ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIV1198 check: MH T KOG0230 Signal transduction mechanisms Phosphatidylinositol-4-phosphate 5-kinase and related FYVE finger-containing proteins
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIV1198 390602 396763 2054
(2054 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YFR019w [T] KOG0230 Phosphatidylinositol-4-phosphate 5-kinase an... 1725 0.0
SPBC6B1.11c [T] KOG0230 Phosphatidylinositol-4-phosphate 5-kinas... 454 e-127
At4g33240 [T] KOG0230 Phosphatidylinositol-4-phosphate 5-kinase ... 305 5e-82
At3g14270 [T] KOG0230 Phosphatidylinositol-4-phosphate 5-kinase ... 305 5e-82
At1g71010 [T] KOG0230 Phosphatidylinositol-4-phosphate 5-kinase ... 293 2e-78
Hs14729948 [T] KOG0230 Phosphatidylinositol-4-phosphate 5-kinase... 286 2e-76
At1g34260 [T] KOG0230 Phosphatidylinositol-4-phosphate 5-kinase ... 251 1e-65
CE18979 [T] KOG0230 Phosphatidylinositol-4-phosphate 5-kinase an... 229 3e-59
7302711 [T] KOG0230 Phosphatidylinositol-4-phosphate 5-kinase an... 226 4e-58
YJL014w [O] KOG0364 Chaperonin complex component TCP-1 gamma sub... 91 2e-17
SPBC1A4.08c [O] KOG0364 Chaperonin complex component TCP-1 gamma... 87 3e-16
At5g26360 [O] KOG0364 Chaperonin complex component TCP-1 gamma s... 85 1e-15
Hs5174727 [O] KOG0364 Chaperonin complex component TCP-1 gamma s... 84 2e-15
Hs20539011 [O] KOG0364 Chaperonin complex component TCP-1 gamma ... 84 2e-15
7300184 [O] KOG0364 Chaperonin complex component TCP-1 gamma sub... 83 4e-15
At1g10900 [T] KOG0229 Phosphatidylinositol-4-phosphate 5-kinase 79 6e-14
ECU10g0240 [O] KOG0364 Chaperonin complex component TCP-1 gamma ... 76 6e-13
CE25900 [O] KOG0364 Chaperonin complex component TCP-1 gamma sub... 76 6e-13
ECU10g0630 [O] KOG0361 Chaperonin complex component TCP-1 eta su... 75 1e-12
At1g60890 [T] KOG0229 Phosphatidylinositol-4-phosphate 5-kinase 75 1e-12
Hs6857820 [T] KOG0229 Phosphatidylinositol-4-phosphate 5-kinase 74 2e-12
7304346 [T] KOG0229 Phosphatidylinositol-4-phosphate 5-kinase 74 2e-12
Hs21322230 [T] KOG0229 Phosphatidylinositol-4-phosphate 5-kinase 73 4e-12
At3g09920 [T] KOG0229 Phosphatidylinositol-4-phosphate 5-kinase 73 4e-12
Hs4505819 [T] KOG0229 Phosphatidylinositol-4-phosphate 5-kinase 72 1e-11
Hs4505815 [T] KOG0229 Phosphatidylinositol-4-phosphate 5-kinase 69 8e-11
At2g41210 [T] KOG0229 Phosphatidylinositol-4-phosphate 5-kinase 69 1e-10
YJL111w [O] KOG0361 Chaperonin complex component TCP-1 eta subun... 67 2e-10
CE11121 [T] KOG0229 Phosphatidylinositol-4-phosphate 5-kinase 67 2e-10
7291493 [T] KOG0229 Phosphatidylinositol-4-phosphate 5-kinase 67 2e-10
Hs4505817 [T] KOG0229 Phosphatidylinositol-4-phosphate 5-kinase 67 3e-10
Hs20550114 [T] KOG0229 Phosphatidylinositol-4-phosphate 5-kinase 66 7e-10
At3g56960 [T] KOG0229 Phosphatidylinositol-4-phosphate 5-kinase 66 7e-10
At3g11830 [O] KOG0361 Chaperonin complex component TCP-1 eta sub... 66 7e-10
Hs16193739 [T] KOG0229 Phosphatidylinositol-4-phosphate 5-kinase 65 9e-10
7301552 [R] KOG1819 FYVE finger-containing proteins 65 1e-09
At1g77740 [T] KOG0229 Phosphatidylinositol-4-phosphate 5-kinase 65 1e-09
Hs14745097 [T] KOG0229 Phosphatidylinositol-4-phosphate 5-kinase 64 3e-09
At1g21980 [T] KOG0229 Phosphatidylinositol-4-phosphate 5-kinase 64 3e-09
CE06781 [TU] KOG1818 Membrane trafficking and cell signaling pro... 63 4e-09
SPBC25H2.12c [O] KOG0361 Chaperonin complex component TCP-1 eta ... 62 7e-09
CE20122 [TU] KOG1786 Lysosomal trafficking regulator LYST and re... 62 7e-09
At3g20050 [O] KOG0360 Chaperonin complex component TCP-1 alpha s... 62 7e-09
Hs5453607 [O] KOG0361 Chaperonin complex component TCP-1 eta sub... 62 1e-08
Hs22044271 [TU] KOG1786 Lysosomal trafficking regulator LYST and... 62 1e-08
Hs13376757 [R] KOG1729 FYVE finger containing protein 61 2e-08
Hs4758528 [TU] KOG1818 Membrane trafficking and cell signaling p... 60 3e-08
At2g26420 [T] KOG0229 Phosphatidylinositol-4-phosphate 5-kinase 60 3e-08
At3g07960 [T] KOG0229 Phosphatidylinositol-4-phosphate 5-kinase 60 5e-08
At1g20110 [R] KOG1729 FYVE finger containing protein 60 5e-08
YIL142w [O] KOG0363 Chaperonin complex component TCP-1 beta subu... 59 6e-08
YGL023c [R] KOG1729 FYVE finger containing protein 59 6e-08
SPBC36B7.05c [R] KOG1729 FYVE finger containing protein 59 1e-07
YDR313c [R] KOG1729 FYVE finger containing protein 58 1e-07
Hs6552339 [V] KOG1841 Smad anchor for receptor activation 58 2e-07
Hs6552337 [V] KOG1841 Smad anchor for receptor activation 58 2e-07
Hs4759060 [V] KOG1841 Smad anchor for receptor activation 58 2e-07
CE01234 [O] KOG0359 Chaperonin complex component TCP-1 zeta subu... 58 2e-07
7299092 [O] KOG0361 Chaperonin complex component TCP-1 eta subun... 58 2e-07
7290174 [R] KOG1729 FYVE finger containing protein 58 2e-07
ECU06g0510 [O] KOG0359 Chaperonin complex component TCP-1 zeta s... 57 2e-07
CE27279 [T] KOG0229 Phosphatidylinositol-4-phosphate 5-kinase 57 2e-07
SPAC19G12.14 [T] KOG0229 Phosphatidylinositol-4-phosphate 5-kinase 57 3e-07
Hs10863893 [IU] KOG4471 Phosphatidylinositol 3-phosphate 3-phosp... 57 3e-07
YDR208w [T] KOG0229 Phosphatidylinositol-4-phosphate 5-kinase 57 4e-07
CE19557 [R] KOG1819 FYVE finger-containing proteins 57 4e-07
At3g43230 [S] KOG1843 Uncharacterized conserved protein 56 5e-07
Hs14784247 [R] KOG1811 Predicted Zn2+-binding protein contains F... 56 7e-07
7303510 [O] KOG0357 Chaperonin complex component TCP-1 epsilon s... 56 7e-07
Hs20543659 [TU] KOG1818 Membrane trafficking and cell signaling ... 55 9e-07
SPAC1420.02c [O] KOG0357 Chaperonin complex component TCP-1 epsi... 55 1e-06
Hs7662048 [V] KOG1841 Smad anchor for receptor activation 55 1e-06
Hs13470092 [R] KOG1729 FYVE finger containing protein 55 2e-06
SPAC19A8.05c [TU] KOG1818 Membrane trafficking and cell signalin... 54 2e-06
CE28255 [O] KOG0361 Chaperonin complex component TCP-1 eta subun... 54 3e-06
Hs8922921 [R] KOG1729 FYVE finger containing protein 54 3e-06
Hs13375827 [R] KOG1729 FYVE finger containing protein 54 3e-06
Hs10835109 [IU] KOG4471 Phosphatidylinositol 3-phosphate 3-phosp... 53 4e-06
7301558_1 [T] KOG4381 RUN domain-containing protein 53 4e-06
Hs16159222 [O] KOG0357 Chaperonin complex component TCP-1 epsilo... 53 6e-06
7297349 [R] KOG1842 FYVE finger-containing protein 52 8e-06
7291295 [V] KOG1841 Smad anchor for receptor activation 52 8e-06
Hs21245128 [T] KOG4424 Predicted Rho/Rac guanine nucleotide exch... 52 1e-05
At1g01460 [T] KOG0229 Phosphatidylinositol-4-phosphate 5-kinase 52 1e-05
>YFR019w [T] KOG0230 Phosphatidylinositol-4-phosphate 5-kinase and related
FYVE finger-containing proteins
Length = 2278
Score = 1725 bits (4467), Expect = 0.0
Identities = 1005/2271 (44%), Positives = 1353/2271 (59%), Gaps = 326/2271 (14%)
Query: 53 TTTEVDTNPVLSDM---QISAPIGLELTNERRESSNGDDVQDNRMTIRSNIALPLPKLTK 109
TTT++ TNP+LS++ +IS P + S + + +N + + K
Sbjct: 56 TTTDLVTNPILSNISVPKISPPTSSSIATATSTSHVTGTASHSNIKANANTSTSVNK--- 112
Query: 110 DAETPNLHSESLQRTLTNDSTTDFDVLSKTDSENPSLGQGEQPKSLHFSLGNSARTKRSS 169
NL TT + S T PS + + SL + N + KRSS
Sbjct: 113 ----KNL-----------PPTTSGRIPSSTIKRYPS--RYKPSHSLQLPIKNDSNFKRSS 155
Query: 170 IYESKSTVTAIPIRTPSNSNRNIHAYNHPHSYXXXXXX---------XXXXXXXXXXXXX 220
IY SKSTVTAIPIR +NR I N SY
Sbjct: 156 IYASKSTVTAIPIR----NNRPISMQN---SYARTPDSDHDDVGDEVSSIKSASSSLTAS 208
Query: 221 XXXXFLFGFYDXXXXXXXXXXNILSKEYWMKDESAKECFNCAKPFTTFRRKHHCRICGQI 280
FLF FY+ +LSKEYWMKDES+KECF+C K F TFRRKHHCRICGQI
Sbjct: 209 LSKSFLFAFYNNRKKDKTSNNGVLSKEYWMKDESSKECFSCGKTFNTFRRKHHCRICGQI 268
Query: 281 FCSSCSFLITGESFGYSGRMRICGKCYEHSMNYXXXXXXXXXXXI--------------- 325
FCSSC+ LI G+ FG +MR+C CYEH+ Y +
Sbjct: 269 FCSSCTLLIDGDRFGCHAKMRVCYNCYEHADTYEDSSDEENDSTMQLNEPRSRSRSRSSN 328
Query: 326 -----------------------IHDQVSSRNI---DDDAPSLNNDDIQSILTNVDDHKV 359
+HD V++ + ++ LN+DD+QSI+T+ +D K+
Sbjct: 329 TNPYSHSHSHLHLISQDNHNGTDLHDPVAATDNPQQQNEVYLLNDDDVQSIMTSGEDSKL 388
Query: 360 HISTPEPLPRMAIPATKQGESLEISFHSKANNH-GYRKSRPRR-----GTQDRYALHNLE 413
ISTP P P+MAIPATKQG SLEISF S+ + Y+ P R RY + +++
Sbjct: 389 FISTPPPPPKMAIPATKQGGSLEISFDSENDRALHYQDDNPGRHHHLDSVPTRYTIRDMD 448
Query: 414 KLSPIP-------QEHADSKHSP-----------ERSLLINKNSQHGHMRPSFS---SYL 452
+S + H ++ +S S N NS P+ S S
Sbjct: 449 NISHYDTNSNSTLRPHYNTNNSTITINNLNNTTSNNSNYNNTNSNSNINNPAHSLRRSIF 508
Query: 453 SQKNGSALRKDTPNNP-----------------NVMKTLANNNFKFEFNYDM-------- 487
+ +++ KD+ N+ ++ A+ N+KF+FNY+
Sbjct: 509 HYVSSNSVNKDSNNSSATPASSAQSSSILDPANRIIGNYAHRNYKFKFNYNSKGPSQQND 568
Query: 488 -----------NNFQSYLQKERQPAGLSESKQLPL----------------LSNRYSSPN 520
NN + +G++++ +P L+ S+
Sbjct: 569 TANGNNDNNNNNNNNNNNNNNNSASGIADNNNIPSNDNGTTFTLDKKKRNPLTKSKSTSA 628
Query: 521 FQXXXXXXXXXXXXXXXXXLYTALNETHKHDKNRSLTMRNSTNSSQRAEASLXXXXXXXX 580
+ +Y+ LN+ HK D N +MRNST S QRA+ASL
Sbjct: 629 YLEYPLNEEDSSEDEGSMSIYSVLNDDHKTD-NPIRSMRNSTKSFQRAQASLQRMRFRRK 687
Query: 581 XXXXPGPINNNGR--GEFSFMNLSAPNLVTVVNNDLVF----------SKNQNPQLQKQK 628
P N+ + +F+ S PNL++VV++D ++ S + +L +K
Sbjct: 688 SKSKHFPNNSKSSIYRDLNFLTNSTPNLLSVVSDDNLYDDSSPLQDKASSSAASRLTDRK 747
Query: 629 YD----SNSKDARKSILNSSTWRRISL--------DKREELNDVCKLHLEALLQQALTDQ 676
+ SN+ S +N+ W+RI+ +K+ ELN+V LH+ ALL+Q L DQ
Sbjct: 748 FSNSSGSNNNSNSNSNINTDPWKRIASISGFKLKKEKKRELNEVSLLHMHALLKQLLNDQ 807
Query: 677 EIPGEGDWIAIFNKMIGQIQGIPLDARKAGDLDFKQQHVKIKRLPGGSVLDSMILNGVLY 736
EI +WI + + + ++ L+AR LDF+Q +VKIKR+ GGS +S ++GV++
Sbjct: 808 EISNLQEWITLLDGALRKVLRTILNARDLNTLDFRQTYVKIKRISGGSPQNSEYIDGVVF 867
Query: 737 SKGLPLKTMPRVVMNPRILLIMFPLEYQKHNNHVISIESVVAQEKEYLKKLVLRLQSLNP 796
SK LP KTMPR + NPRILLIMFPLEYQK+NNH +SIESV QE+EYL KLV RL+SL+P
Sbjct: 868 SKALPSKTMPRHLKNPRILLIMFPLEYQKNNNHFLSIESVFRQEREYLDKLVSRLKSLHP 927
Query: 797 DIILTGTSASGYALQLFQEVGIVVQCNVKPQVIERISRFTGCDIVITMDKLSSNIKLGTC 856
DII G + SGYAL+L + GIVVQ N+KPQVIERI++ T DI I++DKL++NIK+G C
Sbjct: 928 DIIYVGANVSGYALELLNDSGIVVQFNMKPQVIERIAKLTEADIAISVDKLATNIKMGEC 987
Query: 857 ERFEVRTYIYGNLSKNYTFITGCKTQAGITLVLRGNTSEVLRKVKDVAEFVAYAVFSMKL 916
E FEV++YIYGN+SK YTF+ GC + G T++LRG++ E LRK+K V+EF+ YA+FS+KL
Sbjct: 988 ETFEVKSYIYGNISKTYTFLRGCNPELGGTILLRGDSLENLRKIKQVSEFMVYAIFSLKL 1047
Query: 917 ESSFFNDNFLQLNIEAYKHIQLLKKQNESFTGFFADFIEKFNRRILSVSPIVEFPVPYLL 976
ESSFFNDNF+QL+ + Y + K+ + F G+FADF+ KFN RIL+VSP V+FP+P+LL
Sbjct: 1048 ESSFFNDNFIQLSTDVYLK-RAESKKLQVFEGYFADFLIKFNNRILTVSPTVDFPIPFLL 1106
Query: 977 QKARDVEQQLIEKTALVKKLQDCAEILEYKDSIDLSKMQ-------LETALTQRDFKYLI 1029
+KAR +E++LIE+ I +Y+ DL + LE+ +T++ LI
Sbjct: 1107 EKARGLEKKLIER------------INQYESESDLDRQTQLNMLQGLESTITKKHLGNLI 1154
Query: 1030 GFINNKECDALKLQFETLKKKWEIYSSLSHNMLGTGPHQSISVLYSVISRKTTTPCIGPE 1089
F++ E + L+L+F+ ++WE+ S S N+LGTG HQSI+VLYS++S KT TPC+GP+
Sbjct: 1155 KFLHEMEIENLELEFQKRSRQWEVSYSSSQNLLGTGSHQSITVLYSMVSTKTATPCVGPQ 1214
Query: 1090 IVTIDFFWENDISIGQFIENVVATAFRPCADGCGGLMIDHYRSYAHGNGKLDVIIERLQS 1149
IVTID+FW++DISIGQFIENVV TA PC GC GL +DHYRSY HG+GK+DV+IE+ Q+
Sbjct: 1215 IVTIDYFWDSDISIGQFIENVVGTARYPCQQGCNGLYLDHYRSYVHGSGKVDVLIEKFQT 1274
Query: 1150 KMPMLKNLILTWSYCKKCGLSSPTLQLSEKSWNYSLGKYLELMFWSSPKNINSIGNCTHD 1209
++P LK++ILTWSYCKKCG S+P LQ+SEK+WN+S GKYLE+MFWS ++ IG C HD
Sbjct: 1275 RLPKLKDIILTWSYCKKCGTSTPILQISEKTWNHSFGKYLEVMFWSYKDSVTGIGKCPHD 1334
Query: 1210 VAKDHLKYFSLNDLVVRMEYSGIDVHELITPTATITWNPGKDIKLKVELYYQILEKIDAF 1269
KDH+KYF NDLVVR+EYS ++VHELITP I W P DIKLKVELYY+ILEKI+ F
Sbjct: 1335 FTKDHVKYFGYNDLVVRLEYSDLEVHELITPPRKIKWKPHIDIKLKVELYYKILEKINNF 1394
Query: 1270 YGSVLERLNKLKIDSINDLKLNEAKERIVQLKVLVEDEKSTLGANMETIYTGLEGDQHLQ 1329
YGSVL RL ++K+DS+ K+ + +I++LK +E+ + +++T Y DQHL
Sbjct: 1395 YGSVLSRLERIKLDSMTKDKVLSGQAKIIELKSNATEEQKLMLQDLDTFYADSPCDQHLP 1454
Query: 1330 LNSIVRALHDNAAGWDNEFVEFEKEFLPTEKDIARITALQLKKMFTDFN-KMTED----- 1383
LN ++++L+D A W++ F F K +LP+E DI+RITA QLKK+F D + K +ED
Sbjct: 1455 LNLVIKSLYDKAVNWNSTFAIFAKSYLPSETDISRITAKQLKKLFYDSSRKDSEDKKSLH 1514
Query: 1384 ----------------NGIKEINGEDAEAEEKSKCMDTTSEEQRS---DEESDASPPKPK 1424
G+K++ +++ ++ D T+E Q + D +P P
Sbjct: 1515 DEKAKTRKPEKNELPLEGLKDVEKPKIDSKNTTENRDRTNEPQNAVTITTFKDDTPIIPT 1574
Query: 1425 SVQNAELPLIKSATTNTFSEETIGKVTGPRKQSMT------SSLDRNLIRKNSNNST--- 1475
S + L + SA++ + S + P +S T R IRK S++S+
Sbjct: 1575 S-GTSHLTVTPSASSVSSSLTPQTEERPPISRSGTGISMTHDKSTRPNIRKMSSDSSLCG 1633
Query: 1476 YTQSSKDRNSDTKVGQLANFFDQIHFDSVTREFELQREMERLHMNKTKYQAMRAKSLKPL 1535
+ + + + KV +LA FFDQ+HFD++++EFEL+RE ERL +NK KYQA+R ++ P+
Sbjct: 1634 LASLANEYSKNNKVSKLATFFDQMHFDALSKEFELERERERLQLNKDKYQAIRLQTSTPI 1693
Query: 1536 VEIYKNVQDAVEEPINVDKGAKNQNS--LVNSDNTQGTYDTAK-----PLNKGLENELEQ 1588
VEIYKNV+DAV+EP++ N +S + + G + A L++ LE ELE
Sbjct: 1694 VEIYKNVKDAVDEPLHSRSSGNNLSSANVKTLEAPVGEHSRANNCNPPNLDQNLETELEN 1753
Query: 1589 SINQWSERVLQ-----------------NQTGDQPVDITAKPSN---EPLPPVTTITNAN 1628
SI+QW E +L +T + P I + N EPLPPV T T N
Sbjct: 1754 SISQWGENILNPSGKTTASTHLNSKPVVKETSENPKSIVRESDNSKSEPLPPVITTTTVN 1813
Query: 1629 KDGTKLETQHVVMPSQKSSLLTTLSNFWADRSASFWKPLTYPTSPTEHIFMDNNVIIRED 1688
K + P +KS L+ TLSNFWADRSA WKPL YPT P+EHIF D++VIIRED
Sbjct: 1814 K------VESTPQP-EKSLLMKTLSNFWADRSAYLWKPLVYPTCPSEHIFTDSDVIIRED 1866
Query: 1689 EPSSLIAFCLSSNDYQRKVTAMIRNVRQ-------------TPGSF--DSQNGKPDLN-- 1731
EPSSLIAFCLS++DY+ K+ M NV+Q T G+ +Q G P +N
Sbjct: 1867 EPSSLIAFCLSTSDYRNKM--MNLNVQQQQQQQTAEAAPAKTGGNSGGTTQTGDPSVNIS 1924
Query: 1732 -------------------------TLKTESME-----TKLDADSHEISCKASNTDLEMI 1761
L T +E T ++ +H + + +LE I
Sbjct: 1925 PSVSTTSHNKGRDSEISSLVTTKEGLLNTPPIEGARDRTPQESQTHSQANLDTLQELEKI 1984
Query: 1762 MTKKTGMHLRYQFQDGNTIMSCKIFFFEQFDAFRKKCGCGEENFIQSLSRCIKWDSSGGK 1821
MTKKT HLRYQF++G T+MSCKIFF E FD FRK C C +ENFIQSLSRC+KWDS+GGK
Sbjct: 1985 MTKKTATHLRYQFEEGLTVMSCKIFFTEHFDVFRKICDC-QENFIQSLSRCVKWDSNGGK 2043
Query: 1822 SGSAFLKTLDDRFVIKELSHSELDAFINFSSSYFEYMSQALFHDLPTALAKILGFYQIQI 1881
SGS FLKTLDDRF+IKELSH+EL+AFI F+ SYFEYM+QA+FHDLPT LAK+ GFYQIQ+
Sbjct: 2044 SGSGFLKTLDDRFIIKELSHAELEAFIKFAPSYFEYMAQAMFHDLPTTLAKVFGFYQIQV 2103
Query: 1882 RNA-ATGKSFKMDVIIMENLFYEKKTSRIFDLKGSMRNRHVEQTGKENEVLLDENMVEYI 1940
+++ ++ KS+KMDVIIMENLFYEKKT+RIFDLKGSMRNRHVEQTGK NEVLLDENMVEYI
Sbjct: 2104 KSSISSSKSYKMDVIIMENLFYEKKTTRIFDLKGSMRNRHVEQTGKANEVLLDENMVEYI 2163
Query: 1941 YESPIFVREYDKKLLRASLWNDTLFLAKMNVMDYSLVVGVDNQTHSLTVGIIDCIRTFTW 2000
YESPI VREYDKKLLRAS+WNDTLFLAKMNVMDYSLV+G+DN+ ++LTVGIID IRTFTW
Sbjct: 2164 YESPIHVREYDKKLLRASVWNDTLFLAKMNVMDYSLVIGIDNEGYTLTVGIIDFIRTFTW 2223
Query: 2001 DKKLESWVKEKGLVGGST--KEPTVVTPRQYKNRFREAMDRYILMVPDPWY 2049
DKKLESWVKEKGLVGG++ K+PTVVTPRQYK RFREAM+RYILMVPDPWY
Sbjct: 2224 DKKLESWVKEKGLVGGASVIKQPTVVTPRQYKKRFREAMERYILMVPDPWY 2274
>SPBC6B1.11c [T] KOG0230 Phosphatidylinositol-4-phosphate 5-kinase and related
FYVE finger-containing proteins
Length = 614
Score = 454 bits (1169), Expect = e-127
Identities = 265/612 (43%), Positives = 367/612 (59%), Gaps = 45/612 (7%)
Query: 1435 KSATTNTFSEETIGKVTGPRKQSMTSSLDRNLIRKNSNNSTYTQSSKDRNSDTKVGQLAN 1494
KSA+T+ +G ++SS+ I N++ Y+ D +V L
Sbjct: 37 KSASTSDRRFVNASSTSG-MNMPISSSISAK-ISSIQNSTKYSPRKPIPAKDVRVSSLVR 94
Query: 1495 FFDQIHFDSVTREFELQREMERLHMNKTKYQAMRAKSLKPLVEIYKNVQDAVEEPINVDK 1554
F+++ E Q+ E L + K +A+ KP+VE++ ++ +A ++ + D+
Sbjct: 95 RFEELSLQLQ----EKQKRDEELIKARRK-RALPVVPSKPVVEVFNDLNEAFDDENSEDE 149
Query: 1555 GAKNQNSLVNSDNTQGTYDTAKPLNKGLENELEQSINQWSERVLQNQTGDQPVDITAKPS 1614
N + T+ + ++K EN N S ++ G + +
Sbjct: 150 NGINDTK--ENRATESNFSGVDSMSKERENVSSNEDN--SPEAFEDIFGILFKNESGLEE 205
Query: 1615 NEPLPPVTTITNANKDGTKLETQHVVMPSQKSSLLTTLSNFWADRSASFWKPLTYPTSPT 1674
+ L P + + +K+G+KL T + + K+S+ LS FW + ++ P +P PT
Sbjct: 206 QQNLEPSSQM---DKEGSKLPTSGPL--ADKTSVYRILSAFWNEWNSLNPPPFEFPLQPT 260
Query: 1675 EHIFMDNNVIIREDEPSSLIAFCLSSNDYQRKVTAMIRNVRQTPGSFDSQNGKPDLNTLK 1734
EH+F D+NVIIREDEPSSLI+F LSS DY K+ +
Sbjct: 261 EHMFSDSNVIIREDEPSSLISFTLSSPDYLSKMVEI------------------------ 296
Query: 1735 TESMETKLDADSHEISCKASNTDLEMIMTKKTGMHLRYQFQDGNTIMSCKIFFFEQFDAF 1794
+SM+ L + S + +E +M K TG HL+YQF++G+ +SCK+FF EQF A
Sbjct: 297 EDSMDEALTNQGLQGSTQFK---IENLMLKPTGTHLKYQFEEGSARLSCKVFFAEQFSAL 353
Query: 1795 RKKCGCGEENFIQSLSRCIKWDSSGGKSGSAFLKTLDDRFVIKELSHSELDAFINFSSSY 1854
R+ CGC EE F+ SL+RC W+SSGGKSGSAFLKT D ++++K LS E D+ +NF+ +Y
Sbjct: 354 RRACGC-EETFVTSLARCSLWESSGGKSGSAFLKTFDKKYILKVLSRLESDSLLNFAPAY 412
Query: 1855 FEYMSQALFHDLPTALAKILGFYQIQIRNAATGKSFKMDVIIMENLFYEKKTSRIFDLKG 1914
F+Y+S+ FH+LPTAL KI GFY++ IRN TG K D++IMEN+FY++ SRIFDLKG
Sbjct: 413 FDYISKVFFHELPTALTKIFGFYRVDIRNPTTGTICKTDIMIMENVFYDECPSRIFDLKG 472
Query: 1915 SMRNRHVEQTGKENEVLLDENMVEYIYESPIFVREYDKKLLRASLWNDTLFLAKMNVMDY 1974
SMRNRHVE TGK +EVLLDEN+VE IYESPIFV E K LL + LWNDTLFL+K+N+MDY
Sbjct: 473 SMRNRHVESTGKVDEVLLDENLVELIYESPIFVSEQLKSLLHSCLWNDTLFLSKLNIMDY 532
Query: 1975 SLVVGVDNQTHSLTVGIIDCIRTFTWDKKLESWVKEKGLVGGSTKEPTVVTPRQYKNRFR 2034
SL+VG+D L VGIID IRT+TWDKKLESWVKEKGLVG EPT+VTP+QYKNRFR
Sbjct: 533 SLIVGIDYTKKELYVGIIDFIRTYTWDKKLESWVKEKGLVGRG-PEPTIVTPKQYKNRFR 591
Query: 2035 EAMDRYILMVPD 2046
+AMD YIL D
Sbjct: 592 KAMDCYILASQD 603
>At4g33240 [T] KOG0230 Phosphatidylinositol-4-phosphate 5-kinase and related
FYVE finger-containing proteins
Length = 1757
Score = 305 bits (781), Expect = 5e-82
Identities = 163/376 (43%), Positives = 239/376 (63%), Gaps = 19/376 (5%)
Query: 1685 IREDEPSSLIAFCLSSNDYQRKVTAM--IRNVRQTPGSF---DSQN--GKPDLNTLKTES 1737
+ +DEP+S+IA+ L+S++Y+ +++ R+ + GSF DS N L+ L +
Sbjct: 1358 VYDDEPTSIIAYALTSSEYKAQMSGSDKSRDRLDSGGSFSLFDSVNLLSLNSLSDLSVDM 1417
Query: 1738 METKLDADSHEISCKASNTDLEMIMTKKTGMHLRYQFQD----GNTIMSCKIFFFEQFDA 1793
+ AD S+ L+ +H R F D G S ++ ++F+A
Sbjct: 1418 SRSLSSADEQVSQLLHSSLYLK-------DLHARISFTDEGPPGKVKYSVTCYYAKEFEA 1470
Query: 1794 FRKKCGCGEENFIQSLSRCIKWDSSGGKSGSAFLKTLDDRFVIKELSHSELDAFINFSSS 1853
R C E +FI+SL RC KW + GGKS F K+LDDRF+IK+++ +EL++FI F +
Sbjct: 1471 LRMICCPSETDFIRSLGRCRKWGAQGGKSNVFFAKSLDDRFIIKQVTKTELESFIKFGPA 1530
Query: 1854 YFEYMSQALFHDLPTALAKILGFYQIQIRNAATGKSFKMDVIIMENLFYEKKTSRIFDLK 1913
YF+Y+++++ PT+LAKILG YQ+ ++ GK FKMDV++MENL +++ +R++DLK
Sbjct: 1531 YFKYLTESISTKSPTSLAKILGIYQVSSKHLKGGKEFKMDVLVMENLLFKRNFTRLYDLK 1590
Query: 1914 GSMRNRHVEQTGKENEVLLDENMVEYIYESPIFVREYDKKLLRASLWNDTLFLAKMNVMD 1973
GS R R+ T N VLLD+N+VE + SPIFV K+LL ++WNDT FLA ++VMD
Sbjct: 1591 GSTRARYNPDTSGSNTVLLDQNLVEAMPTSPIFVGSKAKRLLERAVWNDTSFLASIHVMD 1650
Query: 1974 YSLVVGVDNQTHSLTVGIIDCIRTFTWDKKLESWVKEKGLVGG-STKEPTVVTPRQYKNR 2032
YSL+VGVD + + L +GIID +R +TWDK LE+WVK GL+GG PTV++P+QYK R
Sbjct: 1651 YSLLVGVDEERNELVLGIIDFMRQYTWDKHLETWVKTSGLLGGPKNSTPTVISPQQYKKR 1710
Query: 2033 FREAMDRYILMVPDPW 2048
FR+AM Y LMVPD W
Sbjct: 1711 FRKAMTAYFLMVPDQW 1726
Score = 142 bits (359), Expect = 4e-33
Identities = 91/282 (32%), Positives = 153/282 (53%), Gaps = 17/282 (6%)
Query: 657 LNDVCKLHLEALLQQALTDQEIP--GEGD---WIAIFNKMIGQIQGI-PLDARKAGDLDF 710
+ +V + H AL+ Q L +P EGD W+ I + + + D K+G +D
Sbjct: 365 MKNVVEGHFRALVAQLLEVDNLPMVNEGDEEGWLDIITSLSWEAATLLKPDTSKSGGMD- 423
Query: 711 KQQHVKIKRLPGGSVLDSMILNGVLYSKGLPLKTMPRVVMNPRILLIMFPLEYQKHNNHV 770
+VK+K +P G +SM++ GV+ K + + M + PR+L++ LEYQ+ +N +
Sbjct: 424 PGGYVKVKCIPCGRRSESMVVKGVVCKKNVAHRRMTSKIEKPRLLILGGALEYQRISNQL 483
Query: 771 ISIESVVAQEKEYLKKLVLRLQSLNPDIILTGTSASGYALQLFQEVGIVVQCNVKPQVIE 830
S ++++ QE ++LK V ++ S NPDI+L S S +A + I + N+K ++E
Sbjct: 484 SSFDTLLQQEMDHLKMAVAKIDSHNPDILLVEKSVSRFAQEYLLAKDISLVLNIKRSLLE 543
Query: 831 RISRFTGCDIVITMDKLSSNIKLGTCERFEVRTYIYGNLS---------KNYTFITGCKT 881
RISR TG IV ++D+L+S KLG C+ F V ++ ++S K F GC
Sbjct: 544 RISRCTGAQIVPSIDQLTSP-KLGYCDLFHVEKFVETHVSPCQVAKKMAKTLMFFDGCPK 602
Query: 882 QAGITLVLRGNTSEVLRKVKDVAEFVAYAVFSMKLESSFFND 923
G T++L+G + L+KVK V ++ +A + + LE+SF D
Sbjct: 603 PLGCTILLKGAHEDELKKVKHVIQYGVFAAYHLALETSFLAD 644
Score = 81.3 bits (199), Expect = 2e-14
Identities = 66/294 (22%), Positives = 131/294 (44%), Gaps = 18/294 (6%)
Query: 1067 HQSISVLYSVISRKTTTPCIGPEIVTIDFFWENDISIGQFIENVVATAFRPCADGCGGLM 1126
HQSI V S + C ++ I ++ D +G+F+ + + + C C
Sbjct: 822 HQSILVSLSTRCVWKGSVCERAHLLRIKYYGSFDKPLGRFLRDNLFDQDQ-CCPSCTMPA 880
Query: 1127 IDHYRSYAHGNGKLDVIIERLQSKMP-MLKNLILTWSYCKKC----GLSSPT--LQLSEK 1179
H Y H G L + +++L +P + I W C KC G T + +S+
Sbjct: 881 EAHIHCYTHRQGSLTISVKKLPELLPGQREGKIWMWHRCLKCPRINGFPPATRRIVMSDA 940
Query: 1180 SWNYSLGKYLELMFWSSPKNINSIGNCTHDVAKDHLKYFSLNDLVVRMEYSGIDVHELIT 1239
+W S GK+LEL F S+ + + NC H + +D L+++ +V Y+ I+++ +
Sbjct: 941 AWGLSFGKFLELSF-SNHAAASRVANCGHSLHRDCLRFYGFGRMVACFRYASINIYAVTL 999
Query: 1240 PTATITWNPGKDIKLKVELYYQILEKIDAFYGSVLERLNKLKIDSI----NDLKLNEAKE 1295
P A + +N L+ E ++++K + + V E L+++ ++ N+ K
Sbjct: 1000 PPAKLYFNYENQEWLQKE-SKEVIKKAEVLFNEVQEALSQISAKTMGAGSKGSTPNKIKL 1058
Query: 1296 RIVQLKVLVEDEKSTLGANMETIYTGLEGDQH----LQLNSIVRALHDNAAGWD 1345
+ +L L+E K +++ + ++ Q L +N + R + ++ WD
Sbjct: 1059 SLEELAGLLEQRKKEYKDSLQQMLNVVKDGQPTIDILLINKLRRLIIFDSYAWD 1112
Score = 72.4 bits (176), Expect = 7e-12
Identities = 45/168 (26%), Positives = 74/168 (43%), Gaps = 20/168 (11%)
Query: 244 LSKEYWMKDESAKECFNCAKPFTTFRRKHHCRICGQIFCSSCSFLI-------TGESFGY 296
+S+++WM D+S C+ C FT F R+HHCR+CG++FC+ C+ T +S
Sbjct: 28 MSRDFWMPDQSCPVCYECDAQFTVFNRRHHCRLCGRVFCAKCAANSIPSPSDETKDSHEE 87
Query: 297 SGRMRICGKCYEHSMNYXXXXXXXXXXXIIH--DQVSSRNIDDDAPSLNNDDIQSILTNV 354
R+R+C CY+ +H S+R++ + +N I S
Sbjct: 88 PERIRVCNYCYKQWEQGIVPPDNGASIISLHFSSSPSARSVASTTSNSSNCTIDS----- 142
Query: 355 DDHKVHISTPEPLPRMAIPATKQGESLEISFHSKANNHGYRKSRPRRG 402
+ P P P+M A+++ S S S+ N R+S G
Sbjct: 143 ------TAGPSPRPKMNPRASRRVSSNMDSEKSEQQNAKSRRSSDHYG 184
>At3g14270 [T] KOG0230 Phosphatidylinositol-4-phosphate 5-kinase and related
FYVE finger-containing proteins
Length = 1791
Score = 305 bits (781), Expect = 5e-82
Identities = 163/372 (43%), Positives = 238/372 (63%), Gaps = 9/372 (2%)
Query: 1683 VIIREDEPSSLIAFCLSSNDYQRKVTAMIRNVRQTPGSFDSQNGKPDLNTLKTESMET-K 1741
V + +DEP+S+IA+ L S +YQR+ +A ++ P + +P +T+ S
Sbjct: 1397 VPVYDDEPTSMIAYALMSPEYQRQTSAEGESLVSYPSELNIP--RPVDDTIFDPSRSNGS 1454
Query: 1742 LDADSHEISCKASNTDLEMIMTKKTGMHLRYQFQDGNTIMSCKI----FFFEQFDAFRKK 1797
+D IS S + L+ + K +H R + + T+ K ++ ++F+A R
Sbjct: 1455 VDESILSISSSRSTSLLDPLSYTKA-LHARVSYGEDGTLGKVKYTVTCYYAKRFEALRGI 1513
Query: 1798 CGCGEENFIQSLSRCIKWDSSGGKSGSAFLKTLDDRFVIKELSHSELDAFINFSSSYFEY 1857
C E +I+SLSRC KW + GGKS F KTLDDRF+IK+++ +EL++FI F+ +YF+Y
Sbjct: 1514 CLPSELEYIRSLSRCKKWGAQGGKSNVFFAKTLDDRFIIKQVTKTELESFIKFAPAYFKY 1573
Query: 1858 MSQALFHDLPTALAKILGFYQIQIRNAATGKSFKMDVIIMENLFYEKKTSRIFDLKGSMR 1917
+S+++ PT LAKILG YQ+ + +GK KMDV+IMENL + + R++DLKGS R
Sbjct: 1574 LSESISTKSPTCLAKILGIYQVATKQLKSGKETKMDVLIMENLLFGRTVKRLYDLKGSSR 1633
Query: 1918 NRHVEQTGKENEVLLDENMVEYIYESPIFVREYDKKLLRASLWNDTLFLAKMNVMDYSLV 1977
R+ + N+VLLD+N++E + SPIFV K+LL ++WNDT FLA +VMDYSL+
Sbjct: 1634 ARYNPDSSGSNKVLLDQNLIEAMPTSPIFVGNKAKRLLERAVWNDTAFLALGDVMDYSLL 1693
Query: 1978 VGVDNQTHSLTVGIIDCIRTFTWDKKLESWVKEKGLVGGSTKE-PTVVTPRQYKNRFREA 2036
VGVD + + L +GIID +R +TWDK LESWVK G++GG E PTV++P+QYK RFR+A
Sbjct: 1694 VGVDEEKNELVLGIIDFLRQYTWDKHLESWVKFTGILGGPKNEAPTVISPKQYKRRFRKA 1753
Query: 2037 MDRYILMVPDPW 2048
M Y LMVPD W
Sbjct: 1754 MTTYFLMVPDQW 1765
Score = 132 bits (333), Expect = 4e-30
Identities = 87/291 (29%), Positives = 150/291 (50%), Gaps = 17/291 (5%)
Query: 648 RISLDKREELNDVCKLHLEALLQQALTDQEIP-----GEGDWIAIFNKMIGQIQGI-PLD 701
R + + ++ + +V H ALL Q L + I G+ W+ I + + + D
Sbjct: 368 RTTEEHKKAMKNVVDGHFRALLAQLLQVENISVSDEEGKESWLEIITSLSWEAANLLKPD 427
Query: 702 ARKAGDLDFKQQHVKIKRLPGGSVLDSMILNGVLYSKGLPLKTMPRVVMNPRILLIMFPL 761
K+G +D +VK+K L G DSM++ GV+ K + + M + R+L++ L
Sbjct: 428 MSKSGGMD-PGGYVKVKCLASGFRHDSMVVKGVVCKKNVVNRRMSTKIEKARLLILGGGL 486
Query: 762 EYQKHNNHVISIESVVAQEKEYLKKLVLRLQSLNPDIILTGTSASGYALQLFQEVGIVVQ 821
EYQ+ +N + S ++++ QEK++LK V ++ + P+I+L S S +A + I +
Sbjct: 487 EYQRVSNQLSSFDTLLQQEKDHLKMAVAKIHAERPNILLVEKSVSRFAQEYLLAKDISLV 546
Query: 822 CNVKPQVIERISRFTGCDIVITMDKLSSNIKLGTCERFEVRTY---------IYGNLSKN 872
N+K +++RI+R TG I+ ++D LSS KLG CE F V Y + + K
Sbjct: 547 LNIKRPLLDRIARCTGAQIIPSVDHLSSQ-KLGYCENFRVDRYPEEHGSTGQVGKKVVKT 605
Query: 873 YTFITGCKTQAGITLVLRGNTSEVLRKVKDVAEFVAYAVFSMKLESSFFND 923
+ C G T++LRG + L+KVK V ++ +A + + LE+SF D
Sbjct: 606 LMYFEHCPKPLGFTILLRGANEDELKKVKHVVQYGVFAAYHLALETSFLAD 656
Score = 83.2 bits (204), Expect = 4e-15
Identities = 72/296 (24%), Positives = 132/296 (44%), Gaps = 24/296 (8%)
Query: 1067 HQSISVLYSVISRKTTTPCIGPEIVTIDFFWENDISIGQFIENVVATAFRPCADGCGGLM 1126
HQSI V S S T C + I ++ D +G+F+ + + C C
Sbjct: 857 HQSILVSLSSRSVWKGTVCERSHLFRIKYYGSFDKPLGRFLRDHLFDQSYRCRS-CEMPS 915
Query: 1127 IDHYRSYAHGNGKLDVIIERLQSKM--PMLKNLILTWSYCKKC----GLSSPTLQ--LSE 1178
H Y H G L + +++LQ + + I W C +C G TL+ +S+
Sbjct: 916 EAHVHCYTHRQGSLTISVKKLQDYLLPGEKEGKIWMWHRCLRCPRLNGFPPATLRVVMSD 975
Query: 1179 KSWNYSLGKYLELMFWSSPKNINSIGNCTHDVAKDHLKYFSLNDLVVRMEYSGIDVHELI 1238
+W S GK+LEL F S+ + + C H + +D L+++ ++V Y+ IDVH +
Sbjct: 976 AAWGLSFGKFLELSF-SNHAAASRVACCGHSLHRDCLRFYGFGNMVACFRYATIDVHSVY 1034
Query: 1239 TPTATITWNPGKDIKLKVELYYQILEKIDAFYGSVLERLNKLKIDSINDLKLNEAKERIV 1298
P + +++N ++ E +++E+ + + VL ++I+ + + RI
Sbjct: 1035 LPPSILSFNYENQDWIQRET-DEVIERAELLFSEVL--------NAISQIAEKGFRRRIG 1085
Query: 1299 QLKVLVEDEKSTLGANMETIY-----TGLEGDQHLQLNSIVRALHDNAAGWDNEFV 1349
+L+ +++ EK+ NM+ I G L+L I R L + WD+ +
Sbjct: 1086 ELEEVLQKEKAEFEENMQKILHREVNEGQPLVDILELYRIHRQLLFQSYMWDHRLI 1141
Score = 60.8 bits (146), Expect = 2e-08
Identities = 25/75 (33%), Positives = 40/75 (53%), Gaps = 15/75 (20%)
Query: 244 LSKEYWMKDESAKECFNCAKPFTTFRRKHHCRICGQIFCSSCSFLITGESFGYS------ 297
+S+++WM D+S + C+ C FT R+HHCR CG++FC C T S ++
Sbjct: 31 VSRDFWMPDQSCRVCYECDCQFTLINRRHHCRHCGRVFCGKC----TANSIPFAPSDLRT 86
Query: 298 -----GRMRICGKCY 307
R+R+C C+
Sbjct: 87 PREDWERIRVCNYCF 101
>At1g71010 [T] KOG0230 Phosphatidylinositol-4-phosphate 5-kinase and related
FYVE finger-containing proteins
Length = 1609
Score = 293 bits (751), Expect = 2e-78
Identities = 152/378 (40%), Positives = 232/378 (61%), Gaps = 22/378 (5%)
Query: 1683 VIIREDEPSSLIAFCLSSNDYQRKVTAMIRNVRQTPGSFDSQNGKPD-LNTLKTESMETK 1741
V + +D+P+S++++ ++S +Y+ + + + +++ +P +T ++ SM
Sbjct: 1240 VPVYDDDPASVVSYAINSKEYKEWIVNKGLASSSSSSNLNNRESEPSAFSTWRSLSM--- 1296
Query: 1742 LDADSHEISCKASNTDLEMIMTKKTGMHLRYQFQD----------GNTIMSCKIFFFEQF 1791
D D + + S+ D + HL F D G S +F QF
Sbjct: 1297 -DVDYIQHAVYGSSQD------DRKSPHLTISFSDRASSSSTATEGKVKFSVTCYFATQF 1349
Query: 1792 DAFRKKCGCGEENFIQSLSRCIKWDSSGGKSGSAFLKTLDDRFVIKELSHSELDAFINFS 1851
D RK C E +F++SLSRC +W + GGKS F K+LD+RF+IK++ +ELD+F +F+
Sbjct: 1350 DTLRKTCCPSEVDFVRSLSRCQRWSAQGGKSNVYFAKSLDERFIIKQVVKTELDSFEDFA 1409
Query: 1852 SSYFEYMSQALFHDLPTALAKILGFYQIQIRNAATGKSFKMDVIIMENLFYEKKTSRIFD 1911
YF+Y+ ++L PT LAKILG YQ+ I++ GK KMD+++MENLFY ++ SRI+D
Sbjct: 1410 PEYFKYLKESLSSGSPTCLAKILGIYQVSIKHPKGGKETKMDLMVMENLFYNRRISRIYD 1469
Query: 1912 LKGSMRNRHVEQTGKENEVLLDENMVEYIYESPIFVREYDKKLLRASLWNDTLFLAKMNV 1971
LKGS R+R+ T ++VLLD N++E + PIF+ K+ L ++WNDT FLA ++V
Sbjct: 1470 LKGSARSRYNPNTSGADKVLLDMNLLETLRTEPIFLGSKAKRSLERAIWNDTNFLASVDV 1529
Query: 1972 MDYSLVVGVDNQTHSLTVGIIDCIRTFTWDKKLESWVKEKGLVGG-STKEPTVVTPRQYK 2030
MDYSL+VG D + L +GIID +R +TWDK LE+WVK G++GG PT+V+P+QYK
Sbjct: 1530 MDYSLLVGFDEERKELVLGIIDFMRQYTWDKHLETWVKASGILGGPKNASPTIVSPKQYK 1589
Query: 2031 NRFREAMDRYILMVPDPW 2048
RFR+AM Y L VP+PW
Sbjct: 1590 RRFRKAMTTYFLTVPEPW 1607
Score = 210 bits (534), Expect = 2e-53
Identities = 218/904 (24%), Positives = 386/904 (42%), Gaps = 121/904 (13%)
Query: 645 TWRRISLDKREELNDVCKLHLEALLQQALTDQEIP-----GEGDWIAIFNKMIGQIQG-I 698
T ++ + E L V H AL+ + L +E+ G+W+ I + Q +
Sbjct: 270 TKEKLGENSNEPLRTVVHDHFRALVAELLRGEELSPSDDGSAGEWLDIVTALAWQAANFV 329
Query: 699 PLDARKAGDLDFKQQHVKIKRLPGGSVLDSMILNGVLYSKGLPLKTMPRVVMNPRILLIM 758
D R G +D +VKIK + G+ +S+++ G++ SK + K M NPR++L+
Sbjct: 330 KPDTRAGGSMD-PGNYVKIKCVASGNQNESILIRGIVCSKNITHKRMISQYKNPRVMLLA 388
Query: 759 FPLEYQKHNNHVISIESVVAQEKEYLKKLVLRLQSLNPDIILTGTSASGYALQLFQEVGI 818
LEYQ+ + S +++ QE E++K ++ +++SL P+++L SAS YA Q E I
Sbjct: 389 GSLEYQRVAGQLASFNTLLQQENEHMKAIIAKIESLRPNVLLVEKSASSYAQQYLLEKEI 448
Query: 819 VVQCNVKPQVIERISRFTGCDIVITMDKLSSNIKLGTCERFEVRTYI----YGNL----- 869
+ NVK +++RI+R TG + ++D +S+ +LG CE F + GN
Sbjct: 449 SLVLNVKRSLLDRIARCTGAVLCPSLDSIST-ARLGHCELFRTERVLEQHEAGNQSNRKP 507
Query: 870 SKNYTFITGCKTQAGITLVLRGNTSEVLRKVKDVAEFVAYAVFSMKLESSFFNDNFLQLN 929
S+ + GC + G T+VLRG+ E L+KVK V ++ +A + + LE+SF D L
Sbjct: 508 SRTLMYFEGCPRRLGCTVVLRGSCREELKKVKHVIQYAVFAAYHLSLETSFLADEGASLP 567
Query: 930 IEAYKHIQLLKKQNESFTGFFADFIEKFNRRIL--SVSPIVEFPVPYLLQKARDVEQQLI 987
K +++ ++ RRI+ +S I + P Q +
Sbjct: 568 KIRLKQPGMVRTASQ--------------RRIIDEGISLITQSPTETDSQALLETAAHED 613
Query: 988 EKTALVKKLQDCAEILEYKDSIDLSKMQLETALTQRDF------------KYLIGFINNK 1035
E TA + + + C + E D + E Q D Y +N+
Sbjct: 614 EHTAPMPEHEVCESLCEDFDPTQIFPPSSEVETEQSDTLNGDFANNLVTRSYSSNQLNDL 673
Query: 1036 ECDALKLQFETLKKKWEIYSSLSHNMLG------------------------------TG 1065
L L E + + S N G
Sbjct: 674 HEPTLCLSSEIPETPTQQPSGEEDNGRGEEENQLVNPQDLPQHESFYEDDVSSEYFSAAD 733
Query: 1066 PHQSISVLYSVISRKTTTPCIGPEIVTIDFFWENDISIGQFIENVVATAFRPCADGCGGL 1125
HQSI V +S + C ++ I F+ D +G+++++ + C C L
Sbjct: 734 SHQSILVSFSSRCVLKESVCERSRLLRIKFYGSFDKPLGRYLKDDLFDKTSSCR-SCKEL 792
Query: 1126 MIDHYRSYAHGNGKLDVIIERLQS-KMPMLKN-LILTWSYCKKC----GLSSPT--LQLS 1177
+ H Y+H NG L + + RL S K+P ++ I W C +C G+ T + +S
Sbjct: 793 VDAHVLCYSHQNGNLTINVRRLPSMKLPGEQDGKIWMWHRCLRCAHVDGVPPATRRVVMS 852
Query: 1178 EKSWNYSLGKYLELMFWSSPKNINSIGNCTHDVAKDHLKYFSLNDLVVRMEYSGIDVHEL 1237
+ +W S GK+LEL F S+ N + +C H + +D L+++ ++V YS I++ +
Sbjct: 853 DAAWGLSFGKFLELSF-SNHATANRVASCGHSLQRDCLRFYGFGNMVAFFRYSPINILTV 911
Query: 1238 ITPTATITWNPGKDIKLKVELYYQILEKIDAFYGSVLERLNKL-KIDSINDLKLNEA--- 1293
+ P + + +N + +++ K+ Y + + LN++ + S+ + + +EA
Sbjct: 912 LLPPSMLEFNSHPQQEWIRTEAAELVGKMRTMYTEISDMLNRMEEKSSLLEPEQSEACDL 971
Query: 1294 KERIVQLKVLVEDEKSTLGANMETIY---TGLEGD-QHLQLNSIVRALHDNAAGWDNEFV 1349
RI+ L + EK ++ I+ ++G L+LN + RAL A WD++
Sbjct: 972 HSRIIGLIDQLVKEKDEYDDALQPIFEENLQIQGSLDILELNRLRRALMIGAHAWDHQLY 1031
Query: 1350 EFEKEFLPTEKDIARITALQLKKMFTDFNKMTEDNGIKEINGEDAEAEEK--SKCMDTTS 1407
+ QLKK K +DN + D ++ + D
Sbjct: 1032 ---------------LLNSQLKK--ASVFKTGDDNAPRNPEMHDPPKIDRRMQEGSDERD 1074
Query: 1408 EEQRSDEESDASPPKPKSVQNAELPL---IKSATTNTFSE----ETIGKVTGPRKQSMTS 1460
E+ +D E++ P+++ + L I SA +F ETI + G ++ S
Sbjct: 1075 EQSHTDSEANGDNKDPENIPSPGTSLSERIDSAWLGSFQNLEKAETIAETEG--FSAVNS 1132
Query: 1461 SLDR 1464
SL R
Sbjct: 1133 SLRR 1136
>Hs14729948 [T] KOG0230 Phosphatidylinositol-4-phosphate 5-kinase and related
FYVE finger-containing proteins
Length = 558
Score = 286 bits (733), Expect = 2e-76
Identities = 170/475 (35%), Positives = 257/475 (53%), Gaps = 73/475 (15%)
Query: 1644 QKSSLLTTLSNFWADRSASFWKPLTYPTSPTEHIFMDNN----VIIREDEPSSLIAFCLS 1699
+KS++ +N S + P+ +P P +H M + + + E EPSS+IAF LS
Sbjct: 80 EKSTMKAIFANLLPGNS---YNPIPFPFDPDKHYLMYEHERVPIAVCEKEPSSIIAFALS 136
Query: 1700 SNDYQRKV--------------------TAMIRNVRQTPGSFDSQNGKPDLNTLKTESME 1739
+Y+ + T+ R +P +G T +TE
Sbjct: 137 CKEYRNALEELSKATQWNSAEEGLPTNSTSDSRPKSSSPIRLPEMSGGQTNRTTETEPQP 196
Query: 1740 TK------------------LDADSHEISCKASNTDLEMIMTKKTGM------------- 1768
TK L + E A + ++ T K G
Sbjct: 197 TKKASGMLSFFRGTAGKSPDLSSQKRETLRGADSAYYQVGQTGKEGTENQGVEPQDEVDG 256
Query: 1769 -----------HLRYQFQDGNTIMSCKIFFFEQFDAFRKKC-GCGEENFIQSLSRCIKWD 1816
H+ QF D N C++++ +F R+ EE+FI+SLS W
Sbjct: 257 GDTQKKQLINPHVELQFSDANAKFYCRLYYAGEFHKMREVILDSSEEDFIRSLSHSSPWQ 316
Query: 1817 SSGGKSGSAFLKTLDDRFVIKELSHSELDAFINFSSSYFEYMSQALFHDLPTALAKILGF 1876
+ GGKSG+AF T DDRF++K++ E+ +F++F+ YF Y++ A+ PTALAKILG
Sbjct: 317 ARGGKSGAAFYATEDDRFILKQMPRLEVQSFLDFAPHYFNYITNAVQQKRPTALAKILGV 376
Query: 1877 YQIQIRNAATGKSFKMDVIIMENLFYEKKTSRIFDLKGSMRNRHVE-QTGKEN--EVLLD 1933
Y+I +N+ K+D+++MENLFY +K +++FDLKGS+RNR+V+ TGKE+ VLLD
Sbjct: 377 YRIGYKNSQNNTEKKLDLLVMENLFYGRKMAQVFDLKGSLRNRNVKTDTGKESCDVVLLD 436
Query: 1934 ENMVEYIYESPIFVREYDKKLLRASLWNDTLFLAKMNVMDYSLVVGVDNQTHSLTVGIID 1993
EN+++ + ++P+++R + K +LR S+ +D+ FL+ ++DYSL+VG D+ ++ L VGIID
Sbjct: 437 ENLLKMVRDNPLYIRSHSKAVLRTSIHSDSHFLSSHLIIDYSLLVGRDDTSNELVVGIID 496
Query: 1994 CIRTFTWDKKLESWVKEKGLVGGSTKEPTVVTPRQYKNRFREAMDRYILMVPDPW 2048
IRTFTWDKKLE VK G++GG K PTVV+P Y+ RF EAMD+Y LMVPD W
Sbjct: 497 YIRTFTWDKKLEMVVKSTGILGGQGKMPTVVSPELYRTRFCEAMDKYFLMVPDHW 551
>At1g34260 [T] KOG0230 Phosphatidylinositol-4-phosphate 5-kinase and related
FYVE finger-containing proteins
Length = 1456
Score = 251 bits (640), Expect = 1e-65
Identities = 175/535 (32%), Positives = 282/535 (52%), Gaps = 46/535 (8%)
Query: 1534 PLVEIYKNVQDAVEEPINVDKGAKNQNSLVNSDNTQGTY-----DTAKPLNKGLENELEQ 1588
PLVE +K++ A + D+ A+ S V DN T DT P+N + L
Sbjct: 942 PLVE-HKDIPIAGASVGDNDQMAE---SYVPEDNESQTLCSSSPDTTSPINNHFDTHLAV 997
Query: 1589 SINQWSERVLQNQTGDQPVDITAKPSNEPLPPVTTITNANKDG---------TKLETQHV 1639
+++ + Q D+ + +T + ++ V+T + G +L ++ +
Sbjct: 998 NVHSTN-----GQEADKSIPVTGESLDDE---VSTSNGPHILGWDEWFWLPFEELRSKRI 1049
Query: 1640 VMPSQKSSLLTT--LSNFWADRSASFWKPLTYPTSPTEHIFMDNNVIIR--EDEPSSLIA 1695
V +K LL ++NF + + + +T +S D++ I+ EDE SSLIA
Sbjct: 1050 V-DIEKEYLLKFEYVNNFTQENLQTVNQIITEESSRLRISLRDDDFIVSDYEDELSSLIA 1108
Query: 1696 FCLSSNDYQRKVTAMIRNVRQTPGSFDSQNGKPDLNTLKTESMETKLDADSHEISCKASN 1755
L+ + + + R + + F N +S +T D D S +++N
Sbjct: 1109 CALAHLNNEESKKPLSRCIHGSLQGFLDNN---------QDSKQT--DRDVSRFSSESTN 1157
Query: 1756 TDLEMIMTKKTGMHLRYQFQDGNTIMSCKIFFFEQFDAFRKKCGCGEENFIQSLSRCIKW 1815
LE + + + G S + + F RK+C E ++I SLSRC W
Sbjct: 1158 R-LETLPPPEVLVTFGSVKSVGKPKYSIVSLYADDFRDLRKRCCSSELDYIASLSRCKPW 1216
Query: 1816 DSSGGKSGSAFLKTLDDRFVIKELSHSELDAFINFSSSYFEYMSQALFHDLPTALAKILG 1875
D+ GGKS S F KTLDDRF++KE+ +E ++F+ F++ YF+YM + T LAK+LG
Sbjct: 1217 DAKGGKSKSVFAKTLDDRFIVKEIKKTEYESFVTFATEYFKYMKDSYDLGNQTCLAKVLG 1276
Query: 1876 FYQIQIRNA-ATGKSFKMDVIIMENLFYEKKTSRIFDLKGSMRNRHVEQTGK-ENEVLLD 1933
+Q+ +R GK + D+++MENL + +K +R +DLKG++ R + E++VLLD
Sbjct: 1277 IHQVTVRQPKGGGKEIRHDLMVMENLSFSRKVTRQYDLKGALHARFTATSANGEDDVLLD 1336
Query: 1934 ENMVEYIYESPIFVREYDKKLLRASLWNDTLFLAKMNVMDYSLVVGVDNQTHSLTVGIID 1993
+N V + +SP++V + K+ L+ +++NDT FL +NVMDYSL+VGVD++ H L GIID
Sbjct: 1337 QNFVNDMNKSPLYVSKTSKQNLQRAVYNDTSFLTSINVMDYSLLVGVDDENHELVCGIID 1396
Query: 1994 CIRTFTWDKKLESWVKEKGLVGGSTKEPTVVTPRQYKNRFREAMDRYILMVPDPW 2048
+R +TWDK+LE+WVK LV +PTV++P YK RFR+ M + L VPD W
Sbjct: 1397 YLRQYTWDKQLETWVK-SSLVVPKNVQPTVISPIDYKTRFRKFMKTHFLCVPDQW 1450
Score = 95.5 bits (236), Expect = 8e-19
Identities = 87/344 (25%), Positives = 155/344 (44%), Gaps = 37/344 (10%)
Query: 611 NNDLVFSKNQNPQLQKQKYDSNSKDARKSILNSSTWRRISL-----DKREELNDVCKLHL 665
++D+ + P+ + + D D + S W + SL D+ E V + +
Sbjct: 90 SDDVPVWEPPEPENPEDEVDGVFADDDDDCCDGSKWNKASLLGELSDESSEKRKVYEENR 149
Query: 666 EALLQQA------LTDQ-------EIPGEGDWIAIFNKMIGQIQGIPLDARKAGDLDFKQ 712
+L++A + Q I G W I ++ + + A +D
Sbjct: 150 RVMLEEADSKFKFIVSQLIKSAGFSIEESGYWFEIVARLCWEAASMLKPAIDGKSVD-PT 208
Query: 713 QHVKIKRLPGGSVLDSMILNGVLYSKGLPLKTMPRVVMNPRILLIMFPLEYQKHNNHVIS 772
+++K+K + GS +DS + G+++ K LK M +PRI+L+ L H S
Sbjct: 209 EYIKVKCIATGSCVDSEVFKGLVFKKHAALKHMATKYEHPRIMLVEGVLG---HPISGFS 265
Query: 773 IESVVAQEKEYLKKLVLR----LQSLNPDIILTGTSASGYALQLFQEVGIVVQCNVKPQV 828
V Q+ EYL K V +++ PD++L S S + + G+ + ++K
Sbjct: 266 SLQSVNQDNEYLLKYVKPVVDIIEASKPDVMLVEKSVSRDIQKTILDKGVTLVFDMKLHR 325
Query: 829 IERISRFTGCDIVITMDKLSSNIKLGTCERFEVRTYIYGNLS---------KNYTFITGC 879
++RISR G I +++D LSS KL C+ F + + + + K F+ GC
Sbjct: 326 LQRISRCIGSPI-LSVDSLSSQ-KLKHCDSFRIEKIVEEHNAAGESDKKPTKTLMFLEGC 383
Query: 880 KTQAGITLVLRGNTSEVLRKVKDVAEFVAYAVFSMKLESSFFND 923
T+ G T++L+G SE L+KVK+V ++ + + LE+SF D
Sbjct: 384 PTRLGCTILLKGCHSERLKKVKEVVQYSFILAYHLMLEASFLAD 427
Score = 60.5 bits (145), Expect = 3e-08
Identities = 63/279 (22%), Positives = 114/279 (40%), Gaps = 21/279 (7%)
Query: 1055 SSLSHNMLGTGPHQSISVLYSVISRKTTTPCIGPEIVTIDFFWENDISIGQFIENVVATA 1114
S +++ T QSI VL S + C I F+ D+ + +F+ ++
Sbjct: 585 SQTENDIESTLESQSILVLVSKRNALRGIMCDQRHFSHIKFYKHFDVPLEKFLRDMFNQ- 643
Query: 1115 FRPCADGCGGLMIDHYRSYAHGNGKLDVIIERLQSKMPML---KNLILTWSYCKKCGL-- 1169
R C H YAH N +L + I+R+ + K I WS C KC
Sbjct: 644 -RNLCQTCVEFPEAHLYYYAHQNKQLTIQIKRIPVAKGLAGEAKGKIWMWSRCGKCKTKN 702
Query: 1170 ----SSPTLQLSEKSWNYSLGKYLELMFWSSPKNINSIGNCTHDVAKDHLKYFSLNDLVV 1225
S+ + +S + + S GK+LEL F S +N +C H D L +F L +V
Sbjct: 703 ASRKSTKRVLISTAARSLSFGKFLELSF-SQQTFLNRSSSCGHSFDSDFLHFFGLGSMVA 761
Query: 1226 RMEYSGIDVHELITPTATITWNPGKDIKLKV----ELYYQILEKIDAFYGSVLERLNKLK 1281
+ YS + + + P + I +K + + + K + + L +L+
Sbjct: 762 MLSYSQVASYTVSLPPMKLE----SSILIKAGWLEKEFQTVFTKGISLFEDAAGFLKRLR 817
Query: 1282 IDSIN-DLKLNEAKERIVQLKVLVEDEKSTLGANMETIY 1319
N DL+ A++ + ++ L++ E+ N++ +
Sbjct: 818 SQFTNSDLRYQRARKLLSNIEELLKHERCIFEENIKNSF 856
>CE18979 [T] KOG0230 Phosphatidylinositol-4-phosphate 5-kinase and related
FYVE finger-containing proteins
Length = 1375
Score = 229 bits (585), Expect = 3e-59
Identities = 129/357 (36%), Positives = 211/357 (58%), Gaps = 22/357 (6%)
Query: 1704 QRKVTAMIRNVRQTPGSFDSQNGKPDLNTLKTESMET----KLDADSHEISCKASNTDLE 1759
Q ++ ++R+++ T G+F KPD+ ++ ++ K+ + +S ++++ L+
Sbjct: 1020 QPRLGVVVRDIQDTRGNF-----KPDIGSIIAYALSAVDYNKIPEAADTVSMDSASSSLK 1074
Query: 1760 MIMTKK-----TGMHLRYQFQDGNTIMSCKIFFFEQFDAFRKKCGC-GEENFIQSLSRCI 1813
+ HL +F+D + K+ + E+F R+ GEE FI+SLS
Sbjct: 1075 FSQMDDGENLASSQHLEVEFEDESASYYVKMLYAEKFRKLRELLIAEGEETFIRSLSNST 1134
Query: 1814 KWDSSGGKSGSAFLKTLDDRFVIKELSHSELDAFINFSSSYFEYMSQALFHDLPTALAKI 1873
W GGKSGS F +T DDRFV+K++S E+ +F+ F+ +YF+Y++ + T L K+
Sbjct: 1135 FWTPQGGKSGSFFYRTQDDRFVVKQMSRFEIQSFVKFAPNYFDYLTTSATESKLTTLCKV 1194
Query: 1874 LGFYQIQIRNAATGKSFKMDVIIMENLFYEKKTSRIFDLKGSMRNRHVEQTGKE-NE-VL 1931
G ++I ++ T + K+D+++ME LFY S+++DLKGS+RNR + TGK NE VL
Sbjct: 1195 YGVFRIGYKSKTT--TLKVDILVMEYLFYNHNVSQVWDLKGSLRNR-LASTGKSANEMVL 1251
Query: 1932 LDENMVEYIYESPIFVREYDKKLLRASLWNDTLFLAKMNVMDYSLVVGVDNQTHSLTVGI 1991
LDEN V+ ++ ++V + K + ++ ND+ FL+ +MDYSL+VGVD+ L +GI
Sbjct: 1252 LDENFVKDLWNQQLYVLPHSKAAMNQAISNDSHFLSSQYIMDYSLLVGVDDDNGELILGI 1311
Query: 1992 IDCIRTFTWDKKLESWVKEKGLVGGSTKEPTVVTPRQYKNRFREAMDRYILMVPDPW 2048
+D +RT+T DKKLESWVK + G PT+++P Y RF EA+D Y +VPD W
Sbjct: 1312 VDYMRTYTLDKKLESWVKIVAIPGAHL--PTILSPEMYCARFSEAIDSYFPVVPDQW 1366
Score = 165 bits (418), Expect = 6e-40
Identities = 153/625 (24%), Positives = 289/625 (45%), Gaps = 31/625 (4%)
Query: 641 LNSSTWRRISLDKREELNDVCKLHLEALLQQALTDQEIPGEGDWIAIFNKMIGQI-QGIP 699
L+ S ++R+ L ++ + + E +L + + + I E W + K + ++ + +
Sbjct: 246 LDESVMNAAKEEQRDNLEELFRRNTERILDEVMKREYIR-EDKWRDLILKSVYEVVENVT 304
Query: 700 LDARKAGDLDFKQQ-HVKIKRLPGGSVLDSMILNGVLYSKGLPLKTMPRVVMNPR----I 754
++ ++ HVK G V DS I+ GV S+ L K++ + I
Sbjct: 305 VNVPSGDTMNIADYVHVKKVHKKEGKV-DSEIIWGVACSRSLVYKSLSEEDESSHTTESI 363
Query: 755 LLIMFPLEYQKHNNHVISIESVVAQEKEYLKKLVLRLQSLNPDIILTGTSASGYALQLFQ 814
+++ +EY++ +N + SIE ++ QE+++L+K + R+ + +IL S A QL
Sbjct: 364 MIVSGSIEYERVSNKLSSIEPIIVQEEKFLEKQIDRIATKRASLILVEGGVSHIAAQLLH 423
Query: 815 EVGIVVQCNVKPQVIERISRFTGCDIVITMDKLSSNIKLGTCERFEVRTYIY-GNLSKNY 873
+ GI V NVK +++RISR TG DIV D LG C F+ R K
Sbjct: 424 KRGIKVAVNVKMSILQRISRATGADIVSNSDSQLVEQNLGCCPEFQQRNMQQEDGRIKTL 483
Query: 874 TFITGCKTQAGITLVLRGNTSEVLRKVKDVAEFVAYAVFSMKLESSFFNDNFLQLNIEAY 933
C+ + G T++L G+ + L VK V +F+ V+S LE S+ N +
Sbjct: 484 MIFADCQKETGCTVLLHGDDLKELVAVKRVVQFLVTIVYSNYLEQSYLNAFNTTIARRQS 543
Query: 934 KHIQLLKKQNESFT-GFFADFIEKFNRRILSVSPIVEFPVPYLLQKARDVEQQLIE--KT 990
+ K++ ++ G +F + +LS SP++EF P LL+ A E LI K
Sbjct: 544 DCVVCEKRRAIVYSQGEKTEFEKNLYATMLSSSPVIEFEPP-LLETATGRECPLIAYFKQ 602
Query: 991 ALVKKLQ-DCAEILEY---KDSIDLSKMQLETALTQRDFKYLIGFINNKECDALKLQFET 1046
L K L+ E+++ +D + + K + + F IN + A ++
Sbjct: 603 PLYKLLKPGDVELIKQGYEEDIVPIPKKEPLLVDRRHAFAQCNRGINFRRRTAQIVKHRK 662
Query: 1047 LKKKWEIYSSLSHNMLGTGPHQSISVLYSVISRKTTTP---CIGPEIVTIDFFWENDISI 1103
+ + E + ++L HQ+++VL+ SRK+ C+ P +V++ ++ ++D++I
Sbjct: 663 IVET-EKQPFRAKDVLDPRVHQTLAVLFGSFSRKSPNAPYFCVRPWVVSMQYYKDHDMTI 721
Query: 1104 GQFIENVVATAFRPC-ADGCGGLMIDHYRSYAHGNGKLDVIIERLQSKMPMLKN----LI 1158
G+F+ C + C M+DH R +G +++ + + +++ I
Sbjct: 722 GEFLVKFCFNRSYECPSSNCEVPMLDHSRKLVYGKVCVEISTQTVNEAENAIESEQQKSI 781
Query: 1159 LTWSYCKKCGLSSPTLQLSEKSWNYSLGKYLELMFWS--SPKNINSIGN---CTHDVAKD 1213
+TW C KC SS ++ + W+ S K+LE + S + I I N C+H +
Sbjct: 782 MTWRNCGKCNCSSQMVKFDKAIWHLSFAKFLEYIGNSCFTTDTIYPITNQNQCSHCFFHE 841
Query: 1214 HLKYFSLNDLVVRMEYSGIDVHELI 1238
L +F++++LV + I + ++
Sbjct: 842 KLYFFAMDNLVTTFKVIAIRPYSVV 866
Score = 79.0 bits (193), Expect = 8e-14
Identities = 39/106 (36%), Positives = 56/106 (52%), Gaps = 5/106 (4%)
Query: 250 MKDESAKECFNCAKPFTTFRRKHHCRICGQIFCSS-CSFLITGESFGYSGRMRICGKCYE 308
M D + +EC+ C + FTTFRR+HHCR+CGQIFC+ CS I G + GY G +R+C C
Sbjct: 1 MPDSTGRECYQCEERFTTFRRRHHCRLCGQIFCAKCCSSHIDGAALGYMGELRLCDYCAR 60
Query: 309 HSMNYXXXXXXXXXXXIIHDQ--VSSRNI--DDDAPSLNNDDIQSI 350
Q V+SR I D + N+D ++++
Sbjct: 61 KVQRLAEEGKQTPTTSTTRSQTPVNSRKISFDRNTAHKNSDTVRTV 106
>7302711 [T] KOG0230 Phosphatidylinositol-4-phosphate 5-kinase and related
FYVE finger-containing proteins
Length = 1809
Score = 226 bits (575), Expect = 4e-58
Identities = 114/243 (46%), Positives = 163/243 (66%), Gaps = 3/243 (1%)
Query: 1807 QSLSRCIKWDSSGGKSGSAFLKTLDDRFVIKELSHSELDAFINFSSSYFEYMSQALFHDL 1866
+SL + ++W++ GGKSGS F KTLDDRFV+KE++ ++ F F+ YFEY+ +
Sbjct: 1563 RSLCKSVQWEARGGKSGSRFCKTLDDRFVLKEMNSRDMTIFEPFAPKYFEYIDRCQQQQQ 1622
Query: 1867 PTALAKILGFYQIQIRNAATGKSFKMDVIIMENLFYEKKTSRIFDLKGSMRNRHVEQTGK 1926
PT LAKI G +++ ++ + + V++MENLFY FDLKGS RNR V+ + +
Sbjct: 1623 PTLLAKIFGVFRVSVKKKDS--FVERSVMVMENLFYGCNIENKFDLKGSERNRLVDPSNQ 1680
Query: 1927 ENE-VLLDENMVEYIYESPIFVREYDKKLLRASLWNDTLFLAKMNVMDYSLVVGVDNQTH 1985
+ E VLLDEN+V+ + P++V + K +LR ++ D+ FL K VMDYSL+VG+D +
Sbjct: 1681 QGEIVLLDENLVQMSWSKPLYVLSHSKTVLRDAIQRDSSFLEKNLVMDYSLLVGLDKKNG 1740
Query: 1986 SLTVGIIDCIRTFTWDKKLESWVKEKGLVGGSTKEPTVVTPRQYKNRFREAMDRYILMVP 2045
L +GIID IRTFT DK++ES +K G++GG K+PTVV P +YK RF +AMDRY L VP
Sbjct: 1741 VLVLGIIDYIRTFTLDKRVESIIKGSGILGGKGKDPTVVNPERYKQRFIDAMDRYFLTVP 1800
Query: 2046 DPW 2048
D W
Sbjct: 1801 DRW 1803
Score = 192 bits (488), Expect = 5e-48
Identities = 230/1067 (21%), Positives = 426/1067 (39%), Gaps = 167/1067 (15%)
Query: 620 QNPQLQKQKYDSNSKDARKSILNSSTWRRISLDKREELNDVCKLHLEALLQQALTDQEIP 679
Q P+ Q + K+ + N + + + L C+ H E LL Q L +
Sbjct: 422 QPPKSMDQSAEEKEKELENELENDRCYTTAT---SKLLASYCE-HEEQLLAQMLRAHNLD 477
Query: 680 GEGDWIAIFNKMIGQIQGIPLDARKAGDLDFKQQHVKIKRLPGGSVLDSMILNGVLYSKG 739
E W + + + DL + +V K++PGG DS I++GV +SK
Sbjct: 478 QE--WDKVLQMLCSTAANHFKPEHCSNDLMDIRNYVNFKKVPGGRRKDSKIVHGVAFSKN 535
Query: 740 LPLKTMPRVVMNPRILLIMFPLEYQKHNNHVISIESVVAQEKEYLKKLVLRLQSLNPDII 799
+ K M V PRILL+ P+ Y++ ++IE+V+ QEKEYL+ + R+ S P+++
Sbjct: 536 VAHKDMATHVPFPRILLLQCPIVYERIEGKFVTIETVLLQEKEYLRNVCARIMSFKPNVV 595
Query: 800 LTGTSASGYALQLFQEVGIVVQCNVKPQVIERISRFTGCDIVITMDKLSSNIKLGTCERF 859
L + +G A L + + + +VK V+ER+SR CDIV +++ + KLG C F
Sbjct: 596 LVHKNVAGIAQDLLRSYEVTLVLDVKLSVMERLSRTLQCDIVSSIESNITMPKLGYCNDF 655
Query: 860 EVRTYIYGNLSKNYTFITGCKTQAGITLVLRGNTSEVLRKVKDVAEFVAYAVFSMKLESS 919
+R Y K F G T +LRG ++ L +VK VA + +A ++ +LE S
Sbjct: 656 YIRNY----NGKTLMFFEKLTNPRGYTCLLRGGSNAELTRVKRVASALLFARYNWRLEMS 711
Query: 920 FFNDNFLQ---------------------LNIEAYKHIQLLKKQNESFTGFFADFIEKF- 957
F + F Q + + + I L +K + T ++ + F
Sbjct: 712 FLLNEFAQPLSPKPSIFDSKETSPKTETEAELRSKRPIILERKSEDKITTIVSENVSDFT 771
Query: 958 --------------------------------------NRRILSVSPIVEFPVPYL-LQK 978
+ +LSVSP + FP+PYL ++
Sbjct: 772 DPLRASQAEALSTSPCAPPVVEALAVEPRYDNRFRTALSSTLLSVSPFLTFPLPYLETEQ 831
Query: 979 ARDVEQQLIEKTALVKKLQDCAEILEYKDSI-----------------------DLSKMQ 1015
R + + + L Q LE DS+ D M+
Sbjct: 832 GRKCKLRKLFPAELYFSKQWSRTGLERPDSMGDGEAGKSEPGNKENQMQLLPAHDFVLMK 891
Query: 1016 LETALTQRD-------FKYLIGFINNKECDAL---KLQFETLKKKWEI-YSSLSHNMLGT 1064
+ + RD F+ G + + L K E +++ ++ L + L
Sbjct: 892 ITAPASSRDIQSKLAEFRSFGGRLPKGKAPMLRPKKKNAEVIQRPQKVSEEQLYKDALDP 951
Query: 1065 GPHQSISVLYSVI---SRKTTTPCIGPEIVTIDFFWENDISIGQFIENVVATAFRPCADG 1121
HQ + VL+ + ++ C P ++ + F+ + DI + QF++ F
Sbjct: 952 QNHQRLPVLFCSFHYNPKGVSSFCKLPMLLDMKFYGQYDIMLEQFLQR-YCCLFNSMCPS 1010
Query: 1122 CGGLMIDHYRSYAHGNGKLDVIIERLQSKMPMLKNLILTWSYCKKCGLSSPTLQLSEKSW 1181
C M+ H R Y H G + V + ++ + +W C C ++PT+ LS+ +
Sbjct: 1011 CNLPMLGHVRRYVHSLGCVHVYLTEDLTRSDPTRIYFTSW--CSICNATTPTIPLSDAAK 1068
Query: 1182 NYSLGKYLELMFWS------SPKNINSIGN--CTHDVAKDHLKYFSLNDLVVRMEYSGID 1233
SL KYLE+ F P G C H + +D++ +FS + + +Y+ ++
Sbjct: 1069 CLSLAKYLEMRFHGHAYKRRPPSTDAEQGGTVCEHSLHRDYVHHFSFRGVGAKFQYTPVE 1128
Query: 1234 VHELITPTATITWNPGKDIKLKVELYYQILEKIDAFYGSVLERLNKLKIDSINDLKLNEA 1293
V E P+ T+ + + + Q+ E+I F E N++ + I DL E
Sbjct: 1129 VWETDLPSLTVQLDLPQPFQSA-----QVQEEIKNFSIKGHEVYNRIH-ERIADLATEEE 1182
Query: 1294 KERIVQ-LKVLVEDEKSTLGANMETIYTGLEGDQHLQLNSIVRALHDNAAGWDNEFVEFE 1352
+VQ LK ++ ++ +E ++T L ++ ++ D A E
Sbjct: 1183 NSPLVQHLKTMLTHDQFIFKQKIEIVHTLLTDNRATAYDT-----SDALAMARRALAESI 1237
Query: 1353 KEFLPTEKDIARITALQLKKMFTDFNKMTEDNG---IKEINGEDAEAEEKSKCMDTTSEE 1409
+ + P ++I ++TA Q + D+G +E+ E + + SK ++ +
Sbjct: 1238 ELWGPRLQEIEKLTAKQAHHI---------DSGTICTEELRPEQVQTADSSKVTTSSLPK 1288
Query: 1410 QR-------SDEESDASPPKPKSVQNAELPLIKSATTNTFSEETIGKVTGPRKQSMTSSL 1462
+ D E+ AS + +N + + ++T N +S+ K+S+ L
Sbjct: 1289 ENDPLECPSEDTETGASNSQTVLDKNFSIDQMLASTVNVYSD----------KKSIRKIL 1338
Query: 1463 DRNLIRKNSNNSTYTQSSKDRNSDTKVGQLANFFDQIHFDSV----TREFELQREMERLH 1518
+ L N N + + +G + + SV + Q+ ++
Sbjct: 1339 TQLLPSGNQVNPLQSPFPAQDHLTLPLGSIPIHVRETDLSSVIAYSLTSMDYQKAIDEAE 1398
Query: 1519 MNKTKYQAMRAKSLKPLVEIYKNVQDAVEEPINVDKGAKNQNSLVNS 1565
N A + LK + + ++V DA + P ++ + + N ++ N+
Sbjct: 1399 ANSN--AAHSSPQLKRKIPLAESVSDAEDSP-SLSRTSSNTSAAPNA 1442
Score = 79.0 bits (193), Expect = 8e-14
Identities = 30/62 (48%), Positives = 44/62 (70%), Gaps = 1/62 (1%)
Query: 246 KEYWMKDESAKECFNCAKPFTTFRRKHHCRICGQIFCSS-CSFLITGESFGYSGRMRICG 304
+ +WM D AKEC++C++ F+TFRRKHHCR+CGQIFCS C+ ++ G G +++C
Sbjct: 180 QRFWMPDSKAKECYDCSQKFSTFRRKHHCRLCGQIFCSKCCNQVVPGMIIRCDGDLKVCN 239
Query: 305 KC 306
C
Sbjct: 240 YC 241
>YJL014w [O] KOG0364 Chaperonin complex component TCP-1 gamma subunit (CCT3)
Length = 534
Score = 90.9 bits (224), Expect = 2e-17
Identities = 59/201 (29%), Positives = 109/201 (53%), Gaps = 12/201 (5%)
Query: 707 DLDFKQQHVKIKRLPGGSVLDSMILNGVLYSKGLPLKTMPRVVMNPRILLIMFPLEYQKH 766
++D K+ +V+++++PGG VLDS +L GVL +K + M R + NPR++L+ PLEY+K
Sbjct: 197 EIDIKR-YVRVEKIPGGDVLDSRVLKGVLLNKDVVHPKMSRHIENPRVVLLDCPLEYKKG 255
Query: 767 NNHV-ISIES------VVAQEKEYLKKLVLRLQSLNPDIILTGTSASGYALQLFQEVGIV 819
+ I IE ++ E+E ++ + ++ ++ P +++T S A + G
Sbjct: 256 ESQTNIEIEKEEDWNRILQIEEEQVQLMCEQILAVRPTLVITEKGVSDLAQHYLLKGGCS 315
Query: 820 VQCNVKPQVIERISRFTGCDIVITMDKLSSNIKLGTCERFEVRTYIYGNLSKNYTFITGC 879
V VK RI+R TG IV ++ L + C F+V + G+ + ++F+ C
Sbjct: 316 VLRRVKKSDNNRIARVTGATIVNRVEDLKESDVGTNCGLFKVE--MIGD--EYFSFLDNC 371
Query: 880 KTQAGITLVLRGNTSEVLRKV 900
K T++LRG + ++L ++
Sbjct: 372 KEPKACTIMLRGGSKDILNEI 392
>SPBC1A4.08c [O] KOG0364 Chaperonin complex component TCP-1 gamma subunit (CCT3)
Length = 528
Score = 87.0 bits (214), Expect = 3e-16
Identities = 57/202 (28%), Positives = 106/202 (52%), Gaps = 12/202 (5%)
Query: 707 DLDFKQQHVKIKRLPGGSVLDSMILNGVLYSKGLPLKTMPRVVMNPRILLIMFPLEYQK- 765
++D K+ + +++++PGG + S +L+GV+ +K + M R + NPRI+L+ PLEY+K
Sbjct: 190 EIDIKR-YARVEKVPGGEIESSCVLDGVMLNKDVTHPKMRRRIENPRIVLLDCPLEYRKG 248
Query: 766 --HNNHVISIES----VVAQEKEYLKKLVLRLQSLNPDIILTGTSASGYALQLFQEVGIV 819
N IS ++ ++ E+E +K++ + ++ PD+++T S A + I
Sbjct: 249 ESQTNIEISKDTDWNRILEIEEEQVKRMCDYIIAVKPDLVITEKGVSDLAQHYLLKANIT 308
Query: 820 VQCNVKPQVIERISRFTGCDIVITMDKLSSNIKLGTCERFEVRTYIYGNLSKNYTFITGC 879
+ RI+R G +IV ++ L C F YI + YTF+TGC
Sbjct: 309 ALRRTRKSDNNRIARACGANIVNRLEDLREKDVGTGCGLF----YIDKLGDEYYTFLTGC 364
Query: 880 KTQAGITLVLRGNTSEVLRKVK 901
K T++LRG + +++ +V+
Sbjct: 365 KNPKACTILLRGPSKDIINEVE 386
>At5g26360 [O] KOG0364 Chaperonin complex component TCP-1 gamma subunit (CCT3)
Length = 555
Score = 85.1 bits (209), Expect = 1e-15
Identities = 57/204 (27%), Positives = 108/204 (52%), Gaps = 15/204 (7%)
Query: 707 DLDFKQQHVKIKRLPGGSVLDSMILNGVLYSKGLPLK-TMPRVVMNPRILLIMFPLEYQK 765
++D K+ ++K++++PGG DS +L GV+++K + M R ++NPRI+L+ PLEY+K
Sbjct: 191 EVDIKK-YIKVEKVPGGQFEDSEVLKGVMFNKDVVAPGKMKRKIVNPRIILLDCPLEYKK 249
Query: 766 HNNHVISI-------ESVVAQEKEYLKKLVLRLQSLNPDIILTGTSASGYALQLFQEVGI 818
N + E ++ E+EY++ + +++ PD+++T S A F + G+
Sbjct: 250 GENQTNAELVREEDWEVLLKLEEEYIENICVQILKFKPDLVITEKGLSDLACHYFSKAGV 309
Query: 819 VVQCNVKPQVIERISRFTGCDIVITMDKLSSNIKLGT-CERFEVRTYIYGNLSKNYTFIT 877
++ RI++ G IV D+L + +GT FEV+ ++FI
Sbjct: 310 SAIRRLRKTDNNRIAKACGAVIVNRPDELQES-DIGTGAGLFEVKKI----GDDFFSFIV 364
Query: 878 GCKTQAGITLVLRGNTSEVLRKVK 901
CK T++LRG + + + +V+
Sbjct: 365 DCKEPKACTVLLRGPSKDFINEVE 388
>Hs5174727 [O] KOG0364 Chaperonin complex component TCP-1 gamma subunit (CCT3)
Length = 544
Score = 84.3 bits (207), Expect = 2e-15
Identities = 58/220 (26%), Positives = 108/220 (48%), Gaps = 12/220 (5%)
Query: 689 NKMIGQIQGIPLDARKAGDLDFKQQHVKIKRLPGGSVLDSMILNGVLYSKGLPLKTMPRV 748
N + ++ + + ++D K+ + +++++PGG + DS +L GV+ +K + M R
Sbjct: 173 NIALDAVKMVQFEENGRKEIDIKK-YARVEKIPGGIIEDSCVLRGVMINKDVTHPRMRRY 231
Query: 749 VMNPRILLIMFPLEYQKHNNHV---ISIES----VVAQEKEYLKKLVLRLQSLNPDIILT 801
+ NPRI+L+ LEY+K + I+ E ++ E+EY+++L + L PD+++T
Sbjct: 232 IKNPRIVLLDSSLEYKKGGSQTDIEITREEDFTRILQMEEEYIQQLCEDIIQLKPDVVIT 291
Query: 802 GTSASGYALQLFQEVGIVVQCNVKPQVIERISRFTGCDIVITMDKLSSNIKLGTCERFEV 861
S A I V+ RI+R G IV ++L + E+
Sbjct: 292 EKGISDLAQHYLMRANITAIRRVRKTDNNRIARACGARIVSRPEELREDDVGTGAGLLEI 351
Query: 862 RTYIYGNLSKNYTFITGCKTQAGITLVLRGNTSEVLRKVK 901
+ + +TFIT CK T++LRG + E+L +V+
Sbjct: 352 KKI----GDEYFTFITDCKDPKACTILLRGASKEILSEVE 387
>Hs20539011 [O] KOG0364 Chaperonin complex component TCP-1 gamma subunit (CCT3)
Length = 544
Score = 84.3 bits (207), Expect = 2e-15
Identities = 58/220 (26%), Positives = 108/220 (48%), Gaps = 12/220 (5%)
Query: 689 NKMIGQIQGIPLDARKAGDLDFKQQHVKIKRLPGGSVLDSMILNGVLYSKGLPLKTMPRV 748
N + ++ + + ++D K+ + +++++PGG + DS +L GV+ +K + M R
Sbjct: 173 NIALDAVKMVQFEENGRKEIDIKK-YARVEKIPGGIIEDSCVLRGVMINKDVTHPRMRRY 231
Query: 749 VMNPRILLIMFPLEYQKHNNHV---ISIES----VVAQEKEYLKKLVLRLQSLNPDIILT 801
+ NPRI+L+ LEY+K + I+ E ++ E+EY+++L + L PD+++T
Sbjct: 232 IKNPRIVLLDSSLEYKKGESQTDIEITREEDFTRILQMEEEYIQQLCEDIIQLKPDVVIT 291
Query: 802 GTSASGYALQLFQEVGIVVQCNVKPQVIERISRFTGCDIVITMDKLSSNIKLGTCERFEV 861
S A I V+ RI+R G IV ++L + E+
Sbjct: 292 EKGISDLAQHYLMRANITAIRRVRKTDNNRIARACGARIVSRPEELREDDVGTGAGLLEI 351
Query: 862 RTYIYGNLSKNYTFITGCKTQAGITLVLRGNTSEVLRKVK 901
+ + +TFIT CK T++LRG + E+L +V+
Sbjct: 352 KKI----GDEYFTFITDCKDPKACTILLRGASKEILSEVE 387
>7300184 [O] KOG0364 Chaperonin complex component TCP-1 gamma subunit (CCT3)
Length = 544
Score = 83.2 bits (204), Expect = 4e-15
Identities = 59/245 (24%), Positives = 122/245 (49%), Gaps = 15/245 (6%)
Query: 682 GDWIAIFNKM-IGQIQGIPLDARKAGDLDFKQQHVKIKRLPGGSVLDSMILNGVLYSKGL 740
G W + K+ + ++ + L ++D K+ + K++++PGG++ +S +L GV+ +K +
Sbjct: 168 GKWSDLAVKIALDAVETVTLSENGRLEVDIKR-YAKVEKIPGGAIEESCVLKGVMINKDV 226
Query: 741 PLKTMPRVVMNPRILLIMFPLEYQKHNNHVISIESVVAQ--------EKEYLKKLVLRLQ 792
M R++ NPRI+L+ LEY+K + ++E + Q E+E+++++ +
Sbjct: 227 THPKMRRLIENPRIVLLDCSLEYKKGESQT-NVEIIGEQDFTRMLQIEEEFVQRICADII 285
Query: 793 SLNPDIILTGTSASGYALQLFQEVGIVVQCNVKPQVIERISRFTGCDIVITMDKLSSNIK 852
++ PD++ T S A + GI ++ RI+R G IV ++L+
Sbjct: 286 AVKPDLVFTEKGVSDLAQHYLLKAGITAIRRLRKTDNLRIARACGATIVNRTEELTEKDV 345
Query: 853 LGTCERFEVRTYIYGNLSKNYTFITGCKTQAGITLVLRGNTSEVLRKVKDVAEFVAYAVF 912
FEV+ + +TF+T CK T++LRG + ++L + + + +
Sbjct: 346 GTGAGLFEVKKI----GDEYFTFVTECKEPKACTILLRGASKDILNETERNLQDALHVAR 401
Query: 913 SMKLE 917
++ LE
Sbjct: 402 NLVLE 406
>At1g10900 [T] KOG0229 Phosphatidylinositol-4-phosphate 5-kinase
Length = 859
Score = 79.3 bits (194), Expect = 6e-14
Identities = 56/165 (33%), Positives = 88/165 (52%), Gaps = 14/165 (8%)
Query: 1817 SSGGKSGSAFLKTLDDRFVIKELSHSELDAFINFSSSYFEYMSQALFHDLPTALAKILGF 1876
SS GKSGS F + DDRFVIK L SEL + Y+E++ H+ T + K G
Sbjct: 532 SSPGKSGSIFYLSHDDRFVIKTLKKSELQVLLRMLPKYYEHVGD---HE-NTLITKFFGV 587
Query: 1877 YQIQIRNAATGKSFKMDVIIMENLF-YEKKTSRIFDLKGSMRNRHVEQTGKENEVLLDEN 1935
++I ++ GK K+ ++M N+F E K R +DLKGS + R E+ + + L +
Sbjct: 588 HRITLK---WGK--KVRFVVMGNMFCTELKIHRRYDLKGSTQGRFTEKIKIQEKTTLKDL 642
Query: 1936 MVEYIYESPIFVREYDKKLLRASLWNDTLFLAKMNVMDYSLVVGV 1980
+ Y + +RE L ++ D FL +N++DYSL++G+
Sbjct: 643 DLAYEFHMDKLLRE----ALFKQIYLDCSFLESLNIIDYSLLLGL 683
>ECU10g0240 [O] KOG0364 Chaperonin complex component TCP-1 gamma subunit (CCT3)
Length = 519
Score = 75.9 bits (185), Expect = 6e-13
Identities = 56/198 (28%), Positives = 104/198 (52%), Gaps = 13/198 (6%)
Query: 712 QQHVKIKRLPGGSVLDSMILNGVLYSKGLPLKTMPRVVMNPRILLIMFPLEYQK---HNN 768
+ ++K++++ GG++++S +++GVL +K + M RV+ NPRI++I PLEY+K N
Sbjct: 191 KNNMKVEKVLGGNLMESEVVDGVLINKDIIHPQMRRVIENPRIVIIESPLEYKKGESQTN 250
Query: 769 HVISIES----VVAQEKEYLKKLVLRLQSLNPDIILTGTSASGYALQLFQEVGIVVQCNV 824
+ S E+ + E+E ++++ R+ + PDI++ S AL + E I +
Sbjct: 251 YEFSKENDFTRALEIEEEQVREMCERIIGVRPDIVVCEKGISDLALSILFENNITGLRRL 310
Query: 825 KPQVIERISRFTGCDIVITMDKLSSNIKLGTCERFEVRTYI-YGNLSKNYTFITGCKTQA 883
K I R+S+ G V + L +C FE YI YG + Y + C
Sbjct: 311 KKTDISRLSKVCGARSVSRPEDLEERHVGVSCGLFE---YIKYG--EEYYCKFSRCAHPK 365
Query: 884 GITLVLRGNTSEVLRKVK 901
++V+RG T ++L +++
Sbjct: 366 ACSVVIRGPTKDILDELE 383
>CE25900 [O] KOG0364 Chaperonin complex component TCP-1 gamma subunit (CCT3)
Length = 606
Score = 75.9 bits (185), Expect = 6e-13
Identities = 55/218 (25%), Positives = 104/218 (47%), Gaps = 13/218 (5%)
Query: 689 NKMIGQIQGIPLDARKAGDLDFKQQHVKIKRLPGGSVLDSMILNGVLYSKGLPLKTMPRV 748
N I ++ I ++ ++D K+ + +I+++PGG + DS ++ G++ +K + M R
Sbjct: 177 NISIQAVKTIRVEKAGVREIDIKR-YCRIEKIPGGRIEDSQVVKGIVVNKDILHAKMRRR 235
Query: 749 VMNPRILLIMFPLEYQKHNNHVI-------SIESVVAQEKEYLKKLVLRLQSLNPDIILT 801
+ NPRI+L+ LEY+K + I +++ QE++ ++K + L PD++ T
Sbjct: 236 IENPRIVLLDCNLEYKKGESQTSLEIMREEDISAILEQEEQAIRKQCDEIIKLKPDLVFT 295
Query: 802 GTSASGYALQLFQEVGIVVQCNVKPQVIERISRFTGCDIVITMDKLSSNIKLGTCERFEV 861
S A + GI +K R++R G +V L + FEV
Sbjct: 296 EKGISDLAQHFLLKAGITCLRRLKKTDNNRLARVCGARVVHDTSDLRDEDVGTKAQLFEV 355
Query: 862 RTYIYGNLSKNYTFITGCKTQAGITLVLRGNTSEVLRK 899
+ YT++T +T T+VLRG + +V+ +
Sbjct: 356 VKI----ADEYYTYVT-AETTTACTVVLRGPSKDVINE 388
>ECU10g0630 [O] KOG0361 Chaperonin complex component TCP-1 eta subunit (CCT7)
Length = 511
Score = 75.1 bits (183), Expect = 1e-12
Identities = 72/269 (26%), Positives = 123/269 (44%), Gaps = 42/269 (15%)
Query: 655 EELNDVCKLHLEALLQQ------------ALTDQEIPGEGDWIAIFNKMIGQIQGIPLDA 702
EEL +C HLE + + +T + I E ++ F++MI +DA
Sbjct: 123 EELRMMCIEHLEKMGMELDDEVLYKLAGTCITSKNIRHEKEY---FSRMI-------VDA 172
Query: 703 RKAGDLDFKQQHVKIKRLPGGSVLDSMILNGVLYSKGLP---LKTMPRVVMNPRILLIMF 759
K +D + + +K++ GGS+ DS+ +NG+ + K + P+ ++NPRIL +
Sbjct: 173 VKQAKID-DAESIGVKKVQGGSIGDSVAVNGIAFEKCFTYAGYEQQPKRILNPRILCLNV 231
Query: 760 PLEYQKHNNH-------VISIESVVAQEKEYLKKLVLRLQSLNPDIILTGTSASGYALQL 812
LE++ ++ V + VV E +++ + + S +++L+ S YA Q
Sbjct: 232 ELEWKSERDNAEIRVGGVEEYQRVVDAEWAIIRRKLDEIISSGANVVLSSLSIGDYATQY 291
Query: 813 FQEVGIVVQCNVKPQVIERISRFTGCDIVITMDKLSSNIKLGTCERFEVRTYIYGNLSK- 871
F + GI V + + R+ G I+ D L + LG C FE R L K
Sbjct: 292 FAKHGIFCAGRVSKEDLGRVVGSCGGSILGATDYLEGS--LGACALFEER-----QLGKF 344
Query: 872 NYTFITGCKTQAGITLVLRGNTSEVLRKV 900
Y + G T A T++LRG EVL ++
Sbjct: 345 RYNYFEGGGTSA-CTMILRGPGQEVLEEI 372
>At1g60890 [T] KOG0229 Phosphatidylinositol-4-phosphate 5-kinase
Length = 769
Score = 74.7 bits (182), Expect = 1e-12
Identities = 56/169 (33%), Positives = 88/169 (51%), Gaps = 22/169 (13%)
Query: 1817 SSGGKSGSAFLKTLDDRFVIKELSHSELDAFINFSSSYFEYMSQALFHDLPTALAKILGF 1876
SS GKSGS F + DDRFVIK L SEL + Y+E++ T + K G
Sbjct: 444 SSPGKSGSIFYLSHDDRFVIKTLKRSELKVLLRMLPRYYEHVGDY----ENTLITKFFGV 499
Query: 1877 YQIQIRNAATGKSFKMDVIIMENLF-YEKKTSRIFDLKGSMRNRHVEQTGKENEVLLDEN 1935
++I+++ GK K+ ++M N+F E K R +DLKGS + R+ E+ + L +
Sbjct: 500 HRIKLK---WGK--KVRFVVMGNMFCTELKIHRRYDLKGSTQGRYTEKNKIGEKTTLKDL 554
Query: 1936 MVEYIYESPIFVREYDKKLLRASLWN----DTLFLAKMNVMDYSLVVGV 1980
+ Y + + KLLR +L+ D FL + ++DYSL++G+
Sbjct: 555 DLAYEF--------HMDKLLREALFKQIILDCSFLESLQILDYSLLLGL 595
>Hs6857820 [T] KOG0229 Phosphatidylinositol-4-phosphate 5-kinase
Length = 406
Score = 73.9 bits (180), Expect = 2e-12
Identities = 56/194 (28%), Positives = 100/194 (50%), Gaps = 15/194 (7%)
Query: 1791 FDAFRKKCGCGEENFIQSLSRCIKW-DSSGGKSGSAFLKTLDDRFVIKELSHSELDAFIN 1849
F R++ G +++F SL+R + S +SG+ F + D R++IK ++ ++ N
Sbjct: 98 FRNLRERFGIDDQDFQNSLTRSAPLPNDSQARSGARFHTSYDKRYIIKTITSEDVAEMHN 157
Query: 1850 FSSSYFEYMSQALFHDLPTALAKILGFYQIQIRNAATGKSFKMDVIIMENLFYEK-KTSR 1908
Y +Y+ + H + T L + LG Y++ + ++ VI+ N+F + R
Sbjct: 158 ILKKYHQYIVEC--HGI-TLLPQFLGMYRLNVDGV------EIYVIVTRNVFSHRLSVYR 208
Query: 1909 IFDLKGSMRNRHVEQTGKENEV-LLDENMVEYIYESP-IFVREYDKKLLRASLWNDTLFL 1966
+DLKGS R K E+ L +N ++I E I++ + +KK+ L D FL
Sbjct: 209 KYDLKGSTVAREASDKEKAKELPTLKDN--DFINEGQKIYIDDNNKKVFLEKLKKDVEFL 266
Query: 1967 AKMNVMDYSLVVGV 1980
A++ +MDYSL+VG+
Sbjct: 267 AQLKLMDYSLLVGI 280
>7304346 [T] KOG0229 Phosphatidylinositol-4-phosphate 5-kinase
Length = 313
Score = 73.9 bits (180), Expect = 2e-12
Identities = 62/195 (31%), Positives = 99/195 (49%), Gaps = 17/195 (8%)
Query: 1791 FDAFRKKCGCGEENFIQSLSRC--IKWDSSGGKSGSAFLKTLDDRFVIKELSHSELDAFI 1848
F R++ G + ++ +SL+R I+ DSSG KSG+ F ++ D F+IK L+ E++
Sbjct: 96 FRNLRERFGVDDVDYRESLTRSQPIQIDSSG-KSGAQFYQSYDKFFIIKSLTSEEIERMH 154
Query: 1849 NFSSSYFEYMSQALFHDLPTALAKILGFYQIQIRNAATGKSFKMDVIIMENLFYEKKT-S 1907
F Y Y+ + T L + LG Y+I T +S + ++M N+F T
Sbjct: 155 AFLKQYHPYVVE---RHGKTLLPQYLGMYRI------TVESVQYYFVVMRNVFSSHLTIH 205
Query: 1908 RIFDLKGSMRNRHVEQTGKENEV--LLDENMVEYIYESPIFVREYDKKLLRASLWNDTLF 1965
+ FDLKGS +R + E + D + ++ + I DK L +L ND
Sbjct: 206 KKFDLKGSTVDREASEKELEKNLPTFKDNDFIKQKVKLDIGKEAKDK--LMDTLSNDVDL 263
Query: 1966 LAKMNVMDYSLVVGV 1980
L K+++MDYSL+VGV
Sbjct: 264 LTKLHIMDYSLLVGV 278
>Hs21322230 [T] KOG0229 Phosphatidylinositol-4-phosphate 5-kinase
Length = 421
Score = 73.2 bits (178), Expect = 4e-12
Identities = 52/191 (27%), Positives = 96/191 (50%), Gaps = 12/191 (6%)
Query: 1791 FDAFRKKCGCGEENFIQSLSRCIKWDSSGGKSGSAFLKTLDDRFVIKELSHSELDAFINF 1850
F R + G +++++ SL+R +S G S FL + D VIKE+S ++ +
Sbjct: 108 FRNLRDRFGIDDQDYLVSLTRNPPSESEG--SDGRFLISYDRTLVIKEVSSEDIADMHSN 165
Query: 1851 SSSYFEYMSQALFHDLPTALAKILGFYQIQIRNAATGKSFKMDVIIMENLFYEK-KTSRI 1909
S+Y +Y+ + + T L + LG Y++ + N + +++M N+F + R
Sbjct: 166 LSNYHQYIVKCHGN---TLLPQFLGMYRVSVDNEDSY------MLVMRNMFSHRLPVHRK 216
Query: 1910 FDLKGSMRNRHVEQTGKENEVLLDENMVEYIYESPIFVREYDKKLLRASLWNDTLFLAKM 1969
+DLKGS+ +R K E+ +M +++ E +KK+ L D FL ++
Sbjct: 217 YDLKGSLVSREASDKEKVKELPTLRDMDFLNKNQKVYIGEEEKKIFLEKLKRDVEFLVQL 276
Query: 1970 NVMDYSLVVGV 1980
+MDYSL++G+
Sbjct: 277 KIMDYSLLLGI 287
>At3g09920 [T] KOG0229 Phosphatidylinositol-4-phosphate 5-kinase
Length = 815
Score = 73.2 bits (178), Expect = 4e-12
Identities = 51/168 (30%), Positives = 87/168 (51%), Gaps = 14/168 (8%)
Query: 1817 SSGGKSGSAFLKTLDDRFVIKELSHSELDAFINFSSSYFEYMSQALFHDLPTALAKILGF 1876
SS GKSGS F + DDRF+IK L SE+ + Y ++ T + K G
Sbjct: 489 SSPGKSGSVFFLSQDDRFMIKTLRKSEVKVLLRMLPDYHHHVKTY----ENTLITKFFGL 544
Query: 1877 YQIQIRNAATGKSFKMDVIIMENLFY-EKKTSRIFDLKGSMRNRHVEQTGKENEVLLDEN 1935
++I+ ++G+ F+ ++M N+F+ + + R FDLKGS R ++ + +L +
Sbjct: 545 HRIK---PSSGQKFRF--VVMGNMFFTDLRIHRRFDLKGSSLGRSADKVEIDENTILKDL 599
Query: 1936 MVEYIYESPIFVREYDKKLLRASLWNDTLFLAKMNVMDYSLVVGVDNQ 1983
+ Y + F+ ++ L L D+ FL N+MDYSL++GV ++
Sbjct: 600 DLNYSF----FLETSWREGLLRQLEIDSKFLEAQNIMDYSLLLGVHHR 643
>Hs4505819 [T] KOG0229 Phosphatidylinositol-4-phosphate 5-kinase
Length = 416
Score = 71.6 bits (174), Expect = 1e-11
Identities = 54/192 (28%), Positives = 93/192 (48%), Gaps = 11/192 (5%)
Query: 1791 FDAFRKKCGCGEENFIQSLSRCIKWDS-SGGKSGSAFLKTLDDRFVIKELSHSELDAFIN 1849
F R++ G ++++ S++R +S S G+ G+ FL T D RFVIK +S ++ N
Sbjct: 103 FRNLRERFGIDDQDYQNSVTRSAPINSDSQGRCGTRFLTTYDRRFVIKTVSSEDVAEMHN 162
Query: 1850 FSSSYFEYMSQALFHDLPTALAKILGFYQIQIRNAATGKSFKMDVIIMENLFYEKKT-SR 1908
Y +++ + + T L + LG Y++ + T +++ N+F + T R
Sbjct: 163 ILKKYHQFIVECHGN---TLLPQFLGMYRLTVDGVETY------MVVTRNVFSHRLTVHR 213
Query: 1909 IFDLKGSMRNRHVEQTGKENEVLLDENMVEYIYESPIFVREYDKKLLRASLWNDTLFLAK 1968
+DLKGS R K ++ ++ + V E KK L D FLA+
Sbjct: 214 KYDLKGSTVAREASDKEKAKDLPTFKDNDFLNEGQKLHVGEESKKNFLEKLKRDVEFLAQ 273
Query: 1969 MNVMDYSLVVGV 1980
+ +MDYSL+VG+
Sbjct: 274 LKIMDYSLLVGI 285
>Hs4505815 [T] KOG0229 Phosphatidylinositol-4-phosphate 5-kinase
Length = 549
Score = 68.9 bits (167), Expect = 8e-11
Identities = 57/200 (28%), Positives = 95/200 (47%), Gaps = 15/200 (7%)
Query: 1791 FDAFRKKCGCGEENFIQSL-SRCIKWDSSGGKSGSAFLKTLDDRFVIKELSHSELDAFIN 1849
F FR+ G ++++ SL S + S G SGS F + DD F+IK + H E +
Sbjct: 134 FRYFRELFGIRPDDYLYSLCSEPLIELCSSGASGSLFYVSSDDEFIIKTVQHKEAEFLQK 193
Query: 1850 FSSSYFEYMSQALFHDLPTALAKILGFYQIQIRNAATGKSFKMDVIIMENLFYEKKTSRI 1909
Y+ ++Q + T L K G Y +Q A GK+ + +++M NL I
Sbjct: 194 LLPGYYMNLNQ----NPRTLLPKFYGLYCVQ----AGGKNIR--IVVMNNLLPRSVKMHI 243
Query: 1910 -FDLKGSMRNRHVEQTGKENEVLLDENMVEYIYESP--IFVREYDKKLLRASLWNDTLFL 1966
+DLKGS R Q +E + +++ +++ + P +F+ L +L D L L
Sbjct: 244 KYDLKGSTYKRRASQKEREKPLPTFKDL-DFLQDIPDGLFLDADMYNALCKTLQRDCLVL 302
Query: 1967 AKMNVMDYSLVVGVDNQTHS 1986
+MDYSL++ + N H+
Sbjct: 303 QSFKIMDYSLLMSIHNIDHA 322
>At2g41210 [T] KOG0229 Phosphatidylinositol-4-phosphate 5-kinase
Length = 772
Score = 68.6 bits (166), Expect = 1e-10
Identities = 58/172 (33%), Positives = 90/172 (51%), Gaps = 24/172 (13%)
Query: 1817 SSGGKSGSAFLKTLDDRFVIKELSHSELDAFINFSSSYFEYMSQALFHDLPTALAKILGF 1876
SS GKSGS F T DDR++IK + SE + ++Y+ ++ +A + L + + G
Sbjct: 477 SSPGKSGSFFYLTNDDRYMIKTMKKSETKVLLGMLAAYYNHV-RAFENSL---VIRFFGL 532
Query: 1877 YQIQIRNAATGKSFKMDVIIMENLFYEK-KTSRIFDLKGSMRNRHVEQTGKE---NEVL- 1931
+ +++ N T K K+ +IM NLF K R FDLKGS R ++ E N +L
Sbjct: 533 HCVKL-NGPTQK--KVRFVIMGNLFCSKYSVHRRFDLKGSSLGRTTDKPESEIDSNTILK 589
Query: 1932 -LDENMVEYIYES--PIFVREYDKKLLRASLWNDTLFLAKMNVMDYSLVVGV 1980
LD N + + ++ F+R+ DK D FL + +MDYSL+VG+
Sbjct: 590 DLDLNFIFRLQKAWYQEFIRQIDK---------DCEFLEQERIMDYSLLVGI 632
>YJL111w [O] KOG0361 Chaperonin complex component TCP-1 eta subunit (CCT7)
Length = 550
Score = 67.4 bits (163), Expect = 2e-10
Identities = 52/203 (25%), Positives = 91/203 (44%), Gaps = 15/203 (7%)
Query: 709 DFKQQHVKIKRLPGGSVLDSMILNGVLYSKGLP---LKTMPRVVMNPRILLIMFPLEY-- 763
D + + IK++PGG++ +S+ +NGV + K + P+ NP+IL + LE
Sbjct: 193 DLDDKLIGIKKIPGGAMEESLFINGVAFKKTFSYAGFEQQPKKFNNPKILSLNVELELKA 252
Query: 764 QKHN-----NHVISIESVVAQEKEYLKKLVLRLQSLNPDIILTGTSASGYALQLFQEVGI 818
+K N HV +++V E + + + + +++ +I+L+ A Q F + I
Sbjct: 253 EKDNAEVRVEHVEDYQAIVDAEWQLIFEKLRQVEETGANIVLSKLPIGDLATQFFADRNI 312
Query: 819 VVQCNVKPQVIERISRFTGCDIVITMDKLSSNIKLGTCERFEVRTYIYGNLSKNYTFITG 878
V + R+ + G I T + LGTC FE S+ Y G
Sbjct: 313 FCAGRVSADDMNRVIQAVGGSIQSTTSDIKPE-HLGTCALFEEMQI----GSERYNLFQG 367
Query: 879 CKTQAGITLVLRGNTSEVLRKVK 901
C TL+LRG +V+ +V+
Sbjct: 368 CPQAKTCTLLLRGGAEQVIAEVE 390
>CE11121 [T] KOG0229 Phosphatidylinositol-4-phosphate 5-kinase
Length = 619
Score = 67.4 bits (163), Expect = 2e-10
Identities = 56/196 (28%), Positives = 95/196 (47%), Gaps = 15/196 (7%)
Query: 1791 FDAFRKKCGCGEENFIQSL-SRCIKWDSSGGKSGSAFLKTLDDRFVIKELSHSELDAFIN 1849
F FR +F++S+ + +K S+ G SGS F + DD+F+IK + H E D
Sbjct: 150 FRYFRNLFHIKPADFLRSICTEPLKELSNAGASGSIFYVSQDDQFIIKTVQHKEADFLQK 209
Query: 1850 FSSSYFEYMSQALFHDLPTALAKILGFYQIQIRNAATGKSFKMDVIIMENLFYEKKT-SR 1908
Y+ ++Q + T L K G + Q + GK+ ++ ++M NL + T
Sbjct: 210 LLPGYYMNLNQ----NPRTLLPKFFGLFCYQ----SLGKNIRL--LVMNNLLPQTVTMHE 259
Query: 1909 IFDLKGSMRNR--HVEQTGKENEVLLDENMVEYIYESPIFVREYDKKLLRASLWNDTLFL 1966
+D+KGS R + + K + L D + +E ++ IF+ + L S+ D L +
Sbjct: 260 KYDMKGSTYKRMANKAERAKPHPTLKDLDFLEN-HKDGIFIDPTALEALMKSISRDCLVM 318
Query: 1967 AKMNVMDYSLVVGVDN 1982
+MDYSL+VG+ N
Sbjct: 319 ESFKIMDYSLLVGIHN 334
>7291493 [T] KOG0229 Phosphatidylinositol-4-phosphate 5-kinase
Length = 515
Score = 67.4 bits (163), Expect = 2e-10
Identities = 58/203 (28%), Positives = 93/203 (45%), Gaps = 14/203 (6%)
Query: 1784 KIFFFEQFDAFRKKCGCGEENFIQSLSRC-IKWDSSGGKSGSAFLKTLDDRFVIKELSHS 1842
KI+ F FR G ++F+ S+ ++ S+ G SGS F T DD F+IK + H
Sbjct: 135 KIYAPIAFRYFRDLFGIQPDDFMMSMCTSPLRELSNPGASGSIFYLTTDDEFIIKTVQHK 194
Query: 1843 ELDAFINFSSSYFEYMSQALFHDLPTALAKILGFYQIQIRNAATGKSFKMDVIIMENLFY 1902
E + Y+ ++Q + T L K G Y +Q NA + +++M NL
Sbjct: 195 EGEFLQKLLPGYYMNLNQ----NPRTLLPKFFGLYCLQTSNAK-----NIRLVVMNNLLP 245
Query: 1903 EK-KTSRIFDLKGS--MRNRHVEQTGKENEVLLDENMVEYIYESPIFVREYDKKLLRASL 1959
K +DLKGS R + + K++ D + +E + + IF+ L ++
Sbjct: 246 SSVKMHLKYDLKGSTFKRKANKAERAKKSPTYKDLDFMEQ-HPNGIFLEAETYAALIKTI 304
Query: 1960 WNDTLFLAKMNVMDYSLVVGVDN 1982
D L +MDYSL++GV N
Sbjct: 305 QRDCTVLESFKIMDYSLLLGVHN 327
>Hs4505817 [T] KOG0229 Phosphatidylinositol-4-phosphate 5-kinase
Length = 540
Score = 67.0 bits (162), Expect = 3e-10
Identities = 55/201 (27%), Positives = 91/201 (44%), Gaps = 15/201 (7%)
Query: 1791 FDAFRKKCGCGEENFIQSL-SRCIKWDSSGGKSGSAFLKTLDDRFVIKELSHSELDAFIN 1849
F FR+ G ++++ S+ S + S+ G SGS F T DD F+IK + H E +
Sbjct: 91 FRYFRELFGIKPDDYLYSICSEPLIELSNPGASGSLFFVTSDDEFIIKTVQHKEAEFLQK 150
Query: 1850 FSSSYFEYMSQALFHDLPTALAKILGFYQIQIRNAATGKSFKMDVIIMENLFYEKKTSRI 1909
Y+ ++Q + T L K G Y +Q + +++M N+
Sbjct: 151 LLPGYYMNLNQ----NPRTLLPKFYGLYCMQ------SGGINIRIVVMNNVLPRSMRMHF 200
Query: 1910 -FDLKGSMRNRHV--EQTGKENEVLLDENMVEYIYESPIFVREYDKKLLRASLWNDTLFL 1966
+DLKGS R ++ K N D + ++ ++E F E L++ +L D L
Sbjct: 201 TYDLKGSTYKRRASRKEREKSNPTFKDLDFLQDMHEGLYFDTETYNALMK-TLQRDCRVL 259
Query: 1967 AKMNVMDYSLVVGVDNQTHSL 1987
+MDYSL++G+ HSL
Sbjct: 260 ESFKIMDYSLLLGIHFLDHSL 280
>Hs20550114 [T] KOG0229 Phosphatidylinositol-4-phosphate 5-kinase
Length = 512
Score = 65.9 bits (159), Expect = 7e-10
Identities = 57/200 (28%), Positives = 92/200 (45%), Gaps = 15/200 (7%)
Query: 1791 FDAFRKKCGCGEENFIQSL-SRCIKWDSSGGKSGSAFLKTLDDRFVIKELSHSELDAFIN 1849
F FR+ G ++++ SL S + S G SGS F + DD +IK L H E +
Sbjct: 134 FRYFRELFGIPPDDYLCSLCSEPLIELCSSGASGSLFYVSSDDELIIKTLQHKEAEFLQK 193
Query: 1850 FSSSYFEYMSQALFHDLPTALAKILGFYQIQIRNAATGKSFKMDVIIMENLFYEKKTSRI 1909
Y+ +SQ + T L K G Y +Q GK+ + +++M NL I
Sbjct: 194 LLPGYYLNLSQ----NPRTLLPKFFGLYCVQ----TGGKNIR--IVVMNNLLPRSVKMHI 243
Query: 1910 -FDLKGSMRNRHVEQTGKENEVLLDENMVEYIYESP--IFVREYDKKLLRASLWNDTLFL 1966
+DLKGS R Q +E + +++ +++ + P +F+ L +L D L L
Sbjct: 244 KYDLKGSTYKRRASQKEREKPLPTFKDL-DFLQDIPDGLFLDADTYNALCKTLQRDCLVL 302
Query: 1967 AKMNVMDYSLVVGVDNQTHS 1986
+MDYSL + + N H+
Sbjct: 303 QSFKIMDYSLWLSIHNIDHA 322
>At3g56960 [T] KOG0229 Phosphatidylinositol-4-phosphate 5-kinase
Length = 779
Score = 65.9 bits (159), Expect = 7e-10
Identities = 56/172 (32%), Positives = 85/172 (48%), Gaps = 24/172 (13%)
Query: 1817 SSGGKSGSAFLKTLDDRFVIKELSHSELDAFINFSSSYFEYMSQALFHDLPTALAKILGF 1876
SS GKSGS F T DDR++IK + SE + ++Y+ ++ +A + L ++ F
Sbjct: 484 SSPGKSGSFFYLTNDDRYMIKTMKKSETKVLLRMLAAYYNHV-RAFENTL------VIRF 536
Query: 1877 YQIQIRNAATGKSFKMDVIIMENLF-YEKKTSRIFDLKGSMRNRHVEQTGKE---NEVL- 1931
Y + K+ +IM NLF E R FDLKGS R ++ E N +L
Sbjct: 537 YGLHCVKLTGPIQKKVRFVIMGNLFCSEYSIHRRFDLKGSSLGRTTDKPESEINSNTILK 596
Query: 1932 -LDENMVEYIYES--PIFVREYDKKLLRASLWNDTLFLAKMNVMDYSLVVGV 1980
LD N + + ++ F+R+ DK D FL + +MDYSL+VG+
Sbjct: 597 DLDLNFIFRLQKAWYQEFIRQVDK---------DCEFLEQERIMDYSLLVGI 639
>At3g11830 [O] KOG0361 Chaperonin complex component TCP-1 eta subunit (CCT7)
Length = 557
Score = 65.9 bits (159), Expect = 7e-10
Identities = 62/278 (22%), Positives = 122/278 (43%), Gaps = 24/278 (8%)
Query: 700 LDARKAGDLDFKQQHVKIKRLPGGSVLDSMILNGVLYSKGLP---LKTMPRVVMNPRILL 756
+DA A D + + IK++PGG++ DS +++GV + K + P+ +NP+ILL
Sbjct: 183 VDAVMAIGNDDRLNLIGIKKVPGGNMRDSFLVDGVAFKKTFSYAGFEQQPKKFLNPKILL 242
Query: 757 IMFPLEY--QKHNNHV-----ISIESVVAQEKEYLKKLVLRLQSLNPDIILTGTSASGYA 809
+ LE +K N + +S+V E + + + ++L+ + A
Sbjct: 243 LNIELELKSEKENAEIRLSDPSQYQSIVDAEWNIIYDKLDKCVESGAKVVLSRLAIGDLA 302
Query: 810 LQLFQEVGIVVQCNVKPQVIERISRFTGCDIVITMDKLSSNIKLGTCERFEVRTYIYGNL 869
Q F + I V + + R++ G + +++ + + LGTCE FE +
Sbjct: 303 TQYFADRDIFCAGRVAEEDLNRVAAAAGGTVQTSVNNIIDEV-LGTCEIFEEKQV----G 357
Query: 870 SKNYTFITGCKTQAGITLVLRGNTSEVL----RKVKDVAEFVAYAVFSMKLESSFFNDNF 925
+ + +GC + T+VLRG + + R + D V AV K +
Sbjct: 358 GERFNIFSGCPSGRTATIVLRGGADQFIEEAERSLHDAIMIVRRAV---KNSTVVPGGGA 414
Query: 926 LQLNIEAY--KHIQLLKKQNESFTGFFADFIEKFNRRI 961
+ + I Y +H + + +++ F +A +E R++
Sbjct: 415 IDMEISKYLRQHSRTIAGKSQLFINSYAKALEVIPRQL 452
>Hs16193739 [T] KOG0229 Phosphatidylinositol-4-phosphate 5-kinase
Length = 668
Score = 65.5 bits (158), Expect = 9e-10
Identities = 58/196 (29%), Positives = 93/196 (46%), Gaps = 15/196 (7%)
Query: 1791 FDAFRKKCGCGEENFIQSL-SRCIKWDSSGGKSGSAFLKTLDDRFVIKELSHSELDAFIN 1849
F FR+ G ++++ SL + + S+ G SGS F T DD F+IK + H E +
Sbjct: 141 FRYFRELFGIRPDDYLYSLCNEPLIELSNPGASGSLFYVTSDDEFIIKTVMHKEAEFLQK 200
Query: 1850 FSSSYFEYMSQALFHDLPTALAKILGFYQIQIRNAATGKSFKMDVIIMENLFYE-KKTSR 1908
Y+ ++Q + T L K G Y +Q + GK+ + V++M N+ K
Sbjct: 201 LLPGYYMNLNQ----NPRTLLPKFYGLYCVQ----SGGKNIR--VVVMNNILPRVVKMHL 250
Query: 1909 IFDLKGSMRNRHVEQTGKENE--VLLDENMVEYIYESPIFVREYDKKLLRASLWNDTLFL 1966
FDLKGS R + KE D + ++ + E + + L++ +L D L L
Sbjct: 251 KFDLKGSTYKRRASKKEKEKSFPTYKDLDFMQDMPEGLLLDADTFSALVK-TLQRDCLVL 309
Query: 1967 AKMNVMDYSLVVGVDN 1982
+MDYSL++GV N
Sbjct: 310 ESFKIMDYSLLLGVHN 325
>7301552 [R] KOG1819 FYVE finger-containing proteins
Length = 920
Score = 65.1 bits (157), Expect = 1e-09
Identities = 28/65 (43%), Positives = 35/65 (53%), Gaps = 1/65 (1%)
Query: 244 LSKEYWMKDESAKECFNCAKPFTTFRRKHHCRICGQIFCSSCSFLITG-ESFGYSGRMRI 302
LS W+ D A C C PFT FRR+HHCR CG +FC CS +G + +R+
Sbjct: 832 LSPPAWIPDGKAPRCMACQTPFTAFRRRHHCRNCGGVFCGVCSNASAPLPKYGLTKAVRV 891
Query: 303 CGKCY 307
C CY
Sbjct: 892 CRDCY 896
>At1g77740 [T] KOG0229 Phosphatidylinositol-4-phosphate 5-kinase
Length = 754
Score = 64.7 bits (156), Expect = 1e-09
Identities = 52/165 (31%), Positives = 76/165 (45%), Gaps = 12/165 (7%)
Query: 1817 SSGGKSGSAFLKTLDDRFVIKELSHSELDAFINFSSSYFEYMSQALFHDLPTALAKILGF 1876
SS GKSGS F T DDRF+IK + SE+ + SY++++ Q + F
Sbjct: 450 SSPGKSGSFFYLTQDDRFMIKTVKKSEVKVLLRMLPSYYKHVCQ-------YENTLVTRF 502
Query: 1877 YQIQIRNAATGKSFKMDVIIMENLF-YEKKTSRIFDLKGSMRNRHVEQTGKENEVLLDEN 1935
Y + G+ K I+M NLF E + R FDLKGS R+ + E E+
Sbjct: 503 YGVHCIKPVGGQ--KTRFIVMGNLFCSEYRIQRRFDLKGSSHGRYTSK--PEGEIDETTT 558
Query: 1936 MVEYIYESPIFVREYDKKLLRASLWNDTLFLAKMNVMDYSLVVGV 1980
+ + ++ + L + D FL +MDYSL+VGV
Sbjct: 559 LKDLDLNFAFRLQRNWYQELMTQIKRDCEFLEAERIMDYSLLVGV 603
>Hs14745097 [T] KOG0229 Phosphatidylinositol-4-phosphate 5-kinase
Length = 435
Score = 63.9 bits (154), Expect = 3e-09
Identities = 48/172 (27%), Positives = 81/172 (46%), Gaps = 14/172 (8%)
Query: 1818 SGGKSGSAFLKTLDDRFVIKELSHSELDAFINFSSSYFEYMSQALFHDLPTALAKILGFY 1877
S G SGS F + DD F++K + H E + Y+ ++Q + T L K G Y
Sbjct: 122 SSGASGSLFYVSSDDEFIVKTVRHKEAEFLQKLLPGYYINLNQ----NPRTLLPKFYGLY 177
Query: 1878 QIQIRNAATGKSFKMDVIIMENLFYEKKTSRI-FDLKGSMRNRHVEQTGKENEVLLDENM 1936
+Q GK+ + +++M NL I +DLKGS R Q +E + +++
Sbjct: 178 CVQ----TGGKNIR--IVVMNNLLPRSVKMHIKYDLKGSTYRRRASQKEREKPLPTFKDL 231
Query: 1937 VEYIYESP--IFVREYDKKLLRASLWNDTLFLAKMNVMDYSLVVGVDNQTHS 1986
+++ + P +F+ L +L D L L +MDYSL++ + N H+
Sbjct: 232 -DFLQDIPDGLFLDADVHNALCKTLQRDCLVLQSFKIMDYSLLMSIHNIDHA 282
>At1g21980 [T] KOG0229 Phosphatidylinositol-4-phosphate 5-kinase
Length = 752
Score = 63.5 bits (153), Expect = 3e-09
Identities = 52/165 (31%), Positives = 76/165 (45%), Gaps = 12/165 (7%)
Query: 1817 SSGGKSGSAFLKTLDDRFVIKELSHSELDAFINFSSSYFEYMSQALFHDLPTALAKILGF 1876
SS GKSGS F T DDRF+IK + SE+ + SY++++ Q + + F
Sbjct: 448 SSPGKSGSFFYLTQDDRFMIKTVKKSEVKVLLRMLPSYYKHVCQ-------YENSLVTRF 500
Query: 1877 YQIQIRNAATGKSFKMDVIIMENLF-YEKKTSRIFDLKGSMRNRHVEQTGKENEVLLDEN 1935
Y + G+ K I+M NLF E + R FDLKGS R + E +
Sbjct: 501 YGVHCVKPVGGQ--KTRFIVMGNLFCSEYRIQRRFDLKGSSHGRSTAKPEGEIDETTTLK 558
Query: 1936 MVEYIYESPIFVREYDKKLLRASLWNDTLFLAKMNVMDYSLVVGV 1980
++ + + Y + L + D FL +MDYSL+VGV
Sbjct: 559 DLDLNFSFRLQRNWYQE--LMKQIKRDCEFLEAERIMDYSLLVGV 601
>CE06781 [TU] KOG1818 Membrane trafficking and cell signaling protein HRS
contains VHS and FYVE domains
Length = 765
Score = 63.2 bits (152), Expect = 4e-09
Identities = 26/53 (49%), Positives = 31/53 (58%), Gaps = 1/53 (1%)
Query: 257 ECFNCAKPFTTFRRKHHCRICGQIFCSSCSFL-ITGESFGYSGRMRICGKCYE 308
EC+ C F+ F RKHHCR CGQIFC CS + FG +R+C CYE
Sbjct: 198 ECYRCRSVFSVFTRKHHCRACGQIFCDKCSSRELALPQFGIEKEVRVCETCYE 250
>SPBC25H2.12c [O] KOG0361 Chaperonin complex component TCP-1 eta subunit (CCT7)
Length = 558
Score = 62.4 bits (150), Expect = 7e-09
Identities = 53/217 (24%), Positives = 93/217 (42%), Gaps = 19/217 (8%)
Query: 709 DFKQQHVKIKRLPGGSVLDSMILNGVLYSKGLP---LKTMPRVVMNPRILLIMFPLEYQK 765
D + + IK++PGG++ DS+++ GV + K + P+ NP+IL + LE +
Sbjct: 194 DLNENMIGIKKVPGGAMEDSLLVKGVAFKKTFSYAGFEQQPKFFKNPKILCLDVELELKA 253
Query: 766 HNNH-------VISIESVVAQEKEYLKKLVLRLQSLNPDIILTGTSASGYALQLFQEVGI 818
++ V +++V E + + + + ++L+ A Q F + I
Sbjct: 254 EKDNAEVRVDKVQEYQNIVDAEWRIIFSKLEAIVATGAKVVLSKLPIGDLATQYFADRDI 313
Query: 819 VVQCNVKPQVIERISRFTGCDIVITMDKLSSNIKLGTCERFEVRTYIYGNLSKNYTFITG 878
V + R+ + G I T + LGTC+ FE R I G+ + G
Sbjct: 314 FCAGRVAADDLNRVVQAVGGSIQSTCSNIEEK-HLGTCDTFEER-QIGGD---RFNLFEG 368
Query: 879 CKTQAGITLVLRGNT----SEVLRKVKDVAEFVAYAV 911
C TL+LRG +EV R + D V +A+
Sbjct: 369 CPKAKTCTLILRGGADQFIAEVERSLHDAIMIVKHAL 405
>CE20122 [TU] KOG1786 Lysosomal trafficking regulator LYST and related BEACH
and WD40 repeat proteins
Length = 931
Score = 62.4 bits (150), Expect = 7e-09
Identities = 27/63 (42%), Positives = 39/63 (61%), Gaps = 1/63 (1%)
Query: 247 EYWMKDESAKECFNCAKPFTTFRRKHHCRICGQIFCSSCS-FLITGESFGYSGRMRICGK 305
++W++D + + C +C FT RKHHCR CGQIFCS+CS F S +R+C K
Sbjct: 858 DHWVQDVTRQRCDDCEHKFTLADRKHHCRNCGQIFCSTCSRFESHITRMNISRPVRVCRK 917
Query: 306 CYE 308
C++
Sbjct: 918 CFQ 920
>At3g20050 [O] KOG0360 Chaperonin complex component TCP-1 alpha subunit (CCT1)
Length = 545
Score = 62.4 bits (150), Expect = 7e-09
Identities = 51/248 (20%), Positives = 109/248 (43%), Gaps = 11/248 (4%)
Query: 662 KLHLEALLQQALTDQEIPGEGDWIAIFNKMIGQIQGIPLDARKAGDLDFKQQHVKIKRLP 721
K+ L + +++ + I G+ D+ A N ++ + + + ++ G++ + + + I +
Sbjct: 148 KVPLINCAKTSMSSKLISGDSDFFA--NLVVEAVLSVKMTNQR-GEIKYPIKGINILKAH 204
Query: 722 GGSVLDSMILNGVLYSKGLPLKTMPRVVMNPRILLIMFPLEYQKHN-------NHVISIE 774
G S DS +LNG + G + MP V +I + F L+ K N +E
Sbjct: 205 GQSARDSYLLNGYALNTGRAAQGMPLRVSPAKIACLDFNLQKTKMQLGVQVVVNDPRELE 264
Query: 775 SVVAQEKEYLKKLVLRLQSLNPDIILTGTSASGYALQLFQEVGIVVQCNVKPQVIERISR 834
+ +E + K+ + +L ++ILT AL+ F E G + V+ + + +++
Sbjct: 265 KIRQREADMTKERIEKLLKAGANVILTTKGIDDMALKYFVEAGAIAVRRVRKEDMRHVAK 324
Query: 835 FTGCDIVITMDKLSSNIKLGTCERFEVRTYIYGNLS-KNYTFITGCKTQAGITLVLRGNT 893
TG +V T + + ++ + I G KT + ++L+LRG
Sbjct: 325 ATGATLVTTFADMEGEETFDPAHLGSADEVVEERIADDDVILIKGTKTSSAVSLILRGAN 384
Query: 894 SEVLRKVK 901
+L +++
Sbjct: 385 DYMLDEME 392
>Hs5453607 [O] KOG0361 Chaperonin complex component TCP-1 eta subunit (CCT7)
Length = 543
Score = 62.0 bits (149), Expect = 1e-08
Identities = 68/323 (21%), Positives = 140/323 (43%), Gaps = 33/323 (10%)
Query: 652 DKREELNDVCKLHLEALLQQALTDQEIPGEGDWIAIFNKMIGQIQGIPLDARKAGDLDFK 711
DK E+ + K + AL + ++ Q+ A F KM+ +DA D +
Sbjct: 147 DKVEQRKLLEKCAMTALSSKLISQQK--------AFFAKMV-------VDAVMMLDDLLQ 191
Query: 712 QQHVKIKRLPGGSVLDSMILNGVLYSKGLP---LKTMPRVVMNPRILLIMFPLEYQKHNN 768
+ + IK++ GG++ DS ++ GV + K + P+ NP+I L+ LE + +
Sbjct: 192 LKMIGIKKVQGGALEDSQLVAGVAFKKTFSYAGFEMQPKKYHNPKIALLNVELELKAEKD 251
Query: 769 H-------VISIESVVAQEKEYLKKLVLRLQSLNPDIILTGTSASGYALQLFQEVGIVVQ 821
+ V +++V E L + ++ ++L+ A Q F + +
Sbjct: 252 NAEIRVHTVEDYQAIVDAEWNILYDKLEKIHHSGAKVVLSKLPIGDVATQYFADRDMFCA 311
Query: 822 CNVKPQVIERISRFTGCDIVITMDKLSSNIKLGTCERFEVRTYIYGNLSKNYTFITGCKT 881
V + ++R G I +++ LS+++ LG C+ FE T I G + Y F TGC
Sbjct: 312 GRVPEEDLKRTMMACGGSIQTSVNALSADV-LGRCQVFE-ETQIGG---ERYNFFTGCPK 366
Query: 882 QAGITLVLRGNTSEVLRKV-KDVAEFVAYAVFSMKLESSFFNDNFLQLNIEAY--KHIQL 938
T +LRG + + + + + + + ++K +S +++ + Y + +
Sbjct: 367 AKTCTFILRGGAEQFMEETERSLHDAIMIVRRAIKNDSVVAGGGAIEMELSKYLRDYSRT 426
Query: 939 LKKQNESFTGFFADFIEKFNRRI 961
+ + + G +A +E R++
Sbjct: 427 IPGKQQLLIGAYAKALEIIPRQL 449
>Hs22044271 [TU] KOG1786 Lysosomal trafficking regulator LYST and related BEACH
and WD40 repeat proteins
Length = 1513
Score = 61.6 bits (148), Expect = 1e-08
Identities = 25/62 (40%), Positives = 35/62 (56%), Gaps = 1/62 (1%)
Query: 247 EYWMKDESAKECFNCAKPFTTFRRKHHCRICGQIFCSSCS-FLITGESFGYSGRMRICGK 305
++W+KDE C C+ F+ R+HHCR CGQ+FC CS F + S +R+C
Sbjct: 1436 DHWVKDEGGDSCSGCSVRFSLTERRHHCRNCGQLFCQKCSRFQSEIKRLKISSPVRVCQN 1495
Query: 306 CY 307
CY
Sbjct: 1496 CY 1497
>Hs13376757 [R] KOG1729 FYVE finger containing protein
Length = 310
Score = 61.2 bits (147), Expect = 2e-08
Identities = 26/59 (44%), Positives = 34/59 (57%), Gaps = 1/59 (1%)
Query: 249 WMKDESAKECFNCAKPFTTFRRKHHCRICGQIFCSSCSFLITGESFGYSGRMRICGKCY 307
W+KD+ A C C K F+ RRKHHCR CG IFC++CS Y +R+C C+
Sbjct: 241 WLKDDEATHCRQCEKEFSISRRKHHCRNCGHIFCNTCSSNELALP-SYPKPVRVCDSCH 298
>Hs4758528 [TU] KOG1818 Membrane trafficking and cell signaling protein HRS
contains VHS and FYVE domains
Length = 777
Score = 60.5 bits (145), Expect = 3e-08
Identities = 27/55 (49%), Positives = 30/55 (54%), Gaps = 1/55 (1%)
Query: 255 AKECFNCAKPFTTFRRKHHCRICGQIFCSSCSF-LITGESFGYSGRMRICGKCYE 308
A+EC C F RKHHCR CGQIFC CS T FG +R+C CYE
Sbjct: 163 AEECHRCRVQFGVMTRKHHCRACGQIFCGKCSSKYSTIPKFGIEKEVRVCEPCYE 217
>At2g26420 [T] KOG0229 Phosphatidylinositol-4-phosphate 5-kinase
Length = 705
Score = 60.5 bits (145), Expect = 3e-08
Identities = 53/204 (25%), Positives = 92/204 (44%), Gaps = 36/204 (17%)
Query: 1785 IFFFEQFDAFRKKCGCGEENFIQSLSRCIKWDSSGGKSGSAFLKTLDDRFVIKELSHSEL 1844
+F +Q D CG + ++ +S GKSGSAF T D+R++IK + SE+
Sbjct: 400 LFAIDQADYMLAICG----------NESLREFASPGKSGSAFYLTQDERYMIKTMKKSEI 449
Query: 1845 DAFINFSSSYFEYMSQALFHDLPTALAKILGFYQIQIRNAATGKSFKMDVIIMENLF-YE 1903
+ +Y+E++S+ + + F+ + G+ K I+M NLF E
Sbjct: 450 KVLLKMLPNYYEHVSK-------YKNSLVTKFFGVHCVKPVGGQ--KTRFIVMGNLFCSE 500
Query: 1904 KKTSRIFDLKGSMRNRHVEQTGKE--NEVLLDENMVEYIYE-----SPIFVREYDKKLLR 1956
+ + FDLKGS R +++ E L + ++Y++ F+ + D
Sbjct: 501 YRIHKRFDLKGSSHGRTIDKDEGEIDETTTLKDLDLKYVFRLETSWFQAFINQIDL---- 556
Query: 1957 ASLWNDTLFLAKMNVMDYSLVVGV 1980
D FL +MDYSL++G+
Sbjct: 557 -----DCEFLEAERIMDYSLLIGL 575
>At3g07960 [T] KOG0229 Phosphatidylinositol-4-phosphate 5-kinase
Length = 715
Score = 59.7 bits (143), Expect = 5e-08
Identities = 51/168 (30%), Positives = 79/168 (46%), Gaps = 16/168 (9%)
Query: 1817 SSGGKSGSAFLKTLDDRFVIKELSHSELDAFINFSSSYFEYMSQALFHDLPTALAKILGF 1876
SS GKSGS F T DDR++IK + +E I +Y+ ++ T + K G
Sbjct: 423 SSPGKSGSFFYLTNDDRYMIKTMKKAETKVLIRMLPAYYNHVRAC----ENTLVTKFFGL 478
Query: 1877 YQIQIRNAATGKSFKMDVIIMENLFYE-KKTSRIFDLKGSMRNRHVEQTGKE---NEVLL 1932
+ +++ A K+ +IM NLF R FDLKGS R + E N L
Sbjct: 479 HCVKLTGTA---QKKVRFVIMGNLFCTGHSIHRRFDLKGSSHGRLTTKPESEIDPNTTLK 535
Query: 1933 DENMVEYIYESPIFVREYDKKLLRASLWNDTLFLAKMNVMDYSLVVGV 1980
D ++ + +E+ +++ R D FL + +MDYSL+VG+
Sbjct: 536 DLDLNFAFRLQKNWFQEFCRQVDR-----DCEFLEQERIMDYSLLVGL 578
>At1g20110 [R] KOG1729 FYVE finger containing protein
Length = 613
Score = 59.7 bits (143), Expect = 5e-08
Identities = 23/64 (35%), Positives = 38/64 (58%), Gaps = 5/64 (7%)
Query: 246 KEYWMKDESAKECFNCAKPFTTFRRKHHCRICGQIFCSSCS---FLITGESFGYSGRMRI 302
K++W+ DE+ +C +C F F R+HHCR CG +FC C+ +T E + ++R+
Sbjct: 449 KDHWVPDEAVSKCTSCGSDFGAFIRRHHCRNCGDVFCDKCTQGRIALTAED--NAPQVRV 506
Query: 303 CGKC 306
C +C
Sbjct: 507 CDRC 510
>YIL142w [O] KOG0363 Chaperonin complex component TCP-1 beta subunit (CCT2)
Length = 527
Score = 59.3 bits (142), Expect = 6e-08
Identities = 47/193 (24%), Positives = 88/193 (45%), Gaps = 14/193 (7%)
Query: 713 QHVKIKRLPGGSVLDSMILNGVLYSKGLPLKTMPRVVMNPRILLIMFPLEYQKHN----- 767
+H++I ++ GG + DS + G + +K P+ + N +IL+ L+ K
Sbjct: 191 EHIQIIKILGGKLSDSFLDEGFILAKKFG-NNQPKRIENAKILIANTTLDTDKVKIFGTK 249
Query: 768 ---NHVISIESVVAQEKEYLKKLVLRLQSLNPDIILTGTSASGYALQLFQEVGIVVQCNV 824
+ + + E+E +K + ++ + + Y QLF ++GI +
Sbjct: 250 FKVDSTAKLAQLEKAEREKMKNKIAKISKFGINTFINRQLIYDYPEQLFTDLGINSIEHA 309
Query: 825 KPQVIERISRFTGCDIVITMDKLSSNIKLGTCERFEVRTYIYGNLSKNYTFITGCKTQAG 884
+ +ER++ TG ++V T D+ S KLG C+ E + G + + +GCK
Sbjct: 310 DFEGVERLALVTGGEVVSTFDE-PSKCKLGECDVIE--EIMLGE--QPFLKFSGCKAGEA 364
Query: 885 ITLVLRGNTSEVL 897
T+VLRG T + L
Sbjct: 365 CTIVLRGATDQTL 377
>YGL023c [R] KOG1729 FYVE finger containing protein
Length = 635
Score = 59.3 bits (142), Expect = 6e-08
Identities = 31/107 (28%), Positives = 47/107 (42%), Gaps = 13/107 (12%)
Query: 245 SKEYWMKDESAKECFNCAKPFTTFRRKHHCRICGQIFC-----------SSCSFLITGE- 292
+K++W+ D C C KPFT + RKHHCR CG IFC S +F++ E
Sbjct: 445 TKDHWIPDSKRNSCRYCHKPFTLWERKHHCRHCGDIFCQDHLRHWLYLDSQANFIMINEL 504
Query: 293 -SFGYSGRMRICGKCYEHSMNYXXXXXXXXXXXIIHDQVSSRNIDDD 338
+ G +G +C C + + Y D ++ +DD
Sbjct: 505 NNGGINGGGTLCKICDDCLVEYENLSTTNHNANTNEDNINVEEGEDD 551
>SPBC36B7.05c [R] KOG1729 FYVE finger containing protein
Length = 279
Score = 58.5 bits (140), Expect = 1e-07
Identities = 20/37 (54%), Positives = 27/37 (72%)
Query: 249 WMKDESAKECFNCAKPFTTFRRKHHCRICGQIFCSSC 285
W D+ + +C NC PFT FRR+HHCR CG++FC +C
Sbjct: 24 WQLDDESAQCNNCGGPFTWFRRRHHCRWCGKLFCYNC 60
>YDR313c [R] KOG1729 FYVE finger containing protein
Length = 286
Score = 58.2 bits (139), Expect = 1e-07
Identities = 36/121 (29%), Positives = 49/121 (39%), Gaps = 13/121 (10%)
Query: 249 WMKDESAKECFNCAKPFTTFRRKHHCRICGQIFCSSCS------------FLITGESFGY 296
W DE A CF C F+ R+HHCR CG+IFCSSC+ L S
Sbjct: 14 WQADEEAHSCFQCKTNFSFLVRRHHCRCCGRIFCSSCTENFVNYNKKRVHALQKKNSDVE 73
Query: 297 SGRMRICGKCYEHSMNY-XXXXXXXXXXXIIHDQVSSRNIDDDAPSLNNDDIQSILTNVD 355
S R C +CY++ ++ + V + AP N D+ IL +
Sbjct: 74 SPPYRTCNECYDNLLHLNLLVSSTNRDVRLSQTSVPPNALALSAPDSNTDEDAEILEDSV 133
Query: 356 D 356
D
Sbjct: 134 D 134
>Hs6552339 [V] KOG1841 Smad anchor for receptor activation
Length = 1210
Score = 57.8 bits (138), Expect = 2e-07
Identities = 24/64 (37%), Positives = 33/64 (51%)
Query: 249 WMKDESAKECFNCAKPFTTFRRKHHCRICGQIFCSSCSFLITGESFGYSGRMRICGKCYE 308
W+ D A C C FT +R+HHCR CG++FC+SC L + R+C C+
Sbjct: 696 WVPDSQAPNCMKCEARFTFTKRRHHCRACGKVFCASCCSLKCKLLYMDRKEARVCVICHS 755
Query: 309 HSMN 312
MN
Sbjct: 756 VLMN 759
>Hs6552337 [V] KOG1841 Smad anchor for receptor activation
Length = 762
Score = 57.8 bits (138), Expect = 2e-07
Identities = 24/64 (37%), Positives = 33/64 (51%)
Query: 249 WMKDESAKECFNCAKPFTTFRRKHHCRICGQIFCSSCSFLITGESFGYSGRMRICGKCYE 308
W+ D A C C FT +R+HHCR CG++FC+SC L + R+C C+
Sbjct: 696 WVPDSQAPNCMKCEARFTFTKRRHHCRACGKVFCASCCSLKCKLLYMDRKEARVCVICHS 755
Query: 309 HSMN 312
MN
Sbjct: 756 VLMN 759
>Hs4759060 [V] KOG1841 Smad anchor for receptor activation
Length = 1323
Score = 57.8 bits (138), Expect = 2e-07
Identities = 24/64 (37%), Positives = 33/64 (51%)
Query: 249 WMKDESAKECFNCAKPFTTFRRKHHCRICGQIFCSSCSFLITGESFGYSGRMRICGKCYE 308
W+ D A C C FT +R+HHCR CG++FC+SC L + R+C C+
Sbjct: 594 WVPDSQAPNCMKCEARFTFTKRRHHCRACGKVFCASCCSLKCKLLYMDRKEARVCVICHS 653
Query: 309 HSMN 312
MN
Sbjct: 654 VLMN 657
>CE01234 [O] KOG0359 Chaperonin complex component TCP-1 zeta subunit (CCT6)
Length = 539
Score = 57.8 bits (138), Expect = 2e-07
Identities = 82/363 (22%), Positives = 147/363 (39%), Gaps = 54/363 (14%)
Query: 653 KREELNDVCKLHLEALLQQALTDQEIPGEGDWIAIFNKMIGQIQGIPLDARKAGDLDFKQ 712
+R+ L +VC+ L L Q L D I ++ + I D + DL
Sbjct: 144 ERDLLVEVCRTALRTKLHQKLADH----------ITECVVDAVLAIRRDGEEP-DLHM-- 190
Query: 713 QHVKIKRLPGGSVLDSMILNGVLYSKGLPLKTMPRVVMNPRILLIMFPLEYQKHNNH--- 769
V+ + S +D+ ++ G++ G MPR V + IL LEY+K +
Sbjct: 191 --VEKMEMHHDSDMDTTLVRGLVLDHGARHPDMPRHVKDAYILTCNVSLEYEKTEVNSGL 248
Query: 770 ----VISIESVVAQEKEYLKKLVLRLQSL-------NPD------IILTGTSASGYALQL 812
E+++A E+E++ + V ++ L +PD +++ +L L
Sbjct: 249 FYKTAKEREALLAAEREFITRRVHKIIELKKKVIDNSPDGKNKGFVVINQKGIDPPSLDL 308
Query: 813 FQEVGIVVQCNVKPQVIERISRFTGCDIVITMDKLSSNIKLGTCERFEVRTYIYGNLSKN 872
GI+ K + +ER+ G + V ++D L+ LG + Y + +
Sbjct: 309 LASEGILALRRAKRRNMERLQLAVGGEAVNSVDDLTPE-DLG----WAGLVYEHSLGEEK 363
Query: 873 YTFITGCKTQAGITLVLRGNTSEVLRKVKDVAEFVAYAVFSMKLESSFFNDNFLQLNIEA 932
YTFI C+ +TL+++G + ++KD AVF+ ++ + I A
Sbjct: 364 YTFIEECRAPKSVTLLIKGPNKHTITQIKDAIHDGLRAVFNTIVDKAVL-PGAAAFEIAA 422
Query: 933 YKHIQLLKKQNESFTGFFADFIEKFNRRILSVSPIVEFPVPYLLQKARDVEQQLI----E 988
Y +LKK E+ G E F + +L + P + D ++ L+ E
Sbjct: 423 Y---VMLKKDVENLKGRAKLGAEAFAQALLVI------PKTLAVNGGYDAQETLVKLIEE 473
Query: 989 KTA 991
KTA
Sbjct: 474 KTA 476
>7299092 [O] KOG0361 Chaperonin complex component TCP-1 eta subunit (CCT7)
Length = 501
Score = 57.8 bits (138), Expect = 2e-07
Identities = 45/197 (22%), Positives = 86/197 (42%), Gaps = 15/197 (7%)
Query: 715 VKIKRLPGGSVLDSMILNGVLYSKGLP---LKTMPRVVMNPRILLIMFPLEYQKHN---- 767
+ IK++ GGS+ +S +++GV + K + P+ N +I L+ LE +
Sbjct: 151 IGIKKVTGGSLEESQLVSGVAFKKTFSYAGFEMAPKSYDNCKIALLNIELELKAERDNAE 210
Query: 768 ---NHVISIESVVAQEKEYLKKLVLRLQSLNPDIILTGTSASGYALQLFQEVGIVVQCNV 824
++V + VV E + L + ++ +++L+ A Q F + I V
Sbjct: 211 IRVDNVKEYQKVVDAEWQILYNKLAKIHESGANVVLSKLPIGDVATQYFADRDIFCAGRV 270
Query: 825 KPQVIERISRFTGCDIVITMDKLSSNIKLGTCERFEVRTYIYGNLSKNYTFITGCKTQAG 884
+ ++R + G ++ T + + N+ LG CE FE R + + GC
Sbjct: 271 PEEDLKRTMKACGGAVMTTANDIKPNV-LGLCEHFEERQV----GGERFNLFQGCPNAKT 325
Query: 885 ITLVLRGNTSEVLRKVK 901
TL+LRG + L + +
Sbjct: 326 STLILRGGAEQFLEETE 342
>7290174 [R] KOG1729 FYVE finger containing protein
Length = 316
Score = 57.8 bits (138), Expect = 2e-07
Identities = 30/102 (29%), Positives = 46/102 (44%), Gaps = 7/102 (6%)
Query: 249 WMKDESAKECFNCAKP-FTTFRRKHHCRICGQIFCSSCS---FLITGESFGYSGRMRICG 304
W+ D A C +C K FT +R+HHCR CG + C+ CS FL+ +S + +R+C
Sbjct: 149 WVPDTDASVCMHCKKTQFTFIQRRHHCRNCGAVVCAGCSAKKFLLPQQS---TKALRVCD 205
Query: 305 KCYEHSMNYXXXXXXXXXXXIIHDQVSSRNIDDDAPSLNNDD 346
CYE + S ++ A +ND+
Sbjct: 206 ACYERLKHVPSSLGSGEDSAAATGAASGNKLNTTAGDSSNDE 247
>ECU06g0510 [O] KOG0359 Chaperonin complex component TCP-1 zeta subunit (CCT6)
Length = 510
Score = 57.4 bits (137), Expect = 2e-07
Identities = 46/208 (22%), Positives = 93/208 (44%), Gaps = 21/208 (10%)
Query: 710 FKQQHVKIKRLPGGSVLDSMILNGVLYSKGLPLKTMPRVVMNPRILLIMFPLEYQKHNNH 769
F V++ ++ G V ++M ++G++ G MP + + +L+ LEY+K +
Sbjct: 180 FDMNMVEVIKMQEGDVSETMYVDGLVLDHGGRHYAMPTSLEDVCVLITNMSLEYEKPEIN 239
Query: 770 VISIESVVAQEKEYL---KKLVLRLQSLNPD-------------IILTGTSASGYALQLF 813
S Q E ++ +L+ + I++T Y+L++F
Sbjct: 240 AEFCYSTAGQRDELAVREREFILQRSRAIAEFGRRIKESHGKNLIVVTEKGIDPYSLEVF 299
Query: 814 QEVGIVVQCNVKPQVIERISRFTGCDIVITMDKLSSNIKLGTCERFEVRTYIYGNLSKNY 873
E GI+ K + +ER+ + G ++ + +LS LG C+R VR + +
Sbjct: 300 AESGILALRRAKRRNLERLVKMCGGSLITQVGQLSEK-ALGYCQRVSVRKI----GDEMF 354
Query: 874 TFITGCKTQAGITLVLRGNTSEVLRKVK 901
TFI G + T+++RGN+ + +++
Sbjct: 355 TFIEGTPFKGSCTILIRGNSQHEMSRME 382
>CE27279 [T] KOG0229 Phosphatidylinositol-4-phosphate 5-kinase
Length = 401
Score = 57.4 bits (137), Expect = 2e-07
Identities = 49/168 (29%), Positives = 82/168 (48%), Gaps = 14/168 (8%)
Query: 1816 DSSGGKSGSAFLKTLDDRFVIKELSHSELDAFINFSSSYFEYMSQALFHDLPTALAKILG 1875
D S S F + D +FVIK + + + +Y +Y+ + T L + LG
Sbjct: 121 DGSAKDSTPRFFISYDKKFVIKSMDSEAVAELHSVLRNYHQYVVEK---QGKTLLPQYLG 177
Query: 1876 FYQIQIRNAATGKSFKMDVIIMENLFYEKKTSRI-FDLKGSMRNRHV--EQTGKENEVLL 1932
Y++ I + T +I+M N+F K FDLKGS +R ++ K+ L
Sbjct: 178 LYRLTIEGSETY------LIVMRNVFGRKYGVHTKFDLKGSTVSRAASDKEKAKDLPTLK 231
Query: 1933 DENMVEYIYESPIFVREYDKKLLRASLWNDTLFLAKMNVMDYSLVVGV 1980
D + +E ++ + + KLL L +DT +L +M++MDYSL+VG+
Sbjct: 232 DNDFLEQNWK--LNLPPEAGKLLIEMLTSDTEWLTRMHLMDYSLLVGI 277
>SPAC19G12.14 [T] KOG0229 Phosphatidylinositol-4-phosphate 5-kinase
Length = 742
Score = 57.0 bits (136), Expect = 3e-07
Identities = 47/181 (25%), Positives = 85/181 (45%), Gaps = 15/181 (8%)
Query: 1818 SGGKSGSAFLKTLDDRFVIKELSHSELDAFINFSSSYFEYMSQALFHDLPTALAKILGFY 1877
S GKSGS F + D RF+IK + HSE Y+E++ ++ T +++ G +
Sbjct: 360 SPGKSGSFFYFSRDYRFIIKTIHHSEHKFLREILYDYYEHVK----NNPNTLISQFYGLH 415
Query: 1878 QIQIRNAATGKSFKMDVIIMENLF-YEKKTSRIFDLKGSMRNRHVEQTGKENEVLLDENM 1936
++++ K+ ++M NLF + + FDLKGS R +++ +
Sbjct: 416 RVKLPFGR-----KIHFVVMNNLFPPHRDIHQTFDLKGSTLGRELDENQPCQSPMCTMKD 470
Query: 1937 VEYIYES-PIFVREYDKKLLRASLWNDTLFLAKMNVMDYSLVVGVDNQTHSLTVGIIDCI 1995
+I + + +++ + D L+ + +MDYSL+VG+ H L+ G D I
Sbjct: 471 TNWIRRNMHLQFGPLKRQIFLTQVKADIDMLSSLGIMDYSLLVGI----HDLSRGNRDKI 526
Query: 1996 R 1996
R
Sbjct: 527 R 527
>Hs10863893 [IU] KOG4471 Phosphatidylinositol 3-phosphate 3-phosphatase
myotubularin MTM1
Length = 1195
Score = 57.0 bits (136), Expect = 3e-07
Identities = 23/62 (37%), Positives = 32/62 (51%), Gaps = 1/62 (1%)
Query: 249 WMKDESAKECFNCAKPFTTFRRKHHCRICGQIFCSSCSFL-ITGESFGYSGRMRICGKCY 307
W+ D A C+NC F +R+HHCR CG +FC+ C L + + +C CY
Sbjct: 1111 WVPDHMASHCYNCDCEFWLAKRRHHCRNCGNVFCAGCCHLKLPIPDQQLYDPVLVCNSCY 1170
Query: 308 EH 309
EH
Sbjct: 1171 EH 1172
>YDR208w [T] KOG0229 Phosphatidylinositol-4-phosphate 5-kinase
Length = 779
Score = 56.6 bits (135), Expect = 4e-07
Identities = 58/205 (28%), Positives = 92/205 (44%), Gaps = 20/205 (9%)
Query: 1789 EQFDAFRKKCGCGEENFIQSLSR--CIKWDSSGGKSGSAFLKTLDDRFVIKELSHSELDA 1846
E F R G +++ SL+ + +S GKSGS F + D +++IK + HSE
Sbjct: 446 EVFRELRALFGLDPADYLVSLTSKYILSELNSPGKSGSFFYYSRDYKYIIKTIHHSEHIH 505
Query: 1847 FINFSSSYFEYMSQALFHDLP-TALAKILGFYQIQIRNAATGK--SFKMDVIIMENLFYE 1903
Y+ ++ D P T + + G +++++ + K K+ ++M NLF
Sbjct: 506 LRKHIQEYYNHV-----RDNPNTLICQFYGLHRVKMPISFQNKIKHRKIYFLVMNNLFPP 560
Query: 1904 KKTSRI-FDLKGSMRNRHV----EQTGKENE---VLLDENMVEYIYESPIFVREYDKKLL 1955
I +DLKGS R E+ K+ V+ D N +E I KK
Sbjct: 561 HLDIHITYDLKGSTWGRFTNLDKERLAKDRSYRPVMKDLNWLEE--GQKIKFGPLKKKTF 618
Query: 1956 RASLWNDTLFLAKMNVMDYSLVVGV 1980
L D LAK+N MDYSL++G+
Sbjct: 619 LTQLKKDVELLAKLNTMDYSLLIGI 643
>CE19557 [R] KOG1819 FYVE finger-containing proteins
Length = 658
Score = 56.6 bits (135), Expect = 4e-07
Identities = 20/38 (52%), Positives = 26/38 (67%)
Query: 249 WMKDESAKECFNCAKPFTTFRRKHHCRICGQIFCSSCS 286
W+ DE ++C C+ PF RR+HHCR CG+IFC CS
Sbjct: 563 WVPDEDCEQCTACSMPFNFVRRRHHCRNCGRIFCHKCS 600
>At3g43230 [S] KOG1843 Uncharacterized conserved protein
Length = 485
Score = 56.2 bits (134), Expect = 5e-07
Identities = 25/63 (39%), Positives = 31/63 (48%), Gaps = 3/63 (4%)
Query: 249 WMKDESAKECFNCAKPFTTFR-RKHHCRICGQIFCSSCS--FLITGESFGYSGRMRICGK 305
W+ D A C C+ PFT +HHCR CG IFC +CS + F R+C
Sbjct: 172 WLPDSLASTCMQCSTPFTAITCGRHHCRFCGGIFCRNCSKGRCLMPSRFRERNPQRVCDS 231
Query: 306 CYE 308
CYE
Sbjct: 232 CYE 234
>Hs14784247 [R] KOG1811 Predicted Zn2+-binding protein contains FYVE domain
Length = 989
Score = 55.8 bits (133), Expect = 7e-07
Identities = 24/66 (36%), Positives = 35/66 (52%), Gaps = 1/66 (1%)
Query: 245 SKEYWMKDESAKECFNCAKP-FTTFRRKHHCRICGQIFCSSCSFLITGESFGYSGRMRIC 303
++ W+ DE+ C C + FT F R+HHCR CG++ CSSCS R+C
Sbjct: 255 ARHQWVPDETESICMVCCREHFTMFNRRHHCRRCGRLVCSSCSTKKMVVEGCRENPARVC 314
Query: 304 GKCYEH 309
+CY +
Sbjct: 315 DQCYSY 320
>7303510 [O] KOG0357 Chaperonin complex component TCP-1 epsilon subunit
(CCT5)
Length = 542
Score = 55.8 bits (133), Expect = 7e-07
Identities = 58/226 (25%), Positives = 97/226 (42%), Gaps = 14/226 (6%)
Query: 687 IFNKMIGQIQGIPLDA-RKAGDLDFKQQH---VKIKRLPGGSVLDSMILNGVLYSKGLPL 742
I NK Q+ + +DA D++ K + +KI+ GG + DSM++ GV+ K L
Sbjct: 178 IVNKCHRQMAEMAVDAVLNVADIEKKDVNFELIKIETKVGGRMEDSMLVKGVIVDKTLSH 237
Query: 743 KTMPRVVMNPRILLIMFPLE----YQKHNNHVISIESVVA---QEKEYLKKLVLRLQSLN 795
MP+ + N ++ ++ P E KH V S E A E+E ++V +++
Sbjct: 238 SQMPKELRNVKLAILTCPFEPPKPKTKHKLDVTSAEDYRALREYEQEKFTQMVKQVKDAG 297
Query: 796 PDIILTGTSASGYALQLFQEVGIVVQCNVKPQVIERISRFTGCDIVITMDKLSSNIKLGT 855
+ + A L + + V IE I+ TG IV ++L+ KLG
Sbjct: 298 ATLAICQWGFDDEANHLLLQQELPAVRWVGGPEIELIAIATGGRIVPRFEELTPE-KLGV 356
Query: 856 CERFEVRTYIYGNLSKNYTFITGCKTQAGITLVLRGNTSEVLRKVK 901
VR +G I CK +T+ LRG + ++ + K
Sbjct: 357 AGL--VREMAFGTSKDKMLVIEECKNSKAVTIFLRGGNAMIIAEAK 400
>Hs20543659 [TU] KOG1818 Membrane trafficking and cell signaling protein HRS
contains VHS and FYVE domains
Length = 777
Score = 55.5 bits (132), Expect = 9e-07
Identities = 25/60 (41%), Positives = 30/60 (49%), Gaps = 1/60 (1%)
Query: 248 YWMKDESAKECFNCAKPFTTFRRKHHCRICGQIFCSSCSF-LITGESFGYSGRMRICGKC 306
YW+ D C NC K F+ KHHCR CGQ FC CS S G+ +R+C C
Sbjct: 711 YWVPDHEILHCHNCRKEFSIKLSKHHCRACGQGFCDECSHDRRAVPSRGWDHPVRVCFNC 770
>SPAC1420.02c [O] KOG0357 Chaperonin complex component TCP-1 epsilon subunit
(CCT5)
Length = 546
Score = 55.1 bits (131), Expect = 1e-06
Identities = 50/202 (24%), Positives = 91/202 (44%), Gaps = 12/202 (5%)
Query: 707 DLDFKQQHVKIKRLPGGSVLDSMILNGVLYSKGLPLKTMPRVVMNPRILLIMFPLE---- 762
D+DF+ +K+ GGSV D+ ++ GV+ K + MP + N +I ++ P E
Sbjct: 205 DVDFEL--IKVDGKVGGSVDDTKLVKGVVVDKDMSHPQMPHRIENAKIAILTCPFEPPKP 262
Query: 763 YQKHNNHVISI---ESVVAQEKEYLKKLVLRLQSLNPDIILTGTSASGYALQLFQEVGIV 819
KH + S+ E++ A EKE ++++ ++ ++++ A L + +
Sbjct: 263 KTKHKLDITSVSEFEALQAYEKEKFQEMIKHVKDAGANLVICQWGFDDEANHLLLQNNLP 322
Query: 820 VQCNVKPQVIERISRFTGCDIVITMDKLSSNIKLGTCERFEVRTYIYGNLSKNYTFITGC 879
V IE I+ T IV + LSS+ KLG+ VR +G I C
Sbjct: 323 AVRWVGGPEIELIAIATNGRIVPRFEDLSSD-KLGSAG--IVREVSFGTTRDKILVIEKC 379
Query: 880 KTQAGITLVLRGNTSEVLRKVK 901
+T+ +RG+ ++ + K
Sbjct: 380 ANSRAVTVFVRGSNKMIVDEAK 401
>Hs7662048 [V] KOG1841 Smad anchor for receptor activation
Length = 1539
Score = 55.1 bits (131), Expect = 1e-06
Identities = 23/60 (38%), Positives = 30/60 (49%), Gaps = 1/60 (1%)
Query: 249 WMKDESAKECFNCAKPFTTFRRKHHCRICGQIFCSSCSFLITGESFGYSGRMRICGKCYE 308
W+ D A C NC FT +R+HHCR CG++FC C + R+C CYE
Sbjct: 744 WVPDSEAPNCMNCQVKFTFTKRRHHCRACGKVFCGVCCNRKCKLQY-LEKEARVCVVCYE 802
>Hs13470092 [R] KOG1729 FYVE finger containing protein
Length = 1478
Score = 54.7 bits (130), Expect = 2e-06
Identities = 23/64 (35%), Positives = 34/64 (52%), Gaps = 1/64 (1%)
Query: 245 SKEYWMKDESAKECFNCAKPFTTFRRKHHCRICGQIFCSSCSFLITGESFGYSGRMRICG 304
++E W+ D A C +C + F+ R+HHCRICG+IFC C G + R C
Sbjct: 1166 AEERWLGDTEANHCLDCKREFSWMVRRHHCRICGRIFCYYCCNNYVLSKHG-GKKERCCR 1224
Query: 305 KCYE 308
C++
Sbjct: 1225 ACFQ 1228
>SPAC19A8.05c [TU] KOG1818 Membrane trafficking and cell signaling protein HRS
contains VHS and FYVE domains
Length = 610
Score = 54.3 bits (129), Expect = 2e-06
Identities = 22/51 (43%), Positives = 29/51 (56%), Gaps = 1/51 (1%)
Query: 258 CFNCAKPFTTFRRKHHCRICGQIFCSSCSF-LITGESFGYSGRMRICGKCY 307
C C PFT RKHHCR CG +FC+ CS ++ G + +R+C CY
Sbjct: 176 CLRCRTPFTFTNRKHHCRNCGGVFCNQCSSKTLSLPHLGINQPVRVCDSCY 226
>CE28255 [O] KOG0361 Chaperonin complex component TCP-1 eta subunit (CCT7)
Length = 535
Score = 53.9 bits (128), Expect = 3e-06
Identities = 44/212 (20%), Positives = 90/212 (41%), Gaps = 15/212 (7%)
Query: 700 LDARKAGDLDFKQQHVKIKRLPGGSVLDSMILNGVLYSKGLP---LKTMPRVVMNPRILL 756
+DA D + IK++ GG++ +S ++ GV + K + P+ N ++ L
Sbjct: 178 VDAVNTLDAHLPLNMIGIKKVNGGNLHESRLIKGVAFQKAFSYAGFEMQPKKYSNVKVAL 237
Query: 757 IMFPLEY--QKHN-----NHVISIESVVAQEKEYLKKLVLRLQSLNPDIILTGTSASGYA 809
+ LE +K N +V ++VV E L + ++ +++L+ A
Sbjct: 238 LNIELELKAEKENAEMRLTNVSDFQAVVDAEWNILYDKLQKIHDSGANVVLSKLPIGDVA 297
Query: 810 LQLFQEVGIVVQCNVKPQVIERISRFTGCDIVITMDKLSSNIKLGTCERFEVRTYIYGNL 869
Q F + + + ++R+ G ++ T+ ++ ++ LG C +F Y
Sbjct: 298 TQWFADRDMFCAGRIPQDDLDRLMSACGGSVLTTVSQIDDSV-LGKCGKF----YEQQVG 352
Query: 870 SKNYTFITGCKTQAGITLVLRGNTSEVLRKVK 901
S+ Y F C TL+LRG + + + +
Sbjct: 353 SERYNFFEDCSKAQACTLLLRGGAEQFIAETE 384
>Hs8922921 [R] KOG1729 FYVE finger containing protein
Length = 432
Score = 53.5 bits (127), Expect = 3e-06
Identities = 22/60 (36%), Positives = 31/60 (51%)
Query: 249 WMKDESAKECFNCAKPFTTFRRKHHCRICGQIFCSSCSFLITGESFGYSGRMRICGKCYE 308
W+ D A C C FT R+HHCR CG+I C +CS G + + R+C C++
Sbjct: 221 WIPDTRATMCMICTSEFTLTWRRHHCRACGKIVCQACSSNKYGLDYLKNQPARVCEHCFQ 280
>Hs13375827 [R] KOG1729 FYVE finger containing protein
Length = 249
Score = 53.5 bits (127), Expect = 3e-06
Identities = 27/64 (42%), Positives = 34/64 (52%), Gaps = 7/64 (10%)
Query: 249 WMKDESAKECFNCAKP-FTTFRRKHHCRICGQIFCSSCS---FLITGESFGYSGRMRICG 304
W+ D A C C K FT R+HHCR CG + C CS FL+ +S S +RIC
Sbjct: 149 WVPDSEATVCMRCQKAKFTPVNRRHHCRKCGFVVCGPCSEKRFLLPSQS---SKPVRICD 205
Query: 305 KCYE 308
CY+
Sbjct: 206 FCYD 209
>Hs10835109 [IU] KOG4471 Phosphatidylinositol 3-phosphate 3-phosphatase
myotubularin MTM1
Length = 1198
Score = 53.1 bits (126), Expect = 4e-06
Identities = 24/60 (40%), Positives = 30/60 (50%), Gaps = 1/60 (1%)
Query: 249 WMKDESAKECFNCAKPFTTFRRKHHCRICGQIFCSS-CSFLITGESFGYSGRMRICGKCY 307
W+ D A C+ C F RKHHCR CG +FCSS C+ + S R+C CY
Sbjct: 1116 WLPDHLAAHCYACDSAFWLASRKHHCRNCGNVFCSSCCNQKVPVPSQQLFEPSRVCKSCY 1175
>7301558_1 [T] KOG4381 RUN domain-containing protein
Length = 951
Score = 53.1 bits (126), Expect = 4e-06
Identities = 20/38 (52%), Positives = 23/38 (59%)
Query: 249 WMKDESAKECFNCAKPFTTFRRKHHCRICGQIFCSSCS 286
W D A C C + F RRKHHCR CG+IFC +CS
Sbjct: 860 WAPDSIATHCTACEREFNLTRRKHHCRSCGEIFCKACS 897
>Hs16159222 [O] KOG0357 Chaperonin complex component TCP-1 epsilon subunit
(CCT5)
Length = 541
Score = 52.8 bits (125), Expect = 6e-06
Identities = 48/202 (23%), Positives = 88/202 (42%), Gaps = 12/202 (5%)
Query: 707 DLDFKQQHVKIKRLPGGSVLDSMILNGVLYSKGLPLKTMPRVVMNPRILLIMFPLE---- 762
D+DF+ +K++ GG + D+ ++ GV+ K MP+ V + +I ++ P E
Sbjct: 203 DVDFEL--IKVEGKVGGRLEDTKLIKGVIVDKDFSHPQMPKKVEDAKIAILTCPFEPPKP 260
Query: 763 YQKHNNHVISIESVVA---QEKEYLKKLVLRLQSLNPDIILTGTSASGYALQLFQEVGIV 819
KH V S+E A EKE ++++ +++ ++ + A L + +
Sbjct: 261 KTKHKLDVTSVEDYKALQKYEKEKFEEMIQQIKETGANLAICQWGFDDEANHLLLQNNLP 320
Query: 820 VQCNVKPQVIERISRFTGCDIVITMDKLSSNIKLGTCERFEVRTYIYGNLSKNYTFITGC 879
V IE I+ TG IV +L++ KLG V+ +G I C
Sbjct: 321 AVRWVGGPEIELIAIATGGRIVPRFSELTAE-KLGFAGL--VQEISFGTTKDKMLVIEQC 377
Query: 880 KTQAGITLVLRGNTSEVLRKVK 901
K +T+ +RG ++ + K
Sbjct: 378 KNSRAVTIFIRGGNKMIIEEAK 399
>7297349 [R] KOG1842 FYVE finger-containing protein
Length = 505
Score = 52.4 bits (124), Expect = 8e-06
Identities = 20/38 (52%), Positives = 25/38 (65%)
Query: 249 WMKDESAKECFNCAKPFTTFRRKHHCRICGQIFCSSCS 286
W+ S K C +CAK F RR+HHCR+CG I C+ CS
Sbjct: 177 WLDGSSVKLCPSCAKSFHIARRQHHCRLCGGIMCNDCS 214
>7291295 [V] KOG1841 Smad anchor for receptor activation
Length = 1291
Score = 52.4 bits (124), Expect = 8e-06
Identities = 17/37 (45%), Positives = 24/37 (63%)
Query: 249 WMKDESAKECFNCAKPFTTFRRKHHCRICGQIFCSSC 285
W+ D A +C C + FT +R+HHCR CG++ CS C
Sbjct: 528 WVPDNMAGQCMQCQQKFTMIKRRHHCRACGKVLCSVC 564
>Hs21245128 [T] KOG4424 Predicted Rho/Rac guanine nucleotide exchange
factor/faciogenital dysplasia protein 3
Length = 766
Score = 52.0 bits (123), Expect = 1e-05
Identities = 20/61 (32%), Positives = 29/61 (46%), Gaps = 1/61 (1%)
Query: 249 WMKDESAKECFNCAKPFTTF-RRKHHCRICGQIFCSSCSFLITGESFGYSGRMRICGKCY 307
W++D C C +PF RR+HHCR CG + C CS + ++C CY
Sbjct: 556 WIRDNEVTMCMKCKEPFNALTRRRHHCRACGYVVCWKCSDYKAQLEYDGGKLSKVCKDCY 615
Query: 308 E 308
+
Sbjct: 616 Q 616
>At1g01460 [T] KOG0229 Phosphatidylinositol-4-phosphate 5-kinase
Length = 425
Score = 52.0 bits (123), Expect = 1e-05
Identities = 46/184 (25%), Positives = 81/184 (44%), Gaps = 14/184 (7%)
Query: 1818 SGGKSGSAFLKTLDDRFVIKELSHSELDAFINFSSSYFEYMSQALFHDLPTALAKILGFY 1877
S K G+ FL + DDRF+IK L SE+ + YF ++ + T L+K G +
Sbjct: 75 STSKVGNMFLLSKDDRFLIKILRKSEIKVILEMLPGYFRHIHKY----RSTLLSKNYGAH 130
Query: 1878 QIQIRNAATGKSFKMDVIIMENLFYEKKTSRIFDLKGSMRNRHVEQTGKENEVLLDENMV 1937
++ M I+ ++F K ++DLKGS + R ++ ++ +L + +
Sbjct: 131 SVKPIGGVKTYFVVMSNILQSDVFMNK----VYDLKGSSQGRTNKKIKVRDKTILKDIDL 186
Query: 1938 EYIYESPIFVREYDKKLLRASLWNDTLFLAKMNVMDYSLVVG--VDNQTHSLTVGIIDCI 1995
++ + +V + L D L +MDYSL++G V H +I
Sbjct: 187 DFCF----YVDSLARHRLIKQTKLDCELLEDEGIMDYSLMLGLQVKGSCHGSIDELIPVY 242
Query: 1996 RTFT 1999
+FT
Sbjct: 243 DSFT 246
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.316 0.132 0.379
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 118,640,351
Number of Sequences: 60738
Number of extensions: 5209475
Number of successful extensions: 19182
Number of sequences better than 1.0e-05: 84
Number of HSP's better than 0.0 without gapping: 31
Number of HSP's successfully gapped in prelim test: 53
Number of HSP's that attempted gapping in prelim test: 18952
Number of HSP's gapped (non-prelim): 153
length of query: 2054
length of database: 30,389,216
effective HSP length: 122
effective length of query: 1932
effective length of database: 22,979,180
effective search space: 44395775760
effective search space used: 44395775760
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)