ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIV1025 good E KOG0053 Amino acid transport and metabolism Cystathionine beta-lyases/cystathionine gamma-synthases
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIV1025 336499 337830 444
(444 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YLR303w [E] KOG0053 Cystathionine beta-lyases/cystathionine gamm... 729 0.0
SPBC428.11 [E] KOG0053 Cystathionine beta-lyases/cystathionine g... 510 e-144
CE07648 [E] KOG0053 Cystathionine beta-lyases/cystathionine gamm... 177 2e-44
7302582 [E] KOG0053 Cystathionine beta-lyases/cystathionine gamm... 171 2e-42
HsM4503125 [E] KOG0053 Cystathionine beta-lyases/cystathionine g... 170 3e-42
Hs21361334 [E] KOG0053 Cystathionine beta-lyases/cystathionine g... 170 3e-42
CE15884 [E] KOG0053 Cystathionine beta-lyases/cystathionine gamm... 163 4e-40
At3g57050 [E] KOG0053 Cystathionine beta-lyases/cystathionine ga... 162 7e-40
At3g01120 [E] KOG0053 Cystathionine beta-lyases/cystathionine ga... 157 4e-38
CE17400 [E] KOG0053 Cystathionine beta-lyases/cystathionine gamm... 152 1e-36
YAL012w [E] KOG0053 Cystathionine beta-lyases/cystathionine gamm... 144 3e-34
At1g33320 [E] KOG0053 Cystathionine beta-lyases/cystathionine ga... 134 2e-31
At1g64660 [E] KOG0053 Cystathionine beta-lyases/cystathionine ga... 114 4e-25
YGL184c [E] KOG0053 Cystathionine beta-lyases/cystathionine gamm... 90 8e-18
YFR055w [E] KOG0053 Cystathionine beta-lyases/cystathionine gamm... 80 8e-15
>YLR303w [E] KOG0053 Cystathionine beta-lyases/cystathionine gamma-synthases
Length = 444
Score = 729 bits (1883), Expect = 0.0
Identities = 352/444 (79%), Positives = 387/444 (86%), Gaps = 1/444 (0%)
Query: 1 MPSHFDTLQLHAGQEKTAD-AHNPRAVPIYATTSYVFNDSKHGAQLFGLETPGYIYSRIM 59
MPSHFDT+QLHAGQE D AH RAVPIYATTSYVF +SKHG+QLFGLE PGY+YSR
Sbjct: 1 MPSHFDTVQLHAGQENPGDNAHRSRAVPIYATTSYVFENSKHGSQLFGLEVPGYVYSRFQ 60
Query: 60 NPTLDVLEKRXXXXXXXXXXXXTSSGQAAQTLAVTGLAHTGDNIVSTSFLYGGTYNQFKV 119
NPT +VLE+R SSGQAAQTLA+ GLAHTGDNIVSTS+LYGGTYNQFK+
Sbjct: 61 NPTSNVLEERIAALEGGAAALAVSSGQAAQTLAIQGLAHTGDNIVSTSYLYGGTYNQFKI 120
Query: 120 AFKRLGIEARFVDGDKPEDFEKLFDEKTKALYLESIGNPKYNVPDFEKIVAVAHKHGIPV 179
+FKR GIEARFV+GD PE+FEK+FDE+TKA+YLE+IGNPKYNVPDFEKIVA+AHKHGIPV
Sbjct: 121 SFKRFGIEARFVEGDNPEEFEKVFDERTKAVYLETIGNPKYNVPDFEKIVAIAHKHGIPV 180
Query: 180 VVDNTFGAGGFFCQPIKYGADIVTHSATKWXXXXXXXXXXXXXDSGKFPWKDYPEKFPQF 239
VVDNTFGAGG+FCQPIKYGADIVTHSATKW DSGKFPWKDYPEKFPQF
Sbjct: 181 VVDNTFGAGGYFCQPIKYGADIVTHSATKWIGGHGTTIGGIIVDSGKFPWKDYPEKFPQF 240
Query: 240 SQPSEGYHGLIFNDAFGPAAFIGHVRTELLRDLGPVLSPFAGFLLLQGLETLSLRGERHG 299
SQP+EGYHG I+N+A+G A+I HVRTELLRDLGP+++PFA FLLLQG+ETLSLR ERHG
Sbjct: 241 SQPAEGYHGTIYNEAYGNLAYIVHVRTELLRDLGPLMNPFASFLLLQGVETLSLRAERHG 300
Query: 300 SNALKLAQYLESSPYVSWVSYPGLPSHSHHENAKKYLENGFGGVLSFGVKDLPNASEESD 359
NALKLA++LE SPYVSWVSYPGL SHSHHENAKKYL NGFGGVLSFGVKDLPNA +E+D
Sbjct: 301 ENALKLAKWLEQSPYVSWVSYPGLASHSHHENAKKYLSNGFGGVLSFGVKDLPNADKETD 360
Query: 360 PFKASGAQVVDNLKLASNLANVGDSKTLVIAPYFTTHQQLTDEEKLASGVTKDLIRVSVG 419
PFK SGAQVVDNLKLASNLANVGD+KTLVIAPYFTTH+QL D+EKLASGVTKDLIRVSVG
Sbjct: 361 PFKLSGAQVVDNLKLASNLANVGDAKTLVIAPYFTTHKQLNDKEKLASGVTKDLIRVSVG 420
Query: 420 TEFIDDIIADFEASFATVFNGQKP 443
EFIDDIIADF+ SF TVF GQKP
Sbjct: 421 IEFIDDIIADFQQSFETVFAGQKP 444
>SPBC428.11 [E] KOG0053 Cystathionine beta-lyases/cystathionine gamma-synthases
Length = 429
Score = 510 bits (1313), Expect = e-144
Identities = 260/427 (60%), Positives = 307/427 (71%), Gaps = 11/427 (2%)
Query: 4 HFDTLQLHAGQEKTADAHNPRAVPIYATTSYVFNDSKHGAQLFGLETPGYIYSRIMNPTL 63
HF+TLQLHAGQE A A + RAVPIYATTSYVF D HG +LFGL+ PGYIYSR+MNPT
Sbjct: 7 HFETLQLHAGQEPDA-ATSSRAVPIYATTSYVFRDCDHGGRLFGLQEPGYIYSRMMNPTA 65
Query: 64 DVLEKRXXXXXXXXXXXXTSSGQAAQTLAVTGLAHTGDNIVSTSFLYGGTYNQFKVAFKR 123
DV EKR TSSG +A +A+T LA GDNIVSTS+LYGGTYN FKV R
Sbjct: 66 DVFEKRIAALEHGAAAIATSSGTSALFMALTTLAKAGDNIVSTSYLYGGTYNLFKVTLPR 125
Query: 124 LGIEARFVDGDKPEDFEKLFDEKTKALYLESIGNPKYNVPDFEKIVAVAHKHGIPVVVDN 183
LGI +FV+GD P D DE TKA+Y+ESIGNP YNVPDFE+I VAH G+P++VDN
Sbjct: 126 LGITTKFVNGDDPNDLAAQIDENTKAVYVESIGNPMYNVPDFERIAEVAHAAGVPLMVDN 185
Query: 184 TFGAGGFFCQPIKYGADIVTHSATKWXXXXXXXXXXXXXDSGKFPWKDYPEKFPQFSQPS 243
TFG GG+ +PI +GADIVTHSATKW DSGKF WK ++FP+F++P
Sbjct: 186 TFGGGGYLVRPIDHGADIVTHSATKWIGGHGTTIGGVIVDSGKFDWKKNSKRFPEFNEPH 245
Query: 244 EGYHGLIFNDAFGPAAFIGHVRTELLRDLGPVLSPFAGFLLLQGLETLSLRGERHGSNAL 303
GYHG++F + FG A+ RT+ LRD+G +PF FLLLQGLETLSLR ERH NA
Sbjct: 246 PGYHGMVFTETFGNLAYAFACRTQTLRDVGGNANPFGVFLLLQGLETLSLRMERHVQNAF 305
Query: 304 KLAQYLESSPYVSWVSYPGLPSHSHHENAKKYLENGFGGVLSFGVKDLPNASEESDPFKA 363
LA+YLE P V+WVSYPGL SH H+ AKKYL+NG+G VLSFG K P+ S
Sbjct: 306 ALAKYLEKHPKVNWVSYPGLESHVSHKLAKKYLKNGYGAVLSFGAKGGPDQSR------- 358
Query: 364 SGAQVVDNLKLASNLANVGDSKTLVIAPYFTTHQQLTDEEKLASGVTKDLIRVSVGTEFI 423
+VV+ LKLAS LANVGD+KTLVIAP +TTH QLTDEE++++GVTKDLIRV+VG E I
Sbjct: 359 ---KVVNALKLASQLANVGDAKTLVIAPAYTTHLQLTDEEQISAGVTKDLIRVAVGIEHI 415
Query: 424 DDIIADF 430
DDIIADF
Sbjct: 416 DDIIADF 422
>CE07648 [E] KOG0053 Cystathionine beta-lyases/cystathionine gamma-synthases
Length = 392
Score = 177 bits (450), Expect = 2e-44
Identities = 142/433 (32%), Positives = 203/433 (46%), Gaps = 61/433 (14%)
Query: 4 HFDTLQLHAGQEKTADAHNPRAVPIYATTSYVFNDSKHGAQLFGLETPGYIYSRIMNPTL 63
HF T +H GQE N PI +++Y ++ E G+ YSR NPT
Sbjct: 6 HFGTAAIHVGQEPEQWDMNQVVPPISLSSTYKQDNPG--------EPKGHDYSRAGNPTR 57
Query: 64 DVLEKRXXXXXXXXXXXXTSSGQAAQTLAVTGLAHTGDNIVSTSFLYGGTYNQF-KVAFK 122
DVL+K SSG AA T A+ L GD+IV + +YGGT +VA
Sbjct: 58 DVLQKNLAALEDAKHCQVFSSGLAA-TSAIINLLKYGDHIVCSDDVYGGTQRYIRRVAVP 116
Query: 123 RLGIEARFVDGDKPEDFEKLFDEKTKALYLESIGNPKYNVPDFEKIVAVAHKHG--IPVV 180
G+E VD ++ EK TK ++ ES NP V D +V A K I VV
Sbjct: 117 NHGLEVDSVDLTDVQNLEKAIKPNTKMVWFESPSNPLLKVVDIAAVVQTAKKANPEIVVV 176
Query: 181 VDNTFGAGGFFCQPIKYGADIVTHSATKWXXXXXXXXXXXXXDSGKFPWKDYPEKFPQFS 240
VDNTF +F +PI GAD+V HS TK+ +
Sbjct: 177 VDNTF-MSPYFQRPISLGADVVVHSITKY-----------------------------IN 206
Query: 241 QPSEGYHGLIF--NDAFGPAAFIGHVRTELLRDLGPVLSPFAGFLLLQGLETLSLRGERH 298
S+ G + ND F F + +G V SPF FL+ +GL+TL +R H
Sbjct: 207 GHSDVVMGAVITDNDEFQQHLFFMQLA------VGAVPSPFDCFLVNRGLKTLHIRMRAH 260
Query: 299 GSNALKLAQYLESSPYVSWVSYPGLPSHSHHENAKKYLENGFGGVLSFGVKDLPNASEES 358
NAL +A+YLE++ + V YP LPSH HE +K + G G++SF +K +ES
Sbjct: 261 YENALAVAKYLEANDRIESVLYPALPSHPQHEVHEKQTK-GMSGMISFYLK---GELQES 316
Query: 359 DPFKASGAQVVDNLKLASNLANVGDSKTLVIAPYFTTHQQLTDEEKLASGVTKDLIRVSV 418
F ++ LK+ + ++G ++L P TH + E ++ G+T +LIR+SV
Sbjct: 317 RAFLSA-------LKVFTLAESLGGYESLAELPSIMTHASVPAETRIVLGITDNLIRISV 369
Query: 419 GTEFIDDIIADFE 431
G E +DD++AD +
Sbjct: 370 GIEDLDDLVADLD 382
>7302582 [E] KOG0053 Cystathionine beta-lyases/cystathionine gamma-synthases
Length = 393
Score = 171 bits (433), Expect = 2e-42
Identities = 140/432 (32%), Positives = 200/432 (45%), Gaps = 56/432 (12%)
Query: 2 PSHFDTLQLHAGQEKTADAHNPRAVPIYATTSYVFNDSKHGAQLFGLETPGYIYSRIMNP 61
PS F T +H+GQ + D AV + S F G E GY YSR NP
Sbjct: 7 PSGFATKSIHSGQ--SPDQWKSAAVIPPISLSTTFKQDAPG------EHRGYEYSRSGNP 58
Query: 62 TLDVLEKRXXXXXXXXXXXXTSSGQAAQTLAVTGLAHTGDNIVSTSFLYGGTYNQFKVAF 121
T +VLE SSG A T +T L+ +GD+I+ +YGGT +
Sbjct: 59 TRNVLETCFAALDNAKYGLTFSSGLGATTAVLTMLS-SGDHIIMGDDVYGGTNRLIRQVA 117
Query: 122 KRLGIEARFVDGDKPEDFEKLFDEKTKALYLESIGNPKYNVPDFEKIVAVAH--KHGIPV 179
RLGI A FVD K + + +TK +++ES NP V D E I + H + I +
Sbjct: 118 TRLGISATFVDPTKLDLIKSSIKPETKLVWIESPTNPLVKVADIEAIAQLVHGVREDIVL 177
Query: 180 VVDNTFGAGGFFCQPIKYGADIVTHSATKWXXXXXXXXXXXXXDSGKFPWKDYPEKFPQF 239
VDNTF +F +P++ GAD+V +S TK+ + + +K KF
Sbjct: 178 AVDNTF-LTSYFQRPLELGADLVCYSLTKYMNGHTDVVMGGITMNSEKLYKSL--KF--- 231
Query: 240 SQPSEGYHGLIFNDAFGPAAFIGHVRTELLRDLGPVLSPFAGFLLLQGLETLSLRGERHG 299
L +G V SPF + + + L+TLSLR E+H
Sbjct: 232 ----------------------------LQNAVGIVPSPFDCYQVNRSLKTLSLRMEQHQ 263
Query: 300 SNALKLAQYLESSPYVSWVSYPGLPSHSHHENAKKYLENGFGGVLSFGVKDLPNASEESD 359
NALK+A+YLE++P+V V +P LPSH H+ A K G+ GV SF +K
Sbjct: 264 KNALKVAKYLETNPFVEKVLHPSLPSHPQHKIALKQ-AYGYSGVFSFYIK---------G 313
Query: 360 PFKASGAQVVDNLKLASNLANVGDSKTLVIAPYFTTHQQLTDEEKLASGVTKDLIRVSVG 419
K S A + LK+ + ++G ++L P TH + E++ G+T L+R+SVG
Sbjct: 314 ELKHSSA-FLKALKVFTLAESLGGYESLAELPSIMTHASVPAEDRKTLGITDGLVRLSVG 372
Query: 420 TEFIDDIIADFE 431
E DD+I D E
Sbjct: 373 LEDADDLIKDLE 384
>HsM4503125 [E] KOG0053 Cystathionine beta-lyases/cystathionine gamma-synthases
Length = 405
Score = 170 bits (431), Expect = 3e-42
Identities = 134/430 (31%), Positives = 201/430 (46%), Gaps = 57/430 (13%)
Query: 4 HFDTLQLHAGQEKTADAHNPRAVPIYATTSYVFNDSKHGAQLFGLETPGYIYSRIMNPTL 63
HF T +H GQ+ PI +T++ K GA + G+ YSR NPT
Sbjct: 17 HFATQAIHVGQDPEQWTSRAVVPPISLSTTF-----KQGAPG---QHSGFEYSRSGNPTR 68
Query: 64 DVLEKRXXXXXXXXXXXXTSSGQAAQTLAVTGLAHTGDNIVSTSFLYGGTYNQFKVAFKR 123
+ LEK +SG AA T+ +T L GD I+ +YGGT F+
Sbjct: 69 NCLEKAVAALDGAKYCLAFASGLAA-TVTITHLLKAGDQIICMDDVYGGTNRYFRQVASE 127
Query: 124 LGIEARFVDGDKPEDFEKLFDEKTKALYLESIGNPKYNVPDFEKIVAVAHKHG-IPVVVD 182
G++ FVD K + E +TK +++E+ NP V D E + HKHG I +VVD
Sbjct: 128 FGLKISFVDCSKIKLLEAAITPETKLVWIETPTNPTQKVIDIEGCAHIVHKHGDIILVVD 187
Query: 183 NTFGAGGFFCQPIKYGADIVTHSATKWXXXXXXXXXXXXXDSGKFPWKDYPEKFPQFSQP 242
NTF +F +P+ GADI +SATK+ +
Sbjct: 188 NTF-MSPYFQRPLALGADISMYSATKY-----------------------------MNGH 217
Query: 243 SEGYHGLIFNDAFGPAAFIGHVRTELLRD-LGPVLSPFAGFLLLQGLETLSLRGERHGSN 301
S+ GL+ + H R L++ LG V SP +L +GL+TL +R E+H N
Sbjct: 218 SDVVMGLVSVNCESL-----HNRLRFLQNSLGAVPSPIDCYLCNRGLKTLHVRMEKHFKN 272
Query: 302 ALKLAQYLESSPYVSWVSYPGLPSHSHHENAKKYLENGFGGVLSFGVKDLPNASEESDPF 361
+ +AQ+LES+P+V V YPGLPSH HE K+ G G+++F +K +E
Sbjct: 273 GMAVAQFLESNPWVEKVIYPGLPSHPQHELVKRQC-TGCTGMVTFYIKGTLQHAE----- 326
Query: 362 KASGAQVVDNLKLASNLANVGDSKTLVIAPYFTTHQQLTDEEKLASGVTKDLIRVSVGTE 421
+ NLKL + ++G ++L P TH + ++ G++ LIR+SVG E
Sbjct: 327 -----IFLKNLKLFTLAESLGGFESLAELPAIMTHASVLKNDRDVLGISDTLIRLSVGLE 381
Query: 422 FIDDIIADFE 431
+D++ D +
Sbjct: 382 DEEDLLEDLD 391
>Hs21361334 [E] KOG0053 Cystathionine beta-lyases/cystathionine gamma-synthases
Length = 405
Score = 170 bits (431), Expect = 3e-42
Identities = 134/430 (31%), Positives = 201/430 (46%), Gaps = 57/430 (13%)
Query: 4 HFDTLQLHAGQEKTADAHNPRAVPIYATTSYVFNDSKHGAQLFGLETPGYIYSRIMNPTL 63
HF T +H GQ+ PI +T++ K GA + G+ YSR NPT
Sbjct: 17 HFATQAIHVGQDPEQWTSRAVVPPISLSTTF-----KQGAPG---QHSGFEYSRSGNPTR 68
Query: 64 DVLEKRXXXXXXXXXXXXTSSGQAAQTLAVTGLAHTGDNIVSTSFLYGGTYNQFKVAFKR 123
+ LEK +SG AA T+ +T L GD I+ +YGGT F+
Sbjct: 69 NCLEKAVAALDGAKYCLAFASGLAA-TVTITHLLKAGDQIICMDDVYGGTNRYFRQVASE 127
Query: 124 LGIEARFVDGDKPEDFEKLFDEKTKALYLESIGNPKYNVPDFEKIVAVAHKHG-IPVVVD 182
G++ FVD K + E +TK +++E+ NP V D E + HKHG I +VVD
Sbjct: 128 FGLKISFVDCSKIKLLEAAITPETKLVWIETPTNPTQKVIDIEGCAHIVHKHGDIILVVD 187
Query: 183 NTFGAGGFFCQPIKYGADIVTHSATKWXXXXXXXXXXXXXDSGKFPWKDYPEKFPQFSQP 242
NTF +F +P+ GADI +SATK+ +
Sbjct: 188 NTF-MSPYFQRPLALGADISMYSATKY-----------------------------MNGH 217
Query: 243 SEGYHGLIFNDAFGPAAFIGHVRTELLRD-LGPVLSPFAGFLLLQGLETLSLRGERHGSN 301
S+ GL+ + H R L++ LG V SP +L +GL+TL +R E+H N
Sbjct: 218 SDVVMGLVSVNCESL-----HNRLRFLQNSLGAVPSPIDCYLCNRGLKTLHVRMEKHFKN 272
Query: 302 ALKLAQYLESSPYVSWVSYPGLPSHSHHENAKKYLENGFGGVLSFGVKDLPNASEESDPF 361
+ +AQ+LES+P+V V YPGLPSH HE K+ G G+++F +K +E
Sbjct: 273 GMAVAQFLESNPWVEKVIYPGLPSHPQHELVKRQC-TGCTGMVTFYIKGTLQHAE----- 326
Query: 362 KASGAQVVDNLKLASNLANVGDSKTLVIAPYFTTHQQLTDEEKLASGVTKDLIRVSVGTE 421
+ NLKL + ++G ++L P TH + ++ G++ LIR+SVG E
Sbjct: 327 -----IFLKNLKLFTLAESLGGFESLAELPAIMTHASVLKNDRDVLGISDTLIRLSVGLE 381
Query: 422 FIDDIIADFE 431
+D++ D +
Sbjct: 382 DEEDLLEDLD 391
>CE15884 [E] KOG0053 Cystathionine beta-lyases/cystathionine gamma-synthases
Length = 392
Score = 163 bits (413), Expect = 4e-40
Identities = 137/432 (31%), Positives = 199/432 (45%), Gaps = 59/432 (13%)
Query: 4 HFDTLQLHAGQEKTADAHNPRAVPIYATTSYVFNDSKHGAQLFGLETPGYIYSRIMNPTL 63
HF T +H GQE N PI +T+Y ++ E Y Y+R NPT
Sbjct: 6 HFGTDAVHVGQEPEQWDINQVVPPISMSTTYKQDNPG--------EPKRYDYARGGNPTR 57
Query: 64 DVLEKRXXXXXXXXXXXXTSSGQAAQTLAVTGLAHTGDNIVSTSFLYGGTYNQFK-VAFK 122
DVL+K SSG AA + AV L + GD+IV + +YGGT + +A K
Sbjct: 58 DVLQKNLAALEGAKHCQAFSSGLAASS-AVINLLNHGDHIVCSDDVYGGTIRYIRQIAVK 116
Query: 123 RLGIEARFVDGDKPEDFEKLFDEKTKALYLESIGNPKYNVPDFEKIVAVAHKHG--IPVV 180
+ G+E VD ++ EK TK ++ ES NP V D +V A + I VV
Sbjct: 117 KYGMEVDSVDLTDVQNLEKAIKPNTKMVWFESPSNPLLKVVDIAAVVQTAKRANPEIVVV 176
Query: 181 VDNTFGAGGFFCQPIKYGADIVTHSATKWXXXXXXXXXXXXXDSGKFPWKDYPEKFPQFS 240
VDNTF +F +P+ GADI HS TK+
Sbjct: 177 VDNTF-MTPYFQRPLSLGADIAVHSITKYI------------------------------ 205
Query: 241 QPSEGYHGLIFNDAF-GPAAFIGHVRTELLRDLGPVLSPFAGFLLLQGLETLSLRGERHG 299
G+ +I A F H+ + R +G V SPF FL+ +GL+TL +R + H
Sbjct: 206 ---NGHSDIIMGAAITNNDEFQQHLHF-MQRAIGGVPSPFDCFLVNRGLKTLHVRMKAHF 261
Query: 300 SNALKLAQYLESSPYVSWVSYPGLPSHSHHENAKKYLENGFGGVLSFGVKDLPNASEESD 359
NAL +A++LE+ + V YP LPSH H K + G G++SF +K +S
Sbjct: 262 ENALAIAKFLEAHDCIESVLYPALPSHPQHTVHVKQTK-GMSGMISFYLK---GELCQSR 317
Query: 360 PFKASGAQVVDNLKLASNLANVGDSKTLVIAPYFTTHQQLTDEEKLASGVTKDLIRVSVG 419
F ++ LK+ + ++G ++L P TH + + G+T +LIR+SVG
Sbjct: 318 AFLSA-------LKVFTLAESLGGCESLAELPSIMTHASVPSATRAELGITDNLIRISVG 370
Query: 420 TEFIDDIIADFE 431
E +DD+IAD +
Sbjct: 371 IEDLDDLIADLD 382
>At3g57050 [E] KOG0053 Cystathionine beta-lyases/cystathionine gamma-synthases
Length = 464
Score = 162 bits (411), Expect = 7e-40
Identities = 126/419 (30%), Positives = 187/419 (44%), Gaps = 57/419 (13%)
Query: 19 DAHNPRAVPIYATTSYVFNDSKHGAQLFGLETPGYIYSRIMNPTLDVLEKRXXXXXXXXX 78
D + + P+Y T ++ Q +E Y Y+R NPT D LE
Sbjct: 99 DPFDAMSTPLYQTATF--------KQPSAIENGPYDYTRSGNPTRDALESLLAKLDKADR 150
Query: 79 XXXTSSGQAAQTLAVTGLAHTGDNIVSTSFLYGGTYNQFKVAFKRLGIEARFVDGDKPED 138
+SG AA + AVT L G+ IV+ +YGG+ R G+ + V+ K ++
Sbjct: 151 AFCFTSGMAALS-AVTHLIKNGEEIVAGDDVYGGSDRLLSQVVPRSGVVVKRVNTTKLDE 209
Query: 139 FEKLFDEKTKALYLESIGNPKYNVPDFEKIVAVAHKHGIPVVVDNTFGAGGFFCQPIKYG 198
+TK ++LES NP+ + D KI +AH G V+VDN+ +P++ G
Sbjct: 210 VAAAIGPQTKLVWLESPTNPRQQISDIRKISEMAHAQGALVLVDNSI-MSPVLSRPLELG 268
Query: 199 ADIVTHSATKWXXXXXXXXXXXXXDSGKFPWKDYPEKFPQFSQPSEGYHGLIFNDAFGPA 258
ADIV HSATK+ G+ K+ F Q SEG
Sbjct: 269 ADIVMHSATKFIAGHSDVMAGVLAVKGEKLAKEV-----YFLQNSEGSG----------- 312
Query: 259 AFIGHVRTELLRDLGPVLSPFAGFLLLQGLETLSLRGERHGSNALKLAQYLESSPYVSWV 318
L+PF +L L+G++T++LR E+ NA K+A YL S P V V
Sbjct: 313 -----------------LAPFDCWLCLRGIKTMALRIEKQQENARKIAMYLSSHPRVKKV 355
Query: 319 SYPGLPSH-SHHENAKKYLENGFGGVLSFGVKDLPNASEESDPFKASGAQVVDNLKLASN 377
Y GLP H HH + + G G V SF + A +V+ K S
Sbjct: 356 YYAGLPDHPGHHLHFSQ--AKGAGSVFSFITGSV-----------ALSKHLVETTKYFSI 402
Query: 378 LANVGDSKTLVIAPYFTTHQQLTDEEKLASGVTKDLIRVSVGTEFIDDIIADFEASFAT 436
+ G K+L+ P F +H + E + A G+T+DL+R+S G E +DD+I+D + +F T
Sbjct: 403 AVSFGSVKSLISMPCFMSHASIPAEVREARGLTEDLVRISAGIEDVDDLISDLDIAFKT 461
>At3g01120 [E] KOG0053 Cystathionine beta-lyases/cystathionine gamma-synthases
Length = 563
Score = 157 bits (396), Expect = 4e-38
Identities = 121/425 (28%), Positives = 188/425 (43%), Gaps = 48/425 (11%)
Query: 7 TLQLHAGQEKTAD-AHNPRAVPIYATTSYVFNDSKHGAQLFGLETPGYIYSRIMNPTLDV 65
+L +HAG+ + P+ T++Y F + + + Y R NPT V
Sbjct: 177 SLTVHAGERLGRGIVTDAITTPVVNTSAYFFKKTAELIDFKEKRSVSFEYGRYGNPTTVV 236
Query: 66 LEKRXXXXXXXXXXXXTSSGQAAQTLAVTGLAHTGDNIVSTSFLYGGTYNQFKVAFKRLG 125
LE + +SG A T+ + L G +IV+T+ Y T + +LG
Sbjct: 237 LEDKISALEGAESTLVMASGMCASTVMLLALVPAGGHIVTTTDCYRKTRIFMENFLPKLG 296
Query: 126 IEARFVDGDKPEDFEKLFDE-KTKALYLESIGNPKYNVPDFEKIVAVAHKHGIPVVVDNT 184
I +D E +E K + ES NP D E + + HK G V +D T
Sbjct: 297 ITVTVIDPADIAGLEAAVNEFKVSLFFTESPTNPFLRCVDIELVSKICHKRGTLVCIDGT 356
Query: 185 FGAGGFFCQPIKYGADIVTHSATKWXXXXXXXXXXXXXDSGKFPWKDYPEKFPQFSQPSE 244
F A + + GAD+V HSATK+
Sbjct: 357 F-ATPLNQKALALGADLVVHSATKYIG--------------------------------- 382
Query: 245 GYHGLIFNDAFGPAAFIGHVRTELLRDLGPVLSPFAGFLLLQGLETLSLRGERHGSNALK 304
G++ ++ G + +R L LG L+P A +L+++G++TL LR ++ S A +
Sbjct: 383 GHNDVLAGCICGSLKLVSEIRN-LHHVLGGTLNPNAAYLIIRGMKTLHLRVQQQNSTAFR 441
Query: 305 LAQYLESSPYVSWVSYPGLPSHSHHENAKKYLENGFGGVLSFGVKDLPNASEESDPFKAS 364
+A+ LE+ P VS V YPGLPSH HE AK+ + GFGGV+SF E D +
Sbjct: 442 MAEILEAHPKVSHVYYPGLPSHPEHELAKRQM-TGFGGVVSF----------EIDGDIET 490
Query: 365 GAQVVDNLKLASNLANVGDSKTLVIAPYFTTHQQLTDEEKLASGVTKDLIRVSVGTEFID 424
+ VD+LK+ + G +++V P ++ L EE+L G+ +L+R S G E +
Sbjct: 491 TIKFVDSLKIPYIAPSFGGCESIVDQPAIMSYWDLPQEERLKYGIKDNLVRFSFGVEDFE 550
Query: 425 DIIAD 429
D+ AD
Sbjct: 551 DVKAD 555
>CE17400 [E] KOG0053 Cystathionine beta-lyases/cystathionine gamma-synthases
Length = 444
Score = 152 bits (384), Expect = 1e-36
Identities = 127/436 (29%), Positives = 187/436 (42%), Gaps = 72/436 (16%)
Query: 4 HFDTLQLHAGQEKTADAHNPRAVPIYATTSY------VFNDSKHGAQLFGLETPGYIYSR 57
H D+ ++ K +P VPIY +++Y FN+ HGA ++Y R
Sbjct: 63 HLDS-RISTSHAKPLSNADPVVVPIYHSSTYRFKTVDQFNEDNHGAN--------FVYRR 113
Query: 58 IMNPTLDVLEKRXXXXXXXXXXXXTSSGQAAQTLAVTGLAHTGDNIVSTSFLYGGTYNQF 117
NPT + +E +SG AA + +G +++ + +Y GT +
Sbjct: 114 CGNPTTENVEVVINEIEGGAGSLLYNSGLAAISAVFLEFLSSGAHMIVMNPIYSGTSSFI 173
Query: 118 KVAFKRLGIEARFVDGDKPEDF----EKLFDEKTKALYLESIGNPKYNVPDFEKIVAVAH 173
R G+E VD +K +DF EK TK +Y ESI NP VPD + VA
Sbjct: 174 NETLARFGVEITSVDVEKEKDFAGAVEKAIRPNTKMIYFESIANPTMAVPDILGTIEVAK 233
Query: 174 KHGIPVVVDNTFGAGGFFCQPIKYGADIVTHSATKWXXXXXXXXXXXXXDSGKFPWKDYP 233
K+ I +D TF + + QP+K GADI HS +K+ S WK
Sbjct: 234 KYKILTCLDATF-SSPYNIQPLKLGADISLHSCSKYIGGHTDVIAGVVTVSSYDNWKKL- 291
Query: 234 EKFPQFSQPSEGYHGLIFNDAFGPAAFIGHVRTELLRDLGPVLSPFAGFLLLQGLETLSL 293
K Q + G LSP+ LL +GL+TL L
Sbjct: 292 -KLQQLT-------------------------------TGSSLSPYDAALLTRGLKTLGL 319
Query: 294 RGERHGSNALKLAQYLESSPYVSWVSYPGLPSHSHHENAKKYLENGFGGVLSFGVKDLPN 353
R +R NA K A++LES P V V YPGLPSH H+ AK+ ++ F G+++F V N
Sbjct: 320 RVDRISENAQKTAEFLESHPKVERVFYPGLPSHPQHQYAKQVMKQ-FAGMIAFDVGTAEN 378
Query: 354 ASEESDPFKASGAQVVDNLKLASNLANVGDSKTLVIAPYFTTHQQLTDEEKLASGVTKDL 413
A +KL + ++G +++L+ P +H + V L
Sbjct: 379 A-----------------IKLVEAI-SLGGTESLIEHPLSMSHGKHLLRYLDGPTVAPGL 420
Query: 414 IRVSVGTEFIDDIIAD 429
+R SVG E ++DII D
Sbjct: 421 LRFSVGIENVEDIIGD 436
>YAL012w [E] KOG0053 Cystathionine beta-lyases/cystathionine gamma-synthases
Length = 394
Score = 144 bits (363), Expect = 3e-34
Identities = 125/441 (28%), Positives = 193/441 (43%), Gaps = 61/441 (13%)
Query: 5 FDTLQLHAGQEKTADAHNPRAVPIYATTSYVFNDSKHGAQLFGLETPGYIYSRIMNPTLD 64
F T +HAG+ D H PI +T++ K + + T Y YSR NP +
Sbjct: 9 FATKAIHAGEH--VDVHGSVIEPISLSTTF-----KQSSPANPIGT--YEYSRSQNPNRE 59
Query: 65 VLEKRXXXXXXXXXXXXTSSGQAAQTLAVTGLAHTGDNIVSTSFLYGGTYNQFKVAFKRL 124
LE+ SSG A + L G + VS +YGGT+ F
Sbjct: 60 NLERAVAALENAQYGLAFSSGSATTATILQSLPQ-GSHAVSIGDVYGGTHRYFTKVANAH 118
Query: 125 GIEARFVDGDKPEDFEKLFDEKTKALYLESIGNPKYNVPDFEKIVAVAHKHG----IPVV 180
G+E F + D D +L E TK +++E+ NP V D +K+ + KH + +V
Sbjct: 119 GVETSFTN-DLLNDLPQLIKENTKLVWIETPTNPTLKVTDIQKVADLIKKHAAGQDVILV 177
Query: 181 VDNTFGAGGFFCQPIKYGADIVTHSATKWXXXXXXXXXXXXXDSGKFPWKDYPEKFPQFS 240
VDNTF + P+ +GADIV HSATK+ + K
Sbjct: 178 VDNTF-LSPYISNPLNFGADIVVHSATKYINGHSDVVLGVLATNNK-------------- 222
Query: 241 QPSEGYHGLIFNDAFGPAAFIGHVRTELLRDLGPVLSPFAGFLLLQGLETLSLRGERHGS 300
Y L F L +G + SPF +L +GL+TL LR +
Sbjct: 223 ---PLYERLQF----------------LQNAIGAIPSPFDAWLTHRGLKTLHLRVRQAAL 263
Query: 301 NALKLAQYLES-SPYVSWVSYPGLPSHSHHENAKKYLENGF-GGVLSFGVKDLPNASEES 358
+A K+A++L + V V+YPGL +H +++ K + GG++SF +K +E +
Sbjct: 264 SANKIAEFLAADKENVVAVNYPGLKTHPNYDVVLKQHRDALGGGMISFRIK---GGAEAA 320
Query: 359 DPFKASGAQVVDNLKLASNLANVGDSKTLVIAPYFTTHQQLTDEEKLASGVTKDLIRVSV 418
F +S +L + ++G ++L+ P TH + E + ASGV DL+R+SV
Sbjct: 321 SKFASS-------TRLFTLAESLGGIESLLEVPAVMTHGGIPKEAREASGVFDDLVRISV 373
Query: 419 GTEFIDDIIADFEASFATVFN 439
G E DD++ D + + N
Sbjct: 374 GIEDTDDLLEDIKQALKQATN 394
>At1g33320 [E] KOG0053 Cystathionine beta-lyases/cystathionine gamma-synthases
Length = 412
Score = 134 bits (338), Expect = 2e-31
Identities = 114/408 (27%), Positives = 175/408 (41%), Gaps = 48/408 (11%)
Query: 31 TTSYVFNDSKHGAQLFGLETPGYIYSRIMNPTLDVLEKRXXXXXXXXXXXXTSSGQAAQT 90
TT+Y F D+ Y Y+R NPT LE++ +SG A
Sbjct: 52 TTTYFFKDTTELIDFKEKRIDLYEYARYGNPTTMALEEKISVLEGAESTLVMASGMYASN 111
Query: 91 LAVTGLAHTGDNIVSTSFLYGGTYNQFKVAFKRLGIEARFVDGDKPEDFEKLFDEKTKAL 150
+ + L T +IV+T Y T + +LGI F+D D + L + +L
Sbjct: 112 VMLLALVPTNGHIVATKDCYKETRIFMENFLTKLGITVTFIDSDDIAGLQTLVNNHEVSL 171
Query: 151 YL-ESIGNPKYNVPDFEKIVAVAHKHGIPVVVDNTFGAGGFFCQPIKYGADIVTHSATKW 209
+ ES NP D + + + H+ G V +D T A + + GAD+V HSATK+
Sbjct: 172 FFTESPTNPFLRCVDIKLVSKICHRRGTLVCIDATI-ATPINQKTLALGADLVHHSATKY 230
Query: 210 XXXXXXXXXXXXXDSGKFPWKDYPEKFPQFSQPSEGYHGLIFNDAFGPAAFIGHVRTELL 269
G++ + G + +R L
Sbjct: 231 IG---------------------------------GHNDFLAGSISGSMELVSKIRN-LH 256
Query: 270 RDLGPVLSPFAGFLLLQGLETLSLRGERHGSNALKLAQYLESSPYVSWVSYPGLPSHSHH 329
+ LG L+P A +LL++G++T+ LR + S +K+AQ LE+ P VS V Y GLPSH H
Sbjct: 257 KLLGGTLNPNAAYLLIRGMKTMHLRVRQQNSTGMKMAQVLEAHPKVSRVYYLGLPSHPEH 316
Query: 330 ENAKKYLENGFGGVLSFGVKDLPNASEESDPFKASGAQVVDNLKLASNLANVGDSKTLVI 389
AK+ + G GG++SF E D + + +D LK+ A+ G ++LV
Sbjct: 317 LIAKRQM-TGIGGLISF----------EIDGDLKTTIKFIDALKIPYLAASFGGCESLV- 364
Query: 390 APYFTTHQQLTDEEKLASGVTKDLIRVSVGTEFIDDIIADFEASFATV 437
T + EE+L G +L+R S G E +DI AD + T+
Sbjct: 365 DQLATGIWDIPREERLKDGFQDNLVRFSFGIEDFEDIKADVLQALETI 412
>At1g64660 [E] KOG0053 Cystathionine beta-lyases/cystathionine gamma-synthases
Length = 441
Score = 114 bits (284), Expect = 4e-25
Identities = 101/380 (26%), Positives = 161/380 (41%), Gaps = 51/380 (13%)
Query: 47 GLETPGYIYSRIMNPTLDVLEKRXXXXXXXXXXXXTSSGQAAQTLAVTGLAHTGDNIVST 106
G + Y+YSR NPT+ L ++ TSSG +A + + L +G ++V+
Sbjct: 87 GPDNDFYVYSRHFNPTVLNLSRQMAALEGTQAAYCTSSGMSAISSVMLQLCSSGGHVVAA 146
Query: 107 SFLYGGTYNQFKVAFKRL-GIEARFVD-GDKPEDFEKLFDEKTKALYLESIGNPKYNVPD 164
S LYGGT+ R I FVD D + + +T+ LY ES+ NP V D
Sbjct: 147 STLYGGTHALLSHFLPRTCNITTSFVDITDHGAVANAIVEGRTQVLYFESVANPTLTVAD 206
Query: 165 FEKIVAVAHKHGIPVVVDNTFGAGGFFCQPIKYGADIVTHSATKWXXXXXXXXXXXXXDS 224
++ +AH+ G+ VVVDNTF P K GAD+V HS +K+
Sbjct: 207 IPELSRMAHEKGVTVVVDNTFAP--MVLSPAKLGADVVVHSISKFI-------------- 250
Query: 225 GKFPWKDYPEKFPQFSQPSEGYHGLIFNDAFGPAAFIGH---VRTELLRDLGPVLSPFAG 281
G +I G + +R L LGP ++
Sbjct: 251 -------------------SGGADIIAGAVCGSENLVKEMMDLRGGSLMLLGPTMNAKVA 291
Query: 282 FLLLQGLETLSLRGERHGSNALKLAQYLESSPYVSWVSYPGLPSHSHHENAKKYL--ENG 339
F L + + L LR H A A+ + V YPGL +H H+ K + + G
Sbjct: 292 FELSERIPHLGLRMREHSHRAQVYAERMRDLGMK--VIYPGLETHPQHKLFKGMVNRDYG 349
Query: 340 FGGVLSFGVKDLPNASEESDPFKASGAQVVDNLKLASNLANVGDSKTLVIAPYFTTHQQL 399
+GG+LS ++ A++ A + + + ++G +TL+ +T +L
Sbjct: 350 YGGLLSIDMETEEKANKLM-------AYLQNATQFGFMAVSLGYYETLMSCSGSSTSSEL 402
Query: 400 TDEEKLASGVTKDLIRVSVG 419
+K A+G++ L+R+SVG
Sbjct: 403 DPSQKEAAGISPGLVRMSVG 422
>YGL184c [E] KOG0053 Cystathionine beta-lyases/cystathionine gamma-synthases
Length = 465
Score = 89.7 bits (221), Expect = 8e-18
Identities = 116/453 (25%), Positives = 182/453 (39%), Gaps = 81/453 (17%)
Query: 6 DTLQLHAGQEKTADAHNPRAVPIYATTSYVFNDSKHGAQLFGLETPGYIYSRIMNPTLDV 65
DT+ ++ G + D H+ P+Y +T++ + + AQ Y YSR NPT V
Sbjct: 7 DTVVVNTGSQN--DQHSASVPPVYLSTTFKVDLNNEDAQ-------NYDYSRSGNPTRSV 57
Query: 66 LEKRXXXXXX--XXXXXXTSSGQAAQTLAVTGLA-------HTGDNIVSTSFLYGGTYNQ 116
L+ + SSG A + + GL HT I++ LYGGT
Sbjct: 58 LQHQIGKLYRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHT-PTIIAGDDLYGGTQRL 116
Query: 117 FKVAFKRLGIEARFVDGDKPEDFEKLFD--EKTKALYLESIGNPKYNVPDFEKIVAVAH- 173
++ + VD E F+ +F +K + LES NP V D +I+
Sbjct: 117 LNFFKQQSHAVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKC 176
Query: 174 -KHGIPVVVDNTFGAGGFFCQPIKY--GADIVTHSATKWXXXXXXXXXXXXXDSGKFPWK 230
VVVDNT G C P++ G D+V SATK+
Sbjct: 177 ISPDTTVVVDNTM-MSGLNCNPLQLNPGCDVVYESATKYL-------------------- 215
Query: 231 DYPEKFPQFSQPSEGYHGLIFNDAFGPAAFIGHVRTELLRDLGPVLSPFAGFLLLQGLET 290
G+H L+ I ++ G LSP +LL++GL+T
Sbjct: 216 -------------NGHHDLMGGVIISKTPEIASKLYFVINSTGAGLSPMDSWLLVRGLKT 262
Query: 291 LSLRGERHGSNALKLAQYLESS--------PYVSWVSYPGLPSHSHHENAKKYLENGFGG 342
L +R + NA+ LA +LE+S + + GL S+ + K + NG G
Sbjct: 263 LGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVGLRSNPDFKLHKSF-NNGPGA 321
Query: 343 VLSFGVKDLPNASEESDPFKASGAQVVDNLKLA--SNLANVGDSKTLVIAPYFTTHQQLT 400
VLSF E+ F+ S ++V + KL+ + + G +L+ P +H +
Sbjct: 322 VLSF----------ETGSFEHS-KRLVSSKKLSIWAVTVSFGCVNSLLSMPCKMSHASID 370
Query: 401 DEEKLASGVTKDLIRVSVGTEFIDDIIADFEAS 433
E + +DL+R+ G E I D+ D A+
Sbjct: 371 PELRKERDFPEDLVRLCCGIENIVDLKKDLLAA 403
>YFR055w [E] KOG0053 Cystathionine beta-lyases/cystathionine gamma-synthases
Length = 340
Score = 79.7 bits (195), Expect = 8e-15
Identities = 49/158 (31%), Positives = 75/158 (47%), Gaps = 1/158 (0%)
Query: 52 GYIYSRIMNPTLDVLEKRXXXXXXXXXXXXTSSGQAAQTLAVTGLAHTGDNIVSTSFLYG 111
G Y +PT+D LE ++SG + +LA+ L+ GD+I+ T +Y
Sbjct: 53 GRFYGTAGSPTIDNLENAWTHLTGGAGTVLSASGLGSISLALLALSKAGDHILMTDSVYV 112
Query: 112 GTYNQFKVAFKRLGIEARFVDGDKPEDFEKLFDEKTKALYLESIGNPKYNVPDFEKIVAV 171
T + G+E + D +D EKL T ++LES G+ V D +V+V
Sbjct: 113 PTRMLCDGLLAKFGVETDYYDPSIGKDIEKLVKPNTTVIFLESPGSGTMEVQDIPALVSV 172
Query: 172 AHKHGIPVVVDNTFGAGGFFCQPIKYGADIVTHSATKW 209
A KHGI ++DNT+ FF +G DI + TK+
Sbjct: 173 AKKHGIKTILDNTWATPLFF-DAHAHGIDISVEAGTKY 209
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.317 0.136 0.402
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,545,645
Number of Sequences: 60738
Number of extensions: 1118340
Number of successful extensions: 2406
Number of sequences better than 1.0e-05: 15
Number of HSP's better than 0.0 without gapping: 12
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 2342
Number of HSP's gapped (non-prelim): 28
length of query: 444
length of database: 30,389,216
effective HSP length: 110
effective length of query: 334
effective length of database: 23,708,036
effective search space: 7918484024
effective search space used: 7918484024
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)