGHIEK 675
Query: 218 ----------CGTPDYIAPEVITTKPYNKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYE 267
CGTP+YIAPEVI + Y K VDWW++GI+++E L G PF+ TP + +
Sbjct: 676 DAREFLDKQVCGTPEYIAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFG 735
Query: 268 KILAGEVVYP---PFFHPDVVDLLGKLITADLTRRLGNLQSGPDDIKSHPWFAEVIWEKL 324
++++ E+V+P PD DL KL+ + RLG ++K HP+F + W L
Sbjct: 736 QVISDEIVWPEGDEALPPDAQDLTSKLLHQNPLERLGT--GSAYEVKQHPFFTGLDWTGL 793
Query: 325 VAKDIETPYEPPIAVGVGDSSLFDQYPE 352
+ + E P D+S FD E
Sbjct: 794 LRQKAEF---IPQLESEDDTSYFDTRSE 818
>At5g09890 [R] KOG0605 NDR and related serine/threonine kinases
Length = 495
Score = 211 bits (536), Expect = 2e-54
Identities = 118/352 (33%), Positives = 189/352 (53%), Gaps = 57/352 (16%)
Query: 52 VSKGKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDER 111
+ + K + DF+++ +G G+FG V L R YA+K LKK +++ Q+EH ER
Sbjct: 92 LQRRKIGIDDFELLTVIGKGAFGEVRLCRLRSTSEVYAMKKLKKTEMLSRGQVEHVRSER 151
Query: 112 RMLKLVEHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTL 171
+L V+ ++++++ +FQDS L+++M+Y+ GG++ +LL + VA+FY AE L
Sbjct: 152 NLLAEVDSRYIVKLFYSFQDSECLYLIMEYLPGGDIMTLLMREDILSEDVARFYIAESIL 211
Query: 172 ALEYLHSHNIIYRDLKPENILLDRNGHIKITDFGFAK--------------EVIT----- 212
A+ +H HN ++RD+KP+N++LD++GH+K++DFG K E+++
Sbjct: 212 AIHSIHQHNYVHRDIKPDNLILDKSGHLKLSDFGLCKPLDDKYSSLLLEDDEMLSQDSEN 271
Query: 213 ----------------------------VTWTLCGTPDYIAPEVITTKPYNKSVDWWSLG 244
+ ++ GT DY+APEV+ K Y DWWSLG
Sbjct: 272 QSGKSDADKAPWQMPKEQLLQWKRNRRALAYSTVGTLDYMAPEVLLKKGYGMECDWWSLG 331
Query: 245 ILIFEMLAGYTPFYDVTPMKTYEKILAGEVV--YP--PFFHPDVVDLLGKLITADLTRRL 300
+++EML GY PF P T KI+ V +P P + DL+ +L+ D+ RL
Sbjct: 332 AILYEMLVGYPPFCSDDPRITCRKIINWRVCLKFPEEPKISDEARDLICRLL-CDVDSRL 390
Query: 301 GNLQSGPDDIKSHPWFAEVIWEKLVAKDIETPYEPPIAVGVGDSSLFDQYPE 352
G G ++IKSHPWF W+KL D+E Y PI G D+ F+++PE
Sbjct: 391 GT--RGVEEIKSHPWFKGTPWDKLY--DMEAAYR-PIVDGELDTQNFEKFPE 437
>CE28760 [R] KOG0605 NDR and related serine/threonine kinases
Length = 467
Score = 210 bits (534), Expect = 3e-54
Identities = 120/371 (32%), Positives = 191/371 (51%), Gaps = 64/371 (17%)
Query: 31 SQSTDYLLAQQKESLLPQRSTVSKGKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAI 90
S+ TDYL + + + T++DF+ ++ +G G+FG V LV+ G YA+
Sbjct: 62 SKETDYL-------------RLKRTRLTVNDFESLKVIGRGAFGEVRLVQKHDTGHIYAM 108
Query: 91 KVLKKHQIIRMKQIEHTNDERRMLKLVEHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSL 150
K+L+K +++ +Q H ER +L + ++++M+ +FQD NL++VM+++ GG++ +L
Sbjct: 109 KILRKSEMVEKEQTAHVRAERDILSEADCDWVVKMYYSFQDYSNLYLVMEFLPGGDMMTL 168
Query: 151 LRKSQRFPNPVAKFYAAEVTLALEYLHSHNIIYRDLKPENILLDRNGHIKITDFG----- 205
L K +FY AE LA++++HS I+RD+KP+N+LLD GH+K++DFG
Sbjct: 169 LIKKDTLTEEATQFYIAEAALAIQFIHSLGFIHRDIKPDNLLLDARGHVKLSDFGLCTGL 228
Query: 206 ------------------------FAKEVITVTW---------TLCGTPDYIAPEVITTK 232
F + TW + GTPDYIAPEV
Sbjct: 229 KKFHRTDHYRNWPSTLPPDFISKPFESKRKAETWKRNRRAYAYSTVGTPDYIAPEVFQPN 288
Query: 233 PYNKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGE--VVYPPFFHPDV-VDLLG 289
Y KS DWWSLG++++EML GY PF P +TY K++ + +V+P +
Sbjct: 289 GYTKSCDWWSLGVIMYEMLIGYPPFCSELPQETYRKVINWQQTLVFPSDVPISIEAKATI 348
Query: 290 KLITADLTRRLGNLQSGPDDIKSHPWFAEVIWEKLVAKDIETPYEPPIAV---GVGDSSL 346
K + RRLGN G D+IK P+ + W + + PPI V + D+S
Sbjct: 349 KRFCCEAERRLGN-HGGLDEIKQCPFVKRIDWNHIRER------PPPIRVTVKSIDDTSN 401
Query: 347 FDQYPEEQLDY 357
FD +P+E L +
Sbjct: 402 FDDFPDEDLTW 412
>Hs17455844 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 1139
Score = 209 bits (532), Expect = 5e-54
Identities = 115/332 (34%), Positives = 184/332 (54%), Gaps = 26/332 (7%)
Query: 53 SKGKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERR 112
S+ K DF+ ++ + G++G V+LVR + +AIK + K +I QI+ ER
Sbjct: 188 SRRKPCESDFETIKLISNGAYGAVYLVRHRDTRQRFAIKKINKQNLILRNQIQQVFVERD 247
Query: 113 MLKLVEHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLA 172
+L E+PF++ M+ +F+ R+L MVM+Y+EGG+ +LL+ P +A+ Y AE LA
Sbjct: 248 ILTFAENPFVVSMFCSFETRRHLCMVMEYVEGGDCATLLKNMGPLPVDMARLYFAETVLA 307
Query: 173 LEYLHSHNIIYRDLKPENILLDRNGHIKITDFGFAKEVITVTWT---------------- 216
LEYLH++ I++RDLKP+N+L+ GHIK+TDFG +K + T
Sbjct: 308 LEYLHNYGIVHRDLKPDNLLITSLGHIKLTDFGLSKIGLMSMATNLYEGHIEKDAREFID 367
Query: 217 --LCGTPDYIAPEVITTKPYNKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEV 274
+CGTP+YIAPEVI + Y K VDWW++G++++E L G PF+ TP + + ++++ E+
Sbjct: 368 KQVCGTPEYIAPEVIFRQGYGKPVDWWAMGVVLYEFLVGCVPFFGDTPEELFGQVVSDEI 427
Query: 275 VYP---PFFHPDVVDLLGKLITADLTRRLGNLQSGPDDIKSHPWFAEVIWEKLVAKDIET 331
++P D DL+ +L+ RLG G ++K HP+F + W L+ E
Sbjct: 428 MWPEGDEALPADAQDLITRLLRQSPLDRLGT--GGTHEVKQHPFFLALDWAGLLRHKAEF 485
Query: 332 PYEPPIAVGVGDSSLFDQYPEEQLDYGVQGED 363
P D+S FD E G + ++
Sbjct: 486 ---VPQLEAEDDTSYFDTRSERYRHLGSEDDE 514
>Hs4505695 [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 556
Score = 209 bits (531), Expect = 7e-54
Identities = 109/270 (40%), Positives = 159/270 (58%), Gaps = 6/270 (2%)
Query: 61 DFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRMLKLVEHP 120
DF+ + LG GSF V L R + R YAIK+L+K II+ ++ + ER ++ ++HP
Sbjct: 81 DFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDHP 140
Query: 121 FLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLALEYLHSHN 180
F ++++ TFQD L+ + Y + GEL +RK F +FY AE+ ALEYLH
Sbjct: 141 FFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHGKG 200
Query: 181 IIYRDLKPENILLDRNGHIKITDFGFAKEVITVTW-----TLCGTPDYIAPEVITTKPYN 235
II+RDLKPENILL+ + HI+ITDFG AK + + + GT Y++PE++T K
Sbjct: 201 IIHRDLKPENILLNEDMHIQITDFGTAKVLSPESKQARANSFVGTAQYVSPELLTEKSAC 260
Query: 236 KSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFFHPDVVDLLGKLITAD 295
KS D W+LG +I++++AG PF ++KI+ E +P F P DL+ KL+ D
Sbjct: 261 KSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYDFPEKFFPKARDLVEKLLVLD 320
Query: 296 LTRRLG-NLQSGPDDIKSHPWFAEVIWEKL 324
T+RLG G +K+HP+F V WE L
Sbjct: 321 ATKRLGCEEMEGYGPLKAHPFFESVTWENL 350
>At3g23310 [R] KOG0605 NDR and related serine/threonine kinases
Length = 568
Score = 208 bits (530), Expect = 9e-54
Identities = 109/314 (34%), Positives = 170/314 (53%), Gaps = 53/314 (16%)
Query: 61 DFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRMLKLVEHP 120
DF+ + +G G+FG V + R G YA+K LKK +++R Q+EH ER +L V+
Sbjct: 119 DFEPLTMIGKGAFGEVRICREKTTGNVYAMKKLKKSEMLRRGQVEHVKAERNLLAEVDSN 178
Query: 121 FLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLALEYLHSHN 180
+++++ +FQD L+++M+Y+ GG++ +LL + A+FY E LA+E +H HN
Sbjct: 179 CIVKLYCSFQDEEYLYLIMEYLPGGDMMTLLMRKDTLTEDEARFYVGETVLAIESIHKHN 238
Query: 181 IIYRDLKPENILLDRNGHIKITDFGFAKEV------------------------------ 210
I+RD+KP+N+LLDR+GH+K++DFG K +
Sbjct: 239 YIHRDIKPDNLLLDRSGHMKLSDFGLCKPLDCSILQEKDFVVAHNLSGALQSDGRPVAPR 298
Query: 211 ----------------ITVTWTLCGTPDYIAPEVITTKPYNKSVDWWSLGILIFEMLAGY 254
+ ++ GTPDYIAPEV+ K Y DWWSLG +++EML G+
Sbjct: 299 RTRSQMEQLQNWQRNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGAIMYEMLVGF 358
Query: 255 TPFYDVTPMKTYEKIL--AGEVVYPP--FFHPDVVDLLGKLITADLTRRLGNLQSGPDDI 310
PFY PM T KI+ + +P P+ DL+ +L+ ++ +R+G G ++I
Sbjct: 359 PPFYSDEPMTTCRKIVNWKNYLKFPDEVRLSPEAKDLICRLL-CNVEQRIGT--KGANEI 415
Query: 311 KSHPWFAEVIWEKL 324
K HPWF+ V WEKL
Sbjct: 416 KEHPWFSGVEWEKL 429
>Hs20543401 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 2092
Score = 207 bits (528), Expect = 2e-53
Identities = 113/324 (34%), Positives = 184/324 (55%), Gaps = 26/324 (8%)
Query: 61 DFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRMLKLVEHP 120
DF+ ++ + G++G V+ VR + + +A+K + K +I QI+ ER +L E+P
Sbjct: 38 DFETIKLISNGAYGAVYFVRHKESRQRFAMKKINKQNLILRNQIQQAFVERDILTFAENP 97
Query: 121 FLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLALEYLHSHN 180
F++ M+ +F+ R+L MVM+Y+EGG+ +L++ P +A+ Y AE LALEYLH++
Sbjct: 98 FVVSMYCSFETRRHLCMVMEYVEGGDCATLMKNMGPLPVDMARMYFAETVLALEYLHNYG 157
Query: 181 IIYRDLKPENILLDRNGHIKITDFGFAK-EVITVTWTL-----------------CGTPD 222
I++RDLKP+N+L+ GHIK+TDFG +K ++++T L CGTP+
Sbjct: 158 IVHRDLKPDNLLVTSMGHIKLTDFGLSKVGLMSMTTNLYEGHIEKDAREFLDKQVCGTPE 217
Query: 223 YIAPEVITTKPYNKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFFH- 281
YIAPEVI + Y K VDWW++GI+++E L G PF+ TP + + ++++ E+ +P
Sbjct: 218 YIAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVISDEINWPEKDEA 277
Query: 282 --PDVVDLLGKLITADLTRRLGNLQSGPDDIKSHPWFAEVIWEKLVAKDIETPYEPPIAV 339
PD DL+ L+ + RLG G ++K H +F + W L+ + E P
Sbjct: 278 PPPDAQDLITLLLRQNPLERLGT--GGAYEVKQHRFFRSLDWNSLLRQKAEF---IPQLE 332
Query: 340 GVGDSSLFDQYPEEQLDYGVQGED 363
D+S FD E+ + ED
Sbjct: 333 SEDDTSYFDTRSEKYHHMETEEED 356
>CE02604 [T] KOG0695 Serine/threonine protein kinase
Length = 597
Score = 206 bits (523), Expect = 6e-53
Identities = 112/302 (37%), Positives = 172/302 (56%), Gaps = 18/302 (5%)
Query: 53 SKGKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERR 112
SK +L+DF+++ +G GS+ +V V + YAIK++KK + I+ E+
Sbjct: 244 SKWAVSLNDFRLLTVIGRGSYAKVVQAEHVSTRQIYAIKIIKKEMFNEDEDIDWVQTEKS 303
Query: 113 MLKLVE-HPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTL 171
+ + +PFL+ + FQ LF V++++ GG+L +++ ++ P A+FY+ E+ L
Sbjct: 304 VFEAASNYPFLVGLHSCFQTESRLFFVIEFVPGGDLMFHMQQQRKLPEEHARFYSGEIIL 363
Query: 172 ALEYLHSHNIIYRDLKPENILLDRNGHIKITDFGFAKEVI---TVTWTLCGTPDYIAPEV 228
AL +LHS IIYRDLK +N+L+D GHIK+TD+G KE I +T T CGTP+YIAPE+
Sbjct: 364 ALHFLHSRGIIYRDLKLDNVLIDAEGHIKLTDYGMCKENIKDGDLTSTFCGTPNYIAPEI 423
Query: 229 ITTKPYNKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEK---------ILAGEVVYPPF 279
+ Y SVDWW+LG+L+FEM+AG +PF D+ M+ E+ IL ++ P
Sbjct: 424 LRGDEYGFSVDWWALGVLMFEMMAGRSPF-DIVGMQNSEENTEDYLFQIILERQIRIPRS 482
Query: 280 FHPDVVDLLGKLITADLTRRLG---NLQSGPDDIKSHPWFAEVI-WEKLVAKDIETPYEP 335
+L + D T RLG ++ G D+K H +F I WE L K + PY P
Sbjct: 483 LSVRASGILKGFLNKDPTERLGCKLDINEGLRDMKEHQFFRGFIDWEALEQKAVAPPYHP 542
Query: 336 PI 337
+
Sbjct: 543 AV 544
>At4g14350 [R] KOG0605 NDR and related serine/threonine kinases
Length = 475
Score = 206 bits (523), Expect = 6e-53
Identities = 110/312 (35%), Positives = 168/312 (53%), Gaps = 51/312 (16%)
Query: 61 DFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRMLKLVEHP 120
DF+ + +G G+FG V + R G YA+K LKK +++R Q+EH ER +L V+
Sbjct: 42 DFEPLTMIGKGAFGEVRICREKGTGNVYAMKKLKKSEMLRRGQVEHVKAERNLLAEVDSN 101
Query: 121 FLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLALEYLHSHN 180
+++++ +FQD L+++M+Y+ GG++ +LL + A+FY E LA+E +H HN
Sbjct: 102 CIVKLYCSFQDEEYLYLIMEYLPGGDMMTLLMRKDTLTEDEARFYIGETVLAIESIHKHN 161
Query: 181 IIYRDLKPENILLDRNGHIKITDFGFAKEV---------ITV------------------ 213
I+RD+KP+N+LLD++GH+K++DFG K + TV
Sbjct: 162 YIHRDIKPDNLLLDKDGHMKLSDFGLCKPLDCSNLQEKDFTVARNVSGALQSDGRPVATR 221
Query: 214 -----------------TWTLCGTPDYIAPEVITTKPYNKSVDWWSLGILIFEMLAGYTP 256
++ GTPDYIAPEV+ K Y DWWSLG +++EML G+ P
Sbjct: 222 RTQQEQLLNWQRNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGAIMYEMLVGFPP 281
Query: 257 FYDVTPMKTYEKIL--AGEVVYPP--FFHPDVVDLLGKLITADLTRRLGNLQSGPDDIKS 312
FY PM T KI+ + +P P+ DL+ +L+ ++ +RLG G D+IK
Sbjct: 282 FYSDDPMTTCRKIVNWRNYLKFPDEVRLSPEAKDLICRLL-CNVEQRLGT--KGADEIKG 338
Query: 313 HPWFAEVIWEKL 324
HPWF W KL
Sbjct: 339 HPWFRGTEWGKL 350
>At3g10540 [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 483
Score = 204 bits (520), Expect = 1e-52
Identities = 104/281 (37%), Positives = 166/281 (59%), Gaps = 13/281 (4%)
Query: 57 YTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRMLKL 116
+T HDF++ + G GS+ +V + NG YA+K++ K I + + + ER +L
Sbjct: 37 FTYHDFELGKIYGVGSYSKVVRAKKKDNGTVYALKIMDKKFITKENKTAYVKLERIVLDQ 96
Query: 117 VEHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLALEYL 176
+EHP +++++ TFQD+++L+M ++ EGGELF + + R A+FY+AEV ALEY+
Sbjct: 97 LEHPGIVKLFFTFQDTQSLYMALESCEGGELFDQITRKGRLSEDEARFYSAEVVDALEYI 156
Query: 177 HSHNIIYRDLKPENILLDRNGHIKITDFGFAKEV----ITV---------TWTLCGTPDY 223
H+ +I+RD+KPEN+LL +GHIKI DFG K + ITV T GT Y
Sbjct: 157 HNMGLIHRDIKPENLLLTLDGHIKIADFGSVKPMQDSQITVLPNAASDDKACTFVGTAAY 216
Query: 224 IAPEVITTKPYNKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFFHPD 283
+ PEV+ + P D W+LG +++ML+G +PF D + +++I+A ++ +P F
Sbjct: 217 VPPEVLNSSPATFGNDLWALGCTLYQMLSGTSPFKDASEWLIFQRIIARDIKFPNHFSEA 276
Query: 284 VVDLLGKLITADLTRRLGNLQSGPDDIKSHPWFAEVIWEKL 324
DL+ +L+ D +RR G G D +K HP+F V W+ L
Sbjct: 277 ARDLIDRLLDTDPSRRPGAGSEGYDSLKRHPFFKGVDWKNL 317
>CE20493 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 1370
Score = 203 bits (517), Expect = 3e-52
Identities = 103/292 (35%), Positives = 170/292 (57%), Gaps = 23/292 (7%)
Query: 61 DFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRMLKLVEHP 120
DF +R + G++G V+LVR + +A+K + K ++ Q++ ER +L + ++P
Sbjct: 357 DFDTIRLVSNGAYGAVYLVRHRETRQRFALKKMNKQTLMLRNQVDQVFAERDILTMADNP 416
Query: 121 FLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLALEYLHSHN 180
F++ +G+F+ + L M+M+Y+EGG+ +LL+ + P + + Y AE LA+EYLHS+
Sbjct: 417 FVVSFYGSFETRQYLCMLMEYVEGGDCAALLKSAGTLPVELVRLYVAETILAIEYLHSYG 476
Query: 181 IIYRDLKPENILLDRNGHIKITDFGFAK--------------EVITVTW-----TLCGTP 221
I++RDLKP+N+L+ GHIK+TDFG +K + + T LCGTP
Sbjct: 477 IVHRDLKPDNLLITAMGHIKLTDFGLSKIGLMNRTTLVAEGYDAVVETQQFQDKQLCGTP 536
Query: 222 DYIAPEVITTKPYNKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYP---P 278
+YIAPEVI + Y K VDWW+LGI+++E L G PF+ TP + K+++ +V YP
Sbjct: 537 EYIAPEVILRRGYGKPVDWWALGIILYEFLVGIVPFFGETPEALFSKVISEDVEYPEEDE 596
Query: 279 FFHPDVVDLLGKLITADLTRRLGNLQSGPDDIKSHPWFAEVIWEKLVAKDIE 330
P+ DL +L+ + RLG L +G + +H +F + + L+ + E
Sbjct: 597 ALPPEAADLCRRLLEKNPAERLGTL-NGAAQLMAHEFFILLDFTSLLRQKAE 647
>YCR091w [R] KOG0610 Putative serine/threonine protein kinase
Length = 720
Score = 203 bits (516), Expect = 4e-52
Identities = 118/308 (38%), Positives = 176/308 (56%), Gaps = 32/308 (10%)
Query: 62 FQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRMLKLVEHPF 121
F+ +R LG G G+V+L+R + +A+KVL KH++I+ K+I+ E+ +L +HPF
Sbjct: 324 FEKIRLLGQGDVGKVYLMRERDTNQIFALKVLNKHEMIKRKKIKRVLTEQEILATSDHPF 383
Query: 122 LIRMWGTFQDSRNLFMVMDYIEGGELFSLL--RKSQRFPNPVAKFYAAEVTLALEYLHSH 179
++ ++ +FQ L++ M+Y GGE F L RKS+ AKFYA+EV ALEYLH
Sbjct: 384 IVTLYHSFQTKDYLYLCMEYCMGGEFFRALQTRKSKCIAEEDAKFYASEVVAALEYLHLL 443
Query: 180 NIIYRDLKPENILLDRNGHIKITDFGFA-----------KEVITVTWTLC---------- 218
IYRDLKPENILL ++GH+ ++DF + K+ + +C
Sbjct: 444 GFIYRDLKPENILLHQSGHVMLSDFDLSIQATGSKKPTMKDSTYLDTKICSDGFRTNSFV 503
Query: 219 GTPDYIAPEVITTKPYNKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYP- 277
GT +Y+APEVI + +VDWW+LGILI+EML G TPF +T+ IL +V +P
Sbjct: 504 GTEEYLAPEVIRGNGHTAAVDWWTLGILIYEMLFGCTPFKGDNSNETFSNILTKDVKFPH 563
Query: 278 -PFFHPDVVDLLGKLITADLTRRLGNLQSGPDDIKSHPWFAEVIWEKLVAKDIETPYEPP 336
+ DL+ KL+ + +RLG+ +SG DIK HP+F +V W L +D PP
Sbjct: 564 DKEVSKNCKDLIKKLLNKNEAKRLGS-KSGAADIKRHPFFKKVQWSFLRNQD------PP 616
Query: 337 IAVGVGDS 344
+ + D+
Sbjct: 617 LIPALNDN 624
>7293735 [R] KOG0605 NDR and related serine/threonine kinases
Length = 459
Score = 201 bits (512), Expect = 1e-51
Identities = 109/343 (31%), Positives = 181/343 (51%), Gaps = 50/343 (14%)
Query: 59 LHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRMLKLVE 118
+ DF+ ++ +G G+FG V LV+ G YA+KVL+K ++ +Q+ H ER +L +
Sbjct: 90 VEDFEALKVIGRGAFGEVRLVQKKDTGHVYAMKVLRKADMLEKEQVAHVRAERDVLVEAD 149
Query: 119 HPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLALEYLHS 178
H ++++M+ +FQD NL+++M+++ GG++ +LL K +FY +E LA++ +H
Sbjct: 150 HQWVVKMYYSFQDPVNLYLIMEFLPGGDMMTLLMKKDTLSEEGTQFYISETALAIDSIHK 209
Query: 179 HNIIYRDLKPENILLDRNGHIKITDFG--------------------------------- 205
I+RD+KP+N+LLD GH+K++DFG
Sbjct: 210 LGFIHRDIKPDNLLLDARGHLKLSDFGLCTGLKKSHRTDFYRDLSQAKPSDFIGTCASPM 269
Query: 206 --------FAKEVITVTWTLCGTPDYIAPEVITTKPYNKSVDWWSLGILIFEMLAGYTPF 257
+ + + ++ GTPDYIAPEV Y + DWWSLG++++EML GY PF
Sbjct: 270 DSKRRAESWKRNRRALAYSTVGTPDYIAPEVFLQTGYGPACDWWSLGVIMYEMLMGYPPF 329
Query: 258 YDVTPMKTYEKIL--AGEVVYPPFFHPDVVDLLGKLIT--ADLTRRLGNLQSGPDDIKSH 313
P TY K++ +++PP P + +I + RRLG+ Q G +D+KS
Sbjct: 330 CSDNPQDTYRKVMNWRETLIFPPEI-PISEEAKETIINFCCEADRRLGS-QRGLEDLKSV 387
Query: 314 PWFAEVIWEKLVAKDIETPYEPPIAVGVGDSSLFDQYPEEQLD 356
P+F V WE + + P E + D+S FD++P+ L+
Sbjct: 388 PFFRGVDWEHIRERPAAIPVE---VRSIDDTSNFDEFPDVSLE 427
>SPBC1861.09 [R] KOG0610 Putative serine/threonine protein kinase
Length = 526
Score = 201 bits (511), Expect = 1e-51
Identities = 121/340 (35%), Positives = 182/340 (52%), Gaps = 40/340 (11%)
Query: 52 VSKGKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDER 111
+S+ + T H F+ +R LG G G+V+LVR N R +A+K+L K ++I+ ++ E+
Sbjct: 145 ISRVEVTPHSFEKIRLLGQGDVGKVYLVRQKSNHRLFAMKILNKREMIKRHKVNRVLAEQ 204
Query: 112 RMLKLVEHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQR--FPNPVAKFYAAEV 169
+L +HPF++ ++ +FQ L++ M+Y GGE F L + P A FYAAEV
Sbjct: 205 EILTKSKHPFIVTLYHSFQSRDYLYLCMEYCAGGEFFRALHSLPKHILPEKDACFYAAEV 264
Query: 170 TLALEYLHSHNIIYRDLKPENILLDRNGHIKITDFGFAKEVITVTW-------------- 215
T ALEYLH IYRDLKPENILL ++GHI ++DF +K + VT
Sbjct: 265 TAALEYLHLMGFIYRDLKPENILLHQSGHIMLSDFDLSKPISIVTHPTVVLPKHSTFSQE 324
Query: 216 ----------------TLCGTPDYIAPEVITTKPYNKSVDWWSLGILIFEMLAGYTPFYD 259
+ GT +YIAPEVI + + +VDWW+LGI I+E+L G TPF
Sbjct: 325 KPALDTNSYFSNFRTNSFVGTEEYIAPEVIRSCGHTVAVDWWTLGIFIYEILYGTTPFKG 384
Query: 260 VTPMKTYEKILAGEVVYPPFF-HPDV----VDLLGKLITADLTRRLGNLQSGPDDIKSHP 314
T+ IL +V +P + P+V L+ +L+ D ++R G++ +G DIK HP
Sbjct: 385 KNRHATFSNILYSDVSFPEYHGAPNVSSTCKSLIRRLLVKDESKRCGSV-AGASDIKQHP 443
Query: 315 WFAEVIWEKLVAKDIETPYEPPIAVGVGDSSLFDQYPEEQ 354
+F + W L + ++ P P I G+ D EE+
Sbjct: 444 FFRHIQWALL--RSMKPPIIPKIEDGMEAVEPSDNDNEEE 481
>ECU07g0520 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 322
Score = 201 bits (511), Expect = 1e-51
Identities = 103/279 (36%), Positives = 168/279 (59%), Gaps = 4/279 (1%)
Query: 59 LHDFQIMRTLGTGSFGRVHLVRSVHNGR-YYAIKVLKKHQIIRMKQIEHTNDERRMLKLV 117
+ DF+ ++ +G G+FG+VHLVR + +A+K+L +I+R + + +E +LK +
Sbjct: 4 IQDFEFVKVVGVGAFGKVHLVRLKSSPTSVFAMKMLDFGEILRQRLADQLENEISILKRI 63
Query: 118 EH-PFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLALEYL 176
PF+ +++ T + ++M+Y+ GGELF L+K RF +A+FYAAE+ AL ++
Sbjct: 64 YGCPFVAKLYSTDFHGGKVGLIMEYVGGGELFYWLKKCGRFDEQMARFYAAEIISALRFI 123
Query: 177 HSHNIIYRDLKPENILLDRNGHIKITDFGFAKEVITVTWTLCGTPDYIAPEVITTKPYNK 236
H I+YRDLKPENIL+ GHIK+ DFGF+ + + GTP+Y++PE + ++ +
Sbjct: 124 HGRGILYRDLKPENILITSTGHIKLIDFGFSVYESENIYMISGTPEYMSPEKLRSEDDGR 183
Query: 237 SVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFFHPDVVDLLGKLITADL 296
+ D+W LG++I+EML G PFYD + Y KIL VV+P + P L+ L+ +
Sbjct: 184 ASDYWGLGVMIYEMLCGDPPFYDSSADAIYHKILESNVVFPHYVSPVARCLITGLLDKNR 243
Query: 297 TRRLGNLQSGPDDIKSHPWFAEVIWEKLVAKDIETPYEP 335
RLG G +I HP+F + W ++ ++ IE P+ P
Sbjct: 244 ATRLGT--KGICEIMGHPFFKGIDWHEVESRRIEPPFIP 280
>At1g48490 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 1244
Score = 201 bits (511), Expect = 1e-51
Identities = 107/302 (35%), Positives = 170/302 (55%), Gaps = 33/302 (10%)
Query: 54 KGKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRM 113
+ + ++ DF++M+++ G+FG V L R G +AIKVL+K +IR +E ER +
Sbjct: 820 RDRISIDDFEVMKSISRGAFGHVILARKNTTGDLFAIKVLRKADMIRKNAVESILAERDI 879
Query: 114 LKLVEHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLAL 173
L +PF++R + +F S NL++VM+Y+ GG+ +S+LRK A+ Y AEV LAL
Sbjct: 880 LINARNPFVVRFFYSFTCSENLYLVMEYLNGGDFYSMLRKIGCLDEANARVYIAEVVLAL 939
Query: 174 EYLHSHNIIYRDLKPENILLDRNGHIKITDFGFAK------------EVITVTWTL---- 217
EYLHS +++RDLKP+N+L+ +GH+K+TDFG +K V + T L
Sbjct: 940 EYLHSEGVVHRDLKPDNLLIAHDGHVKLTDFGLSKVGLINNTDDLSGPVSSATSLLVEEK 999
Query: 218 ------------CGTPDYIAPEVITTKPYNKSVDWWSLGILIFEMLAGYTPFYDVTPMKT 265
GTPDY+APE++ + + DWWS+GI+++E L G PF P +
Sbjct: 1000 PKLPTLDHKRSAVGTPDYLAPEILLGTGHGATADWWSVGIILYEFLVGIPPFNADHPQQI 1059
Query: 266 YEKILAGEVVYPPF---FHPDVVDLLGKLITADLTRRLGNLQSGPDDIKSHPWFAEVIWE 322
++ IL + +PP + DL+ +L+T D +RLG G ++K H +F ++ W
Sbjct: 1060 FDNILNRNIQWPPVPEDMSHEARDLIDRLLTEDPHQRLG--ARGAAEVKQHSFFKDIDWN 1117
Query: 323 KL 324
L
Sbjct: 1118 TL 1119
>YNR047w [R] KOG0610 Putative serine/threonine protein kinase
Length = 893
Score = 200 bits (508), Expect = 3e-51
Identities = 120/305 (39%), Positives = 172/305 (56%), Gaps = 31/305 (10%)
Query: 62 FQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRMLKLVEHPF 121
F+ +R LG G G+V LVR R YA+KVL K ++I+ +I+ E+ +L HPF
Sbjct: 496 FEKIRLLGQGDVGKVFLVREKKTNRVYALKVLSKDEMIKRNKIKRVLTEQEILATSNHPF 555
Query: 122 LIRMWGTFQDSRNLFMVMDYIEGGELFSLL--RKSQRFPNPVAKFYAAEVTLALEYLHSH 179
++ ++ +FQ L++ M+Y GGE F L RK++ A+FYA+EVT ALEYLH
Sbjct: 556 IVTLYHSFQSEDYLYLCMEYCMGGEFFRALQTRKTKCICEDDARFYASEVTAALEYLHLL 615
Query: 180 NIIYRDLKPENILLDRNGHIKITDF---------------GFAKEVITVTW--------- 215
IYRDLKPENILL ++GHI ++DF G A+ + T
Sbjct: 616 GFIYRDLKPENILLHQSGHIMLSDFDLSIQAKDSKVPVVKGSAQSTLVDTKICSDGFRTN 675
Query: 216 TLCGTPDYIAPEVITTKPYNKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVV 275
+ GT +YIAPEVI + +VDWW+LGILI+EML G+TPF +T+ IL EV
Sbjct: 676 SFVGTEEYIAPEVIRGNGHTAAVDWWTLGILIYEMLFGFTPFKGDNTNETFTNILKNEVS 735
Query: 276 YP--PFFHPDVVDLLGKLITADLTRRLGNLQSGPDDIKSHPWFAEVIWEKLVAKDIETPY 333
+P DL+ KL+T + ++RLG + G D+K HP+F +V W L ++ E P
Sbjct: 736 FPNNNEISRTCKDLIKKLLTKNESKRLG-CKMGAADVKKHPFFKKVQWSLL--RNQEPPL 792
Query: 334 EPPIA 338
P ++
Sbjct: 793 IPVLS 797
>Hs4885583 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1354
Score = 198 bits (503), Expect = 1e-50
Identities = 116/335 (34%), Positives = 193/335 (56%), Gaps = 19/335 (5%)
Query: 31 SQSTDYLLAQQKESLLPQRSTVSKGKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAI 90
+++ D L++ K+++ R K + D+++++ +G G+FG V LVR + YA+
Sbjct: 49 NKNIDNFLSRYKDTINKIRDLRMKAE----DYEVVKVIGRGAFGEVQLVRHKSTRKVYAM 104
Query: 91 KVLKKHQIIRMKQIEHTNDERRMLKLVEHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSL 150
K+L K ++I+ +ER ++ P++++++ FQD R L+MVM+Y+ GG+L +L
Sbjct: 105 KLLSKFEMIKRSDSAFFWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNL 164
Query: 151 LRKSQRFPNPVAKFYAAEVTLALEYLHSHNIIYRDLKPENILLDRNGHIKITDFG----F 206
+ + P A+FY AEV LAL+ +HS I+RD+KP+N+LLD++GH+K+ DFG
Sbjct: 165 M-SNYDVPEKWARFYTAEVVLALDAIHSMGFIHRDVKPDNMLLDKSGHLKLADFGTCMKM 223
Query: 207 AKEVITVTWTLCGTPDYIAPEVITTKP----YNKSVDWWSLGILIFEMLAGYTPFYDVTP 262
KE + T GTPDYI+PEV+ ++ Y + DWWS+G+ ++EML G TPFY +
Sbjct: 224 NKEGMVRCDTAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADSL 283
Query: 263 MKTYEKIL--AGEVVYPPFFHPDVVDLLGKLITADLTRRLGNL-QSGPDDIKSHPWFAEV 319
+ TY KI+ + +P D+ LI A LT R L ++G ++IK H +F
Sbjct: 284 VGTYSKIMNHKNSLTFPD--DNDISKEAKNLICAFLTDREVRLGRNGVEEIKRHLFFKND 341
Query: 320 IWEKLVAKDIETPYEPPIAVGVGDSSLFDQYPEEQ 354
W +D P P ++ + D+S FD E++
Sbjct: 342 QWAWETLRDTVAPVVPDLSSDI-DTSNFDDLEEDK 375
>7294265 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 2139
Score = 197 bits (502), Expect = 2e-50
Identities = 109/326 (33%), Positives = 187/326 (56%), Gaps = 27/326 (8%)
Query: 60 HDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRMLKLVEH 119
+DF I++ + G++G V+LV+ + +A+K + K+ +I Q+E ER +L ++
Sbjct: 833 NDFDIVKLISNGAYGAVYLVKHKTTRQRFAMKKINKNNLILRNQVEQVFAERDILSFADN 892
Query: 120 PFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLALEYLHSH 179
PF++ M+ +F+ ++L +VM+Y+EGG+ +LL+ P +A+FY AE LA+EYLHS+
Sbjct: 893 PFVVSMYCSFETKKHLCLVMEYVEGGDCGTLLKNIGPLPADMARFYFAETVLAVEYLHSY 952
Query: 180 NIIYRDLKPENILLDRNGHIKITDFGFAKEVITVTWT------------------LCGTP 221
I++RDLKP+N+L+ GHIK+TDFG +K + T + GTP
Sbjct: 953 GIVHRDLKPDNLLITALGHIKLTDFGLSKMGLMSLATNLYEGYIDSETRQFSDKQVYGTP 1012
Query: 222 DYIAPEVITTKPYNKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPF-- 279
+YIAPEVI + Y K VDWWS+GI+++E L G PF+ T + + + ++ +P
Sbjct: 1013 EYIAPEVILRQGYGKPVDWWSMGIILYEFLIGCVPFFGETTEELFAHTVNDDIEWPDSED 1072
Query: 280 --FHPDVVDLLGKLITADLTRRLGNLQSGPDDIKSHPWFAEVIWEKLVAKDIETPYEPPI 337
+ D++ +L+ + RLG QSG ++K H +F + W L+ + E + P +
Sbjct: 1073 WPVQAEAKDIISQLLQQNPRDRLGT-QSGALEMKEHEYFLGMDWNSLLRQKAE--FVPQL 1129
Query: 338 AVGVGDSSLFDQYPEEQLDYGVQGED 363
+ D+S FD ++ ++ + GED
Sbjct: 1130 SHD-DDTSYFDT-RMDRYNHDLGGED 1153
>Hs6005814 [R] KOG0605 NDR and related serine/threonine kinases
Length = 465
Score = 196 bits (499), Expect = 4e-50
Identities = 109/339 (32%), Positives = 178/339 (52%), Gaps = 48/339 (14%)
Query: 59 LHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRMLKLVE 118
L DF+ ++ +G G+FG V LV+ G YA+K+L+K ++ +Q+ H ER +L +
Sbjct: 86 LEDFESLKVIGRGAFGEVRLVQKKDTGHVYAMKILRKADMLEKEQVGHIRAERDILVEAD 145
Query: 119 HPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLALEYLHS 178
++++M+ +FQD NL+++M+++ GG++ +LL K +FY AE LA++ +H
Sbjct: 146 SLWVVKMFYSFQDKLNLYLIMEFLPGGDMMTLLMKKDTLTEEETQFYIAETVLAIDSIHQ 205
Query: 179 HNIIYRDLKPENILLDRNGHIKITDFGFAKEVITV------------------------- 213
I+RD+KP+N+LLD GH+K++DFG +
Sbjct: 206 LGFIHRDIKPDNLLLDSKGHVKLSDFGLCTGLKKAHRTEFYRNLNHSLPSDFTFQNMNSK 265
Query: 214 ----TW---------TLCGTPDYIAPEVITTKPYNKSVDWWSLGILIFEMLAGYTPFYDV 260
TW + GTPDYIAPEV YNK DWWSLG++++EML GY PF
Sbjct: 266 RKAETWKRNRRQLAFSTVGTPDYIAPEVFMQTGYNKLCDWWSLGVIMYEMLIGYPPFCSE 325
Query: 261 TPMKTYEKILAGE--VVYPPF--FHPDVVDLLGKLITADLTRRLGNLQSGPDDIKSHPWF 316
TP +TY+K++ + + +PP DL+ + + R+G G ++IKS+ +F
Sbjct: 326 TPQETYKKVMNWKETLTFPPEVPISEKAKDLILR-FCCEWEHRIG--APGVEEIKSNSFF 382
Query: 317 AEVIWEKLVAKDIETPYEPPIAVGVGDSSLFDQYPEEQL 355
V WE + + E + D+S FD++PE +
Sbjct: 383 EGVDWEHIRERPAAISIE---IKSIDDTSNFDEFPESDI 418
>CE05507 [T] KOG0603 Ribosomal protein S6 kinase
Length = 785
Score = 196 bits (499), Expect = 4e-50
Identities = 113/298 (37%), Positives = 177/298 (58%), Gaps = 19/298 (6%)
Query: 56 KYTLHDFQIMRTLGTGSFGRVHLVRSV----HNGRYYAIKVLKKHQII-RMKQIEHTNDE 110
K ++ +F ++R LG G++G+V LVR V HN YA+KVL+K +++ + K +EHT E
Sbjct: 11 KVSMENFALLRVLGKGAYGKVFLVRKVGGKDHN-TIYAMKVLRKTRVLTKQKTLEHTMAE 69
Query: 111 RRML-KLVEHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEV 169
R++L +L PFL+ ++ FQ L +VM+Y+ GGELF+ L F A+F AE+
Sbjct: 70 RQVLERLRGTPFLVNLFYAFQTDTKLHIVMEYVRGGELFTHLCSRGHFDLEAARFVIAEL 129
Query: 170 TLALEYLHSHNIIYRDLKPENILLDRNGHIKITDFGFAKEVITVTW----TLCGTPDYIA 225
+A++ LH +IYRDLK ENILLD GH+K+TDFG +K + + CGT +Y++
Sbjct: 130 VVAIDSLHQRKVIYRDLKLENILLDEEGHVKLTDFGLSKLFLPGELDRANSYCGTIEYMS 189
Query: 226 PEVITTKP--YNKSVDWWSLGILIFEMLAGYTPF----YDVTPMKTYEKILAGEVVYPPF 279
PEVI Y+ VDWWSLG++ FE+L G +PF + ++I+ +V +P
Sbjct: 190 PEVINRPEGGYSDVVDWWSLGVISFELLTGCSPFTVDGAQNSSKDIAKRIMTKKVPFPKT 249
Query: 280 FHPDVVDLLGKLITADLTRRLGNLQSGPDDIKSHPWFAEVIWEKLVAKDIETPYEPPI 337
D D +G+L+ L +RLG +G D+IK+H + + + W+ V + ++ P I
Sbjct: 250 MDVDARDFIGQLLEKKLEKRLG--YNGVDEIKNHKFMSSIDWDAAVKRTLKPVIVPRI 305
Score = 117 bits (294), Expect = 2e-26
Identities = 92/341 (26%), Positives = 156/341 (44%), Gaps = 62/341 (18%)
Query: 37 LLAQQKESLLPQRSTVSKGKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKH 96
L+A+ +LL S +K K D + LG G+F V V +G +A+K
Sbjct: 360 LMAEDVNALLASSSFFAKYKLDKSDAGL---LGKGAFSVVRRCERVVDGAQFAVK----- 411
Query: 97 QIIRMKQIEHTNDERRMLKLVE-HPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQ 155
I+ K E R+L++V+ HP ++++ D + ++VM+ + G EL +RK +
Sbjct: 412 -IVSQKFASQAQREARILEMVQGHPNIVQLHDVHSDPLHFYLVMEILTGNELLERIRKLE 470
Query: 156 RFPNPVAKFYAAEVTLALEYLHSHNIIYRDLKPENIL---LDRNGHIKITDFGFAK---- 208
RF A ++ A++YLH I++RDLKPENIL +D + +++ DFGFA+
Sbjct: 471 RFTESEAADIMRQLVSAVKYLHDKRIVHRDLKPENILFESIDSSARLRLVDFGFARLLPN 530
Query: 209 ---------EVITVTW------------TLCGTPDYIAPEVI----TTKPYNKSVDWWSL 243
+V+ + T C T Y APEV+ + YN+ D WSL
Sbjct: 531 SMEQQLKSVQVLRKMYGLIAHNHSLHSETPCFTLQYAAPEVLDVGDSQPEYNEQCDLWSL 590
Query: 244 GILIFEMLAGYTPFY----DVTPMKTYEKILAGEVVYP----PFFHPDVVDLLGKLITAD 295
G+++F ML+G PF+ + + ++I E + D +L+ L+T D
Sbjct: 591 GVVLFTMLSGQVPFHARSRQESATEIMQRICRAEFSFTGDAWTNVSADAKNLITGLLTVD 650
Query: 296 LTRRLGNLQSGPDDIKSHPWFAEVIWEKLVAKDIETPYEPP 336
+RL ++ +H W + ++TP + P
Sbjct: 651 PKKRL-----SMQELTAHMWLKS-------SASMDTPLQTP 679
>At5g04510 [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 488
Score = 196 bits (499), Expect = 4e-50
Identities = 103/281 (36%), Positives = 161/281 (56%), Gaps = 13/281 (4%)
Query: 57 YTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRMLKL 116
+T HDF+ + G GS+ +V + G YA+K++ K I + + + ER +L
Sbjct: 36 FTSHDFEFGKIYGVGSYSKVVRAKKKETGTVYALKIMDKKFITKENKTAYVKLERIVLDQ 95
Query: 117 VEHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLALEYL 176
+EHP +I+++ TFQD+ +L+M ++ EGGELF + + R A+FY AEV ALEY+
Sbjct: 96 LEHPGIIKLYFTFQDTSSLYMALESCEGGELFDQITRKGRLSEDEARFYTAEVVDALEYI 155
Query: 177 HSHNIIYRDLKPENILLDRNGHIKITDFGFAKEV----ITV---------TWTLCGTPDY 223
HS +I+RD+KPEN+LL +GHIKI DFG K + ITV T GT Y
Sbjct: 156 HSMGLIHRDIKPENLLLTSDGHIKIADFGSVKPMQDSQITVLPNAASDDKACTFVGTAAY 215
Query: 224 IAPEVITTKPYNKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFFHPD 283
+ PEV+ + P D W+LG +++ML+G +PF D + +++I+A ++ +P F
Sbjct: 216 VPPEVLNSSPATFGNDLWALGCTLYQMLSGTSPFKDASEWLIFQRIIARDIKFPNHFSEA 275
Query: 284 VVDLLGKLITADLTRRLGNLQSGPDDIKSHPWFAEVIWEKL 324
DL+ +L+ + +RR G G +K HP+F V W+ L
Sbjct: 276 ARDLIDRLLDTEPSRRPGAGSEGYVALKRHPFFNGVDWKNL 316
>Hs4759044 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1388
Score = 196 bits (498), Expect = 5e-50
Identities = 109/307 (35%), Positives = 181/307 (58%), Gaps = 15/307 (4%)
Query: 61 DFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRMLKLVEHP 120
D+ +++ +G G+FG V LVR + + YA+K+L K ++I+ +ER ++ P
Sbjct: 91 DYDVVKVIGRGAFGEVQLVRHKASQKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANSP 150
Query: 121 FLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLALEYLHSHN 180
++++++ FQD R L+MVM+Y+ GG+L +L+ + P AKFY AEV LAL+ +HS
Sbjct: 151 WVVQLFYAFQDDRYLYMVMEYMPGGDLVNLM-SNYDVPEKWAKFYTAEVVLALDAIHSMG 209
Query: 181 IIYRDLKPENILLDRNGHIKITDFGFAKEVITVTWTLC----GTPDYIAPEVITTKP--- 233
+I+RD+KP+N+LLD++GH+K+ DFG ++ C GTPDYI+PEV+ ++
Sbjct: 210 LIHRDVKPDNMLLDKHGHLKLADFGTCMKMDETGMVHCDTAVGTPDYISPEVLKSQGGDG 269
Query: 234 -YNKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKIL--AGEVVYPPFFHPDVVDLLGK 290
Y + DWWS+G+ ++EML G TPFY + + TY KI+ + +P ++
Sbjct: 270 FYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMDHKNSLCFPE--DAEISKHAKN 327
Query: 291 LITADLTRRLGNL-QSGPDDIKSHPWFAEVIWEKLVAKDIETPYEPPIAVGVGDSSLFDQ 349
LI A LT R L ++G ++I+ HP+F W ++ P P ++ + DSS FD
Sbjct: 328 LICAFLTDREVRLGRNGVEEIRQHPFFKNDQWHWDNIRETAAPVVPELSSDI-DSSNFDD 386
Query: 350 YPEEQLD 356
+++ D
Sbjct: 387 IEDDKGD 393
>Hs20536595 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1388
Score = 196 bits (498), Expect = 5e-50
Identities = 109/307 (35%), Positives = 181/307 (58%), Gaps = 15/307 (4%)
Query: 61 DFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRMLKLVEHP 120
D+ +++ +G G+FG V LVR + + YA+K+L K ++I+ +ER ++ P
Sbjct: 91 DYDVVKVIGRGAFGEVQLVRHKASQKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANSP 150
Query: 121 FLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLALEYLHSHN 180
++++++ FQD R L+MVM+Y+ GG+L +L+ + P AKFY AEV LAL+ +HS
Sbjct: 151 WVVQLFYAFQDDRYLYMVMEYMPGGDLVNLM-SNYDVPEKWAKFYTAEVVLALDAIHSMG 209
Query: 181 IIYRDLKPENILLDRNGHIKITDFGFAKEVITVTWTLC----GTPDYIAPEVITTKP--- 233
+I+RD+KP+N+LLD++GH+K+ DFG ++ C GTPDYI+PEV+ ++
Sbjct: 210 LIHRDVKPDNMLLDKHGHLKLADFGTCMKMDETGMVHCDTAVGTPDYISPEVLKSQGGDG 269
Query: 234 -YNKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKIL--AGEVVYPPFFHPDVVDLLGK 290
Y + DWWS+G+ ++EML G TPFY + + TY KI+ + +P ++
Sbjct: 270 FYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMDHKNSLCFPE--DAEISKHAKN 327
Query: 291 LITADLTRRLGNL-QSGPDDIKSHPWFAEVIWEKLVAKDIETPYEPPIAVGVGDSSLFDQ 349
LI A LT R L ++G ++I+ HP+F W ++ P P ++ + DSS FD
Sbjct: 328 LICAFLTDREVRLGRNGVEEIRQHPFFKNDQWHWDNIRETAAPVVPELSSDI-DSSNFDD 386
Query: 350 YPEEQLD 356
+++ D
Sbjct: 387 IEDDKGD 393
>At3g17850 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 1263
Score = 196 bits (497), Expect = 6e-50
Identities = 106/308 (34%), Positives = 171/308 (55%), Gaps = 39/308 (12%)
Query: 54 KGKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRM 113
+ + ++ DF+I++ + G+FGRV L + G +AIKVLKK +IR +E ER +
Sbjct: 882 RDRTSIDDFEIIKPISRGAFGRVFLAKKRTTGDLFAIKVLKKADMIRKNAVESILAERDI 941
Query: 114 LKLVEHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLAL 173
L V +PF++R + +F NL++VM+Y+ GG+L+SLLR + + Y AEV LAL
Sbjct: 942 LINVRNPFVVRFFYSFTCRDNLYLVMEYLNGGDLYSLLRNLGCLEEDIVRVYIAEVVLAL 1001
Query: 174 EYLHSHNIIYRDLKPENILLDRNGHIKITDFGFAK-EVITVTWTLC-------------- 218
EYLHS +++RDLKP+N+L+ +GHIK+TDFG +K +I T L
Sbjct: 1002 EYLHSEGVVHRDLKPDNLLIAHDGHIKLTDFGLSKVGLINSTDDLAGPAVSGTSLLDEEE 1061
Query: 219 -------------------GTPDYIAPEVITTKPYNKSVDWWSLGILIFEMLAGYTPFYD 259
GTPDY+APE++ + + DWWS+GI++FE++ G PF
Sbjct: 1062 SRLAASEEQLERRKKRSAVGTPDYLAPEILLGTGHGATADWWSVGIILFELIVGIPPFNA 1121
Query: 260 VTPMKTYEKILAGEVVYPPF---FHPDVVDLLGKLITADLTRRLGNLQSGPDDIKSHPWF 316
P + ++ IL ++ +P + D++ + +T D +RLG G ++K H +F
Sbjct: 1122 EHPQQIFDNILNRKIPWPHVPEEMSAEAHDIIDRFLTEDPHQRLG--ARGAAEVKQHIFF 1179
Query: 317 AEVIWEKL 324
++ W+ L
Sbjct: 1180 KDINWDTL 1187
>SPAC4G8.05 [R] KOG0610 Putative serine/threonine protein kinase
Length = 566
Score = 194 bits (493), Expect = 2e-49
Identities = 122/345 (35%), Positives = 177/345 (50%), Gaps = 47/345 (13%)
Query: 38 LAQQKESLLPQRSTVSKGKYTLHD-------FQIMRTLGTGSFGRVHLVRSVHNGRYYAI 90
LA K+++ + T S + D F+ + LG G GRV+LVR +G++YA+
Sbjct: 164 LAHIKKTVATRARTYSSNSIKICDVEVGPSSFEKVFLLGKGDVGRVYLVREKKSGKFYAM 223
Query: 91 KVLKKHQIIRMKQIEHTNDERRMLKLVEHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSL 150
KVL K ++I+ + + E+ +L HPF++ ++ +FQ L++ M+Y GGE F
Sbjct: 224 KVLSKQEMIKRNKSKRAFAEQHILATSNHPFIVTLYHSFQSDEYLYLCMEYCMGGEFFRA 283
Query: 151 L--RKSQRFPNPVAKFYAAEVTLALEYLHSHNIIYRDLKPENILLDRNGHIKITDFGFAK 208
L R + AKFY AEVT ALEYLH IYRDLKPENILL +GHI ++DF +K
Sbjct: 284 LQRRPGRCLSENEAKFYIAEVTAALEYLHLMGFIYRDLKPENILLHESGHIMLSDFDLSK 343
Query: 209 EVITV------------------------------TWTLCGTPDYIAPEVITTKPYNKSV 238
+ + T + GT +YIAPEVI + +V
Sbjct: 344 QSNSAGAPTVIQARNAPSAQNAYALDTKSCIADFRTNSFVGTEEYIAPEVIKGCGHTSAV 403
Query: 239 DWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFFHPDVV-----DLLGKLIT 293
DWW+LGIL +EML TPF T+ IL +V++P + + +L+ KL+
Sbjct: 404 DWWTLGILFYEMLYATTPFKGKNRNMTFSNILHKDVIFPEYADAPSISSLCKNLIRKLLV 463
Query: 294 ADLTRRLGNLQSGPDDIKSHPWFAEVIWEKLVAKDIETPYEPPIA 338
D RLG+ Q+G D+K HP+F V W L + E P P +A
Sbjct: 464 KDENDRLGS-QAGAADVKLHPFFKNVQWALL--RHTEPPIIPKLA 505
>Hs4505831 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 496
Score = 194 bits (492), Expect = 2e-49
Identities = 113/317 (35%), Positives = 189/317 (58%), Gaps = 21/317 (6%)
Query: 47 PQRSTVSKGKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEH 106
P S V + + DF+I++ +G G+FG V +V+ + + +A+K+L K ++++ +
Sbjct: 62 PFTSKVKQMRLHREDFEILKVIGRGAFGEVAVVKLKNADKVFAMKILNKWEMLKRAETAC 121
Query: 107 TNDERRMLKLVEHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRK-SQRFPNPVAKFY 165
+ER +L ++ ++ + FQD NL++VMDY GG+L +LL K R P +A+FY
Sbjct: 122 FREERDVLVNGDNKWITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKFEDRLPEDMARFY 181
Query: 166 AAEVTLALEYLHSHNIIYRDLKPENILLDRNGHIKITDFGFAKEVI---TVTWTLC-GTP 221
AE+ +A++ +H + ++RD+KP+NIL+D NGHI++ DFG +++ TV ++ GTP
Sbjct: 182 LAEMVIAIDSVHQLHYVHRDIKPDNILMDMNGHIRLADFGSCLKLMEDGTVQSSVAVGTP 241
Query: 222 DYIAPEVITTKP-----YNKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVY 276
DYI+PE++ Y DWWSLG+ ++EML G TPFY + ++TY KI+ + +
Sbjct: 242 DYISPEILQAMEDGKGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKERF 301
Query: 277 P-PFFHPDV----VDLLGKLITADLTRRLGNLQSGPDDIKSHPWFAEVIWEKLVAKDIET 331
P DV DL+ +LI RLG Q+G +D K HP+F+ + W+ + ++ E
Sbjct: 302 QFPAQVTDVSENAKDLIRRLI-CSREHRLG--QNGIEDFKKHPFFSGIDWDNI--RNCEA 356
Query: 332 PYEPPIAVGVGDSSLFD 348
PY P ++ D+S FD
Sbjct: 357 PYIPEVS-SPTDTSNFD 372
>Hs16357474_1 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1530
Score = 192 bits (488), Expect = 7e-49
Identities = 113/329 (34%), Positives = 186/329 (56%), Gaps = 21/329 (6%)
Query: 35 DYLLAQQKESLLPQRSTVSKGKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLK 94
D +A+ E P V + + DF+I++ +G G+FG V +V+ + R YA+K+L
Sbjct: 49 DKYVAEFLEWAKPFTQLVKEMQLHREDFEIIKVIGRGAFGEVAVVKMKNTERIYAMKILN 108
Query: 95 KHQIIRMKQIEHTNDERRMLKLVEHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRK- 153
K ++++ + +ER +L + ++ + FQD +L++VMDY GG+L +LL K
Sbjct: 109 KWEMLKRAETACFREERDVLVNGDCQWITALHYAFQDENHLYLVMDYYVGGDLLTLLSKF 168
Query: 154 SQRFPNPVAKFYAAEVTLALEYLHSHNIIYRDLKPENILLDRNGHIKITDFGFAKEV--- 210
+ P +A+FY E+ LA++ +H + ++RD+KP+N+LLD NGHI++ DFG ++
Sbjct: 169 EDKLPEDMARFYIGEMVLAIDSIHQLHYVHRDIKPDNVLLDVNGHIRLADFGSCLKMNDD 228
Query: 211 -ITVTWTLCGTPDYIAPEVITTK-----PYNKSVDWWSLGILIFEMLAGYTPFYDVTPMK 264
+ GTPDYI+PE++ Y DWWSLG+ ++EML G TPFY + ++
Sbjct: 229 GTVQSSVAVGTPDYISPEILQAMEDGMGKYGPECDWWSLGVCMYEMLYGETPFYAESLVE 288
Query: 265 TYEKILAGEVVYPPFFH-----PDVVDLLGKLITADLTRRLGNLQSGPDDIKSHPWFAEV 319
TY KI+ E + H + DL+ +LI RRLG Q+G +D K H +F +
Sbjct: 289 TYGKIMNHEERFQFPSHVTDVSEEAKDLIQRLI-CSRERRLG--QNGIEDFKKHAFFEGL 345
Query: 320 IWEKLVAKDIETPYEPPIAVGVGDSSLFD 348
WE + +++E PY P ++ D+S FD
Sbjct: 346 NWENI--RNLEAPYIPDVS-SPSDTSNFD 371
>CE11916 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1548
Score = 191 bits (484), Expect = 2e-48
Identities = 112/327 (34%), Positives = 179/327 (54%), Gaps = 21/327 (6%)
Query: 38 LAQQKESLLPQRSTVSKGKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQ 97
+A+ ES+ S K + + DF++++ +G G+FG V +VR G YA+K+L K +
Sbjct: 59 IAEFVESVKTVISKAKKLRLSRDDFEVLKVIGKGAFGEVAVVRMRGVGEIYAMKILNKWE 118
Query: 98 IIRMKQIEHTNDERRMLKLVEHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRK-SQR 156
+++ + +ER +L + ++ + FQD +NL+ VMDY GG++ +LL K
Sbjct: 119 MVKRAETACFREERDVLVYGDRRWITNLHYAFQDEKNLYFVMDYYIGGDMLTLLSKFVDH 178
Query: 157 FPNPVAKFYAAEVTLALEYLHSHNIIYRDLKPENILLDRNGHIKITDFGFAKEVI----T 212
P +AKFY AE+ LA++ LH ++RD+KP+N+LLD GHI++ DFG ++
Sbjct: 179 IPESMAKFYIAEMVLAIDSLHRLGYVHRDVKPDNVLLDMQGHIRLADFGSCLRILADGSV 238
Query: 213 VTWTLCGTPDYIAPEVITTKP-----YNKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYE 267
+ GTPDYI+PE++ Y K DWWSLGI ++EML G TPFY + TY
Sbjct: 239 ASNVAVGTPDYISPEILRAMEDGRGRYGKECDWWSLGICMYEMLYGTTPFYSERLVDTYG 298
Query: 268 KILAGEVVYPPFFHPDVVDLLGKLITADLTRRL------GNLQSGPDDIKSHPWFAEVIW 321
KI++ + + F D +D + DL R+L ++G D + HP+F + W
Sbjct: 299 KIMSHQDMLD--FPDDEIDWVVSEEAKDLIRQLICSSDVRFGRNGLSDFQLHPFFEGIDW 356
Query: 322 EKLVAKDIETPYEPPIAVGVGDSSLFD 348
+ +D PY P ++ D+S FD
Sbjct: 357 NTI--RDSNPPYVPEVS-SPEDTSNFD 380
>Hs4758666 [D] KOG0608 Warts/lats-like serine threonine kinases
Length = 1130
Score = 189 bits (480), Expect = 6e-48
Identities = 120/348 (34%), Positives = 180/348 (51%), Gaps = 59/348 (16%)
Query: 62 FQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRMLKLVEHPF 121
F ++TLG G+FG V L R V YA K L+K ++ Q+ H ER +L ++ +
Sbjct: 705 FVKIKTLGIGAFGEVCLARKVDTKALYATKTLRKKDVLLRNQVAHVKAERDILAEADNEW 764
Query: 122 LIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLALEYLHSHNI 181
++R++ +FQD NL+ VMDYI GG++ SLL + FP +A+FY AE+T A+E +H
Sbjct: 765 VVRLYYSFQDKDNLYFVMDYIPGGDMMSLLIRMGIFPESLARFYIAELTCAVESVHKMGF 824
Query: 182 IYRDLKPENILLDRNGHIKITDFG--------------------------FAKEVITVTW 215
I+RD+KP+NIL+DR+GHIK+TDFG F+ E +
Sbjct: 825 IHRDIKPDNILIDRDGHIKLTDFGLCTGFRWTHDSKYYQSGDHPRQDSMDFSNEWGDPSS 884
Query: 216 TLCG------------------------TPDYIAPEVITTKPYNKSVDWWSLGILIFEML 251
CG TP+YIAPEV+ Y + DWWS+G+++FEML
Sbjct: 885 CRCGDRLKPLERRAARQHQRCLAHSLVGTPNYIAPEVLLRTGYTQLCDWWSVGVILFEML 944
Query: 252 AGYTPFYDVTPMKTYEKILAGE--VVYPP--FFHPDVVDLLGKLITADLTRRLGNLQSGP 307
G PF TP++T K++ + + PP P+ DL+ KL RLG ++G
Sbjct: 945 VGQPPFLAQTPLETQMKVINWQTSLHIPPQAKLSPEASDLIIKLCRGP-EDRLG--KNGA 1001
Query: 308 DDIKSHPWFAEVIWEKLVAKDIETPYEPPIAVGVGDSSLFDQYPEEQL 355
D+IK+HP+F + + + + Y P I D+S FD ++L
Sbjct: 1002 DEIKAHPFFKTIDFSSDLRQQ-SASYIPKITHPT-DTSNFDPVDPDKL 1047
>Hs8923754 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 414
Score = 188 bits (477), Expect = 1e-47
Identities = 106/284 (37%), Positives = 166/284 (58%), Gaps = 14/284 (4%)
Query: 62 FQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRMLKLVEHPF 121
FQI+R +G GSFG+V +V+ + YA+K + K + I ++ + E ++++ +EHPF
Sbjct: 23 FQILRAIGKGSFGKVCIVQKRDTKKMYAMKYMNKQKCIERDEVRNVFRELQIMQGLEHPF 82
Query: 122 LIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLALEYLHSHNI 181
L+ +W +FQD ++FMV+D + GG+L L+++ F K Y E+ LALEYL ++I
Sbjct: 83 LVNLWYSFQDEEDMFMVVDLLLGGDLRYHLQQNVHFTEGTVKLYICELALALEYLQRYHI 142
Query: 182 IYRDLKPENILLDRNGHIKITDFGFAKEV--ITVTWTLCGTPDYIAPEVITT-----KPY 234
I+RD+KP+NILLD +GH+ ITDF A V ++ GT Y+APEV Y
Sbjct: 143 IHRDIKPDNILLDEHGHVHITDFNIATVVKGAERASSMAGTKPYMAPEVFQVYMDRGPGY 202
Query: 235 NKSVDWWSLGILIFEMLAGYTPF--YDVTPMKTYEKILAGE-VVYPPFFHPDVVDLLGKL 291
+ VDWWSLGI +E+L G+ P+ + VTP+ + E V Y + +V LL KL
Sbjct: 203 SYPVDWWSLGITAYELLRGWRPYEIHSVTPIDEILNMFKVERVHYSSTWCKGMVALLRKL 262
Query: 292 ITADLTRRLGNLQSGPDDIKSHPWFAEVIWEKLVAKDIETPYEP 335
+T D R+ +L DI+S P+ A++ W+ + K + + P
Sbjct: 263 LTKDPESRVSSLH----DIQSVPYLADMNWDAVFKKALMPGFVP 302
>SPAC821.12 [R] KOG0605 NDR and related serine/threonine kinases
Length = 469
Score = 187 bits (476), Expect = 2e-47
Identities = 110/362 (30%), Positives = 184/362 (50%), Gaps = 59/362 (16%)
Query: 56 KYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRMLK 115
+ +L DF ++ +G G+FG V LV+ + G+ YA+K L K ++ + Q+ H ER +L
Sbjct: 87 RLSLEDFSTIKVIGKGAFGEVRLVQKLDTGKIYAMKSLLKTEMFKRDQLAHVKAERDLLV 146
Query: 116 LVEHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLALEY 175
+ P+++ ++ FQDS L+++M+++ GG+L ++L F V +FY AE LA+
Sbjct: 147 ESDSPWVVSLYYAFQDSLYLYLIMEFLPGGDLMTMLINYDTFSEDVTRFYMAECVLAIAD 206
Query: 176 LHSHNIIYRDLKPENILLDRNGHIKITDFGFAK-----------------------EVIT 212
+H I+RD+KP+NIL+DR+GHIK++DFG + +++
Sbjct: 207 VHRMGYIHRDIKPDNILIDRDGHIKLSDFGLSTGFYKQDQSASYMKPRTGNTVKRGQMVD 266
Query: 213 VTW---------------------TLCGTPDYIAPEVITTKPYNKSVDWWSLGILIFEML 251
W + GTPDYIAPE+ + Y + DWWSLG ++FE L
Sbjct: 267 AIWLTMSSKDKMATWKKNRRVMAYSTVGTPDYIAPEIFLQQGYGQDCDWWSLGAIMFECL 326
Query: 252 AGYTPFYDVTPMKTYEKIL--AGEVVYPPFFHPDVV--DLLGKLITADLTRRLGNLQSGP 307
G+ PF +TY KI+ + +P H + DL+ +L+T D RLG + G
Sbjct: 327 IGWPPFCSENSHETYRKIINWRETLTFPNDIHLSIEARDLMDRLMT-DSEHRLG--RGGA 383
Query: 308 DDIKSHPWFAEVIWEKLVAKDIETPYEPPIAVGVGDSSLF-----DQYPEEQLDYGVQGE 362
+I HP+F + W+ + ++ P+ P + + D+ F +Q PE+ +
Sbjct: 384 IEIMQHPFFTGIDWDHI--RETAAPFIPNLK-SITDTHYFPVDELEQVPEQPVTQQPASV 440
Query: 363 DP 364
DP
Sbjct: 441 DP 442
>At1g30270 [T] KOG0583 Serine/threonine protein kinase
Length = 480
Score = 186 bits (472), Expect = 5e-47
Identities = 106/317 (33%), Positives = 169/317 (52%), Gaps = 23/317 (7%)
Query: 47 PQRSTVSK----GKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMK 102
P RST S G+ + +++ RTLG G+F +V R+V NG AIKV+ K ++++ K
Sbjct: 12 PSRSTPSGSSSGGRTRVGKYELGRTLGEGTFAKVKFARNVENGDNVAIKVIDKEKVLKNK 71
Query: 103 QIEHTNDERRMLKLVEHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVA 162
I E +KL++HP +IRM+ ++ V++++ GGELF + + R A
Sbjct: 72 MIAQIKREISTMKLIKHPNVIRMFEVMASKTKIYFVLEFVTGGELFDKISSNGRLKEDEA 131
Query: 163 KFYAAEVTLALEYLHSHNIIYRDLKPENILLDRNGHIKITDFGFA---KEVITVTWTLCG 219
+ Y ++ A++Y HS + +RDLKPEN+LLD NG +K++DFG + ++ + T CG
Sbjct: 132 RKYFQQLINAVDYCHSRGVYHRDLKPENLLLDANGALKVSDFGLSALPQQEDGLLHTTCG 191
Query: 220 TPDYIAPEVITTKPYN-KSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPP 278
TP+Y+APEVI K Y+ D WS G+++F ++AGY PF D Y+KI E PP
Sbjct: 192 TPNYVAPEVINNKGYDGAKADLWSCGVILFVLMAGYLPFEDSNLTSLYKKIFKAEFTCPP 251
Query: 279 FFHPDVVDLLGKLITADLTRRLGNLQSGPDDIKSHPWFAEVIWEKLVAKDIETPYEPPIA 338
+F L+ +++ + R+ FAEVI + K + P
Sbjct: 252 WFSASAKKLIKRILDPNPATRI--------------TFAEVIENEWFKKGYKAPKFENAD 297
Query: 339 VGVGD-SSLFDQYPEEQ 354
V + D ++FD E +
Sbjct: 298 VSLDDVDAIFDDSGESK 314
>7291742_1 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1539
Score = 185 bits (470), Expect = 8e-47
Identities = 109/315 (34%), Positives = 171/315 (53%), Gaps = 24/315 (7%)
Query: 52 VSKGKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDER 111
V K + + DF I++ +G G+FG V +V+ + + YA+K+L K ++++ + +ER
Sbjct: 90 VRKLRLSRDDFDILKIIGRGAFGEVCVVQMISTEKVYAMKILNKWEMLKRAETACFREER 149
Query: 112 RMLKLVEHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRK-SQRFPNPVAKFYAAEVT 170
+L + ++ + FQD+ NL++VMDY GG+L +LL K + P +AKFY E+
Sbjct: 150 DVLVFGDRQWITNLHYAFQDNINLYLVMDYYCGGDLLTLLSKFEDKLPEDMAKFYITEMI 209
Query: 171 LALEYLHSHNIIYRDLKPENILLDRNGHIKITDFG----FAKEVITVTWTLCGTPDYIAP 226
LA+ +H ++RD+KP+N+LLD+ GH+++ DFG K+ + GTPDYI+P
Sbjct: 210 LAINSIHQIRYVHRDIKPDNVLLDKRGHVRLADFGSCLRLDKDGTVQSNVAVGTPDYISP 269
Query: 227 EVITTKP-----YNKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKI--------LAGE 273
E++ Y DWWSLG+ ++EML G TPFY + ++TY KI L +
Sbjct: 270 EILRAMEDGKGRYGTECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHQNCFNLPSQ 329
Query: 274 VVYPPFFHPDVVDLLGKLITADLTRRLGNLQSGPDDIKSHPWFAEVIWEKLVAKDIETPY 333
DLL KLI RLG Q+G D HPWF + W+ + + PY
Sbjct: 330 ETLNYKVSETSQDLLCKLICIP-ENRLG--QNGIQDFMDHPWFVGIDWKNI--RQGPAPY 384
Query: 334 EPPIAVGVGDSSLFD 348
P ++ D+S FD
Sbjct: 385 VPEVS-SPTDTSNFD 398
>CE24761 [D] KOG0580 Serine/threonine protein kinase
Length = 305
Score = 185 bits (469), Expect = 1e-46
Identities = 101/287 (35%), Positives = 157/287 (54%), Gaps = 10/287 (3%)
Query: 46 LPQRSTVSK----GKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRM 101
LP++ TV+ GK+T++DF+I R LG G FG V+L R+ + AIKVL K Q+I
Sbjct: 10 LPEKETVNTPQKGGKFTINDFEIGRPLGKGKFGSVYLARTKTGHFHVAIKVLFKSQLISG 69
Query: 102 KQIEHTNDERRMLKLVEHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPV 161
E + + HP +I+++ F D++ +++V++Y GGE++ L S+RF P
Sbjct: 70 GVEHQLEREIEIQSHLNHPNIIKLYTYFWDAKKIYLVLEYAPGGEMYKQLTVSKRFSEPT 129
Query: 162 AKFYAAEVTLALEYLHSHNIIYRDLKPENILLDRNGHIKITDFGFAKEV-ITVTWTLCGT 220
A Y E+ AL Y H N+I+RD+KPEN+L+ G +KI DFG++ T+CGT
Sbjct: 130 AAKYMYEIADALSYCHRKNVIHRDIKPENLLIGSQGELKIGDFGWSVHAPSNKRQTMCGT 189
Query: 221 PDYIAPEVITTKPYNKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFF 280
DY+ PE++ ++ +VD W++G+L +E L G PF KTY I A YP
Sbjct: 190 MDYLPPEMVNGADHSDAVDLWAIGVLCYEFLVGKPPFEHEDQSKTYAAIKAARFTYPDSV 249
Query: 281 HPDVVDLLGKLITADLTRRLGNLQSGPDDIKSHPWFAEVIWEKLVAK 327
DL+G+L+ D R + +K H W ++ K+ A+
Sbjct: 250 KKGARDLIGRLLVVDPKAR-----CTLEQVKEHYWIQGMMEAKIRAE 291
>CE13844 [D] KOG0608 Warts/lats-like serine threonine kinases
Length = 908
Score = 184 bits (466), Expect = 2e-46
Identities = 114/367 (31%), Positives = 188/367 (51%), Gaps = 57/367 (15%)
Query: 38 LAQQKESLLPQRSTVSKGKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQ 97
L QQKES + + + + K + F ++ +G G+FG+V LVR + YA+K L+K
Sbjct: 481 LLQQKES---KYTRLRRQKMSKSHFTVISHIGVGAFGKVSLVRKNDTRKVYAMKSLEKAD 537
Query: 98 IIRMKQIEHTNDERRMLKLVEHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRF 157
+I +Q H ER +L + P+++R++ +FQD L+ +M+Y+ GG++ +LL + F
Sbjct: 538 VIMKQQAAHVKAERDILAEADSPWIVRLFFSFQDDACLYFIMEYVPGGDMMTLLIQKGIF 597
Query: 158 PNPVAKFYAAEVTLALEYLHSHNIIYRDLKPENILLDRNGHIKITDFGFA---------- 207
+A+FY AE+ A+EY+H+ I+RDLKP+NIL+D++GHIK+TDFG
Sbjct: 598 EEDLARFYIAELACAIEYVHNVGFIHRDLKPDNILIDQHGHIKLTDFGLCTGLRWTHDRR 657
Query: 208 -----------------KEVITV-----------------TWTLCGTPDYIAPEVITTKP 233
EV + +L GT +Y+APEVI
Sbjct: 658 YYGPENDHHRVDSFSLPPEVAAIDKSVKVLNVRQQTRRITAHSLVGTGNYMAPEVIAKTG 717
Query: 234 YNKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAG----EVVYPPFFHPDVVDLLG 289
+N+S DWWS G++++EM+ G PF+D TP T +I + Y + + ++
Sbjct: 718 HNQSCDWWSTGVILYEMVFGRVPFHDDTPGGTQHRIKNWRNFLDFTYCGNLSKECLMMIQ 777
Query: 290 KLITADLTRRLG----NLQSGPDDIKSHPWFAEVIWEKLVAKDIETPYEPPIAVGVGDSS 345
+LI D + RLG ++ +K+HPWF + W L + Y P + D+S
Sbjct: 778 QLI-CDASSRLGSHGKDVAERTAQVKNHPWFRGIDWVNLRKLRADYIYIPRVTHD-EDTS 835
Query: 346 LFDQYPE 352
F+ + +
Sbjct: 836 NFETFQD 842
>At2g45490 [D] KOG0580 Serine/threonine protein kinase
Length = 288
Score = 183 bits (464), Expect = 4e-46
Identities = 96/277 (34%), Positives = 159/277 (56%), Gaps = 7/277 (2%)
Query: 56 KYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRMLK 115
+++L DF+I R LG G FGRV+L R + A+KV+ K QI + K E +
Sbjct: 16 QWSLADFEIGRPLGKGKFGRVYLAREAKSKYIVALKVIFKEQIEKYKIHHQLRREMEIQT 75
Query: 116 LVEHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLALEY 175
+ HP ++R++G F D+ +F++++Y GGEL+ +L+++ A Y A ++ AL Y
Sbjct: 76 SLRHPNILRLFGWFHDNERIFLILEYAHGGELYGVLKQNGHLTEQQAATYIASLSQALAY 135
Query: 176 LHSHNIIYRDLKPENILLDRNGHIKITDFGFAKEVITVTWTLCGTPDYIAPEVITTKPYN 235
H +I+RD+KPEN+LLD G +KI DFG++ + T+CGT DY+APE++ + ++
Sbjct: 136 CHGKCVIHRDIKPENLLLDHEGRLKIADFGWSVQSSNKRKTMCGTLDYLAPEMVENRDHD 195
Query: 236 KSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYP--PFFHPDVVDLLGKLIT 293
+VD W+LGIL +E L G PF + T+++IL ++ +P P + +L+ +L+
Sbjct: 196 YAVDNWTLGILCYEFLYGNPPFEAESQKDTFKRILKIDLSFPLTPNVSEEAKNLISQLLV 255
Query: 294 ADLTRRLGNLQSGPDDIKSHPWFAEVIWEKLVAKDIE 330
D ++RL + I HPW + K V I+
Sbjct: 256 KDPSKRL-----SIEKIMQHPWIVKNADPKGVCASID 287
>7301980 [D] KOG0608 Warts/lats-like serine threonine kinases
Length = 1105
Score = 181 bits (459), Expect = 2e-45
Identities = 118/369 (31%), Positives = 190/369 (50%), Gaps = 61/369 (16%)
Query: 38 LAQQKESLLPQRSTVSKGKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRY-YAIKVLKKH 96
+ QKES + + K F ++ +G G+FG V LV + + YA+K L+K
Sbjct: 698 MLNQKES---NYIRLKRAKMDKSMFVKLKPIGVGAFGEVTLVSKIDTSNHLYAMKTLRKA 754
Query: 97 QIIRMKQIEHTNDERRMLKLVEHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQR 156
+++ Q+ H ER +L ++ ++++++ +FQD NL+ VMDYI GG+L SLL K
Sbjct: 755 DVLKRNQVAHVKAERDILAEADNNWVVKLYYSFQDKDNLYFVMDYIPGGDLMSLLIKLGI 814
Query: 157 FPNPVAKFYAAEVTLALEYLHSHNIIYRDLKPENILLDRNGHIKITDFGF---------- 206
F +A+FY AEVT A++ +H I+RD+KP+NIL+DR+GHIK+TDFG
Sbjct: 815 FEEELARFYIAEVTCAVDSVHKMGFIHRDIKPDNILIDRDGHIKLTDFGLCTGFRWTHNS 874
Query: 207 ---------AKEVITVTW---------------------------TLCGTPDYIAPEVIT 230
+++ W +L GTP+YIAPEV+
Sbjct: 875 KYYQENGNHSRQDSMEPWEEYSENGPKPTVLERRRMRDHQRVLAHSLVGTPNYIAPEVLE 934
Query: 231 TKPYNKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGE--VVYPP--FFHPDVVD 286
Y + D+WS+G++++EML G PF +P++T +K++ E + PP + D
Sbjct: 935 RSGYTQLCDYWSVGVILYEMLVGQPPFLANSPLETQQKVINWEKTLHIPPQAELSREATD 994
Query: 287 LLGKLITADLTRRLGNLQSGPDDIKSHPWFAEVIWEKLVAKDIETPYEPPIAVGVGDSSL 346
L+ +L A +RLG D++KSH +F + + + + + PY P I D+S
Sbjct: 995 LIRRL-CASADKRLG---KSVDEVKSHDFFKGIDFADM--RKQKAPYIPEIKHPT-DTSN 1047
Query: 347 FDQYPEEQL 355
FD E+L
Sbjct: 1048 FDPVDPEKL 1056
>YPL209c [D] KOG0580 Serine/threonine protein kinase
Length = 367
Score = 180 bits (457), Expect = 3e-45
Identities = 96/269 (35%), Positives = 156/269 (57%), Gaps = 9/269 (3%)
Query: 58 TLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRMLKLV 117
+L DF++ + LG G FG+V+ VR G A+KV++K +II+ + E + +
Sbjct: 100 SLDDFELGKKLGKGKFGKVYCVRHRSTGYICALKVMEKEEIIKYNLQKQFRREVEIQTSL 159
Query: 118 EHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLALEYLH 177
HP L + +G F D + ++++M+Y+ GE++ LLR F + +A Y ++ AL+Y+H
Sbjct: 160 NHPNLTKSYGYFHDEKRVYLLMEYLVNGEMYKLLRLHGPFNDILASDYIYQIANALDYMH 219
Query: 178 SHNIIYRDLKPENILLDRNGHIKITDFGFA--KEVITVTWTLCGTPDYIAPEVITTKPYN 235
NII+RD+KPENIL+ N IK+TDFG++ T+CGT DY++PE++ ++ Y+
Sbjct: 220 KKNIIHRDIKPENILIGFNNVIKLTDFGWSIINPPENRRKTVCGTIDYLSPEMVESREYD 279
Query: 236 KSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFFHPDVVDLLGKLITAD 295
++D W+LG+L FE+L G PF + TY++I A ++ P D DL+ KL+ D
Sbjct: 280 HTIDAWALGVLAFELLTGAPPFEEEMKDTTYKRIAALDIKMPSNISQDAQDLILKLLKYD 339
Query: 296 LTRRLGNLQSGPDDIKSHPWFA--EVIWE 322
R+ D+K HPW + WE
Sbjct: 340 PKDRM-----RLGDVKMHPWILRNKPFWE 363
>At2g25090 [T] KOG0583 Serine/threonine protein kinase
Length = 469
Score = 180 bits (457), Expect = 3e-45
Identities = 96/292 (32%), Positives = 162/292 (54%), Gaps = 22/292 (7%)
Query: 62 FQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMK-QIEHTNDERRMLKLVEHP 120
+ I R LGTG+F +V+ + G AIKV+KK + + + +E E +++L+ HP
Sbjct: 15 YNIGRLLGTGNFAKVYHGTEISTGDDVAIKVIKKDHVFKRRGMMEQIEREIAVMRLLRHP 74
Query: 121 FLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLALEYLHSHN 180
++ + + +F VM+Y+ GGELF ++ + + P +A+ Y ++ A+++ HS
Sbjct: 75 NVVELREVMATKKKIFFVMEYVNGGELFEMIDRDGKLPEDLARKYFQQLISAVDFCHSRG 134
Query: 181 IIYRDLKPENILLDRNGHIKITDFGFAKEVI------------TVTWTLCGTPDYIAPEV 228
+ +RD+KPEN+LLD G +K+TDFG + ++ + T CGTP Y+APEV
Sbjct: 135 VFHRDIKPENLLLDGEGDLKVTDFGLSALMMPEGLGGRRGSSDDLLHTRCGTPAYVAPEV 194
Query: 229 ITTKPYNKSV-DWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFFHPDVVDL 287
+ K Y+ ++ D WS GI+++ +LAG+ PF D M Y KI E +PP+F + +L
Sbjct: 195 LRNKGYDGAMADIWSCGIVLYALLAGFLPFIDENVMTLYTKIFKAECEFPPWFSLESKEL 254
Query: 288 LGKLITADLTRRLGNLQSGPDDIKSHPWFAEVIWEKL---VAKDIETPYEPP 336
L +L+ D +R+ +IK PWF + + + + I +P EPP
Sbjct: 255 LSRLLVPDPEQRI-----SMSEIKMIPWFRKNFTPSVAFSIDETIPSPPEPP 301
>At5g25110 [T] KOG0583 Serine/threonine protein kinase
Length = 460
Score = 180 bits (456), Expect = 3e-45
Identities = 95/265 (35%), Positives = 158/265 (58%), Gaps = 12/265 (4%)
Query: 62 FQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRMLKLVEHPF 121
+++ R LG G+FG+V+ + + G AIK++ K Q+ R +E E +++LV HP
Sbjct: 15 YEMGRLLGKGTFGKVYYGKEITTGESVAIKIINKDQVKREGMMEQIKREISIMRLVRHPN 74
Query: 122 LIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLALEYLHSHNI 181
++ + +F +M+Y++GGELFS + K + A+ Y ++ A+++ HS +
Sbjct: 75 IVELKEVMATKTKIFFIMEYVKGGELFSKIVKG-KLKEDSARKYFQQLISAVDFCHSRGV 133
Query: 182 IYRDLKPENILLDRNGHIKITDFGFA---KEVIT--VTWTLCGTPDYIAPEVITTKPYNK 236
+RDLKPEN+L+D NG +K++DFG + ++++ + T CGTP Y+APEV+ K Y+
Sbjct: 134 SHRDLKPENLLVDENGDLKVSDFGLSALPEQILQDGLLHTQCGTPAYVAPEVLRKKGYDG 193
Query: 237 SV-DWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFFHPDVVDLLGKLITAD 295
+ D WS GI+++ +LAG+ PF D MK Y KI E YPP+F P+ L+ KL+ D
Sbjct: 194 AKGDIWSCGIILYVLLAGFLPFQDENLMKMYRKIFKSEFEYPPWFSPESKRLISKLLVVD 253
Query: 296 LTRRLGNLQSGPDDIKSHPWFAEVI 320
+R+ S P +++ PWF + I
Sbjct: 254 PNKRI----SIPAIMRT-PWFRKNI 273
>CE08098 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1173
Score = 179 bits (455), Expect = 4e-45
Identities = 102/289 (35%), Positives = 160/289 (55%), Gaps = 16/289 (5%)
Query: 61 DFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRMLKLVEHP 120
DF+ ++ +G G+FG VHLVR YA+K+L K +I+ +ER ++
Sbjct: 67 DFRQLKVIGRGAFGEVHLVRHTRTNTVYAMKMLNKDDMIKRADSAFFWEERDIMAHANSE 126
Query: 121 FLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLALEYLHSHN 180
+++R+ FQD R+L+MVM+Y+ GG+L +L+ S +FY AE+ AL LHS
Sbjct: 127 WIVRLQYAFQDPRHLYMVMEYMPGGDLVNLM-TSYEVSEKWTRFYTAEIVEALAALHSMG 185
Query: 181 IIYRDLKPENILLDRNGHIKITDFGFAKEV----ITVTWTLCGTPDYIAPEVITTK---- 232
I+RD+KP+N+L+ +GHIK+ DFG ++ + T GTPDYI+PEV+ +
Sbjct: 186 YIHRDVKPDNMLISISGHIKLADFGTCVKMNANGVVRCSTAVGTPDYISPEVLRNQGQDA 245
Query: 233 PYNKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKIL--AGEVVYP--PFFHPDVVDLL 288
+ K VDWWS+G+ I+EML G TPFY + TY I+ + +P P D++
Sbjct: 246 EFGKEVDWWSVGVFIYEMLVGETPFYAEALVSTYTNIMNHKTSLKFPDEPLISTQAKDII 305
Query: 289 GKLITADLTRRLGNLQSGPDDIKSHPWFAEVIWEKLVAKDIETPYEPPI 337
K ++A RLG ++ DDI++H +F W ++ P P +
Sbjct: 306 KKFLSA-APDRLG--RNSVDDIRNHKFFVNDEWTFATLREASPPVIPSL 351
>SPBC4C3.11 [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 420
Score = 179 bits (454), Expect = 6e-45
Identities = 107/314 (34%), Positives = 166/314 (52%), Gaps = 27/314 (8%)
Query: 35 DYLLAQ-QKESLLPQRSTVSKGKYTLH--------DFQIMRTLGTGSFGRVHLVRSVHNG 85
DY A+ ++ + PQ S V G T H D+ +G GSF +V +
Sbjct: 20 DYFEARGERNPVKPQSSNVVPG--TSHIGSIKSPADYVFGDIIGDGSFSKVRRATDKKSW 77
Query: 86 RYYAIKVLKKHQIIRMKQIEHTNDER-RMLKLVEHPFLIRMWGTFQDSRNLFMVMDYIEG 144
+ YAIKVL K I++ ++++ N ER M++L P + R++ TFQD L+ V++
Sbjct: 78 KEYAIKVLDKKYIVKENKVKYVNIERDSMMRLNGFPGISRLFHTFQDDLKLYYVLELAPN 137
Query: 145 GELFSLLRKSQRFPNPVAKFYAAEVTLALEYLHSHNIIYRDLKPENILLDRNGHIKITDF 204
GEL ++K + +FYAAE+ ++EY+HS II+RDLKPENIL D N H+KITDF
Sbjct: 138 GELLQYIKKYRFLDENCVRFYAAEILSSIEYMHSCGIIHRDLKPENILFDGNMHVKITDF 197
Query: 205 GFAK----------EVITVTWTLCGTPDYIAPEVITTKPYNKSVDWWSLGILIFEMLAGY 254
G AK + T + GT +Y+APE+++ + +KS D W+ ++++M+ G
Sbjct: 198 GTAKILPPKYVNSPDYTTFPSSFVGTAEYVAPELLSRQVVSKSSDLWAFACVVYQMIVGS 257
Query: 255 TPFYDVTPMKTYEKILAGEVVYPPFFHPDVVDLLGKLITADLTRRLGNLQSGPDDIKSHP 314
PF+ P ++KI++ E P PD+V L L + R S IK P
Sbjct: 258 PPFHGSNPNNIFKKIMSLEYELPKLLPPDIVPLFSHLFRIQPSDR-----STTQQIKQFP 312
Query: 315 WFAEVIWEKLVAKD 328
+FA + W+ L +D
Sbjct: 313 FFATITWDNLWTQD 326
>7293249 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1390
Score = 179 bits (454), Expect = 6e-45
Identities = 101/303 (33%), Positives = 169/303 (55%), Gaps = 14/303 (4%)
Query: 47 PQRSTVSKGKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEH 106
P +++ + + DF ++ +G G+FG V LVR + + YA+K L K ++++
Sbjct: 72 PLAMQINQLRMNVEDFHFIKLIGAGAFGEVQLVRHKSSSQVYAMKRLSKFEMMKRPDSAF 131
Query: 107 TNDERRMLKLVEHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYA 166
+ER ++ +++++ FQD++ L+MVMD++ GG++ SL+ P A FY
Sbjct: 132 FWEERHIMAHANSEWIVQLHFAFQDAKYLYMVMDFMPGGDIVSLM-GDYDIPEKWAIFYT 190
Query: 167 AEVTLALEYLHSHNIIYRDLKPENILLDRNGHIKITDFGFAKEV----ITVTWTLCGTPD 222
EV LAL+ +H+ ++RD+KP+N+LLD GH+K+ DFG + V+ GTPD
Sbjct: 191 MEVVLALDTIHNMGFVHRDVKPDNMLLDSYGHLKLADFGTCMRMGANGQVVSSNAVGTPD 250
Query: 223 YIAPEVITTK----PYNKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKIL--AGEVVY 276
YI+PEV+ ++ Y + DWWS+GI ++EML G TPFY + + TY KI+ + +
Sbjct: 251 YISPEVLQSQGVDNEYGRECDWWSVGIFLYEMLFGETPFYADSLVGTYGKIMDHKNSLSF 310
Query: 277 PPFFH-PDVVDLLGKLITADLTRRLGNLQSGPDDIKSHPWFAEVIWEKLVAKDIETPYEP 335
PP + L + D T+RLG + G +DIK+HP+F W ++ P P
Sbjct: 311 PPEVEISEQAKALIRAFLTDRTQRLG--RYGIEDIKAHPFFRNDTWSFDNIRESVPPVVP 368
Query: 336 PIA 338
++
Sbjct: 369 ELS 371
>At1g29230 [T] KOG0583 Serine/threonine protein kinase
Length = 520
Score = 178 bits (452), Expect = 1e-44
Identities = 97/281 (34%), Positives = 158/281 (55%), Gaps = 15/281 (5%)
Query: 29 VGSQSTDY---LLAQQKESLLPQRSTVSKGKYTLHDFQIMRTLGTGSFGRVHLVRSVHNG 85
+G TD + Q S R+ + GKY L + LG G+F +V+L +++ +G
Sbjct: 43 IGIMDTDKDGNISPQSPRSPRSPRNNILMGKYELG-----KLLGHGTFAKVYLAQNIKSG 97
Query: 86 RYYAIKVLKKHQIIRMKQIEHTNDERRMLKLVEHPFLIRMWGTFQDSRNLFMVMDYIEGG 145
AIKV+ K +I++ + H E +L+ V HP+++ ++ ++ VM+Y+ GG
Sbjct: 98 DKVAIKVIDKEKIMKSGLVAHIKREISILRRVRHPYIVHLFEVMATKSKIYFVMEYVGGG 157
Query: 146 ELFSLLRKSQRFPNPVAKFYAAEVTLALEYLHSHNIIYRDLKPENILLDRNGHIKITDFG 205
ELF+ + K R P A+ Y ++ ++ + H + +RDLKPEN+LLD G++K++DFG
Sbjct: 158 ELFNTVAKG-RLPEETARRYFQQLISSVSFCHGRGVYHRDLKPENLLLDNKGNLKVSDFG 216
Query: 206 FAKEVIT-----VTWTLCGTPDYIAPEVITTKPYNKS-VDWWSLGILIFEMLAGYTPFYD 259
+ + T CGTP YIAPEV+T K Y+ + D WS G+++F ++AG+ PFYD
Sbjct: 217 LSAVAEQLRQDGLCHTFCGTPAYIAPEVLTRKGYDAAKADVWSCGVILFVLMAGHIPFYD 276
Query: 260 VTPMKTYEKILAGEVVYPPFFHPDVVDLLGKLITADLTRRL 300
M Y+KI GE P +F D+V LL +L+ + R+
Sbjct: 277 KNIMVMYKKIYKGEFRCPRWFSSDLVRLLTRLLDTNPDTRI 317
>YOL100w [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 1081
Score = 177 bits (448), Expect = 3e-44
Identities = 100/303 (33%), Positives = 169/303 (55%), Gaps = 29/303 (9%)
Query: 42 KESLLPQRSTVSKGKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRM 101
KES Q++ + KG + DF+ +G G++ V L S+ + YA KVL K +IR
Sbjct: 162 KESSKAQKNIIKKG---IKDFKFGSVIGDGAYSTVMLATSIDTKKRYAAKVLNKEYLIRQ 218
Query: 102 KQIEHTNDERRML-KLVEHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNP 160
K++++ + E+ L KL P ++R++ TFQD +L+ +++Y G+ SL++K
Sbjct: 219 KKVKYVSIEKTALQKLNNSPSVVRLFSTFQDESSLYFLLEYAPNGDFLSLMKKYGSLDET 278
Query: 161 VAKFYAAEVTLALEYLHSHNIIYRDLKPENILLDRNGHIKITDFGFAK------------ 208
A++YAA++ A++YLHS+ II+RD+KPENILLD IK+TDFG AK
Sbjct: 279 CARYYAAQIIDAIDYLHSNGIIHRDIKPENILLDGEMKIKLTDFGTAKLLNPTNNSVSKP 338
Query: 209 --EVITVTWTLCGTPDYIAPEVITTKPYNKSVDWWSLGILIFEMLAGYTPFYDVTPMKTY 266
++ T + + GT +Y++PE++ + D W+ G ++F+M+AG PF T+
Sbjct: 339 EYDLSTRSKSFVGTAEYVSPELLNDSFTDYRCDIWAFGCILFQMIAGKPPFKATNEYLTF 398
Query: 267 EKILAGEVVYPPFFHPDVVDLLGKLITADLTRRLGNLQSGPDDIKSHPWFAEV------I 320
+K++ + + P F + DL+ K++ +L RRL Q IK H +F ++ +
Sbjct: 399 QKVMKVQYAFTPGFPLIIRDLVKKILVKNLDRRLTISQ-----IKEHHFFKDLNFKDGSV 453
Query: 321 WEK 323
W K
Sbjct: 454 WSK 456
>SPCC320.12c [D] KOG0580 Serine/threonine protein kinase
Length = 384
Score = 177 bits (448), Expect = 3e-44
Identities = 90/259 (34%), Positives = 151/259 (57%), Gaps = 7/259 (2%)
Query: 62 FQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRMLKLVEHPF 121
F+I + LG G FGRV+L + G A+K L K ++++ K + E + + H
Sbjct: 118 FEIGKPLGKGKFGRVYLAKEKKTGFIVALKTLHKSELVQSKIEKQVRREIEIQSNLRHKN 177
Query: 122 LIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLALEYLHSHNI 181
++R++G F D + +++++++ GEL+ LR+++RF VA Y ++ AL YLH ++
Sbjct: 178 ILRLYGHFHDEKRIYLILEFAGRGELYQHLRRAKRFSEEVASKYIFQMANALSYLHKKHV 237
Query: 182 IYRDLKPENILLDRNGHIKITDFGFAKEV-ITVTWTLCGTPDYIAPEVITTKPYNKSVDW 240
I+RD+KPENILL +G IK++DFG++ TLCGT DY+ PE++ K + + VD
Sbjct: 238 IHRDIKPENILLGIDGEIKLSDFGWSVHAPSNRRTTLCGTLDYLPPEMVEGKEHTEKVDL 297
Query: 241 WSLGILIFEMLAGYTPFYDVT-PMKTYEKILAGEVVYPPFFHPDVVDLLGKLITADLTRR 299
WSLG+L +E L G PF D++ TY++I ++ P F PD DL+ +L+ + +R
Sbjct: 298 WSLGVLTYEFLVGAPPFEDMSGHSATYKRIAKVDLKIPSFVPPDARDLISRLLQHNPEKR 357
Query: 300 LGNLQSGPDDIKSHPWFAE 318
+ + + HPW +
Sbjct: 358 M-----SLEQVMRHPWIVK 371
>At4g18700 [T] KOG0583 Serine/threonine protein kinase
Length = 489
Score = 176 bits (445), Expect = 6e-44
Identities = 93/264 (35%), Positives = 155/264 (58%), Gaps = 8/264 (3%)
Query: 42 KESLLPQRSTVSKGKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRM 101
+E+ LP+ + S L +++ + LG G+F +V+L R+V AIKV+ K ++++
Sbjct: 7 RETSLPKERS-SPQALILGRYEMGKLLGHGTFAKVYLARNVKTNESVAIKVIDKEKVLKG 65
Query: 102 KQIEHTNDERRMLKLVEHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPV 161
I H E +L+ V HP +++++ ++ VM+Y+ GGELF+ + K R V
Sbjct: 66 GLIAHIKREISILRRVRHPNIVQLFEVMATKAKIYFVMEYVRGGELFNKVAKG-RLKEEV 124
Query: 162 AKFYAAEVTLALEYLHSHNIIYRDLKPENILLDRNGHIKITDFGFAKEVITVT-----WT 216
A+ Y ++ A+ + H+ + +RDLKPEN+LLD NG++K++DFG + + T
Sbjct: 125 ARKYFQQLISAVTFCHARGVYHRDLKPENLLLDENGNLKVSDFGLSAVSDQIRQDGLFHT 184
Query: 217 LCGTPDYIAPEVITTKPYNKS-VDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVV 275
CGTP Y+APEV+ K Y+ + VD WS G+++F ++AGY PF+D M Y+KI GE
Sbjct: 185 FCGTPAYVAPEVLARKGYDAAKVDIWSCGVILFVLMAGYLPFHDRNVMAMYKKIYRGEFR 244
Query: 276 YPPFFHPDVVDLLGKLITADLTRR 299
P +F ++ LL KL+ + +R
Sbjct: 245 CPRWFSTELTRLLSKLLETNPEKR 268
>At5g45820 [T] KOG0583 Serine/threonine protein kinase
Length = 439
Score = 175 bits (444), Expect = 8e-44
Identities = 96/287 (33%), Positives = 160/287 (55%), Gaps = 18/287 (6%)
Query: 55 GKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRML 114
G + +++ R LG G+F +V+ R++ G AIKV+ K ++ ++ I+ E ++
Sbjct: 5 GIVLMRKYELGRLLGQGTFAKVYHARNIKTGESVAIKVIDKQKVAKVGLIDQIKREISVM 64
Query: 115 KLVEHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLALE 174
+LV HP ++ + ++ M+Y++GGELF + K + N +A+ Y ++ A++
Sbjct: 65 RLVRHPHVVFLHEVMASKTKIYFAMEYVKGGELFDKVSKGKLKEN-IARKYFQQLIGAID 123
Query: 175 YLHSHNIIYRDLKPENILLDRNGHIKITDFGF-----AKEVITVTWTLCGTPDYIAPEVI 229
Y HS + +RDLKPEN+LLD NG +KI+DFG +K+ + T CGTP Y+APEVI
Sbjct: 124 YCHSRGVYHRDLKPENLLLDENGDLKISDFGLSALRESKQQDGLLHTTCGTPAYVAPEVI 183
Query: 230 TTKPYN-KSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFFHPDVVDLL 288
K Y+ D WS G++++ +LAG+ PF++ ++ Y KI GE P +F P+V LL
Sbjct: 184 GKKGYDGAKADVWSCGVVLYVLLAGFLPFHEQNLVEMYRKITKGEFKCPNWFPPEVKKLL 243
Query: 289 GKLITADLTRRLGNLQSGPDDIKSHPWFAEVIWEKLVAKDIETPYEP 335
+++ + R+ + I + WF + K IETP P
Sbjct: 244 SRILDPNPNSRI-----KIEKIMENSWFQKGF------KKIETPKSP 279
>At4g32830 [D] KOG0580 Serine/threonine protein kinase
Length = 294
Score = 174 bits (442), Expect = 1e-43
Identities = 95/282 (33%), Positives = 156/282 (54%), Gaps = 10/282 (3%)
Query: 40 QQKESLLPQRSTVSKGKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQII 99
Q+KE+ + K ++TL DF I + LG G FG V+L R + A+KVL K Q+
Sbjct: 10 QEKEASDASAAAAQK-RWTLSDFDIGKPLGRGKFGHVYLAREKRSNHVVALKVLFKSQL- 67
Query: 100 RMKQIEHT-NDERRMLKLVEHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFP 158
+ Q+EH E + + HP ++R++G F D + ++++++Y GEL+ L+K + F
Sbjct: 68 QQSQVEHQLRREVEIQSHLRHPNILRLYGYFYDQKRVYLILEYAARGELYKDLQKCKYFS 127
Query: 159 NPVAKFYAAEVTLALEYLHSHNIIYRDLKPENILLDRNGHIKITDFGFAKEVITVTWTLC 218
A Y A + AL Y H ++I+RD+KPEN+L+ G +KI DFG++ T+C
Sbjct: 128 ERRAATYVASLARALIYCHGKHVIHRDIKPENLLIGAQGELKIADFGWSVHTFNRRRTMC 187
Query: 219 GTPDYIAPEVITTKPYNKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYP- 277
GT DY+ PE++ + ++ SVD WSLGIL +E L G PF + TY +I+ ++ +P
Sbjct: 188 GTLDYLPPEMVESVEHDASVDIWSLGILCYEFLYGVPPFEAMEHSDTYRRIVQVDLKFPP 247
Query: 278 -PFFHPDVVDLLGKLITADLTRRLGNLQSGPDDIKSHPWFAE 318
P DL+ +++ + ++RL + HPW +
Sbjct: 248 KPIISASAKDLISQMLVKESSQRL-----PLHKLLEHPWIVQ 284
>7299536 [D] KOG0580 Serine/threonine protein kinase
Length = 411
Score = 174 bits (442), Expect = 1e-43
Identities = 102/290 (35%), Positives = 154/290 (52%), Gaps = 11/290 (3%)
Query: 29 VGSQSTDYLLAQQKESLLPQRSTVSKGKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYY 88
+G+ S+ + K PQ+ K + L++F I R LG G FG V+L R +
Sbjct: 124 LGAASSSAEKEKTKTETQPQKP---KKTWELNNFDIGRLLGRGKFGNVYLAREKESQFVV 180
Query: 89 AIKVLKKHQIIRMKQIEHTNDERRMLKLVEHPFLIRMWGTFQDSRNLFMVMDYIEGGELF 148
A+KVL K QI E + + HP ++R++ F D ++++++Y G LF
Sbjct: 181 ALKVLFKRQIGESNVEHQVRREIEIQSHLRHPHILRLYAYFHDDVRIYLILEYAPQGTLF 240
Query: 149 SLLRKS--QRFPNPVAKFYAAEVTLALEYLHSHNIIYRDLKPENILLDRNGHIKITDFGF 206
+ L+ +RF + Y + AL YLH +II+RD+KPEN+LL G +KI DFG+
Sbjct: 241 NALQAQPMKRFDERQSATYIQALCSALLYLHERDIIHRDIKPENLLLGHKGVLKIADFGW 300
Query: 207 A-KEVITVTWTLCGTPDYIAPEVITTKPYNKSVDWWSLGILIFEMLAGYTPFYDVTPMKT 265
+ E ++ TLCGT DY+ PE++ KP+ K+VD WSLG+L FE+L G+ PFY +T
Sbjct: 301 SVHEPNSMRMTLCGTVDYLPPEMVQGKPHTKNVDLWSLGVLCFELLVGHAPFYSKNYDET 360
Query: 266 YEKILAGEVVYPPFFHPDVVDLLGKLITADLTRRLGNLQSGPDDIKSHPW 315
Y+KIL + P L+ KL+ + RL D + HPW
Sbjct: 361 YKKILKVDYKLPEHISKAASHLISKLLVLNPQHRL-----PLDQVMVHPW 405
>Hs10334852 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 623
Score = 174 bits (441), Expect = 2e-43
Identities = 102/305 (33%), Positives = 170/305 (55%), Gaps = 23/305 (7%)
Query: 61 DFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRMLKLVEHP 120
DF+I++ +G G+F V +V+ G+ YA+K++ K +++ ++ +ER +L +
Sbjct: 70 DFEILKVIGRGAFSEVAVVKMKQTGQVYAMKIMNKWDMLKRGEVSCFREERDVLVNGDRR 129
Query: 121 FLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRK-SQRFPNPVAKFYAAEVTLALEYLHSH 179
++ ++ FQD L++VM+Y GG+L +LL K +R P +A+FY AE+ +A++ +H
Sbjct: 130 WITQLHFAFQDENYLYLVMEYYVGGDLLTLLSKFGERIPAEMARFYLAEIVMAIDSVHRL 189
Query: 180 NIIYRDLKPENILLDRNGHIKITDFGFAKEV----ITVTWTLCGTPDYIAPEVIT----- 230
++RD+KP+NILLDR GHI++ DFG ++ + GTPDY++PE++
Sbjct: 190 GYVHRDIKPDNILLDRCGHIRLADFGSCLKLRADGTVRSLVAVGTPDYLSPEILQAVGGG 249
Query: 231 --TKPYNKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKIL-AGEVVYPPFFHPDVV-- 285
T Y DWW+LG+ +EM G TPFY + +TY KI+ E + P V
Sbjct: 250 PGTGSYGPECDWWALGVFAYEMFYGQTPFYADSTAETYGKIVHYKEHLSLPLVDEGVPEE 309
Query: 286 --DLLGKLITADLTRRLGNLQSGPDDIKSHPWFAEVIWEKLVAKDIETPYEPPIAVGVGD 343
D + +L+ T RLG + G D ++HP+F + W+ L +D P+ P G D
Sbjct: 310 ARDFIQRLLCPPET-RLG--RGGAGDFRTHPFFFGLDWDGL--RDSVPPFTPDFE-GATD 363
Query: 344 SSLFD 348
+ FD
Sbjct: 364 TCNFD 368
>YBR028c [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 525
Score = 174 bits (440), Expect = 2e-43
Identities = 101/333 (30%), Positives = 170/333 (50%), Gaps = 57/333 (17%)
Query: 59 LHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQII------------------- 99
LHDF+ +R LG G++G+V LV+ V+ + YA+K L+K +I+
Sbjct: 125 LHDFKPVRVLGQGAYGKVLLVKDVNTSKLYAMKQLRKAEILISQTATDSKREDEDKNDGN 184
Query: 100 -------RMKQIEHTNDERRMLKLVEHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLR 152
K++E T ER +L +EHP +++++ +F D+ L++++ YI GGELF L+
Sbjct: 185 NNDNDDGLSKRLERTFAERSILSEIEHPNIVKLFYSFHDNSKLYLLLQYIPGGELFYHLK 244
Query: 153 KSQRFPNPVAKFYAAEVTLALEYLHSHNIIYRDLKPENILLDRNGHIKITDFGFAK---- 208
+ FYAAE++ AL +LH+ ++YRDLKPEN LL++ GH+ +TDFG +K
Sbjct: 245 EHGTLDETTVSFYAAEISCALRFLHTKGVVYRDLKPENCLLNQRGHLVLTDFGLSKKSAN 304
Query: 209 ---------EVITVTWTLCGTPDYIAPEVITTKPYNKSVDWWSLGILIFEMLAGYTPFYD 259
E + +++ GTP+Y APE++ K Y+++ DW+SLG L+++ML G P+
Sbjct: 305 DSAVDEEDPENVNALYSIIGTPEYCAPEILLGKAYSQNCDWYSLGCLLYDMLVGKPPYTG 364
Query: 260 VTPMKTYEKILAGE--VVYPPFFHPDVVDLLGKLITADLTRRLGNLQSGPDDIKSHPWFA 317
KI + P + + D+L L+ + +R W
Sbjct: 365 SNHKVIINKIQQNKQGPKIPFYLSEGMKDILNALLKKETAKR---------------WNV 409
Query: 318 EVIWEKLVAKDIETPYEPPIAVGVGDSSLFDQY 350
+ W K A + T + + G +SLF ++
Sbjct: 410 DKYWAKTGANNKPTKSKKKKS-GAARTSLFTEH 441
>Hs4501971 [T] KOG0986 G protein-coupled receptor kinase
Length = 689
Score = 174 bits (440), Expect = 2e-43
Identities = 110/306 (35%), Positives = 164/306 (52%), Gaps = 11/306 (3%)
Query: 58 TLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTN-DERRMLKL 116
T++DF + R +G G FG V+ R G+ YA+K L K +I +MKQ E +ER ML L
Sbjct: 187 TMNDFSVHRIIGRGGFGEVYGCRKRDTGKMYAMKCLDKKRI-KMKQGETLALNERIMLSL 245
Query: 117 V---EHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLAL 173
V + PF++ M F L ++D + GG+L L + F +FYAAE+ L L
Sbjct: 246 VSTGDCPFIVCMSYAFHTPDKLSFILDLMNGGDLHYHLSQHGVFSEADMRFYAAEIILGL 305
Query: 174 EYLHSHNIIYRDLKPENILLDRNGHIKITDFGFAKEVI-TVTWTLCGTPDYIAPEVITT- 231
E++H+ ++YRDLKP NILLD +GH++I+D G A + GT Y+APEV+
Sbjct: 306 EHMHNRFVVYRDLKPANILLDEHGHVRISDLGLACDFSKKKPHASVGTHGYMAPEVLQKG 365
Query: 232 KPYNKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYE---KILAGEVVYPPFFHPDVVDLL 288
Y+ S DW+SLG ++F++L G++PF +E L V P F P++ LL
Sbjct: 366 VAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHEIDRMTLTMAVELPDSFSPELHSLL 425
Query: 289 GKLITADLTRRLGNLQSGPDDIKSHPWFAEVIWEKLVAKDIETPYEPPIA-VGVGDSSLF 347
L+ D+ RRLG L G ++K P+F + W+ + + P PP V D+
Sbjct: 426 EGLLQRDVNRRLGCLGRGAQEVKESPFFRSLDWQMVFLQRYPPPLIPPRGEVNAADAFDI 485
Query: 348 DQYPEE 353
+ EE
Sbjct: 486 GSFDEE 491
>CE03492 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 379
Score = 174 bits (440), Expect = 2e-43
Identities = 94/288 (32%), Positives = 151/288 (51%), Gaps = 14/288 (4%)
Query: 50 STVSKGKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTND 109
S K L F ++R++G G+FG+V +V+ +Y+A+K + K + I +
Sbjct: 16 SVSGKSAPCLQHFSVIRSIGRGAFGKVCIVQERKTKKYFALKYMNKRRCIEKGVAANVIR 75
Query: 110 ERRMLKLVEHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEV 169
E +L + HPF++ +W TFQD ++MV D + GG+L L + +F AK Y E+
Sbjct: 76 ELTLLSKMSHPFIVNLWYTFQDGDYMYMVSDLLLGGDLRYHLSQQGKFAEDRAKLYLCEI 135
Query: 170 TLALEYLHSHNIIYRDLKPENILLDRNGHIKITDFGFAKEV--ITVTWTLCGTPDYIAPE 227
LA+EYLH I++RD+KPENILLD GH +TD A ++ + + GT Y+APE
Sbjct: 136 CLAVEYLHEMKIVHRDIKPENILLDEQGHAHLTDLNLATQLEDDQLATSYSGTRPYMAPE 195
Query: 228 VITT-----KPYNKSVDWWSLGILIFEMLAGYTPF---YDVTPMKTYEKILAGEVVYPPF 279
+ T Y+ VDWW+LG+ +EML G TPF P + Y + YP
Sbjct: 196 IYATYLEIEDGYDSRVDWWALGVCFYEMLRGRTPFEFSSRTKPEEAYVAFRESSIPYPAH 255
Query: 280 FHPDVVDLLGKLITADLTRRLGNLQSGPDDIKSHPWFAEVIWEKLVAK 327
+ D++ + ++ D +RL L++ IK H + + ++ + K
Sbjct: 256 WPTDLIQFINSMLKFDKEKRLVGLEA----IKKHSYTERIDFKSVFEK 299
>CE21025 [D] KOG0580 Serine/threonine protein kinase
Length = 326
Score = 173 bits (439), Expect = 3e-43
Identities = 103/315 (32%), Positives = 171/315 (53%), Gaps = 21/315 (6%)
Query: 30 GSQSTDYLLAQQKESLL-------PQRSTVSKGK--YTLHDFQIMRTLGTGSFGRVHLVR 80
G ++T ++ QK ++ PQR ++ + ++L DF + R LG G FG V + R
Sbjct: 3 GKENTAPVIDDQKAEVISLTEDSRPQRVDQAREESCWSLDDFDVGRPLGKGKFGNVFISR 62
Query: 81 SVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRMLKLVEHPFLIRMWGTFQDSRNLFMVMD 140
R A+KVL K Q++++ E + + HP ++ ++G F D + +F+++D
Sbjct: 63 EKKTKRIIALKVLFKTQLLQLGVSHQLKREIEIQYHLRHPNILTLYGYFHDDKRVFVILD 122
Query: 141 YIEGGELFSLLRKS--QRFPNPVAKFYAAEVTLALEYLHSHNIIYRDLKPENILLDRNGH 198
Y GELF++L+ + +A + ++ AL Y HS +I+RD+KPEN+LLD +
Sbjct: 123 YASRGELFNVLQSQPGHKVNEVIAGRFVRQLANALHYCHSKGVIHRDIKPENLLLDSKLN 182
Query: 199 IKITDFGFAKEVI-TVTWTLCGTPDYIAPEVITTKPYNKSVDWWSLGILIFEMLAGYTPF 257
+K+ DFG++ + TLCGT DY+APE+++ +P++ +VD W++GIL+FEML GY PF
Sbjct: 183 LKLADFGWSVVADHSKRHTLCGTMDYLAPEMVSNQPHDFNVDIWAIGILLFEMLVGYAPF 242
Query: 258 YDVTPMKTYEKILAGEVVYPPFFHPDVVDLLGKLITADLTRRLGNLQSGPDDIKSHPWFA 317
+ T K +I ++ P L+ +I + RL + DI +HPW
Sbjct: 243 ANQTGDKLIARIKECKIYIPSVVTDGAASLINAIIKKEPQERLPLV-----DIMAHPW-- 295
Query: 318 EVIWEKLVAKDIETP 332
I E +DIE P
Sbjct: 296 --IKEMKQREDIEVP 308
>At2g26980 [T] KOG0583 Serine/threonine protein kinase
Length = 441
Score = 173 bits (439), Expect = 3e-43
Identities = 91/293 (31%), Positives = 159/293 (54%), Gaps = 24/293 (8%)
Query: 62 FQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRMLKLVEHPF 121
+++ RT+G G+F +V R+ G A+K+L K ++++ K E E +KL++HP
Sbjct: 14 YEVGRTIGEGTFAKVKFARNSETGEPVALKILDKEKVLKHKMAEQIRREIATMKLIKHPN 73
Query: 122 LIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLALEYLHSHNI 181
+++++ +F++++Y+ GGELF + R A+ Y ++ A++Y HS +
Sbjct: 74 VVQLYEVMASKTKIFIILEYVTGGELFDKIVNDGRMKEDEARRYFQQLIHAVDYCHSRGV 133
Query: 182 IYRDLKPENILLDRNGHIKITDFGFAKEVITV-----TWTLCGTPDYIAPEVITTKPYN- 235
+RDLKPEN+LLD G++KI+DFG + V T CGTP+Y+APEV+ + Y+
Sbjct: 134 YHRDLKPENLLLDSYGNLKISDFGLSALSQQVRDDGLLHTSCGTPNYVAPEVLNDRGYDG 193
Query: 236 KSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFFHPDVVDLLGKLITAD 295
+ D WS G++++ +LAGY PF D M Y+KI +GE PP+ + L+ +++ +
Sbjct: 194 ATADMWSCGVVLYVLLAGYLPFDDSNLMNLYKKISSGEFNCPPWLSLGAMKLITRILDPN 253
Query: 296 LTRRLGNLQSGPDDIKSHPWFAEVIWEKLVAKDIETPYEPPIAVGVGDSSLFD 348
R+ P ++ WF + Y+PP+ DS++ D
Sbjct: 254 PMTRV-----TPQEVFEDEWF-------------KKDYKPPVFEERDDSNMDD 288
>CE02074 [T] KOG0986 G protein-coupled receptor kinase
Length = 727
Score = 173 bits (438), Expect = 4e-43
Identities = 111/327 (33%), Positives = 176/327 (52%), Gaps = 14/327 (4%)
Query: 58 TLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTN-DERRMLKL 116
T++DF + R +G G FG V+ R G+ YA+K L K +I +MKQ E +ER ML L
Sbjct: 187 TMNDFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRI-KMKQGETLALNERIMLSL 245
Query: 117 V----EHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLA 172
V + PF++ M FQ L ++D + GG+L L + F FYA+EV L
Sbjct: 246 VSTGQDCPFIVCMTYAFQSPDKLCFILDLMNGGDLHYHLSQHGVFTEQEMIFYASEVILG 305
Query: 173 LEYLHSHNIIYRDLKPENILLDRNGHIKITDFGFAKEVI-TVTWTLCGTPDYIAPEVITT 231
LE++H+ ++YRDLKP NILLD NGH++++D G A + GT Y+APEV+
Sbjct: 306 LEHMHNRFVVYRDLKPANILLDENGHVRVSDLGLACDYSKKKPHASVGTHGYMAPEVLAK 365
Query: 232 -KPYNKSVDWWSLGILIFEMLAGYTPF--YDVTPMKTYEKILAGEVVYPP--FFHPDVVD 286
Y+ S DW+SLG +++++L G++PF + +K+ + + P D D
Sbjct: 366 GVAYDSSADWFSLGCMLYKLLKGHSPFRQHKSKDKNEIDKMTLTQDIELPNEGLSKDCRD 425
Query: 287 LLGKLITADLTRRLGNLQSGPDDIKSHPWFAEVIWEKLVAKDIETPYEPPIA-VGVGDSS 345
LL L+ D+ RLG GP ++K HP+F +V W+ + + + P PP V D+
Sbjct: 426 LLEGLLKRDVPDRLGCRGKGPTEVKEHPFFKDVDWQTVYLRRMTPPLIPPRGEVNAADAF 485
Query: 346 LFDQYPEEQLDYGVQGEDPYGQYFLDF 372
+ ++++ GV+ +D + +F
Sbjct: 486 DIGNFDDDEVK-GVKLQDGDSDLYKNF 511
>At2g25880 [D] KOG0580 Serine/threonine protein kinase
Length = 282
Score = 173 bits (438), Expect = 4e-43
Identities = 92/272 (33%), Positives = 152/272 (55%), Gaps = 9/272 (3%)
Query: 50 STVSKGKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHT-N 108
S ++ ++T DF I + LG G FG V+L R + A+KVL K Q+ + Q+EH
Sbjct: 7 SEAAQKRWTTSDFDIGKPLGRGKFGHVYLAREKRSDHIVALKVLFKAQL-QQSQVEHQLR 65
Query: 109 DERRMLKLVEHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAE 168
E + + HP ++R++G F D + ++++++Y GEL+ L+K + F A Y A
Sbjct: 66 REVEIQSHLRHPNILRLYGYFYDQKRVYLILEYAVRGELYKELQKCKYFSERRAATYVAS 125
Query: 169 VTLALEYLHSHNIIYRDLKPENILLDRNGHIKITDFGFAKEVITVTWTLCGTPDYIAPEV 228
+ AL Y H ++I+RD+KPEN+L+ G +KI DFG++ T+CGT DY+ PE+
Sbjct: 126 LARALIYCHGKHVIHRDIKPENLLIGAQGELKIADFGWSVHTFNRRRTMCGTLDYLPPEM 185
Query: 229 ITTKPYNKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYP--PFFHPDVVD 286
+ + ++ SVD WSLGIL +E L G PF +TY++I+ ++ +P P D
Sbjct: 186 VESVEHDASVDIWSLGILCYEFLYGVPPFEAREHSETYKRIVQVDLKFPPKPIVSSSAKD 245
Query: 287 LLGKLITADLTRRLGNLQSGPDDIKSHPWFAE 318
L+ +++ + T+RL + HPW +
Sbjct: 246 LISQMLVKESTQRL-----ALHKLLEHPWIVQ 272
>At1g53700 [R] KOG0610 Putative serine/threonine protein kinase
Length = 476
Score = 173 bits (438), Expect = 4e-43
Identities = 114/339 (33%), Positives = 167/339 (48%), Gaps = 63/339 (18%)
Query: 53 SKGKYTLHDFQIMRTLGTGSFGRVHL--VRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDE 110
S G+ L F+++R LGTG+ GRV L +R N +A+KV+ + ++ K+I H E
Sbjct: 84 SDGRLHLRHFKLVRHLGTGNLGRVFLCHLRDCPNPTGFALKVIDR-DVLTAKKISHVETE 142
Query: 111 RRMLKLVEHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRK--SQRFPNPVAKFYAAE 168
+L L++HPFL ++ S +++DY G+L SLLRK + R P +F+AAE
Sbjct: 143 AEILSLLDHPFLPTLYARIDASHYTCLLIDYCPNGDLHSLLRKQPNNRLPISPVRFFAAE 202
Query: 169 VTLALEYLHSHNIIYRDLKPENILLDRNGHIKITDFG----------------------- 205
V +ALEYLH+ I+YRDLKPENIL+ +GHI ++DF
Sbjct: 203 VLVALEYLHALGIVYRDLKPENILIREDGHIMLSDFDLCFKADVVPTFRSRRFRRTSSSP 262
Query: 206 ------------------------FAKEVITVTWTLC-GTPDYIAPEVITTKPYNKSVDW 240
FA E +T C GT +Y+APE++ + VDW
Sbjct: 263 RKTRRGGGCFSTEVEYEREEIVAEFAAEPVTAFSKSCVGTHEYLAPELVAGNGHGSGVDW 322
Query: 241 WSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFFHPDVV---DLLGKLITADLT 297
W+ GI ++EML G TPF T +T I++ + V +V DL+ KL+ D
Sbjct: 323 WAFGIFLYEMLYGTTPFKGGTKEQTLRNIVSNDDVAFTLEEEGMVEAKDLIEKLLVKDPR 382
Query: 298 RRLGNLQSGPDDIKSHPWFAEVIWEKLVAKDIETPYEPP 336
+RLG G DIK H +F + W + Y+PP
Sbjct: 383 KRLG-CARGAQDIKRHEFFEGIKWPLI------RNYKPP 414
>At5g35410 [T] KOG0583 Serine/threonine protein kinase
Length = 446
Score = 171 bits (434), Expect = 1e-42
Identities = 86/259 (33%), Positives = 152/259 (58%), Gaps = 9/259 (3%)
Query: 62 FQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRMLKLVEHPF 121
+++ RT+G G+F +V R+ G AIK++ K I++ + ++ E ++K+V HP
Sbjct: 11 YEVGRTIGEGTFAKVKFARNTDTGDNVAIKIMAKSTILKNRMVDQIKREISIMKIVRHPN 70
Query: 122 LIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLALEYLHSHNI 181
++R++ +++V++++ GGELF + R ++ Y ++ A+ + H +
Sbjct: 71 IVRLYEVLASPSKIYIVLEFVTGGELFDRIVHKGRLEESESRKYFQQLVDAVAHCHCKGV 130
Query: 182 IYRDLKPENILLDRNGHIKITDFGFA---KEVITVTWTLCGTPDYIAPEVITTKPYNKS- 237
+RDLKPEN+LLD NG++K++DFG + +E + + T CGTP+Y+APEV++ + Y+ S
Sbjct: 131 YHRDLKPENLLLDTNGNLKVSDFGLSALPQEGVELLRTTCGTPNYVAPEVLSGQGYDGSA 190
Query: 238 VDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFFHPDVVDLLGKLITADLT 297
D WS G+++F +LAGY PF + Y KI A E PP+F +V L+ +++ +
Sbjct: 191 ADIWSCGVILFVILAGYLPFSETDLPGLYRKINAAEFSCPPWFSAEVKFLIHRILDPNPK 250
Query: 298 RRLGNLQSGPDDIKSHPWF 316
R+ +Q IK PWF
Sbjct: 251 TRI-QIQG----IKKDPWF 264
>At2g34180 [T] KOG0583 Serine/threonine protein kinase
Length = 502
Score = 171 bits (434), Expect = 1e-42
Identities = 89/278 (32%), Positives = 155/278 (55%), Gaps = 16/278 (5%)
Query: 47 PQRSTVSKGKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEH 106
P+ +G + ++I + LG GSF +V+L R++H+G AIKV+ K +I++ H
Sbjct: 42 PRSPRTPQGSILMDKYEIGKLLGHGSFAKVYLARNIHSGEDVAIKVIDKEKIVKSGLAGH 101
Query: 107 TNDERRMLKLVEHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYA 166
E +L+ V HP+++ + +++VM+Y+ GGEL++ + + R A+ Y
Sbjct: 102 IKREISILRRVRHPYIVHLLEVMATKTKIYIVMEYVRGGELYNTVARG-RLREGTARRYF 160
Query: 167 AEVTLALEYLHSHNIIYRDLKPENILLDRNGHIKITDFGFAKEVIT-------VTWTLCG 219
++ ++ + HS + +RDLK EN+LLD G++K++DFG + V++ + T CG
Sbjct: 161 QQLISSVAFCHSRGVYHRDLKLENLLLDDKGNVKVSDFGLS--VVSEQLKQEGICQTFCG 218
Query: 220 TPDYIAPEVITTKPY-NKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPP 278
TP Y+APEV+T K Y D WS G+++F ++AGY PF D + Y KI G+ P
Sbjct: 219 TPAYLAPEVLTRKGYEGAKADIWSCGVILFVLMAGYLPFDDKNILVMYTKIYKGQFKCPK 278
Query: 279 FFHPDVVDLLGKLITADLTRRLGNLQSGPDDIKSHPWF 316
+F P++ L+ +++ + R+ +I H WF
Sbjct: 279 WFSPELARLVTRMLDTNPDTRI-----TIPEIMKHRWF 311
>At4g24400 [T] KOG0583 Serine/threonine protein kinase
Length = 445
Score = 171 bits (433), Expect = 2e-42
Identities = 85/281 (30%), Positives = 161/281 (57%), Gaps = 6/281 (2%)
Query: 62 FQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRMLKLVEHPF 121
+++ RT+G G+F +V ++ G A+K++ + II+ K ++ E ++KLV HP
Sbjct: 9 YELGRTIGEGTFAKVKFAQNTETGESVAMKIVDRSTIIKRKMVDQIKREISIMKLVRHPC 68
Query: 122 LIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLALEYLHSHNI 181
++R++ ++++++YI GGELF + ++ R A+ Y ++ ++Y HS +
Sbjct: 69 VVRLYEVLASRTKIYIILEYITGGELFDKIVRNGRLSESEARKYFHQLIDGVDYCHSKGV 128
Query: 182 IYRDLKPENILLDRNGHIKITDFGFA---KEVITVTWTLCGTPDYIAPEVITTKPYNKSV 238
+RDLKPEN+LLD G++KI+DFG + ++ +T+ T CGTP+Y+APEV++ K YN +V
Sbjct: 129 YHRDLKPENLLLDSQGNLKISDFGLSALPEQGVTILKTTCGTPNYVAPEVLSHKGYNGAV 188
Query: 239 -DWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFFHPDVVDLLGKLITADLT 297
D WS G++++ ++AGY PF ++ Y KI E P +F L+ +++ +
Sbjct: 189 ADIWSCGVILYVLMAGYLPFDEMDLPTLYSKIDKAEFSCPSYFALGAKSLINRILDPNPE 248
Query: 298 RRLGNLQSGPDD--IKSHPWFAEVIWEKLVAKDIETPYEPP 336
R+ + D+ +K + + +E + D+ ++ P
Sbjct: 249 TRITIAEIRKDEWFLKDYTPVQLIDYEHVNLDDVYAAFDDP 289
>At5g45810 [T] KOG0583 Serine/threonine protein kinase
Length = 483
Score = 170 bits (431), Expect = 3e-42
Identities = 92/285 (32%), Positives = 159/285 (55%), Gaps = 12/285 (4%)
Query: 38 LAQQKESLLPQRSTVSKGKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQ 97
L ++ +S+ ++ + L +++ R LG G+F +V+L R+ +G AIKV+ K +
Sbjct: 4 LLRKVKSIKKKQDQSNHQALILGKYEMGRLLGHGTFAKVYLARNAQSGESVAIKVIDKEK 63
Query: 98 IIRMKQIEHTNDERRMLKLVEHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRF 157
+++ I H E +L+ V HP +++++ ++ VM+Y++GGELF+ + K R
Sbjct: 64 VLKSGLIAHIKREISILRRVRHPNIVQLFEVMATKSKIYFVMEYVKGGELFNKVAKG-RL 122
Query: 158 PNPVAKFYAAEVTLALEYLHSHNIIYRDLKPENILLDRNGHIKITDFGFAKEVITVT--- 214
+A+ Y ++ A+ + H + +RDLKPEN+LLD NG++K++DFG + +
Sbjct: 123 KEEMARKYFQQLISAVSFCHFRGVYHRDLKPENLLLDENGNLKVSDFGLSAVSDQIRQDG 182
Query: 215 --WTLCGTPDYIAPEVITTKPYN-KSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILA 271
T CGTP Y+APEV+ K Y+ VD WS G+++F ++AG+ PF+D M Y+KI
Sbjct: 183 LFHTFCGTPAYVAPEVLARKGYDGAKVDIWSCGVILFVLMAGFLPFHDRNVMAMYKKIYR 242
Query: 272 GEVVYPPFFHPDVVDLLGKLITADLTRRLGNLQSGPDDIKSHPWF 316
G+ P +F ++ LL +++ RR DI WF
Sbjct: 243 GDFRCPRWFPVEINRLLIRMLETKPERRF-----TMPDIMETSWF 282
>Hs4885055 [T] KOG0986 G protein-coupled receptor kinase
Length = 688
Score = 170 bits (430), Expect = 4e-42
Identities = 107/306 (34%), Positives = 162/306 (51%), Gaps = 11/306 (3%)
Query: 58 TLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTN-DERRMLKL 116
T+++F + R +G G FG V+ R G+ YA+K L K +I +MKQ E +ER ML L
Sbjct: 187 TMNEFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRI-KMKQGETLALNERIMLSL 245
Query: 117 V---EHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLAL 173
V + PF++ M F L ++D + GG+L L + F +FYA E+ L L
Sbjct: 246 VSTGDCPFIVCMTYAFHTPDKLCFILDLMNGGDLHYHLSQHGVFSEKEMRFYATEIILGL 305
Query: 174 EYLHSHNIIYRDLKPENILLDRNGHIKITDFGFAKEVI-TVTWTLCGTPDYIAPEVITT- 231
E++H+ ++YRDLKP NILLD +GH +I+D G A + GT Y+APEV+
Sbjct: 306 EHVHNRFVVYRDLKPANILLDEHGHARISDLGLACDFSKKKPHASVGTHGYMAPEVLQKG 365
Query: 232 KPYNKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYE---KILAGEVVYPPFFHPDVVDLL 288
Y+ S DW+SLG ++F++L G++PF +E L V P F P++ LL
Sbjct: 366 TAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHEIDRMTLTVNVELPDTFSPELKSLL 425
Query: 289 GKLITADLTRRLGNLQSGPDDIKSHPWFAEVIWEKLVAKDIETPYEPPIA-VGVGDSSLF 347
L+ D+++RLG G ++K H +F V W+ + + P PP V D+
Sbjct: 426 EGLLQRDVSKRLGCHGGGSQEVKEHSFFKGVDWQHVYLQKYPPPLIPPRGEVNAADAFDI 485
Query: 348 DQYPEE 353
+ EE
Sbjct: 486 GSFDEE 491
>At5g10930 [T] KOG0583 Serine/threonine protein kinase
Length = 445
Score = 170 bits (430), Expect = 4e-42
Identities = 89/246 (36%), Positives = 145/246 (58%), Gaps = 8/246 (3%)
Query: 62 FQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQII-RMKQIEHTNDERRMLKLVEHP 120
+++ R LG G+F +V+ + + G AIKV+ K Q++ R +E E ++KLV HP
Sbjct: 12 YEMGRLLGKGTFAKVYYGKEIIGGECVAIKVINKDQVMKRPGMMEQIKREISIMKLVRHP 71
Query: 121 FLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLALEYLHSHN 180
++ + +F VM++++GGELF + K + A+ Y ++ A++Y HS
Sbjct: 72 NIVELKEVMATKTKIFFVMEFVKGGELFCKISKG-KLHEDAARRYFQQLISAVDYCHSRG 130
Query: 181 IIYRDLKPENILLDRNGHIKITDFGFA---KEVIT--VTWTLCGTPDYIAPEVITTKPYN 235
+ +RDLKPEN+LLD NG +KI+DFG + ++++ + T CGTP Y+APEV+ K Y+
Sbjct: 131 VSHRDLKPENLLLDENGDLKISDFGLSALPEQILQDGLLHTQCGTPAYVAPEVLKKKGYD 190
Query: 236 KS-VDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFFHPDVVDLLGKLITA 294
+ D WS G++++ +LAG PF D M Y KI + +PP+F P+ L+ KL+
Sbjct: 191 GAKADIWSCGVVLYVLLAGCLPFQDENLMNMYRKIFRADFEFPPWFSPEARRLISKLLVV 250
Query: 295 DLTRRL 300
D RR+
Sbjct: 251 DPDRRI 256
>At3g01090 [T] KOG0583 Serine/threonine protein kinase
Length = 512
Score = 169 bits (429), Expect = 5e-42
Identities = 89/261 (34%), Positives = 146/261 (55%), Gaps = 8/261 (3%)
Query: 59 LHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRMLKLVE 118
L ++++ RTLG GSFGRV + G AIK+L + +I M+ E E ++L+L
Sbjct: 16 LPNYKLGRTLGIGSFGRVKIAEHALTGHKVAIKILNRRKIKNMEMEEKVRREIKILRLFM 75
Query: 119 HPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLALEYLHS 178
HP +IR++ + ++++VM+Y+ GELF + + R A+ + ++ +EY H
Sbjct: 76 HPHIIRLYEVIETPTDIYLVMEYVNSGELFDYIVEKGRLQEDEARNFFQQIISGVEYCHR 135
Query: 179 HNIIYRDLKPENILLDRNGHIKITDFGFAKEVITVTW--TLCGTPDYIAPEVITTKPY-N 235
+ +++RDLKPEN+LLD ++KI DFG + + + T CG+P+Y APEVI+ K Y
Sbjct: 136 NMVVHRDLKPENLLLDSKCNVKIADFGLSNIMRDGHFLKTSCGSPNYAAPEVISGKLYAG 195
Query: 236 KSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFFHPDVVDLLGKLITAD 295
VD WS G++++ +L G PF D ++KI G P P DL+ +++ D
Sbjct: 196 PEVDVWSCGVILYALLCGTLPFDDENIPNLFKKIKGGIYTLPSHLSPGARDLIPRMLVVD 255
Query: 296 LTRRLGNLQSGPDDIKSHPWF 316
+R+ +I+ HPWF
Sbjct: 256 PMKRV-----TIPEIRQHPWF 271
>ECU01g1320 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 865
Score = 169 bits (428), Expect = 6e-42
Identities = 110/326 (33%), Positives = 175/326 (52%), Gaps = 34/326 (10%)
Query: 52 VSKGKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDER 111
V + K D++I++ + G +G V LVR + YA+K + K +++ E+
Sbjct: 35 VVEAKTKPSDYEIVKNVAKGGYGEVFLVR---REKIYAMKRVSKELVLKQPHTALFMAEK 91
Query: 112 R-MLKLVEHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVT 170
M+ + +L+ T QD L+ +MD+I GG+ LL K +FYAAE+
Sbjct: 92 EAMVDCIGSEWLVCAHMTMQDEEYLYYLMDFIPGGDFMGLLSKEDVLEEDWVRFYAAEIV 151
Query: 171 LALEYLHSHNIIYRDLKPENILLDRNGHIKITDFGF--------AKEVITVTWTLCGTPD 222
AL+ LH I+RDLKP+N+L+ +GH+K+ DFG A+ ITV GTPD
Sbjct: 152 AALDELHKLGWIHRDLKPDNVLIGIDGHVKLADFGSCIKMKDGKARSSITV-----GTPD 206
Query: 223 YIAPEVITTK----PYNKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPP 278
Y++P+V+ + Y + VD+W+LG++I+EM+ G TPFY T M+TY +I E +P
Sbjct: 207 YVSPDVLCSVNEECEYGEDVDFWTLGVIIYEMIYGTTPFYSDTLMETYRRITRVEFGFPF 266
Query: 279 FFHPDVVDLLGKLITA-DLTRRLGNLQSGPDDIKSHPWFAEVIWEKLVAKDIETPYEPPI 337
P++ L+ LI A D R+ ++IKSH +F V W +L K+++ P+ P +
Sbjct: 267 KVSPELTSLIEGLIAAKDRRMRI-------EEIKSHAFFEGVDWSRL--KELKPPFVPEV 317
Query: 338 AVGVGDSSLF--DQYPEEQLDYGVQG 361
G D+S F Q+ E+ V+G
Sbjct: 318 N-GDSDTSHFVDTQFDAEKRKLNVKG 342
>At3g14370 [R] KOG0610 Putative serine/threonine protein kinase
Length = 480
Score = 169 bits (428), Expect = 6e-42
Identities = 108/341 (31%), Positives = 163/341 (47%), Gaps = 66/341 (19%)
Query: 53 SKGKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERR 112
S G L +++R LGTG+ GRV L + +A+KV+ ++ + K++ E
Sbjct: 79 SDGNIHLRHLKLIRHLGTGNLGRVFLCNLRDSSARFALKVIDRNCLTTEKKLSQVETEAE 138
Query: 113 MLKLVEHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRK--SQRFPNPVAKFYAAEVT 170
+L L++HPFL ++ +S +++DY G+L SLLRK R P +F+AAEV
Sbjct: 139 ILSLLDHPFLPTLYARIDESHYTCLLIDYAPNGDLHSLLRKQPGNRLPIQPVRFFAAEVL 198
Query: 171 LALEYLHSHNIIYRDLKPENILLDRNGHIKITDFG------------------------- 205
+ALEYLH+ I+YRDLKPEN+LL +GH+ ++DF
Sbjct: 199 VALEYLHAMGIVYRDLKPENVLLREDGHVMLSDFDLCFKSDVVPTFKSRRYRRSSSSPSL 258
Query: 206 ------------------------FAKEVITVTWTLC-GTPDYIAPEVITTKPYNKSVDW 240
FA E +T C GT +Y+APE+++ + VDW
Sbjct: 259 RRRRSGCFSVAAEKKYEREEIVSEFAAEPVTAFSRSCVGTHEYLAPELVSGNGHGSGVDW 318
Query: 241 WSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFFHPD-----VVDLLGKLITAD 295
W+ GI ++E+L G TPF + +T I++ FH D DL+ KL+ D
Sbjct: 319 WAFGIFLYELLYGTTPFKGESKEQTLRNIVS--TTKTASFHMDGDLDEARDLIEKLLVKD 376
Query: 296 LTRRLGNLQSGPDDIKSHPWFAEVIWEKLVAKDIETPYEPP 336
+RLG G DIK HP+F + W + Y+PP
Sbjct: 377 PRKRLG-CARGAQDIKRHPFFDGIKWPLI------RHYKPP 410
>Hs4507273 [D] KOG0580 Serine/threonine protein kinase
Length = 275
Score = 169 bits (427), Expect = 8e-42
Identities = 92/261 (35%), Positives = 143/261 (54%), Gaps = 6/261 (2%)
Query: 56 KYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRMLK 115
+ T+ DF+I R LG G FG V+L R + A+KVL K QI + E +
Sbjct: 3 RLTVDDFEIGRPLGKGKFGNVYLARLKESHFIVALKVLFKSQIEKEGLEHQLRREIEIQA 62
Query: 116 LVEHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLALEY 175
++HP ++R++ F D+R ++++++Y GEL+ L+KS++ EV AL Y
Sbjct: 63 HLQHPNILRLYNYFHDARRVYLILEYAPRGELYKELQKSEKLDEQRTATIIEEVADALTY 122
Query: 176 LHSHNIIYRDLKPENILLDRNGHIKITDFGFAKEV-ITVTWTLCGTPDYIAPEVITTKPY 234
H +I+RD+KPEN+LL G +KI DFG++ + T+CGT DY+ PE+I + Y
Sbjct: 123 CHDKKVIHRDIKPENLLLGFRGEVKIADFGWSVHTPLPERKTMCGTLDYLPPEMIEGRTY 182
Query: 235 NKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFFHPDVVDLLGKLITA 294
++ VD W +G+L +E+L GY PF + +TY +IL +V +P DL+ +L+
Sbjct: 183 DEKVDLWCIGVLCYELLVGYPPFESASHSETYRRILKVDVRFPLSMPLGARDLISRLLRY 242
Query: 295 DLTRRLGNLQSGPDDIKSHPW 315
RL Q I HPW
Sbjct: 243 QPLERLPLAQ-----ILKHPW 258
>At5g39440 [T] KOG0583 Serine/threonine protein kinase
Length = 494
Score = 168 bits (426), Expect = 1e-41
Identities = 92/268 (34%), Positives = 146/268 (54%), Gaps = 7/268 (2%)
Query: 51 TVSKGKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDE 110
T +K L +++I +TLG GSF +V L V G AIK+L + +I M E
Sbjct: 8 TTNKLVSILPNYRIGKTLGHGSFAKVKLALHVATGHKVAIKILNRSKIKNMGIEIKVQRE 67
Query: 111 RRMLKLVEHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVT 170
++L+ + HP +IR + + ++++VM+Y++ GELF + + + A+ ++
Sbjct: 68 IKILRFLMHPHIIRQYEVIETPNDIYVVMEYVKSGELFDYIVEKGKLQEDEARHLFQQII 127
Query: 171 LALEYLHSHNIIYRDLKPENILLDRNGHIKITDFGFAKEVITVTW--TLCGTPDYIAPEV 228
+EY H + I++RDLKPEN+LLD +IKI DFG + + + T CG+P+Y APEV
Sbjct: 128 SGVEYCHRNMIVHRDLKPENVLLDSQCNIKIVDFGLSNVMHDGHFLKTSCGSPNYAAPEV 187
Query: 229 ITTKPYNKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFFHPDVVDLL 288
I+ KPY VD WS G++++ +L G PF D +EKI G P DL+
Sbjct: 188 ISGKPYGPDVDIWSCGVILYALLCGTLPFDDENIPNVFEKIKRGMYTLPNHLSHFARDLI 247
Query: 289 GKLITADLTRRLGNLQSGPDDIKSHPWF 316
+++ D T R+ +I+ HPWF
Sbjct: 248 PRMLMVDPTMRI-----SITEIRQHPWF 270
>7294566 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1252
Score = 167 bits (424), Expect = 2e-41
Identities = 106/309 (34%), Positives = 171/309 (55%), Gaps = 32/309 (10%)
Query: 35 DYLLAQQKESLLPQRSTVSKGKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLK 94
D +A+ P K + DF I +G G FG VHLV YA+K +K
Sbjct: 86 DRNIAEFVNKFRPIIEETRKLRVNADDFLIKTLIGQGYFGNVHLVVERQTNDIYAMKKIK 145
Query: 95 KHQIIRMKQIEHTNDERRMLKLVEHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKS 154
K ++ Q++ +ER ++ + +LI + FQD+ NL++VM+Y+ GG+L SL+ +
Sbjct: 146 K-SVVTTSQVK---EERDIMSIRNSEWLINLQYAFQDNDNLYLVMEYMPGGDLLSLMSRH 201
Query: 155 QRFPNPVAKFYAAEVTLALEYLHSHNIIYRDLKPENILLDRNGHIKITDFGFA----KEV 210
F +A+FY AE+T+AL LH ++RD+KPENIL+DR GHIK+ DFG A ++
Sbjct: 202 GPFDEDLARFYLAELTVALHTLHEMGYVHRDIKPENILIDRFGHIKLADFGNAAALDRDG 261
Query: 211 ITVTWTLCGTPDYIAPEVITT--------KPYNKSVDWWSLGILIFEMLAGYTPFYDVTP 262
++ + GTPDYIAPE++ T ++ S D+WS+GI+ +E++ TPF++
Sbjct: 262 HVLSLSPVGTPDYIAPELLQTISTYKLSKSMHDVSCDYWSMGIIGYELICETTPFHEDNV 321
Query: 263 MKTYEKILA--------GEVVYPPFFHPDV--VDLLGKLITADLTRRLGNLQSGPDDIKS 312
+TY KIL+ + +P V +L+ L+T + ++RL + IK+
Sbjct: 322 HETYSKILSHCEESHLKELISFPADLKVSVNYRNLIESLVT-NPSKRLSY-----ERIKN 375
Query: 313 HPWFAEVIW 321
HP+F+E+ W
Sbjct: 376 HPFFSEIPW 384
>7290150 [T] KOG0583 Serine/threonine protein kinase
Length = 582
Score = 167 bits (424), Expect = 2e-41
Identities = 94/287 (32%), Positives = 154/287 (52%), Gaps = 19/287 (6%)
Query: 67 TLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRMLKLVEHPFLIRMW 126
TLGTG+FG+V + A+K+L + +I + + E + LKL HP +I+++
Sbjct: 33 TLGTGTFGKVKIGEHQITRVKVAVKILNRQKIKSLDVVGKIRREIQNLKLFRHPHIIKLY 92
Query: 127 GTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLALEYLHSHNIIYRDL 186
++FM+M+Y+ GGELF + K + A+ + ++ ++Y H H I++RDL
Sbjct: 93 QVISTPSDIFMIMEYVSGGELFDYIVKHGKLQEHQARRFFQQIISGVDYCHRHMIVHRDL 152
Query: 187 KPENILLDRNGHIKITDFGFAKEVITVTW--TLCGTPDYIAPEVITTKPY-NKSVDWWSL 243
KPEN+LLD N H+KI DFG + ++ + T CG+P+Y APEVI+ K Y VD WS
Sbjct: 153 KPENLLLDHNMHVKIADFGLSNMMLDGEFLRTSCGSPNYAAPEVISGKLYAGPEVDIWSC 212
Query: 244 GILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFFHPDVVDLLGKLITADLTRRLGNL 303
G++++ +L G PF D + KI +G P + + VV+L+ +++ D +R
Sbjct: 213 GVILYALLCGTLPFDDEHVPTLFRKIKSGIFPIPEYLNKQVVNLVCQMLQVDPLKR---- 268
Query: 304 QSGPDDIKSHPWFAEVIWEKLVAKDIETPYEPPIAVGVGDSSLFDQY 350
+ ++IK H WF + + L IE DS++ D Y
Sbjct: 269 -ANIEEIKKHEWFQKDLPAYLFPSSIEQ-----------DSNVIDTY 303
>Hs4759178 [D] KOG0580 Serine/threonine protein kinase
Length = 344
Score = 165 bits (418), Expect = 9e-41
Identities = 92/263 (34%), Positives = 150/263 (56%), Gaps = 12/263 (4%)
Query: 57 YTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRMLKL 116
+T+ DF+I R LG G FG V+L R + A+KVL K QI + + +EH RR +++
Sbjct: 72 FTIDDFEIGRPLGKGKFGNVYLAREKKSHFIVALKVLFKSQIEK-EGVEH--QLRREIEI 128
Query: 117 ---VEHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLAL 173
+ HP ++R++ F D R ++++++Y GEL+ L+KS F E+ AL
Sbjct: 129 QAHLHHPNILRLYNYFYDRRRIYLILEYAPRGELYKELQKSCTFDEQRTATIMEELADAL 188
Query: 174 EYLHSHNIIYRDLKPENILLDRNGHIKITDFGFAKEVITV-TWTLCGTPDYIAPEVITTK 232
Y H +I+RD+KPEN+LL G +KI DFG++ ++ T+CGT DY+ PE+I +
Sbjct: 189 MYCHGKKVIHRDIKPENLLLGLKGELKIADFGWSVHAPSLRRKTMCGTLDYLPPEMIEGR 248
Query: 233 PYNKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFFHPDVVDLLGKLI 292
+N+ VD W +G+L +E+L G PF + +TY +I+ ++ +P DL+ KL+
Sbjct: 249 MHNEKVDLWCIGVLCYELLVGNPPFESASHNETYRRIVKVDLKFPASVPTGAQDLISKLL 308
Query: 293 TADLTRRLGNLQSGPDDIKSHPW 315
+ + RL Q + +HPW
Sbjct: 309 RHNPSERLPLAQ-----VSAHPW 326
>Hs4504101 [T] KOG0986 G protein-coupled receptor kinase
Length = 576
Score = 165 bits (418), Expect = 9e-41
Identities = 109/303 (35%), Positives = 163/303 (52%), Gaps = 11/303 (3%)
Query: 58 TLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRMLKLV 117
T + F+ R LG G FG V + G+ YA K L+K +I + K +E+++L+ V
Sbjct: 182 TKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALNEKQILEKV 241
Query: 118 EHPFLIRMWGTFQDSRNLFMVMDYIEGGEL-FSLLRKSQR-FPNPVAKFYAAEVTLALEY 175
F++ + ++ L +V+ + GG+L F + Q FP A FYAAE+ LE
Sbjct: 242 NSRFVVSLAYAYETKDALCLVLTLMNGGDLKFHIYHMGQAGFPEARAVFYAAEICCGLED 301
Query: 176 LHSHNIIYRDLKPENILLDRNGHIKITDFGFAKEV---ITVTWTLCGTPDYIAPEVITTK 232
LH I+YRDLKPENILLD +GHI+I+D G A V T+ + GT Y+APEV+ +
Sbjct: 302 LHRERIVYRDLKPENILLDDHGHIRISDLGLAVHVPEGQTIKGRV-GTVGYMAPEVVKNE 360
Query: 233 PYNKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKI--LAGEV--VYPPFFHPDVVDLL 288
Y S DWW+LG L++EM+AG +PF E++ L EV Y F P L
Sbjct: 361 RYTFSPDWWALGCLLYEMIAGQSPFQQRKKKIKREEVERLVKEVPEEYSERFSPQARSLC 420
Query: 289 GKLITADLTRRLGNLQSGPDDIKSHPWFAEVIWEKLVAKDIETPYEP-PIAVGVGDSSLF 347
+L+ D RLG ++K HP F ++ +++L A +E P++P P A+ D
Sbjct: 421 SQLLCKDPAERLGCRGGSAREVKEHPLFKKLNFKRLGAGMLEPPFKPDPQAIYCKDVLDI 480
Query: 348 DQY 350
+Q+
Sbjct: 481 EQF 483
>At1g01140 [T] KOG0583 Serine/threonine protein kinase
Length = 447
Score = 165 bits (418), Expect = 9e-41
Identities = 82/259 (31%), Positives = 149/259 (56%), Gaps = 6/259 (2%)
Query: 48 QRSTVSKGKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHT 107
+R + + ++++ RTLG GSF +V ++ G AIK+L + ++ R K +E
Sbjct: 5 RRKATPASRTRVGNYEMGRTLGEGSFAKVKYAKNTVTGDQAAIKILDREKVFRHKMVEQL 64
Query: 108 NDERRMLKLVEHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAA 167
E +KL++HP ++ + +++V++ + GGELF + + R A+ Y
Sbjct: 65 KREISTMKLIKHPNVVEIIEVMASKTKIYIVLELVNGGELFDKIAQQGRLKEDEARRYFQ 124
Query: 168 EVTLALEYLHSHNIIYRDLKPENILLDRNGHIKITDFG---FAKEVIT--VTWTLCGTPD 222
++ A++Y HS + +RDLKPEN++LD NG +K++DFG F+++V + T CGTP+
Sbjct: 125 QLINAVDYCHSRGVYHRDLKPENLILDANGVLKVSDFGLSAFSRQVREDGLLHTACGTPN 184
Query: 223 YIAPEVITTKPYN-KSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFFH 281
Y+APEV++ K Y+ + D WS G+++F ++AGY PF + M Y++I E PP+F
Sbjct: 185 YVAPEVLSDKGYDGAAADVWSCGVILFVLMAGYLPFDEPNLMTLYKRICKAEFSCPPWFS 244
Query: 282 PDVVDLLGKLITADLTRRL 300
++ +++ + R+
Sbjct: 245 QGAKRVIKRILEPNPITRI 263
>Hs4506529 [T] KOG0986 G protein-coupled receptor kinase
Length = 563
Score = 165 bits (417), Expect = 1e-40
Identities = 93/285 (32%), Positives = 156/285 (54%), Gaps = 11/285 (3%)
Query: 62 FQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRMLKLVEHPF 121
F R LG G FG V + G+ YA K L K ++ + K + E+++L V F
Sbjct: 190 FLDFRVLGKGGFGEVSACQMKATGKLYACKKLNKKRLKKRKGYQGAMVEKKILMKVHSRF 249
Query: 122 LIRMWGTFQDSRNLFMVMDYIEGGEL----FSLLRKSQRFPNPVAKFYAAEVTLALEYLH 177
++ + F+ +L +VM + GG++ +++ ++ FP P A FY A++ LE+LH
Sbjct: 250 IVSLAYAFETKADLCLVMTIMNGGDIRYHIYNVNEENPGFPEPRALFYTAQIICGLEHLH 309
Query: 178 SHNIIYRDLKPENILLDRNGHIKITDFGFAKEVI---TVTWTLCGTPDYIAPEVITTKPY 234
I+YRDLKPEN+LLD +G+++I+D G A E++ + T GTP ++APE++ + Y
Sbjct: 310 QRRIVYRDLKPENVLLDNDGNVRISDLGLAVELLDGQSKTKGYAGTPGFMAPELLQGEEY 369
Query: 235 NKSVDWWSLGILIFEMLAGYTPF----YDVTPMKTYEKILAGEVVYPPFFHPDVVDLLGK 290
+ SVD+++LG+ ++EM+A PF V + +I++ V YP F D
Sbjct: 370 DFSVDYFALGVTLYEMIAARGPFRARGEKVENKELKHRIISEPVKYPDKFSQASKDFCEA 429
Query: 291 LITADLTRRLGNLQSGPDDIKSHPWFAEVIWEKLVAKDIETPYEP 335
L+ D +RLG D +++HP F ++ W +L A + P+ P
Sbjct: 430 LLEKDPEKRLGFRDETCDKLRAHPLFKDLNWRQLEAGMLMPPFIP 474
>Hs14196445 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 476
Score = 165 bits (417), Expect = 1e-40
Identities = 91/258 (35%), Positives = 143/258 (55%), Gaps = 8/258 (3%)
Query: 62 FQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRMLKLVEHPF 121
F M LG+G+F V LV+ G+ +A+K +KK R +E+ E +LK ++H
Sbjct: 23 FIFMEVLGSGAFSEVFLVKQRLTGKLFALKCIKKSPAFRDSSLEN---EIAVLKKIKHEN 79
Query: 122 LIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLALEYLHSHNI 181
++ + ++ + + ++VM + GGELF + + + A +V A++YLH + I
Sbjct: 80 IVTLEDIYESTTHYYLVMQLVSGGELFDRILERGVYTEKDASLVIQQVLSAVKYLHENGI 139
Query: 182 IYRDLKPENILL---DRNGHIKITDFGFAK-EVITVTWTLCGTPDYIAPEVITTKPYNKS 237
++RDLKPEN+L + N I ITDFG +K E + T CGTP Y+APEV+ KPY+K+
Sbjct: 140 VHRDLKPENLLYLTPEENSKIMITDFGLSKMEQNGIMSTACGTPGYVAPEVLAQKPYSKA 199
Query: 238 VDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFFHPDVVDLLGKLITADLT 297
VD WS+G++ + +L GY PFY+ T K +EKI G + F D+ + K L
Sbjct: 200 VDCWSIGVITYILLCGYPPFYEETESKLFEKIKEGYYEFESPFWDDISE-SAKDFICHLL 258
Query: 298 RRLGNLQSGPDDIKSHPW 315
+ N + + SHPW
Sbjct: 259 EKDPNERYTCEKALSHPW 276
>Hs4507275 [D] KOG0580 Serine/threonine protein kinase
Length = 403
Score = 164 bits (416), Expect = 1e-40
Identities = 90/263 (34%), Positives = 144/263 (54%), Gaps = 6/263 (2%)
Query: 54 KGKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRM 113
K ++ L DF+I R LG G FG V+L R + A+KVL K Q+ + E +
Sbjct: 125 KRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEI 184
Query: 114 LKLVEHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLAL 173
+ HP ++R++G F D+ ++++++Y G ++ L+K +F Y E+ AL
Sbjct: 185 QSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANAL 244
Query: 174 EYLHSHNIIYRDLKPENILLDRNGHIKITDFGFAKEV-ITVTWTLCGTPDYIAPEVITTK 232
Y HS +I+RD+KPEN+LL G +KI DFG++ + TLCGT DY+ PE+I +
Sbjct: 245 SYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYLPPEMIEGR 304
Query: 233 PYNKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFFHPDVVDLLGKLI 292
+++ VD WSLG+L +E L G PF T +TY++I E +P F DL+ +L+
Sbjct: 305 MHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLL 364
Query: 293 TADLTRRLGNLQSGPDDIKSHPW 315
+ ++R ++ HPW
Sbjct: 365 KHNPSQR-----PMLREVLEHPW 382
>At4g30960 [T] KOG0583 Serine/threonine protein kinase
Length = 441
Score = 164 bits (416), Expect = 1e-40
Identities = 84/261 (32%), Positives = 146/261 (55%), Gaps = 12/261 (4%)
Query: 62 FQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRMLKLVEHPF 121
+++ R LG G+F +V+ R++ G+ A+KV+ K +++++ ++ E ++++V+HP
Sbjct: 24 YELGRLLGHGTFAKVYHARNIQTGKSVAMKVVGKEKVVKVGMVDQIKREISVMRMVKHPN 83
Query: 122 LIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLALEYLHSHNI 181
++ + ++ M+ + GGELF+ + K R VA+ Y ++ A+++ HS +
Sbjct: 84 IVELHEVMASKSKIYFAMELVRGGELFAKVAKG-RLREDVARVYFQQLISAVDFCHSRGV 142
Query: 182 IYRDLKPENILLDRNGHIKITDFGFAK-----EVITVTWTLCGTPDYIAPEVITTKPYN- 235
+RDLKPEN+LLD G++K+TDFG + + + T CGTP Y+APEVI K Y+
Sbjct: 143 YHRDLKPENLLLDEEGNLKVTDFGLSAFTEHLKQDGLLHTTCGTPAYVAPEVILKKGYDG 202
Query: 236 KSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFFHPDVVDLLGKLITAD 295
D WS G+++F +LAGY PF D + Y KI G+ P + D L+ KL+ +
Sbjct: 203 AKADLWSCGVILFVLLAGYLPFQDDNLVNMYRKIYRGDFKCPGWLSSDARRLVTKLLDPN 262
Query: 296 LTRRLGNLQSGPDDIKSHPWF 316
R+ + + PWF
Sbjct: 263 PNTRI-----TIEKVMDSPWF 278
>At3g29160 [T] KOG0583 Serine/threonine protein kinase
Length = 512
Score = 164 bits (416), Expect = 1e-40
Identities = 87/261 (33%), Positives = 147/261 (55%), Gaps = 8/261 (3%)
Query: 59 LHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRMLKLVE 118
L ++++ +TLG GSFG+V + V G AIK+L + +I M+ E E ++L+L
Sbjct: 17 LPNYKLGKTLGIGSFGKVKIAEHVVTGHKVAIKILNRRKIKNMEMEEKVRREIKILRLFM 76
Query: 119 HPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLALEYLHS 178
HP +IR + + + ++++VM+Y++ GELF + + R A+ + ++ +EY H
Sbjct: 77 HPHIIRQYEVIETTSDIYVVMEYVKSGELFDYIVEKGRLQEDEARNFFQQIISGVEYCHR 136
Query: 179 HNIIYRDLKPENILLDRNGHIKITDFGFAKEVITVTW--TLCGTPDYIAPEVITTKPY-N 235
+ +++RDLKPEN+LLD +IKI DFG + + + T CG+P+Y APEVI+ K Y
Sbjct: 137 NMVVHRDLKPENLLLDSRCNIKIADFGLSNVMRDGHFLKTSCGSPNYAAPEVISGKLYAG 196
Query: 236 KSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFFHPDVVDLLGKLITAD 295
VD WS G++++ +L G PF D ++KI G P + DL+ +++ D
Sbjct: 197 PEVDVWSCGVILYALLCGTLPFDDENIPNLFKKIKGGIYTLPSHLSSEARDLIPRMLIVD 256
Query: 296 LTRRLGNLQSGPDDIKSHPWF 316
+R+ +I+ H WF
Sbjct: 257 PVKRI-----TIPEIRQHRWF 272
>At2g30360 [T] KOG0583 Serine/threonine protein kinase
Length = 435
Score = 164 bits (416), Expect = 1e-40
Identities = 85/276 (30%), Positives = 153/276 (54%), Gaps = 12/276 (4%)
Query: 62 FQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHT-NDERRMLKLVEHP 120
+++ + LG G+F +V R G+ A+K+L K +++ + + E +++ + HP
Sbjct: 21 YELGKLLGCGAFAKVFHARDRRTGQSVAVKILNKKKLLTNPALANNIKREISIMRRLSHP 80
Query: 121 FLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLALEYLHSHN 180
++++ +F M++++GGELF+ + K R +++ Y ++ A+ Y H+
Sbjct: 81 NIVKLHEVMATKSKIFFAMEFVKGGELFNKISKHGRLSEDLSRRYFQQLISAVGYCHARG 140
Query: 181 IIYRDLKPENILLDRNGHIKITDFGFAKEVITV-----TWTLCGTPDYIAPEVITTKPY- 234
+ +RDLKPEN+L+D NG++K++DFG + + TLCGTP Y+APE+++ K Y
Sbjct: 141 VYHRDLKPENLLIDENGNLKVSDFGLSALTDQIRPDGLLHTLCGTPAYVAPEILSKKGYE 200
Query: 235 NKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFFHPDVVDLLGKLITA 294
VD WS GI++F ++AGY PF D M Y+KI GE +P + PD+ + +L+
Sbjct: 201 GAKVDVWSCGIVLFVLVAGYLPFNDPNVMNMYKKIYKGEYRFPRWMSPDLKRFVSRLLDI 260
Query: 295 DLTRRLGNLQSGPDDIKSHPWFAEVIWEKLVAKDIE 330
+ R+ D+I PWF ++++ D E
Sbjct: 261 NPETRI-----TIDEILKDPWFVRGGFKQIKFHDDE 291
>At5g07070 [T] KOG0583 Serine/threonine protein kinase
Length = 456
Score = 164 bits (415), Expect = 2e-40
Identities = 93/295 (31%), Positives = 159/295 (53%), Gaps = 18/295 (6%)
Query: 62 FQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRMLKLVEHPF 121
+++ R LG G+F +V+ RS H AIK++ K +++R+ + E ++++ +HP
Sbjct: 12 YEVGRLLGQGTFAKVYFGRSNHTNESVAIKMIDKDKVMRVGLSQQIKREISVMRIAKHPN 71
Query: 122 LIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLALEYLHSHNI 181
++ ++ ++ V++Y +GGELF+ + K + VA Y ++ A+++ HS +
Sbjct: 72 VVELYEVMATKSRIYFVIEYCKGGELFNKVAKG-KLKEDVAWKYFYQLISAVDFCHSRGV 130
Query: 182 IYRDLKPENILLDRNGHIKITDFGFA-----KEVITVTWTLCGTPDYIAPEVITTKPY-N 235
+RD+KPEN+LLD N ++K++DFG + K + T CGTP Y+APEVI K Y
Sbjct: 131 YHRDIKPENLLLDDNDNLKVSDFGLSALADCKRQDGLLHTTCGTPAYVAPEVINRKGYEG 190
Query: 236 KSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFFHPDVVDLLGKLITAD 295
D WS G+++F +LAGY PF+D M+ Y KI + P +F P+V LL K++ +
Sbjct: 191 TKADIWSCGVVLFVLLAGYLPFHDTNLMEMYRKIGKADFKCPSWFAPEVKRLLCKMLDPN 250
Query: 296 LTRRLGNLQSGPDDIKSHPWFAEVI------WEKLVAKDIETPYEPPIAVGVGDS 344
R+ + IK WF + + EK+ + + P A G G +
Sbjct: 251 HETRITIAK-----IKESSWFRKGLHLKQKKMEKMEKQQVREATNPMEAGGSGQN 300
>Hs5453964 [T] KOG0583 Serine/threonine protein kinase
Length = 550
Score = 164 bits (414), Expect = 3e-40
Identities = 92/280 (32%), Positives = 151/280 (53%), Gaps = 13/280 (4%)
Query: 52 VSKGKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDER 111
V G Y L D TLG G+FG+V + + G A+K+L + +I + + E
Sbjct: 13 VKIGHYILGD-----TLGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGKIRREI 67
Query: 112 RMLKLVEHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTL 171
+ LKL HP +I+++ ++FMVM+Y+ GGELF + K+ R ++ ++
Sbjct: 68 QNLKLFRHPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILS 127
Query: 172 ALEYLHSHNIIYRDLKPENILLDRNGHIKITDFGFAKEVITVTW--TLCGTPDYIAPEVI 229
++Y H H +++RDLKPEN+LLD + + KI DFG + + + T CG+P+Y APEVI
Sbjct: 128 GVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVI 187
Query: 230 TTKPY-NKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFFHPDVVDLL 288
+ + Y VD WS G++++ +L G PF D ++KI G P + +P V+ LL
Sbjct: 188 SGRLYAGPEVDIWSSGVILYALLCGTLPFDDDHVPTLFKKICDGIFYTPQYLNPSVISLL 247
Query: 289 GKLITADLTRRLGNLQSGPDDIKSHPWFAEVIWEKLVAKD 328
++ D +R + DI+ H WF + + + L +D
Sbjct: 248 KHMLQVDPMKR-----ASIKDIREHEWFKQDLPKYLFPED 282
>At5g01810 [T] KOG0583 Serine/threonine protein kinase
Length = 421
Score = 164 bits (414), Expect = 3e-40
Identities = 88/277 (31%), Positives = 155/277 (55%), Gaps = 12/277 (4%)
Query: 54 KGKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRM 113
KG + +++ + LG G+F +V+ R + G AIKV+ K +I+++ E E
Sbjct: 4 KGSVLMLRYEVGKFLGQGTFAKVYHARHLKTGDSVAIKVIDKERILKVGMTEQIKREISA 63
Query: 114 LKLVEHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLAL 173
++L+ HP ++ + ++ VM++++GGELF+ + + + VA+ Y ++ A+
Sbjct: 64 MRLLRHPNIVELHEVMATKSKIYFVMEHVKGGELFNKV-STGKLREDVARKYFQQLVRAV 122
Query: 174 EYLHSHNIIYRDLKPENILLDRNGHIKITDFGF-----AKEVITVTWTLCGTPDYIAPEV 228
++ HS + +RDLKPEN+LLD +G++KI+DFG ++ + T CGTP Y+APEV
Sbjct: 123 DFCHSRGVCHRDLKPENLLLDEHGNLKISDFGLSALSDSRRQDGLLHTTCGTPAYVAPEV 182
Query: 229 ITTKPYNK-SVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFFHPDVVDL 287
I+ Y+ D WS G+++F +LAGY PF D M+ Y+KI EV +P + P L
Sbjct: 183 ISRNGYDGFKADVWSCGVILFVLLAGYLPFRDSNLMELYKKIGKAEVKFPNWLAPGAKRL 242
Query: 288 LGKLITADLTRRLGNLQSGPDDIKSHPWFAEVIWEKL 324
L +++ + R+ + I WF + + E++
Sbjct: 243 LKRILDPNPNTRVST-----EKIMKSSWFRKGLQEEV 274
>SPAC24B11.11c [R] KOG0605 NDR and related serine/threonine kinases
Length = 607
Score = 163 bits (413), Expect = 3e-40
Identities = 107/368 (29%), Positives = 176/368 (47%), Gaps = 69/368 (18%)
Query: 40 QQKESLLPQRSTVSKGKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQII 99
+++ L +R+ +S G DFQ + +G G +G V L R A+K++ K +
Sbjct: 191 RERVYLRKRRTRISHG-----DFQTITQVGQGGYGSVWLARKRDTKEIVALKIMNKSVLH 245
Query: 100 RMKQIEHTNDERRMLKLVEHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPN 159
+M +I H ER +L +L+R+ FQD+ N+++ M+++ GG+ +LL S +
Sbjct: 246 KMDEIRHVLTERDILTTANSEWLVRLLYAFQDTSNIYLAMEFVPGGDFRTLLSNSGVLRD 305
Query: 160 PVAKFYAAEVTLALEYLHSHNIIYRDLKPENILLDRNGHIKITDFGFAKEVIT------- 212
AKFYA E+ LA++ LH I+RDLKPEN L+ +GHIK+TDFG + +I+
Sbjct: 306 HHAKFYATEMFLAIDALHQLGYIHRDLKPENFLVGASGHIKLTDFGLSSGIISKKKIESM 365
Query: 213 ---------------------------------VTWTLCGTPDYIAPEVITTKPYNKSVD 239
++ G+PDY+APEV+ + YN SVD
Sbjct: 366 KIRLQEVNNVVVPERSMRERRQVFRTLLSQDPVYAHSVVGSPDYMAPEVLRGENYNHSVD 425
Query: 240 WWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVY--PPFFHP---------DVVDLL 288
+WSLG +++E L+G+ PF +T+ + + P + P D D +
Sbjct: 426 YWSLGCIMYECLSGFPPFSGSNVNETWSNLKNWRKCFQRPHYDDPRDLEFNWRDDAWDFV 485
Query: 289 GKLITADLTRRLGNLQSGPDDIKSHPWFAEVIWEKLVAKDIETPYEPPIAVGVG---DSS 345
IT D R +L+ + HP+F+++ W K++ T Y PP + D+
Sbjct: 486 CHCIT-DPKDRFCSLK----QVMQHPYFSKIDW-----KNVRTAYRPPFVPDLNSEIDAG 535
Query: 346 LFDQYPEE 353
FD + E
Sbjct: 536 YFDDFTNE 543
>CE28643 [T] KOG0583 Serine/threonine protein kinase
Length = 564
Score = 162 bits (410), Expect = 7e-40
Identities = 96/319 (30%), Positives = 165/319 (51%), Gaps = 14/319 (4%)
Query: 54 KGKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYY--AIKVLKKHQIIRMKQIEHTNDER 111
K + + + + TLG G+FG+V + +H Y A+K+L + +I + + E
Sbjct: 17 KAQIKIGHYILKETLGVGTFGKVKV--GIHETTQYKVAVKILNRQKIKSLDVVGKIRREI 74
Query: 112 RMLKLVEHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTL 171
+ L L HP +IR++ ++FM+M+++ GGELF + K R A+ + ++
Sbjct: 75 QNLSLFRHPHIIRLYQVISTPSDIFMIMEHVSGGELFDYIVKHGRLKTAEARRFFQQIIS 134
Query: 172 ALEYLHSHNIIYRDLKPENILLDRNGHIKITDFGFAKEVITVTW--TLCGTPDYIAPEVI 229
++Y H H +++RDLKPEN+LLD ++KI DFG + + + T CG+P+Y APEVI
Sbjct: 135 GVDYCHRHMVVHRDLKPENLLLDEQNNVKIADFGLSNIMTDGDFLRTSCGSPNYAAPEVI 194
Query: 230 TTKPY-NKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFFHPDVVDLL 288
+ K Y VD WS G++++ +L G PF D + KI +G P F +V+LL
Sbjct: 195 SGKLYAGPEVDVWSCGVILYALLCGTLPFDDEHVPSLFRKIKSGVFPTPDFLERPIVNLL 254
Query: 289 GKLITADLTRRLGNLQSGPDDIKSHPWFAEVIWEKLVAKDIETPYEPPIAVGVGDSSLFD 348
++ D +R + D+ +H WF + + L E+ V + + F
Sbjct: 255 HHMLCVDPMKR-----ATIKDVIAHEWFQKDLPNYLFPPINESEASIVDIEAVREVTEFQ 309
Query: 349 QY--PEEQLDYGVQGEDPY 365
+Y EE++ + G+DP+
Sbjct: 310 RYHVAEEEVTSALLGDDPH 328
>At2g34650 [R] KOG0610 Putative serine/threonine protein kinase
Length = 438
Score = 161 bits (408), Expect = 1e-39
Identities = 103/325 (31%), Positives = 161/325 (48%), Gaps = 67/325 (20%)
Query: 58 TLHDFQIMRTLGTGSFGRVHLVRSVHN-----GRYYAIKVLKKHQIIRMKQIEHTNDERR 112
T DF++MR +G G G V+L R + Y+A+KV+ K + K++ E+
Sbjct: 71 TFRDFRLMRRIGAGDIGTVYLCRLAGDEEESRSSYFAMKVVDKEALALKKKMHRAEMEKT 130
Query: 113 MLKLVEHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKS--QRFPNPVAKFYAAEVT 170
+LK+++HPFL ++ F+ S +VM+Y GG+L SL + +RF A+FYAAEV
Sbjct: 131 ILKMLDHPFLPTLYAEFEASHFSCIVMEYCSGGDLHSLRHRQPHRRFSLSSARFYAAEVL 190
Query: 171 LALEYLHSHNIIYRDLKPENILLDRNGHIKITDFGF------------------------ 206
+ALEYLH IIYRDLKPENIL+ +GHI ++DF
Sbjct: 191 VALEYLHMLGIIYRDLKPENILVRSDGHIMLSDFDLSLCSDSIAAVESSSSSPENQQLRS 250
Query: 207 ----------------AKEVITV--------------TWTLCGTPDYIAPEVITTKPYNK 236
+K+V T+ + + GT +Y+APEV + +
Sbjct: 251 PRRFTRLARLFQRVLRSKKVQTLEPTRLFVAEPVTARSGSFVGTHEYVAPEVASGGSHGN 310
Query: 237 SVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYP-----PFFHPDVVDLLGKL 291
+VDWW+ G+ ++EM+ G TPF T I+ ++ +P F +L+ L
Sbjct: 311 AVDWWAFGVFLYEMIYGKTPFVAPTNDVILRNIVKRQLSFPTDSPATMFELHARNLISGL 370
Query: 292 ITADLTRRLGNLQSGPDDIKSHPWF 316
+ D T+RLG+ + G ++K HP+F
Sbjct: 371 LNKDPTKRLGS-RRGAAEVKVHPFF 394
>YDR466w [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 898
Score = 161 bits (407), Expect = 2e-39
Identities = 96/299 (32%), Positives = 156/299 (52%), Gaps = 38/299 (12%)
Query: 56 KYTLHDFQIMRTLGTGSFGRVHLVRSVHN-GRYYAIKVLKKHQIIRMKQIEHTNDERRML 114
K + HDF LG GS+ V + + YAIKV K II+ ++++ E+ +
Sbjct: 5 KRSPHDFIFKEELGHGSYSTVFKALDKKSPNKIYAIKVCSKKHIIKEAKVKYVTIEKNTM 64
Query: 115 KLV---EHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTL 171
L+ H +I+++ TF D NL+ V+D+ GGEL SLL K F + + + A++
Sbjct: 65 NLLAQKHHAGIIKLYYTFHDEENLYFVLDFAPGGELLSLLHKMGTFNDIWTRHFTAQLID 124
Query: 172 ALEYLHSHNIIYRDLKPENILLDRNGHIKITDFGFAKEVITV------------------ 213
ALE++HSH II+RDLKPEN+LLDR+G + ITDFG A +
Sbjct: 125 ALEFIHSHGIIHRDLKPENVLLDRDGRLMITDFGAAATIDPSLSGDSAKFNSDSNGSKDN 184
Query: 214 --TWTLCGTPDYIAPEVITTKPYNKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILA 271
+ GT +Y++PE++ D W+LG +I++ + G PF +KT+EKI+A
Sbjct: 185 QNCASFVGTAEYVSPELLLYNQCGYGSDIWALGCMIYQFVQGQPPFRGENELKTFEKIVA 244
Query: 272 GEVVYPPF---------FHPDVVDLLGKLITADLTRRLGNLQSGPDDIKSHPWFAEVIW 321
+ + P +P V++L+ K++ ++ R+ + IK HP+F++V W
Sbjct: 245 LDYPWGPNNRINNSTSPINPLVINLVQKILVIEVNERI-----SLEQIKRHPYFSKVDW 298
>Hs4885349 [T] KOG0986 G protein-coupled receptor kinase
Length = 590
Score = 161 bits (407), Expect = 2e-39
Identities = 104/302 (34%), Positives = 160/302 (52%), Gaps = 9/302 (2%)
Query: 58 TLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRMLKLV 117
T + F+ R LG G FG V + G+ YA K L+K +I + K +E+++L+ V
Sbjct: 182 TKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKRLEKKRIKKRKGESMALNEKQILEKV 241
Query: 118 EHPFLIRMWGTFQDSRNLFMVMDYIEGGEL-FSLLRKSQR-FPNPVAKFYAAEVTLALEY 175
F++ + ++ L +V+ + GG+L F + F A FYAAE+ LE
Sbjct: 242 NSQFVVNLAYAYETKDALCLVLTIMNGGDLKFHIYNMGNPGFEEERALFYAAEILCGLED 301
Query: 176 LHSHNIIYRDLKPENILLDRNGHIKITDFGFAKEVI--TVTWTLCGTPDYIAPEVITTKP 233
LH N +YRDLKPENILLD GHI+I+D G A ++ + GT Y+APEV+ +
Sbjct: 302 LHRENTVYRDLKPENILLDDYGHIRISDLGLAVKIPEGDLIRGRVGTVGYMAPEVLNNQR 361
Query: 234 YNKSVDWWSLGILIFEMLAGYTPF----YDVTPMKTYEKILAGEVVYPPFFHPDVVDLLG 289
Y S D+W LG LI+EM+ G +PF V + ++L E VY F + +
Sbjct: 362 YGLSPDYWGLGCLIYEMIEGQSPFRGRKEKVKREEVDRRVLETEEVYSHKFSEEAKSICK 421
Query: 290 KLITADLTRRLGNLQSGPDDIKSHPWFAEVIWEKLVAKDIETPYEP-PIAVGVGDSSLFD 348
L+T D +RLG + G ++K HP+F + +++L A ++ P+ P P AV D +
Sbjct: 422 MLLTKDAKQRLGCQEEGAAEVKRHPFFRNMNFKRLEAGMLDPPFVPDPRAVYCKDVLDIE 481
Query: 349 QY 350
Q+
Sbjct: 482 QF 483
>CE07458 [T] KOG0583 Serine/threonine protein kinase
Length = 562
Score = 161 bits (407), Expect = 2e-39
Identities = 98/328 (29%), Positives = 165/328 (49%), Gaps = 34/328 (10%)
Query: 54 KGKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYY--AIKVLKKHQIIRMKQIEHTNDER 111
K + + + + TLG G+FG+V + +H Y A+K+L + +I + + E
Sbjct: 17 KAQIKIGHYILKETLGVGTFGKVKV--GIHETTQYKVAVKILNRQKIKSLDVVGKIRREI 74
Query: 112 RMLKLVEHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTL 171
+ L L HP +IR++ ++FM+M+++ GGELF + K R A+ + ++
Sbjct: 75 QNLSLFRHPHIIRLYQVISTPSDIFMIMEHVSGGELFDYIVKHGRLKTAEARRFFQQIIS 134
Query: 172 ALEYLHSHNIIYRDLKPENILLDRNGHIKITDFGFAKEVITVTW--TLCGTPDYIAPEVI 229
++Y H H +++RDLKPEN+LLD ++KI DFG + + + T CG+P+Y APEVI
Sbjct: 135 GVDYCHRHMVVHRDLKPENLLLDEQNNVKIADFGLSNIMTDGDFLRTSCGSPNYAAPEVI 194
Query: 230 TTKPY-NKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFFHPDVVDLL 288
+ K Y VD WS G++++ +L G PF D + KI +G P F +V+LL
Sbjct: 195 SGKLYAGPEVDVWSCGVILYALLCGTLPFDDEHVPSLFRKIKSGVFPTPDFLERPIVNLL 254
Query: 289 GKLITADLTRRLGNLQSGPDDIKSHPWFAEVIWEKLVAKDIETPYEPPIAVGVGDSSLFD 348
++ D +R + D+ +H WF KD+ PPI ++S+ D
Sbjct: 255 HHMLCVDPMKR-----ATIKDVIAHEWF---------QKDLPNYLFPPI--NESEASIVD 298
Query: 349 -----------QYPEEQLDYGVQGEDPY 365
EE++ + G+DP+
Sbjct: 299 IEAVREVTERYHVAEEEVTSALLGDDPH 326
>At5g58380 [T] KOG0583 Serine/threonine protein kinase
Length = 464
Score = 161 bits (407), Expect = 2e-39
Identities = 84/245 (34%), Positives = 144/245 (58%), Gaps = 7/245 (2%)
Query: 62 FQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRMLKLVEHPF 121
+ + R LG G+F +V+ RS+ + AIK++ K +++++ IE E ++++ HP
Sbjct: 12 YDVGRLLGQGTFAKVYYGRSILTNQSVAIKMIDKEKVMKVGLIEQIKREISVMRIARHPN 71
Query: 122 LIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLALEYLHSHNI 181
++ ++ ++ VM+Y +GGELF+ + K + + VA Y ++ A+++ HS +
Sbjct: 72 VVELYEVMATKTRIYFVMEYCKGGELFNKVAKG-KLRDDVAWKYFYQLINAVDFCHSREV 130
Query: 182 IYRDLKPENILLDRNGHIKITDFGFA-----KEVITVTWTLCGTPDYIAPEVITTKPYN- 235
+RD+KPEN+LLD N ++K++DFG + K + T CGTP Y+APEVI K Y+
Sbjct: 131 YHRDIKPENLLLDDNENLKVSDFGLSALADCKRQDGLLHTTCGTPAYVAPEVINRKGYDG 190
Query: 236 KSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFFHPDVVDLLGKLITAD 295
D WS G+++F +LAGY PF+D M+ Y KI + P +F P+V LL K++ +
Sbjct: 191 TKADIWSCGVVLFVLLAGYLPFHDSNLMEMYRKIGKADFKAPSWFAPEVRRLLCKMLDPN 250
Query: 296 LTRRL 300
R+
Sbjct: 251 PETRI 255
>SPCC576.15c [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 592
Score = 160 bits (406), Expect = 2e-39
Identities = 111/326 (34%), Positives = 164/326 (50%), Gaps = 36/326 (11%)
Query: 28 TVGSQSTDYLLAQQK-ESLLPQRSTV--SKGKYT-----LHDFQIMRTLGTGSFGRVHLV 79
T ++ST + + K S +P ST S G T + DF+ LG GS+ V
Sbjct: 57 TTPNESTSQIDSSPKIPSAVPHISTPNPSSGASTPNIKRVSDFKFGEILGEGSYSTVLTA 116
Query: 80 RSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRMLKLV-EHPFLIRMWGTFQDSRNLFMV 138
R YAIKVL K II+ K+ ++ N E+ L ++ +HP I+++ TFQD+ NL+ V
Sbjct: 117 TENSTKREYAIKVLDKRHIIKEKKEKYVNIEKEALCILSKHPGFIKLFYTFQDAHNLYFV 176
Query: 139 MDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLALEYLHSHNIIYRDLKPENILLDRNGH 198
+ GEL + K RF A++YAA + +++Y+H +I+RDLKPENILLD N
Sbjct: 177 LSLARNGELLDYINKLGRFNEICAQYYAALIVDSIDYMHGRGVIHRDLKPENILLDDNMR 236
Query: 199 IKITDFGFAKEVITV-----------------TWTLCGTPDYIAPEVITTKPYNKSVDWW 241
KITDFG AK + + + + GT Y++PEV++ K + D W
Sbjct: 237 TKITDFGSAKILNSSHGSHEEDTHHADKPQAHSRSFVGTARYVSPEVLSDKIAGTASDIW 296
Query: 242 SLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFFHPDVVDLLGKLITADLTRRLG 301
+ G ++F+MLAG PF T++ IL PP DL+ KL+ D RL
Sbjct: 297 AFGCILFQMLAGKPPFVAGNEYLTFQSILHLSYEIPPDISDVASDLIKKLLVLDPKDRL- 355
Query: 302 NLQSGPDDIKSHPWFAEV-----IWE 322
D+I HP+F + +WE
Sbjct: 356 ----TVDEIHQHPFFNGIKFDNTLWE 377
>Hs18552621 [R] KOG0597 Serine-threonine protein kinase FUSED
Length = 1315
Score = 160 bits (406), Expect = 2e-39
Identities = 94/280 (33%), Positives = 155/280 (54%), Gaps = 12/280 (4%)
Query: 59 LHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRMLKLVE 118
+ + ++ +G GSFGRV+ R ++ + A+K + K K++ + E +++ +
Sbjct: 1 MEKYHVLEMIGEGSFGRVYKGRRKYSAQVVALKFIPKLGRSE-KELRNLQREIEIMRGLR 59
Query: 119 HPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLALEYLHS 178
HP ++ M +F+ + + +V DY EG ELF +L + P + AA++ AL YLHS
Sbjct: 60 HPNIVHMLDSFETDKEVVVVTDYAEG-ELFQILEDDGKLPEDQVQAIAAQLVSALYYLHS 118
Query: 179 HNIIYRDLKPENILLDRNGHIKITDFGFAKEVITVTWTLC---GTPDYIAPEVITTKPYN 235
H I++RD+KP+NILL + G IK+ DFGFA+ + T T L GTP Y++PE++ +PY+
Sbjct: 119 HRILHRDMKPQNILLAKGGGIKLCDFGFARAMSTNTMVLTSIKGTPLYMSPELVEERPYD 178
Query: 236 KSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFFHPDVVDLLGKLITAD 295
+ D WS+G +++E+ G PFY + + IL V +P P + L L+T D
Sbjct: 179 HTADLWSVGCILYELAVGTPPFYATSIFQLVSLILKDPVRWPSTISPCFKNFLQGLLTKD 238
Query: 296 LTRRLGNLQSGPDDIKSHPWFA--EVIWEKLVAKDIETPY 333
+RL S P D+ HP+ A I + D+ TP+
Sbjct: 239 PRQRL----SWP-DLLYHPFIAGHVTIITEPAGPDLGTPF 273
>Hs5453966 [T] KOG0583 Serine/threonine protein kinase
Length = 552
Score = 159 bits (403), Expect = 5e-39
Identities = 93/280 (33%), Positives = 146/280 (51%), Gaps = 13/280 (4%)
Query: 52 VSKGKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDER 111
V G Y L D TLG G+FG+V + G A+K+L + +I + + E
Sbjct: 11 VKIGHYVLGD-----TLGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREI 65
Query: 112 RMLKLVEHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTL 171
+ LKL HP +I+++ + FMVM+Y+ GGELF + K R A+ ++
Sbjct: 66 QNLKLFRHPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILS 125
Query: 172 ALEYLHSHNIIYRDLKPENILLDRNGHIKITDFGFAKEVITVTW--TLCGTPDYIAPEVI 229
A++Y H H +++RDLKPEN+LLD + + KI DFG + + + T CG+P+Y APEVI
Sbjct: 126 AVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYTAPEVI 185
Query: 230 TTKPY-NKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFFHPDVVDLL 288
+ + Y VD WS G++++ +L G PF D ++KI G P + + V LL
Sbjct: 186 SGRLYAGPEVDIWSCGVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPEYLNRSVATLL 245
Query: 289 GKLITADLTRRLGNLQSGPDDIKSHPWFAEVIWEKLVAKD 328
++ D +R + DI+ H WF + + L +D
Sbjct: 246 MHMLQVDPLKR-----ATIKDIREHEWFKQGLPSYLFPED 280
>Hs4885347 [T] KOG0986 G protein-coupled receptor kinase
Length = 500
Score = 158 bits (400), Expect = 1e-38
Identities = 105/302 (34%), Positives = 155/302 (50%), Gaps = 9/302 (2%)
Query: 58 TLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRMLKLV 117
T + F+ R LG G FG V + G+ YA K L+K +I + K +E+R+L+ V
Sbjct: 151 TKNTFRHYRVLGKGGFGEVCACQVRATGKMYACKKLQKKRIKKRKGEAMALNEKRILEKV 210
Query: 118 EHPFLIRMWGTFQDSRNLFMVMDYIEGGEL-FSLLRKSQR-FPNPVAKFYAAEVTLALEY 175
+ F++ + ++ L +V+ + GG+L F + F A FYAAE+ LE
Sbjct: 211 QSRFVVSLAYAYETKDALCLVLTIMNGGDLKFHIYNLGNPGFDEQRAVFYAAELCCGLED 270
Query: 176 LHSHNIIYRDLKPENILLDRNGHIKITDFGFAKEVITVTWT--LCGTPDYIAPEVITTKP 233
L I+YRDLKPENILLD GHI+I+D G A E+ GT Y+APEV+ +
Sbjct: 271 LQRERIVYRDLKPENILLDDRGHIRISDLGLATEIPEGQRVRGRVGTVGYMAPEVVNNEK 330
Query: 234 YNKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYE----KILAGEVVYPPFFHPDVVDLLG 289
Y S DWW LG LI+EM+ G++PF +E +I Y F D +
Sbjct: 331 YTFSPDWWGLGCLIYEMIQGHSPFKKYKEKVKWEEVDQRIKNDTEEYSEKFSEDAKSICR 390
Query: 290 KLITADLTRRLGNLQSGPDDIKSHPWFAEVIWEKLVAKDIETPYEP-PIAVGVGDSSLFD 348
L+T + ++RLG G +K HP F ++ + +L A +E P+ P P AV D +
Sbjct: 391 MLLTKNPSKRLGCRGEGAAGVKQHPVFKDINFRRLEANMLEPPFCPDPHAVYCKDVLDIE 450
Query: 349 QY 350
Q+
Sbjct: 451 QF 452
>At4g33080 [R] KOG0605 NDR and related serine/threonine kinases
Length = 483
Score = 158 bits (400), Expect = 1e-38
Identities = 97/342 (28%), Positives = 165/342 (47%), Gaps = 60/342 (17%)
Query: 52 VSKGKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDER 111
+ + K ++ DF+++ +G G+FG V L R +G YA+K LKK +++ Q+EH ER
Sbjct: 84 LKRNKISVDDFELLTIIGRGAFGEVRLCRERKSGNIYAMKKLKKSEMVMRGQVEHVRAER 143
Query: 112 RMLKLVEHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTL 171
+L VE ++++++ +FQD L+++M+Y+ GG++ +LL + VA+FY A+ L
Sbjct: 144 NLLAEVESHYIVKLYYSFQDPEYLYLIMEYLPGGDMMTLLMREDTLREDVARFYIAQSVL 203
Query: 172 ALEYLHSHNIIYRDLKPENILLDRNGHIKITDFGFAKEV------------ITVTWTLCG 219
A+E +H +N I+RD+KP+N+LLD++GH+K++DFG K + T T+
Sbjct: 204 AIESIHRYNYIHRDIKPDNLLLDKDGHMKLSDFGLCKPLDCRNLPSIQENRATDDETMSE 263
Query: 220 TPDY--IAPEVITTKPY---NKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGE- 273
D P+ + + + + W + TP Y + P +K E
Sbjct: 264 PMDVDRCFPDTDNKRSWRSPQEQLQHWQMNRRKLAFSTVGTPDY-IAPEVLLKKGYGMEC 322
Query: 274 -------------VVYPPFFHPDVVDLLGKLI-------------------------TAD 295
V YPPF+ D + K++ +
Sbjct: 323 DWWSLGAIMYEMLVGYPPFYADDPISTCRKIVHWRNHLKFPEDAKFSSEAKDLICRLLCN 382
Query: 296 LTRRLGNLQSGPDDIKSHPWFAEVIWEKLVAKDIETPYEPPI 337
+ RLG G IK HPWF +V+WEKL ++E Y+P +
Sbjct: 383 VDHRLGT-GGGAQQIKDHPWFKDVVWEKLY--EMEAAYKPEV 421
>Hs20545245 [D] KOG0588 Serine/threonine protein kinase
Length = 795
Score = 158 bits (399), Expect = 1e-38
Identities = 86/258 (33%), Positives = 145/258 (55%), Gaps = 9/258 (3%)
Query: 62 FQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRMLKLVEHPF 121
+++ +TLG G G V L G+ AIK++ + ++ ++ E +LKL+EHP
Sbjct: 51 YRLEKTLGKGQTGLVKLGVHCITGQKVAIKIVNREKLSESVLMK-VEREIAILKLIEHPH 109
Query: 122 LIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLALEYLHSHNI 181
++++ +++ + L++V++++ GGELF L K R A+ + ++ AL++ HS++I
Sbjct: 110 VLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIVSALDFCHSYSI 169
Query: 182 IYRDLKPENILLDRNGHIKITDFGFAKEVI--TVTWTLCGTPDYIAPEVITTKPYN-KSV 238
+RDLKPEN+LLD +I+I DFG A + ++ T CG+P Y PEVI + Y+ +
Sbjct: 170 CHRDLKPENLLLDEKNNIRIADFGMASLQVGDSLLETSCGSPHYACPEVIKGEKYDGRRA 229
Query: 239 DWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFFHPDVVDLLGKLITADLTR 298
D WS G+++F +L G PF D + EK+ G P F PD LL +I + +
Sbjct: 230 DMWSCGVILFALLVGALPFDDDNLRQLLEKVKRGVFHMPHFIPPDCQSLLRGMIEVEPEK 289
Query: 299 RLGNLQSGPDDIKSHPWF 316
RL + I+ HPW+
Sbjct: 290 RL-----SLEQIQKHPWY 302
>CE00847 [T] KOG0583 Serine/threonine protein kinase
Length = 622
Score = 158 bits (399), Expect = 1e-38
Identities = 86/265 (32%), Positives = 139/265 (52%), Gaps = 8/265 (3%)
Query: 55 GKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRML 114
G + +F I T+G G+FG V + G AIK+L + ++ + + T +E L
Sbjct: 17 GHLKIGNFVIKETIGKGAFGAVKRGTHIQTGYDVAIKILNRGRMKGLGTVNKTRNEIDNL 76
Query: 115 KLVEHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLALE 174
+ + HP + R++ ++F+VM+ + GGELFS + + P ++ Y ++ +
Sbjct: 77 QKLTHPHITRLFRVISTPSDIFLVMELVSGGELFSYITRKGALPIRESRRYFQQIISGVS 136
Query: 175 YLHSHNIIYRDLKPENILLDRNGHIKITDFGFAKEVI--TVTWTLCGTPDYIAPEVITTK 232
Y H+H I++RDLKPEN+LLD N +IKI DFG + + + T CG+P+Y APE+I+ K
Sbjct: 137 YCHNHMIVHRDLKPENLLLDANKNIKIADFGLSNYMTDGDLLSTACGSPNYAAPELISNK 196
Query: 233 PY-NKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFFHPDVVDLLGKL 291
Y VD WS G++++ ML G PF D + KI +G P DL+ +
Sbjct: 197 LYVGPEVDLWSCGVILYAMLCGTLPFDDQNVPTLFAKIKSGRYTVPYSMEKQAADLISTM 256
Query: 292 ITADLTRRLGNLQSGPDDIKSHPWF 316
+ D +R + I +H WF
Sbjct: 257 LQVDPVKR-----ADVKRIVNHSWF 276
>YDR490c [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 766
Score = 157 bits (397), Expect = 2e-38
Identities = 98/324 (30%), Positives = 165/324 (50%), Gaps = 42/324 (12%)
Query: 56 KYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRML- 114
K + DF+ LG GS+ V L + +G+ YA+KVL K +IR K++++ E+ L
Sbjct: 119 KMGIKDFKFGEQLGDGSYSSVVLATARDSGKKYAVKVLSKEYLIRQKKVKYVTVEKLALQ 178
Query: 115 KLVEHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLALE 174
KL + +++ TFQD +L+ +++Y G+ L++K A++YA+++ A++
Sbjct: 179 KLNGTKGIFKLFFTFQDEASLYFLLEYAPHGDFLGLIKKYGSLNETCARYYASQIIDAVD 238
Query: 175 YLHSHNIIYRDLKPENILLDRNGHIKITDFGFAK----------------EVITVTWTLC 218
LH+ II+RD+KPENILLD+N +K+TDFG AK ++ + +
Sbjct: 239 SLHNIGIIHRDIKPENILLDKNMKVKLTDFGTAKILPEEPSNTADGKPYFDLYAKSKSFV 298
Query: 219 GTPDYIAPEVITTKPYNKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPP 278
GT +Y++PE++ + D W+ G ++++MLAG PF T++K++ + +
Sbjct: 299 GTAEYVSPELLNDNYTDSRCDIWAFGCILYQMLAGKPPFKAANEYLTFQKVMKIQYAFTA 358
Query: 279 FFHPDVVDLLGKLITADLTRRLGNLQSGPDDIKSHPWFAEVIWEKLVAKDIETPYEPPIA 338
F V DL+ KL+ D RL Q IK+H +F EV +E
Sbjct: 359 GFPQIVKDLVKKLLVRDPNDRLTIKQ-----IKAHLFFHEVNFE---------------- 397
Query: 339 VGVGDSSLFDQYPEEQLDYGVQGE 362
D S++D P E Y + E
Sbjct: 398 ----DGSVWDDNPPEIQPYKINAE 417
>CE28218 [D] KOG0588 Serine/threonine protein kinase
Length = 914
Score = 157 bits (397), Expect = 2e-38
Identities = 84/257 (32%), Positives = 141/257 (54%), Gaps = 9/257 (3%)
Query: 62 FQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRMLKLVEHPF 121
+++ +TLG G G V GR AIK++ K ++ ++ E ++KL+EHP
Sbjct: 47 YKLEKTLGKGQTGLVKTGTHCITGRKVAIKIVNKEKLSE-SVLQKVEREIAIMKLIEHPH 105
Query: 122 LIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLALEYLHSHNI 181
++ ++ +++ + L+++++++ GGELF L + R + A+ + ++ AL++ H+HNI
Sbjct: 106 VLHLYDVYENKKYLYLLLEHVSGGELFDYLVRKGRLMSKEARKFFRQIISALDFCHAHNI 165
Query: 182 IYRDLKPENILLDRNGHIKITDFGFAKEVI--TVTWTLCGTPDYIAPEVITTKPYN-KSV 238
+RDLKPEN+LLD +IK+ DFG A + ++ T CG+P Y PEVI + Y+ +
Sbjct: 166 CHRDLKPENLLLDERNNIKVADFGMASLQVEGSMLETSCGSPHYACPEVIRGEKYDGRKA 225
Query: 239 DWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFFHPDVVDLLGKLITADLTR 298
D WS G++++ +L G PF D EK+ G P F DV LL +I D +
Sbjct: 226 DVWSCGVILYALLVGALPFDDDNLRNLLEKVKRGVFHIPHFVPADVQSLLRAMIEVDPGK 285
Query: 299 RLGNLQSGPDDIKSHPW 315
R D+ HPW
Sbjct: 286 RYSLA-----DVFKHPW 297
>HsM4507279 [D] KOG0580 Serine/threonine protein kinase
Length = 402
Score = 157 bits (396), Expect = 3e-38
Identities = 88/263 (33%), Positives = 140/263 (52%), Gaps = 6/263 (2%)
Query: 54 KGKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRM 113
K L DF+I R LG G FG V+L R + A+KVL K Q+ + E +
Sbjct: 124 KEAVALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEI 183
Query: 114 LKLVEHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLAL 173
+ HP ++R++G F D+ ++++++Y G ++ L+K +F + AL
Sbjct: 184 QSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTANLYNRIANAL 243
Query: 174 EYLHSHNIIYRDLKPENILLDRNGHIKITDFGFAKEV-ITVTWTLCGTPDYIAPEVITTK 232
Y HS +I+RD+KPEN+LL G +KI DFG++ + TLCGT DY+ PE+I +
Sbjct: 244 SYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYLPPEMIEGR 303
Query: 233 PYNKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFFHPDVVDLLGKLI 292
+++ VD WSLG+L +E L G PF T +TY++I E +P F DL+ +L+
Sbjct: 304 MHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLL 363
Query: 293 TADLTRRLGNLQSGPDDIKSHPW 315
+ ++R ++ HPW
Sbjct: 364 KHNPSQR-----PMLREVLEHPW 381
>At2g19400 [R] KOG0605 NDR and related serine/threonine kinases
Length = 545
Score = 156 bits (394), Expect = 5e-38
Identities = 104/374 (27%), Positives = 173/374 (45%), Gaps = 73/374 (19%)
Query: 40 QQKESLLPQRSTVSKGKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQII 99
Q+KE+ + + + + + + DF ++ +G G+FG V L R G YA+K LKK +++
Sbjct: 86 QRKET---EYTRLMRNRLCVDDFDLLSIIGRGAFGEVRLCREKKTGNIYAMKKLKKSEML 142
Query: 100 RMKQIEHTNDERRMLKLVEHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPN 159
Q+EH ER +L V +++++ +FQD L+++M+Y+ GG++ +LL + +
Sbjct: 143 SRGQVEHVRAERNLLAEVASDCIVKLYYSFQDPEYLYLIMEYLSGGDVMTLLMREETLTE 202
Query: 160 PVAKFYAAEVTLALEYLHSHNIIYRDLKPENILLDRNGHIKITDFGFAKEVITVTWTLCG 219
VA+FY A+ LA+E +H HN ++RD+KP+N+LLD+ GH+K++DFG K + +
Sbjct: 203 TVARFYIAQSVLAIESIHKHNYVHRDIKPDNLLLDKYGHMKLSDFGLCKPLDCRNISAMN 262
Query: 220 TPDYIAPEVITTKPYNKSVD-------------W---------WSLGILIFEMLAGYTPF 257
+ + E I N+S+D W W + TP
Sbjct: 263 VNEPLNDENI-----NESIDGDENCSIGRRGRRWKSPLEQLQHWQINRRKLAYSTVGTPD 317
Query: 258 YDVTPMKTYEKILAGE--------------VVYPPFFHPDVVDLLGKLIT---------- 293
Y + P +K E V YPPF+ D V K+++
Sbjct: 318 Y-IAPEVLLKKGYGVECDWWSLGAIMYEMLVGYPPFYSDDPVTTCRKIVSWRTHLVFPEG 376
Query: 294 ---------------ADLTRRLGNLQSGPDDIKSHPWFAEVIWEKLVAKDIETPYEPPIA 338
D RLG+ +G + IK+H WF +V WEKL D P+
Sbjct: 377 ARLTPEARDLICRLLCDSEHRLGSHGAGAEQIKAHTWFKDVEWEKLYEMDAAF---KPVV 433
Query: 339 VGVGDSSLFDQYPE 352
G D+ F ++ E
Sbjct: 434 NGELDTQNFMKFDE 447
>CE01554 [T] KOG0986 G protein-coupled receptor kinase
Length = 642
Score = 155 bits (393), Expect = 7e-38
Identities = 100/316 (31%), Positives = 165/316 (51%), Gaps = 27/316 (8%)
Query: 60 HDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRMLKLVEH 119
H F++ R LG G FG V + +G+ YA+K L+K ++ + + +E+++L+ +
Sbjct: 201 HTFRLYRVLGKGGFGEVCACQVRASGKMYALKKLEKKRVKKRHAETLSLNEKQILQRINS 260
Query: 120 PFLIRMWGTFQDSRNLFMVMDYIEGGEL----FSLLRKSQRFPNPVAKFYAAEVTLALEY 175
PF++ + ++ L +V+ + GG+L ++L+ F +FYAAE+TL L++
Sbjct: 261 PFVVSLAYAYETKDALCLVLTLMNGGDLKFHLYNLMPGG--FDEKRVQFYAAEITLGLQH 318
Query: 176 LHSHNIIYRDLKPENILLDRNGHIKITDFGFAKEV--ITVTWTLCGTPDYIAPEVITTKP 233
LHS I+YRDLKPENILLD GH++I+D G A E+ GT Y+APE++ +
Sbjct: 319 LHSERILYRDLKPENILLDDFGHVRISDLGLAVEIKDNEPIKGRVGTVGYMAPEIVKNER 378
Query: 234 YNKSVDWWSLGILIFEMLAGYTPFYD----VTPMKTYEKILAGEVVYPPFFHPDVVDLLG 289
Y+ VDWW +G LI+EM+ G PF V + ++ + Y F L
Sbjct: 379 YSYGVDWWGVGCLIYEMIEGKAPFRQRKEKVKREEVERRVREDQEKYSEKFSEAARTLCR 438
Query: 290 KLITADL-----TRRLGNLQSGPDDIKSHPWF---------AEVIWEKLVAKDIETPYEP 335
L+ + RR+G + G ++I++HP+F V W+K+ A + P+ P
Sbjct: 439 GLLHKEPGFRLGCRRVGRPEDGAEEIRAHPFFNTADTVTGREPVPWKKMEAGKVTPPFCP 498
Query: 336 -PIAVGVGDSSLFDQY 350
P AV D +Q+
Sbjct: 499 DPRAVYAKDVLDIEQF 514
>At5g01820 [T] KOG0583 Serine/threonine protein kinase
Length = 442
Score = 155 bits (393), Expect = 7e-38
Identities = 90/263 (34%), Positives = 145/263 (54%), Gaps = 12/263 (4%)
Query: 62 FQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRMLKLVEHPF 121
+++ + +G G+F +V+ RS G+ AIKV+ K ++ + + E ++ + HP
Sbjct: 22 YEVGKLVGCGAFAKVYHGRSTATGQSVAIKVVSKQRLQKGGLNGNIQREIAIMHRLRHPS 81
Query: 122 LIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLALEYLHSHNI 181
++R++ +F VM++ +GGELF+ + K RF +++ Y ++ A+ Y HS I
Sbjct: 82 IVRLFEVLATKSKIFFVMEFAKGGELFAKVSKG-RFCEDLSRRYFQQLISAVGYCHSRGI 140
Query: 182 IYRDLKPENILLDRNGHIKITDFGFAKEVITV-----TWTLCGTPDYIAPEVITTKPYN- 235
+RDLKPEN+LLD +KI+DFG + + TLCGTP Y+APEV+ K Y+
Sbjct: 141 FHRDLKPENLLLDEKLDLKISDFGLSALTDQIRPDGLLHTLCGTPAYVAPEVLAKKGYDG 200
Query: 236 KSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFFHPDVVDLLGKLITAD 295
+D WS GI++F + AGY PF D M Y KI GE P + PD+ LL +L+ +
Sbjct: 201 AKIDIWSCGIILFVLNAGYLPFNDHNLMVMYRKIYKGEFRIPKWTSPDLRRLLTRLLDTN 260
Query: 296 LTRRLGNLQSGPDDIKSHPWFAE 318
R+ ++I PWF +
Sbjct: 261 PQTRI-----TIEEIIHDPWFKQ 278
>CE29300 [T] KOG0694 Serine/threonine protein kinase
Length = 431
Score = 155 bits (391), Expect = 1e-37
Identities = 96/316 (30%), Positives = 170/316 (53%), Gaps = 21/316 (6%)
Query: 47 PQRSTVSKGKYTLHDFQIMRTLGTGSFGRVHLVRSVHNG-RYYAIKVLKKHQIIRMKQIE 105
P RS +++ + L R LG GSFG V+ ++H+ R +AIK+ +K +II + +
Sbjct: 111 PTRSVINEKSFVLE-----RQLGRGSFGVVYCASAIHDSERKFAIKMQEKREIISKRAVL 165
Query: 106 HTNDERRMLKLV-EHPFLIRMWGTFQDSRNLFMVMDYIEG--GELFSLLRKSQRFPNPVA 162
E + +L+ HPF+ R + T+Q +L+ ++ Y G G+LFS+ R+
Sbjct: 166 QVKREASIQRLLPSHPFIARTYSTWQTRTHLYSLLQYPTGSTGDLFSVWRQRGSLSEAAI 225
Query: 163 KFYAAEVTLALEYLHSHNIIYRDLKPENILLDRNGHIKITDFGFAKEVI--TVTWTLCGT 220
+ AE+ A+++LH +++IYRD+K EN++LD+ GH + DFG AK++ + T T+CGT
Sbjct: 226 RLIGAELASAIDFLHQNDVIYRDVKLENVVLDQWGHALLIDFGLAKKLKQGSSTGTICGT 285
Query: 221 PDYIAPEVITTKPYNKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFF 280
Y++P+V + Y+ VDWWSLG+L+ +L G P Y + + + + P
Sbjct: 286 LQYMSPDVASGGTYSHYVDWWSLGVLLHILLTGIYP-YPNSEATHHANLKFIDYSTPIGC 344
Query: 281 HPDVVDLLGKLITADLTRRLGNLQSGPDDIKSHPWFAEVIWEKLVAKDIETPYEPPIAVG 340
+ +L+ +++ +T RL + + +HP+F + + KL KD Y P +G
Sbjct: 345 SREFANLMDRMLAVSITHRLCSFTV----LHAHPFFRSIDFSKLEQKD----YTPAAEIG 396
Query: 341 VGDSSLFDQYPEEQLD 356
+ + + E+ LD
Sbjct: 397 NAEYDTYHK-SEDALD 411
>CE29299 [T] KOG0694 Serine/threonine protein kinase
Length = 436
Score = 155 bits (391), Expect = 1e-37
Identities = 96/316 (30%), Positives = 170/316 (53%), Gaps = 21/316 (6%)
Query: 47 PQRSTVSKGKYTLHDFQIMRTLGTGSFGRVHLVRSVHNG-RYYAIKVLKKHQIIRMKQIE 105
P RS +++ + L R LG GSFG V+ ++H+ R +AIK+ +K +II + +
Sbjct: 111 PTRSVINEKSFVLE-----RQLGRGSFGVVYCASAIHDSERKFAIKMQEKREIISKRAVL 165
Query: 106 HTNDERRMLKLV-EHPFLIRMWGTFQDSRNLFMVMDYIEG--GELFSLLRKSQRFPNPVA 162
E + +L+ HPF+ R + T+Q +L+ ++ Y G G+LFS+ R+
Sbjct: 166 QVKREASIQRLLPSHPFIARTYSTWQTRTHLYSLLQYPTGSTGDLFSVWRQRGSLSEAAI 225
Query: 163 KFYAAEVTLALEYLHSHNIIYRDLKPENILLDRNGHIKITDFGFAKEVI--TVTWTLCGT 220
+ AE+ A+++LH +++IYRD+K EN++LD+ GH + DFG AK++ + T T+CGT
Sbjct: 226 RLIGAELASAIDFLHQNDVIYRDVKLENVVLDQWGHALLIDFGLAKKLKQGSSTGTICGT 285
Query: 221 PDYIAPEVITTKPYNKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFF 280
Y++P+V + Y+ VDWWSLG+L+ +L G P Y + + + + P
Sbjct: 286 LQYMSPDVASGGTYSHYVDWWSLGVLLHILLTGIYP-YPNSEATHHANLKFIDYSTPIGC 344
Query: 281 HPDVVDLLGKLITADLTRRLGNLQSGPDDIKSHPWFAEVIWEKLVAKDIETPYEPPIAVG 340
+ +L+ +++ +T RL + + +HP+F + + KL KD Y P +G
Sbjct: 345 SREFANLMDRMLAVSITHRLCSFTV----LHAHPFFRSIDFSKLEQKD----YTPAAEIG 396
Query: 341 VGDSSLFDQYPEEQLD 356
+ + + E+ LD
Sbjct: 397 NAEYDTYHK-SEDALD 411
>7302050 [T] KOG0986 G protein-coupled receptor kinase
Length = 714
Score = 155 bits (391), Expect = 1e-37
Identities = 101/307 (32%), Positives = 160/307 (51%), Gaps = 14/307 (4%)
Query: 58 TLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRMLKLV 117
T F++ R LG G FG V + G+ YA K L+K +I + K E+++L+ +
Sbjct: 305 TYKTFRMYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGESMVLIEKQILQKI 364
Query: 118 EHPFLIRMWGTFQDSRNLFMVMDYIEGGEL-FSLLRKSQR--FPNPVAKFYAAEVTLALE 174
PF++ + ++ L +V+ + GG+L F + F A+FYAAEV L+
Sbjct: 365 NSPFVVNLAYAYETKDALCLVLTIMNGGDLKFHIYNMGGEPGFELERARFYAAEVACGLQ 424
Query: 175 YLHSHNIIYRDLKPENILLDRNGHIKITDFGFAKEVI--TVTWTLCGTPDYIAPEVITTK 232
+LH I+YRD KPENILLD +GH++I+D G A E+ + GT Y+APEVI +
Sbjct: 425 HLHKQGIVYRDCKPENILLDDHGHVRISDLGLAVEIPEGEMVRGRVGTVGYMAPEVIDNE 484
Query: 233 PYNKSVDWWSLGILIFEMLAGYTPF----YDVTPMKTYEKILAGEVVYPPFFHPDVVDLL 288
Y S DW+S G L++EM+ G PF V + ++ Y F+ + +
Sbjct: 485 KYAFSPDWFSFGCLLYEMIEGQAPFRMRKEKVKREEVDRRVKEDPEKYSSKFNDEAKSMC 544
Query: 289 GKLITADLTRRLG--NLQSGPDDIKSHPWF--AEVIWEKLVAKDIETPYEP-PIAVGVGD 343
+L+ + +RLG N + G D+ +HP+F ++ W +L A +E P+ P P AV D
Sbjct: 545 QQLLAKSIKQRLGCRNGRMGGQDVMAHPFFHSTQLNWRRLEAGMLEPPFVPDPHAVYAKD 604
Query: 344 SSLFDQY 350
+Q+
Sbjct: 605 VLDIEQF 611
>At5g57630 [T] KOG0583 Serine/threonine protein kinase
Length = 412
Score = 154 bits (390), Expect = 2e-37
Identities = 81/229 (35%), Positives = 134/229 (58%), Gaps = 4/229 (1%)
Query: 55 GKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRML 114
G + ++I RT+G G+F +V L NG Y A+K++ K +I+ E R +
Sbjct: 5 GTKKIGKYEIGRTIGEGNFAKVKLGYDTTNGTYVAVKIIDKALVIQKGLESQVKREIRTM 64
Query: 115 KLVEHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLALE 174
KL+ HP ++++ + +VM+Y+ GG+L L + + + K + ++ A++
Sbjct: 65 KLLNHPNIVQIHEVIGTKTKICIVMEYVSGGQLSDRLGRQKMKESDARKLF-QQLIDAVD 123
Query: 175 YLHSHNIIYRDLKPENILLDRNGHIKITDFGFA--KEVITVTWTLCGTPDYIAPEVITTK 232
Y H+ + +RDLKP+N+LLD G++K++DFG + + + T CG+P YIAPE+I K
Sbjct: 124 YCHNRGVYHRDLKPQNLLLDSKGNLKVSDFGLSAVPKSGDMLSTACGSPCYIAPELIMNK 183
Query: 233 PYN-KSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFF 280
Y+ +VD WS G+++FE+LAGY PF D T Y+KIL + +PP F
Sbjct: 184 GYSGAAVDVWSCGVILFELLAGYPPFDDHTLPVLYKKILRADYTFPPGF 232
>YPR111w [R] KOG0605 NDR and related serine/threonine kinases
Length = 564
Score = 154 bits (389), Expect = 2e-37
Identities = 105/369 (28%), Positives = 175/369 (46%), Gaps = 63/369 (17%)
Query: 37 LLAQQKESLLPQRSTVSKGKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKH 96
L Q++ +L +R K K DFQI+ +G G +G+V+L + + A+K+L K
Sbjct: 148 LYLQREHEVLRKRRLKPKHK----DFQILTQVGQGGYGQVYLAKKKDSDEICALKILNKK 203
Query: 97 QIIRMKQIEHTNDERRMLKLVEHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQR 156
+ ++ + H ER +L +L+++ FQD +L++ M+++ GG+ +LL ++
Sbjct: 204 LLFKLNETNHVLTERDILTTTRSDWLVKLLYAFQDPESLYLAMEFVPGGDFRTLLINTRI 263
Query: 157 FPNPVAKFYAAEVTLALEYLHSHNIIYRDLKPENILLDRNGHIKITDFGFA--------- 207
+ A+FY +E+ A+ LH +RDLKPEN L+D GHIK+TDFG A
Sbjct: 264 LKSGHARFYISEMFCAVNALHELGYTHRDLKPENFLIDATGHIKLTDFGLAAGTVSNERI 323
Query: 208 ----------------------------------KEVITVTWTLCGTPDYIAPEVITTKP 233
K I ++ G+PDY+A EV+ K
Sbjct: 324 ESMKIRLEEVKNLEFPAFTERSIEDRRKIYHNMRKTEINYANSMVGSPDYMALEVLEGKK 383
Query: 234 YNKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVY--------PPFFHPDVV 285
Y+ +VD+WSLG ++FE L GYTPF + +TYE + + F
Sbjct: 384 YDFTVDYWSLGCMLFESLVGYTPFSGSSTNETYENLRYWKKTLRRPRTEDRRAAFSDRTW 443
Query: 286 DLLGKLITADLTRRLGNLQSGPDDIKSHPWFAEVIWEKLVAKDIETPYEPPIAVGVGDSS 345
DL+ +LI AD R+ + + ++ +FAE+ +E L + P+ P + D+
Sbjct: 444 DLITRLI-ADPINRVRSF----EQVRKMSYFAEINFETL--RTSSPPFIPQLD-DETDAG 495
Query: 346 LFDQYPEEQ 354
FD + E+
Sbjct: 496 YFDDFTNEE 504
>SPCC74.03c [T] KOG0583 Serine/threonine protein kinase
Length = 576
Score = 154 bits (389), Expect = 2e-37
Identities = 96/290 (33%), Positives = 150/290 (51%), Gaps = 19/290 (6%)
Query: 40 QQKESLLPQRSTVSKG----------KYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYA 89
Q +E L + ST+ G K + + I TLG GSFG+V L + A
Sbjct: 2 QPQEVDLMENSTMRNGARVLPPEAISKRHIGPYIIRETLGEGSFGKVKLATHYKTQQKVA 61
Query: 90 IKVLKKHQIIRMKQIEHTNDERRMLKLVEHPFLIRMWGTFQDSRNLFMVMDYIEGGELFS 149
+K + + + + E LKL+ HP +I+++ ++ MV++Y GGELF
Sbjct: 62 LKFISRQLLKKSDMHMRVEREISYLKLLRHPHIIKLYDVITTPTDIVMVIEYA-GGELFD 120
Query: 150 LLRKSQRFPNPVAKFYAAEVTLALEYLHSHNIIYRDLKPENILLDRNGHIKITDFGFAKE 209
+ + +R + + ++ A+EY H H I++RDLKPEN+LLD N ++KI DFG +
Sbjct: 121 YIVEKKRMTEDEGRRFFQQIICAIEYCHRHKIVHRDLKPENLLLDDNLNVKIADFGLSNI 180
Query: 210 VITVTW--TLCGTPDYIAPEVITTKPY-NKSVDWWSLGILIFEMLAGYTPFYDVTPMKTY 266
+ + T CG+P+Y APEVI K Y VD WS GI+++ ML G PF D +
Sbjct: 181 MTDGNFLKTSCGSPNYAAPEVINGKLYAGPEVDVWSCGIVLYVMLVGRLPFDDEFIPNLF 240
Query: 267 EKILAGEVVYPPFFHPDVVDLLGKLITADLTRRLGNLQSGPDDIKSHPWF 316
+K+ + V P F P L+ ++I AD +R+ +Q +I+ PWF
Sbjct: 241 KKVNSCVYVMPDFLSPGAQSLIRRMIVADPMQRI-TIQ----EIRRDPWF 285
>CE27768 [R] KOG0586 Serine/threonine protein kinase
Length = 1096
Score = 154 bits (389), Expect = 2e-37
Identities = 87/278 (31%), Positives = 154/278 (55%), Gaps = 11/278 (3%)
Query: 43 ESLLPQRSTVSKGKYTLH--DFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIR 100
+S + RS + +H +++++T+G G+F +V L + V G AIK++ K +
Sbjct: 101 QSGMSSRSAARRNDQDVHVGKYKLLKTIGKGNFAKVKLAKHVITGHEVAIKIIDK-TALN 159
Query: 101 MKQIEHTNDERRMLKLVEHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNP 160
++ E +++K ++HP +++++ + + L++V++Y GGE+F L R
Sbjct: 160 PSSLQKLFREVKIMKQLDHPNIVKLYQVMETEQTLYLVLEYASGGEVFDYLVAHGRMKEK 219
Query: 161 VAKFYAAEVTLALEYLHSHNIIYRDLKPENILLDRNGHIKITDFGFAK--EVITVTWTLC 218
A+ ++ A++YLHS NII+RDLK EN+LLD++ +IKI DFGF+ + T C
Sbjct: 220 EARAKFRQIVSAVQYLHSKNIIHRDLKAENLLLDQDMNIKIADFGFSNTFSLGNKLDTFC 279
Query: 219 GTPDYIAPEVITTKPYN-KSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYP 277
G+P Y APE+ + K Y+ VD WSLG++++ +++G PF + E++L G+ P
Sbjct: 280 GSPPYAAPELFSGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIP 339
Query: 278 PFFHPDVVDLLGKLITADLTRRLGNLQSGPDDIKSHPW 315
+ D +LL K + + RR S D+I W
Sbjct: 340 FYMSTDCENLLKKFLVINPQRR-----SSLDNIMKDRW 372
>CE23838 [R] KOG0586 Serine/threonine protein kinase
Length = 1192
Score = 154 bits (389), Expect = 2e-37
Identities = 87/278 (31%), Positives = 154/278 (55%), Gaps = 11/278 (3%)
Query: 43 ESLLPQRSTVSKGKYTLH--DFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIR 100
+S + RS + +H +++++T+G G+F +V L + V G AIK++ K +
Sbjct: 149 QSGMSSRSAARRNDQDVHVGKYKLLKTIGKGNFAKVKLAKHVITGHEVAIKIIDK-TALN 207
Query: 101 MKQIEHTNDERRMLKLVEHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNP 160
++ E +++K ++HP +++++ + + L++V++Y GGE+F L R
Sbjct: 208 PSSLQKLFREVKIMKQLDHPNIVKLYQVMETEQTLYLVLEYASGGEVFDYLVAHGRMKEK 267
Query: 161 VAKFYAAEVTLALEYLHSHNIIYRDLKPENILLDRNGHIKITDFGFAK--EVITVTWTLC 218
A+ ++ A++YLHS NII+RDLK EN+LLD++ +IKI DFGF+ + T C
Sbjct: 268 EARAKFRQIVSAVQYLHSKNIIHRDLKAENLLLDQDMNIKIADFGFSNTFSLGNKLDTFC 327
Query: 219 GTPDYIAPEVITTKPYN-KSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYP 277
G+P Y APE+ + K Y+ VD WSLG++++ +++G PF + E++L G+ P
Sbjct: 328 GSPPYAAPELFSGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIP 387
Query: 278 PFFHPDVVDLLGKLITADLTRRLGNLQSGPDDIKSHPW 315
+ D +LL K + + RR S D+I W
Sbjct: 388 FYMSTDCENLLKKFLVINPQRR-----SSLDNIMKDRW 420
>7297776 [D] KOG0580 Serine/threonine protein kinase
Length = 329
Score = 154 bits (389), Expect = 2e-37
Identities = 89/258 (34%), Positives = 135/258 (51%), Gaps = 8/258 (3%)
Query: 61 DFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRMLKLVEHP 120
DF++ LG G FGRV+L R H+ A+KV+ K ++ + E + ++HP
Sbjct: 52 DFEMGAHLGRGKFGRVYLARERHSHYLVAMKVMFKEELRKGCVQRQVLREIEIQSRLKHP 111
Query: 121 FLIRMWGTFQDSRNLFMVMDYIEGGELFSLLR--KSQRFPNPVAKFYAAEVTLALEYLHS 178
++R+ F D +++ ++ GELF LR + RF P + Y +V AL Y H
Sbjct: 112 HILRLLTWFHDESRIYLALEIASEGELFKHLRGAPNHRFDEPRSAKYTYQVANALNYCHL 171
Query: 179 HNIIYRDLKPENILLDRNGHIKITDFGFAKEVIT-VTWTLCGTPDYIAPEVITTKPYNKS 237
+N+I+RDLKPENILL +K+ DFG++ TLCGT DY+ PE++ Y+ S
Sbjct: 172 NNVIHRDLKPENILLTSTDDLKLADFGWSAHTPNNKRRTLCGTLDYLPPEMVDGNSYDDS 231
Query: 238 VDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFFHPDVVDLLGKLITADLT 297
VD W LGIL +E + G PF + TY KI E+ YP +L+G L+ +
Sbjct: 232 VDQWCLGILCYEFVVGCPPFESNSTESTYSKIRRMEISYPSHLSKGCKELIGGLLRKESK 291
Query: 298 RRLGNLQSGPDDIKSHPW 315
R+ + D+ +H W
Sbjct: 292 GRITLV-----DVMTHYW 304
>Hs9966875 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 357
Score = 154 bits (388), Expect = 3e-37
Identities = 89/261 (34%), Positives = 140/261 (53%), Gaps = 8/261 (3%)
Query: 62 FQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRMLKLVEHPF 121
F+ TLGTG+F V L G+ +A+K + K + ++ K+ N E +L+ ++H
Sbjct: 23 FEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPK-KALKGKESSIEN-EIAVLRKIKHEN 80
Query: 122 LIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLALEYLHSHNI 181
++ + ++ +L++VM + GGELF + + + A +V A+ YLH I
Sbjct: 81 IVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGI 140
Query: 182 IYRDLKPENILL---DRNGHIKITDFGFAKEVIT--VTWTLCGTPDYIAPEVITTKPYNK 236
++RDLKPEN+L D I I+DFG +K V T CGTP Y+APEV+ KPY+K
Sbjct: 141 VHRDLKPENLLYYSQDEESKIMISDFGLSKMEGKGDVMSTACGTPGYVAPEVLAQKPYSK 200
Query: 237 SVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFFHPDVVDLLGKLITADL 296
+VD WS+G++ + +L GY PFYD K +E+IL E + + D+ D K +L
Sbjct: 201 AVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISD-SAKDFIRNL 259
Query: 297 TRRLGNLQSGPDDIKSHPWFA 317
+ N + + HPW A
Sbjct: 260 MEKDPNKRYTCEQAARHPWIA 280
>YDR477w [T] KOG0583 Serine/threonine protein kinase
Length = 633
Score = 153 bits (386), Expect = 4e-37
Identities = 91/290 (31%), Positives = 152/290 (52%), Gaps = 15/290 (5%)
Query: 50 STVSKGKYTLHD------FQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQ 103
ST++ K +L D +QI++TLG GSFG+V L G+ A+K++ K + +
Sbjct: 37 STLNNPKSSLADGAHIGNYQIVKTLGEGSFGKVKLAYHTTTGQKVALKIINKKVLAKSDM 96
Query: 104 IEHTNDERRMLKLVEHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAK 163
E L+L+ HP +I+++ + + MV++Y G ELF + + + A+
Sbjct: 97 QGRIEREISYLRLLRHPHIIKLYDVIKSKDEIIMVIEYA-GNELFDYIVQRDKMSEQEAR 155
Query: 164 FYAAEVTLALEYLHSHNIIYRDLKPENILLDRNGHIKITDFGFAKEVITVTW--TLCGTP 221
+ ++ A+EY H H I++RDLKPEN+LLD + ++KI DFG + + + T CG+P
Sbjct: 156 RFFQQIISAVEYCHRHKIVHRDLKPENLLLDEHLNVKIADFGLSNIMTDGNFLKTSCGSP 215
Query: 222 DYIAPEVITTKPY-NKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFF 280
+Y APEVI+ K Y VD WS G++++ ML PF D + ++ I G P F
Sbjct: 216 NYAAPEVISGKLYAGPEVDVWSCGVILYVMLCRRLPFDDESIPVLFKNISNGVYTLPKFL 275
Query: 281 HPDVVDLLGKLITADLTRRLGNLQSGPDDIKSHPWFAEVIWEKLVAKDIE 330
P L+ +++ + R+ + DD WF + E L+ D++
Sbjct: 276 SPGAAGLIKRMLIVNPLNRISIHEIMQDD-----WFKVDLPEYLLPPDLK 320
>Hs8923922 [R] KOG0586 Serine/threonine protein kinase
Length = 795
Score = 153 bits (386), Expect = 4e-37
Identities = 83/247 (33%), Positives = 144/247 (57%), Gaps = 5/247 (2%)
Query: 61 DFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRMLKLVEHP 120
++++ +T+G G+F +V L R V GR A+K++ K Q+ ++ E R++K++ HP
Sbjct: 59 NYRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQL-NPTSLQKLFREVRIMKILNHP 117
Query: 121 FLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLALEYLHSHN 180
+++++ + + L++VM+Y GGE+F L R A+ ++ A++Y H
Sbjct: 118 NIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKY 177
Query: 181 IIYRDLKPENILLDRNGHIKITDFGFAKE--VITVTWTLCGTPDYIAPEVITTKPYN-KS 237
I++RDLK EN+LLD + +IKI DFGF+ E V T CG+P Y APE+ K Y+
Sbjct: 178 IVHRDLKAENLLLDGDMNIKIADFGFSNEFTVGNKLDTFCGSPPYAAPELFQGKKYDGPE 237
Query: 238 VDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFFHPDVVDLLGKLITADLT 297
VD WSLG++++ +++G PF + E++L G+ P + D +LL KL+ +
Sbjct: 238 VDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKLLVLNPI 297
Query: 298 RRLGNLQ 304
+R G+L+
Sbjct: 298 KR-GSLE 303
>SPCC417.06c [R] KOG0605 NDR and related serine/threonine kinases
Length = 624
Score = 152 bits (384), Expect = 8e-37
Identities = 95/344 (27%), Positives = 166/344 (47%), Gaps = 53/344 (15%)
Query: 62 FQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRMLKLVEHPF 121
F ++ LG G +G V L + + A+K++KK + ++ +++H +ER +L +
Sbjct: 162 FDLLVKLGQGGYGSVWLAKKRNTHELLAMKMMKKSTLQQLNEVKHILNERDILTNTNSEW 221
Query: 122 LIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLALEYLHSHNI 181
L++++ FQD +++ M+Y+ GG+ + L +FY AE+ A+ +H
Sbjct: 222 LVKLYYAFQDKEKVYLAMEYVPGGDFRTFLTTKGLLHENQTRFYLAEMVAAISAVHKLGY 281
Query: 182 IYRDLKPENILLDRNGHIKITDFGFAKEVITVTW-------------------------- 215
++RDLKPEN L+D+ GHIK++DFG + ++T
Sbjct: 282 MHRDLKPENFLIDQKGHIKLSDFGLSTAIVTSNQVNRLQHALVSAVNPQRPYLTQKQRRN 341
Query: 216 --------------TLCGTPDYIAPEVITTKPYNKSVDWWSLGILIFEMLAGYTPFYDVT 261
++ G+P+Y+APEV+ K Y+++VD+WSLG + +E L GY PF T
Sbjct: 342 IYKALLEKNENKVNSVVGSPEYMAPEVVYGKKYDRTVDYWSLGCICYECLVGYPPFSGST 401
Query: 262 PMKTYEKILA-GEVVYPPFFHPD---------VVDLLGKLITADLTRRLGNLQSGPDDIK 311
+T+ + E++ P + + V D IT LT QS +I+
Sbjct: 402 LQETWTNLYYWREMLQRPSKNENGIYDKKARSVSDEAWSFITKCLTEPTSRFQS-TIEIQ 460
Query: 312 SHPWFAEVIWEKLVAKDIETPYEPPIAVGVGDSSLFDQYPEEQL 355
HP+F + W L K P+ P + + D+S FD + +EQ+
Sbjct: 461 KHPFFKRLHWNGL-RKRAVPPFVPRLENQL-DTSYFDDFNDEQV 502
>SPCC18B5.11c [D] KOG0615 Serine/threonine protein kinase Chk2 and related
proteins
Length = 460
Score = 152 bits (384), Expect = 8e-37
Identities = 89/275 (32%), Positives = 145/275 (52%), Gaps = 22/275 (8%)
Query: 62 FQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQII----RMKQIEHTNDERRMLKLV 117
++I+RTLG+G+F V L V++G++YAIK++ K +I+ + E E +LK +
Sbjct: 167 YEIIRTLGSGTFAVVKLAVEVNSGKWYAIKIINKRKILLTSSEKRATEMFQREIDILKSL 226
Query: 118 EHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLALEYLH 177
HP +++ F++ LF+VM+Y+EGG+L L + K ++ L +LH
Sbjct: 227 HHPGVVQCHEIFENDDELFIVMEYVEGGDLMDFLIANGSIDEQDCKPLLKQLLETLLHLH 286
Query: 178 SHNIIYRDLKPENILLDRNGHIKITDFGFAKEVI---TVTWTLCGTPDYIAPEVITTK-- 232
+ +RD+KPENIL+ + H+KI+DFG AK + T T CGT Y+APEV+ +K
Sbjct: 287 KQGVTHRDIKPENILITNDFHLKISDFGLAKVIHGTGTFLETFCGTMGYLAPEVLKSKNV 346
Query: 233 ----PYNKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFFHPDV---- 284
Y+ VD WSLG +++ ML PF + K E I G P ++
Sbjct: 347 NLDGGYDDKVDIWSLGCVLYVMLTASIPFASSSQAKCIELISKGAYPIEPLLENEISEEG 406
Query: 285 VDLLGKLITADLTRRLGNLQSGPDDIKSHPWFAEV 319
+DL+ +++ + +R+ + HPWF V
Sbjct: 407 IDLINRMLEINPEKRISE-----SEALQHPWFYTV 436
>7294217 [D] KOG0588 Serine/threonine protein kinase
Length = 851
Score = 152 bits (383), Expect = 1e-36
Identities = 91/278 (32%), Positives = 148/278 (52%), Gaps = 14/278 (5%)
Query: 41 QKESLLPQRSTVSKGKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIR 100
QKE+ + + G Y L +TLG G G V L G+ AIK++ + ++
Sbjct: 2 QKENNVTAENCQFVGPYRLE-----KTLGKGQTGLVKLGVHCVIGKKVAIKIINREKLSE 56
Query: 101 MKQIEHTNDERRMLKLVEHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNP 160
++ E ++KL++HP ++ + +++ + L+++++++ GGELF L K R
Sbjct: 57 SVLMK-VEREIAIMKLIDHPHVLGLSDVYENKKYLYLILEHVSGGELFDYLVKKGRLTPK 115
Query: 161 VAKFYAAEVTLALEYLHSHNIIYRDLKPENILLDRNGHIKITDFGFA--KEVITVTWTLC 218
A+ + ++ AL++ HSH+I +RDLKPEN+LLD +IKI DFG A + ++ T C
Sbjct: 116 EARKFFRQIISALDFCHSHSICHRDLKPENLLLDEKNNIKIADFGMASLQPAGSMLETSC 175
Query: 219 GTPDYIAPEVITTKPYN-KSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYP 277
G+P Y PEVI + Y+ + D WS G++++ +L G PF D + EK+ G P
Sbjct: 176 GSPHYACPEVIRGEKYDGRKADVWSCGVILYALLVGALPFDDDNLRQLLEKVKRGVFHIP 235
Query: 278 PFFHPDVVDLLGKLITADLTRRLGNLQSGPDDIKSHPW 315
F PD LL +I + RRL +I HPW
Sbjct: 236 HFVPPDCQSLLRGMIEVNPDRRLTLA-----EINRHPW 268
>Hs22062450 [R] KOG0586 Serine/threonine protein kinase
Length = 787
Score = 151 bits (381), Expect = 2e-36
Identities = 80/263 (30%), Positives = 149/263 (56%), Gaps = 6/263 (2%)
Query: 42 KESLLPQRSTVSKGKYTLH--DFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQII 99
K +++ R++ + H ++++++T+G G+F +V L R + G+ A+K++ K Q+
Sbjct: 31 KSNMIRGRNSATSADEQPHIGNYRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQL- 89
Query: 100 RMKQIEHTNDERRMLKLVEHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPN 159
++ E R++K++ HP +++++ + + L++VM+Y GGE+F L R
Sbjct: 90 NSSSLQKLFREVRIMKVLNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKE 149
Query: 160 PVAKFYAAEVTLALEYLHSHNIIYRDLKPENILLDRNGHIKITDFGFAKEVI--TVTWTL 217
A+ ++ A++Y H I++RDLK EN+LLD + +IKI DFGF+ E T
Sbjct: 150 KEARAKFRQIVSAVQYCHQKFIVHRDLKAENLLLDADMNIKIADFGFSNEFTFGNKLDTF 209
Query: 218 CGTPDYIAPEVITTKPYN-KSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVY 276
CG+P Y APE+ K Y+ VD WSLG++++ +++G PF + E++L G+
Sbjct: 210 CGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRI 269
Query: 277 PPFFHPDVVDLLGKLITADLTRR 299
P + D +LL K + + ++R
Sbjct: 270 PFYMSTDCENLLKKFLILNPSKR 292
>CE25046 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 348
Score = 151 bits (381), Expect = 2e-36
Identities = 90/285 (31%), Positives = 155/285 (53%), Gaps = 13/285 (4%)
Query: 38 LAQQKESLLPQRSTVSKGKYTLHDFQIMRTLGTGSFGRVHLVRSVHN-GRYYAIKVLKKH 96
L ++++ P + + KY D LGTG+F +V L S + G+ YA+K + K
Sbjct: 3 LFKRRDGSGPAPNATIREKYDFRD-----VLGTGAFSKVFLAESKSDAGQMYAVKCIDK- 56
Query: 97 QIIRMKQIEHTNDERRMLKLVEHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQR 156
+ ++ K+ E +E ++L+ + H +++++ T+ + + +++VM+ + GGELF +
Sbjct: 57 KALKGKE-ESLENEIKVLRKLRHNNIVQLFDTYDEKQFVYLVMELVTGGELFDRIVAKGS 115
Query: 157 FPNPVAKFYAAEVTLALEYLHSHNIIYRDLKPENILL---DRNGHIKITDFGFAK-EVIT 212
+ A +V A+ ++H + +++RDLKPEN+L D + I I+DFG +K E
Sbjct: 116 YTEQDASNLIRQVLEAVGFMHDNGVVHRDLKPENLLYYNQDEDSKIMISDFGLSKTEDSG 175
Query: 213 VTWTLCGTPDYIAPEVITTKPYNKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAG 272
V T CGTP Y+APEV+ KPY K+VD WS+G++ + +L GY PFYD + + +I+ G
Sbjct: 176 VMATACGTPGYVAPEVLQQKPYGKAVDVWSIGVIAYILLCGYPPFYDESDANLFAQIIKG 235
Query: 273 EVVYPPFFHPDVVDLLGKLITADLTRRLGNLQSGPDDIKSHPWFA 317
E + + + D IT L + D SHPW +
Sbjct: 236 EYEFDAPYWDQISDSAKDFIT-HLMCCDPEARFTCQDALSHPWIS 279
>7302464 [R] KOG0586 Serine/threonine protein kinase
Length = 739
Score = 151 bits (381), Expect = 2e-36
Identities = 78/241 (32%), Positives = 140/241 (57%), Gaps = 4/241 (1%)
Query: 62 FQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRMLKLVEHPF 121
+++++T+G G+F +V L + + G+ AIK++ K Q+ ++ E R++K+++HP
Sbjct: 151 YKLIKTIGKGNFAKVKLAKHLPTGKEVAIKIIDKTQL-NPGSLQKLFREVRIMKMLDHPN 209
Query: 122 LIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLALEYLHSHNI 181
+++++ + + L+++M+Y GGE+F L R A+ ++ A++Y H I
Sbjct: 210 IVKLFQVIETEKTLYLIMEYASGGEVFDYLVLHGRMKEKEARVKFRQIVSAVQYCHQKRI 269
Query: 182 IYRDLKPENILLDRNGHIKITDFGFAKEVI--TVTWTLCGTPDYIAPEVITTKPYN-KSV 238
I+RDLK EN+LLD +IKI DFGF+ E + T CG+P Y APE+ K Y+ V
Sbjct: 270 IHRDLKAENLLLDSELNIKIADFGFSNEFTPGSKLDTFCGSPPYAAPELFQGKKYDGPEV 329
Query: 239 DWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFFHPDVVDLLGKLITADLTR 298
D WSLG++++ +++G PF T + E++L G+ P + D +LL K + + +
Sbjct: 330 DVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLRKFLVLNPAK 389
Query: 299 R 299
R
Sbjct: 390 R 390
>Hs9845489 [R] KOG0586 Serine/threonine protein kinase
Length = 691
Score = 150 bits (379), Expect = 3e-36
Identities = 77/242 (31%), Positives = 140/242 (57%), Gaps = 4/242 (1%)
Query: 61 DFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRMLKLVEHP 120
++++++T+G G+F +V L R + G+ A+K++ K Q+ ++ E R++K++ HP
Sbjct: 19 NYRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQL-NSSSLQKLFREVRIMKVLNHP 77
Query: 121 FLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLALEYLHSHN 180
+++++ + + L++VM+Y GGE+F L R A+ ++ A++Y H
Sbjct: 78 NIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKF 137
Query: 181 IIYRDLKPENILLDRNGHIKITDFGFAKEVI--TVTWTLCGTPDYIAPEVITTKPYN-KS 237
I++RDLK EN+LLD + +IKI DFGF+ E T CG+P Y APE+ K Y+
Sbjct: 138 IVHRDLKAENLLLDADMNIKIADFGFSNEFTFGNKLDTFCGSPPYAAPELFQGKKYDGPE 197
Query: 238 VDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFFHPDVVDLLGKLITADLT 297
VD WSLG++++ +++G PF + E++L G+ P + D +LL K + + +
Sbjct: 198 VDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLILNPS 257
Query: 298 RR 299
+R
Sbjct: 258 KR 259
>Hs9845487 [R] KOG0586 Serine/threonine protein kinase
Length = 745
Score = 150 bits (379), Expect = 3e-36
Identities = 77/242 (31%), Positives = 140/242 (57%), Gaps = 4/242 (1%)
Query: 61 DFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRMLKLVEHP 120
++++++T+G G+F +V L R + G+ A+K++ K Q+ ++ E R++K++ HP
Sbjct: 19 NYRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQL-NSSSLQKLFREVRIMKVLNHP 77
Query: 121 FLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLALEYLHSHN 180
+++++ + + L++VM+Y GGE+F L R A+ ++ A++Y H
Sbjct: 78 NIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKF 137
Query: 181 IIYRDLKPENILLDRNGHIKITDFGFAKEVI--TVTWTLCGTPDYIAPEVITTKPYN-KS 237
I++RDLK EN+LLD + +IKI DFGF+ E T CG+P Y APE+ K Y+
Sbjct: 138 IVHRDLKAENLLLDADMNIKIADFGFSNEFTFGNKLDTFCGSPPYAAPELFQGKKYDGPE 197
Query: 238 VDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFFHPDVVDLLGKLITADLT 297
VD WSLG++++ +++G PF + E++L G+ P + D +LL K + + +
Sbjct: 198 VDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLILNPS 257
Query: 298 RR 299
+R
Sbjct: 258 KR 259
>CE07156 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 392
Score = 150 bits (378), Expect = 4e-36
Identities = 87/277 (31%), Positives = 149/277 (53%), Gaps = 11/277 (3%)
Query: 58 TLHDFQIMRTLGTGSFGRVHLVRSVHN---GRYYAIKVLKKHQIIRMKQ-IEHTNDERRM 113
T+ DF+I++ +G+G++G V VR ++ YA+KV++K ++ + K +EH E ++
Sbjct: 25 TIEDFEILKHIGSGAYGEVAAVRKLNGCDTETIYAMKVMEKRRMSKHKDMVEH---EWKI 81
Query: 114 LKLVEHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLAL 173
L + +PF ++M +FQ R+L VM + GG++ +++ +++ A FY E+ +
Sbjct: 82 LTTIHNPFFMKMSYSFQTKRHLVFVMPFAGGGDMLTMM-ENECLIEESAHFYLCELVEGI 140
Query: 174 EYLHSHNIIYRDLKPENILLDRNGHIKITDFGFAK---EVITVTWTLCGTPDYIAPEVIT 230
YLH +I++RD+K EN+L+ +GH+ ITD+G + + + GT +APEV
Sbjct: 141 GYLHEKHIVHRDVKLENLLIGNDGHLMITDYGLSATGCDAEDAIQGVIGTRHTMAPEVHL 200
Query: 231 TKPYNKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFFHPDVVDLLGK 290
K Y S DWW++GI +M + F + + P P + K
Sbjct: 201 EKKYGTSCDWWAVGITYCDMRSDKAVFDGADSKEYSDSTAKKRPRLPKVLSPRERGFVNK 260
Query: 291 LITADLTRRLGNLQSGPDDIKSHPWFAEVIWEKLVAK 327
LI D T+RLGN G +K+H F V+WE ++AK
Sbjct: 261 LIVRDPTQRLGNGPDGTATVKAHDMFKGVVWEDVLAK 297
>7299437 [R] KOG0586 Serine/threonine protein kinase
Length = 604
Score = 150 bits (378), Expect = 4e-36
Identities = 84/244 (34%), Positives = 139/244 (56%), Gaps = 10/244 (4%)
Query: 62 FQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKK---HQIIRMKQIEHTNDERRMLKLVE 118
++I++TLG G+F +V L + GR AIK++ K + I R K N ++K +
Sbjct: 63 YKIIKTLGKGNFAKVKLAIHLPTGREVAIKLIDKTALNTIARQKLYREVN----IMKKLN 118
Query: 119 HPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLALEYLHS 178
HP ++R+ + R L++VM+Y+ GGELF+ L K+ R A+ ++ A+EY HS
Sbjct: 119 HPNIVRLLQVIESERTLYLVMEYVSGGELFNYLVKNGRMRERDARVLFRQLVSAIEYCHS 178
Query: 179 HNIIYRDLKPENILLDRNGHIKITDFGFAK--EVITVTWTLCGTPDYIAPEVITTKPYN- 235
+I++RDLK EN+LLD+ +KI DFGF+ E T CG+P Y APE+ K Y+
Sbjct: 179 KSIVHRDLKAENLLLDQQMKLKIADFGFSTTFEPKAPLETFCGSPPYAAPELFRGKKYSG 238
Query: 236 KSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFFHPDVVDLLGKLITAD 295
VD WSLG++++ +++G PF + +++L G+ P + + L+ K + +
Sbjct: 239 PEVDSWSLGVVLYTLVSGSLPFDGTNLKELRDRVLRGKYRVPYYVSIECESLIRKFLVLN 298
Query: 296 LTRR 299
T+R
Sbjct: 299 PTQR 302
>7290249 [R] KOG0586 Serine/threonine protein kinase
Length = 1398
Score = 150 bits (378), Expect = 4e-36
Identities = 88/272 (32%), Positives = 143/272 (52%), Gaps = 14/272 (5%)
Query: 62 FQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRMLKLVEHPF 121
+ I RT+G G+F V L R AIK++ K Q+ + ++ E ++K ++HP
Sbjct: 141 YDIERTIGKGNFAVVKLARHRITKNEVAIKIIDKSQLDQTN-LQKVYREVEIMKRLKHPH 199
Query: 122 LIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLALEYLHSHNI 181
+I+++ + +++V +Y GE+F + K R A+F ++ A+EY H I
Sbjct: 200 IIKLYQVMETKNMIYIVSEYASQGEIFDYIAKYGRMSESAARFKFWQIISAVEYCHKKGI 259
Query: 182 IYRDLKPENILLDRNGHIKITDFGFAKEV----ITVTWTLCGTPDYIAPEVITTKPY-NK 236
++RDLK EN+LLD N +IKI DFGF+ + TW CG+P Y APEV K Y
Sbjct: 260 VHRDLKAENLLLDLNMNIKIADFGFSNHFKPGELLATW--CGSPPYAAPEVFEGKQYTGP 317
Query: 237 SVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFFHPDVVDLLGKLITADL 296
+D WSLG++++ ++ G PF T +++L+G P F + L+ +++ +
Sbjct: 318 EIDIWSLGVVLYVLVCGALPFDGSTLQSLRDRVLSGRFRIPFFMSSECEHLIRRMLVLEP 377
Query: 297 TRRLGNLQSGPDDIKSHPWFA-EVIWEKLVAK 327
TRR D IK H W E++ L+AK
Sbjct: 378 TRRY-----TIDQIKRHRWMCPELLEHVLIAK 404
>HsM4505103 [R] KOG0586 Serine/threonine protein kinase
Length = 713
Score = 149 bits (377), Expect = 5e-36
Identities = 78/243 (32%), Positives = 141/243 (57%), Gaps = 6/243 (2%)
Query: 61 DFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRMLKLVEHP 120
++++++T+G G+F +V L R + GR AIK++ K Q+ ++ E R++K++ HP
Sbjct: 55 NYRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQL-NPTSLQKLFREVRIMKILNHP 113
Query: 121 FLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLALEYLHSHN 180
+++++ + + L+++M+Y GG++F L R A+ ++ A++Y H
Sbjct: 114 NIVKLFEVIETQKTLYLIMEYASGGKVFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQKR 173
Query: 181 IIYRDLKPENILLDRNGHIKITDFGFAKEVITVTW---TLCGTPDYIAPEVITTKPYN-K 236
I++RDLK EN+LLD + +IKI DFGF+ E TV T CG+P Y APE+ K Y+
Sbjct: 174 IVHRDLKAENLLLDADMNIKIADFGFSNE-FTVGGKLDTFCGSPPYAAPELFQGKKYDGP 232
Query: 237 SVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFFHPDVVDLLGKLITADL 296
VD WSLG++++ +++G PF + E++L G+ P + D +LL + + +
Sbjct: 233 EVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLNP 292
Query: 297 TRR 299
+R
Sbjct: 293 IKR 295
>At4g14580 [T] KOG0583 Serine/threonine protein kinase
Length = 426
Score = 149 bits (377), Expect = 5e-36
Identities = 85/265 (32%), Positives = 138/265 (52%), Gaps = 7/265 (2%)
Query: 43 ESLLPQRSTVSKGKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMK 102
ES P+ G L +++ R LG+GSF +VH+ RS+ G AIK++ K + I
Sbjct: 2 ESPYPKSPEKITGTVLLGKYELGRRLGSGSFAKVHVARSISTGELVAIKIIDKQKTIDSG 61
Query: 103 QIEHTNDE-RRMLKLVEHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPV 161
E M +L HP ++++ +++V++Y GGELF+ L + R
Sbjct: 62 MEPRIIREIEAMRRLHNHPNVLKIHEVMATKSKIYLVVEYAAGGELFTKLIRFGRLNESA 121
Query: 162 AKFYAAEVTLALEYLHSHNIIYRDLKPENILLDRNGHIKITDFGFA-----KEVITVTWT 216
A+ Y ++ AL + H I +RD+KP+N+LLD+ G++K++DFG + + + T
Sbjct: 122 ARRYFQQLASALSFCHRDGIAHRDVKPQNLLLDKQGNLKVSDFGLSALPEHRSNNGLLHT 181
Query: 217 LCGTPDYIAPEVITTKPYN-KSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVV 275
CGTP Y APEVI + Y+ D WS G+ +F +LAGY PF D + Y KI +
Sbjct: 182 ACGTPAYTAPEVIAQRGYDGAKADAWSCGVFLFVLLAGYVPFDDANIVAMYRKIHKRDYR 241
Query: 276 YPPFFHPDVVDLLGKLITADLTRRL 300
+P + ++ KL+ + R+
Sbjct: 242 FPSWISKPARSIIYKLLDPNPETRM 266
>7299438 [R] KOG0586 Serine/threonine protein kinase
Length = 705
Score = 149 bits (377), Expect = 5e-36
Identities = 83/241 (34%), Positives = 139/241 (57%), Gaps = 4/241 (1%)
Query: 62 FQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRMLKLVEHPF 121
++I++TLG G+F +V L V GR AIKV+ K Q+ + + E +++KL+ HP
Sbjct: 98 YKIIKTLGKGNFAKVKLAIHVPTGREVAIKVIDKTQLNTSAR-QKLYREVKIMKLLNHPN 156
Query: 122 LIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLALEYLHSHNI 181
++R++ + R L++VM+Y GELF L K+ R A+ ++ A++Y HS +
Sbjct: 157 IVRLFQVIESERTLYLVMEYASRGELFDHLVKNGRMRERDARVIFRQLVSAIQYCHSKFV 216
Query: 182 IYRDLKPENILLDRNGHIKITDFGFAK--EVITVTWTLCGTPDYIAPEVITTKPY-NKSV 238
++RDLK EN+LLD++ +IKI DFGF + T CG+P Y APE+ + Y V
Sbjct: 217 VHRDLKAENLLLDQHMNIKIADFGFGNTFDPNAQLETFCGSPPYAAPELFMGRKYAGPEV 276
Query: 239 DWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFFHPDVVDLLGKLITADLTR 298
D WSLG++++ +++G PF T + E++L G+ P + D +L+ K + + +
Sbjct: 277 DAWSLGVVLYTLVSGSLPFDGGTLKELRERVLRGKYRVPYYISMDCENLMRKFLVLNPAK 336
Query: 299 R 299
R
Sbjct: 337 R 337
>YGR092w [R] KOG0605 NDR and related serine/threonine kinases
Length = 572
Score = 149 bits (376), Expect = 6e-36
Identities = 102/378 (26%), Positives = 181/378 (46%), Gaps = 65/378 (17%)
Query: 27 VTVGSQSTDYLLAQQKESLLPQRSTVSKGKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGR 86
+ + + + YL Q++ +L +R K + DF+++ +G G +G+V+L R
Sbjct: 148 IKLNEEWSSYL--QREHQVLRKRRLKPKNR----DFEMITQVGQGGYGQVYLARKKDTKE 201
Query: 87 YYAIKVLKKHQIIRMKQIEHTNDERRMLKLVEHPFLIRMWGTFQDSRNLFMVMDYIEGGE 146
A+K+L K + ++ + +H ER +L +L+++ FQD ++L++ M+++ GG+
Sbjct: 202 VCALKILNKKLLFKLNETKHVLTERDILTTTRSEWLVKLLYAFQDLQSLYLAMEFVPGGD 261
Query: 147 LFSLLRKSQRFPNPVAKFYAAEVTLALEYLHSHNIIYRDLKPENILLDRNGHIKITDFGF 206
+LL ++ + A+FY +E+ A+ LH +RDLKPEN L+D GHIK+TDFG
Sbjct: 262 FRTLLINTRCLKSGHARFYISEMFCAVNALHDLGYTHRDLKPENFLIDAKGHIKLTDFGL 321
Query: 207 A-------------------------------------------KEVITVTWTLCGTPDY 223
A ++ I ++ G+PDY
Sbjct: 322 AAGTISNERIESMKIRLEKIKDLEFPAFTEKSIEDRRKMYNQLREKEINYANSMVGSPDY 381
Query: 224 IAPEVITTKPYNKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVY------- 276
+A EV+ K Y+ +VD+WSLG ++FE L GYTPF + +TY+ + +
Sbjct: 382 MALEVLEGKKYDFTVDYWSLGCMLFESLVGYTPFSGSSTNETYDNLRRWKQTLRRPRQSD 441
Query: 277 -PPFFHPDVVDLLGKLITADLTRRLGNLQSGPDDIKSHPWFAEVIWEKLVAKDIETPYEP 335
F DL+ +LI AD RL + + +K +FA++ + L + + P+ P
Sbjct: 442 GRAAFSDRTWDLITRLI-ADPINRLRSF----EHVKRMSYFADINFSTL--RSMIPPFTP 494
Query: 336 PIAVGVGDSSLFDQYPEE 353
+ D+ FD + E
Sbjct: 495 QLD-SETDAGYFDDFTSE 511
>Hs21361433 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 970
Score = 149 bits (376), Expect = 6e-36
Identities = 78/246 (31%), Positives = 135/246 (54%), Gaps = 4/246 (1%)
Query: 59 LHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRMLKLVE 118
+ DF++ LG GSF V+ S+H+G AIK++ K + + ++ +E ++ ++
Sbjct: 9 IEDFKVGNLLGKGSFAGVYRAESIHSGLEVAIKMIDKKAMYKAGMVQRVQNEVKIHCQLK 68
Query: 119 HPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQR-FPNPVAKFYAAEVTLALEYLH 177
HP ++ ++ F+DS +++V++ GE+ L+ + F A+ + ++ + YLH
Sbjct: 69 HPSILELYNYFEDSNYVYLVLEMCHNGEMNRYLKNRVKPFSENEARHFMHQIITGMLYLH 128
Query: 178 SHNIIYRDLKPENILLDRNGHIKITDFGFAKEVITVT---WTLCGTPDYIAPEVITTKPY 234
SH I++RDL N+LL RN +IKI DFG A ++ +TLCGTP+YI+PE+ T +
Sbjct: 129 SHGILHRDLTLSNLLLTRNMNIKIADFGLATQLKMPHEKHYTLCGTPNYISPEIATRSAH 188
Query: 235 NKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFFHPDVVDLLGKLITA 294
D WSLG + + +L G PF T T K++ + P F + DL+ +L+
Sbjct: 189 GLESDVWSLGCMFYTLLIGRPPFDTDTVKNTLNKVVLADYEMPTFLSIEAKDLIHQLLRR 248
Query: 295 DLTRRL 300
+ RL
Sbjct: 249 NPADRL 254
>HsM7657627 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 970
Score = 149 bits (375), Expect = 8e-36
Identities = 78/246 (31%), Positives = 134/246 (53%), Gaps = 4/246 (1%)
Query: 59 LHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRMLKLVE 118
+ DF++ LG GSF V+ S+H G AIK++ K + + ++ +E ++ ++
Sbjct: 9 IEDFKVGNLLGKGSFAGVYRAESIHTGLEVAIKMIDKKAMYKAGMVQRVKNEVKIHCQLK 68
Query: 119 HPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQR-FPNPVAKFYAAEVTLALEYLH 177
HP ++ ++ F+DS +++V++ GE+ L+ + F A+ + ++ + YLH
Sbjct: 69 HPSILELYNYFEDSNYVYLVLEMCHNGEMNRYLKNRVKPFSENEARHFMHQIITGMLYLH 128
Query: 178 SHNIIYRDLKPENILLDRNGHIKITDFGFAKEVITVT---WTLCGTPDYIAPEVITTKPY 234
SH I++RDL N+LL RN +IKI DFG A ++ +TLCGTP+YI+PE+ T +
Sbjct: 129 SHGILHRDLTLSNLLLTRNMNIKIADFGLATQLKMPHEKHYTLCGTPNYISPEIATRSAH 188
Query: 235 NKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFFHPDVVDLLGKLITA 294
D WSLG + + +L G PF T T K++ + P F + DL+ +L+
Sbjct: 189 GLESDVWSLGCMFYTLLIGRPPFDTDTVKNTLNKVVLADYEMPTFLSIEAKDLIHQLLRR 248
Query: 295 DLTRRL 300
+ RL
Sbjct: 249 NPADRL 254
>Hs4502553 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 370
Score = 149 bits (375), Expect = 8e-36
Identities = 91/268 (33%), Positives = 146/268 (53%), Gaps = 18/268 (6%)
Query: 59 LHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRMLKLVE 118
++DF+ + LGTG+F V L + AIK + K + + K+ N E +L ++
Sbjct: 19 IYDFRDV--LGTGAFSEVILAEDKRTQKLVAIKCIAK-EALEGKEGSMEN-EIAVLHKIK 74
Query: 119 HPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLALEYLHS 178
HP ++ + ++ +L+++M + GGELF + + + A +V A++YLH
Sbjct: 75 HPNIVALDDIYESGGHLYLIMQLVSGGELFDRIVEKGFYTERDASRLIFQVLDAVKYLHD 134
Query: 179 HNIIYRDLKPENIL---LDRNGHIKITDFGFAK--EVITVTWTLCGTPDYIAPEVITTKP 233
I++RDLKPEN+L LD + I I+DFG +K + +V T CGTP Y+APEV+ KP
Sbjct: 135 LGIVHRDLKPENLLYYSLDEDSKIMISDFGLSKMEDPGSVLSTACGTPGYVAPEVLAQKP 194
Query: 234 YNKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFFHPDV----VDLLG 289
Y+K+VD WS+G++ + +L GY PFYD K +E+IL E + + D+ D +
Sbjct: 195 YSKAVDCWSIGVIAYILLCGYPPFYDENDAKLFEQILKAEYEFDSPYWDDISDSAKDFIR 254
Query: 290 KLITADLTRRLGNLQSGPDDIKSHPWFA 317
L+ D +R Q+ HPW A
Sbjct: 255 HLMEKDPEKRFTCEQA-----LQHPWIA 277
>Hs6005850 [D] KOG0615 Serine/threonine protein kinase Chk2 and related
proteins
Length = 543
Score = 148 bits (374), Expect = 1e-35
Identities = 98/279 (35%), Positives = 156/279 (55%), Gaps = 25/279 (8%)
Query: 59 LHDFQIM-RTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIE-----HTNDERR 112
L D IM +TLG+G+ G V L + AIK++ K + E + E
Sbjct: 216 LRDEYIMSKTLGSGACGEVKLAFERKTCKKVAIKIISKRKFAIGSAREADPALNVETEIE 275
Query: 113 MLKLVEHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLA 172
+LK + HP +I++ F D+ + ++V++ +EGGELF + ++R K Y ++ LA
Sbjct: 276 ILKKLNHPCIIKIKNFF-DAEDYYIVLELMEGGELFDKVVGNKRLKEATCKLYFYQMLLA 334
Query: 173 LEYLHSHNIIYRDLKPENILL---DRNGHIKITDFGFAKEV--ITVTWTLCGTPDYIAPE 227
++YLH + II+RDLKPEN+LL + + IKITDFG +K + ++ TLCGTP Y+APE
Sbjct: 335 VQYLHENGIIHRDLKPENVLLSSQEEDCLIKITDFGHSKILGETSLMRTLCGTPTYLAPE 394
Query: 228 VIT---TKPYNKSVDWWSLGILIFEMLAGYTPFYD-VTPMKTYEKILAGEVVYPPFFHPD 283
V+ T YN++VD WSLG+++F L+GY PF + T + ++I +G+ + P +
Sbjct: 395 VLVSVGTAGYNRAVDCWSLGVILFICLSGYPPFSEHRTQVSLKDQITSGKYNFIPEVWAE 454
Query: 284 V----VDLLGKLITADLTRRLGNLQSGPDDIKSHPWFAE 318
V +DL+ KL+ D R ++ HPW +
Sbjct: 455 VSEKALDLVKKLLVVDPKARFTT-----EEALRHPWLQD 488
>7293512 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 483
Score = 148 bits (374), Expect = 1e-35
Identities = 79/199 (39%), Positives = 121/199 (60%), Gaps = 7/199 (3%)
Query: 62 FQIMRTLGTGSFGRVHLVRSVHN-GRYYAIKVLKKHQIIRMKQIEHTNDERRMLKLV-EH 119
++I + G+FG V V S + + YA+KVLKK ++I + DE + K+ H
Sbjct: 159 YRIDHLVAKGAFGVVFKVSSKSDISQCYALKVLKKSKLIEDNSVRQIKDEADIQKVCGHH 218
Query: 120 PFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLALEYLHSH 179
PF+++ +Q+ NL ++ +Y+ GELFS K F + + Y E+ LAL++LH+
Sbjct: 219 PFIVKQIDLWQNRHNLHILSEYVPNGELFS---KITHFSIDLVRLYIGEIALALDFLHNA 275
Query: 180 NIIYRDLKPENILLDRNGHIKITDFGFAK--EVITVTWTLCGTPDYIAPEVITTKPYNKS 237
IIYRD KPENILL HIK+TDFG +K ++ T T+CGT Y+APE++ +PY +
Sbjct: 276 GIIYRDAKPENILLTEQFHIKLTDFGLSKWLKLGANTRTMCGTFKYMAPEILCGEPYGHA 335
Query: 238 VDWWSLGILIFEMLAGYTP 256
VDWW+LG++ +ML +P
Sbjct: 336 VDWWALGVIACQMLTQKSP 354
>At1g50230 [R] KOG0597 Serine-threonine protein kinase FUSED
Length = 269
Score = 147 bits (372), Expect = 2e-35
Identities = 78/222 (35%), Positives = 132/222 (59%), Gaps = 5/222 (2%)
Query: 59 LHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRMLKLVE 118
+ D+ ++ +G GSFGRV+ R + G+ A+K + K Q K I E +L+ ++
Sbjct: 3 VEDYHVIELVGEGSFGRVYKGRRKYTGQTVAMKFIMK-QGKTDKDIHSLRQEIEILRKLK 61
Query: 119 HPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLALEYLHS 178
H +I M +F+++R +V ++ +G ELF +L + P + A ++ AL+YLHS
Sbjct: 62 HENIIEMLDSFENAREFCVVTEFAQG-ELFEILEDDKCLPEEQVQAIAKQLVKALDYLHS 120
Query: 179 HNIIYRDLKPENILLDRNGHIKITDFGFAKEVIT---VTWTLCGTPDYIAPEVITTKPYN 235
+ II+RD+KP+NIL+ +K+ DFGFA+ + T V ++ GTP Y+APE++ +PY+
Sbjct: 121 NRIIHRDMKPQNILIGAGSVVKLCDFGFARAMSTNTVVLRSIKGTPLYMAPELVKEQPYD 180
Query: 236 KSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYP 277
++VD WSLG++++E+ G PFY + I+ V YP
Sbjct: 181 RTVDLWSLGVILYELYVGQPPFYTNSVYALIRHIVKDPVKYP 222
>Hs14728804 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 576
Score = 147 bits (370), Expect = 3e-35
Identities = 76/266 (28%), Positives = 148/266 (55%), Gaps = 21/266 (7%)
Query: 62 FQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRMLKLVEHPF 121
++ R +G G+F V R + YA+K++ K ++ + + + E +++ + HP
Sbjct: 284 YETGRVIGDGNFAVVKECRHRETRQAYAMKIIDKSRLKGKEDM--VDSEILIIQSLSHPN 341
Query: 122 LIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLALEYLHSHNI 181
++++ ++ ++++++Y++GG+LF + +S +FP P A ++ AL ++H +I
Sbjct: 342 IVKLHEVYETDMEIYLILEYVQGGDLFDAIIESVKFPEPDAALMIMDLCKALVHMHDKSI 401
Query: 182 IYRDLKPENILLDRNGH----IKITDFGFAKEVITVTWTLCGTPDYIAPEVITTKPYNKS 237
++RDLKPEN+L+ RN +K+ DFG AK V+ +T+CGTP Y+APE+++ K Y
Sbjct: 402 VHRDLKPENLLVQRNEDKSTTLKLADFGLAKHVVRPIFTVCGTPTYVAPEILSEKGYGLE 461
Query: 238 VDWWSLGILIFEMLAGYTPFYDVTPMKTYEKI-----LAGEVVYPPFF---HPDVVDLLG 289
VD W+ G++++ +L G+ PF +P + +++ L PP++ DL+
Sbjct: 462 VDMWAAGVILYILLCGFPPFR--SPERDQDELFNIIQLGHFEFLPPYWDNISDAAKDLVS 519
Query: 290 KLITADLTRRLGNLQSGPDDIKSHPW 315
+L+ D +R Q + HPW
Sbjct: 520 RLLVVDPKKRYTAHQ-----VLQHPW 540
>Hs13899225 [R] KOG0586 Serine/threonine protein kinase
Length = 688
Score = 147 bits (370), Expect = 3e-35
Identities = 77/242 (31%), Positives = 135/242 (54%), Gaps = 4/242 (1%)
Query: 61 DFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRMLKLVEHP 120
+++++RT+G G+ +V L R + GR AIK++ K Q+ ++ E R++K + HP
Sbjct: 58 NYRLLRTIGKGNSAKVKLARHILTGREVAIKIIDKTQL-NPSSLQKLFREVRIMKGLNHP 116
Query: 121 FLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLALEYLHSHN 180
+++++ + + L++VM+Y GE+F L R A+ ++ A+ Y H N
Sbjct: 117 NIVKLFEVIETEKTLYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAVHYCHQKN 176
Query: 181 IIYRDLKPENILLDRNGHIKITDFGFAKEVI--TVTWTLCGTPDYIAPEVITTKPYN-KS 237
I++RDLK EN+LLD +IKI DFGF+ E + T CG+P Y APE+ K Y+
Sbjct: 177 IVHRDLKAENLLLDAEANIKIADFGFSNEFTLGSKLDTFCGSPPYAAPELFQGKKYDGPE 236
Query: 238 VDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFFHPDVVDLLGKLITADLT 297
VD WSLG++++ +++G PF + E++L G+ P + D +L + + +
Sbjct: 237 VDIWSLGVILYTLVSGSLPFDGHNLKELRERVLRGKYRVPFYMSTDCESILRRFLVLNPA 296
Query: 298 RR 299
+R
Sbjct: 297 KR 298
>YKL101w [D] KOG0588 Serine/threonine protein kinase
Length = 1518
Score = 146 bits (369), Expect = 4e-35
Identities = 90/305 (29%), Positives = 153/305 (49%), Gaps = 44/305 (14%)
Query: 49 RSTVSKGKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQII--------- 99
+S+ K + T+ +++ +TLG GS GRV L +++ G+ AIK++ K +
Sbjct: 68 KSSKRKSRDTVGPWKLGKTLGKGSSGRVRLAKNMETGQLAAIKIVPKKKAFVHCSNNGTV 127
Query: 100 ----------------RMKQIEHTNDERR----------MLKLVEHPFLIRMWGTFQDSR 133
+ EH+N + ++KL+ H ++ ++ +++
Sbjct: 128 PNSYSSSMVTSNVSSPSIASREHSNHSQTNPYGIEREIVIMKLISHTNVMALFEVWENKS 187
Query: 134 NLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLALEYLHSHNIIYRDLKPENILL 193
L++V++Y++GGELF L + P A Y ++ + Y HS NI +RDLKPEN+LL
Sbjct: 188 ELYLVLEYVDGGELFDYLVSKGKLPEREAIHYFKQIVEGVSYCHSFNICHRDLKPENLLL 247
Query: 194 D-RNGHIKITDFGFAKEVI--TVTWTLCGTPDYIAPEVITTKPYNKS-VDWWSLGILIFE 249
D +N IKI DFG A + + T CG+P Y +PE++ +PY+ D WS GI++F
Sbjct: 248 DKKNRRIKIADFGMAALELPNKLLKTSCGSPHYASPEIVMGRPYHGGPSDVWSCGIVLFA 307
Query: 250 MLAGYTPFYDVTPMKTYEKILAGEVVYPPFFHPDVVDLLGKLITADLTRRLGNLQSGPDD 309
+L G+ PF D K K+ +G+ P + DL+ K++ D +R+ +
Sbjct: 308 LLTGHLPFNDDNIKKLLLKVQSGKYQMPSNLSSEARDLISKILVIDPEKRITT-----QE 362
Query: 310 IKSHP 314
I HP
Sbjct: 363 ILKHP 367
>At4g40010 [T] KOG0583 Serine/threonine protein kinase
Length = 350
Score = 146 bits (368), Expect = 5e-35
Identities = 91/266 (34%), Positives = 142/266 (53%), Gaps = 20/266 (7%)
Query: 62 FQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRMLKLVEHPF 121
+ I+R LG+G+FG LVR NG +YA+K +++ +K EH E + ++HP
Sbjct: 4 YDILRDLGSGNFGVAKLVREKANGEFYAVKYIERG----LKIDEHVQREIINHRDLKHPN 59
Query: 122 LIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLALEYLHSHNI 181
+IR F +L +VM+Y GGELF + + RF ++Y ++ + Y H+ I
Sbjct: 60 IIRFKEVFVTPTHLAIVMEYAAGGELFERICNAGRFSEDEGRYYFKQLISGVSYCHAMQI 119
Query: 182 IYRDLKPENILLD--RNGHIKITDFGFAKEVI--TVTWTLCGTPDYIAPEVITTKPYN-K 236
+RDLK EN LLD + H+KI DFG++K + + + GTP Y+APEV++ K YN K
Sbjct: 120 CHRDLKLENTLLDGSPSSHLKICDFGYSKSSVLHSQPKSTVGTPAYVAPEVLSRKEYNGK 179
Query: 237 SVDWWSLGILIFEMLAGYTPFYDVTPMK----TYEKILAGEVVYPPF--FHPDVVDLLGK 290
D WS G+ ++ ML G PF D + T ++IL+ P + + LL +
Sbjct: 180 IADVWSCGVTLYVMLVGAYPFEDPEDPRNIRNTIQRILSVHYTIPDYVRISSECKHLLSR 239
Query: 291 LITADLTRRLGNLQSGPDDIKSHPWF 316
+ AD +R+ +I+ HPWF
Sbjct: 240 IFVADPDKRI-----TVPEIEKHPWF 260
>At3g17510 [T] KOG0583 Serine/threonine protein kinase
Length = 446
Score = 146 bits (368), Expect = 5e-35
Identities = 80/264 (30%), Positives = 138/264 (51%), Gaps = 11/264 (4%)
Query: 59 LHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRMLKLVE 118
L +++ RTLG G+FG+V + +G +A+K++ K +I + E R LK+++
Sbjct: 17 LGKYELGRTLGEGNFGKVKFAKDTVSGHSFAVKIIDKSRIADLNFSLQIKREIRTLKMLK 76
Query: 119 HPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLALEYLHS 178
HP ++R+ + MVM+ + GGELF + + + + ++ + Y HS
Sbjct: 77 HPHIVRLHEVLASKTKINMVMELVTGGELFDRIVSNGKLTETDGRKMFQQLIDGISYCHS 136
Query: 179 HNIIYRDLKPENILLDRNGHIKITDFGFAK-----EVITVTWTLCGTPDYIAPEVITTKP 233
+ +RDLK EN+LLD GHIKITDFG + + T CG+P+Y+APEV+ +
Sbjct: 137 KGVFHRDLKLENVLLDAKGHIKITDFGLSALPQHFRDDGLLHTTCGSPNYVAPEVLANRG 196
Query: 234 YNKSV-DWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFFHPDVVDLLGKLI 292
Y+ + D WS G++++ +L G PF D Y+KI G+ P + P ++ +++
Sbjct: 197 YDGAASDIWSCGVILYVILTGCLPFDDRNLAVLYQKICKGDPPIPRWLSPGARTMIKRML 256
Query: 293 TADLTRRLGNLQSGPDDIKSHPWF 316
+ R+ + IK+ WF
Sbjct: 257 DPNPVTRITVV-----GIKASEWF 275
>ECU07g0360 [D] KOG0580 Serine/threonine protein kinase
Length = 272
Score = 145 bits (367), Expect = 7e-35
Identities = 80/240 (33%), Positives = 129/240 (53%), Gaps = 4/240 (1%)
Query: 57 YTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRMLKL 116
+TL F+I R LG G FG+V L R G A+K++ +I ++ E +
Sbjct: 5 WTLDRFEIGRLLGRGKFGQVWLAREREKGFIVALKIIPIKEIQTVETARQIRREIEIHSN 64
Query: 117 VEHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLR-KSQRFPNPVAKFYAAEVTLALEY 175
++HP ++RM+G F D N++++++Y GE F L + +F Y +V LAL Y
Sbjct: 65 LKHPNILRMYGHFHDKDNIYLILEYAGKGEFFKFLSDRGGKFGEKETSLYIRQVMLALTY 124
Query: 176 LHSHNIIYRDLKPENILLDRNGHIKITDFGFA-KEVITVTWTLCGTPDYIAPEVITTKPY 234
+ N+I+RD+KPEN+LL + +KI DFG+A T CGT +Y+APE++ +
Sbjct: 125 MKECNVIHRDIKPENLLLGSDNQLKIADFGWAVYNADKRRMTFCGTMEYLAPEMVNNDIH 184
Query: 235 NKSVDWWSLGILIFEMLAGYTPF--YDVTPMKTYEKILAGEVVYPPFFHPDVVDLLGKLI 292
+ +D W LGIL +E L G TPF + + Y+KI + + P + D + +L+
Sbjct: 185 DSGIDLWCLGILTYEFLMGKTPFESKNRNMREAYKKINSLKYTIPETISSNASDFISRLL 244
>7304311 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 405
Score = 145 bits (367), Expect = 7e-35
Identities = 78/236 (33%), Positives = 129/236 (54%), Gaps = 23/236 (9%)
Query: 56 KYTLHDFQIMRTLGTGSFGRVHLVRSVHN-GRYYAIKVLKKH-------------QIIRM 101
KY LH LGTG+F V L S + G ++A+K++ K +++R
Sbjct: 30 KYNLHGL-----LGTGAFSEVRLAESKDSPGEHFAVKIIDKKALKGKEESLENEIRVLRR 84
Query: 102 KQIEHTNDERRMLKLVEHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPV 161
H + + + HP ++++ T++D +++VM+ + GGELF + + +
Sbjct: 85 FSANHFDGKCLNGTRLTHPNIVQLLETYEDKSKVYLVMELVTGGELFDRIVEKGSYTEKD 144
Query: 162 AKFYAAEVTLALEYLHSHNIIYRDLKPENILL---DRNGHIKITDFGFAK-EVITVTWTL 217
A ++ A++Y+H +++RDLKPEN+L D + I I+DFG +K E + T
Sbjct: 145 ASHLIRQILEAVDYMHEQGVVHRDLKPENLLYYSPDDDSKIMISDFGLSKMEDSGIMATA 204
Query: 218 CGTPDYIAPEVITTKPYNKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGE 273
CGTP Y+APEV+ KPY K+VD WS+G++ + +L GY PFYD + +IL G+
Sbjct: 205 CGTPGYVAPEVLAQKPYGKAVDVWSIGVISYILLCGYPPFYDENDANLFAQILKGD 260
>At2g38490 [T] KOG0583 Serine/threonine protein kinase
Length = 431
Score = 145 bits (366), Expect = 9e-35
Identities = 91/269 (33%), Positives = 146/269 (53%), Gaps = 19/269 (7%)
Query: 55 GKYTLHDFQIMRTLGTGSFGRVHLVRSVHNG-RYYAIKVLKKHQIIRMKQIEHTNDERRM 113
GKY L + LG+G+F +V+ + NG AIKV++K ++ + H E +
Sbjct: 26 GKYDLG-----KLLGSGAFAKVYQAEDLQNGGESVAIKVVQKKRL-KDGLTAHVKREISV 79
Query: 114 LKLVEHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLAL 173
++ + HP ++ + ++ VM+ +GGELFS + S RF +++ Y ++ A+
Sbjct: 80 MRRLRHPHIVLLSEVLATKTKIYFVMELAKGGELFSRVT-SNRFTESLSRKYFRQLISAV 138
Query: 174 EYLHSHNIIYRDLKPENILLDRNGHIKITDFGFA--KEVI---TVTWTLCGTPDYIAPEV 228
Y H+ + +RDLKPEN+LLD N +K++DFG + KE I + TLCGTP Y+APE+
Sbjct: 139 RYCHARGVFHRDLKPENLLLDENRDLKVSDFGLSAMKEQIHPDGMLHTLCGTPAYVAPEL 198
Query: 229 ITTKPYNKS-VDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFFHPDVVDL 287
+ K Y+ S D WS G+++F + AGY PF D M Y KI + P + D+ L
Sbjct: 199 LLKKGYDGSKADIWSCGVVLFLLNAGYLPFRDPNIMGLYRKIHKAQYKLPDWTSSDLRKL 258
Query: 288 LGKLITADLTRRLGNLQSGPDDIKSHPWF 316
L +L+ + L+ ++I PWF
Sbjct: 259 LRRLLEPN-----PELRITVEEILKDPWF 282
>Hs13569922 [R] KOG0611 Predicted serine/threonine protein kinase
Length = 628
Score = 144 bits (364), Expect = 2e-34
Identities = 84/259 (32%), Positives = 139/259 (53%), Gaps = 10/259 (3%)
Query: 60 HDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRMLKLVEH 119
H ++ + TLG G++G+V R +GR AIK ++K +I + + H E ++ + H
Sbjct: 51 HRYEFLETLGKGTYGKVKKARE-SSGRLVAIKSIRKDKIKDEQDLMHIRREIEIMSSLNH 109
Query: 120 PFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLALEYLHSH 179
P +I + F++S + +VM+Y G+L+ + + Q+ A+ + ++ A+ Y H +
Sbjct: 110 PHIIAIHEVFENSSKIVIVMEYASRGDLYDYISERQQLSEREARHFFRQIVSAVHYCHQN 169
Query: 180 NIIYRDLKPENILLDRNGHIKITDFGFAK--EVITVTWTLCGTPDYIAPEVITTKPY-NK 236
+++RDLK ENILLD NG+IKI DFG + T CG+P Y +PE++ KPY
Sbjct: 170 RVVHRDLKLENILLDANGNIKIADFGLSNLYHQGKFLQTFCGSPLYASPEIVNGKPYTGP 229
Query: 237 SVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFFHPDVVDLLGKLITADL 296
VD WSLG+L++ ++ G PF D K K ++ P D L+ L+ +
Sbjct: 230 EVDSWSLGVLLYILVHGTMPF-DGHDHKILVKQISNGAYREPPKPSDACGLIRWLLMVNP 288
Query: 297 TRRLGNLQSGPDDIKSHPW 315
TRR + +D+ SH W
Sbjct: 289 TRR-----ATLEDVASHWW 302
>CE05780 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 336
Score = 143 bits (360), Expect = 5e-34
Identities = 83/280 (29%), Positives = 138/280 (48%), Gaps = 20/280 (7%)
Query: 62 FQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIR------MKQIEH--------- 106
++I +G G+F VHL R +G A+KV + + +Q+E
Sbjct: 57 YEIGAIIGKGNFSSVHLTRRKEDGTKCALKVRYQSTLQFSFPSKFFQQVEKRAMRGKCFF 116
Query: 107 TNDERRMLKLVEHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYA 166
++E ML L++H +I + F F+V ++ + G+L+ +RK+ R P A
Sbjct: 117 VDNEVEMLSLIQHDHIISIIDAFSTENQYFIVFEHAQYGDLYETIRKNGRIEEPDAAIIT 176
Query: 167 AEVTLALEYLHSHNIIYRDLKPENILLDRNGHIKITDFGFAKEVITVTWTLCGTPDYIAP 226
+V AL YLH N+++RD+KPEN+LL +K+ DFG A ++ + +CGTP Y AP
Sbjct: 177 LQVASALNYLHERNVVHRDVKPENLLLVDKFSVKLCDFGLACHILGPLYRICGTPTYCAP 236
Query: 227 EVITTKPYNKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFFHPD--V 284
EV+ Y+ D WSLG++++ ML GY PF + ++ I+ + P P+
Sbjct: 237 EVLRETGYSTRCDIWSLGVVLYVMLVGYAPFRAPDQTRLFKLIMQAK---PNLDMPEWKG 293
Query: 285 VDLLGKLITADLTRRLGNLQSGPDDIKSHPWFAEVIWEKL 324
+ L K + + L + + I +HPW A E +
Sbjct: 294 ISLKAKDLVSRLMNKTEERRPLASQIMAHPWIAPYTMENI 333
>CE26793_1 [R] KOG0611 Predicted serine/threonine protein kinase
Length = 795
Score = 143 bits (360), Expect = 5e-34
Identities = 88/269 (32%), Positives = 139/269 (50%), Gaps = 15/269 (5%)
Query: 53 SKGKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERR 112
S K H F+I + LG+G++G+V L R A+K++KK I + E R
Sbjct: 66 SPTKKEKHRFEITKKLGSGTYGKVSLAYDHKFDREVAVKLIKKSAIESKADLVRIRREIR 125
Query: 113 MLKLVEHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLA 172
++ + HP +I+++ F++ + +VM+Y GGEL+ + + P A+ ++T A
Sbjct: 126 IMSALNHPNIIQIYEVFENKDKIILVMEYSSGGELYDYVSRCGSLPEAEARRIFRQITSA 185
Query: 173 LEYLHSHNIIYRDLKPENILLDRNGHIKITDFGFA-----KEVITVTWTLCGTPDYIAPE 227
+ Y H H + +RDLK ENILLD+N + KI DFG + K ++T T CG+P Y +PE
Sbjct: 186 VLYCHKHRVAHRDLKLENILLDQNNNAKIADFGLSNYFADKNLLT---TFCGSPLYASPE 242
Query: 228 VITTKPY-NKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFFHPDVVD 286
+I PY VD WSLGIL++ ++ G PF + +I G +F P+
Sbjct: 243 IINGTPYKGPEVDCWSLGILLYTLVYGSMPFDGRDFNRMVRQIKRG-----AYFEPETPS 297
Query: 287 LLGKLITADLTRRLGNLQSGPDDIKSHPW 315
LI ++ R ++ DI SH W
Sbjct: 298 TASMLI-RNMLRVNPERRATIFDIASHWW 325
>7296450 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 769
Score = 142 bits (359), Expect = 6e-34
Identities = 75/239 (31%), Positives = 124/239 (51%), Gaps = 4/239 (1%)
Query: 58 TLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRMLKLV 117
T+ D+++ LG G F V+ R +H + AIK++ K I E + +
Sbjct: 10 TIEDYEVQHLLGKGGFATVYKARCLHTHQDVAIKMIDKKLIQGTGLTNRVRQEVEIHSRL 69
Query: 118 EHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQR-FPNPVAKFYAAEVTLALEYL 176
+HP +++++ FQD+ +++V++ GEL + R F A +V L YL
Sbjct: 70 KHPSVLQLYTFFQDANYVYLVLELAHNGELHRYMNHIARPFTETEAASILKQVVAGLLYL 129
Query: 177 HSHNIIYRDLKPENILLDRNGHIKITDFGFAKEVITVT---WTLCGTPDYIAPEVITTKP 233
HSHNI++RD+ N+LL R H+KI DFG A ++ T+CGTP+YI+PEV++
Sbjct: 130 HSHNIMHRDISLSNLLLSREMHVKIADFGLATQLKRPDERHMTMCGTPNYISPEVVSRTS 189
Query: 234 YNKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFFHPDVVDLLGKLI 292
+ D WS+G +++ +L G PF T K++ E + P + DL+ KL+
Sbjct: 190 HGLPADVWSVGCMLYTLLVGRPPFETDAVQSTLNKVVMSEYIMPAHLSYEAQDLINKLL 248
>Hs14916455 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 385
Score = 142 bits (358), Expect = 8e-34
Identities = 91/261 (34%), Positives = 131/261 (49%), Gaps = 11/261 (4%)
Query: 62 FQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDERRMLKLVEHPF 121
+ I +GTGSF RV V + +AIKV++ + + E E +L+ V H +
Sbjct: 63 YDIKALIGTGSFSRVVRVEQKTTKKPFAIKVMETRE---REGREACVSELSVLRRVSHRY 119
Query: 122 LIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLALEYLHSHNI 181
++++ F+ ++MVM+ GGELF L F A V + YLH+ I
Sbjct: 120 IVQLMEIFETEDQVYMVMELATGGELFDRLIAQGSFTERDAVRILQMVADGIRYLHALQI 179
Query: 182 IYRDLKPENILLDRNGH---IKITDFGFA----KEVITVTWTLCGTPDYIAPEVITTKPY 234
+R+LKPEN+L G I ITDFG A K TLCGTP+YIAPEV+ KPY
Sbjct: 180 THRNLKPENLLYYHPGEESKILITDFGLAYSGKKSGDWTMKTLCGTPEYIAPEVLLRKPY 239
Query: 235 NKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFFHPDVVDLLGKLITA 294
+VD W+LG++ + +L+G+ PF D + + Y KIL G+ Y P + L I
Sbjct: 240 TSAVDMWALGVITYALLSGFLPFDDESQTRLYRKILKGKYNYTGEPWPSISHLAKDFIDK 299
Query: 295 DLTRRLGNLQSGPDDIKSHPW 315
L G+ S + HPW
Sbjct: 300 LLILEAGHRMSAGQAL-DHPW 319
>Hs14141724 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 499
Score = 142 bits (358), Expect = 8e-34
Identities = 79/279 (28%), Positives = 145/279 (51%), Gaps = 17/279 (6%)
Query: 50 STVSKGKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTND 109
ST + ++T ++Q+ LG G+F V + G+ YA K++ ++ + +
Sbjct: 3 STTTCTRFT-DEYQLFEELGKGAFSVVRRCMKIPTGQGYAAKIINTKKL-SARDHQKLER 60
Query: 110 ERRMLKLVEHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEV 169
E R+ +L++HP ++R+ + + ++V D + GGELF + + + A ++
Sbjct: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
Query: 170 TLALEYLHSHNIIYRDLKPENILL---DRNGHIKITDFGFAKEVI---TVTWTLCGTPDY 223
++ + H + I++RDLKPEN+LL + +K+ DFG A EV + GTP Y
Sbjct: 121 LESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
Query: 224 IAPEVITTKPYNKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYP----PF 279
++PEV+ PY K VD W+ G++++ +L GY PF+D + Y++I AG +P
Sbjct: 181 LSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT 240
Query: 280 FHPDVVDLLGKLITADLTRRLGNLQSGPDDIKSHPWFAE 318
P+ DL+ K++T + +R+ + HPW +
Sbjct: 241 VTPEAKDLINKMLTINPAKRI-----TASEALKHPWICQ 274
>7298652 [D] KOG0615 Serine/threonine protein kinase Chk2 and related
proteins
Length = 459
Score = 142 bits (357), Expect = 1e-33
Identities = 85/278 (30%), Positives = 148/278 (52%), Gaps = 29/278 (10%)
Query: 62 FQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTND------ERRMLK 115
+ + R LG+G++G V LV + +A+K++KK+ + + + +D E +++K
Sbjct: 157 YYVNRKLGSGAYGLVRLVYDTRTCQQFAMKIVKKNMLSGARPSTNFSDPDRVLNEAKIMK 216
Query: 116 LVEHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLALEY 175
+ HP ++RM +++MV++++ GG+L + + ++ ++K Y ++ A++Y
Sbjct: 217 NLSHPCVVRMHDIVDKPDSVYMVLEFMRGGDLLNRIISNKLLSEDISKLYFYQMCHAVKY 276
Query: 176 LHSHNIIYRDLKPENILLDRNGH---IKITDFGFAKEV--ITVTWTLCGTPDYIAPEVIT 230
LH I +RDLKP+N+LL+ N +K++DFG +K V +V TLCGTP Y+APEV+
Sbjct: 277 LHDRGITHRDLKPDNVLLETNDEETLLKVSDFGLSKFVQKDSVMRTLCGTPLYVAPEVLI 336
Query: 231 T---KPYNKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFFHPDVVD- 286
T + Y K VD WSLG+++F L+G PF D ++I G Y HP
Sbjct: 337 TGGREAYTKKVDIWSLGVVLFTCLSGTLPFSDEYGTPAAQQIKKGRFAYG---HPSWKSV 393
Query: 287 ------LLGKLITADLTRRLGNLQSGPDDIKSHPWFAE 318
L+ +++ D RR DD+ W +
Sbjct: 394 SQRAKLLINQMLIVDPERR-----PSIDDVLQSSWLRD 426
>Hs14770402 [R] KOG0586 Serine/threonine protein kinase
Length = 926
Score = 141 bits (356), Expect = 1e-33
Identities = 92/308 (29%), Positives = 150/308 (47%), Gaps = 35/308 (11%)
Query: 52 VSKGKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDER 111
+ +G + + I TLG G+F V L R AIK++ K Q+ + +E E
Sbjct: 10 LQRGPVRVGFYDIEGTLGKGNFAVVKLGRHRITKTEVAIKIIDKSQLDAVN-LEKIYREV 68
Query: 112 RMLKLVEHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTL 171
+++K+++HP +I+++ + L++V +Y + GE+F L R A+ ++
Sbjct: 69 QIMKMLDHPHIIKLYQVMETKSMLYLVTEYAKNGEIFDYLANHGRLNESEARRKFWQILS 128
Query: 172 ALEYLHSHNIIYRDLKPENILLDRNGHIKITDFGFA----KEVITVTWTLCGTPDYIAPE 227
A++Y H I++RDLK EN+LLD N +IKI DFGF + TW CG+P Y APE
Sbjct: 129 AVDYCHGRKIVHRDLKAENLLLDNNMNIKIADFGFGNFFKSGELLATW--CGSPPYAAPE 186
Query: 228 VITTKPY-NKSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFFHPDVVD 286
V + Y +D WS+G++++ ++ G PF T +++L G P F D
Sbjct: 187 VFEGQQYEGPQLDIWSMGVVLYVLVCGALPFDGPTLPILRQRVLEGRFRIPYFMSEDCEH 246
Query: 287 LLGKLITADLTRRLGNLQSGPDDIKSHPWFAEVIWEKLVAKDIETPYEPPIAVGVGDSSL 346
L+ +++ D ++RL Q IK H W IE P + P+
Sbjct: 247 LIRRMLVLDPSKRLTIAQ-----IKEHKWML-----------IEVPVQRPVL-------- 282
Query: 347 FDQYPEEQ 354
YP+EQ
Sbjct: 283 ---YPQEQ 287
>At3g23000 [T] KOG0583 Serine/threonine protein kinase
Length = 429
Score = 141 bits (356), Expect = 1e-33
Identities = 78/251 (31%), Positives = 134/251 (53%), Gaps = 6/251 (2%)
Query: 56 KYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKHQIIRMKQIEHTNDE-RRML 114
K L +++ R LG+GSF +VHL RS+ + A+K+++K + I E M
Sbjct: 19 KILLGKYELGRRLGSGSFAKVHLARSIESDELVAVKIIEKKKTIESGMEPRIIREIDAMR 78
Query: 115 KLVEHPFLIRMWGTFQDSRNLFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVTLALE 174
+L HP ++++ +++VM+ GGELFS + + R P A+ Y ++ AL
Sbjct: 79 RLRHHPNILKIHEVMATKSKIYLVMELASGGELFSKVLRRGRLPESTARRYFQQLASALR 138
Query: 175 YLHSHNIIYRDLKPENILLDRNGHIKITDFGFA--KEVIT--VTWTLCGTPDYIAPEVIT 230
+ H + +RD+KP+N+LLD G++K++DFG + E + + T CGTP Y APEVI+
Sbjct: 139 FSHQDGVAHRDVKPQNLLLDEQGNLKVSDFGLSALPEHLQNGLLHTACGTPAYTAPEVIS 198
Query: 231 TKPYN-KSVDWWSLGILIFEMLAGYTPFYDVTPMKTYEKILAGEVVYPPFFHPDVVDLLG 289
+ Y+ D WS G+++F +L G PF D Y KI + +P + ++
Sbjct: 199 RRGYDGAKADAWSCGVILFVLLVGDVPFDDSNIAAMYRKIHRRDYRFPSWISKQAKSIIY 258
Query: 290 KLITADLTRRL 300
+++ + R+
Sbjct: 259 QMLDPNPVTRM 269
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.322 0.140 0.428
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,151,923
Number of Sequences: 60738
Number of extensions: 1025922
Number of successful extensions: 7711
Number of sequences better than 1.0e-05: 1804
Number of HSP's better than 0.0 without gapping: 673
Number of HSP's successfully gapped in prelim test: 1131
Number of HSP's that attempted gapping in prelim test: 3508
Number of HSP's gapped (non-prelim): 2026
length of query: 372
length of database: 30,389,216
effective HSP length: 108
effective length of query: 264
effective length of database: 23,829,512
effective search space: 6290991168
effective search space used: 6290991168
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)