ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIV1812 good O KOG3003 Posttranslational modification, protein turnover, chaperones Molecular chaperone of the GrpE family
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIV1812 625107 625835 243
(243 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YOR232w [O] KOG3003 Molecular chaperone of the GrpE family 294 7e-80
SPBC3B9.19 [O] KOG3003 Molecular chaperone of the GrpE family 157 1e-38
7303294 [O] KOG3003 Molecular chaperone of the GrpE family 135 7e-32
At4g26780 [O] KOG3003 Molecular chaperone of the GrpE family 134 2e-31
Hs18559169 [O] KOG3003 Molecular chaperone of the GrpE family 120 2e-27
CE03057 [O] KOG3003 Molecular chaperone of the GrpE family 120 2e-27
At5g55200 [O] KOG3003 Molecular chaperone of the GrpE family 116 3e-26
Hs17446569 [O] KOG3003 Molecular chaperone of the GrpE family 91 1e-18
At5g17710 [O] KOG3003 Molecular chaperone of the GrpE family 68 1e-11
At1g36390 [O] KOG3003 Molecular chaperone of the GrpE family 59 5e-09
Hs22049603_2 [O] KOG3003 Molecular chaperone of the GrpE family 50 4e-06
>YOR232w [O] KOG3003 Molecular chaperone of the GrpE family
Length = 228
Score = 294 bits (753), Expect = 7e-80
Identities = 144/170 (84%), Positives = 160/170 (93%)
Query: 74 NLTEEQKKIKDLETKLDAKTKEASEFKDRLLRSVADFRNLQEVTKKDIQKAKDFALQKFA 133
+LTEEQ +IK LE++L AKTKEASE KDRLLRSVADFRNLQ+VTKKDIQKAKDFALQKFA
Sbjct: 59 DLTEEQSEIKKLESQLSAKTKEASELKDRLLRSVADFRNLQQVTKKDIQKAKDFALQKFA 118
Query: 134 KDLLESVDNFGHALNAFKPETLEQSQELSDLYTGVKMTRDVFEKTLKKHGIEQLNPIGES 193
KDLLESVDNFGHALNAFK E L++S+E+SDLYTGV+MTRDVFE TL+KHGIE+L+P+GE
Sbjct: 119 KDLLESVDNFGHALNAFKEEDLQKSKEISDLYTGVRMTRDVFENTLRKHGIEKLDPLGEP 178
Query: 194 FDPNKHEATFELPQPDKEPGTVFHVQQIGYTLNDRVIRPAKVGIVKDNEN 243
FDPNKHEATFELPQPDKEPGTVFHVQQ+G+TLNDRVIRPAKVGIVK EN
Sbjct: 179 FDPNKHEATFELPQPDKEPGTVFHVQQLGFTLNDRVIRPAKVGIVKGEEN 228
>SPBC3B9.19 [O] KOG3003 Molecular chaperone of the GrpE family
Length = 223
Score = 157 bits (397), Expect = 1e-38
Identities = 79/172 (45%), Positives = 116/172 (66%), Gaps = 3/172 (1%)
Query: 74 NLTEEQKKIKDLETKLDAKTKEASEFKDRLLRSVADFRNLQEVTKKDIQKAKDFALQKFA 133
++ E Q K+ +L++K +AK KE +E K + +S+AD+RNL+ K+D+++ + FA+QK
Sbjct: 52 DVKELQSKLSELKSKYEAKDKEVAELKGSIRQSLADYRNLENRMKRDMEQTRAFAVQKLT 111
Query: 134 KDLLESVDNFGHALNAFKPE---TLEQSQELSDLYTGVKMTRDVFEKTLKKHGIEQLNPI 190
KDLL+SVDN AL+ E E +++L DLY G+ MT KTL K+G+ + + I
Sbjct: 112 KDLLDSVDNLERALSIVPEEKRNNRESNKDLVDLYEGLAMTESNLMKTLGKYGLVRYDGI 171
Query: 191 GESFDPNKHEATFELPQPDKEPGTVFHVQQIGYTLNDRVIRPAKVGIVKDNE 242
GE FDPN HEA F++P K+P TVFH + G+ LN RVIRPAKVG+VK ++
Sbjct: 172 GEDFDPNIHEAVFQIPVEGKKPNTVFHCESKGFQLNGRVIRPAKVGVVKGDD 223
>7303294 [O] KOG3003 Molecular chaperone of the GrpE family
Length = 213
Score = 135 bits (339), Expect = 7e-32
Identities = 68/164 (41%), Positives = 97/164 (58%)
Query: 76 TEEQKKIKDLETKLDAKTKEASEFKDRLLRSVADFRNLQEVTKKDIQKAKDFALQKFAKD 135
TE +++ L +L A ++ +E D+ RS+AD N++ K I AK F +Q F KD
Sbjct: 49 TESSPEVEKLTKELAAAKEQNAELMDKYKRSLADSENMRNRLNKQISDAKIFGIQSFCKD 108
Query: 136 LLESVDNFGHALNAFKPETLEQSQELSDLYTGVKMTRDVFEKTLKKHGIEQLNPIGESFD 195
LLE D GHA A + L + +L +LY G+ MTR + K+HG+E L+PI + FD
Sbjct: 109 LLEVADTLGHATQAVPKDKLSGNADLKNLYEGLTMTRASLLQVFKRHGLEPLDPINQKFD 168
Query: 196 PNKHEATFELPQPDKEPGTVFHVQQIGYTLNDRVIRPAKVGIVK 239
PN+HEA F+ EP TV V ++GY L++R IRPA VG+ K
Sbjct: 169 PNQHEALFQKEDKTVEPNTVVEVTKLGYKLHERCIRPALVGVSK 212
>At4g26780 [O] KOG3003 Molecular chaperone of the GrpE family
Length = 311
Score = 134 bits (336), Expect = 2e-31
Identities = 70/173 (40%), Positives = 102/173 (58%), Gaps = 9/173 (5%)
Query: 80 KKIKDLETKLDAKTKEASEFKDRLLRSVADFRNLQEVTKKDIQKAKDFALQKFAKDLLES 139
K + + E L K +E + KD++LR+ A+ N+ + T++D + K +A+Q FAK LL+
Sbjct: 130 KLVAEKEELLSEKEEEIKQLKDKVLRTYAEMENVMDRTRRDAENTKKYAVQNFAKSLLDV 189
Query: 140 VDNFGHALNAFKPE--TLEQSQE-------LSDLYTGVKMTRDVFEKTLKKHGIEQLNPI 190
DN G A + K L+ S++ L L GV+MT + KK G+E+ +PI
Sbjct: 190 ADNLGRASSVVKESFSKLDTSEDSAGAAPLLKTLLEGVEMTEKQLAEVFKKFGMEKYDPI 249
Query: 191 GESFDPNKHEATFELPQPDKEPGTVFHVQQIGYTLNDRVIRPAKVGIVKDNEN 243
E FDPN+H A F++P K GTV HV + GYTL DRVIRPA+VG+ + EN
Sbjct: 250 NEPFDPNRHNAVFQVPDASKPEGTVAHVLKSGYTLYDRVIRPAEVGVTQGGEN 302
>Hs18559169 [O] KOG3003 Molecular chaperone of the GrpE family
Length = 217
Score = 120 bits (301), Expect = 2e-27
Identities = 65/163 (39%), Positives = 98/163 (59%), Gaps = 4/163 (2%)
Query: 79 QKKIKDLETKLDAKTKEASEFKDRLLRSVADFRNLQEVTKKDIQKAKDFALQKFAKDLLE 138
+K + + + KL+ + KE E + R++AD NL++ ++K +++AK + +Q F KDLLE
Sbjct: 57 EKTLLEEKVKLEEQLKETVE---KYKRALADTENLRQRSQKLVEEAKLYGIQAFCKDLLE 113
Query: 139 SVDNFGHALNAF-KPETLEQSQELSDLYTGVKMTRDVFEKTLKKHGIEQLNPIGESFDPN 197
D A K E + + L +LY G+ MT +K KHG+ +LNP+G FDP
Sbjct: 114 VADVLEKATQCVPKEEIKDDNPHLKNLYEGLVMTEVQIQKVFTKHGLLKLNPVGAKFDPY 173
Query: 198 KHEATFELPQPDKEPGTVFHVQQIGYTLNDRVIRPAKVGIVKD 240
+HEA F P KEPGTV V ++GY L+ R +RPA VG+VK+
Sbjct: 174 EHEALFHTPVEGKEPGTVALVSKVGYKLHGRTLRPALVGVVKE 216
>CE03057 [O] KOG3003 Molecular chaperone of the GrpE family
Length = 237
Score = 120 bits (300), Expect = 2e-27
Identities = 67/147 (45%), Positives = 92/147 (62%), Gaps = 3/147 (2%)
Query: 95 EASEFKDRLLRSVADFRNLQEVTKKDIQKAKDFALQKFAKDLLESVDNFGHALNAFKPET 154
E+ +FKD+ RS+A+ N++ K AK FA+Q F KDLLE D A+ + KPE
Sbjct: 89 ESLDFKDKYQRSLAETENVRRRGIKQTDDAKVFAIQSFCKDLLEVSDILDIAVKSVKPED 148
Query: 155 LEQS-QELSDLYTGVKMTRDVFEKTLKKHGIEQLNPIGESFDPNKHEATFELPQPD-KEP 212
LE + L DL+ GV MTR V KT KHG+ ++P E FDPN HEA F++P + K+P
Sbjct: 149 LESGGKALKDLFEGVSMTRTVMAKTFAKHGLVTVDPTNEKFDPNLHEAVFQIPSANAKQP 208
Query: 213 -GTVFHVQQIGYTLNDRVIRPAKVGIV 238
G + +IGY+L +R IRPA+VG+V
Sbjct: 209 VGHIEVCTKIGYSLKERPIRPAQVGVV 235
>At5g55200 [O] KOG3003 Molecular chaperone of the GrpE family
Length = 302
Score = 116 bits (290), Expect = 3e-26
Identities = 63/173 (36%), Positives = 100/173 (57%), Gaps = 9/173 (5%)
Query: 80 KKIKDLETKLDAKTKEASEFKDRLLRSVADFRNLQEVTKKDIQKAKDFALQKFAKDLLES 139
K + + E L + K+ E KD+ LR+ A+ +NL + T ++ + AK FA+Q FA LL+
Sbjct: 121 KLVSEKEDLLKVQQKDIMEMKDKFLRTYAEQQNLMDRTNRNAESAKKFAVQNFATSLLDV 180
Query: 140 VDNFGHALNAFKPE--TLEQSQELS-------DLYTGVKMTRDVFEKTLKKHGIEQLNPI 190
DN A + K ++ S++L+ +L GV+MT + +K G+ + +P+
Sbjct: 181 ADNLERASSVVKESFSKIDTSKDLAGATPLLKNLLEGVEMTEKQLAEVFRKAGLVKEDPL 240
Query: 191 GESFDPNKHEATFELPQPDKEPGTVFHVQQIGYTLNDRVIRPAKVGIVKDNEN 243
E F+PN+H A F++P K GT+ HV + GY+L DRVIRPA+VG+ EN
Sbjct: 241 NEPFNPNRHNAVFQVPDASKPKGTIAHVLKSGYSLYDRVIRPAEVGVTCAVEN 293
>Hs17446569 [O] KOG3003 Molecular chaperone of the GrpE family
Length = 225
Score = 91.3 bits (225), Expect = 1e-18
Identities = 51/161 (31%), Positives = 86/161 (52%), Gaps = 3/161 (1%)
Query: 85 LETKLDAKTKEASEFKDRLLRSVADFRNLQEVTKKDIQKAKDFALQKFAKDLLESVDNFG 144
L K KE + R R++AD N++ T++ ++ AK F +Q F KDL+E D
Sbjct: 62 LRVKAVKLEKEVQDLTVRYQRAIADCENIRRRTQRCVEDAKIFGIQSFCKDLVEVADILE 121
Query: 145 HALNAFKPETLEQSQELS--DLYTGVKMTRDVFEKTLKKHGIEQLNPIGESFDPNKHEAT 202
E+ + Q+L+ ++ G+ + + KHG+E+L PIG+ +DP++HE
Sbjct: 122 KTTECISEESEPEDQKLTLEKVFRGLLLLEAKLKSVFAKHGLEKLTPIGDKYDPHEHELI 181
Query: 203 FELPQ-PDKEPGTVFHVQQIGYTLNDRVIRPAKVGIVKDNE 242
+P +PGTV V+Q GY L+ R IR A+V + +++
Sbjct: 182 CHVPAGVGVQPGTVALVRQDGYKLHGRTIRLARVEVAVESQ 222
>At5g17710 [O] KOG3003 Molecular chaperone of the GrpE family
Length = 326
Score = 68.2 bits (165), Expect = 1e-11
Identities = 47/162 (29%), Positives = 82/162 (50%), Gaps = 8/162 (4%)
Query: 80 KKIKD----LETKLDAKTKEASEFKDRLLRSVADFRNLQEVTKKDIQKAKDFALQKFAKD 135
K I+D L K+ + + E S +DRL+R ADF N ++ T+++ A + ++
Sbjct: 139 KSIEDEKFLLADKVASLSNELSVERDRLIRISADFDNFRKRTERERLNLVSNAQGEVVEN 198
Query: 136 LLESVDNFGHALNAFKPETLEQSQELSDLYTGVKMTRDVFEKTLKKHGIEQLNPIGESFD 195
LL +DNF A + K ET E +++++ Y + F + L G+ + +G+ FD
Sbjct: 199 LLAVLDNFERAKSQIKVET-EGEEKVTNSYQSIYKQ---FVEILGSLGVIHVETVGKQFD 254
Query: 196 PNKHEATFELPQPDKEPGTVFHVQQIGYTLNDRVIRPAKVGI 237
P HEA + E G V + G+ L +R++RP+ V +
Sbjct: 255 PMLHEAIMREDSAEYEEGIVLEEYRKGFLLGERLLRPSMVKV 296
>At1g36390 [O] KOG3003 Molecular chaperone of the GrpE family
Length = 399
Score = 59.3 bits (142), Expect = 5e-09
Identities = 47/162 (29%), Positives = 77/162 (47%), Gaps = 10/162 (6%)
Query: 81 KIKDLETKLDAKT-----KEASEFKDRLLRSVADFRNLQEVTKKDIQKAKDFALQKFAKD 135
KI+ + K+D K K ASE K+ +R ADF N ++ KD + A + K
Sbjct: 223 KIEKEKNKMDQKVLSLSMKIASE-KEMKIRLQADFDNTRKKLDKDRLSTESNAKVQILKS 281
Query: 136 LLESVDNFGHALNAFKPETLEQSQELSDLYTGVKMTRDVFEKTLKKHGIEQLNPIGESFD 195
LL +D+F A + +T ++ +++ Y G+ F + L+ + + +G+ FD
Sbjct: 282 LLPIIDSFEKAKLQVRVDT-DKEKKIDTSYQGIYRQ---FVEVLRYLRVSVIATVGKPFD 337
Query: 196 PNKHEATFELPQPDKEPGTVFHVQQIGYTLNDRVIRPAKVGI 237
P HEA + G + G+ L DRV+RPAKV +
Sbjct: 338 PLLHEAISREESEAVKAGIITEELNKGFVLGDRVLRPAKVKV 379
>Hs22049603_2 [O] KOG3003 Molecular chaperone of the GrpE family
Length = 128
Score = 49.7 bits (117), Expect = 4e-06
Identities = 25/83 (30%), Positives = 45/83 (54%), Gaps = 1/83 (1%)
Query: 161 LSDLYTGVKMTRDVFEKTLKKHGIEQLNPIGESFDPNKHEATFELPQP-DKEPGTVFHVQ 219
L ++ G+ + + KHG+E+L+PIG+ +DP +HE + +P TV V+
Sbjct: 43 LEKVFRGLSLLEAKLKNVFAKHGLEKLSPIGDKYDPQEHELICHVTAAVGVQPSTVTLVR 102
Query: 220 QIGYTLNDRVIRPAKVGIVKDNE 242
GY L+ IR A+V + +++
Sbjct: 103 PDGYKLHGCTIRLARVEVAVESQ 125
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.315 0.132 0.360
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,069,320
Number of Sequences: 60738
Number of extensions: 465933
Number of successful extensions: 2039
Number of sequences better than 1.0e-05: 11
Number of HSP's better than 0.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 2020
Number of HSP's gapped (non-prelim): 13
length of query: 243
length of database: 30,389,216
effective HSP length: 103
effective length of query: 140
effective length of database: 24,133,202
effective search space: 3378648280
effective search space used: 3378648280
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)