ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIV1230 suspect: %id U KOG0946 Intracellular trafficking, secretion, and vesicular transport ER-Golgi vesicle-tethering protein p115
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIV1230 406024 408843 940
(940 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YDL058w [U] KOG0946 ER-Golgi vesicle-tethering protein p115 70 1e-11
Hs20558376 [Z] KOG0161 Myosin class II heavy chain 60 2e-08
SPAC1F3.06c [S] KOG4674 Uncharacterized conserved coiled-coil pr... 59 3e-08
Hs8923940 [Z] KOG0161 Myosin class II heavy chain 58 8e-08
Hs7669506 [Z] KOG0161 Myosin class II heavy chain 56 2e-07
Hs11024712 [Z] KOG0161 Myosin class II heavy chain 56 3e-07
Hs5031875 [DY] KOG0977 Nuclear envelope protein lamin intermedia... 55 5e-07
Hs4505301 [Z] KOG0161 Myosin class II heavy chain 55 5e-07
Hs11342672 [Z] KOG0161 Myosin class II heavy chain 55 5e-07
Hs8923838 [S] KOG4643 Uncharacterized coiled-coil protein 55 7e-07
SPAC1556.01c [L] KOG0962 DNA repair protein RAD50 ABC-type ATPas... 54 1e-06
SPCC162.08c [S] KOG4674 Uncharacterized conserved coiled-coil pr... 53 2e-06
CE06253 [Z] KOG0161 Myosin class II heavy chain 52 4e-06
CE24961 [DY] KOG0977 Nuclear envelope protein lamin intermediate... 51 7e-06
>YDL058w [U] KOG0946 ER-Golgi vesicle-tethering protein p115
Length = 1790
Score = 70.5 bits (171), Expect = 1e-11
Identities = 104/521 (19%), Positives = 222/521 (41%), Gaps = 55/521 (10%)
Query: 418 KENNHLRNMVKRLEKQRL-IDSTAHESKQEEFSKLTTI-------------HVQKLNDLE 463
K L+ + LE+ + I S + SK E S+++ + +V K+++L
Sbjct: 1022 KNIEQLKKTISDLEQTKEEIISKSDSSKDEYESQISLLKEKLETATTANDENVNKISELT 1081
Query: 464 RTLQEVEVQYSRQKAHNNSSLELVNTAMEGMTGVL----NLFFSQEFYEEWQKDTKDRID 519
+T +E+E + + K N + T+ + + V +L + E+ +TK +++
Sbjct: 1082 KTREELEAELAAYKNLKNELETKLETSEKALKEVKENEEHLKEEKIQLEKEATETKQQLN 1141
Query: 520 SLMVYLN-------DICQYFSTMQTEMILK-LEHNAEMNELTERCEFYTENCSLLERENE 571
SL L D+ + ++ K ++N E+++L + + ++++N+
Sbjct: 1142 SLRANLESLEKEHEDLAAQLKKYEEQIANKERQYNEEISQLNDEITSTQQENESIKKKND 1201
Query: 572 SLKAVASAYRQLQDIVTE-KNIIISSLEVENRSLKKQVETKAKDLELLSVKH-EREIAKL 629
L+ A + + + K I +L ++ + LKK+ ET L L S+K E E K+
Sbjct: 1202 ELEGEVKAMKSTSEEQSNLKKSEIDALNLQIKELKKKNETNEASL-LESIKSVESETVKI 1260
Query: 630 KDLSKAERGRILKVWDRTDYEKALDSKEEEIVKLNHRISLLDLIIDNKVTEIKNNESRYR 689
K+L + +V + D KA + K + ++L + +D K TE+K +
Sbjct: 1261 KELQDECNFKEKEVSELEDKLKASEDKNSKYLELQKESEKIKEELDAKTTELKIQLEKIT 1320
Query: 690 GL-------ETKVAILSNENIVLKSKHDEVIKKKKEDLAFFNEKFQKRLLAMKREIDKNA 742
L E++++ L + + +E ++K K ++ N+ F+K +
Sbjct: 1321 NLSKAKEKSESELSRLKKTSSEERKNAEEQLEKLKNEIQIKNQAFEKERKLLNEGSSTIT 1380
Query: 743 DMYHNELQSYRTNYEKTLSSALKVTLKAESALSAIYSNN----VDRFGSTNRTLNYFMKK 798
Y ++ TL L + L+ E+ L A +N +++ +N L +K
Sbjct: 1381 QEYSEKI--------NTLEDEL-IRLQNENELKAKEIDNTRSELEKVSLSNDEL--LEEK 1429
Query: 799 RDMFQNIRDNMVSNKPKPEYKPAITITSVSDGIENKDNRNEELHYISEQKQGFNDSLREL 858
++ ++++D ++S K K ++ D + ++ E+L E K + L++L
Sbjct: 1430 QNTIKSLQDEILSYKDKITRNDEKLLSIERDNKRDLESLKEQLRAAQESKAKVEEGLKKL 1489
Query: 859 KVANVNSNCSSRSKHNAKQIIQKLREWKQNQNTSELSPDKE 899
+ S+ +K++++KL E N +EL E
Sbjct: 1490 E---EESSKEKAELEKSKEMMKKL-ESTIESNETELKSSME 1526
Score = 63.9 bits (154), Expect = 1e-09
Identities = 140/667 (20%), Positives = 276/667 (40%), Gaps = 108/667 (16%)
Query: 160 ESKIDSSSATAVDVNEMSENQHLGKKKDETKDKQDFCGDGNTRLSKI-EKLLQNDRESKT 218
E I+ T D+ + E + K D +KD+ + +++S + EKL +
Sbjct: 1021 EKNIEQLKKTISDLEQTKEE--IISKSDSSKDEYE------SQISLLKEKLETATTANDE 1072
Query: 219 YVEKCSKFAKYY--MESVKFRYEDLEKECI------------FDPNVFNINEPSPLQKFK 264
V K S+ K +E+ Y++L+ E N ++ E +Q K
Sbjct: 1073 NVNKISELTKTREELEAELAAYKNLKNELETKLETSEKALKEVKENEEHLKEEK-IQLEK 1131
Query: 265 DAENKEKIISDPESPAFCVENDHESSKVQLRRKVGFVAQDGHEIQLFDSNLPPCTTERNK 324
+A ++ ++ + +E +HE QL++ +E Q+ + ER
Sbjct: 1132 EATETKQQLNSLRANLESLEKEHEDLAAQLKK---------YEEQIANK-------ERQY 1175
Query: 325 NHTIPPTSNGVLSTSNRIFKYTDSYNKFEDVTKLGPVPFPDLS--LKERMTALFELVGAP 382
N I ++ + ST ++ E K + S K + AL +
Sbjct: 1176 NEEISQLNDEITSTQQENESIKKKNDELEGEVKAMKSTSEEQSNLKKSEIDALNLQIKEL 1235
Query: 383 EELKECNDLRL--SLTCLHPCLAKILGFLWRNINVGLKENNHLRNMVKRLE----KQRLI 436
++ E N+ L S+ + KI L N KE + L + +K E K +
Sbjct: 1236 KKKNETNEASLLESIKSVESETVKIKE-LQDECNFKEKEVSELEDKLKASEDKNSKYLEL 1294
Query: 437 DSTAHESKQEEFSKLTTIHVQ--KLNDLERTLQEVEVQYSRQKAHNNSSLELVNTAMEGM 494
+ + K+E +K T + +Q K+ +L + ++ E + SR K ++ + +E +
Sbjct: 1295 QKESEKIKEELDAKTTELKIQLEKITNLSKAKEKSESELSRLKKTSSEERKNAEEQLEKL 1354
Query: 495 TGVLNLFFSQEFYEEWQKDTKDRIDSLMVYLNDICQYFSTMQTEMILKLEHNAEM----- 549
+ + + ++K+ K + + + +T++ E+I +L++ E+
Sbjct: 1355 KNEIQIK-----NQAFEKERKLLNEGSSTITQEYSEKINTLEDELI-RLQNENELKAKEI 1408
Query: 550 -NELTERCEFYTENCSLLERENESLKAVASAYRQLQDIVTEKNIIISSLEVENR----SL 604
N +E + N LLE + ++K++ +D +T + + S+E +N+ SL
Sbjct: 1409 DNTRSELEKVSLSNDELLEEKQNTIKSLQDEILSYKDKITRNDEKLLSIERDNKRDLESL 1468
Query: 605 KKQV----ETKAK------DLELLSVKHEREIAKLKDLSKAERGRI----------LKVW 644
K+Q+ E+KAK LE S K + E+ K K++ K I ++
Sbjct: 1469 KEQLRAAQESKAKVEEGLKKLEEESSKEKAELEKSKEMMKKLESTIESNETELKSSMETI 1528
Query: 645 DRTD--YEKALDSKEEEIVKLNHRISLLDLIIDNKVTEIKNNESRYR-------GLET-- 693
++D E++ S EE+I L H S L I+ +I+ +S+ R LET
Sbjct: 1529 RKSDEKLEQSKKSAEEDIKNLQHEKSDLISRINESEKDIEELKSKLRIEAKSGSELETVK 1588
Query: 694 --------KVAILSNENIVLKSKHDEVIKKKKEDLAFF--NEKFQKRLLAMKREIDKNAD 743
K+ I + EN VLKSK +++ ++ K+ A N++ ++ L + +E+++ D
Sbjct: 1589 QELNNAQEKIRINAEENTVLKSKLEDIERELKDKQAEIKSNQEEKELLTSRLKELEQELD 1648
Query: 744 MYHNELQ 750
+ Q
Sbjct: 1649 STQQKAQ 1655
Score = 60.8 bits (146), Expect = 9e-09
Identities = 115/560 (20%), Positives = 226/560 (39%), Gaps = 77/560 (13%)
Query: 423 LRNMVKRLEKQRLIDSTAHESKQEEFSKLTTIHVQKLNDLERTLQEVEVQYSRQKAHNNS 482
L N K L+++ I +++H S +E FS L T + L+ Q +V ++ K + +
Sbjct: 767 LTNEHKELDEKYQILNSSHSSLKENFSILETELKNVRDSLDEMTQLRDVLETKDKENQTA 826
Query: 483 SLELVNTAMEGMTGVLNLFFSQEFYEEWQKDTKDRIDSLMVYLNDICQYFSTMQTEMILK 542
LE +T + + L E +K +D I+ +
Sbjct: 827 LLEYKSTIHKQEDSIKTLEKGLETILSQKKKAEDGINKM--------------------- 865
Query: 543 LEHNAEMNELTERCEFYTENCSLLERENES-----LKAVASAYRQLQDIVTEKNIIISSL 597
++ L+ + ENC L++E + K S + +TE I +L
Sbjct: 866 ---GKDLFALSREMQAVEENCKNLQKEKDKSNVNHQKETKSLKEDIAAKITEIKAINENL 922
Query: 598 E---VENRSLKKQVETKAKDLELLSVK---HEREIAKLKDLSKAERGRILKVWDRTDYEK 651
E ++ +L K+ E +K+L + H+ +AKL + K+ + + + E
Sbjct: 923 EEMKIQCNNLSKEKEHISKELVEYKSRFQSHDNLVAKLTEKLKSLANNYKDM--QAENES 980
Query: 652 ALDSKEEEIVKLNHRISLLDLIIDNKVTEIKNNESRYRGLETKVAILSNENIVLKSKHDE 711
+ + EE + + ++S L ID+ E +N + +E + L L+ +E
Sbjct: 981 LIKAVEESKNESSIQLSNLQNKIDSMSQEKENFQIERGSIEKNIEQLKKTISDLEQTKEE 1040
Query: 712 VIKKK-------KEDLAFFNEKFQKRLLAMKREIDKNADM--YHNELQSYRTNYEKTLSS 762
+I K + ++ EK + A ++K +++ EL++ Y K L +
Sbjct: 1041 IISKSDSSKDEYESQISLLKEKLETATTANDENVNKISELTKTREELEAELAAY-KNLKN 1099
Query: 763 ALKVTLK-AESALSAIYSNNVDRFGSTNRTLNYFMKKRDMFQNIRDNMVSNKPKPEYKPA 821
L+ L+ +E AL + N + + + ++R N+ S + + E A
Sbjct: 1100 ELETKLETSEKALKEVKENEEHLKEEKIQLEKEATETKQQLNSLRANLESLEKEHE-DLA 1158
Query: 822 ITITSVSDGIENKDNR-NEELHYISEQ---KQGFNDSLR--------ELKVANVNSNCSS 869
+ + I NK+ + NEE+ ++++ Q N+S++ E+K S S
Sbjct: 1159 AQLKKYEEQIANKERQYNEEISQLNDEITSTQQENESIKKKNDELEGEVKAMKSTSEEQS 1218
Query: 870 RSKHNAKQIIQ-KLREWKQNQNTSELSPDKEDSIFSTGIET----------DYSTSNIAQ 918
K + + +++E K+ T+E S +SI S ET ++ +++
Sbjct: 1219 NLKKSEIDALNLQIKELKKKNETNEAS--LLESIKSVESETVKIKELQDECNFKEKEVSE 1276
Query: 919 LSTRNWASALKNNYNAKYLE 938
L + AS K N+KYLE
Sbjct: 1277 LEDKLKASEDK---NSKYLE 1293
Score = 50.8 bits (120), Expect = 1e-05
Identities = 80/495 (16%), Positives = 198/495 (39%), Gaps = 58/495 (11%)
Query: 418 KENNHLRNMVKRLEKQRLIDSTAHESKQEEFSKLTTIHVQKLNDLERTLQEVEVQ---YS 474
+E + K L+K++ + H+ + + + + ++ + L+E+++Q S
Sbjct: 874 REMQAVEENCKNLQKEKDKSNVNHQKETKSLKEDIAAKITEIKAINENLEEMKIQCNNLS 933
Query: 475 RQKAHNNSSLELVNTAMEGMTGVL-----NLFFSQEFYEEWQKDTKDRIDSLMVYLNDIC 529
++K H + L + + ++ L Y++ Q + + I ++ N+
Sbjct: 934 KEKEHISKELVEYKSRFQSHDNLVAKLTEKLKSLANNYKDMQAENESLIKAVEESKNESS 993
Query: 530 QYFSTMQTEMILKLEHNAEMNELTERCEFYTENCSLLERENESLKAVASAYRQLQDIVTE 589
S +Q +++ +++ E + +E+ E LK + + D+
Sbjct: 994 IQLSNLQN----------KIDSMSQEKENFQIERGSIEKNIEQLK------KTISDLEQT 1037
Query: 590 KNIIISSLEVENRSLKKQVETKAKDLELLSVKHEREIAKLKDLSKAERGRILKVWDRTDY 649
K IIS + + Q+ + LE + ++ + K+ +L+K ++ +
Sbjct: 1038 KEEIISKSDSSKDEYESQISLLKEKLETATTANDENVNKISELTKTREELEAELAAYKNL 1097
Query: 650 EKALDSKEEEIVKLNHRISLLDLIIDNKVTEIKNNESRYRGLE---TKVAILSNENIVLK 706
+ L++K E K + E+K NE + + K A + + +
Sbjct: 1098 KNELETKLETSEK--------------ALKEVKENEEHLKEEKIQLEKEATETKQQLNSL 1143
Query: 707 SKHDEVIKKKKEDLAFFNEKFQKRLLAMKREIDKNADMYHNELQSYRTNYE--KTLSSAL 764
+ E ++K+ EDLA +K+++++ +R+ ++ ++E+ S + E K + L
Sbjct: 1144 RANLESLEKEHEDLAAQLKKYEEQIANKERQYNEEISQLNDEITSTQQENESIKKKNDEL 1203
Query: 765 KVTLKAESALSAIYSN-NVDRFGSTNRTLNYFMKKRDM-------------FQNIRDNMV 810
+ +KA + S SN + N + KK + + ++ +
Sbjct: 1204 EGEVKAMKSTSEEQSNLKKSEIDALNLQIKELKKKNETNEASLLESIKSVESETVKIKEL 1263
Query: 811 SNKPKPEYKPAITITSVSDGIENKDNRNEELHYISEQ-KQGFNDSLRELKVANVNSNCSS 869
++ + K + E+K+++ EL SE+ K+ + ELK+ S
Sbjct: 1264 QDECNFKEKEVSELEDKLKASEDKNSKYLELQKESEKIKEELDAKTTELKIQLEKITNLS 1323
Query: 870 RSKHNAKQIIQKLRE 884
++K ++ + +L++
Sbjct: 1324 KAKEKSESELSRLKK 1338
>Hs20558376 [Z] KOG0161 Myosin class II heavy chain
Length = 1937
Score = 59.7 bits (143), Expect = 2e-08
Identities = 124/617 (20%), Positives = 228/617 (36%), Gaps = 118/617 (19%)
Query: 377 ELVGAPEELK-ECNDLRLSLTCLHPCLAKILGFLWRNIN---------VGLKEN----NH 422
EL +L+ EC++L+ + L LAK+ N GL E +
Sbjct: 938 ELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLSK 997
Query: 423 LRNMVKRLEKQRLIDSTAHESKQEEFSKLTTIHVQKLNDLERTLQEVEVQYSRQKAHNNS 482
+ ++ +Q L D A E K +K T Q+++DLE +L+ Q+
Sbjct: 998 EKKALQETHQQTLDDLQAEEDKVNILTKAKTKLEQQVDDLEGSLE--------QEKKLRM 1049
Query: 483 SLELVNTAMEGMTGVLNLFFSQEFYEEWQKDTKDRIDSLMVYLNDICQYFSTMQTEMILK 542
LE +EG +L +QE + + D + + L +I S ++ E ++
Sbjct: 1050 DLERAKRKLEG-----DLKLAQESTMDMENDKQQLDEKLEKKEFEISNLISKIEDEQAVE 1104
Query: 543 LEHNAEMNELTERCEFYTENCSLLERENESLKAVASAYRQLQDIVTEKNIIISSLEVENR 602
++ ++ EL R E E +E E S A A +Q D+ E I LE
Sbjct: 1105 IQLQKKIKELQARIEELGEE---IEAERASR---AKAEKQRSDLSRELEEISERLEEAGG 1158
Query: 603 SLKKQVETKAK----------DLELLSVKHEREIAKLKDL---SKAERG----RILKVWD 645
+ QVE K DLE +++HE +A L+ S AE G + +V
Sbjct: 1159 ATSAQVELNKKREAEFQKLRRDLEEATLQHEAMVAALRKKHADSMAELGEQIDNLQRVKQ 1218
Query: 646 RTDYEKA--------LDSKEEEIVKLNHRISLLDLIIDNKVTEIKNNESRY--------- 688
+ + EK+ L S E I K + + ++++V+E+K E
Sbjct: 1219 KLEKEKSELKMETDDLSSNAEAISKAKGNLEKMCRSLEDQVSELKTKEEEQQRLINDLTA 1278
Query: 689 -------------RGLETKVAILS--------------------NENIVLKSKHDEVIKK 715
R L+ K A++S E K+ ++
Sbjct: 1279 QRARLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQIEELKHQLEEETKAKNALAHALQS 1338
Query: 716 KKEDLAFFNEKFQKRLLAMKREIDKNADMYHNELQSYRTNYEKTLSSALKVTLKAESALS 775
+ D E++++ K E+ + ++E+ +RT YE + +A+ L+
Sbjct: 1339 SRHDCDLLREQYEEEQEG-KAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLA 1397
Query: 776 AIYSNNVDRFGSTNRTLNYFMKKRDMFQN-IRDNMVSNKPKPEYKPAITITSVSDGIENK 834
+ + N K + QN + D M+ + ++ + +K
Sbjct: 1398 QRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLD----------VERSNAACAALDK 1447
Query: 835 DNRNEELHYISEQKQGFNDSLRELKVANVNSNCSSRSKHNAKQIIQKLREW-----KQNQ 889
RN + +SE KQ + ++ EL+ + S S K + ++ + ++N+
Sbjct: 1448 KQRNFD-KVLSEWKQKYEETQAELEASQKESRSLSTELFKVKNVYEESLDQLETLRRENK 1506
Query: 890 NTSELSPDKEDSIFSTG 906
N + D + I G
Sbjct: 1507 NLQQEISDLTEQIAEGG 1523
>SPAC1F3.06c [S] KOG4674 Uncharacterized conserved coiled-coil protein
Length = 1957
Score = 59.3 bits (142), Expect = 3e-08
Identities = 152/759 (20%), Positives = 298/759 (39%), Gaps = 99/759 (13%)
Query: 175 EMSENQHLGKKKDETKDKQDFCGDGNTRLSKIEKLLQNDRESKTYVEKCSKFAKYYMESV 234
E+S ++HL + +++ N LS+ + LQ C+ F + +SV
Sbjct: 544 EISNSEHLSSQLSTLAAEKEAAVATNNELSESKNSLQT---------LCNAFQEKLAKSV 594
Query: 235 KFRYEDLEKECIFDPNVFNINEPSPLQKFKDAENKEKIISDPESPAFCVENDHESSKVQL 294
E+ + D + +NE ++ EN + I+ + +
Sbjct: 595 MQLKENEQNFSSLDTSFKKLNE-----SHQELENNHQTITKQLKDTSSKLQQLQLERANF 649
Query: 295 RRKVGFVAQDGHEIQLFDSNLPPCTTERNKNHTIPPTSNGVLSTSNRIFKYTDSYNKFED 354
+K ++ + ++++ L N ++ V S I + K E+
Sbjct: 650 EQKESTLSDENNDLRTKLLKL------EESNKSLIKKQEDVDSLEKNIQTLKEDLRKSEE 703
Query: 355 VTKLGPVPFPDLSLKERMTALFELVGAPEELK-ECNDLRLSLTCLHPCLAKILGFLWRNI 413
+ F L K + L G E L+ + NDL SL+ +N
Sbjct: 704 ALR-----FSKLEAKNLREVIDNLKGKHETLEAQRNDLHSSLSDA------------KNT 746
Query: 414 NVGLK-ENNHLRNMVKRLEKQRLIDSTAHESK--QEEFSKLTTIHVQKLNDLERTLQEVE 470
N L E VKRL +++ +SK ++ F+ L + Q +++L L++
Sbjct: 747 NAILSSELTKSSEDVKRLTAN--VETLTQDSKAMKQSFTSLVNSY-QSISNLYHELRDDH 803
Query: 471 VQYSRQKAHNNSSLEL---VNTAMEGMTGV-LNLFFSQEFYEEWQKDTKDRIDSLMVYLN 526
V Q NN+ LE + T E +T + L + + + + ++ L
Sbjct: 804 VNMQSQ---NNTLLESESKLKTDCENLTQQNMTLIDNVQKLMHKHVNQESKVSELKEVNG 860
Query: 527 DICQYFSTMQTEMILKLEHNAEMNELTERCEFYTENCSLLERENESLKA-VASAYRQLQD 585
+ +++ + + + N ++ LT+ E ++N LE+E+ L + + S + Q
Sbjct: 861 KLSLDLKNLRSSLNVAISDNDQI--LTQLAEL-SKNYDSLEQESAQLNSGLKSLEAEKQL 917
Query: 586 IVTEKNIIISSLEVENRSLKKQVETKAKDLELLSVKHEREIAKLKDLSKAERGRILKVWD 645
+ TE + L+ LK + E+K+ DL + EI+ LK+ + ++ I V
Sbjct: 918 LHTENEELHIRLDKLTGKLKIE-ESKSSDLGKKLTARQEEISNLKEENMSQSQAITSVKS 976
Query: 646 RTDYEKALDSK-EEEIVKLNHRISLLD-----LIIDNK--VTEIKNNESRYRGLETKVAI 697
+ D + SK E +I L +++S ++ L+ N+ + ++KNN L+T++
Sbjct: 977 KLDETLSKSSKLEADIEHLKNKVSEVEVERNALLASNERLMDDLKNNGENIASLQTEIEK 1036
Query: 698 LSNENIVLKSKHDEVIKKKKEDLAFFNEKFQKRLLAMKREIDKNADMYHNELQSYRTNYE 757
EN L+SK L+ + +++ LL + + +K+ + N+L+ N +
Sbjct: 1037 KRAENDDLQSK-----------LSVVSSEYE-NLLLISSQTNKSLEDKTNQLKYIEKNVQ 1084
Query: 758 KTLSSALKVTLKAESALSAIYSNNVDRFGSTNRTLNYFMKKRDMFQNIRDNMVSNKPKPE 817
K L + ++ E L++ Y + L KK ++ N V +
Sbjct: 1085 KLLDEKDQRNVELEE-LTSKYGKLGEENAQIKDELLALRKKSKKQHDLCANFVDD----- 1138
Query: 818 YKPAITITSVSDGIENKDNRNEELHYISEQKQGFNDSLRELK--VANVNSNCSSRSKHNA 875
+ SD +E N EL EQ N++L E + +AN S+ +S ++
Sbjct: 1139 ------LKEKSDALEQLTNEKNELIVSLEQSNSNNEALVEERSDLANRLSD-MKKSLSDS 1191
Query: 876 KQIIQKLRE--WKQNQNTSELSPDKEDSIFSTGIETDYS 912
+I +R + N L DK+ + T YS
Sbjct: 1192 DNVISVIRSDLVRVNDELDTLKKDKD------SLSTQYS 1224
>Hs8923940 [Z] KOG0161 Myosin class II heavy chain
Length = 1941
Score = 57.8 bits (138), Expect = 8e-08
Identities = 98/427 (22%), Positives = 177/427 (40%), Gaps = 42/427 (9%)
Query: 377 ELVGAPEELK-ECNDLRLSLTCLHPCLAKILGFLWRNINVGLKENNHLRNMVKRL-EKQR 434
EL +L+ EC++L+ + L LAK+ KE + N VK L E+
Sbjct: 941 ELTAKKRKLEDECSELKKDIDDLELTLAKVE-----------KEKHATENKVKNLTEEMA 989
Query: 435 LIDSTAHESKQEEFSKLTTIHVQKLNDLE------RTLQEVEVQYSRQKAHNNSSLEL-- 486
+D T + +E+ L H Q L+DL+ TL + +++ +Q SLE
Sbjct: 990 GLDETIAKLTKEK-KALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEK 1048
Query: 487 -----VNTAMEGMTGVLNLFFSQEFYEEWQKDTKDRIDSLMVYLNDICQYFSTMQTEMIL 541
+ A + G L L +QE + + + + + L +I S ++ E L
Sbjct: 1049 KLRMDLERAKRKLEGDLKL--AQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQAL 1106
Query: 542 KLEHNAEMNELTERCEFYTENCSLLERENESLKAV-ASAYRQLQDIVTEKNIIISSLEVE 600
++ ++ EL R E LE E E+ +A A A +Q D+ E I LE
Sbjct: 1107 GIQLQKKIKELQARIEE-------LEEEIEAERASRAKAEKQRSDLSRELEEISERLEEA 1159
Query: 601 NRSLKKQVE-TKAKDLELLSVKHEREIAKLKDLSKAERGRILKVWDRTDYEKALDSKEEE 659
+ Q+E K ++ E ++ + E A L+ + A R + + +D+ +
Sbjct: 1160 GGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRV 1219
Query: 660 IVKLNHRISLLDLIIDNKVTEIKNNESRYRGLETKVAILSNENIVLKSKHDEVIKKKKED 719
KL S + + ID+ + ++ LE L ++ LKSK +E ++ D
Sbjct: 1220 KQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQ-QRLIND 1278
Query: 720 LAFFNEKFQKRLLAMKREIDKNADMYHNELQSYR--TNYEKTLSSALKVTLKAESALS-A 776
L + Q R++D+ + + + T + L L+ +KA++AL+ A
Sbjct: 1279 LTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHA 1338
Query: 777 IYSNNVD 783
+ S+ D
Sbjct: 1339 LQSSRHD 1345
>Hs7669506 [Z] KOG0161 Myosin class II heavy chain
Length = 1939
Score = 56.2 bits (134), Expect = 2e-07
Identities = 121/564 (21%), Positives = 224/564 (39%), Gaps = 63/564 (11%)
Query: 377 ELVGAPEELK-ECNDLRLSLTCLHPCLAKILGFLWRNINVGLKENNHLRNMVKRL-EKQR 434
EL +L+ EC++L+ + L LAK+ KE + N VK L E+
Sbjct: 939 ELTAKKRKLEDECSELKKDIDDLELTLAKVE-----------KEKHATENKVKNLTEEMA 987
Query: 435 LIDSTAHESKQEEFSKLTTIHVQKLNDLE------RTLQEVEVQYSRQKAHNNSSLEL-- 486
+D T + +E+ L H Q L+DL+ TL + +++ +Q SLE
Sbjct: 988 GLDETIAKLTKEK-KALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEK 1046
Query: 487 -----VNTAMEGMTGVLNLFFSQEFYEEWQKDTKDRIDSLMVYLNDICQYFSTMQTEMIL 541
+ A + G L L +QE + + D + + L ++ S ++ E L
Sbjct: 1047 KIRMDLERAKRKLEGDLKL--AQESAMDIENDKQQLDEKLKKKEFEMSGLQSKIEDEQAL 1104
Query: 542 KLEHNAEMNELTERCEFYTENCSLLERENESLKAV-ASAYRQLQDIVTEKNIIISSLEVE 600
++ ++ EL R E LE E E+ +A A A +Q D+ E I LE
Sbjct: 1105 GMQLQKKIKELQARIEE-------LEEEIEAERASRAKAEKQRSDLSRELEEISERLEEA 1157
Query: 601 NRSLKKQVE-TKAKDLELLSVKHEREIAKLKDLSKAERGRILKVWDRTDYEKALDSKEEE 659
+ Q+E K ++ E ++ + E A L+ + A R + + +D+ +
Sbjct: 1158 GGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRV 1217
Query: 660 IVKLNHRISLLDLIIDNKVTEIKNNESRYRGLETKVAILSNENIVLKSKHDEVIKKKKED 719
KL S + + ID+ + ++ LE L ++ +K+K +E ++ D
Sbjct: 1218 KQKLEKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRALEDQLSEIKTKEEEQ-QRLIND 1276
Query: 720 LAFFNEKFQKRLLAMKREIDKNADMYHNELQSYR---TNYEKTLSSALKVTLKAESALS- 775
L + Q R++D+ D ++L + T + L L+ +KA+SAL+
Sbjct: 1277 LTAQRARLQTESGEYSRQLDEK-DTLVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAH 1335
Query: 776 AIYSNNVD---------RFGSTNRTLNYFMKKRD-----MFQNIRDNMVSNKPKPEYKPA 821
A+ S+ D L M K + + + + E
Sbjct: 1336 ALQSSRHDCDLLREQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKK 1395
Query: 822 ITITSVSDGIENKDNRNEELHYISEQKQGFNDSLREL--KVANVNSNCSSRSKHNAKQII 879
+ D E+ + N + + + KQ + + +L V N+ C++ K +
Sbjct: 1396 KLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDK-KQRNFD 1454
Query: 880 QKLREWKQ--NQNTSELSPDKEDS 901
+ L EWKQ + +EL +++S
Sbjct: 1455 KILAEWKQKCEETHAELEASQKES 1478
>Hs11024712 [Z] KOG0161 Myosin class II heavy chain
Length = 1939
Score = 55.8 bits (133), Expect = 3e-07
Identities = 120/576 (20%), Positives = 226/576 (38%), Gaps = 87/576 (15%)
Query: 377 ELVGAPEELK-ECNDLRLSLTCLHPCLAKILGFLWRNINVGLKENNHLRNMVKRL-EKQR 434
EL +L+ EC++L+ + L LAK+ KE + N VK L E+
Sbjct: 939 ELTAKKRKLEDECSELKKDIDDLELTLAKVE-----------KEKHATENKVKNLTEEMA 987
Query: 435 LIDSTAHESKQEEFSKLTTIHVQKLNDLE------RTLQEVEVQYSRQKAHNNSSLEL-- 486
+D T + +E+ L H Q L+DL+ TL + + + +Q SLE
Sbjct: 988 GLDETIAKLTKEK-KALQEAHQQTLDDLQMEEDKVNTLTKAKTKLEQQVDDLEGSLEQEK 1046
Query: 487 -----VNTAMEGMTGVLNLFFSQEFYEEWQKDTKDRIDSLMVYLNDICQYFSTMQTEMIL 541
+ A + G L L +QE + + D + + L ++ ++ E L
Sbjct: 1047 KLCMDLERAKRKLEGDLKL--AQESTMDTENDKQQLNEKLKKKEFEMSNLQGKIEDEQAL 1104
Query: 542 KLEHNAEMNELTERCEFYTENCSLLERENESLKAV-ASAYRQLQDIVTEKNIIISSLEVE 600
++ ++ EL R E LE E E+ +A A A +Q D+ E I LE
Sbjct: 1105 AMQLQKKIKELQARIEE-------LEEEIEAERASRAKAEKQRSDLSRELEEISERLEEA 1157
Query: 601 NRSLKKQVETKAK----------DLELLSVKHEREIAKLKDL---SKAERGR----ILKV 643
+ Q+E K DLE +++HE A L+ S AE G+ + +V
Sbjct: 1158 GGATSAQIELNKKREAEFQKMRRDLEESTLQHEATAAALRKKHADSVAELGKQIDSLQRV 1217
Query: 644 WDRTDYEKA--------LDSKEEEIVKLNHRISLLDLIIDNKVTEIKNNESRYRGLETKV 695
+ + EK+ L S E + K + ++++++EIK E + L +
Sbjct: 1218 KQKLEKEKSELKMEINDLASNMETVSKAKANFEKMCRTLEDQLSEIKTKEEEQQRL---I 1274
Query: 696 AILSNENIVLKSKHDEVIKKKKE------DLAFFNEKFQKRLLAMKREIDKNADMYHNEL 749
LS + L ++ E ++ E L+ + F +++ +KR++++
Sbjct: 1275 NELSAQKARLHTESGEFSRQLDEKDAMVSQLSRGKQAFTQQIEELKRQLEE--------- 1325
Query: 750 QSYRTNYEKTLSSALKVTLKAESALSAIYSNNVDRFGSTNRTLNYFMKKRDMFQ-NIRDN 808
T + TL+ AL+ L Y + R ++ + ++ +
Sbjct: 1326 ---ETKAKSTLAHALQSARHDCDLLREQYEEEQEAKAELQRGMSKANSEVAQWRTKYETD 1382
Query: 809 MVSNKPKPEYKPAITITSVSDGIENKDNRNEELHYISEQKQGFNDSLRELKVANVNSNCS 868
+ + E + D E+ + N + + + KQ + + +L + SN +
Sbjct: 1383 AIQRTEELEEAKKKLAQRLQDAEEHVEAVNSKCASLEKTKQRLQNEVEDLMIDVERSNAA 1442
Query: 869 SRSKHNAKQIIQK-LREWKQ--NQNTSELSPDKEDS 901
+ ++ K L EWKQ + +EL +++S
Sbjct: 1443 CIALDKKQRNFDKVLAEWKQKYEETQAELEASQKES 1478
>Hs5031875 [DY] KOG0977 Nuclear envelope protein lamin intermediate filament
superfamily
Length = 572
Score = 55.1 bits (131), Expect = 5e-07
Identities = 50/221 (22%), Positives = 100/221 (44%), Gaps = 20/221 (9%)
Query: 540 ILKLEHNAEMNELTERCEFYTENCSLLERENESLKAVASAYRQLQDIVTEKNIIISSLEV 599
I +L+ ++ EL +R Y + LE EN L+ + ++ + E + I ++ E
Sbjct: 26 ITRLQEKEDLQELNDRLAVYIDRVRSLETENAGLRLRITESEEV--VSREVSGIKAAYEA 83
Query: 600 ENRSLKKQVETKAKDLELLSVKHEREIAKLKDLSKAERGRILKVWDRTDYEKALDSKEEE 659
E +K +++ AK+ L + E++K+++ K + R K KE +
Sbjct: 84 ELGDARKTLDSVAKERARLQL----ELSKVREEFKELKARNTK-------------KEGD 126
Query: 660 IVKLNHRISLLDLIIDNKVTEIKNNESRYRGLETKVAILSNENIVLKSKHDEVIKKKKED 719
++ R+ L+ ++++K + S R LE ++ L + L++ E KK+ +D
Sbjct: 127 LIAAQARLKDLEALLNSKEAALSTALSEKRTLEGELHDLRGQVAKLEAALGEA-KKQLQD 185
Query: 720 LAFFNEKFQKRLLAMKREIDKNADMYHNELQSYRTNYEKTL 760
+ RL MK E+D ++Y EL+ + +E L
Sbjct: 186 EMLRRVDAENRLQTMKEELDFQKNIYSEELRETKRRHETRL 226
>Hs4505301 [Z] KOG0161 Myosin class II heavy chain
Length = 1937
Score = 55.1 bits (131), Expect = 5e-07
Identities = 119/570 (20%), Positives = 222/570 (38%), Gaps = 75/570 (13%)
Query: 377 ELVGAPEELK-ECNDLRLSLTCLHPCLAKILGFLWRNIN---------VGLKEN----NH 422
EL +L+ EC++L+ + L LAK+ N GL E +
Sbjct: 938 ELTAKKRKLEDECSELKKDIDDLELTLAKVEKQKHATENKVKNLTEEMAGLDETIAKLSK 997
Query: 423 LRNMVKRLEKQRLIDSTAHESKQEEFSKLTTIHVQKLNDLERTLQEVEVQYSRQKAHNNS 482
+ ++ +Q L D A E K +K T Q+++DLE +L+ Q+
Sbjct: 998 EKKALQETHQQTLDDLQAEEDKVNILTKAKTKLEQQVDDLEGSLE--------QEKKLRM 1049
Query: 483 SLELVNTAMEGMTGVLNLFFSQEFYEEWQKDTKDRIDSLMVYLNDICQYFSTMQTEMILK 542
LE +EG +L +QE + + D + + L +I S ++ E ++
Sbjct: 1050 DLERAKRKLEG-----DLKLAQESTMDMENDKQQLDEKLEKKEFEISNLISKIEDEQAVE 1104
Query: 543 LEHNAEMNELTERCEFYTENCSLLERENESLKAVASAYRQLQDIVTEKNIIISSLEVENR 602
++ ++ EL R E E +E E S A A +Q D+ E I LE
Sbjct: 1105 IQLQKKIKELQARIEELGEE---IEAERASR---AKAEKQRSDLSRELEEISERLEEAGG 1158
Query: 603 SLKKQVETKAK----------DLELLSVKHEREIAKLKDL---SKAERG----RILKVWD 645
+ QVE K DLE +++HE +A L+ S AE G + +V
Sbjct: 1159 ATSAQVELNKKREAEFQKLRRDLEEATLQHEAMVAALRKKHADSMAELGEQIDNLQRVKQ 1218
Query: 646 RTDYEKA--------LDSKEEEIVKLNHRISLLDLIIDNKVTEIKNNESRYRGLETKVAI 697
+ + EK+ L S E I K + + ++++V+ +K E + L +
Sbjct: 1219 KLEKEKSELKMETDDLSSNAEAISKAKGHLEKMCRSLEDQVSGLKTKEEEQQRL---IND 1275
Query: 698 LSNENIVLKSKHDEVIKKKKEDLAFFNEKFQKRLLAMKREIDKNADMYHNELQSYRTNYE 757
L+ + L+++ E ++ E A ++ L K+ + + ++L+ T +
Sbjct: 1276 LTAQRARLQTEAGEYSRQLDEQDALVSQ-----LSRSKQASTQQIEELKHQLEE-ETKAK 1329
Query: 758 KTLSSALKVTLKAESALSAIYSNNVDRFGSTNRTLNYFMKK----RDMFQNIRDNMVSNK 813
L+ AL+ + L Y + R L+ + R ++
Sbjct: 1330 NALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEEL 1389
Query: 814 PKPEYKPAITITSVSDGIENKDNRNEELHYISEQKQGFNDSLRELKVANVNSNCSSRSKH 873
+ + K A + + +E + + L ++ Q + L L V N+ C++ K
Sbjct: 1390 EEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLM-LDVERSNAACAALDK- 1447
Query: 874 NAKQIIQKLREWKQ--NQNTSELSPDKEDS 901
+ + L EWKQ + +EL +++S
Sbjct: 1448 KQRNFDKVLSEWKQKYEETQAELEASQKES 1477
>Hs11342672 [Z] KOG0161 Myosin class II heavy chain
Length = 1940
Score = 55.1 bits (131), Expect = 5e-07
Identities = 120/550 (21%), Positives = 220/550 (39%), Gaps = 58/550 (10%)
Query: 377 ELVGAPEELK-ECNDLRLSLTCLHPCLAKILGFLWRNINVGLKENNHLRNMVKRL-EKQR 434
EL +L+ EC++L+ + L LAK+ KE + N VK L E+
Sbjct: 936 ELTAKKRKLEDECSELKKDIDDLELTLAKVE-----------KEKHATENKVKNLTEELS 984
Query: 435 LIDSTAHESKQEEFSKLTTIHVQKLNDLE------RTLQEVEVQYSRQKAHNNSSLEL-- 486
+D T + +E+ L H Q L+DL+ +L + + + +Q SSLE
Sbjct: 985 GLDETIAKLTREK-KALQEAHQQALDDLQAEEDKVNSLNKTKSKLEQQVEDLESSLEQEK 1043
Query: 487 -----VNTAMEGMTGVLNLFFSQEFYEEWQKDTKDRIDSLMVYLNDICQYFSTMQTEMIL 541
+ + G L L +QE + + D + + L + CQ S ++ E L
Sbjct: 1044 KLRVDLERNKRKLEGDLKL--AQESILDLENDKQQLDERLKKKDFEYCQLQSKVEDEQTL 1101
Query: 542 KLEHNAEMNELTERCEFYTENCSLLERENESLKAV-ASAYRQLQDIVTEKNIIISSLEVE 600
L+ ++ EL R E LE E E+ +A A +Q D E + LE
Sbjct: 1102 GLQFQKKIKELQARIE-------ELEEEIEAERATRAKTEKQRSDYARELEELSERLEEA 1154
Query: 601 NRSLKKQVE-TKAKDLELLSVKHEREIAKLKDLSKAERGRILKVWDRTDYEKALDSKEEE 659
Q+E K ++ E L ++ + E A L+ + R + + +D+ +
Sbjct: 1155 GGVTSTQIELNKKREAEFLKLRRDLEEATLQHEAMVATLRKKHADSVAELGEQIDNLQRV 1214
Query: 660 IVKLNHRISLLDLIIDNKVTEIKNNESRYRGLETKVAILSNENIVLKSKHDEVIKKKKED 719
KL S L ID+ + +++ LE L ++ + K++E I++ +
Sbjct: 1215 KQKLEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEE-IQRSLSE 1273
Query: 720 LAFFNEKFQKRLLAMKREIDKNADMYHNELQSYR--TNYEKTLSSALKVTLKAESALSAI 777
L + Q + R++++ + +S + T + L L+ KA++AL+
Sbjct: 1274 LTTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEENKAKNALA-- 1331
Query: 778 YSNNVDRFGSTNRTLNYFMKKRDMFQNIRDNMVSNKPKPEYKPAITITSV-SDGIENKDN 836
S+ + ++ + Q + + K + A T +D I+
Sbjct: 1332 -----HALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQ---- 1382
Query: 837 RNEELHYISEQ-KQGFNDSLRELKVANVNSNCSS--RSKHNAKQIIQKLREWKQNQNTSE 893
R EEL E+ Q DS E +V VN+ C+S ++K + ++ L + N+
Sbjct: 1383 RTEELEEAQEKLAQRLQDS--EEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERANSLA 1440
Query: 894 LSPDKEDSIF 903
+ DK+ F
Sbjct: 1441 AALDKKQRNF 1450
>Hs8923838 [S] KOG4643 Uncharacterized coiled-coil protein
Length = 742
Score = 54.7 bits (130), Expect = 7e-07
Identities = 91/380 (23%), Positives = 153/380 (39%), Gaps = 61/380 (16%)
Query: 417 LKENNHLRNMVKRLEKQRLIDSTAHESKQEEFSKLTTIHVQKLNDLERTLQEVEVQYSRQ 476
LKE+N + K + + +L + A K E K KL+D+E ++++ + +
Sbjct: 274 LKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEME-RDMDRKKIEE 332
Query: 477 KAHNNSSLELVNTAMEGMTGVLNLFFSQEFYEEWQKDTKDRIDSLMVYLNDICQYFSTMQ 536
N +LE+ QK + D L L I + S +
Sbjct: 333 LMEENMTLEMA-----------------------QKQSMDESLHLGWELEQISRT-SELS 368
Query: 537 TEMILKLEHNAEMNELTERCEFYTENCSLLERENESLKAVASAYRQLQDIVTEKNIIISS 596
L H E+NELT + LE EN+SL R D V I
Sbjct: 369 EAPQKSLGH--EVNELT------SSRLLKLEMENQSLTKTVEELRTTVDSVEGNASKILK 420
Query: 597 LEVENRSLKKQVETKAKDLELLSVKHEREIAKLKDLSK---AERGRILKVWD--RTDYEK 651
+E EN+ L K+VE LE V+ ++ + ++LSK E+ ++ K + R + E+
Sbjct: 421 MEKENQRLSKKVEI----LENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSER 476
Query: 652 ALDSKEEEIVKLNHRISLL-------------DLIIDNKV--TEIKNNESRYRGLETKVA 696
+ E+E LN +S L D+ +NK+ IK S+ +E +
Sbjct: 477 QIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEFEKR 536
Query: 697 ILSNENIVLKSKHD--EVIKKKKEDLAFFNEKFQKRLLAMKREIDK--NADMYHNELQSY 752
+ E K K + E ++ + L NE QK++ +K +K + ++EL+
Sbjct: 537 QIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEKIEALEQENSELERE 596
Query: 753 RTNYEKTLSSALKVTLKAES 772
+KTL S +T + ES
Sbjct: 597 NRKLKKTLDSFKNLTFQLES 616
>SPAC1556.01c [L] KOG0962 DNA repair protein RAD50 ABC-type ATPase/SMC
superfamily
Length = 658
Score = 53.5 bits (127), Expect = 1e-06
Identities = 81/394 (20%), Positives = 180/394 (45%), Gaps = 52/394 (13%)
Query: 413 INVGLKENNHLRNMVKRLEKQ-----RLIDSTAHESKQEEFSKLTTIHVQKLNDL-ERTL 466
++ LK + +R+ V+ L+++ RL D +++ E +T H++ +D+ T+
Sbjct: 225 VHESLKRISCIRSKVEELDQEITETARLQDELFKSTEEYEQQMITIRHLESQSDIINTTI 284
Query: 467 QEVEVQYSRQKAHNNSSLELVNTAMEGMTGVLNLFFSQEF----YEEWQKDTKDRIDSLM 522
+++ Q + + +L + E + L+ S E E K ++ ++ L
Sbjct: 285 NDLKSQMTITDESSEDLEKLHSNFAEKVKEEQELYKSLEKKRSDLESLLKSRRELLEKLT 344
Query: 523 VYLNDI------CQYFSTMQTEMILKLEHNAEMNELTER--CEFYTENCSLLERENE--- 571
L I + ++ MI ++ H +NE+ E ++ SL+ + E
Sbjct: 345 GDLGKIQGEIESLEKLKVKKSTMINEIVHRYNINEINEEGIMTEVSKYASLVNKNYEISS 404
Query: 572 -SLKAVASAYR-QLQDIVTEKNIIISSLEVENRSLKKQVETKAKDLE-----LLSVKHER 624
LK A R +++ I + + + + N SL+KQ+ T+ K+L L VK +R
Sbjct: 405 GKLKERQVAVRARIEGIKAHEMFLNNRVSEINSSLEKQLTTQ-KELRSRFEILFPVKLQR 463
Query: 625 EIAKLKDLSKAERG--RILKVWDRTDYEKALDSKEEEIVKLNHRISLLDLIIDNKVTEIK 682
E KD+ K++ + + ++ + + LD + + + +R+ ++++EI
Sbjct: 464 EDFT-KDVEKSDLWIKSLRQEYESKNLLELLDKHQTALSSVENRL--------DEISEIV 514
Query: 683 NNESRYRGLETKV-----------AILSNENIVLKSKHDEVIKKKKEDLAFFNEKFQKRL 731
++ +Y G+ TK+ AIL+N+ + LKS EV+ + +D +NE+ K +
Sbjct: 515 DSYHKYSGVRTKLQVFEENKTNKSAILANQLMTLKSSFSEVMSYELKDDDNYNEELDKLV 574
Query: 732 LAMKREIDKNADMYHNELQSYRTNYEKTLSSALK 765
+++++ + + + L+S R E +S +++
Sbjct: 575 EDVRKKLQEKEEA-ESSLRSVRERLEIRISLSVQ 607
>SPCC162.08c [S] KOG4674 Uncharacterized conserved coiled-coil protein
Length = 1837
Score = 53.1 bits (126), Expect = 2e-06
Identities = 61/284 (21%), Positives = 125/284 (43%), Gaps = 32/284 (11%)
Query: 626 IAKLKDLSKAERGRILKVWDRTDYEKALDSKEEEIVKLNHRISLLD---LIIDNKVTEIK 682
I+K KD + RI+ +YE+ L + E+++++ N R LL+ +++N++++IK
Sbjct: 42 ISKSKDYESIKNDRIVT---EVNYEQQLRNSEKKLLQSNERYDLLEDERKLLENELSQIK 98
Query: 683 ----NNESRYRGLETKVAILSNENIVLKSKHDEVIKKKKEDLAFFNEK---FQKRLLAMK 735
S Y + + L + N LK D+ +K+ + ++K +K++ +K
Sbjct: 99 EYLREKSSSYDTVLHDCSSLKSVNEALKQAQDQNLKQTAQLQNLLSDKEKEVEKKITIIK 158
Query: 736 REIDKNADMYHNELQSYRTNYEK-TLSSALKVTLKAESALSAIYSNNVDRFGSTNRTLNY 794
D A H L+ T EK +L + + L+ + ++I NN N
Sbjct: 159 DLKDALASSTHQVLELQHTQQEKASLQTNYEFELQKLTQKNSILENN-----------NT 207
Query: 795 FMKKRDMFQNIRDNMVSNKPKPEYKPAITITSVSDGIENKDNRNEELHYISEQKQGFNDS 854
++ + Q + D ++S + + + + +SD + KD ++ +S+Q F +S
Sbjct: 208 WLSRE--LQGVNDKLLSLHQEASLEKSQLSSQLSDAVLEKDALQRKVSSLSQQ---FTES 262
Query: 855 LRELKVANVNSNCSSRSKHNAKQIIQKLREWKQNQNTSELSPDK 898
L+ N+ + S K + +E + SEL +K
Sbjct: 263 --NLRYQNIVAELSEMRKQYEFSQVSFEKEISSQKQISELWMEK 304
Score = 51.2 bits (121), Expect = 7e-06
Identities = 88/422 (20%), Positives = 169/422 (39%), Gaps = 96/422 (22%)
Query: 429 RLEKQRLIDSTAHESKQEEFSKLTTIHVQKLNDLERTLQEVEVQYSRQKAHNNSSLELVN 488
R +++L+ S E+ KL +L+ ++ L+E Y H+ SSL+ VN
Sbjct: 67 RNSEKKLLQSNERYDLLEDERKLLE---NELSQIKEYLREKSSSYDTV-LHDCSSLKSVN 122
Query: 489 TAMEG-------MTGVLNLFFSQEFYEEWQKDT--KDRIDSLMVYLNDICQYFSTMQTEM 539
A++ T L S + E +K T KD D+L + + + T Q +
Sbjct: 123 EALKQAQDQNLKQTAQLQNLLSDKEKEVEKKITIIKDLKDALASSTHQVLELQHTQQEKA 182
Query: 540 ILKLEHNAEMNELTERCEFYTENCSLLERENE-------SLKAVASAYR-----QLQDIV 587
L+ + E+ +LT++ N + L RE + SL AS + QL D V
Sbjct: 183 SLQTNYEFELQKLTQKNSILENNNTWLSRELQGVNDKLLSLHQEASLEKSQLSSQLSDAV 242
Query: 588 TEKNII---ISSL-------EVENRSLKKQVETKAKDLELLSVKHEREIAKLKDLSKA-- 635
EK+ + +SSL + +++ ++ K E V E+EI+ K +S+
Sbjct: 243 LEKDALQRKVSSLSQQFTESNLRYQNIVAELSEMRKQYEFSQVSFEKEISSQKQISELWM 302
Query: 636 ---------------ERGRILKVWD--RTDYEKALDSKEEEIVKLNHRISLLDLIIDNKV 678
G + K+ + ++ +E+ L+S +E L +I+ L+ + +
Sbjct: 303 EKCEDCSLRLKELQNSNGELEKLLEAAQSSFEEQLESHKEAEASLKSQINFLEKEVSSLE 362
Query: 679 TEIK----------------NNESRYRGL----------ETKVAILSNENIVLKSKHDEV 712
+++K +E +Y L ++ V+ L +E + K K+++
Sbjct: 363 SQLKLANERLRHYDEIEISDMSELKYSNLLNNSMKGFKGQSSVSDLYSERLYYKQKYEQT 422
Query: 713 IKKKKEDLAFFNEKFQ-------------KRLLAMKREIDKNADMYHNEL---QSYRTNY 756
++ + +N + KR M+REI ++ Y L Q ++ Y
Sbjct: 423 CQEVERLQRSYNHVMEEANLQHPLVKEQFKRFAHMQREIVAMSEQYQKSLEDCQKAKSRY 482
Query: 757 EK 758
E+
Sbjct: 483 EQ 484
>CE06253 [Z] KOG0161 Myosin class II heavy chain
Length = 1938
Score = 52.0 bits (123), Expect = 4e-06
Identities = 151/814 (18%), Positives = 300/814 (36%), Gaps = 114/814 (14%)
Query: 160 ESKIDSSSATAVDVNEMSENQHLGKKKDETKDKQDFCGDGNTRLSKIEKLLQNDRESKTY 219
+SK ++ ++ E Q K + Q + N RL + K L+ +++
Sbjct: 1114 QSKENAQRIIEIEDELEHERQSRSKADRARAELQRELDELNERLDEQNKQLEIQQDNNK- 1172
Query: 220 VEKCSKFAKYYMESVKFRYEDLEKECIFDPNVFNI------------NEPSPLQKFKDAE 267
K E +KFR + EK + + I N LQK K
Sbjct: 1173 --------KKDSEIIKFRRDLDEKNMANEDQMAMIRRKNNDQISALTNTLDALQKSKAKI 1224
Query: 268 NKEKIISDPESPAFCVENDHES-SKVQLRRKVGFVAQDGHEIQLFDSNLPPCTTERNKNH 326
KEK + E + D E+ S+V+ R +EIQ+ + L E+++
Sbjct: 1225 EKEKGVLQKELDDINAQVDQETKSRVEQERLA-----KQYEIQV--AELQQKVDEQSRQI 1277
Query: 327 TIPPTSNGVLSTSNR-IFKYTDSYNKFEDVTKLGPVPFPDLSLKERMTALFELVGAPEEL 385
++ G LS N + + + F ++ + A EL E
Sbjct: 1278 GEYTSTKGRLSNDNSDLARQVEELEIHLATINRAKTAFSSQLVEAKKAAEDELHERQEFH 1337
Query: 386 KECNDLRLSLTCLHPCLAKILGF---LWRNINVGLKENNHLRNMVKRLEKQRLIDSTAHE 442
C +L L H L + + + R ++ + N+ + R E + L+ S
Sbjct: 1338 AACKNLEHELDQCHELLEEQINGKDDIQRQLS---RINSEISQWKARYEGEGLVGS---- 1390
Query: 443 SKQEEFSKLTTIHVQKLNDLERTLQEVEVQY-SRQKAHNNSSLELVNTAME---GMTGVL 498
EE +L + ++ DL+ L + + S +KA E + + +T +
Sbjct: 1391 ---EELEELKRKQMNRVMDLQEALSAAQNKVISLEKAKGKLLAETEDARSDVDRHLTVIA 1447
Query: 499 NLFFSQEFYEEWQKDTKDRIDSLMVYLNDICQYFSTMQTEMILKLEHNAEMNELTERCEF 558
+L Q +++ D K ++D + ++ + TE + KL + M+ L+E+ E
Sbjct: 1448 SLEKKQRAFDKIVDDWKRKVDDIQKEIDATTRDSRNTSTE-VFKLR--SSMDNLSEQIET 1504
Query: 559 YTENCSLLERE----NESLKAVASAYRQLQDIVT-----------------------EKN 591
+ +E NE + Y+++ V E
Sbjct: 1505 LRRENKIFSQEIRDINEQITQGGRTYQEVHKSVRRLEQEKDELQHALDEAEAALEAEESK 1564
Query: 592 IIISSLEVEN--RSLKKQVETKAKDLELLSVKHEREIAKLKDL------SKAERGRILKV 643
++ +EV+ ++K+++ K ++ E H+R + ++ SKAE R K
Sbjct: 1565 VLRLQIEVQQIRSEIEKRIQEKEEEFENTRKNHQRALESIQASLETEAKSKAELARAKKK 1624
Query: 644 W--DRTDYEKALD-------SKEEEIVKLNHRISLLDLIIDNKVTEIKNNESRYRGLETK 694
D E ALD ++ + KL ++ L +D++ + Y E +
Sbjct: 1625 LETDINQLEIALDHANKANVDAQKNLKKLFDQVKELQGQVDDEQRRREEIRENYLAAEKR 1684
Query: 695 VAILSNEN------IVLKSKHDEVIKKKKEDLAFFNEKF---QKRLLAMKREIDKNADMY 745
+AI +E+ I KH + ++ ++ +L N + L AMKR+++ +
Sbjct: 1685 LAIALSESEDLAHRIEASDKHKKQLEIEQAELKSSNTELIGNNAALSAMKRKVENEVQIA 1744
Query: 746 HNELQSYRTNYEKTLSSALKVTLKAESALSAIYSNNVDRFGSTNRTLNYFMKKRDMFQNI 805
NEL Y + + A K A+ + + + + +++ I
Sbjct: 1745 RNELDEYLNELKASEERARKAAADADRLAEEVRQEQEHAVHVDRQRKSLELNAKELQAKI 1804
Query: 806 RD---NMVSNKPKPEYKPAITITSVSDGIENKDNRNEE--LHYISEQKQGFNDSLRELKV 860
D M+ K K + S+ + ++ R++E Y ++++ REL+
Sbjct: 1805 DDAERAMIQFGAKALAKVEDRVRSLEAELHSEQRRHQESIKGYTKQERRA-----RELQF 1859
Query: 861 -ANVNSNCSSRSKHNAKQIIQKLREWKQNQNTSE 893
+ R + N +++ QK+R K+ +E
Sbjct: 1860 QVEEDKKAFDRLQENVEKLQQKIRVQKRQIEEAE 1893
>CE24961 [DY] KOG0977 Nuclear envelope protein lamin intermediate filament
superfamily
Length = 592
Score = 51.2 bits (121), Expect = 7e-06
Identities = 87/397 (21%), Positives = 167/397 (41%), Gaps = 66/397 (16%)
Query: 548 EMNELTERCEFYTENCSLLERENESLKAVASAYRQL--QDIVTEKNIIISSLEVENRSLK 605
EM++L +R Y E LE +N L A A R +D +N+ L V+ + L
Sbjct: 89 EMSDLNDRLASYIEKVRFLEAQNRKLAADLDALRSKWGKDTHNIRNMYEGEL-VDAQKLI 147
Query: 606 KQVETKAKDLELLSVKHEREIAKL-KDLSKAERGRILKVWDRTDYEK---ALDSKEEEIV 661
+ + KD+E K + E+A++ + L A +GR DR + L + E EI
Sbjct: 148 DETNKQRKDMEGQLKKMQDELAEMRRKLEDATKGR---EQDRAKIDALLVTLSNLEAEIS 204
Query: 662 KLNHRISLLDLIIDNKVTEIKNNESRYRGLETKVAILSNENIVLKSKHDEVIKKKKEDLA 721
L RI+ L +++V IK R + ++ + + + ++ E++
Sbjct: 205 LLKRRIAQL----EDEVKRIKQENQRLLSELQRARTDLDQETLNRIDYQNQVQTLLEEID 260
Query: 722 FF-----NEKFQKRLLAMKREIDKNADMYHNELQSYRTNYEKTLSSALKVTLKAESALSA 776
F NE + + LA + +N + + NE LSSA++ + ++
Sbjct: 261 FLRRVHDNEIKELQTLASRDTTPENREFFKNE-----------LSSAIRDIREEYDQVNN 309
Query: 777 IYSNNVDRFGSTNRTLNYFMKKRDM-FQNIRDNMVSNKPKPEYKPAIT-ITSVSDGIENK 834
++ N+++ + Y +K +++ Q+ R NM K E K T ++ + + +
Sbjct: 310 VHRNDMESW--------YRLKVQEIQTQSARQNMEQGYAKEEVKRLRTQLSDLRGKLADL 361
Query: 835 DNRN-------EELHYISEQKQ-----GFNDSLRELKVANVNSNCSSRSKHNAKQIIQKL 882
++RN +EL+Y E Q ND R+ ++ + C + +Q L
Sbjct: 362 ESRNSLLEKQIQELNYQLEDDQRSYEAALND--RDSQIRKMREECQALMVE-----LQML 414
Query: 883 REWKQNQNTSELSPDKEDSIFSTGIETDYSTSNIAQL 919
+ KQ + D E +I+ +E + + + + QL
Sbjct: 415 LDTKQ-------TLDAEIAIYRKMLEGEENRAGLKQL 444
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.312 0.129 0.357
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 54,185,321
Number of Sequences: 60738
Number of extensions: 2359099
Number of successful extensions: 8498
Number of sequences better than 1.0e-05: 14
Number of HSP's better than 0.0 without gapping: 0
Number of HSP's successfully gapped in prelim test: 19
Number of HSP's that attempted gapping in prelim test: 8429
Number of HSP's gapped (non-prelim): 65
length of query: 940
length of database: 30,389,216
effective HSP length: 116
effective length of query: 824
effective length of database: 23,343,608
effective search space: 19235132992
effective search space used: 19235132992
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)