ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIV1872 good T KOG2210 Signal transduction mechanisms Oxysterol-binding protein
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIV1872 641278 642522 415
(415 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YPL145c [T] KOG2210 Oxysterol-binding protein 546 e-155
YOR237w [T] KOG2210 Oxysterol-binding protein 492 e-139
SPBC1271.12 [T] KOG2210 Oxysterol-binding protein 277 2e-74
SPBC354.07c [T] KOG2210 Oxysterol-binding protein 226 6e-59
7303831 [T] KOG2210 Oxysterol-binding protein 128 2e-29
Hs20070331 [T] KOG2210 Oxysterol-binding protein 127 2e-29
SPCC23B6.01c [T] KOG2210 Oxysterol-binding protein 121 2e-27
Hs19923592 [T] KOG2210 Oxysterol-binding protein 107 3e-23
Hs22035609 [T] KOG2210 Oxysterol-binding protein 105 1e-22
Hs14149740 [T] KOG2210 Oxysterol-binding protein 105 1e-22
CE08539 [T] KOG2210 Oxysterol-binding protein 105 1e-22
YKR003w [T] KOG2210 Oxysterol-binding protein 104 3e-22
Hs19923812 [T] KOG2210 Oxysterol-binding protein 102 8e-22
Hs18079218 [T] KOG2210 Oxysterol-binding protein 100 4e-21
YHR001w [T] KOG2210 Oxysterol-binding protein 97 6e-20
CE06680 [T] KOG2210 Oxysterol-binding protein 91 2e-18
Hs22066714 [T] KOG2210 Oxysterol-binding protein 82 2e-15
7291708 [T] KOG2209 Oxysterol-binding protein 69 1e-11
Hs19718746 [T] KOG2209 Oxysterol-binding protein 67 6e-11
Hs19718741 [T] KOG2209 Oxysterol-binding protein 67 6e-11
At5g57240 [T] KOG2210 Oxysterol-binding protein 66 1e-10
Hs7662298 [T] KOG2209 Oxysterol-binding protein 64 3e-10
Hs21450853 [T] KOG2209 Oxysterol-binding protein 64 3e-10
At4g25860 [T] KOG2210 Oxysterol-binding protein 60 6e-09
YHR073w [I] KOG1737 Oxysterol-binding protein 60 8e-09
YDL019c [I] KOG1737 Oxysterol-binding protein 59 1e-08
At4g25850 [T] KOG2210 Oxysterol-binding protein 59 2e-08
Hs17473098 [T] KOG2210 Oxysterol-binding protein 57 4e-08
CE23653 [T] KOG2209 Oxysterol-binding protein 57 5e-08
YAR044w [I] KOG1737 Oxysterol-binding protein 55 1e-07
SPBC646.08c [T] KOG2210 Oxysterol-binding protein 54 3e-07
SPBC2F12.05c_2 [I] KOG1737 Oxysterol-binding protein 52 1e-06
Hs22035612 [I] KOG1737 Oxysterol-binding protein 50 6e-06
Hs14210532 [I] KOG1737 Oxysterol-binding protein 50 6e-06
>YPL145c [T] KOG2210 Oxysterol-binding protein
Length = 434
Score = 546 bits (1408), Expect = e-155
Identities = 279/437 (63%), Positives = 323/437 (73%), Gaps = 25/437 (5%)
Query: 1 MSQYASSSSWTSFLKSISSFNGDLSSLTAPPFILSPVSLTEYSEYWAEHPDLFLEPSFIT 60
MSQYASSSSWTSFLKSI+SFNGDLSSL+APPFILSP+SLTE+S+YWAEHP+LFLEPSFI
Sbjct: 1 MSQYASSSSWTSFLKSIASFNGDLSSLSAPPFILSPISLTEFSQYWAEHPELFLEPSFIN 60
Query: 61 EP--------DSDGTPPELLRMLAVVKWFISTLKSQYCSRNESMGSEKKPLNPFLGEVFV 112
+ D + PEL RMLAV KWFISTLKSQYCSRNES+GSEKKPLNPFLGE+FV
Sbjct: 61 DDNYKEHCLIDPEVESPELARMLAVTKWFISTLKSQYCSRNESLGSEKKPLNPFLGELFV 120
Query: 113 GKWNNKSNPEFGETVLLSEQVSHHPPITAYTIFNDKNQVSLEGYNQVKASISK-MSLNVK 171
GKW NK +PEFGETVLLSEQVSHHPP+TA++IFNDKN+V L+GYNQ+KAS +K + L VK
Sbjct: 121 GKWENKEHPEFGETVLLSEQVSHHPPVTAFSIFNDKNKVKLQGYNQIKASFTKSLMLTVK 180
Query: 172 QYGHAILNFGKLNEQYLITLPPLHIEGLLAASPFVELEGKSYIQASNGLYCSIEFSGKGY 231
Q+GH +L+ +E YL+T PPLHIEG+L ASPFVELEGKSYIQ+S GL C IEFSG+GY
Sbjct: 181 QFGHTMLDIK--DESYLVTPPPLHIEGILVASPFVELEGKSYIQSSTGLLCVIEFSGRGY 238
Query: 232 FSGKKNSFKARIFKSFNDSNDKHNALYTIAGQWXXXXXXXXXXXXXXETVFYDASKLSVE 291
FSGKKNSFKARI+K DS DK ALYTI+GQW +FYDA+++ E
Sbjct: 239 FSGKKNSFKARIYKDSKDSKDKEKALYTISGQWSGSSKIIKANKKEESRLFYDAARIPAE 298
Query: 292 TLTVKSIEEQHPLESRKAWQLVAAATKSGNFDLIHXXXXXXXXXXXXXXXXXXAKGIDWQ 351
L VK +EEQHPLESRKAW VA A K G+F+LI AKGI WQ
Sbjct: 299 HLNVKPLEEQHPLESRKAWYDVAGAIKLGDFNLIAKTKTELEETQRELRKEEEAKGISWQ 358
Query: 352 RRWFKDYDYS----------EKDPDTFTKLAILANISVKNLPSGTLVSEE---KKDANML 398
RRWFKD+DYS EKD DTF KLA N+S KN PSGTLV ++ K+D + +
Sbjct: 359 RRWFKDFDYSVTPEEGALVPEKD-DTFLKLASALNLSTKNAPSGTLVGDKEDRKEDLSSI 417
Query: 399 HWRFDHESWDKETEIKL 415
HWRF E WD+E EI L
Sbjct: 418 HWRFQRELWDEEKEIVL 434
>YOR237w [T] KOG2210 Oxysterol-binding protein
Length = 434
Score = 492 bits (1267), Expect = e-139
Identities = 257/437 (58%), Positives = 308/437 (69%), Gaps = 25/437 (5%)
Query: 1 MSQYASSSSWTSFLKSISSFNGDLSSLTAPPFILSPVSLTEYSEYWAEHPDLFLEPSFIT 60
MSQ+ASSSSWTSFLKSISSFNGDLSSL+APPFILSP SLTE+S+YWAEHP LFLEPS I
Sbjct: 1 MSQHASSSSWTSFLKSISSFNGDLSSLSAPPFILSPTSLTEFSQYWAEHPALFLEPSLID 60
Query: 61 -EPDSDGTP-------PELLRMLAVVKWFISTLKSQYCSRNESMGSEKKPLNPFLGEVFV 112
E D P E+ +MLAVV+WFISTL+SQYCSR+ESMGSEKKPLNPFLGEVFV
Sbjct: 61 GENYKDHCPFDPNVESKEVAQMLAVVRWFISTLRSQYCSRSESMGSEKKPLNPFLGEVFV 120
Query: 113 GKWNNKSNPEFGETVLLSEQVSHHPPITAYTIFNDKNQVSLEGYNQVKASISK-MSLNVK 171
GKW N +PEFGETVLLSEQVSHHPP+TA++IFN+KN VS++GYNQ+K +K ++L VK
Sbjct: 121 GKWKNDEHPEFGETVLLSEQVSHHPPMTAFSIFNEKNDVSVQGYNQIKTGFTKTLTLTVK 180
Query: 172 QYGHAILNFGKLNEQYLITLPPLHIEGLLAASPFVELEGKSYIQASNGLYCSIEFSGKGY 231
YGH IL +E YLIT PPLHIEG+L ASPFVEL G+S+IQ+SNG+ C IEFSG+GY
Sbjct: 181 PYGHVILKI--KDETYLITTPPLHIEGILVASPFVELGGRSFIQSSNGMLCVIEFSGRGY 238
Query: 232 FSGKKNSFKARIFKSFNDSNDKHNALYTIAGQWXXXXXXXXXXXXXXETVFYDASKLSVE 291
F+GKKNSFKARI++S + + K NALY I+GQW FYD+S+ E
Sbjct: 239 FTGKKNSFKARIYRSPQEHSHKENALYLISGQWSGVSTIIKKDSQVSHQ-FYDSSETPTE 297
Query: 292 TLTVKSIEEQHPLESRKAWQLVAAATKSGNFDLIHXXXXXXXXXXXXXXXXXXAKGIDWQ 351
L VK IEEQHPLESR+AW+ VA A + GN +I KG++WQ
Sbjct: 298 HLLVKPIEEQHPLESRRAWKDVAEAIRQGNISMIKKTKEELENKQRALREQERVKGVEWQ 357
Query: 352 RRWFKDYDYSEK----------DPDTFTKLAILANISVKNLPSGTLV--SEEKKD-ANML 398
RRWFK DY + + D F KLA +SVKN+PSGTL+ ++KKD + L
Sbjct: 358 RRWFKQVDYMNENTSNDVEKASEDDAFRKLASKLQLSVKNVPSGTLIGGKDDKKDVSTAL 417
Query: 399 HWRFDHESWDKETEIKL 415
HWRFD W +E EI +
Sbjct: 418 HWRFDKNLWMRENEITI 434
>SPBC1271.12 [T] KOG2210 Oxysterol-binding protein
Length = 388
Score = 277 bits (709), Expect = 2e-74
Identities = 160/320 (50%), Positives = 197/320 (61%), Gaps = 19/320 (5%)
Query: 6 SSSSWTSFLKSISSFNGDLSSLTAPPFILSPVSLTEYSEYWAEHPDLFLEPSFITEPDSD 65
+ S+W SFLKSI++F+GDLSSLTAP FILS SL EYS YWAEHP+LF I+ P +
Sbjct: 23 TKSTWLSFLKSIATFSGDLSSLTAPSFILSSTSLIEYSAYWAEHPELF-----ISLPRGE 77
Query: 66 GTPPELLRMLAVVKWFISTLKSQYCSRNESMGSEKKPLNPFLGEVFVGKWNNKSNPEFGE 125
TP E R L V KWF STLK+QY +RNE GSEKKPLNP LGE+F GKWN + GE
Sbjct: 78 -TPLE--RQLLVTKWFASTLKNQYAARNERYGSEKKPLNPILGELFTGKWNT----DIGE 130
Query: 126 -TVLLSEQVSHHPPITAYTIFNDKNQVSLEGYNQVKASISKMSLNVKQYGHAILNFGKLN 184
T L SEQVSHHPPITAY I+N K V LEGYN K+ S ++VKQ GHA L N
Sbjct: 131 DTELTSEQVSHHPPITAYHIYNKKAGVRLEGYNGHKSGFSGPQIHVKQIGHARLILEPHN 190
Query: 185 EQYLITLPPLHIEGLLAASPFVELEGKSYIQASNGLYCSIEFSGKGYFSGKKNSFKARIF 244
E Y IT P + +EGL SP++EL KSYI +++G +IE+SGKGYF+GKKN+FKA I
Sbjct: 191 EVYYITFPLVTLEGLWYGSPYIELGKKSYIISTSGYLTTIEYSGKGYFTGKKNTFKATIV 250
Query: 245 KSFNDSNDKHNALYTIAGQWXXXXXXXXXXXXXXET--VFYDASKLSVETLTVKSIEEQH 302
++ K +Y I G W F D ++V IEEQ
Sbjct: 251 ----NAKTKSEPIYRIEGSWTGMLKYCTFEDQKRSAWEDFLDCGNYKPVNISVAPIEEQG 306
Query: 303 PLESRKAWQLVAAATKSGNF 322
ESR+ W+ A A +G++
Sbjct: 307 EYESRRVWKNFAVALDAGDY 326
>SPBC354.07c [T] KOG2210 Oxysterol-binding protein
Length = 399
Score = 226 bits (575), Expect = 6e-59
Identities = 133/352 (37%), Positives = 191/352 (53%), Gaps = 24/352 (6%)
Query: 22 GDLSSLTAPPFILSPVSLTEYSEYWAEHPDLFLEPSFITEPDSDGTPPELLRMLAVVKWF 81
GDLS+L+AP FILS SL EY YW E P+LF+ + + P TP E RMLAV+KW+
Sbjct: 38 GDLSTLSAPSFILSGTSLLEYMSYWFEFPELFV--TIVDFP----TPKE--RMLAVLKWY 89
Query: 82 ISTLKSQYCSRNESMGSEKKPLNPFLGEVFVGKWNNKSNPEFGETVLLSEQVSHHPPITA 141
I+ L +Y SRN++ G+EKKPLNP LGE+F G W++ G+ L +EQVSHH P +A
Sbjct: 90 ITGLSREYASRNKNYGTEKKPLNPILGELFYGSWDSSK----GKVELTAEQVSHHGPESA 145
Query: 142 YTIFNDKNQVSLEGYNQVKASISKMSLNVKQYGHAILNFGKLNEQYLITLPPLHIEGLLA 201
+ + ++++ +N+ ++ S ++ V Q G ++ K NE Y ITLP + +EGL
Sbjct: 146 AHVVCKEAGITVDTHNKYRSGFSGRTVYVNQLGQLRVHLEKYNETYYITLPNISLEGLWF 205
Query: 202 ASPFVELEGKSYIQASNGLYCSIEFSGKGYFSGKKNSFKARIFKSFNDSNDKHNALYTIA 261
+P++EL G +YI ++ I++SG+GYF G KNSFKA IF+ D + Y +
Sbjct: 206 MAPYIELYGSTYIVSNTNYITKIDYSGRGYFRGTKNSFKATIFEKNEDPD------YIVE 259
Query: 262 GQWXXXXXXXXXXXXXXETVFY-DASKLSVETLTVKSIEEQHPLESRKAWQLVAAATKSG 320
G W T+F+ L +TVK E ESR W+ V+AA SG
Sbjct: 260 GVW--TGESKLTIPSLKSTIFFLSIPSLEATPITVKPESEMGDWESRNVWKEVSAALASG 317
Query: 321 NFDLIHXXXXXXXXXXXXXXXXXXAKGIDWQRRWFKDYDYSEKDPDTFTKLA 372
N+D++ A+G W RR+FK + E D D LA
Sbjct: 318 NYDIVSSKKSTIEQSQRDMRKKEEAEGAVWARRYFK---WEEHDSDARNALA 366
>7303831 [T] KOG2210 Oxysterol-binding protein
Length = 764
Score = 128 bits (321), Expect = 2e-29
Identities = 93/339 (27%), Positives = 159/339 (46%), Gaps = 38/339 (11%)
Query: 1 MSQYASSSSWTSFLKSISSFNGDLSSLTAPPFILSPVSLTE-YSEYWAEHPDLFLEPSFI 59
+S A S T L + DL+ + P FIL SL E Y++Y+A HPDLF++ S +
Sbjct: 390 LSMEAHGSMITHLLSQVK-IGMDLTKVVLPTFILERRSLLEMYADYFA-HPDLFIKISDL 447
Query: 60 TEPDSDGTPPELLRMLAVVKWFISTLKSQYCSRNESMGSEKKPLNPFLGEVFVGKWNNKS 119
+P R++ V +W++S + + R ++ KKP NP LGEVF W+
Sbjct: 448 DDPRD--------RIVQVCRWYMS---AYHAGRKSAVA--KKPYNPILGEVFQCHWDIPG 494
Query: 120 NPEFGETV--------------LLSEQVSHHPPITAYTIFNDKNQVSLEGYNQVKASISK 165
+ + V L+EQVSHHPPI+A+ + +++ + K+
Sbjct: 495 ISQDAQEVRDGPVPWCRRDQLTFLAEQVSHHPPISAFYAEHYNKKITFAAHVWTKSKFLG 554
Query: 166 MSLNVKQYGHAILNFGKLNEQYLITLPPLHIEGLLAASPFVELEGKSYIQA-SNGLYCSI 224
+S+ V G ++ +E+Y++T P + +L P++EL G I+ +G Y ++
Sbjct: 555 LSIGVHNIGEGVVTLVDRSEEYIVTFPNGYGRSILTV-PWIELGGSVEIKCPQSGYYANV 613
Query: 225 EFSGKGYFSGKKNSFKARIFKSFNDSNDKHNALYTIAGQWXXXXXXXXXXXXXXETVFYD 284
EF K ++ GK+N A ++ + + +I G+W E VF D
Sbjct: 614 EFLTKPFYGGKRNRVSAEVY-----APSEKKPFVSITGEWSGLMEAKWHDKNKTE-VFVD 667
Query: 285 ASKLSVETLTVKSIEEQHPLESRKAWQLVAAATKSGNFD 323
+++ + V+ I EQ ESR+ W+ V A K + +
Sbjct: 668 VNRIPIFKKQVRPIVEQDEYESRRVWKEVTAGLKFNDIE 706
>Hs20070331 [T] KOG2210 Oxysterol-binding protein
Length = 736
Score = 127 bits (320), Expect = 2e-29
Identities = 103/352 (29%), Positives = 153/352 (43%), Gaps = 39/352 (11%)
Query: 23 DLSSLTAPPFILSPVSLTE-YSEYWAEHPDLFLEPSFITEPDSDGTPPELLRMLAVVKWF 81
DL+ + P FIL SL E Y++++A HPDLF+ S +P RM+ VVKW+
Sbjct: 387 DLTKVVLPTFILERRSLLEMYADFFA-HPDLFVSISDQKDPKD--------RMVQVVKWY 437
Query: 82 ISTLKSQYCSRNESMGSEKKPLNPFLGEVFVGKW----NNKSNPEF-----------GET 126
+S + R S+ KKP NP LGE+F W + + N E
Sbjct: 438 LSAF---HAGRKGSVA--KKPYNPILGEIFQCHWTLPNDTEENTELVSEGPVPWVSKNSV 492
Query: 127 VLLSEQVSHHPPITAYTIFNDKNQVSLEGYNQVKASISKMSLNVKQYGHAILNFGKLNEQ 186
++EQVSHHPPI+A+ ++ + K+ MS+ V G ++ +E
Sbjct: 493 TFVAEQVSHHPPISAFYAECFNKKIQFNAHIWTKSKFLGMSIGVHNIGQGCVSCLDYDEH 552
Query: 187 YLITLPPLHIEGLLAASPFVELEGKSYIQAS-NGLYCSIEFSGKGYFSGKKNSFKARIFK 245
Y++T P + +L P+VEL G+ I S G +I F K ++ GKK+ A IF
Sbjct: 553 YILTFPNGYGRSILTV-PWVELGGECNINCSKTGYSANIIFHTKPFYGGKKHRITAEIF- 610
Query: 246 SFNDSNDKHNALYTIAGQWXXXXXXXXXXXXXXETVFYDASKLSVETLTVKSIEEQHPLE 305
NDK + +I G+W TVF D KL + V+ +E+Q+ E
Sbjct: 611 ---SPNDK-KSFCSIEGEW--NGVMYAKYATGENTVFVDTKKLPIIKKKVRKLEDQNEYE 664
Query: 306 SRKAWQLVAAATKSGNFDLIHXXXXXXXXXXXXXXXXXXAKGIDWQRRWFKD 357
SR W+ V K + D K I W+ R F +
Sbjct: 665 SRSLWKDVTFNLKIRDIDAATEAKHRLEERQRAEARERKEKEIQWETRLFHE 716
>SPCC23B6.01c [T] KOG2210 Oxysterol-binding protein
Length = 489
Score = 121 bits (303), Expect = 2e-27
Identities = 93/345 (26%), Positives = 145/345 (41%), Gaps = 30/345 (8%)
Query: 21 NGDLSSLTAPPFILSPVSLTEYSEYWAEHPDLFLEPSFITEPDSDGTPPELLRMLAVVKW 80
N DLS +T P F+L P S+ E + HPDL L +P+ +R L VV++
Sbjct: 41 NMDLSKVTFPTFVLEPKSMLERITNFMSHPDLLLNVQKTADPE--------MRFLDVVRF 92
Query: 81 FISTLKSQYCSRNESMGSEKKPLNPFLGEVFVGKW----NNKSNPEF----GETVLLSEQ 132
++S + KKPLNP LGE F G W +N +P G V +EQ
Sbjct: 93 YMSGWHIR-------PRGVKKPLNPILGETFTGFWKFPPSNSKDPNLQKLHGIAVYAAEQ 145
Query: 133 VSHHPPITAYTIFNDKNQVSLEGYNQVKASISKMSLNVKQYGHAILNFGKLNEQYLITLP 192
V HHPPI+AY + +V ++G + ++ S G A + L+E+YLIT P
Sbjct: 146 VCHHPPISAYFYLCPEYKVRIDGVVKPRSRFLGNSAASIMEGIASIKLQDLDEEYLITQP 205
Query: 193 PLHIEGLLAASPFVELEGKSYIQA-SNGLYCSIEFSGKGYFSGKKNSFKARIFKSFNDSN 251
++ G+L +EL ++ L IEF KG+ SG NS ++ +
Sbjct: 206 NVYARGILFGKMRLELGDHVTVRCPKTDLQADIEFKVKGFISGTYNSIAGKVKRV----- 260
Query: 252 DKHNALYTIAGQWXXXXXXXXXXXXXXETVFYDASKLSVETLTVKSIEEQHPLESRKAWQ 311
LY I+G+W + D SK V ++ + +EEQ ES++ W
Sbjct: 261 STGEVLYKISGKWDSEMSVESVKTGETRPLL-DVSKHDVYLVSARPLEEQGERESQRLWY 319
Query: 312 LVAAATKSGNFDLIHXXXXXXXXXXXXXXXXXXAKGIDWQRRWFK 356
A + + + + W+ ++FK
Sbjct: 320 KTCQAVIARDQTTATETKSAIEDRQREEAKQREIENVQWKPKYFK 364
>Hs19923592 [T] KOG2210 Oxysterol-binding protein
Length = 747
Score = 107 bits (267), Expect = 3e-23
Identities = 91/368 (24%), Positives = 147/368 (39%), Gaps = 61/368 (16%)
Query: 23 DLSSLTAPPFILSPVSLTEYSEYWAEHPDLFLEPSFITEPDSDGTPPELLRMLAVVKWFI 82
DL+ + P FIL SL E + HPDLF+ + +G E RM+ V++++
Sbjct: 382 DLTRVVLPTFILEKRSLLEMYADFMSHPDLFIAIT-------NGATAED-RMIRFVEYYL 433
Query: 83 STLKSQYCSRNESMGSEKKPLNPFLGEVFVGKWNNKSN-------------------PEF 123
++ KKP NP +GE F W + P
Sbjct: 434 TSFHE-----GRKGAIAKKPYNPIIGETFHCSWKMPKSEVASSVFSSSSTQGVTNHAPLS 488
Query: 124 GETV-----------LLSEQVSHHPPITAYTIFNDKNQVSLEGYNQVKASISKMSLNVKQ 172
GE++ ++EQVSHHPP++ + + ++ + + K+ MS+ V
Sbjct: 489 GESLTQVGSDCYTVRFVAEQVSHHPPVSGFYAECTERKMCVNAHVWTKSKFLGMSIGVTM 548
Query: 173 YGHAILNFGKLNEQYLITLPPLHIEGLLAASPFVELEGKSYIQ-ASNGLYCSIEFSGKGY 231
G IL+ + E+Y +LP + +L P+VEL GK + A G SI F K +
Sbjct: 549 VGEGILSLLEHGEEYTFSLPCAYARSILTV-PWVELGGKVSVNCAKTGYSASITFHTKPF 607
Query: 232 FSGKKNSFKARIFKSFNDSNDKHNALYTIA----GQWXXXXXXXXXXXXXXETVFYDASK 287
+ GK + A + KHN T+ G+W ET + D +K
Sbjct: 608 YGGKLHRVTAEV---------KHNITNTVVCRVQGEW---NSVLEFTYSNGETKYVDLTK 655
Query: 288 LSVETLTVKSIEEQHPLESRKAWQLVAAATKSGNFDLIHXXXXXXXXXXXXXXXXXXAKG 347
L+V V+ +E+Q P ESR+ W+ V + + D G
Sbjct: 656 LAVTKKRVRPLEKQDPFESRRLWKNVTDSLRESEIDKATEHKHTLEERQRTEERHRTETG 715
Query: 348 IDWQRRWF 355
W+ ++F
Sbjct: 716 TPWKTKYF 723
>Hs22035609 [T] KOG2210 Oxysterol-binding protein
Length = 811
Score = 105 bits (263), Expect = 1e-22
Identities = 92/327 (28%), Positives = 140/327 (42%), Gaps = 33/327 (10%)
Query: 1 MSQYASSSSWTSFLKSISSFNGDLSSLTAPPFILSPVS-LTEYSEYWAEHPDLFLEPSFI 59
+S+ S WT LK + DLS + P F+L P S L + S+Y+ H DL +
Sbjct: 295 VSEENKSLMWT-LLKQLRP-GMDLSRVVLPTFVLEPRSFLNKLSDYYY-HADLLSRAAVE 351
Query: 60 TEPDSDGTPPELLRMLAVVKWFISTLKSQYCSRNESMGSEKKPLNPFLGEVFVGKWNNKS 119
+ S RM V++W++S + KKP NP LGE F W +
Sbjct: 352 EDAYS--------RMKLVLRWYLSGFYKK-------PKGIKKPYNPILGETFRCCWFHPQ 396
Query: 120 NPEFGETVLLSEQVSHHPPITAYTIFNDKNQVSLEGYNQVKASISKMSLNVKQYGHAILN 179
T ++EQVSHHPP++A+ + N K+ + G K+ SL+ G A L
Sbjct: 397 TDS--RTFYIAEQVSHHPPVSAFHVSNRKDGFCISGSITAKSRFYGNSLSALLDGKATLT 454
Query: 180 FGKLNEQYLITLPPLHIEGLLAASPFVELEGKSYIQ-ASNGLYCSIEFSGKGYFSGKK-- 236
F E Y +T+P H +G+L + +EL GK I+ A N +EF K +F G
Sbjct: 455 FLNRAEDYTLTMPYAHCKGILYGTMTLELGGKVTIECAKNNFQAQLEFKLKPFFGGSTSI 514
Query: 237 NSFKARIFKSFNDSNDKHNALYTIAGQWXXXXXXXXXXXXXXETVFYDASKLSVETLTVK 296
N +I L +++G W + + ++ + L
Sbjct: 515 NQISGKI-------TSGEEVLASLSGHWDRDVFIKEEGSGSSALFWTPSGEVRRQRLRQH 567
Query: 297 SI--EEQHPLESRKAWQLVAAATKSGN 321
++ EEQ LES + WQ V A G+
Sbjct: 568 TVPLEEQTELESERLWQHVTRAISKGD 594
>Hs14149740 [T] KOG2210 Oxysterol-binding protein
Length = 879
Score = 105 bits (263), Expect = 1e-22
Identities = 92/327 (28%), Positives = 140/327 (42%), Gaps = 33/327 (10%)
Query: 1 MSQYASSSSWTSFLKSISSFNGDLSSLTAPPFILSPVS-LTEYSEYWAEHPDLFLEPSFI 59
+S+ S WT LK + DLS + P F+L P S L + S+Y+ H DL +
Sbjct: 363 VSEENKSLMWT-LLKQLRP-GMDLSRVVLPTFVLEPRSFLNKLSDYYY-HADLLSRAAVE 419
Query: 60 TEPDSDGTPPELLRMLAVVKWFISTLKSQYCSRNESMGSEKKPLNPFLGEVFVGKWNNKS 119
+ S RM V++W++S + KKP NP LGE F W +
Sbjct: 420 EDAYS--------RMKLVLRWYLSGFYKK-------PKGIKKPYNPILGETFRCCWFHPQ 464
Query: 120 NPEFGETVLLSEQVSHHPPITAYTIFNDKNQVSLEGYNQVKASISKMSLNVKQYGHAILN 179
T ++EQVSHHPP++A+ + N K+ + G K+ SL+ G A L
Sbjct: 465 TDS--RTFYIAEQVSHHPPVSAFHVSNRKDGFCISGSITAKSRFYGNSLSALLDGKATLT 522
Query: 180 FGKLNEQYLITLPPLHIEGLLAASPFVELEGKSYIQ-ASNGLYCSIEFSGKGYFSGKK-- 236
F E Y +T+P H +G+L + +EL GK I+ A N +EF K +F G
Sbjct: 523 FLNRAEDYTLTMPYAHCKGILYGTMTLELGGKVTIECAKNNFQAQLEFKLKPFFGGSTSI 582
Query: 237 NSFKARIFKSFNDSNDKHNALYTIAGQWXXXXXXXXXXXXXXETVFYDASKLSVETLTVK 296
N +I L +++G W + + ++ + L
Sbjct: 583 NQISGKI-------TSGEEVLASLSGHWDRDVFIKEEGSGSSALFWTPSGEVRRQRLRQH 635
Query: 297 SI--EEQHPLESRKAWQLVAAATKSGN 321
++ EEQ LES + WQ V A G+
Sbjct: 636 TVPLEEQTELESERLWQHVTRAISKGD 662
>CE08539 [T] KOG2210 Oxysterol-binding protein
Length = 676
Score = 105 bits (263), Expect = 1e-22
Identities = 96/322 (29%), Positives = 146/322 (44%), Gaps = 43/322 (13%)
Query: 14 LKSISSFNGDLSSLTAPPFILSPVSLTE-YSEYWAEHPDLFLEPSFITEPDSDGTPPELL 72
L S S DL+ +T P FIL SL E Y++++A HPDLF+ ++G
Sbjct: 319 LLSQVSVGMDLTKVTLPTFILERRSLLEMYADFFA-HPDLFIA--------TNGNDSAEK 369
Query: 73 RMLAVVKWFISTLKSQYCSRNESMGSEKKPLNPFLGEVFVGKWN----------NKSNPE 122
RM+AVV+++ L S Y +R G KKP N LGE F +++ +S P
Sbjct: 370 RMIAVVRYY---LNSFYAARKS--GVAKKPYNAILGETFRCRYSVPNSSLSGKKTESGPW 424
Query: 123 FG----ETVLLSEQVSHHPPITAYTIFNDKNQVSLEGYNQVKASISKMSLNVKQYGHAIL 178
G + ++EQVSHHPPI+A+ +S + K+S +S+ V G IL
Sbjct: 425 PGSDEKQLTFIAEQVSHHPPISAFYAEMPSEGISFNAHIYTKSSFLGLSIGVASIGEGIL 484
Query: 179 ---NFGKLNEQYLITLPPLHIEGLLAASPFVELEGKSYIQA-SNGLYCSIEFSGKGYFSG 234
N+G +EQY IT P + ++ ++P+ E GK ++ G IEF K +F G
Sbjct: 485 TLHNYG--DEQYTITFPSGYGRSIM-STPWFEFGGKVKVECEKTGYRADIEFLTKPFFGG 541
Query: 235 KKNSFKARIFKSFNDSNDKHNALYTIAGQWXXXXXXXXXXXXXXETVFYDASKLSVETLT 294
K + + I + + + T+ G+W E VF D
Sbjct: 542 KPHRIQGSICR-----DGAKKPVLTLRGEW--NGTMYAKTQNGEEYVFVDVKAKPEVKKE 594
Query: 295 VKSIEEQHPLESRKAWQLVAAA 316
+ +Q ESR+ W+ V AA
Sbjct: 595 CVPVMQQGKRESRRLWRHVTAA 616
>YKR003w [T] KOG2210 Oxysterol-binding protein
Length = 448
Score = 104 bits (259), Expect = 3e-22
Identities = 86/301 (28%), Positives = 130/301 (42%), Gaps = 32/301 (10%)
Query: 23 DLSSLTAPPFILSPVSLTEYSEYWAEHPDLFLEPSFITEPDSDGTPPELLRMLAVVKWFI 82
DL+ +T P FIL S+ E + P+ L+ +P L R L V+KW++
Sbjct: 63 DLTRITLPTFILEKKSMLERVTNQLQFPEFLLQAHSEKDP--------LKRFLYVMKWYL 114
Query: 83 STLKSQYCSRNESMGSEKKPLNPFLGEVFVGKWNNKSNPEFGETVLLSEQVSHHPPITAY 142
+ + + + KKPLNP LGE F W+ P + +SEQ SHHPP AY
Sbjct: 115 A-------GWHIAPKAVKKPLNPVLGEYFTAYWDL---PNKQQAYYISEQTSHHPPECAY 164
Query: 143 TIFNDKNQVSLEGYNQVKASISKMSLNVKQYGHAILNFGKLN------EQYLITLPPLHI 196
++ + ++G K+ S G +L F + E+Y++T P +++
Sbjct: 165 FYMIPESSIRVDGVVIPKSRFLGNSSAAMMDGSTVLQFLDIKDGNGKPEKYVLTQPNVYV 224
Query: 197 EGLLAASPFVELEGKSYIQASNGLYCSIEFSGKGYFSGKKNSFKARIFKSFNDSNDKHNA 256
G+L +EL G I S IEF KGY G ++ + + K ++ NA
Sbjct: 225 RGILFGKMRIEL-GDHMIIKSPNFQADIEFKTKGYVFGTYDAIEGTV-KDYDG-----NA 277
Query: 257 LYTIAGQWXXXXXXXXXXX-XXXETVFYDASKLSVETLTVKSIEEQHPLESRKAWQLVAA 315
Y I+G+W VF D K S V+ + EQ ESRK W+ V
Sbjct: 278 YYEISGKWNDVMYLKDLKQPRSSPKVFLDTHKESPLRPKVRPLSEQGEYESRKLWKKVTD 337
Query: 316 A 316
A
Sbjct: 338 A 338
>Hs19923812 [T] KOG2210 Oxysterol-binding protein
Length = 764
Score = 102 bits (255), Expect = 8e-22
Identities = 88/330 (26%), Positives = 141/330 (42%), Gaps = 55/330 (16%)
Query: 23 DLSSLTAPPFILSPVSLTEYSEYWAEHPDLFLEPSFITEPDSDGTPPELLRMLAVVKWFI 82
DL+ + P FIL SL E + HPDL L + + TP E R++ V++++
Sbjct: 412 DLTKVVLPTFILEKRSLLEMYADFMAHPDLLLAIT------AGATPEE--RVICFVEYYL 463
Query: 83 STLKSQYCSRNESMGSEKKPLNPFLGEVFVGKWN------------NKSNPEFGETVL-- 128
+ R ++ KKP NP +GE F W ++S E +
Sbjct: 464 TAFHE---GRKGALA--KKPYNPIIGETFHCSWEVPKDRVKPKRTASRSPASCHEHPMAD 518
Query: 129 ----------LSEQVSHHPPITAYTIFNDKNQVSLEGYNQVKASISKMSLNVKQYGHAIL 178
++EQVSHHPPI+ + ++ ++ + + K+ MS+ V G +L
Sbjct: 519 DPSKSYKLRFVAEQVSHHPPISCFYCECEEKRLCVNTHVWTKSKFMGMSVGVSMIGEGVL 578
Query: 179 NFGKLNEQYLITLPPLHIEGLLAASPFVELEGKSYIQ-ASNGLYCSIEFSGKGYFSGKKN 237
+ E+Y+ TLP + +L P+VEL GK I A G ++ F K ++ GK +
Sbjct: 579 RLLEHGEEYVFTLPSAYARSILTI-PWVELGGKVSINCAKTGYSATVIFHTKPFYGGKVH 637
Query: 238 SFKARIFKSFNDSNDKHNALYTIA----GQWXXXXXXXXXXXXXXETVFYDASKLSVETL 293
A + KHN TI G+W ET D + L V
Sbjct: 638 RVTAEV---------KHNPTNTIVCKAHGEW---NGTLEFTYNNGETKVIDTTTLPVYPK 685
Query: 294 TVKSIEEQHPLESRKAWQLVAAATKSGNFD 323
++ +E+Q P+ESR W+ V + G+ D
Sbjct: 686 KIRPLEKQGPMESRNLWREVTRYLRLGDID 715
>Hs18079218 [T] KOG2210 Oxysterol-binding protein
Length = 889
Score = 100 bits (249), Expect = 4e-21
Identities = 98/326 (30%), Positives = 140/326 (42%), Gaps = 41/326 (12%)
Query: 1 MSQYASSSSWTSFLKSISSFNGDLSSLTAPPFILSPVSLTEYSEYWAEHPDLFLEPSFIT 60
+S+ S WT LK + DLS + P FIL P S + + H D E +
Sbjct: 399 VSEENKSLIWT-LLKQVRP-GMDLSKVVLPTFILEPRSFLDKLSDYYYHADFLSEAALEE 456
Query: 61 EPDSDGTPPELLRMLAVVKWFISTLKSQYCSRNESMGSEKKPLNPFLGEVFVGKW-NNKS 119
P R+ VVKW++S + + + + KKP NP LGE F W + ++
Sbjct: 457 NP--------YFRLKKVVKWYLSG----FYKKPKGL---KKPYNPILGETFRCLWIHPRT 501
Query: 120 NPEFGETVLLSEQVSHHPPITAYTIFNDKNQVSLEGYNQVKASISKMSLNVKQYGHAILN 179
N +T ++EQVSHHPPI+A+ + N K+ L G K+ SL+ G A L
Sbjct: 502 N---SKTFYIAEQVSHHPPISAFYVSNRKDGFCLSGSILAKSKFYGNSLSAILEGEARLT 558
Query: 180 FGKLNEQYLITLPPLHIEGLLAASPFVELEGKSYIQASNGLYCSI-EFSGKGYFSG---- 234
F E Y++T+P H +G+L + +EL G I Y +I EF K +
Sbjct: 559 FLNRGEDYVMTMPYAHCKGILYGTMTLELGGTVNITCQKTGYSAILEFKLKPFLGSSDCV 618
Query: 235 KKNSFKARIFKSFNDSNDKHNALYTIAGQWXXXXXXXXXXXXXXETVFY----DASKLSV 290
+ S K ++ K L T+ G W E VF+ D + +
Sbjct: 619 NQISGKLKLGK---------EVLATLEGHWDSEVFITDKKTDNSE-VFWNPTPDIKQWRL 668
Query: 291 ETLTVKSIEEQHPLESRKAWQLVAAA 316
TVK EEQ ES K WQ V A
Sbjct: 669 IRHTVK-FEEQGDFESEKLWQRVTRA 693
>YHR001w [T] KOG2210 Oxysterol-binding protein
Length = 437
Score = 96.7 bits (239), Expect = 6e-20
Identities = 94/377 (24%), Positives = 153/377 (39%), Gaps = 42/377 (11%)
Query: 23 DLSSLTAPPFILSPVSLTEYSEYWAEHPDLFLEPSFITEPDSDGTPPELLRMLAVVKWFI 82
DLS +T P FIL S+ E + PD+ LE + DG L R + VV W++
Sbjct: 63 DLSRITLPTFILEKKSMLERITNQLQFPDVLLE----AHSNKDG----LQRFVKVVAWYL 114
Query: 83 STLKSQYCSRNESMGSEKKPLNPFLGEVFVGKWNNKSNPEFGETVLLSEQVSHHPPITAY 142
+ + + KKPLNP LGE F W+ P + ++EQ SHHPP +AY
Sbjct: 115 A-------GWHIGPRAVKKPLNPILGEHFTAYWDL---PNKQQAFYIAEQTSHHPPESAY 164
Query: 143 TIFNDKNQVSLEGYNQVKASISKMSLNVKQYGHAILNFGKLN------EQYLITLPPLHI 196
++ + ++G K+ S G +L F + E+Y ++ P ++
Sbjct: 165 FYMIPESNIRVDGVVVPKSKFLGNSSAAMMEGLTVLQFLDIKDANGKPEKYTLSQPNVYA 224
Query: 197 EGLLAASPFVELEGKSYIQASNGLYCSIEFSGKGYFSGKKNSFKARIFKSFNDSNDKHNA 256
G+L +EL G + IEF KG+ SG ++ + I D + K
Sbjct: 225 RGILFGKMRIEL-GDHMVIMGPKYQVDIEFKTKGFISGTYDAIEGTI----KDYDGKE-- 277
Query: 257 LYTIAGQW-XXXXXXXXXXXXXXETVFYDASKLSVETLTVKSIEEQHPLESRKAWQLVAA 315
Y I+G+W +TV +D + V+ +EEQ ESR+ W+ V
Sbjct: 278 YYQISGKWNDIMYIKDLREKSSKKTVLFDTHQHFPLAPKVRPLEEQGEYESRRLWKKVTD 337
Query: 316 ATKSGNFDLIHXXXXXXXXXXXXXXXXXXAKGIDWQRRWFKDYDYSEKDPDTFTKLAILA 375
A + ++ G+++ + F+ + E D D +
Sbjct: 338 ALAVRDHEVATEEKFQIENRQRELAKKRAEDGVEFHSKLFRRAEPGE-DLDYYI------ 390
Query: 376 NISVKNLPSGTLVSEEK 392
K++P GT EE+
Sbjct: 391 ---YKHIPEGTDKHEEQ 404
>CE06680 [T] KOG2210 Oxysterol-binding protein
Length = 751
Score = 91.3 bits (225), Expect = 2e-18
Identities = 68/222 (30%), Positives = 104/222 (46%), Gaps = 19/222 (8%)
Query: 23 DLSSLTAPPFILSPVSLTEYSEYWAEHPDLFLEPSFITEPDSDGTPPELLRMLAVVKWFI 82
DLS + P FIL P S E + H DL E + EPD R++ V K+F+
Sbjct: 242 DLSKVVLPTFILEPRSFLEKLADYYYHADLISEA--VAEPDP------FQRIVKVTKFFL 293
Query: 83 STLKSQYCSRNESMGSEKKPLNPFLGEVFVGKWNNKSNPEFGETVLLSEQVSHHPPITAY 142
S + + + + KKP NP LGE F KW + P+ T ++EQVSHHPP+++
Sbjct: 294 SG----FYKKPKGL---KKPYNPILGETFRCKWEH---PDGSTTFYMAEQVSHHPPVSSL 343
Query: 143 TIFNDKNQVSLEGYNQVKASISKMSLNVKQYGHAILNFGKLNEQYLITLPPLHIEGLLAA 202
I N K ++ G K+ SL+ G L L E Y++ LP + +G++
Sbjct: 344 FITNRKAGFNISGTILAKSKYYGNSLSAILAGKLRLTLLNLGETYIVNLPYANCKGIMIG 403
Query: 203 SPFVELEGKSYIQA-SNGLYCSIEFSGKGYFSGKKNSFKARI 243
+ +EL G+ I+ G +++F K G N + I
Sbjct: 404 TMTMELGGEVNIECEKTGYRTTLDFKLKPMLGGAYNQIEGSI 445
>Hs22066714 [T] KOG2210 Oxysterol-binding protein
Length = 578
Score = 81.6 bits (200), Expect = 2e-15
Identities = 65/209 (31%), Positives = 97/209 (46%), Gaps = 21/209 (10%)
Query: 1 MSQYASSSSWTSFLKSISSFNGDLSSLTAPPFILSPVS-LTEYSEYWAEHPDLFLEPSFI 59
+S+ S WT LK + DLS + P F+L P S L + S+Y+ H DL +
Sbjct: 363 VSEENKSLMWT-LLKQLRP-GMDLSRVVLPTFVLEPRSFLNKLSDYYY-HADLLSRAAVE 419
Query: 60 TEPDSDGTPPELLRMLAVVKWFISTLKSQYCSRNESMGSEKKPLNPFLGEVFVGKWNNKS 119
+ S RM V++W++S + KKP NP LGE F W +
Sbjct: 420 EDAYS--------RMKLVLRWYLSGFYKK-------PKGIKKPYNPILGETFRCCWFHPQ 464
Query: 120 NPEFGETVLLSEQVSHHPPITAYTIFNDKNQVSLEGYNQVKASISKMSLNVKQYGHAILN 179
T ++EQVSHHPP++A+ + N K+ + G K+ SL+ G A L
Sbjct: 465 TDS--RTFYIAEQVSHHPPVSAFHVSNRKDGFCISGSITAKSRFYGNSLSALLDGKATLT 522
Query: 180 FGKLNEQYLITLPPLHIEGLLAASPFVEL 208
F E Y +T+P H +G+L + +EL
Sbjct: 523 FLNRAEDYTLTMPYAHCKGILYGTMTLEL 551
>7291708 [T] KOG2209 Oxysterol-binding protein
Length = 455
Score = 68.9 bits (167), Expect = 1e-11
Identities = 70/248 (28%), Positives = 103/248 (41%), Gaps = 42/248 (16%)
Query: 23 DLSSLTAPPFILSPVS----LTEYSEYWAEHPDLFLEPSFITEPDSDGTPPELLRMLAVV 78
DLS +T P + P+S L EY EY +TE P + RM V
Sbjct: 38 DLSKITMPVMLNEPLSFLQRLCEYMEY----------AQLLTEAAQQEHPAD--RMKYVA 85
Query: 79 KWFISTLKSQYCSRNESMGSEKKPLNPFLGEVFVGKWNNKSNPEFGETVLLSEQVSHHPP 138
+ +S L S + E +G KP NP LGE + + G+ ++ EQVSHHPP
Sbjct: 86 AFAVSALASNW----ERLG---KPFNPLLGETY--------ELQKGDYRIVCEQVSHHPP 130
Query: 139 ITAYTIFNDKNQVSLEGYNQVKASISKMSLNVKQYGHAILNFGKLNEQYLITLPPLHIEG 198
++A+ + G K S+ V G + F K NE Y T +
Sbjct: 131 VSAF--HAESKDFKFHGTISPKIKFWGKSVEVNPKGTVTVEFPKWNESYSWTNVNCCVHN 188
Query: 199 LLAASPFVELEGKSYI-QASNGLYCSIEFSGKGYFSGKKNSFKARIF-KSFNDSNDKHNA 256
++ ++E GK I + G S+ F G SG KN + F K +++N
Sbjct: 189 IIVGRLWIEQYGKMEITNHATGHVASLTFKSAG--SGAKNLHRVEGFVKDASETN----- 241
Query: 257 LYTIAGQW 264
LY + G+W
Sbjct: 242 LYFLYGKW 249
>Hs19718746 [T] KOG2209 Oxysterol-binding protein
Length = 437
Score = 66.6 bits (161), Expect = 6e-11
Identities = 70/258 (27%), Positives = 104/258 (40%), Gaps = 31/258 (12%)
Query: 8 SSWTSFLKSISSFNGDLSSLTAPPFILSPVSLTEYSEYWAEHPDLFLEPSFITEPDSDGT 67
S W+ K I +LS +T P P+S + + EH L + S +++P
Sbjct: 35 SIWSILRKCIGM---ELSKITMPVIFNEPLSFLQRLTEYMEHTYLIHKASSLSDP----- 86
Query: 68 PPELLRMLAVVKWFISTLKSQYCSRNESMGSEKKPLNPFLGEVFVGKWNNKSNPEFGETV 127
+ RM V + +S + SQ+ E G KP NP LGE + + G
Sbjct: 87 ---VERMQCVAAFAVSAVASQW----ERTG---KPFNPLLGETY-----ELVRDDLGFR- 130
Query: 128 LLSEQVSHHPPITAYTIFNDKNQVSLEGYNQVKASISKMSLNVKQYGHAILNFGKLNEQY 187
L+SEQVSHHPPI+A+ N G K S+ + G L + NE Y
Sbjct: 131 LISEQVSHHPPISAFHAEGLNNDFIFHGSIYPKLKFWGKSVEAEPKGTITLELLEHNEAY 190
Query: 188 LITLPPLHIEGLLAASPFVELEGK-SYIQASNGLYCSIEFSGKGYFSGKKNSFKARIFKS 246
T P + ++ ++E G I G C + F G F + + + I
Sbjct: 191 TWTNPTCCVHNIIVGKLWIEQYGNVEIINHKTGDKCVLNFKPCGLFGKELHKVEGYI--- 247
Query: 247 FNDSNDKHNALYTIAGQW 264
+ S K ALY G+W
Sbjct: 248 QDKSKKKLCALY---GKW 262
>Hs19718741 [T] KOG2209 Oxysterol-binding protein
Length = 950
Score = 66.6 bits (161), Expect = 6e-11
Identities = 70/258 (27%), Positives = 104/258 (40%), Gaps = 31/258 (12%)
Query: 8 SSWTSFLKSISSFNGDLSSLTAPPFILSPVSLTEYSEYWAEHPDLFLEPSFITEPDSDGT 67
S W+ K I +LS +T P P+S + + EH L + S +++P
Sbjct: 548 SIWSILRKCIGM---ELSKITMPVIFNEPLSFLQRLTEYMEHTYLIHKASSLSDP----- 599
Query: 68 PPELLRMLAVVKWFISTLKSQYCSRNESMGSEKKPLNPFLGEVFVGKWNNKSNPEFGETV 127
+ RM V + +S + SQ+ E G KP NP LGE + + G
Sbjct: 600 ---VERMQCVAAFAVSAVASQW----ERTG---KPFNPLLGETY-----ELVRDDLGFR- 643
Query: 128 LLSEQVSHHPPITAYTIFNDKNQVSLEGYNQVKASISKMSLNVKQYGHAILNFGKLNEQY 187
L+SEQVSHHPPI+A+ N G K S+ + G L + NE Y
Sbjct: 644 LISEQVSHHPPISAFHAEGLNNDFIFHGSIYPKLKFWGKSVEAEPKGTITLELLEHNEAY 703
Query: 188 LITLPPLHIEGLLAASPFVELEGK-SYIQASNGLYCSIEFSGKGYFSGKKNSFKARIFKS 246
T P + ++ ++E G I G C + F G F + + + I
Sbjct: 704 TWTNPTCCVHNIIVGKLWIEQYGNVEIINHKTGDKCVLNFKPCGLFGKELHKVEGYI--- 760
Query: 247 FNDSNDKHNALYTIAGQW 264
+ S K ALY G+W
Sbjct: 761 QDKSKKKLCALY---GKW 775
>At5g57240 [T] KOG2210 Oxysterol-binding protein
Length = 379
Score = 65.9 bits (159), Expect = 1e-10
Identities = 82/352 (23%), Positives = 135/352 (38%), Gaps = 46/352 (13%)
Query: 23 DLSSLTAPPFI-LSPVSLTEYSE--YWAEHPDLFLEPSFITEPDSDGTPPELLRMLAVVK 79
DL++ PP + L+ L Y E Y + DL E S +P + RM A+V
Sbjct: 42 DLTNFQLPPQMNLARSQLQCYGEIVYSFDGHDLLGECSRRDKP--------IERMKAMVT 93
Query: 80 WFISTLKSQYCSRNESMGSEKKPLNPFLGEVFVGKWNNKSNPEFGETVLLSEQVSHHPPI 139
W+ISTL+ P NP +GE ++ SN G +L+EQ+SHHPP+
Sbjct: 94 WYISTLRPLIFGL--------APYNPVIGET-----HHVSN---GHINVLAEQISHHPPV 137
Query: 140 TAYTIFNDKNQVSLEGYNQVKASISKMSLNVKQYGHAILNFGKLNEQYLITLPPLHIEGL 199
+A ++K V + ++V+ G ++ E Y + P L + L
Sbjct: 138 SALHATHEKENVDVLLCQYFTPKFRGAYVDVEVKGKRVVKLLNHKETYEMNQPKLLMTFL 197
Query: 200 LAASPFVELEGKSYIQA-SNGLYCSIEFSGKGYFS----GKKNSFKARIFKSFNDSNDKH 254
A GK I+ GL ++ + S K + K +IF+S
Sbjct: 198 PAMG--AHWAGKIVIKCPETGLGAELQLLSDSFLSRFTGNNKRAIKGKIFES-----SSR 250
Query: 255 NALYTIAGQWXXXXXXXXXXXXXXETVFYDASKLS-VETLTVKSIEEQHPLESRKAWQLV 313
LY I+G W E ++ + ++ ++T V++++E ES W V
Sbjct: 251 KQLYEISGHWDRTVTAKNTKTGQLEVIYKASENIAKLKTPIVENLQEVSESESAVVWGEV 310
Query: 314 AAATKSGNFDLIHXXXXXXXXXXXXXXXXXXAKGIDWQRRWF------KDYD 359
+ + N++ A G W + F KD+D
Sbjct: 311 SEGIVTNNWEKAREAKRDVEEKQRESLRKRKASGQSWIPKHFSVARTGKDWD 362
>Hs7662298 [T] KOG2209 Oxysterol-binding protein
Length = 468
Score = 64.3 bits (155), Expect = 3e-10
Identities = 69/258 (26%), Positives = 101/258 (38%), Gaps = 31/258 (12%)
Query: 8 SSWTSFLKSISSFNGDLSSLTAPPFILSPVSLTEYSEYWAEHPDLFLEPSFITEPDSDGT 67
S WT K + +LS +T P P+S + + EH L S +P
Sbjct: 63 SVWTILKKCVGL---ELSKITMPIAFNEPLSFLQRITEYMEHVYLIHRASCQPQP----- 114
Query: 68 PPELLRMLAVVKWFISTLKSQYCSRNESMGSEKKPLNPFLGEVFVGKWNNKSNPEFGETV 127
L RM +V + +S + SQ+ E G KP NP LGE + + G
Sbjct: 115 ---LERMQSVAAFAVSAVASQW----ERTG---KPFNPLLGETY-----ELIREDLGFR- 158
Query: 128 LLSEQVSHHPPITAYTIFNDKNQVSLEGYNQVKASISKMSLNVKQYGHAILNFGKLNEQY 187
+SEQVSHHPPI+A+ + G K S+ + G L K NE Y
Sbjct: 159 FISEQVSHHPPISAFHSEGLNHDFLFHGSIYPKLKFWGKSVEAEPRGTITLELLKHNEAY 218
Query: 188 LITLPPLHIEGLLAASPFVELEGK-SYIQASNGLYCSIEFSGKGYFSGKKNSFKARIFKS 246
T P + ++ ++E G + G C + F G F + + + I
Sbjct: 219 TWTNPTCCVHNVIIGKLWIEQYGTVEILNHRTGHKCVLHFKPCGLFGKELHKVEGHI--- 275
Query: 247 FNDSNDKHNALYTIAGQW 264
D N K L+ I G+W
Sbjct: 276 -QDKNKK--KLFMIYGKW 290
>Hs21450853 [T] KOG2209 Oxysterol-binding protein
Length = 480
Score = 64.3 bits (155), Expect = 3e-10
Identities = 69/258 (26%), Positives = 101/258 (38%), Gaps = 31/258 (12%)
Query: 8 SSWTSFLKSISSFNGDLSSLTAPPFILSPVSLTEYSEYWAEHPDLFLEPSFITEPDSDGT 67
S WT K + +LS +T P P+S + + EH L S +P
Sbjct: 75 SVWTILKKCVGL---ELSKITMPIAFNEPLSFLQRITEYMEHVYLIHRASCQPQP----- 126
Query: 68 PPELLRMLAVVKWFISTLKSQYCSRNESMGSEKKPLNPFLGEVFVGKWNNKSNPEFGETV 127
L RM +V + +S + SQ+ E G KP NP LGE + + G
Sbjct: 127 ---LERMQSVAAFAVSAVASQW----ERTG---KPFNPLLGETY-----ELIREDLGFR- 170
Query: 128 LLSEQVSHHPPITAYTIFNDKNQVSLEGYNQVKASISKMSLNVKQYGHAILNFGKLNEQY 187
+SEQVSHHPPI+A+ + G K S+ + G L K NE Y
Sbjct: 171 FISEQVSHHPPISAFHSEGLNHDFLFHGSIYPKLKFWGKSVEAEPRGTITLELLKHNEAY 230
Query: 188 LITLPPLHIEGLLAASPFVELEGK-SYIQASNGLYCSIEFSGKGYFSGKKNSFKARIFKS 246
T P + ++ ++E G + G C + F G F + + + I
Sbjct: 231 TWTNPTCCVHNVIIGKLWIEQYGTVEILNHRTGHKCVLHFKPCGLFGKELHKVEGHI--- 287
Query: 247 FNDSNDKHNALYTIAGQW 264
D N K L+ I G+W
Sbjct: 288 -QDKNKK--KLFMIYGKW 302
>At4g25860 [T] KOG2210 Oxysterol-binding protein
Length = 380
Score = 60.1 bits (144), Expect = 6e-09
Identities = 79/310 (25%), Positives = 125/310 (39%), Gaps = 37/310 (11%)
Query: 12 SFLKSISSFNGDLSSLTAPPFILSPVSLTEYSEYWAEHPDLFLEPSFITEPDSDGTPPEL 71
S +K++ DL++ PP ++ P S + + E F + E P E
Sbjct: 32 SLIKTVRP-GSDLTNFQLPPQLILPRSRLQC---YGEMIYSFGGQDLLGECSRRNIPIE- 86
Query: 72 LRMLAVVKWFISTLKSQYCSRNESMGSEKKPLNPFLGEVFVGKWNNKSNPEFGETVLLSE 131
R+ +VV W ISTL+ + P NP LGE ++ SN G +L+E
Sbjct: 87 -RLKSVVTWNISTLRPVVVGMS--------PYNPILGET-----HHVSN---GYINVLTE 129
Query: 132 QVSHHPPITAYTIFNDKNQVSLEGYNQVKASISKMSLNVKQYGHAILNFGKLNEQYLITL 191
QV HHPP++A +++ + + ++V+ G I+ E Y +
Sbjct: 130 QVMHHPPVSALHATHEQENIDVTWCQYFTPKFRGAYVDVEVNGKRIMKLLHHKETYEMDQ 189
Query: 192 PPLHIEGLLAASPFVELEGKSYIQA-SNGLYCSIEFSGKGY---FSGKKN-SFKARIFKS 246
P L ++ L A P GK I+ L + + F G N S K +IF+S
Sbjct: 190 PRLIMKFLPA--PGAHWAGKVKIKCPETDLEAELHLISDSFIERFRGNNNRSIKGKIFES 247
Query: 247 FNDSNDKHNALYTIAGQWXXXXXXXXXXXXXXETVFYDASK--LSVETLTVKSIEEQHPL 304
N LY I G W E V Y+A++ ++ TVK+++E
Sbjct: 248 -----SSGNQLYNIFGHWDRTVMAKNLKTGGLE-VIYNANENITGLKPPTVKNLQEVMES 301
Query: 305 ESRKAWQLVA 314
ES W V+
Sbjct: 302 ESTIVWSEVS 311
>YHR073w [I] KOG1737 Oxysterol-binding protein
Length = 996
Score = 59.7 bits (143), Expect = 8e-09
Identities = 66/260 (25%), Positives = 105/260 (40%), Gaps = 29/260 (11%)
Query: 5 ASSSSWTSFLKSISSFNGDLSSLTAPPFILSPVSLTEYSEYWAEHPDLFLEPSFITEPDS 64
AS S SFL+ + DLSS+ P P+S+ + E+ L + + +P
Sbjct: 638 ASPPSLLSFLRK--NVGKDLSSIAMPVTSNEPISILQLISETFEYAPLLTKATQRPDP-- 693
Query: 65 DGTPPELLRMLAVVKWFISTLKSQYCSRNESMGSEKKPLNPFLGEVFVGKWNNKSNPEFG 124
+ V F + S Y + ++ +KP NP L E F + G
Sbjct: 694 ----------ITFVSAFAISFLSIYRDKTRTL---RKPFNPLLAETF-----ELIREDMG 735
Query: 125 ETVLLSEQVSHHPPITAYTIFNDKNQVSLEGYNQVKASISKMSLNVKQYGHAILNFGKLN 184
L+SE+VSH PP+ A+ + + S K + LN + G L F
Sbjct: 736 FR-LISEKVSHRPPVFAFFAEHLDWECSYTVTPSQKFWGKSIELNNE--GILRLKFKTTG 792
Query: 185 EQYLITLPPLHIEGLLAASPFVELEGKSYIQASNGLYCSIEFSGKGYFSGKKNSFKARIF 244
E + T P ++ L+A ++E + + +S G I F G FSG+ FK I
Sbjct: 793 ELFEWTQPTTILKNLIAGERYMEPVNEFEVHSSKGDKSHILFDKAGMFSGRSEGFKVSII 852
Query: 245 KSFNDSNDKHNALYTIAGQW 264
+ + K T+AG+W
Sbjct: 853 PPPSSNRKKE----TLAGKW 868
>YDL019c [I] KOG1737 Oxysterol-binding protein
Length = 1283
Score = 59.3 bits (142), Expect = 1e-08
Identities = 65/247 (26%), Positives = 103/247 (41%), Gaps = 34/247 (13%)
Query: 23 DLSSLTAPPFILSPVSLTEYSEYWAEHPDLFLEPSFITEPDSDGTPPELLRMLAVVKWFI 82
D++ +T P P SL + E+ +L + + T DS LR L V +
Sbjct: 909 DMTRMTLPVTFNEPTSLLQRVAEDLEYSELLDQAA--TFEDST------LRTLYVAAFTA 960
Query: 83 STLKSQYCSRNESMGSEKKPLNPFLGEVFVGKWNNKSNPEFGETVLLSEQVSHHPPITAY 142
S+ Y S + + KP NP LGE F +K F +EQVSHHPPI+A
Sbjct: 961 SS----YASTTKRVA---KPFNPLLGETFEYSRPDKQYRFF------TEQVSHHPPISA- 1006
Query: 143 TIFNDKNQVSLEGYNQVKASISKMSLNVKQYG--HAIL--NFGKLNEQYLITLPPLHIEG 198
+ + + G + V + S NVK G H L N + E Y P + G
Sbjct: 1007 -TWTESPRWDFWGESFVDTKFNGRSFNVKHLGLWHIKLRPNDNEKEELYTWKKPNNTVIG 1065
Query: 199 LLAASPFVELEGK-SYIQASNGLYCSIEFSGKGYFSGKKNSFKARIFKSFNDSNDKHNAL 257
+L +P V+ G+ + + + G +C + F +G+ S ++ N K +
Sbjct: 1066 ILIGNPQVDNHGEVNVVNHTTGDHCKLYFKARGWRSSGAYEITGEVY------NKKKQKV 1119
Query: 258 YTIAGQW 264
+ + G W
Sbjct: 1120 WILGGHW 1126
>At4g25850 [T] KOG2210 Oxysterol-binding protein
Length = 378
Score = 58.5 bits (140), Expect = 2e-08
Identities = 81/355 (22%), Positives = 130/355 (35%), Gaps = 40/355 (11%)
Query: 23 DLSSLTAPPFILSPVSLTEYSEYWAEHPDLFLEPSFITEPDSDGTPPELLRMLAVVKWFI 82
DL++ PP + P S + + E F+ + E P E R+ +VV W I
Sbjct: 42 DLTNFQLPPQLNLPRSQLQC---YGEMVYSFVGQDLLGECSRRDLPIE--RLKSVVTWNI 96
Query: 83 STLKSQYCSRNESMGSEKKPLNPFLGEVFVGKWNNKSNPEFGETVLLSEQVSHHPPITAY 142
STL+ + P N LGE ++ SN G +++EQV HHPP++A
Sbjct: 97 STLRPVVFGMS--------PYNSVLGET-----HHVSN---GHINVIAEQVVHHPPVSAL 140
Query: 143 TIFNDKNQVSLEGYNQVKASISKMSLNVKQYGHAILNFGKLNEQYLITLPPLHIEGLLAA 202
+++ + + ++V+ G ++ E Y + P L + L A
Sbjct: 141 HATHEQENIDVTWCQYFTPKFRGTHVDVEVKGKRVMKLLNHIETYEMDQPRLIMRFLPA- 199
Query: 203 SPFVELEGKSYIQA-SNGLYCSIEFSGKGY---FSGKKN-SFKARIFKSFNDSNDKHNAL 257
P GK I+ L + + F G N S K +IF+S N L
Sbjct: 200 -PGAYWAGKVKIKCPETDLEAELHLISDSFIERFRGNNNRSIKGKIFES-----SSGNQL 253
Query: 258 YTIAGQWXXXXXXXXXXXXXXETVFYDASKLS-VETLTVKSIEEQHPLESRKAWQLVAAA 316
Y I G W E ++ ++ ++ TVK++EE ES W V+
Sbjct: 254 YNIFGHWDRTVMAKNIKTGELEVIYNAKENITGLKPPTVKNLEEVTESESTMVWSEVSEG 313
Query: 317 TKSGNFDLIHXXXXXXXXXXXXXXXXXXAKGIDWQRRWF------KDYDYSEKDP 365
+++ A G W + F KD+D S P
Sbjct: 314 ILKKDWERAREAKIVVEEKQRASLKQREASGESWVPKHFLVVKDGKDWDCSPLQP 368
>Hs17473098 [T] KOG2210 Oxysterol-binding protein
Length = 256
Score = 57.4 bits (137), Expect = 4e-08
Identities = 63/255 (24%), Positives = 106/255 (40%), Gaps = 29/255 (11%)
Query: 74 MLAVVKWFISTLKSQYCSRNESMGSEKKPLNPFLGEVFVGKWNNKSNPEFGETVLLSE-- 131
M+ VVK ++S ++ R S+ KKP +P LG++F W ++ E T L+SE
Sbjct: 1 MVLVVKSYLSAFHAR---RKGSVA--KKPYSPILGKIFQCHWTLPNDTE-ENTKLVSERP 54
Query: 132 --------------QVSHHPPITAYTIFNDKNQVSLEGYNQVKASISKMSLNVKQYGHAI 177
Q+SHHPPI+A+ + ++ + K+ MS+ V G
Sbjct: 55 VPWVSKNTVTFVADQISHHPPISAFYVEYFNKKIQFTAHVWAKSKFLGMSIGVHNIGQGC 114
Query: 178 LNFGKLNEQYLITLPPLHIEGLLAASPFVELEGKSYIQASNGLYCSIEFSGKGYFSGKKN 237
++ +E Y++T + +L S +V+L G+ I S I S +
Sbjct: 115 VSCLDYDEHYILTFLNGYGRSILTWS-WVKLGGECCINCSKQARVQISSS---ILNPSMW 170
Query: 238 SFKARIFKSFNDSNDKHNALYTIAGQWXXXXXXXXXXXXXXETVFYDASKLSVETLTVKS 297
+ ++ F +DK + T G+W T F D KL V V
Sbjct: 171 ARSTKLLLRFFSPSDKKSFCST-EGEW--NGLMYAKYATWENTSFADTKKLPVIKKKVMK 227
Query: 298 IEEQHPLESRKAWQL 312
+E+Q+ L S ++ L
Sbjct: 228 LEDQNKLCSSQSLHL 242
>CE23653 [T] KOG2209 Oxysterol-binding protein
Length = 471
Score = 57.0 bits (136), Expect = 5e-08
Identities = 46/166 (27%), Positives = 69/166 (40%), Gaps = 19/166 (11%)
Query: 101 KPLNPFLGEVFVGKWNNKSNPEFGETVLLSEQVSHHPPITAYTIFNDKNQVSLEGYNQVK 160
KP NP L E F + N L+EQVSHHPPI+A ++ + ++ ++EG +
Sbjct: 154 KPFNPLLLETFELERNGVR--------FLAEQVSHHPPISA--VYAESDEFTVEGTVEPT 203
Query: 161 ASISKMSLNVKQYGHAILNFGKLNEQYLITLPPLHIEGLLAASPFVELEGKSYIQASNGL 220
L + H L F K E Y + P I ++ ++ I++S
Sbjct: 204 LGFWMTKLLANPHAHLKLTFKKTGETYSWSAPKCAIYNVIMGKMYMNFTSHMKIESSGTY 263
Query: 221 YCSIEFSGKGYFSGKKNS--FKARIFKSFNDSNDKHNALYTIAGQW 264
F KGY++ K + IF+ N K ALY G W
Sbjct: 264 DAVFSFDNKGYYNHKGGDVHVEGHIFEGKN----KIKALY---GNW 302
>YAR044w [I] KOG1737 Oxysterol-binding protein
Length = 859
Score = 55.5 bits (132), Expect = 1e-07
Identities = 67/260 (25%), Positives = 100/260 (37%), Gaps = 38/260 (14%)
Query: 12 SFLKSISSFNGDLSSLTAPPFILSPVSLTEYSEYWAEHPDLFLEPSFITEPDSDGTPPEL 71
S LKS+ DL+ LT P P SL + E+ + + + T DS
Sbjct: 473 SVLKSM--VGQDLTKLTLPVSFNEPTSLLQRVSEDIEYSHILDQAA--TFEDSS------ 522
Query: 72 LRMLAVVKWFISTLKSQYCSRNESMGSEKKPLNPFLGEVFVGKWNNKSNPEFGETVLLSE 131
LRML V + S Y S + KP NP LGE F + G+ +E
Sbjct: 523 LRMLYVAAF----TASMYASTTNRVS---KPFNPLLGETFEYARTD------GQYRFFTE 569
Query: 132 QVSHHPPITAYTIFNDKNQVSLEGYNQVKASISKMSLNVKQYGHAIL------NFGKLNE 185
QVSHHPPI+A + + + G V +S + + V+ G + N E
Sbjct: 570 QVSHHPPISA--TWTESPKWDFYGECNVDSSFNGRTFAVQHLGLWYITIRPDHNISVPEE 627
Query: 186 QYLITLPPLHIEGLLAASPFVELEGKSYI-QASNGLYCSIEFSGKGYFSGKKNSFKARIF 244
Y P + G+L P V+ G + + G YC + + G+ S + +F
Sbjct: 628 TYSWKKPNNTVIGILMGKPQVDNSGDVKVTNHTTGDYCMLHYKAHGWTSAGAYEVRGEVF 687
Query: 245 KSFNDSNDKHNALYTIAGQW 264
N L+ + G W
Sbjct: 688 ------NKDDKKLWVLGGHW 701
>SPBC646.08c [T] KOG2210 Oxysterol-binding protein
Length = 516
Score = 54.3 bits (129), Expect = 3e-07
Identities = 46/197 (23%), Positives = 77/197 (38%), Gaps = 14/197 (7%)
Query: 127 VLLSEQVSHHPPITAYTIFNDKNQVSLEGYNQVKASISKMSLNV---KQYGHAILNFGKL 183
V ++EQ SHHP ++A+ + + + G +Q+ + S V + F K
Sbjct: 245 VFMAEQTSHHPAVSAFYVTCPSKGIEVYGQDQIAVGFTGTSFKVCAGDLNKGVYVRFNKR 304
Query: 184 -NEQYLITLPPLHIEGLLAASPFVELEGKSYIQASNGLYCSIEFSGKGYFSGKKNSFKAR 242
NE+YL T P + G+L + + L + I +I + + GK S
Sbjct: 305 DNEEYLCTHPSASVGGILRGNLHINLLDSTVILCPKTRIKTIITYIEERWLGKPRSLVEG 364
Query: 243 IFKSFNDSND---------KHNALYTIAGQWXXXXXXXXXXXXXXETVFYDASKLSVETL 293
+ ++ SND K N L T G W + D ++L +
Sbjct: 365 VCYRYDPSNDTIDSIKAVPKENILATFKGNWRNCIFYSYAGESESR-MLVDLNELDLVHK 423
Query: 294 TVKSIEEQHPLESRKAW 310
+++Q P ESRK W
Sbjct: 424 RCPPLDKQFPFESRKIW 440
>SPBC2F12.05c_2 [I] KOG1737 Oxysterol-binding protein
Length = 499
Score = 52.4 bits (124), Expect = 1e-06
Identities = 55/226 (24%), Positives = 97/226 (42%), Gaps = 29/226 (12%)
Query: 23 DLSSLTAPPFILSPVSLTEYSEYWAEHPDLFLEPSFITEPDSDGTPPELLRMLAVVKWFI 82
D++ +T P P SL + E+ +L + S +P R+L V +
Sbjct: 138 DMTKMTLPVSFNEPTSLLQRVAEDMEYTELLDQASHNKDPYQ--------RILYVAAF-- 187
Query: 83 STLKSQYCSRNESMGSEKKPLNPFLGEVFVGKWNNKSNPEFGETVLLSEQVSHHPPITAY 142
S+Y S ++ KP NP LGE + +P+ G ++ EQVSHHPP+ A
Sbjct: 188 --AASEYAS---TLNRVAKPFNPLLGETY-----EFCHPQRGFRFIV-EQVSHHPPVGA- 235
Query: 143 TIFNDKNQVSLEGYNQVKASISKMSLNVKQYGHAILNF----GKLNEQYLITLPPLHIEG 198
+++ G + VK+ S ++ G L G++ E Y + G
Sbjct: 236 -AYSESANWKYYGESSVKSKFYGKSFDISPLGTWFLELRHPSGEV-ELYTWKKVTSSVVG 293
Query: 199 LLAASPFVELEGKSYI-QASNGLYCSIEFSGKGYFSGKKNSFKARI 243
++ SP V+ G+ +I S+G+ C ++F +G+ + K +
Sbjct: 294 IILGSPSVDNYGQMHIVNHSSGINCVLDFKPRGWRGTNAHEVKGSV 339
>Hs22035612 [I] KOG1737 Oxysterol-binding protein
Length = 938
Score = 50.1 bits (118), Expect = 6e-06
Identities = 60/244 (24%), Positives = 101/244 (40%), Gaps = 30/244 (12%)
Query: 23 DLSSLTAPPFILSPVSLTEYSEYWAEHPDLFLEPSFITEPDSDGTPPELLRMLAVVKWFI 82
DLS ++ P + P++ ++ E+ +L + S +P RM+ V + +
Sbjct: 586 DLSKVSMPVELNEPLNTLQHLCEEMEYSELLDKASETDDPYE--------RMVLVAAFAV 637
Query: 83 STLKSQYCSRNESMGSEKKPLNPFLGEVFVGKWNNKSNPEFGETVLLSEQVSHHPPITAY 142
S YCS GS KP NP LGE + +K F SEQVSHHPPI+A
Sbjct: 638 SG----YCSTYFRAGS--KPFNPVLGETYECIREDKGFRFF------SEQVSHHPPISAC 685
Query: 143 TIFNDKNQVSLEGYNQVKASISKMSLNVKQYGHAILNFGKLNEQYLITLPPLHIEGLLAA 202
KN V + + K S+ + G + K + Y+ I +L+
Sbjct: 686 HC-ESKNFVFWQDI-RWKNKFWGKSMEILPVGTLNVMLPKYGDYYVWNKVTTCIHNILSG 743
Query: 203 SPFVELEGKSYIQ--ASNGLYCSIEFSGKGYFSGKKNSFKARIFKSFNDSNDKHNALYTI 260
++E G+ I+ S+ C + F Y++ N + + + + A+Y +
Sbjct: 744 RRWIEHYGEVTIRNTKSSVCICKLTFVKVNYWNSNMNEVQGVVI------DQEGKAVYRL 797
Query: 261 AGQW 264
G+W
Sbjct: 798 FGKW 801
>Hs14210532 [I] KOG1737 Oxysterol-binding protein
Length = 934
Score = 50.1 bits (118), Expect = 6e-06
Identities = 60/244 (24%), Positives = 101/244 (40%), Gaps = 30/244 (12%)
Query: 23 DLSSLTAPPFILSPVSLTEYSEYWAEHPDLFLEPSFITEPDSDGTPPELLRMLAVVKWFI 82
DLS ++ P + P++ ++ E+ +L + S +P RM+ V + +
Sbjct: 582 DLSKVSMPVELNEPLNTLQHLCEEMEYSELLDKASETDDPYE--------RMVLVAAFAV 633
Query: 83 STLKSQYCSRNESMGSEKKPLNPFLGEVFVGKWNNKSNPEFGETVLLSEQVSHHPPITAY 142
S YCS GS KP NP LGE + +K F SEQVSHHPPI+A
Sbjct: 634 SG----YCSTYFRAGS--KPFNPVLGETYECIREDKGFRFF------SEQVSHHPPISAC 681
Query: 143 TIFNDKNQVSLEGYNQVKASISKMSLNVKQYGHAILNFGKLNEQYLITLPPLHIEGLLAA 202
KN V + + K S+ + G + K + Y+ I +L+
Sbjct: 682 HC-ESKNFVFWQDI-RWKNKFWGKSMEILPVGTLNVMLPKYGDYYVWNKVTTCIHNILSG 739
Query: 203 SPFVELEGKSYIQ--ASNGLYCSIEFSGKGYFSGKKNSFKARIFKSFNDSNDKHNALYTI 260
++E G+ I+ S+ C + F Y++ N + + + + A+Y +
Sbjct: 740 RRWIEHYGEVTIRNTKSSVCICKLTFVKVNYWNSNMNEVQGVVI------DQEGKAVYRL 793
Query: 261 AGQW 264
G+W
Sbjct: 794 FGKW 797
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.314 0.131 0.389
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,546,350
Number of Sequences: 60738
Number of extensions: 1004067
Number of successful extensions: 1899
Number of sequences better than 1.0e-05: 34
Number of HSP's better than 0.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 25
Number of HSP's that attempted gapping in prelim test: 1807
Number of HSP's gapped (non-prelim): 39
length of query: 415
length of database: 30,389,216
effective HSP length: 109
effective length of query: 306
effective length of database: 23,768,774
effective search space: 7273244844
effective search space used: 7273244844
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)