ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIV1495 good O KOG1339 Posttranslational modification, protein turnover, chaperones Aspartyl protease
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIV1495 507555 508781 409
(409 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YPL154c [O] KOG1339 Aspartyl protease 600 e-171
7304149 [O] KOG1339 Aspartyl protease 322 6e-88
Hs4503143 [O] KOG1339 Aspartyl protease 285 7e-77
CE03567 [O] KOG1339 Aspartyl protease 284 1e-76
7303185 [O] KOG1339 Aspartyl protease 284 1e-76
Hs4503145 [O] KOG1339 Aspartyl protease 274 2e-73
7297427 [O] KOG1339 Aspartyl protease 271 2e-72
Hs4505757 [O] KOG1339 Aspartyl protease 270 2e-72
Hs4758754 [O] KOG1339 Aspartyl protease 268 1e-71
7297766 [O] KOG1339 Aspartyl protease 258 9e-69
CE19495 [O] KOG1339 Aspartyl protease 258 1e-68
7296076 [O] KOG1339 Aspartyl protease 248 9e-66
7297765 [O] KOG1339 Aspartyl protease 239 7e-63
Hs4506475 [O] KOG1339 Aspartyl protease 235 1e-61
At1g11910 [O] KOG1339 Aspartyl protease 234 1e-61
At1g62290 [O] KOG1339 Aspartyl protease 233 3e-61
At4g04460 [O] KOG1339 Aspartyl protease 231 1e-60
7300255 [O] KOG1339 Aspartyl protease 229 4e-60
7296075 [O] KOG1339 Aspartyl protease 214 2e-55
CE21681 [O] KOG1339 Aspartyl protease 206 5e-53
7290034 [O] KOG1339 Aspartyl protease 206 5e-53
7300253 [O] KOG1339 Aspartyl protease 201 1e-51
Hs22063875 [O] KOG1339 Aspartyl protease 196 4e-50
Hs22063872 [O] KOG1339 Aspartyl protease 196 4e-50
CE04971 [O] KOG1339 Aspartyl protease 196 7e-50
7296077 [O] KOG1339 Aspartyl protease 193 3e-49
CE21685 [O] KOG1339 Aspartyl protease 189 8e-48
CE20430 [O] KOG1339 Aspartyl protease 187 2e-47
CE16843 [O] KOG1339 Aspartyl protease 183 4e-46
CE09542 [O] KOG1339 Aspartyl protease 183 4e-46
CE09540 [O] KOG1339 Aspartyl protease 180 3e-45
CE09539 [O] KOG1339 Aspartyl protease 178 1e-44
7300254 [O] KOG1339 Aspartyl protease 177 2e-44
7296074 [O] KOG1339 Aspartyl protease 164 3e-40
CE11478 [O] KOG1339 Aspartyl protease 161 1e-39
CE21684 [O] KOG1339 Aspartyl protease 157 3e-38
CE05287 [O] KOG1339 Aspartyl protease 155 1e-37
CE11480 [O] KOG1339 Aspartyl protease 153 5e-37
CE21683 [O] KOG1339 Aspartyl protease 152 9e-37
CE09738 [O] KOG1339 Aspartyl protease 150 3e-36
YLR121c [O] KOG1339 Aspartyl protease 131 2e-30
At1g69100 [O] KOG1339 Aspartyl protease 128 2e-29
Hs22063919 [O] KOG1339 Aspartyl protease 125 1e-28
At4g22050 [O] KOG1339 Aspartyl protease 124 2e-28
CE09541 [O] KOG1339 Aspartyl protease 118 2e-26
Hs22050827 [O] KOG1339 Aspartyl protease 108 1e-23
YLR120c [O] KOG1339 Aspartyl protease 99 9e-21
Hs21040360 [O] KOG1339 Aspartyl protease 97 3e-20
Hs6912266 [O] KOG1339 Aspartyl protease 97 6e-20
Hs21040362 [O] KOG1339 Aspartyl protease 96 7e-20
Hs19923395 [O] KOG1339 Aspartyl protease 96 7e-20
Hs21040366 [O] KOG1339 Aspartyl protease 94 4e-19
YDR144c [O] KOG1339 Aspartyl protease 87 3e-17
YIL015w [O] KOG1339 Aspartyl protease 86 1e-16
SPAC26A3.01 [O] KOG1339 Aspartyl protease 81 2e-15
Hs21040364 [O] KOG1339 Aspartyl protease 78 3e-14
CE04749 [O] KOG1339 Aspartyl protease 76 1e-13
YIR039c [O] KOG1339 Aspartyl protease 73 7e-13
CE09538 [O] KOG1339 Aspartyl protease 72 2e-12
At2g36670 [O] KOG1339 Aspartyl protease 68 2e-11
At3g50050 [O] KOG1339 Aspartyl protease 67 6e-11
At3g02740 [O] KOG1339 Aspartyl protease 62 2e-09
SPCC1795.09 [O] KOG1339 Aspartyl protease 60 4e-09
At1g65240 [O] KOG1339 Aspartyl protease 60 4e-09
At5g10760 [O] KOG1339 Aspartyl protease 60 8e-09
Hs21040368 [O] KOG1339 Aspartyl protease 58 2e-08
At3g54400 [O] KOG1339 Aspartyl protease 58 3e-08
At5g43100 [O] KOG1339 Aspartyl protease 56 8e-08
At5g07030 [O] KOG1339 Aspartyl protease 53 9e-07
At3g18490 [O] KOG1339 Aspartyl protease 53 9e-07
At5g33340 [O] KOG1339 Aspartyl protease 52 2e-06
At1g08210 [O] KOG1339 Aspartyl protease 51 3e-06
Hs18549644 [O] KOG1339 Aspartyl protease 50 6e-06
At1g09750 [O] KOG1339 Aspartyl protease 50 6e-06
>YPL154c [O] KOG1339 Aspartyl protease
Length = 405
Score = 600 bits (1546), Expect = e-171
Identities = 285/374 (76%), Positives = 332/374 (88%), Gaps = 4/374 (1%)
Query: 36 LEDQLKDVPFAEHVAQLGEKYLNSFQRAYPQESFSKDNVDVFVAPEGSHSVPLTNYLNAQ 95
L D++K+V F +H+A LG+KYL F++A P+ FS+++ EG H VPLTNYLNAQ
Sbjct: 34 LSDEMKEVTFEQHLAHLGQKYLTQFEKANPEVVFSREHP---FFTEGGHDVPLTNYLNAQ 90
Query: 96 YFTEITLGSPPQSFKVILDTGSSNLWVPSAECGSLACFLHTKYDHEASSTYKANGSEFAI 155
Y+T+ITLG+PPQ+FKVILDTGSSNLWVPS ECGSLACFLH+KYDHEASS+YKANG+EFAI
Sbjct: 91 YYTDITLGTPPQNFKVILDTGSSNLWVPSNECGSLACFLHSKYDHEASSSYKANGTEFAI 150
Query: 156 QYGSGSLEGYVSRDLLTIGDLVIPDQDFAEATSEPGLAFAFGKFDGILGLAYDSISVNRI 215
QYG+GSLEGY+S+D L+IGDL IP QDFAEATSEPGL FAFGKFDGILGL YD+ISV+++
Sbjct: 151 QYGTGSLEGYISQDTLSIGDLTIPKQDFAEATSEPGLTFAFGKFDGILGLGYDTISVDKV 210
Query: 216 VPPVYNAIKNKLLDDPVFAFYLGDSDK-SEDGGEASFGGIDEEKYTGEITWLPVRRKAYW 274
VPP YNAI+ LLD+ FAFYLGD+ K +E+GGEA+FGGIDE K+ G+ITWLPVRRKAYW
Sbjct: 211 VPPFYNAIQQDLLDEKRFAFYLGDTSKDTENGGEATFGGIDESKFKGDITWLPVRRKAYW 270
Query: 275 EVKFEGIGLGEEYATLEGHGAAIDTGTSLIALPSGLAEILNAEIGAKKGWSGQYSVDCES 334
EVKFEGIGLG+EYA LE HGAAIDTGTSLI LPSGLAE++NAEIGAKKGW+GQY++DC +
Sbjct: 271 EVKFEGIGLGDEYAELESHGAAIDTGTSLITLPSGLAEMINAEIGAKKGWTGQYTLDCNT 330
Query: 335 RDSLPDLTLNFNGYNFTITAYDYTLEVSGSCISAFTPMDFPEPVGPLAIIGDAFLRKYYS 394
RD+LPDL NFNGYNFTI YDYTLEVSGSCISA TPMDFPEPVGPLAI+GDAFLRKYYS
Sbjct: 331 RDNLPDLIFNFNGYNFTIGPYDYTLEVSGSCISAITPMDFPEPVGPLAIVGDAFLRKYYS 390
Query: 395 IYDIGHDAVGLAKA 408
IYD+G++AVGLAKA
Sbjct: 391 IYDLGNNAVGLAKA 404
>7304149 [O] KOG1339 Aspartyl protease
Length = 392
Score = 322 bits (825), Expect = 6e-88
Identities = 164/328 (50%), Positives = 208/328 (63%), Gaps = 6/328 (1%)
Query: 87 PLTNYLNAQYFTEITLGSPPQSFKVILDTGSSNLWVPSAECG--SLACFLHTKYDHEASS 144
PL+NY++AQY+ I +GSPPQ+F+V+ DTGSSNLWVPS +C ++AC +H KYD S
Sbjct: 64 PLSNYMDAQYYGPIAIGSPPQNFRVVFDTGSSNLWVPSKKCHLTNIACLMHNKYDASKSK 123
Query: 145 TYKANGSEFAIQYGSGSLEGYVSRDLLTIGDLVIPDQDFAEATSEPGLAFAFGKFDGILG 204
TY NG+EFAIQYGSGSL GY+S D ++I L I DQ FAEA SEPGL F KFDGILG
Sbjct: 124 TYTKNGTEFAIQYGSGSLSGYLSTDTVSIAGLDIKDQTFAEALSEPGLVFVAAKFDGILG 183
Query: 205 LAYDSISVNRIVPPVYNAIKNKLLDDPVFAFYLGDSDKSEDGGEASFGGIDEEKYTGEIT 264
L Y+SISV+++ PP Y + L+ PVF+FYL S +GGE FGG D YTGE T
Sbjct: 184 LGYNSISVDKVKPPFYAMYEQGLISAPVFSFYLNRDPASPEGGEIIFGGSDPNHYTGEFT 243
Query: 265 WLPVRRKAYWEVKFEGIGLGEEYATLEGHGAAIDTGTSLIALPSGLAEILNAEIGAKKGW 324
+LPV RKAYW++K + +G+ G DTGTSLIA P A +N +IG
Sbjct: 244 YLPVTRKAYWQIKMDAASIGDLQLCKGGCQVIADTGTSLIAAPLEEATSINQKIGGTPII 303
Query: 325 SGQYSVDCESRDSLPDLTLNFNGYNFTITAYDYTLEVSGS----CISAFTPMDFPEPVGP 380
GQY V C+ LP + G F + DY L V+ C+S F +D P P GP
Sbjct: 304 GGQYVVSCDLIPQLPVIKFVLGGKTFELEGKDYILRVAQMGKTICLSGFMGLDIPPPNGP 363
Query: 381 LAIIGDAFLRKYYSIYDIGHDAVGLAKA 408
L I+GD F+ KYY+ +D+G+D VG A A
Sbjct: 364 LWILGDVFIGKYYTEFDMGNDRVGFADA 391
>Hs4503143 [O] KOG1339 Aspartyl protease
Length = 412
Score = 285 bits (730), Expect = 7e-77
Identities = 153/358 (42%), Positives = 213/358 (58%), Gaps = 18/358 (5%)
Query: 70 SKDNVDVFVAPEGSHSVPLTNYLNAQYFTEITLGSPPQSFKVILDTGSSNLWVPSAECGS 129
SK + V EG L NY++AQY+ EI +G+PPQ F V+ DTGSSNLWVPS C
Sbjct: 53 SKYSQAVPAVTEGPIPEVLKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKL 112
Query: 130 L--ACFLHTKYDHEASSTYKANGSEFAIQYGSGSLEGYVSRDLLTI-----------GDL 176
L AC++H KY+ + SSTY NG+ F I YGSGSL GY+S+D +++ G +
Sbjct: 113 LDIACWIHHKYNSDKSSTYVKNGTSFDIHYGSGSLSGYLSQDTVSVPCQSASSASALGGV 172
Query: 177 VIPDQDFAEATSEPGLAFAFGKFDGILGLAYDSISVNRIVPPVYNAIKNKLLDDPVFAFY 236
+ Q F EAT +PG+ F KFDGILG+AY ISVN ++P N ++ KL+D +F+FY
Sbjct: 173 KVERQVFGEATKQPGITFIAAKFDGILGMAYPRISVNNVLPVFDNLMQQKLVDQNIFSFY 232
Query: 237 LGDSDKSEDGGEASFGGIDEEKYTGEITWLPVRRKAYWEVKFEGIGLGEEYATL-EGHGA 295
L ++ GGE GG D + Y G +++L V RKAYW+V + + + EG A
Sbjct: 233 LSRDPDAQPGGELMLGGTDSKYYKGSLSYLNVTRKAYWQVHLDQVEVASGLTLCKEGCEA 292
Query: 296 AIDTGTSLIALPSGLAEILNAEIGAKKGWSGQYSVDCESRDSLPDLTLNFNGYNFTITAY 355
+DTGTSL+ P L IGA G+Y + CE +LP +TL G + ++
Sbjct: 293 IVDTGTSLMVGPVDEVRELQKAIGAVPLIQGEYMIPCEKVSTLPAITLKLGGKGYKLSPE 352
Query: 356 DYTLEVSGS----CISAFTPMDFPEPVGPLAIIGDAFLRKYYSIYDIGHDAVGLAKAA 409
DYTL+VS + C+S F MD P P GPL I+GD F+ +YY+++D ++ VG A+AA
Sbjct: 353 DYTLKVSQAGKTLCLSGFMGMDIPPPSGPLWILGDVFIGRYYTVFDRDNNRVGFAEAA 410
>CE03567 [O] KOG1339 Aspartyl protease
Length = 444
Score = 284 bits (727), Expect = 1e-76
Identities = 145/334 (43%), Positives = 205/334 (60%), Gaps = 6/334 (1%)
Query: 81 EGSHSVPLTNYLNAQYFTEITLGSPPQSFKVILDTGSSNLWVPSAECG--SLACFLHTKY 138
EG L NY++AQYF I++G+P Q+F VI DTGSSNLW+PS +C +AC LH +Y
Sbjct: 79 EGEIDELLRNYMDAQYFGTISIGTPAQNFTVIFDTGSSNLWIPSKKCPFYDIACMLHHRY 138
Query: 139 DHEASSTYKANGSEFAIQYGSGSLEGYVSRDLLTIGDLVIPDQDFAEATSEPGLAFAFGK 198
D ++SSTYK +G + AIQYG+GS++G++S+D + + + DQ FAEATSEPG+ F K
Sbjct: 139 DSKSSSTYKEDGRKMAIQYGTGSMKGFISKDSVCVAGVCAEDQPFAEATSEPGITFVAAK 198
Query: 199 FDGILGLAYDSISVNRIVPPVYNAIKNKLLDDPVFAFYLGDSDKSEDGGEASFGGIDEEK 258
FDGILG+AY I+V + P + K + +F+F+L + SE GGE +FGGID +
Sbjct: 199 FDGILGMAYPEIAVLGVQPVFNTLFEQKKVPSNLFSFWLNRNPDSEIGGEITFGGIDSRR 258
Query: 259 YTGEITWLPVRRKAYWEVKFEGIGLGEEYATLEGHGAAIDTGTSLIALPSGLAEILNAEI 318
Y IT++PV RK YW+ K + + G A DTGTSLIA P E + I
Sbjct: 259 YVEPITYVPVTRKGYWQFKMDKVVGSGVLGCSNGCQAIADTGTSLIAGPKAQIEAIQNFI 318
Query: 319 GAKKGWSGQYSVDCESRDSLPDLTLNFNGYNFTITAYDYTLEVSGS----CISAFTPMDF 374
GA+ G+Y + C+ +LP ++ G F++ DY L+VS C+S F +D
Sbjct: 319 GAEPLIKGEYMISCDKVPTLPPVSFVIGGQEFSLKGEDYVLKVSQGGKTICLSGFMGIDL 378
Query: 375 PEPVGPLAIIGDAFLRKYYSIYDIGHDAVGLAKA 408
PE VG L I+GD F+ +YYS++D + VG A+A
Sbjct: 379 PERVGELWILGDVFIGRYYSVFDFDQNRVGFAQA 412
>7303185 [O] KOG1339 Aspartyl protease
Length = 404
Score = 284 bits (727), Expect = 1e-76
Identities = 150/330 (45%), Positives = 200/330 (60%), Gaps = 7/330 (2%)
Query: 85 SVPLTNYLNAQYFTEITLGSPPQSFKVILDTGSSNLWVPSAECGS--LACFLHTKYDHEA 142
S PL+NYL+AQYF IT+G+PPQ+FKVI DTGSSNLWVPSA C S +AC +H +Y +
Sbjct: 74 STPLSNYLDAQYFGPITIGTPPQTFKVIFDTGSSNLWVPSATCASTMVACRVHNRYFAKR 133
Query: 143 SSTYKANGSEFAIQYGSGSLEGYVSRDLLTIGDLVIPDQDFAEATSEPGLAFAFGKFDGI 202
S++++ G FAI YGSGSL G++S D + + L I DQ FAEAT PG F KFDGI
Sbjct: 134 STSHQVRGDHFAIHYGSGSLSGFLSTDTVRVAGLEIRDQTFAEATEMPGPIFLAAKFDGI 193
Query: 203 LGLAYDSISVNRIVPPVYNAIKNKLLDDPVFAFYLGDSDKSEDGGEASFGGIDEEKYTGE 262
GLAY SIS+ RI PP Y ++ LL P+F+ YL + + +DGG FGG + YTG
Sbjct: 194 FGLAYRSISMQRIKPPFYAMMEQGLLTKPIFSVYLSRNGE-KDGGAIFFGGSNPHYYTGN 252
Query: 263 ITWLPVRRKAYWEVKFEGIGLGEEYATLEGHGAAIDTGTSLIALPSGLAEILNAEIGAKK 322
T++ V +AYW+VK + + +G IDTGTS +ALP A ++N IG
Sbjct: 253 FTYVQVSHRAYWQVKMDSAVIRNLELCQQGCEVIIDTGTSFLALPYDQAILINESIGGTP 312
Query: 323 GWSGQYSVDCESRDSLPDLTLNFNGYNFTITAYDYTL----EVSGSCISAFTPMDFPEPV 378
GQ+ V C+S LP +T G F + +++Y + C SAF +D P P
Sbjct: 313 SSFGQFLVPCDSVPDLPKITFTLGGRRFFLESHEYVFRDIYQDRRICSSAFIAVDLPSPS 372
Query: 379 GPLAIIGDAFLRKYYSIYDIGHDAVGLAKA 408
GPL I+GD FL KYY+ +D+ +G A A
Sbjct: 373 GPLWILGDVFLGKYYTEFDMERHRIGFADA 402
>Hs4503145 [O] KOG1339 Aspartyl protease
Length = 396
Score = 274 bits (700), Expect = 2e-73
Identities = 146/357 (40%), Positives = 209/357 (57%), Gaps = 11/357 (3%)
Query: 62 RAYPQESFSKDNVDVFVAPEG-----SHSVPLTNYLNAQYFTEITLGSPPQSFKVILDTG 116
R+ E + N+D+ E S PL NYL+ +YF I++GSPPQ+F VI DTG
Sbjct: 39 RSQLSEFWKSHNLDMIQFTESCSMDQSAKEPLINYLDMEYFGTISIGSPPQNFTVIFDTG 98
Query: 117 SSNLWVPSAECGSLACFLHTKYDHEASSTYKANGSEFAIQYGSGSLEGYVSRDLLTIGDL 176
SSNLWVPS C S AC H+++ SSTY G F+IQYG+GSL G + D +++ L
Sbjct: 99 SSNLWVPSVYCTSPACKTHSRFQPSQSSTYSQPGQSFSIQYGTGSLSGIIGADQVSVEGL 158
Query: 177 VIPDQDFAEATSEPGLAFAFGKFDGILGLAYDSISVNRIVPPVYNAIKNKLLDDPVFAFY 236
+ Q F E+ +EPG F +FDGILGL Y S++V + P N + L+D P+F+ Y
Sbjct: 159 TVVGQQFGESVTEPGQTFVDAEFDGILGLGYPSLAVGGVTPVFDNMMAQNLVDLPMFSVY 218
Query: 237 LGDSDKSEDGGEASFGGIDEEKYTGEITWLPVRRKAYWEVKFEGIGLGEEYA-TLEGHGA 295
+ + + G E FGG D ++G + W+PV ++AYW++ + I +G EG A
Sbjct: 219 MSSNPEGGAGSELIFGGYDHSHFSGSLNWVPVTKQAYWQIALDNIQVGGTVMFCSEGCQA 278
Query: 296 AIDTGTSLIALPSGLAEILNAEIGAKKGWSGQYSVDCESRDSLPDLTLNFNGYNFTITAY 355
+DTGTSLI PS + L IGA G+Y+V+C + + +PD+T NG +T++
Sbjct: 279 IVDTGTSLITGPSDKIKQLQNAIGAAP-VDGEYAVECANLNVMPDVTFTINGVPYTLSPT 337
Query: 356 DYTL--EVSGS--CISAFTPMDFPEPVGPLAIIGDAFLRKYYSIYDIGHDAVGLAKA 408
YTL V G C S F +D P GPL I+GD F+R++YS++D G++ VGLA A
Sbjct: 338 AYTLLDFVDGMQFCSSGFQGLDIHPPAGPLWILGDVFIRQFYSVFDRGNNRVGLAPA 394
>7297427 [O] KOG1339 Aspartyl protease
Length = 372
Score = 271 bits (692), Expect = 2e-72
Identities = 144/328 (43%), Positives = 200/328 (60%), Gaps = 22/328 (6%)
Query: 88 LTNYLNAQYFTEITLGSPPQSFKVILDTGSSNLWVPSAECGSLACFLHTKYDHEASSTYK 147
L+N +N Y+ I++G+P QSFKV+ D+GSSNLWVPS C S AC H +YD ASSTY
Sbjct: 61 LSNSMNMAYYGAISIGTPAQSFKVLFDSGSSNLWVPSNTCKSDACLTHNQYDSSASSTYV 120
Query: 148 ANGSEFAIQYGSGSLEGYVSRDLLTIGDLVIPDQDFAEATSEPGLAFAFGKFDGILGLAY 207
ANG F+IQYG+GSL GY+S D + + L I Q FAE+T+EPG F FDGILG+AY
Sbjct: 121 ANGESFSIQYGTGSLTGYLSTDTVDVNGLSIQSQTFAESTNEPGTNFNDANFDGILGMAY 180
Query: 208 DSISVNRIVPPVYNAIKNKLLDDPVFAFYLGDSDKSEDGGEASFGGIDEEKYTGEITWLP 267
+S++V+ + PP YN + L+D+ VF+FYL S GGE FGG D Y+G +T++P
Sbjct: 181 ESLAVDGVAPPFYNMVSQGLVDNSVFSFYLARDGTSTMGGELIFGGSDASLYSGALTYVP 240
Query: 268 VRRKAYWEVKFEGIGLGEEYATLEGHGAAIDTGTSLIALPSG----LAEILNAEIGAKKG 323
+ + YW+ G + + Y+ + A DTGTSLI P L+EILN + G
Sbjct: 241 ISEQGYWQFTMAGSSI-DGYSLCDDCQAIADTGTSLIVAPYNAYITLSEILNV---GEDG 296
Query: 324 WSGQYSVDCESRDSLPDLTLNFNGYNFTITAYDYTLEVSGSCISAFTPM--DFPEPVGPL 381
+ +DC S SLPD+T N G NF + Y ++ G+C+SAF M DF
Sbjct: 297 Y-----LDCSSVSSLPDVTFNIGGTNFVLKPSAYIIQSDGNCMSAFEYMGTDF------- 344
Query: 382 AIIGDAFLRKYYSIYDIGHDAVGLAKAA 409
I+GD F+ +YY+ +D+G++ +G A A
Sbjct: 345 WILGDVFIGQYYTEFDLGNNRIGFAPVA 372
>Hs4505757 [O] KOG1339 Aspartyl protease
Length = 388
Score = 270 bits (691), Expect = 2e-72
Identities = 137/322 (42%), Positives = 193/322 (59%), Gaps = 4/322 (1%)
Query: 91 YLNAQYFTEITLGSPPQSFKVILDTGSSNLWVPSAECGSLACFLHTKYDHEASSTYKANG 150
Y++A YF EI++G+PPQ+F V+ DTGSSNLWVPS C S AC H++++ SSTY NG
Sbjct: 68 YMDAAYFGEISIGTPPQNFLVLFDTGSSNLWVPSVYCQSQACTSHSRFNPSESSTYSTNG 127
Query: 151 SEFAIQYGSGSLEGYVSRDLLTIGDLVIPDQDFAEATSEPGLAFAFGKFDGILGLAYDSI 210
F++QYGSGSL G+ D LT+ + +P+Q+F + +EPG F + +FDGI+GLAY ++
Sbjct: 128 QTFSLQYGSGSLTGFFGYDTLTVQSIQVPNQEFGLSENEPGTNFVYAQFDGIMGLAYPAL 187
Query: 211 SVNRIVPPVYNAIKNKLLDDPVFAFYLGDSDKSEDGGEASFGGIDEEKYTGEITWLPVRR 270
SV+ + ++ L PVF+ YL + S GG FGG+D YTG+I W PV +
Sbjct: 188 SVDEATTAMQGMVQEGALTSPVFSVYLSNQQGS-SGGAVVFGGVDSSLYTGQIYWAPVTQ 246
Query: 271 KAYWEVKFEGIGLGEEYA--TLEGHGAAIDTGTSLIALPSGLAEILNAEIGAKKGWSGQY 328
+ YW++ E +G + + EG A +DTGTSL+ +P L GA++ GQ+
Sbjct: 247 ELYWQIGIEEFLIGGQASGWCSEGCQAIVDTGTSLLTVPQQYMSALLQATGAQEDEYGQF 306
Query: 329 SVDCESRDSLPDLTLNFNGYNFTITAYDYTLEVSGSCISAFTPMDFPEPVG-PLAIIGDA 387
V+C S +LP LT NG F + Y L +G C P G PL I+GD
Sbjct: 307 LVNCNSIQNLPSLTFIINGVEFPLPPSSYILSNNGYCTVGVEPTYLSSQNGQPLWILGDV 366
Query: 388 FLRKYYSIYDIGHDAVGLAKAA 409
FLR YYS+YD+G++ VG A AA
Sbjct: 367 FLRSYYSVYDLGNNRVGFATAA 388
>Hs4758754 [O] KOG1339 Aspartyl protease
Length = 420
Score = 268 bits (684), Expect = 1e-71
Identities = 145/334 (43%), Positives = 201/334 (59%), Gaps = 11/334 (3%)
Query: 86 VPLTNYLNAQYFTEITLGSPPQSFKVILDTGSSNLWVPSAECG--SLACFLHTKYDHEAS 143
VPL+NY + QYF EI LG+PPQ+F V DTGSSNLWVPS C S+ C+LH ++D +AS
Sbjct: 68 VPLSNYRDVQYFGEIGLGTPPQNFTVAFDTGSSNLWVPSRRCHFFSVPCWLHHRFDPKAS 127
Query: 144 STYKANGSEFAIQYGSGSLEGYVSRDLLTIGDLVIPDQDFAEATSEPGLAFAFGKFDGIL 203
S+++ANG++FAIQYG+G ++G +S D LTIG + F EA EP L FAF FDGIL
Sbjct: 128 SSFQANGTKFAIQYGTGRVDGILSEDKLTIGGIKGASVIFGEALWEPSLVFAFAHFDGIL 187
Query: 204 GLAYDSISVNRIVPPVYNAIKNKLLDDPVFAFYLGDSDKSEDGGEASFGGIDEEKYTGEI 263
GL + +SV + PP+ ++ LLD PVF+FYL + DGGE GG D Y +
Sbjct: 188 GLGFPILSVEGVRPPMDVLVEQGLLDKPVFSFYLNRDPEEPDGGELVLGGSDPAHYIPPL 247
Query: 264 TWLPVRRKAYWEVKFEGIGLGEEYA-TLEGHGAAIDTGTSLIALPSGLAEILNAEIGAKK 322
T++PV AYW++ E + +G +G A +DTGTSLI P+ L+A IG
Sbjct: 248 TFVPVTVPAYWQIHMERVKVGPGLTLCAKGCAAILDTGTSLITGPTEEIRALHAAIGGIP 307
Query: 323 GWSGQYSVDCESRDSLPDLTLNFNGYNFTITAYDYTLEVSGS----CISAFTPMDFPEPV 378
+G+Y + C LP ++ G F +TA+DY ++ + + C+S F +D P P
Sbjct: 308 LLAGEYIILCSEIPKLPAVSFLLGGVWFNLTAHDYVIQTTRNGVRLCLSGFQALDVPPPA 367
Query: 379 GPLAIIGDAFLRKYYSIYDIG----HDAVGLAKA 408
GP I+GD FL Y +++D G VGLA+A
Sbjct: 368 GPFWILGDVFLGTYVAVFDRGDMKSSARVGLARA 401
>7297766 [O] KOG1339 Aspartyl protease
Length = 391
Score = 258 bits (660), Expect = 9e-69
Identities = 144/330 (43%), Positives = 197/330 (59%), Gaps = 16/330 (4%)
Query: 88 LTNYLNAQYFTEITLGSPPQSFKVILDTGSSNLWVPSAEC--GSLACFLHTKYDHEASST 145
L N +N +Y+ I +G+P Q F ++ DTGS+NLWVPSA C + AC H KYD ASST
Sbjct: 68 LHNSMNNEYYGVIAIGTPEQRFNILFDTGSANLWVPSASCPASNTACQRHNKYDSSASST 127
Query: 146 YKANGSEFAIQYGSGSLEGYVSRDLLTIGDLVIPDQDFAEATSEPGLAFAFGKFDGILGL 205
Y ANG EFAI+YG+GSL G++S D++TI + I +Q F EA SEPG F F GILGL
Sbjct: 128 YVANGEEFAIEYGTGSLSGFLSNDIVTIAGISIQNQTFGEALSEPGTTFVDAPFAGILGL 187
Query: 206 AYDSISVNRIVPPVYNAIKNKLLDDPVFAFYLGDSDKSEDGGEASFGGIDEEKYTGEITW 265
A+ +I+V+ + PP N I LLD+PV +FYL + GGE GGID Y G +T+
Sbjct: 188 AFSAIAVDGVTPPFDNMISQGLLDEPVISFYLKRQGTAVRGGELILGGIDSSLYRGSLTY 247
Query: 266 LPVRRKAYWEVKFEGIGLGEEYATL--EGHGAAIDTGTSLIALPSGLAEILNAEIGAKKG 323
+PV AYW+ K I + TL G A DTGTSLIA+P +N ++GA
Sbjct: 248 VPVSVPAYWQFKVNTI---KTNGTLLCNGCQAIADTGTSLIAVPLAAYRKINRQLGATDN 304
Query: 324 WSGQYSVDCESRDSLPDLTLNFNGYNFTITAYDYTLEVSGS----CISAFTPMDFPEPVG 379
G+ V C SLP + LN G FT+ DY ++V+ + C+SAFT M+
Sbjct: 305 -DGEAFVRCGRVSSLPKVNLNIGGTVFTLAPRDYIVKVTQNGQTYCMSAFTYMEGLS--- 360
Query: 380 PLAIIGDAFLRKYYSIYDIGHDAVGLAKAA 409
I+GD F+ K+Y+++D G++ +G A+ A
Sbjct: 361 -FWILGDVFIGKFYTVFDKGNERIGFARVA 389
>CE19495 [O] KOG1339 Aspartyl protease
Length = 398
Score = 258 bits (658), Expect = 1e-68
Identities = 135/354 (38%), Positives = 207/354 (58%), Gaps = 13/354 (3%)
Query: 66 QESFSKDNVDVFVAPEGSHSVPLTNYLNAQYFTEITLGSPPQSFKVILDTGSSNLWVPSA 125
QE V ++ + + + L++Y NAQY+ +T+G+PPQ+F+V+ DTGSSNLWVP A
Sbjct: 39 QEHLKAKYVPGYIPNKDAFNEGLSDYSNAQYYGPVTIGTPPQNFQVLFDTGSSNLWVPCA 98
Query: 126 EC--GSLACFLHTKYDHEASSTYKANGSEFAIQYGSGSLEGYVSRDLLTIGD----LVIP 179
C G +AC +H ++D + SS+ A G+ F IQYG+GS++G V D++ G
Sbjct: 99 NCPFGDIACRMHNRFDCKKSSSCTATGASFEIQYGTGSMKGTVDNDVVCFGHDTTYCTDK 158
Query: 180 DQDFAEATSEPGLAFAFGKFDGILGLAYDSISVNRIVPPVYNAIKNKLL-DDPVFAFYLG 238
+Q A ATSEPG+ F KFDGI G+ +D+ISVN+I P+ N + + +FAF+L
Sbjct: 159 NQGLACATSEPGITFVAAKFDGIFGMGWDTISVNKISQPMDQIFANSAICKNQLFAFWLS 218
Query: 239 -DSDKSEDGGEASFGGIDEEKYTGEITWLPVRRKAYWEVKFEGIGLGEEYATLEGHGAAI 297
D++ +GGE + D Y G I W P+ + YW +K + + T + +
Sbjct: 219 RDANDITNGGEITLCETDPNHYVGNIAWEPLVSEDYWRIKLASVVIDGTTYTSGPIDSIV 278
Query: 298 DTGTSLIALPSGLAEILNAEIGAKKGWSGQYSVDCESRDSLPDLTLNFNGYNFTITAYDY 357
DTGTSL+ P+ + + + +IG ++G+Y V+C SLP++T N G NF + DY
Sbjct: 279 DTGTSLLTGPTDVIKKIQHKIGGIPLFNGEYEVECSKIPSLPNITFNLGGQNFDLQGKDY 338
Query: 358 TLEVS-----GSCISAFTPMDFPEPVGPLAIIGDAFLRKYYSIYDIGHDAVGLA 406
L++S +C+S F MD P P GPL I+GD F+ ++YS++D G+ VG A
Sbjct: 339 ILQMSNGNGGSTCLSGFMGMDIPAPAGPLWILGDVFIGRFYSVFDHGNKRVGFA 392
>7296076 [O] KOG1339 Aspartyl protease
Length = 405
Score = 248 bits (634), Expect = 9e-66
Identities = 142/355 (40%), Positives = 198/355 (55%), Gaps = 24/355 (6%)
Query: 72 DNVDVFVAPEGSHSVP-----------LTNYLNAQYFTEITLGSPPQSFKVILDTGSSNL 120
D V +++ P+ + P L N +N Y+ I +G+P Q FKV+ DTGS+NL
Sbjct: 58 DGVPIYMQPDYGYDYPSQTSVDYTSEELGNSMNMYYYGLIGIGTPEQYFKVVFDTGSANL 117
Query: 121 WVPSAEC--GSLACFLHTKYDHEASSTYKANGSEFAIQYGSGSLEGYVSRDLLTIGDLVI 178
WVPSA+C +AC H +Y+ ASST+ ++G F+IQYG+GS+ GY++ D +TI L I
Sbjct: 118 WVPSAQCLATDVACQQHNQYNSSASSTFVSSGQNFSIQYGTGSVSGYLAIDTVTINGLAI 177
Query: 179 PDQDFAEATSEPGLAFAFGKFDGILGLAYDSISVNRIVPPVYNAIKNKLLDDPVFAFYLG 238
+Q F EA S+PG +F FDGILG+ Y I+ + +VPP YN + L+D+PVF FYL
Sbjct: 178 ANQTFGEAVSQPGASFTDVAFDGILGMGYQQIAEDNVVPPFYNLYEEGLIDEPVFGFYLA 237
Query: 239 DSDKSEDGGEASFGGIDEEKYTGEITWLPVRRKAYWEVKFEGIGLGEEYATLEGHGAAID 298
+ + DGG+ + GG D+ GE+T+ PV ++ YW+ I + G A D
Sbjct: 238 RNGSAVDGGQLTLGGTDQNLIAGEMTYTPVTQQGYWQFAVNNITWNGTVIS-SGCQAIAD 296
Query: 299 TGTSLIALPSGLAEILNAEIGAKKGWSGQYSVDCESRDSLPDLTLNFNGYNF----TITA 354
TGTSLIA PS LN IG G Y V C + SLP LT+N G NF ++
Sbjct: 297 TGTSLIAAPSAAYIQLNNLIGGVP-IQGDYYVPCSTVSSLPVLTINIGGTNFYLPPSVYI 355
Query: 355 YDYTLEVSGSCISAFTPMDFPEPVGPLAIIGDAFLRKYYSIYDIGHDAVGLAKAA 409
YT +C+S FT + I+GD FL +YYS +D G + VG A A
Sbjct: 356 QTYTEGNYTTCMSTFTDIG-----TGFWILGDVFLGQYYSEFDFGQNRVGFATLA 405
>7297765 [O] KOG1339 Aspartyl protease
Length = 423
Score = 239 bits (609), Expect = 7e-63
Identities = 140/332 (42%), Positives = 188/332 (56%), Gaps = 23/332 (6%)
Query: 88 LTNYLNAQYFTEITLGSPPQSFKVILDTGSSNLWVPSAECGSL--ACFLHTKYDHEASST 145
L N N +Y + +G+PPQ F + DTGSS+LWVPS +C S AC H KY+ ASS+
Sbjct: 66 LANGFNLEYTIRLCIGTPPQCFNLQFDTGSSDLWVPSVKCSSTNEACQKHNKYNSSASSS 125
Query: 146 YKANGSEFAIQYGSGSLEGYVSRDLLTIGDLVIPDQDFAEATSEPGLAFAFGKFDGILGL 205
+ +G F+IQYGSGSL G++S D + I +VI +Q FAEA EPG AF FDGI+G+
Sbjct: 126 HVEDGKGFSIQYGSGSLSGFLSTDTVDIDGMVIRNQTFAEAIDEPGSAFVNTIFDGIIGM 185
Query: 206 AYDSISVNRIVPPVYNAIKNKLLDDPVFAFYLGDSDKSEDGGEASFGGIDEEKYTGEITW 265
A+ SIS + P N I+ L+ PVF+ YL S+ GGE +GGID Y G I +
Sbjct: 186 AFASIS-GGVTTPFDNIIRQGLVKHPVFSVYLRRDGTSQSGGEVIWGGIDRSIYRGCINY 244
Query: 266 LPVRRKAYWE-----VKFEGIGLGEEYATLEGHGAAIDTGTSLIALPSGLAEILNAEIGA 320
+PV AYW+ VK EGI L G A DTGTSLIA+P + +N + A
Sbjct: 245 VPVSMPAYWQFTANSVKIEGILL------CNGCQAIADTGTSLIAVPLRAYKAINKVLNA 298
Query: 321 KKGWSGQYSVDCESRDSLPDLTLNFNGYNFTITAYDYTLEVSGS-----CISAFTPMDFP 375
G+ VDC S LP++ LN G +T+T DY +V C+S FT +
Sbjct: 299 TDAGDGEAFVDCSSLCRLPNVNLNIGGTTYTLTPKDYIYKVQADNNQTLCLSGFTYLQ-- 356
Query: 376 EPVGPLAIIGDAFLRKYYSIYDIGHDAVGLAK 407
L I+GD FL K Y+++D+G + +G AK
Sbjct: 357 --GNLLWILGDIFLGKVYTVFDVGKERIGFAK 386
>Hs4506475 [O] KOG1339 Aspartyl protease
Length = 406
Score = 235 bits (599), Expect = 1e-61
Identities = 124/333 (37%), Positives = 195/333 (58%), Gaps = 11/333 (3%)
Query: 85 SVPLTNYLNAQYFTEITLGSPPQSFKVILDTGSSNLWVPSAECGSL--ACFLHTKYDHEA 142
SV LTNY++ QY+ EI +G+PPQ+FKV+ DTGSSN+WVPS++C L AC H +D
Sbjct: 75 SVILTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASD 134
Query: 143 SSTYKANGSEFAIQYGSGSLEGYVSRDLLTIGDLVIPDQDFAEATSEPGLAFAFGKFDGI 202
SS+YK NG+E ++Y +G++ G++S+D++T+G + + Q F E T P L F +FDG+
Sbjct: 135 SSSYKHNGTELTLRYSTGTVSGFLSQDIITVGGITV-TQMFGEVTEMPALPFMLAEFDGV 193
Query: 203 LGLAYDSISVNRIVPPVYNAIKNKLLDDPVFAFYLG-DSDKSED-GGEASFGGIDEEKYT 260
+G+ + ++ R+ P N I +L + VF+FY DS+ S+ GG+ GG D + Y
Sbjct: 194 VGMGFIEQAIGRVTPIFDNIISQGVLKEDVFSFYYNRDSENSQSLGGQIVLGGSDPQHYE 253
Query: 261 GEITWLPVRRKAYWEVKFEGIGLGEEYATLE-GHGAAIDTGTSLIALPSGLAEILNAEIG 319
G ++ + + W+++ +G+ +G E G A +DTG S I+ + E L +G
Sbjct: 254 GNFHYINLIKTGVWQIQMKGVSVGSSTLLCEDGCLALVDTGASYISGSTSSIEKLMEALG 313
Query: 320 AKKGWSGQYSVDCESRDSLPDLTLNFNGYNFTITAYDYTLEVSGS----CISAFTPMDFP 375
AKK Y V C +LPD++ + G +T+T+ DY + S S C A MD P
Sbjct: 314 AKKRLF-DYVVKCNEGPTLPDISFHLGGKEYTLTSADYVFQESYSSKKLCTLAIHAMDIP 372
Query: 376 EPVGPLAIIGDAFLRKYYSIYDIGHDAVGLAKA 408
P GP +G F+RK+Y+ +D ++ +G A A
Sbjct: 373 PPTGPTWALGATFIRKFYTEFDRRNNRIGFALA 405
>At1g11910 [O] KOG1339 Aspartyl protease
Length = 506
Score = 234 bits (598), Expect = 1e-61
Identities = 118/252 (46%), Positives = 162/252 (63%), Gaps = 7/252 (2%)
Query: 86 VPLTNYLNAQYFTEITLGSPPQSFKVILDTGSSNLWVPSAECG-SLACFLHTKYDHEASS 144
V L NYL+AQY+ EI +G+PPQ F V+ DTGSSNLWVPS++C SLAC LH KY SS
Sbjct: 72 VVLKNYLDAQYYGEIAIGTPPQKFTVVFDTGSSNLWVPSSKCYFSLACLLHPKYKSSRSS 131
Query: 145 TYKANGSEFAIQYGSGSLEGYVSRDLLTIGDLVIPDQDFAEATSEPGLAFAFGKFDGILG 204
TY+ NG AI YG+G++ G+ S D +T+GDLV+ DQ+F EAT EPG+ F KFDGILG
Sbjct: 132 TYEKNGKAAAIHYGTGAIAGFFSNDAVTVGDLVVKDQEFIEATKEPGITFVVAKFDGILG 191
Query: 205 LAYDSISVNRIVPPVYNAIKNKLLDDPVFAFYLGDSDKSEDGGEASFGGIDEEKYTGEIT 264
L + ISV + P YN +K L+ +PVF+F+L + E+GGE FGG+D + G+ T
Sbjct: 192 LGFQEISVGKAAPVWYNMLKQGLIKEPVFSFWLNRNADEEEGGELVFGGVDPNHFKGKHT 251
Query: 265 WLPVRRKAYWEVKFEGIGLGEEYATL--EGHGAAIDTGTSLIALPSGLAEILNAEIGAKK 322
++PV +K YW+ + +G G A D+GTSL+A P+ + ++N IGA
Sbjct: 252 YVPVTQKGYWQFDMGDVLIGGAPTGFCESGCSAIADSGTSLLAGPTTIITMINHAIGA-- 309
Query: 323 GWSGQYSVDCES 334
+G S C++
Sbjct: 310 --AGVVSQQCKT 319
Score = 70.9 bits (172), Expect = 3e-12
Identities = 33/88 (37%), Positives = 52/88 (58%), Gaps = 4/88 (4%)
Query: 326 GQYSVDCESRDSLPDLTLNFNGYNFTITAYDYTLEVS----GSCISAFTPMDFPEPVGPL 381
G+ +VDC ++P ++L G F + +Y L+V CIS F +D P GPL
Sbjct: 419 GESAVDCAQLSTMPTVSLTIGGKVFDLAPEEYVLKVGEGPVAQCISGFIALDVAPPRGPL 478
Query: 382 AIIGDAFLRKYYSIYDIGHDAVGLAKAA 409
I+GD F+ KY++++D G++ VG A+AA
Sbjct: 479 WILGDVFMGKYHTVFDFGNEQVGFAEAA 506
>At1g62290 [O] KOG1339 Aspartyl protease
Length = 526
Score = 233 bits (595), Expect = 3e-61
Identities = 123/265 (46%), Positives = 163/265 (61%), Gaps = 20/265 (7%)
Query: 86 VPLTNYLNAQYFTEITLGSPPQSFKVILDTGSSNLWVPSAECG-SLACFLHTKYDHEASS 144
VPL NYL+AQY+ EI +G+PPQ F VI DTGSSNLWVPS +C SL+C+ H KY SS
Sbjct: 79 VPLKNYLDAQYYGEIAIGTPPQKFTVIFDTGSSNLWVPSGKCFFSLSCYFHAKYKSSRSS 138
Query: 145 TYKANGSEFAIQYGSGSLEGYVSRDLLTIGDLVIPDQDFAEATSEPGLAFAFGKFDGILG 204
TYK +G AI YGSGS+ G+ S D +T+GDLV+ DQ+F E TSEPGL F KFDG+LG
Sbjct: 139 TYKKSGKRAAIHYGSGSISGFFSYDAVTVGDLVVKDQEFIETTSEPGLTFLVAKFDGLLG 198
Query: 205 LAYDSISVNRIVPPVYNAIKNKLLDDPVFAFYLGDSDKSEDGGEASFGGIDEEKYTGEIT 264
L + I+V P YN +K L+ PVF+F+L KSE+GGE FGG+D + + GE T
Sbjct: 199 LGFQEIAVGNATPVWYNMLKQGLIKRPVFSFWLNRDPKSEEGGEIVFGGVDPKHFRGEHT 258
Query: 265 WLPVRRKAYWEVKFEGIGLGEEYATLEGHG--AAIDTGTSLIALPS-------------G 309
++PV ++ YW+ + + E G G A D+GTSL+A P+
Sbjct: 259 FVPVTQRGYWQFDMGEVLIAGESTGYCGSGCSAIADSGTSLLAGPTVSKYHEFIVLFQLA 318
Query: 310 LAEILNAEIGAKKGWSGQYSVDCES 334
+ ++N IGA SG S C++
Sbjct: 319 VVAMINKAIGA----SGVVSQQCKT 339
Score = 73.6 bits (179), Expect = 5e-13
Identities = 32/88 (36%), Positives = 52/88 (58%), Gaps = 4/88 (4%)
Query: 325 SGQYSVDCESRDSLPDLTLNFNGYNFTITAYDYTLEVS----GSCISAFTPMDFPEPVGP 380
+G+ +VDC +P ++ G F + +Y L++ CIS FT +D P P GP
Sbjct: 438 NGESAVDCSQLSKMPTVSFTIGGKVFDLAPEEYVLKIGEGPVAQCISGFTALDIPPPRGP 497
Query: 381 LAIIGDAFLRKYYSIYDIGHDAVGLAKA 408
L I+GD F+ KY++++D G++ VG A+A
Sbjct: 498 LWILGDVFMGKYHTVFDFGNEQVGFAEA 525
>At4g04460 [O] KOG1339 Aspartyl protease
Length = 508
Score = 231 bits (589), Expect = 1e-60
Identities = 113/257 (43%), Positives = 167/257 (64%), Gaps = 7/257 (2%)
Query: 81 EGSHSVPLTNYLNAQYFTEITLGSPPQSFKVILDTGSSNLWVPSAECG-SLACFLHTKYD 139
E + VPL NYL+AQY+ +IT+G+PPQ F VI DTGSSNLW+PS +C S+AC+ H+KY
Sbjct: 72 ENADMVPLKNYLDAQYYGDITIGTPPQKFTVIFDTGSSNLWIPSTKCYLSVACYFHSKYK 131
Query: 140 HEASSTYKANGSEFAIQYGSGSLEGYVSRDLLTIGDLVIPDQDFAEATSEPGLAFAFGKF 199
SS+Y+ NG +I+YG+G++ GY S D + +GD+V+ +Q+F EATSEPG+ F KF
Sbjct: 132 ASQSSSYRKNGKPASIRYGTGAISGYFSNDDVKVGDIVVKEQEFIEATSEPGITFLLAKF 191
Query: 200 DGILGLAYDSISVNRIVPPVYNAIKNKLLDDPVFAFYLGDSDKSEDGGEASFGGIDEEKY 259
DGILGL + ISV P YN ++ L+ +P+F+F+L + K +GGE FGG+D + +
Sbjct: 192 DGILGLGFKEISVGNSTPVWYNMVEKGLVKEPIFSFWLNRNPKDPEGGEIVFGGVDPKHF 251
Query: 260 TGEITWLPVRRKAYWEVKFEGIGLGEEYA--TLEGHGAAIDTGTSLIALPSGLAEILNAE 317
GE T++PV K YW+ + + + +G A D+GTSL+ PS + ++N
Sbjct: 252 KGEHTFVPVTHKGYWQFDMGDLQIAGKPTGYCAKGCSAIADSGTSLLTGPSTVITMINHA 311
Query: 318 IGAKKGWSGQYSVDCES 334
IGA+ G S +C++
Sbjct: 312 IGAQ----GIVSRECKA 324
Score = 71.2 bits (173), Expect = 3e-12
Identities = 36/87 (41%), Positives = 49/87 (55%), Gaps = 4/87 (4%)
Query: 327 QYSVDCESRDSLPDLTLNFNGYNFTITAYDYTLE----VSGSCISAFTPMDFPEPVGPLA 382
Q +VDC S+P +T + G +F +T DY + V C S FT MD P GPL
Sbjct: 422 QSAVDCGRVSSMPIVTFSIGGRSFDLTPQDYIFKIGEGVESQCTSGFTAMDIAPPRGPLW 481
Query: 383 IIGDAFLRKYYSIYDIGHDAVGLAKAA 409
I+GD F+ Y++++D G VG AKAA
Sbjct: 482 ILGDIFMGPYHTVFDYGKGRVGFAKAA 508
>7300255 [O] KOG1339 Aspartyl protease
Length = 395
Score = 229 bits (585), Expect = 4e-60
Identities = 127/335 (37%), Positives = 187/335 (54%), Gaps = 13/335 (3%)
Query: 82 GSHSVPLTNYLNAQYFTEITLGSPPQSFKVILDTGSSNLWVPSAECG--SLACFLHTKYD 139
G + L N LN +Y I++GSP Q F ++ DTGS+NLWVPSAEC S+AC H +Y+
Sbjct: 67 GGATETLDNRLNLEYAGPISIGSPGQPFNMLFDTGSANLWVPSAECSPKSVACHHHHRYN 126
Query: 140 HEASSTYKANGSEFAIQYGSGSLEGYVSRDLLTIGDLVIPDQDFAEATSEPGLAFAFGKF 199
ASST+ +G F+I YG+GSL G +++D + IG LV+ +Q F AT EPG F F
Sbjct: 127 ASASSTFVPDGRRFSIAYGTGSLSGRLAQDTVAIGQLVVQNQTFGMATHEPGPTFVDTNF 186
Query: 200 DGILGLAYDSISVNRIVPPVYNAIKNKLLDDPVFAFYLGDSDKSEDGGEASFGGIDEEKY 259
GI+GL + I+ I P + +L+D+ VF+FYL + GGE FGG+D+ K+
Sbjct: 187 AGIVGLGFRPIAELGIKPLFESMCDQQLVDECVFSFYLKRNGSERKGGELLFGGVDKTKF 246
Query: 260 TGEITWLPVRRKAYWEVKFEGIGLGEEYATLEGHGAAIDTGTSLIALPSGLAEILNAEIG 319
+G +T++P+ YW+ + I + + A DTGTSL+A P I+N+ +G
Sbjct: 247 SGSLTYVPLTHAGYWQFPLDVIEVAGTRIN-QNRQAIADTGTSLLAAPPREYLIINSLLG 305
Query: 320 AKKGWSGQYSVDCESRDSLPDLTLNFNGYNFTITAYDYTLEV-----SGSCISAFTPMDF 374
+ +Y ++C DSLP++ G F + DY + S C+SAFT MD
Sbjct: 306 GLPTSNNEYLLNCSEIDSLPEIVFIIGGQRFGLQPRDYVMSATNDDGSSICLSAFTLMD- 364
Query: 375 PEPVGPLAIIGDAFLRKYYSIYDIGHDAVGLAKAA 409
I+GD F+ +YY+ +D G +G A AA
Sbjct: 365 ----AEFWILGDVFIGRYYTAFDAGQRRIGFAPAA 395
>7296075 [O] KOG1339 Aspartyl protease
Length = 410
Score = 214 bits (545), Expect = 2e-55
Identities = 127/338 (37%), Positives = 182/338 (53%), Gaps = 16/338 (4%)
Query: 82 GSHSVPLTNYLNAQYFTEITLGSPPQSFKVILDTGSSNLWVPSAEC-GSLA-CFLHTKYD 139
GS L N N +Y+T + G+PPQ KV++DTGS+NLWV S++C S+A C KY+
Sbjct: 76 GSKVATLENLYNTEYYTTLGFGNPPQDLKVLIDTGSANLWVLSSKCPDSVAPCANRIKYN 135
Query: 140 HEASSTYKANGSEFAIQYGSGS------LEGYVSRDLLTIGDLVIPDQDFAEATSEPGLA 193
AS+TY+A + F I YGS S L G+ S+D + I +Q FAE T+ P A
Sbjct: 136 SSASTTYRAINTAFNIAYGSNSEEGPIALSGFQSQDTVNFAGYSIKNQIFAEITNAPETA 195
Query: 194 FAFGKFDGILGLAYDSISVNRIVPPVYNAIKNKLLDDPVFAFYLG-DSDKSEDGGEASFG 252
F + DGILGL + SI++N I PP YN + L++ VF+ YL + + +GGE G
Sbjct: 196 FLKSQLDGILGLGFASIAINSITPPFYNLMAQGLVNRSVFSIYLNRNGTNAINGGELILG 255
Query: 253 GIDEEKYTGEITWLPVRRKAYWEVKFEGIGLGEEYATLEGHGAAIDTGTSLIALPSGLAE 312
G D Y+G +T++PV YW+ L + E A +D GTSLI +P + +
Sbjct: 256 GSDSGLYSGCLTYVPVSSAGYWQFTMTSANL-NGFQFCENCEAILDVGTSLIVVPEQVLD 314
Query: 313 ILNAEIGA--KKGWSGQYSVDCESRDSLPDLTLNFNGYNFTITAYDYTLEVSGSCISAFT 370
+N +G +G + VDC S LPD+ F + + DY L +C+S FT
Sbjct: 315 TINQILGVLNPTASNGVFLVDCSSIGDLPDIVFTVARRKFPLKSSDYVLRYGNTCVSGFT 374
Query: 371 PMDFPEPVGPLAIIGDAFLRKYYSIYDIGHDAVGLAKA 408
M+ L I+G+ FL YY+ YDI + +GLA A
Sbjct: 375 SMN----GNSLLILGEIFLGAYYTTYDIVYKLIGLAPA 408
>CE21681 [O] KOG1339 Aspartyl protease
Length = 396
Score = 206 bits (524), Expect = 5e-53
Identities = 116/336 (34%), Positives = 180/336 (53%), Gaps = 17/336 (5%)
Query: 87 PLTNYLNAQYFTEITLGSPPQSFKVILDTGSSNLWVPSAECGSLAC-------FLHTKYD 139
P +Y + Y ITLG+PPQ V+LDTGSSNLWV A C + AC + K+D
Sbjct: 59 PFVDYFDDFYLGNITLGTPPQPATVVLDTGSSNLWVIDAACKTQACNGYPDSGYTKQKFD 118
Query: 140 HEASSTYKANGSEFAIQYGSGSLEGYVSRDLLTIGDLVIPDQDFAEATSEPGLAFAFGKF 199
S+T+ +F+IQYGSGS GY+ +D+L G L + Q+F +T + F +
Sbjct: 119 TTKSTTFVKETRKFSIQYGSGSCNGYLGKDVLNFGGLTVQSQEFGVSTHLADV-FGYQPV 177
Query: 200 DGILGLAYDSISVNRIVPPVYNAIKNKLLDDPVFAFYLGDS---DKSEDGGEASFGGIDE 256
DGILGL + +++V+++VPP+ N I K LD P+F +L + + GG ++G ID
Sbjct: 178 DGILGLGWPALAVDQVVPPMQNLIAQKQLDAPLFTVWLDRNLQIAQGTPGGLITYGAIDT 237
Query: 257 EKYTGEITWLPVRRKAYWEVKFEGIGLGEEYATLEGHGAAIDTGTSLIALPSGLAEILNA 316
++T++P+ K YW+ + +G Y+ + DTGTS + P+ + +
Sbjct: 238 VNCAKQVTYVPLSAKTYWQFPLDAFAVG-TYSETKKDQVISDTGTSWLGAPNTIVSAIVK 296
Query: 317 EIGAKKGWSGQ-YSVDCESRDSLPDLTLNFNGYNFTITAYDYTLEV---SGSCISAFTPM 372
+ A WS + Y+VDC + + PDL G F + + +Y L++ G C A M
Sbjct: 297 QTKAVFDWSTELYTVDCSTMKTQPDLIFTIGGAQFPVKSVEYVLDLQLGGGKCALAVFSM 356
Query: 373 DFPEPVGPLAIIGDAFLRKYYSIYDIGHDAVGLAKA 408
GP I+GD F+R+Y ++YDIG+ +G A A
Sbjct: 357 G-SGGFGPSWILGDTFIRQYCNVYDIGNGQIGFATA 391
>7290034 [O] KOG1339 Aspartyl protease
Length = 407
Score = 206 bits (524), Expect = 5e-53
Identities = 122/324 (37%), Positives = 178/324 (54%), Gaps = 20/324 (6%)
Query: 88 LTNYLNAQYFTEITLGSPPQSFKVILDTGSSNLWVPSAECGSLACFLHTKYDHEASSTYK 147
L+NY N QY+ I++G+P Q F V DTGSSNLWVP + C S AC H + SSTY
Sbjct: 69 LSNYDNFQYYGNISIGTPGQDFLVQFDTGSSNLWVPGSSCISTACQDHQVFYKNKSSTYV 128
Query: 148 ANGSEFAIQYGSGSLEGYVSRDLLTIGDLVIPDQDFAEATSEPGLAFAFGKFDGILGLAY 207
ANG+ F+I YG+GS+ GY+S D + L I Q F E T+E G F FDGILG+ +
Sbjct: 129 ANGTAFSITYGTGSVSGYLSVDCVGFAGLTIQSQTFGEVTTEQGTNFVDAYFDGILGMGF 188
Query: 208 DSISVNRIVPPVYNAIKNKLLDDPVFAFYLGDSDK-SEDGGEASFGGIDEEKYTGEITWL 266
S++V+ + P N ++ L+ PVF+F+L D+ + GGE GG D Y+G +T++
Sbjct: 189 PSLAVDGVTPTFQNMMQQGLVQSPVFSFFLRDNGSVTFYGGELILGGSDPSLYSGSLTYV 248
Query: 267 PVRRKAYWEVKFEGIGLGEEYATLEGHGAAIDTGTSLIALPSG----LAEILNAEIGAKK 322
V + AYW+ + + I +G + A DTGTSLI P ++++ NA
Sbjct: 249 NVVQAAYWKFQTDYIKVGSTSISTFAQAIA-DTGTSLIIAPQAQYDQISQLFNA------ 301
Query: 323 GWSGQYSVDCESRDSLPDLTLNFNGYNFTITAYDYTLEVSGSCISAFTPMDFPEPVGPLA 382
+ + +C S S PDL +N NG +F I A Y +E C A ++
Sbjct: 302 --NSEGLFECSS-TSYPDLIININGVDFKIPAKYYIIEEEDFCSLAIQSIN-----QDFW 353
Query: 383 IIGDAFLRKYYSIYDIGHDAVGLA 406
I+GD FL + Y+ +D+G+ +G A
Sbjct: 354 IMGDVFLGRIYTEFDVGNQRLGFA 377
>7300253 [O] KOG1339 Aspartyl protease
Length = 465
Score = 201 bits (512), Expect = 1e-51
Identities = 121/337 (35%), Positives = 175/337 (51%), Gaps = 15/337 (4%)
Query: 77 FVAPEGSHSVPLTNYLNAQYFTEITLGSPPQSFKVILDTGSSNLWVPSAECGSLACFLHT 136
F + S + L N N +Y ++ +G+P Q F V+ DTGSSN+WVP C S AC H
Sbjct: 131 FSFAKSSGTATLKNTANMEYTCKMNIGTPKQKFTVLPDTGSSNIWVPGPHCKSKACKKHK 190
Query: 137 KYDHEASSTYKANGSEFAIQYGSGSLEGYVSRDLLTIGDLVIPDQDFAEATSEPGLAFAF 196
+Y SSTY NG FAI YGSGS+ G +++D + I LV+ +Q FA T EPG F
Sbjct: 191 QYHPAKSSTYVKNGKSFAITYGSGSVAGVLAKDTVRIAGLVVTNQTFAMTTKEPGTTFVT 250
Query: 197 GKFDGILGLAYDSISVNRIVPPVYNAIKNKLLDDPVFAFYLGDSDKSEDGGEASFGGIDE 256
FDGILGL Y SI+V+ + V N ++ FA + S GG FG +
Sbjct: 251 SNFDGILGLGYRSIAVDNVKTLVQNMCSEDVITSCKFAICMKGGGSSSRGGAIIFGSSNT 310
Query: 257 EKYTG--EITWLPVRRKAYWEVKFEGIGLGEEYATLEGHGAAIDTGTSLIALPSGLAEIL 314
Y+G T+ PV +K YW+ + I +G + A +D+GTSLI P+ + +
Sbjct: 311 SAYSGSNSYTYTPVTKKGYWQFTLQDIYVGGTKVS-GSVQAIVDSGTSLITAPTAIYNKI 369
Query: 315 NAEIGAKKGWSGQYSVDCESRDSLPDLTLNFNGYNFTITAYDYTLEVSGS-----CISAF 369
N IG + SG+ + C + +PD T G F + L+V + CISA
Sbjct: 370 NKVIGCRATSSGECWMKCAKK--IPDFTFVIAGKKFVVKGNKMKLKVRTNRGRTVCISAV 427
Query: 370 TPMDFPEPVGPLAIIGDAFLRKYYSIYDIGHDAVGLA 406
T + EPV I+GDAF+R + + +D+ ++ +G A
Sbjct: 428 TEVP-DEPV----ILGDAFIRHFCTEFDLANNRIGFA 459
>Hs22063875 [O] KOG1339 Aspartyl protease
Length = 325
Score = 196 bits (499), Expect = 4e-50
Identities = 105/288 (36%), Positives = 156/288 (53%), Gaps = 3/288 (1%)
Query: 123 PSAECGSLACFLHTKYDHEASSTYKANGSEFAIQYGSGSLEGYVSRDLLTIGDLVIPDQD 182
P + L H +++ E SSTY++ +I YG+GS+ G + D + +G + +Q
Sbjct: 40 PQSTAPVLPAANHNRFNPEDSSTYQSTSETVSITYGTGSMTGILGYDTVQVGGISDTNQI 99
Query: 183 FAEATSEPGLAFAFGKFDGILGLAYDSISVNRIVPPVYNAIKNKLLDDPVFAFYLGDSDK 242
F + +EPG + FDGILGLAY SIS + P N L+ +F+ YL D+
Sbjct: 100 FGLSETEPGSFLYYAPFDGILGLAYPSISSSGATPVFDNIWNQGLVSQDLFSVYLSADDQ 159
Query: 243 SEDGGEASFGGIDEEKYTGEITWLPVRRKAYWEVKFEGIGL-GEEYATLEGHGAAIDTGT 301
S G FGGID YTG + W+PV + YW++ + I + GE A EG A +DTGT
Sbjct: 160 S--GSVVIFGGIDSSYYTGSLNWVPVTVEGYWQITVDSITMNGEAIACAEGCQAIVDTGT 217
Query: 302 SLIALPSGLAEILNAEIGAKKGWSGQYSVDCESRDSLPDLTLNFNGYNFTITAYDYTLEV 361
SL+ P+ + ++IGA + G V C + SLPD+ NG + + Y L+
Sbjct: 218 SLLTGPTSPIANIQSDIGASENSDGDMVVSCSAISSLPDIVFTINGVQYPVPPSAYILQS 277
Query: 362 SGSCISAFTPMDFPEPVGPLAIIGDAFLRKYYSIYDIGHDAVGLAKAA 409
GSCIS F M+ P G L I+GD F+R+Y++++D ++ VGLA A
Sbjct: 278 EGSCISGFQGMNLPTESGELWILGDVFIRQYFTVFDRANNQVGLAPVA 325
>Hs22063872 [O] KOG1339 Aspartyl protease
Length = 325
Score = 196 bits (499), Expect = 4e-50
Identities = 105/288 (36%), Positives = 156/288 (53%), Gaps = 3/288 (1%)
Query: 123 PSAECGSLACFLHTKYDHEASSTYKANGSEFAIQYGSGSLEGYVSRDLLTIGDLVIPDQD 182
P + L H +++ E SSTY++ +I YG+GS+ G + D + +G + +Q
Sbjct: 40 PQSTAPVLPAANHNRFNPEDSSTYQSTSETVSITYGTGSMTGILGYDTVQVGGISDTNQI 99
Query: 183 FAEATSEPGLAFAFGKFDGILGLAYDSISVNRIVPPVYNAIKNKLLDDPVFAFYLGDSDK 242
F + +EPG + FDGILGLAY SIS + P N L+ +F+ YL D+
Sbjct: 100 FGLSETEPGSFLYYAPFDGILGLAYPSISSSGATPVFDNIWNQGLVSQDLFSVYLSADDQ 159
Query: 243 SEDGGEASFGGIDEEKYTGEITWLPVRRKAYWEVKFEGIGL-GEEYATLEGHGAAIDTGT 301
S G FGGID YTG + W+PV + YW++ + I + GE A EG A +DTGT
Sbjct: 160 S--GSVVIFGGIDSSYYTGSLNWVPVTVEGYWQITVDSITMNGEAIACAEGCQAIVDTGT 217
Query: 302 SLIALPSGLAEILNAEIGAKKGWSGQYSVDCESRDSLPDLTLNFNGYNFTITAYDYTLEV 361
SL+ P+ + ++IGA + G V C + SLPD+ NG + + Y L+
Sbjct: 218 SLLTGPTSPIANIQSDIGASENSDGDMVVSCSAISSLPDIVFTINGVQYPVPPSAYILQS 277
Query: 362 SGSCISAFTPMDFPEPVGPLAIIGDAFLRKYYSIYDIGHDAVGLAKAA 409
GSCIS F M+ P G L I+GD F+R+Y++++D ++ VGLA A
Sbjct: 278 EGSCISGFQGMNLPTESGELWILGDVFIRQYFTVFDRANNQVGLAPVA 325
>CE04971 [O] KOG1339 Aspartyl protease
Length = 709
Score = 196 bits (497), Expect = 7e-50
Identities = 136/403 (33%), Positives = 195/403 (47%), Gaps = 52/403 (12%)
Query: 54 EKYLNSFQRAYPQESFSKDN-VDVFVAPEGSHSVPLTNYLN----AQYFTEITLGSPPQS 108
E Y N R + KD + F+ + S+ + + Y+N Y IT+G+P Q
Sbjct: 307 EPYRNRLIREGRWVQYRKDREIRRFMMNKQSNDMSVGQYVNDYEDEAYVGNITIGTPQQQ 366
Query: 109 FKVILDTGSSNLWVPSAECGSL---------------------------------ACFLH 135
FKVILDTGSSNLW+P CG+ +CF
Sbjct: 367 FKVILDTGSSNLWIPDITCGTKPENCSTVPACRGIICQFECDDQACCGAGANYTDSCFYQ 426
Query: 136 TKYDHEASSTYKANGSEFAIQYGSGSLEGYVSRDLLTIG-----DLVIPDQDFAEATSEP 190
K+D SS+YK NG F I+YG+GS G++ +D +T G L +P+ F +ATS
Sbjct: 427 NKFDASKSSSYKTNGRNFIIEYGTGSARGFLGQDTITFGGIGEPQLAVPNTVFGQATSLA 486
Query: 191 GLAFAFGKFDGILGLAYDSISVNRIVPPVYNAIKNKLLDDPVFAFYL---GDSDKSEDGG 247
F DGILGLA+ SI+V++I PP NAI L+D P+F +L GD + GG
Sbjct: 487 AF-FEGQPLDGILGLAFKSIAVDQITPPFINAINQNLVDLPLFTVFLEHEGDQN-GVQGG 544
Query: 248 EASFGGIDEEKYTGEITWLPVRRKAYWEVKFEGIGLGEEYATLEGHGAAIDTGTSLIALP 307
++GGID + I + P+ Y++ K IG G Y + +G DTGTSLI P
Sbjct: 545 VYTYGGIDTKNCGPVIAYQPLSSATYYQFKMSAIGSG-SYHSSKGWQVISDTGTSLIGGP 603
Query: 308 SGLAEILNAEIGAK-KGWSGQYSVDCESRDSLPDLTLNFNGYNFTITAYDYTL-EVSGSC 365
+ +GA + G Y + C ++ + D+T+ YN + L + S +C
Sbjct: 604 KAYVSAIADAVGATWRDDYGVYILPCSAKINTLDITIGNQVYNIDSSNTIIPLGDGSNNC 663
Query: 366 ISAFTPMDFPEPVGPLAIIGDAFLRKYYSIYDIGHDAVGLAKA 408
I A P GP I+GD F+R+Y +IYD+G VG AK+
Sbjct: 664 IYAIFPFS-SGGFGPSWILGDPFIRQYCNIYDVGTQRVGFAKS 705
Score = 99.8 bits (247), Expect = 7e-21
Identities = 78/269 (28%), Positives = 120/269 (43%), Gaps = 49/269 (18%)
Query: 83 SHSVPLTNYLNAQYFTEITLGSPPQSFKVILDTGSSNLWVPSAECGSLACFLHTKYDHEA 142
+++ + +Y +A Y +IT+GSPPQ F+VI+DTGSSN W+P + C + A H
Sbjct: 27 AYAAGVDDYEHAGYVGKITVGSPPQEFRVIMDTGSSNFWIPDSTCDTKATSCHKVLPAPN 86
Query: 143 SSTYKAN------------------GSEFA--------IQYGSGSLEGYVSRDLLTIG-- 174
S N +FA YGS S G + D ++ G
Sbjct: 87 YSAIPGNFFPKFGPFQLLTQLLPTSNPKFAQVLPNFNNSSYGSDSASGILGFDTVSFGGI 146
Query: 175 ---DLVIPDQDFAEATSEPGLAFAFGKFDGILGLAYDSISVNRIVPPVYNAIKNKLLDDP 231
L++PD A A DGI+GL + + S I PP NA+ KL+ DP
Sbjct: 147 SESQLIVPDTVVATAED----------IDGIMGLGFLANSQQNIYPPFVNAVGQKLV-DP 195
Query: 232 VFAFYLGDSDKSEDGGEASFGGIDEEKYTGEITWLPVRRKAYWEVKFEGIGLGEEYATLE 291
+F YLG ++ G+ +FGG D + + P+ A ++ + G Y+
Sbjct: 196 IFHVYLG--NRPNRAGQITFGGQDTQNCAKVKQYHPLTTGAAYQFYMTSVSSG-AYSARN 252
Query: 292 GHGAAIDTGTSLI----ALPSGLAEILNA 316
G A DT +S+I A+ +G+A+ A
Sbjct: 253 GWTALSDTASSIIYGPKAIVAGIADAAGA 281
>7296077 [O] KOG1339 Aspartyl protease
Length = 418
Score = 193 bits (491), Expect = 3e-49
Identities = 121/388 (31%), Positives = 194/388 (49%), Gaps = 25/388 (6%)
Query: 41 KDVPFAEHVAQLGEKYLNSF--------QRAYPQESFSKDNVDVFVAPEGSHSVPLTNYL 92
K V H K L+SF ++ P + +V V+ + L N
Sbjct: 31 KSVQLKLHRETNHTKILSSFHNQKLRLKEKLSPTSDLAISSVSVYQTTVSKEN--LINSH 88
Query: 93 NAQYFTEITLGSPP-QSFKVILDTGSSNLWVPSAECGSLACFLHTKYDHEASSTYKANGS 151
N +Y+ G+P Q +++DT S+NL V S+E +C H Y+ S TY+ANGS
Sbjct: 89 NTEYYVTAGFGTPKSQPVTLLVDTASANLLVYSSEFVKQSCLHHDGYNSSESQTYQANGS 148
Query: 152 EFAIQYGSGS-LEGYVSRDLLTIGDLVIPDQDFAEATSEPGLAFAFGKFDGILGLAYDSI 210
F IQ+ S L G +S D T+GDLVI +Q FAE S P FDGI+GL + I
Sbjct: 149 PFQIQFASQEILTGILSTDTFTLGDLVIKNQTFAEINSAPTDMCKRSNFDGIIGLGFSEI 208
Query: 211 SVNRIVPPVYNAIKNKLLDDPVFAFYLG-DSDKSEDGGEASFGGIDEEKYTGEITWLPVR 269
++N + P+ N ++ L+D+P+F+ Y+ ++ + +GG GG D Y+G +T++PV
Sbjct: 209 ALNGVETPLDNILEQGLIDEPIFSLYVNRNASDASNGGVLLLGGSDPTLYSGCLTYVPVS 268
Query: 270 RKAYWEVKFEGIGLGEEYATLEGHGAAIDTGTSLIALPSGLAEILNAEIGAKK--GWSGQ 327
+ +W++ + +G + A D GTSLI +P +I+N ++G K+ G
Sbjct: 269 KVGFWQITVGQVEIGSK-KLCSNCQAIFDMGTSLIIVPCPALKIINKKLGIKETDRKDGV 327
Query: 328 YSVDCESRDSLPDLTLNFNGYNFTITAYDYTLEVSGSCISAFTPM---------DFPEPV 378
Y +DC+ LP + N +FT+ DY L SG+C+S F+ + D E +
Sbjct: 328 YIIDCKKVSHLPKIVFNIGWKDFTLNPSDYILNYSGTCVSGFSSLSDCNGTQTNDDSEDL 387
Query: 379 GPLAIIGDAFLRKYYSIYDIGHDAVGLA 406
+ + GD F ++++D G VG+A
Sbjct: 388 NNIWVFGDVFFGAIFTLFDFGLKLVGMA 415
>CE21685 [O] KOG1339 Aspartyl protease
Length = 829
Score = 189 bits (479), Expect = 8e-48
Identities = 112/341 (32%), Positives = 181/341 (52%), Gaps = 24/341 (7%)
Query: 85 SVPLTNYLNAQYFTEITLGSPPQSFKVILDTGSSNLWVPSAECGSLAC-------FLHTK 137
S P+++Y + Y T+G+PPQ ++LDTGS+N+WV A C ++ C + K
Sbjct: 492 SQPISDYSDEVYLGNFTVGTPPQPVSLVLDTGSANMWVIDASCDNMFCNGWIGSNYTRQK 551
Query: 138 YDHEASSTYKANGSEFAIQYGSGSLEGYVSRDLLTI-GDLVIPDQDFAEATSEPGLAFAF 196
+D SS++ +F+IQYG G GY+ D + + G L I Q+ A ++ + FA
Sbjct: 552 FDTSKSSSFSRENRKFSIQYGKGLCSGYLGTDTVGLGGGLTIRKQELGIA-NKLDVDFAV 610
Query: 197 GKFDGILGLAYDSISVNRIVPPVYNAIKNKLLDDPVFAFYLGDSDKSEDGGEA---SFGG 253
DGI GLA+ +++V++I PP+ N I LD PVF+ +L ++ GG A ++GG
Sbjct: 611 QPMDGIFGLAWPALAVDQITPPMQNLISQ--LDVPVFSVWLDRKIQASHGGSAGMITYGG 668
Query: 254 IDEEKYTGEITWLPVRRKAYWEVKFEGIGLGEEYATLEGHGAAIDTGTSLIALPSGLAEI 313
ID + +T++P+ K YW+ K +G +G Y+ + DTG+S I+ P +
Sbjct: 669 IDTKNCDAGVTYVPLTAKTYWQFKMDGFAVG-TYSQYGYNQVISDTGSSWISAPYAMIND 727
Query: 314 LNAEIGAKKGWSGQ---YSVDCESRDSLPDLTLNFNGYNFTITAYDYTLEV---SGSCIS 367
+ + A W Y+V C + + PDL G F + + +Y L++ G C
Sbjct: 728 IATQTHAT--WDEMNEIYTVKCSTMKTQPDLVFTIGGALFPVKSVEYILDIGLDEGKCAL 785
Query: 368 AFTPMDFPEPVGPLAIIGDAFLRKYYSIYDIGHDAVGLAKA 408
A +P+ GP I+GD F+R+Y +IYDIG+ +G A A
Sbjct: 786 AISPL-MASGFGPSWILGDVFIRQYCNIYDIGNARIGFANA 825
Score = 179 bits (454), Expect = 7e-45
Identities = 98/309 (31%), Positives = 164/309 (52%), Gaps = 20/309 (6%)
Query: 85 SVPLTNYLNAQYFTEITLGSPPQSFKVILDTGSSNLWVPSAECGSLAC-------FLHTK 137
S PL +Y + Y IT+G+PPQ V+LDT S+NLWV A C S AC + K
Sbjct: 57 SQPLIDYYDDMYLANITVGTPPQPASVVLDTASANLWVIDAACNSQACNGNPGSGYTKQK 116
Query: 138 YDHEASSTYKANGSEFAIQYGSGSLEGYVSRDLLTIGDLVIPDQDFAEATSEPGLAFAFG 197
++ SST+ F+IQYGSG+ GY+ D+L +G L + Q+F AT+ G
Sbjct: 117 FNPNKSSTFVKGTRRFSIQYGSGTSSGYLGTDVLQLGGLTVKAQEFGVATN-LGSVLGSE 175
Query: 198 KFDGILGLAYDSISVNRIVPPVYNAIKNKLLDDPVFAFYLG---DSDKSEDGGEASFGGI 254
DGI GL + +ISV+++ PP+ N I K LD P+F+ ++ + GG ++G +
Sbjct: 176 PMDGIFGLGWPAISVDQVTPPMQNLISQKQLDAPLFSIWVDRKLQVSQGGTGGLITYGAV 235
Query: 255 DEEKYTGEITWLPVRRKAYWEVKFEGIGLGEEYATLEGHGAAIDTGTSLIALPSGLAEIL 314
D + ++ ++ + K YW+ +G+ +G YA ++ A DTG++ + LP+ + +
Sbjct: 236 DTKNCDAQVNYVALSSKTYWQFPMDGVAIG-NYAMMKQEQAISDTGSAWLGLPNPVLNAI 294
Query: 315 NAEIGAKKGWSGQ-YSVDCESRDSLPDLTLNFNGYNFTITAYDYTLEV---SGSCISA-- 368
+ A W+ + Y++DC + + PDL G + + + +Y L++ +G C+ A
Sbjct: 295 VQQTKATYDWNYEIYTLDCSTMQTQPDLVFTIGGMQYPVKSIEYILDLGLGNGRCVLAIK 354
Query: 369 --FTPMDFP 375
F +FP
Sbjct: 355 LFFGKFEFP 363
>CE20430 [O] KOG1339 Aspartyl protease
Length = 638
Score = 187 bits (476), Expect = 2e-47
Identities = 112/339 (33%), Positives = 175/339 (51%), Gaps = 19/339 (5%)
Query: 85 SVPLTNYLNAQYFTEITLGSPPQSFKVILDTGSSNLWVPSAECGSLAC------FLHTKY 138
S PL + + IT+GSPPQS V +DT S+NLWV + C S+ C + K+
Sbjct: 51 SQPLLGFSDDPCIGNITIGSPPQSAFVFMDTTSANLWVMGSACTSVNCNDPLLGIIKHKF 110
Query: 139 DHEASSTYKANGSEFAIQYGSGSLEGYVSRDLLTIGDLVIPDQDFAEATSEPGLAFAFGK 198
+ S+++ + +F IQYGSG GY+ D + IG L I Q+F A + + FG
Sbjct: 111 NTTKSTSFVKSNRKFNIQYGSGECSGYLGTDTVEIGGLKIQKQEFGVANI---VDYDFGT 167
Query: 199 --FDGILGLAYDSISVNRIVPPVYNAIKNKLLDDPVFAFYLGDSDKS---EDGGEASFGG 253
DGI GLA+ ++SV+++ PP+ N + LD P+F + D G ++GG
Sbjct: 168 RPIDGIFGLAWPALSVDQVTPPMQNLVSQNQLDAPIFTIFFDKRDPDYYYPSNGLITYGG 227
Query: 254 IDEEKYTGEITWLPVRRKAYWEVKFEGIGLGEEYATLEGHGAAIDTGTSLIALP-SGLAE 312
+D + I+++PV K YW+ K +G +G T+ A +DTG+S LP S +A
Sbjct: 228 LDTKNCNANISYVPVSSKTYWQFKVDGFQVGTYNRTVNRDQAIMDTGSSWFGLPYSVIAG 287
Query: 313 ILNAEIGAKKGWSGQYSVDCESRDSLPDLTLNFNGYNFTITAYDYTLEV---SGSCISAF 369
I ++ Y+V C + +SLPDL F I+A +Y +V G+C A
Sbjct: 288 IATQTNATWDLYASVYTVPCSTMNSLPDLVFTIGAEKFPISAPEYVEDVGLDDGTCALAM 347
Query: 370 TPMDFPEPVGPLAIIGDAFLRKYYSIYDIGHDAVGLAKA 408
+D GP +G+ F+R+Y S++D+G+ +G A A
Sbjct: 348 YGID-ASGFGPSVTLGNIFIRRYCSVFDVGNARIGFADA 385
Score = 97.4 bits (241), Expect = 3e-20
Identities = 56/184 (30%), Positives = 96/184 (51%), Gaps = 11/184 (5%)
Query: 100 ITLGSPPQSFKVILDTGSSNLWVPSAECGSLACFLHT-----KYDHEASSTYKANGSEFA 154
IT+G+PPQS V +DT S+N WV ++C S C ++ K++ S+++ F+
Sbjct: 458 ITIGTPPQSASVFMDTTSANWWVIGSKCTSANCNGYSGIRKHKFNTTKSTSFVEGNRTFS 517
Query: 155 IQYGSGSLEGYVSRDLLTIGDLVIPDQDFAEATSEPGLAFAFGKFDGILGLAYDSISVNR 214
+YG + GY+ D + +G L I Q+ AT GL F + GI LA+ ++SV++
Sbjct: 518 TEYGLCT--GYLGTDTVQMGGLTITKQELGIATIV-GLGFGLKPYVGIFELAWPALSVDQ 574
Query: 215 IVPPVYNAIKNKLLDDPVFAFYLGDSDKSEDGGEA---SFGGIDEEKYTGEITWLPVRRK 271
+ PP+ I LD P+F +L D+ G ++GG D + +T++ + K
Sbjct: 575 VTPPMQKLISQNQLDAPMFTIWLDQKDQGVYVGYTGLITYGGFDNKNCDANVTYVALSSK 634
Query: 272 AYWE 275
+W+
Sbjct: 635 TFWQ 638
>CE16843 [O] KOG1339 Aspartyl protease
Length = 394
Score = 183 bits (465), Expect = 4e-46
Identities = 117/341 (34%), Positives = 174/341 (50%), Gaps = 18/341 (5%)
Query: 81 EGSHSVPLTNYLNAQYFTEITLGSP-----PQSFKVILDTGSSNLWVPSAECG----SLA 131
+G H + ++ + YF ITLG+P Q+F V+LDTGSSN+WVP CG A
Sbjct: 52 KGQHQ-HVADFRDFAYFGNITLGTPIESTAEQTFLVVLDTGSSNVWVPDNSCGIDDKKSA 110
Query: 132 CFLHTKYDHEASSTYKANGSEFAIQYGSGSLEGYVSRDLLTIGD--LVIPDQDFAEATSE 189
C KY SS+Y+ +G+ F+I YG+GS GY +D L D L I Q F +A +
Sbjct: 111 CTYKKKYFGTDSSSYEKDGTPFSISYGTGSASGYFGKDTLCFSDTTLCIKSQIFGQANNI 170
Query: 190 PGLAFAFGKFDGILGLAYDSISVNRIVPPVYNAIKNKLLDDPVFAFYLGDSD--KSEDGG 247
FA + DGILGL + ++V+ + PP NA++ L+D+P+F YL K GG
Sbjct: 171 APF-FANQEIDGILGLGFTDLAVHSVPPPFVNAVEQGLVDEPIFTVYLEHHGIKKEASGG 229
Query: 248 EASFGGIDEEKYTGEITWLPVRRKAYWEVKFEGIGLGEEYATLEGHGAAIDTGTSLIALP 307
++GG D + ITW+P+ + AYW+ + +GIG+ G DTGTS I P
Sbjct: 230 YFTYGGEDPDHCGEIITWIPLTKAAYWQFRMQGIGIDNVNEHKNGWEVISDTGTSFIGGP 289
Query: 308 SGLAEILNAEIGAK-KGWSGQYSVDCESRDSLPDLTLNFNGYNFTITAYDYTLEV-SGSC 365
+ + + + GA +S Y + C +L L + N F I + S C
Sbjct: 290 GKVIQDIANKYGATYDEYSDSYVIPCSEIKNLRSLKMKINDLTFEIDPINLVAHPDSSEC 349
Query: 366 ISAFTPMDFPEPVGPLAIIGDAFLRKYYSIYDIGHDAVGLA 406
M + GP I+GD F+R++ +I+DI + +GLA
Sbjct: 350 DLTLFDM-YGGGFGPSWILGDPFIRQFCNIHDIKNKRIGLA 389
>CE09542 [O] KOG1339 Aspartyl protease
Length = 389
Score = 183 bits (465), Expect = 4e-46
Identities = 117/340 (34%), Positives = 181/340 (52%), Gaps = 17/340 (5%)
Query: 78 VAPEGSHSVP--LTNYLNAQYFTEITLGSPPQSFKVILDTGSSNLWVPSAECGSLACFLH 135
V+P ++P + ++ + +Y IT+G+P Q F V+LDTGSSNLW+P C C
Sbjct: 51 VSPNVLANLPQNVNDFGDFEYLGNITIGTPDQGFIVVLDTGSSNLWIPGPTC-KTNCKTK 109
Query: 136 TKYDHEASSTYKANGSEFAIQYGSGSLEGYVSRDLLTIG-----DLVIPDQDFAEATSEP 190
+K+D ASST+ NG + IQYGSG G + +D + G L +P F A S+
Sbjct: 110 SKFDSTASSTFVKNGKSWTIQYGSGDAAGILGQDTVRFGAKGDSQLSVPTTTFGIA-SKI 168
Query: 191 GLAFAFGKFDGILGLAYDSISVNRIVPPVYNAIKNKLLDDPVFAFYLGDSDKSED--GGE 248
F DGILGLA+ S++V+ +VPP+ NAI +LD P+F+ +L + + GG
Sbjct: 169 SADFKNDATDGILGLAFTSLAVDGVVPPLINAINQGILDQPLFSVWLEHRGAANNVGGGV 228
Query: 249 ASFGGIDEEKYTGEITWLPVRRKAYWEVKFEGIGLGEEYATLEGHGAAIDTGTSLIALPS 308
++G ID + + P+ Y++ K G LG Y+ + DTGTS + P
Sbjct: 229 FTYGAIDTTNCGALVAYQPLSSATYYQFKAAGFKLG-SYSNTKTVDVISDTGTSFLGGPQ 287
Query: 309 GLAEILNAEIGAK-KGWSGQYSVDCESRDSLPDLTLNFNGYNFTITAYDYTLEV-SGSCI 366
+ + L GA ++ Y +DC ++ D+T+ N Y +I +Y ++ +G C+
Sbjct: 288 SVVDGLAKAAGATYDDFNEVYFIDCAAQPGTLDITIGTNTY--SIQPVNYIVDAGNGQCL 345
Query: 367 SAFTPMDFPEPVGPLAIIGDAFLRKYYSIYDIGHDAVGLA 406
A P DF GP I+GD F+R+Y +IYDIG+ +G A
Sbjct: 346 FAAFPFDF-GGFGPSWILGDPFIRQYCNIYDIGNKRMGFA 384
>CE09540 [O] KOG1339 Aspartyl protease
Length = 395
Score = 180 bits (457), Expect = 3e-45
Identities = 111/329 (33%), Positives = 171/329 (51%), Gaps = 12/329 (3%)
Query: 88 LTNYLNAQYFTEITLGSPPQSFKVILDTGSSNLWVPSAECGSLACFLHTKYDHEASSTYK 147
+ ++ + +Y IT+G+PPQ F V+LDTGS+NLWVP + C C +++D S+T+K
Sbjct: 65 VNDFGDVEYLGNITIGTPPQQFIVVLDTGSANLWVPGSNCDG-TCKGKSEFDSSKSTTFK 123
Query: 148 ANGSEFAIQYGSGSLEGYVSRDLLTIG-----DLVIPDQDFAEATSEPGLAFAFGKFDGI 202
NG + IQY SGS +G + D + G L++P F A S F +GI
Sbjct: 124 KNGQSWQIQYESGSAKGIMGVDTVAFGGASEQQLLVPSTTFGIA-SHISSNFKNDAAEGI 182
Query: 203 LGLAYDSISVNRIVPPVYNAIKNKLLDDPVFAFYL--GDSDKSEDGGEASFGGIDEEKYT 260
LGLA+ S++V+ + PP+ NAI K+LD P+F +L + K+ GG ++G +D
Sbjct: 183 LGLAFTSLAVDGVTPPLINAINKKILDQPLFTVFLEHKGTAKNVGGGVFTYGAVDTTNCG 242
Query: 261 GEITWLPVRRKAYWEVKFEGIGLGEEYATLEGHGAAIDTGTSLIALPSGLAEILNAEIGA 320
I + P+ Y++ +G LG Y+ + DTG+SLI PS + +GA
Sbjct: 243 PVIAYQPLSSATYYQFVADGFKLG-SYSNNKKSQVISDTGSSLIGGPSAVINGFAQALGA 301
Query: 321 K-KGWSGQYSVDCESRDSLPDLTLNFNGYNFTITAYDYTLEVSGSCISAFTPMDFPEPVG 379
K Y + C + D+T+ N Y+ Y + + +C+ A DF G
Sbjct: 302 KYHSDDDAYYLPCSTSKGTLDITIGGNVYSIEPVNYILDVGMGDTCVFAAFSFDF-GGFG 360
Query: 380 PLAIIGDAFLRKYYSIYDIGHDAVGLAKA 408
P I GD F+R+Y +IYDIG +G AK+
Sbjct: 361 PSWIFGDPFIRQYCNIYDIGQQRIGFAKS 389
>CE09539 [O] KOG1339 Aspartyl protease
Length = 393
Score = 178 bits (451), Expect = 1e-44
Identities = 117/355 (32%), Positives = 178/355 (49%), Gaps = 16/355 (4%)
Query: 63 AYPQESFSKDNVDVFVAPEGSHSVPLTNYLNAQYFTEITLGSPPQSFKVILDTGSSNLWV 122
AY Q + + D V +V ++ + +Y IT+G+PPQ F V+LDTGSSNLWV
Sbjct: 42 AYVQHKAALRDADPAVYANAPQNV--NDFGDFEYLGNITIGTPPQPFLVVLDTGSSNLWV 99
Query: 123 PSAECGSLACFLHTKYDHEASSTYKANGSEFAIQYGSGSLEGYVSRDLLTIG-----DLV 177
P C +C +Y SST+KANG + IQYGSG+ +GY+ D + G L
Sbjct: 100 PGPSCDG-SCKGKREYQSTKSSTFKANGKPWQIQYGSGNAKGYLGEDTVAFGAVTEKQLP 158
Query: 178 IPDQDFAEATSEPGLAFAFGKFDGILGLAYDSISVNRIVPPVYNAIKNKLLDDPVFAFYL 237
+P F AT F +GILGLA+ S++V+ +VPP+ NAI LLD P+F +L
Sbjct: 159 VPSTTFGIAT-HISSDFKNDAAEGILGLAFTSLAVDHVVPPLINAINQGLLDQPLFTVWL 217
Query: 238 GDSDKSED--GGEASFGGIDEEKYTGEITWLPVRRKAYWEVKFEGIGLGEEYATLEGHGA 295
+ D GG ++G +D I + P+ Y++ + LG Y+ + +
Sbjct: 218 EHKGSANDVGGGVFTYGAVDTTNCGPVIAYQPLSSATYYQFVADSFKLG-SYSNSKKYQV 276
Query: 296 AIDTGTSLIALPSGLAEILNAEIGAK-KGWSGQYSVDCESRDSLPDLTLNFNGYNFTITA 354
DTGTS + P + L + +GA Y V C + D+T+ Y+
Sbjct: 277 ISDTGTSFLGGPKAVVAGLASALGATYHSNDDSYYVPCATNIGTLDITIGGKVYSINPVN 336
Query: 355 YDYTLEVSGSCI-SAFTPMDFPEPVGPLAIIGDAFLRKYYSIYDIGHDAVGLAKA 408
Y + + +C+ +AF +F GP I+GD F+R++ +IYDIG +G A +
Sbjct: 337 YIVDVGMGDTCVFAAFAFNNF--GFGPAWILGDPFIRQFCNIYDIGGQRMGFANS 389
>7300254 [O] KOG1339 Aspartyl protease
Length = 309
Score = 177 bits (450), Expect = 2e-44
Identities = 109/320 (34%), Positives = 172/320 (53%), Gaps = 19/320 (5%)
Query: 95 QYFTEITLGSPPQSFKVILDTGSSNLWVPSAEC--GSLACFLHTKYDHEASSTYKANGSE 152
+Y+ I +G+P Q+F VI DTGSSN W+PS C + AC H KY+ SS+Y +G
Sbjct: 2 EYYGTIAMGNPRQNFTVIFDTGSSNTWLPSVNCPMSNSACQNHRKYNSSRSSSYIPDGRN 61
Query: 153 FAIQYGSGSLEGYVSRDLLTIGDLVIPDQDFAEATSEPGLAFAFGKFDGILGLAYDSISV 212
F ++YGSG + GY+S+D + I +P F E+ AF+ KFDG++GL +S
Sbjct: 62 FTLRYGSGMVVGYLSKDTMHIAGAELPHFTFGESLFLQHFAFSSVKFDGLVGLGLGVLSW 121
Query: 213 NRIVPPVYNAIKNKLLDDPVFAFYLGDSDKSEDGGEASFGGIDEEKYTGEITWLPVRRKA 272
+ P + +LL+ VF+ YL D E FGG DE K+ G++ ++PV +
Sbjct: 122 SNTTPFLELLCAQRLLEKCVFSVYL-----RRDPREIVFGGFDESKFEGKLHYVPVSQWH 176
Query: 273 YWEVKFEGIGLGEEYATLEGHGAAIDTGTSLIALPSGLAEILNAEIGAKKGWSGQYSVDC 332
W ++ +G + + + A +DTGTSL+ +P L + AK +G + V C
Sbjct: 177 TWSLQISKSSVGTKQIGGKSN-AILDTGTSLVLVPQQTYHNLLNTLSAKL-QNGYFVVAC 234
Query: 333 ESRDSLPDLTLNFNGYNFTITAYDYTLEV----SGSCISAFTPMDFPEPVGPLAIIGDAF 388
+S SLP++ + F +T+ DY +EV +C+ A P++ ++GD F
Sbjct: 235 KS-GSLPNINILIGDKVFPLTSSDYIMEVLLDRKPACVLAIAPIN-----RGFWVLGDIF 288
Query: 389 LRKYYSIYDIGHDAVGLAKA 408
LR+YY+++D +GLAKA
Sbjct: 289 LRRYYTVFDATEKRIGLAKA 308
>7296074 [O] KOG1339 Aspartyl protease
Length = 393
Score = 164 bits (414), Expect = 3e-40
Identities = 116/368 (31%), Positives = 182/368 (48%), Gaps = 23/368 (6%)
Query: 50 AQLGEKYLNSFQRAYPQESFSKDNVDVFVAPEGSHSV---PLTNYLNAQYFTEITLGSPP 106
A L ++ N+ +R Y N + G V PL N + +F +++G
Sbjct: 39 AHLHLQFRNALRRKYGFTPLRTVNAVNVTSESGKGVVITEPLINSYDTNFFGVVSVGD-- 96
Query: 107 QSFKVILDTGSSNLWVPSAECGSLACFLHTKYDHEASS-TYKANGSEFAIQYGSGSLEGY 165
QSF + DTGSS+ WVPS+ C K+ +++S +++++G+ F+I YGSGS++G
Sbjct: 97 QSFTMQFDTGSSDFWVPSSHCRFCIKTCGNKFFRKSNSKSFRSSGTPFSITYGSGSVKGI 156
Query: 166 VSRDLLTIGDLVIPDQDFAEATSEPGLAFAFGKFDGILGLAYDSISVNRIVPPVYNAIKN 225
V+ D + GDL I +Q ++ + FDGI G A+ +S+ + VP I
Sbjct: 157 VASDNVGFGDLKIQNQGIGLV----NISDSCSVFDGIAGFAFQQLSMTKSVPSFQQMIDQ 212
Query: 226 KLLDDPVFAFYLGDSDKSEDGGEASFGGIDEEKYTGEITWLPVRRKAYWEVKFEGI---G 282
+L++ P+F+F+L S DGG GG + Y G +T+ V YW K + I G
Sbjct: 213 QLVEQPIFSFHL--KSGSSDGGSMILGGSNSSLYYGPLTYTNVTEAKYWSFKLDFIAVHG 270
Query: 283 LGEEYATLEGHGAAIDTGTSLIALPSGLAEILNAEIGAKKGWS-GQYSVDCESRDSLPDL 341
G ++ G+ A +DTGTSLI P +N +IGA+ + Y+V CES LP +
Sbjct: 271 KGSR-SSRTGNKAIMDTGTSLIVGPVLEVLYINKDIGAEHNKTYNLYTVACESIPQLPII 329
Query: 342 TLNFNGYNFTITAYDYTLEVSGSCISAFTPMDFPEPVG-PLAIIGDAFLRKYYSIYDIGH 400
G F + + Y + C SAF M +G I+GDAF+R+ Y +D
Sbjct: 330 VFGIAGKEFFVKPHTYVIRYDNFCFSAFMDM-----LGLQYWILGDAFMRENYVEFDWAR 384
Query: 401 DAVGLAKA 408
+G+A A
Sbjct: 385 RRMGIAPA 392
>CE11478 [O] KOG1339 Aspartyl protease
Length = 383
Score = 161 bits (408), Expect = 1e-39
Identities = 109/332 (32%), Positives = 166/332 (49%), Gaps = 21/332 (6%)
Query: 90 NYLNAQYFTEITLGSPPQSFKVILDTGSSNLWVPSAECGSLAC-----FLHTKYDHEASS 144
++ + Y + +G+P Q F+V LDT SSNLWV EC S +C +Y+ ASS
Sbjct: 56 DHFDEYYTVSVRIGTPAQHFEVALDTTSSNLWVFGVECKSQSCQVLKYIRIREYNRTASS 115
Query: 145 TYKANGSEFAIQYGSGSLEGYVSRDLLTIGDLVIPDQDFAEATSEPGLAFAFGKFDGILG 204
T+ A S F + + G + G + +D + I +QDF T L+ FDG+LG
Sbjct: 116 TFIAGTSNFVLPFNDGDVSGDLGKDNIQFAGSKIQNQDFGIGTDATRLSGV--TFDGVLG 173
Query: 205 LAYDSISVNRIVPPVYNAIKNKLLDDPVFAFYLGDSD--KSEDGGEASFGGIDEEKYTGE 262
L + + ++N + N + LD P+F Y S GGE +FG ID +
Sbjct: 174 LGWPATALNGTSTTMQNLLPQ--LDQPLFTTYFTKSSVHNGTVGGEITFGAIDTTHCQSQ 231
Query: 263 ITWLPVRRKAYWEVKFEGIGLGEEYATLEGHGAAIDTGTSLIALPS-GLAEILNAEIGAK 321
I ++ + + W +G G Y+ + A DT +S +P+ LAEI+ A GA+
Sbjct: 232 INYVRLAYDSLWSYSIDGFSFG-NYSRNQTDTAIPDTTSSYTGVPNLVLAEIVIA-TGAQ 289
Query: 322 KGWSGQ-YSVDCESRDSLPDLTLNFNGYNFTITAYDYTLEV---SGSC-ISAFTPMDFPE 376
W+ Q Y++ C S +LPDL G ++ + A +Y + + +G C +S F F
Sbjct: 290 YDWNHQAYTLPCSSTATLPDLVFTIGGNSYNVRAVEYVVNLNLPNGQCALSLFG--TFSS 347
Query: 377 PVGPLAIIGDAFLRKYYSIYDIGHDAVGLAKA 408
P GPL + GD FLR Y I+D G+ +GLAKA
Sbjct: 348 PSGPLWVFGDNFLRSYCHIFDFGNSRIGLAKA 379
>CE21684 [O] KOG1339 Aspartyl protease
Length = 435
Score = 157 bits (397), Expect = 3e-38
Identities = 93/303 (30%), Positives = 162/303 (52%), Gaps = 24/303 (7%)
Query: 83 SHSVPLTNYLNAQYFTEITLGSPPQSFKVILDTGSSNLWVPSAECGSLAC-----FLHTK 137
S ++PL +Y++ Y IT+G+PPQS V++ TGS+N WV A C S AC HTK
Sbjct: 52 SGALPLADYMDEIYTANITVGTPPQSASVVMGTGSANFWVVGAGCTSPACNGFPDSGHTK 111
Query: 138 ---YDHEASSTYKANGSEFAIQYGSGSLEGYVSRDLLTIGDLVIPDQDFAEATSEPGLAF 194
Y +++SS N +F I Y +G+ GY+ D+L +G L + +Q+FA T ++
Sbjct: 112 LKFYSNKSSSFVDLN-RKFFINYPTGACSGYLGTDVLQLGGLTVKNQEFAVTTQ---ISD 167
Query: 195 AFGKF--DGILGLAYDSISVNRIVPPVYNAIKNKLLDDPVFAFYLG---DSDKSEDGGEA 249
G F DG+LGLA+ ++V++I PP+ N + LD P+F +L + GG
Sbjct: 168 QMGHFPLDGVLGLAWPPVAVDQITPPMQNLMPQ--LDAPIFTLWLDRVLQGSQGGSGGLI 225
Query: 250 SFGGIDEEKYTGEITWLPVRRKAYWEVKFEGIGLGEEYATLEGHGAAIDTGTSLIALPSG 309
+FG ID + ++ ++ + K +W+ +G+ +G Y +++ A D+G + LP
Sbjct: 226 TFGAIDTKNCDAQVNYVALSSKTFWQFPLDGVAIG-SYTSMKKDQAISDSGDFGLRLPLA 284
Query: 310 LAEILNAEIGAKKGWSGQ-YSVDCESRDSLPDLTLNFNGYNFTITAYDYTLEV---SGSC 365
+ + + A W+ + Y++DC + + PDL G + + + +Y L++ +G C
Sbjct: 285 VLNAVIQQTKATYDWTNEFYTLDCSTMQTQPDLVFTIGGMQYPVKSVEYILDLGLGNGRC 344
Query: 366 ISA 368
+ A
Sbjct: 345 VLA 347
>CE05287 [O] KOG1339 Aspartyl protease
Length = 428
Score = 155 bits (391), Expect = 1e-37
Identities = 106/372 (28%), Positives = 173/372 (46%), Gaps = 51/372 (13%)
Query: 83 SHSVPLTNYLNAQYFTEITLGSPPQSFKVILDTGSSNLWVPS--------AECGSL---- 130
S S P+ +Y + Y +I+LGSP Q+F + +D+GSSNLWVP A CGS
Sbjct: 59 SSSSPVIDYEDMAYMVQISLGSPAQNFVLFIDSGSSNLWVPDITCAGGKDATCGSYCKST 118
Query: 131 ----------------------------ACFLHTKYDHEASSTYKANGSEFAIQYGSGSL 162
AC +++ SS+Y NG +F + Y +G +
Sbjct: 119 PYDACLTFCQEECCTKTVEGVKVLSTTDACQSKHRFNSSLSSSYVTNGQKFDMTYNTGEV 178
Query: 163 EGYVSRDLL--TIGDLVIPDQDFAEATSEPGLAFAFGKFDGILGLAYDSISVNRIVPPVY 220
+G+ D T + Q F +AT+ G AFA DGI+GL + +++VN+ PP++
Sbjct: 179 KGFFGVDTFCFTNTSVCATGQVFGQATTI-GEAFAKQPEDGIIGLGWPALAVNQQTPPLF 237
Query: 221 NAIKNKLLDDPVFAFYLGDSDKSE--DGGEASFGGIDEEKYTGEITWLPVRRKAYWEVKF 278
N + LD P F YL + + +GG + GG+D + + W+P+ + +W+ K
Sbjct: 238 NLMNQGKLDQPYFVVYLANIGPTSQINGGAFTVGGLDTTHCSSNVDWVPLSTQTFWQFKL 297
Query: 279 EGIGLGE-EYATLEGHGAAIDTGTSLIALPSGLAEILNAEIGAK-KGWSGQYSVDCESRD 336
G+ G A G AA DT S I P + L +GA +G + +DC++
Sbjct: 298 GGVSSGSYSQAPNSGWQAAADTAASFIGAPKSVVTSLAKAVGATYVPLTGAFFMDCDA-- 355
Query: 337 SLPDLTLNFNGYNFTITAYDYTLEVS-GSCISAFTPMDFPEPVGPLAIIGDAFLRKYYSI 395
+PD+ NG + + + + + G C+ AF + P ++G F+R Y +
Sbjct: 356 VVPDIVFTINGKTYNMPSTSFVVSAGPGPCMFAFYELT-AGGFYPAWMLGPPFMRAYCHV 414
Query: 396 YDIGHDAVGLAK 407
+D+ +GLAK
Sbjct: 415 HDMKSGRLGLAK 426
>CE11480 [O] KOG1339 Aspartyl protease
Length = 474
Score = 153 bits (386), Expect = 5e-37
Identities = 100/337 (29%), Positives = 160/337 (46%), Gaps = 21/337 (6%)
Query: 85 SVPLTNYLNAQYFTEITLGSPPQSFKVILDTGSSNLWVPSAECGSLACF-----LHTKYD 139
+V ++ + Y + +G+P Q F+V DT SSNLWV EC S C +Y+
Sbjct: 142 NVSFFDHFDEYYTAGVRIGTPAQHFQVAFDTTSSNLWVFGVECRSQNCHGGRGRRDREYN 201
Query: 140 HEASSTYKANGSEFAIQYGSGSLEGYVSRDLLTIGDLVIPDQDFAEATSEPGLAFAFGK- 198
ASST+ A S F + Y G + G V +D I QDF T+ L FG+
Sbjct: 202 RTASSTFVAGTSSFNLPYDGGHVSGNVGKDTAQFAGFTIQSQDFGIGTAATRL---FGET 258
Query: 199 FDGILGLAYDSISVNRIVPPVYNAIKNKLLDDPVFAFYLGDSD--KSEDGGEASFGGIDE 256
FDG+LGL + + ++N + N + LD +F Y S+ GG+ FG ID
Sbjct: 259 FDGVLGLGWPATALNGTSTTMQNLLPQ--LDQKLFTTYFTKSNMHNGTAGGDIMFGAIDT 316
Query: 257 EKYTGEITWLPVRRKAYWEVKFEGIGLGEEYATLEGHGAAIDTGTSLIALPSGLAEILNA 316
++ ++P+ ++W +G +G Y+ + DT + +P+ + +
Sbjct: 317 THCQSQVNYVPLAYNSFWSYSVDGFSIG-TYSRTQTETTIPDTSSGWTGVPNVVLAGIVK 375
Query: 317 EIGAKKGWSGQ-YSVDCESRDSLPDLTLNFNGYNFTITAYDYTLEV---SGSC-ISAFTP 371
GA W+ Q Y++ C S +LPD+ G ++ + A +Y + + +G C +S F
Sbjct: 376 ATGATYDWNHQAYTLPCSSTATLPDMVFTIGGNSYNVRAVEYVVNLNLPNGQCALSLFGT 435
Query: 372 MDFPEPVGPLAIIGDAFLRKYYSIYDIGHDAVGLAKA 408
GP I+GD FLR Y ++D G+ +GLAKA
Sbjct: 436 A--ASQSGPAWILGDNFLRSYCHVFDFGNSRIGLAKA 470
>CE21683 [O] KOG1339 Aspartyl protease
Length = 320
Score = 152 bits (384), Expect = 9e-37
Identities = 91/269 (33%), Positives = 147/269 (53%), Gaps = 17/269 (6%)
Query: 85 SVPLTNYLNAQYFTEITLGSPPQSFKVILDTGSSNLWVPSAECGSLAC-------FLHTK 137
S P +Y++ Y I++G+P Q+ ++LDTGSSNLWV A C S AC F K
Sbjct: 58 SQPFIDYMDDFYLGNISVGTPGQTLTLVLDTGSSNLWVIDAACNSEACNGDPKSGFAKHK 117
Query: 138 YDHEASSTYKANGSEFAIQYGSGSLEGYVSRDLLTIGDLVIPDQDFAEATSEPGLAFAFG 197
+D +ASST+ + +F+I YGSGS G+++RD +T+G L I +Q+F A + + FA
Sbjct: 118 FDTKASSTFVSETRKFSISYGSGSCSGHLARDTITMGGLKIDNQEFGVAETLASV-FAEQ 176
Query: 198 KFDGILGLAYDSISVNRIVPPVYNAIKNKLLDDPVFAFYLGDSDKSEDGGEA---SFGGI 254
DGILGL + +++ +++ PP+ N + LD VF ++ + +GG ++G +
Sbjct: 177 PVDGILGLGWPALADDKVTPPMQNLLPQ--LDAKVFTVWMDRKLQGSNGGNGGLITYGAL 234
Query: 255 DEEKYTGEITWLPVRRKAYWEVKFEGIGLGEEYATLEGHGAAIDTGTSLIALPSGLAEIL 314
D +I+++P+ K YWE +G +G ++ + DTGTS I P + +
Sbjct: 235 DSVNCADDISYVPLTAKTYWEFALDGFAVG-SFSETKTAKVISDTGTSWIGAPHSIISAV 293
Query: 315 NAEIGAKKGWSGQ-YSVDCESRDSLPDLT 342
GAK W+ + Y V C + P+LT
Sbjct: 294 VKATGAKFEWTTELYVVPCSTMK--PNLT 320
>CE09738 [O] KOG1339 Aspartyl protease
Length = 389
Score = 150 bits (380), Expect = 3e-36
Identities = 99/325 (30%), Positives = 168/325 (51%), Gaps = 15/325 (4%)
Query: 89 TNYLNAQYFTEITLGSPPQSFKVILDTGSSNLWVPSAECGSLACFLHTKYDHEASSTYKA 148
T+Y+ +Y IT+G+P Q+F V+LDTGS+NL +P C + C ++ +ASSTY A
Sbjct: 65 TDYVYYEYMGNITVGTPDQNFIVVLDTGSANLLIPGTNC-TTYCEKKRLFNEKASSTYIA 123
Query: 149 NGSEFAIQYGSGSLEGYVSRDLLTIG-----DLVIPDQDFAEATSEPGLAFAFGKFDGIL 203
+ I+Y SG G + D + IG L IP + + G F + +GI
Sbjct: 124 TNRPWQIKYASGDAYGTLGIDTVKIGGSGEAQLAIP-RSYLGVADTVGSDFKWSPKEGIF 182
Query: 204 GLAYDSISVNRIVPPVYNAIKNKLLDDPVFAFYLGD--SDKSEDGGEASFGGIDEEKYTG 261
GLA+ +++V+ I PP+ NAI LLD P+F + G + + G ++GG+D+
Sbjct: 183 GLAFTALAVDNITPPIINAINQGLLDQPLFTTWFGQRGAPGTSASGAFTYGGLDKNHCGP 242
Query: 262 EITWLPVRRKAYWEVKFEGIGLGEEYATLEGHGAAIDTGTSLIALPSGLAEILNAEIGAK 321
I + + +++ + G LG Y + + DT TS + P + L GA
Sbjct: 243 VIGYAELTNARHFQFQATGFSLG-SYVSTTTYEVITDTATSFLCGPQAAIDNLAKAAGAT 301
Query: 322 KGWSGQ-YSVDCESRDSLPDLTLNFNGYNFTITAYDYTLEV-SGSCISAFTPMDFPEPVG 379
+ Q +++ C++ D+ P + + +N+ I A +Y L++ + SC+ A P ++ G
Sbjct: 302 WDPTNQVFNIPCDA-DAGP-IKMKIGQFNYVIRANNYILKIDTNSCLFAAIPQNY-AGFG 358
Query: 380 PLAIIGDAFLRKYYSIYDIGHDAVG 404
P I+G F+R+Y +++DIG VG
Sbjct: 359 PSWILGGPFMRQYCNVHDIGQKRVG 383
>YLR121c [O] KOG1339 Aspartyl protease
Length = 508
Score = 131 bits (330), Expect = 2e-30
Identities = 114/401 (28%), Positives = 182/401 (44%), Gaps = 53/401 (13%)
Query: 49 VAQLGEKYLNSFQRAYPQESFSK---------DNVDVFVAPEGSHSVPLTNYLNAQYFTE 99
VA L +F R P + K DN ++ G L N + Y E
Sbjct: 8 VATLAVLTSPAFGRVLPDGKYVKIPFTKKKNGDNGELSKRSNGHEKFVLANE-QSFYSVE 66
Query: 100 ITLGSPPQSFKVILDTGSSNLWVP---SAECGS-LACFLHTKYDHEASSTYKAN-GSEFA 154
+ +G+P Q+ V+LDTGS++LWVP + CGS + C + +D SST+KAN S F
Sbjct: 67 LAIGTPSQNLTVLLDTGSADLWVPGKGNPYCGSVMDCDQYGVFDKTKSSTFKANKSSPFY 126
Query: 155 IQYGSGS-LEGYVSRDLLTIGDLVIPDQDFAEATSEPGLAFAFGKFDGILGLAYDSISVN 213
YG G+ EG +D L +L + FA A +E F G+LG+ ++ V
Sbjct: 127 AAYGDGTYAEGAFGQDKLKYNELDLSGLSFAVA-NESNSTF------GVLGIGLSTLEVT 179
Query: 214 RIVPPVYNAIKNKLLDD-PVF----------AFYLGDSDKSEDGGEASFGGIDEEKYTGE 262
++ D+ P+F A+ L +D+S+ G FG +D KY G+
Sbjct: 180 YSGKVAIMDKRSYEYDNFPLFLKHSGAIDATAYSLFLNDESQSSGSILFGAVDHSKYEGQ 239
Query: 263 ITWLPV---------RRKAYWEVKFEGIGLGEE----YATLEGHGAAIDTGTSLIALPSG 309
+ +P+ + ++V +G+GL + T A +D+GT+L LPS
Sbjct: 240 LYTIPLVNLYKSQGYQHPVAFDVTLQGLGLQTDKRNITLTTTKLPALLDSGTTLTYLPSQ 299
Query: 310 LAEILNAEIGAKKGWS-GQYSVDCESRDSLPDLTLNFNGYNFTITAYDYTLEVS-GSCIS 367
+L + A + G Y C S D+ + +F G+ D+T++ S G+C+
Sbjct: 300 AVALLAKSLNASYSKTLGYYEYTCPSSDNKTSVAFDFGGFRINAPLSDFTMQTSVGTCVL 359
Query: 368 AFTPMDFPEPVGPLAIIGDAFLRKYYSIYDIGHDAVGLAKA 408
A P+ AI+GD+FLR Y +YD+ + + LA+A
Sbjct: 360 AI----IPQAGNATAILGDSFLRNAYVVYDLDNYEISLAQA 396
>At1g69100 [O] KOG1339 Aspartyl protease
Length = 343
Score = 128 bits (321), Expect = 2e-29
Identities = 93/330 (28%), Positives = 155/330 (46%), Gaps = 35/330 (10%)
Query: 88 LTNYLNAQYFTEITLGSPPQSFKVILDTGSSNLWVPSAECGSLACFLHTKYDHEASSTYK 147
L N+ ++ EI++GSPPQ F V+ DTGS++LWVPS E H K+D +AS T +
Sbjct: 39 LKNFDGVVFYGEISVGSPPQKFNVVFDTGSTDLWVPSKEWPEETDHKHPKFDKDASKTCR 98
Query: 148 -ANGSEFAIQYGSGSLEGYVSRDLLTIGDLVIPDQDFAEATSEPGLAFAFGKFDGILGLA 206
G E I Y +GS+ G +++D + +G +VI QD A + P F KFDG++GL
Sbjct: 99 LMKGGEVNIAYETGSVVGILAQDNVNVGGVVIKSQDLFLARN-PDTYFRSVKFDGVIGLG 157
Query: 207 YDSISVNRIVPPVYNAIKNKLLDDPVFAFYLGDSDKSEDGGEASFGGIDEEKYTGEITWL 266
S V GD + +GG+ FGG D +++ GE ++
Sbjct: 158 IKSSRAQGSV--------------------TGDGGEDPNGGQIMFGGFDPKQFKGEHVYV 197
Query: 267 PVR-RKAYWEVKFEGIGLGEE----YATLEGHGAAIDTGTSLIALPSGLAEILNAEIGAK 321
P++ W++K I + + + A +D+G++ I P + EIGA
Sbjct: 198 PMKLSDDRWKIKMSKIYINGKPAINFCDDVECTAMVDSGSTDIFGPDEAVGKIYKEIGAT 257
Query: 322 KGWSGQYSVDCESRDSLPDLTLNFNGYNFTITAYDYTLEVSGSCISAFTPMDFPEPVGPL 381
K + CE +LPD+ G + +T +DY + + +
Sbjct: 258 K-----VIIRCEQFPALPDIYFEIGGKHLRLTKHDYVEVKTNPKKRCRLRIVKSKNRRKD 312
Query: 382 AIIGDAFLRKYYSIYDIGH---DAVGLAKA 408
++G+AF+ K+++++D G +G A+A
Sbjct: 313 WVLGEAFMTKFHTVFDYGDVKTPRIGFAEA 342
>Hs22063919 [O] KOG1339 Aspartyl protease
Length = 267
Score = 125 bits (313), Expect = 1e-28
Identities = 63/176 (35%), Positives = 95/176 (53%), Gaps = 2/176 (1%)
Query: 230 DPVFAFYLGDSDKSEDGGEAS-FGGIDEEKYTGEITWLPVRRKAYWEVKFEGIGL-GEEY 287
D F G S+ + G FGGID YTG + W+PV + YW++ + I + GE
Sbjct: 88 DFTVVFDTGSSNLDDQSGSVVIFGGIDSSYYTGSLNWVPVTVEGYWQITVDSITMNGEAI 147
Query: 288 ATLEGHGAAIDTGTSLIALPSGLAEILNAEIGAKKGWSGQYSVDCESRDSLPDLTLNFNG 347
A EG A +DTGTSL+ P+ + ++IGA + G V C + SLPD+ NG
Sbjct: 148 ACAEGCQAIVDTGTSLLTGPTSPIANIQSDIGASENSDGDMVVSCSAISSLPDIVFTING 207
Query: 348 YNFTITAYDYTLEVSGSCISAFTPMDFPEPVGPLAIIGDAFLRKYYSIYDIGHDAV 403
+ + Y L+ GSCIS F M+ P G L I+GD F+R+Y++++D ++ +
Sbjct: 208 VQYPVPPSAYILQSEGSCISGFQGMNLPTESGELWILGDVFIRQYFTVFDRANNQI 263
>At4g22050 [O] KOG1339 Aspartyl protease
Length = 336
Score = 124 bits (312), Expect = 2e-28
Identities = 98/331 (29%), Positives = 161/331 (48%), Gaps = 40/331 (12%)
Query: 86 VPLTNYLNAQYFTEITLGSPPQSFKVILDTGSSNLWVPSAECGSLACFLHTKYDHEASST 145
V L N + Y+ +I +G+P Q+F V+ DTGSS+LWVPS + +Y AS T
Sbjct: 36 VQLKNVKDFLYYGKIQIGNPGQTFTVLFDTGSSSLWVPSENWLAKTENPRNRYISSASRT 95
Query: 146 YKANGSEFAIQYGSGSLEGYVSRDLLTIGDLVIPDQDFAEATSEPGLAFAFGK--FDGIL 203
+K NG++ ++YG GSL G++S D +T+G + I Q F E P F F K FDGIL
Sbjct: 96 FKENGTKAELKYGKGSLTGFLSVDTVTVGGISITSQTFIEGVKTPYKEF-FKKMPFDGIL 154
Query: 204 GLAYDSISVNRIVPPVYNAIKNKLLDDPVFAFYLGDSDKSED--GGEASFGGIDEEKYTG 261
GL + +N ++ + + VF+ +L S + GGE FGGI ++G
Sbjct: 155 GLRFTD-PLNFGTSVWHSMVFQGKIAKNVFSIWLRRFSNSGEINGGEVVFGGIIPAHFSG 213
Query: 262 EITWLPVRRKA-YWEVKFEGIGLGEEYATLEGHGAAIDTGTSLIALPSGLAEILNAEIGA 320
+ T++ V ++ + +G G A +D+G+S I +P A+ ++ IG
Sbjct: 214 DHTYVDVEGPGNFFAMSNIWVGGKNTNICSSGCKAIVDSGSSNINVPMDSADEIHRYIGV 273
Query: 321 KKGWSGQYSVDCESRDSLPDLTLNFNGYNFTITAYDYTLEVSGSCISAFTPMDFPEPVGP 380
+ +C + ++LPD+T G F +T L+VSG+
Sbjct: 274 EP--------NCNNFETLPDVTFTIGGKAFVLT----PLDVSGT---------------- 305
Query: 381 LAIIGDAFLRKYYSIYDIGHD---AVGLAKA 408
+G F+R +++++D + VG AK+
Sbjct: 306 --TLGIPFMRVFHTVFDYQNTLAVKVGFAKS 334
>CE09541 [O] KOG1339 Aspartyl protease
Length = 350
Score = 118 bits (295), Expect = 2e-26
Identities = 95/328 (28%), Positives = 156/328 (46%), Gaps = 58/328 (17%)
Query: 88 LTNYLNAQYFTEITLGSPPQSFKVILDTG-----SSNLWVPSAECGSLACFLHTKYDHEA 142
+ ++ + +Y IT+G+P QSF V+LDT ++NL T+Y
Sbjct: 64 VNDFADFEYLGNITIGTPDQSFIVVLDTEQIVSRNTNL---------------TRYCEAT 108
Query: 143 SSTYKANGSEFAIQYGSGSLEGYVSRDLLTIGDLVIPDQDFAEATSEPGLAFAFGKFDGI 202
++ AI + + VS DL +AT DGI
Sbjct: 109 GE------NQLAIPKTTFGIANQVSADLKN------------DAT------------DGI 138
Query: 203 LGLAYDSISVNRIVPPVYNAIKNKLLDDPVFAFYLGDSD--KSEDGGEASFGGIDEEKYT 260
GLA+ +++V+ +VPP+ NAIK +LD P+F+ +L + GG ++G +D
Sbjct: 139 FGLAFTTLAVDGVVPPLINAIKQGILDQPLFSVFLEHRGTLTNVGGGVFTYGAVDTTNCE 198
Query: 261 GEITWLPVRRKAYWEVKFEGIGLGEEYATLEGHGAAIDTGTSLIALPSGLAEILNAEIGA 320
I + P+ Y++ K LG +Y + DTGTS + PS + + + GA
Sbjct: 199 PVIGYQPLSSATYFQFKANRFRLG-KYLNAKVVDVISDTGTSFLGGPSVVINEIAKQAGA 257
Query: 321 KKGWSGQ-YSVDCESRDSLPDLTLNFNGYNFTITAYDYTLEV-SGSCISAFTPMDFPEPV 378
G+ Y +DC++ ++T+ G+++ I Y+Y +V G+C+ A PMDF
Sbjct: 258 TYYILGEAYVIDCDATPGPLEVTI--GGHDYQIEHYNYIADVGDGTCVMALFPMDF-GGF 314
Query: 379 GPLAIIGDAFLRKYYSIYDIGHDAVGLA 406
GP I+GD F+R+Y +IYDIG+ +G A
Sbjct: 315 GPSWILGDPFIRQYCNIYDIGNFRMGFA 342
>Hs22050827 [O] KOG1339 Aspartyl protease
Length = 160
Score = 108 bits (271), Expect = 1e-23
Identities = 51/94 (54%), Positives = 71/94 (75%), Gaps = 2/94 (2%)
Query: 85 SVPLTNYLNAQYFTEITLGSPPQSFKVILDTGSSNLWVPSAECG--SLACFLHTKYDHEA 142
SVPL+ +L+AQYF EI LG+PPQ+F V DTGSSNLWVPS C S+ C+ H +++ A
Sbjct: 67 SVPLSKFLDAQYFGEIGLGTPPQNFTVAFDTGSSNLWVPSRRCHFFSVPCWFHHRFNPNA 126
Query: 143 SSTYKANGSEFAIQYGSGSLEGYVSRDLLTIGDL 176
SS++K +G++FAIQYG+G ++G +S D LT+ L
Sbjct: 127 SSSFKPSGTKFAIQYGTGRVDGILSEDKLTVSGL 160
>YLR120c [O] KOG1339 Aspartyl protease
Length = 569
Score = 99.4 bits (246), Expect = 9e-21
Identities = 80/323 (24%), Positives = 143/323 (43%), Gaps = 44/323 (13%)
Query: 115 TGSSNLWVPSAECGSLACFLHTKYDHEASSTYKANGSEFAIQYGSGSL-EGYVSRDLLTI 173
+G++ VP++E ++ C + + SST+++N + F+I YG G+ G D+L +
Sbjct: 170 SGTATQSVPASEA-TMDCQQYGTFSTSGSSTFRSNNTYFSISYGDGTFASGTFGTDVLDL 228
Query: 174 GDLVIPDQDFAEATSEPGLAFAFGKFDGILGLAYDSISVNRIVPPVYNA----------- 222
DL + FA A G+LG+ + V ++
Sbjct: 229 SDLNVTGLSFAVANETNSTM-------GVLGIGLPELEVTYSGSTASHSGKAYKYDNFPI 281
Query: 223 -IKNK-LLDDPVFAFYLGDSDKSEDGGEASFGGIDEEKYTGEITWLPV---------RRK 271
+KN + ++ YL DSD G FG +D KYTG + +P+
Sbjct: 282 VLKNSGAIKSNTYSLYLNDSDAMH--GTILFGAVDHSKYTGTLYTIPIVNTLSASGFSSP 339
Query: 272 AYWEVKFEGIGLGE-----EYATLEGHGAAIDTGTSLIALPSGLAEILNAEIGAK-KGWS 325
++V GIG+ + + T A +D+GT+L LP + ++ E+GA+
Sbjct: 340 IQFDVTINGIGISDSGSSNKTLTTTKIPALLDSGTTLTYLPQTVVSMIATELGAQYSSRI 399
Query: 326 GQYSVDCESRDSLPDLTLNFNGYNFTITAYDYTLEVSGSCISAFTPMDFPEPVGPLAIIG 385
G Y +DC S DS+ ++ +F G++ + L +C+ P + G I+G
Sbjct: 400 GYYVLDCPSDDSM-EIVFDFGGFHINAPLSSFILSTGTTCLLGIIPTS--DDTG--TILG 454
Query: 386 DAFLRKYYSIYDIGHDAVGLAKA 408
D+FL Y +YD+ + + +A+A
Sbjct: 455 DSFLTNAYVVYDLENLEISMAQA 477
>Hs21040360 [O] KOG1339 Aspartyl protease
Length = 468
Score = 97.4 bits (241), Expect = 3e-20
Identities = 76/292 (26%), Positives = 141/292 (48%), Gaps = 36/292 (12%)
Query: 96 YFTEITLGSPPQSFKVILDTGSSNLWVPSAECGSLACFLHTKYDHEASSTYKANGSEFAI 155
Y+ E+ +G+PPQ ++++DTGSSN A G+ ++ T +D E SSTY++ G + +
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNF----AVAGTPHSYIDTYFDTERSSTYRSKGFDVTV 147
Query: 156 QYGSGSLEGYVSRDLLTIGD-------LVIPDQDFAEATSEPGLAFAFGKFDGILGLAYD 208
+Y GS G+V DL+TI + I +E PG+ K++GILGLAY
Sbjct: 148 KYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATIFESENFFLPGI-----KWNGILGLAYA 202
Query: 209 SIS-VNRIVPPVYNAIKNKLLDDPVFAFY-----LGDSDKSEDGGEASFGGIDEEKYTGE 262
+++ + + ++++ + VF+ L + +GG GGI+ Y G+
Sbjct: 203 TLAKPSSSLETFFDSLVTQANIPNVFSMQMCGAGLPVAGSGTNGGSLVLGGIEPSLYKGD 262
Query: 263 ITWLPVRRKAYWEVKFEGIGLGEEYATLE-----GHGAAIDTGTSLIALPSGLAEILNAE 317
I + P++ + Y++++ + +G + L+ A +D+GT+L+ LP ++ +A
Sbjct: 263 IWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNADKAIVDSGTTLLRLPQ---KVFDAV 319
Query: 318 IGAKKGWSGQYSVDCESRDSLPDLTLNFNGYNFTITAYDYTLEVSGSCISAF 369
+ A S Y + LN+ Y F I+ L + + + F
Sbjct: 320 VEAVARASLLYI------QPMMGAGLNYECYRFGISPSTNALVIGATVMEGF 365
>Hs6912266 [O] KOG1339 Aspartyl protease
Length = 501
Score = 96.7 bits (239), Expect = 6e-20
Identities = 91/349 (26%), Positives = 148/349 (42%), Gaps = 39/349 (11%)
Query: 96 YFTEITLGSPPQSFKVILDTGSSNLWVPSAECGSLACFLHTKYDHEASSTYKANGSEFAI 155
Y+ E+T+GSPPQ+ +++DTGSSN V +A FLH Y + SSTY+ +
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAP----HPFLHRYYQRQLSSTYRDLRKGVYV 130
Query: 156 QYGSGSLEGYVSRDLLTI--GDLVIPDQDFAEATSEPGLAFAFGKFDGILGLAYDSIS-V 212
Y G EG + DL++I G V + A T ++GILGLAY I+
Sbjct: 131 PYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIARP 190
Query: 213 NRIVPPVYNAIKNKLLDDPVFA-------FYLGDSD-KSEDGGEASFGGIDEEKYTGEIT 264
+ + P ++++ + +F+ F L S+ + GG GGID YTG +
Sbjct: 191 DDSLEPFFDSLVKQTHVPNLFSLQLCGAGFPLNQSEVLASVGGSMIIGGIDHSLYTGSLW 250
Query: 265 WLPVRRKAYWE-----VKFEGIGLGEEYATLEGHGAAIDTGTSLIALPSGLAEILNAEIG 319
+ P+RR+ Y+E V+ G L + + +D+GT+ + LP + E I
Sbjct: 251 YTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEAAVKSIK 310
Query: 320 AKKG--------WSGQYSVDCESRDS----LPDLTLNFNG------YNFTITAYDYTLEV 361
A W G+ V ++ + P ++L G + TI Y V
Sbjct: 311 AASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRITILPQQYLRPV 370
Query: 362 SGSCISAFTPMDFP-EPVGPLAIIGDAFLRKYYSIYDIGHDAVGLAKAA 409
S F ++G + +Y ++D +G A +A
Sbjct: 371 EDVATSQDDCYKFAISQSSTGTVMGAVIMEGFYVVFDRARKRIGFAVSA 419
>Hs21040362 [O] KOG1339 Aspartyl protease
Length = 396
Score = 96.3 bits (238), Expect = 7e-20
Identities = 65/230 (28%), Positives = 120/230 (51%), Gaps = 27/230 (11%)
Query: 96 YFTEITLGSPPQSFKVILDTGSSNLWVPSAECGSLACFLHTKYDHEASSTYKANGSEFAI 155
Y+ E+ +G+PPQ ++++DTGSSN A G+ ++ T +D E SSTY++ G + +
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNF----AVAGTPHSYIDTYFDTERSSTYRSKGFDVTV 147
Query: 156 QYGSGSLEGYVSRDLLTIGD-------LVIPDQDFAEATSEPGLAFAFGKFDGILGLAYD 208
+Y GS G+V DL+TI + I +E PG+ K++GILGLAY
Sbjct: 148 KYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATIFESENFFLPGI-----KWNGILGLAYA 202
Query: 209 SIS-VNRIVPPVYNAIKNKLLDDPVFAFY-----LGDSDKSEDGGEASFGGIDEEKYTGE 262
+++ + + ++++ + VF+ L + +GG GGI+ Y G+
Sbjct: 203 TLAKPSSSLETFFDSLVTQANIPNVFSMQMCGAGLPVAGSGTNGGSLVLGGIEPSLYKGD 262
Query: 263 ITWLPVRRKAYWEVKFEGIGLGEEYATLE-----GHGAAIDTGTSLIALP 307
I + P++ + Y++++ + +G + L+ A +D+GT+L+ LP
Sbjct: 263 IWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNADKAIVDSGTTLLRLP 312
>Hs19923395 [O] KOG1339 Aspartyl protease
Length = 518
Score = 96.3 bits (238), Expect = 7e-20
Identities = 65/230 (28%), Positives = 120/230 (51%), Gaps = 27/230 (11%)
Query: 96 YFTEITLGSPPQSFKVILDTGSSNLWVPSAECGSLACFLHTKYDHEASSTYKANGSEFAI 155
Y+ E+ +G+PPQ ++++DTGSSN A G+ ++ T +D E SSTY++ G + +
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNF----AVAGTPHSYIDTYFDTERSSTYRSKGFDVTV 147
Query: 156 QYGSGSLEGYVSRDLLTIGD-------LVIPDQDFAEATSEPGLAFAFGKFDGILGLAYD 208
+Y GS G+V DL+TI + I +E PG+ K++GILGLAY
Sbjct: 148 KYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATIFESENFFLPGI-----KWNGILGLAYA 202
Query: 209 SIS-VNRIVPPVYNAIKNKLLDDPVFAFY-----LGDSDKSEDGGEASFGGIDEEKYTGE 262
+++ + + ++++ + VF+ L + +GG GGI+ Y G+
Sbjct: 203 TLAKPSSSLETFFDSLVTQANIPNVFSMQMCGAGLPVAGSGTNGGSLVLGGIEPSLYKGD 262
Query: 263 ITWLPVRRKAYWEVKFEGIGLGEEYATLE-----GHGAAIDTGTSLIALP 307
I + P++ + Y++++ + +G + L+ A +D+GT+L+ LP
Sbjct: 263 IWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNADKAIVDSGTTLLRLP 312
>Hs21040366 [O] KOG1339 Aspartyl protease
Length = 476
Score = 94.0 bits (232), Expect = 4e-19
Identities = 88/340 (25%), Positives = 141/340 (40%), Gaps = 46/340 (13%)
Query: 96 YFTEITLGSPPQSFKVILDTGSSNLWVPSAECGSLACFLHTKYDHEASSTYKANGSEFAI 155
Y+ E+T+GSPPQ+ +++DTGSSN V +A FLH Y + SSTY+ +
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAP----HPFLHRYYQRQLSSTYRDLRKGVYV 130
Query: 156 QYGSGSLEGYVSRDLLTI--GDLVIPDQDFAEATSEPGLAFAFGKFDGILGLAYDSISVN 213
Y G EG + DL++I G V + A T ++GILGLAY I+
Sbjct: 131 PYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIA-- 188
Query: 214 RIVPPVYNAIKNKLLDDPVFAFYLGDSDKSEDGGEASFGGIDEEKYTGEITWLPVRRKAY 273
R+ + ++++L + GG GGID YTG + + P+RR+ Y
Sbjct: 189 RLCGAGFPLNQSEVL--------------ASVGGSMIIGGIDHSLYTGSLWYTPIRREWY 234
Query: 274 WE-----VKFEGIGLGEEYATLEGHGAAIDTGTSLIALPSGLAEILNAEIGAKKG----- 323
+E V+ G L + + +D+GT+ + LP + E I A
Sbjct: 235 YEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEAAVKSIKAASSTEKFP 294
Query: 324 ---WSGQYSVDCESRDS----LPDLTLNFNG------YNFTITAYDYTLEVSGSCISAFT 370
W G+ V ++ + P ++L G + TI Y V S
Sbjct: 295 DGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRITILPQQYLRPVEDVATSQDD 354
Query: 371 PMDFP-EPVGPLAIIGDAFLRKYYSIYDIGHDAVGLAKAA 409
F ++G + +Y ++D +G A +A
Sbjct: 355 CYKFAISQSSTGTVMGAVIMEGFYVVFDRARKRIGFAVSA 394
>YDR144c [O] KOG1339 Aspartyl protease
Length = 596
Score = 87.4 bits (215), Expect = 3e-17
Identities = 101/441 (22%), Positives = 176/441 (39%), Gaps = 99/441 (22%)
Query: 54 EKYLNSFQRAYPQESFSKDNVDVFVAPEGSHSVPLTNYLNAQYFTEITLGSPPQSFKVIL 113
+KY +SF+ A +K + + V LTN N+ Y E+ +G+PPQ V++
Sbjct: 43 KKYGSSFENALDD---TKGRTRLMTRDDDYELVELTNQ-NSFYSVELDIGTPPQKVTVLV 98
Query: 114 D--------TGSSNLWVPSAE---CGS--------------------------------- 129
D TGS N + + + GS
Sbjct: 99 DTGSSDLWVTGSDNPYCSTKKKDTTGSSFKQVNKDALASVVESVFTEISYDTTIVTSEAT 158
Query: 130 ------------LACFLHTKYDHEASSTYKANGSEFAIQYGSGSL-EGYVSRDLLTIGDL 176
+ C + ++ SST+ +N +EF+I YG + G D L++ DL
Sbjct: 159 ATFDSTASTSQLIDCATYGTFNTSKSSTFNSNNTEFSIAYGDTTFASGTWGHDQLSLNDL 218
Query: 177 VIPDQDFAEATSEPGLAFAFGKFDGILGL--AYDSISVNRIVPP-VYN----AIKNK-LL 228
I FA A G G+ GL Y +S++ + YN +KN ++
Sbjct: 219 NITGLSFAVANETNSTVGVLGI--GLPGLESTYSGVSLSSVQKSYTYNNFPMVLKNSGVI 276
Query: 229 DDPVFAFYLGDSDKSEDGGEASFGGIDEEKYTGEITWLPV----RRKAY-----WEVKFE 279
++ + DSD G FG +D KY G++ +P+ + + Y ++V +
Sbjct: 277 KSTAYSLFANDSDSKH--GTILFGAVDHGKYAGDLYTIPIINTLQHRGYKDPIQFQVTLQ 334
Query: 280 GIGLGE-------EYATLEGHGAAIDTGTSLIALPSGLAEILNAEIGAKKGWS-GQYSVD 331
G+G + T +D+GT++ +P+ L ++L ++GA + G Y +D
Sbjct: 335 GLGTSKGDKEDNLTTLTTTKIPVLLDSGTTISYMPTELVKMLADQVGATYSSAYGYYIMD 394
Query: 332 C-ESRDSLPDLTLNFNGYNFTITAYDYTLEV---SGSCISAFTPMDFPEPVGPLAIIGDA 387
C + + + +F G+ + D+ L S CI P P I+GD
Sbjct: 395 CIKEMEEESSIIFDFGGFYLSNWLSDFQLVTDSRSNICILGIAPQS-----DPTIILGDN 449
Query: 388 FLRKYYSIYDIGHDAVGLAKA 408
FL Y +YD+ + + +A+A
Sbjct: 450 FLANTYVVYDLDNMEISMAQA 470
>YIL015w [O] KOG1339 Aspartyl protease
Length = 587
Score = 85.9 bits (211), Expect = 1e-16
Identities = 88/367 (23%), Positives = 155/367 (41%), Gaps = 70/367 (19%)
Query: 96 YFTEITLGSPPQSFKVILDTGSSNLWV----------------------------PSAEC 127
Y T + +G+P QS V+ DTGS++ WV PS +C
Sbjct: 45 YATTLDIGTPSQSLTVLFDTGSADFWVMDSSNPFCLPNSNTSSYSNATYNGEEVKPSIDC 104
Query: 128 GSLACFLHTKYDHEASSTYK-ANGSEFAIQYGSGSL-EGYVSRDLLTIGDLVIPDQDFAE 185
S+ + Y+ SSTY+ F I Y G+ +G + ++I + IP+ F
Sbjct: 105 RSM-----STYNEHRSSTYQYLENGRFYITYADGTFADGSWGTETVSINGIDIPNIQFGV 159
Query: 186 ATSEPGLAFAFGKFDGILGLAY---DSI-----SVNRIVPPVYNAIKN-KLLDDPVFAFY 236
A +A G+LG+ + +S+ + N P +K+ K++D ++ +
Sbjct: 160 A------KYATTPVSGVLGIGFPRRESVKGYEGAPNEYYPNFPQILKSEKIIDVVAYSLF 213
Query: 237 LGDSDKSEDGGEASFGGIDEEKYTGEITWLP--------VRRKAYWEVKFEGIG------ 282
L D G FG IDE K++G++ P V A + +G+G
Sbjct: 214 LNSPDSGT--GSIVFGAIDESKFSGDLFTFPMVNEYPTIVDAPATLAMTIQGLGAQNKSS 271
Query: 283 LGEEYATLEGHGAAIDTGTSLIALPSGLAEILNAEIGAK-KGWSGQYSVDCESRDSLPDL 341
E T + +D+GTSL+ P +A+ + + + A G Y +DC S+ D+
Sbjct: 272 CEHETFTTTKYPVLLDSGTSLLNAPKVIADKMASFVNASYSEEEGIYILDCPV--SVGDV 329
Query: 342 TLNFNGYNFTITAYDYTLEVSGSCISAFTPMDFPEPVGPLAIIGDAFLRKYYSIYDIGHD 401
NF+ + I+ +L +S ++ +P ++GD FL Y ++D+ +
Sbjct: 330 EYNFDFGDLQISVPLSSLILSPETEGSYCGFAV-QPTNDSMVLGDVFLSSAYVVFDLDNY 388
Query: 402 AVGLAKA 408
+ LA+A
Sbjct: 389 KISLAQA 395
>SPAC26A3.01 [O] KOG1339 Aspartyl protease
Length = 514
Score = 81.3 bits (199), Expect = 2e-15
Identities = 88/366 (24%), Positives = 139/366 (37%), Gaps = 62/366 (16%)
Query: 96 YFTEITLGSPPQSFKVILDTGSSNLWVPSAECGSL------------------------A 131
YF +TLGS + + + LDTGS WV + +L A
Sbjct: 76 YFANLTLGSNERVYSLTLDTGSPYTWVTAKNITALSASEIWSDTDGVDAGRSTSDIRTNA 135
Query: 132 CFLHTKYDHEASSTYKANGSE--FAIQYGSG-SLEGYVSRDLLTIGDLVIPDQDFAEATS 188
C +T +D+ +++ + N S F YG ++ GY D L +P +F AT
Sbjct: 136 CTNYTCFDYSSTTARRTNSSTIGFLASYGDNTTVLGYNMVDNAYFAGLTLPGFEFGLATR 195
Query: 189 E---------PGLAFAFGKFDGILGLAYDSISVNRIVPP--VYNAIKNKLLDDPVFAFYL 237
E PG+ I G++ D V PP V + ++D P F YL
Sbjct: 196 EYDSSQISVTPGI-IGLSVAMTITGISSDD-KVVAFTPPTIVDQLVSANVIDTPAFGIYL 253
Query: 238 GDSDKSEDGGEASFGGIDEEKYTGEITWLPVRR---KAYWEVKFEGIGLGEEYATLEGHG 294
+ED GE FGG D+ K G + W+ + ++ V E I + ++
Sbjct: 254 -----NEDVGELIFGGYDKAKINGSVHWVNISSSDDSTFYSVNLESITVTNSTSSNNVQS 308
Query: 295 A-------------AIDTGTSLIALPSGLAEILNAEIGAKKGWSGQYSVDCESRDSLPDL 341
+ +DTGT I LP E + + G + C+S +
Sbjct: 309 SKRSSKDIEVNTTVTLDTGTVYIYLPEDTVESIADQYQGIVSEYGYVVIYCDSFSDSDYI 368
Query: 342 TLNF-NGYNFTITAYDYTLEVSGSCISAFTPMDFPEPVGPLAIIGDAFLRKYYSIYDIGH 400
+ NF + +F ++ D + S + E ++G FL+ YSIYD
Sbjct: 369 SFNFGSDADFHVSVNDLVIYRQESTSGDICYLALFEGDTSSYLLGQYFLQYVYSIYDWDA 428
Query: 401 DAVGLA 406
+GLA
Sbjct: 429 QKIGLA 434
>Hs21040364 [O] KOG1339 Aspartyl protease
Length = 457
Score = 77.8 bits (190), Expect = 3e-14
Identities = 85/339 (25%), Positives = 132/339 (38%), Gaps = 63/339 (18%)
Query: 96 YFTEITLGSPPQSFKVILDTGSSNLWVPSAECGSLACFLHTKYDHEASSTYKANGSEFAI 155
Y+ E+T+GSPPQ+ +++DTGSSN V +A FLH Y + SSTY+ +
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAP----HPFLHRYYQRQLSSTYRDLRKGVYV 130
Query: 156 QYGSGSLEGYVSRDLLTIGDLVIPDQDFAEATSEPGLAFAFGKFDGILGLAYDSISVNRI 215
Y G EG + DL PD EP +DS+
Sbjct: 131 PYTQGKWEGELGTDL--------PDDSL-----EP---------------FFDSLVKQTH 162
Query: 216 VPPVYNAIKNKLLDDPVFAFYLGDSD-KSEDGGEASFGGIDEEKYTGEITWLPVRRKAYW 274
VP +++ L F L S+ + GG GGID YTG + + P+RR+ Y+
Sbjct: 163 VPNLFS------LQLCGAGFPLNQSEVLASVGGSMIIGGIDHSLYTGSLWYTPIRREWYY 216
Query: 275 E-----VKFEGIGLGEEYATLEGHGAAIDTGTSLIALPSGLAEILNAEIGAKKG------ 323
E V+ G L + + +D+GT+ + LP + E I A
Sbjct: 217 EVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEAAVKSIKAASSTEKFPD 276
Query: 324 --WSGQYSVDCESRDS----LPDLTLNFNG------YNFTITAYDYTLEVSGSCISAFTP 371
W G+ V ++ + P ++L G + TI Y V S
Sbjct: 277 GFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRITILPQQYLRPVEDVATSQDDC 336
Query: 372 MDFP-EPVGPLAIIGDAFLRKYYSIYDIGHDAVGLAKAA 409
F ++G + +Y ++D +G A +A
Sbjct: 337 YKFAISQSSTGTVMGAVIMEGFYVVFDRARKRIGFAVSA 375
>CE04749 [O] KOG1339 Aspartyl protease
Length = 410
Score = 75.9 bits (185), Expect = 1e-13
Identities = 63/283 (22%), Positives = 124/283 (43%), Gaps = 14/283 (4%)
Query: 96 YFTEITLGSPPQSFKVILDTGSSNLWVPSAECGSLA-CFLHTKYDHEASSTYKANGSEFA 154
+ +T+G+P Q F V++DT ++++ +P C + C+ +++ SS+Y A G+++
Sbjct: 88 FVANLTMGTPGQLFTVVIDTSTADIVIPDMSCKTANNCYNKRRFNQAKSSSYYAYGNKYT 147
Query: 155 IQYGSGSLEGYVSRDLLTIGD-----LVIPDQDFAEATSEPGLAFAFGKFDGILGLAYDS 209
+ G+ +G+ ++D + IGD + IP F +AT L G DGILGL + +
Sbjct: 148 YKNNLGTFQGFDAKDTVVIGDRKTDLITIPGVKFMQATDLGLLMDGLGA-DGILGLGFTA 206
Query: 210 ISVNRIVPPVYNAIKNKLLDDPVFAFYLGDSDKSED---GGEASFGGIDEEKYTGEITWL 266
S P + + ++ +L ++++D G +GG D T++
Sbjct: 207 SSQIGGNSPFVQGVNAGDISGTFYSIWLEHFNQTDDLGTHGVIYYGGFDPVHCAPNPTYV 266
Query: 267 PVRRKAYWEV---KFEGIGLGEEYATLEGHGAAIDTGTSLIALPSGLAEILNAEIGAKKG 323
P+ +++ F+ +G + + +DT T+ I LP + +G
Sbjct: 267 PLASAYAYQLTMSSFKVVGSSATNSNNKYIQTYLDTTTAQIGLPKTYISQVFDSLGISTN 326
Query: 324 WSGQYSVDCESRDSLPDLTLNF-NGYNFTITAYDYTLEVSGSC 365
++ LT F +G +IT D + G+C
Sbjct: 327 VMNAIYPTIVPCNTKITLTFGFVSGTTVSITERDLVISFFGTC 369
>YIR039c [O] KOG1339 Aspartyl protease
Length = 537
Score = 73.2 bits (178), Expect = 7e-13
Identities = 83/380 (21%), Positives = 155/380 (39%), Gaps = 83/380 (21%)
Query: 96 YFTEITLGSPPQSFKVILDTGSSNLWVPSAE---CGSLA--------------------- 131
Y ++ +G+PPQ+ + LDTGSS++ V +A+ C S++
Sbjct: 67 YVVKMEIGTPPQTLYLQLDTGSSDMIVNNADIAYCKSMSDGSDYASTDNYELTATFNGLP 126
Query: 132 ------------CFLHTKYDHEASSTYKANGSEFAIQYGSGSL-EGYVSRDLLTIGDLVI 178
C +D SST++ N + F YG G+ G D+++ ++ +
Sbjct: 127 STTISSEAYNTLCSYWGTFDASNSSTFENNATFFNNTYGDGTYYAGTYGTDVVSFENITL 186
Query: 179 PDQDFAEATSEPGLAFAFGKFDGILGLAYD----------SISVNRIVPPVYNAIKNKL- 227
D F + G GILG++ ++++NR P +Y+ +L
Sbjct: 187 NDFTFGVSND------TIGNPSGILGISLPIAEFTDGIEYALALNR-TPFIYDNFPMELK 239
Query: 228 ----LDDPVFAFYLGDSDKSEDGGEASFGGIDEEKYTGEITWLPVRRKAYWEVKFEG-IG 282
++ ++ +L D G FG +D+ KYTG++ LP+ + G I
Sbjct: 240 NQGKINKIAYSLFLNGPDAHF--GSILFGAVDKSKYTGQLYTLPMLQAFNTLGSNPGMII 297
Query: 283 LGEEYATLEGHG-----------AAIDTGTSLIALPSGLAEILNAEIGAKKGWSGQ-YSV 330
+ A L+ +D+GT+ LP+ +AE + + Q Y
Sbjct: 298 TAQSVAILDSESGNKTVSDIQFPVMLDSGTTFSYLPTEIAEAIGKSFDGEYSSDDQGYIF 357
Query: 331 DCES-RDSLPDLTLNFNGYNFTITAYDYTLEVSGSCISAFTPMDFPEPVGPLAIIGDAFL 389
DC D+L L+++F G+N + ++ C+ + ++GDAFL
Sbjct: 358 DCSKVNDTL--LSVDFGGFNISANISNFVTSAKDRCVLNVKQSE------STYMLGDAFL 409
Query: 390 RKYYSIYDIGHDAVGLAKAA 409
Y +YD+ + + +A+A+
Sbjct: 410 VDAYVVYDLENYEISIAQAS 429
>CE09538 [O] KOG1339 Aspartyl protease
Length = 234
Score = 71.6 bits (174), Expect = 2e-12
Identities = 63/231 (27%), Positives = 105/231 (45%), Gaps = 43/231 (18%)
Query: 200 DGILGLAYDSISVNRI-VPPVYNAIKNKLLDDPVFAFYLGDSDKSED--GGEASFGGIDE 256
DG+LGLA S++ +R+ + P+ NAI+ LLDDP+F YL + + GG ++G +D
Sbjct: 22 DGVLGLA-PSMNYDRVFLSPLLNAIQQGLLDDPLFTVYLEKHGFTSNVPGGRFTYGAVDI 80
Query: 257 EKYTGEITWLPVRRKAYWEVKFEGIGLGEEYATLEGHGAAIDTGTSLIALPSGLAEILNA 316
+ G I +G+ +G Y DTGTS IA P + +
Sbjct: 81 DN-CGPI---------------DGVSIG-NYTLTRKMQVMTDTGTSFIAAPFYVLNEIIV 123
Query: 317 EIGAK-KGWSGQYSVDCESRDSLPDLTLNFNGYNFTITAYDYTLEVS------------- 362
+GA + Y V C S P+L + + + +Y ++VS
Sbjct: 124 TLGATYDNTTKSYYVSCNSEK--PNLNIVIGNNIYVVEPNNYVIDVSTEKIQRNITTAPI 181
Query: 363 -----GSCISAFTPMDFPEPVGPLAIIGDAFLRKYYSIYDIGHDAVGLAKA 408
C+ A + + +GP I+G F+R++ ++DIG+ +GLAK+
Sbjct: 182 TINQGDKCLLAISGLS-GYGMGPTWILGTLFMRQFCHVHDIGNQQIGLAKS 231
>At2g36670 [O] KOG1339 Aspartyl protease
Length = 469
Score = 68.2 bits (165), Expect = 2e-11
Identities = 89/374 (23%), Positives = 146/374 (38%), Gaps = 73/374 (19%)
Query: 91 YLNAQYFTEITLGSPPQSFKVILDTGSSNLWVPSAEC-------------------GSLA 131
YL YFT++ LGSPP F V +DTGS LWV + C GSL
Sbjct: 95 YLVGLYFTKVKLGSPPTEFNVQIDTGSDILWVTCSSCSNCPHSSGLGIDLHFFDAPGSLT 154
Query: 132 CFLHTKYDHEASSTYKANGSE--------FAIQYGSGS-LEGYVSRDLL----TIGDLVI 178
T D SS ++ ++ ++ +YG GS GY D +G+ ++
Sbjct: 155 AGSVTCSDPICSSVFQTTAAQCSENNQCGYSFRYGDGSGTSGYYMTDTFYFDAILGESLV 214
Query: 179 PDQD----FAEATSEPG-LAFAFGKFDGILGLAYDSISVNRIVPPVYNAIKNKLLDDPVF 233
+ F +T + G L + DGI G +S V + + ++ + PVF
Sbjct: 215 ANSSAPIVFGCSTYQSGDLTKSDKAVDGIFGFGKGKLS-------VVSQLSSRGITPPVF 267
Query: 234 AFYLGDSDKSEDGGEASFGGI---DEEKYTGEITWLPVRRKAYWEVKFEGIGLGEEYATL 290
+ L G+ S GG+ E G + V + ++ + IG+ + L
Sbjct: 268 SHCL--------KGDGSGGGVFVLGEILVPGMVYSPLVPSQPHYNLNLLSIGVNGQMLPL 319
Query: 291 EG--------HGAAIDTGTSLIALPSGLAEI-LNA------EIGAKKGWSGQ--YSVDCE 333
+ G +DTGT+L L ++ LNA ++ +G+ Y V
Sbjct: 320 DAAVFEASNTRGTIVDTGTTLTYLVKEAYDLFLNAISNSVSQLVTPIISNGEQCYLVSTS 379
Query: 334 SRDSLPDLTLNF-NGYNFTITAYDYTLEVSGSCISAFTPMDFPEPVGPLAIIGDAFLRKY 392
D P ++LNF G + + DY ++ + F + I+GD L+
Sbjct: 380 ISDMFPSVSLNFAGGASMMLRPQDYLFHYGIYDGASMWCIGFQKAPEEQTILGDLVLKDK 439
Query: 393 YSIYDIGHDAVGLA 406
+YD+ +G A
Sbjct: 440 VFVYDLARQRIGWA 453
>At3g50050 [O] KOG1339 Aspartyl protease
Length = 632
Score = 66.6 bits (161), Expect = 6e-11
Identities = 75/300 (25%), Positives = 121/300 (40%), Gaps = 56/300 (18%)
Query: 92 LNAQYFTEITLGSPPQSFKVILDTGSSNLWVPSAECGSLACFLHTKYDHEASSTYK---- 147
+N Y T + +G+PPQ F +I+D+GS+ +VP ++C K+ E SSTY+
Sbjct: 89 INGYYTTRLWIGTPPQMFALIVDSGSTVTYVPCSDCEQCGKHQDPKFQPEMSSTYQPVKC 148
Query: 148 ---------ANGSEFAIQYGS-GSLEGYVSRDLLTIGD---LVIPDQDFAEATSEPGLAF 194
+ +Y S +G + DL++ G+ L F T E G +
Sbjct: 149 NMDCNCDDDREQCVYEREYAEHSSSKGVLGEDLISFGNESQLTPQRAVFGCETVETGDLY 208
Query: 195 AFGKFDGILGLAYDSISVNRIVPPVYNAIKNKLLDDPVFAFYLGDSDKSEDGGEASFGGI 254
+ + DGI+GL +S + + + +K L F G D GG GG
Sbjct: 209 S-QRADGIIGLGQGDLS-------LVDQLVDKGLISNSFGLCYGGMDVG--GGSMILGGF 258
Query: 255 DEEKYTGEITWL--PVRRKAYWEVKFEGIGLGEEYATLEG------HGAAIDTGTSLIAL 306
D Y ++ + R Y+ + GI + + +L HGA +D+GT+ L
Sbjct: 259 D---YPSDMVFTDSDPDRSPYYNIDLTGIRVAGKQLSLHSRVFDGEHGAVLDSGTTYAYL 315
Query: 307 P----SGLAEILNAEIGAKKGWSGQYSVDCESRDSLPDLTLNFNGYNFTITAYDYTLEVS 362
P + E + E+ K G PD NF F + A +Y E+S
Sbjct: 316 PDAAFAAFEEAVMREVSTLKQIDG------------PD--PNFKDTCFQVAASNYVSELS 361
>At3g02740 [O] KOG1339 Aspartyl protease
Length = 488
Score = 62.0 bits (149), Expect = 2e-09
Identities = 91/365 (24%), Positives = 140/365 (37%), Gaps = 72/365 (19%)
Query: 96 YFTEITLGSPPQSFKVILDTGSSNLWVPSAECGSLAC------FLHTKYDHEASSTYKA- 148
YF +I LG+P + F V +DTGS LWV A C + C T YD +ASST K+
Sbjct: 85 YFAKIGLGTPSRDFHVQVDTGSDILWVNCAGC--IRCPRKSDLVELTPYDVDASSTAKSV 142
Query: 149 -----------------NGS--EFAIQYGSG-SLEGYVSRDLLTIGDLVIPDQD------ 182
+GS ++ I YG G S GY+ +D++ + DLV ++
Sbjct: 143 SCSDNFCSYVNQRSECHSGSTCQYVIMYGDGSSTNGYLVKDVVHL-DLVTGNRQTGSTNG 201
Query: 183 ---FAEATSEPG-LAFAFGKFDGILGLAYDSISVNRIVPPVYNAIKNKLLDDPVFAFYLG 238
F + + G L + DGI+G + S I V +
Sbjct: 202 TIIFGCGSKQSGQLGESQAAVDGIMGFGQSNSSF----------ISQLASQGKVKRSFAH 251
Query: 239 DSDKSEDGGEASFGGIDEEKYTGEITWLPVRRKAYWEVKFEGIGLGEEYATLEGH----- 293
D + GG + G + K T + + A++ V I +G L +
Sbjct: 252 CLDNNNGGGIFAIGEVVSPKVK---TTPMLSKSAHYSVNLNAIEVGNSVLELSSNAFDSG 308
Query: 294 ---GAAIDTGTSLIALPSGLAEILNAEIGAKKG----WSGQYSVDC----ESRDSLPDLT 342
G ID+GT+L+ LP + L EI A + Q S C + D P +T
Sbjct: 309 DDKGVIIDSGTTLVYLPDAVYNPLLNEILASHPELTLHTVQESFTCFHYTDKLDRFPTVT 368
Query: 343 LNFN-GYNFTITAYDYTLEVSGS--CISAFTPMDFPEPVGPLAIIGDAFLRKYYSIYDIG 399
F+ + + +Y +V C + L I+GD L +YDI
Sbjct: 369 FQFDKSVSLAVYPREYLFQVREDTWCFGWQNGGLQTKGGASLTILGDMALSNKLVVYDIE 428
Query: 400 HDAVG 404
+ +G
Sbjct: 429 NQVIG 433
>SPCC1795.09 [O] KOG1339 Aspartyl protease
Length = 521
Score = 60.5 bits (145), Expect = 4e-09
Identities = 90/398 (22%), Positives = 148/398 (36%), Gaps = 60/398 (15%)
Query: 57 LNSFQRAYPQESFSKDNVDVFVAPEGSHSVPLTNYLNAQYFTEITLGSPPQSFKVILDTG 116
L+ + +P + + D +P G S PL Y T +++G P S+ V +D
Sbjct: 28 LDFVAKTFPNQENQLEKRDYTYSPSGITSFPLDLQSYTYYTTTLSIGRPSISYTVAIDLD 87
Query: 117 SSNLWV-------------------PSAECGSLACFLHTK-----YDHEASSTYK--ANG 150
W+ L FL K Y ASS++ +
Sbjct: 88 MPYTWLTYYNVMAFNPAYLGIVNSGTQWSTDELRYFLCKKESDSCYFGNASSSFHFVTSP 147
Query: 151 SEFAIQYGSG-SLEGYVSRDLLTIGDL-VIPDQDFAEATSEPGLAFAFGKFDGILGLAYD 208
S F I+Y ++ G +D L+ +PD F T + + + + G+LGLA
Sbjct: 148 STFFIRYDDNITVAGINVQDSLSYSHYQALPDFQFG-ITLKEYVPSSMLPYKGVLGLAAS 206
Query: 209 --------SISVNRIVPPVY--NAIKNKLLDDPVFAFYLGDSDKSEDGGEASFGGIDEEK 258
S S++ PP + +K +L P F+ YL ++ G G +D K
Sbjct: 207 TEINSIDYSDSISSFSPPTFLEQLVKEDILAYPAFSMYL----DNQGNGSLLLGAVDTSK 262
Query: 259 YTGEITWLPVRRKAY-----WEVKFEGIGLGEEYATLEGHGAAIDTGTSLIALPSGLAEI 313
Y G+ L + + + V+F Y+ + A T + I LP+ LA
Sbjct: 263 YQGQFVALKQTKLTHYAVSIYSVQFLNSTFFSNYSIIT--DAYFQTRETYIYLPAELAYS 320
Query: 314 LNAEIGAKKGWSGQYSVDCESRDSLPDLTLNFNGYNFTITAYDYTL---EVSGSCISAFT 370
+ GA G ++++C+ D L F G N TI L +VS C+
Sbjct: 321 VMDNAGAYLS-EGYFALNCDEIDLEAALIFQF-GCNSTIKVPISLLVIGQVSNICLLGIR 378
Query: 371 PMDFPEPVGPLAIIGDAFLRKYYSIYDIGHDAVGLAKA 408
P E ++G F R Y+ Y + + +A
Sbjct: 379 PSTDSE-----IVLGLLFFRNAYTFYHQSQKMIAIGQA 411
>At1g65240 [O] KOG1339 Aspartyl protease
Length = 475
Score = 60.5 bits (145), Expect = 4e-09
Identities = 87/362 (24%), Positives = 141/362 (38%), Gaps = 64/362 (17%)
Query: 96 YFTEITLGSPPQSFKVILDTGSSNLWVPSAECGSLAC-----FLHTKYDHEASSTYK--- 147
YFT+I LGSPP+ + V +DTGS LW+ C F + +D ASST K
Sbjct: 74 YFTKIKLGSPPKEYHVQVDTGSDILWINCKPCPKCPTKTNLNFRLSLFDMNASSTSKKVG 133
Query: 148 -----------------ANGSEFAIQYGSGSL-EGYVSRDLLTI----GDL----VIPDQ 181
A G + I Y S +G RD+LT+ GDL + +
Sbjct: 134 CDDDFCSFISQSDSCQPALGCSYHIVYADESTSDGKFIRDMLTLEQVTGDLKTGPLGQEV 193
Query: 182 DFAEATSEPG-LAFAFGKFDGILGLAYDSISVNRIVPPVYNAIKNKLLDDPVFAFYLGDS 240
F + + G L DG++G + SV + +A + VF+ L
Sbjct: 194 VFGCGSDQSGQLGNGDSAVDGVMGFGQSNTSVLSQLAATGDAKR-------VFSHCL--- 243
Query: 241 DKSEDGGEASFGGIDEEKYTGEITWLPVRRKAYWEVKF-----EGIGLGEEYATLEGHGA 295
D + GG + G +D K T V + ++ V +G L + + G
Sbjct: 244 DNVKGGGIFAVGVVDSPKVK---TTPMVPNQMHYNVMLMGMDVDGTSLDLPRSIVRNGGT 300
Query: 296 AIDTGTSLIALPSGLAEILNAEIGAKKGWSGQ--------YSVDCESRDSLPDLTLNF-N 346
+D+GT+L P L + L I A++ +S ++ P ++ F +
Sbjct: 301 IVDSGTTLAYFPKVLYDSLIETILARQPVKLHIVEETFQCFSFSTNVDEAFPPVSFEFED 360
Query: 347 GYNFTITAYDY--TLEVSGSCISAFTPMDFPEPVGPLAIIGDAFLRKYYSIYDIGHDAVG 404
T+ +DY TLE C + + ++GD L +YD+ ++ +G
Sbjct: 361 SVKLTVYPHDYLFTLEEELYCFGWQAGGLTTDERSEVILLGDLVLSNKLVVYDLDNEVIG 420
Query: 405 LA 406
A
Sbjct: 421 WA 422
>At5g10760 [O] KOG1339 Aspartyl protease
Length = 464
Score = 59.7 bits (143), Expect = 8e-09
Identities = 83/353 (23%), Positives = 137/353 (38%), Gaps = 60/353 (16%)
Query: 93 NAQYFTEITLGSPPQSFKVILDTGSSNLWVPSAEC-GSLACFLHTKYDHEASSTYK---- 147
+ Y I +G+P ++ DTGS W C GS K++ +SSTY+
Sbjct: 129 SGNYIVTIGIGTPKHDLSLVFDTGSDLTWTQCEPCLGSCYSQKEPKFNPSSSSTYQNVSC 188
Query: 148 ------------ANGSEFAIQYGSGSL-EGYVSRDLLTIGDL-VIPDQDFAEATSEPGLA 193
A+ ++I YG S +G+++++ T+ + V+ D F + GL
Sbjct: 189 SSPMCEDAESCSASNCVYSIVYGDKSFTQGFLAKEKFTLTNSDVLEDVYFGCGENNQGL- 247
Query: 194 FAFGKFDGILGLAYDSISVNRIVPPVYNAIKNKLLDDPVFAFYLGDSDKSEDGGEASFG- 252
F G+LGL +S+ YN I F++ L S S G +FG
Sbjct: 248 --FDGVAGLLGLGPGKLSLPAQTTTTYNNI---------FSYCL-PSFTSNSTGHLTFGS 295
Query: 253 -GIDEEKYTGEITWLPVRRKAYWEVKFEGIGLGEEYATL-----EGHGAAIDTGTSLIAL 306
GI E I+ P + + GI +G++ + GA ID+GT L
Sbjct: 296 AGISESVKFTPISSFP--SAFNYGIDIIGISVGDKELAITPNSFSTEGAIIDSGTVFTRL 353
Query: 307 P----SGLAEILNAEIGAKKGWSG----QYSVDCESRDSLPDLTLNFNGYNFTITAYD-- 356
P + L + ++ + K SG D D++ T+ F+ T+ D
Sbjct: 354 PTKVYAELRSVFKEKMSSYKSTSGYGLFDTCYDFTGLDTVTYPTIAFSFAGSTVVELDGS 413
Query: 357 ---YTLEVSGSCISAFTPMDFPEPVGPLAIIGDAFLRKYYSIYDIGHDAVGLA 406
+++S C++ D P AI G+ +YD+ VG A
Sbjct: 414 GISLPIKISQVCLAFAGNDDLP------AIFGNVQQTTLDVVYDVAGGRVGFA 460
>Hs21040368 [O] KOG1339 Aspartyl protease
Length = 432
Score = 58.2 bits (139), Expect = 2e-08
Identities = 31/76 (40%), Positives = 43/76 (55%), Gaps = 4/76 (5%)
Query: 96 YFTEITLGSPPQSFKVILDTGSSNLWVPSAECGSLACFLHTKYDHEASSTYKANGSEFAI 155
Y+ E+T+GSPPQ+ +++DTGSSN V +A FLH Y + SSTY+ +
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAP----HPFLHRYYQRQLSSTYRDLRKGVYV 130
Query: 156 QYGSGSLEGYVSRDLL 171
Y G EG + DLL
Sbjct: 131 PYTQGKWEGELGTDLL 146
>At3g54400 [O] KOG1339 Aspartyl protease
Length = 425
Score = 57.8 bits (138), Expect = 3e-08
Identities = 74/352 (21%), Positives = 130/352 (36%), Gaps = 58/352 (16%)
Query: 96 YFTEITLGSPPQSFKVILDTGSSNLWVPSAECGSLACFLHTKYDHEASSTYKANGSE--- 152
Y +G+P Q V LDT + W+P + C + C +D SS+ + E
Sbjct: 88 YIVRANIGTPAQPMLVALDTSNDAAWIPCSGC--VGCSSSVLFDPSKSSSSRTLQCEAPQ 145
Query: 153 ----------------FAIQYGSGSLEGYVSRDLLTIGDLVIPDQDFAEATSEPGLAFAF 196
F + YG ++E Y+++D LT+ VIP+ F G +
Sbjct: 146 CKQAPNPSCTVSKSCGFNMTYGGSTIEAYLTQDTLTLASDVIPNYTFGCINKASGTSL-- 203
Query: 197 GKFDGILGLAYDSISVNRIVPPVYNAIKNKLLDDPVFAFYLGDSDKSEDGGEASFGGIDE 256
G++GL +S+ +++ L F++ L +S S G G ++
Sbjct: 204 -PAQGLMGLGRGPLSL---------ISQSQNLYQSTFSYCLPNSKSSNFSGSLRLGPKNQ 253
Query: 257 EKYTGEITWLP-VRRKAYWEVKFEGIGLGEEYATL----------EGHGAAIDTGTSLIA 305
L RR + + V GI +G + + G G D+GT
Sbjct: 254 PIRIKTTPLLKNPRRSSLYYVNLVGIRVGNKIVDIPTSALAFDPATGAGTIFDSGTVYTR 313
Query: 306 L--PSGLA-------EILNAEIGAKKGWSGQYSVDCESRDSLPDLTLNFNGYNFTITAYD 356
L P+ +A + NA + G+ YS P +T F G N T+ +
Sbjct: 314 LVEPAYVAVRNEFRRRVKNANATSLGGFDTCYS----GSVVFPSVTFMFAGMNVTLPPDN 369
Query: 357 YTLEVSGSCISAFTPMDFPEPVGP-LAIIGDAFLRKYYSIYDIGHDAVGLAK 407
+ S +S P V L +I + + + D+ + +G+++
Sbjct: 370 LLIHSSAGNLSCLAMAAAPVNVNSVLNVIASMQQQNHRVLIDVPNSRLGISR 421
>At5g43100 [O] KOG1339 Aspartyl protease
Length = 586
Score = 56.2 bits (134), Expect = 8e-08
Identities = 82/359 (22%), Positives = 139/359 (37%), Gaps = 61/359 (16%)
Query: 93 NAQYFTEITLGSPPQSFKVILDTGSSNLWVPSAECGSLACFLHTKYDHEASSTYKANGSE 152
N Y T + +G+PPQ F +I+DTGS+ +VP + C K+ E S++Y+A
Sbjct: 73 NGYYTTRLWIGTPPQEFALIVDTGSTVTYVPCSTCKQCGKHQDPKFQPELSTSYQALKCN 132
Query: 153 -------------FAIQYGS-GSLEGYVSRDLLTIGD---LVIPDQDFAEATSEPGLAFA 195
+ +Y S G +S DL++ G+ L F E G F+
Sbjct: 133 PDCNCDDEGKLCVYERRYAEMSSSSGVLSEDLISFGNESQLSPQRAVFGCENEETGDLFS 192
Query: 196 FGKFDGILGLAYDSISVNRIVPPVYNAIKNKLLDDPVFAFYLGDSDKSEDGGEASFGGID 255
+ DGI+GL +S V + + +K + + VF+ G E GG A G
Sbjct: 193 -QRADGIMGLGRGKLS-------VVDQLVDKGVIEDVFSLCYGG---MEVGGGAMVLGKI 241
Query: 256 EEKYTGEITWLPVRRKAYWEVKFEGIGLGEEYATLE------GHGAAIDTGTSLIALPS- 308
+ R Y+ + + + + + L HG +D+GT+ P
Sbjct: 242 SPPPGMVFSHSDPFRSPYYNIDLKQMHVAGKSLKLNPKVFNGKHGTVLDSGTTYAYFPKE 301
Query: 309 ---GLAEILNAEIGAKK---GWSGQYSVDC---------ESRDSLPDLTLNF-NGYNFTI 352
+ + + EI + K G Y C E + P++ + F NG +
Sbjct: 302 AFIAIKDAVIKEIPSLKRIHGPDPNYDDVCFSGAGRDVAEIHNFFPEIAMEFGNGQKLIL 361
Query: 353 TAYDYTL---EVSGS-CISAFTPMDFPEPVGPLAIIGDAFLRKYYSIYDIGHDAVGLAK 407
+ +Y +V G+ C+ F D ++G +R YD +D +G K
Sbjct: 362 SPENYLFRHTKVRGAYCLGIFPDRD------STTLLGGIVVRNTLVTYDRENDKLGFLK 414
>At5g07030 [O] KOG1339 Aspartyl protease
Length = 439
Score = 52.8 bits (125), Expect = 9e-07
Identities = 73/363 (20%), Positives = 130/363 (35%), Gaps = 77/363 (21%)
Query: 96 YFTEITLGSPPQSFKVILDTGSSNLWVPSAECGSLACFLHTKYDHEASSTYK-------- 147
Y + +G+P Q + +DT S W+P + C + C +T + S+++K
Sbjct: 99 YIVKALIGTPAQPLLLAMDTSSDVAWIPCSGC--VGCPSNTAFSPAKSTSFKNVSCSAPQ 156
Query: 148 ----------ANGSEFAIQYGSGSLEGYVSRDLLTIGDLVIPDQDFAEATSEPGLAFAFG 197
A F + YGS S+ +S+D + + ++P AF FG
Sbjct: 157 CKQVPNPTCGARACSFNLTYGSSSIAANLSQDTIRL-------------AADPIKAFTFG 203
Query: 198 KFD------------GILGLAYDSISVNRIVPPVYNAIKNKLLDDPVFAFYLGDSDKSED 245
+ G+LGL +S+ +Y + F++ L
Sbjct: 204 CVNKVAGGGTIPPPQGLLGLGRGPLSLMSQAQSIYKS---------TFSYCLPSFRSLTF 254
Query: 246 GGEASFGGIDEE---KYTGEITWLPVRRKAYWEVKFEGIGLGEEYATL----------EG 292
G G + KYT ++ P RR + + V I +G + L G
Sbjct: 255 SGSLRLGPTSQPQRVKYT-QLLRNP-RRSSLYYVNLVAIRVGRKVVDLPPAAIAFNPSTG 312
Query: 293 HGAAIDTGTSLIALPSGLAEILNAEIGAKKGWS-------GQYSVDCESRDSLPDLTLNF 345
G D+GT L + E + E + + G + + +P +T F
Sbjct: 313 AGTIFDSGTVYTRLAKPVYEAVRNEFRKRVKPTTAVVTSLGGFDTCYSGQVKVPTITFMF 372
Query: 346 NGYNFTITAYDYTLEVSGSCISAFTPMDFPEPVGPLA-IIGDAFLRKYYSIYDIGHDAVG 404
G N T+ A + L + S PE V + +I + + + D+ + +G
Sbjct: 373 KGVNMTMPADNLMLHSTAGSTSCLAMAAAPENVNSVVNVIASMQQQNHRVLIDVPNGRLG 432
Query: 405 LAK 407
LA+
Sbjct: 433 LAR 435
>At3g18490 [O] KOG1339 Aspartyl protease
Length = 500
Score = 52.8 bits (125), Expect = 9e-07
Identities = 81/364 (22%), Positives = 133/364 (36%), Gaps = 76/364 (20%)
Query: 93 NAQYFTEITLGSPPQSFKVILDTGSSNLWVPSAECGSLACFLHTKYDHEASSTYK----- 147
+ +YF+ I +G+P + ++LDTGS W+ C ++ +SSTYK
Sbjct: 159 SGEYFSRIGVGTPAKEMYLVLDTGSDVNWIQCEPCADCYQQSDPVFNPTSSSTYKSLTCS 218
Query: 148 -------------ANGSEFAIQYGSGSLEGYVSRDLLTIGDLVIPDQDFAEATSEPGLAF 194
+N + + YG GS T+G+L F + +A
Sbjct: 219 APQCSLLETSACRSNKCLYQVSYGDGS---------FTVGELATDTVTFGNSGKINNVAL 269
Query: 195 AFG-KFDGILGLAYDSISVNRIVPPVYNAIKNKLLDDPVFAFYLGDSD----KSEDGGEA 249
G +G+ A + + V + N +K F++ L D D S D
Sbjct: 270 GCGHDNEGLFTGAAGLLGLGGGVLSITNQMK-----ATSFSYCLVDRDSGKSSSLDFNSV 324
Query: 250 SFGGIDEEKYTGEITWLPVRRK---AYWEVKFEGIGLGEEYATLE----------GHGAA 296
GG G+ T +R K ++ V G +G E L G
Sbjct: 325 QLGG-------GDATAPLLRNKKIDTFYYVGLSGFSVGGEKVVLPDAIFDVDASGSGGVI 377
Query: 297 IDTGTSLIALPSGLAE-----ILNAEIGAKKGWSG------QYSVDCESRDSLPDLTLNF 345
+D GT++ L + L + KKG S Y S +P + +F
Sbjct: 378 LDCGTAVTRLQTQAYNSLRDAFLKLTVNLKKGSSSISLFDTCYDFSSLSTVKVPTVAFHF 437
Query: 346 -NGYNFTITAYDYTLEV--SGSCISAFTPMDFPEPVGPLAIIGDAFLRKYYSIYDIGHDA 402
G + + A +Y + V SG+ AF P L+IIG+ + YD+ +
Sbjct: 438 TGGKSLDLPAKNYLIPVDDSGTFCFAFAPTS-----SSLSIIGNVQQQGTRITYDLSKNV 492
Query: 403 VGLA 406
+GL+
Sbjct: 493 IGLS 496
>At5g33340 [O] KOG1339 Aspartyl protease
Length = 437
Score = 52.0 bits (123), Expect = 2e-06
Identities = 72/315 (22%), Positives = 130/315 (40%), Gaps = 55/315 (17%)
Query: 93 NAQYFTEITLGSPPQSFKVILDTGSSNLWVPSAECGSLACFLHTKYDHEASSTYK----- 147
+ +Y +++G+PP I DTGS LW A C + +D + SSTYK
Sbjct: 87 SGEYLMNVSIGTPPFPIMAIADTGSDLLWTQCAPCDDCYTQVDPLFDPKTSSTYKDVSCS 146
Query: 148 ----------------ANGSEFAIQYGSGS-LEGYVSRDLLTIGDLVIPDQDFAEATSEP 190
N +++ YG S +G ++ D LT+G
Sbjct: 147 SSQCTALENQASCSTNDNTCSYSLSYGDNSYTKGNIAVDTLTLGSSDTRPMQLKNIIIGC 206
Query: 191 G--LAFAFG-KFDGILGLAYDSISVNRIVPPVYNAIKNKLLDDPVFAFYLGD-SDKSEDG 246
G A F K GI+GL +S ++ + ++I K F++ L + K +
Sbjct: 207 GHNNAGTFNKKGSGIVGLGGGPVS---LIKQLGDSIDGK------FSYCLVPLTSKKDQT 257
Query: 247 GEASFGGIDEEKYTGEITWLPVRRKA----YWEVKFEGIGLGEEYATLEGHGA------- 295
+ +FG +G ++ P+ KA ++ + + I +G + G +
Sbjct: 258 SKINFGTNAIVSGSGVVS-TPLIAKASQETFYYLTLKSISVGSKQIQYSGSDSESSEGNI 316
Query: 296 AIDTGTSLIALP----SGLAEILNAEIGAKKGWSGQYSVD-CESRD---SLPDLTLNFNG 347
ID+GT+L LP S L + + + I A+K Q + C S +P +T++F+G
Sbjct: 317 IIDSGTTLTLLPTEFYSELEDAVASSIDAEKKQDPQSGLSLCYSATGDLKVPVITMHFDG 376
Query: 348 YNFTITAYDYTLEVS 362
+ + + + ++VS
Sbjct: 377 ADVKLDSSNAFVQVS 391
>At1g08210 [O] KOG1339 Aspartyl protease
Length = 566
Score = 51.2 bits (121), Expect = 3e-06
Identities = 67/257 (26%), Positives = 98/257 (38%), Gaps = 69/257 (26%)
Query: 91 YLNAQYFTEITLGSPPQSFKVILDTGSSNLWVPSAECG-------------------SLA 131
+L Y+T++ LG+PP+ F V +DTGS LWV C S +
Sbjct: 127 FLVGLYYTKVKLGTPPREFNVQIDTGSDVLWVSCTSCNGCPKTSELQIQLSFFDPGVSSS 186
Query: 132 CFLHTKYDHEASSTYKA-------NGSEFAIQYGSGS-LEGYVSRDL----LTIGDLVIP 179
L + D S ++ N ++ +YG GS GY D L GDL P
Sbjct: 187 ASLVSCSDRRCYSNFQTESGCSPNNLCSYSFKYGDGSGTSGYYISDFMCSNLQSGDLQRP 246
Query: 180 DQDFAEATSEPGLAFAFGKFDGILGLAYDSISVNRIVPPVYNAIKNKLLDDPVFAFYLGD 239
+ DGI GL S+S V + + + L VF+ L
Sbjct: 247 RR----------------AVDGIFGLGQGSLS-------VISQLAVQGLAPRVFSHCL-K 282
Query: 240 SDKSEDGGEASFGGIDEEKYTGEITWLP-VRRKAYWEVKFEGIGLGEEYATLE------- 291
DKS GG G I + + P V + ++ V + I + + ++
Sbjct: 283 GDKS-GGGIMVLGQIKRP----DTVYTPLVPSQPHYNVNLQSIAVNGQILPIDPSVFTIA 337
Query: 292 -GHGAAIDTGTSLIALP 307
G G IDTGT+L LP
Sbjct: 338 TGDGTIIDTGTTLAYLP 354
>Hs18549644 [O] KOG1339 Aspartyl protease
Length = 110
Score = 50.1 bits (118), Expect = 6e-06
Identities = 27/83 (32%), Positives = 43/83 (51%), Gaps = 4/83 (4%)
Query: 326 GQYSVDCESRDSLPDLTLNFNGYNFTITAYDYTLEVSGSCISAFTPMDFPEPVGPLAIIG 385
GQ+ +DC S+P +G + + YT + G C S F D+ I+G
Sbjct: 31 GQFDIDCGRLSSIPTAVFEIHGKKYPLPPSAYTSQDQGFCTSGFQG-DYSSQQW---ILG 86
Query: 386 DAFLRKYYSIYDIGHDAVGLAKA 408
+ F+ +YYS++D ++ VGLAKA
Sbjct: 87 NVFIWEYYSVFDRTNNRVGLAKA 109
>At1g09750 [O] KOG1339 Aspartyl protease
Length = 387
Score = 50.1 bits (118), Expect = 6e-06
Identities = 70/294 (23%), Positives = 112/294 (37%), Gaps = 59/294 (20%)
Query: 85 SVPLT--NYLN-AQYFTEITLGSPPQSFKVILDTGSSNLWVPSAECGSLACFLHTKYDHE 141
SVP+ N L+ Y LG+PPQ ++LDT + +W+P + C + T ++
Sbjct: 90 SVPVASGNQLHIGNYVVRAKLGTPPQLMFMVLDTSNDAVWLPCSGCSGCS-NASTSFNTN 148
Query: 142 ASSTY-----------KANG------------SEFAIQY-GSGSLEGYVSRDLLTIGDLV 177
+SSTY +A G F Y G S + +D LT+ V
Sbjct: 149 SSSTYSTVSCSTAQCTQARGLTCPSSSPQPSVCSFNQSYGGDSSFSASLVQDTLTLAPDV 208
Query: 178 IPDQDFAEATSEPGLAFAFGKFDGILGLAYDSISVNRIVPPVYNAIKNKLLDDPVFAFYL 237
IP+ F S G + G++GL +S+ +Y+ VF++ L
Sbjct: 209 IPNFSFGCINSASGNSL---PPQGLMGLGRGPMSLVSQTTSLYSG---------VFSYCL 256
Query: 238 GDSDKSEDGGEASFGGIDEEKYTGEITWLPV----RRKAYWEVKFEGIGLGE-------E 286
G G + + K I + P+ RR + + V G+ +G
Sbjct: 257 PSFRSFYFSGSLKLGLLGQPK---SIRYTPLLRNPRRPSLYYVNLTGVSVGSVQVPVDPV 313
Query: 287 YATLE---GHGAAIDTGTSLIALPSGLAEILNAEIGAKKGWSGQYSVDCESRDS 337
Y T + G G ID+GT + + E + E +K G V RD+
Sbjct: 314 YLTFDANSGAGTIIDSGTVITRFAQPVYEAIRDEF--RKQQRGNADVSIHGRDT 365
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.316 0.137 0.407
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,711,343
Number of Sequences: 60738
Number of extensions: 1117747
Number of successful extensions: 2595
Number of sequences better than 1.0e-05: 74
Number of HSP's better than 0.0 without gapping: 38
Number of HSP's successfully gapped in prelim test: 36
Number of HSP's that attempted gapping in prelim test: 2295
Number of HSP's gapped (non-prelim): 93
length of query: 409
length of database: 30,389,216
effective HSP length: 109
effective length of query: 300
effective length of database: 23,768,774
effective search space: 7130632200
effective search space used: 7130632200
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)