ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIV1726 good O KOG2100 Posttranslational modification, protein turnover, chaperones Dipeptidyl aminopeptidase
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIV1726 598068 595453 -872
(872 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YOR219c [O] KOG2100 Dipeptidyl aminopeptidase 635 0.0
YHR028c [O] KOG2100 Dipeptidyl aminopeptidase 370 e-102
SPACUNK4.08 [O] KOG2100 Dipeptidyl aminopeptidase 359 9e-99
Hs18765694 [O] KOG2100 Dipeptidyl aminopeptidase 241 4e-63
Hs18765698 [O] KOG2100 Dipeptidyl aminopeptidase 229 1e-59
Hs18765696 [O] KOG2100 Dipeptidyl aminopeptidase 229 1e-59
Hs16933540 [O] KOG2100 Dipeptidyl aminopeptidase 228 2e-59
7294364 [O] KOG2100 Dipeptidyl aminopeptidase 220 6e-57
7297021 [O] KOG2100 Dipeptidyl aminopeptidase 216 1e-55
Hs22041021 [O] KOG2100 Dipeptidyl aminopeptidase 206 1e-52
CE21196 [O] KOG2100 Dipeptidyl aminopeptidase 191 4e-48
CE21195 [O] KOG2100 Dipeptidyl aminopeptidase 191 4e-48
CE05324 [O] KOG2100 Dipeptidyl aminopeptidase 182 2e-45
At5g24260 [O] KOG2281 Dipeptidyl aminopeptidases/acylaminoacyl-p... 164 4e-40
SPAC14C4.15c [O] KOG2100 Dipeptidyl aminopeptidase 137 9e-32
Hs18450280 [O] KOG2281 Dipeptidyl aminopeptidases/acylaminoacyl-... 130 1e-29
7301225 [O] KOG2281 Dipeptidyl aminopeptidases/acylaminoacyl-pep... 128 3e-29
7293308 [O] KOG2100 Dipeptidyl aminopeptidase 127 1e-28
Hs21040237 [O] KOG2281 Dipeptidyl aminopeptidases/acylaminoacyl-... 124 5e-28
CE28837 [O] KOG2281 Dipeptidyl aminopeptidases/acylaminoacyl-pep... 114 9e-25
CE17153 [O] KOG2281 Dipeptidyl aminopeptidases/acylaminoacyl-pep... 114 9e-25
Hs18450278 [O] KOG2281 Dipeptidyl aminopeptidases/acylaminoacyl-... 61 7e-09
7289544 [O] KOG2100 Dipeptidyl aminopeptidase 56 2e-07
CE01231 [O] KOG2100 Dipeptidyl aminopeptidase 51 9e-06
>YOR219c [O] KOG2100 Dipeptidyl aminopeptidase
Length = 931
Score = 635 bits (1637), Expect = 0.0
Identities = 320/772 (41%), Positives = 477/772 (61%), Gaps = 20/772 (2%)
Query: 117 INKRGFTIDAFLNGTFVSREDTFKFIAPPAIEYIPKEKDSGLYLTMEKNSQKDDIIVAKR 176
+ KR F+I+ LNG F EDTF FI PP + ++ D GLY T ++ + I AK+
Sbjct: 160 LGKRSFSIENVLNGDFAIPEDTFHFIDPPQ-RLLGQDSDPGLYFTTKEIDGHTNFI-AKQ 217
Query: 177 LNDKDFRKLISPLQFTFNEHKYSLESISIDYSLDYAILGSNVIKEYRHSSSGLYWLYNLK 236
L D+ F + +F + ++++ ++ I+Y LD I G+N+ E+RHSS G YW+ +L
Sbjct: 218 LFDETFEVNLGGNRFLYEGVEFTVSTVQINYKLDKLIFGTNLESEFRHSSKGFYWIKDLN 277
Query: 237 TSVLTPVKGKDSKSPH-----PRLSYCHFSPSYRYIYFVEDNDLHVQSLDDQGDIYRITS 291
T + P+ + + +LSY HFSP+Y YIYFV +N+L +Q ++ G ++T
Sbjct: 278 TGNIEPILPPEKSDDNYELGLSKLSYAHFSPAYNYIYFVYENNLFLQQVNS-GVAKKVTE 336
Query: 292 DGSNYVLNGRTDWVYEEELLXXXXXXXXXXXXSKLAFSRIDDAKVSNYNYQTFINGKQTP 351
DGS + N + DW+YEEE+L SK F+R +D V + + N +
Sbjct: 337 DGSKDIFNAKPDWIYEEEVLASDQAIWWAPDDSKAVFARFNDTSVDDIRLNRYTNMNEAY 396
Query: 352 TLRS-MKYPLPGASNPVICLFLYDLTNNSLNAIKETTEEEGILLYYAKWVDNNNLLFKVS 410
+ +KYP PG NP LFL +L N + +I +++ IL Y KW+ + F+++
Sbjct: 397 LSDTKIKYPKPGFQNPQFDLFLVNLQNGIIYSINTGGQKDSIL-YNGKWISPDTFRFEIT 455
Query: 411 DRESKILDTMIFNSENNQTKRLLTRDANTYNGWIEKCKEIIVVRRKGQ--DINTGFLDIL 468
DR SKILD +++ ++Q + ++N +NGWIEK K+I+ + K + ++ G++DI
Sbjct: 456 DRNSKILDVKVYDIPSSQMLTVRNTNSNLFNGWIEKTKDILSIPPKPELKRMDYGYIDIH 515
Query: 469 PDKNGYHHIFHFASSEDTNPRQITEGSWEV--KEILGVEGESEIVYFQSNLFHPMGLQLH 526
D G+ H+F++ + P Q+T+G+WEV I+G E E++ ++F +N M L+
Sbjct: 516 ADSRGFSHLFYYPTVFAKEPIQLTKGNWEVTGNGIVGYEYETDTIFFTANEIGVMSQHLY 575
Query: 527 TASLKDNSATLNLQQ----TEVLEYSKFTLSTSCKFAIKQYLGPDVPYTYAGDLWQLLNA 582
+ SL D++ Q ++ ++ F LS+S ++AI + LGPD P AG L ++LN
Sbjct: 576 SISLTDSTTQNTFQSLQNPSDKYDFYDFELSSSARYAISKKLGPDTPIKVAGPLTRVLNV 635
Query: 583 SE-DDHSKILLTKNEHIEEAIQMYDYPVTDYKEITLEDYTEINYVEIKPKTFEPEKKYPL 641
+E D S + LTK+E +E I+ YD P+T YK + L+D EINY+EIKP P+KKYP+
Sbjct: 636 AEIHDDSILQLTKDEKFKEKIKNYDLPITSYKTMVLDDGVEINYIEIKPANLNPKKKYPI 695
Query: 642 LVYVYGGPGSETFNTKFXXXXXXXXXXXXXXXVLKIEPRGTGGKGWNFKSWANRNIGFWE 701
LV +YGGPGS+TF TK VL+IEPRGTGGKGW+F+SWA +G+WE
Sbjct: 696 LVNIYGGPGSQTFTTKSSLAFEQAVVSGLDVIVLQIEPRGTGGKGWSFRSWAREKLGYWE 755
Query: 702 PRDIINVTKKYIETQKDVIAQDKVAIWGWSYGGFTTLKTLEFDKGSVFKYGVSVAPVTDW 761
PRDI VTKK+I+ I + K+AIWGWSYGGFT+LKT+E D G FKY ++VAPVT+W
Sbjct: 756 PRDITEVTKKFIQRNSQHIDESKIAIWGWSYGGFTSLKTVELDNGDTFKYAMAVAPVTNW 815
Query: 762 KYYDSVYSERYLGSPLSS-DAYDKNAKIKDYDSFKFTKRFLLMHGTADDNVHIQNTYELI 820
YDSVY+ERY+ P + + Y + + I+++ SF+ KR ++HGT DDNVHIQNT+ L+
Sbjct: 816 TLYDSVYTERYMNQPSENHEGYFEVSTIQNFKSFESLKRLFIVHGTFDDNVHIQNTFRLV 875
Query: 821 DNFNLHSVRNYDMHIFPDSDHSIYFHNAQRMVYEKIYFWIKDAFLGRLDSLE 872
D NL + NYDMHIFPDSDHSI +HNAQR+V++K+Y+W++DAF R D+ E
Sbjct: 876 DQLNLLGLTNYDMHIFPDSDHSIRYHNAQRIVFQKLYYWLRDAFAERFDNTE 927
>YHR028c [O] KOG2100 Dipeptidyl aminopeptidase
Length = 818
Score = 370 bits (949), Expect = e-102
Identities = 233/761 (30%), Positives = 390/761 (50%), Gaps = 46/761 (6%)
Query: 129 NGTFVSREDTFKFIAPPAIEYIPKEKDSGLYLTMEKNSQKDDIIVAKRLNDKDFRK-LIS 187
N TF + ++I+ IE D GLY+T +D V K + D + L+
Sbjct: 79 NNTFQPKYHELQWISDNKIE----SNDLGLYVTF-----MNDSYVVKSVYDDSYNSVLLE 129
Query: 188 PLQFTFNEHKYSLESISIDYSLDYAILGSNVIKEYRHSSSGLYWLYNLKTSVLTPVKGKD 247
F N ++ESI+ L ++ +N ++ +RHS+ G Y++Y+ +S + +
Sbjct: 130 GKTFIHNGQNLTVESITASPDLKRLLIRTNSVQNWRHSTFGSYFVYDKSSSSFEEIGNE- 188
Query: 248 SKSPHPRLSYCHFSPSYRYIYFVEDNDLHVQSLDDQGDIYRITSDGSNYVLNGRTDWVYE 307
++ +SP+ I +V+DN++++ S + I +T+DGS+++ NG+ DWVYE
Sbjct: 189 -------VALAIWSPNSNDIAYVQDNNIYIYSAISKKTIRAVTNDGSSFLFNGKPDWVYE 241
Query: 308 EELLXXXXXXXXXXXXSKLAFSRIDDAKVSNYNYQTFINGKQT--PTLRSMKYPLPGASN 365
EE+ LAF +ID+++V + ++ ++ P +RS+KYP G N
Sbjct: 242 EEVFEDDKAAWWSPTGDYLAFLKIDESEVGEFIIPYYVQDEKDIYPEMRSIKYPKSGTPN 301
Query: 366 PVICLFLYDLTNNSL--NAIKETTEEEGILLYYAKWVDNNNLLFKVSDRESKILDTMIFN 423
P L++Y + + + I ++ +L+ WV N N+L K +DR S IL + +
Sbjct: 302 PHAELWVYSMKDGTSFHPRISGNKKDGSLLITEVTWVGNGNVLVKTTDRSSDILTVFLID 361
Query: 424 SENNQTKRLLTRDANTYNGWIEKCKEIIVV--RRKGQDINTGFLDILPDKNGYHHIFHFA 481
+ + + R+ ++ GW E + + + G++DILP GY+H+ +F
Sbjct: 362 TIAKTSN--VVRNESSNGGWWEITHNTLFIPANETFDRPHNGYVDILPI-GGYNHLAYFE 418
Query: 482 SSEDTNPRQITEGSWEVKE-ILGVEGESEIVYFQSNLFHPMGLQLHTASLKDNSATLNLQ 540
+S ++ + +TEG WEV L + +YF S ++ L+ + + +
Sbjct: 419 NSNSSHYKTLTEGKWEVVNGPLAFDSMENRLYFISTRKSSTERHVYYIDLRSPNEIIEVT 478
Query: 541 QTEVLEYSKFTLSTSCKFAIKQYLGPDVPYTYAGDLWQLLNASEDDHSKIL------LTK 594
T + S+ +F + Y GP VPY D + A + D +L L K
Sbjct: 479 DTSEDGVYDVSFSSGRRFGLLTYKGPKVPYQKIVD-FHSRKAEKCDKGNVLGKSLYHLEK 537
Query: 595 NEHIEEAIQMYDYPVTDYKEITL--EDYTE---INYVEIKPKTFEP--EKKYPLLVYVYG 647
NE + + ++ Y P ++E+ L +++ + +N EI P F+ YP+ + YG
Sbjct: 538 NEVLTKILEDYAVPRKSFRELNLGKDEFGKDILVNSYEILPNDFDETLSDHYPVFFFAYG 597
Query: 648 GPGSETFNTKFXXXXXXXXXXXXXXXVLKIEPRGTGGKGWNFKSWANRNIGFWEPRDIIN 707
GP S+ F V+ ++ RGTG KG +F+S +G +E RD I+
Sbjct: 598 GPNSQQVVKTFSVGFNEVVASQLNAIVVVVDGRGTGFKGQDFRSLVRDRLGDYEARDQIS 657
Query: 708 VTKKYIETQKDVIAQDKVAIWGWSYGGFTTLKTLEFDKGSVFKYGVSVAPVTDWKYYDSV 767
Y + K++++GWSYGG+ TLKTLE D G FKYG+SVAPVTDW++YDSV
Sbjct: 658 AASLY--GSLTFVDPQKISLFGWSYGGYLTLKTLEKDGGRHFKYGMSVAPVTDWRFYDSV 715
Query: 768 YSERYLGSPLSS-DAYDKNAKIKDYDSFKFTKRFLLMHGTADDNVHIQNTYELIDNFNLH 826
Y+ERY+ +P + D Y +++ + + + RFLLMHGT DDNVH QN+ + +D +L+
Sbjct: 716 YTERYMHTPQENFDGYVESS-VHNVTALAQANRFLLMHGTGDDNVHFQNSLKFLDLLDLN 774
Query: 827 SVRNYDMHIFPDSDHSIYFHNAQRMVYEKIYFWIKDAFLGR 867
V NYD+H+FPDSDHSI +HNA +V++K+ W K AF G+
Sbjct: 775 GVENYDVHVFPDSDHSIRYHNANVIVFDKLLDWAKRAFDGQ 815
>SPACUNK4.08 [O] KOG2100 Dipeptidyl aminopeptidase
Length = 793
Score = 359 bits (922), Expect = 9e-99
Identities = 227/704 (32%), Positives = 364/704 (51%), Gaps = 40/704 (5%)
Query: 183 RKLISPLQFTFNEHKYSLESISIDYSLDYAILGSNVIKEYRHSSSGLYWLYNLKTSVLTP 242
+ L S +N + +S SI + Y ++ N + +RHSS Y+LYN +T +
Sbjct: 102 KTLFSVSDLVYNGIQLDYDSYSISFDAKYVLVSVNKSQRWRHSSFAQYYLYNTETKDVNM 161
Query: 243 VKGKDSKSPHPRLSYCHFSPSYRYIYFVEDNDLHVQSLDDQGDIYRITSDGSNYVLNGRT 302
+ G+D++ H +S +SP+ + FV +NDL+V+ D G++ R+T DG+ V NG T
Sbjct: 162 L-GQDNE--HWTISLAEWSPTGHQLSFVYNNDLYVRKND--GNVQRLTYDGTVDVFNGLT 216
Query: 303 DWVYEEELLXXXXXXXXXXXXSKLAFSRIDDAKVSNYNYQTFINGKQTPTL--------R 354
DW+YEEE+L K+AF +++++++ Y+Y + + P+L
Sbjct: 217 DWIYEEEVLSSPSTIWWSPDSDKIAFLKLNESEIPTYHYPLY-TAELDPSLPEFDYNKDM 275
Query: 355 SMKYPLPGASNPVICLFLYDLTNNSLNAIKETTEEEGI--LLYYAKWVDNNNLLFKVSDR 412
++KYP PG NP + LF+ DL +N+ + E ++ WV+ +++L + ++R
Sbjct: 276 AIKYPKPGNPNPSVSLFVADLNSNASSNFSLWHNEPLAEPVVQNVLWVNTSSVLVQFTNR 335
Query: 413 ESKILDTMIFNSENNQTKRLLTRDANTYNGWIEKCKEIIVVRRKG----QDINTGFLDIL 468
S + + ++E + T GW E + + ++ + G+ DIL
Sbjct: 336 NSTCITARLLDTELKSIHTVKTECLE--EGWYEVQQSAKMFPLNNSLVWENWSDGYFDIL 393
Query: 469 PDKNGYHHIFHFASSEDTNPRQITEGSWEVKE-ILGVEGESEIVYFQSNLFHPMGLQLHT 527
+ Y+H+ F ++P +T G+W+V + + ++G+ VYF + L L+
Sbjct: 394 A-LDDYNHLA-FIPFNGSSPIYLTSGAWDVTDGPIHIDGDFGNVYFLATLKDSTERHLYY 451
Query: 528 ASLKDNSATLNLQQTEVLEYSKFTLSTSCKFAIKQYLGPDVPYTYAGDLWQLLNASEDDH 587
SL E Y + S F + Y GPDVP WQ L +++D
Sbjct: 452 VSLDTLEIYGITDNGEDEGYYSTSFSPFGDFYVLNYHGPDVP-------WQELRSTKDKD 504
Query: 588 SKILLTKNEHIEEAIQMYDYPVTDYKEITLEDYTEINYVEIKPKTFEPEKKYPLLVYVYG 647
+ L N +++ + P +Y ++T D T N++E +P+ F+ KKYP+L + YG
Sbjct: 505 YCLSLETNSRLKQQLSSITLPSVEYGKLTFND-TTFNFMERRPRNFDVNKKYPVLFFAYG 563
Query: 648 GPGSETFNTKFXXXXXXXXXXX--XXXXVLKIEPRGTGGKGWNFKSWANRNIGFWEPRDI 705
GPGS+ F V+ ++ RGTG G F+ +R++G WE D
Sbjct: 564 GPGSQQVAKLFRVDFQAYLASHPDFEFIVVTLDGRGTGFNGNAFRYSVSRHLGEWESYDQ 623
Query: 706 INVTKKYIETQKDVIAQDKVAIWGWSYGGFTTLKTLEFDKGSVFKYGVSVAPVTDWKYYD 765
K + + + ++ V IWGWSYGG+ TLKTLE VF YG++VAPVTDW+ YD
Sbjct: 624 GQAGKFWADLP--FVDENHVGIWGWSYGGYLTLKTLETQ--DVFSYGMAVAPVTDWRLYD 679
Query: 766 SVYSERYLGSPLSSDAYDKNAKIKDYDSFKFTKRFLLMHGTADDNVHIQNTYELIDNFNL 825
SVY+ERY+ P + KN++I DY+ FK KRF + HGT DDNVH Q++ L+D NL
Sbjct: 680 SVYTERYMDLPQYNKEGYKNSQIHDYEKFKQLKRFFVAHGTGDDNVHFQHSMHLMDGLNL 739
Query: 826 HSVRNYDMHIFPDSDHSIYFHNAQRMVYEKIYFWIKDAFLGRLD 869
+ NYDM +FPDS HSI +HNA +Y ++ WI DA LGR+D
Sbjct: 740 ANCYNYDMAVFPDSAHSISYHNASLSIYHRLSEWIGDA-LGRID 782
>Hs18765694 [O] KOG2100 Dipeptidyl aminopeptidase
Length = 766
Score = 241 bits (615), Expect = 4e-63
Identities = 213/788 (27%), Positives = 365/788 (46%), Gaps = 77/788 (9%)
Query: 104 IYLGTATDDTTYLINKRGFTIDAFLNGTFVSREDTFKFIAPPAIEYIPKEKDSGLYLTME 163
+ L TDD T +++ +T+ +L T+ + + ++I+ EY+ K++++ L E
Sbjct: 26 VLLNKGTDDAT-ADSRKTYTLTDYLKNTYRLKLYSLRWISDH--EYLYKQENNILVFNAE 82
Query: 164 KNSQKDDIIVAKRLNDKDFRKLISPLQFTFNEHKYSLESISIDYSLDYAILGSNVIKEYR 223
N F + TF+E +S+ SI + +L N +K++R
Sbjct: 83 YG------------NSSVFLE-----NSTFDEFGHSINDYSISPDGQFILLEYNYVKQWR 125
Query: 224 HSSSGLYWLYNL-KTSVLTPVKGKDSKSPHPRLSYCHFSPSYRYIYFVEDNDLHVQSLDD 282
HS + Y +Y+L K ++T + + P+ + +SP + +V +ND++V+ ++
Sbjct: 126 HSYTASYDIYDLNKRQLIT-----EERIPN-NTQWVTWSPVGHKLAYVWNNDIYVK-IEP 178
Query: 283 QGDIYRITSDGSNYVL-NGRTDWVYEEELLXXXXXXXXXXXXSKLAFSRIDDAKVSNYNY 341
YRIT G ++ NG TDWVYEEE+ + LA+++ +D +V Y
Sbjct: 179 NLPSYRITWTGKEDIIYNGITDWVYEEEVFSAYSALWWSPNGTFLAYAQFNDTEVPLIEY 238
Query: 342 QTFINGK-QTPTLRSMKYPLPGASNPVICLFLYDLTNNSLNAIKETTEEE---------- 390
+ + Q P + YP GA NP + F+ + +SL+++ T +
Sbjct: 239 SFYSDESLQYPKTVRVPYPKAGAVNPTVKFFV--VNTDSLSSVTNATSIQITAPASMLIG 296
Query: 391 GILLYYAKWVDNNNLLFKVSDR--ESKILDTMIFNSENNQTKRLLTRD--ANTYNGWIEK 446
L W + + R ++D ++ + + L+ R + GW+ +
Sbjct: 297 DHYLCDVTWATQERISLQWLRRIQNYSVMDICDYDESSGRWNCLVARQHIEMSTTGWVGR 356
Query: 447 CKEIIVVRRKGQDINTGFLDILPDKNGYHHIFHFASSEDTNPRQITEGSWEVKEILGVEG 506
+ D N+ F I+ ++ GY HI +F + + IT+G+WEV +G+E
Sbjct: 357 FRPS--EPHFTLDGNS-FYKIISNEEGYRHICYF-QIDKKDCTFITKGTWEV---IGIEA 409
Query: 507 -ESEIVYFQSNLFH--PMGLQLHTASLKDNSATLNLQ---QTEVLEYSKFTLSTSCKFAI 560
S+ +Y+ SN + P G L+ L D + L E +Y + S K+
Sbjct: 410 LTSDYLYYISNEYKGMPGGRNLYKIQLSDYTKVTCLSCELNPERCQYYSVSFSKEAKYYQ 469
Query: 561 KQYLGPDVP-YTYAGDLWQLLNASEDDHSKILLTKNEHIEEAIQMYDYPVTDYKEITLED 619
+ GP +P YT L++S +D +L N +++ +Q P I L +
Sbjct: 470 LRCSGPGLPLYT--------LHSSVNDKGLRVLEDNSALDKMLQNVQMPSKKLDFIILNE 521
Query: 620 YTEINYVEIKPKTFEPEKKYPLLVYVYGGPGSETFNTKFXXXXXXXXXXXXXXXVLKIEP 679
T+ Y I P F+ KKYPLL+ VY GP S+ +T F V +
Sbjct: 522 -TKFWYQMILPPHFDKSKKYPLLLDVYAGPCSQKADTVFRLNWATYLASTENIIVASFDG 580
Query: 680 RGTGGKGWNFKSWANRNIGFWEPRDIINVTKKYIETQKDVIAQDKVAIWGWSYGGFTTLK 739
RG+G +G NR +G +E D I +++ ++ + ++AIWGWSYGG+ T
Sbjct: 581 RGSGYQGDKIMHAINRRLGTFEVEDQIEAARQF--SKMGFVDNKRIAIWGWSYGGYVTSM 638
Query: 740 TLEFDKGSVFKYGVSVAPVTDWKYYDSVYSERYLGSPLSSDAYD--KNAKIKD-YDSFKF 796
L G VFK G++VAPV+ W+YYDSVY+ERY+G P D D +N+ + ++FK
Sbjct: 639 VLGSGSG-VFKCGIAVAPVSRWEYYDSVYTERYMGLPTPEDNLDHYRNSTVMSRAENFKQ 697
Query: 797 TKRFLLMHGTADDNVHIQNTYELIDNFNLHSVRNYDMHIFPDSDHSIYFHNAQRMVYEKI 856
+ +LL+HGTADDNVH Q + + I + ++ + D DH I A + +Y +
Sbjct: 698 VE-YLLIHGTADDNVHFQQSAQ-ISKALVDVGVDFQAMWYTDEDHGIASSTAHQHIYTHM 755
Query: 857 YFWIKDAF 864
+IK F
Sbjct: 756 SHFIKQCF 763
>Hs18765698 [O] KOG2100 Dipeptidyl aminopeptidase
Length = 865
Score = 229 bits (584), Expect = 1e-59
Identities = 194/789 (24%), Positives = 351/789 (43%), Gaps = 71/789 (8%)
Query: 98 NIFFQGIYLGTATDDTTYLINKRGFTIDAFLNGTFVSREDTFKFIAPPAIEYIPKEKDSG 157
++ + L T +D + L K+ T++ + F + K+I+ E+I +E+
Sbjct: 108 SLIVTSVILLTPAEDNS-LSQKKKVTVEDLFSEDFKIHDPEAKWISDT--EFIYREQKGT 164
Query: 158 LYLTMEKNSQKDDIIVAKRLNDKDFRKLISPLQFTFNEHKYSLESISIDYSLD--YAILG 215
+ L + + +I K++ SL +I + S D YA+
Sbjct: 165 VRLWNVETNTSTVLIEGKKIE--------------------SLRAIRYEISPDREYALFS 204
Query: 216 SNVIKEYRHSSSGLYWLYNLKTSVLTPVKGKDSKSPHP------RLSYCHFSPSYRYIYF 269
NV Y+HS +G Y VL+ + D +S P +L Y + P + + F
Sbjct: 205 YNVEPIYQHSYTGYY--------VLSKIPHGDPQSLDPPEVSNAKLQYAGWGPKGQQLIF 256
Query: 270 VEDNDLHVQSLDDQGDIYRITSDGSNYVLNGRTDWVYEEELLXXXXXXXXXXXXSKLAFS 329
+ +N+++ + + I +++ + NG +DW+YEEE+L ++LA++
Sbjct: 257 IFENNIYYCAHVGKQAIRVVSTGKEGVIYNGLSDWLYEEEILKTHIAHWWSPDGTRLAYA 316
Query: 330 RIDDAKVSNYNYQTFINGKQTPTLRSMKYPLPGASNPVICLFLYDLTNNSLNAIKETTEE 389
I+D++V T+ G PT++ YP G+ NP I L + L + + ++
Sbjct: 317 AINDSRVPIMELPTY-TGSIYPTVKPYHYPKAGSENPSISLHVIGLNGPTHDLEMMPPDD 375
Query: 390 EGILLYY---AKWVDNNNLLFKVSDRESKILDTMIFNSENNQTKRLLTRDANTYNGWIEK 446
+ YY KW + + +R + + ++ + + + W+ +
Sbjct: 376 PRMREYYITMVKWATSTKVAVTWLNRAQNVSILTLCDATTGVCTK---KHEDESEAWLHR 432
Query: 447 CKEIIVVRRKGQDINTGFLDILPD--KNGYHHIFHFAS---SEDTNPRQITEGSWEVKEI 501
E V + G+ F+ +P + ++HI +S S + N + IT G W+V +I
Sbjct: 433 QNEEPVFSKDGRKFF--FIRAIPQGGRGKFYHITVSSSQPNSSNDNIQSITSGDWDVTKI 490
Query: 502 LGVEGESEIVYFQSNLFHPMGLQLHTASLKDN--SATLNLQQTEVLEYSKFTLSTSCKFA 559
L + + +YF S P QL++A+ N L+ E Y + S S F
Sbjct: 491 LAYDEKGNKIYFLSTEDLPRRRQLYSANTVGNFNRQCLSCDLVENCTYFSASFSHSMDFF 550
Query: 560 IKQYLGPDVPYTYAGDLWQLLNASEDDHSKILLTKNEHIEEAIQMYDYPVTDYKEITLED 619
+ + GP VP ++ + D L NEH+++AI P +Y++I ++D
Sbjct: 551 LLKCEGPGVPMV-------TVHNTTDKKKMFDLETNEHVKKAINDRQMPKVEYRDIEIDD 603
Query: 620 YTEINYVEIKPKTFEPEKKYPLLVYVYGGPGSETFNTKFXXXXXXXXXXXXXXXVLKIEP 679
Y + +KP TF YPLL+ V G PGS++ KF V+K +
Sbjct: 604 YNLPMQI-LKPATFTDTTHYPLLLVVDGTPGSQSVAEKFEVSWETVMVSSHGAVVVKCDG 662
Query: 680 RGTGGKGWNFKSWANRNIGFWEPRDIINVTKKYIETQKDVIAQDKVAIWGWSYGGFTTLK 739
RG+G +G R +G E +D + + ++ Q I + +VA++G YGG+ +
Sbjct: 663 RGSGFQGTKLLHEVRRRLGLLEEKDQMEAVRTMLKEQ--YIDRTRVAVFGKDYGGYLSTY 720
Query: 740 TLEF---DKGSVFKYGVSVAPVTDWKYYDSVYSERYLG-SPLSSDAYDKNAKIKDYDSFK 795
L ++G F G +++P+TD+K Y S +SERYLG L + AY+ K+ S
Sbjct: 721 ILPAKGENQGQTFTCGSALSPITDFKLYASAFSERYLGLHGLDNRAYEM-TKVAHRVSAL 779
Query: 796 FTKRFLLMHGTADDNVHIQNTYELIDNFNLHSVRNYDMHIFPDSDHSIYFHNAQRMVYEK 855
++FL++H TAD+ +H Q+T ELI + NY + I+PD H + ++ +Y
Sbjct: 780 EEQQFLIIHPTADEKIHFQHTAELITQL-IRGKANYSLQIYPDESHYFTSSSLKQHLYRS 838
Query: 856 IYFWIKDAF 864
I + + F
Sbjct: 839 IINFFVECF 847
>Hs18765696 [O] KOG2100 Dipeptidyl aminopeptidase
Length = 803
Score = 229 bits (584), Expect = 1e-59
Identities = 194/789 (24%), Positives = 351/789 (43%), Gaps = 71/789 (8%)
Query: 98 NIFFQGIYLGTATDDTTYLINKRGFTIDAFLNGTFVSREDTFKFIAPPAIEYIPKEKDSG 157
++ + L T +D + L K+ T++ + F + K+I+ E+I +E+
Sbjct: 46 SLIVTSVILLTPAEDNS-LSQKKKVTVEDLFSEDFKIHDPEAKWISDT--EFIYREQKGT 102
Query: 158 LYLTMEKNSQKDDIIVAKRLNDKDFRKLISPLQFTFNEHKYSLESISIDYSLD--YAILG 215
+ L + + +I K++ SL +I + S D YA+
Sbjct: 103 VRLWNVETNTSTVLIEGKKIE--------------------SLRAIRYEISPDREYALFS 142
Query: 216 SNVIKEYRHSSSGLYWLYNLKTSVLTPVKGKDSKSPHP------RLSYCHFSPSYRYIYF 269
NV Y+HS +G Y VL+ + D +S P +L Y + P + + F
Sbjct: 143 YNVEPIYQHSYTGYY--------VLSKIPHGDPQSLDPPEVSNAKLQYAGWGPKGQQLIF 194
Query: 270 VEDNDLHVQSLDDQGDIYRITSDGSNYVLNGRTDWVYEEELLXXXXXXXXXXXXSKLAFS 329
+ +N+++ + + I +++ + NG +DW+YEEE+L ++LA++
Sbjct: 195 IFENNIYYCAHVGKQAIRVVSTGKEGVIYNGLSDWLYEEEILKTHIAHWWSPDGTRLAYA 254
Query: 330 RIDDAKVSNYNYQTFINGKQTPTLRSMKYPLPGASNPVICLFLYDLTNNSLNAIKETTEE 389
I+D++V T+ G PT++ YP G+ NP I L + L + + ++
Sbjct: 255 AINDSRVPIMELPTY-TGSIYPTVKPYHYPKAGSENPSISLHVIGLNGPTHDLEMMPPDD 313
Query: 390 EGILLYY---AKWVDNNNLLFKVSDRESKILDTMIFNSENNQTKRLLTRDANTYNGWIEK 446
+ YY KW + + +R + + ++ + + + W+ +
Sbjct: 314 PRMREYYITMVKWATSTKVAVTWLNRAQNVSILTLCDATTGVCTK---KHEDESEAWLHR 370
Query: 447 CKEIIVVRRKGQDINTGFLDILPD--KNGYHHIFHFAS---SEDTNPRQITEGSWEVKEI 501
E V + G+ F+ +P + ++HI +S S + N + IT G W+V +I
Sbjct: 371 QNEEPVFSKDGRKFF--FIRAIPQGGRGKFYHITVSSSQPNSSNDNIQSITSGDWDVTKI 428
Query: 502 LGVEGESEIVYFQSNLFHPMGLQLHTASLKDN--SATLNLQQTEVLEYSKFTLSTSCKFA 559
L + + +YF S P QL++A+ N L+ E Y + S S F
Sbjct: 429 LAYDEKGNKIYFLSTEDLPRRRQLYSANTVGNFNRQCLSCDLVENCTYFSASFSHSMDFF 488
Query: 560 IKQYLGPDVPYTYAGDLWQLLNASEDDHSKILLTKNEHIEEAIQMYDYPVTDYKEITLED 619
+ + GP VP ++ + D L NEH+++AI P +Y++I ++D
Sbjct: 489 LLKCEGPGVPMV-------TVHNTTDKKKMFDLETNEHVKKAINDRQMPKVEYRDIEIDD 541
Query: 620 YTEINYVEIKPKTFEPEKKYPLLVYVYGGPGSETFNTKFXXXXXXXXXXXXXXXVLKIEP 679
Y + +KP TF YPLL+ V G PGS++ KF V+K +
Sbjct: 542 YNLPMQI-LKPATFTDTTHYPLLLVVDGTPGSQSVAEKFEVSWETVMVSSHGAVVVKCDG 600
Query: 680 RGTGGKGWNFKSWANRNIGFWEPRDIINVTKKYIETQKDVIAQDKVAIWGWSYGGFTTLK 739
RG+G +G R +G E +D + + ++ Q I + +VA++G YGG+ +
Sbjct: 601 RGSGFQGTKLLHEVRRRLGLLEEKDQMEAVRTMLKEQ--YIDRTRVAVFGKDYGGYLSTY 658
Query: 740 TLEF---DKGSVFKYGVSVAPVTDWKYYDSVYSERYLG-SPLSSDAYDKNAKIKDYDSFK 795
L ++G F G +++P+TD+K Y S +SERYLG L + AY+ K+ S
Sbjct: 659 ILPAKGENQGQTFTCGSALSPITDFKLYASAFSERYLGLHGLDNRAYEM-TKVAHRVSAL 717
Query: 796 FTKRFLLMHGTADDNVHIQNTYELIDNFNLHSVRNYDMHIFPDSDHSIYFHNAQRMVYEK 855
++FL++H TAD+ +H Q+T ELI + NY + I+PD H + ++ +Y
Sbjct: 718 EEQQFLIIHPTADEKIHFQHTAELITQL-IRGKANYSLQIYPDESHYFTSSSLKQHLYRS 776
Query: 856 IYFWIKDAF 864
I + + F
Sbjct: 777 IINFFVECF 785
>Hs16933540 [O] KOG2100 Dipeptidyl aminopeptidase
Length = 760
Score = 228 bits (582), Expect = 2e-59
Identities = 195/731 (26%), Positives = 321/731 (43%), Gaps = 88/731 (12%)
Query: 120 RGFTIDAFLNGTFVSREDTFKFIAPPAI---EYIPKEKDSGLYLTMEKNSQKDDIIVAKR 176
R T+ LNGTF ++K P I EY+ + D+ + L + Q I+ +
Sbjct: 40 RALTLKDILNGTF-----SYKTFFPNWISGQEYLHQSADNNIVLYNIETGQSYTILSNRT 94
Query: 177 LNDKDFRKLISPLQFTFNEHKYSLESISIDYSLDYAILGSNVIKEYRHSSSGLYWLYNLK 236
+ + N Y L + L S+ K +R+S + Y++Y+L
Sbjct: 95 MK-------------SVNASNYGLSP-----DRQFVYLESDYSKLWRYSYTATYYIYDLS 136
Query: 237 TSVLTPVKGKDSKSPHPRLSYCHFSPSYRYIYFVEDNDLHVQSLDDQGDIYRITSDG-SN 295
V+G + P + Y +SP + +V N+++++ ++IT +G N
Sbjct: 137 NGEF--VRGNELPRP---IQYLCWSPVGSKLAYVYQNNIYLKQRPGDPP-FQITFNGREN 190
Query: 296 YVLNGRTDWVYEEELLXXXXXXXXXXXXSKLAFSRIDDAKVSNYNYQTFINGKQTPTLRS 355
+ NG DWVYEEE+L LA++ +D + Y ++ +Q P +
Sbjct: 191 KIFNGIPDWVYEEEMLATKYALWWSPNGKFLAYAEFNDTDIPVIAY-SYYGDEQYPRTIN 249
Query: 356 MKYPLPGASNPVICLFLYDLTNNSLNAIKET------------------TEEEGILLYYA 397
+ YP GA NPV+ +F+ D T + +E +E + L +
Sbjct: 250 IPYPKAGAKNPVVRIFIIDTTYPAYVGPQEVPVPAMIASSDYYFSWLTWVTDERVCLQWL 309
Query: 398 KWVDNNNLLFKVSDRESKILDTMIFNSENNQTKRLLTRDANTYNGWIEKCKEIIVVRRKG 457
K V N ++L RE D ++ Q +R GW V
Sbjct: 310 KRVQNVSVLSICDFRE----DWQTWDCPKTQEHIEESR-----TGW---AGGFFVSTPVF 357
Query: 458 QDINTGFLDILPDKNGYHHIFHFASSEDTNPRQITEGSWEVKEILGVEGESEIVYFQSNL 517
+ I DK+GY HI H+ N QIT G WE I V +S +++ SN
Sbjct: 358 SYDAISYYKIFSDKDGYKHI-HYIKDTVENAIQITSGKWEAINIFRVTQDS--LFYSSNE 414
Query: 518 F--HPMGLQLHTASL-----KDNSATLNLQQTEVLEYSKFTLSTSCKFAIKQYLGPDVPY 570
F +P ++ S+ T +L++ E +Y + S K+ GP +P
Sbjct: 415 FEEYPGRRNIYRISIGSYPPSKKCVTCHLRK-ERCQYYTASFSDYAKYYALVCYGPGIPI 473
Query: 571 TYAGDLWQLLNASEDDHSKILLTKNEHIEEAIQMYDYPVTDYKEITLEDYTEINYVEIKP 630
+ L+ D +L +N+ +E A++ P + K++ +++ T + Y I P
Sbjct: 474 S-------TLHDGRTDQEIKILEENKELENALKNIQLPKEEIKKLEVDEIT-LWYKMILP 525
Query: 631 KTFEPEKKYPLLVYVYGGPGSETFNTKFXXXXXXXXXXXXXXXVLKIEPRGTGGKGWNFK 690
F+ KKYPLL+ VYGGP S++ + F + ++ RGT +G
Sbjct: 526 PQFDRSKKYPLLIQVYGGPCSQSVRSVFAVNWISYLASKEGMVIALVDGRGTAFQGDKLL 585
Query: 691 SWANRNIGFWEPRDIINVTKKYIETQKDVIAQDKVAIWGWSYGGFTTLKTLEFDKGSVFK 750
R +G +E D I +K+IE I + ++AIWGWSYGG+ + L G +FK
Sbjct: 586 YAVYRKLGVYEVEDQITAVRKFIE--MGFIDEKRIAIWGWSYGGYVSSLALASGTG-LFK 642
Query: 751 YGVSVAPVTDWKYYDSVYSERYLGSPLSSDAYD--KNAKIKDYDSFKFTKRFLLMHGTAD 808
G++VAPV+ W+YY SVY+ER++G P D + KN+ + + +LL+HGTAD
Sbjct: 643 CGIAVAPVSSWEYYASVYTERFMGLPTKDDNLEHYKNSTVMARAEYFRNVDYLLIHGTAD 702
Query: 809 DNVHIQNTYEL 819
DNVH QN+ ++
Sbjct: 703 DNVHFQNSAQI 713
>7294364 [O] KOG2100 Dipeptidyl aminopeptidase
Length = 802
Score = 220 bits (561), Expect = 6e-57
Identities = 181/659 (27%), Positives = 293/659 (43%), Gaps = 43/659 (6%)
Query: 210 DYAILGSNVIKEYRHSSSGLYWLYNLKTSVLTPVKGKDSKSPHPRLSYCHFSPSYRYIYF 269
++ +L N K +R+S Y LYNL T + ++ + LS +SP +
Sbjct: 133 EFLLLAKNYKKNFRYSFLAEYDLYNLNTKEFIQLTIQNEQH---YLSMVQWSPVGNALVI 189
Query: 270 VEDNDLHVQSLDDQGDIYRITSDGSNYVLNGRTDWVYEEELLXXXXXXXXXXXXSKLAFS 329
D +L+ + +I +TSD +LNG DWVYEEE+ ++LAF
Sbjct: 190 NYDRNLYYKESALAQEI-ALTSDEQAGILNGIPDWVYEEEVFSSNVATWFNPSGTQLAFI 248
Query: 330 RIDDAKVSNYNYQTFINGK----QTPTLRSMKYPLPGASNPVICLFLYDLTN-------- 377
+ DD+ N+ + + Q P + + YP G+SNP + L + DL
Sbjct: 249 KFDDSSTHLINFPYYGDAGDLRYQYPLHQVIAYPKAGSSNPRVELVMVDLKRAVAGGDFV 308
Query: 378 NSLNAIKETTEEEGILLYYAKWVDNNNLLFKVSDRESKILDTMIFNSENNQTKRLLTRDA 437
+ E ++ WVD++N+L +R + F+ N R + A
Sbjct: 309 TVMPVPSALNTETDYIVTVVSWVDDDNVLSIWMNRIQNAAYVVTFDGLN----RKVIYSA 364
Query: 438 NTYNGWIEKCKEIIVVRRKGQDINTGFLDILPDKNGYHHI----FHFASSEDTNPRQITE 493
+ GW++ + ++ N L + N Y H+ ASSE +TE
Sbjct: 365 ESKTGWVD------LYTAPFRNRNGSRLAFVLPHNNYKHVQLLSSTVASSEPQALEPLTE 418
Query: 494 GSWEVKEILGVEGESEIVYFQSNLF-HPMGLQLHT----ASLKDNSATLNLQQTEVLEYS 548
G + V IL +G+++I+++ +N HP L L+ A T NL ++ ++ +
Sbjct: 419 GKYVVDSILHWDGKNDIIFYTANTEDHPEQLHLYAIRALAKQSPKCLTCNLIKSGDVQQT 478
Query: 549 KFTLS-TSCKFAIKQYLGPDVPYTYAGDLWQLLNASEDDHSKIL-LTKNEHIEEAIQMYD 606
F+ + + LGP +P T+ + W+ N S+ SK+L NE + ++
Sbjct: 479 YFSATFNDNNHIVITSLGPGIPTTHIYE-WKYEN-SQVVISKVLDWETNESLRAKLKGVA 536
Query: 607 YPVTDYKEITLEDYTEINYVEIKPKTFEPE--KKYPLLVYVYGGPGSETFNTKFXXXXXX 664
P + ++ + + P + KYP+LV VYGGP S + K+
Sbjct: 537 LPSHKILTVDIDGGFQAKVLLQLPPNLDTSGATKYPMLVDVYGGPDSYSVTNKWMVDWGT 596
Query: 665 XXXXXXXXXVLKIEPRGTGGKGWNFKSWANRNIGFWEPRDIINVTKKYIETQKDVIAQDK 724
KI+ RG+G +G + +G E D INVT+K + T + I D
Sbjct: 597 YLSSNQSVIYAKIDGRGSGLRGESLLHAIYLKLGTVEISDQINVTQK-LSTLFNYIDPDH 655
Query: 725 VAIWGWSYGGFTTLKTLEFDKGSVFKYGVSVAPVTDWKYYDSVYSERYLGSPLSSDAYDK 784
V IWGWSYGG+ L D+ VFK S+APVTDW YYDS+Y+ERY+G P +++
Sbjct: 656 VGIWGWSYGGYAAAMALANDEAKVFKCAASIAPVTDWAYYDSIYTERYMGLPNTNELGYA 715
Query: 785 NAKIKDYDSFKFTKRFLLMHGTADDNVHIQNTYELIDNFNLHSVRNYDMHIFPDSDHSI 843
N+++ K++LL+HGT DDNVH Q L N + + + D DH +
Sbjct: 716 NSRLSTMAVKLRGKKYLLVHGTLDDNVHYQQAMILAKNLERQDIL-FKQISYADEDHGL 773
>7297021 [O] KOG2100 Dipeptidyl aminopeptidase
Length = 745
Score = 216 bits (550), Expect = 1e-55
Identities = 191/699 (27%), Positives = 319/699 (45%), Gaps = 76/699 (10%)
Query: 189 LQFTFNEHKYSLESISIDYSLDYAILGSNVIKEYRHSSSGLYWLYNLKTSVLTPV-KGKD 247
L F N + + S+S D + ++ N+ +++RHS Y +++++T+ + KG+
Sbjct: 82 LHFELNNYVGATFSLSPDNTK--ILIRHNLTEKFRHSYIAQYDVFDIETNTTVQIHKGE- 138
Query: 248 SKSPHPRLSYCHFSPSYRYIYFVEDNDLHV---QSLDDQGDIYRITSDG-SNYVLNGRTD 303
+L YC +SP + +V N++ + +SL+ IT DG V NG D
Sbjct: 139 ------KLQYCGWSPLRDRLAYVYLNNVFIHFSESLE-----ISITDDGVDGVVYNGVPD 187
Query: 304 WVYEEELLXXXXXXXXXXXXSKLAFSRIDDAKVSNYNYQTFINGKQT----PTLRSMKYP 359
WVYEEE+L S+LA +D +V + Y + +G T P +KYP
Sbjct: 188 WVYEEEVLSSGSAIWWSSDGSRLAVGFFNDTEVETFTYFLYGDGATTFYQYPHEEQLKYP 247
Query: 360 LPGASNPVICLFLYDLTNN--SLNAIKETTEEEGI--LLYYAKWVDNNNLLFKVSDRESK 415
G+ NPV+ L +YD+++N +++ I + G +L W ++ +LL +R
Sbjct: 248 KSGSKNPVVSLRVYDVSDNDPTMHTIVAPVDIVGDDHILQSVVWSNSTHLLITWMNRRQN 307
Query: 416 ILDTMIFNSENN--QTKRLLTRDANTYNGWIE----KCKEIIVVRRKGQDINTGFLDILP 469
+ + E + + KRL GW++ KC G+ G+
Sbjct: 308 LTSIQSCSYEGDCVEVKRL-----EEPQGWVDISTPKCLST------GKSCIFGYFI--- 353
Query: 470 DKNGYHHIFHFASSEDTNPRQITEGSWEVKEILGVEGESEIVYFQSNLFHPMGLQLHTAS 529
+ +H +++ N Q + G++ V + G + + +Y+Q+ L + H S
Sbjct: 354 --DNWHQVWNLDLETGLNSWQ-SRGNFTVLSVYGYDEARDKLYYQATLPGDPSVY-HVFS 409
Query: 530 LKDNSATLNLQQTEV----LEYSKFTLSTSCKFAIKQYLGPDVPYTYAGDLWQLLNASED 585
N L+ Q + + T S S + GP+ YT ++ AS
Sbjct: 410 ---NDECLSCGQIDADGAACRSASGTFSKSFSYYTLSCTGPNPSYT------RIFEASTK 460
Query: 586 DHSKILLTKNEHIEEAIQMYDYPVTDYKEITLEDYTEINYVEIK-PKTFEPEKKYPLLVY 644
++ N + I+ P + +TL D + I Y ++ P F KKYPL+V
Sbjct: 461 T-LQVDWEPNTAYRKQIEEKLRPSYRFMNVTLADGS-IGYAKLALPPNFVETKKYPLIVV 518
Query: 645 VYGGPGSETFNTKFXXXXXXXXXXXXXXXVLKIEPRGTGGKGWNFKSWANRNIGFWEPRD 704
VY GP S F I+ RGTG KG + N ++G E D
Sbjct: 519 VYQGPNSVRVTNGFTLGYEAFVTTSRDTIYAYIDGRGTGNKGKDLLFSVNNDLGDHEVED 578
Query: 705 IINVTKKYIETQKDVIAQDKVAIWGWSYGGFTTLKTLEFDKGSVFKYGVSVAPVTDWKYY 764
+ VT+ +++ + ++ IWGWSYGG+ T KT+E D VF+ GVSVAPVT W YY
Sbjct: 579 QLFVTR-WMQQNLAFVDAERCGIWGWSYGGYMTAKTIEKDDDRVFQCGVSVAPVTSWLYY 637
Query: 765 DSVYSERYLGSPLSSD---AYDKNAKIKDYDSFKFTKRFLLMHGTADDNVHIQNTYELID 821
D++Y+ERY+G P D Y++++ + ++FK + FLL+HG+ DDNVH Q++ L
Sbjct: 638 DTIYTERYMGLPTDDDNLKKYNESSVFGNLENFK-SHDFLLIHGSGDDNVHYQHSLLLAK 696
Query: 822 NFNLHSVRNYDMHIFPDSDHSIYFHNAQRMVYEKI-YFW 859
++ ++ + D +H I NA +Y I FW
Sbjct: 697 LLQRQDIQ-FEEQTYTDENHGI--GNALPHLYHTIDAFW 732
>Hs22041021 [O] KOG2100 Dipeptidyl aminopeptidase
Length = 746
Score = 206 bits (525), Expect = 1e-52
Identities = 183/672 (27%), Positives = 295/672 (43%), Gaps = 51/672 (7%)
Query: 192 TFNEHKYSLESISIDYSLDYAILGSNVIKEYRHSSSGLYWLYNLKTSV---LTPVKGKDS 248
TF K S S+S D L Y +L +V + + +S + Y +YN+ T L P + +DS
Sbjct: 71 TFVTFKASRHSVSPD--LKYVLLAYDVKQIFHYSYTASYVIYNIHTREVWELNPPEVEDS 128
Query: 249 KSPHPRLSYCHFSPSYRYIYFVEDNDLHVQSLDDQGDIYRITSDGSNYVL-NGRTDWVYE 307
L Y + + + ++ +N+++ Q D + R+TS G ++ NG DW+YE
Sbjct: 129 V-----LQYAAWGVQGQQLIYIFENNIYYQP-DIKSSSLRLTSSGKEEIIFNGIADWLYE 182
Query: 308 EELLXXXXXXXXXXXXSKLAFSRIDDAKVSNYNYQTFINGKQTPTLRSMKYPLPGASNPV 367
EELL +LAF I+D+ V F G P + YP G NP
Sbjct: 183 EELLHSHIAHWWSPDGERLAFLMINDSLVPTMVIPRF-TGALYPKGKQYPYPKAGQVNPT 241
Query: 368 ICLF---LYDLTNNSLNAIKETTEEEGILLYYAKWVDNNNLLFKVSDRESKILDTMIFNS 424
I L+ LY T+ ++ + + KWV N + + +R I + +
Sbjct: 242 IKLYVVNLYGPTHTLELMPPDSFKSREYYITMVKWVSNTKTVVRWLNRAQNISILTVCET 301
Query: 425 ENNQTKRLLTRDANTYNGWIEKCKEIIVVRRKGQDINTGFLDILPDKNG----YHHIFHF 480
+ ++T W+ + E V R G F +P K G +HH+ F
Sbjct: 302 TTGACSKKYEMTSDT---WLSQQNEEPVFSRDGSK----FFMTVPVKQGGRGEFHHVAMF 354
Query: 481 ---ASSEDTNPRQITEGSWEVKEILGVEGESEIVYFQSNLFHPMGLQLHTASLKDNSATL 537
+ SE R +T G+WEV +IL + ++ +YF S P G QL++AS + L
Sbjct: 355 LIQSKSEQITVRHLTSGNWEVIKILAYDETTQKIYFLSTESSPRGRQLYSASTE---GLL 411
Query: 538 NLQ------QTEVLEYSKFTLSTSCKFAIKQYLGPDVPYTYAGDLWQLLNASEDDHSKIL 591
N Q E Y + S + + GP VP L+++++ +
Sbjct: 412 NRQCISCNFMKEQCTYFDASFSPMNQHFLLFCEGPRVPVVS-------LHSTDNPAKYFI 464
Query: 592 LTKNEHIEEAIQMYDYPVTDYKEITLEDYTEINYVEIKPKTFEPEKKYPLLVYVYGGPGS 651
L N ++EAI + K + ++DY E+ PK F +Y LL+ + PG
Sbjct: 465 LESNSMLKEAILKKKIGKPEIKILHIDDY-ELPLQLSLPKDFMDRNQYALLLIMDEEPGG 523
Query: 652 ETFNTKFXXXXXXXXXXXXXXXVLKIEPRGTGGKGWNFKSWANRNIGFWEPRDIINVTKK 711
+ KF V + + RG+G +G +R +G E +D I K
Sbjct: 524 QLVTDKFHIDWDSVLIDMDNVIVARFDGRGSGFQGLKILQEIHRRLGSVEVKDQITAVKF 583
Query: 712 YIETQKDVIAQDKVAIWGWSYGGFTTLKTLEFDKGSVFKYGVSVAPVTDWKYYDSVYSER 771
++ I +++I+G YGG+ L+ D+ +FK G VAP+TD K Y S +SER
Sbjct: 584 LLKLP--YIDSKRLSIFGKGYGGYIASMILKSDE-KLFKCGSVVAPITDLKLYASAFSER 640
Query: 772 YLGSPLSSDAYDKNAKIKDYDSFKFTKRFLLMHGTADDNVHIQNTYELIDNFNLHSVRNY 831
YLG P ++ + A + + L++HGTAD VH Q++ ELI + V NY
Sbjct: 641 YLGMPSKEESTYQAASVLHNVHGLKEENILIIHGTADTKVHFQHSAELIKHLIKAGV-NY 699
Query: 832 DMHIFPDSDHSI 843
M ++PD H++
Sbjct: 700 TMQVYPDEGHNV 711
>CE21196 [O] KOG2100 Dipeptidyl aminopeptidase
Length = 799
Score = 191 bits (485), Expect = 4e-48
Identities = 157/595 (26%), Positives = 268/595 (44%), Gaps = 37/595 (6%)
Query: 269 FVEDNDLHVQSLDDQGDIYRITSDGSNYVLNGRTDWVYEEELLXXXXXXXXXXXXSKLAF 328
FVE N ++ QS ++ + R+ S+G + ++G DW+YEEE+ +LA+
Sbjct: 199 FVESNKIYYQSSPEEEGLTRV-SNGGEHTVDGLFDWIYEEEIFGRKDAMWWSTKGDQLAY 257
Query: 329 SRIDDAKVSNYNYQTFINGKQTPTLRSMKYPLPGASNPVICLFLYDLTNNSLNAIKETTE 388
+ D+ N + +T+ + P + YP A V+ + + N ++
Sbjct: 258 ASYDNHLTKNVSLKTYHRLEPYPIDTNFHYPKTFAK--VLPTYTLSIWNKKTEQSRQLDV 315
Query: 389 EEGILLYY-----AKWVDNNNLLFKVSDRESKILDTMIFNSENNQTK--RLLTRDANTYN 441
+ L Y KW++ N VS ++ + + + T RL
Sbjct: 316 QLKDSLSYHYLLAVKWLEINGTEQLVSVWTNRYQNEVALTICDWDTAICRLEFEYKYASK 375
Query: 442 GWIEKCKEIIVVRRKGQDINTGFLDILPDK--NGYHHI--FHFASSEDTNPRQITEGSWE 497
W+ + + +T F + DK N + + + + P+ + G ++
Sbjct: 376 RWVTHDDFHSITSFE----DTLFFLLPHDKRDNAFQQVASLRLSHGQLRTPKFLNLGEYD 431
Query: 498 VKEILGVEGESEIVYFQSNLFHPMGLQLHTASLKD---NSATLNLQQTEVLEYSKFTLST 554
V I G+ E+ ++F + P L + SL D NSA + +++ +
Sbjct: 432 VTSINGINKETRTIFFHAAAPKPSHRSLFSYSLADESRNSAYCISCSIKNCTWAQAQMDD 491
Query: 555 SCKFAIKQYLGPDVPYTYAGDLWQLLNASEDDHSKILLTKN--EHIEEAIQMYDYPVTDY 612
K AI GP P+T +L ++ + + +H+ +L K +EEA PV
Sbjct: 492 QMKTAIVSCKGPAAPHTAIVNLTRMDSDKKTEHANLLYDKTYQNRVEEA----GLPVIIK 547
Query: 613 KEITL-EDYTEINYVEIKPKTFEPEKKY--PLLVYVYGGPGSETFNTKFXXXXXXXXXXX 669
+ I + +D+ + + I + +K PL+V+VYGGP +
Sbjct: 548 ETIKISDDFDALIKLSIPKDIYNRDKHQAIPLIVHVYGGPNDQNTKEATQIGIEEVVASA 607
Query: 670 XXXXVLKIEPRGTGGKGWNFKSWANRNIGFWEPRDIINVTKKYIETQKDVIAQDKVAIWG 729
+L+I+ RG+GG+GW ++S +G E D I K + + ++ +VA++G
Sbjct: 608 SQAAILRIDGRGSGGRGWKYRSAIYGQLGTVEVEDQIKAIKVVLRLYRHLLDARRVAVFG 667
Query: 730 WSYGGFTTLKTLEFDKGSVFKYGVSVAPVTDWKYYDSVYSERYLG-SPLSSDAYDKNAKI 788
WSYGGF TL + FK VSVAPVT++ YYD+ Y+ERY+G +PL S +
Sbjct: 668 WSYGGFMTLSMVNEAPEQFFKCAVSVAPVTNFAYYDATYTERYMGDAPLES----YSDVT 723
Query: 789 KDYDSFKFTKRFLLMHGTADDNVHIQNTYELIDNFNLHSVRNYDMHIFPDSDHSI 843
K D+FK T R LLMHG DDNVH QN+ LID V ++D+ ++P+ HS+
Sbjct: 724 KKLDNFKST-RLLLMHGLLDDNVHFQNSAILIDELQNRGV-DFDLMVYPNQAHSL 776
>CE21195 [O] KOG2100 Dipeptidyl aminopeptidase
Length = 779
Score = 191 bits (485), Expect = 4e-48
Identities = 157/595 (26%), Positives = 268/595 (44%), Gaps = 37/595 (6%)
Query: 269 FVEDNDLHVQSLDDQGDIYRITSDGSNYVLNGRTDWVYEEELLXXXXXXXXXXXXSKLAF 328
FVE N ++ QS ++ + R+ S+G + ++G DW+YEEE+ +LA+
Sbjct: 179 FVESNKIYYQSSPEEEGLTRV-SNGGEHTVDGLFDWIYEEEIFGRKDAMWWSTKGDQLAY 237
Query: 329 SRIDDAKVSNYNYQTFINGKQTPTLRSMKYPLPGASNPVICLFLYDLTNNSLNAIKETTE 388
+ D+ N + +T+ + P + YP A V+ + + N ++
Sbjct: 238 ASYDNHLTKNVSLKTYHRLEPYPIDTNFHYPKTFAK--VLPTYTLSIWNKKTEQSRQLDV 295
Query: 389 EEGILLYY-----AKWVDNNNLLFKVSDRESKILDTMIFNSENNQTK--RLLTRDANTYN 441
+ L Y KW++ N VS ++ + + + T RL
Sbjct: 296 QLKDSLSYHYLLAVKWLEINGTEQLVSVWTNRYQNEVALTICDWDTAICRLEFEYKYASK 355
Query: 442 GWIEKCKEIIVVRRKGQDINTGFLDILPDK--NGYHHI--FHFASSEDTNPRQITEGSWE 497
W+ + + +T F + DK N + + + + P+ + G ++
Sbjct: 356 RWVTHDDFHSITSFE----DTLFFLLPHDKRDNAFQQVASLRLSHGQLRTPKFLNLGEYD 411
Query: 498 VKEILGVEGESEIVYFQSNLFHPMGLQLHTASLKD---NSATLNLQQTEVLEYSKFTLST 554
V I G+ E+ ++F + P L + SL D NSA + +++ +
Sbjct: 412 VTSINGINKETRTIFFHAAAPKPSHRSLFSYSLADESRNSAYCISCSIKNCTWAQAQMDD 471
Query: 555 SCKFAIKQYLGPDVPYTYAGDLWQLLNASEDDHSKILLTKN--EHIEEAIQMYDYPVTDY 612
K AI GP P+T +L ++ + + +H+ +L K +EEA PV
Sbjct: 472 QMKTAIVSCKGPAAPHTAIVNLTRMDSDKKTEHANLLYDKTYQNRVEEA----GLPVIIK 527
Query: 613 KEITL-EDYTEINYVEIKPKTFEPEKKY--PLLVYVYGGPGSETFNTKFXXXXXXXXXXX 669
+ I + +D+ + + I + +K PL+V+VYGGP +
Sbjct: 528 ETIKISDDFDALIKLSIPKDIYNRDKHQAIPLIVHVYGGPNDQNTKEATQIGIEEVVASA 587
Query: 670 XXXXVLKIEPRGTGGKGWNFKSWANRNIGFWEPRDIINVTKKYIETQKDVIAQDKVAIWG 729
+L+I+ RG+GG+GW ++S +G E D I K + + ++ +VA++G
Sbjct: 588 SQAAILRIDGRGSGGRGWKYRSAIYGQLGTVEVEDQIKAIKVVLRLYRHLLDARRVAVFG 647
Query: 730 WSYGGFTTLKTLEFDKGSVFKYGVSVAPVTDWKYYDSVYSERYLG-SPLSSDAYDKNAKI 788
WSYGGF TL + FK VSVAPVT++ YYD+ Y+ERY+G +PL S +
Sbjct: 648 WSYGGFMTLSMVNEAPEQFFKCAVSVAPVTNFAYYDATYTERYMGDAPLES----YSDVT 703
Query: 789 KDYDSFKFTKRFLLMHGTADDNVHIQNTYELIDNFNLHSVRNYDMHIFPDSDHSI 843
K D+FK T R LLMHG DDNVH QN+ LID V ++D+ ++P+ HS+
Sbjct: 704 KKLDNFKST-RLLLMHGLLDDNVHFQNSAILIDELQNRGV-DFDLMVYPNQAHSL 756
>CE05324 [O] KOG2100 Dipeptidyl aminopeptidase
Length = 829
Score = 182 bits (462), Expect = 2e-45
Identities = 176/731 (24%), Positives = 317/731 (43%), Gaps = 49/731 (6%)
Query: 169 DDIIVAKRLNDKDFRKLISPLQFTFNEHKYSLESISIDYSLDYAILGSNVIKEYRHSSSG 228
DD + K++ ++ F E+ +L S ++ YA V + +RHS+
Sbjct: 120 DDFTIRKQMKKIPLGSSVAEPFFNNGEYVKALSS-----NMKYAYGSKKVNELWRHSAEY 174
Query: 229 LYWLYNLKTSVLTPVKGKDSKSPHPRLSYCHFSP--SYRYIYFVEDNDLHVQSLDDQGD- 285
LY + + ++ + + + +++P S +V + +L+ Q ++ D
Sbjct: 175 LYHIVKINNKTVSTEQWHVGPEENSLIQAFYWNPNASSNDFVYVHNYNLYYQKDPEKPDG 234
Query: 286 IYRITSDGSNYVLNGRTDWVYEEELLXXXXXXXXXXXXSKLAFSRIDDAKVSNYNYQTFI 345
++T GS + G +W+YEEE+L +++ R DD +V+ +
Sbjct: 235 AIQLTVGGSTFNRFGLANWLYEEEILEASSAVWWSPSGRYVSYLRFDDREVNRIFLPKYT 294
Query: 346 NGKQTPTLRSMKYPLPGA-SNPVICLFLYDLTNNSLNAIKETTEEEGILL----YYA--- 397
+ + YP G +N ++ +++D N+ I ET + YY
Sbjct: 295 DDDSYVEYFELPYPKAGVQNNTLVTQYIWDSENHK---IVETAPPNELSAANGDYYVLTN 351
Query: 398 KWVDNNNLLFKVSDRESKILDTMIFNSENNQTKRLLTRD-----ANTYNGWIEKCKEIIV 452
KW+ + SD + L T+ N + N L + A ++ I+ +++ V
Sbjct: 352 KWI---TMPRNGSDLGEERLVTVWANRDQNHVYFSLCNEQDCVMALSFQFSIDN-RQLWV 407
Query: 453 VRRKGQDI---NTGFLDILPDK----NGYHHIFHFASSEDTNPRQITEG---SWEVKEIL 502
+ + + TGFL +LP K N Y+H+ H + T +IT+ +++V +L
Sbjct: 408 SPKDVRGVFPTETGFLTVLPHKHDDGNIYNHVAH-VELDGTGTGKITKWIGENFDVILVL 466
Query: 503 GVEGESEIVYFQS--NLFHPMGLQLHTASLKDNSATLNLQQTEVLEYSKFTLSTSCKFAI 560
G + + + F + + + ++ N T + T+ E K TL +
Sbjct: 467 GYSSKIDALTFSAYGDGVGEFSTYIVREAMYSNKKTTLQKVTDQFEDCK-TLGSQSADPT 525
Query: 561 KQYLGPDVPYTYAGDLWQLLNASEDDHSKILLTKNEHIEEAIQMYDYPVTDYKEITLEDY 620
Q + + L++ D KI+L E +A+ +D P + ++ L
Sbjct: 526 GQRIVVQCEKPFDNTRLYLVDVV-DTTKKIML---EGGTKAVIPFDVPNMKFGKLKLPSG 581
Query: 621 TEINYVEIKPKTFEPEKKYPLLVYVYGGPGSETFNTKFXXXXXXXXXXXXXXXVLKIEPR 680
+ +Y+ + P K PLL+ +YGGP S+ K +I+ R
Sbjct: 582 IDGHYMMLTPANLLDGAKIPLLLDIYGGPDSKQVFQKTPTAHAIQIVSQYDIAYARIDVR 641
Query: 681 GTGGKGWNFKSWANRNIGFWEPRDIINVTKKYIETQKDVIAQDKVAIWGWSYGGFTTLKT 740
GTGG+GW+ K R +G E D +++ + +I T I +D++A+ GWSYGGF T K
Sbjct: 642 GTGGRGWDVKEAVYRKLGDAEVVDTLDMIRAFINTF-GFIDEDRIAVMGWSYGGFLTSKI 700
Query: 741 LEFDKGSVFKYGVSVAPVTDWKYYDSVYSERYLGSPLSSDAYDKNAKIKDYDSFKFTKRF 800
D+G + K +S+APVTD+KYYDS Y+ERYLG P + N + + ++
Sbjct: 701 AIKDQGELVKCAISIAPVTDFKYYDSAYTERYLGQPAENLQGYINTNVIPHARNVTNVKY 760
Query: 801 LLMHGTADDNVHIQNTYELIDNFNLHSVRNYDMHIFPDSDHSIYFHNAQRMVYEKIYFWI 860
LL HG DDNVH QN+ + + + ++ ++ + HS+ H + E F +
Sbjct: 761 LLAHGERDDNVHYQNSARWSEALQQNGI-HFTQLVYANEAHSL-SHKLFHLYGEVQRFLM 818
Query: 861 KDAFLGRLDSL 871
D F LD L
Sbjct: 819 NDCFKSNLDLL 829
>At5g24260 [O] KOG2281 Dipeptidyl aminopeptidases/acylaminoacyl-peptidases
Length = 746
Score = 164 bits (416), Expect = 4e-40
Identities = 172/730 (23%), Positives = 311/730 (42%), Gaps = 56/730 (7%)
Query: 141 FIAPPAIEYIPKEKDSGLYLTMEKNSQKDDIIVAKRLNDKDFRKLISPLQFTFNEHKYSL 200
++AP A+ + P + + EKN ++ + A +N + + SP +E S
Sbjct: 21 YVAPTAVSFSPDDSLITYLFSPEKNLKRR--VYAFDVNKGESNLVFSPPDGGVDESNISP 78
Query: 201 ESISIDYSLDYAILGSNVIKEYRHSSSGLYWLYNLKTSVLTPVKGKD-SKSPHPRLSYC- 258
E L LG + + +S + + L V KD S SP+P L
Sbjct: 79 EEKLRRERLRERGLGVTRYEWVKTNSKMRFIVVPLPAGVYM----KDLSSSPNPELIVPS 134
Query: 259 ---------HFSPSYRYIYFVEDNDLHVQSLDDQGDIYRITSDGSNYVLN-GRTDWVYEE 308
SP+ ++ +V +++LHV +L + ++TS + L+ G +++ +E
Sbjct: 135 SPTSPIIDPRLSPNGLFLAYVRESELHVLNLL-KNQTQQLTSGANGSTLSHGLAEYIAQE 193
Query: 309 ELLXXXXXXXXXXXXSKLAFSRIDDAKVSNYNYQTFINGKQTPTLRSMK---YPLPGASN 365
E+ +A++ +D +++ + GK++ + + YP GA N
Sbjct: 194 EM-DRRNGYWWSLDSKFIAYTEVDSSQIPLFRIMH--QGKRSVGSEAQEDHAYPFAGALN 250
Query: 366 PVICLFLYDLTNNS----LNAI---KETTEEEGILLYYAKWVDNNNLLFKVSDRESKILD 418
+ L + +N + + TE+E L W+ N L+ +V +R L
Sbjct: 251 STLRLGVVSSAGGGKTTWMNLVCGGRGNTEDE--YLGRVNWLPGNVLIVQVLNRSQSKLK 308
Query: 419 TMIFNSENNQTKRLLTRDANTYNGWIEKCKEIIVVRRKGQDINTGFLDILPDKNGYHHIF 478
+ F+ Q LLT +++T W+ + + +G ++ G+ H++
Sbjct: 309 IISFDINTGQGNVLLTEESDT---WVTLHDCFTPLEKVPSSRGSGGFIWASERTGFRHLY 365
Query: 479 HFASSEDTNPRQITEGSWEVKEILGVEGESEIVYFQSNLFHPMGLQLHTASLK--DNSAT 536
+ S+ T IT G W V++I GV +VYF L P+ L+ A L+ + S
Sbjct: 366 LY-ESDGTCLGAITSGEWMVEQIAGVNEPMSLVYFTGTLDGPLETNLYCAKLEAGNTSRC 424
Query: 537 LNLQQTEVLEYSKFTLSTSCKFAIKQYLGPDVPYTYAGDLWQLLNASEDDHSKILLTKNE 596
++ T L K + + D P + L + S+ KIL +
Sbjct: 425 QPMRLTHGKGKHIVVLDHQMKNFVDIHDSVDSPPRVS-----LCSLSDGTVLKILYEQTS 479
Query: 597 HIEEAIQMYDYPVTDYKEITLEDYTEINYVEI-KPKT--FEPEKKYPLLVYVYGGPGSET 653
I+ ++ ++ +I D Y + KP + F P Y ++ VYGGP +
Sbjct: 480 PIQ-ILKSLKLEPPEFVQIQANDGKTTLYGAVYKPDSSKFGPPP-YKTMINVYGGPSVQL 537
Query: 654 FNTKFXXXXXXXXXXXXXXXVL--KIEPRGTGGKGWNFKSWANRNIGFWEPRDIINVTKK 711
+ +L K++ RGT +G F+SW N G+ + D + K
Sbjct: 538 VYDSWINTVDMRTQYLRSRGILVWKLDNRGTARRGLKFESWMKHNCGYVDAEDQVTGAKW 597
Query: 712 YIETQKDVIAQDKVAIWGWSYGGFTTLKTLEFDKGSVFKYGVSVAPVTDWKYYDSVYSER 771
IE + + D + ++GWSYGG+ + TL +F VS APVT W YDS Y+E+
Sbjct: 598 LIE--QGLAKPDHIGVYGWSYGGYLSA-TLLTRYPEIFNCAVSGAPVTSWDGYDSFYTEK 654
Query: 772 YLGSPLSSDAYDKNAKIKDYDSFKFTKRFLLMHGTADDNVHIQNTYELIDNFNLHSVRNY 831
Y+G P + Y K++ + + ++ +L+HG D+NVH ++T L+ N + + + Y
Sbjct: 655 YMGLPTEEERYLKSSVMHHVGNLTDKQKLMLVHGMIDENVHFRHTARLV-NALVEAGKRY 713
Query: 832 DMHIFPDSDH 841
++ IFPD H
Sbjct: 714 ELLIFPDERH 723
>SPAC14C4.15c [O] KOG2100 Dipeptidyl aminopeptidase
Length = 743
Score = 137 bits (344), Expect = 9e-32
Identities = 95/315 (30%), Positives = 148/315 (46%), Gaps = 37/315 (11%)
Query: 552 LSTSCKFAIKQYLGPDVPYTYAGDLWQLLNASEDDHSKILLTK----------------- 594
+S + + YLGP++P + + + ++ +DHSK L
Sbjct: 416 VSNDQNYLLVNYLGPEIPKQFIYSIHEDKVSTSNDHSKNNLPSDSSSTSLGKVKLELCNS 475
Query: 595 ---NEHIEEAIQMYDYPVTDYKEITLEDYTEINYV-EIKPKTFEPEKKYPLLVYVYGGPG 650
NE + + + +P +K I +++ T Y+ EI+P F P K+YP + ++YG P
Sbjct: 476 LETNEELIITKEKFAFPSVFFKVIKVKNITA--YIQEIRPPNFNPRKRYPTVFHLYGAPQ 533
Query: 651 SETFNTKFXXXXXXXXXXXXXXXVLKIEPRGTGGKGWN--FKSWANRNIGFWEPRDIINV 708
S K+ V+K++ F I W I +
Sbjct: 534 SALVTGKYEMDINELMASVYNFLVIKVDIVDISDVSGQHLFSDSHELIIKSW-----IEL 588
Query: 709 TKKYIETQKDVIAQDKVAIWGWSYGGFTTLKTLEFDKGSVFKYGVSVAPVTDWKYYDSVY 768
+ Y++T I + +V IWGWS+GG+ TLK LE K G VAPVTDW+YYD+ Y
Sbjct: 589 LRSYVDTP--YIDRHRVGIWGWSFGGYLTLKILE--NADFIKTGAVVAPVTDWRYYDAYY 644
Query: 769 SERYLG--SPLSSDAYDKNAKIKDYDSFKFTKRFLLMHGTADDNVHIQNTYELIDNFNLH 826
SE LG S ++ YDK A + ++F+ L++HGT+DDNVHI+NT +L
Sbjct: 645 SENLLGAYSKQTTAIYDKTA-VHYSENFRKLCGLLVLHGTSDDNVHIENTMQLTKAMVEK 703
Query: 827 SVRNYDMHIFPDSDH 841
V NY I P+++H
Sbjct: 704 GVYNYYPFIVPNANH 718
>Hs18450280 [O] KOG2281 Dipeptidyl aminopeptidases/acylaminoacyl-peptidases
Length = 882
Score = 130 bits (326), Expect = 1e-29
Identities = 100/361 (27%), Positives = 164/361 (44%), Gaps = 15/361 (4%)
Query: 491 ITEGSWEVKEILG----VEGESEIVYFQSNLFHPMGLQLHTASLKDNSATLNLQQTEVLE 546
IT G WEV G V+ +VYF+ P+ L+ S + L T+
Sbjct: 498 ITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRL--TDRGY 555
Query: 547 YSKFTLSTSCKFAIKQYLGPDVPYTYAGDLWQLLNASEDDHSKILLTKNEHIEEAIQMYD 606
+S C F I +Y P+ + L++L + +D K ++ A + D
Sbjct: 556 SHSCCISQHCDFFISKYSNQKNPHCVS--LYKLSSPEDDPTCKTKEFWATILDSAGPLPD 613
Query: 607 YPVTDYKEITLEDYTEINYVEIKPKTFEPEKKYPLLVYVYGGPGSETFNTKFXXXXXXXX 666
Y + + + KP +P KKYP ++++YGGP + N +F
Sbjct: 614 YTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRL 673
Query: 667 XXXXXXX--VLKIEPRGTGGKGWNFKSWANRNIGFWEPRDIINVTKKYIETQKDVIAQDK 724
V+ I+ RG+ +G F+ +G E D + + Y+ ++ D I D+
Sbjct: 674 NTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQ-YLASRYDFIDLDR 732
Query: 725 VAIWGWSYGGFTTLKTLEFDKGSVFKYGVSVAPVTDWKYYDSVYSERYLGSP-LSSDAYD 783
V I GWSYGG+ +L L + +F+ ++ APVT W +YD+ Y+ERY+G P + Y
Sbjct: 733 VGIHGWSYGGYLSLMAL-MQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYY 791
Query: 784 KNAKIKDYDSF-KFTKRFLLMHGTADDNVHIQNTYELIDNFNLHSVRNYDMHIFPDSDHS 842
+ + F R LL+HG D+NVH +T L+ +F + + + YD+ I+P HS
Sbjct: 792 LGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILL-SFLVRAGKPYDLQIYPQERHS 850
Query: 843 I 843
I
Sbjct: 851 I 851
>7301225 [O] KOG2281 Dipeptidyl aminopeptidases/acylaminoacyl-peptidases
Length = 1102
Score = 128 bits (322), Expect = 3e-29
Identities = 79/220 (35%), Positives = 123/220 (55%), Gaps = 9/220 (4%)
Query: 629 KPKTFEPEKKYPLLVYVYGGPGSETFNTKFXXXXXXXXXXXXXXX--VLKIEPRGTGGKG 686
KP FE KYP ++ VYGGP +T N F V+ I+ RG+ +G
Sbjct: 867 KPHNFELGVKYPTVLNVYGGPEVQTVNNTFKGKHQLRMHMLAAQGYCVICIDSRGSRHRG 926
Query: 687 WNFKSWANRNIGFWEPRDIINVTKKYIETQKDVIAQDKVAIWGWSYGGFTTLKTL-EFDK 745
F+S +G E D ++ + + Q I D+VAI GWSYGG+ +L L ++ K
Sbjct: 927 KRFESHIRGRMGQVELTDQVDALRS-LSDQLGYIDMDRVAIHGWSYGGYLSLMGLVQYPK 985
Query: 746 GSVFKYGVSVAPVTDWKYYDSVYSERYLGSPLSSDA-YDKNAKIKDYDSF-KFTKRFLLM 803
+FK ++ APVT+W+YYD+ Y+ERY+ P +++A Y + ++ +SF + KR LL+
Sbjct: 986 --IFKVAIAGAPVTNWEYYDTGYTERYMDMPQNNEAGYSAGSVLEYVNSFPEEDKRLLLI 1043
Query: 804 HGTADDNVHIQNTYELIDNFNLHSVRNYDMHIFPDSDHSI 843
HG D+NVH +T LI N + + Y++H+FP+ HS+
Sbjct: 1044 HGLIDENVHFCHTSRLISALN-KANKPYEVHLFPEERHSL 1082
>7293308 [O] KOG2100 Dipeptidyl aminopeptidase
Length = 1048
Score = 127 bits (318), Expect = 1e-28
Identities = 162/711 (22%), Positives = 277/711 (38%), Gaps = 121/711 (17%)
Query: 267 IYFVEDNDLHVQSLDDQGDIYRITSDGSN--------YVLNGRTDWVYEE--ELLXXXXX 316
I FV ND++ + + RIT GS V NG DW+YE EL
Sbjct: 251 IAFVHHNDIYYKPKVQGELVCRITQTGSGSLEGESTGVVFNGVPDWMYENVPELESRRSS 310
Query: 317 XXXXXXXSKLAFSRIDDAKVSNYNYQTFINGKQTPTLRSMKYPLPGASNPVICLFLYDLT 376
LAF +D++V+ Y Y + + P + S +YP G+ NP + + + +L+
Sbjct: 311 MEFSPDGLFLAFLSYNDSEVNEYKYTWMGDDIKYPAVMSQRYPKTGSRNPNVTVNVVNLS 370
Query: 377 NNSL---NAIKETTE-EEGILLYYAKWVDNNNLLFKVSDRESKILDTMIFNSENNQTKRL 432
IK +E G + W + +L V++RE T++ + + + +
Sbjct: 371 VIKYIFPTQIKLPSELSNGSYVGGLTWASSTDLSVTVTNREQTKATTVLCRAPHFHCQAV 430
Query: 433 LTRDANTYNGWIEKCKE-IIVVRRKGQ-------------------------------DI 460
T + +GW+ + I VR +G +I
Sbjct: 431 HT-EVTINDGWVLPSERPIFSVRNQGHNRLGKMVQNAEEIQAESQNVNVTDGQTHTTHEI 489
Query: 461 NTG--FLDILPDKNGYH-HIFH--FASSEDTNPRQITEGSWEVKEILGVEGESEIVYFQS 515
+ G L LP ++G H H H F SS D P +T G +EV EI+G + EIVYF +
Sbjct: 490 SNGGYLLKRLPVRDGEHGHYRHVVFISSLDRRPVPLTMGRFEVTEIVGWDEPHEIVYFMA 549
Query: 516 NLF-HPMGLQLHTASLKDN----------------------SATLNLQQTEVLE------ 546
P L+ SLK N +T L + + +
Sbjct: 550 APEKRPGERHLYKISLKLNVTESNRTYITSTSPTCLTCDNTESTYRLHRARISQRGDRWE 609
Query: 547 --------------------YSKFTLSTSCKFAIKQYLGPDVPYTYAGDLWQLLNASEDD 586
+++ S + +++ LGP+ P Y L+ + +D
Sbjct: 610 DIVARLEPDDCLYDIPKNCLFNRVQFSQDYSYYVQECLGPEAPSVY------LVETASND 663
Query: 587 HSKILLTKNEHIEEAIQMYDYPV--TDYKEITLEDYTEINYVEIKPKTFEPEKKYPLLVY 644
+L + + + P T EI + ++ E + +PL+++
Sbjct: 664 KIYVL-NAGDVLRHRLSQLAIPQSRTFSVEIRHGFHAQVRLFLPPGMREEEDVAFPLVLH 722
Query: 645 VYGGPGSETFNTKFXXXXXXXXXXXXXXXVLKIEPRGTGGKGWNFKSWANRNIGFWEPRD 704
V PGS+ +F V +I+ RG+G +G ++ + +G E D
Sbjct: 723 VDASPGSQLVTERFHVDWNWYLASQRSFIVAQIDGRGSGFQGELLRTQVHGKLGTVEVED 782
Query: 705 IINVTKKYIETQKDVIAQDKVAIWGWSYGGFTTLKTLEFDKGSVFKYGVSVAPVTDWKYY 764
+ V Y+ I ++ +GW YGG+ + L D V + V++ P+ ++ ++
Sbjct: 783 QLGVLT-YLRDNLKFIDPLRICAFGWGYGGYASSMMLIDDSQQVLQCAVAINPIVNFGFH 841
Query: 765 DSVYSERYLGSPLSSD---AYDKNAKIKDYDSFKFTKRFLLMHGTADDNVHIQNTYELID 821
S ++ERY+ PL D A + + K + +LMHGTAD VH ++T L+
Sbjct: 842 YSFFTERYI--PLKGDYLRALQEADLTMKAGNIK-GRNLMLMHGTADTLVHQEHTLMLVR 898
Query: 822 NFNLHSVRNYDMHIFPDSDHSIYFHNAQRMVYEKIYFWIKDAFLGRLDSLE 872
V+ + ++PD DH+I + VY K W D G +D E
Sbjct: 899 ALVEQQVK-FRHQVYPDEDHAI--ARSLSHVY-KTMEWYFDECFGPVDDNE 945
>Hs21040237 [O] KOG2281 Dipeptidyl aminopeptidases/acylaminoacyl-peptidases
Length = 863
Score = 124 bits (312), Expect = 5e-28
Identities = 180/808 (22%), Positives = 324/808 (39%), Gaps = 124/808 (15%)
Query: 143 APPAIEYIPKEKDSG------LYLTMEKNSQKDDII---VAKRLNDK-----DFRKLISP 188
AP +++ K +SG YL M S+++ ++ + K++ + +++++
Sbjct: 52 APHDFQFVQKTDESGPHSHRLYYLGMPYGSRENSLLYSEIPKKVRKEALLLLSWKQMLDH 111
Query: 189 LQFTFNEHKYSLESISIDYSLDYAILGSNVIKEYR-HSSSGLYWLYNLKTSV-------- 239
Q T + YS E + + G I Y HS SGL+ L+ S+
Sbjct: 112 FQATPHHGVYSREEELLRERKRLGVFG---ITSYDFHSESGLF-LFQASNSLFHCRDGGK 167
Query: 240 ----LTPVKGKDSKSP--HPRLS--YCHFSPSYRYIYFVEDNDLHVQSLDDQGDIYRIT- 290
++P+K + K+ PR+ C P++ F+ ++DL V +++ G+ R+T
Sbjct: 168 NGFMVSPMKPLEIKTQCSGPRMDPKICPADPAF--FSFINNSDLWVANIET-GEERRLTF 224
Query: 291 -SDGSNYVLN-----GRTDWVYEEEL---------LXXXXXXXXXXXXSKLAFSRIDDAK 335
G + VL+ G +V +EE ++ + +D+++
Sbjct: 225 CHQGLSNVLDDPKSAGVATFVIQEEFDRFTGYWWCPTASWEGSEGLKTLRILYEEVDESE 284
Query: 336 VSNYNYQT-FINGKQTPTLRSMKYPLPGASNPVICLFLYDLTNNSLNAIKETTEEEGI-- 392
V + + + ++T + R YP G+ NP I L L + +S I T E+E +
Sbjct: 285 VEVIHVPSPALEERKTDSYR---YPRTGSKNPKIALKLAEFQTDSQGKIVSTQEKELVQP 341
Query: 393 ---------LLYYAKWVDNNNLLFKVS-DRESKILDTMIF-------NSENNQTK----R 431
+ A W + + + DR + L ++ ++EN + + R
Sbjct: 342 FSSLFPKVEYIARAGWTRDGKYAWAMFLDRPQQWLQLVLLPPALFIPSTENEEQRLASAR 401
Query: 432 LLTRDANTY-------NGWIEKCKEIIVVRRKGQDINTGFLDILPDKNGYHHIFHFAS-- 482
+ R+ Y N WI + + FL K G+ H++ +
Sbjct: 402 AVPRNVQPYVVYEEVTNVWINVHDIFYPFPQSEGEDELCFLRANECKTGFCHLYKVTAVL 461
Query: 483 -------SEDTNPRQ------------ITEGSWEVKEILG----VEGESEIVYFQSNLFH 519
SE +P + +T G WEV G V E+++VYFQ
Sbjct: 462 KSQGYDWSEPFSPGEDEFKCPIKEEIALTSGEWEVLARHGSKIWVNEETKLVYFQGTKDT 521
Query: 520 PMGLQLHTASLKDNSATLNLQQTEVLEYSKFTLSTSCKFAIKQYLGPDVPYTYAGDLWQL 579
P+ L+ S + + L T +S ++S + + Y P +++L
Sbjct: 522 PLEHHLYVVSYEAAGEIVRLT-TPGFSHS-CSMSQNFDMFVSHYSSVSTPPCV--HVYKL 577
Query: 580 LNASEDDHSKILLTKNEHIEEAIQMYDYPVTDYKEITLEDYTEINYVEIKPKTFEPEKKY 639
+D K +E A DY + + + KP +P KK+
Sbjct: 578 SGPDDDPLHKQPRFWASMMEAASCPPDYVPPEIFHFHTRSDVRLYGMIYKPHALQPGKKH 637
Query: 640 PLLVYVYGGPGSETFNTKFXXXXXXXXXXXXXX--XVLKIEPRGTGGKGWNFKSWANRNI 697
P +++VYGGP + N F V+ I+ RG+ +G F+ +
Sbjct: 638 PTVLFVYGGPQVQLVNNSFKGIKYLRLNTLASLGYAVVVIDGRGSCQRGLRFEGALKNQM 697
Query: 698 GFWEPRDIINVTKKYIETQKDVIAQDKVAIWGWSYGGFTTLKTLEFDKGSVFKYGVSVAP 757
G E D + + ++ + I +VAI GWSYGGF +L L K VFK ++ AP
Sbjct: 698 GQVEIEDQVEGLQ-FVAEKYGFIDLSRVAIHGWSYGGFLSLMGL-IHKPQVFKVAIAGAP 755
Query: 758 VTDWKYYDSVYSERYLGSPLSSD-AYDKNAKIKDYDSF-KFTKRFLLMHGTADDNVHIQN 815
VT W YD+ Y+ERY+ P ++ Y+ + + R L++HG D+NVH +
Sbjct: 756 VTVWMAYDTGYTERYMDVPENNQHGYEAGSVALHVEKLPNEPNRLLILHGFLDENVHFFH 815
Query: 816 TYELIDNFNLHSVRNYDMHIFPDSDHSI 843
T L+ + + + Y + I+P+ HSI
Sbjct: 816 TNFLVSQL-IRAGKPYQLQIYPNERHSI 842
>CE28837 [O] KOG2281 Dipeptidyl aminopeptidases/acylaminoacyl-peptidases
Length = 927
Score = 114 bits (284), Expect = 9e-25
Identities = 65/245 (26%), Positives = 121/245 (48%), Gaps = 14/245 (5%)
Query: 628 IKPKTFEPEKKYPLLVYVYGGPGSETFNTKFXXXXXXXXXXXXXXXVLKIEPRGTGGKGW 687
++P F+P KKYP+ YVYGGPG + + F V I+ RG+ +G
Sbjct: 678 LRPSNFDPYKKYPVFHYVYGGPGIQIVHNDFSWIQYIRFCRLGYVVVF-IDNRGSAHRGI 736
Query: 688 NFKSWANRNIGFWEPRDIINVTKKYIETQKDVIAQDKVAIWGWSYGGFTTLKTLEFDKGS 747
F+ ++ +G E D + + E + +V + GWSYGG+ L+ + +
Sbjct: 737 EFERHIHKKMGTVEVEDQVEGLQMLAERTGGFMDMSRVVVHGWSYGGYMALQMIA-KHPN 795
Query: 748 VFKYGVSVAPVTDWKYYDSVYSERYLGSPLSSDAYDKNA------KIKDYDSFKFTKRFL 801
+++ ++ V+DW+ YD+ Y+ERY+G PL Y ++ K+ D + R +
Sbjct: 796 IYRAAIAGGAVSDWRLYDTAYTERYMGYPLEEHVYGASSITGLVEKLPDEPN-----RLM 850
Query: 802 LMHGTADDNVHIQNTYELIDNFNLHSVRNYDMHIFPDSDHSIYFHNAQRMVYEKIYFWIK 861
L+HG D+NVH + L+D + + +++ IFP+ H + ++A + ++ ++ +
Sbjct: 851 LVHGLMDENVHFAHLTHLVDEC-IKKGKWHELVIFPNERHGVRNNDASIYLDARMMYFAQ 909
Query: 862 DAFLG 866
A G
Sbjct: 910 QAIQG 914
>CE17153 [O] KOG2281 Dipeptidyl aminopeptidases/acylaminoacyl-peptidases
Length = 931
Score = 114 bits (284), Expect = 9e-25
Identities = 65/245 (26%), Positives = 121/245 (48%), Gaps = 14/245 (5%)
Query: 628 IKPKTFEPEKKYPLLVYVYGGPGSETFNTKFXXXXXXXXXXXXXXXVLKIEPRGTGGKGW 687
++P F+P KKYP+ YVYGGPG + + F V I+ RG+ +G
Sbjct: 682 LRPSNFDPYKKYPVFHYVYGGPGIQIVHNDFSWIQYIRFCRLGYVVVF-IDNRGSAHRGI 740
Query: 688 NFKSWANRNIGFWEPRDIINVTKKYIETQKDVIAQDKVAIWGWSYGGFTTLKTLEFDKGS 747
F+ ++ +G E D + + E + +V + GWSYGG+ L+ + +
Sbjct: 741 EFERHIHKKMGTVEVEDQVEGLQMLAERTGGFMDMSRVVVHGWSYGGYMALQMIA-KHPN 799
Query: 748 VFKYGVSVAPVTDWKYYDSVYSERYLGSPLSSDAYDKNA------KIKDYDSFKFTKRFL 801
+++ ++ V+DW+ YD+ Y+ERY+G PL Y ++ K+ D + R +
Sbjct: 800 IYRAAIAGGAVSDWRLYDTAYTERYMGYPLEEHVYGASSITGLVEKLPDEPN-----RLM 854
Query: 802 LMHGTADDNVHIQNTYELIDNFNLHSVRNYDMHIFPDSDHSIYFHNAQRMVYEKIYFWIK 861
L+HG D+NVH + L+D + + +++ IFP+ H + ++A + ++ ++ +
Sbjct: 855 LVHGLMDENVHFAHLTHLVDEC-IKKGKWHELVIFPNERHGVRNNDASIYLDARMMYFAQ 913
Query: 862 DAFLG 866
A G
Sbjct: 914 QAIQG 918
>Hs18450278 [O] KOG2281 Dipeptidyl aminopeptidases/acylaminoacyl-peptidases
Length = 782
Score = 61.2 bits (147), Expect = 7e-09
Identities = 37/103 (35%), Positives = 57/103 (54%), Gaps = 8/103 (7%)
Query: 748 VFKYG-----VSVAPVTDWKYYDSVYSERYLGSP-LSSDAYDKNAKIKDYDSF-KFTKRF 800
+F YG ++ APVT W +YD+ Y+ERY+G P + Y + + F R
Sbjct: 650 LFIYGGPQVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRL 709
Query: 801 LLMHGTADDNVHIQNTYELIDNFNLHSVRNYDMHIFPDSDHSI 843
LL+HG D+NVH +T L+ +F + + + YD+ I+P HSI
Sbjct: 710 LLLHGFLDENVHFAHTSILL-SFLVRAGKPYDLQIYPQERHSI 751
>7289544 [O] KOG2100 Dipeptidyl aminopeptidase
Length = 184
Score = 56.2 bits (134), Expect = 2e-07
Identities = 34/105 (32%), Positives = 54/105 (51%), Gaps = 2/105 (1%)
Query: 209 LDYAILGSNVIKEYRHSSSGLYWLYNLKTSVLTPVKGKDS-KSPHPRLSYCHFSPSYRYI 267
L Y + NV K ++ S + Y +Y++ TPVK KD+ K RL Y + + I
Sbjct: 68 LKYVLFTHNVKKNFQKSFTAFYTIYDVTNDHHTPVKLKDTLKVQRTRLQYASWLGNTTAI 127
Query: 268 YFVEDNDLHVQSLDDQGDIYRITSDG-SNYVLNGRTDWVYEEELL 311
FV ND+ ++ + RITS G N++ NG DW+Y+ ++
Sbjct: 128 IFVVKNDIFIRQSPLVEEDIRITSSGHENHIYNGVPDWLYQGRVI 172
>CE01231 [O] KOG2100 Dipeptidyl aminopeptidase
Length = 629
Score = 50.8 bits (120), Expect = 9e-06
Identities = 56/218 (25%), Positives = 85/218 (38%), Gaps = 19/218 (8%)
Query: 640 PLLVYVYGGPGSETFNTKFXXXXXXXXXXXXXXXVLKIEPRGTGGKGWNFKSWANRNIGF 699
P+L+ +GGP + N V + RG+ G G F+ +N G
Sbjct: 389 PVLLLGHGGPTAPAQNN---LDLKKQFFTSRGIAVFDVNYRGSTGFGTEFRRMLYKNCGV 445
Query: 700 WEPRDIINVTKKYIETQKDVIAQDKVAIWGWSYGGFTTLKTLEFDKGSVFKYGVSVAPVT 759
+ D++N K +E K + +KV I G S GG+ L L K ++ K VSV V
Sbjct: 446 ADRDDMLNGAKALVEQGK--VDAEKVLITGSSSGGYLILSCLISPK-NIIKAAVSVYGVA 502
Query: 760 DWKYYDS-------VYSERYLGS-PLSSDAYDKNAKIKDYDSFKFTKRFLLMHGTADDNV 811
D D Y+E +G P + Y++ + I D + FL HG D V
Sbjct: 503 DLLALDEDTHKLERCYNEMLIGKYPEQASIYEERSPIYHIDKIRTPIAFL--HGREDTVV 560
Query: 812 HIQNTYELIDNFNLHSVRNYDMHIFPDSDHSIYFHNAQ 849
+ + + + V M +F H F N Q
Sbjct: 561 PMSQSITMYEKIRASGVTTALM-LFDGEGHG--FRNGQ 595
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.317 0.136 0.407
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 54,543,554
Number of Sequences: 60738
Number of extensions: 2451618
Number of successful extensions: 5837
Number of sequences better than 1.0e-05: 24
Number of HSP's better than 0.0 without gapping: 11
Number of HSP's successfully gapped in prelim test: 13
Number of HSP's that attempted gapping in prelim test: 5689
Number of HSP's gapped (non-prelim): 47
length of query: 872
length of database: 30,389,216
effective HSP length: 115
effective length of query: 757
effective length of database: 23,404,346
effective search space: 17717089922
effective search space used: 17717089922
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)