ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIV1717 check: MH L KOG1968 Replication, recombination and repair Replication factor C, subunit RFC1 (large subunit)
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIV1717 592913 595417 835
(835 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YOR217w [L] KOG1968 Replication factor C subunit RFC1 (large sub... 814 0.0
SPBC23E6.07c [L] KOG1968 Replication factor C subunit RFC1 (larg... 484 e-136
7296805 [L] KOG1968 Replication factor C subunit RFC1 (large sub... 325 2e-88
Hs15011931 [L] KOG1968 Replication factor C subunit RFC1 (large ... 296 1e-79
ECU05g1530 [L] KOG1968 Replication factor C subunit RFC1 (large ... 241 3e-63
CE20613 [L] KOG1968 Replication factor C subunit RFC1 (large sub... 216 2e-55
SPBC902.02c [DL] KOG1969 DNA replication checkpoint protein CHL1... 102 3e-21
YMR078c [DL] KOG1969 DNA replication checkpoint protein CHL12/CTF18 84 7e-16
CE17139 [L] KOG0991 Replication factor C subunit RFC2 80 2e-14
CE06149 [DL] KOG1969 DNA replication checkpoint protein CHL12/CTF18 79 3e-14
At1g63160 [L] KOG0991 Replication factor C subunit RFC2 79 4e-14
Hs14777079 [DL] KOG1969 DNA replication checkpoint protein CHL12... 77 8e-14
YOL094c [L] KOG0991 Replication factor C subunit RFC2 77 1e-13
SPAC1687.03c [L] KOG0991 Replication factor C subunit RFC2 77 1e-13
7292439 [L] KOG0991 Replication factor C subunit RFC2 74 1e-12
Hs4506487 [L] KOG0991 Replication factor C subunit RFC2 72 3e-12
ECU09g1330 [L] KOG0991 Replication factor C subunit RFC2 72 4e-12
YNL290w [L] KOG0990 Replication factor C subunit RFC5 71 8e-12
ECU01g1180 [L] KOG1968 Replication factor C subunit RFC1 (large ... 71 8e-12
At1g77620 [L] KOG1968 Replication factor C subunit RFC1 (large s... 70 2e-11
At1g04730 [DL] KOG1969 DNA replication checkpoint protein CHL12/... 68 5e-11
ECU02g0290 [L] KOG0990 Replication factor C subunit RFC5 65 6e-10
YJR068w [L] KOG0989 Replication factor C subunit RFC4 62 4e-09
CE01268 [L] KOG0989 Replication factor C subunit RFC4 61 6e-09
7295770 [DL] KOG1969 DNA replication checkpoint protein CHL12/CTF18 59 2e-08
Hs4506383 [DL] KOG1970 Checkpoint RAD17-RFC complex RAD17/RAD24 ... 59 3e-08
Hs19718786 [DL] KOG1970 Checkpoint RAD17-RFC complex RAD17/RAD24... 59 3e-08
At1g21690 [L] KOG0989 Replication factor C subunit RFC4 57 9e-08
Hs4506491 [L] KOG0989 Replication factor C subunit RFC4 57 2e-07
Hs6677723 [L] KOG0990 Replication factor C subunit RFC5 56 2e-07
ECU02g0680 [L] KOG0989 Replication factor C subunit RFC4 56 2e-07
SPAC23D3.02 [L] KOG0989 Replication factor C subunit RFC4 54 8e-07
At1g77470 [L] KOG0990 Replication factor C subunit RFC5 52 5e-06
>YOR217w [L] KOG1968 Replication factor C subunit RFC1 (large subunit)
Length = 861
Score = 814 bits (2103), Expect = 0.0
Identities = 428/733 (58%), Positives = 526/733 (71%), Gaps = 19/733 (2%)
Query: 60 SNTTAADEKEQSPAKKPRIS---EPSSNGLTKPDVSRVKKSDSPQTVKELLDSIPSVDLD 116
S T ++K PAK+ S +P+S+ TKP S+ S S T +++LD IPS+DL
Sbjct: 61 SETPEGEKKLPLPAKRKASSPTVKPASSKKTKPS-SKSSDSASNITAQDVLDKIPSLDLS 119
Query: 117 NVTTKEATQFSWKXXXXXXXXXXXELEI---PEGQANCLLGLTIVFTGTLPNLDRSTSEN 173
NV KE +F +K EI PEG+ NCLLGLTIVFTG LP L+R SE
Sbjct: 120 NVHVKENAKFDFKSANSNADPDEIVSEIGSFPEGKPNCLLGLTIVFTGVLPTLERGASEA 179
Query: 174 LAKRYGARVTKSISKNTSVVVLGEEAGPKKLENIKKLGIKAIDEEGFKRLIAGMPAGGGD 233
LAKRYGARVTKSIS TSVVVLG+EAGPKKLE IK+L IKAIDEEGFK+LIAGMPA GGD
Sbjct: 180 LAKRYGARVTKSISSKTSVVVLGDEAGPKKLEKIKQLKIKAIDEEGFKQLIAGMPAEGGD 239
Query: 234 NQQADKARRKLXXXXXXXXXXXXXXXXXXXXXXXXDKLSVGKDVNLSSKSTVTEDSKLWT 293
+ A+KARRKL + +L + V E+ KLWT
Sbjct: 240 GEAAEKARRKLEEQHNIATKEAELLVKKEEERSKKLAATRVSGGHLERDNVVREEDKLWT 299
Query: 294 TKYAPTDLRQLCGNKGAIQKLKTWLESWSSGKKPSM-----------RAVMLSGPPGIGK 342
KYAPT+L+Q+CGNKG++ KLK WL +W + KK S RA ML GPPGIGK
Sbjct: 300 VKYAPTNLQQVCGNKGSVMKLKNWLANWENSKKNSFKHAGKDGSGVFRAAMLYGPPGIGK 359
Query: 343 TTAAHLVAKSLGYDVLEKNASDVRSKGLLNASVKFALDHKSVIGMFKSISDDHYSKNGKR 402
TTAAHLVA+ LGYD+LE+NASDVRSK LLNA VK ALD+ SV+G FK +++ + NGK
Sbjct: 360 TTAAHLVAQELGYDILEQNASDVRSKTLLNAGVKNALDNMSVVGYFKH-NEEAQNLNGKH 418
Query: 403 FVIIMDEXXXXXXXXXXXXXQLAQYCRKTNTPMILICNERNLPKMRPFDHSVLDIPFRRP 462
FVIIMDE QLAQ+CRKT+TP+ILICNERNLPKMRPFD LDI FRRP
Sbjct: 419 FVIIMDEVDGMSGGDRGGVGQLAQFCRKTSTPLILICNERNLPKMRPFDRVCLDIQFRRP 478
Query: 463 DAQAVKARLMTIAMREKFKLDPNVIDRLVSVTRGDMRQIINLLSTVTTTSKSIGSDNIKS 522
DA ++K+RLMTIA+REKFKLDPNVIDRL+ TRGD+RQ+INLLST++TT+K+I +NI
Sbjct: 479 DANSIKSRLMTIAIREKFKLDPNVIDRLIQTTRGDIRQVINLLSTISTTTKTINHENINE 538
Query: 523 LSDNWEKNVALKIFDITPKLLSGGIYTENGAKQFPLYKKMELYFDDFDFTPLMIQENYTS 582
+S WEKN+ALK FDI K+L G IY++ G++ F L K+ LYFDDFDFTPLMIQENY S
Sbjct: 539 ISKAWEKNIALKPFDIAHKMLDGQIYSDIGSRNFTLNDKIALYFDDFDFTPLMIQENYLS 598
Query: 583 TTPTLLRKGQTHLNAVAAAAESISEGDLVDKKIRSAEQQWSLLPLHAVLSTVRPASMVAG 642
T P++L+ GQ+HL AVA AA IS GD+V+KKIRS+EQ WSLLPLHAVLS+V PAS VAG
Sbjct: 599 TRPSVLKPGQSHLEAVAEAANCISLGDIVEKKIRSSEQLWSLLPLHAVLSSVYPASKVAG 658
Query: 643 NVTRRINFSAFLGQNSKTGKFYRLLQDIQYHTRLSTSTNKMGLRLQYMPTMKRHLLDPLL 702
++ RINF+A+LGQNSK+ K+YRLLQ+I YHTRL TST+K+GLRL Y+PT ++ LLDP L
Sbjct: 659 HMAGRINFTAWLGQNSKSAKYYRLLQEIHYHTRLGTSTDKIGLRLDYLPTFRKRLLDPFL 718
Query: 703 RDGSAAIENVINFMDDYYLSKDHWDSIMQFYVGTDDTTAALKSIPSSTKSAFTRAYNNVS 762
+ G+ AI +VI MDDYYL+K+ WDSIM+F+VG D TTA +K IP++ KS FTR YN+++
Sbjct: 719 KQGADAISSVIEVMDDYYLTKEDWDSIMEFFVGPDVTTAIIKKIPATVKSGFTRKYNSMT 778
Query: 763 HPTPIMKLGVSTG 775
HP I + G + G
Sbjct: 779 HPVAIYRTGSTIG 791
>SPBC23E6.07c [L] KOG1968 Replication factor C subunit RFC1 (large subunit)
Length = 934
Score = 484 bits (1247), Expect = e-136
Identities = 279/725 (38%), Positives = 407/725 (55%), Gaps = 48/725 (6%)
Query: 62 TTAADEKEQSPAKKPRISEPSSNGLTKPD-VSRVKKSDS----PQTVKELLDSIPSVDLD 116
T A + Q A+K S+ S+ T SR KS V + L ++P +D+D
Sbjct: 149 TRATRKPAQPKAEKSTTSKSKSHTTTATTHTSRSSKSKGLPRFSDEVSQALKNVPLIDVD 208
Query: 117 NVTTKEATQFSWKXXXXXXXXXXXELEIPEGQANCLLGLTIVFTGTLPNLDRSTSENLAK 176
++ F + +PEG ++CL G++ V TG L L R + +L K
Sbjct: 209 SMGVMAPGTFYERAATTQTPGSK---PVPEGNSDCLSGISFVITGILETLTRQEATDLIK 265
Query: 177 RYGARVTKSISKNTSVVVLGEEAGPKKLENIKKLGIKAIDEEGFKRLIAGMPAGGGDNQQ 236
+YG +VT + S T ++LGE AGP+K+E IK+ I AI+E+G LI +PA GG
Sbjct: 266 QYGGKVTGAPSVRTDFILLGENAGPRKVETIKQHKIPAINEDGLFYLITHLPASGGTGAA 325
Query: 237 ADKARRKLXXXXXXXXXXXXXXXXXXXXXXXXDKLSVGKDVNLSSKSTVTEDSKLWTTKY 296
A A++K S ++ S++WT+KY
Sbjct: 326 AQAAQQKKEQEEKKILETVARMD--------------------DSNKKESQPSQIWTSKY 365
Query: 297 APTDLRQLCGNKGAIQKLKTWLESWSSGKKPSM-----------RAVMLSGPPGIGKTTA 345
APT L+ +CGNKG +QKL+ WL+ + +K + +AV+LSGPPGIGKTTA
Sbjct: 366 APTSLKDICGNKGVVQKLQKWLQDYHKNRKSNFNKPGPDGLGLYKAVLLSGPPGIGKTTA 425
Query: 346 AHLVAKSLGYDVLEKNASDVRSKGLLNASVKFALDHKSVIGMFKSISDDHYSKNGKRFVI 405
AHLVAK GYDVLE NASD RSK LL+ + D +S+ G F + ++ R V+
Sbjct: 426 AHLVAKLEGYDVLELNASDTRSKRLLDEQLFGVTDSQSLAGYFGTKANP-VDMAKSRLVL 484
Query: 406 IMDEXXXXXXXXXXXXXQLAQYCRKTNTPMILICNERNLPKMRPFDHSVLDIPFRRPDAQ 465
IMDE QL +K+ P+I ICN+R PK+RP D + D+ FRRPDA
Sbjct: 485 IMDEIDGMSSGDRGGVGQLNMIIKKSMIPIICICNDRAHPKLRPLDRTTFDLRFRRPDAN 544
Query: 466 AVKARLMTIAMREKFKLDPNVIDRLVSVTRGDMRQIINLLSTVTTTSKSIGSDNIKSLSD 525
++++R+M+IA RE KL P +D+LV T+ DMRQIINLLST + + N +++
Sbjct: 545 SMRSRIMSIAYREGLKLSPQAVDQLVQGTQSDMRQIINLLSTYKLSCSEMTPQNSQAVIK 604
Query: 526 NWEKNVALKIFDITPKLLSGGIYTENGAKQFPLYKKMELYFDDFDFTPLMIQENYTSTTP 585
N EK++ +K +DI + L GG++ + + + + K+ELYF+D +F+ LM+QENY +TTP
Sbjct: 605 NSEKHIVMKPWDICSRYLHGGMF--HPSSKSTINDKLELYFNDHEFSYLMVQENYLNTTP 662
Query: 586 TLLRKGQT------HLNAVAAAAESISEGDLVDKKIRSAEQQWSLLPLHAVLSTVRPASM 639
+R+ HL +++AA S S+ DLVD I +Q WSL+P HA++S VRPAS
Sbjct: 663 DRIRQEPPKMSHLKHLELISSAANSFSDSDLVDSMIHGPQQHWSLMPTHALMSCVRPASF 722
Query: 640 VAGNVTRRINFSAFLGQNSKTGKFYRLLQDIQYHTRLSTSTNKMGLRLQYMPTMKRHLLD 699
VAG+ +R+I F+ +LG NSKT K YR+L++IQ H RL S NK+ LR Y+P + L
Sbjct: 723 VAGSGSRQIRFTNWLGNNSKTNKLYRMLREIQVHMRLKVSANKLDLRQHYIPILYESLPV 782
Query: 700 PLLRDGSAAIENVINFMDDYYLSKDHWDSIMQFYVGTDDTTAALKSIPSSTKSAFTRAYN 759
L S + +I MD+YYL+++ +DSI + + D +K+IP++ KSAFTR YN
Sbjct: 783 KLSTGHSDVVPEIIELMDEYYLNREDFDSITELVLPADAGEKLMKTIPTAAKSAFTRKYN 842
Query: 760 NVSHP 764
+ SHP
Sbjct: 843 SSSHP 847
>7296805 [L] KOG1968 Replication factor C subunit RFC1 (large subunit)
Length = 986
Score = 325 bits (833), Expect = 2e-88
Identities = 234/776 (30%), Positives = 355/776 (45%), Gaps = 104/776 (13%)
Query: 68 KEQSPAKKPRI---SEPSSNGL--TKPDVSRVKKSDSPQTVKELLDSIPSVDLDNVTTKE 122
KE +P KK S PS + P+ + K + S T + P+ DL++ +
Sbjct: 139 KEAAPEKKVHSITRSSPSPKRAKNSSPEPPKPKSTKSKATTPRVKKEKPAADLESSVLTD 198
Query: 123 ATQFSWKXXXXXXXXXXXEL---------EIPEGQANCLLGLTIVFTGTLPNLDRSTSEN 173
+ K EIP+G +CL GLT V TG L +++R +E+
Sbjct: 199 EERHERKRASAVLYQKYKNRSSCLNPGSKEIPKGSPDCLSGLTFVVTGVLESMEREEAES 258
Query: 174 LAKRYGARVTKSISKNTSVVVLGEEAGPKKLENIKKLGIKAIDEEGFKRLIAG------- 226
+ K YG +V + K +V+GEEAGPKKL ++L I + E+G LI
Sbjct: 259 VIKEYGGKVMTVVGKKLKYLVVGEEAGPKKLAVAEELNIPILSEDGLFDLIREKSGIAKQ 318
Query: 227 ---------------------MPAGGGDNQQADKARRKLXXXXXXXXXXXXXXXXXXXXX 265
+ + + +K KL
Sbjct: 319 VKEEKKSPKKEHSSEEKGKKEVKTSRRSSDKKEKEATKLKYGEKHDIAKHKVKEEHTSPK 378
Query: 266 XXXDKLSVGKDVNLSSK-----------STVTEDSKL-------WTTKYAPTDLRQLCGN 307
DKL+ V L K S T D K W K+ PT ++++ G
Sbjct: 379 ETKDKLNDVPAVTLKVKKEPSSQKEHPPSPRTADLKTLDVVGMAWVDKHKPTSIKEIVGQ 438
Query: 308 KGA---IQKLKTWLESW----SSGKKPSM-------------RAVMLSGPPGIGKTTAAH 347
GA + KL WL W KKP +A +LSGPPGIGKTT A
Sbjct: 439 AGAASNVTKLMNWLSKWYVNHDGNKKPQRPNPWAKNDDGSFYKAALLSGPPGIGKTTTAT 498
Query: 348 LVAKSLGYDVLEKNASDVRSKGLLNASVKFALDHKSVIGMFKSISDDHYSKNGKRFVIIM 407
LV K LG+D +E NASD RSK LL V L +KS+ G F ++ V+IM
Sbjct: 499 LVVKELGFDAVEFNASDTRSKRLLKDEVSTLLSNKSLSGYFTGQGQ----AVSRKHVLIM 554
Query: 408 DEXXXXXXXXXXXXXQ-LAQYCRKTNTPMILICNERNLPKMRPFDHSVLDIPFRRPDAQA 466
DE Q L + ++ P+I +CN+RN PK+R + D+ F+RP +
Sbjct: 555 DEVDGMAGNEDRGGMQELIALIKDSSIPIICMCNDRNHPKIRSLVNYCYDLRFQRPRLEQ 614
Query: 467 VKARLMTIAMREKFKLDPNVIDRLVSVTRGDMRQIIN---LLSTVTTTSKSIGSDNIKSL 523
+K ++M+I +EK K+ P ++ +++ T D+RQ IN LLS S+ G
Sbjct: 615 IKGKIMSICFKEKVKISPAKVEEIIAATNNDIRQSINHIALLSAKEDASQKSG------- 667
Query: 524 SDNWEKNVALKIFDITPKLLSGGIYTENGAKQFPLYKKMELYFDDFDFTPLMIQENYTST 583
+ VA K + P + ++T + K K +L+F D+ PL +Q+NY
Sbjct: 668 -----QQVATKDLKLGPWEVVRKVFTADEHKHMSFADKSDLFFHDYSLAPLFVQQNYLQV 722
Query: 584 TPTLLRKGQTHLNAVAAAAESISEGDLVDKKIRSAEQQWSLLPLHAVLSTVRPASMVAGN 643
P +K L VAA A+++S GDLV+K+IR A WSLLP A S+V P + G+
Sbjct: 723 LPQGNKKDV--LAKVAATADALSLGDLVEKRIR-ANSAWSLLPTQAFFSSVLPGEHMCGH 779
Query: 644 VTRRINFSAFLGQNSKTGKFYRLLQDIQYHTRLSTSTNKMGLRLQYMPTMKRHLLDPLLR 703
T +INF +LG+NSK+GK RL Q++ HTR+ TS +++ +RL Y P + +++ PL +
Sbjct: 780 FTGQINFPGWLGKNSKSGKRARLAQELHDHTRVCTSGSRLSVRLDYAPFLLDNIVRPLAK 839
Query: 704 DGSAAIENVINFMDDYYLSKDHWDSIMQFYVGTDDTTAALKSIPSSTKSAFTRAYN 759
DG + ++ M DY+L ++ DS+++ + L ++ K+A TR+YN
Sbjct: 840 DGQEGVPAALDVMKDYHLLREDLDSLVEL-TSWPGKKSPLDAVDGRVKAALTRSYN 894
>Hs15011931 [L] KOG1968 Replication factor C subunit RFC1 (large subunit)
Length = 1148
Score = 296 bits (757), Expect = 1e-79
Identities = 229/818 (27%), Positives = 368/818 (43%), Gaps = 81/818 (9%)
Query: 24 SPKKPKKVKSQAAETIXXXXXXXXXXXXASQPRRSRSNTTAADEKEQSPAKK--PRISEP 81
SP+K K +S + E+ S P+ S S KE+S K+ P S+
Sbjct: 283 SPRKQSKYES-SKESQQHSKSSADKIGEVSSPKAS-SKLAIMKRKEESSYKEIEPVASKR 340
Query: 82 SSNGLT-KPDVSRVKKSDSPQTVKELLDSIPSVDLDNVTTKEATQFSWKXXXXXXXXXXX 140
N + K + KK+ S KE S+ D + T S+
Sbjct: 341 KENAIKLKGETKTPKKTKSSPAKKE---SVSPEDSEKKRTNYQAYRSYLNREGPKALGSK 397
Query: 141 ELEIPEGQANCLLGLTIVFTGTLPNLD-----------------------------RSTS 171
E IP+G NCL GL V TG L +++ R +
Sbjct: 398 E--IPKGAENCLEGLIFVITGVLESIERDEAKSLIERYGGKVTGNVSKKTNYLVMGRDSG 455
Query: 172 ENLAKRYGARVTKSISKNTSVVVLGEEAGPKKLENI-------KKLGIKAIDEEGF--KR 222
++ + + A TK I ++ + ++ G K I K+ ++ ++ KR
Sbjct: 456 QSKSDKAAALGTKIIDEDGLLNLIRTMPGKKSKYEIAVETEMKKESKLERTPQKNVQGKR 515
Query: 223 LIAGMPAGGGDNQQADKARRKLXXXXXXXXXXXXXXXXXXXXXXXXDKLSVGKDVNLSSK 282
I+ + ++R + K NL+
Sbjct: 516 KISPSKKESESKKSRPTSKRDSLAKTIKKETDVFWKSLDFKEQVAEETSGDSKARNLADD 575
Query: 283 STVTE-DSKLWTTKYAPTDLRQLCGNKG---AIQKLKTWLESWS---------------- 322
S+ + ++ LW KY PT L+ + G +G KL WL +W
Sbjct: 576 SSENKVENLLWVDKYKPTSLKTIIGQQGDQSCANKLLRWLRNWQKSSSEDKKHAAKFGKF 635
Query: 323 SGKKP--SMRAVMLSGPPGIGKTTAAHLVAKSLGYDVLEKNASDVRSKGLLNASVKFALD 380
SGK S +A +LSGPPG+GKTT A LV + LGY +E NASD RSK L A V +L+
Sbjct: 636 SGKDDGSSFKAALLSGPPGVGKTTTASLVCQELGYSYVELNASDTRSKSSLKAIVAESLN 695
Query: 381 HKSVIGMFKSISDDHYSKNGKRFVIIMDEXXXXXXXXXXXXXQ-LAQYCRKTNTPMILIC 439
+ S+ G + S+ S + +IMDE Q L + T P+I +C
Sbjct: 696 NTSIKGFY---SNGAASSVSTKHALIMDEVDGMAGNEDRGGIQELIGLIKHTKIPIICMC 752
Query: 440 NERNLPKMRPFDHSVLDIPFRRPDAQAVKARLMTIAMREKFKLDPNVIDRLVSVTRGDMR 499
N+RN PK+R H D+ F+RP + +K +M+IA +E K+ P ++ ++ D+R
Sbjct: 753 NDRNHPKIRSLVHYCFDLRFQRPRVEQIKGAMMSIAFKEGLKIPPPAMNEIILGANQDIR 812
Query: 500 QIINLLSTVTTTSKSIGSDNIKSLSDNWEKNVALKIFDITPKLLSGGIYTENGAKQFPLY 559
Q+++ LS SK++ D K+ S +K++ + FD+ K+ + G T + L
Sbjct: 813 QVLHNLSMWCARSKALTYDQAKADSHRAKKDIKMGPFDVARKVFAAGEETAH----MSLV 868
Query: 560 KKMELYFDDFDFTPLMIQENYTSTTPTLLRKG-QTHLNAVAAAAESISEGDLVDKKIRSA 618
K +L+F D+ PL +QENY P + HL ++ AA+SI +GDLVD +IRS
Sbjct: 869 DKSDLFFHDYSIAPLFVQENYIHVKPVAAGGDMKKHLMLLSRAADSICDGDLVDSQIRS- 927
Query: 619 EQQWSLLPLHAVLSTVRPASMVAGNVTRRINFSAFLGQNSKTGKFYRLLQDIQYHTRLST 678
+Q WSLLP A+ ++V P ++ G +T+ F ++LG++S TGK R++QD+ H L T
Sbjct: 928 KQNWSLLPAQAIYASVLPGELMRGYMTQFPTFPSWLGKHSSTGKHDRIVQDLALHMSLRT 987
Query: 679 STNKMGLRLQYMPTMKRHLLDPLLRDGSAAIENVINFMDDYYLSKDHWDSIMQFYVGTDD 738
++K + + Y+ ++ L+ PL G +++V+ MD YYL K+ +++IM+
Sbjct: 988 YSSKRTVNMDYLSLLRDALVQPLTSQGVDGVQDVVALMDTYYLMKEDFENIMEI-SSWGG 1046
Query: 739 TTAALKSIPSSTKSAFTRAYNNVSHPTPIMKLGVSTGR 776
+ + K+AFTRAYN +H TP + R
Sbjct: 1047 KPSPFSKLDPKVKAAFTRAYNKEAHLTPYSLQAIKASR 1084
>ECU05g1530 [L] KOG1968 Replication factor C subunit RFC1 (large subunit)
Length = 568
Score = 241 bits (615), Expect = 3e-63
Identities = 182/626 (29%), Positives = 288/626 (45%), Gaps = 96/626 (15%)
Query: 152 LLGLTIVFTGTLPNLDRSTSENLAKRYGARVTKSISKNTSVVVLGEEAGPKKLENIKKLG 211
L G VFTG + + R ++ G R T S T+ +V G+ GP K++ K+LG
Sbjct: 8 LKGKVFVFTGDM-KISRDDAKTKVMVLGGRCTAVPSSKTTFLVAGDNPGPSKMQKAKELG 66
Query: 212 IKAIDEEGFKRLIAGMPAGGGDNQQADKARRKLXXXXXXXXXXXXXXXXXXXXXXXXDKL 271
IK +DEE F LI + +K K
Sbjct: 67 IKVLDEEEFDSLIKDTSKALDGTAEVEKKTEKAA-------------------------- 100
Query: 272 SVGKDVNLSSKSTVTEDSKLWTTKYAPTDLRQLCGNKGAIQKLKTWLESWSSGKKPSMRA 331
S + S +W+ KY P+ ++ GN+G +++L+ +L+ + +A
Sbjct: 101 --------SRDECGSASSGVWSEKYRPSKRDEIVGNQGIVKQLEDYLQG-----RTKYKA 147
Query: 332 VMLSGPPGIGKTTAAHLVAKSLGYDVLEKNASDVRSKGLLNASVKFALDHKSVIGMFKSI 391
V+LSG PGIGKTT AH+V KSLG +V+E NASDVRSK ++ VK + +S++ S
Sbjct: 148 VLLSGQPGIGKTTTAHVVCKSLGLNVIEFNASDVRSKLEISNKVKAFVSSQSILRPGSS- 206
Query: 392 SDDHYSKNGKRFVIIMDEXXXXXXXXXXXXXQLAQYCRKTNTPMILICNERNLPKMRPFD 451
K V+IMDE +L ++T P+I ICN+RN PK+R
Sbjct: 207 ---------KSKVLIMDE-VDGMSSDRGGIPELISIVKETVVPIICICNDRNNPKIRTLS 256
Query: 452 HSVLDIPFRRPDAQAVKARLMTIAMREKFKLDPNVIDRLVSVTRGDMRQIINLLSTVTTT 511
LD+ FR+PDA+ + +R+ I E K+ +++ ++S GD+R I+++ ++
Sbjct: 257 SYCLDLRFRKPDARQILSRVKQILDMEGKKIPDGLLNEIISRGAGDIRYTISMVQSIALR 316
Query: 512 SKSIGSDNIKSLSDNWEKNVALKIFDITPKLLSGGIYTENGAKQFPLYKKMELYFDDFDF 571
+ N+K + KNV +FD+ +G ++ + +K++LYF+D+
Sbjct: 317 K----ALNLKVAENLVRKNVVKNVFDV-----AGEVFQRRS-----ISEKIDLYFEDYSL 362
Query: 572 TPLMIQENYTSTTPTLLRKGQTHLNAVAAAAESISEGDLVDKKIRSAEQQWSLLPLHAVL 631
PL + EN T+ R ++ +SIS GD+V+K IR Q WSL PLHAV
Sbjct: 363 IPLFVSENILKTSFRSARD-------LSECFDSISLGDVVEKLIRGVSQDWSLAPLHAVY 415
Query: 632 STVRPASMVAGNVTRRINFSAFLGQNSKTGKFYRLLQDIQYHTRLSTSTN-------KMG 684
S V P ++ +++ F ++LGQNSK K R+L + H+ N G
Sbjct: 416 SVVVPTK--GRHLMKKLEFPSWLGQNSKHSKAERILHTVSMHSSCKIRNNPEELRKCSSG 473
Query: 685 LRLQ-YMPTMKRHLLDPLLRDGSAAIENVINFMDDYYLSKDHWDSIMQFYVGTDDTTAAL 743
L LQ Y +K H +D AI N++ DY ++K+ + + G D
Sbjct: 474 LILQKYAYYLKTHSID-------KAISNIV----DYDMTKEDIVGLAEIIPGGAD---LF 519
Query: 744 KSIPSSTKSAFTRAYNNVSHPTPIMK 769
K I K R Y + P ++
Sbjct: 520 KGIERKVKLLLDREYKKLKRRLPYIE 545
>CE20613 [L] KOG1968 Replication factor C subunit RFC1 (large subunit)
Length = 839
Score = 216 bits (549), Expect = 2e-55
Identities = 151/514 (29%), Positives = 237/514 (45%), Gaps = 56/514 (10%)
Query: 292 WTTKYAPTDLRQLCGNKG---AIQKLKTWLESWSSG--------KKP------------S 328
W KY P + +L G G I KL W++ W+ KKP S
Sbjct: 280 WVDKYKPKRMGELVGQNGDKSPINKLLEWIKDWAKHNLGEGAKIKKPKPAPWMSSQDGTS 339
Query: 329 MRAVMLSGPPGIGKTTAAHLVAKSLGYDVLEKNASDVRSKGLLNASVKFALDHKSVIGMF 388
+A +LSG PG+GKTT A++ + LG ++E NASDVRSK L A + + F
Sbjct: 340 FKAALLSGSPGVGKTTCAYMACQQLGLQLVEMNASDVRSKKHLEAKIGELSGSHQIEQFF 399
Query: 389 KSISDDHYSKNGKRFVIIMDEXXXXXXXXXXXX-XQLAQYCRKTNTPMILICNERNLPKM 447
+ ++IMDE +L Q +++ P+I ICN+R PK+
Sbjct: 400 GAKKCAPQDNQKVHHILIMDEVDGMSGNEDRAGISELIQIIKESKIPIICICNDRQHPKI 459
Query: 448 RPFDHSVLDIPFRRPDAQAVKARLMTIAMREKFKLDPNVIDRLVSVTRGDMRQIINLLST 507
R + D+ F +P + +++R+MTI +EK K+ +D ++ ++ D+RQ I L
Sbjct: 460 RTLANYCYDLRFPKPRVETIRSRMMTICSQEKMKIGKEELDEIIELSGHDVRQTIYNLQM 519
Query: 508 VTTTSKSIGSDNIKSLSDNWEKNVALKIFDITPKLLSGGIYTENGAKQFPLYKKMELYFD 567
SK +G+ +K++A+ F +LL + L +K E++F
Sbjct: 520 ---RSKGVGAKIN-------QKDMAVDAFSAARRLLDS---------RTTLMEKQEMFFT 560
Query: 568 DFDFTPLMIQENYTSTTPTLLRKGQTH-----LNAVAAAAESISEGDLVDKKIRSAEQQW 622
D+ PL +Q+NY L K + H + + AA+ IS GDL+D++IR W
Sbjct: 561 DYGIMPLFVQDNY------LNMKNEKHSPIQAIRGIRKAADFISLGDLIDRQIRGGGS-W 613
Query: 623 SLLPLHAVLSTVRPASMVAGNVTRRINFSAFLGQNSKTGKFYRLLQDIQYHTRLSTSTNK 682
LL +++S PA G++ I F ++LG+NS GK RLLQ + HT L S
Sbjct: 614 KLLNEQSMISAALPAIATGGHLKAMIQFPSWLGKNSTAGKRKRLLQQLVQHTHLKVSAGT 673
Query: 683 MGLRLQYMPTMKRHLLDPLLRDGSAAIENVINFMDDYYLSKDHWDSIMQFYVGTDDTTAA 742
Y P +++ + PLL + I +VI+ M +Y L KD +++ + A
Sbjct: 674 HSFATDYAPMLRQKITKPLLEHEADGIPDVISTMTEYDLIKDDTEALTEIVAWPGKIDPA 733
Query: 743 LKSIPSSTKSAFTRAYNNVSHPTPIMKLGVSTGR 776
K I S K++ TR N P VS G+
Sbjct: 734 SK-ILSKVKASLTRTLNKTGRMLPYSMDSVSKGK 766
>SPBC902.02c [DL] KOG1969 DNA replication checkpoint protein CHL12/CTF18
Length = 960
Score = 102 bits (253), Expect = 3e-21
Identities = 72/278 (25%), Positives = 116/278 (40%), Gaps = 31/278 (11%)
Query: 277 VNLSSKSTVTEDSKLWTTKYAPTDLRQLCGNKGAIQKLKTWLESW--------------- 321
+ +++ +T + KLW Y P R L G++ + W+++W
Sbjct: 338 LQITNCTTKPQSQKLWVDTYRPQLFRDLLGDERVHRAAMHWIKAWDPCVFGKSRLQPSKS 397
Query: 322 -----------SSGKKPSMRAVMLSGPPGIGKTTAAHLVAKSLGYDVLEKNASDVRSKGL 370
S +P R +ML+G G GKTT AH++A GY VLE NASD R+
Sbjct: 398 MRFNPRFTNITSDSDRPDKRIMMLTGLAGAGKTTLAHVIAHQAGYKVLEINASDDRTAHT 457
Query: 371 LNASVKFAL-DHKSVIGMFKSISDDHYSKNGKRFV----IIMDEXXXXXXXXXXXXXQLA 425
++ V A+ +H ++ + D FV +++ +
Sbjct: 458 VHEKVSSAISNHSALSSQPTCVIVDEIDGGDPAFVRALLSLLESDEKATEYSQAGNSKKK 517
Query: 426 QYCRKTNTPMILICNERNLPKMRPFDHSVLDIPFRRPDAQAVKARLMTIAMREKFKLDPN 485
+ +K P+I ICN+ P +RP I FR P ++ RL TI E +D
Sbjct: 518 KKFKKLCRPIICICNDLYTPALRPLRPYAQIIYFRPPPQASLVGRLRTICRNENIAVDSR 577
Query: 486 VIDRLVSVTRGDMRQIINLLSTVTTTSKSIGSDNIKSL 523
+ L + D+R IN L ++ +K I S+ IK L
Sbjct: 578 SLTLLTDIYNSDIRSCINSLQLLSLNNKRIDSETIKLL 615
>YMR078c [DL] KOG1969 DNA replication checkpoint protein CHL12/CTF18
Length = 741
Score = 84.3 bits (207), Expect = 7e-16
Identities = 80/341 (23%), Positives = 127/341 (36%), Gaps = 45/341 (13%)
Query: 269 DKLSVGKDVNLSSKSTVTEDSK-----LWTTKYAPTDLRQLCGNKGAIQKLKTWLESWSS 323
DK+ D +++ T K LW K+ P L GN+ +++ WL W+
Sbjct: 88 DKIEASGDDRTNAQKTSPITGKIGSDTLWVEKWRPKKFLDLVGNEKTNRRMLGWLRQWTP 147
Query: 324 G-----------------------KKPSMRAVMLSGPPGIGKTTAAHLVAKSLGYDVLEK 360
K+P + ++L GPPGIGKT+ AH++AK G+ V E
Sbjct: 148 AVFKEQLPKLPTEKEVSDMELDPLKRPPKKILLLHGPPGIGKTSVAHVIAKQSGFSVSEI 207
Query: 361 NASDVRS-----KGLLNASVKFALDHKSVIGMFKSISDDHYSKNGKRFVIIMDEXXXXXX 415
NASD R+ + + N D V + I S + V IM
Sbjct: 208 NASDERAGPMVKEKIYNLLFNHTFDTNPVCLVADEIDGSIESGFIRILVDIMQSDIKATN 267
Query: 416 XXXXXXXQLAQYCRK------TNTPMILICNERNLPKMRPFDHSVLDIPFRRPDAQAVKA 469
RK P+I ICN P + I +RP +
Sbjct: 268 KLLYGQPDKKDKKRKKKRSKLLTRPIICICNNLYAPSLEKLKPFCEIIAVKRPSDTTLLE 327
Query: 470 RLMTIAMREKFKLDPNVIDRLVSVTRGDMRQIIN---LLSTVTTTSKSIGSDNIKSLSDN 526
RL I +E + I+ L+ + +GD+R IN L++ + S SD +
Sbjct: 328 RLNLICHKENMNIPIKAINDLIDLAQGDVRNCINNLQFLASNVDSRDSSASDKPACAKNT 387
Query: 527 W---EKNVALKIFDITPKLLSGGIYTENGAKQFPLYKKMEL 564
W K+ + F I +L + + + + L ++EL
Sbjct: 388 WASSNKDSPISWFKIVNQLFRKDPHRDIKEQFYELLNQVEL 428
>CE17139 [L] KOG0991 Replication factor C subunit RFC2
Length = 334
Score = 79.7 bits (195), Expect = 2e-14
Identities = 60/249 (24%), Positives = 105/249 (42%), Gaps = 25/249 (10%)
Query: 292 WTTKYAPTDLRQLCGNKGAIQKLKTWLESWSSGKKPSMRAVMLSGPPGIGKTTAAHLVAK 351
W KY P L + GN+ +++LK G + ++ ++LSGPPG GKTT+ +A+
Sbjct: 12 WVEKYRPKVLADIVGNENIVERLKV------IGHEGNVPNIVLSGPPGCGKTTSVWALAR 65
Query: 352 SLGYD-----VLEKNASDVRSKGLLNASVKFALDHKSVIGMFKSISDDHYSKNGKRFVII 406
L D VLE NASD R ++ +K K + G+ +II
Sbjct: 66 ELLGDKVKEAVLELNASDERGIDVVRHRIKTFAQTKVTL------------PEGRHKIII 113
Query: 407 MDEXXXXXXXXXXXXXQLAQYCRKTNTPMILICNERNLPKMRPFDHSVLDIPFRRPDAQA 466
+DE + + KT T L CN+ + P + + +
Sbjct: 114 LDEADSMTDGAQQALRRTMEMYTKT-TRFALACNQSE-KIIEPIQSRCALLRYTKLSPVQ 171
Query: 467 VKARLMTIAMREKFKLDPNVIDRLVSVTRGDMRQIINLLSTVTTTSKSIGSDNIKSLSDN 526
+ R+ +A EK D ++ ++ +GDMRQ +N L + + +N+ + D
Sbjct: 172 LLTRVKEVAKAEKVNYDDGGLEAILFTAQGDMRQALNNLQATVNAYELVNKENVLKVCDE 231
Query: 527 WEKNVALKI 535
++ +K+
Sbjct: 232 PHPDLMIKM 240
>CE06149 [DL] KOG1969 DNA replication checkpoint protein CHL12/CTF18
Length = 850
Score = 79.0 bits (193), Expect = 3e-14
Identities = 70/297 (23%), Positives = 118/297 (39%), Gaps = 46/297 (15%)
Query: 288 DSKLWTTKYAPTDLRQLCGNKGAIQKLKTWLESWS------------------------- 322
+S LW KY + L + + + TWL+ W
Sbjct: 261 ESSLWVNKYEAKNFSDLLSDSTVNRNILTWLKMWDECVFHQKVDDLLASLGEKEREVLHM 320
Query: 323 -SGK--KPSMRAVMLSGPPGIGKTTAAHLVAKSLGYDVLEKNASDVRSKGLLNASVKFAL 379
+GK +PS + ++LSGP G+GK+T A +VA+ GY ++ NASD R+ LN ++ A+
Sbjct: 321 DNGKIRRPSSKMLLLSGPAGLGKSTLARIVARQAGYSTIDVNASDARTVADLNKVLEGAV 380
Query: 380 DHKSVIGMFKSISDDHYSKNGKRFVIIMDEXXXXXXXXXXXXXQLAQYCRK--TNTPMIL 437
+ + + +I+DE + Q K P+I
Sbjct: 381 KTSRTL-----------DADQRPACLILDEIDGTPIDTIRHLVRCIQATGKKAIRRPIIG 429
Query: 438 ICNERNLPKMRPFDHSVLDIPFRRPDAQAVKARLMTIAMREKFKLDPNVIDRLVSVTRGD 497
ICN P +R + + RL I RE+ + D + + +L + D
Sbjct: 430 ICNNLYTPALRDLRGVAWCVQLVATKQDVLAKRLEEICDRERLRCDLSTLRKLCELCAND 489
Query: 498 MRQIINLLSTVTT----TSKSIGSDNIKSLSDNWEKNVALKIFDITPKLLSGGIYTE 550
MR IN L V ++++IG I + + EK + IF+ +L +T+
Sbjct: 490 MRHSINTLQWVAVAARKSNRAIGMKLIHEVIEK-EKGGSASIFEHWSSILELSKHTD 545
>At1g63160 [L] KOG0991 Replication factor C subunit RFC2
Length = 333
Score = 78.6 bits (192), Expect = 4e-14
Identities = 72/274 (26%), Positives = 114/274 (41%), Gaps = 35/274 (12%)
Query: 280 SSKSTVTED--SKLWTTKYAPTDLRQLCGNKGAIQKLKTWLESWSSGKKPSMRAVMLSGP 337
SS ST T D ++ W KY P+ + + GN+ A+ +L+ G P++ +LSGP
Sbjct: 3 SSSSTSTGDGYNEPWVEKYRPSKVVDIVGNEDAVSRLQVIARD---GNMPNL---ILSGP 56
Query: 338 PGIGKTTA----AH-LVAKSLGYDVLEKNASDVRSKGLLNASVKFALDHKSVIGMFKSIS 392
PG GKTT+ AH L+ + VLE NASD R ++ +K K +
Sbjct: 57 PGTGKTTSILALAHELLGTNYKEAVLELNASDDRGIDVVRNKIKMFAQKKVTL------- 109
Query: 393 DDHYSKNGKRFVIIMDEXXXXXXXXXXXXXQLAQYCRKTNTPMILICNERNLPKMRPFDH 452
G+ V+I+DE + + +T L CN + + P
Sbjct: 110 -----PPGRHKVVILDEADSMTSGAQQALRRTIEIY-SNSTRFALACNT-SAKIIEPIQS 162
Query: 453 SVLDIPFRRPDAQAVKARLMTIAMREKFKLDPNVIDRLVSVTRGDMRQIINLLSTVTTTS 512
+ F R Q + RL+ + EK P ++ ++ GDMRQ +N L +
Sbjct: 163 RCALVRFSRLSDQQILGRLLVVVAAEKVPYVPEGLEAIIFTADGDMRQALNNLQATFSGF 222
Query: 513 KSIGSDNIKSLSD--------NWEKNVALKIFDI 538
+ +N+ + D N +NV FDI
Sbjct: 223 SFVNQENVFKVCDQPHPLHVKNIVRNVLESKFDI 256
>Hs14777079 [DL] KOG1969 DNA replication checkpoint protein CHL12/CTF18
Length = 1003
Score = 77.4 bits (189), Expect = 8e-14
Identities = 58/221 (26%), Positives = 91/221 (40%), Gaps = 40/221 (18%)
Query: 312 QKLKTWLESW-SSGKKPSMRAVMLSGPPGIGKTTAAHLVAKSLGYDVLEKNASDVRSKGL 370
Q L+ LE+ ++P + +L GPPG+GKTT AH++A+ GY V+E NASD RS +
Sbjct: 377 QVLEEMLEAGLDPSQRPKQKVALLCGPPGLGKTTLAHVIARHAGYSVVEMNASDDRSPEV 436
Query: 371 LNASVKFALDHKSVIGMFKSISDDHYSKNGKRFVIIMDEXXXXXXXXXXXXXQLAQYCRK 430
++ A +SV+G GK +++DE + RK
Sbjct: 437 FRTRIEAATQMESVLG-----------AGGKPNCLVIDEIDGAPVAAINVLLSILN--RK 483
Query: 431 --------------------------TNTPMILICNERNLPKMRPFDHSVLDIPFRRPDA 464
P+I ICN++ P +R + F
Sbjct: 484 GPQEVGPQGPAVPSGGGRRRRAEGGLLMRPIICICNDQFAPSLRQLKQQAFLLHFPPTLP 543
Query: 465 QAVKARLMTIAMREKFKLDPNVIDRLVSVTRGDMRQIINLL 505
+ RL +++R+ + DP V+ L T D+R IN L
Sbjct: 544 SRLVQRLQEVSLRQGMRADPGVLAALCEKTDNDIRACINTL 584
>YOL094c [L] KOG0991 Replication factor C subunit RFC2
Length = 323
Score = 77.0 bits (188), Expect = 1e-13
Identities = 61/240 (25%), Positives = 99/240 (40%), Gaps = 25/240 (10%)
Query: 292 WTTKYAPTDLRQLCGNKGAIQKLKTWLESWSSGKKPSMRAVMLSGPPGIGKTTAAH---- 347
W KY P L + GNK I +L+ K +M +++SG PGIGKTT+ H
Sbjct: 11 WVEKYRPQVLSDIVGNKETIDRLQ------QIAKDGNMPHMIISGMPGIGKTTSVHCLAH 64
Query: 348 -LVAKSLGYDVLEKNASDVRSKGLLNASVKFALDHKSVIGMFKSISDDHYSKNGKRFVII 406
L+ +S VLE NASD R ++ +K K + GK ++I
Sbjct: 65 ELLGRSYADGVLELNASDDRGIDVVRNQIKHFAQKKL------------HLPPGKHKIVI 112
Query: 407 MDEXXXXXXXXXXXXXQLAQYCRKTNTPMILICNERNLPKMRPFDHSVLDIPFRRPDAQA 466
+DE + + +T CN+ N + P + + + +
Sbjct: 113 LDEADSMTAGAQQALRRTMELY-SNSTRFAFACNQSN-KIIEPLQSRCAILRYSKLSDED 170
Query: 467 VKARLMTIAMREKFKLDPNVIDRLVSVTRGDMRQIINLLSTVTTTSKSIGSDNIKSLSDN 526
V RL+ I E K + ++ ++ GDMRQ IN L + + +DN+ + D+
Sbjct: 171 VLKRLLQIIKLEDVKYTNDGLEAIIFTAEGDMRQAINNLQSTVAGHGLVNADNVFKIVDS 230
>SPAC1687.03c [L] KOG0991 Replication factor C subunit RFC2
Length = 342
Score = 76.6 bits (187), Expect = 1e-13
Identities = 64/239 (26%), Positives = 100/239 (41%), Gaps = 25/239 (10%)
Query: 292 WTTKYAPTDLRQLCGNKGAIQKLKTWLESWSSGKKPSMRAVMLSGPPGIGKTTA----AH 347
W KY P L + GN+ I +LK K+ +M +++SG PGIGKTT+ AH
Sbjct: 23 WVEKYRPIVLDDIVGNEETIDRLKV------IAKEGNMPHLVISGMPGIGKTTSILCLAH 76
Query: 348 -LVAKSLGYDVLEKNASDVRSKGLLNASVKFALDHKSVIGMFKSISDDHYSKNGKRFVII 406
L+ + VLE NASD R ++ +K K ++ G+ +II
Sbjct: 77 ALLGPAYKEGVLELNASDERGIDVVRNRIKAFAQKKVIL------------PPGRHKIII 124
Query: 407 MDEXXXXXXXXXXXXXQLAQYCRKTNTPMILICNERNLPKMRPFDHSVLDIPFRRPDAQA 466
+DE + + T T L CN+ N + P + + R Q
Sbjct: 125 LDEADSMTAGAQQALRRTMEIYSNT-TRFALACNQSN-KIIEPIQSRCAILRYSRLTDQQ 182
Query: 467 VKARLMTIAMREKFKLDPNVIDRLVSVTRGDMRQIINLLSTVTTTSKSIGSDNIKSLSD 525
V RL+ I EK + + L+ GDMRQ +N L + + +N+ ++D
Sbjct: 183 VLQRLLNICKAEKVNYTDDGLAALIMTAEGDMRQAVNNLQSTVAGFGLVNGENVFRVAD 241
>7292439 [L] KOG0991 Replication factor C subunit RFC2
Length = 331
Score = 73.6 bits (179), Expect = 1e-12
Identities = 57/239 (23%), Positives = 101/239 (41%), Gaps = 25/239 (10%)
Query: 292 WTTKYAPTDLRQLCGNKGAIQKLKTWLESWSSGKKPSMRAVMLSGPPGIGKTTAAHLVAK 351
W KY P +++ GN+ + +L + + G P+ ++++GPPG+GKTT +A+
Sbjct: 18 WIEKYRPVKFKEIVGNEDTVARLSVFA---TQGNAPN---IIIAGPPGVGKTTTIQCLAR 71
Query: 352 SLGYD-----VLEKNASDVRSKGLLNASVKFALDHKSVIGMFKSISDDHYSKNGKRFVII 406
L D VLE NAS+ R ++ +K K + G+ ++I
Sbjct: 72 ILLGDSYKEAVLELNASNERGIDVVRNKIKMFAQQKVTL------------PRGRHKIVI 119
Query: 407 MDEXXXXXXXXXXXXXQLAQYCRKTNTPMILICNERNLPKMRPFDHSVLDIPFRRPDAQA 466
+DE + + T T L CN + P + F +
Sbjct: 120 LDEADSMTEGAQQALRRTMEIYSST-TRFALACNTSE-KIIEPIQSRCAMLRFTKLSDAQ 177
Query: 467 VKARLMTIAMREKFKLDPNVIDRLVSVTRGDMRQIINLLSTVTTTSKSIGSDNIKSLSD 525
V A+L+ +A EK + ++ +V +GDMRQ +N L + I ++N+ + D
Sbjct: 178 VLAKLIEVAKWEKLNYTEDGLEAIVFTAQGDMRQGLNNLQSTAQGFGDITAENVFKVCD 236
>Hs4506487 [L] KOG0991 Replication factor C subunit RFC2
Length = 354
Score = 72.4 bits (176), Expect = 3e-12
Identities = 56/239 (23%), Positives = 102/239 (42%), Gaps = 25/239 (10%)
Query: 292 WTTKYAPTDLRQLCGNKGAIQKLKTWLESWSSGKKPSMRAVMLSGPPGIGKTT-----AA 346
W KY P L ++ GN+ + +L+ + G P+ ++++GPPG GKTT A
Sbjct: 38 WVEKYRPVKLNEIVGNEDTVSRLEVFARE---GNVPN---IIIAGPPGTGKTTSILCLAR 91
Query: 347 HLVAKSLGYDVLEKNASDVRSKGLLNASVKFALDHKSVIGMFKSISDDHYSKNGKRFVII 406
L+ +L +LE NAS+ R ++ +K K + G+ +II
Sbjct: 92 ALLGPALKDAMLELNASNDRGIDVVRNKIKMFAQQKVTL------------PKGRHKIII 139
Query: 407 MDEXXXXXXXXXXXXXQLAQYCRKTNTPMILICNERNLPKMRPFDHSVLDIPFRRPDAQA 466
+DE + + KT T L CN + + P + + +
Sbjct: 140 LDEADSMTDGAQQALRRTMEIYSKT-TRFALACNASD-KIIEPIQSRCAVLRYTKLTDAQ 197
Query: 467 VKARLMTIAMREKFKLDPNVIDRLVSVTRGDMRQIINLLSTVTTTSKSIGSDNIKSLSD 525
+ RLM + +E+ + ++ ++ +GDMRQ +N L + + I S+N+ + D
Sbjct: 198 ILTRLMNVIEKERVPYTDDGLEAIIFTAQGDMRQALNNLQSTFSGFGFINSENVFKVCD 256
>ECU09g1330 [L] KOG0991 Replication factor C subunit RFC2
Length = 309
Score = 72.0 bits (175), Expect = 4e-12
Identities = 57/233 (24%), Positives = 99/233 (42%), Gaps = 25/233 (10%)
Query: 291 LWTTKYAPTDLRQLCGNKGAIQKLKTWLESWSSGKKPSMRAVMLSGPPGIGKTTAAHLVA 350
L KY P++++ + GN+ ++ + +ES M ++ +GPPG GKTT A ++A
Sbjct: 3 LLVNKYQPSEIQDIVGNEATMELVSLMIES------RDMPHLLFTGPPGTGKTTCAKILA 56
Query: 351 KSL---GYDVLEKNASDVRSKGLLNASVKFALDHKSVIGMFKSISDDHYSKNGKRFVIIM 407
+ L +LE NASD R + ++K + FK +II+
Sbjct: 57 RRLLGNKEGLLELNASDERGIDTVRTTIKSFAQRRVKDCEFK--------------IIIL 102
Query: 408 DEXXXXXXXXXXXXXQLAQYCRKTNTPMILICNERNLPKMRPFDHSVLDIPFRRPDAQAV 467
DE ++ + + ILICN P + F R + +
Sbjct: 103 DEADSMTTTAQQAMRRVMEI-HSSECRFILICNVFT-KIFEPIQSRCAILRFDRIEQSVI 160
Query: 468 KARLMTIAMREKFKLDPNVIDRLVSVTRGDMRQIINLLSTVTTTSKSIGSDNI 520
RL I+ E ++ +D +V ++ GDMRQ +N+L + ++ D I
Sbjct: 161 LKRLKEISEGEGIRITAEALDLVVELSDGDMRQSLNILQACINSPGTVDQDYI 213
>YNL290w [L] KOG0990 Replication factor C subunit RFC5
Length = 340
Score = 70.9 bits (172), Expect = 8e-12
Identities = 61/235 (25%), Positives = 104/235 (43%), Gaps = 28/235 (11%)
Query: 292 WTTKYAPTDLRQLCGNKGAIQKLKTWLESWSSGKKPSMRAVMLSGPPGIGKTT-----AA 346
W KY P L ++ G I ++ +++ GK P + + GPPG GKT+ A
Sbjct: 15 WVEKYRPETLDEVYGQNEVITTVRKFVDE---GKLPHL---LFYGPPGTGKTSTIVALAR 68
Query: 347 HLVAKSLGYDVLEKNASDVRSKGLLNASVKFALDHKSVIGMFKSISDDHYSKNGKRFVII 406
+ K+ VLE NASD R ++ +K + + +SK K +II
Sbjct: 69 EIYGKNYSNMVLELNASDDRGIDVVRNQIKDFASTRQI-----------FSKGFK--LII 115
Query: 407 MDEXXXXXXXXXXXXXQLAQYCRKTNTPMILICNERNLPKMRPFDHS-VLDIPFRRPDAQ 465
+DE ++ + K NT ++ N + K+ P S F+ +
Sbjct: 116 LDEADAMTNAAQNALRRVIERYTK-NTRFCVLANYAH--KLTPALLSRCTRFRFQPLPQE 172
Query: 466 AVKARLMTIAMREKFKLDPNVIDRLVSVTRGDMRQIINLLSTVTTTSKSIGSDNI 520
A++ R+ + + EK KL PN L+ ++ GDMR+++N+L + T + D I
Sbjct: 173 AIERRIANVLVHEKLKLSPNAEKALIELSNGDMRRVLNVLQSCKATLDNPDEDEI 227
>ECU01g1180 [L] KOG1968 Replication factor C subunit RFC1 (large subunit)
Length = 383
Score = 70.9 bits (172), Expect = 8e-12
Identities = 62/228 (27%), Positives = 95/228 (41%), Gaps = 34/228 (14%)
Query: 289 SKLWTTKYAPTDLRQLCGNKGAIQKLKTWLESWSSGKKPSMRAVMLSGPPGIGKTTAAHL 348
S LWT KY P +L WL + S R ++L GPPG GKT AH+
Sbjct: 3 SALWTEKYRPRKYTELVFKGDVHHDALRWLRDYPSNG----RILLLCGPPGTGKTALAHV 58
Query: 349 VAKSLGYDVLEKNASDVRSKGLLNASVKFALDHKSVIGMFKSISDDHYSKNGKRFVIIMD 408
++ G +++E NAS D + V I D + NGK+ +I++D
Sbjct: 59 LSSVFGMNLVEFNASS---------------DSEYV----SKILDSGGTINGKKNLILVD 99
Query: 409 EXXXXXXXXXXXXXQLAQYCRKTNTPMILICNERNLPKMRPFDHSVLDIPFRRPDAQAVK 468
E +LA R + P+++ NE L V + +RP ++
Sbjct: 100 E---IDGNPLIEVGRLASSTRLAH-PVVMTSNEVRL-------KDVYTLEIKRPGIDEIR 148
Query: 469 ARLMTIAMREKFKLDPNVIDRLVSVTRGDMRQIINLLSTVTTTSKSIG 516
+ I E ++D +V+ R+V + GD R IIN L + S G
Sbjct: 149 RGIERICREEGIRVDNSVLTRMVEDSGGDFRAIINHLQMCSLVLASSG 196
>At1g77620 [L] KOG1968 Replication factor C subunit RFC1 (large subunit)
Length = 1151
Score = 69.7 bits (169), Expect = 2e-11
Identities = 60/277 (21%), Positives = 108/277 (38%), Gaps = 56/277 (20%)
Query: 280 SSKSTVTEDSKLWTTKYAPTDLRQLCGNKGAIQKLKTWLESW------------------ 321
S+ S+ ++LW KY P ++CGN +++ + WL W
Sbjct: 301 SNDSSGQPCNRLWVDKYQPRSASEVCGNTESVKVMNEWLRQWYERGFQPNKDFLSSDEDK 360
Query: 322 ----------------SSGKKPSMRAVMLS-GPPGIGKTTAAHLVAKSLGYDVLEKNASD 364
SG + S + V+L GP G GK+ A H AK G+ +LE N S+
Sbjct: 361 SQDADYNCSESDSDSEKSGAEDSQKNVLLIVGPAGSGKSAAIHACAKEQGFKILESNTSE 420
Query: 365 VRSKGLLNASVKFALD----HKSVIGMFKSISDD-------------HYSKNGKRF--VI 405
RS ++ AL +S+ +F S +D H +G +I
Sbjct: 421 CRSGTVVRQKFGEALKSYSLSRSLDPLFNSCTDGNGVEDVVEVMPVLHIQNDGANLKPLI 480
Query: 406 IMDEXXXXXXXXXXXXXQLAQYCRKTNTPMILICNERNLPKMRPFDHSVLDIPFRRPDAQ 465
+ ++ + Q K P++L N++N P + ++I F P +
Sbjct: 481 LFEDVDICFAEDRGLVSAIQQIAVKAKGPVVLTANDKN--HGLPDNLERIEIYFSLPSKE 538
Query: 466 AVKARLMTIAMREKFKLDPNVIDRLVSVTRGDMRQII 502
+ L + E+ K++ ++ + + GD+R+ I
Sbjct: 539 ELFNHLSLVCAAEEVKVNHGSLEEMTTFCGGDIRKAI 575
>At1g04730 [DL] KOG1969 DNA replication checkpoint protein CHL12/CTF18
Length = 954
Score = 68.2 bits (165), Expect = 5e-11
Identities = 78/335 (23%), Positives = 134/335 (39%), Gaps = 39/335 (11%)
Query: 327 PSMRAVMLSGPPGIGKTTAAHLVAKSLGYDVLEKNASDVRSKGLLNASVKFALDHKSVIG 386
P + ++L G PG+GKTT AH+ AK GY V+E NASD RS + + + SV
Sbjct: 343 PEQKILLLCGAPGLGKTTLAHIAAKHCGYRVVEINASDERSASAIETRILDVVQMNSVTA 402
Query: 387 MFKS---ISD--DHYSKNGKRFV------IIMDEXXXXXXXXXXXXXQLAQYCRKT---N 432
+ + D D +GK V ++ + ++ R+T +
Sbjct: 403 DSRPKCLVIDEIDGALGDGKGAVDVILKMVLAERKHATGKENVENVKTSSKKDRRTAPLS 462
Query: 433 TPMILICNERNLPKMRPFDHSVLDIPFRRPDAQAVKARLMTIAMREKF-------KLDPN 485
P+I ICN+ P +RP F +P V RL+ + R K+ K
Sbjct: 463 RPVICICNDLYAPALRPLRQIAKVHIFVQPTVSRVVNRLICVNDRLKYICNMEGMKARSF 522
Query: 486 VIDRLVSVTRGDMRQIINLLSTVTTTSKSIGSDNIKSLSDNWEKNVALKIFDITPKLLS- 544
+ L T D+R +N L + ++I +I S K+++ +FDI ++ +
Sbjct: 523 ALSALAEYTECDIRSCLNTLQFLYKKKETINVIDIGSQVVG-RKDMSKSLFDIWKEIFTT 581
Query: 545 -------GGIYTENGAKQFPLYKKMELYFDDFDFTPLMIQENYTSTTPTLLRKGQTHLNA 597
+ +GAK F + D+D I EN L ++
Sbjct: 582 RKMKRERSNDASGSGAKNFDFLHSLVSSRGDYDLIFDGIHENILQ-----LHYHDPVMDK 636
Query: 598 VAAAAESISEGDLVDKKIRSAEQQWSLLPLHAVLS 632
+ + + DL+ + I +Q +PL+ +L+
Sbjct: 637 TISCLDGLGTSDLLHRYIMRTQQ----MPLYVLLN 667
>ECU02g0290 [L] KOG0990 Replication factor C subunit RFC5
Length = 305
Score = 64.7 bits (156), Expect = 6e-10
Identities = 64/247 (25%), Positives = 106/247 (42%), Gaps = 31/247 (12%)
Query: 293 TTKYAPTDLRQLCGNKGAIQKLKTWLESWSSGKKPSMRAVMLSGPPGIGKTTAAHLVAKS 352
T KY P L ++ GN+ + L++ S+G+ P+M + GPPG GKTT+ +A +
Sbjct: 6 TEKYRPGSLLEVVGNREVVSSLQSIS---SAGRIPNM---LFYGPPGTGKTTSIRAIANN 59
Query: 353 LGY-DVLEKNASDVRSKGLLNASVKFALDHKSVIGMFKSISDDHYSKNGKRFVIIMDEXX 411
L VLE NASD R + ++K F S YSK K ++I+DE
Sbjct: 60 LPRTSVLELNASDERGIATVRETIK----------EFAST----YSKTMK--LVILDEAD 103
Query: 412 XXXXXXXXXXXQLAQYCRKTNTPMILICNERNLPKMRPFDHSVLD--IPFRRPDAQAVKA 469
++ + NT LI N +R +L FR +
Sbjct: 104 MMSRDAQNALRRIIEDF-SANTRFCLIANH-----LRKIISPILSRCTKFRFGPIGDTEN 157
Query: 470 RLMTIAMREKFKLDPNVIDRLVSVTRGDMRQIINLLSTVTTTSKSIGSDNIKSLSDNWEK 529
R+ I RE K P I + ++ GDMR+ +N + ++ + + N++ +
Sbjct: 158 RIEEICKRESIKYTPEGIKAVSRISMGDMRKAVNDIQGISASLGQVDESNVRRFNGIAPS 217
Query: 530 NVALKIF 536
+V ++F
Sbjct: 218 SVYEELF 224
>YJR068w [L] KOG0989 Replication factor C subunit RFC4
Length = 353
Score = 62.0 bits (149), Expect = 4e-09
Identities = 59/232 (25%), Positives = 99/232 (42%), Gaps = 19/232 (8%)
Query: 292 WTTKYAPTDLRQLCGNKGAIQKLKTWLESWSSGKKPSMRAVMLSGPPGIGKTTAAHLVAK 351
W KY P +L ++ A+ LK L+S ++ ++ GPPG GKT+ + K
Sbjct: 27 WVEKYRPKNLDEVTAQDHAVTVLKKTLKS------ANLPHMLFYGPPGTGKTSTILALTK 80
Query: 352 SL-GYD-----VLEKNASDVRSKGLLNASVK-FALDHKSVIGMFKSISDDHYSKNGKRFV 404
L G D +LE NASD R ++ VK FA + + ++Y + +
Sbjct: 81 ELYGPDLMKSRILELNASDERGISIVREKVKNFA---RLTVSKPSKHDLENYPCPPYKII 137
Query: 405 IIMDEXXXXXXXXXXXXXQLAQYCRKTNTPMILICNERNLPKMRPFDHSVLDIPFRRPDA 464
I+ + + Y T LICN + P F+ DA
Sbjct: 138 ILDEADSMTADAQSALRRTMETYSGVTR--FCLICNYVT-RIIDPLASRCSKFRFKALDA 194
Query: 465 QAVKARLMTIAMREKFKLDPNVIDRLVSVTRGDMRQIINLLSTVTTTSKSIG 516
RL I+ +E K D V++R++ ++ GD+R+ I LL + + ++ +G
Sbjct: 195 SNAIDRLRFISEQENVKCDDGVLERILDISAGDLRRGITLLQSASKGAQYLG 246
>CE01268 [L] KOG0989 Replication factor C subunit RFC4
Length = 334
Score = 61.2 bits (147), Expect = 6e-09
Identities = 66/239 (27%), Positives = 101/239 (41%), Gaps = 27/239 (11%)
Query: 292 WTTKYAPTDLRQLCGNKGAIQKLKTWLESWSSGKKPSMRAVMLSGPPGIGKTTAA----- 346
WT KY P L + + LK L+ + ++ GPPG GKT+AA
Sbjct: 17 WTEKYRPKTLDDIAYQDEVVTMLKGALQG------RDLPHLLFYGPPGTGKTSAALAFCR 70
Query: 347 HLVAKSLGYD-VLEKNASDVRSKGLLNASVKFALDHKSVIGMFKSISDDHYSKNGKRFVI 405
L K++ +D VL+ NASD R G+ K KS S+ H K +I
Sbjct: 71 QLFPKNIFHDRVLDLNASDER--GIAVVRQKIQSFSKS------SLGHSHREDVLKLKII 122
Query: 406 IMDEXXXXXXXXXXXXXQLAQYCRKTNTPMILICN--ERNLPKMRPFDHSVLDIPFRRPD 463
I+DE ++ + KT T ILICN R +P P F+
Sbjct: 123 ILDEVDAMTREAQAAMRRVIEDFSKT-TRFILICNYVSRLIP---PVVSRCAKFRFKSLP 178
Query: 464 AQAVKARLMTIAMREKFKLDPNVIDRLVSVTRGDMRQIINLLSTVTTTSKSIGSDNIKS 522
A+ RL TI E + + + +++ + GD+R+ + L ++ KS G DN ++
Sbjct: 179 AEIQVQRLRTICDAEGTPMSDDELKQVMEYSEGDLRRAVCTLQSLAPILKS-GDDNARN 236
>7295770 [DL] KOG1969 DNA replication checkpoint protein CHL12/CTF18
Length = 1397
Score = 59.3 bits (142), Expect = 2e-08
Identities = 48/193 (24%), Positives = 76/193 (38%), Gaps = 15/193 (7%)
Query: 326 KPSMRAVMLSGPPGIGKTTAAHLVAKSLGYDVLEKNASDVRSKGLLNASVKFALDHKSVI 385
+P + +L GPPG+GKTT AH +A+ GY+V E NASD RS +++ SV+
Sbjct: 615 RPMQKVALLCGPPGLGKTTLAHTIARHAGYNVREINASDDRSPEAFKLALENGTQMSSVL 674
Query: 386 GMFK---SISDDHYSKNGKRFVIIMDEXXXXXXXXXXXXXQLAQYCRKTNTPMILICNER 442
K I D ++ + + + P+I ICN+
Sbjct: 675 NEDKRPNCIVLDEIDGAPRQSIDYLVKFISDAVYTKVKAKGAKAEHNVLKRPIICICNDV 734
Query: 443 NLPKMRPFDHSVLDIPFRRPDAQAVKARLMTIAMREKFKLDPNVIDRLVSVTRGDMRQII 502
P +RP A L+ IA +E+ K D + L + D+R I
Sbjct: 735 YDPALRPLRQ------------VAFVVTLVKIAFKEQLKTDFGSLIALAEKSGNDVRSCI 782
Query: 503 NLLSTVTTTSKSI 515
+ + S+
Sbjct: 783 SSMQFFNAQKHSL 795
>Hs4506383 [DL] KOG1970 Checkpoint RAD17-RFC complex RAD17/RAD24 component
Length = 670
Score = 58.9 bits (141), Expect = 3e-08
Identities = 71/281 (25%), Positives = 121/281 (42%), Gaps = 47/281 (16%)
Query: 280 SSKSTVTEDSKLWTTKYAPTDLRQLCGNKGAIQKLKTWLESWSSGKKPSMRA--VMLSGP 337
+SK ++E+ W KY P +L +K I++++TWL++ ++P ++++GP
Sbjct: 69 NSKEYLSENEP-WVDKYKPETQHELAVHKKKIEEVETWLKAQVLERQPKQGGSILLITGP 127
Query: 338 PGIGKTTAAHLVAKSLGYDVLE------KNASDVRSKGLLNASVKFAL-DHKSVIGMFKS 390
PG GKTT +++K G V E + KG+ N F + ++S I +FK
Sbjct: 128 PGCGKTTTLKILSKEHGIQVQEWINPVLPDFQKDDFKGMFNTESSFHMFPYQSQIAVFKE 187
Query: 391 -------------ISDDHYSKNGKRFVIIMDEXXXXXXXXXXXXXQLAQYCRKTNTPMIL 437
+ DD + K+ +++ D L +Y R P+I
Sbjct: 188 FLLRATKYNKLQMLGDD--LRTDKKIILVEDLPNQFYRDSHTLHEVLRKYVRIGRCPLIF 245
Query: 438 IC--------NERNL-PKMRPFDHSVLDIPFRRPDAQAVKA----RLMTI-AMREKFKL- 482
I N+R L PK + S+ +I F P A + R++TI A + K+
Sbjct: 246 IISDSLSGDNNQRLLFPKEIQEECSISNISF-NPVAPTIMMKFLNRIVTIEANKNGGKIT 304
Query: 483 --DPNVIDRLVSVTRGDMRQIINLLSTVTTTSKSIGSDNIK 521
D ++ L GD+R IN L S S G +N++
Sbjct: 305 VPDKTSLELLCQGCSGDIRSAINSLQ----FSSSKGENNLR 341
>Hs19718786 [DL] KOG1970 Checkpoint RAD17-RFC complex RAD17/RAD24 component
Length = 681
Score = 58.9 bits (141), Expect = 3e-08
Identities = 71/281 (25%), Positives = 121/281 (42%), Gaps = 47/281 (16%)
Query: 280 SSKSTVTEDSKLWTTKYAPTDLRQLCGNKGAIQKLKTWLESWSSGKKPSMRA--VMLSGP 337
+SK ++E+ W KY P +L +K I++++TWL++ ++P ++++GP
Sbjct: 80 NSKEYLSENEP-WVDKYKPETQHELAVHKKKIEEVETWLKAQVLERQPKQGGSILLITGP 138
Query: 338 PGIGKTTAAHLVAKSLGYDVLE------KNASDVRSKGLLNASVKFAL-DHKSVIGMFKS 390
PG GKTT +++K G V E + KG+ N F + ++S I +FK
Sbjct: 139 PGCGKTTTLKILSKEHGIQVQEWINPVLPDFQKDDFKGMFNTESSFHMFPYQSQIAVFKE 198
Query: 391 -------------ISDDHYSKNGKRFVIIMDEXXXXXXXXXXXXXQLAQYCRKTNTPMIL 437
+ DD + K+ +++ D L +Y R P+I
Sbjct: 199 FLLRATKYNKLQMLGDD--LRTDKKIILVEDLPNQFYRDSHTLHEVLRKYVRIGRCPLIF 256
Query: 438 IC--------NERNL-PKMRPFDHSVLDIPFRRPDAQAVKA----RLMTI-AMREKFKL- 482
I N+R L PK + S+ +I F P A + R++TI A + K+
Sbjct: 257 IISDSLSGDNNQRLLFPKEIQEECSISNISF-NPVAPTIMMKFLNRIVTIEANKNGGKIT 315
Query: 483 --DPNVIDRLVSVTRGDMRQIINLLSTVTTTSKSIGSDNIK 521
D ++ L GD+R IN L S S G +N++
Sbjct: 316 VPDKTSLELLCQGCSGDIRSAINSLQ----FSSSKGENNLR 352
>At1g21690 [L] KOG0989 Replication factor C subunit RFC4
Length = 336
Score = 57.4 bits (137), Expect = 9e-08
Identities = 57/234 (24%), Positives = 94/234 (39%), Gaps = 25/234 (10%)
Query: 285 VTEDSKLWTTKYAPTDLRQLCGNKGAIQKLKTWLESWSSGKKPSMRAVMLSGPPGIGKTT 344
V + S+ W KY P ++ + + ++ L L++ P M + GPPG GKTT
Sbjct: 4 VLQSSQPWVEKYRPKQVKDVAHQEEVVRVLTNTLQTADC---PHM---LFYGPPGTGKTT 57
Query: 345 AAHLVAKSL------GYDVLEKNASDVRSKGLLNASVKFALDHKSVIGMFKSISDDHYSK 398
A +A L VLE NASD R ++ +K D +V ++ +H
Sbjct: 58 TALAIAHQLFGPELYKSRVLELNASDDRGINVVRTKIK---DFAAV-----AVGSNHRQS 109
Query: 399 N---GKRFVIIMDEXXXXXXXXXXXXXQLAQYCRKTNTPMILICNERNLPKMRPFDHSVL 455
+II+DE + + K T ICN + + P
Sbjct: 110 GYPCPSFKIIILDEADSMTEDAQNALRRTMETYSKV-TRFFFICNYIS-RIIEPLASRCA 167
Query: 456 DIPFRRPDAQAVKARLMTIAMREKFKLDPNVIDRLVSVTRGDMRQIINLLSTVT 509
F+ + + R++ I E LD + L S+++GD+R+ I L + T
Sbjct: 168 KFRFKPLSEEVMSNRILHICNEEGLSLDGEALSTLSSISQGDLRRAITYLQSAT 221
>Hs4506491 [L] KOG0989 Replication factor C subunit RFC4
Length = 363
Score = 56.6 bits (135), Expect = 2e-07
Identities = 58/228 (25%), Positives = 90/228 (39%), Gaps = 28/228 (12%)
Query: 292 WTTKYAPTDLRQLCGNKGAIQKLKTWLESWSSGKKPSMRAVMLSGPPGIGKTTAAHLVAK 351
W KY P + ++ + + LK LE + ++ GPPG GKT+ A+
Sbjct: 40 WVEKYRPKCVDEVAFQEEVVAVLKKSLEG------ADLPNLLFYGPPGTGKTSTILAAAR 93
Query: 352 SL------GYDVLEKNASDVRSKGLLNASVKFALDHKSVIGMFKSISDDHYSKNGKRF-- 403
L VLE NASD R ++ VK F ++ +GK
Sbjct: 94 ELFGPELFRLRVLELNASDERGIQVVREKVK----------NFAQLTVSGSRSDGKPCPP 143
Query: 404 --VIIMDEXXXXXXXXXXXXXQLAQYCRKTNTPMILICNERNLPKMRPFDHSVLDIPFRR 461
++I+DE + + KT T LICN + + P F+
Sbjct: 144 FKIVILDEADSMTSAAQAALRRTMEKESKT-TRFCLICNYVSRI-IEPLTSRCSKFRFKP 201
Query: 462 PDAQAVKARLMTIAMREKFKLDPNVIDRLVSVTRGDMRQIINLLSTVT 509
+ + RL+ IA +E K+ I LV V+ GD+R+ I L + T
Sbjct: 202 LSDKIQQQRLLDIAKKENVKISDEGIAYLVKVSEGDLRKAITFLQSAT 249
>Hs6677723 [L] KOG0990 Replication factor C subunit RFC5
Length = 340
Score = 56.2 bits (134), Expect = 2e-07
Identities = 61/254 (24%), Positives = 105/254 (41%), Gaps = 31/254 (12%)
Query: 292 WTTKYAPTDLRQLCGNKGAIQKLKTWLESWSSGKKPSMRAVMLSGPPGIGKTTAAHLVAK 351
W KY P L L ++ + ++ ++ + + ++L GPPG GKT+ AK
Sbjct: 22 WVEKYRPQTLNDLISHQDILSTIQKFIN------EDRLPHLLLYGPPGTGKTSTILACAK 75
Query: 352 SLGYD------VLEKNASDVRSKGLLNASVKFALDHKSVIGMFKSISDDHYSKNGKRF-V 404
L D VLE NASD R ++ + L S +FK K F +
Sbjct: 76 QLYKDKEFGSMVLELNASDDRGIDIIRGPI---LSFASTRTIFK-----------KGFKL 121
Query: 405 IIMDEXXXXXXXXXXXXXQLAQYCRKTNTPMILICNERNLPKMRPFDHS-VLDIPFRRPD 463
+I+DE ++ + + NT LICN L K+ P S F
Sbjct: 122 VILDEADAMTQDAQNALRRVIEKFTE-NTRFCLICNY--LSKIIPALQSRCTRFRFGPLT 178
Query: 464 AQAVKARLMTIAMREKFKLDPNVIDRLVSVTRGDMRQIINLLSTVTTTSKSIGSDNIKSL 523
+ + RL + EK + + + LV+++ GDMR+ +N+L + + + + +
Sbjct: 179 PELMVPRLEHVVEEEKVDISEDGMKALVTLSSGDMRRALNILQSTNMAFGKVTEETVYTC 238
Query: 524 SDNWEKNVALKIFD 537
+ + K+ I D
Sbjct: 239 TGHPLKSDIANILD 252
>ECU02g0680 [L] KOG0989 Replication factor C subunit RFC4
Length = 283
Score = 56.2 bits (134), Expect = 2e-07
Identities = 64/249 (25%), Positives = 100/249 (39%), Gaps = 52/249 (20%)
Query: 291 LWTTKYAPTDLRQLCGNKGAIQKLKTWLESWSSGKKPSMRAVMLSGPPGIGKTTAAHLVA 350
LWT KY P G + LK L + S P++ +L GPPG GKTT AHL+A
Sbjct: 2 LWTEKYRPKSTDAFEGP----EHLKNILRNSSGRGHPNL---LLYGPPGTGKTTFAHLLA 54
Query: 351 KSLGYDVLEKNASDVRSKGLLNASVKFALDHKSVIGMFKSISDDHYSKNGKRFVIIMDEX 410
LE NASD R ++ +K + S GK +I+DE
Sbjct: 55 S----QKLELNASDERGISVIREKIKV-----------------YASTLGKDKTVILDEC 93
Query: 411 XXXXXXXXXXXXQLAQYCRK------TNTPMILICNERNLPKMRPFDHSVLDIPFRRPDA 464
AQ+C + NT I I N + + P ++ + F ++
Sbjct: 94 ENLTSD--------AQHCLRRVIEDSVNTRFIFITNYPS-KIIGPLRSRLVSVKFTPTES 144
Query: 465 QAVKARLMTIAMREKFKLDPNVIDRLVSVTRGDMRQIINLLSTVT-----TTSKSIGSDN 519
+ L I +E D + R++ + D+R+ IN+L V +++G+
Sbjct: 145 KI----LENIGSKEGLGYDKELYHRILKLCGNDLRRAINVLQGVAPLGSFCIEEAVGAVP 200
Query: 520 IKSLSDNWE 528
K++ WE
Sbjct: 201 QKTVDMFWE 209
>SPAC23D3.02 [L] KOG0989 Replication factor C subunit RFC4
Length = 340
Score = 54.3 bits (129), Expect = 8e-07
Identities = 65/267 (24%), Positives = 101/267 (37%), Gaps = 25/267 (9%)
Query: 281 SKSTVTEDSKL--WTTKYAPTDLRQLCGNKGAIQKLKTWLESWSSGKKPSMRAVMLSGPP 338
+K T E K W Y P L Q+ + +Q LK L S P M + G P
Sbjct: 8 NKKTEQEAKKSIPWVELYRPKTLDQVSSQESTVQVLKKTL---LSNNLPHM---LFYGSP 61
Query: 339 GIGKTTAAHLVAKSL------GYDVLEKNASDVRSKGLLNASVKFALDHKSVIGMFKSIS 392
G GKT+ +++ L VLE NASD R ++ VK S +
Sbjct: 62 GTGKTSTILALSRELFGPQLMKSRVLELNASDERGISIIREKVK------SFAKTTVTNK 115
Query: 393 DDHYSKNGKRFVIIMDEXXXXXXXXXXXXXQLAQYCRKTNTPMILICNERNLPKMRPFDH 452
D Y + +I+ + + Y R T LICN + P
Sbjct: 116 VDGYPCPPFKIIILDEADSMTQDAQAALRRTMESYARITR--FCLICNYMTRI-IDPLSS 172
Query: 453 SVLDIPFRRPDAQAVKARLMTIAMREKFKLDPNVIDRLVSVTRGDMRQIINLLSTVTTTS 512
F+ D + + RL IA + ++P V++ LV + GDMR+ I L +
Sbjct: 173 RCSKYRFKPLDNENMVKRLEFIAADQAVSMEPGVVNALVECSGGDMRKAITFLQSAANLH 232
Query: 513 KS--IGSDNIKSLSDNWEKNVALKIFD 537
+ I +++ L+ N+ + D
Sbjct: 233 QGTPITISSVEELAGAVPYNIIRSLLD 259
>At1g77470 [L] KOG0990 Replication factor C subunit RFC5
Length = 369
Score = 51.6 bits (122), Expect = 5e-06
Identities = 51/239 (21%), Positives = 93/239 (38%), Gaps = 24/239 (10%)
Query: 292 WTTKYAPTDLRQLCGNKGAIQKLKTWLESWSSGKKPSMRAVMLSGPPGIGKTTAAHLVAK 351
W KY P L + ++ I + + K P + +L GPPG GKT+ VA+
Sbjct: 41 WVEKYRPQSLDDVAAHRDIIDTIDRLT---NENKLPHL---LLYGPPGTGKTSTILAVAR 94
Query: 352 SLGYD-----VLEKNASDVRSKGLLNASVKFALDHKSVIGMFKSISDDHYSKNGKRFVII 406
L +LE NASD R ++ ++ F S K+ + V++
Sbjct: 95 KLYGPKYRNMILELNASDDRGIDVVRQQIQD----------FASTQSFSLGKSSVKLVLL 144
Query: 407 MDEXXXXXXXXXXXXXQLAQYCRKTNTPMILICNERNLPKMRPFDHSVLDIPFRRPDAQA 466
+ + +Y + T +I + +P ++ F D
Sbjct: 145 DEADAMTKDAQFALRRVIEKYTKSTRFALIGNHVNKIIPALQS---RCTRFRFAPLDGVH 201
Query: 467 VKARLMTIAMREKFKLDPNVIDRLVSVTRGDMRQIINLLSTVTTTSKSIGSDNIKSLSD 525
+ RL + E+ + + LV ++ GDMR+ +N+L + SK I + K +++
Sbjct: 202 MSQRLKHVIEAERLVVSDCGLAALVRLSNGDMRKALNILQSTHMASKEITEEESKQITE 260
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.314 0.130 0.364
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 41,921,253
Number of Sequences: 60738
Number of extensions: 1656187
Number of successful extensions: 4802
Number of sequences better than 1.0e-05: 33
Number of HSP's better than 0.0 without gapping: 12
Number of HSP's successfully gapped in prelim test: 21
Number of HSP's that attempted gapping in prelim test: 4714
Number of HSP's gapped (non-prelim): 49
length of query: 835
length of database: 30,389,216
effective HSP length: 115
effective length of query: 720
effective length of database: 23,404,346
effective search space: 16851129120
effective search space used: 16851129120
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)