ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIV0935 good M KOG2571 Cell wall/membrane/envelope biogenesis Chitin synthase/hyaluronan synthase (glycosyltransferases)
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIV0935 310193 307440 -918
(918 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YBR038w [M] KOG2571 Chitin synthase/hyaluronan synthase (glycosy... 1246 0.0
SPAC13G6.12c [M] KOG2571 Chitin synthase/hyaluronan synthase (gl... 671 0.0
YNL192w [M] KOG2571 Chitin synthase/hyaluronan synthase (glycosy... 536 e-152
SPBC1709.01 [M] KOG2571 Chitin synthase/hyaluronan synthase (gly... 444 e-124
7296513 [M] KOG2571 Chitin synthase/hyaluronan synthase (glycosy... 79 4e-14
CE10722 [M] KOG2571 Chitin synthase/hyaluronan synthase (glycosy... 76 2e-13
CE06511 [M] KOG2571 Chitin synthase/hyaluronan synthase (glycosy... 76 2e-13
YBR023c [M] KOG2571 Chitin synthase/hyaluronan synthase (glycosy... 66 3e-10
Hs20302153 [M] KOG2571 Chitin synthase/hyaluronan synthase (glyc... 54 1e-06
>YBR038w [M] KOG2571 Chitin synthase/hyaluronan synthase
(glycosyltransferases)
Length = 963
Score = 1246 bits (3225), Expect = 0.0
Identities = 626/971 (64%), Positives = 742/971 (75%), Gaps = 75/971 (7%)
Query: 1 MTRNPFMAEDEEPPVIRSPQRAAMRXXXXXXXXXXXXXXXXR---------------FQG 45
MTRNPFM E P SP R FQG
Sbjct: 1 MTRNPFMVE----PSNGSPNRRGASNLSKFYANANSNSRWANPSEESLEDSYDQSNVFQG 56
Query: 46 FPAVDSNPSSPSKAAARYSPQKMNNTLI--DSVHNSPLPRNRYQANLQESPRRMNHALID 103
PA SPS+AA RYSP + + T DS HNSP+ NRY ANLQESP+R A+I
Sbjct: 57 LPA------SPSRAALRYSPDRRHRTQFYRDSAHNSPVAPNRYAANLQESPKRAGEAVIH 110
Query: 104 VESNDGESLY---------DIYTNSPTK--PGPLF--QRLTSNETEYTYDSRKISG---- 146
+ ++G +LY D Y SP + LF RL S ++YT + +
Sbjct: 111 L--SEGSNLYPRDNADLPVDPYHLSPQQQPSNNLFGSGRLYSQSSKYTMSTTSTTAPSLA 168
Query: 147 ------------------ESTVYSGDTFGETKFELNHPKTQTYKKRGLSEVRRH-----P 183
+ST++S DTF ETKFELNHP Q Y +R SE +R P
Sbjct: 169 EADDEKEKYLTSTTSYDDQSTIFSADTFNETKFELNHPTRQQYVRRANSESKRRMVSDLP 228
Query: 184 PAFKQRRILKLDNPIPSGLRDIIPKRDSPEFTEMRYTACTSDPDTFVEDGYNLRMAEMNR 243
P K++ +LKLDNPIP GL D +P+R+SPEFTEMRYTACT +PD F+ +GY LR AEMNR
Sbjct: 229 PPSKKKALLKLDNPIPKGLLDTLPRRNSPEFTEMRYTACTVEPDDFLREGYTLRFAEMNR 288
Query: 244 ECQITICVTMYNEDKFALARTLHSIQKNVAHLCKRHKSNVWGPTGWKTVQIIIISDGRSR 303
ECQI IC+TMYNEDK++LART+HSI KNVAHLCKR KS+VWGP GWK V +I+ISDGR++
Sbjct: 289 ECQIAICITMYNEDKYSLARTIHSIMKNVAHLCKREKSHVWGPNGWKKVSVILISDGRAK 348
Query: 304 INQGSLDYLAAIGVYQEDMAKSTVNGEPVKAHIFELTTQVSIDEELNYRSEGTVPCQMVF 363
+NQGSLDYLAA+GVYQEDMAK++VNG+PVKAHIFELTTQVSI+ +L+Y S+ VP Q+VF
Sbjct: 349 VNQGSLDYLAALGVYQEDMAKASVNGDPVKAHIFELTTQVSINADLDYVSKDIVPVQLVF 408
Query: 364 CLKEENQKKINSHRWLFNAFCPILDPTVVTLVDVGTKLNSTAVYHLWKVFDMDSNVAGAA 423
CLKEEN+KKINSHRWLFNAFCP+L PTVVTLVDVGT+LN+TA+Y LWKVFDMDSNVAGAA
Sbjct: 409 CLKEENKKKINSHRWLFNAFCPVLQPTVVTLVDVGTRLNNTAIYRLWKVFDMDSNVAGAA 468
Query: 424 GQIKTMKGKFDMKLLNPLVAAQNFEYKMSNILDKPLESVFGYITVLPGALSAYRYRALKN 483
GQIKTMKGK+ +KL NPLVA+QNFEYK+SNILDKPLESVFGYI+VLPGALSAYRYRALKN
Sbjct: 469 GQIKTMKGKWGLKLFNPLVASQNFEYKISNILDKPLESVFGYISVLPGALSAYRYRALKN 528
Query: 484 NDDGTGPLHSYFLGETQEGRDHDVFTANMYLAEDRILCWELVAKRDEAWVLKYVKEATGE 543
++DGTGPL SYFLGETQEGRDHDVFTANMYLAEDRILCWELVAKRD WVLKYVKEATGE
Sbjct: 529 HEDGTGPLRSYFLGETQEGRDHDVFTANMYLAEDRILCWELVAKRDAKWVLKYVKEATGE 588
Query: 544 TDVPEEPPEFISQRRRWLNGAMFSALYAQIHFHQIWKTRHSTTRKFFFHIEFLYQLVQMI 603
TDVPE+ EFISQRRRWLNGAMF+A+YAQ+HF+QIWKT+HS RKFF H+EFLYQ +QM+
Sbjct: 589 TDVPEDVSEFISQRRRWLNGAMFAAIYAQLHFYQIWKTKHSVVRKFFLHVEFLYQFIQML 648
Query: 604 FSWFSISNFFLTFYYLAGSMNSIIPHGDVLFTFFKYLLICNLCALFIISMGNRPQGANHL 663
FSWFSI+NF LTFYYLAGSMN +I HG+ LF FFKYL+ C+L +LFIISMGNRPQGA HL
Sbjct: 649 FSWFSIANFVLTFYYLAGSMNLVIKHGEALFIFFKYLIFCDLASLFIISMGNRPQGAKHL 708
Query: 664 FISSMVMLTICSTYALVCGLVFAIKTLDDGTEEHSVFVNIVVSLLSTYGLYAFTSLLYLD 723
FI+SMV+L+IC+TY+L+CG VFA K+L GTE H +FV+IV+SLLSTYGLY F+SL+YLD
Sbjct: 709 FITSMVILSICATYSLICGFVFAFKSLASGTESHKIFVDIVISLLSTYGLYFFSSLMYLD 768
Query: 724 PWHIFTSSVQYLLMLPSFICTLQIFAFCNTHDVSWGTKGSTEAAKPIPSAEVIQGPDGIT 783
PWH+FTSS+QY L LP+F CTLQIFAFCNTHDVSWGTKGST+ +K + A V+QGPDG
Sbjct: 769 PWHMFTSSIQYFLTLPAFTCTLQIFAFCNTHDVSWGTKGSTQESKQLSKAIVVQGPDGKQ 828
Query: 784 IVTDQWPQDIDNKYQELKSRLKEKEMVEEKVDLTQKQNDYYRDIRTRIVMVWMLSNLILM 843
IV WPQ++D K+ E+KSRLKE E E + Q +NDYYRDIRTRIVM+WMLSNLIL+
Sbjct: 829 IVETDWPQEVDKKFLEIKSRLKEPEFEESSGNEKQSKNDYYRDIRTRIVMIWMLSNLILI 888
Query: 844 MIITQIYEPEETVNNIYLKFILWSVAALAAFRATGSIIFLLMKYLRLLISWKHKAEDSGS 903
M I Q++ P++T +N YL FILWSVAALAAFR GS+ FL MKYLR+++S+++K E SGS
Sbjct: 889 MSIIQVFTPQDT-DNGYLIFILWSVAALAAFRVVGSMAFLFMKYLRIIVSYRNKVEGSGS 947
Query: 904 -----LNLPSV 909
L+LP+V
Sbjct: 948 WEVSKLDLPNV 958
>SPAC13G6.12c [M] KOG2571 Chitin synthase/hyaluronan synthase
(glycosyltransferases)
Length = 859
Score = 671 bits (1731), Expect = 0.0
Identities = 338/722 (46%), Positives = 459/722 (62%), Gaps = 27/722 (3%)
Query: 192 LKLDNPIPSGLRDIIPKRDSPEFTEMRYTACTSDPDTFVEDGYNLR--MAEMNRECQITI 249
L LD PIP L +P++ EF MRY+A T DP F + + LR + R+ +I I
Sbjct: 133 LILDCPIPKKLLVTLPQQTEREFAYMRYSAATCDPQDFSKSLFTLRQPLFFQPRKTEICI 192
Query: 250 CVTMYNEDKFALARTLHSIQKNVAHLCKRHKSNVWGPTGWKTVQIIIISDGRSRINQGSL 309
+TMYNED+ ART+HS+ KN++HLC R S VWG WK V + IISDGR++I+ +L
Sbjct: 193 AITMYNEDEVLFARTMHSVMKNISHLCTRKNSQVWGKDAWKKVVVCIISDGRTKIHPRTL 252
Query: 310 DYLAAIGVYQEDMAKSTVNGEPVKAHIFELTTQVSIDEELNYRSE--GTVPCQMVFCLKE 367
YLAAIGVYQ+ +AK+ VN + VKAHI+E TTQ+SID L ++ G VP QM+FCLKE
Sbjct: 253 AYLAAIGVYQDGIAKNQVNDKEVKAHIYEYTTQLSIDPNLKFKGSDRGIVPVQMIFCLKE 312
Query: 368 ENQKKINSHRWLFNAFCPILDPTVVTLVDVGTKLNSTAVYHLWKVFDMDSNVAGAAGQIK 427
+NQKK+NSH W F AFCPIL P V L+D GT+ ++YHLWK FD++ VAGA G+I
Sbjct: 313 KNQKKLNSHLWFFQAFCPILKPEVCILLDAGTRPGDQSIYHLWKSFDLNPQVAGACGEIV 372
Query: 428 TMKGKFDMKLLNPLVAAQNFEYKMSNILDKPLESVFGYITVLPGALSAYRYRALKNNDDG 487
MKGK L+NPLVA QNFEYKMSNILDKP+ESVFG+I+VLPGA SAYR+ AL+N+ G
Sbjct: 373 VMKGKLGSGLINPLVATQNFEYKMSNILDKPVESVFGFISVLPGAFSAYRFEALQNDSQG 432
Query: 488 TGPLHSYFLGETQEGRDHDVFTANMYLAEDRILCWELVAKRDEAWVLKYVKEATGETDVP 547
GPL SYF GE Q +F ANMYLAEDRILC+ELV+K++EAW+L YVK A +TDVP
Sbjct: 433 NGPLASYFKGELQNTGKSGIFEANMYLAEDRILCFELVSKKNEAWILHYVKSAYADTDVP 492
Query: 548 EEPPEFISQRRRWLNGAMFSALYAQIHFHQIWKTRHSTTRKFFFHIEFLYQLVQMIFSWF 607
+ PEF+ QRRRWLNG+ F+A YA H+++ ++T H+ +RKF IEF+YQL ++F WF
Sbjct: 493 DRIPEFVLQRRRWLNGSFFAAAYAICHYYRFFRTSHTISRKFMLSIEFIYQLATIVFGWF 552
Query: 608 SISNFFLTFYYLAGSMNSIIPH---GDVLFTFFKYLLICNLCALFIISMGNRPQGANHLF 664
+I NFF+ FY L S+ S + G++LF ++ L F++++GNRP G+ + +
Sbjct: 553 NIGNFFIIFYILTSSLASTSANFLPGEILFRIAIWIYASLLVTCFVLALGNRPHGSPNFY 612
Query: 665 ISSMVMLTICSTYALVCGLVFAIKTLDDGTEEHS--------------VFVNIVVSLLST 710
+S ++M +I Y L C A + + D S VF+NIV+SL ST
Sbjct: 613 LSMVIMYSILMGYLLFCSGWIAYRAISDAIHNASSTSSSYTSALLNSNVFINIVISLSST 672
Query: 711 YGLYAFTSLLYLDPWHIFTSSVQYLLMLPSFICTLQIFAFCNTHDVSWGTKGSTEAAKPI 770
YG+Y S++ DPWH+FTS VQY+ + + L ++AFCNTHDVSWGTKG +
Sbjct: 673 YGMYLVVSIISFDPWHMFTSFVQYIFLSIMYTNVLNVYAFCNTHDVSWGTKGDHFTNNDL 732
Query: 771 PSAEVIQGPDGITIVTDQWPQDIDNKYQELKSRLKEKEMVEEKVDLTQ-KQNDYYRDIRT 829
A ++Q + I DID KY++ L + + +Q D+Y++ RT
Sbjct: 733 GVARLLQKGADVEIAIPTNQSDIDAKYEDAVKLLASPSLEFNSPIINHGEQEDFYKNFRT 792
Query: 830 RIVMVWMLSNLILMMIITQI-----YEPEETVNNIYLKFILWSVAALAAFRATGSIIFLL 884
+V+ W+LSNL L+ I+ I + YL F+LWSV A + FR G I +L
Sbjct: 793 YVVLTWILSNLFLVGIVLSIPKINGISISNNETSAYLSFLLWSVVAFSVFRFIGCIFYLF 852
Query: 885 MK 886
++
Sbjct: 853 IR 854
>YNL192w [M] KOG2571 Chitin synthase/hyaluronan synthase
(glycosyltransferases)
Length = 1131
Score = 536 bits (1382), Expect = e-152
Identities = 286/727 (39%), Positives = 428/727 (58%), Gaps = 62/727 (8%)
Query: 213 EFTEMRYTACTSDPDTFVEDGYNLRMAEM--NRECQITICVTMYNEDKFALARTLHSIQK 270
EF MRY A T +P+ E + +R + RE ++ + VTMYNED L RTL I
Sbjct: 412 EFKFMRYQAVTCEPNQLAEKNFTVRQLKYLTPRETELMLVVTMYNEDHILLGRTLKGIMD 471
Query: 271 NVAHLCKRHKSNVWGPTGWKTVQIIIISDGRSRINQGSLDYLAAIGVYQEDMAKSTVNGE 330
NV ++ K+ S+ WGP WK + + IISDGRS+IN+ SL L+++G YQ+ AK +N +
Sbjct: 472 NVKYMVKKKNSSTWGPDAWKKIVVCIISDGRSKINERSLALLSSLGCYQDGFAKDEINEK 531
Query: 331 PVKAHIFELTTQVSI----DEELNYR-SEGTVPCQMVFCLKEENQKKINSHRWLFNAFCP 385
V H++E TT ++I + E++ ++GTVP Q++FCLKE+NQKKINSHRW F F
Sbjct: 532 KVAMHVYEHTTMINITNISESEVSLECNQGTVPIQLLFCLKEQNQKKINSHRWAFEGFAE 591
Query: 386 ILDPTVVTLVDVGTKLNSTAVYHLWKVFDMDSNVAGAAGQIKTMKGKFDMKLLNPLVAAQ 445
+L P +VTL+D GT ++Y LW+ F + NV GA G+I+T GK +KLLNPLVA+Q
Sbjct: 592 LLRPNIVTLLDAGTMPGKDSIYQLWREF-RNPNVGGACGEIRTDLGKRFVKLLNPLVASQ 650
Query: 446 NFEYKMSNILDKPLESVFGYITVLPGALSAYRYRALKNNDDGTGPLHSYFLGETQEGRDH 505
NFEYKMSNILDK ES FG+ITVLPGA SAYR+ A++ PL YF GE E
Sbjct: 651 NFEYKMSNILDKTTESNFGFITVLPGAFSAYRFEAVRGQ-----PLQKYFYGEIMENEGF 705
Query: 506 DVFTANMYLAEDRILCWELVAKRDEAWVLKYVKEATGETDVPEEPPEFISQRRRWLNGAM 565
F++NMYLAEDRILC+E+V K++ W+LKY + + TDVPE PEFI QRRRWLNG+
Sbjct: 706 HFFSSNMYLAEDRILCFEVVTKKNCNWILKYCRSSYASTDVPERVPEFILQRRRWLNGSF 765
Query: 566 FSALYAQIHFHQIWKTRHSTTRKFFFHIEFLYQLVQMIFSWFSISNFFLTFYYLAGSMNS 625
F+++Y+ HF+++W + H+ RK +EF Y + SWFS+S+FFL F L S+ +
Sbjct: 766 FASVYSFCHFYRVWSSGHNIGRKLLLTVEFFYLFFNTLISWFSLSSFFLFFRILTVSI-A 824
Query: 626 IIPHG--DVLFTFFKYLL-ICNLCALFIISMGNRPQGANHLFISSMVMLTICSTYALVCG 682
+ H +VL F +L IC L + FI+S+GN+P+ ++ + V+ + Y + C
Sbjct: 825 LAYHSAFNVLSVIFLWLYGICTL-STFILSLGNKPKSTEKFYVLTCVIFAVMMIYMIFCS 883
Query: 683 LVFAIKTLD----------DGTEEHSVFVNIVVSLLSTYGLYAFTSLLYLDPWHIFTSSV 732
+ ++K+ +G F +IV+SL STY LY +S++YL PWH+ TS +
Sbjct: 884 IFMSVKSFQNILKNDTISFEGLITTEAFRDIVISLGSTYCLYLISSIIYLQPWHMLTSFI 943
Query: 733 QYLLMLPSFICTLQIFAFCNTHDVSWGTKGSTEAAKPIPSAEVIQGPDG-----ITIVTD 787
QY+L+ PS+I L I+AFCN HD+SWGTKG A P ++ DG + + +
Sbjct: 944 QYILLSPSYINVLNIYAFCNVHDLSWGTKG----AMANPLGKINTTEDGTFKMEVLVSSS 999
Query: 788 QWPQDIDNKYQELKSRLKEKEMVEEKVDLTQKQNDYYRDIRTRIVMVWMLSNLILMMIIT 847
+ + D + L + E + +K+ YY ++R+ +++ W+++N I++ ++
Sbjct: 1000 EIQANYDKYLKVLNDFDPKSESRPTEPSYDEKKTGYYANVRSLVIIFWVITNFIIVAVVL 1059
Query: 848 QI-----------YEPEETVN--------------NIYLKFILWSVAALAAFRATGSIIF 882
+ ++T+ +IY ILW VA A R G I+
Sbjct: 1060 ETGGIADYIAMKSISTDDTLETAKKAEIPLMTSKASIYFNVILWLVALSALIRFIGCSIY 1119
Query: 883 LLMKYLR 889
+++++ +
Sbjct: 1120 MIVRFFK 1126
>SPBC1709.01 [M] KOG2571 Chitin synthase/hyaluronan synthase
(glycosyltransferases)
Length = 926
Score = 444 bits (1142), Expect = e-124
Identities = 235/721 (32%), Positives = 389/721 (53%), Gaps = 24/721 (3%)
Query: 192 LKLDNPIPSGLRDIIP---KRDSPEFTEMRYTACTSDPDTFVEDGYNLRMAEMNRECQIT 248
L +D P P LR ++ +++ E + +RY+A T P+ +G LR R+ QI
Sbjct: 189 LTIDCPTPIDLRGMLGPFMQKNPDEASFLRYSAITCQPEDMNNNGLQLRTWSTGRDIQIA 248
Query: 249 ICVTMYNEDKFALARTLHSIQKNVAHLCKRHKSNVWGPTGWKTVQIIIISDGRSRINQGS 308
+C+T+ +ED + A +L SI N+ HLC R KS VWG W+ V + ++ DGR+ ++Q
Sbjct: 249 VCLTLSDEDLASFAISLSSIMNNLKHLCSRSKSRVWGNESWEKVLVCVVIDGRNTVHQNV 308
Query: 309 LDYLAAIGVYQEDMAKSTVNGEPVKAHIFELTTQVSIDEELNYRS---EGTVPCQMVFCL 365
LD LA+IGVYQ +AK VNG+ +H++E T+ +++DE+LN + +G VP QM+ C+
Sbjct: 309 LDLLASIGVYQPHIAKGRVNGKRTLSHMYEFTSTINVDEKLNLTTATGDGNVPMQMLLCV 368
Query: 366 KEENQKKINSHRWLFNAFCPILDPTVVTLVDVGTKLNSTAVYHLWKVFDMDSNVAGAAGQ 425
K+ NSHRW N + P V V G +L T++YH WK FD+DS + G G+
Sbjct: 369 KDRRLGTYNSHRWFLNGIASLARPKVCLFVRNGARLGPTSIYHAWKAFDVDSTIGGMCGK 428
Query: 426 IKTMKGKFDMKLLNPLVAAQNFEYKMSNILDKPLESVFGYITVLPGALSAYRYRALKNND 485
GKF +LLNP +A+Q+F+ + N L P +S GYI+ A+ +RY AL+++
Sbjct: 429 TSIDTGKFGFRLLNPFIASQHFDQMIHNNLRLPYDSCMGYISNALNAIYGFRYVALQDSY 488
Query: 486 DGTGPLHSYFLGETQEGRDHDVFTANMYLAEDRILCWELVAKRDEAWVLKYVKEATGETD 545
GPL YF + E + +N +LA++++L W+++ ++D W L+YV EA +
Sbjct: 489 PNPGPLADYFEQDQYEIPRRGILQSNAFLAQEQLLFWKVITRKDAKWHLQYVPEACATIE 548
Query: 546 VPEEPPEFISQRRRWLNGAMFSALYAQIHFHQIWKTRHSTTRKFFFHIEFLYQLVQMIFS 605
P + ++ +N + A+Y + F +W TRH R ++ L ++ + +
Sbjct: 549 APNSMAGILESKKSEINSSFSLAVYVIVDFFSLWTTRHKFFRFLLLTVQSLVFAIEKLVN 608
Query: 606 WFSISNFFLTFYYL--AGSMNSIIPHGD---VLFTFFKYLLICNLCALFIISMGNRPQGA 660
+FS++NFFL FY++ A S +S+ P+G+ LF F+Y+LIC + + F+++MGNRP+
Sbjct: 609 FFSMANFFLAFYFVCNATSYSSLNPYGNWARPLFLVFEYILICLIFSQFMLAMGNRPRSC 668
Query: 661 NHLFISSMVMLTICSTYALVCGLVFAIKTLDDGTEEHSV-----FVNIVVSLLSTYGLYA 715
L S + +I Y + C ++ L + V F ++ S L YA
Sbjct: 669 RVLLFISTALFSIIMIYFVFCVFYISLIPLHNSDNSEIVLGNNYFTTLIFSSLLILACYA 728
Query: 716 FTSLLYLDPWHIFTSSVQYLLMLPSFICTLQIFAFCNTHDVSWGTKGSTEAAK-PIPSAE 774
F SL+ +DP+ IFT VQY+L++P+ I T QI+A C+ D S + +
Sbjct: 729 FVSLICMDPFFIFTCIVQYILLMPTRIYTEQIYALCHLDDASISKDDNQQEFNFDTGITH 788
Query: 775 VIQGPDGITIVTDQWPQDIDNKYQELKSRLKEKEMVEEKVDL-------TQKQNDYYRDI 827
+G T ++ +++ Y D+ Q D+Y+DI
Sbjct: 789 CSMNDEGYTTISIPKANVLNSVYNSSLKNFSSSNDTSVYHDVQDHCYRKPQSYEDHYQDI 848
Query: 828 RTRIVMVWMLSNLILMMIITQIYEPEETVNNIYLKFILWSVAALAAFRATGSIIFLLMKY 887
RTR V+VW +SNLIL +++ Q+++ +NN Y+K+I WS+ A A++ G++ F+ K
Sbjct: 849 RTRYVLVWAVSNLILAIVLIQVFDGMRFINNGYMKYIFWSIVAFTAWKTMGAVTFIATKI 908
Query: 888 L 888
+
Sbjct: 909 I 909
>7296513 [M] KOG2571 Chitin synthase/hyaluronan synthase
(glycosyltransferases)
Length = 1403
Score = 78.6 bits (192), Expect = 4e-14
Identities = 98/422 (23%), Positives = 167/422 (39%), Gaps = 54/422 (12%)
Query: 440 PLVAAQNFEYKMSNILDKPLESVFGYITVLPGALSAYRYRALKNNDDGTGPLHSYFLGET 499
P+V Q FEY + + L K E V G + PG S +R AL N ++ E
Sbjct: 769 PMVWYQRFEYAIGHWLQKATEHVIGCVLCSPGCFSLFRASALMEN--SVMKRYTMISSEA 826
Query: 500 QEGRDHDVFTANMYLAEDRILCWELVAKRDEAWVLKYVKEATGETDVPEEPPEFISQRRR 559
+ +D EDR LC L+ ++Y + T PE EF +QRRR
Sbjct: 827 MKMVQYD-------QGEDRWLCTLLLKAGSR---VEYCAASDAYTHAPESFNEFYNQRRR 876
Query: 560 WLNGAMFSALYAQIHFHQIWKTRHSTTRKFFFHIEFLYQLVQMIFSWFSISNFFLTFYYL 619
W+ + + + K +S + + + YQ + MI + FL
Sbjct: 877 WVPSTIANIFDILADADTVVKKNNSISTMYVW-----YQGMLMIGTVLGPGTIFLMMVGA 931
Query: 620 AGSMNSIIPHGDVLFTFFKYLLICNLCALFIISMGNRPQGANHLFISSMVMLTICSTYAL 679
++ SI L+ FF LL C + + + Q ISS+ L + A+
Sbjct: 932 LVAVFSIDIWTAFLWNFFPILLFILAC----VYLKQKFQLLIAFVISSVYCLVM---MAV 984
Query: 680 VCGLVFAIKTLDDGTEEHSVFVNIVVSLLSTYGLYAFTSLLYLDPWHIFTSSVQYLLMLP 739
+ G++ ++ L+DG + ++V++ T ++ + V Y + +P
Sbjct: 985 LIGII--VQMLEDGPLAPASLFFLLVAVQIT-----IAGFMHPQEFWALLCGVIYYITIP 1037
Query: 740 SFICTLQIFAFCNTHDVSWGTKGSTEAAKPIPSAEVIQGPDGITIVTDQWPQD---IDNK 796
S L IF+ N +DVSWGT+ + P+ + D W D ID++
Sbjct: 1038 SMYMLLMIFSVFNMNDVSWGTREA-----PVLKDDGKDAVDEANNYLPGWLNDPLLIDSE 1092
Query: 797 YQE------------LKSRLKEKEMVEEKVDLTQKQNDYYRDIRTRIVMVWMLSNLILMM 844
E +K LK E+ E+ Q D +++R I +++ N I ++
Sbjct: 1093 LGEVSLMEQRFWKDLIKQYLKPLELSREQ---KQAMADGLKELRNMIAFAFVMVNAIFVL 1149
Query: 845 II 846
I+
Sbjct: 1150 IV 1151
>CE10722 [M] KOG2571 Chitin synthase/hyaluronan synthase
(glycosyltransferases)
Length = 1635
Score = 76.3 bits (186), Expect = 2e-13
Identities = 84/377 (22%), Positives = 147/377 (38%), Gaps = 40/377 (10%)
Query: 386 ILDPTVVTLVDVGTKLNSTAVYHLWKVFDMDSNVAGAAGQIKTMKGKFDMKLLNPLVAAQ 445
I + T + +D ++VY L + + + A G+I +V Q
Sbjct: 856 ISENTFILTLDGDVDFTPSSVYLLVDLMKKNRRLGAACGRIHPRGD-------GAMVWYQ 908
Query: 446 NFEYKMSNILDKPLESVFGYITVLPGALSAYRYRALKNNDDGTGPLHSYFLGETQEGRDH 505
FEY + + L K E + G + PG S +R AL DD ++ E + +
Sbjct: 909 KFEYAIGHWLQKATEHMIGCVMCSPGCFSLFRAYALM--DDNVARRYALKSEEPKHFIQY 966
Query: 506 DVFTANMYLAEDRILCWELVAKRDEAWVLKYVKEATGETDVPEEPPEFISQRRRWLNGAM 565
D EDR LC L+ + + ++Y + +T PE EF +QRRRW+ +
Sbjct: 967 DQ-------GEDRWLCTLLLQR---GYRVEYCAASDAQTFAPEGFNEFFNQRRRWIPSTI 1016
Query: 566 FSALYAQIHFHQIWKTRHSTTRKFFFHIEFLYQLVQMIFSWFSISNFFLTFYYLAGSMNS 625
F+ + + + + S + + +YQLV +I S F+ S
Sbjct: 1017 FNIMDLLKDYRNVVRVNESISIWYI-----IYQLVMLISSILGPGTIFVMIIGAISISFS 1071
Query: 626 IIPHGDVLFTFFKYLLICNLCALFIISMGNRPQGANHLFISSMVMLTICSTYALVCGLVF 685
I D L + ++ + ++ + +P+ H I + + I + +
Sbjct: 1072 I----DTLISLV--IVSIPVVVFIVVCLTAKPE---HQLICAQTIGAIFAMLMTAVVVGT 1122
Query: 686 AIKTLDDGT-EEHSVFVNIVVSLLSTYGLYAFTSLLYLDPWHIFTSSVQYLLMLPSFICT 744
+++ DG HS+F V + T + + P I Y L +P
Sbjct: 1123 SLQLQKDGLLSPHSMFTVAVATSFLTAAILHPLEFTCIIPGTI------YFLAIPCMYML 1176
Query: 745 LQIFAFCNTHDVSWGTK 761
L I++ CN H VSWGT+
Sbjct: 1177 LPIYSVCNMHTVSWGTR 1193
>CE06511 [M] KOG2571 Chitin synthase/hyaluronan synthase
(glycosyltransferases)
Length = 1380
Score = 76.3 bits (186), Expect = 2e-13
Identities = 120/644 (18%), Positives = 247/644 (37%), Gaps = 103/644 (15%)
Query: 220 TACTSDPDTFVE-DGYNLRMAEMNRECQITICVTMYNEDKFALARTLHSIQK-NVAHLCK 277
T T + D E D +R E++R + C TM++E + + + L SI K +V H +
Sbjct: 519 TMLTEEEDISDENDELRIRNDEVDRVSTVYGCATMWHETETEMRQVLRSILKLDVDHATR 578
Query: 278 -----------RHKSNVWGPTGWKTVQIIIISDGRSRINQGSLDYLAAIGVYQEDMAKST 326
R + +++ W+ V+ DG + +Y +M
Sbjct: 579 MNNKKANELRYRLEGHIFFDDAWEDVE----EDGIEKRQPN--EYFNMFFDLLNEMTGER 632
Query: 327 VNGEPVKAHIFELTTQVSIDEELNYRSEGTVPCQMVFCLKEENQKKI-NSHRWLFNAF-- 383
+N E ++ T++ ++ R +P + + +++K I + RW +
Sbjct: 633 LNEEG------KMETRILVNTPYGGRLVVKLPSGTLLFVHLKDKKMIRHKKRWSQVMYMY 686
Query: 384 ---------CPI--------LDPTVVTLVDVGTKLNSTAVYHLWKVFDMDSNVAGAAGQI 426
CP+ D T + +D +K A+ L + + S++ A G+I
Sbjct: 687 YLLGHRIMDCPLSIEDRQQMADNTFILAIDGDSKFEPDALLRLLHLMNAKSDIGCACGRI 746
Query: 427 KTMKGKFDMKLLNPLVAAQNFEYKMSNILDKPLESVFGYITVLPGALSAYRYRALKNNDD 486
+ +V Q FEY +++ K E VFG + PG S +R AL DD
Sbjct: 747 HPIGNGI-------MVWYQKFEYAIAHWFQKAAEHVFGCVLCAPGCFSLFRASALM--DD 797
Query: 487 GTGPLHSYFLGETQEGRDHDVFTANMYLAEDRILCWELVAKRDEAWVLKYVKEATGETDV 546
++ E + +D EDR W + + ++Y + ET
Sbjct: 798 NIMHKYTKTASEPRHYVQYD-------QGEDR---WLSTLLLKQGYRIEYAAASDAETYA 847
Query: 547 PEEPPEFISQRRRWLNGAMFSALYAQIHFHQIWKTRHSTTRKFFFHIEFLYQLVQMIFSW 606
PE EF +QRRRW ++ + + + + R S + YQ + + FS
Sbjct: 848 PEGFEEFFNQRRRWTPSSIANTVDLLMDY-----KRASENNDAISYAYIAYQFLVIFFSM 902
Query: 607 FSISNFF--LTFYYLAG---SMNSIIPHGDVLFTFFKYLLICNLCALFIISMGNRPQGAN 661
+ F L F +A + ++ + + FF +++C I + +
Sbjct: 903 LGPAIIFTMLVFAQVAAFELRGSDVMLYNGIPIGFF--IVLCFTTESNIQLIYAKYMSIA 960
Query: 662 HLFISSMVMLTICSTYALVCGLVFAIKTLDDGTEEHSVFVNIVVSLLSTYGLYAFTSLLY 721
+ F+ V++ S L +V + +++ G++ F + L+
Sbjct: 961 YAFVMLAVLVATSSQIVL-----------------ETVLAPTSLFIVTMVGIFFFAACLH 1003
Query: 722 LDPWHIFTSSVQYLLMLPSFICTLQIFAFCNTHDVSWGT-----KGSTEAAKPIPSAEVI 776
+ V + LM+PS L +++ N + ++WGT K + + K P + I
Sbjct: 1004 PKEFTNIIHGVVFFLMIPSTYVFLTLYSLINLNVITWGTREAVAKATGQKTKKAPMEQFI 1063
Query: 777 QG-----PDGITIVTDQWPQDIDNKYQELKSRLKEKEMVEEKVD 815
G +++ + ++ + + ++++ +++ E+ ++
Sbjct: 1064 DRVIDIVKKGFRLISCREKKEHEERREKMEKKMQRMELALRSIE 1107
>YBR023c [M] KOG2571 Chitin synthase/hyaluronan synthase
(glycosyltransferases)
Length = 1165
Score = 65.9 bits (159), Expect = 3e-10
Identities = 53/177 (29%), Positives = 83/177 (45%), Gaps = 9/177 (5%)
Query: 392 VTLVDVGTKLNSTAVYHLWKVFDMDSNVAGAAGQIKTMKGKFDMKLLNPLVAAQNFEYKM 451
V +VD TK+ A+ H+ D + G G+ K K + + A Q FEY +
Sbjct: 831 VLMVDADTKVFPDALTHMVAEMVKDPLIMGLCGETKIAN-----KAQSWVTAIQVFEYYI 885
Query: 452 SNILDKPLESVFGYITVLPGALSAYRYRALKNNDDGTGPL--HSYFLGETQEGRDHDVFT 509
S+ K ESVFG +T LPG S YR ++ K +D P+ + + + + +
Sbjct: 886 SHHQAKAFESVFGSVTCLPGCFSMYRIKSPKGSDGYWVPVLANPDIVERYSDNVTNTLHK 945
Query: 510 AN-MYLAEDRILCWELVAKRDEAWVLKYVKEATGETDVPEEPPEFISQRRRWLNGAM 565
N + L EDR L L+ K +V +A +T P++ +SQRRRW+N +
Sbjct: 946 KNLLLLGEDRFLS-SLMLKTFPKRKQVFVPKAACKTIAPDKFKVLLSQRRRWINSTV 1001
>Hs20302153 [M] KOG2571 Chitin synthase/hyaluronan synthase
(glycosyltransferases)
Length = 553
Score = 53.9 bits (128), Expect = 1e-06
Identities = 81/382 (21%), Positives = 146/382 (38%), Gaps = 58/382 (15%)
Query: 243 RECQITICVTMYNEDKFALARTLHSIQKNVAHLCKRHKSNVWGPTGWKTVQIIIISDGRS 302
R + +C+ Y ED L + L S Q+ + ++++++ DG
Sbjct: 83 RRGSVALCIAAYQEDPDYLRKCLRSAQR----------------ISFPDLKVVMVVDGNR 126
Query: 303 RINQGSLDYLAAIGVYQEDMAKSTVNGEPVKAHIF----ELTTQVSIDEELNYRSEGTVP 358
+ + LD ++ E + + G V F E T+ S+ E ++ R V
Sbjct: 127 QEDAYMLD------IFHEVLGGTEQAGFFVWRSNFHEAGEGETEASLQEGMD-RVRDVVR 179
Query: 359 CQMVFCLKEENQKKINSHRWLFNAFCPILDPT-VVTLVDVGTKLNSTAVYHLWKVFDMDS 417
C+ QK ++ AF + D + + D T L+ + +V + D
Sbjct: 180 ASTFSCIM---QKWGGKREVMYTAFKALGDSVDYIQVCDSDTVLDPACTIEMLRVLEEDP 236
Query: 418 NVAGAAGQIKTMKGKFDMKLLNPLVAAQNFEYKMSNILDKPLESVFGYITVLPGALSAYR 477
V G G ++ + K+D + + + Y M+ +++ +S FG + + G L YR
Sbjct: 237 QVGGVGGDVQILN-KYD----SWISFLSSVRYWMAFNVERACQSYFGCVQCISGPLGMYR 291
Query: 478 YRALKNNDDGTGPLHSYFLGETQEGRDHDVFTANMYLAEDRILCWELVAKRDEAWVLKYV 537
L+ + H FLG + +DR L +++ + KY
Sbjct: 292 NSLLQQFLEDW--YHQKFLG------------SKCSFGDDRHLTNRVLSL---GYRTKYT 334
Query: 538 KEATGETDVPEEPPEFISQRRRWLNGAMFSALYAQI--HFHQIWKTRHSTTRKF--FFHI 593
+ T+ P + +++Q+ RW LY + H H +W T S F FF I
Sbjct: 335 ARSKCLTETPTKYLRWLNQQTRWSKSYFREWLYNSLWFHKHHLWMTYESVVTGFFPFFLI 394
Query: 594 EFLYQLVQMIFSWFSISNFFLT 615
+ QL W +I F LT
Sbjct: 395 ATVIQLFYRGRIW-NILLFLLT 415
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.321 0.136 0.410
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 56,718,448
Number of Sequences: 60738
Number of extensions: 2530736
Number of successful extensions: 6242
Number of sequences better than 1.0e-05: 9
Number of HSP's better than 0.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 6201
Number of HSP's gapped (non-prelim): 16
length of query: 918
length of database: 30,389,216
effective HSP length: 116
effective length of query: 802
effective length of database: 23,343,608
effective search space: 18721573616
effective search space used: 18721573616
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)