ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIV1169 good K KOG3233 Transcription RNA polymerase III, subunit C34
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIV1169 385445 384357 -363
(363 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YNR003c [K] KOG3233 RNA polymerase III subunit C34 410 e-114
SPCC290.02 [K] KOG3233 RNA polymerase III subunit C34 186 4e-47
Hs5454020 [K] KOG3233 RNA polymerase III subunit C34 135 1e-31
Hs18592434 [K] KOG3233 RNA polymerase III subunit C34 132 8e-31
7300836 [K] KOG3233 RNA polymerase III subunit C34 132 8e-31
ECU10g0210 [K] KOG3233 RNA polymerase III subunit C34 114 3e-25
CE14750 [K] KOG3233 RNA polymerase III subunit C34 103 5e-22
>YNR003c [K] KOG3233 RNA polymerase III subunit C34
Length = 317
Score = 410 bits (1055), Expect = e-114
Identities = 202/317 (63%), Positives = 255/317 (79%), Gaps = 5/317 (1%)
Query: 52 MNSLFNSTIKLSDPARELHEKMCSQETGKLFSQKELTSMLDNCSLSDLMQYVQELLDKNL 111
M+ + + ++LSD A+ LH +M S+ G LF+Q+EL + SL+DLM VQELLDKNL
Sbjct: 1 MSGMIENGLQLSDNAKTLHSQMMSKGIGALFTQQELQKQMGIGSLTDLMSIVQELLDKNL 60
Query: 112 LKLVKQNKELKFQAVDAAEAEKKSGMSSDEALVYSYIEASGREGIWTKTIKAKTNLHQHV 171
+KLVKQN ELKFQ V +EA+KK+ MS++EALVYSYIEASGREGIW+KTIKA+TNLHQHV
Sbjct: 61 IKLVKQNDELKFQGVLESEAQKKATMSAEEALVYSYIEASGREGIWSKTIKARTNLHQHV 120
Query: 172 VLKCLKSLESQRYVKSVKSVKYPTRKIYMLYNLQPSIDVTGGPWFTDSELDVEFINSLLT 231
VLKCLKSLESQRYVKSVKSVK+PTRKIYMLY+LQPS+D+TGGPWFTD ELD+EFINSLLT
Sbjct: 121 VLKCLKSLESQRYVKSVKSVKFPTRKIYMLYSLQPSVDITGGPWFTDGELDIEFINSLLT 180
Query: 232 IVWRFTAERTYPNGFNNFSDENGRDALYSSNVKSYTTIEEILEFISESGISTEQLTKPDI 291
IVWRF +E T+PNGF NF + ++ Y+ NVK+Y+T +EILEFI+ + ++ +LT +I
Sbjct: 181 IVWRFISENTFPNGFKNFENGPKKNVFYAPNVKNYSTTQEILEFITAAQVANVELTPSNI 240
Query: 292 RSLCEVLVYDDKLEKVSFDCFRVTLQSVLQMTQPVGGQQSSKR-----EEYSIFSHGNSM 346
RSLCEVLVYDDKLEKV+ DC+RVTL+S+LQM Q G ++ + EE+SIF++
Sbjct: 241 RSLCEVLVYDDKLEKVTHDCYRVTLESILQMNQGEGEPEAGNKALEDEEEFSIFNYFKMF 300
Query: 347 AASSSDKDVLYFDEWTL 363
AS DK+V+YFDEWT+
Sbjct: 301 PASKHDKEVVYFDEWTI 317
>SPCC290.02 [K] KOG3233 RNA polymerase III subunit C34
Length = 301
Score = 186 bits (473), Expect = 4e-47
Identities = 104/263 (39%), Positives = 157/263 (59%), Gaps = 8/263 (3%)
Query: 66 ARELHEKMCSQETGKLFSQKELTSMLDNCSLSDLMQYVQELLDKNLLKLVKQNKELKFQA 125
A+ ++E Q L Q + ++ + S++DL + LL + LL ++Q L ++A
Sbjct: 12 AKVIYEHCLKQIPNSLSQQDLVEAIGASISVNDLSSALNILLSRRLLDPLRQGNVLVYRA 71
Query: 126 VDAAEAEKKSGMSSDEALVYSYIEASGREGIWTKTIKAKTNLHQHVVLKCLKSLESQRYV 185
V EA+ S M DE +VYS+I+ SG EGIW KT+ +TNLH VV +CLKSLES+ V
Sbjct: 72 VRLDEAKTVSTMEGDEQIVYSFIKNSGNEGIWRKTLTLRTNLHVSVVDRCLKSLESKNLV 131
Query: 186 KSVKSVKYPTRKIYMLYNLQPSIDVTGGPWFTDSELDVEFINSLLTIVWRFTAERTYPNG 245
KS+KSVK PTRKIYMLY+L PS ++TGGPWFTD ELDVEFI +L +++R+ +++P
Sbjct: 132 KSIKSVKNPTRKIYMLYDLVPSTELTGGPWFTDQELDVEFIENLKKVIYRYVHSKSFPPK 191
Query: 246 FNNFSDENGRDALYSSNVKSYTTIEEILEFISESGISTEQLTKPDIRSLCEVLVYDDKLE 305
G D ++ Y T +I ++ + I+ L+ ++ SL +VL+YD K+E
Sbjct: 192 ----KAAMGPDLVWGPEYNGYPTALQIHNWLRSTNITKVDLSLANVISLVDVLIYDGKVE 247
Query: 306 K----VSFDCFRVTLQSVLQMTQ 324
K S+ RV +++ T+
Sbjct: 248 KRSDGASYRAIRVNNENIDAFTE 270
>Hs5454020 [K] KOG3233 RNA polymerase III subunit C34
Length = 317
Score = 135 bits (339), Expect = 1e-31
Identities = 77/230 (33%), Positives = 124/230 (53%), Gaps = 7/230 (3%)
Query: 103 VQELLDKNLLKLVKQNKELKFQAVDAAEAEKKSGMSSDEALVYSYIEASGREGIWTKTIK 162
+ LL L L++ N L ++ D+ A K G + E LVY IE +G +GIW++ I+
Sbjct: 54 INRLLSMGQLDLLRSNTGLLYRIKDSQNAGKMKGSDNQEKLVYQIIEDAGNKGIWSRDIR 113
Query: 163 AKTNLHQHVVLKCLKSLESQRYVKSVKSVKYPTRKIYMLYNLQPSIDVTGGPWFTDSELD 222
K+NL + K LK+LES++ +K+VKSV +K+YMLYNLQP VTGG W++D + +
Sbjct: 114 YKSNLPLTEINKILKNLESKKLIKAVKSVAASKKKVYMLYNLQPDRSVTGGAWYSDQDFE 173
Query: 223 VEFINSLLTIVWRFTAERTYPNGFNNFSDENGRDALYSSNVKSYTTIEEILEFISESGIS 282
EF+ L ++F + + E+ ++ + N S+ + E+ ++I E GIS
Sbjct: 174 SEFVEVLNQQCFKFLQSKA------ETARESKQNPMIQRN-SSFASSHEVWKYICELGIS 226
Query: 283 TEQLTKPDIRSLCEVLVYDDKLEKVSFDCFRVTLQSVLQMTQPVGGQQSS 332
+L+ DI ++ L+YD K+E C R + V G QS+
Sbjct: 227 KVELSMEDIETILNTLIYDGKVEMTIIACKRRHSWQCRWTHETVQGSQSN 276
>Hs18592434 [K] KOG3233 RNA polymerase III subunit C34
Length = 316
Score = 132 bits (332), Expect = 8e-31
Identities = 74/217 (34%), Positives = 120/217 (55%), Gaps = 7/217 (3%)
Query: 103 VQELLDKNLLKLVKQNKELKFQAVDAAEAEKKSGMSSDEALVYSYIEASGREGIWTKTIK 162
+ LL L L++ N L ++ D+ A K G + E LVY IE +G +GIW++ I+
Sbjct: 54 INRLLSMGQLDLLRSNTGLLYRIKDSQNAGKMKGSDNQEKLVYQIIEDAGNKGIWSRDIR 113
Query: 163 AKTNLHQHVVLKCLKSLESQRYVKSVKSVKYPTRKIYMLYNLQPSIDVTGGPWFTDSELD 222
K+NL + K LK+LES++ +K+VKSV +K+YMLYNLQP VTGG W++D + +
Sbjct: 114 YKSNLPLTEINKILKNLESKKLIKAVKSVAASKKKVYMLYNLQPDRSVTGGAWYSDQDFE 173
Query: 223 VEFINSLLTIVWRFTAERTYPNGFNNFSDENGRDALYSSNVKSYTTIEEILEFISESGIS 282
EF+ L ++F + + E+ ++ + N S+ + E+ ++I E GIS
Sbjct: 174 SEFVEVLNQQCFKFLQSKA------ETARESKQNPMIQRN-SSFASSHEVWKYICELGIS 226
Query: 283 TEQLTKPDIRSLCEVLVYDDKLEKVSFDCFRVTLQSV 319
+L+ DI ++ L+YD K+E T+ SV
Sbjct: 227 KVELSMEDIETILNTLIYDGKVEMTIIAAKEGTVGSV 263
>7300836 [K] KOG3233 RNA polymerase III subunit C34
Length = 293
Score = 132 bits (332), Expect = 8e-31
Identities = 74/226 (32%), Positives = 128/226 (55%), Gaps = 14/226 (6%)
Query: 86 ELTSMLDNCSLSDLMQYVQELLDKNLLKLVKQNKELKFQAVDAAEAEKKSGMSSD----E 141
+LT L + + ++ + LL + ++++K+ ++L ++A D EKKS + D E
Sbjct: 24 DLTKALPDVPAATRVEALNILLQEGGIEILKKGEKLVYRAKDP---EKKSALPKDADNEE 80
Query: 142 ALVYSYIEASGREGIWTKTIKAKTNLHQHVVLKCLKSLESQRYVKSVKSVKYPTRKIYML 201
+VY +E G +GIW + I+ K+NL+ + K LK+LE+++ +K+VKSV +K+YML
Sbjct: 81 KVVYGIVEEGGNKGIWIRDIRMKSNLNMIQLNKILKNLETKKLIKAVKSVNASKKKVYML 140
Query: 202 YNLQPSIDVTGGPWFTDSELDVEFINSLLTIVWRFTAERTYPNGFNNFSDENGRDALYSS 261
YNL+P + +TGG W+ D + +VEF++ L RF S E R+ +
Sbjct: 141 YNLEPDLSITGGAWYQDQDFEVEFVDVLNQQCLRFLQ-------MKRDSAEKKREGPLAF 193
Query: 262 NVKSYTTIEEILEFISESGISTEQLTKPDIRSLCEVLVYDDKLEKV 307
S T+ E+ +FIS+ GIS L + D+ ++ + +VYD E+V
Sbjct: 194 KQMSCCTVNEVQKFISDLGISKVNLAEADLETILKTVVYDGNAERV 239
>ECU10g0210 [K] KOG3233 RNA polymerase III subunit C34
Length = 236
Score = 114 bits (284), Expect = 3e-25
Identities = 73/228 (32%), Positives = 124/228 (54%), Gaps = 29/228 (12%)
Query: 84 QKELTSMLDNCSLSDLMQYVQELLDKNLLKLVKQNKELKFQAVDAAEAEKKSGMSSD--E 141
++EL+S S +D+ + + L + + L + L + K S ++ D E
Sbjct: 18 EEELSSEFPQMSKADVAKELNACLKRQEISLFRDKGVLYY---------KPSPINVDDYE 68
Query: 142 ALVYSYIEASGREGIWTKTIKAKTNLHQHVVLKCLKSLESQRYVKSVKSVKYPTRKIYML 201
+Y+ + SG EG+W K IK KTN+ ++V K L+S+ES+R +KSVK +K RK+Y+L
Sbjct: 69 LTIYNLVSQSGGEGVWLKVIKDKTNMPHNLVGKVLRSMESKRIIKSVKCLK-NNRKVYVL 127
Query: 202 YNLQPSIDVTGGPWFTDSELDVEFINSLLTIVWRFTAERTYPNGFNNFSDENGRDAL--Y 259
Y+ PS ++TGG WF D+++DVE + +L I+ F + GR+ L Y
Sbjct: 128 YDQVPSEEITGGTWFHDNDVDVECVARILEIIELFLEKNL-----------AGREELPKY 176
Query: 260 SSNVKSYTTIEEILEFISESGISTEQLTKPDIRSLCEVLVYDDKLEKV 307
N T+E+I+ ++ I + L D+ +L ++LV+D K+EK+
Sbjct: 177 EDN----PTLEDIMNYVRNVNILSIPLRLDDLETLADILVFDGKVEKL 220
>CE14750 [K] KOG3233 RNA polymerase III subunit C34
Length = 296
Score = 103 bits (256), Expect = 5e-22
Identities = 63/222 (28%), Positives = 118/222 (52%), Gaps = 13/222 (5%)
Query: 91 LDNCSLSDLMQYVQELLDKNLLKLVKQNKELKFQAVDAAEAEKKSGMSS------DEALV 144
+D +L+ + + + + + + + +K+L Q K S +E ++
Sbjct: 29 IDMDALTSMTPGLPQTVRQTAINSLLSSKKLAIQQAPGGVLRLKVNTSEQIAGTEEEQVI 88
Query: 145 YSYIEASGREGIWTKTIKAKTNLHQHVVLKCLKSLESQRYVKSVKSVKYPTRKIYMLYNL 204
YS IE S GIW K ++ + L+Q + K LKSLE+++ +K++K+V TRK Y+L+++
Sbjct: 89 YSLIEESKTRGIWIKELREGSGLNQLQLRKTLKSLETKKLIKTIKAVG-TTRKCYILFSI 147
Query: 205 QPSIDVTGGPWFTDSELDVEFINSLLTIVWRFTAERTYPNGFNNFSDENGRDALYSSNVK 264
+P + +TGG +++D +LD E IN+L+++ + A R + DEN + +
Sbjct: 148 EPDMSLTGGTFYSDQQLDSELINTLISVCGSYAASRR-----KHAIDENPNN-IQMQREA 201
Query: 265 SYTTIEEILEFISESGISTEQLTKPDIRSLCEVLVYDDKLEK 306
SY +EI +FI+E + L+ D+ + EV V D +E+
Sbjct: 202 SYIRPQEIAQFITEKRVLNVPLSLEDLERILEVAVLDGTIER 243
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.315 0.131 0.365
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,873,277
Number of Sequences: 60738
Number of extensions: 796661
Number of successful extensions: 2463
Number of sequences better than 1.0e-05: 7
Number of HSP's better than 0.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 1
Number of HSP's that attempted gapping in prelim test: 2447
Number of HSP's gapped (non-prelim): 8
length of query: 363
length of database: 30,389,216
effective HSP length: 108
effective length of query: 255
effective length of database: 23,829,512
effective search space: 6076525560
effective search space used: 6076525560
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)