ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIV1419 good Q KOG0024 Secondary metabolites biosynthesis, transport and catabolism Sorbitol dehydrogenase
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIV1419 477427 476366 -354
(354 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YJR159w [Q] KOG0024 Sorbitol dehydrogenase 414 e-116
YDL246c [Q] KOG0024 Sorbitol dehydrogenase 414 e-115
YLR070c [Q] KOG0024 Sorbitol dehydrogenase 333 3e-91
SPBC1773.05c [Q] KOG0024 Sorbitol dehydrogenase 271 8e-73
7299382 [Q] KOG0024 Sorbitol dehydrogenase 270 3e-72
7298873 [Q] KOG0024 Sorbitol dehydrogenase 270 3e-72
CE06215 [Q] KOG0024 Sorbitol dehydrogenase 241 2e-63
Hs4507155 [Q] KOG0024 Sorbitol dehydrogenase 224 1e-58
CE06216 [Q] KOG0024 Sorbitol dehydrogenase 223 3e-58
At5g51970 [Q] KOG0024 Sorbitol dehydrogenase 202 6e-52
Hs20549232 [Q] KOG0024 Sorbitol dehydrogenase 154 2e-37
Hs18583841 [Q] KOG0024 Sorbitol dehydrogenase 153 4e-37
YAL061w [Q] KOG0024 Sorbitol dehydrogenase 104 2e-22
YAL060w [Q] KOG0024 Sorbitol dehydrogenase 103 3e-22
7300579 [Q] KOG0024 Sorbitol dehydrogenase 92 9e-19
At5g63620 [Q] KOG0022 Alcohol dehydrogenase class III 77 4e-14
YMR083w [Q] KOG0023 Alcohol dehydrogenase class V 61 2e-09
SPBC1198.01 [Q] KOG0024 Sorbitol dehydrogenase 61 3e-09
CE20628 [Q] KOG0023 Alcohol dehydrogenase class V 60 5e-09
At1g22430 [Q] KOG0022 Alcohol dehydrogenase class III 59 8e-09
YOL086c [Q] KOG0023 Alcohol dehydrogenase class V 57 5e-08
SPCC13B11.01 [Q] KOG0023 Alcohol dehydrogenase class V 55 2e-07
Hs4501935 [Q] KOG0022 Alcohol dehydrogenase class III 54 5e-07
At4g22110 [Q] KOG0022 Alcohol dehydrogenase class III 53 6e-07
YBR145w [Q] KOG0023 Alcohol dehydrogenase class V 53 8e-07
At5g42250 [Q] KOG0022 Alcohol dehydrogenase class III 52 1e-06
YMR303c [Q] KOG0023 Alcohol dehydrogenase class V 52 2e-06
>YJR159w [Q] KOG0024 Sorbitol dehydrogenase
Length = 357
Score = 414 bits (1065), Expect = e-116
Identities = 200/350 (57%), Positives = 249/350 (71%), Gaps = 2/350 (0%)
Query: 7 AVVLQKKGEITFEDIPAPEITDSHYVKIHVKKTGICGSDIHYYTHGSIGEFVVKKPMVLG 66
AVVL+K G+I E P P I D HYVK+ +K TGICGSDIHYY G IG++++K PMVLG
Sbjct: 8 AVVLEKVGDIAIEQRPIPTIKDPHYVKLAIKATGICGSDIHYYRSGGIGKYILKAPMVLG 67
Query: 67 HXXXXXXXXXXKDVTLVQVGDRVAIEPGVPSRYSDETKSGHYNLCPHMAFAATPPYDGTL 126
H VT V+VGDRVAIEPGVPSRYSDETK G YNLCPHMAFAATPP DGTL
Sbjct: 68 HESSGQVVEVGDAVTRVKVGDRVAIEPGVPSRYSDETKEGRYNLCPHMAFAATPPIDGTL 127
Query: 127 VKYYLAPEDFLVKLPDHVSFEEGACAEPLAVGVHANRLAETSFGKNVVVFXXXXXXXXXX 186
VKYYL+PEDFLVKLP+ VS+EEGAC EPL+VGVH+N+LA FG VVVF
Sbjct: 128 VKYYLSPEDFLVKLPEGVSYEEGACVEPLSVGVHSNKLAGVRFGTKVVVFGAGPVGLLTG 187
Query: 187 XXXXXXXXXXXXXXDVFENKLERSKDFGATNTINSTKYKSE--DELTEVIKSELKGEQPE 244
DVF+NKL+R+KDFGATNT NS+++ ++ +L + ++ L G +
Sbjct: 188 AVARAFGATDVIFVDVFDNKLQRAKDFGATNTFNSSQFSTDKAQDLADGVQKLLGGNHAD 247
Query: 245 IAIDCSGAEICIRTAIKVLKAGGSYVQVGMGKDNINFPIAMIGAKELRVLGSFRYYFNDY 304
+ +CSGA++CI A+K K GG+ VQVGMGK+ NFPIA + KE++++G FRY F DY
Sbjct: 248 VVFECSGADVCIDAAVKTTKVGGTMVQVGMGKNYTNFPIAEVSGKEMKLIGCFRYSFGDY 307
Query: 305 KIAVKLISEGKVNVKKMITHTFKFEEAIDAYNFNLEHGSEVVKTMIDGPE 354
+ AV L++ GKVNVK +ITH FKFE+A AY++N+ HG EVVKT+I GPE
Sbjct: 308 RDAVNLVATGKVNVKPLITHKFKFEDAAKAYDYNIAHGGEVVKTIIFGPE 357
>YDL246c [Q] KOG0024 Sorbitol dehydrogenase
Length = 357
Score = 414 bits (1064), Expect = e-115
Identities = 200/350 (57%), Positives = 249/350 (71%), Gaps = 2/350 (0%)
Query: 7 AVVLQKKGEITFEDIPAPEITDSHYVKIHVKKTGICGSDIHYYTHGSIGEFVVKKPMVLG 66
AVVL+K G+I E P P I D HYVK+ +K TGICGSDIHYY G IG++++K PMVLG
Sbjct: 8 AVVLEKVGDIAIEQRPIPTIKDPHYVKLAIKATGICGSDIHYYRSGGIGKYILKAPMVLG 67
Query: 67 HXXXXXXXXXXKDVTLVQVGDRVAIEPGVPSRYSDETKSGHYNLCPHMAFAATPPYDGTL 126
H VT V+VGDRVAIEPGVPSRYSDETK G YNLCPHMAFAATPP DGTL
Sbjct: 68 HESSGQVVEVGDAVTRVKVGDRVAIEPGVPSRYSDETKEGSYNLCPHMAFAATPPIDGTL 127
Query: 127 VKYYLAPEDFLVKLPDHVSFEEGACAEPLAVGVHANRLAETSFGKNVVVFXXXXXXXXXX 186
VKYYL+PEDFLVKLP+ VS+EEGAC EPL+VGVH+N+LA FG VVVF
Sbjct: 128 VKYYLSPEDFLVKLPEGVSYEEGACVEPLSVGVHSNKLAGVRFGTKVVVFGAGPVGLLTG 187
Query: 187 XXXXXXXXXXXXXXDVFENKLERSKDFGATNTINSTKYKSE--DELTEVIKSELKGEQPE 244
DVF+NKL+R+KDFGATNT NS+++ ++ +L + ++ L G +
Sbjct: 188 AVARAFGATDVIFVDVFDNKLQRAKDFGATNTFNSSQFSTDKAQDLADGVQKLLGGNHAD 247
Query: 245 IAIDCSGAEICIRTAIKVLKAGGSYVQVGMGKDNINFPIAMIGAKELRVLGSFRYYFNDY 304
+ +CSGA++CI A+K K GG+ VQVGMGK+ NFPIA + KE++++G FRY F DY
Sbjct: 248 VVFECSGADVCIDAAVKTTKVGGTMVQVGMGKNYTNFPIAEVSGKEMKLIGCFRYSFGDY 307
Query: 305 KIAVKLISEGKVNVKKMITHTFKFEEAIDAYNFNLEHGSEVVKTMIDGPE 354
+ AV L++ GKVNVK +ITH FKFE+A AY++N+ HG EVVKT+I GPE
Sbjct: 308 RDAVNLVATGKVNVKPLITHKFKFEDAAKAYDYNIAHGGEVVKTIIFGPE 357
>YLR070c [Q] KOG0024 Sorbitol dehydrogenase
Length = 356
Score = 333 bits (853), Expect = 3e-91
Identities = 162/351 (46%), Positives = 225/351 (63%)
Query: 4 TQKAVVLQKKGEITFEDIPAPEITDSHYVKIHVKKTGICGSDIHYYTHGSIGEFVVKKPM 63
TQ+A+VL++ G+IT ++ P+I+D + V I +K TGICGSDIHYYTHG I +VV+ PM
Sbjct: 6 TQEAIVLERPGKITLTNVSIPKISDPNEVIIQIKATGICGSDIHYYTHGRIANYVVESPM 65
Query: 64 VLGHXXXXXXXXXXKDVTLVQVGDRVAIEPGVPSRYSDETKSGHYNLCPHMAFAATPPYD 123
VLGH ++V ++VGDRVA+EPG+P R+S E K G YNL P++ FAATPP+D
Sbjct: 66 VLGHESSGIVALIGENVKTLKVGDRVALEPGIPDRFSPEMKEGRYNLDPNLKFAATPPFD 125
Query: 124 GTLVKYYLAPEDFLVKLPDHVSFEEGACAEPLAVGVHANRLAETSFGKNVVVFXXXXXXX 183
GTL KYY +DF+ KLPD VSFEEGA EPL+V +HAN+LA+ FG VVF
Sbjct: 126 GTLTKYYKTMKDFVYKLPDDVSFEEGALIEPLSVAIHANKLAKIKFGARCVVFGAGPIGL 185
Query: 184 XXXXXXXXXXXXXXXXXDVFENKLERSKDFGATNTINSTKYKSEDELTEVIKSELKGEQP 243
D+ ENKLE ++ FGAT+ +NS + VIK + +
Sbjct: 186 LAGKVASVFGAADVVFVDLLENKLETARQFGATHIVNSGDLPHGVTVDSVIKKAIGKKGA 245
Query: 244 EIAIDCSGAEICIRTAIKVLKAGGSYVQVGMGKDNINFPIAMIGAKELRVLGSFRYYFND 303
++ +CSGAE C+R I+V KAGG+ VQVGMG++ I FPI++I KEL G FRY D
Sbjct: 246 DVVFECSGAEPCVRAGIEVCKAGGTIVQVGMGQEEIQFPISIIPTKELTFQGCFRYCQGD 305
Query: 304 YKIAVKLISEGKVNVKKMITHTFKFEEAIDAYNFNLEHGSEVVKTMIDGPE 354
Y +++L+S K+++K ITH + F++A++A+ H +KT+I+GPE
Sbjct: 306 YSDSIELVSSRKLSLKPFITHRYSFKDAVEAFEETSHHPLNNIKTIIEGPE 356
>SPBC1773.05c [Q] KOG0024 Sorbitol dehydrogenase
Length = 360
Score = 271 bits (694), Expect = 8e-73
Identities = 147/360 (40%), Positives = 198/360 (54%), Gaps = 7/360 (1%)
Query: 1 MSGTQKAVVLQKKGEITFEDIPAPEITDSHYVKIHVKKTGICGSDIHYYTHGSIGEFVVK 60
M+ +KA VL+KK + ED P +TD H VK+ +K TGICGSD+HY+ G IG+F++K
Sbjct: 1 MAPAEKAFVLRKKMDTAIEDRPGQTLTDDHQVKVAIKATGICGSDVHYWKEGGIGDFILK 60
Query: 61 KPMVLGHXXXXXXXXXXKDVTLVQVGDRVAIEPGVPSRYSDETKSGHYNLCPHMAFAATP 120
KPM+LGH K V+ ++ GD VA+EPG R D +SG YNLCPHM FAATP
Sbjct: 61 KPMILGHESAGVVVEVGKGVSSLKPGDPVAVEPGCVCRLCDYCRSGRYNLCPHMEFAATP 120
Query: 121 PYDGTLVKYYLAPEDFLVKLPDHVSFEEGACAEPLAVGVHANRLAETSFGKNVVVFXXXX 180
PYDGTL YY+ EDF KLP +S EEGA EP++V VHA G V+V
Sbjct: 121 PYDGTLRTYYITTEDFCTKLPKQISVEEGALFEPMSVAVHAMTRGNLKCGSRVLVMGCGT 180
Query: 181 XXXXXXXXXXXXXXXXXXXXDVFENKLERSKDFGATNTINSTKYKSEDELTEVIKS---- 236
D +++E ++ + K + L + +
Sbjct: 181 VGLLMMAVAKAYGAIDIVAVDASPSRVEFAQKYVGAKPFTPIAAKENESLPDYAQRYKQA 240
Query: 237 --ELKGEQPEIAIDCSGAEICIRTAIKVLKAGGSYVQVGMGKDNINFPIAMIGAKELRVL 294
E GE + A+D +G ICI TA+ LK GG++VQ G GK I+FPI I E+ VL
Sbjct: 241 IIEKYGEF-DFAVDATGVGICIHTAVLALKRGGTFVQAGNGKPVIDFPINHIINYEINVL 299
Query: 295 GSFRYYFNDYKIAVKLISEGKVNVKKMITHTFKFEEAIDAYNFNLEHGSEVVKTMIDGPE 354
GSFRY YK ++ L+S G V+VK +ITH F F++A+ AY V+K +I GP+
Sbjct: 300 GSFRYAHGCYKQSLFLVSNGLVDVKPLITHRFAFKDALKAYETVASGEEGVLKVIIGGPD 359
>7299382 [Q] KOG0024 Sorbitol dehydrogenase
Length = 360
Score = 270 bits (689), Expect = 3e-72
Identities = 143/350 (40%), Positives = 193/350 (54%), Gaps = 3/350 (0%)
Query: 1 MSGTQKAVVLQKKGEITFEDIPAPEITDSHYVKIHVKKTGICGSDIHYYTHGSIGEFVVK 60
M+ VL ++ E P PEI D V + + GICGSD+HY HG IG+FV+
Sbjct: 1 MATDNLTAVLHGIEDLRLEQRPIPEIADDE-VLLAMDSVGICGSDVHYLAHGRIGDFVLT 59
Query: 61 KPMVLGHXXXXXXXXXXKDVTLVQVGDRVAIEPGVPSRYSDETKSGHYNLCPHMAFAATP 120
KPM++GH K VT ++VGDRVAIEPGVP RY D K G YNLC M F ATP
Sbjct: 60 KPMIIGHEAAGVVAKLGKKVTTLKVGDRVAIEPGVPCRYCDHCKQGRYNLCADMVFCATP 119
Query: 121 PYDGTLVKYYLAPEDFLVKLPDHVSFEEGACAEPLAVGVHANRLAETSFGKNVVVFXXXX 180
PYDG L +YY DF KLPDHVS EEGA EPL+VGVHA R A G V++
Sbjct: 120 PYDGNLTRYYKHAADFCFKLPDHVSMEEGALLEPLSVGVHACRRAGVGLGSKVLILGAGP 179
Query: 181 XXXXXXXXXXXXXXXXXXXXDVFENKLERSKDFGATNTINSTKYKSEDELTEVIKSELKG 240
D+ + +L+ +K+ GAT+T+ + +S +E +V+ +
Sbjct: 180 IGLVTLLAAQAMGASEILITDLVQQRLDVAKELGATHTLLLQRDQSAEETVKVVHQTM-S 238
Query: 241 EQPEIAIDCSGAEICIRTAIKVLKAGGSYVQVGMGKDNINFPIAMIGAKELRVLGSFRYY 300
E P+ +IDC GAE R AI ++GG V VGMG + P+ A+E+ + G FR Y
Sbjct: 239 EVPDKSIDCCGAESSARLAIFATRSGGVVVVVGMGAPEVKLPLINALAREIDIRGVFR-Y 297
Query: 301 FNDYKIAVKLISEGKVNVKKMITHTFKFEEAIDAYNFNLEHGSEVVKTMI 350
NDY A+ L++ GKVNVK+++TH + E +A+ + +K MI
Sbjct: 298 CNDYSAALALVASGKVNVKRLVTHHYDITETAEAFETSRRGTGGAIKVMI 347
>7298873 [Q] KOG0024 Sorbitol dehydrogenase
Length = 360
Score = 270 bits (689), Expect = 3e-72
Identities = 145/350 (41%), Positives = 197/350 (55%), Gaps = 3/350 (0%)
Query: 1 MSGTQKAVVLQKKGEITFEDIPAPEITDSHYVKIHVKKTGICGSDIHYYTHGSIGEFVVK 60
M+ VL ++ E P PEI D V + + GICGSD+HY HG IG+FV+
Sbjct: 1 MAKDNLTAVLHGIEDMRLEQRPIPEIADDE-VLLAMDSVGICGSDVHYLAHGRIGDFVLT 59
Query: 61 KPMVLGHXXXXXXXXXXKDVTLVQVGDRVAIEPGVPSRYSDETKSGHYNLCPHMAFAATP 120
KPM++GH K VT ++VGDRVAIEPGVP R D K G YNLCP M F ATP
Sbjct: 60 KPMIIGHESAGVVAKLGKKVTTLKVGDRVAIEPGVPCRKCDHCKQGKYNLCPGMVFCATP 119
Query: 121 PYDGTLVKYYLAPEDFLVKLPDHVSFEEGACAEPLAVGVHANRLAETSFGKNVVVFXXXX 180
PYDG L +YY DF KLPDHV+ EEGA EPL+VGVHA + AE + G V++
Sbjct: 120 PYDGNLTRYYKHAADFCFKLPDHVTMEEGALLEPLSVGVHACKRAEVTLGSKVLILGAGP 179
Query: 181 XXXXXXXXXXXXXXXXXXXXDVFENKLERSKDFGATNTINSTKYKSEDELTEVIKSELKG 240
D+ + +L+ +K+ GAT+T+ + ++ +E T V+ + G
Sbjct: 180 IGLVTLMAAQAMGASEILITDLVQQRLDVAKELGATHTLLLKRDQTAEE-TAVLVQKTMG 238
Query: 241 EQPEIAIDCSGAEICIRTAIKVLKAGGSYVQVGMGKDNINFPIAMIGAKELRVLGSFRYY 300
QP+ +IDC GAE R AI ++GG V VGMG I P+ A+E+ + G FR Y
Sbjct: 239 GQPDKSIDCCGAESSARLAIFATRSGGIVVVVGMGAAEIKLPLINALAREVDIRGVFR-Y 297
Query: 301 FNDYKIAVKLISEGKVNVKKMITHTFKFEEAIDAYNFNLEHGSEVVKTMI 350
NDY A+ L++ GKVNVK+++TH F +E A+ + + +K MI
Sbjct: 298 CNDYAAALALVASGKVNVKRLVTHHFDIKETAKAFETSRKGLGGAIKVMI 347
>CE06215 [Q] KOG0024 Sorbitol dehydrogenase
Length = 347
Score = 241 bits (614), Expect = 2e-63
Identities = 133/350 (38%), Positives = 192/350 (54%), Gaps = 5/350 (1%)
Query: 1 MSGTQKAVVLQKKGEITFEDIPAPEITDSHYVKIHVKKTGICGSDIHYYTHGSIGEFVVK 60
MS + VL ++ E +P P+ + V + V GICGSD+HY+THG+IG FVVK
Sbjct: 1 MSQDNLSAVLYGVDDLRLEQVPIPK-PGPNQVLVKVHTVGICGSDVHYWTHGAIGPFVVK 59
Query: 61 KPMVLGHXXXXXXXXXXKDVTLVQVGDRVAIEPGVPSRYSDETKSGHYNLCPHMAFAATP 120
+PM++GH +V ++VGDR+A+EPG+P + + K+G YNLCP M F ATP
Sbjct: 60 EPMIVGHETSGIVSEVGNEVKHLKVGDRIAMEPGLPCKLCEHCKTGRYNLCPEMRFFATP 119
Query: 121 PYDGTLVKYYLAPEDFLVKLPDHVSFEEGACAEPLAVGVHANRLAETSFGKNVVVFXXXX 180
P GTL ++ + DF KLPD++SFE+GA EPL+V +HA R G V+V
Sbjct: 120 PVHGTLSRFVVHDADFCFKLPDNLSFEDGALIEPLSVAIHACRRGNVQMGHRVLVLGAGP 179
Query: 181 XXXXXXXXXXXXXXXXXXXXDVFENKLERSKDFGATNTINSTKYKSEDELTEVIKSELKG 240
D+ + +L +K GA TIN K KS D + I + L
Sbjct: 180 IGVLNLITAKAVGAGKVVITDLDDGRLALAKKLGADATIN-VKGKSLDAVKSEIITALGD 238
Query: 241 EQPEIAIDCSGAEICIRTAIKVLKAGGSYVQVGMGKDNINFPIAMIGAKELRVLGSFRYY 300
+QP++ I+C+GA+ I TAI K+GG V VG+G D + PI +E+ + G FR Y
Sbjct: 239 QQPDVCIECTGAQPSIETAITTTKSGGVIVLVGLGADRVEIPIIESATREVDMRGIFR-Y 297
Query: 301 FNDYKIAVKLISEGKVNVKKMITHTFKFEEAIDAYNFNLEHGSEVVKTMI 350
N Y A++LIS GK+N+ + +K EE +A F ++V+K I
Sbjct: 298 VNCYPTAIELISSGKLNLSGLTRAHYKLEETQEA--FKRTQKADVIKVFI 345
>Hs4507155 [Q] KOG0024 Sorbitol dehydrogenase
Length = 357
Score = 224 bits (572), Expect = 1e-58
Identities = 119/329 (36%), Positives = 182/329 (55%), Gaps = 4/329 (1%)
Query: 7 AVVLQKKGEITFEDIPAPEITDSHYVKIHVKKTGICGSDIHYYTHGSIGEFVVKKPMVLG 66
++V+ G++ E+ P PE + V + + GICGSD+HY+ +G IG F+VKKPMVLG
Sbjct: 11 SLVVHGPGDLRLENYPIPE-PGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLG 69
Query: 67 HXXXXXXXXXXKDVTLVQVGDRVAIEPGVPSRYSDETKSGHYNLCPHMAFAATPPYDGTL 126
H V ++ GDRVAIEPG P + K G YNL P + F ATPP DG L
Sbjct: 70 HEASGTVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCATPPDDGNL 129
Query: 127 VKYYLAPEDFLVKLPDHVSFEEGACAEPLAVGVHANRLAETSFGKNVVVFXXXXXXXXXX 186
++Y F KLPD+V+FEEGA EPL+VG+HA R + G V+V
Sbjct: 130 CRFYKHNAAFCYKLPDNVTFEEGALIEPLSVGIHACRRGGVTLGHKVLVCGAGPIGMVTL 189
Query: 187 XXXXXXXXXXXXXXDVFENKLERSKDFGATNTINSTKYKSEDELTEVIKSELKGEQPEIA 246
D+ +L ++K+ GA + +K +S E+ ++ +L G +PE+
Sbjct: 190 LVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISK-ESPQEIARKVEGQL-GCKPEVT 247
Query: 247 IDCSGAEICIRTAIKVLKAGGSYVQVGMGKDNINFPIAMIGAKELRVLGSFRYYFNDYKI 306
I+C+GAE I+ I ++GG+ V VG+G + P+ +E+ + G FR Y N + +
Sbjct: 248 IECTGAEASIQAGIYATRSGGTLVLVGLGSEMTTVPLLHAAIREVDIKGVFR-YCNTWPV 306
Query: 307 AVKLISEGKVNVKKMITHTFKFEEAIDAY 335
A+ +++ VNVK ++TH F E+A++A+
Sbjct: 307 AISMLASKSVNVKPLVTHRFPLEKALEAF 335
>CE06216 [Q] KOG0024 Sorbitol dehydrogenase
Length = 347
Score = 223 bits (569), Expect = 3e-58
Identities = 120/350 (34%), Positives = 189/350 (53%), Gaps = 5/350 (1%)
Query: 1 MSGTQKAVVLQKKGEITFEDIPAPEITDSHYVKIHVKKTGICGSDIHYYTHGSIGEFVVK 60
MS + VL ++ E P + V + + GICGSD+H+ THG+IG FVVK
Sbjct: 1 MSQDNLSAVLYGINDLRLEQAPISK-PGPRQVLVKINTVGICGSDVHFLTHGAIGSFVVK 59
Query: 61 KPMVLGHXXXXXXXXXXKDVTLVQVGDRVAIEPGVPSRYSDETKSGHYNLCPHMAFAATP 120
+PMVLGH +V +VGDR+A+EPG+P + + K G YNLCP M F ATP
Sbjct: 60 EPMVLGHESSGVVSEIGSEVKGFKVGDRIAMEPGLPCKLCEHCKIGRYNLCPDMRFFATP 119
Query: 121 PYDGTLVKYYLAPEDFLVKLPDHVSFEEGACAEPLAVGVHANRLAETSFGKNVVVFXXXX 180
P +G L ++ + DF KLPD++SFE+GA EPL+V + A R G+ ++V
Sbjct: 120 PVNGALSRFVVHDADFCFKLPDNLSFEDGALLEPLSVAIQACRRGTVQMGQKILVLGAGP 179
Query: 181 XXXXXXXXXXXXXXXXXXXXDVFENKLERSKDFGATNTINSTKYKSEDELTEVIKSELKG 240
D+ + +L ++ GA TIN +S++ +E+IK+
Sbjct: 180 IGVLNLLTAKAIGASKVVITDLNDERLALARLLGADATINVMGKRSDEVRSEIIKA-FGD 238
Query: 241 EQPEIAIDCSGAEICIRTAIKVLKAGGSYVQVGMGKDNINFPIAMIGAKELRVLGSFRYY 300
+QP ++I+C+G + C+ TAI ++GG V VG+G + + P+ +E+ + G+FR
Sbjct: 239 QQPHVSIECTGVQPCVETAIMTTRSGGVVVLVGLGAERVEIPLIQSPTREVDLRGTFR-S 297
Query: 301 FNDYKIAVKLISEGKVNVKKMITHTFKFEEAIDAYNFNLEHGSEVVKTMI 350
N Y A++LIS GK+++ + +K EE+++A F +V+K I
Sbjct: 298 ANCYSTAIELISSGKLDLSGLTRAHYKLEESLEA--FKRTQNGDVIKVFI 345
>At5g51970 [Q] KOG0024 Sorbitol dehydrogenase
Length = 364
Score = 202 bits (514), Expect = 6e-52
Identities = 119/325 (36%), Positives = 170/325 (51%), Gaps = 6/325 (1%)
Query: 30 HYVKIHVKKTGICGSDIHYYTHGSIGEFVVKKPMVLGHXXXXXXXXXXKDVTLVQVGDRV 89
H V++ +K GICGSD+HY +FVVK+PMV+GH ++V + VGDRV
Sbjct: 42 HDVRVRMKAVGICGSDVHYLKTMRCADFVVKEPMVIGHECAGIIEEVGEEVKHLVVGDRV 101
Query: 90 AIEPGVPSRYSDETKSGHYNLCPHMAFAATPPYDGTLVKYYLAPEDFLVKLPDHVSFEEG 149
A+EPG+ + + G YNLCP M F ATPP G+L + P D KLP++VS EEG
Sbjct: 102 ALEPGISCWRCNLCREGRYNLCPEMKFFATPPVHGSLANQVVHPADLCFKLPENVSLEEG 161
Query: 150 ACAEPLAVGVHANRLAETSFGKNVVVFXXXXXXXXXXXXXXXXXXXXXXXXDVFENKLER 209
A EPL+VGVHA R AE NV+V DV EN+L
Sbjct: 162 AMCEPLSVGVHACRRAEVGPETNVLVMGAGPIGLVTMLAARAFSVPRIVIVDVDENRLAV 221
Query: 210 SKDFGATNTINSTKYKSEDELTEVIK-SELKGEQPEIAIDCSGAEICIRTAIKVLKAGGS 268
+K GA + T ED +EV + + G ++ DC+G + TA+ + GG
Sbjct: 222 AKQLGADEIVQVTT-NLEDVGSEVEQIQKAMGSNIDVTFDCAGFNKTMSTALAATRCGGK 280
Query: 269 YVQVGMGKDNINFPIAMIGAKELRVLGSFRYYFNDYKIAVKLISEGKVNVKKMITHTFKF 328
VGMG + P+ A+E+ V+G FRY N + + ++ ++ GK++VK +ITH F F
Sbjct: 281 VCLVGMGHGIMTVPLTPAAAREVDVVGVFRYK-NTWPLCLEFLTSGKIDVKPLITHRFGF 339
Query: 329 --EEAIDAYNFNLEHGSEVVKTMID 351
+E DA+ + GS +K M +
Sbjct: 340 SQKEVEDAFETS-ARGSNAIKVMFN 363
>Hs20549232 [Q] KOG0024 Sorbitol dehydrogenase
Length = 240
Score = 154 bits (389), Expect = 2e-37
Identities = 82/212 (38%), Positives = 114/212 (53%), Gaps = 2/212 (0%)
Query: 40 GICGSDIHYYTHGSIGEFVVKKPMVLGHXXXXXXXXXXKDVTLVQVGDRVAIEPGVPSRY 99
GICGSD+HY+ +G IG F+VKKPMVLGH V ++ GDRVAIE G P
Sbjct: 5 GICGSDVHYWEYGRIGNFIVKKPMVLGHEASGTVEKVGSSVKHLKPGDRVAIESGAPREN 64
Query: 100 SDETKSGHYNLCPHMAFAATPPYDGTLVKYYLAPEDFLVKLPDHVSFEEGACAEPLAVGV 159
+ K G YNL P + F ATPP DG L ++Y F KLPD+V+FEEGA +PL+VG+
Sbjct: 65 DEFCKMGRYNLSPSIFFCATPPDDGNLCQFYKHNAAFCYKLPDNVTFEEGALIDPLSVGI 124
Query: 160 HANRLAETSFGKNVVVFXXXXXXXXXXXXXXXXXXXXXXXXDVFENKLERSKDFGATNTI 219
HA R + G V+V D+ +L ++K+ GA +
Sbjct: 125 HACRRGGVTLGHKVLVCGAGAIGVVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVL 184
Query: 220 NSTKYKSEDELTEVIKSELKGEQPEIAIDCSG 251
+K +S E+ ++ L G +PE+ I+C+G
Sbjct: 185 QISK-ESPQEIARKVEG-LLGCKPEVTIECTG 214
>Hs18583841 [Q] KOG0024 Sorbitol dehydrogenase
Length = 240
Score = 153 bits (386), Expect = 4e-37
Identities = 81/212 (38%), Positives = 113/212 (53%), Gaps = 2/212 (0%)
Query: 40 GICGSDIHYYTHGSIGEFVVKKPMVLGHXXXXXXXXXXKDVTLVQVGDRVAIEPGVPSRY 99
GICGSD+HY+ +G IG F+VKKPMVLGH ++ GDRVAIE G P
Sbjct: 5 GICGSDVHYWEYGRIGNFIVKKPMVLGHEASGTVEKVGSSAKHLKPGDRVAIESGAPREN 64
Query: 100 SDETKSGHYNLCPHMAFAATPPYDGTLVKYYLAPEDFLVKLPDHVSFEEGACAEPLAVGV 159
+ K G YNL P + F ATPP DG L ++Y F KLPD+V+FEEGA +PL+VG+
Sbjct: 65 DEFCKMGRYNLSPSIFFCATPPDDGNLCRFYKHNAAFCYKLPDNVTFEEGALIDPLSVGI 124
Query: 160 HANRLAETSFGKNVVVFXXXXXXXXXXXXXXXXXXXXXXXXDVFENKLERSKDFGATNTI 219
HA R + G V+V D+ +L ++K+ GA +
Sbjct: 125 HACRRGGVTLGHKVLVCGAGAIGVVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVL 184
Query: 220 NSTKYKSEDELTEVIKSELKGEQPEIAIDCSG 251
+K +S E+ ++ L G +PE+ I+C+G
Sbjct: 185 QISK-ESPQEIARKVEG-LLGCKPEVTIECTG 214
>YAL061w [Q] KOG0024 Sorbitol dehydrogenase
Length = 417
Score = 104 bits (259), Expect = 2e-22
Identities = 83/358 (23%), Positives = 144/358 (40%), Gaps = 33/358 (9%)
Query: 6 KAVVLQKKGEITFED-IPAPEITDSHYVKIHVKKTGICGSDIHYYTHGSIGEFVVKK--- 61
+A+ KG I F + + P I + I ++ GICG+D+H YT G I F +
Sbjct: 2 RALAYFGKGNIRFTNHLKEPHIVAPDELVIDIEWCGICGTDLHEYTDGPI--FFPEDGHT 59
Query: 62 --------PMVLGHXXXXXXXXXXKDVTLVQVGDRVAIEP--------------GVPSRY 99
P +GH V ++VGD+V +EP V +
Sbjct: 60 HEISHNPLPQAMGHEMAGTVLEVGPGVKNLKVGDKVVVEPTGTCRDRYRWPLSPNVDKEW 119
Query: 100 SDETKSGHYNLCPHMAFAATPPYDGTLVKYYLAPEDFLVKLPDHVSFEEGACAEPLAVGV 159
K G+YN+C ++ G + + E K+PD V + A +PLAV
Sbjct: 120 CAACKKGYYNICSYLGLCGAGVQSGGFAERVVMNESHCYKVPDFVPLDVAALIQPLAVCW 179
Query: 160 HANRLAETSFGKNVVVFXXXXXXXXXXXXXXXXXXXXXXXXDVFENKLERSKDFGATNTI 219
HA R+ E G ++ + + + E ++ GA
Sbjct: 180 HAIRVCEFKAGSTALIIGAGPIGLGTILALNAAGCKDIVVSEPAKVRRELAEKMGA-RVY 238
Query: 220 NSTKYKSEDELTEVIKSELKGEQPEIAIDCSGAEICIRTAIKVLKAGGSYVQVGM-GKDN 278
+ T + +++ + + G+ + DCSG E+ + AI+ L G+ V + M G
Sbjct: 239 DPTAHAAKESIDYLRSIADGGDGFDYTFDCSGLEVTLNAAIQCLTFRGTAVNLAMWGHHK 298
Query: 279 INFPIAMIGAKELRVLGSFRYYFNDYKIAVKLISEGKVNV---KKMITHTFKFEEAID 333
I F I E + GS Y +D++ ++ + EG++++ + MIT E+ +D
Sbjct: 299 IQFSPMDITLHERKYTGSMCYTHHDFEAVIEALEEGRIDIDRARHMITGRVNIEDGLD 356
>YAL060w [Q] KOG0024 Sorbitol dehydrogenase
Length = 382
Score = 103 bits (258), Expect = 3e-22
Identities = 91/378 (24%), Positives = 155/378 (40%), Gaps = 39/378 (10%)
Query: 6 KAVVLQKKGEITF-EDIPAPEITDSHYVKIHVKKTGICGSDIHYYTHGSIGEFVVKK--- 61
+A+ KKG+I F DIP PEI V I V GICGSD+H Y G I F+ K
Sbjct: 2 RALAYFKKGDIHFTNDIPRPEIQTDDEVIIDVSWCGICGSDLHEYLDGPI--FMPKDGEC 59
Query: 62 --------PMVLGHXXXXXXXXXXKDVTLVQVGDRVAIEPG--------------VPSRY 99
P+ +GH VT V+VGD V ++ S+
Sbjct: 60 HKLSNAALPLAMGHEMSGIVSKVGPKVTKVKVGDHVVVDAASSCADLHCWPHSKFYNSKP 119
Query: 100 SDETKSGHYNLCPHMAFAATPPYDGTLVKYYLAPEDFLVKLPDHVSFEEGACAEPLAVGV 159
D + G NLC H F G + + + ++ +P + + A EPL+V
Sbjct: 120 CDACQRGSENLCTHAGFVGLGVISGGFAEQVVVSQHHIIPVPKEIPLDVAALVEPLSVTW 179
Query: 160 HANRLAETSFGKNVVVFXXXXXXXXXXXXXXXXXXXXXXXXDVFENKLERSKDFGATNTI 219
HA +++ G + +V ++ E ++E +K G
Sbjct: 180 HAVKISGFKKGSSALVLGAGPIGLCTILVLKGMGASKIVVSEIAERRIEMAKKLG-VEVF 238
Query: 220 NSTK--YKSEDELTEVIKSELKGEQPEIAIDCSGAEICIRTAIKVLKAGGSYVQVGM-GK 276
N +K +KS + L + KS + + + DCSG ++ T++K L G+ + + G
Sbjct: 239 NPSKHGHKSIEILRGLTKSH---DGFDYSYDCSGIQVTFETSLKALTFKGTATNIAVWGP 295
Query: 277 DNINFPIAMIGAKELRVLGSFRYYFNDYKIAVKLISEGKV---NVKKMITHTFKFEEAID 333
+ F + +E + GS Y ++ V+ I G + + K++IT + E+ +
Sbjct: 296 KPVPFQPMDVTLQEKVMTGSIGYVVEAFEEVVRAIHNGDIAMEDCKQLITGKQRIEDGWE 355
Query: 334 -AYNFNLEHGSEVVKTMI 350
+ ++H VK ++
Sbjct: 356 KGFQELMDHKESNVKILL 373
>7300579 [Q] KOG0024 Sorbitol dehydrogenase
Length = 1139
Score = 92.4 bits (228), Expect = 9e-19
Identities = 81/318 (25%), Positives = 135/318 (41%), Gaps = 23/318 (7%)
Query: 22 PAPEITDSHYVKIHVKKTGICGSDIHYYTHGSIGEFVVKKPMVLGHXXXXXXXXXXKDVT 81
P P+ D V I + SDIH Y +G+ + M LGH + V
Sbjct: 817 PRPKDFD---VLIRTGSVAVSNSDIHVYENGNRD----MEAMSLGHDATGIVEELGRCVQ 869
Query: 82 LVQVGDRVAIEPGVPSRYSDETKSGHYNLCPHMAFAATPPYDGTLVKYYLAPEDFLVKLP 141
+ VGDRV +E + D K G YN+C + Y+G L Y P D +LP
Sbjct: 870 HLHVGDRVVMESALSCGICDLCKKGLYNMCSGLV------YNGFLSTYQTHPADLCHRLP 923
Query: 142 DHVSFEEGACAEPLAVGVHANRLAETSFGKNVVVFXXXXXXXXXXXXXXXXXXXXXXXXD 201
+ +S E GA + LA+G A A + NV++
Sbjct: 924 ESISMEAGALTQTLALGCQACFKANVTPTSNVLILGACPTAVAAGICAKAIGAKRVAIAG 983
Query: 202 VFENKLE-RSKDFGATNTINSTKYKSE---DELTEVIKSELKGEQPEIAIDCSGAEICIR 257
L+ ++DFG + ++ S E+ E I S+ + + P+ I+CS + + +
Sbjct: 984 CMAPALDVVARDFG----FQAVEFDSNALFGEVLEAIYSKFR-DWPDCVINCSISAMTMN 1038
Query: 258 TAIKVLKAGGSYVQVGMGKDNINFPIAMIGAKELRVLGSFRYYFNDYKIAVKLISEGKVN 317
A+ L+ G V + +F + K +R++ SFR N Y A++L+ G+ +
Sbjct: 1039 LAVMALQPCGVCVLAECDSECASFNALDVLMKNIRLVPSFR-SANMYPTALQLMQSGRAH 1097
Query: 318 VKKMITHTFKFEEAIDAY 335
++K IT T+ +A +A+
Sbjct: 1098 MQKFITATYPLSKADEAF 1115
>At5g63620 [Q] KOG0022 Alcohol dehydrogenase class III
Length = 383
Score = 77.0 bits (188), Expect = 4e-14
Identities = 88/380 (23%), Positives = 147/380 (38%), Gaps = 48/380 (12%)
Query: 7 AVVLQKKGEITFED--IPAPEITDSHYVKIHVKKTGICGSDIHYYTHGSIGEFVVKKPMV 64
AV + +T E+ IP P+ S+ + I K G+C SD+H GE P V
Sbjct: 15 AVYREPNKPLTIEEFHIPRPK---SNEILIKTKACGVCHSDLHVMK----GEIPFASPCV 67
Query: 65 LGHXXXXXX-----XXXXKDVTLVQVGDRVAIEPGVPSRYSDETKSGHYNLCPHMAF--- 116
+GH K + +G RV +P GH +LC
Sbjct: 68 IGHEITGEVVEHGPLTDHKIINRFPIGSRVVGAFIMPCGTCSYCAKGHDDLCEDFFAYNR 127
Query: 117 AATPPYDGT-------------------LVKYYLAPEDFLVKLPDHVSFEEGA---CAEP 154
A YDG + +Y + P L LP+ + + E A CA
Sbjct: 128 AKGTLYDGETRLFLRHDDSPVYMYSMGGMAEYCVTPAHGLAPLPESLPYSESAILGCAVF 187
Query: 155 LAVGVHANRLAETSFGKNVVVFXXXXXXXXXXXXXXXXXXXXXXXXDVFENKLERSKDFG 214
A G A+ AE G ++ V DV ++KL+++K G
Sbjct: 188 TAYGAMAH-AAEIRPGDSIAVIGIGGVGSSCLQIARAFGASDIIAVDVQDDKLQKAKTLG 246
Query: 215 ATNTINSTKYKSEDELTEVIKSELKGEQPEIAIDCSGAEICIRTAIKVLKAGGSYVQVGM 274
AT+ +N+ K ++ E I+ G ++A++ G +K GG V +G+
Sbjct: 247 ATHIVNAAK----EDAVERIREITGGMGVDVAVEALGKPQTFMQCTLSVKDGGKAVMIGL 302
Query: 275 GKDNI--NFPIAMIGAKELRVLGSF-RYYFNDYKIAVKLISEGKVNVKKMITHTFKFEEA 331
+ I + ++++V+GS+ D VKL G N+ ++ +KFE+A
Sbjct: 303 SQAGSVGEIDINRLVRRKIKVIGSYGGRARQDLPKVVKLAESGIFNLTNAVSSKYKFEDA 362
Query: 332 IDAYNFNLEHGSEVVKTMID 351
A+ +L G V + +++
Sbjct: 363 GKAFQ-DLNEGKIVSRGVVE 381
>YMR083w [Q] KOG0023 Alcohol dehydrogenase class V
Length = 375
Score = 61.2 bits (147), Expect = 2e-09
Identities = 79/317 (24%), Positives = 131/317 (40%), Gaps = 12/317 (3%)
Query: 4 TQKAVVL-QKKGEITFEDIPAPEITDSHYVKIHVKKTGICGSDIHYYTHGSIGEFVVKKP 62
TQK V+ + KG++ ++DIP PE + + I+VK +G+C +D+H + HG VK P
Sbjct: 33 TQKGVIFYENKGKLHYKDIPVPE-PKPNEILINVKYSGVCHTDLHAW-HGD-WPLPVKLP 89
Query: 63 MVLGHXXXXXXXXXXKDVTLVQVGDRVAIEPGVPSRYSDE-TKSGHYNLCPHMAFAATPP 121
+V GH +V +VGD I+ S + E +SGH + CP A +
Sbjct: 90 LVGGHEGAGVVVKLGSNVKGWKVGDLAGIKWLNGSCMTCEFCESGHESNCPD-ADLSGYT 148
Query: 122 YDGTLVKYYLAPEDFLVKLPDHVSFEEGACAEPLAVGVH-ANRLAETSFGKNVVVFXXXX 180
+DG+ ++ A K+ E A V V+ A + A+ G V +
Sbjct: 149 HDGSFQQFATADAIQAAKIQQGTDLAEVAPILCAGVTVYKALKEADLKAGDWVAISGAAG 208
Query: 181 XXXXXXXXXXXXXXXXXXXXDVFENKLERSKDFGATNTINSTKYKSEDELTEVIKSELKG 240
D E K + K G I+ TK K+ + I+ KG
Sbjct: 209 GLGSLAVQYATAMGYRVLGIDAGEEKEKLFKKLGGEVFIDFTKTKN---MVSDIQEATKG 265
Query: 241 EQPEIAIDCSGAEICIRTAIKVLKAGGSYVQVGM-GKDNINFPIAMIGAKELRVLGSFRY 299
P I+ S +E I + + ++ G+ V VG+ + + K + + GS+
Sbjct: 266 -GPHGVINVSVSEAAISLSTEYVRPCGTVVLVGLPANAYVKSEVFSHVVKSINIKGSYVG 324
Query: 300 YFNDYKIAVKLISEGKV 316
D + A+ S G +
Sbjct: 325 NRADTREALDFFSRGLI 341
>SPBC1198.01 [Q] KOG0024 Sorbitol dehydrogenase
Length = 423
Score = 60.8 bits (146), Expect = 3e-09
Identities = 88/380 (23%), Positives = 134/380 (35%), Gaps = 57/380 (15%)
Query: 4 TQKAVVLQKKGEITFEDIPAPEITDSHYVKIHVKKTGIC-GSDIHYYTHGSIGEFVVKKP 62
T KA V + ++P P IT V + IC GSD H ++ G ++K
Sbjct: 36 TMKACVWDGPLNVKIAEVPKPTITHPKDVIVKTTACTICSGSDSHIFSGEMPG---IEKG 92
Query: 63 MVLGHXXXXXXXXXXKDVTLVQVGDRVAIEPGVPSRYSDETKSGHYNLCP---------- 112
+LGH +V +++GDRV I + K Y C
Sbjct: 93 AILGHESCGIVAEKGDEVNNLEIGDRVVIAFDLACGQCSFCKRHEYAACDTTNDSKLMDV 152
Query: 113 -----HMA-FAATP---PYDGTLVKYYLAP--EDFLVKLPDHVSFEEGA-CAEPLAVGVH 160
H A F T G +Y P E KLPD + EG ++ L +H
Sbjct: 153 NYGSHHSAIFGYTKLLGDVPGCQAEYIRVPFAEINCCKLPDDIPDSEGLFMSDVLCTSLH 212
Query: 161 ANRLAETSFGKNVVVFXXXXXXXXXXXXXXXXXXXXXXXXDVFENKLERSKD-FGATNTI 219
A L E G V ++ +V ++E ++ FG T
Sbjct: 213 ACTLGEVKKGDTVAIWGMGPIGLYAGRWAQILGASKVIGIEVVPERIELARQKFGFTVI- 271
Query: 220 NSTKYKSEDELTEVIKS--ELKGEQPEIAIDCSGAEICIRTAIKVLKAGG---------- 267
+E+++V K EL + AI+ SG KV +A G
Sbjct: 272 ------DRNEVSDVPKKIMELVSNGVDCAIEASGFRFSTSILHKVERAVGLETDSPDMIT 325
Query: 268 -------SYVQVGMGKDNIN----FPIAMIGAKELRVLGSFRYYFNDYKIAVKLISEGKV 316
Y V + D + FPI + K L + N + + I GK+
Sbjct: 326 ECLNAVRKYGHVSIIADYVGTSNQFPIGHVVMKHLTIRSGQCPCQNYFGYVIDNIRSGKI 385
Query: 317 NVKKMITHTFKFEEAIDAYN 336
+ + M+T+ KF++ DAYN
Sbjct: 386 DPRWMVTNKIKFDDLPDAYN 405
>CE20628 [Q] KOG0023 Alcohol dehydrogenase class V
Length = 408
Score = 60.1 bits (144), Expect = 5e-09
Identities = 78/356 (21%), Positives = 143/356 (39%), Gaps = 40/356 (11%)
Query: 4 TQKAVVLQKKG-EITFEDIPAPEITDSHYVKIHVKKTGICGSDIHYYTHGSIGEF--VVK 60
TQ+A++ + G + + +P P+ + + + ++ +GIC SD+H + +G+F V K
Sbjct: 9 TQRALIFESYGGPLEIKQLPIPQPNEDELL-VKMEYSGICHSDVHTW----LGDFHYVSK 63
Query: 61 KPMVLGHXXXXXXXXXXKDVTLVQVGDRVAIEPGVPSRYS-----------------DET 103
PM+ GH V Q+GD+V I+ S +
Sbjct: 64 CPMIGGHEGAGSVISVGSKVKNWQIGDKVGIKVSQTLNSSSLNFNIFQLVQGNCLNCEYC 123
Query: 104 KSGHYNLCPHMAFAATPPYDGTLVKYYLAPEDFLVKLPDHVSFEEGACAEPLAVGVHANR 163
++GH LCPH+ Y GT +Y + +K+P S A A L GV A +
Sbjct: 124 QTGHEPLCPHVWNIGVQKY-GTFQEYATIRDVDAIKIPK--SMNMAAAAPVLCGGVTAYK 180
Query: 164 L---AETSFGKNVVVFXXXXXXXXXXXXXXXXXXXXXXXXDVFENKLERSKDFGATNTIN 220
+E G+ V V D +K K GA ++
Sbjct: 181 ALKESEVKSGQIVAVTGAGGGLGSFAIQYARAMGMRVVAID-HPSKEAHCKSLGAEWFVD 239
Query: 221 STKYKSEDELTEVIKSELKGEQPEIAIDCSGAEICIRTAIKVLKAGGSYVQVGMGKDN-I 279
+ + +ED + + E+ ++ + A++ + A++ ++ G+ V VG+ KD+ I
Sbjct: 240 A--FGTEDIVAHI--REITDGGAHGVVNFAAAKVPMEKALEYVRKRGTVVFVGLAKDSKI 295
Query: 280 NFPIAMIGAKELRVLGSFRYYFNDYKIAVKLISEGKVNVKKMITHTFKFEEAIDAY 335
+ +++ GS D A+ ++ G VNV + K E+ + Y
Sbjct: 296 LVDTIPLIFNAVKIKGSIVGSRLDVNEAMDFVARGAVNVPLELV---KLEDVAEVY 348
>At1g22430 [Q] KOG0022 Alcohol dehydrogenase class III
Length = 388
Score = 59.3 bits (142), Expect = 8e-09
Identities = 86/376 (22%), Positives = 141/376 (36%), Gaps = 44/376 (11%)
Query: 4 TQKAVVLQKKGE-ITFEDIPAPEITDSHYVKIHVKKTGICGSDIHYY--THGSIGEFVVK 60
T KA + +K GE + EDI + ++ V+I + T +C +D+ ++ + G I F
Sbjct: 15 TCKAAICRKAGEALVIEDIHV-DPPQAYEVRIKILCTSLCHTDLTFWKLSFGPISRF--- 70
Query: 61 KPMVLGHXXXXXXXXXXKDVTLVQVGDRVAIEPGVPSRYSDETKSGHYNLCPHMA---FA 117
P +LGH ++V + GD V + KS N C A +
Sbjct: 71 -PRILGHEAVGVVESIGENVDGFKQGDVVLPVFHPYCEECKDCKSSKTNWCDRYAEDFIS 129
Query: 118 ATPPY---------DGTLVKYYLAPEDF----------LVKLPDHVSFEEGA---CAEPL 155
T Y G ++ ++L F LVK+ + ++ A C
Sbjct: 130 NTRRYGMASRFKDSSGEVIHHFLFVSSFSEYTVVDIAHLVKISPEIPVDKAALLSCGVST 189
Query: 156 AVGVHANRLAETSFGKNVVVFXXXXXXXXXXXXXXXXXXXXXXXXDVFENKLERSKDFGA 215
+G A ++A G + +F D +K E K FG
Sbjct: 190 GIGA-AWKVANVEEGSTIAIFGLGAVGLAVAEGARLRGAAKIIGIDTNSDKFELGKKFGF 248
Query: 216 TNTINSTKYKSEDELTEVIKSELKGEQPEIAIDCSGAEICIRTAIKVLKAG-GSYVQVGM 274
T+ IN T E +++EVIK +G + + +C G + A + G G V +GM
Sbjct: 249 TDFINPTLC-GEKKISEVIKEMTEGGV-DYSFECVGLASLLNEAFISTRTGTGKTVMLGM 306
Query: 275 GKDNINFPIAMIGAKELRVL-----GSFRYYFNDYKIAVKLISEGKVNVKKMITHTFKFE 329
K + RV+ G + D I V + ++N+ ITH F+
Sbjct: 307 EKHAAPISLGSFDLLRGRVICGSLFGGLKSKL-DIPILVDHYLKKELNLDSFITHELNFK 365
Query: 330 EAIDAYNFNLEHGSEV 345
E A+ LE G +
Sbjct: 366 EINKAFAL-LEEGKSL 380
>YOL086c [Q] KOG0023 Alcohol dehydrogenase class V
Length = 348
Score = 56.6 bits (135), Expect = 5e-08
Identities = 69/274 (25%), Positives = 117/274 (42%), Gaps = 11/274 (4%)
Query: 4 TQKAVVL-QKKGEITFEDIPAPEITDSHYVKIHVKKTGICGSDIHYYTHGSIGEFVVKKP 62
TQK V+ + G++ ++DIP P+ ++ + I+VK +G+C +D+H + HG VK P
Sbjct: 6 TQKGVIFYESHGKLEYKDIPVPK-PKANELLINVKYSGVCHTDLHAW-HGD-WPLPVKLP 62
Query: 63 MVLGHXXXXXXXXXXKDVTLVQVGDRVAIEPGVPSRYSDE-TKSGHYNLCPHMAFAATPP 121
+V GH ++V ++GD I+ S + E + G+ + CPH A +
Sbjct: 63 LVGGHEGAGVVVGMGENVKGWKIGDYAGIKWLNGSCMACEYCELGNESNCPH-ADLSGYT 121
Query: 122 YDGTLVKYYLAPEDFLVKLPDHVSFEEGACAEPLAVGVH-ANRLAETSFGKNVVVFXXXX 180
+DG+ +Y A +P + A + V+ A + A G V +
Sbjct: 122 HDGSFQQYATADAVQAAHIPQGTDLAQVAPILCAGITVYKALKSANLMAGHWVAISGAAG 181
Query: 181 XXXXXXXXXXXXXXXXXXXXDVFENKLERSKDFGATNTINSTKYKSEDELTEVIKSELKG 240
D E K E + G I+ TK K D + V+K+ G
Sbjct: 182 GLGSLAVQYAKAMGYRVLGIDGGEGKEELFRSIGGEVFIDFTKEK--DIVGAVLKATDGG 239
Query: 241 EQPEIAIDCSGAEICIRTAIKVLKAGGSYVQVGM 274
I+ S +E I + + ++A G+ V VGM
Sbjct: 240 AHG--VINVSVSEAAIEASTRYVRANGTTVLVGM 271
>SPCC13B11.01 [Q] KOG0023 Alcohol dehydrogenase class V
Length = 350
Score = 55.1 bits (131), Expect = 2e-07
Identities = 72/329 (21%), Positives = 128/329 (38%), Gaps = 36/329 (10%)
Query: 5 QKAVVLQKKG---EITFEDIPAPEITDSHYVKIHVKKTGICGSDIHYYTHGSIGEFVV-- 59
Q A V G + FE++P E V +++K TG+C +D+H G++ +
Sbjct: 7 QLAAVFHTHGGPENVKFEEVPVAEPGQDE-VLVNIKYTGVCHTDLHALQ----GDWPLPA 61
Query: 60 KKPMVLGHXXXXXXXXXXKDVTLVQVGDRVAIEPGVPSRYSDE-TKSGHYNLCPHMAFAA 118
K P++ GH VT +++GDRV ++ S + E +CPH+ +
Sbjct: 62 KMPLIGGHEGAGVVVKVGAGVTRLKIGDRVGVKWMNSSCGNCEYCMKAEETICPHIQLSG 121
Query: 119 TPPYDGTLVKYYLAPEDFLVKLPDHVSFEEGACAEPLAVGVHANRLAETSF---GKNVVV 175
DGT Y +A +P+ V E A + G+ R + S G+ + +
Sbjct: 122 Y-TVDGTFQHYCIANATHATIIPESVPLE--VAAPIMCAGITCYRALKESKVGPGEWICI 178
Query: 176 FXXXXXXXXXXXXXXXXXXXXXXXXDVFENKLERSKDFGATNTINSTKYKSEDELTEVIK 235
D ++K E K FGA ++ +K E ++ E +K
Sbjct: 179 PGAGGGLGHLAVQYAKAMAMRVVAIDTGDDKAELVKSFGAEVFLD---FKKEADMIEAVK 235
Query: 236 SELKGEQPEIAIDCSGAEICIRTAIKVLKAGGSYVQVGMGKDNINFPI-AMIGA------ 288
+ G + + + T+ K + + + G ++ P A +GA
Sbjct: 236 AATNGG--------AHGTLVLSTSPKSYEQAAGFARPGSTMVTVSMPAGAKLGADIFWLT 287
Query: 289 -KELRVLGSFRYYFNDYKIAVKLISEGKV 316
K L++ GS D A++ +S G V
Sbjct: 288 VKMLKICGSHVGNRIDSIEALEYVSRGLV 316
>Hs4501935 [Q] KOG0022 Alcohol dehydrogenase class III
Length = 392
Score = 53.5 bits (127), Expect = 5e-07
Identities = 75/356 (21%), Positives = 132/356 (37%), Gaps = 45/356 (12%)
Query: 29 SHYVKIHVKKTGICGSDIHYYTHGSIGEFVVKKPMVLGHXXXXXXXXXXKDVTLVQVGDR 88
+H V+I + T +C +D G + P+++GH VT V+ GD+
Sbjct: 34 AHEVRIQIIATSLCHTDASVIDSKFEG---LAFPVIVGHEAAGIVESIGPGVTNVKPGDK 90
Query: 89 VAIEPGVPSRYSDETKSGHYNLCPHMAFAATPPYD------------------------G 124
V R S NLC ++ +P D
Sbjct: 91 VIPLYAPLCRKCKFCLSPLTNLCGKISNLKSPASDQQLMEDKTSRFTCKGKPVYHFFGTS 150
Query: 125 TLVKYYLAPEDFLVKLPDHVSFEEG---ACAEPLAVGVHANRLAETSFGKNVVVFXXXXX 181
T +Y + + L K+ D + E C G N A+ + G VF
Sbjct: 151 TFSQYTVVSDINLAKIDDDANLERVCLLGCGFSTGYGAAINN-AKVTPGSTCAVFGLGGV 209
Query: 182 XXXXXXXXXXXXXXXXXXXDVFENKLERSKDFGATNTINSTKYKSEDELTEVIKSELKGE 241
D+ K ++K GAT+ +N + EVI KG
Sbjct: 210 GLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLNPRDL--HKPIQEVIIELTKG- 266
Query: 242 QPEIAIDCSGAEICIRTAIKVLKAGG---SYVQVGMGKDNIN-FPIAMIGAKELRVLGSF 297
+ A+DC+G ++ A+ AG +++ V G + FP +I + + G+F
Sbjct: 267 GVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAAGSKGLTIFPEELIIGRTIN--GTF 324
Query: 298 RYYFNDYKIAVKLISE---GKVNVKKMITHTFKFEEAIDAYNFNLEHGSEVVKTMI 350
+ KL+++ K N+ ++THT F++ +A F+L + + V+T++
Sbjct: 325 FGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDKISEA--FDLMNQGKSVRTIL 378
>At4g22110 [Q] KOG0022 Alcohol dehydrogenase class III
Length = 378
Score = 53.1 bits (126), Expect = 6e-07
Identities = 86/360 (23%), Positives = 135/360 (36%), Gaps = 44/360 (12%)
Query: 6 KAVVLQKKGE-ITFEDIPAPEITDSHYVKIHVKKTGICGSDIHYYTHG---------SIG 55
KA V +K GE + E+I + ++ V+I + T +C +D+ + SIG
Sbjct: 18 KAAVSRKPGEALVIEEIHV-DPPQAYEVRIKIICTSLCHTDVSFSKIDRHEAVGVIESIG 76
Query: 56 EFV-------VKKPMVLGHXXXXXXXXXXKDVTLVQVGDRVAIEP---GVPSRYSDETKS 105
E V V P+ H K + D G+ SR+ D
Sbjct: 77 EHVNGFQQGDVVLPVFHPHCEECRDCKSSKSNWCARFADDFLSNTRRYGMTSRFKDSFGE 136
Query: 106 GHYNLCPHMAFAATPPYDGTLVKYYLAPEDFLVKLPDHVSFEEGA---CAEPLAVGVHAN 162
Y H F ++ +Y + LVK+ + ++ A C +G A
Sbjct: 137 DIY----HFLFVSS------FSEYTVVDIAHLVKISPDIPVDKAALLSCGVSTGIGA-AW 185
Query: 163 RLAETSFGKNVVVFXXXXXXXXXXXXXXXXXXXXXXXXDVFENKLERSKDFGATNTINST 222
++A G V VF D+ K E K FG T+ INST
Sbjct: 186 KVANVEKGSTVAVFGLGAVGLAVGEGARLRGAGKIIGVDLNPEKFELGKKFGFTDFINST 245
Query: 223 KYKSEDELTEVIKSELKGEQPEIAIDCSGAEICIRTAIKVLKAGGSYVQVGMGKDNINFP 282
E++++EVIK E+ G + + +C G + A + G V +G D P
Sbjct: 246 LC-GENKISEVIK-EMTGGGVDYSFECVGLPSLLTEAFSSTRTGSGKTVV-LGIDKHLTP 302
Query: 283 IAMIGAKELR---VLGSFRYYFN---DYKIAVKLISEGKVNVKKMITHTFKFEEAIDAYN 336
+++ LR V GS D I V + ++N+ ITH KFEE A++
Sbjct: 303 VSLGSFDLLRGRHVCGSLFGGLKPKLDIPILVDHYLKKELNLDSFITHELKFEEINKAFD 362
>YBR145w [Q] KOG0023 Alcohol dehydrogenase class V
Length = 351
Score = 52.8 bits (125), Expect = 8e-07
Identities = 66/273 (24%), Positives = 115/273 (41%), Gaps = 11/273 (4%)
Query: 5 QKAVVL-QKKGEITFEDIPAPEITDSHYVKIHVKKTGICGSDIHYYTHGSIGEFVVKKPM 63
QKA+V + G++ ++D+ PE + + +HVK +G+C SD+H + HG F +K P+
Sbjct: 10 QKAIVFYETDGKLEYKDVTVPEPKPNE-ILVHVKYSGVCHSDLHAW-HGD-WPFQLKFPL 66
Query: 64 VLGHXXXXXXXXXXKDVTLVQVGDRVAIEPGVPSRYSDE-TKSGHYNLCPHMAFAATPPY 122
+ GH +V +VGD I+ + S E + G+ + CP++ +
Sbjct: 67 IGGHEGAGVVVKLGSNVKGWKVGDFAGIKWLNGTCMSCEYCEVGNESQCPYLDGTGF-TH 125
Query: 123 DGTLVKYYLAPEDFLVKLPDHVSFEEGACAEPLAVGVH-ANRLAETSFGKNVVVFXXXXX 181
DGT +Y A +P +V+ E A + V+ A + A G+ V +
Sbjct: 126 DGTFQEYATADAVQAAHIPPNVNLAEVAPILCAGITVYKALKRANVIPGQWVTISGACGG 185
Query: 182 XXXXXXXXXXXXXXXXXXXDVFENKLERSKDFGATNTINSTKYKSEDELTEVIKSELKGE 241
D K + + G I+ T+ K D + +IK+ G
Sbjct: 186 LGSLAIQYALAMGYRVIGIDGGNAKRKLFEQLGGEIFIDFTEEK--DIVGAIIKATNGGS 243
Query: 242 QPEIAIDCSGAEICIRTAIKVLKAGGSYVQVGM 274
I+ S +E I + + + G+ V VGM
Sbjct: 244 HG--VINVSVSEAAIEASTRYCRPNGTVVLVGM 274
>At5g42250 [Q] KOG0022 Alcohol dehydrogenase class III
Length = 390
Score = 52.0 bits (123), Expect = 1e-06
Identities = 83/373 (22%), Positives = 138/373 (36%), Gaps = 51/373 (13%)
Query: 6 KAVVLQKKGE--ITFEDIPAPEITDSHYVKIHVKKTGICGSDIHYYTHGSIGEFVVKKPM 63
KA V +K GE + E + AP V+I + T +C SD+ ++ + P
Sbjct: 20 KAAVSRKAGEPLVMEEIMVAPP--QPFEVRIRIICTALCHSDVTFW---KLQVPPACFPR 74
Query: 64 VLGHXXXXXXXXXXKDVTLVQVGDRVAIEPGVPSRYSD-----ETKSGHYNLCPHMAFAA 118
+LGH ++V V GD V +P+ D + KS NLC F
Sbjct: 75 ILGHEAIGVVESVGENVKEVVEGDTV-----LPTFMPDCGDCVDCKSHKSNLCSKFPFKV 129
Query: 119 TP---PYD---------GTLVKYYLAPEDF----------LVKLPDHVSFEEG---ACAE 153
+P YD G + ++L F +VK+ + +C
Sbjct: 130 SPWMPRYDNSSRFTDLNGETLFHFLNVSSFSEYTVLDVANVVKIDSSIPPSRACLLSCGV 189
Query: 154 PLAVGVHANRLAETSFGKNVVVFXXXXXXXXXXXXXXXXXXXXXXXXDVFENKLERSKDF 213
VG A A+ G VV+F D+ K + + F
Sbjct: 190 STGVGA-AWETAKVEKGSTVVIFGLGSIGLAVAEGARLCGASRIIGVDINPTKFQVGQKF 248
Query: 214 GATNTINSTKYKSEDELTEVIKSELKGEQPEIAIDCSGAEICIRTAIKVLKAG-GSYVQV 272
G T +NS + ++ ++EVI +E+ + +C G+ ++ A + G G + +
Sbjct: 249 GVTEFVNSMTCE-KNRVSEVI-NEMTDGGADYCFECVGSSSLVQEAYACCRQGWGKTITL 306
Query: 273 GMGKDNI-----NFPIAMIGAKELRVLGSFRYYFNDYKIAVKLISEGKVNVKKMITHTFK 327
G+ K +F + G + L I +K ++ + K +TH K
Sbjct: 307 GVDKPGSQICLDSFDVLHHGKILMGSLFGGLKAKTHIPILLKRYLSNELELDKFVTHEMK 366
Query: 328 FEEAIDAYNFNLE 340
FEE DA+ LE
Sbjct: 367 FEEINDAFQLLLE 379
>YMR303c [Q] KOG0023 Alcohol dehydrogenase class V
Length = 348
Score = 51.6 bits (122), Expect = 2e-06
Identities = 75/322 (23%), Positives = 129/322 (39%), Gaps = 22/322 (6%)
Query: 4 TQKAVVL-QKKGEITFEDIPAPEITDSHYVKIHVKKTGICGSDIHYYTHGSIGEFVVKKP 62
TQKA++ + G++ +DIP P+ + + I+VK +G+C +D+H + HG K P
Sbjct: 6 TQKAIIFYESNGKLEHKDIPVPKPKPNELL-INVKYSGVCHTDLHAW-HGD-WPLPTKLP 62
Query: 63 MVLGHXXXXXXXXXXKDVTLVQVGDRVAIEPGVPSRYSDE-TKSGHYNLCPHMAFAATPP 121
+V GH ++V ++GD I+ S + E + G+ + CPH A +
Sbjct: 63 LVGGHEGAGVVVGMGENVKGWKIGDYAGIKWLNGSCMACEYCELGNESNCPH-ADLSGYT 121
Query: 122 YDGTLVKYYLAPEDFLVKLPDHVSFEEGACAEPLAVGVH-ANRLAETSFGKNVVVFXXXX 180
+DG+ +Y A +P E A + V+ A + A G +
Sbjct: 122 HDGSFQEYATADAVQAAHIPQGTDLAEVAPILCAGITVYKALKSANLRAGHWAAISGAAG 181
Query: 181 XXXXXXXXXXXXXXXXXXXXDVFENKLERSKDFGATNTINSTKYKSEDELTEVIKSELKG 240
D K E G I+ TK K D ++ V+K+ G
Sbjct: 182 GLGSLAVQYAKAMGYRVLGIDGGPGKEELFTSLGGEVFIDFTKEK--DIVSAVVKATNGG 239
Query: 241 EQPEIAIDCSGAEICIRTAIKVLKAGGSYVQVGM------GKDNINFPIAMIGAKELRVL 294
I+ S +E I + + +A G+ V VG+ D N + K + ++
Sbjct: 240 AHG--IINVSVSEAAIEASTRYCRANGTVVLVGLPAGAKCSSDVFNHVV-----KSISIV 292
Query: 295 GSFRYYFNDYKIAVKLISEGKV 316
GS+ D + A+ + G V
Sbjct: 293 GSYVGNRADTREALDFFARGLV 314
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.317 0.136 0.393
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,342,824
Number of Sequences: 60738
Number of extensions: 761441
Number of successful extensions: 1829
Number of sequences better than 1.0e-05: 27
Number of HSP's better than 0.0 without gapping: 12
Number of HSP's successfully gapped in prelim test: 15
Number of HSP's that attempted gapping in prelim test: 1778
Number of HSP's gapped (non-prelim): 28
length of query: 354
length of database: 30,389,216
effective HSP length: 107
effective length of query: 247
effective length of database: 23,890,250
effective search space: 5900891750
effective search space used: 5900891750
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)