ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIV1451 good I KOG3189 Lipid transport and metabolism Phosphomannomutase
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIV1451 492707 493468 254
(254 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YFL045c [I] KOG3189 Phosphomannomutase 430 e-121
SPAC1556.07 [I] KOG3189 Phosphomannomutase 359 2e-99
At2g45790 [I] KOG3189 Phosphomannomutase 292 4e-79
Hs4557839 [I] KOG3189 Phosphomannomutase 289 3e-78
7294559 [I] KOG3189 Phosphomannomutase 278 5e-75
Hs4505905 [I] KOG3189 Phosphomannomutase 271 5e-73
ECU05g0260 [I] KOG3189 Phosphomannomutase 254 8e-68
CE18722 [I] KOG3189 Phosphomannomutase 218 5e-57
>YFL045c [I] KOG3189 Phosphomannomutase
Length = 254
Score = 430 bits (1106), Expect = e-121
Identities = 209/254 (82%), Positives = 232/254 (91%)
Query: 1 MSVSEFSHKEQPTTLVLFDVDGTLTPARLTVSDEVRDILKRLREKVVIGFVGGSDLSKQL 60
MS++EF++KE+P TLVLFDVDGTLTPARLTVS+EVR L +LR K IGFVGGSDLSKQL
Sbjct: 1 MSIAEFAYKEKPETLVLFDVDGTLTPARLTVSEEVRKTLAKLRNKCCIGFVGGSDLSKQL 60
Query: 61 EQLGSDVLDQFDYAFSENGLTAYRLGKELASQSFIEWIGEEEYNKLAKFILQYLASIDLP 120
EQLG +VLD+FDY+FSENGLTAYRLGKELASQSFI W+GEE+YNKLA FIL+YL+ IDLP
Sbjct: 61 EQLGPNVLDEFDYSFSENGLTAYRLGKELASQSFINWLGEEKYNKLAVFILRYLSEIDLP 120
Query: 121 KRRGTFLEFRNGMINVSPIGRNASTAERNEFEQFDKEHQVRAKFVEALKKEFAHLSLTFS 180
KRRGTFLEFRNGMINVSPIGRNAST ERNEFE++DKEHQ+RAKFVEALKKEF LTFS
Sbjct: 121 KRRGTFLEFRNGMINVSPIGRNASTEERNEFERYDKEHQIRAKFVEALKKEFPDYGLTFS 180
Query: 181 IGGQISFDVFPTGWDKTYCLRHVEADGFKEIHFFGDKTYKGGNDYEIYVDDRTIGHSVES 240
IGGQISFDVFP GWDKTYCL+HVE DGFKEIHFFGDKT GGNDYEI+VD+RTIGHSV+S
Sbjct: 181 IGGQISFDVFPAGWDKTYCLQHVEKDGFKEIHFFGDKTMVGGNDYEIFVDERTIGHSVQS 240
Query: 241 PADTVRILKELFDL 254
P DTV+IL ELF+L
Sbjct: 241 PDDTVKILTELFNL 254
>SPAC1556.07 [I] KOG3189 Phosphomannomutase
Length = 257
Score = 359 bits (922), Expect = 2e-99
Identities = 171/257 (66%), Positives = 210/257 (81%), Gaps = 3/257 (1%)
Query: 1 MSVSEFSHKEQPTTLVLFDVDGTLTPARLTVSDEVRDILKRLREKVVIGFVGGSDLSKQL 60
M+V ++ P TLVLFDVDGTLTPARL+VS E+ + L+ LR+ V IGFVGGSDLSKQ
Sbjct: 1 MAVIPIEERKFPKTLVLFDVDGTLTPARLSVSPEMLETLQNLRKVVAIGFVGGSDLSKQQ 60
Query: 61 EQL---GSDVLDQFDYAFSENGLTAYRLGKELASQSFIEWIGEEEYNKLAKFILQYLASI 117
EQL G +V+D FDYAF+ENGLTAYR G++LASQSFI W+GEE+Y KL F L Y+A +
Sbjct: 61 EQLSVNGENVIDSFDYAFAENGLTAYRYGQQLASQSFIAWLGEEKYQKLVNFCLHYIADL 120
Query: 118 DLPKRRGTFLEFRNGMINVSPIGRNASTAERNEFEQFDKEHQVRAKFVEALKKEFAHLSL 177
D+P +RGTF+EFRNGMIN+SP+GRNA+T ERNEFE+FDK ++RA V+ L+++F L
Sbjct: 121 DIPVKRGTFIEFRNGMINISPVGRNANTEERNEFERFDKGRKIRATMVDVLREKFKDYGL 180
Query: 178 TFSIGGQISFDVFPTGWDKTYCLRHVEADGFKEIHFFGDKTYKGGNDYEIYVDDRTIGHS 237
TFSIGGQISFDVFP GWDKTYCL+HVE +GF IHFFGDKTYKGGNDYEI+VD RTIGHS
Sbjct: 181 TFSIGGQISFDVFPAGWDKTYCLQHVEKEGFDTIHFFGDKTYKGGNDYEIFVDPRTIGHS 240
Query: 238 VESPADTVRILKELFDL 254
V +P DT+ LK++F++
Sbjct: 241 VTNPDDTIAELKKIFNI 257
>At2g45790 [I] KOG3189 Phosphomannomutase
Length = 246
Score = 292 bits (747), Expect = 4e-79
Identities = 143/241 (59%), Positives = 177/241 (73%), Gaps = 2/241 (0%)
Query: 12 PTTLVLFDVDGTLTPARLTVSDEVRDILKRLREKVVIGFVGGSDLSKQLEQLGSDVLDQF 71
P + LFDVDGTLT R + E+ D ++ LR+ V IG VGGSDLSK EQLG V + +
Sbjct: 6 PGVIALFDVDGTLTAPRKEATPELLDFIRELRKVVTIGVVGGSDLSKISEQLGKTVTNDY 65
Query: 72 DYAFSENGLTAYRLGKELASQSFIEWIGEEEYNKLAKFILQYLASIDLPKRRGTFLEFRN 131
DY FSENGL A++ GK + QS +G+++ +L F L Y+A +D+P +RGTF+EFRN
Sbjct: 66 DYCFSENGLVAHKDGKSIGIQSLKLHLGDDKLKELINFTLHYIADLDIPIKRGTFIEFRN 125
Query: 132 GMINVSPIGRNASTAERNEFEQFDKEHQVRAKFVEALKKEFAHLSLTFSIGGQISFDVFP 191
GM+NVSPIGRN S ER+EFE++DK +R K V L++ FAHL+LTFSIGGQISFDVFP
Sbjct: 126 GMLNVSPIGRNCSQEERDEFERYDKVQNIRPKMVAELRERFAHLNLTFSIGGQISFDVFP 185
Query: 192 TGWDKTYCLRHVEADGFKEIHFFGDKTYKGGNDYEIYVDDRTIGHSVESPADTVRILKEL 251
GWDKTYCL+++E F EIHFFGDKTY+GGNDYEIY +TIGHSV SP DTV K L
Sbjct: 186 KGWDKTYCLQYLE--DFSEIHFFGDKTYEGGNDYEIYESPKTIGHSVTSPDDTVAKCKAL 243
Query: 252 F 252
F
Sbjct: 244 F 244
>Hs4557839 [I] KOG3189 Phosphomannomutase
Length = 246
Score = 289 bits (739), Expect = 3e-78
Identities = 142/238 (59%), Positives = 175/238 (72%)
Query: 15 LVLFDVDGTLTPARLTVSDEVRDILKRLREKVVIGFVGGSDLSKQLEQLGSDVLDQFDYA 74
L LFDVDGTLT R ++ E+ D L++LR+K+ IG VGGSD K EQLG+DV++++DY
Sbjct: 8 LCLFDVDGTLTAPRQKITKEMDDFLQKLRQKIKIGVVGGSDFEKVQEQLGNDVVEKYDYV 67
Query: 75 FSENGLTAYRLGKELASQSFIEWIGEEEYNKLAKFILQYLASIDLPKRRGTFLEFRNGMI 134
F ENGL AY+ GK L Q+ +GE L + L Y+A I LPK+RGTF+EFRNGM+
Sbjct: 68 FPENGLVAYKDGKLLCRQNIQSHLGEALIQDLINYCLSYIAKIKLPKKRGTFIEFRNGML 127
Query: 135 NVSPIGRNASTAERNEFEQFDKEHQVRAKFVEALKKEFAHLSLTFSIGGQISFDVFPTGW 194
NVSPIGR+ S ER EF + DK+ +R KFV L+KEFA LTFSIGGQISFDVFP GW
Sbjct: 128 NVSPIGRSCSQEERIEFYELDKKENIRQKFVADLRKEFAGKGLTFSIGGQISFDVFPDGW 187
Query: 195 DKTYCLRHVEADGFKEIHFFGDKTYKGGNDYEIYVDDRTIGHSVESPADTVRILKELF 252
DK YCLRHVE DG+K I+FFGDKT GGND+EI+ D RT+G+SV +P DT RI + LF
Sbjct: 188 DKRYCLRHVENDGYKTIYFFGDKTMPGGNDHEIFTDPRTMGYSVTAPEDTRRICELLF 245
>7294559 [I] KOG3189 Phosphomannomutase
Length = 254
Score = 278 bits (711), Expect = 5e-75
Identities = 139/243 (57%), Positives = 174/243 (71%), Gaps = 3/243 (1%)
Query: 15 LVLFDVDGTLTPARLTVSDEVRDIL-KRLREKVVIGFVGGSDLSKQLEQL-GSDVLDQFD 72
L+LFDVDGTLT R V+ E + R++ + IG VGGSDL K EQL G +L++FD
Sbjct: 12 LLLFDVDGTLTMPRSVVTPEFEEFFYSRVKPRATIGIVGGSDLEKMFEQLNGRKILNEFD 71
Query: 73 YAFSENGLTAYRLGKELASQSFIEWIGEEEYNKLAKFILQYLASIDLPKRRGTFLEFRNG 132
+ F ENGL GKE+ Q+ I +GEE + F+L+YL+ +D+P +RGTF+EFRNG
Sbjct: 72 FIFPENGLVQIEGGKEVGKQNIIMHLGEETVKRFINFVLRYLSELDVPIKRGTFIEFRNG 131
Query: 133 MINVSPIGRNASTAERNEFEQFDKEHQVRAKFVEALKKEFAHLSLTFSIGGQISFDVFPT 192
M+NV PIGR + ERN F ++D EH+VR K ++ LK+EFA + LT+SIGGQISFDVFP
Sbjct: 132 MMNVCPIGRQCTREERNMFAEYDIEHKVREKMIKDLKQEFADVDLTYSIGGQISFDVFPH 191
Query: 193 GWDKTYCLRHVEAD-GFKEIHFFGDKTYKGGNDYEIYVDDRTIGHSVESPADTVRILKEL 251
GWDKTYCLRH+EA FKEIHFFGDKT GGNDYEIY D RTI H V +P DT RIL E+
Sbjct: 192 GWDKTYCLRHIEAHYKFKEIHFFGDKTEPGGNDYEIYSDPRTISHRVYTPKDTQRILTEI 251
Query: 252 FDL 254
+L
Sbjct: 252 LEL 254
>Hs4505905 [I] KOG3189 Phosphomannomutase
Length = 262
Score = 271 bits (694), Expect = 5e-73
Identities = 135/254 (53%), Positives = 176/254 (69%), Gaps = 2/254 (0%)
Query: 1 MSVSEFSHKEQPTTLVLFDVDGTLTPARLTVSDEVRDILKRLREKVVIGFVGGSDLSKQL 60
M+V+ + + + L LFDVDGTLTPAR + EV L++LR +V IG VGGSD K
Sbjct: 1 MAVTAQAARRRERVLCLFDVDGTLTPARQKIDPEVAAFLQKLRSRVQIGVVGGSDYCKIA 60
Query: 61 EQLGS--DVLDQFDYAFSENGLTAYRLGKELASQSFIEWIGEEEYNKLAKFILQYLASID 118
EQLG +V+++FDY F+ENG Y+ G+ L+ Q+ +GEE L F L Y+A +
Sbjct: 61 EQLGDGDEVIEKFDYVFAENGTVQYKHGRLLSKQTIQNHLGEELLQDLINFCLSYMALLR 120
Query: 119 LPKRRGTFLEFRNGMINVSPIGRNASTAERNEFEQFDKEHQVRAKFVEALKKEFAHLSLT 178
LPK+RGTF+EFRNGM+N+SPIGR+ + ER EF + DK+ ++R KFVE LK EFA L
Sbjct: 121 LPKKRGTFIEFRNGMLNISPIGRSCTLEERIEFSELDKKEKIREKFVEDLKTEFAGKGLR 180
Query: 179 FSIGGQISFDVFPTGWDKTYCLRHVEADGFKEIHFFGDKTYKGGNDYEIYVDDRTIGHSV 238
FS GG ISFDVFP GWDK YCL ++ D F IHFFG++T GGND+EI+ D RT+GHSV
Sbjct: 181 FSRGGMISFDVFPEGWDKRYCLDSLDQDSFDTIHFFGNETSPGGNDFEIFADPRTVGHSV 240
Query: 239 ESPADTVRILKELF 252
SP DTV+ +E+F
Sbjct: 241 VSPQDTVQRCREIF 254
>ECU05g0260 [I] KOG3189 Phosphomannomutase
Length = 256
Score = 254 bits (649), Expect = 8e-68
Identities = 122/233 (52%), Positives = 165/233 (70%)
Query: 14 TLVLFDVDGTLTPARLTVSDEVRDILKRLREKVVIGFVGGSDLSKQLEQLGSDVLDQFDY 73
T+ LFDVDGTL+ +R + +++ +L+ LR KV IGFVGGSDL+KQ EQ+G ++L+ FDY
Sbjct: 7 TIFLFDVDGTLSESRAKMPEKMGKMLESLRRKVRIGFVGGSDLAKQKEQVGDNILEIFDY 66
Query: 74 AFSENGLTAYRLGKELASQSFIEWIGEEEYNKLAKFILQYLASIDLPKRRGTFLEFRNGM 133
F ENG++ Y+ G + + I+ +GEE Y + A F+L+YL+ IDLP +RG F+E+RN M
Sbjct: 67 GFPENGVSFYKNGTLESQEKIIDVLGEEFYKEFANFVLRYLSDIDLPIKRGNFIEYRNSM 126
Query: 134 INVSPIGRNASTAERNEFEQFDKEHQVRAKFVEALKKEFAHLSLTFSIGGQISFDVFPTG 193
IN+SPIGRN S ER +F + DK+ + R K V A++ F L FSIGGQIS D FP G
Sbjct: 127 INISPIGRNCSREERMKFFELDKKEKFREKMVTAMRDRFKDSCLVFSIGGQISIDCFPKG 186
Query: 194 WDKTYCLRHVEADGFKEIHFFGDKTYKGGNDYEIYVDDRTIGHSVESPADTVR 246
WDKTYCLRH++ +G + ++FFGD T +GGNDYEIY G SV +P DT R
Sbjct: 187 WDKTYCLRHIKKEGVENVYFFGDMTMEGGNDYEIYNHKDVHGISVGNPDDTYR 239
>CE18722 [I] KOG3189 Phosphomannomutase
Length = 245
Score = 218 bits (556), Expect = 5e-57
Identities = 115/245 (46%), Positives = 153/245 (61%), Gaps = 29/245 (11%)
Query: 35 VRDILKRLREKVVIGFVGGSDLSKQLEQLGSD------------------------VLDQ 70
+R+ L R++V + VGGSD K EQL VL
Sbjct: 1 MREFLIEARKRVPLAIVGGSDFKKITEQLADHDKDLCMSLLIFFFELQILISSFFPVLSL 60
Query: 71 FDYAFSENGLTAYRLGKELASQSFIEWIGEEEYNKLAKFILQYLASIDLPKRRGTFLEFR 130
FDY FSENGL ++ + QS + IG+ + +L F L+Y++ I LP +RG F+EFR
Sbjct: 61 FDYTFSENGLYGFKGTEPYPVQSIQKAIGDAKLQELINFALRYMSDIQLPVKRGNFVEFR 120
Query: 131 NGMINVSPIGRNASTAERNEFEQFDKEHQVRAKFVEALKKEFAHLSLTFSIGGQISFDVF 190
NGMIN+SPIGR+ S ER +F +FDK+H +R KF E L+++F L F+IGGQIS DVF
Sbjct: 121 NGMINLSPIGRSCSQEERMQFVEFDKKHGIRQKFTEQLREKFGQYGLQFAIGGQISVDVF 180
Query: 191 PTGWDKTYCLRHVEADGFKEIHFFGDKTYKGGNDYEIYVDDRTIGHSVESPADTVR---- 246
PTGWDKT+CL+++ D F IHFFGDKT GGND+EI+ D+RT+GH+VE P DT +
Sbjct: 181 PTGWDKTFCLQYLVPD-FDTIHFFGDKTAPGGNDHEIFADERTVGHTVEGPEDTRKHVEN 239
Query: 247 ILKEL 251
+LKEL
Sbjct: 240 VLKEL 244
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.319 0.139 0.398
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,307,966
Number of Sequences: 60738
Number of extensions: 664854
Number of successful extensions: 1651
Number of sequences better than 1.0e-05: 8
Number of HSP's better than 0.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 1635
Number of HSP's gapped (non-prelim): 8
length of query: 254
length of database: 30,389,216
effective HSP length: 104
effective length of query: 150
effective length of database: 24,072,464
effective search space: 3610869600
effective search space used: 3610869600
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)