ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIV1255 good K KOG3712 Transcription RFX family transcription factor
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIV1255 417331 414875 -819
(819 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YLR176c [K] KOG3712 RFX family transcription factor 265 2e-70
SPAC3G9.14 [K] KOG3712 RFX family transcription factor 96 2e-19
Hs19743877 [K] KOG3712 RFX family transcription factor 69 3e-11
Hs19743881 [K] KOG3712 RFX family transcription factor 68 5e-11
Hs19743879 [K] KOG3712 RFX family transcription factor 68 5e-11
Hs4506495 [K] KOG3712 RFX family transcription factor 67 8e-11
Hs19743884 [K] KOG3712 RFX family transcription factor 67 8e-11
7299332 [K] KOG3712 RFX family transcription factor 67 8e-11
CE28019 [K] KOG3712 RFX family transcription factor 66 2e-10
CE17763 [K] KOG3712 RFX family transcription factor 66 2e-10
Hs15011898 [K] KOG3712 RFX family transcription factor 64 7e-10
Hs4557843 [K] KOG3712 RFX family transcription factor 60 1e-08
>YLR176c [K] KOG3712 RFX family transcription factor
Length = 811
Score = 265 bits (677), Expect = 2e-70
Identities = 198/620 (31%), Positives = 302/620 (47%), Gaps = 54/620 (8%)
Query: 231 KKQKVDEAMQPVRTGAAVTSKRTTQENILKLVAMKNKDKPLSEYASVVRNAEIQVLNMDT 290
KKQK + + + S+R TQE I K +A NK K + EYA +V++AEI+VL+MD+
Sbjct: 208 KKQKTSQEKR-----ISSISRRNTQEIIAKQIAENNKSKTIEEYAQIVKHAEIKVLSMDS 262
Query: 291 STHAKSEIQSAEQHRERERQVYALIWLMSNCVTDTESYVRRGRIFAQYAASCAQNQLKPL 350
+K+ +Q AEQ+RERERQV+AL+WLM NC + +SYV RG+IFAQYA+SC+QN LKPL
Sbjct: 263 QNTSKAALQLAEQNRERERQVFALLWLMKNCKSQHDSYVPRGKIFAQYASSCSQNNLKPL 322
Query: 351 SQATLGKLIRALFPFLKTRRLGMRGQSKYHYCGLKLVSPFATSSDLTPTGSS-----NSD 405
SQA+LGKLIR +FP L TRRLGMRGQSKYHYCGLKL + S L +S N+D
Sbjct: 323 SQASLGKLIRTVFPDLTTRRLGMRGQSKYHYCGLKLTVNESGSVSLNNNNASLSLVHNND 382
Query: 406 TSSAMLXXXXXX-------XXXXXXXXXXXLKYEGXXXXXXXXXXXXXNGIKSIQPNAML 458
S + L G ++S PN
Sbjct: 383 PISPLSSPSPSSPSPQVPNVSSPFSLNRKSLSRTGSPVKQSSNDNPNEPELESQHPNETE 442
Query: 459 GKQ-----SSVSDPLNQLSEDISLDVTGNIQGHDAGVKPVLSAETSFNTCYDEGYALLPD 513
+ + ++P LS D L T HD ++ V + + Y+ +
Sbjct: 443 ANKLDSLPPAANNPTGTLSSD-ELTFT-----HDL-IEKVFNCNDKLSDNYNTQILSNTE 495
Query: 514 FFAVTSEAKVELPIEFPDLQK-FLPVNQSVDPDIASSVNSLYQVYCNTLFENIRFMKFDD 572
+TS ++FP + LP + D D+ SS+ SLY ++CN+++E I+F+K D+
Sbjct: 496 HPLLTS-----YKLDFPKIPAGVLPTD--TDSDVISSLESLYHIHCNSVYECIKFLKSDN 548
Query: 573 LPLTLQXXXXXXXXXKMYNLFISEELYRWVHQSDLLTHKALTKMLSSLIVDFNEIPEVVF 632
+ L M+NLFISE L WV + DL+T+ L K S I+ NEI + +
Sbjct: 549 ISNALFFSNSNSISPTMFNLFISEPLIDWVTKCDLITYTGLIKFFSQFIIHSNEISDSII 608
Query: 633 NKLSDFSNEYMKMVEQSTMDLPLPMVTFKKSVAQAFCRLVKRLVKVIDNSKKLSNIMSKQ 692
KL + + ++ ++LP +V K S+ F +LVK+L+K++ L+ + S
Sbjct: 609 QKLESMIKLLPEQINKAVLELPKALVQRKLSIINNFTKLVKKLIKLL--KFILNFLKSFP 666
Query: 693 ENRLSMLYVWEQNVKVSE----LINQEFSYFNHPALEKDMQ---ELFSVQLLELLKKTDE 745
+ M W+ V + + +IN++ + + + +Q ++F + L
Sbjct: 667 IFKSGMNNDWKNIVNLDDILEMMINEDDTNSETNTIMQHLQGFCQVFVTKFLNSSMSVSN 726
Query: 746 D----FDLISFVKMVFGVLSNKSLPPRL----LVLTFNSFTAACTKEILTNSNENFGLWW 797
D + S +M+ S SL + L+ F A +I SNEN W
Sbjct: 727 DPSVSIECKSLNEMIKDFCSFISLQSKFSCLKLIDCSTRFRNAIIGDISLKSNENLLSWL 786
Query: 798 MFKAFLDEWIFWYAEVGGFL 817
+ + + + EV F+
Sbjct: 787 FLNNVMGQLLNYCFEVMKFV 806
>SPAC3G9.14 [K] KOG3712 RFX family transcription factor
Length = 766
Score = 95.9 bits (237), Expect = 2e-19
Identities = 43/92 (46%), Positives = 59/92 (63%)
Query: 295 KSEIQSAEQHRERERQVYALIWLMSNCVTDTESYVRRGRIFAQYAASCAQNQLKPLSQAT 354
K + + E+ RQV+ + WL C ++ V+R +I+A Y C +KPL+ A+
Sbjct: 83 KLRMDHVSANSEKFRQVFGICWLKRACEEQQDAAVQRNQIYAHYVEICNSLHIKPLNSAS 142
Query: 355 LGKLIRALFPFLKTRRLGMRGQSKYHYCGLKL 386
GKL+R LFP +KTRRLGMRG SKYHYCG+KL
Sbjct: 143 FGKLVRLLFPSIKTRRLGMRGHSKYHYCGIKL 174
Score = 81.3 bits (199), Expect = 6e-15
Identities = 63/295 (21%), Positives = 127/295 (42%), Gaps = 27/295 (9%)
Query: 548 SSVNSLYQVYCNTLFENIRFMKFDDLPLTLQXXXXXXXXXKMYNLFISEELYRWVHQSDL 607
S++ ++Y +C TL E++R+M L+ + L S +W+ +SD
Sbjct: 391 SALMNIYSSHCITLIESVRYMHLKQF-LSEISNFPNSLSPSLLALLSSPYFTKWIERSDT 449
Query: 608 LTHKALTKMLSSLIVDFNEIPEVVFNKLSDFSNEYMKMVEQSTMDLPLPMVTFKKSVAQA 667
+ ++ + K+L + + +P V L + + + ++ K A
Sbjct: 450 VMYREILKLLFPMTLQV--VPPPVLVLLRHLAENLVNHISSIYASHSSCLLQVKSETAAI 507
Query: 668 FCRLVKRLVKVIDNSKKLSNIMSKQENRLSMLYVWEQNVKVSELINQEFSYFNHPALEKD 727
F L+ RL++V D + + ++ +R + WE+ V ++++E + A+
Sbjct: 508 FSNLLSRLLRVNDTAHAAARFLANPADRHLICNDWERFVSTRFIVHRELMCNDKEAVAA- 566
Query: 728 MQELFSV--------QLLELLKKTDEDFDLISF---VKMVFGVLSNK------------S 764
+ E +S+ +LL+ LK E D ++ + GVL S
Sbjct: 567 LDEWYSILSTCSNPSELLDPLKDKHEASDTSMNRVELRQIDGVLDRMADFFLELPSRFPS 626
Query: 765 LPPRLLVLTFNSFTAACTKEILTNSNENFGLWWMFKAFLDEWIFWYAEVGGFLKD 819
PR+ +L + + +EI + E FG W+ + ++DE++ W AE+GG+L D
Sbjct: 627 CSPRMFLLCLGALQTSVLREITVSGGEAFGALWVIRCWVDEYMTWVAEIGGYLDD 681
>Hs19743877 [K] KOG3712 RFX family transcription factor
Length = 979
Score = 68.9 bits (167), Expect = 3e-11
Identities = 31/71 (43%), Positives = 46/71 (64%)
Query: 316 WLMSNCVTDTESYVRRGRIFAQYAASCAQNQLKPLSQATLGKLIRALFPFLKTRRLGMRG 375
WL+ N T + R ++ Y C + +L+P++ A+ GKLIR++F L+TRRLG RG
Sbjct: 441 WLLDNYETAEGVSLPRSTLYCHYLLHCQEQKLEPVNAASFGKLIRSVFMGLRTRRLGTRG 500
Query: 376 QSKYHYCGLKL 386
SKYHY GL++
Sbjct: 501 NSKYHYYGLRI 511
>Hs19743881 [K] KOG3712 RFX family transcription factor
Length = 723
Score = 68.2 bits (165), Expect = 5e-11
Identities = 32/73 (43%), Positives = 47/73 (63%)
Query: 314 LIWLMSNCVTDTESYVRRGRIFAQYAASCAQNQLKPLSQATLGKLIRALFPFLKTRRLGM 373
L WL+ N T + R ++ Y C +++L P++ A+ GKLIR++F L+TRRLG
Sbjct: 200 LQWLLDNYETAEGVSLPRSSLYNHYLRHCQEHKLDPVNAASFGKLIRSVFMGLRTRRLGT 259
Query: 374 RGQSKYHYCGLKL 386
RG SKYHY G++L
Sbjct: 260 RGNSKYHYYGIRL 272
>Hs19743879 [K] KOG3712 RFX family transcription factor
Length = 698
Score = 68.2 bits (165), Expect = 5e-11
Identities = 32/73 (43%), Positives = 47/73 (63%)
Query: 314 LIWLMSNCVTDTESYVRRGRIFAQYAASCAQNQLKPLSQATLGKLIRALFPFLKTRRLGM 373
L WL+ N T + R ++ Y C +++L P++ A+ GKLIR++F L+TRRLG
Sbjct: 175 LQWLLDNYETAEGVSLPRSSLYNHYLRHCQEHKLDPVNAASFGKLIRSVFMGLRTRRLGT 234
Query: 374 RGQSKYHYCGLKL 386
RG SKYHY G++L
Sbjct: 235 RGNSKYHYYGIRL 247
>Hs4506495 [K] KOG3712 RFX family transcription factor
Length = 707
Score = 67.4 bits (163), Expect = 8e-11
Identities = 31/73 (42%), Positives = 47/73 (63%)
Query: 314 LIWLMSNCVTDTESYVRRGRIFAQYAASCAQNQLKPLSQATLGKLIRALFPFLKTRRLGM 373
L WL+ N T + R ++ Y C +++L P++ A+ GKLIR++F L+TRRLG
Sbjct: 184 LQWLLDNYETAEGVSLPRSTLYNHYLRHCQEHKLDPVNAASFGKLIRSIFMGLRTRRLGT 243
Query: 374 RGQSKYHYCGLKL 386
RG SKYHY G+++
Sbjct: 244 RGNSKYHYYGIRV 256
>Hs19743884 [K] KOG3712 RFX family transcription factor
Length = 749
Score = 67.4 bits (163), Expect = 8e-11
Identities = 31/73 (42%), Positives = 47/73 (63%)
Query: 314 LIWLMSNCVTDTESYVRRGRIFAQYAASCAQNQLKPLSQATLGKLIRALFPFLKTRRLGM 373
L WL+ N T + R ++ Y C +++L P++ A+ GKLIR++F L+TRRLG
Sbjct: 184 LQWLLDNYETAEGVSLPRSTLYNHYLRHCQEHKLDPVNAASFGKLIRSIFMGLRTRRLGT 243
Query: 374 RGQSKYHYCGLKL 386
RG SKYHY G+++
Sbjct: 244 RGNSKYHYYGIRV 256
>7299332 [K] KOG3712 RFX family transcription factor
Length = 901
Score = 67.4 bits (163), Expect = 8e-11
Identities = 30/71 (42%), Positives = 47/71 (65%)
Query: 316 WLMSNCVTDTESYVRRGRIFAQYAASCAQNQLKPLSQATLGKLIRALFPFLKTRRLGMRG 375
WL N T + R ++ Y C++++L+P++ A+ GKLIR++F L+TRRLG RG
Sbjct: 378 WLSRNYETADGVSLPRSTLYNHYMQHCSEHKLEPVNAASFGKLIRSVFSGLRTRRLGTRG 437
Query: 376 QSKYHYCGLKL 386
SKYHY G+++
Sbjct: 438 NSKYHYYGIRI 448
>CE28019 [K] KOG3712 RFX family transcription factor
Length = 805
Score = 65.9 bits (159), Expect = 2e-10
Identities = 32/71 (45%), Positives = 46/71 (64%), Gaps = 1/71 (1%)
Query: 316 WLMSNCVTDTESYVRRGRIFAQYAASCAQNQLKPLSQATLGKLIRALFPFLKTRRLGMRG 375
WL N E + R ++ Y CA++++ P++ A+ GKLIR++F LKTRRLG RG
Sbjct: 263 WLFENYEIG-EGSLPRCELYDHYKKHCAEHRMDPVNAASFGKLIRSVFHNLKTRRLGTRG 321
Query: 376 QSKYHYCGLKL 386
SKYHY G++L
Sbjct: 322 NSKYHYYGIRL 332
>CE17763 [K] KOG3712 RFX family transcription factor
Length = 780
Score = 65.9 bits (159), Expect = 2e-10
Identities = 32/71 (45%), Positives = 46/71 (64%), Gaps = 1/71 (1%)
Query: 316 WLMSNCVTDTESYVRRGRIFAQYAASCAQNQLKPLSQATLGKLIRALFPFLKTRRLGMRG 375
WL N E + R ++ Y CA++++ P++ A+ GKLIR++F LKTRRLG RG
Sbjct: 238 WLFENYEIG-EGSLPRCELYDHYKKHCAEHRMDPVNAASFGKLIRSVFHNLKTRRLGTRG 296
Query: 376 QSKYHYCGLKL 386
SKYHY G++L
Sbjct: 297 NSKYHYYGIRL 307
>Hs15011898 [K] KOG3712 RFX family transcription factor
Length = 563
Score = 64.3 bits (155), Expect = 7e-10
Identities = 36/99 (36%), Positives = 52/99 (52%), Gaps = 4/99 (4%)
Query: 290 TSTHAKSEIQSAEQHRERERQVYA----LIWLMSNCVTDTESYVRRGRIFAQYAASCAQN 345
TS S ++ E+ R + ++ L WL N + R ++ Y C +N
Sbjct: 43 TSLGNVSNDENEEKENNRASKPHSTPATLQWLEENYEIAEGVCIPRSALYMHYLDFCEKN 102
Query: 346 QLKPLSQATLGKLIRALFPFLKTRRLGMRGQSKYHYCGL 384
+P++ A+ GK+IR FP L TRRLG RGQSKYHY G+
Sbjct: 103 DTQPVNAASFGKIIRQQFPQLTTRRLGTRGQSKYHYYGI 141
>Hs4557843 [K] KOG3712 RFX family transcription factor
Length = 616
Score = 60.1 bits (144), Expect = 1e-08
Identities = 30/79 (37%), Positives = 46/79 (57%), Gaps = 1/79 (1%)
Query: 308 ERQVYALIWLMSNCVTDTESYVRRGRIFAQYAASCAQNQL-KPLSQATLGKLIRALFPFL 366
E +YA W+ ++ T++ + + ++ Y C +PLS A GK+IR +FP +
Sbjct: 87 EEYMYAYRWIRNHLEEHTDTCLPKQSVYDAYRKYCESLACCRPLSTANFGKIIREIFPDI 146
Query: 367 KTRRLGMRGQSKYHYCGLK 385
K RRLG RGQSKY Y G++
Sbjct: 147 KARRLGGRGQSKYCYSGIR 165
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.319 0.132 0.383
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 38,195,062
Number of Sequences: 60738
Number of extensions: 1366289
Number of successful extensions: 3808
Number of sequences better than 1.0e-05: 12
Number of HSP's better than 0.0 without gapping: 12
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 3783
Number of HSP's gapped (non-prelim): 21
length of query: 819
length of database: 30,389,216
effective HSP length: 115
effective length of query: 704
effective length of database: 23,404,346
effective search space: 16476659584
effective search space used: 16476659584
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)