ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIV1901 good E KOG3923 Amino acid transport and metabolism D-aspartate oxidase
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIV1901 650626 651735 370
(370 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
SPCC1450.07c [E] KOG3923 D-aspartate oxidase 127 3e-29
Hs4503289 [E] KOG3923 D-aspartate oxidase 97 4e-20
Hs5231298 [E] KOG3923 D-aspartate oxidase 75 2e-13
Hs21536470 [E] KOG3923 D-aspartate oxidase 63 6e-10
HsM4503255 [E] KOG3923 D-aspartate oxidase 62 1e-09
CE15718 [E] KOG3923 D-aspartate oxidase 60 4e-09
CE07083 [E] KOG3923 D-aspartate oxidase 60 5e-09
CE26739 [E] KOG3923 D-aspartate oxidase 57 3e-08
>SPCC1450.07c [E] KOG3923 D-aspartate oxidase
Length = 348
Score = 127 bits (318), Expect = 3e-29
Identities = 108/360 (30%), Positives = 173/360 (48%), Gaps = 43/360 (11%)
Query: 3 VCIVGAGVIGLSSALRLLETRPDIRTITIVSEQFPQDQPINHTFTSPWAGAHFRPFPHRD 62
+ IVGAGVIGL++A L + R I ++++ P+D+ + +TSPWAGA+F
Sbjct: 10 IVIVGAGVIGLTTAWILSDLGLAPR-IKVIAKYTPEDRSVE--YTSPWAGANFC------ 60
Query: 63 SDYASDKRESEYTRVTYNYFKRKSKQWLSEATVEFMNGID-WLENPSIEYQRLGAGYNGS 121
S A+D + ++TY+ F +K EA + F + + W P + R Y
Sbjct: 61 SISATDDNALRWDKITYHRFAYLAKT-RPEAGIRFADLRELWEYEPKHDKIRSWNTY--- 116
Query: 122 SLEKFQQ-QDSNLPAGVTFGCSYETWCLNAPLYLLFLYDQVMKKSEQQNVNIRVKRIKLE 180
+ F+ + +LP +G T+ +NAP YL ++Y +++ + ++ +L
Sbjct: 117 -VRDFKVIPEKDLPGECIYGHKATTFLINAPHYLNYMYKLLIE------AGVEFEKKELS 169
Query: 181 KLKDICELYPDVNIVVNASGCGLQWEGGL-DPKCFLVRGQTLLLDVGDKHDTIPYAHATI 239
+K+ E P+ ++V N +G GG+ DP + RG +L+ P+ T
Sbjct: 170 HIKETVEETPEASVVFNCTGLWASKLGGVEDPDVYPTRGHVVLVKA-------PHVTETR 222
Query: 240 THQAKSGDWTFVIKRPGKNGKKAYYILGGTKQPGDYSVMPRDTDTEKLIGRGKKLFPELL 299
K+ D T++I RP G I GG QPG++ DT ++ R L PEL
Sbjct: 223 ILNGKNSD-TYIIPRPLNGG----VICGGFMQPGNWDREIHPEDTLDILKRTSALMPELF 277
Query: 300 -----ENFEIKNVNVGFRPLRVGGSRVELEFNKSPDGEQMPVIHAYGLGGMGFETSMGVA 354
E EI VGFRP R GG+RVEL+ G +P++H YG G G++ G+A
Sbjct: 278 HGKGPEGAEIIQECVGFRPSRKGGARVELDV---VPGTSVPLVHDYGASGTGYQAGYGMA 334
>Hs4503289 [E] KOG3923 D-aspartate oxidase
Length = 341
Score = 97.1 bits (240), Expect = 4e-20
Identities = 101/359 (28%), Positives = 165/359 (45%), Gaps = 41/359 (11%)
Query: 3 VCIVGAGVIGLSSALRLLETRPDIRTITIVSEQFPQDQPINHTFTSPWAGAHFRPFPHRD 62
+ +VGAGV+GLS+A+ + + P ++TI+S++F D TS A P + D
Sbjct: 6 IAVVGAGVVGLSTAVCISKLVPRC-SVTIISDKFTPDT------TSDVAAGMLIPHTYPD 58
Query: 63 SDYASDKRESEYTRVTYNY-FKRKSKQWLSEATVEFMNGIDWLENPSIEYQRLGAGYNGS 121
+ + K ++ R T+N+ F + +A V ++G ++ E A
Sbjct: 59 TPIHTQK---QWFRETFNHLFAIANSAEAGDAGVHLVSGWQIFQSTPTEEVPFWADVVLG 115
Query: 122 SLEKFQQQDSNLPAGVTFGCSYETWCLNAPLYLLFLYDQVMKKSEQQNVNIRVKRIKLEK 181
+ + + P V FG ++ T P YL +L ++ K S + R++
Sbjct: 116 FRKMTEAELKKFPQYV-FGQAFTTLKCECPAYLPWLEKRI-KGSGGWTLTRRIE------ 167
Query: 182 LKDICELYPDVNIVVNASGCGLQWEGGLDPKCFLVRGQTLLLDVGDKHDTIPYAHATITH 241
D+ EL+P +IVVN SG G + G D K F VRGQ L + P+ + H
Sbjct: 168 --DLWELHPSFDIVVNCSGLGSRQLAG-DSKIFPVRGQVLQVQA-------PW----VEH 213
Query: 242 QAKSGDWTFVIKRPGKNGKKAYYILGGTKQPGDYSVMPRDTDTEKLIGRGKKLFPELLEN 301
+ G I PG + + LGGT+Q GD+++ P ++ +++ R L P L
Sbjct: 214 FIRDGSGLTYIY-PGTS----HVTLGGTRQKGDWNLSPDAENSREILSRCCALEPSLHGA 268
Query: 302 FEIKNVNVGFRPLRVGGSRVELEFNKSPDGEQMPVIHAYGLGGMGFETSMGVAYHIQKL 360
I+ VG RP R G R++ E + DG+++PV+H YG G G G A +L
Sbjct: 269 CNIRE-KVGLRPYRPG-VRLQTEL-LARDGQRLPVVHHYGHGSGGISVHWGTALEAARL 324
>Hs5231298 [E] KOG3923 D-aspartate oxidase
Length = 282
Score = 75.1 bits (183), Expect = 2e-13
Identities = 59/180 (32%), Positives = 90/180 (49%), Gaps = 20/180 (11%)
Query: 181 KLKDICELYPDVNIVVNASGCGLQWEGGLDPKCFLVRGQTLLLDVGDKHDTIPYAHATIT 240
+++D+ EL+P +IVVN SG G + G D K F VRGQ L + P+ +
Sbjct: 106 RIEDLWELHPSFDIVVNCSGLGSRQLAG-DSKIFPVRGQVLQVQA-------PW----VE 153
Query: 241 HQAKSGDWTFVIKRPGKNGKKAYYILGGTKQPGDYSVMPRDTDTEKLIGRGKKLFPELLE 300
H + G I PG + + LGGT+Q GD+++ P ++ +++ R L P L
Sbjct: 154 HFIRDGSGLTYIY-PGTS----HVTLGGTRQKGDWNLSPDAENSREILSRCCALEPSLHG 208
Query: 301 NFEIKNVNVGFRPLRVGGSRVELEFNKSPDGEQMPVIHAYGLGGMGFETSMGVAYHIQKL 360
I+ VG RP R G R++ E + DG+++PV+H YG G G G A +L
Sbjct: 209 ACNIRE-KVGLRPYRPG-VRLQTEL-LARDGQRLPVVHHYGHGSGGISVHWGTALEAARL 265
>Hs21536470 [E] KOG3923 D-aspartate oxidase
Length = 347
Score = 63.2 bits (152), Expect = 6e-10
Identities = 92/379 (24%), Positives = 159/379 (41%), Gaps = 49/379 (12%)
Query: 1 MSVCIVGAGVIGLSSALRLLETRPDIRTITIVSEQFPQDQPINHTFTSPWAGAHFRPFPH 60
M V ++GAGVIGLS+AL + E + + + P+ T+ A ++P+
Sbjct: 1 MRVVVIGAGVIGLSTALCIHERYHSVLQPLHIKVYADRFTPLT---TTDVAAGLWQPYL- 56
Query: 61 RDSDYASDKRESEYTRVTYNYFKRKSKQWLSEATVEFM-NGIDW----LENPSIEYQRLG 115
SD ++ +E+++++ T++Y +E F+ +G + + +PS + LG
Sbjct: 57 --SD-PNNPQEADWSQQTFDYLLSHVHSPNAENLGLFLISGYNLFHEAIPDPSWKDTVLG 113
Query: 116 AGYNGSSLEKFQQQDSNLPAGVTFGCSYETWCLNAPLYLLFLYDQVMKKSEQQNVNIRVK 175
K ++ ++ +G + + L YL +L +++ ++ ++
Sbjct: 114 -------FRKLTPRELDMFPDYGYGWFHTSLILEGKNYLQWLTERLTERG------VKFF 160
Query: 176 RIKLEKLKDICELYPDVNIVVNASGCGLQWEGGL--DPKCFLVRGQTLLLDVGDKHDTIP 233
+ K+E +++ DV +VN +G W G L DP RGQ + +D P
Sbjct: 161 QRKVESFEEVAREGADV--IVNCTGV---WAGALQRDPLLQPGRGQIMKVDA-------P 208
Query: 234 YA-HATITHQAKSGDWTFVIKRPGKNGKKAYYILGGTKQPGDYSVMPRDTDTEKLIGRGK 292
+ H +TH + G + PG LGG Q G++S + D I G
Sbjct: 209 WMKHFILTHDPERGIYNSPYIIPGTQT----VTLGGIFQLGNWSELNNIQD-HNTIWEGC 263
Query: 293 KLFPELLENFEIKNVNVGFRPLRVGGSRVELEFNKSPDG-EQMPVIHAYGLGGMGFETSM 351
L+N I GFRP+R ++ LE + G VIH YG GG G
Sbjct: 264 CRLEPTLKNARIIGERTGFRPVR---PQIRLEREQLRTGPSNTEVIHNYGHGGYGLTIHW 320
Query: 352 GVAYHIQKLYNNVFSTSKL 370
G A KL+ + KL
Sbjct: 321 GCALEAAKLFGRILEEKKL 339
>HsM4503255 [E] KOG3923 D-aspartate oxidase
Length = 347
Score = 62.4 bits (150), Expect = 1e-09
Identities = 92/379 (24%), Positives = 159/379 (41%), Gaps = 49/379 (12%)
Query: 1 MSVCIVGAGVIGLSSALRLLETRPDIRTITIVSEQFPQDQPINHTFTSPWAGAHFRPFPH 60
M V ++GAGVIGLS+AL + E + + + P+ T+ A ++P+
Sbjct: 1 MRVVVIGAGVIGLSTALCIHERYHSVLQPLHIKVYADRFTPLT---TTDVAAGLWQPYL- 56
Query: 61 RDSDYASDKRESEYTRVTYNYFKRKSKQWLSEATVEFM-NGIDW----LENPSIEYQRLG 115
SD ++ +E+++++ T++Y +E F+ +G + + +PS + LG
Sbjct: 57 --SD-PNNPQEADWSQQTFDYLLSHVHSPNAENLGLFLISGYNLFHEAIPDPSWKDTVLG 113
Query: 116 AGYNGSSLEKFQQQDSNLPAGVTFGCSYETWCLNAPLYLLFLYDQVMKKSEQQNVNIRVK 175
K ++ ++ +G + + L YL +L +++ ++ ++
Sbjct: 114 -------FRKLTPRELDMFPDYGYGWFHTSLILEGKNYLQWLTERLTERG------VKFF 160
Query: 176 RIKLEKLKDICELYPDVNIVVNASGCGLQWEGGL--DPKCFLVRGQTLLLDVGDKHDTIP 233
+ K+E +++ DV +VN +G W G L DP RGQ + +D P
Sbjct: 161 QRKVESFEEVAREGADV--IVNCTGV---WAGALQRDPLLQPGRGQIMKVDA-------P 208
Query: 234 YA-HATITHQAKSGDWTFVIKRPGKNGKKAYYILGGTKQPGDYSVMPRDTDTEKLIGRGK 292
+ H +TH + G + PG LGG Q G++S + D I G
Sbjct: 209 WMKHFILTHDPERGIYNSPYIIPGTQT----VTLGGIFQLGNWSELNNIQD-HNTIWEGC 263
Query: 293 KLFPELLENFEIKNVNVGFRPLRVGGSRVELEFNKSPDG-EQMPVIHAYGLGGMGFETSM 351
L+N I GFRP+R ++ LE + G VIH YG GG G
Sbjct: 264 CRLEPTLKNARIIGEATGFRPVR---PQIRLEREQLRTGPSNTEVIHNYGHGGYGLTIHW 320
Query: 352 GVAYHIQKLYNNVFSTSKL 370
G A KL+ + KL
Sbjct: 321 GCALEAAKLFGRILEEKKL 339
>CE15718 [E] KOG3923 D-aspartate oxidase
Length = 343
Score = 60.5 bits (145), Expect = 4e-09
Identities = 93/384 (24%), Positives = 154/384 (39%), Gaps = 61/384 (15%)
Query: 3 VCIVGAGVIGLSSALRLLETRPDIRTITIVSEQFPQDQPINHTFTSPWAGAHFRPFPHRD 62
+ I+G GVIG S+AL++ + PD R +T++S D+P T + AG FR
Sbjct: 5 IAIIGEGVIGCSTALQVAQAVPDAR-VTVLS-----DRPFEQTCSFGPAGL-FR------ 51
Query: 63 SDYASDKRESEYTRVTYNYFKRKSKQWLSEAT-VEFMNG-IDWLENPSIEYQRLGAG--- 117
D E+ + T+++F + + T V+ ++G I +E Q+ G
Sbjct: 52 ---IDDIANREFGKSTFDWFAHLHRTEKGDKTGVKLLSGHIQSDSKERLEQQQKAYGDIV 108
Query: 118 YNGSSLEKFQQQDSNLPAGVTFGCSYETWCLNAPLYLLFLYDQVMKKSEQQNVNIRVKRI 177
YN LEK + D P Y + Y+ +L Q + +
Sbjct: 109 YNFRFLEKREILDL-FPNPSEHCIHYTAFASEGNKYVPYLKFQCQARGVE---------F 158
Query: 178 KLEKLKDICELYPD-VNIVVNASGCGLQWEGGLDPKCFLVRGQTLLLDVGDKHDTIPYAH 236
K++D+ EL + +++VN +G G D + +RG L D + H
Sbjct: 159 LHRKVRDLEELANEGYDVIVNCAGLSGGTLAGDDDSVYPIRGVVL--------DVEAHWH 210
Query: 237 ATITHQAKSGDW-TFVIKRPGKNGKKAYYILGGTKQPGDYSVMPRDTDTEKLIGRGKKLF 295
++ D+ TF I K+ ++G KQ + + D D + ++ R L
Sbjct: 211 KHFNYK----DFITFTIP------KENSVVIGSVKQENRWDLEITDVDRKDILERYVALH 260
Query: 296 PELLENFEIKNVNVGFRPLRVGGSRVELEFNKSPDGEQMPV---------IHAYGLGGMG 346
P + E +I G RP R ++E G++ V +H YG GG G
Sbjct: 261 PAMREP-KILGEWSGLRPARKTIRIEKVEKKSEKSGKKYTVSSKKKGKNVVHHYGHGGNG 319
Query: 347 FETSMGVAYHIQKLYNNVFSTSKL 370
F G A KL + ++SKL
Sbjct: 320 FTLGWGTAVEATKLVKSALNSSKL 343
>CE07083 [E] KOG3923 D-aspartate oxidase
Length = 334
Score = 60.1 bits (144), Expect = 5e-09
Identities = 93/368 (25%), Positives = 154/368 (41%), Gaps = 58/368 (15%)
Query: 3 VCIVGAGVIGLSSALRLLETRPDIRTITIVSEQFPQDQPINHTFTSPWAGAHFRPFPHRD 62
+ I+G GVIG +SAL++ + P+ + IT++ D+P + ++ AG FR
Sbjct: 8 IAIIGEGVIGCTSALQISKAIPNAK-ITVL-----HDKPFKKSCSAGPAGL-FR------ 54
Query: 63 SDYASDKRESEYTRVTYNYFK---RKSKQWLSEATVEFMNGIDWLEN-PSIEYQRLGAG- 117
DY + +EY R ++ +F R +K SE V+ ++G +N S++ Q+ G
Sbjct: 55 IDY---EENTEYGRASFAWFSHLYRTTKG--SETGVKLVSGHIQSDNLESLKQQQRAYGD 109
Query: 118 --YNGSSLEKFQQQDSNLPAGVTFGCSYETWCLNAPLYLLFLYDQVMKKSEQQNVNIRVK 175
YN L+ ++ D P Y + Y+ +L + ++++ I K
Sbjct: 110 IVYNFRFLDDRERLDI-FPEPSKHCIHYTAYASEGNKYVPYLKNLLLEQ------KIEFK 162
Query: 176 RIKLEKLKDICELYPDVNIVVNASGCGLQWEGGLDPKCFLVRGQTLLLDVGDKHDTIPYA 235
+ ++ L + + DV +VN +G G D C+ +RG L +D H Y
Sbjct: 163 QQEVTSLDAVADAGYDV--IVNCAGLYGGKLAGDDDTCYPIRGVILEVD-APWHKHFNYR 219
Query: 236 HATITHQAKSGDWTFVIKRPGKNGKKAYYILGGTKQPGDYSVMPRDTDTEKLIGRGKKLF 295
T TF I K+ ++G TKQ + + D D ++ R L
Sbjct: 220 DFT----------TFTIP------KEHSVVVGSTKQDNRWDLEITDEDRNDILKRYIALH 263
Query: 296 PELLENFEIKNVNVGFRPLRVGGSRVELEFNKSP---DGEQMPVIHAYGLGGMGFETSMG 352
P + E IK + LR G V +E K + + V+H YG G GF G
Sbjct: 264 PGMREPKIIKE----WSALRPGRKHVRIEAQKRTSVGNSKDYMVVHHYGHGSNGFTLGWG 319
Query: 353 VAYHIQKL 360
A KL
Sbjct: 320 TAIEATKL 327
>CE26739 [E] KOG3923 D-aspartate oxidase
Length = 502
Score = 57.4 bits (137), Expect = 3e-08
Identities = 84/367 (22%), Positives = 142/367 (37%), Gaps = 51/367 (13%)
Query: 3 VCIVGAGVIGLSSALRLLETRPDIRTITIVSEQFPQDQPINHTFTSPWAGAHFRPFPHRD 62
+ ++GAG+ G++SAL + E P+ +TI++E+F + TS A PF D
Sbjct: 4 IAVLGAGINGIASALAIQERLPNCE-VTIIAEKFSPNT------TSDVAAGLIEPFLCDD 56
Query: 63 SDYASDKRESEYTRVTYNYFKRKSKQWLSEATVEFMNGIDWLENPSIEYQRLGAGYNGSS 122
R +T T + + Q E +G WL++ E + L N
Sbjct: 57 ----DVDRIINWTSATIS--RIHEYQADGNPGAEEQSGY-WLQSVKSEPKWLKLMKNVHI 109
Query: 123 LEKFQQQDSNLPAGVTFGCSYETWCLNAPLYLLFLYDQVMKKSEQQNVNIRVKRIKLEKL 182
L + + FG Y TW L Y+ + D+ +K + K+ K+E +
Sbjct: 110 LTDAEMKQVARRPEHKFGIFYTTWYLEPTPYIKWCTDKFLKNGG------KFKKQKIENI 163
Query: 183 KDICELYPDVNIVVNASGCGLQWEGGLDPKCFLVRGQTLLLDVGDKHDTIPYAHATITHQ 242
D+ Y ++ VN +G G + G D + + RGQ L + + + +
Sbjct: 164 DDVARSY---DVTVNCTGLGSRALIG-DKEVYPTRGQILKVSC----PRVKHFFIDDKYY 215
Query: 243 AKSGDWTFVIKRPGKNGKKAYYILGGTKQPGDYSVMPRDTDTEKLIGRGKKLFPELLENF 302
A D T LGGT + + + ++K++ P L
Sbjct: 216 ALLNDSTIT--------------LGGTFEAHQWDLTINSELSQKILKENIHNIPS-LRTA 260
Query: 303 EIKNVNVGFRPLRVGGSRVELEFNKSPDGEQMPVIHAYGLGGMGFETSMGVAYHIQKLYN 362
+I + +V R R G R++ E +S ++H YG GG G G A ++
Sbjct: 261 QILSSHVDMRXSR-GTVRLQAELGRS-------LVHNYGHGGSGITLHWGCALECAEIVE 312
Query: 363 NVFSTSK 369
NV K
Sbjct: 313 NVLKMKK 319
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.319 0.138 0.421
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,244,563
Number of Sequences: 60738
Number of extensions: 1123145
Number of successful extensions: 2309
Number of sequences better than 1.0e-05: 8
Number of HSP's better than 0.0 without gapping: 0
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 2286
Number of HSP's gapped (non-prelim): 9
length of query: 370
length of database: 30,389,216
effective HSP length: 108
effective length of query: 262
effective length of database: 23,829,512
effective search space: 6243332144
effective search space used: 6243332144
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)