ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIV1618 good E KOG2436 Amino acid transport and metabolism Acetylglutamate kinase/acetylglutamate synthase
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIV1618 559526 561181 552
(552 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YJL071w [E] KOG2436 Acetylglutamate kinase/acetylglutamate synthase 481 e-135
SPBC725.14 [E] KOG2436 Acetylglutamate kinase/acetylglutamate sy... 174 3e-43
Hs20559071 [E] KOG2436 Acetylglutamate kinase/acetylglutamate sy... 54 6e-07
>YJL071w [E] KOG2436 Acetylglutamate kinase/acetylglutamate synthase
Length = 574
Score = 481 bits (1237), Expect = e-135
Identities = 267/572 (46%), Positives = 367/572 (63%), Gaps = 32/572 (5%)
Query: 5 WIRCLTTEVRYHQPNAHGRSLVMSVLNSTVTKREAKDYLNKYT-DENNHHYCLVFLRHLS 63
W R E++Y QPNA ++L++SVLN+T TKREAKDYL+KYT D H++CL F+R L
Sbjct: 2 WRRIFAHELKYDQPNASSKNLILSVLNTTATKREAKDYLSKYTNDSGQHNHCLFFIRDLH 61
Query: 64 EYSDNVLSGFSKTVSRIQTLGLRPILIVDPLCQDISYQSQRLDNHLHDQSLKSIIVLDPI 123
+ + +LS FS + R+ LGLRP+ ++ P ++ Q++ LD+ + + LK + + + +
Sbjct: 62 KVAPAILSQFSSVIKRLGMLGLRPMFVIPPSPTHVNIQAELLDSIVTEADLKPLHLKEGL 121
Query: 124 TIGERGSIDVKLXXXXXXXXXXXXX-------YQYHEKEAFKKLAGDPSRFLSSLVSNLP 176
T G Y Y+E+ A + + D +F+ L
Sbjct: 122 TKSRTGLYHSVFSQESRFFDIGNSNFIPIVKPYVYNEETASEFMTKDVVKFMDCLCQGNI 181
Query: 177 INIDKVFLISKYGGLPSVERHTNSHVFVNLSQEYRELRNSYQNQLEKLESIQVDNTEKNL 236
+IDK F+++ GG+PS ER+ N+HVF+NLSQE L +S + + L + + +NL
Sbjct: 182 PHIDKFFILNNAGGIPSGERNDNAHVFINLSQELEHLSSSLSHNISTLT--KREPRSQNL 239
Query: 237 VESLQLFLNQDKILSNSDQLKCHMEDLEIMNKTLSVLPHSSTGLITTILAGSKLSDN-NP 295
+ +++++ +D+I S + H+E+L +M+K LS L ++TGLITT+ A + SD NP
Sbjct: 240 LHRMEVYVKKDEISSLECEYHDHLENLLLMDKVLSNLAATATGLITTVKAAALSSDRKNP 299
Query: 296 LVYNILTDRSLISSSLPRFKRSAAA--------QSKSWYELPSSNVEEEVTSANDSVLVT 347
LVYN+LTDRSLISSSLPRFK+ +WYELPS V S +D+VLVT
Sbjct: 300 LVYNLLTDRSLISSSLPRFKKKDGEIDSPANMFDDHAWYELPSQQVNA-APSNSDAVLVT 358
Query: 348 TVFKKGIDIHIFDFRTLTDDNSIGLP-----PSQATQTGKSDPVSKKLDLNKLNGIINSS 402
TV KKG+ I +D++TLT NSIGLP P + + + P KLD+NK II+ S
Sbjct: 359 TVLKKGVHIKTYDYKTLTQFNSIGLPKKFHVPEKGAKPSSNSP---KLDINKFKSIIDQS 415
Query: 403 FKRSLDLSHYLGRINGNIASIIVIGDYEGIAILTYEGPKDKQFVYLDKFAVAQKLKGSLG 462
FKRSLDL Y+ RING IA+IIVIGDYEGIAILTYEG ++ FVYLDKFAV LKGSLG
Sbjct: 416 FKRSLDLHDYIKRINGKIATIIVIGDYEGIAILTYEGSEENSFVYLDKFAVLPHLKGSLG 475
Query: 463 ISDIIFNLMFRKFPHELIWRSREDNVVNKWYFQRSTGVLHLSLDLGND--DQKQSIFKLF 520
ISDIIFNLMF+KFP+E++WRSR+DNVVNKWYFQRS VL LS+DL + D+KQS FKLF
Sbjct: 476 ISDIIFNLMFKKFPNEILWRSRKDNVVNKWYFQRSVAVLDLSIDLDPEHCDEKQSQFKLF 535
Query: 521 YYGNPE--SESFHNVERLRDYAKYVRDITPSW 550
YYGNP+ + + +RLR++ + VRDI PSW
Sbjct: 536 YYGNPQYAKRALRDKKRLREFMRSVRDIKPSW 567
>SPBC725.14 [E] KOG2436 Acetylglutamate kinase/acetylglutamate synthase
Length = 500
Score = 174 bits (441), Expect = 3e-43
Identities = 118/379 (31%), Positives = 182/379 (47%), Gaps = 103/379 (27%)
Query: 179 IDKVFLISKYGGLPSVERHT-NSHVFVNLSQEYRELRNSYQNQLEKLESIQVDNTEKNLV 237
+D++ ++ K GG+P +R T +SHV +NL+QE+ EL +
Sbjct: 216 VDRIVILDKNGGMPCSKRQTGSSHVLINLAQEFDELAKTLPPY----------------- 258
Query: 238 ESLQLFLNQDKILSNSDQLKCHMEDLEIMNKTLSVLPHSSTGLITT---ILAGSKLSDNN 294
H ++L ++ + L +LP ++ LITT + + + D N
Sbjct: 259 ---------------------HRKNLILVRRCLKMLPDDASALITTPEDAMLTNPVLDKN 297
Query: 295 PLVYNILTDRSLISSSLPRFKRSAAAQSKSWYELPSSNVEEEVTSANDSVLVTTVFKKGI 354
PL++N+LTDRS+IS SLPR + + TTV + G+
Sbjct: 298 PLIHNVLTDRSIISCSLPRDR--------------------------SPITKTTVLRSGV 331
Query: 355 DIHIFDFRTLTDDNSIGLPPSQATQTGKSDPVSKKLDLNKLNGIINSSFKRSLDLSHYLG 414
++ F D S+ +L +IN SFKR+LD+ YL
Sbjct: 332 PVYTFLGPKCLTDGSVSW--------------------ERLWVLINDSFKRTLDMDAYLD 371
Query: 415 RINGNIASIIVIGDYEGIAILTYEGPK---DKQFVYLDKFAVAQKLKGSLGISDIIFNLM 471
R+ ++A++I+ GDY G AI+TYE P +++ YLDK AV+Q +GS ISD++FN+M
Sbjct: 372 RLKNSLAAVIIAGDYLGTAIVTYEQPDGTTNEKVPYLDKLAVSQGAQGSAAISDVMFNVM 431
Query: 472 FRKFPHELIWRSREDNVVNKWYFQRSTGVLHLSLDLGNDDQKQSIFKLFYYGNPESESFH 531
FP ELIWRSR N VNKWYF+RS G L S ++ +KLF+ G+
Sbjct: 432 TDLFPKELIWRSRLTNPVNKWYFERSVGSLKSS---------KTPWKLFWTGD---SHVR 479
Query: 532 NVERLRDYAKYVRDITPSW 550
N++R+ Y + I P+W
Sbjct: 480 NLDRVNQYMSVIDKIQPTW 498
>Hs20559071 [E] KOG2436 Acetylglutamate kinase/acetylglutamate synthase
Length = 376
Score = 53.9 bits (128), Expect = 6e-07
Identities = 41/119 (34%), Positives = 56/119 (46%), Gaps = 12/119 (10%)
Query: 389 KLDLNKLNGIINSSFKRSLDLSHYLGRINGNIASIIV--------IGDYEGIAILTYEGP 440
KLD +L ++N+SF + L YL + + SI V Y AILT E P
Sbjct: 219 KLDQGRLVDLVNASFGKKLR-DDYLASLRPRLHSIYVSEGLPLSRCARYNAAAILTME-P 276
Query: 441 KDKQFVYLDKFAVAQKLKGSLGISDIIFNLMFRKFPHELIWRSREDNVVNKWYFQRSTG 499
YLDKF V+ +G G +++ + R L WRSR N +N WYF+ S G
Sbjct: 277 VLGGTPYLDKFVVSSSRQGQ-GSGQMLWECLRRDL-QTLFWRSRVTNPINPWYFKHSDG 333
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.317 0.135 0.385
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 31,766,428
Number of Sequences: 60738
Number of extensions: 1324155
Number of successful extensions: 3941
Number of sequences better than 1.0e-05: 3
Number of HSP's better than 0.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 1
Number of HSP's that attempted gapping in prelim test: 3923
Number of HSP's gapped (non-prelim): 6
length of query: 552
length of database: 30,389,216
effective HSP length: 111
effective length of query: 441
effective length of database: 23,647,298
effective search space: 10428458418
effective search space used: 10428458418
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)