ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIV1974 check: MH R KOG0605 General function prediction only NDR and related serine/threonine kinases
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIV1974 gi|401646|sp|P31034|YL44_KLULA Hypothetical 31.8
kDa protein in L44/L41 3'region
(762 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YNL161w [R] KOG0605 NDR and related serine/threonine kinases 822 0.0
SPAC821.12 [R] KOG0605 NDR and related serine/threonine kinases 608 e-173
Hs18579683 [R] KOG0605 NDR and related serine/threonine kinases 439 e-123
CE28760 [R] KOG0605 NDR and related serine/threonine kinases 432 e-121
Hs6005814 [R] KOG0605 NDR and related serine/threonine kinases 422 e-117
7293735 [R] KOG0605 NDR and related serine/threonine kinases 417 e-116
At3g23310 [R] KOG0605 NDR and related serine/threonine kinases 396 e-110
At2g20470 [R] KOG0605 NDR and related serine/threonine kinases 386 e-107
At1g30640 [R] KOG0605 NDR and related serine/threonine kinases 384 e-106
At1g03920 [R] KOG0605 NDR and related serine/threonine kinases 381 e-105
At4g33080 [R] KOG0605 NDR and related serine/threonine kinases 379 e-105
At2g19400 [R] KOG0605 NDR and related serine/threonine kinases 375 e-103
At4g14350 [R] KOG0605 NDR and related serine/threonine kinases 369 e-101
At5g09890 [R] KOG0605 NDR and related serine/threonine kinases 364 e-100
Hs18959200 [D] KOG0608 Warts/lats-like serine threonine kinases 362 2e-99
Hs4758666 [D] KOG0608 Warts/lats-like serine threonine kinases 347 4e-95
7301980 [D] KOG0608 Warts/lats-like serine threonine kinases 343 6e-94
CE13844 [D] KOG0608 Warts/lats-like serine threonine kinases 318 1e-86
At5g62310 [TR] KOG0606 Microtubule-associated serine/threonine k... 244 4e-64
SPCC417.06c [R] KOG0605 NDR and related serine/threonine kinases 243 6e-64
SPAC24B11.11c [R] KOG0605 NDR and related serine/threonine kinases 241 4e-63
At1g48490 [TR] KOG0606 Microtubule-associated serine/threonine k... 241 4e-63
At3g17850 [TR] KOG0606 Microtubule-associated serine/threonine k... 237 6e-62
At1g45160 [TR] KOG0606 Microtubule-associated serine/threonine k... 231 3e-60
CE20493 [TR] KOG0606 Microtubule-associated serine/threonine kin... 223 7e-58
YGR092w [R] KOG0605 NDR and related serine/threonine kinases 222 2e-57
YPR111w [R] KOG0605 NDR and related serine/threonine kinases 218 2e-56
YNR047w [R] KOG0610 Putative serine/threonine protein kinase 215 2e-55
SPAC4G8.05 [R] KOG0610 Putative serine/threonine protein kinase 207 6e-53
At3g12690 [R] KOG0610 Putative serine/threonine protein kinase 194 4e-49
At1g79250 [R] KOG0610 Putative serine/threonine protein kinase 194 4e-49
At5g55910 [R] KOG0610 Putative serine/threonine protein kinase 189 1e-47
At5g03640 [R] KOG0610 Putative serine/threonine protein kinase 187 5e-47
At1g16440 [R] KOG0610 Putative serine/threonine protein kinase 186 1e-46
At3g52890 [R] KOG0610 Putative serine/threonine protein kinase 184 6e-46
At2g44830 [R] KOG0610 Putative serine/threonine protein kinase 183 1e-45
At2g36350 [R] KOG0610 Putative serine/threonine protein kinase 180 8e-45
At5g40030 [R] KOG0610 Putative serine/threonine protein kinase 179 2e-44
Hs4885583 [T] KOG0612 Rho-associated coiled-coil containing prot... 176 9e-44
Hs4759044 [T] KOG0612 Rho-associated coiled-coil containing prot... 172 2e-42
Hs20536595 [T] KOG0612 Rho-associated coiled-coil containing pro... 172 2e-42
Hs16357474_1 [T] KOG0612 Rho-associated coiled-coil containing p... 167 7e-41
Hs10334852 [T] KOG0612 Rho-associated coiled-coil containing pro... 163 8e-40
CE11916 [T] KOG0612 Rho-associated coiled-coil containing protei... 163 8e-40
Hs4505831 [T] KOG0612 Rho-associated coiled-coil containing prot... 162 1e-39
SPBC725.06c [R] KOG0605 NDR and related serine/threonine kinases 162 2e-39
CE08098 [T] KOG0612 Rho-associated coiled-coil containing protei... 160 9e-39
At3g14370 [R] KOG0610 Putative serine/threonine protein kinase 160 9e-39
7291742_1 [T] KOG0612 Rho-associated coiled-coil containing prot... 159 2e-38
At3g20830 [R] KOG0610 Putative serine/threonine protein kinase 157 8e-38
At2g34650 [R] KOG0610 Putative serine/threonine protein kinase 157 8e-38
7293249 [T] KOG0612 Rho-associated coiled-coil containing protei... 156 1e-37
At3g08720 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 155 2e-37
At3g08730 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 155 3e-37
SPAC22E12.14c [RT] KOG0598 Ribosomal protein S6 kinase and relat... 153 1e-36
7294566 [T] KOG0612 Rho-associated coiled-coil containing protei... 152 1e-36
At3g44610 [R] KOG0610 Putative serine/threonine protein kinase 152 2e-36
At3g25250 [R] KOG0610 Putative serine/threonine protein kinase 150 7e-36
7291910 [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 150 7e-36
At1g53700 [R] KOG0610 Putative serine/threonine protein kinase 150 9e-36
YMR104c [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 147 5e-35
Hs7657526 [T] KOG0603 Ribosomal protein S6 kinase 147 5e-35
CE18169 [T] KOG0603 Ribosomal protein S6 kinase 147 5e-35
CE13014 [T] KOG0603 Ribosomal protein S6 kinase 147 5e-35
Hs4759050 [T] KOG0603 Ribosomal protein S6 kinase 147 6e-35
Hs20149547 [T] KOG0603 Ribosomal protein S6 kinase 147 6e-35
SPCC1450.11c [R] KOG0605 NDR and related serine/threonine kinases 147 8e-35
Hs14249562 [TR] KOG0606 Microtubule-associated serine/threonine ... 147 8e-35
7294265 [TR] KOG0606 Microtubule-associated serine/threonine kin... 146 1e-34
Hs19923570 [T] KOG0603 Ribosomal protein S6 kinase 146 1e-34
At4g13000 [R] KOG0610 Putative serine/threonine protein kinase 146 1e-34
7300437 [TR] KOG0606 Microtubule-associated serine/threonine kin... 146 1e-34
YKL126w [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 145 2e-34
YDR466w [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 145 3e-34
At1g51170 [R] KOG0610 Putative serine/threonine protein kinase 144 7e-34
7295426 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 144 7e-34
CE22045 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 143 9e-34
Hs4885549 [T] KOG0690 Serine/threonine protein kinase 142 2e-33
SPCC24B10.07 [RT] KOG0598 Ribosomal protein S6 kinase and relate... 139 1e-32
SPAC1B9.02c [RT] KOG0598 Ribosomal protein S6 kinase and related... 139 2e-32
Hs17455844 [TR] KOG0606 Microtubule-associated serine/threonine ... 138 3e-32
Hs15619015 [T] KOG0616 cAMP-dependent protein kinase catalytic s... 138 3e-32
YHR205w [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 138 4e-32
7294770 [T] KOG0603 Ribosomal protein S6 kinase 138 4e-32
Hs14149671 [TR] KOG0606 Microtubule-associated serine/threonine ... 137 5e-32
7300106 [T] KOG0690 Serine/threonine protein kinase 137 5e-32
YFL033c [R] KOG0605 NDR and related serine/threonine kinases 137 6e-32
YDR490c [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 137 6e-32
SPCC4G3.08 [RT] KOG0598 Ribosomal protein S6 kinase and related ... 137 6e-32
7295638 [T] KOG0603 Ribosomal protein S6 kinase 137 8e-32
Hs8923754 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 136 1e-31
CE15475 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 136 1e-31
CE15473 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 136 1e-31
Hs4506739 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 135 2e-31
Hs20543401 [TR] KOG0606 Microtubule-associated serine/threonine ... 135 2e-31
Hs4506055 [T] KOG0616 cAMP-dependent protein kinase catalytic su... 135 2e-31
ECU01g1320 [T] KOG0612 Rho-associated coiled-coil containing pro... 135 2e-31
Hs4759052 [T] KOG0603 Ribosomal protein S6 kinase 135 3e-31
YCR091w [R] KOG0610 Putative serine/threonine protein kinase 134 4e-31
Hs20070247_2 [RT] KOG0598 Ribosomal protein S6 kinase and relate... 134 5e-31
7297542 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 134 7e-31
Hs4502023 [T] KOG0690 Serine/threonine protein kinase 133 9e-31
Hs4506737 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 133 1e-30
CE14798 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 133 1e-30
CE28744 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 132 2e-30
YKL166c [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 132 3e-30
At3g10540 [T] KOG0592 3-phosphoinositide-dependent protein kinas... 132 3e-30
YPL203w [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 130 8e-30
Hs20127541 [RT] KOG0598 Ribosomal protein S6 kinase and related ... 130 1e-29
At5g04510 [T] KOG0592 3-phosphoinositide-dependent protein kinas... 130 1e-29
Hs4506057 [T] KOG0616 cAMP-dependent protein kinase catalytic su... 129 1e-29
CE15612 [T] KOG0690 Serine/threonine protein kinase 129 2e-29
Hs4885061 [T] KOG0690 Serine/threonine protein kinase 128 3e-29
Hs4506735 [T] KOG0603 Ribosomal protein S6 kinase 128 4e-29
YJL164c [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 127 5e-29
Hs10835242 [T] KOG0614 cGMP-dependent protein kinase 127 5e-29
CE04603 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 127 5e-29
CE17354 [T] KOG0694 Serine/threonine protein kinase 127 8e-29
CE17353 [T] KOG0694 Serine/threonine protein kinase 127 8e-29
CE29298 [T] KOG0690 Serine/threonine protein kinase 126 1e-28
CE18646 [T] KOG0690 Serine/threonine protein kinase 126 1e-28
CE03492 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 126 1e-28
SPBC1861.09 [R] KOG0610 Putative serine/threonine protein kinase 126 1e-28
Hs5032091 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 125 3e-28
CE28739 [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 124 7e-28
SPBC106.10 [T] KOG0616 cAMP-dependent protein kinase catalytic s... 123 9e-28
7301734 [T] KOG0694 Serine/threonine protein kinase 123 9e-28
CE05507 [T] KOG0603 Ribosomal protein S6 kinase 123 1e-27
Hs4885563 [T] KOG0694 Serine/threonine protein kinase 122 2e-27
CE29092 [T] KOG0694 Serine/threonine protein kinase 122 2e-27
CE28740 [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 122 2e-27
Hs7019489 [T] KOG0694 Serine/threonine protein kinase 122 3e-27
7302861 [T] KOG0696 Serine/threonine protein kinase 121 3e-27
7301971 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 121 5e-27
Hs4826948 [T] KOG0616 cAMP-dependent protein kinase catalytic su... 120 8e-27
Hs20535816 [T] KOG0695 Serine/threonine protein kinase 120 8e-27
Hs10864650 [T] KOG0695 Serine/threonine protein kinase 120 8e-27
CE02604 [T] KOG0695 Serine/threonine protein kinase 120 8e-27
7302860 [T] KOG0696 Serine/threonine protein kinase 120 1e-26
Hs4505695 [T] KOG0592 3-phosphoinositide-dependent protein kinas... 119 1e-26
Hs5453972 [T] KOG0694 Serine/threonine protein kinase 119 2e-26
Hs22043324 [T] KOG0603 Ribosomal protein S6 kinase 119 2e-26
YBR028c [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 119 2e-26
Hs4506071 [T] KOG0695 Serine/threonine protein kinase 119 2e-26
7303111 [T] KOG0695 Serine/threonine protein kinase 119 2e-26
YOL100w [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 118 3e-26
CE05274 [T] KOG0690 Serine/threonine protein kinase 117 5e-26
CE02074 [T] KOG0986 G protein-coupled receptor kinase 116 1e-25
At5g47750 [R] KOG0610 Putative serine/threonine protein kinase 116 1e-25
At3g27580 [R] KOG0610 Putative serine/threonine protein kinase 116 1e-25
Hs10835065 [T] KOG0616 cAMP-dependent protein kinase catalytic s... 116 1e-25
Hs4506067 [T] KOG0696 Serine/threonine protein kinase 115 2e-25
Hs4501971 [T] KOG0986 G protein-coupled receptor kinase 115 2e-25
At4g26610 [R] KOG0610 Putative serine/threonine protein kinase 115 3e-25
Hs21450709 [RT] KOG0598 Ribosomal protein S6 kinase and related ... 114 4e-25
CE02586 [T] KOG0696 Serine/threonine protein kinase 114 6e-25
7301972 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 114 6e-25
SPAC17G8.14c [T] KOG0694 Serine/threonine protein kinase 113 1e-24
At2g26700_2 [R] KOG0610 Putative serine/threonine protein kinase 113 1e-24
Hs5453978 [T] KOG0614 cGMP-dependent protein kinase 112 2e-24
CE03979 [T] KOG0614 cGMP-dependent protein kinase 112 3e-24
Hs4885055 [T] KOG0986 G protein-coupled receptor kinase 111 4e-24
Hs14759411 [TR] KOG0606 Microtubule-associated serine/threonine ... 111 4e-24
SPBC4C3.11 [T] KOG0592 3-phosphoinositide-dependent protein kina... 110 8e-24
Hs22068916 [T] KOG0696 Serine/threonine protein kinase 110 1e-23
Hs20127450 [T] KOG0696 Serine/threonine protein kinase 110 1e-23
SPBC12D12.04c [T] KOG0694 Serine/threonine protein kinase 109 1e-23
7296166 [T] KOG0614 cGMP-dependent protein kinase 109 1e-23
Hs5453976 [T] KOG0694 Serine/threonine protein kinase 108 2e-23
Hs21166359 [T] KOG0986 G protein-coupled receptor kinase 108 2e-23
SPCC320.12c [D] KOG0580 Serine/threonine protein kinase 108 3e-23
Hs13384594 [T] KOG0696 Serine/threonine protein kinase 108 3e-23
7303915 [T] KOG0694 Serine/threonine protein kinase 107 5e-23
7303914 [T] KOG0694 Serine/threonine protein kinase 107 5e-23
Hs4506073 [T] KOG0694 Serine/threonine protein kinase 107 7e-23
Hs14758219 [T] KOG0694 Serine/threonine protein kinase 107 7e-23
YBL105c [T] KOG0694 Serine/threonine protein kinase 107 9e-23
7302050 [T] KOG0986 G protein-coupled receptor kinase 106 1e-22
Hs5453974 [T] KOG0694 Serine/threonine protein kinase 105 2e-22
Hs14735945 [T] KOG0694 Serine/threonine protein kinase 103 8e-22
CE07156 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 103 8e-22
CE27166 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 103 1e-21
CE19898 [T] KOG0614 cGMP-dependent protein kinase 103 1e-21
CE19897 [T] KOG0614 cGMP-dependent protein kinase 103 1e-21
Hs22066167 [RT] KOG0598 Ribosomal protein S6 kinase and related ... 103 1e-21
Hs7662170 [R] KOG0611 Predicted serine/threonine protein kinase 102 3e-21
Hs5453970 [T] KOG0694 Serine/threonine protein kinase 102 3e-21
CE18699 [T] KOG0694 Serine/threonine protein kinase 102 3e-21
CE01554 [T] KOG0986 G protein-coupled receptor kinase 102 3e-21
Hs4885349 [T] KOG0986 G protein-coupled receptor kinase 101 5e-21
7299322 [R] KOG0611 Predicted serine/threonine protein kinase 101 5e-21
Hs4885347 [T] KOG0986 G protein-coupled receptor kinase 100 6e-21
Hs4504101 [T] KOG0986 G protein-coupled receptor kinase 100 6e-21
ECU07g0520 [T] KOG0616 cAMP-dependent protein kinase catalytic s... 100 6e-21
Hs4506529 [T] KOG0986 G protein-coupled receptor kinase 100 1e-20
Hs13569922 [R] KOG0611 Predicted serine/threonine protein kinase 100 1e-20
At4g24400 [T] KOG0583 Serine/threonine protein kinase 100 1e-20
7297611 [T] KOG0614 cGMP-dependent protein kinase 99 2e-20
Hs4507275 [D] KOG0580 Serine/threonine protein kinase 99 3e-20
SPCC162.10 [RT] KOG0598 Ribosomal protein S6 kinase and related ... 98 4e-20
Hs4507273 [D] KOG0580 Serine/threonine protein kinase 98 4e-20
CE20142 [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 98 4e-20
Hs4759178 [D] KOG0580 Serine/threonine protein kinase 98 5e-20
CE24761 [D] KOG0580 Serine/threonine protein kinase 98 5e-20
YPL209c [D] KOG0580 Serine/threonine protein kinase 97 7e-20
At5g45810 [T] KOG0583 Serine/threonine protein kinase 97 9e-20
7293512 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 97 9e-20
At1g29230 [T] KOG0583 Serine/threonine protein kinase 97 1e-19
At4g18700 [T] KOG0583 Serine/threonine protein kinase 95 4e-19
YPL153c [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 95 5e-19
At5g35410 [T] KOG0583 Serine/threonine protein kinase 95 5e-19
At2g26980 [T] KOG0583 Serine/threonine protein kinase 94 8e-19
At2g30360 [T] KOG0583 Serine/threonine protein kinase 94 1e-18
SPCC576.15c [T] KOG0592 3-phosphoinositide-dependent protein kin... 93 1e-18
Hs20547806 [R] KOG0589 Serine/threonine protein kinase 93 1e-18
At4g32830 [D] KOG0580 Serine/threonine protein kinase 93 1e-18
At5g25110 [T] KOG0583 Serine/threonine protein kinase 93 2e-18
SPCC18B5.11c [D] KOG0615 Serine/threonine protein kinase Chk2 an... 92 2e-18
At1g54960 [T] KOG0198 MEKK and related serine/threonine protein ... 92 2e-18
HsM7657627 [D] KOG0575 Polo-like serine/threonine protein kinase 92 3e-18
At2g25880 [D] KOG0580 Serine/threonine protein kinase 92 3e-18
At1g12680 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 92 4e-18
At4g30960 [T] KOG0583 Serine/threonine protein kinase 91 5e-18
At3g06030 [T] KOG0198 MEKK and related serine/threonine protein ... 91 5e-18
At1g09000 [T] KOG0198 MEKK and related serine/threonine protein ... 91 7e-18
CE21879 [D] KOG0590 Checkpoint kinase and related serine/threoni... 91 9e-18
At2g34180 [T] KOG0583 Serine/threonine protein kinase 91 9e-18
At3g29160 [T] KOG0583 Serine/threonine protein kinase 90 1e-17
At1g30270 [T] KOG0583 Serine/threonine protein kinase 90 1e-17
7302464 [R] KOG0586 Serine/threonine protein kinase 90 1e-17
7290249 [R] KOG0586 Serine/threonine protein kinase 90 1e-17
At5g56580 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 89 2e-17
Hs9966875 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 89 3e-17
Hs21361433 [D] KOG0575 Polo-like serine/threonine protein kinase 89 3e-17
At2g20040 [T] KOG0616 cAMP-dependent protein kinase catalytic su... 89 3e-17
CE27768 [R] KOG0586 Serine/threonine protein kinase 88 4e-17
CE23838 [R] KOG0586 Serine/threonine protein kinase 88 4e-17
At3g01090 [T] KOG0583 Serine/threonine protein kinase 88 4e-17
Hs20545245 [D] KOG0588 Serine/threonine protein kinase 88 6e-17
Hs14754789 [OUT] KOG0595 Serine/threonine-protein kinase involve... 88 6e-17
At4g29810 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 88 6e-17
7298652 [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 88 6e-17
SPAC57A10.02 [D] KOG0588 Serine/threonine protein kinase 87 7e-17
Hs14196445 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 87 7e-17
At4g14580 [T] KOG0583 Serine/threonine protein kinase 87 7e-17
Hs21389411 [T] KOG0694 Serine/threonine protein kinase 87 1e-16
At5g39440 [T] KOG0583 Serine/threonine protein kinase 87 1e-16
At5g19360 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 87 1e-16
At5g12180 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 87 1e-16
At3g15220 [T] KOG0201 Serine/threonine protein kinase 87 1e-16
At2g45490 [D] KOG0580 Serine/threonine protein kinase 87 1e-16
YNR031c [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and r... 87 1e-16
At2g25090 [T] KOG0583 Serine/threonine protein kinase 87 1e-16
7299536 [D] KOG0580 Serine/threonine protein kinase 87 1e-16
YMR001c [D] KOG0575 Polo-like serine/threonine protein kinase 86 2e-16
Hs4502553 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 86 2e-16
YDR477w [T] KOG0583 Serine/threonine protein kinase 86 2e-16
Hs7661974 [T] KOG0583 Serine/threonine protein kinase 86 2e-16
CE28218 [D] KOG0588 Serine/threonine protein kinase 86 2e-16
CE21025 [D] KOG0580 Serine/threonine protein kinase 86 2e-16
7294217 [D] KOG0588 Serine/threonine protein kinase 86 2e-16
At5g45820 [T] KOG0583 Serine/threonine protein kinase 86 3e-16
At5g01810 [T] KOG0583 Serine/threonine protein kinase 86 3e-16
SPBC1D7.05c [T] KOG0198 MEKK and related serine/threonine protei... 85 4e-16
HsM4507279 [D] KOG0580 Serine/threonine protein kinase 85 4e-16
Hs9845489 [R] KOG0586 Serine/threonine protein kinase 85 4e-16
Hs9845487 [R] KOG0586 Serine/threonine protein kinase 85 4e-16
Hs22062450 [R] KOG0586 Serine/threonine protein kinase 85 4e-16
CE17284 [T] KOG0583 Serine/threonine protein kinase 85 4e-16
At1g01140 [T] KOG0583 Serine/threonine protein kinase 85 4e-16
7299437 [R] KOG0586 Serine/threonine protein kinase 85 4e-16
ECU07g0360 [D] KOG0580 Serine/threonine protein kinase 85 5e-16
CE25046 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 84 6e-16
At5g07070 [T] KOG0583 Serine/threonine protein kinase 84 6e-16
At5g01820 [T] KOG0583 Serine/threonine protein kinase 84 6e-16
At4g26070 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 84 6e-16
At4g04720 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 84 6e-16
At2g38490 [T] KOG0583 Serine/threonine protein kinase 84 8e-16
7304283 [Z] KOG0613 Projectin/twitchin and related proteins 84 8e-16
Hs7661994 [T] KOG0579 Ste20-like serine/threonine protein kinase 84 1e-15
7290150 [T] KOG0583 Serine/threonine protein kinase 84 1e-15
SPCC1259.13 [D] KOG0590 Checkpoint kinase and related serine/thr... 83 1e-15
HsM4505103 [R] KOG0586 Serine/threonine protein kinase 83 1e-15
Hs6005850 [D] KOG0615 Serine/threonine protein kinase Chk2 and r... 83 1e-15
Hs13899225 [R] KOG0586 Serine/threonine protein kinase 83 1e-15
At5g10930 [T] KOG0583 Serine/threonine protein kinase 83 2e-15
At2g41860 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 83 2e-15
Hs5174701 [T] KOG0579 Ste20-like serine/threonine protein kinase 82 2e-15
Hs22045207 [T] KOG0986 G protein-coupled receptor kinase 82 2e-15
SPBC21.06c [T] KOG0198 MEKK and related serine/threonine protein... 82 3e-15
Hs20070158 [T] KOG0201 Serine/threonine protein kinase 82 3e-15
At4g21940 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 82 3e-15
At3g17510 [T] KOG0583 Serine/threonine protein kinase 82 3e-15
YHR102w [T] KOG0201 Serine/threonine protein kinase 82 4e-15
CE26793_1 [R] KOG0611 Predicted serine/threonine protein kinase 82 4e-15
SPAC9G1.02 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 an... 81 5e-15
SPAC1F3.02c [T] KOG0198 MEKK and related serine/threonine protei... 81 5e-15
HsM8923212 [T] KOG4717 Serine/threonine protein kinase 81 5e-15
Hs5454096 [T] KOG0574 STE20-like serine/threonine kinase MST 81 5e-15
Hs17933758 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase ... 81 5e-15
At3g20410 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 81 5e-15
At1g12580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 81 5e-15
Hs8923922 [R] KOG0586 Serine/threonine protein kinase 81 7e-15
Hs18596354 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 81 7e-15
Hs14728804 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 81 7e-15
At1g53165 [T] KOG0201 Serine/threonine protein kinase 81 7e-15
7304311 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 81 7e-15
SPCC74.03c [T] KOG0583 Serine/threonine protein kinase 80 9e-15
At5g58380 [T] KOG0583 Serine/threonine protein kinase 80 9e-15
At2g38910 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 80 9e-15
At1g53570 [T] KOG0198 MEKK and related serine/threonine protein ... 80 9e-15
YCL024w [T] KOG0583 Serine/threonine protein kinase 80 2e-14
SPBC19C2.05 [T] KOG0583 Serine/threonine protein kinase 80 2e-14
Hs15011880 [T] KOG0201 Serine/threonine protein kinase 80 2e-14
CE00847 [T] KOG0583 Serine/threonine protein kinase 80 2e-14
At1g32320 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 80 2e-14
At1g49180_1 [OUT] KOG0595 Serine/threonine-protein kinase involv... 80 2e-14
SPAC2C4.14c [T] KOG0201 Serine/threonine protein kinase 79 2e-14
HsM5454174 [T] KOG0201 Serine/threonine protein kinase 79 2e-14
Hs21361358 [T] KOG0201 Serine/threonine protein kinase 79 2e-14
At3g23000 [T] KOG0583 Serine/threonine protein kinase 79 2e-14
At1g50700 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 79 2e-14
7300224 [T] KOG0201 Serine/threonine protein kinase 79 2e-14
SPAC23C11.16 [D] KOG0575 Polo-like serine/threonine protein kinase 79 3e-14
Hs5453966 [T] KOG0583 Serine/threonine protein kinase 79 3e-14
CE22877 [D] KOG0575 Polo-like serine/threonine protein kinase 79 3e-14
At5g57630 [T] KOG0583 Serine/threonine protein kinase 79 3e-14
At5g19450 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 79 3e-14
At4g38230 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 79 3e-14
At3g57530 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 79 3e-14
7297080 [T] KOG0583 Serine/threonine protein kinase 79 3e-14
Hs4758128_2 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase... 79 3e-14
Hs4505153 [T] KOG0198 MEKK and related serine/threonine protein ... 79 3e-14
CE28479 [T] KOG0583 Serine/threonine protein kinase 79 3e-14
At5g23580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 79 3e-14
YCR073c [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and r... 78 4e-14
Hs5454094 [T] KOG0574 STE20-like serine/threonine kinase MST 78 4e-14
Hs16178962 [T] KOG0574 STE20-like serine/threonine kinase MST 78 4e-14
At4g35310 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 78 4e-14
SPCC297.03 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase ... 78 6e-14
Hs21361643 [T] KOG4717 Serine/threonine protein kinase 78 6e-14
Hs14150045 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase ... 78 6e-14
At1g63700 [T] KOG0198 MEKK and related serine/threonine protein ... 78 6e-14
7299438 [R] KOG0586 Serine/threonine protein kinase 78 6e-14
Hs5453964 [T] KOG0583 Serine/threonine protein kinase 77 8e-14
Hs4505785 [G] KOG0599 Phosphorylase kinase gamma subunit 77 8e-14
CE28643 [T] KOG0583 Serine/threonine protein kinase 77 8e-14
CE07458 [T] KOG0583 Serine/threonine protein kinase 77 8e-14
CE05780 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 77 8e-14
At4g09570 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 77 8e-14
At4g04740 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 77 8e-14
At1g35670 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 77 8e-14
7293247 [T] KOG0578 p21-activated serine/threonine protein kinase 77 8e-14
Hs6005922_2 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase... 77 8e-14
Hs19311016_1 [R] KOG0589 Serine/threonine protein kinase 77 8e-14
YFR014c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 77 1e-13
YAR019c [T] KOG0198 MEKK and related serine/threonine protein ki... 77 1e-13
Hs7706549 [D] KOG0600 Cdc2-related protein kinase 77 1e-13
CE28674 [T] KOG0201 Serine/threonine protein kinase 77 1e-13
CE12408 [T] KOG0661 MAPK related serine/threonine protein kinase 77 1e-13
CE07510 [T] KOG0201 Serine/threonine protein kinase 77 1e-13
At3g10660 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 77 1e-13
7292679 [G] KOG0599 Phosphorylase kinase gamma subunit 77 1e-13
At2g35890 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 77 1e-13
At2g17290 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 77 1e-13
At1g76040 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 77 1e-13
At1g48260 [T] KOG0583 Serine/threonine protein kinase 77 1e-13
7304358 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 77 1e-13
HsM5729922 [T] KOG0198 MEKK and related serine/threonine protein... 76 2e-13
Hs7657214 [T] KOG0583 Serine/threonine protein kinase 76 2e-13
Hs4502803 [D] KOG0590 Checkpoint kinase and related serine/threo... 76 2e-13
CE28061 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 76 2e-13
CE28060 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 76 2e-13
CE28059 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 76 2e-13
CE28058 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 76 2e-13
CE28057 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 76 2e-13
CE28056 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 76 2e-13
CE28055 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 76 2e-13
CE28054 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 76 2e-13
CE28053 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 76 2e-13
CE28051 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 76 2e-13
At5g04870 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 76 2e-13
At1g18350 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 76 2e-13
7293666 [D] KOG0575 Polo-like serine/threonine protein kinase 76 2e-13
Hs4758192 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 76 2e-13
Hs13489054 [T] KOG0581 Mitogen-activated protein kinase kinase (... 76 2e-13
At4g23650 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 76 2e-13
At1g50230 [R] KOG0597 Serine-threonine protein kinase FUSED 76 2e-13
Hs4502709 [R] KOG0594 Protein kinase PCTAIRE and related kinases 75 3e-13
Hs14141724 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase ... 75 3e-13
ECU08g1790 [D] KOG0600 Cdc2-related protein kinase 75 3e-13
At3g20860 [R] KOG0589 Serine/threonine protein kinase 75 3e-13
7298926 [T] KOG0578 p21-activated serine/threonine protein kinase 75 3e-13
Hs4505397 [T] KOG0198 MEKK and related serine/threonine protein ... 75 4e-13
Hs21735556 [T] KOG0198 MEKK and related serine/threonine protein... 75 4e-13
7300650 [R] KOG0594 Protein kinase PCTAIRE and related kinases 75 4e-13
Hs15451902 [T] KOG0576 Mitogen-activated protein kinase kinase k... 75 5e-13
At4g10010 [D] KOG0600 Cdc2-related protein kinase 75 5e-13
At1g69220 [T] KOG0576 Mitogen-activated protein kinase kinase ki... 75 5e-13
At1g61950 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 75 5e-13
YCR008w [D] KOG0590 Checkpoint kinase and related serine/threoni... 74 6e-13
Hs20127418 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase ... 74 6e-13
YDR507c [D] KOG0588 Serine/threonine protein kinase 74 8e-13
YBR274w [D] KOG0590 Checkpoint kinase and related serine/threoni... 74 8e-13
Hs22068996 [T] KOG1345 Serine/threonine kinase 74 8e-13
Hs11496279 [T] KOG0661 MAPK related serine/threonine protein kinase 74 8e-13
ECU01g0630 [D] KOG0575 Polo-like serine/threonine protein kinase 74 8e-13
At4g04700 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 74 8e-13
7303211 [T] KOG4717 Serine/threonine protein kinase 74 8e-13
7302570 [R] KOG0586 Serine/threonine protein kinase 74 8e-13
7293496 [R] KOG0597 Serine-threonine protein kinase FUSED 74 8e-13
At3g05050 [D] KOG0600 Cdc2-related protein kinase 74 1e-12
7302511 [T] KOG0576 Mitogen-activated protein kinase kinase kina... 74 1e-12
YLR362w [T] KOG0198 MEKK and related serine/threonine protein ki... 73 1e-12
SPACUNK12.02c [T] KOG0032 Ca2+/calmodulin-dependent protein kina... 73 1e-12
Hs7706286 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase E... 73 1e-12
Hs7382496 [T] KOG0578 p21-activated serine/threonine protein kinase 73 1e-12
Hs5730055 [D] KOG0575 Polo-like serine/threonine protein kinase 73 1e-12
Hs5453882 [G] KOG0599 Phosphorylase kinase gamma subunit 73 1e-12
Hs4505373 [V] KOG1826 Ras GTPase activating protein RasGAP/neuro... 73 1e-12
CE26076 [D] KOG0590 Checkpoint kinase and related serine/threoni... 73 1e-12
At5g66210 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 73 1e-12
At4g40010 [T] KOG0583 Serine/threonine protein kinase 73 1e-12
At3g07980 [T] KOG0198 MEKK and related serine/threonine protein ... 73 1e-12
7297009 [R] KOG0593 Predicted protein kinase KKIAMRE 73 1e-12
Hs5579478 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 73 2e-12
Hs5031975 [T] KOG0578 p21-activated serine/threonine protein kinase 73 2e-12
Hs14110390 [D] KOG0600 Cdc2-related protein kinase 73 2e-12
Hs14110387 [D] KOG0600 Cdc2-related protein kinase 73 2e-12
CE20636 [D] KOG0590 Checkpoint kinase and related serine/threoni... 73 2e-12
CE09360 [Z] KOG0613 Projectin/twitchin and related proteins 73 2e-12
CE02377 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 73 2e-12
At3g61960 [OUT] KOG0595 Serine/threonine-protein kinase involved... 73 2e-12
At1g73500 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 73 2e-12
7296450 [D] KOG0575 Polo-like serine/threonine protein kinase 73 2e-12
7291778 [T] KOG0579 Ste20-like serine/threonine protein kinase 73 2e-12
7290841 [D] KOG0591 NIMA (never in mitosis)-related G2-specific ... 73 2e-12
YJL095w [T] KOG0198 MEKK and related serine/threonine protein ki... 72 2e-12
YHL007c [T] KOG0578 p21-activated serine/threonine protein kinase 72 2e-12
Hs21359873 [D] KOG0575 Polo-like serine/threonine protein kinase 72 2e-12
CE23001 [R] KOG0589 Serine/threonine protein kinase 72 2e-12
CE03584 [T] KOG0607 MAP kinase-interacting kinase and related se... 72 2e-12
SPBC8D2.19 [T] KOG0661 MAPK related serine/threonine protein kinase 72 3e-12
Hs7705551 [T] KOG0661 MAPK related serine/threonine protein kinase 72 3e-12
Hs21361133 [R] KOG0586 Serine/threonine protein kinase 72 3e-12
Hs14771959 [T] KOG0578 p21-activated serine/threonine protein ki... 72 3e-12
7290147 [T] KOG0583 Serine/threonine protein kinase 72 3e-12
Hs9910476 [T] KOG0578 p21-activated serine/threonine protein kinase 72 4e-12
CE28251 [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 72 4e-12
CE10328 [T] KOG1006 Mitogen-activated protein kinase (MAPK) kina... 72 4e-12
At4g08500 [T] KOG0198 MEKK and related serine/threonine protein ... 72 4e-12
At1g33770 [D] KOG0600 Cdc2-related protein kinase 72 4e-12
SPCC63.08c [OUT] KOG0595 Serine/threonine-protein kinase involve... 71 5e-12
CE01146 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kin... 71 5e-12
Hs4507277_1 [R] KOG0589 Serine/threonine protein kinase 71 5e-12
YOL016c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 71 7e-12
YGL179c [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kin... 71 7e-12
SPAC23H4.02 [T] KOG0583 Serine/threonine protein kinase 71 7e-12
HsM4826916 [D] KOG0575 Polo-like serine/threonine protein kinase 71 7e-12
Hs4758016 [D] KOG0575 Polo-like serine/threonine protein kinase 71 7e-12
Hs14770402 [R] KOG0586 Serine/threonine protein kinase 71 7e-12
CE07599 [T] KOG0576 Mitogen-activated protein kinase kinase kina... 71 7e-12
At3g13530 [T] KOG0198 MEKK and related serine/threonine protein ... 71 7e-12
7299160 [OUT] KOG0595 Serine/threonine-protein kinase involved i... 71 7e-12
Hs7662388 [T] KOG0661 MAPK related serine/threonine protein kinase 70 9e-12
Hs4505601 [T] KOG0578 p21-activated serine/threonine protein kinase 70 9e-12
Hs22065405 [RT] KOG0598 Ribosomal protein S6 kinase and related ... 70 9e-12
Hs8393810_1 [T] KOG0587 Traf2- and Nck-interacting kinase and re... 70 9e-12
Hs20544910_1 [T] KOG0587 Traf2- and Nck-interacting kinase and r... 70 9e-12
YPL140c [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K) 70 1e-11
Hs4557511 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 70 1e-11
Hs4557439 [R] KOG0594 Protein kinase PCTAIRE and related kinases 70 1e-11
CE21401 [G] KOG0658 Glycogen synthase kinase-3 70 1e-11
CE21086 [D] KOG0590 Checkpoint kinase and related serine/threoni... 70 1e-11
7302458 [T] KOG0574 STE20-like serine/threonine kinase MST 70 1e-11
HsM4758928 [D] KOG0601 Cyclin-dependent kinase WEE1 70 2e-11
Hs4505599 [T] KOG0578 p21-activated serine/threonine protein kinase 70 2e-11
Hs21361083 [D] KOG0601 Cyclin-dependent kinase WEE1 70 2e-11
Hs20479818 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 70 2e-11
CE12478 [D] KOG0590 Checkpoint kinase and related serine/threoni... 70 2e-11
CE06635 [Z] KOG0613 Projectin/twitchin and related proteins 70 2e-11
CE06634 [Z] KOG0613 Projectin/twitchin and related proteins 70 2e-11
At4g36070 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 70 2e-11
At2g31500 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 70 2e-11
At1g54610 [D] KOG0600 Cdc2-related protein kinase 70 2e-11
At1g03740 [D] KOG0600 Cdc2-related protein kinase 70 2e-11
7298323 [D] KOG0590 Checkpoint kinase and related serine/threoni... 70 2e-11
7291043 [T] KOG0660 Mitogen-activated protein kinase 70 2e-11
Hs4502567_1 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase... 70 2e-11
CE12518 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 69 2e-11
At3g04530 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 69 2e-11
At1g78290 [T] KOG0583 Serine/threonine protein kinase 69 2e-11
At1g08650 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 69 2e-11
SPBC32C12.03c [T] KOG0583 Serine/threonine protein kinase 69 3e-11
SPAC29A4.16 [D] KOG0590 Checkpoint kinase and related serine/thr... 69 3e-11
Hs22057171 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 69 3e-11
Hs22035600 [T] KOG0576 Mitogen-activated protein kinase kinase k... 69 3e-11
Hs18552621 [R] KOG0597 Serine-threonine protein kinase FUSED 69 3e-11
Hs16950621 [Z] KOG0613 Projectin/twitchin and related proteins 69 3e-11
Hs16950617 [Z] KOG0613 Projectin/twitchin and related proteins 69 3e-11
>YNL161w [R] KOG0605 NDR and related serine/threonine kinases
Length = 756
Score = 822 bits (2123), Expect = 0.0
Identities = 409/510 (80%), Positives = 432/510 (84%), Gaps = 13/510 (2%)
Query: 254 NGSANNYMYFERRPDLLTKTTQDKAAAVKLKIENFYQSSVGYAIERNQRRLELESELASQ 313
NG+ +NYMYFERRPDLLTK TQDKAAAVKLKIENFYQSSV YAIERN+RR+ELE+EL S
Sbjct: 259 NGTISNYMYFERRPDLLTKGTQDKAAAVKLKIENFYQSSVKYAIERNERRVELETELTSH 318
Query: 314 DWSEERKNRQLASLGKKESQFXXXXXXXXXXDDFNSVKVIGKGAFGEVRLVQKKDTGKIY 373
+WSEERK+RQL+SLGKKESQF +DF++VKVIGKGAFGEVRLVQKKDTGKIY
Sbjct: 319 NWSEERKSRQLSSLGKKESQFLRLRRTRLSLEDFHTVKVIGKGAFGEVRLVQKKDTGKIY 378
Query: 374 AMKTLLKSEMYNKDQLAHVKAERDVLAGSDSPWVVSLYYSFQDSQYLYLIMEFLPGGDLM 433
AMKTLLKSEMY KDQLAHVKAERDVLAGSDSPWVVSLYYSFQD+QYLYLIMEFLPGGDLM
Sbjct: 379 AMKTLLKSEMYKKDQLAHVKAERDVLAGSDSPWVVSLYYSFQDAQYLYLIMEFLPGGDLM 438
Query: 434 TMLIRWQIFTEDVTRFYMAECILAIEVIHKLGFIHRDIKPDNILIDIRGHIKLSDFGLST 493
TMLIRWQ+FTEDVTRFYMAECILAIE IHKLGFIHRDIKPDNILIDIRGHIKLSDFGLST
Sbjct: 439 TMLIRWQLFTEDVTRFYMAECILAIETIHKLGFIHRDIKPDNILIDIRGHIKLSDFGLST 498
Query: 494 GFHKTHDSSYYXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPNETNNGN-RNTMLVDAIHL 552
GFHKTHDS+YY N T+ N R TM+VD+I L
Sbjct: 499 GFHKTHDSNYYKKLLQQDEATNGISKPGTYNA---------NTTDTANKRQTMVVDSISL 549
Query: 553 TMTNRQQMQTWRKSRRLMAYSTVGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWP 612
TM+NRQQ+QTWRKSRRLMAYSTVGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWP
Sbjct: 550 TMSNRQQIQTWRKSRRLMAYSTVGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWP 609
Query: 613 PFCSETPQETYRKIMNFEQTLQFPDDIHISYEAEDLIRRLLTHSENRLGRHGGADEIKAH 672
PFCSETPQETYRKIMNFEQTLQFPDDIHISYEAEDLIRRLLTH++ RLGRHGGADEIK+H
Sbjct: 610 PFCSETPQETYRKIMNFEQTLQFPDDIHISYEAEDLIRRLLTHADQRLGRHGGADEIKSH 669
Query: 673 PFFSGVDWNTIRQVEAPYIPKLSSVTDTRFFPTDELENVPDSPXXXXXXXXXXXXXXXXX 732
PFF GVDWNTIRQVEAPYIPKLSS+TDTRFFPTDELENVPDSP
Sbjct: 670 PFFRGVDWNTIRQVEAPYIPKLSSITDTRFFPTDELENVPDSPAMAQAAKQREQMTKQGG 729
Query: 733 GVPQSNAKEDLPFIGYTYSRFDYLTRKNAL 762
P KEDLPFIGYTYSRFDYLTRKNAL
Sbjct: 730 SAP---VKEDLPFIGYTYSRFDYLTRKNAL 756
Score = 70.1 bits (170), Expect = 1e-11
Identities = 50/127 (39%), Positives = 58/127 (45%), Gaps = 38/127 (29%)
Query: 63 NDFQQQGNMPFSEPSQPMFSTNYMKQQGSQPSLQDRLTXXXXXXXXXXXXYYPNGGFTDV 122
N +QQ P FS+NYMK+QGS SLQ+ L GFTDV
Sbjct: 40 NPYQQ-----IPRPPAAGFSSNYMKEQGSHQSLQEHLQRETGNL---------GSGFTDV 85
Query: 123 PNLNYPATPPPTQS-----------------IYSHNNNSNSKVYQ-----SAQ--HTSPG 158
P LNYPATPPP + +Y HNNNS S V +AQ SPG
Sbjct: 86 PALNYPATPPPHNNYAASNQMINTPPPSMGGLYRHNNNSQSMVQNGNGSGNAQLPQLSPG 145
Query: 159 QYSVASE 165
QYS+ SE
Sbjct: 146 QYSIESE 152
>SPAC821.12 [R] KOG0605 NDR and related serine/threonine kinases
Length = 469
Score = 608 bits (1567), Expect = e-173
Identities = 302/505 (59%), Positives = 369/505 (72%), Gaps = 39/505 (7%)
Query: 258 NNYMYFERRPDLLTKTTQDKAAAVKLKIENFYQSSVGYAIERNQRRLELESELASQDWSE 317
N+Y++FER P L K+T DK K IE++Y+ +V +A+ERNQRR+ LE LA++ SE
Sbjct: 4 NDYLHFERNPSLFPKSTLDKVQKTKKYIEHYYKVAVDHAVERNQRRINLEQRLATERGSE 63
Query: 318 ERKNRQLASLGKKESQFXXXXXXXXXXDDFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKT 377
ERKNRQL + G+KESQF +DF+++KVIGKGAFGEVRLVQK DTGKIYAMK+
Sbjct: 64 ERKNRQLRASGEKESQFLRFRRTRLSLEDFSTIKVIGKGAFGEVRLVQKLDTGKIYAMKS 123
Query: 378 LLKSEMYNKDQLAHVKAERDVLAGSDSPWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLI 437
LLK+EM+ +DQLAHVKAERD+L SDSPWVVSLYY+FQDS YLYLIMEFLPGGDLMTMLI
Sbjct: 124 LLKTEMFKRDQLAHVKAERDLLVESDSPWVVSLYYAFQDSLYLYLIMEFLPGGDLMTMLI 183
Query: 438 RWQIFTEDVTRFYMAECILAIEVIHKLGFIHRDIKPDNILIDIRGHIKLSDFGLSTGFHK 497
+ F+EDVTRFYMAEC+LAI +H++G+IHRDIKPDNILID GHIKLSDFGLSTGF+K
Sbjct: 184 NYDTFSEDVTRFYMAECVLAIADVHRMGYIHRDIKPDNILIDRDGHIKLSDFGLSTGFYK 243
Query: 498 THDSSYYXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPNETNNGNRNTMLVDAIHLTMTNR 557
S+ Y T N + +VDAI LTM+++
Sbjct: 244 QDQSASY----------------------------MKPRTGNTVKRGQMVDAIWLTMSSK 275
Query: 558 QQMQTWRKSRRLMAYSTVGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSE 617
+M TW+K+RR+MAYSTVGTPDYIAPEIFL QGYGQ+CDWWSLGAIM+ECLIGWPPFCSE
Sbjct: 276 DKMATWKKNRRVMAYSTVGTPDYIAPEIFLQQGYGQDCDWWSLGAIMFECLIGWPPFCSE 335
Query: 618 TPQETYRKIMNFEQTLQFPDDIHISYEAEDLIRRLLTHSENRLGRHGGADEIKAHPFFSG 677
ETYRKI+N+ +TL FP+DIH+S EA DL+ RL+T SE+RLGR GGA EI HPFF+G
Sbjct: 336 NSHETYRKIINWRETLTFPNDIHLSIEARDLMDRLMTDSEHRLGR-GGAIEIMQHPFFTG 394
Query: 678 VDWNTIRQVEAPYIPKLSSVTDTRFFPTDELENVPDSPXXXXXXXXXXXXXXXXXGVPQS 737
+DW+ IR+ AP+IP L S+TDT +FP DELE VP+ P PQ+
Sbjct: 395 IDWDHIRETAAPFIPNLKSITDTHYFPVDELEQVPEQPVTQQPASVD----------PQT 444
Query: 738 NAKEDLPFIGYTYSRFDYLTRKNAL 762
+ +L F+GYTY +F+YLT K AL
Sbjct: 445 LEQTNLAFLGYTYKKFNYLTMKGAL 469
>Hs18579683 [R] KOG0605 NDR and related serine/threonine kinases
Length = 464
Score = 439 bits (1130), Expect = e-123
Identities = 228/497 (45%), Positives = 315/497 (62%), Gaps = 58/497 (11%)
Query: 270 LTKTTQDKAAAVKLKIENFYQSSVGYAIERNQRRLELESELASQDWSEERKNRQLASLGK 329
++ T+++ KL +ENFY + + ER R+ +LE + + ++E K + + +
Sbjct: 13 MSNHTRERVTVAKLTLENFYSNLILQHEERETRQKKLEVAMEEEGLADEEKKLRRSQHAR 72
Query: 330 KESQFXXXXXXXXXXDDFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQL 389
KE++F DDF S+KVIG+GAFGEVRLVQKKDTG IYAMK L KS+M K+Q+
Sbjct: 73 KETEFLRLKRTRLGLDDFESLKVIGRGAFGEVRLVQKKDTGHIYAMKILRKSDMLEKEQV 132
Query: 390 AHVKAERDVLAGSDSPWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRF 449
AH++AERD+L +D WVV ++YSFQD + LYLIMEFLPGGD+MT+L++ TE+ T+F
Sbjct: 133 AHIRAERDILVEADGAWVVKMFYSFQDKRNLYLIMEFLPGGDMMTLLMKKDTLTEEETQF 192
Query: 450 YMAECILAIEVIHKLGFIHRDIKPDNILIDIRGHIKLSDFGLSTGFHKTHDSSYYXXXXX 509
Y++E +LAI+ IH+LGFIHRDIKPDN+L+D +GH+KLSDFGL TG K H + +Y
Sbjct: 193 YISETVLAIDAIHQLGFIHRDIKPDNLLLDAKGHVKLSDFGLCTGLKKAHRTEFYR---- 248
Query: 510 XXXXXXXXXXXXXXXXXXXXXXXXPNETNNGNRNTMLVDAIHLTMTNRQQMQTWRKSRRL 569
N T+N D M ++++ +TW+K+RR
Sbjct: 249 -------------------------NLTHNPPS-----DFSFQNMNSKRKAETWKKNRRQ 278
Query: 570 MAYSTVGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNF 629
+AYSTVGTPDYIAPE+F+ GY + CDWWSLG IMYE LIG+PPFCSETPQETYRK+MN+
Sbjct: 279 LAYSTVGTPDYIAPEVFMQTGYNKLCDWWSLGVIMYEMLIGYPPFCSETPQETYRKVMNW 338
Query: 630 EQTLQFPDDIHISYEAEDLIRRLLTHSENRLGRHGGADEIKAHPFFSGVDWNTIRQVEAP 689
++TL FP ++ IS +A+DLI R SENR+G + G +EIK HPFF GVDW IR+ A
Sbjct: 339 KETLVFPPEVPISEKAKDLILRFCIDSENRIG-NSGVEEIKGHPFFEGVDWEHIRERPAA 397
Query: 690 YIPKLSSVTDTRFF----PTDELENVPDSPXXXXXXXXXXXXXXXXXGVPQSNAKEDLPF 745
++ S+ DT F +D L+ VP++ P +K D F
Sbjct: 398 IPIEIKSIDDTSNFDDFPESDILQPVPNTTE------------------PDYKSK-DWVF 438
Query: 746 IGYTYSRFDYLTRKNAL 762
+ YTY RF+ LT++ ++
Sbjct: 439 LNYTYKRFEGLTQRGSI 455
>CE28760 [R] KOG0605 NDR and related serine/threonine kinases
Length = 467
Score = 432 bits (1111), Expect = e-121
Identities = 224/490 (45%), Positives = 296/490 (59%), Gaps = 48/490 (9%)
Query: 270 LTKTTQDKAAAVKLKIENFYQSSVGYAIERNQRRLELESELASQDWSEERKNRQLASLGK 329
+++ T+DKA+ ++ IE++Y V ER R +LE +++++ S+E K +
Sbjct: 3 ISQYTKDKASCTRISIESYYSKRVTQCAERENRLKKLEEDISARGLSDEEKEEKRKIHHS 62
Query: 330 KESQFXXXXXXXXXXDDFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQL 389
KE+ + +DF S+KVIG+GAFGEVRLVQK DTG IYAMK L KSEM K+Q
Sbjct: 63 KETDYLRLKRTRLTVNDFESLKVIGRGAFGEVRLVQKHDTGHIYAMKILRKSEMVEKEQT 122
Query: 390 AHVKAERDVLAGSDSPWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRF 449
AHV+AERD+L+ +D WVV +YYSFQD LYL+MEFLPGGD+MT+LI+ TE+ T+F
Sbjct: 123 AHVRAERDILSEADCDWVVKMYYSFQDYSNLYLVMEFLPGGDMMTLLIKKDTLTEEATQF 182
Query: 450 YMAECILAIEVIHKLGFIHRDIKPDNILIDIRGHIKLSDFGLSTGFHKTHDSSYYXXXXX 509
Y+AE LAI+ IH LGFIHRDIKPDN+L+D RGH+KLSDFGL TG K H + +Y
Sbjct: 183 YIAEAALAIQFIHSLGFIHRDIKPDNLLLDARGHVKLSDFGLCTGLKKFHRTDHY----- 237
Query: 510 XXXXXXXXXXXXXXXXXXXXXXXXPNETNNGNRNTMLVDAIHLTMTNRQQMQTWRKSRRL 569
+T+ D I ++++ +TW+++RR
Sbjct: 238 -----------------------------RNWPSTLPPDFISKPFESKRKAETWKRNRRA 268
Query: 570 MAYSTVGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNF 629
AYSTVGTPDYIAPE+F GY + CDWWSLG IMYE LIG+PPFCSE PQETYRK++N+
Sbjct: 269 YAYSTVGTPDYIAPEVFQPNGYTKSCDWWSLGVIMYEMLIGYPPFCSELPQETYRKVINW 328
Query: 630 EQTLQFPDDIHISYEAEDLIRRLLTHSENRLGRHGGADEIKAHPFFSGVDWNTIRQVEAP 689
+QTL FP D+ IS EA+ I+R +E RLG HGG DEIK PF +DWN IR+ P
Sbjct: 329 QQTLVFPSDVPISIEAKATIKRFCCEAERRLGNHGGLDEIKQCPFVKRIDWNHIRERPPP 388
Query: 690 YIPKLSSVTDTRFFPTDELENVPDSPXXXXXXXXXXXXXXXXXGVPQSNAKEDLPFIGYT 749
+ S+ DT F ++ PD P+ F+ +T
Sbjct: 389 IRVTVKSIDDTSNF-----DDFPDEDLTWPTSTLIR---------PEEQPGRRGEFVDFT 434
Query: 750 YSRFDYLTRK 759
Y RFD LT+K
Sbjct: 435 YKRFDGLTQK 444
>Hs6005814 [R] KOG0605 NDR and related serine/threonine kinases
Length = 465
Score = 422 bits (1084), Expect = e-117
Identities = 215/494 (43%), Positives = 309/494 (62%), Gaps = 49/494 (9%)
Query: 270 LTKTTQDKAAAVKLKIENFYQSSVGYAIERNQRRLELESELASQDWSEERKNRQLASLGK 329
++ T+++ K+ +ENFY + + ER R+ +LE + + +E K + ++ +
Sbjct: 12 MSNHTKERVTMTKVTLENFYSNLIAQHEEREMRQKKLEKVMEEEGLKDEEKRLRRSAHAR 71
Query: 330 KESQFXXXXXXXXXXDDFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQL 389
KE++F +DF S+KVIG+GAFGEVRLVQKKDTG +YAMK L K++M K+Q+
Sbjct: 72 KETEFLRLKRTRLGLEDFESLKVIGRGAFGEVRLVQKKDTGHVYAMKILRKADMLEKEQV 131
Query: 390 AHVKAERDVLAGSDSPWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRF 449
H++AERD+L +DS WVV ++YSFQD LYLIMEFLPGGD+MT+L++ TE+ T+F
Sbjct: 132 GHIRAERDILVEADSLWVVKMFYSFQDKLNLYLIMEFLPGGDMMTLLMKKDTLTEEETQF 191
Query: 450 YMAECILAIEVIHKLGFIHRDIKPDNILIDIRGHIKLSDFGLSTGFHKTHDSSYYXXXXX 509
Y+AE +LAI+ IH+LGFIHRDIKPDN+L+D +GH+KLSDFGL TG K H + +Y
Sbjct: 192 YIAETVLAIDSIHQLGFIHRDIKPDNLLLDSKGHVKLSDFGLCTGLKKAHRTEFY----- 246
Query: 510 XXXXXXXXXXXXXXXXXXXXXXXXPNETNNGNRNTMLVDAIHLTMTNRQQMQTWRKSRRL 569
+++ D M ++++ +TW+++RR
Sbjct: 247 -----------------------------RNLNHSLPSDFTFQNMNSKRKAETWKRNRRQ 277
Query: 570 MAYSTVGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNF 629
+A+STVGTPDYIAPE+F+ GY + CDWWSLG IMYE LIG+PPFCSETPQETY+K+MN+
Sbjct: 278 LAFSTVGTPDYIAPEVFMQTGYNKLCDWWSLGVIMYEMLIGYPPFCSETPQETYKKVMNW 337
Query: 630 EQTLQFPDDIHISYEAEDLIRRLLTHSENRLGRHGGADEIKAHPFFSGVDWNTIRQVEAP 689
++TL FP ++ IS +A+DLI R E+R+G G +EIK++ FF GVDW IR+ A
Sbjct: 338 KETLTFPPEVPISEKAKDLILRFCCEWEHRIGA-PGVEEIKSNSFFEGVDWEHIRERPAA 396
Query: 690 YIPKLSSVTDTRFFPTDELENVPDSPXXXXXXXXXXXXXXXXXGVPQSNAK-EDLPFIGY 748
++ S+ DT F + P+S P+++ K +D FI Y
Sbjct: 397 ISIEIKSIDDTSNF-----DEFPESDILKPTVATSNH--------PETDYKNKDWVFINY 443
Query: 749 TYSRFDYLTRKNAL 762
TY RF+ LT + A+
Sbjct: 444 TYKRFEGLTARGAI 457
>7293735 [R] KOG0605 NDR and related serine/threonine kinases
Length = 459
Score = 417 bits (1071), Expect = e-116
Identities = 217/485 (44%), Positives = 299/485 (60%), Gaps = 54/485 (11%)
Query: 274 TQDKAAAVKLKIENFYQSSVGYAIERNQRRLELESELASQDWSEERKNRQLASLGKKESQ 333
T DKA K+ +EN+Y + V ER QR +LE++L + SE ++ + +KE++
Sbjct: 20 TLDKATKAKVTLENYYSNLVTQYGERKQRLAKLEAQLKDESLSEAQRQEKRLQHAQKETE 79
Query: 334 FXXXXXXXXXXDDFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVK 393
+ +DF ++KVIG+GAFGEVRLVQKKDTG +YAMK L K++M K+Q+AHV+
Sbjct: 80 YLRLKRLRLGVEDFEALKVIGRGAFGEVRLVQKKDTGHVYAMKVLRKADMLEKEQVAHVR 139
Query: 394 AERDVLAGSDSPWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAE 453
AERDVL +D WVV +YYSFQD LYLIMEFLPGGD+MT+L++ +E+ T+FY++E
Sbjct: 140 AERDVLVEADHQWVVKMYYSFQDPVNLYLIMEFLPGGDMMTLLMKKDTLSEEGTQFYISE 199
Query: 454 CILAIEVIHKLGFIHRDIKPDNILIDIRGHIKLSDFGLSTGFHKTHDSSYYXXXXXXXXX 513
LAI+ IHKLGFIHRDIKPDN+L+D RGH+KLSDFGL TG K+H + +Y
Sbjct: 200 TALAIDSIHKLGFIHRDIKPDNLLLDARGHLKLSDFGLCTGLKKSHRTDFYRDLSQA--- 256
Query: 514 XXXXXXXXXXXXXXXXXXXXPNETNNGNRNTMLVDAIHLTMTNRQQMQTWRKSRRLMAYS 573
+ + + M ++++ ++W+++RR +AYS
Sbjct: 257 ----------------------------KPSDFIGTCASPMDSKRRAESWKRNRRALAYS 288
Query: 574 TVGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTL 633
TVGTPDYIAPE+FL GYG CDWWSLG IMYE L+G+PPFCS+ PQ+TYRK+MN+ +TL
Sbjct: 289 TVGTPDYIAPEVFLQTGYGPACDWWSLGVIMYEMLMGYPPFCSDNPQDTYRKVMNWRETL 348
Query: 634 QFPDDIHISYEAEDLIRRLLTHSENRLGRHGGADEIKAHPFFSGVDWNTIRQVEAPYIPK 693
FP +I IS EA++ I ++ RLG G +++K+ PFF GVDW IR+ A +
Sbjct: 349 IFPPEIPISEEAKETIINFCCEADRRLGSQRGLEDLKSVPFFRGVDWEHIRERPAAIPVE 408
Query: 694 LSSVTDTR---FFPTDELENVPDSPXXXXXXXXXXXXXXXXXGVPQ-SNAKEDLPFIGYT 749
+ S+ DT FP LE +P +P +PQ +D FI YT
Sbjct: 409 VRSIDDTSNFDEFPDVSLE-IPSAP------------------IPQGGEIAKDWVFINYT 449
Query: 750 YSRFD 754
Y RF+
Sbjct: 450 YKRFE 454
>At3g23310 [R] KOG0605 NDR and related serine/threonine kinases
Length = 568
Score = 396 bits (1017), Expect = e-110
Identities = 216/489 (44%), Positives = 299/489 (60%), Gaps = 43/489 (8%)
Query: 268 DLLTKTTQDKAAAVKLKIENFYQSSVGYAIERNQRRLELESELASQDWSEERKNRQLASL 327
+ ++ T+ KAAA K IEN Y+ V +R +RR LE++LA+ + SEE + L L
Sbjct: 41 EAVSNVTKQKAAAAKQYIENHYKKQVQSQQQRKERRDMLENKLAAAEVSEEEQKNLLKDL 100
Query: 328 GKKESQFXXXXXXXXXXDDFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKD 387
KKE+++ DDF + +IGKGAFGEVR+ ++K TG +YAMK L KSEM +
Sbjct: 101 EKKETEYMRRQRHKMGTDDFEPLTMIGKGAFGEVRICREKTTGNVYAMKKLKKSEMLRRG 160
Query: 388 QLAHVKAERDVLAGSDSPWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVT 447
Q+ HVKAER++LA DS +V LY SFQD +YLYLIME+LPGGD+MT+L+R TED
Sbjct: 161 QVEHVKAERNLLAEVDSNCIVKLYCSFQDEEYLYLIMEYLPGGDMMTLLMRKDTLTEDEA 220
Query: 448 RFYMAECILAIEVIHKLGFIHRDIKPDNILIDIRGHIKLSDFGLSTGFHKTHDSSYYXXX 507
RFY+ E +LAIE IHK +IHRDIKPDN+L+D GH+KLSDFGL K D S
Sbjct: 221 RFYVGETVLAIESIHKHNYIHRDIKPDNLLLDRSGHMKLSDFGLC----KPLDCSILQEK 276
Query: 508 XXXXXXXXXXXXXXXXXXXXXXXXXXPNETNNGNRNTMLVDAIHLTMTNRQQMQTWRKSR 567
+ + ++ A T + +Q+Q W+++R
Sbjct: 277 DFVVA----------------------HNLSGALQSDGRPVAPRRTRSQMEQLQNWQRNR 314
Query: 568 RLMAYSTVGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIM 627
R++AYSTVGTPDYIAPE+ L +GYG ECDWWSLGAIMYE L+G+PPF S+ P T RKI+
Sbjct: 315 RMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGAIMYEMLVGFPPFYSDEPMTTCRKIV 374
Query: 628 NFEQTLQFPDDIHISYEAEDLIRRLLTHSENRLGRHGGADEIKAHPFFSGVDWNTIRQVE 687
N++ L+FPD++ +S EA+DLI RLL + E R+G GA+EIK HP+FSGV+W + Q++
Sbjct: 375 NWKNYLKFPDEVRLSPEAKDLICRLLCNVEQRIGTK-GANEIKEHPWFSGVEWEKLYQMK 433
Query: 688 APYIPKLSSVTDTRFFPTDE--LENVPDSPXXXXXXXXXXXXXXXXXGVPQSNAKEDLPF 745
A +IP+++ DT+ F E +P +P + + +D+ F
Sbjct: 434 AAFIPQVNDELDTQNFEKFEEVKTKIPKTPKSGPWR--------------KMLSSKDINF 479
Query: 746 IGYTYSRFD 754
+GYTY +
Sbjct: 480 VGYTYKNVE 488
>At2g20470 [R] KOG0605 NDR and related serine/threonine kinases
Length = 596
Score = 386 bits (992), Expect = e-107
Identities = 215/503 (42%), Positives = 305/503 (59%), Gaps = 48/503 (9%)
Query: 254 NGSANNYMYFERRPDLLTKTTQDKAAAVKLKIENFYQSSVGYAIERNQRRLELESELASQ 313
NGSA+ + E + ++ TT+ K AA K IEN Y+ + ER +RR LE +LA
Sbjct: 32 NGSADEHNV-ETDEEAVSNTTKQKVAAAKQYIENHYKEQMKILQERKERRSMLEQKLADA 90
Query: 314 DWSEERKNRQLASLGKKESQFXXXXXXXXXXDDFNSVKVIGKGAFGEVRLVQKKDTGKIY 373
D SEE +N L L KKE+++ DF+ + +IGKGAFGEVR+ ++K TG++Y
Sbjct: 91 DVSEEDQNNLLKFLEKKETEYMRLQRHKLGVADFDLLTMIGKGAFGEVRVCREKTTGQVY 150
Query: 374 AMKTLLKSEMYNKDQLAHVKAERDVLAGSDSPWVVSLYYSFQDSQYLYLIMEFLPGGDLM 433
AMK L K+EM + Q+ HV+AER++LA DS ++V LY SFQD +LYL+ME+LPGGD+M
Sbjct: 151 AMKKLKKAEMLRRGQVEHVRAERNLLAEVDSNYIVKLYCSFQDDDHLYLVMEYLPGGDMM 210
Query: 434 TMLIRWQIFTEDVTRFYMAECILAIEVIHKLGFIHRDIKPDNILIDIRGHIKLSDFGLST 493
T+L+R TE+ +FY+AE +LAIE IH+ +IHRDIKPDN+L+D GH++LSDFGL
Sbjct: 211 TLLMRKDTLTEEEAKFYVAETVLAIESIHRHNYIHRDIKPDNLLLDRYGHLRLSDFGLC- 269
Query: 494 GFHKTHDSSYYXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPNETNNGNRNT-MLVDAIHL 552
K D S + +NN N +T +
Sbjct: 270 ---KPLDCS---------------------------AIGENDFSNNSNGSTEQEAGSTAP 299
Query: 553 TMTNRQQMQTWRKSRRLMAYSTVGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWP 612
T ++Q++ W+++RR +AYSTVGTPDYIAPE+ L +GYG ECDWWSLGAIMYE L+G+P
Sbjct: 300 KRTQQEQLEHWQRNRRTLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGAIMYEMLVGYP 359
Query: 613 PFCSETPQETYRKIMNFEQTLQFPDDIHISYEAEDLIRRLLTHSENRLGRHGGADEIKAH 672
PF S+ P T RKI+N++ L+FP++ +S EA+DLI LL RLG GADE+KAH
Sbjct: 360 PFYSDDPMSTCRKIVNWKSHLKFPEEAILSREAKDLINSLLCSVRRRLGSK-GADELKAH 418
Query: 673 PFFSGVDWNTIRQVEAPYIPKLSSVTDTRFFPT-DELENVPDSPXXXXXXXXXXXXXXXX 731
+F VDW+TI ++A ++P+++ DT+ F DE E+ +
Sbjct: 419 TWFETVDWDTIFDMDAAFVPEVNDDLDTQNFEKFDESESETQTSSKSGPWR--------- 469
Query: 732 XGVPQSNAKEDLPFIGYTYSRFD 754
+ + +D+ F+GYTY F+
Sbjct: 470 ----KMLSSKDINFVGYTYKNFE 488
>At1g30640 [R] KOG0605 NDR and related serine/threonine kinases
Length = 562
Score = 384 bits (986), Expect = e-106
Identities = 215/502 (42%), Positives = 287/502 (56%), Gaps = 39/502 (7%)
Query: 255 GSANNYMYFERRP--DLLTKTTQDKAAAVKLKIENFYQSSVGYAIERNQRRLELESELAS 312
G N R P D + T+ K AA K IEN Y+ ER +RR LE LA
Sbjct: 26 GQEGNVKNLGRPPMNDAPSNATKQKVAAAKQYIENHYKIQKKSLQERKERRSILEQNLAD 85
Query: 313 QDWSEERKNRQLASLGKKESQFXXXXXXXXXXDDFNSVKVIGKGAFGEVRLVQKKDTGKI 372
D + E K L + KKE ++ DDF + +IG+GAFGEVR+ ++K TG +
Sbjct: 86 ADVTVEDKMDILKNFEKKEMEYMRLQRQKMGVDDFELLSIIGRGAFGEVRICKEKSTGSV 145
Query: 373 YAMKTLLKSEMYNKDQLAHVKAERDVLAGSDSPWVVSLYYSFQDSQYLYLIMEFLPGGDL 432
YAMK L KSEM + Q+ HVKAER+VLA DSP++V L YSFQD ++LYLIME+LPGGD+
Sbjct: 146 YAMKKLKKSEMLRRGQVEHVKAERNVLAEVDSPFIVKLCYSFQDDEHLYLIMEYLPGGDM 205
Query: 433 MTMLIRWQIFTEDVTRFYMAECILAIEVIHKLGFIHRDIKPDNILIDIRGHIKLSDFGLS 492
MT+L+R ED TRFY+A+ ILAIE IHK ++HRDIKPDN+LI GHIKLSDFGLS
Sbjct: 206 MTLLMRKDTLREDETRFYVAQTILAIESIHKHNYVHRDIKPDNLLITRNGHIKLSDFGLS 265
Query: 493 TGFHKTHDSSYYXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPNETNNGNRNTMLVDAIHL 552
+ + P+
Sbjct: 266 KSLESKNFPDF---------KAELVDRSTKPAAEHDRLSKPPSAPRR------------- 303
Query: 553 TMTNRQQMQTWRKSRRLMAYSTVGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWP 612
T ++Q+ W+++RR +A+STVGTPDYIAPE+ L +GYG ECDWWSLGAIM+E L+G+P
Sbjct: 304 --TQQEQLLHWQQNRRTLAFSTVGTPDYIAPEVLLKKGYGMECDWWSLGAIMFEMLVGFP 361
Query: 613 PFCSETPQETYRKIMNFEQTLQFPDDIHISYEAEDLIRRLLTHSENRLGRHGGADEIKAH 672
PF SE P T RKI+N++ L+FPD+ +S E +DLIRRLL + E RLG G EIKAH
Sbjct: 362 PFYSEEPLATCRKIVNWKTCLKFPDEAKLSIEVKDLIRRLLCNVEQRLGTK-GVHEIKAH 420
Query: 673 PFFSGVDWNTIRQVEAPYIPKLSSVTDTRFFPTDELENVPDSPXXXXXXXXXXXXXXXXX 732
P+F GV+W + + APYIP++ DT+ F ++ + VP +
Sbjct: 421 PWFRGVEWERLYESNAPYIPQVKHELDTQNF--EKFDEVPSTCQTSSKSSPWR------- 471
Query: 733 GVPQSNAKEDLPFIGYTYSRFD 754
+ + +D F+GYT+ +
Sbjct: 472 ---KMISSKDANFLGYTFKNLE 490
>At1g03920 [R] KOG0605 NDR and related serine/threonine kinases
Length = 569
Score = 381 bits (979), Expect = e-105
Identities = 209/488 (42%), Positives = 293/488 (59%), Gaps = 44/488 (9%)
Query: 268 DLLTKTTQDKAAAVKLKIENFYQSSVGYAIERNQRRLELESELASQDWSEERKNRQLASL 327
+ L+ +T+ K AA K IEN Y+ + ER +RR LE +LA D EE + + L
Sbjct: 58 EALSNSTKQKVAAAKQYIENHYKEQMKNLNERKERRTTLEKKLADADVCEEDQTNLMKFL 117
Query: 328 GKKESQFXXXXXXXXXXDDFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKD 387
KKE+++ DDF + +IGKGAFGEVR+V++ +TG ++AMK L KSEM +
Sbjct: 118 EKKETEYMRLQRHKMGADDFELLTMIGKGAFGEVRVVREINTGHVFAMKKLKKSEMLRRG 177
Query: 388 QLAHVKAERDVLAGSDSPWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVT 447
Q+ HV+AER++LA DS +V LY SFQD++YLYLIME+LPGGD+MT+L+R +ED
Sbjct: 178 QVEHVRAERNLLAEVDSNCIVKLYCSFQDNEYLYLIMEYLPGGDMMTLLMRKDTLSEDEA 237
Query: 448 RFYMAECILAIEVIHKLGFIHRDIKPDNILIDIRGHIKLSDFGLSTGFHKTHDSSYYXXX 507
+FY+AE +LAIE IH +IHRDIKPDN+L+D GH++LSDFGL K D S
Sbjct: 238 KFYIAESVLAIESIHNRNYIHRDIKPDNLLLDRYGHLRLSDFGLC----KPLDCSVIDGE 293
Query: 508 XXXXXXXXXXXXXXXXXXXXXXXXXXPNETNNGNRNTMLVDAIHLTMTNRQQMQTWRKSR 567
N + G ++ + ++Q++ W+K+R
Sbjct: 294 DFTVG----------------------NAGSGGGSESVSTTP---KRSQQEQLEHWQKNR 328
Query: 568 RLMAYSTVGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIM 627
R++AYSTVGTPDYIAPE+ L +GYG ECDWWSLGAIMYE L+G+PPF ++ P T RKI+
Sbjct: 329 RMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGAIMYEMLVGYPPFYADDPMSTCRKIV 388
Query: 628 NFEQTLQFPDDIHISYEAEDLIRRLLTHSENRLGRHGGADEIKAHPFFSGVDWNTIRQVE 687
N++ L+FP++ +S A DLI +LL RLG GA +IKAHP+F GV W I Q+E
Sbjct: 389 NWKTHLKFPEESRLSRGARDLIGKLLCSVNQRLG-STGASQIKAHPWFEGVQWEKIYQME 447
Query: 688 APYIPKLSSVTDTRFFPT-DELENVPDSPXXXXXXXXXXXXXXXXXGVPQSNAKEDLPFI 746
A +IP+++ DT+ F DE +N +P + + +D+ F+
Sbjct: 448 AAFIPEVNDDLDTQNFEKFDEEDNQTQAPSRTGPWR-------------KMLSSKDINFV 494
Query: 747 GYTYSRFD 754
GYTY F+
Sbjct: 495 GYTYKNFE 502
>At4g33080 [R] KOG0605 NDR and related serine/threonine kinases
Length = 483
Score = 379 bits (973), Expect = e-105
Identities = 207/481 (43%), Positives = 285/481 (59%), Gaps = 31/481 (6%)
Query: 274 TQDKAAAVKLKIENFYQSSVGYAIERNQRRLELESELASQDWSEERKNRQLASLGKKESQ 333
T +K AA K IEN Y++ ER +RR LE +LAS +E + + L +KE++
Sbjct: 21 TMEKVAAAKQYIENHYKAQNKNIQERKERRWILERKLASSGVPKEEQINMIKDLERKETE 80
Query: 334 FXXXXXXXXXXDDFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVK 393
F DDF + +IG+GAFGEVRL +++ +G IYAMK L KSEM + Q+ HV+
Sbjct: 81 FMRLKRNKISVDDFELLTIIGRGAFGEVRLCRERKSGNIYAMKKLKKSEMVMRGQVEHVR 140
Query: 394 AERDVLAGSDSPWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAE 453
AER++LA +S ++V LYYSFQD +YLYLIME+LPGGD+MT+L+R EDV RFY+A+
Sbjct: 141 AERNLLAEVESHYIVKLYYSFQDPEYLYLIMEYLPGGDMMTLLMREDTLREDVARFYIAQ 200
Query: 454 CILAIEVIHKLGFIHRDIKPDNILIDIRGHIKLSDFGLSTGFHKTHDSSYYXXXXXXXXX 513
+LAIE IH+ +IHRDIKPDN+L+D GH+KLSDFGL + S
Sbjct: 201 SVLAIESIHRYNYIHRDIKPDNLLLDKDGHMKLSDFGLCKPLDCRNLPSIQENRATDDET 260
Query: 514 XXXXXXXXXXXXXXXXXXXXPNETNNGNRNTMLVDAIHLTMTNRQQMQTWRKSRRLMAYS 573
+E + +R D + ++Q+Q W+ +RR +A+S
Sbjct: 261 M--------------------SEPMDVDRCFPDTDNKRSWRSPQEQLQHWQMNRRKLAFS 300
Query: 574 TVGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTL 633
TVGTPDYIAPE+ L +GYG ECDWWSLGAIMYE L+G+PPF ++ P T RKI+++ L
Sbjct: 301 TVGTPDYIAPEVLLKKGYGMECDWWSLGAIMYEMLVGYPPFYADDPISTCRKIVHWRNHL 360
Query: 634 QFPDDIHISYEAEDLIRRLLTHSENRLGRHGGADEIKAHPFFSGVDWNTIRQVEAPYIPK 693
+FP+D S EA+DLI RLL + ++RLG GGA +IK HP+F V W + ++EA Y P+
Sbjct: 361 KFPEDAKFSSEAKDLICRLLCNVDHRLGTGGGAQQIKDHPWFKDVVWEKLYEMEAAYKPE 420
Query: 694 LSSVTDTRFFPTDELENVPDSPXXXXXXXXXXXXXXXXXGVPQSNAKEDLPFIGYTYSRF 753
++ DT+ F + N P A +DL F+GYTY F
Sbjct: 421 VNDELDTQNFMKFDEVNSPAPERTRSGLSRKMLL-----------APKDLSFVGYTYKNF 469
Query: 754 D 754
D
Sbjct: 470 D 470
>At2g19400 [R] KOG0605 NDR and related serine/threonine kinases
Length = 545
Score = 375 bits (962), Expect = e-103
Identities = 202/443 (45%), Positives = 282/443 (63%), Gaps = 22/443 (4%)
Query: 269 LLTKTTQDKAAAVKLKIENFYQSSVGYAIERNQRRLELESELASQDWSEERKNRQLASLG 328
L++ +T +K AA K IEN Y + + +R +RR LE ++AS D SE+ + L L
Sbjct: 27 LVSNSTLEKVAAAKKYIENHYNRRMRHIQQRKERRWVLEQKIASLDVSEKEQLELLEDLQ 86
Query: 329 KKESQFXXXXXXXXXXDDFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQ 388
+KE+++ DDF+ + +IG+GAFGEVRL ++K TG IYAMK L KSEM ++ Q
Sbjct: 87 RKETEYTRLMRNRLCVDDFDLLSIIGRGAFGEVRLCREKKTGNIYAMKKLKKSEMLSRGQ 146
Query: 389 LAHVKAERDVLAGSDSPWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTR 448
+ HV+AER++LA S +V LYYSFQD +YLYLIME+L GGD+MT+L+R + TE V R
Sbjct: 147 VEHVRAERNLLAEVASDCIVKLYYSFQDPEYLYLIMEYLSGGDVMTLLMREETLTETVAR 206
Query: 449 FYMAECILAIEVIHKLGFIHRDIKPDNILIDIRGHIKLSDFGLSTGFHKTHDSSYYXXXX 508
FY+A+ +LAIE IHK ++HRDIKPDN+L+D GH+KLSDFGL + S+
Sbjct: 207 FYIAQSVLAIESIHKHNYVHRDIKPDNLLLDKYGHMKLSDFGLCKPLDCRNISAMNVNEP 266
Query: 509 XXXXXXXXXXXXXXXXXXXXXXXXXPNETNNGNRNTMLVDAIHLTMTNRQQMQTWRKSRR 568
NE+ +G+ N + + +Q+Q W+ +RR
Sbjct: 267 LNDENI--------------------NESIDGDENCSIGRRGRRWKSPLEQLQHWQINRR 306
Query: 569 LMAYSTVGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMN 628
+AYSTVGTPDYIAPE+ L +GYG ECDWWSLGAIMYE L+G+PPF S+ P T RKI++
Sbjct: 307 KLAYSTVGTPDYIAPEVLLKKGYGVECDWWSLGAIMYEMLVGYPPFYSDDPVTTCRKIVS 366
Query: 629 FEQTLQFPDDIHISYEAEDLIRRLLTHSENRLGRHG-GADEIKAHPFFSGVDWNTIRQVE 687
+ L FP+ ++ EA DLI RLL SE+RLG HG GA++IKAH +F V+W + +++
Sbjct: 367 WRTHLVFPEGARLTPEARDLICRLLCDSEHRLGSHGAGAEQIKAHTWFKDVEWEKLYEMD 426
Query: 688 APYIPKLSSVTDTR-FFPTDELE 709
A + P ++ DT+ F DE+E
Sbjct: 427 AAFKPVVNGELDTQNFMKFDEVE 449
>At4g14350 [R] KOG0605 NDR and related serine/threonine kinases
Length = 475
Score = 369 bits (946), Expect = e-101
Identities = 203/451 (45%), Positives = 270/451 (59%), Gaps = 45/451 (9%)
Query: 306 LESELASQDWSEERKNRQLASLGKKESQFXXXXXXXXXXDDFNSVKVIGKGAFGEVRLVQ 365
LE +LA+ + SEE +N L L KE+++ DDF + +IGKGAFGEVR+ +
Sbjct: 2 LEKKLAAAEVSEEEQNNLLKDLEMKETEYMRRQRHKMGADDFEPLTMIGKGAFGEVRICR 61
Query: 366 KKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDSPWVVSLYYSFQDSQYLYLIME 425
+K TG +YAMK L KSEM + Q+ HVKAER++LA DS +V LY SFQD +YLYLIME
Sbjct: 62 EKGTGNVYAMKKLKKSEMLRRGQVEHVKAERNLLAEVDSNCIVKLYCSFQDEEYLYLIME 121
Query: 426 FLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKLGFIHRDIKPDNILIDIRGHIK 485
+LPGGD+MT+L+R TED RFY+ E +LAIE IHK +IHRDIKPDN+L+D GH+K
Sbjct: 122 YLPGGDMMTLLMRKDTLTEDEARFYIGETVLAIESIHKHNYIHRDIKPDNLLLDKDGHMK 181
Query: 486 LSDFGLSTGFHKTHDSSYYXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPNETNNGNRNTM 545
LSDFGL K D S P T
Sbjct: 182 LSDFGLC----KPLDCS---------NLQEKDFTVARNVSGALQSDGRPVATRR------ 222
Query: 546 LVDAIHLTMTNRQQMQTWRKSRRLMAYSTVGTPDYIAPEIFLYQGYGQECDWWSLGAIMY 605
T ++Q+ W+++RR++AYSTVGTPDYIAPE+ L +GYG ECDWWSLGAIMY
Sbjct: 223 ---------TQQEQLLNWQRNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGAIMY 273
Query: 606 ECLIGWPPFCSETPQETYRKIMNFEQTLQFPDDIHISYEAEDLIRRLLTHSENRLGRHGG 665
E L+G+PPF S+ P T RKI+N+ L+FPD++ +S EA+DLI RLL + E RLG G
Sbjct: 274 EMLVGFPPFYSDDPMTTCRKIVNWRNYLKFPDEVRLSPEAKDLICRLLCNVEQRLGTK-G 332
Query: 666 ADEIKAHPFFSGVDWNTIRQVEAPYIPKLSSVTDTRFFPTDEL--ENVPDSPXXXXXXXX 723
ADEIK HP+F G +W + Q++A +IP+++ DT+ F E + VP S
Sbjct: 333 ADEIKGHPWFRGTEWGKLYQMKAAFIPQVNDELDTQNFEKFEETDKQVPKSAKSGPWR-- 390
Query: 724 XXXXXXXXXGVPQSNAKEDLPFIGYTYSRFD 754
+ + +D+ F+GYTY +
Sbjct: 391 ------------KMLSSKDINFVGYTYKNVE 409
>At5g09890 [R] KOG0605 NDR and related serine/threonine kinases
Length = 495
Score = 364 bits (934), Expect = e-100
Identities = 204/494 (41%), Positives = 291/494 (58%), Gaps = 40/494 (8%)
Query: 263 FERRPDLLTKT--TQDKAAAVKLKIENFYQSSVGYAIERNQRRLELESELASQDWSEERK 320
FE D+ + T+ KAAA K IEN Y++ + ER +RR E + ++ E +
Sbjct: 16 FETETDVAVSSPVTRQKAAAAKQFIENHYKNYLQGLHERMERRREFQRKVQEAQLPVEEQ 75
Query: 321 NRQLASLGKKESQFXXXXXXXXXXDDFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLK 380
+ + +L ++E+++ DDF + VIGKGAFGEVRL + + T ++YAMK L K
Sbjct: 76 DEMMRNLARRETEYMRLQRRKIGIDDFELLTVIGKGAFGEVRLCRLRSTSEVYAMKKLKK 135
Query: 381 SEMYNKDQLAHVKAERDVLAGSDSPWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQ 440
+EM ++ Q+ HV++ER++LA DS ++V L+YSFQDS+ LYLIME+LPGGD+MT+L+R
Sbjct: 136 TEMLSRGQVEHVRSERNLLAEVDSRYIVKLFYSFQDSECLYLIMEYLPGGDIMTLLMRED 195
Query: 441 IFTEDVTRFYMAECILAIEVIHKLGFIHRDIKPDNILIDIRGHIKLSDFGLSTGFHKTHD 500
I +EDV RFY+AE ILAI IH+ ++HRDIKPDN+++D GH+KLSDFGL K D
Sbjct: 196 ILSEDVARFYIAESILAIHSIHQHNYVHRDIKPDNLILDKSGHLKLSDFGLC----KPLD 251
Query: 501 SSYYXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPNETNNGNRNTMLVDAIHLTMTNRQQM 560
Y +E +G + D M Q +
Sbjct: 252 DKY-----------------SSLLLEDDEMLSQDSENQSGKSD---ADKAPWQMPKEQLL 291
Query: 561 QTWRKSRRLMAYSTVGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQ 620
Q W+++RR +AYSTVGT DY+APE+ L +GYG ECDWWSLGAI+YE L+G+PPFCS+ P+
Sbjct: 292 Q-WKRNRRALAYSTVGTLDYMAPEVLLKKGYGMECDWWSLGAILYEMLVGYPPFCSDDPR 350
Query: 621 ETYRKIMNFEQTLQFPDDIHISYEAEDLIRRLLTHSENRLGRHGGADEIKAHPFFSGVDW 680
T RKI+N+ L+FP++ IS EA DLI RLL ++RLG G +EIK+HP+F G W
Sbjct: 351 ITCRKIINWRVCLKFPEEPKISDEARDLICRLLCDVDSRLGTR-GVEEIKSHPWFKGTPW 409
Query: 681 NTIRQVEAPYIPKLSSVTDTRFFPTDELENVPDSPXXXXXXXXXXXXXXXXXGVPQSNAK 740
+ + +EA Y P + DT+ F ++ V SP +
Sbjct: 410 DKLYDMEAAYRPIVDGELDTQNF--EKFPEVEGSPSEAPQVGPWR----------KMLTS 457
Query: 741 EDLPFIGYTYSRFD 754
+D FIG+T+ + D
Sbjct: 458 KDTNFIGFTFKKSD 471
>Hs18959200 [D] KOG0608 Warts/lats-like serine threonine kinases
Length = 1088
Score = 362 bits (928), Expect = 2e-99
Identities = 193/430 (44%), Positives = 268/430 (61%), Gaps = 25/430 (5%)
Query: 280 AVKLKIENFYQSSVGYAIERNQRRLELESELASQDWSEERKNRQLASLGKKESQFXXXXX 339
A K +E ++ + ++ RRL+LE E+A E + + L +KES +
Sbjct: 601 AFKFFMEQHVENVIKTYQQKVNRRLQLEQEMAKAGLCEAEQEQMRKILYQKESNYNRLKR 660
Query: 340 XXXXXDDFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVL 399
F +K +G GAFGEV L K DT +YAMKTL K ++ N++Q+ HVKAERD+L
Sbjct: 661 AKMDKSMFVKIKTLGIGAFGEVCLACKVDTHALYAMKTLRKKDVLNRNQVVHVKAERDIL 720
Query: 400 AGSDSPWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIE 459
A +D+ WVV LYYSFQD LY +M+++PGGD+M++LIR ++F E + RFY+AE LAIE
Sbjct: 721 AEADNEWVVKLYYSFQDKDSLYFVMDYIPGGDMMSLLIRMEVFPEHLARFYIAELTLAIE 780
Query: 460 VIHKLGFIHRDIKPDNILIDIRGHIKLSDFGLSTGFHKTHDSSYYXXXXXXXXXXXXXXX 519
+HK+GFIHRDIKPDNILID+ GHIKL+DFGL TGF TH+S YY
Sbjct: 781 SVHKMGFIHRDIKPDNILIDLDGHIKLTDFGLCTGFRWTHNSKYY--------------- 825
Query: 520 XXXXXXXXXXXXXXPNETNNGNRNTMLVDAIHLTMTNRQQMQTWRKSRRLMAYSTVGTPD 579
P++ + N D + T+ R + Q +R +A+S VGTP+
Sbjct: 826 --QKGSHVRQDSMEPSDLWDDVSNCRCGDRLK-TLEQRARKQ----HQRCLAHSLVGTPN 878
Query: 580 YIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQFPDDI 639
YIAPE+ L +GY Q CDWWS+G I++E L+G PPF + TP ET K++N+E TL P +
Sbjct: 879 YIAPEVLLRKGYTQLCDWWSVGVILFEMLVGQPPFLAPTPTETQLKVINWENTLHIPAQV 938
Query: 640 HISYEAEDLIRRLLTHSENRLGRHGGADEIKAHPFFSGVDWNT-IRQVEAPYIPKLSSVT 698
+S EA DLI +L +++RLGR+ GAD++KAHPFFS +D+++ IR+ APY+P +S
Sbjct: 939 KLSPEARDLITKLCCSADHRLGRN-GADDLKAHPFFSAIDFSSDIRKQPAPYVPTISHPM 997
Query: 699 DT-RFFPTDE 707
DT F P DE
Sbjct: 998 DTSNFDPVDE 1007
>Hs4758666 [D] KOG0608 Warts/lats-like serine threonine kinases
Length = 1130
Score = 347 bits (890), Expect = 4e-95
Identities = 193/446 (43%), Positives = 268/446 (59%), Gaps = 34/446 (7%)
Query: 280 AVKLKIENFYQSSVGYAIERNQRRLELESELASQDWSEERKNRQLASLGKKESQFXXXXX 339
A K +E ++ + +R R+ +LE+E+ S++ +++ L +KES +
Sbjct: 638 AFKFFMEQHVENVLKSHQQRLHRKKQLENEMMRVGLSQDAQDQMRKMLCQKESNYIRLKR 697
Query: 340 XXXXXDDFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVL 399
F +K +G GAFGEV L +K DT +YA KTL K ++ ++Q+AHVKAERD+L
Sbjct: 698 AKMDKSMFVKIKTLGIGAFGEVCLARKVDTKALYATKTLRKKDVLLRNQVAHVKAERDIL 757
Query: 400 AGSDSPWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIE 459
A +D+ WVV LYYSFQD LY +M+++PGGD+M++LIR IF E + RFY+AE A+E
Sbjct: 758 AEADNEWVVRLYYSFQDKDNLYFVMDYIPGGDMMSLLIRMGIFPESLARFYIAELTCAVE 817
Query: 460 VIHKLGFIHRDIKPDNILIDIRGHIKLSDFGLSTGFHKTHDSSYYXXXXXXXXXXXXXXX 519
+HK+GFIHRDIKPDNILID GHIKL+DFGL TGF THDS YY
Sbjct: 818 SVHKMGFIHRDIKPDNILIDRDGHIKLTDFGLCTGFRWTHDSKYY----------QSGDH 867
Query: 520 XXXXXXXXXXXXXXPNETNNGNRNTMLVDAIHLTMTNRQQMQTWRKSRRLMAYSTVGTPD 579
P+ G+R L + + R+ +R +A+S VGTP+
Sbjct: 868 PRQDSMDFSNEWGDPSSCRCGDRLKPL------------ERRAARQHQRCLAHSLVGTPN 915
Query: 580 YIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQFPDDI 639
YIAPE+ L GY Q CDWWS+G I++E L+G PPF ++TP ET K++N++ +L P
Sbjct: 916 YIAPEVLLRTGYTQLCDWWSVGVILFEMLVGQPPFLAQTPLETQMKVINWQTSLHIPPQA 975
Query: 640 HISYEAEDLIRRLLTHSENRLGRHGGADEIKAHPFFSGVDWNT-IRQVEAPYIPKLSSVT 698
+S EA DLI +L E+RLG++ GADEIKAHPFF +D+++ +RQ A YIPK++ T
Sbjct: 976 KLSPEASDLIIKLCRGPEDRLGKN-GADEIKAHPFFKTIDFSSDLRQQSASYIPKITHPT 1034
Query: 699 DT-RFFPTD---------ELENVPDS 714
DT F P D E ENV D+
Sbjct: 1035 DTSNFDPVDPDKLWSDDNEEENVNDT 1060
>7301980 [D] KOG0608 Warts/lats-like serine threonine kinases
Length = 1105
Score = 343 bits (880), Expect = 6e-94
Identities = 186/429 (43%), Positives = 261/429 (60%), Gaps = 30/429 (6%)
Query: 280 AVKLKIENFYQSSVGYAIERNQRRLELESELASQDWSEERKNRQLASLGKKESQFXXXXX 339
A K +E ++ + +R R+ +LE E+ ++ + L +KES +
Sbjct: 652 AFKFFMEQHIENVIKSYRQRTYRKNQLEKEMHKVGLPDQTQIEMRKMLNQKESNYIRLKR 711
Query: 340 XXXXXDDFNSVKVIGKGAFGEVRLVQKKDTGK-IYAMKTLLKSEMYNKDQLAHVKAERDV 398
F +K IG GAFGEV LV K DT +YAMKTL K+++ ++Q+AHVKAERD+
Sbjct: 712 AKMDKSMFVKLKPIGVGAFGEVTLVSKIDTSNHLYAMKTLRKADVLKRNQVAHVKAERDI 771
Query: 399 LAGSDSPWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAI 458
LA +D+ WVV LYYSFQD LY +M+++PGGDLM++LI+ IF E++ RFY+AE A+
Sbjct: 772 LAEADNNWVVKLYYSFQDKDNLYFVMDYIPGGDLMSLLIKLGIFEEELARFYIAEVTCAV 831
Query: 459 EVIHKLGFIHRDIKPDNILIDIRGHIKLSDFGLSTGFHKTHDSSYYXXXXXXXXXXXXXX 518
+ +HK+GFIHRDIKPDNILID GHIKL+DFGL TGF TH+S YY
Sbjct: 832 DSVHKMGFIHRDIKPDNILIDRDGHIKLTDFGLCTGFRWTHNSKYY-------------- 877
Query: 519 XXXXXXXXXXXXXXXPNETNNGNRNTMLVDAIHLTMTNRQQMQTWRKSRRLMAYSTVGTP 578
+ NG + T+L R++M R +R++A+S VGTP
Sbjct: 878 QENGNHSRQDSMEPWEEYSENGPKPTVL---------ERRRM---RDHQRVLAHSLVGTP 925
Query: 579 DYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQFPDD 638
+YIAPE+ GY Q CD+WS+G I+YE L+G PPF + +P ET +K++N+E+TL P
Sbjct: 926 NYIAPEVLERSGYTQLCDYWSVGVILYEMLVGQPPFLANSPLETQQKVINWEKTLHIPPQ 985
Query: 639 IHISYEAEDLIRRLLTHSENRLGRHGGADEIKAHPFFSGVDWNTIRQVEAPYIPKLSSVT 698
+S EA DLIRRL ++ RLG+ DE+K+H FF G+D+ +R+ +APYIP++ T
Sbjct: 986 AELSREATDLIRRLCASADKRLGK--SVDEVKSHDFFKGIDFADMRKQKAPYIPEIKHPT 1043
Query: 699 DT-RFFPTD 706
DT F P D
Sbjct: 1044 DTSNFDPVD 1052
>CE13844 [D] KOG0608 Warts/lats-like serine threonine kinases
Length = 908
Score = 318 bits (816), Expect = 1e-86
Identities = 172/425 (40%), Positives = 246/425 (57%), Gaps = 35/425 (8%)
Query: 298 ERNQRRLELESELASQDWSEERKNRQLASLGKKESQFXXXXXXXXXXDDFNSVKVIGKGA 357
ER +R +LE E+ S + +N+ L L +KES++ F + IG GA
Sbjct: 453 EREKRMKQLEKEMVSAQLPDIMRNKMLGLLQQKESKYTRLRRQKMSKSHFTVISHIGVGA 512
Query: 358 FGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDSPWVVSLYYSFQDS 417
FG+V LV+K DT K+YAMK+L K+++ K Q AHVKAERD+LA +DSPW+V L++SFQD
Sbjct: 513 FGKVSLVRKNDTRKVYAMKSLEKADVIMKQQAAHVKAERDILAEADSPWIVRLFFSFQDD 572
Query: 418 QYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKLGFIHRDIKPDNIL 477
LY IME++PGGD+MT+LI+ IF ED+ RFY+AE AIE +H +GFIHRD+KPDNIL
Sbjct: 573 ACLYFIMEYVPGGDMMTLLIQKGIFEEDLARFYIAELACAIEYVHNVGFIHRDLKPDNIL 632
Query: 478 IDIRGHIKLSDFGLSTGFHKTHDSSYYXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPNET 537
ID GHIKL+DFGL TG THD YY P
Sbjct: 633 IDQHGHIKLTDFGLCTGLRWTHDRRYY----------------------------GPEND 664
Query: 538 NNGNRNTMLVDAIHLTMTNRQQMQTWRKSRRLMAYSTVGTPDYIAPEIFLYQGYGQECDW 597
++ + L + + + + +++RR+ A+S VGT +Y+APE+ G+ Q CDW
Sbjct: 665 HHRVDSFSLPPEVAAIDKSVKVLNVRQQTRRITAHSLVGTGNYMAPEVIAKTGHNQSCDW 724
Query: 598 WSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQFPDDIHISYEAEDLIRRLLTHSE 657
WS G I+YE + G PF +TP T +I N+ L F ++S E +I++L+ +
Sbjct: 725 WSTGVILYEMVFGRVPFHDDTPGGTQHRIKNWRNFLDFTYCGNLSKECLMMIQQLICDAS 784
Query: 658 NRLGRHG-----GADEIKAHPFFSGVDWNTIRQVEAP--YIPKLSSVTDTRFFPTDELEN 710
+RLG HG ++K HP+F G+DW +R++ A YIP+++ DT F T + +
Sbjct: 785 SRLGSHGKDVAERTAQVKNHPWFRGIDWVNLRKLRADYIYIPRVTHDEDTSNFETFQDND 844
Query: 711 VPDSP 715
D P
Sbjct: 845 RADKP 849
>At5g62310 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 1168
Score = 244 bits (623), Expect = 4e-64
Identities = 143/374 (38%), Positives = 215/374 (57%), Gaps = 50/374 (13%)
Query: 345 DDFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDS 404
+DF +K I +GAFG V L +K+ TG ++A+K L K++M K+ + + AER++L +
Sbjct: 752 EDFEIIKPISRGAFGRVFLAKKRATGDLFAIKVLKKADMIRKNAVESILAERNILISVRN 811
Query: 405 PWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKL 464
P+VV +YSF + LYL+ME+L GGDL ++L ED+ R Y+AE +LA+E +H +
Sbjct: 812 PFVVRFFYSFTCRENLYLVMEYLNGGDLFSLLRNLGCLDEDMARIYIAEVVLALEYLHSV 871
Query: 465 GFIHRDIKPDNILIDIRGHIKLSDFGLSTG--FHKTHDSSYYXXXXXXXXXXXXXXXXXX 522
IHRD+KPDN+LI+ GHIKL+DFGLS + T D S
Sbjct: 872 NIIHRDLKPDNLLINQDGHIKLTDFGLSKVGLINSTDDLS-------------------- 911
Query: 523 XXXXXXXXXXXPNETNNGNRNTMLVDAIHLTMTNRQQMQTWRKSRRLMAYSTVGTPDYIA 582
E++ GN D ++ Q + SR+ ++ VGTPDY+A
Sbjct: 912 ------------GESSLGNSGFFAEDG------SKAQHSQGKDSRK--KHAVVGTPDYLA 951
Query: 583 PEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQFPD-DIHI 641
PEI L G+G+ DWWS+G I++E L+G PPF +ETPQ+ + I+N + + +P+ I
Sbjct: 952 PEILLGMGHGKTADWWSVGVILFEVLVGIPPFNAETPQQIFENIIN--RDIPWPNVPEEI 1009
Query: 642 SYEAEDLIRRLLTHSENRLGRHG--GADEIKAHPFFSGVDWNTIRQVEAPYIPKLSSVTD 699
SYEA DLI +LLT EN + R G GA E+K H FF ++W+T+ + +A ++P + D
Sbjct: 1010 SYEAHDLINKLLT--ENPVQRLGATGAGEVKQHHFFKDINWDTLARQKAMFVPS-AEPQD 1066
Query: 700 TRFFPTDELENVPD 713
T +F + + N D
Sbjct: 1067 TSYFMSRYIWNPED 1080
>SPCC417.06c [R] KOG0605 NDR and related serine/threonine kinases
Length = 624
Score = 243 bits (621), Expect = 6e-64
Identities = 157/500 (31%), Positives = 246/500 (48%), Gaps = 75/500 (15%)
Query: 274 TQDKAAAVKLKIENFYQSSVGYAIERNQRRLELESELASQDWSEERK------NRQLASL 327
T+ K A ++ N+Y S++ Y R +R E + +S S++++ R+ A L
Sbjct: 91 TRRKRMACQVFFLNYYISTIEYHKLRKERLEEFTACTSSLKQSKQKRLWKEHCGRERAFL 150
Query: 328 GKKESQFXXXXXXXXXXDDFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKD 387
KK ++ F+ + +G+G +G V L +K++T ++ AMK + KS + +
Sbjct: 151 RKKRTKIQCSH--------FDLLVKLGQGGYGSVWLAKKRNTHELLAMKMMKKSTLQQLN 202
Query: 388 QLAHVKAERDVLAGSDSPWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVT 447
++ H+ ERD+L ++S W+V LYY+FQD + +YL ME++PGGD T L + E+ T
Sbjct: 203 EVKHILNERDILTNTNSEWLVKLYYAFQDKEKVYLAMEYVPGGDFRTFLTTKGLLHENQT 262
Query: 448 RFYMAECILAIEVIHKLGFIHRDIKPDNILIDIRGHIKLSDFGLSTGFHKTHDSSYYXXX 507
RFY+AE + AI +HKLG++HRD+KP+N LID +GHIKLSDFGLST
Sbjct: 263 RFYLAEMVAAISAVHKLGYMHRDLKPENFLIDQKGHIKLSDFGLSTAI------------ 310
Query: 508 XXXXXXXXXXXXXXXXXXXXXXXXXXPNETNNGNRNTMLVDAI-----HLTMTNRQQM-Q 561
N+ N LV A+ +LT R+ + +
Sbjct: 311 ------------------------VTSNQVN--RLQHALVSAVNPQRPYLTQKQRRNIYK 344
Query: 562 TWRKSRRLMAYSTVGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQE 621
+ S VG+P+Y+APE+ + Y + D+WSLG I YECL+G+PPF T QE
Sbjct: 345 ALLEKNENKVNSVVGSPEYMAPEVVYGKKYDRTVDYWSLGCICYECLVGYPPFSGSTLQE 404
Query: 622 TYRKIMNFEQTLQFPDDIH----------ISYEAEDLIRRLLTHSENRLGRHGGADEIKA 671
T+ + + + LQ P +S EA I + LT +R EI+
Sbjct: 405 TWTNLYYWREMLQRPSKNENGIYDKKARSVSDEAWSFITKCLTEPTSRF---QSTIEIQK 461
Query: 672 HPFFSGVDWNTIR-QVEAPYIPKLSSVTDTRFFPTDELENVPDSPXXXXXXXXXXXXXXX 730
HPFF + WN +R + P++P+L + DT +F E V D+
Sbjct: 462 HPFFKRLHWNGLRKRAVPPFVPRLENQLDTSYFDDFNDEQVLDAYKDVYEKQRKAEQKAK 521
Query: 731 XXGVPQSNAKEDLPFIGYTY 750
GV N ++ F+G+T+
Sbjct: 522 SNGVMNGNQRQ---FLGFTF 538
>SPAC24B11.11c [R] KOG0605 NDR and related serine/threonine kinases
Length = 607
Score = 241 bits (614), Expect = 4e-63
Identities = 149/505 (29%), Positives = 234/505 (45%), Gaps = 52/505 (10%)
Query: 254 NGSANNYMYFERRPDLLTKTTQDKAAAVKLKIENFYQSSVGYAIERNQRRLELESELASQ 313
NGS N + E ++ + A ++ + Y + Y R QR E +L +
Sbjct: 119 NGSMN--LSVEEMEKVVQPKVKRMATICQMFFLDHYFEQLHYLYTRKQRARLFEEQLLKE 176
Query: 314 DWSEERKNRQLASLGKKESQFXXXXXXXXXXDDFNSVKVIGKGAFGEVRLVQKKDTGKIY 373
+ R++ + +E + DF ++ +G+G +G V L +K+DT +I
Sbjct: 177 P--DSRRDELVKRYNGRERVYLRKRRTRISHGDFQTITQVGQGGYGSVWLARKRDTKEIV 234
Query: 374 AMKTLLKSEMYNKDQLAHVKAERDVLAGSDSPWVVSLYYSFQDSQYLYLIMEFLPGGDLM 433
A+K + KS ++ D++ HV ERD+L ++S W+V L Y+FQD+ +YL MEF+PGGD
Sbjct: 235 ALKIMNKSVLHKMDEIRHVLTERDILTTANSEWLVRLLYAFQDTSNIYLAMEFVPGGDFR 294
Query: 434 TMLIRWQIFTEDVTRFYMAECILAIEVIHKLGFIHRDIKPDNILIDIRGHIKLSDFGLST 493
T+L + + +FY E LAI+ +H+LG+IHRD+KP+N L+ GHIKL+DFGLS+
Sbjct: 295 TLLSNSGVLRDHHAKFYATEMFLAIDALHQLGYIHRDLKPENFLVGASGHIKLTDFGLSS 354
Query: 494 GFHKTHDSSYYXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPNETNNGNRNTMLVDAIHLT 553
G E NN +V
Sbjct: 355 GI--------------------------ISKKKIESMKIRLQEVNN------VVVPERSM 382
Query: 554 MTNRQQMQTWRKSRRLMAYSTVGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPP 613
RQ +T + A+S VG+PDY+APE+ + Y D+WSLG IMYECL G+PP
Sbjct: 383 RERRQVFRTLLSQDPVYAHSVVGSPDYMAPEVLRGENYNHSVDYWSLGCIMYECLSGFPP 442
Query: 614 FCSETPQETYRKIMNFEQTLQFPD-----DIHISY--EAEDLIRRLLTHSENRLGRHGGA 666
F ET+ + N+ + Q P D+ ++ +A D + +T ++R
Sbjct: 443 FSGSNVNETWSNLKNWRKCFQRPHYDDPRDLEFNWRDDAWDFVCHCITDPKDRF---CSL 499
Query: 667 DEIKAHPFFSGVDWNTIRQV-EAPYIPKLSSVTDTRFFPTDELENVPDSPXXXXXXXXXX 725
++ HP+FS +DW +R P++P L+S D +F EN
Sbjct: 500 KQVMQHPYFSKIDWKNVRTAYRPPFVPDLNSEIDAGYFDDFTNENDMSKYKEVHEKQAAI 559
Query: 726 XXXXXXXGVPQSNAKEDLPFIGYTY 750
P+ NA FIG+T+
Sbjct: 560 ANMVNTFNKPKRNA-----FIGFTF 579
>At1g48490 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 1244
Score = 241 bits (614), Expect = 4e-63
Identities = 139/361 (38%), Positives = 199/361 (54%), Gaps = 49/361 (13%)
Query: 345 DDFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDS 404
DDF +K I +GAFG V L +K TG ++A+K L K++M K+ + + AERD+L + +
Sbjct: 826 DDFEVMKSISRGAFGHVILARKNTTGDLFAIKVLRKADMIRKNAVESILAERDILINARN 885
Query: 405 PWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKL 464
P+VV +YSF S+ LYL+ME+L GGD +ML + E R Y+AE +LA+E +H
Sbjct: 886 PFVVRFFYSFTCSENLYLVMEYLNGGDFYSMLRKIGCLDEANARVYIAEVVLALEYLHSE 945
Query: 465 GFIHRDIKPDNILIDIRGHIKLSDFGLSTGFHKTHDSSYYXXXXXXXXXXXXXXXXXXXX 524
G +HRD+KPDN+LI GH+KL+DFGLS
Sbjct: 946 GVVHRDLKPDNLLIAHDGHVKLTDFGLS-------------------------------- 973
Query: 525 XXXXXXXXXPNETNNGNRNTMLVDAIHLTMTNRQQMQTWRKSRRLMAYSTVGTPDYIAPE 584
N + + + A L + + ++ T R S VGTPDY+APE
Sbjct: 974 -------KVGLINNTDDLSGPVSSATSLLVEEKPKLPTLDHKR-----SAVGTPDYLAPE 1021
Query: 585 IFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQFPD-DIHISY 643
I L G+G DWWS+G I+YE L+G PPF ++ PQ+ + I+N + +Q+P +S+
Sbjct: 1022 ILLGTGHGATADWWSVGIILYEFLVGIPPFNADHPQQIFDNILN--RNIQWPPVPEDMSH 1079
Query: 644 EAEDLIRRLLTHS-ENRLGRHGGADEIKAHPFFSGVDWNTIRQVEAPYIPKLSSVTDTRF 702
EA DLI RLLT RLG G A E+K H FF +DWNT+ Q +A ++P + DT +
Sbjct: 1080 EARDLIDRLLTEDPHQRLGARGAA-EVKQHSFFKDIDWNTLAQQKAAFVPDSENAFDTSY 1138
Query: 703 F 703
F
Sbjct: 1139 F 1139
>At3g17850 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 1263
Score = 237 bits (604), Expect = 6e-62
Identities = 139/372 (37%), Positives = 201/372 (53%), Gaps = 45/372 (12%)
Query: 345 DDFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDS 404
DDF +K I +GAFG V L +K+ TG ++A+K L K++M K+ + + AERD+L +
Sbjct: 888 DDFEIIKPISRGAFGRVFLAKKRTTGDLFAIKVLKKADMIRKNAVESILAERDILINVRN 947
Query: 405 PWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKL 464
P+VV +YSF LYL+ME+L GGDL ++L ED+ R Y+AE +LA+E +H
Sbjct: 948 PFVVRFFYSFTCRDNLYLVMEYLNGGDLYSLLRNLGCLEEDIVRVYIAEVVLALEYLHSE 1007
Query: 465 GFIHRDIKPDNILIDIRGHIKLSDFGLS-TGFHKTHDSSYYXXXXXXXXXXXXXXXXXXX 523
G +HRD+KPDN+LI GHIKL+DFGLS G + D
Sbjct: 1008 GVVHRDLKPDNLLIAHDGHIKLTDFGLSKVGLINSTD----------------------- 1044
Query: 524 XXXXXXXXXXPNETNNGNRNTMLVDAIHLTMTNRQQMQTWRKSRRLMAYSTVGTPDYIAP 583
+ T L+D + ++ RK R S VGTPDY+AP
Sbjct: 1045 -----------DLAGPAVSGTSLLDEEESRLAASEEQLERRKKR-----SAVGTPDYLAP 1088
Query: 584 EIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQFPD-DIHIS 642
EI L G+G DWWS+G I++E ++G PPF +E PQ+ + I+N + + +P +S
Sbjct: 1089 EILLGTGHGATADWWSVGIILFELIVGIPPFNAEHPQQIFDNILN--RKIPWPHVPEEMS 1146
Query: 643 YEAEDLIRRLLTHS-ENRLGRHGGADEIKAHPFFSGVDWNTIRQVEAPYIPKLSSVTDTR 701
EA D+I R LT RLG G A E+K H FF ++W+T+ + +A ++P S DT
Sbjct: 1147 AEAHDIIDRFLTEDPHQRLGARGAA-EVKQHIFFKDINWDTLARQKAAFVPASESAIDTS 1205
Query: 702 FFPTDELENVPD 713
+F + N D
Sbjct: 1206 YFRSRYSWNTSD 1217
>At1g45160 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 1067
Score = 231 bits (589), Expect = 3e-60
Identities = 137/366 (37%), Positives = 200/366 (54%), Gaps = 57/366 (15%)
Query: 345 DDFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDS 404
DDF +K I +GAFG+V L +K+ TG +A+K L K +M K+ + + ER++L
Sbjct: 668 DDFEIIKPISRGAFGKVFLARKRTTGDFFAIKVLKKLDMIRKNDIERILQERNILITVRY 727
Query: 405 PWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKL 464
P++V +YSF LYL+ME+L GGDL ++L + E++ R Y+AE +LA+E +H L
Sbjct: 728 PFLVRFFYSFTCRDNLYLVMEYLNGGDLYSLLQKVGCLDEEIARIYIAELVLALEYLHSL 787
Query: 465 GFIHRDIKPDNILIDIRGHIK-----LSDFGLSTGFHKTHDSSYYXXXXXXXXXXXXXXX 519
+HRD+KPDN+LI GHIK LS GL + T D S +
Sbjct: 788 KIVHRDLKPDNLLIAYNGHIKLTDFGLSKIGL---INNTIDLSGH--------------- 829
Query: 520 XXXXXXXXXXXXXXPNETNNGNRNTMLVDAIHLTMTNRQQMQTWRKSRRLMAYSTVGTPD 579
E++ R TN Q ++ R+ +S VGTPD
Sbjct: 830 ----------------ESDVSPR------------TNSHHFQKNQEEERIR-HSAVGTPD 860
Query: 580 YIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQFPD-D 638
Y+APEI L +G DWWS G +++E L G PPF + P++ + I+N + + +PD
Sbjct: 861 YLAPEILLGTEHGYAADWWSAGIVLFELLTGIPPFTASRPEKIFDNILNGK--MPWPDVP 918
Query: 639 IHISYEAEDLIRRLLTHS-ENRLGRHGGADEIKAHPFFSGVDWNTIRQVEAPYIPKLSSV 697
+SYEA+DLI RLL H E RLG +G A E+K+HPFF GVDW + +A ++P+ S+
Sbjct: 919 GEMSYEAQDLINRLLVHEPEKRLGANGAA-EVKSHPFFQGVDWENLALQKAAFVPQPESI 977
Query: 698 TDTRFF 703
DT +F
Sbjct: 978 NDTSYF 983
>CE20493 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 1370
Score = 223 bits (569), Expect = 7e-58
Identities = 126/363 (34%), Positives = 200/363 (54%), Gaps = 57/363 (15%)
Query: 345 DDFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDS 404
DDF++++++ GA+G V LV+ ++T + +A+K + K + ++Q+ V AERD+L +D+
Sbjct: 356 DDFDTIRLVSNGAYGAVYLVRHRETRQRFALKKMNKQTLMLRNQVDQVFAERDILTMADN 415
Query: 405 PWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKL 464
P+VVS Y SF+ QYL ++ME++ GGD +L ++ R Y+AE ILAIE +H
Sbjct: 416 PFVVSFYGSFETRQYLCMLMEYVEGGDCAALLKSAGTLPVELVRLYVAETILAIEYLHSY 475
Query: 465 GFIHRDIKPDNILIDIRGHIKLSDFGLSTGFHKTHDSSYYXXXXXXXXXXXXXXXXXXXX 524
G +HRD+KPDN+LI GHIKL+DFGLS
Sbjct: 476 GIVHRDLKPDNLLITAMGHIKLTDFGLS-------------------------------- 503
Query: 525 XXXXXXXXXPNETNNGNRNTMLVDAIHLTMTNRQQMQTWRKSRRLMAYSTVGTPDYIAPE 584
+ NR T++ + + +Q GTP+YIAPE
Sbjct: 504 -----------KIGLMNRTTLVAEGYDAVVETQQ----------FQDKQLCGTPEYIAPE 542
Query: 585 IFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQFP-DDIHISY 643
+ L +GYG+ DWW+LG I+YE L+G PF ETP+ + K+++ + +++P +D +
Sbjct: 543 VILRRGYGKPVDWWALGIILYEFLVGIVPFFGETPEALFSKVIS--EDVEYPEEDEALPP 600
Query: 644 EAEDLIRRLL-THSENRLGRHGGADEIKAHPFFSGVDWNTIRQVEAPYIPKLSSVTDTRF 702
EA DL RRLL + RLG GA ++ AH FF +D+ ++ + +A ++P+L + DT +
Sbjct: 601 EAADLCRRLLEKNPAERLGTLNGAAQLMAHEFFILLDFTSLLRQKAEFVPQLDNEEDTSY 660
Query: 703 FPT 705
F T
Sbjct: 661 FDT 663
>YGR092w [R] KOG0605 NDR and related serine/threonine kinases
Length = 572
Score = 222 bits (565), Expect = 2e-57
Identities = 138/441 (31%), Positives = 217/441 (48%), Gaps = 46/441 (10%)
Query: 274 TQDKAAAVKLKIENFYQSSVGYAIERNQRR------LELESELASQDWSEERKNRQLASL 327
TQ + K+ Y Y I R QR L+ +S+L + D + + N + +S
Sbjct: 100 TQRVVSVCKMYFLEHYCDMFDYVISRRQRTKQVLEYLQQQSQLPNSD--QIKLNEEWSSY 157
Query: 328 GKKESQFXXXXXXXXXXDDFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKD 387
++E Q DF + +G+G +G+V L +KKDT ++ A+K L K ++ +
Sbjct: 158 LQREHQVLRKRRLKPKNRDFEMITQVGQGGYGQVYLARKKDTKEVCALKILNKKLLFKLN 217
Query: 388 QLAHVKAERDVLAGSDSPWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVT 447
+ HV ERD+L + S W+V L Y+FQD Q LYL MEF+PGGD T+LI +
Sbjct: 218 ETKHVLTERDILTTTRSEWLVKLLYAFQDLQSLYLAMEFVPGGDFRTLLINTRCLKSGHA 277
Query: 448 RFYMAECILAIEVIHKLGFIHRDIKPDNILIDIRGHIKLSDFGLSTGFHKTHDSSYYXXX 507
RFY++E A+ +H LG+ HRD+KP+N LID +GHIKL+DFGL+ G
Sbjct: 278 RFYISEMFCAVNALHDLGYTHRDLKPENFLIDAKGHIKLTDFGLAAG------------- 324
Query: 508 XXXXXXXXXXXXXXXXXXXXXXXXXXPNETNNGNRNTMLVDAIHLTMTNRQQMQTWRKSR 567
P T ++ +R++M + +
Sbjct: 325 ----TISNERIESMKIRLEKIKDLEFPAFTEK-------------SIEDRRKMYNQLREK 367
Query: 568 RL-MAYSTVGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKI 626
+ A S VG+PDY+A E+ + Y D+WSLG +++E L+G+ PF + ETY +
Sbjct: 368 EINYANSMVGSPDYMALEVLEGKKYDFTVDYWSLGCMLFESLVGYTPFSGSSTNETYDNL 427
Query: 627 MNFEQTLQFPDD----IHISYEAEDLIRRLLTHSENRLGRHGGADEIKAHPFFSGVDWNT 682
++QTL+ P S DLI RL+ NRL + +K +F+ ++++T
Sbjct: 428 RRWKQTLRRPRQSDGRAAFSDRTWDLITRLIADPINRL---RSFEHVKRMSYFADINFST 484
Query: 683 IRQVEAPYIPKLSSVTDTRFF 703
+R + P+ P+L S TD +F
Sbjct: 485 LRSMIPPFTPQLDSETDAGYF 505
>YPR111w [R] KOG0605 NDR and related serine/threonine kinases
Length = 564
Score = 218 bits (556), Expect = 2e-56
Identities = 138/448 (30%), Positives = 220/448 (48%), Gaps = 42/448 (9%)
Query: 274 TQDKAAAVKLKIENFYQSSVGYAIERNQRRLE----LESELASQDWSEERKNRQLASLGK 329
TQ +L ++Y Y I R QR + LE + + ++ S + N + A +
Sbjct: 92 TQRVVNVCQLYFLDYYCDMFDYVISRRQRTKQVLRYLEQQRSVKNVSNKVLNEEWALYLQ 151
Query: 330 KESQFXXXXXXXXXXDDFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQL 389
+E + DF + +G+G +G+V L +KKD+ +I A+K L K ++ ++
Sbjct: 152 REHEVLRKRRLKPKHKDFQILTQVGQGGYGQVYLAKKKDSDEICALKILNKKLLFKLNET 211
Query: 390 AHVKAERDVLAGSDSPWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRF 449
HV ERD+L + S W+V L Y+FQD + LYL MEF+PGGD T+LI +I RF
Sbjct: 212 NHVLTERDILTTTRSDWLVKLLYAFQDPESLYLAMEFVPGGDFRTLLINTRILKSGHARF 271
Query: 450 YMAECILAIEVIHKLGFIHRDIKPDNILIDIRGHIKLSDFGLSTGFHKTHDSSYYXXXXX 509
Y++E A+ +H+LG+ HRD+KP+N LID GHIKL+DFGL+ G
Sbjct: 272 YISEMFCAVNALHELGYTHRDLKPENFLIDATGHIKLTDFGLAAG--------------- 316
Query: 510 XXXXXXXXXXXXXXXXXXXXXXXXPNETNNGNRNTMLVDAIHLTMTNRQQMQTWRKSRRL 569
E N +I R+ RK+
Sbjct: 317 -----------TVSNERIESMKIRLEEVKNLEFPAFTERSIE---DRRKIYHNMRKTEIN 362
Query: 570 MAYSTVGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNF 629
A S VG+PDY+A E+ + Y D+WSLG +++E L+G+ PF + ETY + +
Sbjct: 363 YANSMVGSPDYMALEVLEGKKYDFTVDYWSLGCMLFESLVGYTPFSGSSTNETYENLRYW 422
Query: 630 EQTLQFP--DDIHISYEAE--DLIRRLLTHSENRLGRHGGADEIKAHPFFSGVDWNTIRQ 685
++TL+ P +D ++ DLI RL+ NR+ ++++ +F+ +++ T+R
Sbjct: 423 KKTLRRPRTEDRRAAFSDRTWDLITRLIADPINRV---RSFEQVRKMSYFAEINFETLRT 479
Query: 686 VEAPYIPKLSSVTDTRFFPTDELENVPD 713
P+IP+L TD +F D+ N D
Sbjct: 480 SSPPFIPQLDDETDAGYF--DDFTNEED 505
>YNR047w [R] KOG0610 Putative serine/threonine protein kinase
Length = 893
Score = 215 bits (548), Expect = 2e-55
Identities = 135/385 (35%), Positives = 200/385 (51%), Gaps = 57/385 (14%)
Query: 314 DWSEERKNRQLASLGKKESQFXXXXXXXXXXDDFNSVKVIGKGAFGEVRLVQKKDTGKIY 373
D+ E R++R+L + +S F ++++G+G G+V LV++K T ++Y
Sbjct: 467 DFPEPRRSRRL----RTKSFSNKFQDIMVGPQSFEKIRLLGQGDVGKVFLVREKKTNRVY 522
Query: 374 AMKTLLKSEMYNKDQLAHVKAERDVLAGSDSPWVVSLYYSFQDSQYLYLIMEFLPGGDLM 433
A+K L K EM ++++ V E+++LA S+ P++V+LY+SFQ YLYL ME+ GG+
Sbjct: 523 ALKVLSKDEMIKRNKIKRVLTEQEILATSNHPFIVTLYHSFQSEDYLYLCMEYCMGGEFF 582
Query: 434 TML--IRWQIFTEDVTRFYMAECILAIEVIHKLGFIHRDIKPDNILIDIRGHIKLSDFGL 491
L + + ED RFY +E A+E +H LGFI+RD+KP+NIL+ GHI LSDF L
Sbjct: 583 RALQTRKTKCICEDDARFYASEVTAALEYLHLLGFIYRDLKPENILLHQSGHIMLSDFDL 642
Query: 492 STGFHKTHDSSYYXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPNETNNGNRNTMLVDAIH 551
S + DS G+ + LVD
Sbjct: 643 SI---QAKDSKV--------------------------------PVVKGSAQSTLVD--- 664
Query: 552 LTMTNRQQMQTWRKSRRLMAYSTVGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGW 611
T S S VGT +YIAPE+ G+ DWW+LG ++YE L G+
Sbjct: 665 ----------TKICSDGFRTNSFVGTEEYIAPEVIRGNGHTAAVDWWTLGILIYEMLFGF 714
Query: 612 PPFCSETPQETYRKIMNFEQTLQFPDDIHISYEAEDLIRRLLTHSEN-RLGRHGGADEIK 670
PF + ET+ I+ E + FP++ IS +DLI++LLT +E+ RLG GA ++K
Sbjct: 715 TPFKGDNTNETFTNILKNE--VSFPNNNEISRTCKDLIKKLLTKNESKRLGCKMGAADVK 772
Query: 671 AHPFFSGVDWNTIRQVEAPYIPKLS 695
HPFF V W+ +R E P IP LS
Sbjct: 773 KHPFFKKVQWSLLRNQEPPLIPVLS 797
>SPAC4G8.05 [R] KOG0610 Putative serine/threonine protein kinase
Length = 566
Score = 207 bits (526), Expect = 6e-53
Identities = 124/357 (34%), Positives = 182/357 (50%), Gaps = 46/357 (12%)
Query: 347 FNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDSPW 406
F V ++GKG G V LV++K +GK YAMK L K EM +++ AE+ +LA S+ P+
Sbjct: 195 FEKVFLLGKGDVGRVYLVREKKSGKFYAMKVLSKQEMIKRNKSKRAFAEQHILATSNHPF 254
Query: 407 VVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIR--WQIFTEDVTRFYMAECILAIEVIHKL 464
+V+LY+SFQ +YLYL ME+ GG+ L R + +E+ +FY+AE A+E +H +
Sbjct: 255 IVTLYHSFQSDEYLYLCMEYCMGGEFFRALQRRPGRCLSENEAKFYIAEVTAALEYLHLM 314
Query: 465 GFIHRDIKPDNILIDIRGHIKLSDFGLSTGFHKTHDSSYYXXXXXXXXXXXXXXXXXXXX 524
GFI+RD+KP+NIL+ GHI LSDF LS
Sbjct: 315 GFIYRDLKPENILLHESGHIMLSDFDLS-------------------------------- 342
Query: 525 XXXXXXXXXPNETNNGNRNTMLVDAIHLTMTNRQQMQTWRKSRRLMAYSTVGTPDYIAPE 584
++N+ T++ + N + T S VGT +YIAPE
Sbjct: 343 ----------KQSNSAGAPTVIQARNAPSAQNAYALDTKSCIADFRTNSFVGTEEYIAPE 392
Query: 585 IFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTL-QFPDDIHISY 643
+ G+ DWW+LG + YE L PF + T+ I++ + ++ D IS
Sbjct: 393 VIKGCGHTSAVDWWTLGILFYEMLYATTPFKGKNRNMTFSNILHKDVIFPEYADAPSISS 452
Query: 644 EAEDLIRRLLTHSEN-RLGRHGGADEIKAHPFFSGVDWNTIRQVEAPYIPKLSSVTD 699
++LIR+LL EN RLG GA ++K HPFF V W +R E P IPKL+ + +
Sbjct: 453 LCKNLIRKLLVKDENDRLGSQAGAADVKLHPFFKNVQWALLRHTEPPIIPKLAPIDE 509
>At3g12690 [R] KOG0610 Putative serine/threonine protein kinase
Length = 577
Score = 194 bits (493), Expect = 4e-49
Identities = 115/353 (32%), Positives = 182/353 (50%), Gaps = 14/353 (3%)
Query: 345 DDFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDS 404
D+F +K +G G G V L + T ++AMK + K+ + ++++L + ER++L+ D
Sbjct: 183 DNFRLLKRLGYGDIGSVYLADLRGTNAVFAMKVMDKASLASRNKLLRAQTEREILSLLDH 242
Query: 405 PWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRW--QIFTEDVTRFYMAECILAIEVIH 462
P++ +LY F+ ++ L+MEF GG+L ++ + + FTE+ RFY +E +LA+E +H
Sbjct: 243 PFLPTLYSYFETDKFYCLVMEFCSGGNLHSLRQKQPSRRFTEEAARFYASEVLLALEYLH 302
Query: 463 KLGFIHRDIKPDNILIDIRGHIKLSDFGLS--TGFHKTHDSSYYXXXXXXXXXXXXXXXX 520
LG ++RD+KP+NIL+ GHI LSDF LS F+ T S
Sbjct: 303 MLGVVYRDLKPENILVRDEGHIMLSDFDLSLRCTFNPTLVKSSSVCSGGGAILNEEFAVN 362
Query: 521 XXXXXXXXXXXXXPNETNNGNRNTMLVDAIHLTMTNRQQMQTWRKSRRLMAYSTVGTPDY 580
P++ ++ + + + + + + + S VGT +Y
Sbjct: 363 GCMHPSAFLPRLLPSKKTRKAKSDSGLGGLSMP-------ELMAEPTDVRSMSFVGTHEY 415
Query: 581 IAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQFPDDIH 640
+APEI +G+G DWW+ G +YE L G PF + + T ++ Q L+FPD H
Sbjct: 416 LAPEIIRGEGHGSAVDWWTFGIFLYELLHGTTPFKGQGNRATLHNVVG--QPLKFPDTPH 473
Query: 641 ISYEAEDLIRRLLTHS-ENRLGRHGGADEIKAHPFFSGVDWNTIRQVEAPYIP 692
+S A DLIR LL R+ GA EIK HPFF GV+W +R P+IP
Sbjct: 474 VSSAARDLIRGLLVKDPHRRIAYTRGATEIKQHPFFEGVNWALVRSAAPPHIP 526
>At1g79250 [R] KOG0610 Putative serine/threonine protein kinase
Length = 517
Score = 194 bits (493), Expect = 4e-49
Identities = 115/357 (32%), Positives = 182/357 (50%), Gaps = 12/357 (3%)
Query: 346 DFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDSP 405
DF +K +G G G V LV+ + T +AMK + K+ + ++++L + ER++L+ D P
Sbjct: 107 DFRLLKRLGYGDIGSVYLVELRGTITYFAMKVMDKASLASRNKLLRAQTEREILSQLDHP 166
Query: 406 WVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRW--QIFTEDVTRFYMAECILAIEVIHK 463
++ +LY F+ ++ L+MEF GG+L ++ + + FTED RF+ +E +LA+E +H
Sbjct: 167 FLPTLYSHFETDKFYCLVMEFCGGGNLYSLRQKQPNKCFTEDAARFFASEVLLALEYLHM 226
Query: 464 LGFIHRDIKPDNILIDIRGHIKLSDFGLSTGFHKT----HDSSYYXXXXXXXXX--XXXX 517
LG ++RD+KP+N+L+ GHI LSDF LS + SS +
Sbjct: 227 LGIVYRDLKPENVLVRDDGHIMLSDFDLSLRCSVSPTLVKSSSVHAAGGGSGSSRPVGLI 286
Query: 518 XXXXXXXXXXXXXXXXPNETNNGNRNTMLVDAIHLTMTNRQQMQTWRKSRRLMAYSTVGT 577
P + +N L N + + + + S VGT
Sbjct: 287 DEDAAVQGCIQPSTFFPRILQSSKKNRKAKSDFGL-FVNGSMPELMAEPTNVKSMSFVGT 345
Query: 578 PDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQFPD 637
+Y+APEI +G+G DWW+ G +YE L G PF + + T ++ Q L+FP+
Sbjct: 346 HEYLAPEIIRGEGHGSAVDWWTFGIFIYELLYGATPFKGQGNRATLHNVIG--QALRFPE 403
Query: 638 DIHISYEAEDLIRRLLT-HSENRLGRHGGADEIKAHPFFSGVDWNTIRQVEAPYIPK 693
H+S A DLI+ LL + R+ GA EIK HPFF GV+W IR P++P+
Sbjct: 404 VPHVSSAARDLIKGLLVKEPQKRIAYKRGATEIKQHPFFEGVNWALIRSATPPHVPE 460
>At5g55910 [R] KOG0610 Putative serine/threonine protein kinase
Length = 498
Score = 189 bits (480), Expect = 1e-47
Identities = 122/370 (32%), Positives = 177/370 (46%), Gaps = 37/370 (10%)
Query: 347 FNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDSPW 406
F +K +G G G V L + T +AMK + K+ + ++ +L + ER++L D P+
Sbjct: 109 FRLLKRLGCGDIGTVHLAELNGTRCYFAMKVMDKTALASRKKLLRAQTEREILQCLDHPF 168
Query: 407 VVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRW--QIFTEDVTRFYMAECILAIEVIHKL 464
+ +LY F+ ++ L+MEF PGGDL T+ R + FTE +FY+AE +LA+E +H L
Sbjct: 169 LPTLYSHFETEKFSCLVMEFCPGGDLHTLRQRQPGKRFTEQAAKFYVAEVLLAMEYLHML 228
Query: 465 GFIHRDIKPDNILIDIRGHIKLSDFGL-----------------STGFHKTHDSSYYXXX 507
G I+RD+KP+N+L+ GH+ LSDF L S G K S
Sbjct: 229 GIIYRDLKPENVLVRDDGHVMLSDFDLSLRCTVSLSIVRSANVGSEGLSKNSVSCSQQPA 288
Query: 508 XXXXXXXXXXXXXXXXXXXXXXXXXXPN---ETNNGNRNTMLVDAIHLTMTNRQQMQTWR 564
+ +T NGN + + T + M
Sbjct: 289 CIQQPSCISMAPTSCFGPRFFSSKSKKDKKPKTENGNHQVTPLPELVAEPTGARSM---- 344
Query: 565 KSRRLMAYSTVGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYR 624
S VGT +Y+APEI +G+G DWW+ G +YE L G PF + T
Sbjct: 345 --------SFVGTHEYLAPEIIKGEGHGSAVDWWTFGIFLYELLFGKTPFKGSGNRATLF 396
Query: 625 KIMNFEQTLQFPDDIHISYEAEDLIRRLLT-HSENRLGRHGGADEIKAHPFFSGVDWNTI 683
++ Q L+FP+ +S+ A DLIR LL ++RL GA EIK HPFF GV+W +
Sbjct: 397 NVVG--QPLRFPESPVVSFAARDLIRSLLVKEPQHRLAYKRGATEIKQHPFFEGVNWALV 454
Query: 684 RQVEAPYIPK 693
R P IPK
Sbjct: 455 RCASPPEIPK 464
>At5g03640 [R] KOG0610 Putative serine/threonine protein kinase
Length = 926
Score = 187 bits (475), Expect = 5e-47
Identities = 118/359 (32%), Positives = 179/359 (48%), Gaps = 17/359 (4%)
Query: 347 FNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDSPW 406
FN +K +G G G V L + T ++A+K + + +++++ + E+D+L D P+
Sbjct: 541 FNLLKKLGCGDIGTVYLAELTGTNCLFAIKVMDNEFLERRNKMSRAQTEKDILKMLDHPF 600
Query: 407 VVSLYYSFQDSQYLYLIMEFLPGGDLMTMLI----RWQIFTEDVTRFYMAECILAIEVIH 462
+ +LY F L+ME PGGDL + RW F E RFY+AE +LA+E +H
Sbjct: 601 LPTLYAHFTSDNLSCLVMECCPGGDLHVLRQKQPGRW--FPEPAARFYVAEVLLALEYLH 658
Query: 463 KLGFIHRDIKPDNILIDIRGHIKLSDFGLSTGFHKT-----HDSSYYXXXXXXXXXXXXX 517
LG I+RD+KP+NIL+ GHI ++DF LS + S +
Sbjct: 659 MLGVIYRDLKPENILVRDDGHIMVTDFDLSLRCTVSPTLLNSSSPLHADAMRLSSGSRTG 718
Query: 518 XXXXXXXXXXXXXXXXPNETNNGNRNTMLVDAIH---LTMTNRQQMQTWRKSRRLMAYST 574
G ++ M++ + L + Q + + S
Sbjct: 719 SNCIEPSCFRPKLSRGSGPKKKGKQHRMMMKKLKKSDLIARFKSLPQLVAEPTDARSNSF 778
Query: 575 VGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQ 634
VGT +Y+APEI +G+G DWW+ G +YE L G PF T +ET ++ Q+L+
Sbjct: 779 VGTHEYLAPEIIKGEGHGAAVDWWTFGIFLYELLYGKTPFKGATNEETIANVV--LQSLK 836
Query: 635 FPDDIHISYEAEDLIRRLLT-HSENRLGRHGGADEIKAHPFFSGVDWNTIRQVEAPYIP 692
FPD+ ++S++A+DLIR LL ENRLG GA EIK H FF G++W IR P +P
Sbjct: 837 FPDNPNVSFQAKDLIRGLLVKEPENRLGTEKGAAEIKRHAFFEGLNWALIRCAIPPELP 895
>At1g16440 [R] KOG0610 Putative serine/threonine protein kinase
Length = 431
Score = 186 bits (472), Expect = 1e-46
Identities = 116/374 (31%), Positives = 190/374 (50%), Gaps = 22/374 (5%)
Query: 346 DFNSVKVIGKGAFGEVRLVQKKDTGKI--YAMKTLLKSEMYNKDQLAHVKAERDVLAGSD 403
DF +K +G G G V LV+ K +AMK + K+ + ++++L + ER++L+ D
Sbjct: 44 DFRVLKRLGYGDIGSVYLVELKGANPTTYFAMKVMDKASLVSRNKLLRAQTEREILSQLD 103
Query: 404 SPWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRW--QIFTEDVTRFYMAECILAIEVI 461
P++ +LY F+ ++ L+MEF GG+L ++ + + FTED RF+ +E +LA+E +
Sbjct: 104 HPFLPTLYSHFETDKFYCLVMEFCSGGNLYSLRQKQPNKCFTEDAARFFASEVLLALEYL 163
Query: 462 HKLGFIHRDIKPDNILIDIRGHIKLSDFGLS--TGFHKTHDSSYYXXXXXXXXXXXXXXX 519
H LG ++RD+KP+N+L+ GHI LSDF LS + T S+
Sbjct: 164 HMLGIVYRDLKPENVLVRDDGHIMLSDFDLSLRCSVNPTLVKSFNGGGTTGIIDDNAAVQ 223
Query: 520 XXXXXXXXXXXXXXPNETNNGNRNTMLVDAIHLTMTNRQQMQTWRKSRRLMAYSTVGTPD 579
++ N +++ + + + + + S VGT +
Sbjct: 224 GCYQPSAFFPRMLQSSKKNRKSKSDF----------DGSLPELMAEPTNVKSMSFVGTHE 273
Query: 580 YIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQFPDDI 639
Y+APEI +G+G DWW+ G +YE L G PF + + T ++ Q L+FP+
Sbjct: 274 YLAPEIIKNEGHGSAVDWWTFGIFIYELLHGATPFKGQGNKATLYNVIG--QPLRFPEYS 331
Query: 640 HISYEAEDLIRRLLT-HSENRLGRHGGADEIKAHPFFSGVDWNTIRQVEAPYIPKLSSVT 698
+S A+DLI+ LL +NR+ GA EIK HPFF GV+W IR P++P+
Sbjct: 332 QVSSTAKDLIKGLLVKEPQNRIAYKRGATEIKQHPFFEGVNWALIRGETPPHLPE---PV 388
Query: 699 DTRFFPTDELENVP 712
D + E E++P
Sbjct: 389 DFSCYVKKEKESLP 402
>At3g52890 [R] KOG0610 Putative serine/threonine protein kinase
Length = 934
Score = 184 bits (466), Expect = 6e-46
Identities = 119/361 (32%), Positives = 175/361 (47%), Gaps = 17/361 (4%)
Query: 347 FNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDSPW 406
FN +K +G G G V L + T ++A+K + + + + +AER++L D P+
Sbjct: 538 FNLLKKLGCGDIGTVYLAELIGTNCLFAIKVMDNEFLARRKKSPRAQAEREILKMLDHPF 597
Query: 407 VVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRW--QIFTEDVTRFYMAECILAIEVIHKL 464
+ +LY F L+ME+ PGGDL + + + F E RFY+AE +LA+E +H L
Sbjct: 598 LPTLYAQFTSDNLSCLVMEYCPGGDLHVLRQKQLGRCFPEPAARFYVAEILLALEYLHML 657
Query: 465 GFIHRDIKPDNILIDIRGHIKLSDFGLSTGF--------HKTHDSSYYXXXXXXXXXXXX 516
G I+RD+KP+NIL+ GHI L+DF LS +
Sbjct: 658 GIIYRDLKPENILVREDGHIMLTDFDLSLRCAVNPTLVRSNSPPGKDPARISGPYNTSNC 717
Query: 517 XXXXXXXXXXXXXXXXXPNETNNGNRNTMLVDAIHLTMT----NRQQMQTWRKSRRLMAY 572
P ++N + HL+ T +R Q + +
Sbjct: 718 IQPFCITEPSCQVSCFSPRLSSNQQQGRKPKRGDHLSKTQQHLSRSLPQLVAEPTEARSN 777
Query: 573 STVGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQT 632
S VGT +Y+APEI +G+G DWW+ G ++YE L G PF ET ++ Q
Sbjct: 778 SFVGTHEYLAPEIIKGEGHGAAVDWWTFGVLLYELLYGKTPFKGYNNDETLANVV--LQN 835
Query: 633 LQFPDDIHISYEAEDLIRRLLT-HSENRLGRHGGADEIKAHPFFSGVDWNTIRQVEAPYI 691
L+FPD +S++A+DLIR LL ENRLG G+ EIK HPFF G++W IR P +
Sbjct: 836 LKFPDSPLVSFQAKDLIRGLLVKEPENRLGSEKGSVEIKRHPFFEGLNWALIRCAIPPEL 895
Query: 692 P 692
P
Sbjct: 896 P 896
>At2g44830 [R] KOG0610 Putative serine/threonine protein kinase
Length = 762
Score = 183 bits (464), Expect = 1e-45
Identities = 119/358 (33%), Positives = 176/358 (48%), Gaps = 16/358 (4%)
Query: 347 FNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDSPW 406
F +K +G G G V L + T +A+K + K+ + ++ +L + ERD+L D P+
Sbjct: 360 FKLLKRLGCGDIGSVYLAELSGTRCHFAVKVMDKASLEDRKKLNRAQTERDILQLLDHPF 419
Query: 407 VVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRW--QIFTEDVTRFYMAECILAIEVIHKL 464
+ +LY F+ ++ L+ME+ PGGDL T+ R + F+E RFY AE +LA+E +H L
Sbjct: 420 LPTLYTHFETDRFSCLVMEYCPGGDLHTLRQRQPGKHFSEYAARFYAAEVLLALEYLHML 479
Query: 465 GFIHRDIKPDNILIDIRGHIKLSDFGL------STGFHKTHDS--SYYXXXXXXXXXXXX 516
G ++RD+KP+N+L+ GHI LSDF L S KT DS S
Sbjct: 480 GVVYRDLKPENVLVRDDGHIMLSDFDLSLRCAVSPTLIKTFDSDPSRRGAFCVQPACMEP 539
Query: 517 XXXXXXXXXXXXXXXXXPNETNNGNRNTMLVDAIHLTMTNRQQMQTWRKSRRLMAYSTVG 576
PN+ D + ++ +R + S VG
Sbjct: 540 TSACIIQPSCFLPRSIFPNKNKKNKSRKTQADFFKSHSGSLPELVAEPNTRSM---SFVG 596
Query: 577 TPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQFP 636
T +Y+APEI +G+G DWW+ G ++E L G PF + T ++ + L+FP
Sbjct: 597 THEYLAPEIIKGEGHGSAVDWWTFGIFVHELLYGKTPFKGSGNRATLFNVVG--EQLKFP 654
Query: 637 DDIHISYEAEDLIRRLLTHS-ENRLGRHGGADEIKAHPFFSGVDWNTIRQVEAPYIPK 693
+ SY DLI+ LL +NRLG GA EIK HPFF GV+W IR P +P+
Sbjct: 655 ESPATSYAGRDLIQALLVKDPKNRLGTKRGATEIKQHPFFEGVNWALIRCSTPPEVPR 712
>At2g36350 [R] KOG0610 Putative serine/threonine protein kinase
Length = 949
Score = 180 bits (456), Expect = 8e-45
Identities = 120/366 (32%), Positives = 176/366 (47%), Gaps = 25/366 (6%)
Query: 347 FNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDSPW 406
FN +K +G G G V L + T ++A+K + + + + +AER +L D P+
Sbjct: 559 FNLLKKLGCGDIGTVYLAELVGTNCLFAIKVMDNEFLARRKKTPRAQAERAILKMLDHPF 618
Query: 407 VVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRW--QIFTEDVTRFYMAECILAIEVIHKL 464
+ +LY F L+ME+ PGGDL + + + F+E TRFY+AE +LA+E +H L
Sbjct: 619 LPTLYAQFTSDNLSCLVMEYCPGGDLHVLRQKQLSRCFSEPATRFYVAEILLALEYLHML 678
Query: 465 GFIHRDIKPDNILIDIRGHIKLS--DFGLSTGFHKT-------------HDSSYYXXXXX 509
G I+RD+KP+NIL+ GHI L+ D L + T S Y
Sbjct: 679 GVIYRDLKPENILVREDGHIMLTDFDLSLRCAVNPTLLRSTSPPEKDPARMSGPYSTSNC 738
Query: 510 XXXXXXXXXXXXXXXXXXXXXXXXPNETNNGNRNTMLVDAIHLTMTNRQQMQTWRKSRRL 569
N+ + L LT R Q +
Sbjct: 739 IQPLCIEPSCRVPCFSPRLLSTQARNQKPRKPKRPDL-----LTQQFRSLPQLVAEPTEA 793
Query: 570 MAYSTVGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNF 629
+ S VGT +Y+APEI +G+G DWW+ G ++YE L G PF +ET ++
Sbjct: 794 RSNSFVGTHEYLAPEIIKGEGHGAAVDWWTFGVLLYELLYGKTPFKGYDNEETLSNVV-- 851
Query: 630 EQTLQFPDDIHISYEAEDLIRRLLTHS-ENRLGRHGGADEIKAHPFFSGVDWNTIRQVEA 688
Q L+FPD +S++A++LIRRLL E+RLG GA EIK HPFF G++W IR
Sbjct: 852 YQNLKFPDSPLVSFQAKELIRRLLVKDPESRLGSEKGAAEIKRHPFFEGLNWALIRCAIP 911
Query: 689 PYIPKL 694
P +P +
Sbjct: 912 PELPDI 917
>At5g40030 [R] KOG0610 Putative serine/threonine protein kinase
Length = 499
Score = 179 bits (453), Expect = 2e-44
Identities = 122/362 (33%), Positives = 177/362 (48%), Gaps = 29/362 (8%)
Query: 347 FNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDSPW 406
F +K +G G G V L + ++ G +AMK + K + + +L + ER++L D P+
Sbjct: 114 FRLLKKLGCGDIGSVYLAELREMGCFFAMKVMDKGMLIGRKKLVRAQTEREILGLLDHPF 173
Query: 407 VVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRW--QIFTEDVTRFYMAECILAIEVIHKL 464
+ +LY F+ ++ L+MEF GGDL + + + F+E RFY +E +LA+E +H +
Sbjct: 174 LPTLYSHFETEKFSCLLMEFCSGGDLHILRQKQPGKHFSELAARFYASEVLLALEYLHMM 233
Query: 465 GFIHRDIKPDNILIDIRGHIKLSDFGL------------STGFHKTHDSSYYXXXXXXXX 512
G ++RD+KP+N+++ GHI LSDF L ST H +SY
Sbjct: 234 GVVYRDLKPENVMVREDGHIMLSDFDLSLQSFVSPTLIQSTSQPSCHIASYCIQPPCIDP 293
Query: 513 XXXXXXXXXXXXXXXXXXXXXPNETNNGNRNTMLVDAIHLTMTNRQQMQTWRKSRRLMAY 572
P NN R A ++ T +S
Sbjct: 294 SCKLPVACIQPSCFK------PRFLNNKPRKAKTEKAGSDSLPMLIAEPTAARSM----- 342
Query: 573 STVGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQT 632
S VGT +Y+APEI G+G DWW+ G +YE L G PF +ET ++ Q
Sbjct: 343 SFVGTHEYLAPEIIRGDGHGSSVDWWTFGIFLYELLTGKTPFKGNGNRETLFNVVG--QP 400
Query: 633 LQFPDDIHISYEAEDLIRRLLTHS-ENRLGRHGGADEIKAHPFFSGVDWNTIRQVEAPYI 691
L+FP+ IS+ A+DLIR LLT + RLG GA EIK HPFF+ V+W IR P I
Sbjct: 401 LKFPEG-SISFAAKDLIRGLLTKDPKKRLGFKKGATEIKQHPFFNNVNWALIRSTTPPEI 459
Query: 692 PK 693
PK
Sbjct: 460 PK 461
>Hs4885583 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1354
Score = 176 bits (447), Expect = 9e-44
Identities = 86/193 (44%), Positives = 128/193 (65%), Gaps = 2/193 (1%)
Query: 306 LESELASQDWSEERKNRQLAS-LGKKESQFXXXXXXXXXXDDFNSVKVIGKGAFGEVRLV 364
L++ + D+ RKN+ + + L + + +D+ VKVIG+GAFGEV+LV
Sbjct: 34 LDALVYDLDFPALRKNKNIDNFLSRYKDTINKIRDLRMKAEDYEVVKVIGRGAFGEVQLV 93
Query: 365 QKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDSPWVVSLYYSFQDSQYLYLIM 424
+ K T K+YAMK L K EM + A ERD++A ++SPWVV L+Y+FQD +YLY++M
Sbjct: 94 RHKSTRKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANSPWVVQLFYAFQDDRYLYMVM 153
Query: 425 EFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKLGFIHRDIKPDNILIDIRGHI 484
E++PGGDL+ ++ + + E RFY AE +LA++ IH +GFIHRD+KPDN+L+D GH+
Sbjct: 154 EYMPGGDLVNLMSNYDV-PEKWARFYTAEVVLALDAIHSMGFIHRDVKPDNMLLDKSGHL 212
Query: 485 KLSDFGLSTGFHK 497
KL+DFG +K
Sbjct: 213 KLADFGTCMKMNK 225
Score = 139 bits (351), Expect = 1e-32
Identities = 88/225 (39%), Positives = 118/225 (52%), Gaps = 24/225 (10%)
Query: 543 NTMLVDAIHLTMTNRQQMQTWRKSRRLMAYSTVGTPDYIAPEIFLYQG----YGQECDWW 598
N +L + HL + + K + + VGTPDYI+PE+ QG YG+ECDWW
Sbjct: 203 NMLLDKSGHLKLADFGTCMKMNKEGMVRCDTAVGTPDYISPEVLKSQGGDGYYGRECDWW 262
Query: 599 SLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQFPDDIHISYEAEDLIRRLLTHSEN 658
S+G +YE L+G PF +++ TY KIMN + +L FPDD IS EA++LI LT E
Sbjct: 263 SVGVFLYEMLVGDTPFYADSLVGTYSKIMNHKNSLTFPDDNDISKEAKNLICAFLTDREV 322
Query: 659 RLGRHGGADEIKAHPFFSGVD--WNTIRQVEAPYIPKLSSVTDTRFFPTDELENVPDSPX 716
RLGR+ G +EIK H FF W T+R AP +P LSS DT F D+LE
Sbjct: 323 RLGRN-GVEEIKRHLFFKNDQWAWETLRDTVAPVVPDLSSDIDTSNF--DDLEE------ 373
Query: 717 XXXXXXXXXXXXXXXXGVPQSNAKEDLPFIGYT-YSRFDYLTRKN 760
+P++ LPF+G+T YS YL+ N
Sbjct: 374 --------DKGEEETFPIPKAFVGNQLPFVGFTYYSNRRYLSSAN 410
>Hs4759044 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1388
Score = 172 bits (436), Expect = 2e-42
Identities = 84/186 (45%), Positives = 125/186 (67%), Gaps = 2/186 (1%)
Query: 306 LESELASQDWSEERKNRQLAS-LGKKESQFXXXXXXXXXXDDFNSVKVIGKGAFGEVRLV 364
L S + D+ RKN+ + + L + E +D++ VKVIG+GAFGEV+LV
Sbjct: 50 LNSLVLDLDFPALRKNKNIDNFLNRYEKIVKKIKGLQMKAEDYDVVKVIGRGAFGEVQLV 109
Query: 365 QKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDSPWVVSLYYSFQDSQYLYLIM 424
+ K + K+YAMK L K EM + A ERD++A ++SPWVV L+Y+FQD +YLY++M
Sbjct: 110 RHKASQKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANSPWVVQLFYAFQDDRYLYMVM 169
Query: 425 EFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKLGFIHRDIKPDNILIDIRGHI 484
E++PGGDL+ ++ + + E +FY AE +LA++ IH +G IHRD+KPDN+L+D GH+
Sbjct: 170 EYMPGGDLVNLMSNYDV-PEKWAKFYTAEVVLALDAIHSMGLIHRDVKPDNMLLDKHGHL 228
Query: 485 KLSDFG 490
KL+DFG
Sbjct: 229 KLADFG 234
Score = 134 bits (337), Expect = 5e-31
Identities = 77/190 (40%), Positives = 109/190 (56%), Gaps = 23/190 (12%)
Query: 573 STVGTPDYIAPEIFLYQG----YGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMN 628
+ VGTPDYI+PE+ QG YG+ECDWWS+G +YE L+G PF +++ TY KIM+
Sbjct: 249 TAVGTPDYISPEVLKSQGGDGFYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMD 308
Query: 629 FEQTLQFPDDIHISYEAEDLIRRLLTHSENRLGRHGGADEIKAHPFFSGVD--WNTIRQV 686
+ +L FP+D IS A++LI LT E RLGR+ G +EI+ HPFF W+ IR+
Sbjct: 309 HKNSLCFPEDAEISKHAKNLICAFLTDREVRLGRN-GVEEIRQHPFFKNDQWHWDNIRET 367
Query: 687 EAPYIPKLSSVTDTRFFPTDELENVPDSPXXXXXXXXXXXXXXXXXGVPQSNAKEDLPFI 746
AP +P+LSS D+ F D++E+ +P++ LPFI
Sbjct: 368 AAPVVPELSSDIDSSNF--DDIED--------------DKGDVETFPIPKAFVGNQLPFI 411
Query: 747 GYTYSRFDYL 756
G+TY R + L
Sbjct: 412 GFTYYRENLL 421
>Hs20536595 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1388
Score = 172 bits (436), Expect = 2e-42
Identities = 84/186 (45%), Positives = 125/186 (67%), Gaps = 2/186 (1%)
Query: 306 LESELASQDWSEERKNRQLAS-LGKKESQFXXXXXXXXXXDDFNSVKVIGKGAFGEVRLV 364
L S + D+ RKN+ + + L + E +D++ VKVIG+GAFGEV+LV
Sbjct: 50 LNSLVLDLDFPALRKNKNIDNFLNRYEKIVKKIRGLQMKAEDYDVVKVIGRGAFGEVQLV 109
Query: 365 QKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDSPWVVSLYYSFQDSQYLYLIM 424
+ K + K+YAMK L K EM + A ERD++A ++SPWVV L+Y+FQD +YLY++M
Sbjct: 110 RHKASQKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANSPWVVQLFYAFQDDRYLYMVM 169
Query: 425 EFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKLGFIHRDIKPDNILIDIRGHI 484
E++PGGDL+ ++ + + E +FY AE +LA++ IH +G IHRD+KPDN+L+D GH+
Sbjct: 170 EYMPGGDLVNLMSNYDV-PEKWAKFYTAEVVLALDAIHSMGLIHRDVKPDNMLLDKHGHL 228
Query: 485 KLSDFG 490
KL+DFG
Sbjct: 229 KLADFG 234
Score = 134 bits (337), Expect = 5e-31
Identities = 77/190 (40%), Positives = 109/190 (56%), Gaps = 23/190 (12%)
Query: 573 STVGTPDYIAPEIFLYQG----YGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMN 628
+ VGTPDYI+PE+ QG YG+ECDWWS+G +YE L+G PF +++ TY KIM+
Sbjct: 249 TAVGTPDYISPEVLKSQGGDGFYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMD 308
Query: 629 FEQTLQFPDDIHISYEAEDLIRRLLTHSENRLGRHGGADEIKAHPFFSGVD--WNTIRQV 686
+ +L FP+D IS A++LI LT E RLGR+ G +EI+ HPFF W+ IR+
Sbjct: 309 HKNSLCFPEDAEISKHAKNLICAFLTDREVRLGRN-GVEEIRQHPFFKNDQWHWDNIRET 367
Query: 687 EAPYIPKLSSVTDTRFFPTDELENVPDSPXXXXXXXXXXXXXXXXXGVPQSNAKEDLPFI 746
AP +P+LSS D+ F D++E+ +P++ LPFI
Sbjct: 368 AAPVVPELSSDIDSSNF--DDIED--------------DKGDVETFPIPKAFVGNQLPFI 411
Query: 747 GYTYSRFDYL 756
G+TY R + L
Sbjct: 412 GFTYYRENLL 421
>Hs16357474_1 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1530
Score = 167 bits (422), Expect = 7e-41
Identities = 76/147 (51%), Positives = 111/147 (74%), Gaps = 1/147 (0%)
Query: 345 DDFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDS 404
+DF +KVIG+GAFGEV +V+ K+T +IYAMK L K EM + + A + ERDVL D
Sbjct: 74 EDFEIIKVIGRGAFGEVAVVKMKNTERIYAMKILNKWEMLKRAETACFREERDVLVNGDC 133
Query: 405 PWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQ-IFTEDVTRFYMAECILAIEVIHK 463
W+ +L+Y+FQD +LYL+M++ GGDL+T+L +++ ED+ RFY+ E +LAI+ IH+
Sbjct: 134 QWITALHYAFQDENHLYLVMDYYVGGDLLTLLSKFEDKLPEDMARFYIGEMVLAIDSIHQ 193
Query: 464 LGFIHRDIKPDNILIDIRGHIKLSDFG 490
L ++HRDIKPDN+L+D+ GHI+L+DFG
Sbjct: 194 LHYVHRDIKPDNVLLDVNGHIRLADFG 220
Score = 140 bits (354), Expect = 6e-33
Identities = 83/185 (44%), Positives = 107/185 (56%), Gaps = 25/185 (13%)
Query: 575 VGTPDYIAPEIF--LYQG---YGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNF 629
VGTPDYI+PEI + G YG ECDWWSLG MYE L G PF +E+ ETY KIMN
Sbjct: 237 VGTPDYISPEILQAMEDGMGKYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNH 296
Query: 630 EQTLQFPDDI-HISYEAEDLIRRLLTHSENRLGRHGGADEIKAHPFFSGVDWNTIRQVEA 688
E+ QFP + +S EA+DLI+RL+ E RLG++ G ++ K H FF G++W IR +EA
Sbjct: 297 EERFQFPSHVTDVSEEAKDLIQRLICSRERRLGQN-GIEDFKKHAFFEGLNWENIRNLEA 355
Query: 689 PYIPKLSSVTDTRFFPTDE--LENVPDSPXXXXXXXXXXXXXXXXXGVPQSNAKEDLPFI 746
PYIP +SS +DT F D+ L N P G + LPFI
Sbjct: 356 PYIPDVSSPSDTSNFDVDDDVLRNTEILP----------------PGSHTGFSGLHLPFI 399
Query: 747 GYTYS 751
G+T++
Sbjct: 400 GFTFT 404
>Hs10334852 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 623
Score = 163 bits (413), Expect = 8e-40
Identities = 73/147 (49%), Positives = 110/147 (74%), Gaps = 1/147 (0%)
Query: 345 DDFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDS 404
DDF +KVIG+GAF EV +V+ K TG++YAMK + K +M + +++ + ERDVL D
Sbjct: 69 DDFEILKVIGRGAFSEVAVVKMKQTGQVYAMKIMNKWDMLKRGEVSCFREERDVLVNGDR 128
Query: 405 PWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRW-QIFTEDVTRFYMAECILAIEVIHK 463
W+ L+++FQD YLYL+ME+ GGDL+T+L ++ + ++ RFY+AE ++AI+ +H+
Sbjct: 129 RWITQLHFAFQDENYLYLVMEYYVGGDLLTLLSKFGERIPAEMARFYLAEIVMAIDSVHR 188
Query: 464 LGFIHRDIKPDNILIDIRGHIKLSDFG 490
LG++HRDIKPDNIL+D GHI+L+DFG
Sbjct: 189 LGYVHRDIKPDNILLDRCGHIRLADFG 215
Score = 121 bits (304), Expect = 3e-27
Identities = 75/217 (34%), Positives = 102/217 (46%), Gaps = 24/217 (11%)
Query: 543 NTMLVDAIHLTMTNRQQMQTWRKSRRLMAYSTVGTPDYIAPEIFLYQG-------YGQEC 595
N +L H+ + + R + + VGTPDY++PEI G YG EC
Sbjct: 200 NILLDRCGHIRLADFGSCLKLRADGTVRSLVAVGTPDYLSPEILQAVGGGPGTGSYGPEC 259
Query: 596 DWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQFP-DDIHISYEAEDLIRRLLT 654
DWW+LG YE G PF +++ ETY KI+++++ L P D + EA D I+RLL
Sbjct: 260 DWWALGVFAYEMFYGQTPFYADSTAETYGKIVHYKEHLSLPLVDEGVPEEARDFIQRLLC 319
Query: 655 HSENRLGRHGGADEIKAHPFFSGVDWNTIRQVEAPYIPKLSSVTDTRFFPTDELENVPDS 714
E RLGR GGA + + HPFF G+DW+ +R P+ P TDT F E
Sbjct: 320 PPETRLGR-GGAGDFRTHPFFFGLDWDGLRDSVPPFTPDFEGATDTCNFDLVE------- 371
Query: 715 PXXXXXXXXXXXXXXXXXGVPQSNAKEDLPFIGYTYS 751
G P LPF+GY+YS
Sbjct: 372 -----DGLTAMTLSDIREGAPLG---VHLPFVGYSYS 400
>CE11916 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1548
Score = 163 bits (413), Expect = 8e-40
Identities = 88/221 (39%), Positives = 136/221 (60%), Gaps = 6/221 (2%)
Query: 276 DKAAAVKLK-IENFYQSSVGYAIERNQRRLELESELASQDW---SEERKNRQLASLGKK- 330
D +A V+LK +EN Y E ++S + D S RK + +A +
Sbjct: 7 DDSAPVRLKTLENIYMDGPSKKPEALSFETLIDSLICLYDECCNSTLRKEKCIAEFVESV 66
Query: 331 ESQFXXXXXXXXXXDDFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLA 390
++ DDF +KVIGKGAFGEV +V+ + G+IYAMK L K EM + + A
Sbjct: 67 KTVISKAKKLRLSRDDFEVLKVIGKGAFGEVAVVRMRGVGEIYAMKILNKWEMVKRAETA 126
Query: 391 HVKAERDVLAGSDSPWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRW-QIFTEDVTRF 449
+ ERDVL D W+ +L+Y+FQD + LY +M++ GGD++T+L ++ E + +F
Sbjct: 127 CFREERDVLVYGDRRWITNLHYAFQDEKNLYFVMDYYIGGDMLTLLSKFVDHIPESMAKF 186
Query: 450 YMAECILAIEVIHKLGFIHRDIKPDNILIDIRGHIKLSDFG 490
Y+AE +LAI+ +H+LG++HRD+KPDN+L+D++GHI+L+DFG
Sbjct: 187 YIAEMVLAIDSLHRLGYVHRDVKPDNVLLDMQGHIRLADFG 227
Score = 140 bits (353), Expect = 7e-33
Identities = 75/144 (52%), Positives = 94/144 (65%), Gaps = 9/144 (6%)
Query: 575 VGTPDYIAPEIF--LYQG---YGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNF 629
VGTPDYI+PEI + G YG+ECDWWSLG MYE L G PF SE +TY KIM+
Sbjct: 244 VGTPDYISPEILRAMEDGRGRYGKECDWWSLGICMYEMLYGTTPFYSERLVDTYGKIMSH 303
Query: 630 EQTLQFPD---DIHISYEAEDLIRRLLTHSENRLGRHGGADEIKAHPFFSGVDWNTIRQV 686
+ L FPD D +S EA+DLIR+L+ S+ R GR+G +D + HPFF G+DWNTIR
Sbjct: 304 QDMLDFPDDEIDWVVSEEAKDLIRQLICSSDVRFGRNGLSD-FQLHPFFEGIDWNTIRDS 362
Query: 687 EAPYIPKLSSVTDTRFFPTDELEN 710
PY+P++SS DT F D E+
Sbjct: 363 NPPYVPEVSSPEDTSNFDVDVCED 386
>Hs4505831 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 496
Score = 162 bits (411), Expect = 1e-39
Identities = 74/147 (50%), Positives = 111/147 (75%), Gaps = 1/147 (0%)
Query: 345 DDFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDS 404
+DF +KVIG+GAFGEV +V+ K+ K++AMK L K EM + + A + ERDVL D+
Sbjct: 75 EDFEILKVIGRGAFGEVAVVKLKNADKVFAMKILNKWEMLKRAETACFREERDVLVNGDN 134
Query: 405 PWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQ-IFTEDVTRFYMAECILAIEVIHK 463
W+ +L+Y+FQD LYL+M++ GGDL+T+L +++ ED+ RFY+AE ++AI+ +H+
Sbjct: 135 KWITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKFEDRLPEDMARFYLAEMVIAIDSVHQ 194
Query: 464 LGFIHRDIKPDNILIDIRGHIKLSDFG 490
L ++HRDIKPDNIL+D+ GHI+L+DFG
Sbjct: 195 LHYVHRDIKPDNILMDMNGHIRLADFG 221
Score = 151 bits (382), Expect = 3e-36
Identities = 87/196 (44%), Positives = 115/196 (58%), Gaps = 25/196 (12%)
Query: 575 VGTPDYIAPEIF--LYQG---YGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNF 629
VGTPDYI+PEI + G YG ECDWWSLG MYE L G PF +E+ ETY KIMN
Sbjct: 238 VGTPDYISPEILQAMEDGKGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNH 297
Query: 630 EQTLQFPDDI-HISYEAEDLIRRLLTHSENRLGRHGGADEIKAHPFFSGVDWNTIRQVEA 688
++ QFP + +S A+DLIRRL+ E+RLG++ G ++ K HPFFSG+DW+ IR EA
Sbjct: 298 KERFQFPAQVTDVSENAKDLIRRLICSREHRLGQN-GIEDFKKHPFFSGIDWDNIRNCEA 356
Query: 689 PYIPKLSSVTDTRFFPTDE--LENVPDSPXXXXXXXXXXXXXXXXXGVPQSNAKEDLPFI 746
PYIP++SS TDT F D+ L+N P + LPF+
Sbjct: 357 PYIPEVSSPTDTSNFDVDDDCLKNSETMPPPTHTAF----------------SGHHLPFV 400
Query: 747 GYTYSRFDYLTRKNAL 762
G+TY+ L+ ++ L
Sbjct: 401 GFTYTSSCVLSDRSCL 416
>SPBC725.06c [R] KOG0605 NDR and related serine/threonine kinases
Length = 1032
Score = 162 bits (409), Expect = 2e-39
Identities = 113/388 (29%), Positives = 178/388 (45%), Gaps = 37/388 (9%)
Query: 345 DDFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKA----ERDVLA 400
D+F +K I +GA+G V L +K+ +GK +A+K + KS + D L +K +R++
Sbjct: 526 DEFILLKEINRGAYGRVYLAKKRSSGKYFALKMIPKSSL---DSLKKIKGLLLEKRNMHI 582
Query: 401 GSDSPWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEV 460
P V LYY+F YL L+M++ GGD T++ + E Y AE + AIE+
Sbjct: 583 QRYGPNTVKLYYAFDSGDYLCLVMDYFNGGDCETLIQKLGPLPEQWVCQYAAELLNAIEL 642
Query: 461 IHKLGFIHRDIKPDNILIDIRGHIKLSDFGLS---------------TGFHKTHDSSYYX 505
+H+ G IH DIKP N+L+D GHI+L+DFGLS F + H + Y
Sbjct: 643 LHQDGIIHHDIKPANMLVDETGHIRLTDFGLSENVEEKKEVYKLTKRMSFEQKHGNLYEQ 702
Query: 506 XXXXXXXXXXXXXXXXXXXXXXXXXXXXPNETNNGNR----------NTMLVDAIHLTMT 555
++ N N M AIH+ M
Sbjct: 703 LQPKKFEFVRYVRNYRGNIDELEKAESPQQNSDYANDSVQHLLDFDINNMDETAIHMLMN 762
Query: 556 NRQQMQTWRKSRRLMAYSTVGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFC 615
++ +++R + GTP+Y+APEI + Q D W++G +++E L G PF
Sbjct: 763 QLEK----KENRTFIKKDISGTPNYMAPEILMGVD-TQMGDIWAMGCVIFEMLTGTRPFE 817
Query: 616 SETPQETYRKIMNFEQTLQFPDDIHISYEAEDLIRRLLTHSENRLGRHGGADEIKAHPFF 675
+ T + + +I + S EA DLI +L+ N+ G EIK HPFF
Sbjct: 818 ANTVKAIWARIERNDIGWTKRVKESCSKEAVDLITKLMDPDCNKRLGSNGYQEIKKHPFF 877
Query: 676 SGVDWNTIRQVEAPYIPKLSSVTDTRFF 703
+ W+ + P++P+ +V D +F
Sbjct: 878 RTIKWDNLNSGPGPFVPQTENVEDLTYF 905
>CE08098 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1173
Score = 160 bits (404), Expect = 9e-39
Identities = 73/145 (50%), Positives = 106/145 (72%), Gaps = 1/145 (0%)
Query: 346 DFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDSP 405
DF +KVIG+GAFGEV LV+ T +YAMK L K +M + A ERD++A ++S
Sbjct: 67 DFRQLKVIGRGAFGEVHLVRHTRTNTVYAMKMLNKDDMIKRADSAFFWEERDIMAHANSE 126
Query: 406 WVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKLG 465
W+V L Y+FQD ++LY++ME++PGGDL+ ++ +++ +E TRFY AE + A+ +H +G
Sbjct: 127 WIVRLQYAFQDPRHLYMVMEYMPGGDLVNLMTSYEV-SEKWTRFYTAEIVEALAALHSMG 185
Query: 466 FIHRDIKPDNILIDIRGHIKLSDFG 490
+IHRD+KPDN+LI I GHIKL+DFG
Sbjct: 186 YIHRDVKPDNMLISISGHIKLADFG 210
Score = 127 bits (319), Expect = 6e-29
Identities = 76/199 (38%), Positives = 110/199 (55%), Gaps = 29/199 (14%)
Query: 573 STVGTPDYIAPEIFLYQG----YGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMN 628
+ VGTPDYI+PE+ QG +G+E DWWS+G +YE L+G PF +E TY IMN
Sbjct: 225 TAVGTPDYISPEVLRNQGQDAEFGKEVDWWSVGVFIYEMLVGETPFYAEALVSTYTNIMN 284
Query: 629 FEQTLQFPDDIHISYEAEDLIRRLLTHSENRLGRHGGADEIKAHPFFSGVDWN--TIRQV 686
+ +L+FPD+ IS +A+D+I++ L+ + +RLGR+ D+I+ H FF +W T+R+
Sbjct: 285 HKTSLKFPDEPLISTQAKDIIKKFLSAAPDRLGRN-SVDDIRNHKFFVNDEWTFATLREA 343
Query: 687 EAPYIPKLSSVTDTRFF---PTDELENVPDSPXXXXXXXXXXXXXXXXXGVPQSNAKEDL 743
P IP L S DT F T + +N D +P++ L
Sbjct: 344 SPPVIPSLKSDDDTTHFEEIETRDRDNAGD------------------FQLPKTFNGNQL 385
Query: 744 PFIGYTYSRFDYLTRKNAL 762
PFIG+TYS +Y KN L
Sbjct: 386 PFIGFTYSN-EYSPVKNLL 403
>At3g14370 [R] KOG0610 Putative serine/threonine protein kinase
Length = 480
Score = 160 bits (404), Expect = 9e-39
Identities = 101/347 (29%), Positives = 169/347 (48%), Gaps = 34/347 (9%)
Query: 350 VKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDSPWVVS 409
++ +G G G V L +D+ +A+K + ++ + + +L+ V+ E ++L+ D P++ +
Sbjct: 91 IRHLGTGNLGRVFLCNLRDSSARFALKVIDRNCLTTEKKLSQVETEAEILSLLDHPFLPT 150
Query: 410 LYYSFQDSQYLYLIMEFLPGGDLMTMLIRW--QIFTEDVTRFYMAECILAIEVIHKLGFI 467
LY +S Y L++++ P GDL ++L + RF+ AE ++A+E +H +G +
Sbjct: 151 LYARIDESHYTCLLIDYAPNGDLHSLLRKQPGNRLPIQPVRFFAAEVLVALEYLHAMGIV 210
Query: 468 HRDIKPDNILIDIRGHIKLSDFGL--STGFHKTHDSSYYXXXXXXXXXXXXXXXXXXXXX 525
+RD+KP+N+L+ GH+ LSDF L + T S Y
Sbjct: 211 YRDLKPENVLLREDGHVMLSDFDLCFKSDVVPTFKSRRYRRSSSSPSLR----------- 259
Query: 526 XXXXXXXXPNETNNGNRNTMLVDAIHLTMTNRQQMQTWRKSRRLMAYST--VGTPDYIAP 583
R + R+++ + + + A+S VGT +Y+AP
Sbjct: 260 ---------------RRRSGCFSVAAEKKYEREEIVSEFAAEPVTAFSRSCVGTHEYLAP 304
Query: 584 EIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQFPDDIHISY 643
E+ G+G DWW+ G +YE L G PF E+ ++T R I++ +T F D +
Sbjct: 305 ELVSGNGHGSGVDWWAFGIFLYELLYGTTPFKGESKEQTLRNIVSTTKTASFHMDGDLD- 363
Query: 644 EAEDLIRRLLTHS-ENRLGRHGGADEIKAHPFFSGVDWNTIRQVEAP 689
EA DLI +LL RLG GA +IK HPFF G+ W IR + P
Sbjct: 364 EARDLIEKLLVKDPRKRLGCARGAQDIKRHPFFDGIKWPLIRHYKPP 410
>7291742_1 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1539
Score = 159 bits (401), Expect = 2e-38
Identities = 75/147 (51%), Positives = 109/147 (74%), Gaps = 1/147 (0%)
Query: 345 DDFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDS 404
DDF+ +K+IG+GAFGEV +VQ T K+YAMK L K EM + + A + ERDVL D
Sbjct: 98 DDFDILKIIGRGAFGEVCVVQMISTEKVYAMKILNKWEMLKRAETACFREERDVLVFGDR 157
Query: 405 PWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQ-IFTEDVTRFYMAECILAIEVIHK 463
W+ +L+Y+FQD+ LYL+M++ GGDL+T+L +++ ED+ +FY+ E ILAI IH+
Sbjct: 158 QWITNLHYAFQDNINLYLVMDYYCGGDLLTLLSKFEDKLPEDMAKFYITEMILAINSIHQ 217
Query: 464 LGFIHRDIKPDNILIDIRGHIKLSDFG 490
+ ++HRDIKPDN+L+D RGH++L+DFG
Sbjct: 218 IRYVHRDIKPDNVLLDKRGHVRLADFG 244
Score = 129 bits (325), Expect = 1e-29
Identities = 80/223 (35%), Positives = 113/223 (49%), Gaps = 34/223 (15%)
Query: 543 NTMLVDAIHLTMTNRQQMQTWRKSRRLMAYSTVGTPDYIAPEIF--LYQG---YGQECDW 597
N +L H+ + + K + + VGTPDYI+PEI + G YG ECDW
Sbjct: 229 NVLLDKRGHVRLADFGSCLRLDKDGTVQSNVAVGTPDYISPEILRAMEDGKGRYGTECDW 288
Query: 598 WSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQFPDDIHISYE----AEDLIRRLL 653
WSLG MYE L G PF +E+ ETY KIMN + P ++Y+ ++DL+ +L+
Sbjct: 289 WSLGVCMYEMLYGETPFYAESLVETYGKIMNHQNCFNLPSQETLNYKVSETSQDLLCKLI 348
Query: 654 THSENRLGRHGGADEIKAHPFFSGVDWNTIRQVEAPYIPKLSSVTDTRFFPTDE-----L 708
ENRLG++ G + HP+F G+DW IRQ APY+P++SS TDT F D+
Sbjct: 349 CIPENRLGQN-GIQDFMDHPWFVGIDWKNIRQGPAPYVPEVSSPTDTSNFDVDDNDVRLT 407
Query: 709 ENVPDSPXXXXXXXXXXXXXXXXXGVPQSNAKEDLPFIGYTYS 751
+++P S LPFIG+T+S
Sbjct: 408 DSIPPSANPAFSGF-------------------HLPFIGFTFS 431
>At3g20830 [R] KOG0610 Putative serine/threonine protein kinase
Length = 408
Score = 157 bits (396), Expect = 8e-38
Identities = 110/361 (30%), Positives = 173/361 (47%), Gaps = 33/361 (9%)
Query: 345 DDFNSVKVIGKGAFGEVRL----VQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLA 400
D ++K++GKGA G V L V + +A+K + KS + L + E +VL
Sbjct: 19 DSIKALKILGKGATGTVFLAHDVVSTSSSSSPFAVKLVPKS---SASSLRRARWEIEVLR 75
Query: 401 -----GSDSPWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQ--IFTEDVTRFYMAE 453
+ +P++ L SF+ +Y + + GGDL +L R +F+ V RFY+AE
Sbjct: 76 RLSVDSNQNPFLPRLLASFESPEYFAWAVPYCSGGDLNVLLHRQNDGVFSSSVIRFYVAE 135
Query: 454 CILAIEVIHKLGFIHRDIKPDNILIDIRGHIKLSDFGLSTGFHKTHDSSYYXXXXXXXXX 513
+ A+E +H +G +RD+KP+NILI GH+ L+DF LS K +Y
Sbjct: 136 IVCALEHLHTMGIAYRDLKPENILIQQSGHVTLTDFDLSRSLKKPLRPHFY----QPDPE 191
Query: 514 XXXXXXXXXXXXXXXXXXXXPNETNNGNRNTMLVDAIHLTMTNRQQMQTWRKSRRLMAYS 573
N+T + V+ I+ T+ + + S
Sbjct: 192 LIIDRKKSRSFSRLISPTAEKNKTGLKKTRSARVNPINRRKTSFSSGE--------RSNS 243
Query: 574 TVGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTL 633
VGT +Y++PE+ G+ DWW+LG + YE + G PF ++ +ET+R ++ +
Sbjct: 244 FVGTDEYVSPEVIRGDGHDFAVDWWALGVLTYEMMYGETPFKGKSKKETFRNVL-----M 298
Query: 634 QFPDDIHISYEAEDLIRRLLTHSEN-RLGRHGGADEIKAHPFFSGVDWNTIRQV-EAPYI 691
+ P+ + DLIRRLL N RLG H GA EIK FF+GV W+ + +V P+I
Sbjct: 299 KEPEFAGKPNDLTDLIRRLLVKDPNRRLGCHRGAAEIKELAFFAGVRWDLLTEVLRPPFI 358
Query: 692 P 692
P
Sbjct: 359 P 359
>At2g34650 [R] KOG0610 Putative serine/threonine protein kinase
Length = 438
Score = 157 bits (396), Expect = 8e-38
Identities = 109/365 (29%), Positives = 168/365 (45%), Gaps = 45/365 (12%)
Query: 346 DFNSVKVIGKGAFGEVRLV-----QKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLA 400
DF ++ IG G G V L +++ +AMK + K + K ++ + E+ +L
Sbjct: 74 DFRLMRRIGAGDIGTVYLCRLAGDEEESRSSYFAMKVVDKEALALKKKMHRAEMEKTILK 133
Query: 401 GSDSPWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRW--QIFTEDVTRFYMAECILAI 458
D P++ +LY F+ S + ++ME+ GGDL ++ R + F+ RFY AE ++A+
Sbjct: 134 MLDHPFLPTLYAEFEASHFSCIVMEYCSGGDLHSLRHRQPHRRFSLSSARFYAAEVLVAL 193
Query: 459 EVIHKLGFIHRDIKPDNILIDIRGHIKLSDFGLSTGFHKTHDSSYYXXXXXXXXXXXXXX 518
E +H LG I+RD+KP+NIL+ GHI LSDF LS
Sbjct: 194 EYLHMLGIIYRDLKPENILVRSDGHIMLSDFDLS-------------------------L 228
Query: 519 XXXXXXXXXXXXXXXPNETNNGNRNTMLVDAIHLTMTNRQQMQTWRKSRRLMAY------ 572
N+ R + + + +++QT +R +A
Sbjct: 229 CSDSIAAVESSSSSPENQQLRSPRRFTRLARLFQRVLRSKKVQTLEPTRLFVAEPVTARS 288
Query: 573 -STVGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQ 631
S VGT +Y+APE+ +G DWW+ G +YE + G PF + T R I+ ++
Sbjct: 289 GSFVGTHEYVAPEVASGGSHGNAVDWWAFGVFLYEMIYGKTPFVAPTNDVILRNIV--KR 346
Query: 632 TLQFPDD---IHISYEAEDLIRRLLTHS-ENRLGRHGGADEIKAHPFFSGVDWNTIRQVE 687
L FP D A +LI LL RLG GA E+K HPFF G+++ IR +
Sbjct: 347 QLSFPTDSPATMFELHARNLISGLLNKDPTKRLGSRRGAAEVKVHPFFKGLNFALIRTLT 406
Query: 688 APYIP 692
P IP
Sbjct: 407 PPEIP 411
>7293249 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1390
Score = 156 bits (394), Expect = 1e-37
Identities = 69/146 (47%), Positives = 109/146 (74%), Gaps = 1/146 (0%)
Query: 345 DDFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDS 404
+DF+ +K+IG GAFGEV+LV+ K + ++YAMK L K EM + A ER ++A ++S
Sbjct: 85 EDFHFIKLIGAGAFGEVQLVRHKSSSQVYAMKRLSKFEMMKRPDSAFFWEERHIMAHANS 144
Query: 405 PWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKL 464
W+V L+++FQD++YLY++M+F+PGGD+++++ + I E FY E +LA++ IH +
Sbjct: 145 EWIVQLHFAFQDAKYLYMVMDFMPGGDIVSLMGDYDI-PEKWAIFYTMEVVLALDTIHNM 203
Query: 465 GFIHRDIKPDNILIDIRGHIKLSDFG 490
GF+HRD+KPDN+L+D GH+KL+DFG
Sbjct: 204 GFVHRDVKPDNMLLDSYGHLKLADFG 229
Score = 139 bits (351), Expect = 1e-32
Identities = 82/216 (37%), Positives = 120/216 (54%), Gaps = 24/216 (11%)
Query: 543 NTMLVDAI-HLTMTNRQQMQTWRKSRRLMAYSTVGTPDYIAPEIFLYQG----YGQECDW 597
+ ML+D+ HL + + + ++++ + VGTPDYI+PE+ QG YG+ECDW
Sbjct: 213 DNMLLDSYGHLKLADFGTCMRMGANGQVVSSNAVGTPDYISPEVLQSQGVDNEYGRECDW 272
Query: 598 WSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQFPDDIHISYEAEDLIRRLLTHSE 657
WS+G +YE L G PF +++ TY KIM+ + +L FP ++ IS +A+ LIR LT
Sbjct: 273 WSVGIFLYEMLFGETPFYADSLVGTYGKIMDHKNSLSFPPEVEISEQAKALIRAFLTDRT 332
Query: 658 NRLGRHGGADEIKAHPFFSGVDW--NTIRQVEAPYIPKLSSVTDTRFFPTDELENVPDSP 715
RLGR+ G ++IKAHPFF W + IR+ P +P+LSS DTR F E + P+
Sbjct: 333 QRLGRY-GIEDIKAHPFFRNDTWSFDNIRESVPPVVPELSSDDDTRNFEDIERDEKPEE- 390
Query: 716 XXXXXXXXXXXXXXXXXGVPQSNAKEDLPFIGYTYS 751
VP+ LPFIG+TY+
Sbjct: 391 ---------------VFPVPKGFDGNHLPFIGFTYT 411
>At3g08720 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 471
Score = 155 bits (392), Expect = 2e-37
Identities = 72/158 (45%), Positives = 108/158 (67%)
Query: 345 DDFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDS 404
+DF +KV+G+GAFG+V V+KKDT +IYAMK + K ++ K+ ++KAERD+L D
Sbjct: 138 EDFEVLKVVGQGAFGKVYQVRKKDTSEIYAMKVMRKDKIVEKNHAEYMKAERDILTKIDH 197
Query: 405 PWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKL 464
P++V L YSFQ LYL+++F+ GG L L +F ED+ R Y AE + A+ +H+
Sbjct: 198 PFIVQLKYSFQTKYRLYLVLDFINGGHLFFQLYHQGLFREDLARVYTAEIVSAVSHLHEK 257
Query: 465 GFIHRDIKPDNILIDIRGHIKLSDFGLSTGFHKTHDSS 502
G +HRD+KP+NIL+D+ GH+ L+DFGL+ F + S+
Sbjct: 258 GIMHRDLKPENILMDVDGHVMLTDFGLAKEFEENTRSN 295
Score = 77.8 bits (190), Expect = 6e-14
Identities = 64/209 (30%), Positives = 101/209 (47%), Gaps = 33/209 (15%)
Query: 551 HLTMTNRQQMQTWRKSRRLMAYSTVGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIG 610
H+ +T+ + + ++ R + S GT +Y+APEI +G+ + DWWS+G ++YE L G
Sbjct: 276 HVMLTDFGLAKEFEENTR--SNSMCGTTEYMAPEIVRGKGHDKAADWWSVGILLYEMLTG 333
Query: 611 WPPFCSETPQETYRKIMNFEQTLQFPDDIHISYEAEDLIRRLL-THSENRLGR-HGGADE 668
PPF + + + + + QF +S EA L++ LL E RLG GA+E
Sbjct: 334 KPPFLGSKGKIQQKIVKDKIKLPQF-----LSNEAHALLKGLLQKEPERRLGSGPSGAEE 388
Query: 669 IKAHPFFSGVDWNTI--RQVEAPYIPKLSSVTDTRFFP---TDELENVPDSPXXXXXXXX 723
IK H +F ++W + R+V+ + P +S F TD +V DSP
Sbjct: 389 IKKHKWFKAINWKKLEAREVQPSFKPAVSGRQCIANFDKCWTD--MSVLDSPASS----- 441
Query: 724 XXXXXXXXXGVPQSNAKEDLPFIGYTYSR 752
P S+AK + PF +TY R
Sbjct: 442 -----------PNSDAKAN-PFTNFTYVR 458
>At3g08730 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 465
Score = 155 bits (391), Expect = 3e-37
Identities = 73/158 (46%), Positives = 106/158 (66%)
Query: 345 DDFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDS 404
DDF +KV+GKGAFG+V V+KK+T +IYAMK + K + K+ ++KAERD+L D
Sbjct: 132 DDFEVMKVVGKGAFGKVYQVRKKETSEIYAMKVMRKDHIMEKNHAEYMKAERDILTKIDH 191
Query: 405 PWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKL 464
P++V L YSFQ LYL+++F+ GG L L +F ED+ R Y AE + A+ +H+
Sbjct: 192 PFIVQLKYSFQTKYRLYLVLDFINGGHLFFQLYHQGLFREDLARVYTAEIVSAVSHLHEK 251
Query: 465 GFIHRDIKPDNILIDIRGHIKLSDFGLSTGFHKTHDSS 502
G +HRD+KP+NIL+D GH+ L+DFGL+ F + S+
Sbjct: 252 GIMHRDLKPENILMDTDGHVMLTDFGLAKEFEENTRSN 289
Score = 76.6 bits (187), Expect = 1e-13
Identities = 63/209 (30%), Positives = 101/209 (48%), Gaps = 33/209 (15%)
Query: 551 HLTMTNRQQMQTWRKSRRLMAYSTVGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIG 610
H+ +T+ + + ++ R + S GT +Y+APEI +G+ + DWWS+G ++YE L G
Sbjct: 270 HVMLTDFGLAKEFEENTR--SNSMCGTTEYMAPEIVRGKGHDKAADWWSVGILLYEMLTG 327
Query: 611 WPPFCSETPQETYRKIMNFEQTLQFPDDIHISYEAEDLIRRLL-THSENRLGRH-GGADE 668
PPF + + + + + QF +S EA +++ LL E RLG GA+E
Sbjct: 328 KPPFLGSKGKIQQKIVKDKIKLPQF-----LSNEAHAILKGLLQKEPERRLGSGLSGAEE 382
Query: 669 IKAHPFFSGVDWNTI--RQVEAPYIPKLSSVTDTRFFP---TDELENVPDSPXXXXXXXX 723
IK H +F G++W + R+V + P++S F TD +V DSP
Sbjct: 383 IKQHKWFKGINWKKLEAREVMPSFKPEVSGRQCIANFDKCWTD--MSVLDSPASS----- 435
Query: 724 XXXXXXXXXGVPQSNAKEDLPFIGYTYSR 752
P S+ K + PF +TY R
Sbjct: 436 -----------PSSDPKAN-PFTNFTYVR 452
>SPAC22E12.14c [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 646
Score = 153 bits (386), Expect = 1e-36
Identities = 72/151 (47%), Positives = 110/151 (72%), Gaps = 3/151 (1%)
Query: 345 DDFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVL---AG 401
DDF +K+IGKG FG+V LV+KKDT ++YAMK L K + + ++AH ERD+L +
Sbjct: 264 DDFVPLKLIGKGTFGQVYLVRKKDTERVYAMKVLSKKVIVRRKEVAHTVGERDILVQTSA 323
Query: 402 SDSPWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVI 461
+DSP++V+L +SFQ + LYL+ +++ GG+L L + F E+ +FY+AE +LA++ +
Sbjct: 324 ADSPFIVALRFSFQTPKDLYLVTDYMAGGELFWHLQKSVRFPEERAKFYIAELLLALQAL 383
Query: 462 HKLGFIHRDIKPDNILIDIRGHIKLSDFGLS 492
HK G ++RD+KP+NIL+D++GHI L DFGLS
Sbjct: 384 HKRGIVYRDLKPENILLDVQGHIALCDFGLS 414
Score = 100 bits (249), Expect = 8e-21
Identities = 51/135 (37%), Positives = 81/135 (59%), Gaps = 7/135 (5%)
Query: 576 GTPDYIAPEIFLYQ-GYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQ 634
GT DY+APE+ L + GY D+WSLG ++YE GW PF ++ Q+ Y+ I+ + ++
Sbjct: 429 GTTDYLAPEVILDEAGYDMMVDFWSLGVLLYEMTCGWSPFYADNTQQLYKNIVFGK--VR 486
Query: 635 FPDDIHISYEAEDLIRRLLTHS-ENRLGRHGGADEIKAHPFFSGVDWNTI--RQVEAPYI 691
FP + +S EA DLI+ LL + ++RLG HG +E+ HPFF G+DW + +++ P+
Sbjct: 487 FPRGL-LSVEARDLIKLLLNRNPKHRLGAHGDVEEVMKHPFFDGIDWKKLAAKEISPPFK 545
Query: 692 PKLSSVTDTRFFPTD 706
P + D F +
Sbjct: 546 PIVEGEIDVSNFDVE 560
>7294566 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1252
Score = 152 bits (385), Expect = 1e-36
Identities = 72/146 (49%), Positives = 106/146 (72%), Gaps = 4/146 (2%)
Query: 345 DDFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDS 404
DDF +IG+G FG V LV ++ T IYAMK + KS + + VK ERD+++ +S
Sbjct: 111 DDFLIKTLIGQGYFGNVHLVVERQTNDIYAMKKIKKSVVTT----SQVKEERDIMSIRNS 166
Query: 405 PWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKL 464
W+++L Y+FQD+ LYL+ME++PGGDL++++ R F ED+ RFY+AE +A+ +H++
Sbjct: 167 EWLINLQYAFQDNDNLYLVMEYMPGGDLLSLMSRHGPFDEDLARFYLAELTVALHTLHEM 226
Query: 465 GFIHRDIKPDNILIDIRGHIKLSDFG 490
G++HRDIKP+NILID GHIKL+DFG
Sbjct: 227 GYVHRDIKPENILIDRFGHIKLADFG 252
Score = 95.5 bits (236), Expect = 3e-19
Identities = 64/221 (28%), Positives = 96/221 (42%), Gaps = 26/221 (11%)
Query: 545 MLVDAI-HLTMTNRQQMQTWRKSRRLMAYSTVGTPDYIAPEIFLYQG--------YGQEC 595
+L+D H+ + + + +++ S VGTPDYIAPE+ + C
Sbjct: 238 ILIDRFGHIKLADFGNAAALDRDGHVLSLSPVGTPDYIAPELLQTISTYKLSKSMHDVSC 297
Query: 596 DWWSLGAIMYECLIGWPPFCSETPQETYRKIM------NFEQTLQFPDDIHISYEAEDLI 649
D+WS+G I YE + PF + ETY KI+ + ++ + FP D+ +S +LI
Sbjct: 298 DYWSMGIIGYELICETTPFHEDNVHETYSKILSHCEESHLKELISFPADLKVSVNYRNLI 357
Query: 650 RRLLTHSENRLGRHGGADEIKAHPFFSGVDWNTIRQVEAPYIPKLSSVTDTRFFPTDELE 709
L+T+ RL + IK HPFFS + W +IR P IP + S DT F
Sbjct: 358 ESLVTNPSKRL----SYERIKNHPFFSEIPWGSIRSQVPPIIPTVRSDDDTSNFEDGIRH 413
Query: 710 NVPDSPXXXXXXXXXXXXXXXXXGVPQSNAKEDLPFIGYTY 750
G +DLPFIGY++
Sbjct: 414 KTRREQGVAKKSLTTNMKSNDFSG-------KDLPFIGYSF 447
>At3g44610 [R] KOG0610 Putative serine/threonine protein kinase
Length = 472
Score = 152 bits (383), Expect = 2e-36
Identities = 110/382 (28%), Positives = 169/382 (43%), Gaps = 47/382 (12%)
Query: 353 IGKGAFGEVRLVQKKDTGKI----------YAMKTLLKSEMYNKDQLAHVKAERDVLAGS 402
+G G G V L + K + A K + K E+ ++ + K ER++L
Sbjct: 75 LGSGDIGSVFLAEFKSLTAVTETTAVKLPLLAAKVMDKKELASRSKEGRAKTEREILESL 134
Query: 403 DSPWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRW--QIFTEDVTRFYMAECILAIEV 460
D P++ +LY + ++L L+ EF PGGDL + + + F E RFY++E I+AIE
Sbjct: 135 DHPFLPTLYAAIDSPKWLCLLTEFCPGGDLHVLRQKQTHKRFHESAVRFYVSEVIVAIEY 194
Query: 461 IHKLGFIHRDIKPDNILIDIRGHIKLSDFGLSTGFHKTHDSSYYXXXXXXXXXXXXXXXX 520
+H LG ++RD+KP+N+L+ GHI L+DF LS K +S+
Sbjct: 195 LHMLGIVYRDLKPENVLVRSDGHIMLTDFDLSL---KCDESTSTPQIVLNRNNLPNGSSD 251
Query: 521 XXXXXXXXXXXXXPNETNNGNRNTMLVDAIHLTMTNRQQMQTWRKSR--------RLMAY 572
+ N V H + R++ R + + +
Sbjct: 252 QNENQGMDHRQTTSSSCMIPNCIVPAVSCFHPRIRRRKKKTDHRNNGPELVAEPVDVRSM 311
Query: 573 STVGTPDYIAPEI----FLY-----------------QGYGQECDWWSLGAIMYECLIGW 611
S VGT +Y+APEI +Y +G+G DWW+LG M+E G
Sbjct: 312 SFVGTHEYLAPEIVSVYIMYNFPMWYPNMKRKMWMAGEGHGSAVDWWTLGIFMFELFYGT 371
Query: 612 PPFCSETPQETYRKIMNFEQTLQFPDDIHISYEAEDLIRRLLTHS-ENRLGRHGGADEIK 670
PF + T I+ + L+FP + I A+DLI +LL RLG GA +K
Sbjct: 372 TPFKGMDHELTLANIV--ARALEFPKEPTIPSAAKDLISQLLAKDPSRRLGSSLGATAVK 429
Query: 671 AHPFFSGVDWNTIRQVEAPYIP 692
HPFF GV+W + P++P
Sbjct: 430 RHPFFQGVNWALLMCTRPPFLP 451
>At3g25250 [R] KOG0610 Putative serine/threonine protein kinase
Length = 421
Score = 150 bits (379), Expect = 7e-36
Identities = 112/362 (30%), Positives = 171/362 (46%), Gaps = 42/362 (11%)
Query: 346 DFNSVKVI---GKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNK--------DQLAHVKA 394
DFN ++V+ G+GA G V LV + D K+ A+K +LK + K D+ V
Sbjct: 13 DFNRLEVLSLLGRGAKGVVFLV-RDDDAKLLALKVILKEAIEKKKKGRESEDDEYKRVSF 71
Query: 395 ERDVLAGSDSPWVVSLYYSFQDSQYLYLIMEFLPGGDLMTM--LIRWQIFTEDVTRFYMA 452
E+ VL+ D P SL+ + + +++ PG +L ++ + +F++++ RFY A
Sbjct: 72 EQGVLSRFDHPLFPSLHGVLATDKVIGYAIDYCPGQNLNSLRKMQSESMFSDEIIRFYAA 131
Query: 453 ECILAIEVIHKLGFIHRDIKPDNILIDIRGHIKLSDFGLSTGF-HKTHDSSYYXXXXXXX 511
E +LA++ +H G ++RD+KPDN++I GH+ L DF LST +T S
Sbjct: 132 ELVLALDYLHNQGIVYRDLKPDNVMIQENGHLMLIDFDLSTNLAPRTPQPS---PSLSKP 188
Query: 512 XXXXXXXXXXXXXXXXXXXXXXPNETNNGNRNTMLVDAIHLTMTNRQQMQTWRKSRRLMA 571
P E+ ++H + T + KS
Sbjct: 189 SPTMKRKKRLFRFTSFCNSGISPQES----------ISVHSSSTLAVSDSSGEKSN---- 234
Query: 572 YSTVGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQ 631
S VGT +Y+APE+ G+ DWWSLG ++YE L G PF +ET+ +I++
Sbjct: 235 -SFVGTEEYVAPEVISGDGHDFAVDWWSLGVVLYEMLYGATPFRGSNRKETFYRILS--- 290
Query: 632 TLQFPDDIHISYEAEDLIRRLLTHSENRLGRHGGADEIKAHPFFSGVDWNTIRQV-EAPY 690
+ P+ + DLIRRLL E R +EIK H FF GVDW + V PY
Sbjct: 291 --KPPNLTGETTSLRDLIRRLL---EKDPSRRINVEEIKGHDFFRGVDWEKVILVSRPPY 345
Query: 691 IP 692
IP
Sbjct: 346 IP 347
>7291910 [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 755
Score = 150 bits (379), Expect = 7e-36
Identities = 115/424 (27%), Positives = 196/424 (46%), Gaps = 35/424 (8%)
Query: 290 QSSVGYAIERNQRRLELESELASQDWSEERKNRQLASLGKKESQFXXXXXXXXXXDDFNS 349
Q GY ++ Q++ + + E Q + ++ +QL + + S +DF
Sbjct: 120 QHQQGYQSQQQQQQPQQQQEQQQQQ-EQSQQQQQLQNPAPRRSP-----------NDFIF 167
Query: 350 VKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAG-SDSPWVV 408
+ IG+G++ V L + + YA+K K + + + ++K ER+V+ ++ P V
Sbjct: 168 GRYIGEGSYSIVYLAVDIHSRREYAIKVCEKRLILRERKQDYIKREREVMHQMTNVPGFV 227
Query: 409 SLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKLGFIH 468
+L +FQD + LY +M + GD++ + R F TR Y AE +LA E +H+ +H
Sbjct: 228 NLSCTFQDQRSLYFVMTYARKGDMLPYINRVGSFDVACTRHYAAELLLACEHMHRRNVVH 287
Query: 469 RDIKPDNILIDIRGHIKLSDFG---LSTGFHKTHDSSYYXXXXXXXXXXXXXXXXXXXXX 525
RD+KP+NIL+D H ++DFG + T + + +
Sbjct: 288 RDLKPENILLDEDMHTLIADFGSAKVMTAHERALATEHCSEQRRSNSDEDDEDSDRLENE 347
Query: 526 XXXXXXXXPNETNNGNRNTMLVDAIHLTMTNRQQMQTWRKSRRLMAYSTVGTPDYIAPEI 585
E ++G+ + M + + Q R+ R S VGT Y++PE+
Sbjct: 348 DEDFYDRDSEELDDGDDEQQQEE-----MDSPRHRQ--RRYNRHRKASFVGTAQYVSPEV 400
Query: 586 FLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQFPDDIHISYEA 645
D W+LG I+Y+ + G PPF +++I+ + + FP +A
Sbjct: 401 LQNGPITPAADLWALGCIVYQMIAGLPPFRGSNDYVIFKEIL--DCAVDFPQG--FDKDA 456
Query: 646 EDLIRRLL-THSENRLG---RHGGADEIKAHPFFSGVDWNTIRQVEA----PYIPKLSSV 697
EDL+R+LL +RLG G + I+AHPFF+G+DW T+RQ PY+P +S
Sbjct: 457 EDLVRKLLRVDPRDRLGAQDEFGYYESIRAHPFFAGIDWQTLRQQTPPPIYPYLPGVSQD 516
Query: 698 TDTR 701
D R
Sbjct: 517 EDFR 520
>At1g53700 [R] KOG0610 Putative serine/threonine protein kinase
Length = 476
Score = 150 bits (378), Expect = 9e-36
Identities = 109/361 (30%), Positives = 171/361 (47%), Gaps = 39/361 (10%)
Query: 347 FNSVKVIGKGAFGEVRLVQKKD----TGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGS 402
F V+ +G G G V L +D TG +A+K + + + K +++HV+ E ++L+
Sbjct: 93 FKLVRHLGTGNLGRVFLCHLRDCPNPTG--FALKVIDRDVLTAK-KISHVETEAEILSLL 149
Query: 403 DSPWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVT--RFYMAECILAIEV 460
D P++ +LY S Y L++++ P GDL ++L + ++ RF+ AE ++A+E
Sbjct: 150 DHPFLPTLYARIDASHYTCLLIDYCPNGDLHSLLRKQPNNRLPISPVRFFAAEVLVALEY 209
Query: 461 IHKLGFIHRDIKPDNILIDIRGHIKLSDFGLSTGFHKTHDSSYYXXXXXXXXXXXXXXXX 520
+H LG ++RD+KP+NILI GHI LSDF L
Sbjct: 210 LHALGIVYRDLKPENILIREDGHIMLSDFDLC---------------------FKADVVP 248
Query: 521 XXXXXXXXXXXXXPNETNNGNRNTMLVDAIHLTMTNRQQMQTWRKSRRLMAY--STVGTP 578
P +T G + + R+++ + + A+ S VGT
Sbjct: 249 TFRSRRFRRTSSSPRKTRRGG-GCFSTEVEY----EREEIVAEFAAEPVTAFSKSCVGTH 303
Query: 579 DYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQFPDD 638
+Y+APE+ G+G DWW+ G +YE L G PF T ++T R I++ + F +
Sbjct: 304 EYLAPELVAGNGHGSGVDWWAFGIFLYEMLYGTTPFKGGTKEQTLRNIVS-NDDVAFTLE 362
Query: 639 IHISYEAEDLIRRLLTHS-ENRLGRHGGADEIKAHPFFSGVDWNTIRQVEAPYIPKLSSV 697
EA+DLI +LL RLG GA +IK H FF G+ W IR + P I L
Sbjct: 363 EEGMVEAKDLIEKLLVKDPRKRLGCARGAQDIKRHEFFEGIKWPLIRNYKPPEIRGLVKK 422
Query: 698 T 698
T
Sbjct: 423 T 423
>YMR104c [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 677
Score = 147 bits (372), Expect = 5e-35
Identities = 76/158 (48%), Positives = 109/158 (68%)
Query: 345 DDFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDS 404
DDF+ +KVIGKG+FG+V V+KKDT KIYA+K L K+ + +K ++ H AER VLA D
Sbjct: 342 DDFDLLKVIGKGSFGKVMQVRKKDTQKIYALKALRKAYIVSKCEVTHTLAERTVLARVDC 401
Query: 405 PWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKL 464
P++V L +SFQ + LYL++ F+ GG+L L F+ +RFY+AE + A++ +HKL
Sbjct: 402 PFIVPLKFSFQSPEKLYLVLAFINGGELFYHLQHEGRFSLARSRFYIAELLCALDSLHKL 461
Query: 465 GFIHRDIKPDNILIDIRGHIKLSDFGLSTGFHKTHDSS 502
I+RD+KP+NIL+D +GHI L DFGL K +D +
Sbjct: 462 DVIYRDLKPENILLDYQGHIALCDFGLCKLNMKDNDKT 499
Score = 99.0 bits (245), Expect = 2e-20
Identities = 54/139 (38%), Positives = 77/139 (54%), Gaps = 6/139 (4%)
Query: 576 GTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQF 635
GTP+Y+APEI L QGY + DWW+LG ++YE + G PP+ E Y+KI+ +Q L F
Sbjct: 504 GTPEYLAPEILLGQGYTKTVDWWTLGILLYEMMTGLPPYYDENVPVMYKKIL--QQPLLF 561
Query: 636 PDDIHISYEAEDLIRRLLTHSENRLGRHGGADEIKAHPFFSGVDWN--TIRQVEAPYIPK 693
PD + A+DL+ LL+ +R G DEI+ HPFF + W ++ PY P
Sbjct: 562 PDGFDPA--AKDLLIGLLSRDPSRRLGVNGTDEIRNHPFFKDISWKKLLLKGYIPPYKPI 619
Query: 694 LSSVTDTRFFPTDELENVP 712
+ S DT F + + P
Sbjct: 620 VKSEIDTANFDQEFTKEKP 638
>Hs7657526 [T] KOG0603 Ribosomal protein S6 kinase
Length = 745
Score = 147 bits (372), Expect = 5e-35
Identities = 73/149 (48%), Positives = 110/149 (72%), Gaps = 4/149 (2%)
Query: 347 FNSVKVIGKGAFGEVRLVQKK---DTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSD 403
F +KV+G+G+FG+V LV+KK D G++YAMK L K+ + +D++ K ERD+L +
Sbjct: 73 FELLKVLGQGSFGKVFLVRKKTGPDAGQLYAMKVLKKASLKVRDRV-RTKMERDILVEVN 131
Query: 404 SPWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHK 463
P++V L+Y+FQ LYLI++FL GGD+ T L + +FTE+ +FY+AE LA++ +H+
Sbjct: 132 HPFIVKLHYAFQTEGKLYLILDFLRGGDVFTRLSKEVLFTEEDVKFYLAELALALDHLHQ 191
Query: 464 LGFIHRDIKPDNILIDIRGHIKLSDFGLS 492
LG ++RD+KP+NIL+D GHIKL+DFGLS
Sbjct: 192 LGIVYRDLKPENILLDEIGHIKLTDFGLS 220
Score = 92.0 bits (227), Expect = 3e-18
Identities = 57/149 (38%), Positives = 80/149 (53%), Gaps = 9/149 (6%)
Query: 571 AYSTVGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFE 630
AYS GT +Y+APE+ +G+ Q DWWS G +M+E L G PF + ET I+ +
Sbjct: 230 AYSFCGTVEYMAPEVVNRRGHSQSADWWSYGVLMFEMLTGTLPFQGKDRNETMNMIL--K 287
Query: 631 QTLQFPDDIHISYEAEDLIRRLLTHS-ENRLGRHGGADEIKAHPFFSGVDWNTI--RQVE 687
L P +S EA+ L+R L + NRLG G +EIK H FF+ +DW+ + R+V+
Sbjct: 288 AKLGMPQ--FLSAEAQSLLRMLFKRNPANRLGSE-GVEEIKRHLFFANIDWDKLYKREVQ 344
Query: 688 APYIPKLSSVTDTRFFPTDELENVP-DSP 715
P+ P DT F + P DSP
Sbjct: 345 PPFKPASGKPDDTFCFDPEFTAKTPKDSP 373
Score = 58.9 bits (141), Expect = 3e-08
Identities = 30/80 (37%), Positives = 48/80 (59%), Gaps = 3/80 (3%)
Query: 577 TPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFC---SETPQETYRKIMNFEQTL 633
T +++APE+ + QGY CD WSLG + Y L G+ PF ++TP+E +I N + +L
Sbjct: 585 TANFVAPEVLMQQGYDAACDIWSLGVLFYTMLAGYTPFANGPNDTPEEILLRIGNGKFSL 644
Query: 634 QFPDDIHISYEAEDLIRRLL 653
+ +IS A+DL+ +L
Sbjct: 645 SGGNWDNISDGAKDLLSHML 664
Score = 57.0 bits (136), Expect = 1e-07
Identities = 34/144 (23%), Positives = 70/144 (48%), Gaps = 10/144 (6%)
Query: 353 IGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDSPWVVSLYY 412
IG G++ + T +A+K + KS+ +++ ++ P +++L
Sbjct: 432 IGVGSYSVCKRCIHATTNMEFAVKIIDKSKRDPSEEI------EILMRYGQHPNIITLKD 485
Query: 413 SFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKLGFIHRDIK 472
F D +Y+YL+ + + GG+L+ +++ + F+E + ++ +H G +HRD+K
Sbjct: 486 VFDDGRYVYLVTDLMKGGELLDRILKQKCFSEREASDILYVISKTVDYLHCQGVVHRDLK 545
Query: 473 PDNILI----DIRGHIKLSDFGLS 492
P NIL I++ DFG +
Sbjct: 546 PSNILYMDESASADSIRICDFGFA 569
>CE18169 [T] KOG0603 Ribosomal protein S6 kinase
Length = 797
Score = 147 bits (372), Expect = 5e-35
Identities = 74/149 (49%), Positives = 108/149 (71%), Gaps = 4/149 (2%)
Query: 347 FNSVKVIGKGAFGEVRLVQK---KDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSD 403
F +KV+G+G+FG+V LV+K +D+G +YAMK L K+ + +D+ K ER++LA
Sbjct: 104 FELLKVLGQGSFGKVFLVRKVRGRDSGHVYAMKVLKKATLKVRDR-QRTKLERNILAHIS 162
Query: 404 SPWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHK 463
P++V L+Y+FQ LYLI++FL GGDL T L + +FTED +FY+AE LA+E +H
Sbjct: 163 HPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEDDVKFYLAELTLALEHLHS 222
Query: 464 LGFIHRDIKPDNILIDIRGHIKLSDFGLS 492
LG ++RD+KP+NIL+D GHIK++DFGLS
Sbjct: 223 LGIVYRDLKPENILLDADGHIKVTDFGLS 251
Score = 87.4 bits (215), Expect = 7e-17
Identities = 51/149 (34%), Positives = 85/149 (56%), Gaps = 9/149 (6%)
Query: 572 YSTVGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQ 631
YS GT +Y+APE+ +G+ D+WSLG +M+E L G PF +T +I+ +
Sbjct: 262 YSFCGTVEYMAPEVINRRGHSMAADFWSLGVLMFEMLTGHLPFQGRDRNDTMTQILKAKL 321
Query: 632 TLQFPDDIHISYEAEDLIRRLL-THSENRLGR-HGGADEIKAHPFFSGVDWNTI--RQVE 687
++ ++ EA+ L+R L +S+NRLG G +EIK H FF+ +D+ + ++++
Sbjct: 322 SMPH----FLTQEAQSLLRALFKRNSQNRLGAGPDGVEEIKRHAFFAKIDFVKLLNKEID 377
Query: 688 APYIPKLSSVTDTRFFPTDELENVP-DSP 715
P+ P LS+V T +F + + P DSP
Sbjct: 378 PPFKPALSTVDSTSYFDPEFTKRTPKDSP 406
Score = 61.2 bits (147), Expect = 6e-09
Identities = 41/153 (26%), Positives = 77/153 (49%), Gaps = 11/153 (7%)
Query: 345 DDFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDS 404
DD+ ++ IG GA V Q K T + YA+K ++K +++ + + +L S
Sbjct: 452 DDYEILEKIGNGAHSVVHKCQMKATRRKYAVK-IVKKAVFDATEEVDI-----LLRHSHH 505
Query: 405 PWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLI-RWQIFTEDVTRFYMAECILAIEVIHK 463
+VV L+ ++D +Y+I E GG+L+ L+ + + +E MA + A++ +H
Sbjct: 506 QFVVKLFDVYEDETAIYMIEELCEGGELLDKLVNKKSLGSEKEVAAIMANLLNAVQYLHS 565
Query: 464 LGFIHRDIKPDNILIDIR----GHIKLSDFGLS 492
HRD+ NIL ++ +++ DFG +
Sbjct: 566 QQVAHRDLTAANILFALKDGDPSSLRIVDFGFA 598
Score = 60.8 bits (146), Expect = 7e-09
Identities = 30/86 (34%), Positives = 51/86 (58%), Gaps = 3/86 (3%)
Query: 577 TPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFC---SETPQETYRKIMNFEQTL 633
T ++APE+ QGY + CD WSLG +++ L G PF ++TP + +++ + + ++
Sbjct: 614 TAQFVAPEVLRKQGYDRSCDVWSLGVLLHTMLTGCTPFAMGPNDTPDQILQRVGDGKISM 673
Query: 634 QFPDDIHISYEAEDLIRRLLTHSENR 659
P IS EA+DL+R++L NR
Sbjct: 674 THPVWDTISDEAKDLVRKMLDVDPNR 699
>CE13014 [T] KOG0603 Ribosomal protein S6 kinase
Length = 740
Score = 147 bits (372), Expect = 5e-35
Identities = 74/149 (49%), Positives = 108/149 (71%), Gaps = 4/149 (2%)
Query: 347 FNSVKVIGKGAFGEVRLVQK---KDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSD 403
F +KV+G+G+FG+V LV+K +D+G +YAMK L K+ + +D+ K ER++LA
Sbjct: 47 FELLKVLGQGSFGKVFLVRKVRGRDSGHVYAMKVLKKATLKVRDR-QRTKLERNILAHIS 105
Query: 404 SPWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHK 463
P++V L+Y+FQ LYLI++FL GGDL T L + +FTED +FY+AE LA+E +H
Sbjct: 106 HPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEDDVKFYLAELTLALEHLHS 165
Query: 464 LGFIHRDIKPDNILIDIRGHIKLSDFGLS 492
LG ++RD+KP+NIL+D GHIK++DFGLS
Sbjct: 166 LGIVYRDLKPENILLDADGHIKVTDFGLS 194
Score = 87.4 bits (215), Expect = 7e-17
Identities = 51/149 (34%), Positives = 85/149 (56%), Gaps = 9/149 (6%)
Query: 572 YSTVGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQ 631
YS GT +Y+APE+ +G+ D+WSLG +M+E L G PF +T +I+ +
Sbjct: 205 YSFCGTVEYMAPEVINRRGHSMAADFWSLGVLMFEMLTGHLPFQGRDRNDTMTQILKAKL 264
Query: 632 TLQFPDDIHISYEAEDLIRRLL-THSENRLGR-HGGADEIKAHPFFSGVDWNTI--RQVE 687
++ ++ EA+ L+R L +S+NRLG G +EIK H FF+ +D+ + ++++
Sbjct: 265 SMPH----FLTQEAQSLLRALFKRNSQNRLGAGPDGVEEIKRHAFFAKIDFVKLLNKEID 320
Query: 688 APYIPKLSSVTDTRFFPTDELENVP-DSP 715
P+ P LS+V T +F + + P DSP
Sbjct: 321 PPFKPALSTVDSTSYFDPEFTKRTPKDSP 349
Score = 61.2 bits (147), Expect = 6e-09
Identities = 41/153 (26%), Positives = 77/153 (49%), Gaps = 11/153 (7%)
Query: 345 DDFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDS 404
DD+ ++ IG GA V Q K T + YA+K ++K +++ + + +L S
Sbjct: 395 DDYEILEKIGNGAHSVVHKCQMKATRRKYAVK-IVKKAVFDATEEVDI-----LLRHSHH 448
Query: 405 PWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLI-RWQIFTEDVTRFYMAECILAIEVIHK 463
+VV L+ ++D +Y+I E GG+L+ L+ + + +E MA + A++ +H
Sbjct: 449 QFVVKLFDVYEDETAIYMIEELCEGGELLDKLVNKKSLGSEKEVAAIMANLLNAVQYLHS 508
Query: 464 LGFIHRDIKPDNILIDIR----GHIKLSDFGLS 492
HRD+ NIL ++ +++ DFG +
Sbjct: 509 QQVAHRDLTAANILFALKDGDPSSLRIVDFGFA 541
Score = 60.8 bits (146), Expect = 7e-09
Identities = 30/86 (34%), Positives = 51/86 (58%), Gaps = 3/86 (3%)
Query: 577 TPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFC---SETPQETYRKIMNFEQTL 633
T ++APE+ QGY + CD WSLG +++ L G PF ++TP + +++ + + ++
Sbjct: 557 TAQFVAPEVLRKQGYDRSCDVWSLGVLLHTMLTGCTPFAMGPNDTPDQILQRVGDGKISM 616
Query: 634 QFPDDIHISYEAEDLIRRLLTHSENR 659
P IS EA+DL+R++L NR
Sbjct: 617 THPVWDTISDEAKDLVRKMLDVDPNR 642
>Hs4759050 [T] KOG0603 Ribosomal protein S6 kinase
Length = 740
Score = 147 bits (371), Expect = 6e-35
Identities = 83/203 (40%), Positives = 122/203 (59%), Gaps = 7/203 (3%)
Query: 296 AIERNQRRLELESELASQDWSEERKNRQLASLGKKESQFXXXXXXXXXXDD---FNSVKV 352
A+E E ++ + EE N Q + KE D F +KV
Sbjct: 14 AVESPSDSAENGQQIMDEPMGEEEINPQTEEVSIKEIAITHHVKEGHEKADPSQFELLKV 73
Query: 353 IGKGAFGEVRLVQK---KDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDSPWVVS 409
+G+G+FG+V LV+K D ++YAMK L K+ + +D++ K ERD+L + P++V
Sbjct: 74 LGQGSFGKVFLVKKISGSDARQLYAMKVLKKATLKVRDRV-RTKMERDILVEVNHPFIVK 132
Query: 410 LYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKLGFIHR 469
L+Y+FQ LYLI++FL GGDL T L + +FTE+ +FY+AE LA++ +H LG I+R
Sbjct: 133 LHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLHSLGIIYR 192
Query: 470 DIKPDNILIDIRGHIKLSDFGLS 492
D+KP+NIL+D GHIKL+DFGLS
Sbjct: 193 DLKPENILLDEEGHIKLTDFGLS 215
Score = 94.0 bits (232), Expect = 8e-19
Identities = 58/150 (38%), Positives = 81/150 (53%), Gaps = 9/150 (6%)
Query: 571 AYSTVGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFE 630
AYS GT +Y+APE+ +G+ Q DWWS G +M+E L G PF + +ET I+ +
Sbjct: 225 AYSFCGTVEYMAPEVVNRRGHTQSADWWSFGVLMFEMLTGTLPFQGKDRKETMTMIL--K 282
Query: 631 QTLQFPDDIHISYEAEDLIRRLLTHS-ENRLGR-HGGADEIKAHPFFSGVDWNTI--RQV 686
L P +S EA+ L+R L + NRLG G +EIK H FFS +DWN + R++
Sbjct: 283 AKLGMPQ--FLSPEAQSLLRMLFKRNPANRLGAGPDGVEEIKRHSFFSTIDWNKLYRREI 340
Query: 687 EAPYIPKLSSVTDTRFFPTDELENVP-DSP 715
P+ P DT +F + P DSP
Sbjct: 341 HPPFKPATGRPEDTFYFDPEFTAKTPKDSP 370
Score = 67.4 bits (163), Expect = 8e-11
Identities = 41/152 (26%), Positives = 79/152 (51%), Gaps = 10/152 (6%)
Query: 345 DDFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDS 404
D + + IG G++ + K T +A+K + KS+ +D ++ +L
Sbjct: 420 DGYEVKEDIGVGSYSVCKRCIHKATNMEFAVKIIDKSK---RDPTEEIEI---LLRYGQH 473
Query: 405 PWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKL 464
P +++L + D +Y+Y++ E + GG+L+ ++R + F+E + +E +H
Sbjct: 474 PNIITLKDVYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEYLHAQ 533
Query: 465 GFIHRDIKPDNIL-IDIRGH---IKLSDFGLS 492
G +HRD+KP NIL +D G+ I++ DFG +
Sbjct: 534 GVVHRDLKPSNILYVDESGNPESIRICDFGFA 565
Score = 55.8 bits (133), Expect = 2e-07
Identities = 39/126 (30%), Positives = 65/126 (50%), Gaps = 15/126 (11%)
Query: 577 TPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCS---ETPQETYRKIMNFEQTL 633
T +++APE+ QGY CD WSLG ++Y L G+ PF + +TP+E +I + + +L
Sbjct: 581 TANFVAPEVLKRQGYDAACDIWSLGVLLYTMLTGYTPFANGPDDTPEEILARIGSGKFSL 640
Query: 634 QFPDDIHISYEAEDLIRRLL-THSENRLGRHGGADEIKAHPFFSGVDWNTIRQV-----E 687
+S A+DL+ ++L RL A + HP+ V W+ + Q +
Sbjct: 641 SGGYWNSVSDTAKDLVSKMLHVDPHQRL----TAALVLRHPWI--VHWDQLPQYQLNRQD 694
Query: 688 APYIPK 693
AP++ K
Sbjct: 695 APHLVK 700
>Hs20149547 [T] KOG0603 Ribosomal protein S6 kinase
Length = 735
Score = 147 bits (371), Expect = 6e-35
Identities = 75/149 (50%), Positives = 108/149 (72%), Gaps = 4/149 (2%)
Query: 347 FNSVKVIGKGAFGEVRLVQK---KDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSD 403
F +KV+G+G+FG+V LV+K D+G +YAMK L K+ + +D++ K ERD+LA +
Sbjct: 62 FELLKVLGQGSFGKVFLVRKVTRPDSGHLYAMKVLKKATLKVRDRV-RTKMERDILADVN 120
Query: 404 SPWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHK 463
P+VV L+Y+FQ LYLI++FL GGDL T L + +FTE+ +FY+AE L ++ +H
Sbjct: 121 HPFVVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALGLDHLHS 180
Query: 464 LGFIHRDIKPDNILIDIRGHIKLSDFGLS 492
LG I+RD+KP+NIL+D GHIKL+DFGLS
Sbjct: 181 LGIIYRDLKPENILLDEEGHIKLTDFGLS 209
Score = 98.2 bits (243), Expect = 4e-20
Identities = 59/150 (39%), Positives = 85/150 (56%), Gaps = 9/150 (6%)
Query: 571 AYSTVGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFE 630
AYS GT +Y+APE+ QG+ DWWS G +M+E L G PF + +ET I+ +
Sbjct: 219 AYSFCGTVEYMAPEVVNRQGHSHSADWWSYGVLMFEMLTGSLPFQGKDRKETMTLIL--K 276
Query: 631 QTLQFPDDIHISYEAEDLIRRLLTHS-ENRLGR-HGGADEIKAHPFFSGVDWNTI--RQV 686
L P +S EA+ L+R L + NRLG GA+EIK H F+S +DWN + R++
Sbjct: 277 AKLGMPQ--FLSTEAQSLLRALFKRNPANRLGSGPDGAEEIKRHVFYSTIDWNKLYRREI 334
Query: 687 EAPYIPKLSSVTDTRFFPTDELENVP-DSP 715
+ P+ P ++ DT +F T+ P DSP
Sbjct: 335 KPPFKPAVAQPDDTFYFDTEFTSRTPKDSP 364
Score = 72.8 bits (177), Expect = 2e-12
Identities = 42/152 (27%), Positives = 80/152 (52%), Gaps = 10/152 (6%)
Query: 345 DDFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDS 404
D + + IG G++ E + K T YA+K + KS+ +++ +L
Sbjct: 416 DGYVVKETIGVGSYSECKRCVHKATNMEYAVKVIDKSKRDPSEEI------EILLRYGQH 469
Query: 405 PWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKL 464
P +++L + D +++YL+ E + GG+L+ ++R + F+E F + +E +H
Sbjct: 470 PNIITLKDVYDDGKHVYLVTELMRGGELLDKILRQKFFSEREASFVLHTIGKTVEYLHSQ 529
Query: 465 GFIHRDIKPDNIL-IDIRGH---IKLSDFGLS 492
G +HRD+KP NIL +D G+ +++ DFG +
Sbjct: 530 GVVHRDLKPSNILYVDESGNPECLRICDFGFA 561
Score = 60.1 bits (144), Expect = 1e-08
Identities = 36/107 (33%), Positives = 59/107 (54%), Gaps = 8/107 (7%)
Query: 577 TPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFC---SETPQETYRKIMNFEQTL 633
T +++APE+ QGY + CD WSLG ++Y L G+ PF S+TP+E +I + + TL
Sbjct: 577 TANFVAPEVLKRQGYDEGCDIWSLGILLYTMLAGYTPFANGPSDTPEEILTRIGSGKFTL 636
Query: 634 QFPDDIHISYEAEDLIRRLL-THSENRLGRHGGADEIKAHPFFSGVD 679
+ +S A+DL+ ++L RL A ++ HP+ + D
Sbjct: 637 SGGNWNTVSETAKDLVSKMLHVDPHQRL----TAKQVLQHPWVTQKD 679
>SPCC1450.11c [R] KOG0605 NDR and related serine/threonine kinases
Length = 1338
Score = 147 bits (370), Expect = 8e-35
Identities = 76/157 (48%), Positives = 104/157 (65%), Gaps = 2/157 (1%)
Query: 345 DDFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGS-D 403
+D+ +K I KGAFG V L QK+ TG +A+K L KS M K+Q+ +V+AER +L +
Sbjct: 587 NDYKILKPISKGAFGSVYLAQKRTTGDYFAIKILKKSNMIAKNQVINVRAERAILMSQGE 646
Query: 404 SPWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHK 463
SP+V LYY+FQ YLYL+ME+L GGD ++L + D R Y+AE +L + +H
Sbjct: 647 SPFVAKLYYTFQSKDYLYLVMEYLNGGDCGSLLKTMGVLDLDWIRTYIAETVLCLGDLHD 706
Query: 464 LGFIHRDIKPDNILIDIRGHIKLSDFGLS-TGFHKTH 499
G IHRDIKP+N+LI GH+KL+DFGLS G+ K H
Sbjct: 707 RGIIHRDIKPENLLISQNGHLKLTDFGLSRVGYMKRH 743
Score = 113 bits (283), Expect = 1e-24
Identities = 71/203 (34%), Positives = 104/203 (50%), Gaps = 20/203 (9%)
Query: 575 VGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQ 634
+GTPDYIAPE+ L + DWWSLG +++E L G+PPF +ETP + ++ I+ + +
Sbjct: 858 IGTPDYIAPEVILGNPGIKASDWWSLGCVVFEFLFGYPPFNAETPDQVFQNIL--ARRIN 915
Query: 635 FPDDIHI--SYEAEDLIRRLL-THSENRLGRHGGADEIKAHPFFSGVDWNTIRQVEAPYI 691
+P ++ S A DLI RLL + NRLG + G +EIKAHPFF V+W+TI + + P++
Sbjct: 916 WPAEVFTAESSVALDLIDRLLCMNPANRLGAN-GVEEIKAHPFFKSVNWDTILEEDPPFV 974
Query: 692 PKLSSVTDTRFFPTDELENVPDSPXX---XXXXXXXXXXXXXXXGVPQ-----------S 737
PK S DT +F + L+ S +PQ S
Sbjct: 975 PKPFSPEDTVYFDSRGLKGFDFSEYYNQPTVTEAQKLEEERPASSIPQHVSGNRKGRLRS 1034
Query: 738 NAKEDLPFIGYTYSRFDYLTRKN 760
N F +TY D+L + N
Sbjct: 1035 NTISTPEFGSFTYRNLDFLNKAN 1057
>Hs14249562 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 878
Score = 147 bits (370), Expect = 8e-35
Identities = 74/148 (50%), Positives = 107/148 (72%), Gaps = 2/148 (1%)
Query: 345 DDFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDS 404
++F+ VK I +GAFG+V L QK GK+YA+K + K++M NK+ V+AERD LA S S
Sbjct: 33 EEFSIVKPISRGAFGKVYLGQKG--GKLYAVKVVKKADMINKNMTHQVQAERDALALSKS 90
Query: 405 PWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKL 464
P++V LYYS Q + +YL+ME+L GGD+ ++L + F E++ Y++E LA++ +H+
Sbjct: 91 PFIVHLYYSLQSANNVYLVMEYLIGGDVKSLLHIYGYFDEEMAVKYISEVALALDYLHRH 150
Query: 465 GFIHRDIKPDNILIDIRGHIKLSDFGLS 492
G IHRD+KPDN+LI GHIKL+DFGLS
Sbjct: 151 GIIHRDLKPDNMLISNEGHIKLTDFGLS 178
Score = 104 bits (259), Expect = 6e-22
Identities = 50/132 (37%), Positives = 79/132 (58%), Gaps = 6/132 (4%)
Query: 575 VGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQ 634
+GTPDY+APE+ L + +G DWW+LG ++E L G PPF ETPQ+ ++ I+ ++ +
Sbjct: 738 LGTPDYLAPELLLGRAHGPAVDWWALGVCLFEFLTGIPPFNDETPQQVFQNIL--KRDIP 795
Query: 635 FPD-DIHISYEAEDLIRRLLTHSENRLGRHGGADEIKAHPFFSGVDWNTIRQVEAPYIPK 693
+P+ + +S A+ + LLT + + G E+K HP FS VDW ++ P+IP+
Sbjct: 796 WPEGEEKLSDNAQSAVEILLTIDDT---KRAGMKELKRHPLFSDVDWENLQHQTMPFIPQ 852
Query: 694 LSSVTDTRFFPT 705
TDT +F T
Sbjct: 853 PDDETDTSYFET 864
>7294265 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 2139
Score = 146 bits (369), Expect = 1e-34
Identities = 71/148 (47%), Positives = 105/148 (69%)
Query: 345 DDFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDS 404
+DF+ VK+I GA+G V LV+ K T + +AMK + K+ + ++Q+ V AERD+L+ +D+
Sbjct: 833 NDFDIVKLISNGAYGAVYLVKHKTTRQRFAMKKINKNNLILRNQVEQVFAERDILSFADN 892
Query: 405 PWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKL 464
P+VVS+Y SF+ ++L L+ME++ GGD T+L D+ RFY AE +LA+E +H
Sbjct: 893 PFVVSMYCSFETKKHLCLVMEYVEGGDCGTLLKNIGPLPADMARFYFAETVLAVEYLHSY 952
Query: 465 GFIHRDIKPDNILIDIRGHIKLSDFGLS 492
G +HRD+KPDN+LI GHIKL+DFGLS
Sbjct: 953 GIVHRDLKPDNLLITALGHIKLTDFGLS 980
Score = 122 bits (305), Expect = 3e-27
Identities = 61/144 (42%), Positives = 92/144 (63%), Gaps = 5/144 (3%)
Query: 565 KSRRLMAYSTVGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYR 624
++R+ GTP+YIAPE+ L QGYG+ DWWS+G I+YE LIG PF ET +E +
Sbjct: 999 ETRQFSDKQVYGTPEYIAPEVILRQGYGKPVDWWSMGIILYEFLIGCVPFFGETTEELFA 1058
Query: 625 KIMNFEQTLQFPD--DIHISYEAEDLIRRLLTHS-ENRLGRHGGADEIKAHPFFSGVDWN 681
+N +++PD D + EA+D+I +LL + +RLG GA E+K H +F G+DWN
Sbjct: 1059 HTVN--DDIEWPDSEDWPVQAEAKDIISQLLQQNPRDRLGTQSGALEMKEHEYFLGMDWN 1116
Query: 682 TIRQVEAPYIPKLSSVTDTRFFPT 705
++ + +A ++P+LS DT +F T
Sbjct: 1117 SLLRQKAEFVPQLSHDDDTSYFDT 1140
>Hs19923570 [T] KOG0603 Ribosomal protein S6 kinase
Length = 733
Score = 146 bits (368), Expect = 1e-34
Identities = 73/149 (48%), Positives = 109/149 (72%), Gaps = 4/149 (2%)
Query: 347 FNSVKVIGKGAFGEVRLVQK---KDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSD 403
F +KV+G+G++G+V LV+K D G++YAMK L K+ + +D++ K ERD+LA +
Sbjct: 59 FELLKVLGQGSYGKVFLVRKVKGSDAGQLYAMKVLKKATLKVRDRVRS-KMERDILAEVN 117
Query: 404 SPWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHK 463
P++V L+Y+FQ LYLI++FL GGDL T L + +FTE+ +FY+AE LA++ +H
Sbjct: 118 HPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLHS 177
Query: 464 LGFIHRDIKPDNILIDIRGHIKLSDFGLS 492
LG I+RD+KP+NIL+D GHIK++DFGLS
Sbjct: 178 LGIIYRDLKPENILLDEEGHIKITDFGLS 206
Score = 94.4 bits (233), Expect = 6e-19
Identities = 58/150 (38%), Positives = 83/150 (54%), Gaps = 9/150 (6%)
Query: 571 AYSTVGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFE 630
AYS GT +Y+APE+ +G+ Q DWWS G +M+E L G PF + +ET I+ +
Sbjct: 216 AYSFCGTIEYMAPEVVNRRGHTQSADWWSFGVLMFEMLTGSLPFQGKDRKETMALIL--K 273
Query: 631 QTLQFPDDIHISYEAEDLIRRLLTHSE-NRLGRH-GGADEIKAHPFFSGVDWNTI--RQV 686
L P +S EA+ L+R L + NRLG G +EIK HPFF +DWNT+ +++
Sbjct: 274 AKLGMPQ--FLSGEAQSLLRALFKRNPCNRLGAGIDGVEEIKRHPFFVTIDWNTLYRKEI 331
Query: 687 EAPYIPKLSSVTDTRFFPTDELENVP-DSP 715
+ P+ P + DT F + P DSP
Sbjct: 332 KPPFKPAVGRPEDTFHFDPEFTARTPTDSP 361
Score = 66.2 bits (160), Expect = 2e-10
Identities = 41/152 (26%), Positives = 77/152 (49%), Gaps = 10/152 (6%)
Query: 345 DDFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDS 404
D + + IG G++ + K T YA+K + KS+ +++ +L
Sbjct: 413 DGYEIKEDIGVGSYSVCKRCVHKATDTEYAVKIIDKSKRDPSEEI------EILLRYGQH 466
Query: 405 PWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKL 464
P +++L + D +++YL+ME + GG+L+ ++R + F+E + ++ +H
Sbjct: 467 PNIITLKDVYDDGKFVYLVMELMRGGELLDRILRQRYFSEREASDVLCTITKTMDYLHSQ 526
Query: 465 GFIHRDIKPDNILI-DIRG---HIKLSDFGLS 492
G +HRD+KP NIL D G I++ DFG +
Sbjct: 527 GVVHRDLKPSNILYRDESGSPESIRVCDFGFA 558
Score = 55.5 bits (132), Expect = 3e-07
Identities = 28/80 (35%), Positives = 47/80 (58%), Gaps = 3/80 (3%)
Query: 577 TPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCS---ETPQETYRKIMNFEQTL 633
T +++APE+ QGY CD WSLG ++Y L G+ PF + +TP+E +I + + L
Sbjct: 574 TANFVAPEVLKRQGYDAACDIWSLGILLYTMLAGFTPFANGPDDTPEEILARIGSGKYAL 633
Query: 634 QFPDDIHISYEAEDLIRRLL 653
+ IS A+D++ ++L
Sbjct: 634 SGGNWDSISDAAKDVVSKML 653
>At4g13000 [R] KOG0610 Putative serine/threonine protein kinase
Length = 372
Score = 146 bits (368), Expect = 1e-34
Identities = 100/355 (28%), Positives = 168/355 (47%), Gaps = 39/355 (10%)
Query: 345 DDFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNK---DQLAHVKAERDVLAG 401
D +G+G+ G V LV K K A+K +L+ + +K D+ + E+ VL+
Sbjct: 18 DHLEIFSALGRGSKGVVFLV--KADNKWLALKVILRESIESKKAKDEYKRISFEQGVLSR 75
Query: 402 SDSPWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRW--QIFTEDVTRFYMAECILAIE 459
D P L+ + + +++ PG DL ++ + ++F++++ RFY AE ++A+E
Sbjct: 76 FDHPLFPRLHGVISTDKVIGYAIDYCPGRDLNSLRKKQSEEMFSDEIIRFYAAELVIALE 135
Query: 460 VIHKLGFIHRDIKPDNILIDIRGHIKLSDFGLSTGF-HKTHDSSYYXXXXXXXXXXXXXX 518
+H G ++RD+KPDN++I GH+ L DF LST +T SS+
Sbjct: 136 YLHNQGIVYRDLKPDNVMIQENGHLMLVDFDLSTNLPPRTPQSSFSSSPRLSTATKKERS 195
Query: 519 XXXXXXXXXXXXXXXPNETNNGNRNTMLVDAIHLTMTNRQQMQTWRKSRRLMAYSTVGTP 578
+G N+ + ++ ++ + + + S VGT
Sbjct: 196 IFAF----------------SGLCNSGISPDDSVSRSSESEFSGEKSN------SFVGTE 233
Query: 579 DYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQFPDD 638
+Y+APE+ G+ DWWSLG ++YE L G PF +ET+ KI+ + P
Sbjct: 234 EYVAPEVITGSGHDFAVDWWSLGVVLYEMLYGATPFRGSNRKETFLKILT-----EPPSL 288
Query: 639 IHISYEAEDLIRRLLTHSENRLGRHGGADEIKAHPFFSGVDWNTIRQV-EAPYIP 692
+ + DL+R+LL E R + IK H FF G+DW+ + +V PYIP
Sbjct: 289 VGETTSLRDLVRKLL---EKDPSRRINVEGIKGHDFFKGLDWDLVLKVSRPPYIP 340
>7300437 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 866
Score = 146 bits (368), Expect = 1e-34
Identities = 71/148 (47%), Positives = 105/148 (69%), Gaps = 1/148 (0%)
Query: 346 DFNSVKVIGKGAFGEVRLVQKK-DTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDS 404
DF +K I +GAFG+V L K D+ +++A+K + KSEM NK+ ++ V ER+ LA S S
Sbjct: 56 DFVIIKPISRGAFGKVFLGYKNNDSKRLFAIKVMRKSEMINKNMVSQVITERNALALSRS 115
Query: 405 PWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKL 464
+ VSL+YS Q Y+YL+ME++ GGDL ++L + F E RFY+AE ++A++ +H+
Sbjct: 116 QFCVSLFYSLQSLSYVYLVMEYMVGGDLKSLLAMFGYFDEPTARFYVAEMVMALQYLHQH 175
Query: 465 GFIHRDIKPDNILIDIRGHIKLSDFGLS 492
G +HRDIKPDN+L+ GH+KL+DFGLS
Sbjct: 176 GIVHRDIKPDNMLLSSSGHVKLTDFGLS 203
Score = 103 bits (256), Expect = 1e-21
Identities = 52/141 (36%), Positives = 80/141 (55%), Gaps = 6/141 (4%)
Query: 564 RKSRRLMAYSTVGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETY 623
R+ R+ +GTPDY+APE+ L QG+G DWW+LG YE + G PPF ETPQ+ +
Sbjct: 713 RRGARVSNERILGTPDYLAPELLLKQGHGPAVDWWALGVCFYEFMTGIPPFNDETPQKVF 772
Query: 624 RKIMNFEQTLQFPD-DIHISYEAEDLIRRLLTHSENRLGRHGGADEIKAHPFFSGVDWNT 682
I+N + +++P+ D +S E+ + + LLT N A E++ F+ +DW
Sbjct: 773 DNILN--KNIEWPEGDEALSVESMEAVELLLTMDPN---ERPAAKEVQQMRHFACIDWEN 827
Query: 683 IRQVEAPYIPKLSSVTDTRFF 703
I E P++P + TDT +F
Sbjct: 828 IGNTEPPFVPTPDNPTDTGYF 848
>YKL126w [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 680
Score = 145 bits (367), Expect = 2e-34
Identities = 71/147 (48%), Positives = 102/147 (69%)
Query: 345 DDFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDS 404
DDF+ +KVIGKG+FG+V V+KKDT K+YA+K + KS + +K ++ H AER VLA D
Sbjct: 345 DDFDLLKVIGKGSFGKVMQVRKKDTQKVYALKAIRKSYIVSKSEVTHTLAERTVLARVDC 404
Query: 405 PWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKL 464
P++V L +SFQ + LY ++ F+ GG+L L + F RFY AE + A++ +HKL
Sbjct: 405 PFIVPLKFSFQSPEKLYFVLAFINGGELFYHLQKEGRFDLSRARFYTAELLCALDNLHKL 464
Query: 465 GFIHRDIKPDNILIDIRGHIKLSDFGL 491
++RD+KP+NIL+D +GHI L DFGL
Sbjct: 465 DVVYRDLKPENILLDYQGHIALCDFGL 491
Score = 101 bits (252), Expect = 4e-21
Identities = 54/139 (38%), Positives = 79/139 (55%), Gaps = 6/139 (4%)
Query: 576 GTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQF 635
GTP+Y+APE+ L GY + DWW+LG ++YE L G PP+ E + Y+KI+ ++ L F
Sbjct: 507 GTPEYLAPELLLGLGYTKAVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKIL--QEPLVF 564
Query: 636 PDDIHISYEAEDLIRRLLTHSENRLGRHGGADEIKAHPFFSGVDWNTI--RQVEAPYIPK 693
PD +A+DL+ LL+ R + GADEI+ HPFFS + W + + PY P
Sbjct: 565 PDG--FDRDAKDLLIGLLSRDPTRRLGYNGADEIRNHPFFSQLSWKRLLMKGYIPPYKPA 622
Query: 694 LSSVTDTRFFPTDELENVP 712
+S+ DT F + P
Sbjct: 623 VSNSMDTSNFDEEFTREKP 641
>YDR466w [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 898
Score = 145 bits (365), Expect = 3e-34
Identities = 97/345 (28%), Positives = 164/345 (47%), Gaps = 64/345 (18%)
Query: 346 DFNSVKVIGKGAFGEV-RLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERD---VLAG 401
DF + +G G++ V + + KK KIYA+K K + + ++ +V E++ +LA
Sbjct: 10 DFIFKEELGHGSYSTVFKALDKKSPNKIYAIKVCSKKHIIKEAKVKYVTIEKNTMNLLAQ 69
Query: 402 SDSPWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVI 461
++ LYY+F D + LY +++F PGG+L+++L + F + TR + A+ I A+E I
Sbjct: 70 KHHAGIIKLYYTFHDEENLYFVLDFAPGGELLSLLHKMGTFNDIWTRHFTAQLIDALEFI 129
Query: 462 HKLGFIHRDIKPDNILIDIRGHIKLSDFGLSTGFHKTHDSSYYXXXXXXXXXXXXXXXXX 521
H G IHRD+KP+N+L+D G + ++DFG + T D S
Sbjct: 130 HSHGIIHRDLKPENVLLDRDGRLMITDFGAAA----TIDPSLSGDSAKF----------- 174
Query: 522 XXXXXXXXXXXXPNETNNGNRNTMLVDAIHLTMTNRQQMQTWRKSRRLMAYSTVGTPDYI 581
N +NG+++ S VGT +Y+
Sbjct: 175 -------------NSDSNGSKDNQ------------------------NCASFVGTAEYV 197
Query: 582 APEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQFPDDIH- 640
+PE+ LY G D W+LG ++Y+ + G PPF E +T+ KI+ + + I+
Sbjct: 198 SPELLLYNQCGYGSDIWALGCMIYQFVQGQPPFRGENELKTFEKIVALDYPWGPNNRINN 257
Query: 641 ----ISYEAEDLIRRLLTHSENRLGRHGGADEIKAHPFFSGVDWN 681
I+ +L++++L N ++IK HP+FS VDWN
Sbjct: 258 STSPINPLVINLVQKILVIEVN---ERISLEQIKRHPYFSKVDWN 299
>At1g51170 [R] KOG0610 Putative serine/threonine protein kinase
Length = 404
Score = 144 bits (362), Expect = 7e-34
Identities = 104/368 (28%), Positives = 168/368 (45%), Gaps = 49/368 (13%)
Query: 345 DDFNSVKVIGKGAFGEVRLVQKK----DTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLA 400
D +K++GKGA G V LV +A+K + KS + L + E +L
Sbjct: 20 DRLKVLKLLGKGATGTVFLVHDSVSDSSVSSPFALKLVDKS---SASSLRRARWEIQILR 76
Query: 401 G-----SDSPWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQ--IFTEDVTRFYMAE 453
+ +P++ L S + S+++ + + GGDL + R +F+ V +FY+AE
Sbjct: 77 RLSDDTNPNPFLPKLLASSESSEFIAWALPYCSGGDLNVLRQRQNDGVFSSSVIKFYLAE 136
Query: 454 CILAIEVIHKLGFIHRDIKPDNILIDIRGHIKLSDFGLSTGFHKTHDSSYYXXXXXXXXX 513
+ A++ +H +G +RD+KP+NIL+ GH+ L+DF LS +K +Y
Sbjct: 137 IVCALDHLHTMGIAYRDLKPENILLQESGHVTLTDFDLSCSLNKPTRPEFYHLSDPEPD- 195
Query: 514 XXXXXXXXXXXXXXXXXXXXPNETNNGNRNTMLVDAIHLTMTNRQQMQTWRKSRRLMAYS 573
PN +N + N + + + +RR +++S
Sbjct: 196 --------------------PNPESNLSHNKKSLRIFRQKKKKTKSARVNPITRRRLSFS 235
Query: 574 T-------VGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKI 626
VGT +YI+PE+ G+ DWW+LG + YE + G PF +ET+R +
Sbjct: 236 GGERSNSFVGTDEYISPEVIRGDGHDFAVDWWALGVLTYEMMYGETPFKGRNKKETFRNV 295
Query: 627 MNFEQTLQFPDDIHISYEAEDLIRRLLTHS-ENRLGRHGGADEIKAHPFFSGVDWNTIRQ 685
+ ++ P+ + DLIRRLL R G GA EIK H FF GV W + +
Sbjct: 296 L-----VKEPEFAGKPSDLTDLIRRLLVKDPTKRFGFWRGAAEIKEHAFFKGVRWELLTE 350
Query: 686 V-EAPYIP 692
V P+IP
Sbjct: 351 VLRPPFIP 358
>7295426 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 490
Score = 144 bits (362), Expect = 7e-34
Identities = 74/150 (49%), Positives = 103/150 (68%), Gaps = 4/150 (2%)
Query: 346 DFNSVKVIGKGAFGEVRLVQK---KDTGKIYAMKTLLKSEMY-NKDQLAHVKAERDVLAG 401
DF KV+GKG +G+V V+K +D K +AMK L K+ + N+ AH +AER++L
Sbjct: 76 DFELKKVLGKGGYGKVFQVRKTAGRDANKYFAMKVLKKASIVTNQKDTAHTRAERNILEA 135
Query: 402 SDSPWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVI 461
P++V L Y+FQ LYLI+E+L GG+L L R IF ED T FY++E ILA+ +
Sbjct: 136 VKHPFIVELVYAFQTDGKLYLILEYLSGGELFMHLEREGIFLEDTTCFYLSEIILALGHL 195
Query: 462 HKLGFIHRDIKPDNILIDIRGHIKLSDFGL 491
HKLG I+RD+KP+NIL+D +GH+KL+DFGL
Sbjct: 196 HKLGIIYRDLKPENILLDAQGHVKLTDFGL 225
Score = 97.1 bits (240), Expect = 9e-20
Identities = 57/152 (37%), Positives = 86/152 (56%), Gaps = 9/152 (5%)
Query: 569 LMAYSTVGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMN 628
++ ++ GT +Y+APEI G+G+ DWWSLGA+M++ L G PPF +E ++T I+
Sbjct: 234 IVTHTFCGTIEYMAPEILTRSGHGKAVDWWSLGALMFDMLTGVPPFTAENRKKTIETILK 293
Query: 629 FEQTLQFPDDIHISYEAEDLIRRLLTHSE-NRLGR-HGGADEIKAHPFFSGVDWNTI--R 684
+ L +++ EA DL+RRL+ E RLG A ++ HPFF V+W+ + R
Sbjct: 294 AKLNL----PAYLTPEARDLVRRLMKRQEPQRLGSGPEDAAAVQIHPFFKHVNWDDVLAR 349
Query: 685 QVEAPYIPKLSSVTDTRFFPTDELENVP-DSP 715
++E P P L S D F T +P DSP
Sbjct: 350 RLEPPIKPLLRSEDDVSQFDTRFTRQIPVDSP 381
>CE22045 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 580
Score = 143 bits (361), Expect = 9e-34
Identities = 74/163 (45%), Positives = 110/163 (67%), Gaps = 8/163 (4%)
Query: 345 DDFNSVKVIGKGAFGEVRLVQK---KDTGKIYAMKTLLKSEMY-NKDQLAHVKAERDVLA 400
+DF +KV+GKG +G+V V+K D G+I+AMK L K+ + N+ AH KAER++L
Sbjct: 81 EDFQLLKVLGKGGYGKVFQVRKTTGSDNGQIFAMKVLQKATIVRNQKDTAHTKAERNILE 140
Query: 401 GSDSPWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEV 460
SP++ L Y+FQ LYLI+E+L GG+L L R +F E+V +FY++E ++++E
Sbjct: 141 AVKSPFICDLLYAFQTGGKLYLILEYLSGGELFMHLEREGMFMENVAKFYLSEIVVSLEH 200
Query: 461 IHKLGFIHRDIKPDNILIDIRGHIKLSDFGLS----TGFHKTH 499
+H+ G I+RD+KP+NIL+D GH+KL+DFGL G KTH
Sbjct: 201 LHQQGIIYRDLKPENILLDAYGHVKLTDFGLCKEEIEGDQKTH 243
Score = 112 bits (280), Expect = 2e-24
Identities = 69/180 (38%), Positives = 97/180 (53%), Gaps = 26/180 (14%)
Query: 576 GTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQF 635
GT +Y+APEI + G+G+ DWWSLGA+M++ L G PPF +E ++T KI+ TL
Sbjct: 247 GTIEYMAPEILMRCGHGKAVDWWSLGALMFDMLTGGPPFTAENRRKTIDKILKGRLTL-- 304
Query: 636 PDDIHISYEAEDLIRRLL-THSENRLGRH-GGADEIKAHPFFSGVDWNTI--RQVEAPYI 691
++S EA DLI++LL H + RLG A+EIK+H FF DWN + RQ+EAP+
Sbjct: 305 --PAYLSNEARDLIKKLLKRHVDTRLGAGLSDAEEIKSHAFFKTTDWNLVYARQLEAPFK 362
Query: 692 PKLSSVTDTRFFPTDELENVP-DSPXXXXXXXXXXXXXXXXXGVPQSNAKEDLPFIGYTY 750
P + + DT F + P DSP + D PF+G+TY
Sbjct: 363 PNIENDEDTSLFDARFTKMTPVDSPCET-----------------NFSLNGDNPFVGFTY 405
>Hs4885549 [T] KOG0690 Serine/threonine protein kinase
Length = 479
Score = 142 bits (358), Expect = 2e-33
Identities = 74/183 (40%), Positives = 114/183 (61%), Gaps = 4/183 (2%)
Query: 313 QDWSEERKN----RQLASLGKKESQFXXXXXXXXXXDDFNSVKVIGKGAFGEVRLVQKKD 368
Q EER N Q+ ++G++E +DF+ +K++GKG FG+V LV++K
Sbjct: 110 QRQEEERMNCSPTSQIDNIGEEEMDASTTHHKRKTMNDFDYLKLLGKGTFGKVILVREKA 169
Query: 369 TGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDSPWVVSLYYSFQDSQYLYLIMEFLP 428
+GK YAMK L K + KD++AH E VL + P++ SL YSFQ L +ME++
Sbjct: 170 SGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNTRHPFLTSLKYSFQTKDRLCFVMEYVN 229
Query: 429 GGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKLGFIHRDIKPDNILIDIRGHIKLSD 488
GG+L L R ++F+ED TRFY AE + A++ +H ++RD+K +N+++D GHIK++D
Sbjct: 230 GGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHSGKIVYRDLKLENLMLDKDGHIKITD 289
Query: 489 FGL 491
FGL
Sbjct: 290 FGL 292
Score = 91.7 bits (226), Expect = 4e-18
Identities = 52/134 (38%), Positives = 81/134 (59%), Gaps = 12/134 (8%)
Query: 576 GTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQF 635
GTP+Y+APE+ YG+ DWW LG +MYE + G PF ++ ++ + I+ + ++F
Sbjct: 308 GTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELIL--MEDIKF 365
Query: 636 PDDIHISYEAEDLIRRLLTHSEN-RLGRHGGAD---EIKAHPFFSGVDWNTI--RQVEAP 689
P +S +A+ L+ LL N RLG GG D EI H FFSGV+W + +++ P
Sbjct: 366 PRT--LSSDAKSLLSGLLIKDPNKRLG--GGPDDAKEIMRHSFFSGVNWQDVYDKKLVPP 421
Query: 690 YIPKLSSVTDTRFF 703
+ P+++S TDTR+F
Sbjct: 422 FKPQVTSETDTRYF 435
>SPCC24B10.07 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 569
Score = 139 bits (351), Expect = 1e-32
Identities = 67/147 (45%), Positives = 102/147 (68%)
Query: 345 DDFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDS 404
D F +KV+GKG+FG+V V+K+DT +IYA+KT+ K+ + ++ ++ H AER VLA ++
Sbjct: 228 DAFELLKVVGKGSFGKVMQVRKRDTSRIYALKTMKKAHIVSRSEVDHTLAERTVLAQVNN 287
Query: 405 PWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKL 464
P++V L +SFQ LYL++ F+ GG+L L R F +FY+AE ++A+E +H+
Sbjct: 288 PFIVPLKFSFQSPGKLYLVLAFVNGGELFHHLQREGCFDTYRAKFYIAELLVALECLHEF 347
Query: 465 GFIHRDIKPDNILIDIRGHIKLSDFGL 491
I+RD+KP+NIL+D GHI L DFGL
Sbjct: 348 NVIYRDLKPENILLDYTGHIALCDFGL 374
Score = 119 bits (297), Expect = 2e-26
Identities = 61/140 (43%), Positives = 88/140 (62%), Gaps = 8/140 (5%)
Query: 576 GTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQF 635
GTP+Y+APE+ L GY + DWW+LG ++YE + G PPF E E YRKI+ + L+F
Sbjct: 390 GTPEYLAPELLLGHGYTKVVDWWTLGVLLYEMITGLPPFYDENINEMYRKIL--QDPLRF 447
Query: 636 PDDIHISYEAEDLIRRLLTHS-ENRLGRHGGADEIKAHPFFSGVDWNTI--RQVEAPYIP 692
PD +I +A+DL+ LLT + E RLG GGA EIK HPFF +DW + ++++ P+ P
Sbjct: 448 PD--NIDEKAKDLLSGLLTRAPEKRLG-SGGAQEIKNHPFFDDIDWKKLCAKKIQPPFKP 504
Query: 693 KLSSVTDTRFFPTDELENVP 712
+ S DT F ++ +P
Sbjct: 505 SVESAIDTSNFDSEFTSEIP 524
>SPAC1B9.02c [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 696
Score = 139 bits (349), Expect = 2e-32
Identities = 69/151 (45%), Positives = 102/151 (66%), Gaps = 3/151 (1%)
Query: 345 DDFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGS-- 402
+DF ++++IGKG FG+V LV+K DT +IYAMK + K + K ++ H ER++L +
Sbjct: 300 EDFTALRLIGKGTFGQVYLVRKNDTNRIYAMKKISKKLIVRKKEVTHTLGERNILVRTSL 359
Query: 403 -DSPWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVI 461
+SP++V L +SFQ + LYLI +++ GG+L L F E +FY+AE +LA+E +
Sbjct: 360 DESPFIVGLKFSFQTASDLYLITDYMSGGELFWHLQHEGRFPEQRAKFYIAELVLALEHL 419
Query: 462 HKLGFIHRDIKPDNILIDIRGHIKLSDFGLS 492
HK I+RD+KP+NIL+D GHI L DFGLS
Sbjct: 420 HKHDIIYRDLKPENILLDADGHIALCDFGLS 450
Score = 85.9 bits (211), Expect = 2e-16
Identities = 46/132 (34%), Positives = 77/132 (57%), Gaps = 7/132 (5%)
Query: 576 GTPDYIAPEIFLY-QGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQ 634
GT +Y+APE+ L +GY ++ D+WSLG +++E GW PF + Q+ YR I + ++
Sbjct: 465 GTTEYLAPEVLLEDKGYTKQVDFWSLGVLVFEMCCGWSPFYAPDVQQMYRNIAFGK--VR 522
Query: 635 FPDDIHISYEAEDLIRRLLTHSEN-RLGRHGGADEIKAHPFFSGVDWNTI--RQVEAPYI 691
FP + +S E +R LL + N RLG E+K HPFF+ ++W+ + ++V+ P+
Sbjct: 523 FPKGV-LSSEGRSFVRGLLNRNPNHRLGAVADTTELKEHPFFADINWDLLSKKKVQPPFK 581
Query: 692 PKLSSVTDTRFF 703
P + + D F
Sbjct: 582 PNVQNDLDVSNF 593
>Hs17455844 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 1139
Score = 138 bits (348), Expect = 3e-32
Identities = 64/147 (43%), Positives = 101/147 (68%)
Query: 346 DFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDSP 405
DF ++K+I GA+G V LV+ +DT + +A+K + K + ++Q+ V ERD+L +++P
Sbjct: 196 DFETIKLISNGAYGAVYLVRHRDTRQRFAIKKINKQNLILRNQIQQVFVERDILTFAENP 255
Query: 406 WVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKLG 465
+VVS++ SF+ ++L ++ME++ GGD T+L D+ R Y AE +LA+E +H G
Sbjct: 256 FVVSMFCSFETRRHLCMVMEYVEGGDCATLLKNMGPLPVDMARLYFAETVLALEYLHNYG 315
Query: 466 FIHRDIKPDNILIDIRGHIKLSDFGLS 492
+HRD+KPDN+LI GHIKL+DFGLS
Sbjct: 316 IVHRDLKPDNLLITSLGHIKLTDFGLS 342
Score = 118 bits (295), Expect = 4e-26
Identities = 59/153 (38%), Positives = 95/153 (61%), Gaps = 5/153 (3%)
Query: 555 TNRQQMQTWRKSRRLMAYSTVGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPF 614
TN + + +R + GTP+YIAPE+ QGYG+ DWW++G ++YE L+G PF
Sbjct: 351 TNLYEGHIEKDAREFIDKQVCGTPEYIAPEVIFRQGYGKPVDWWAMGVVLYEFLVGCVPF 410
Query: 615 CSETPQETYRKIMNFEQTLQFPD-DIHISYEAEDLIRRLLTHSE-NRLGRHGGADEIKAH 672
+TP+E + ++++ E + +P+ D + +A+DLI RLL S +RLG GG E+K H
Sbjct: 411 FGDTPEELFGQVVSDE--IMWPEGDEALPADAQDLITRLLRQSPLDRLGT-GGTHEVKQH 467
Query: 673 PFFSGVDWNTIRQVEAPYIPKLSSVTDTRFFPT 705
PFF +DW + + +A ++P+L + DT +F T
Sbjct: 468 PFFLALDWAGLLRHKAEFVPQLEAEDDTSYFDT 500
>Hs15619015 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 351
Score = 138 bits (348), Expect = 3e-32
Identities = 62/148 (41%), Positives = 102/148 (68%)
Query: 345 DDFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDS 404
D F ++ +G G+FG V LV+ ++TG YAMK L K ++ Q+ H+ E+ +L D
Sbjct: 42 DQFERLRTLGMGSFGRVMLVRHQETGGHYAMKILNKQKVVKMKQVEHILNEKRILQAIDF 101
Query: 405 PWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKL 464
P++V L +SF+D+ YLYL+ME++PGG++ + L R F+E FY A+ +LA++ +H L
Sbjct: 102 PFLVKLQFSFKDNSYLYLVMEYVPGGEMFSRLQRVGRFSEPHACFYAAQVVLAVQYLHSL 161
Query: 465 GFIHRDIKPDNILIDIRGHIKLSDFGLS 492
IHRD+KP+N+LID +G+++++DFG +
Sbjct: 162 DLIHRDLKPENLLIDQQGYLQVTDFGFA 189
Score = 95.5 bits (236), Expect = 3e-19
Identities = 53/144 (36%), Positives = 83/144 (56%), Gaps = 8/144 (5%)
Query: 572 YSTVGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQ 631
++ GTP+Y+APEI L +GY + DWW+LG ++YE +G+PPF ++ P + Y KI++
Sbjct: 197 WTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAVGFPPFYADQPIQIYEKIVS--G 254
Query: 632 TLQFPDDIHISYEAEDLIRRLL-THSENRLGR-HGGADEIKAHPFFSGVDWNTI--RQVE 687
++FP +S + + L+R LL R G G +IK H +F+ W I ++VE
Sbjct: 255 RVRFPS--KLSSDLKHLLRSLLQVDLTKRFGNLRNGVGDIKNHKWFATTSWIAIYEKKVE 312
Query: 688 APYIPKLSSVTDTRFFPTDELENV 711
AP+IPK + D F E E +
Sbjct: 313 APFIPKYTGPGDASNFDDYEEEEL 336
>YHR205w [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 824
Score = 138 bits (347), Expect = 4e-32
Identities = 69/161 (42%), Positives = 106/161 (64%), Gaps = 3/161 (1%)
Query: 346 DFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVL---AGS 402
DF ++++GKG FG+V V+KKDT +IYAMK L K + K+++AH ER++L A
Sbjct: 411 DFEVLRLLGKGTFGQVYQVKKKDTQRIYAMKVLSKKVIVKKNEIAHTIGERNILVTTASK 470
Query: 403 DSPWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIH 462
SP++V L +SFQ LYL+ +++ GG+L L + F+ED +FY+AE +LA+E +H
Sbjct: 471 SSPFIVGLKFSFQTPTDLYLVTDYMSGGELFWHLQKEGRFSEDRAKFYIAELVLALEHLH 530
Query: 463 KLGFIHRDIKPDNILIDIRGHIKLSDFGLSTGFHKTHDSSY 503
++RD+KP+NIL+D G+I L DFGLS K +++
Sbjct: 531 DNDIVYRDLKPENILLDANGNIALCDFGLSKADLKDRTNTF 571
Score = 94.7 bits (234), Expect = 5e-19
Identities = 51/132 (38%), Positives = 81/132 (60%), Gaps = 7/132 (5%)
Query: 576 GTPDYIAPEIFLYQ-GYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQ 634
GT +Y+APE+ L + GY + D+WSLG +++E GW PF +E Q+ Y+KI + ++
Sbjct: 573 GTTEYLAPELLLDETGYTKMVDFWSLGVLIFEMCCGWSPFFAENNQKMYQKIAFGK--VK 630
Query: 635 FPDDIHISYEAEDLIRRLLTHS-ENRLGRHGGADEIKAHPFFSGVDWNTIRQ--VEAPYI 691
FP D+ +S E ++ LL + ++RLG E++AHPFF+ +DW ++Q + P+
Sbjct: 631 FPRDV-LSQEGRSFVKGLLNRNPKHRLGAIDDGRELRAHPFFADIDWEALKQKKIPPPFK 689
Query: 692 PKLSSVTDTRFF 703
P L S TDT F
Sbjct: 690 PHLVSETDTSNF 701
>7294770 [T] KOG0603 Ribosomal protein S6 kinase
Length = 1207
Score = 138 bits (347), Expect = 4e-32
Identities = 81/184 (44%), Positives = 111/184 (60%), Gaps = 5/184 (2%)
Query: 314 DWSEERKNRQLASLGKKESQFXXXXXXXXXXDDFNSVKVIGKGAFGEVRLVQK---KDTG 370
D E R L ++ + +DF ++V+G GA+G V LV+K D G
Sbjct: 228 DLDNEAHQRDLEAVTDLKYYVKLYSDEAVSLNDFKIIRVLGTGAYGRVFLVRKLTRHDAG 287
Query: 371 KIYAMKTLLKSEMYNKDQLA-HVKAERDVL-AGSDSPWVVSLYYSFQDSQYLYLIMEFLP 428
K+YAMK L K + K + A H K ER VL A +P++VSL+Y+FQ S LYL+++F
Sbjct: 288 KLYAMKVLNKITVVQKRKTAEHTKTERVVLEAIQRNPFLVSLHYAFQSSSKLYLVLDFAN 347
Query: 429 GGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKLGFIHRDIKPDNILIDIRGHIKLSD 488
GG+L T L + F E R Y+AE +LA+E +H+LG I+RDIK +NIL+D GHI LSD
Sbjct: 348 GGELFTHLYHSENFEESRVRVYIAEVVLALEQLHQLGIIYRDIKLENILLDGEGHIVLSD 407
Query: 489 FGLS 492
FGLS
Sbjct: 408 FGLS 411
Score = 89.0 bits (219), Expect = 3e-17
Identities = 55/179 (30%), Positives = 86/179 (47%), Gaps = 6/179 (3%)
Query: 543 NTMLVDAIHLTMTNRQQMQTWRKSRRLMAYSTVGTPDYIAPEIFLY--QGYGQECDWWSL 600
N +L H+ +++ + A+S GT +Y+APEI G+ DWWS+
Sbjct: 394 NILLDGEGHIVLSDFGLSKILTAENEYRAHSFCGTLEYMAPEIIRTGPPGHDSAVDWWSV 453
Query: 601 GAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQFPDDIHISYEAEDLIRRLLTHSENRL 660
G + +E L G PF + Q +I Q Q S A D + ++L + R
Sbjct: 454 GVLTFELLTGASPFATSDGQVQQSEISRRIQKEQPMIPSSFSANARDFVLKMLEKNPKRR 513
Query: 661 --GRHGGADEIKAHPFFSGVDWNTIR--QVEAPYIPKLSSVTDTRFFPTDELENVPDSP 715
G H A EIK HPFF+G++W +R + +APY P L++ D + F + + VP+ P
Sbjct: 514 LGGNHRDASEIKEHPFFNGINWQELRTKRRKAPYKPTLTAEDDVQNFSNEFTDQVPEDP 572
Score = 56.6 bits (135), Expect = 1e-07
Identities = 42/148 (28%), Positives = 69/148 (46%), Gaps = 9/148 (6%)
Query: 345 DDFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDS 404
DD GA+G V T ++ K + S+ + A + D +
Sbjct: 621 DDLELGTRTSNGAYGTCHFVVDSSTDLVFLAKIIPLSKFRPSEVDALISCALDTTNHKN- 679
Query: 405 PWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKL 464
+VS + +F++ +++ME+L G +L T IR ED R + ++A+ IH
Sbjct: 680 --IVSYHGTFREKCETWIVMEYLSGPEL-TASIRMD---EDSCREIFLQLVMAVRHIHSK 733
Query: 465 GFIHRDIKPDNILIDIRGH--IKLSDFG 490
FIH D+KP+NI+ + R +KL DFG
Sbjct: 734 HFIHGDLKPENIMFENREDRTVKLIDFG 761
>Hs14149671 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 1734
Score = 137 bits (346), Expect = 5e-32
Identities = 64/148 (43%), Positives = 99/148 (66%)
Query: 345 DDFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDS 404
+DF ++K+I GA+G V LV+ K T + +AMK + K + ++Q+ ERD+L +++
Sbjct: 510 EDFETIKLISNGAYGAVFLVRHKSTRQRFAMKKINKQNLILRNQIQQAFVERDILTFAEN 569
Query: 405 PWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKL 464
P+VVS++ SF ++L ++ME++ GGD T+L D+ R Y AE +LA+E +H
Sbjct: 570 PFVVSMFCSFDTKRHLCMVMEYVEGGDCATLLKNIGALPVDMVRLYFAETVLALEYLHNY 629
Query: 465 GFIHRDIKPDNILIDIRGHIKLSDFGLS 492
G +HRD+KPDN+LI GHIKL+DFGLS
Sbjct: 630 GIVHRDLKPDNLLITSMGHIKLTDFGLS 657
Score = 118 bits (296), Expect = 3e-26
Identities = 61/153 (39%), Positives = 96/153 (61%), Gaps = 5/153 (3%)
Query: 555 TNRQQMQTWRKSRRLMAYSTVGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPF 614
TN + + +R + GTP+YIAPE+ L QGYG+ DWW++G I+YE L+G PF
Sbjct: 666 TNLYEGHIEKDAREFLDKQVCGTPEYIAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPF 725
Query: 615 CSETPQETYRKIMNFEQTLQFPD-DIHISYEAEDLIRRLLTHSE-NRLGRHGGADEIKAH 672
+TP+E + ++++ E + +P+ D + +A+DL +LL + RLG G A E+K H
Sbjct: 726 FGDTPEELFGQVISDE--IVWPEGDEALPPDAQDLTSKLLHQNPLERLGT-GSAYEVKQH 782
Query: 673 PFFSGVDWNTIRQVEAPYIPKLSSVTDTRFFPT 705
PFF+G+DW + + +A +IP+L S DT +F T
Sbjct: 783 PFFTGLDWTGLLRQKAEFIPQLESEDDTSYFDT 815
>7300106 [T] KOG0690 Serine/threonine protein kinase
Length = 530
Score = 137 bits (346), Expect = 5e-32
Identities = 68/147 (46%), Positives = 101/147 (68%)
Query: 345 DDFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDS 404
++F +KV+GKG FG+V L ++K T K+YA+K L K + KD++AH E VL ++
Sbjct: 183 ENFEFLKVLGKGTFGKVILCREKATAKLYAIKILKKEVIIQKDEVAHTLTESRVLKSTNH 242
Query: 405 PWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKL 464
P+++SL YSFQ + L +M+++ GG+L L +IFTED TRFY AE I A+ +H
Sbjct: 243 PFLISLKYSFQTNDRLCFVMQYVNGGELFWHLSHERIFTEDRTRFYGAEIISALGYLHSQ 302
Query: 465 GFIHRDIKPDNILIDIRGHIKLSDFGL 491
G I+RD+K +N+L+D GHIK++DFGL
Sbjct: 303 GIIYRDLKLENLLLDKDGHIKVADFGL 329
Score = 90.9 bits (224), Expect = 7e-18
Identities = 54/150 (36%), Positives = 86/150 (57%), Gaps = 16/150 (10%)
Query: 576 GTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQF 635
GTP+Y+APE+ YGQ DWW G +MYE + G PF + + I+ + ++F
Sbjct: 345 GTPEYLAPEVLDDNDYGQAVDWWGTGVVMYEMICGRLPFYNRDHDVLFTLIL--VEEVKF 402
Query: 636 PDDIHISYEAEDLIRRLLTHS-ENRLGRHGGAD---EIKAHPFFSGVDWN--TIRQVEAP 689
P +I+ EA++L+ LL + RLG GG D EI+AHPFF+ ++W ++++ P
Sbjct: 403 PR--NITDEAKNLLAGLLAKDPKKRLG--GGKDDVKEIQAHPFFASINWTDLVLKKIPPP 458
Query: 690 YIPKLSSVTDTRFFPT----DELENVPDSP 715
+ P+++S TDTR+F + +E P P
Sbjct: 459 FKPQVTSDTDTRYFDKEFTGESVELTPPDP 488
>YFL033c [R] KOG0605 NDR and related serine/threonine kinases
Length = 1770
Score = 137 bits (345), Expect = 6e-32
Identities = 66/148 (44%), Positives = 101/148 (67%), Gaps = 1/148 (0%)
Query: 346 DFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVL-AGSDS 404
D++ +K I KGA+G V L +KK TG +A+K L KS+M K+Q+ +VK+ER ++ SD
Sbjct: 793 DYDILKPISKGAYGSVYLARKKLTGDYFAIKVLRKSDMIAKNQVTNVKSERAIMMVQSDK 852
Query: 405 PWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKL 464
P+V L+ SFQ+ L+L+ME+LPGGDL T++ + + Y+ E ++ + +H+
Sbjct: 853 PYVARLFASFQNKDNLFLVMEYLPGGDLATLIKMMGYLPDQWAKQYLTEIVVGVNDMHQN 912
Query: 465 GFIHRDIKPDNILIDIRGHIKLSDFGLS 492
G IH D+KP+N+LID GH+KL+DFGLS
Sbjct: 913 GIIHHDLKPENLLIDNAGHVKLTDFGLS 940
Score = 104 bits (259), Expect = 6e-22
Identities = 55/137 (40%), Positives = 84/137 (61%), Gaps = 12/137 (8%)
Query: 576 GTPDYIAPEIFLYQGY-GQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQ 634
GTPDY+APE +G ++CDWWS+G I +E L+G+PPF +ETP ++KI++ +Q
Sbjct: 1149 GTPDYLAPETIEGKGEDNKQCDWWSVGCIFFELLLGYPPFHAETPDAVFKKILS--GVIQ 1206
Query: 635 FPDDIH-------ISYEAEDLIRRLL-THSENRLGRHGGADEIKAHPFFSGVDWNTIRQV 686
+P+ + ++ EA+DLI +LL RLG G EIK HP+F VDW+ +
Sbjct: 1207 WPEFKNEEEEREFLTPEAKDLIEKLLVVDPAKRLGAK-GIQEIKDHPYFKNVDWDHVYDE 1265
Query: 687 EAPYIPKLSSVTDTRFF 703
EA ++P + + DT +F
Sbjct: 1266 EASFVPTIDNPEDTDYF 1282
>YDR490c [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 766
Score = 137 bits (345), Expect = 6e-32
Identities = 94/339 (27%), Positives = 156/339 (45%), Gaps = 70/339 (20%)
Query: 346 DFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAG-SDS 404
DF + +G G++ V L +D+GK YA+K L K + + ++ +V E+ L + +
Sbjct: 124 DFKFGEQLGDGSYSSVVLATARDSGKKYAVKVLSKEYLIRQKKVKYVTVEKLALQKLNGT 183
Query: 405 PWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKL 464
+ L+++FQD LY ++E+ P GD + ++ ++ E R+Y ++ I A++ +H +
Sbjct: 184 KGIFKLFFTFQDEASLYFLLEYAPHGDFLGLIKKYGSLNETCARYYASQIIDAVDSLHNI 243
Query: 465 GFIHRDIKPDNILIDIRGHIKLSDFGLSTGFHKTHDSSYYXXXXXXXXXXXXXXXXXXXX 524
G IHRDIKP+NIL+D +KL+DFG
Sbjct: 244 GIIHRDIKPENILLDKNMKVKLTDFG---------------------------------- 269
Query: 525 XXXXXXXXXPNETNNGNRNTMLVDAIHLTMTNRQQMQTWRKSRRLMAYSTVGTPDYIAPE 584
P E +N T + + KS+ S VGT +Y++PE
Sbjct: 270 ----TAKILPEEPSN-------------TADGKPYFDLYAKSK-----SFVGTAEYVSPE 307
Query: 585 IFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQ--TLQFPDDIHIS 642
+ CD W+ G I+Y+ L G PPF + T++K+M + T FP +
Sbjct: 308 LLNDNYTDSRCDIWAFGCILYQMLAGKPPFKAANEYLTFQKVMKIQYAFTAGFPQIV--- 364
Query: 643 YEAEDLIRRLLTHSEN-RLGRHGGADEIKAHPFFSGVDW 680
+DL+++LL N RL +IKAH FF V++
Sbjct: 365 ---KDLVKKLLVRDPNDRL----TIKQIKAHLFFHEVNF 396
>SPCC4G3.08 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 436
Score = 137 bits (345), Expect = 6e-32
Identities = 66/148 (44%), Positives = 101/148 (67%), Gaps = 1/148 (0%)
Query: 346 DFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQ-LAHVKAERDVLAGSDS 404
DF + V+G+G++G+V LV++K+TG+++A K L K+ + + + L K ER +L
Sbjct: 90 DFQPLTVLGRGSYGKVLLVKQKNTGRLFAQKQLKKASIVLRAKGLEQTKNERQILEEVRH 149
Query: 405 PWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKL 464
P++ LYY+FQD LYLI+++ PGG+L + L ++ EDV FY AE LA+ +HKL
Sbjct: 150 PFICRLYYAFQDHDRLYLILQYAPGGELFSHLAEQRMLPEDVVAFYTAELTLALIHLHKL 209
Query: 465 GFIHRDIKPDNILIDIRGHIKLSDFGLS 492
G ++RD+KP+N L+D GHI L+DFGLS
Sbjct: 210 GIVYRDLKPENCLLDAEGHILLTDFGLS 237
Score = 81.3 bits (199), Expect = 5e-15
Identities = 44/130 (33%), Positives = 70/130 (53%), Gaps = 10/130 (7%)
Query: 573 STVGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQT 632
S VGT +Y APEI L Q Y DWWS+G ++++ L G PPF + + KI +
Sbjct: 248 SFVGTEEYCAPEILLEQPYDHAVDWWSMGILIFDLLTGSPPFTANNHKRIMEKITRAKPN 307
Query: 633 LQFPDDIHISYEAEDLIRRLL-THSENRLGRHG---GADEIKAHPFFSGVDWNTI--RQV 686
+ F +++ +A D+I + L + + RLG G G D IK H + +DWN + R +
Sbjct: 308 IPF----YVTSDARDIINKFLKKNPKQRLGADGPEKGYDAIKKHRIYRRIDWNKLEKRML 363
Query: 687 EAPYIPKLSS 696
P +P +++
Sbjct: 364 PPPIVPCITN 373
>7295638 [T] KOG0603 Ribosomal protein S6 kinase
Length = 911
Score = 137 bits (344), Expect = 8e-32
Identities = 72/149 (48%), Positives = 103/149 (68%), Gaps = 4/149 (2%)
Query: 347 FNSVKVIGKGAFGEVRLVQK---KDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSD 403
F ++V+G+G+FG+V LV+K KD G +YAMK L K+ + KD++ ER +LA
Sbjct: 199 FELLRVLGEGSFGKVFLVRKIIGKDAGTLYAMKVLKKATLKVKDRVRSTN-ERKILADVG 257
Query: 404 SPWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHK 463
++V L+Y+FQ LYLI++FL GGDL T L + +FTE+ +FY+AE LA+ +H
Sbjct: 258 HAFIVRLHYAFQTPGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALAMNHLHT 317
Query: 464 LGFIHRDIKPDNILIDIRGHIKLSDFGLS 492
LG I+RD+KP+NIL+D GHI L+DFGLS
Sbjct: 318 LGIIYRDLKPENILLDEHGHIALTDFGLS 346
Score = 91.7 bits (226), Expect = 4e-18
Identities = 60/149 (40%), Positives = 84/149 (56%), Gaps = 10/149 (6%)
Query: 572 YSTVGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQ 631
YS GT +Y+APEI +G+ DWWS G +MYE L G PF +T QET +I+
Sbjct: 356 YSFCGTVEYMAPEIVNRKGHDFAADWWSFGVLMYEMLTGNLPFHGQTRQETMNQIL--RS 413
Query: 632 TLQFPDDIHISYEAEDLIRRLLTHS-ENRLGRHG-GADEIKAHPFFSGVDWNTI--RQVE 687
L P+ ++S EA+ L+R L + +NRLG G +IKAH FF+ +DW + +QV
Sbjct: 414 KLGMPE--NLSPEAQSLLRALFKRNPQNRLGAGAQGILDIKAHCFFATIDWVRLERKQVR 471
Query: 688 APYIPKLSSVTDTRFFPTDELENVP-DSP 715
P+IP +S D +F + P DSP
Sbjct: 472 PPFIPAVSR-DDAFYFDVEYTSKSPRDSP 499
Score = 66.6 bits (161), Expect = 1e-10
Identities = 36/135 (26%), Positives = 69/135 (50%), Gaps = 3/135 (2%)
Query: 346 DFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDV---LAGS 402
++N ++ +G+G F RL + + + K YA+K + K+ + +V L
Sbjct: 567 EYNLLQELGRGTFSVCRLCEHRASKKHYAVKVIEKAAVAAASTSTSADCWEEVEIMLRYG 626
Query: 403 DSPWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIH 462
+ P +V+LY ++D+ YL+ME L GG+L+ ++ E + A+ +H
Sbjct: 627 NHPNIVTLYSVYEDAGSAYLVMELLKGGELLDRILAVGQMCESEASAVLRTIASAVAYLH 686
Query: 463 KLGFIHRDIKPDNIL 477
+ G +HRD+KP N++
Sbjct: 687 EHGVVHRDLKPSNMI 701
Score = 48.9 bits (115), Expect = 3e-05
Identities = 27/80 (33%), Positives = 44/80 (54%), Gaps = 3/80 (3%)
Query: 577 TPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCS---ETPQETYRKIMNFEQTL 633
T +++APE+ QGY CD WSLG ++Y L G PF S ++P ++I + +
Sbjct: 736 TANFVAPEVLKRQGYDLACDIWSLGVLLYIMLSGRTPFASTPNDSPDVILKRIGSGQIDF 795
Query: 634 QFPDDIHISYEAEDLIRRLL 653
IS A++L+R++L
Sbjct: 796 TSSRWALISVPAKELLRQML 815
>Hs8923754 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 414
Score = 136 bits (343), Expect = 1e-31
Identities = 63/149 (42%), Positives = 102/149 (68%)
Query: 345 DDFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDS 404
D F ++ IGKG+FG+V +VQK+DT K+YAMK + K + +D++ +V E ++ G +
Sbjct: 21 DHFQILRAIGKGSFGKVCIVQKRDTKKMYAMKYMNKQKCIERDEVRNVFRELQIMQGLEH 80
Query: 405 PWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKL 464
P++V+L+YSFQD + ++++++ L GGDL L + FTE + Y+ E LA+E + +
Sbjct: 81 PFLVNLWYSFQDEEDMFMVVDLLLGGDLRYHLQQNVHFTEGTVKLYICELALALEYLQRY 140
Query: 465 GFIHRDIKPDNILIDIRGHIKLSDFGLST 493
IHRDIKPDNIL+D GH+ ++DF ++T
Sbjct: 141 HIIHRDIKPDNILLDEHGHVHITDFNIAT 169
Score = 54.7 bits (130), Expect = 5e-07
Identities = 45/154 (29%), Positives = 70/154 (45%), Gaps = 25/154 (16%)
Query: 571 AYSTVGTPDYIAPEIF-LYQ----GYGQECDWWSLGAIMYECLIGWPPF--CSETPQETY 623
A S GT Y+APE+F +Y GY DWWSLG YE L GW P+ S TP +
Sbjct: 177 ASSMAGTKPYMAPEVFQVYMDRGPGYSYPVDWWSLGITAYELLRGWRPYEIHSVTPIDEI 236
Query: 624 RKIMNFEQTLQFPDDIHISYE----AEDLIRRLLTHSENRLGRHGGADEIKAHPFFSGVD 679
+ E+ +H S L+R+LLT R +I++ P+ + ++
Sbjct: 237 LNMFKVER-------VHYSSTWCKGMVALLRKLLTKDPE--SRVSSLHDIQSVPYLADMN 287
Query: 680 WNTI--RQVEAPYIPKLSSVTDTRFFPTDELENV 711
W+ + + + ++P + PT ELE +
Sbjct: 288 WDAVFKKALMPGFVPNKGRLNCD---PTFELEEM 318
>CE15475 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 375
Score = 136 bits (343), Expect = 1e-31
Identities = 62/148 (41%), Positives = 101/148 (67%)
Query: 345 DDFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDS 404
DDF+ +K +G G+FG V LV+ K +G YAMK L K ++ Q+ H E+ +L D
Sbjct: 50 DDFDRIKTLGTGSFGRVMLVKHKQSGNYYAMKILDKQKVVKLKQVEHTLNEKRILQAIDF 109
Query: 405 PWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKL 464
P++V++ +SF+D+ LY+++EF+ GG++ + L R F+E +RFY A+ +LA E +H L
Sbjct: 110 PFLVNMTFSFKDNSNLYMVLEFISGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHSL 169
Query: 465 GFIHRDIKPDNILIDIRGHIKLSDFGLS 492
I+RD+KP+N+LID G++K++DFG +
Sbjct: 170 DLIYRDLKPENLLIDSTGYLKITDFGFA 197
Score = 89.7 bits (221), Expect = 1e-17
Identities = 54/151 (35%), Positives = 79/151 (51%), Gaps = 24/151 (15%)
Query: 572 YSTVGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQ 631
++ GTP+Y+APEI L +GY + DWW+LG ++YE G+PPF ++ P + Y KI++ +
Sbjct: 205 WTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGK- 263
Query: 632 TLQFPDDIHISYEAEDLIRRLL-THSENRLGR-HGGADEIKAHPFFSGVDWNTI------ 683
++FP H S E +DL++ LL R G G +IK H +F DW I
Sbjct: 264 -VKFPS--HFSNELKDLLKNLLQVDLTKRYGNLKNGVADIKNHKWFGSTDWIAIYQKKIT 320
Query: 684 -----------RQVEAPYIPKLSSVTDTRFF 703
R EA Y P++ DTR F
Sbjct: 321 PPSFSKGESNGRLFEALY-PRVDGPADTRHF 350
>CE15473 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 359
Score = 136 bits (343), Expect = 1e-31
Identities = 62/148 (41%), Positives = 101/148 (67%)
Query: 345 DDFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDS 404
DDF+ +K +G G+FG V LV+ K +G YAMK L K ++ Q+ H E+ +L D
Sbjct: 50 DDFDRIKTLGTGSFGRVMLVKHKQSGNYYAMKILDKQKVVKLKQVEHTLNEKRILQAIDF 109
Query: 405 PWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKL 464
P++V++ +SF+D+ LY+++EF+ GG++ + L R F+E +RFY A+ +LA E +H L
Sbjct: 110 PFLVNMTFSFKDNSNLYMVLEFISGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHSL 169
Query: 465 GFIHRDIKPDNILIDIRGHIKLSDFGLS 492
I+RD+KP+N+LID G++K++DFG +
Sbjct: 170 DLIYRDLKPENLLIDSTGYLKITDFGFA 197
Score = 100 bits (249), Expect = 8e-21
Identities = 55/145 (37%), Positives = 84/145 (57%), Gaps = 10/145 (6%)
Query: 572 YSTVGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQ 631
++ GTP+Y+APEI L +GY + DWW+LG ++YE G+PPF ++ P + Y KI++ +
Sbjct: 205 WTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGK- 263
Query: 632 TLQFPDDIHISYEAEDLIRRLL-THSENRLGR-HGGADEIKAHPFFSGVDWNTI--RQVE 687
++FP H S E +DL++ LL R G G +IK H +F DW I +++E
Sbjct: 264 -VKFPS--HFSNELKDLLKNLLQVDLTKRYGNLKNGVADIKNHKWFGSTDWIAIYQKKIE 320
Query: 688 APYIPKLSSVTDTRFFPTDELENVP 712
AP++PK D F D+ E P
Sbjct: 321 APFLPKCRGPGDASNF--DDYEEEP 343
>Hs4506739 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 495
Score = 135 bits (341), Expect = 2e-31
Identities = 72/149 (48%), Positives = 99/149 (66%), Gaps = 4/149 (2%)
Query: 347 FNSVKVIGKGAFG---EVRLVQKKDTGKIYAMKTLLKSEMY-NKDQLAHVKAERDVLAGS 402
F ++V+GKG +G +VR VQ + GKIYAMK L K+++ N AH +AER++L
Sbjct: 80 FELLRVLGKGGYGKVFQVRKVQGTNLGKIYAMKVLRKAKIVRNAKDTAHTRAERNILESV 139
Query: 403 DSPWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIH 462
P++V L Y+FQ LYLI+E L GG+L T L R IF ED FY+AE LA+ +H
Sbjct: 140 KHPFIVELAYAFQTGGKLYLILECLSGGELFTHLEREGIFLEDTACFYLAEITLALGHLH 199
Query: 463 KLGFIHRDIKPDNILIDIRGHIKLSDFGL 491
G I+RD+KP+NI++ +GHIKL+DFGL
Sbjct: 200 SQGIIYRDLKPENIMLSSQGHIKLTDFGL 228
Score = 90.5 bits (223), Expect = 9e-18
Identities = 51/151 (33%), Positives = 86/151 (56%), Gaps = 9/151 (5%)
Query: 570 MAYSTVGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNF 629
+ ++ GT +Y+APEI + G+ + DWWSLGA+MY+ L G PPF +E ++T KI+
Sbjct: 238 VTHTFCGTIEYMAPEILVRSGHNRAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIRG 297
Query: 630 EQTLQFPDDIHISYEAEDLIRRLLTHSENRL--GRHGGADEIKAHPFFSGVDWNTIR--Q 685
+ L +++ +A DL+++ L + ++ G G A +++ HPFF ++W+ + +
Sbjct: 298 KLAL----PPYLTPDARDLVKKFLKRNPSQRIGGGPGDAADVQRHPFFRHMNWDDLLAWR 353
Query: 686 VEAPYIPKLSSVTDTRFFPTDELENVP-DSP 715
V+ P+ P L S D F T P DSP
Sbjct: 354 VDPPFRPCLQSEEDVSQFDTRFTRQTPVDSP 384
>Hs20543401 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 2092
Score = 135 bits (341), Expect = 2e-31
Identities = 61/147 (41%), Positives = 99/147 (66%)
Query: 346 DFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDSP 405
DF ++K+I GA+G V V+ K++ + +AMK + K + ++Q+ ERD+L +++P
Sbjct: 38 DFETIKLISNGAYGAVYFVRHKESRQRFAMKKINKQNLILRNQIQQAFVERDILTFAENP 97
Query: 406 WVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKLG 465
+VVS+Y SF+ ++L ++ME++ GGD T++ D+ R Y AE +LA+E +H G
Sbjct: 98 FVVSMYCSFETRRHLCMVMEYVEGGDCATLMKNMGPLPVDMARMYFAETVLALEYLHNYG 157
Query: 466 FIHRDIKPDNILIDIRGHIKLSDFGLS 492
+HRD+KPDN+L+ GHIKL+DFGLS
Sbjct: 158 IVHRDLKPDNLLVTSMGHIKLTDFGLS 184
Score = 117 bits (293), Expect = 7e-26
Identities = 62/153 (40%), Positives = 95/153 (61%), Gaps = 5/153 (3%)
Query: 555 TNRQQMQTWRKSRRLMAYSTVGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPF 614
TN + + +R + GTP+YIAPE+ L QGYG+ DWW++G I+YE L+G PF
Sbjct: 193 TNLYEGHIEKDAREFLDKQVCGTPEYIAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPF 252
Query: 615 CSETPQETYRKIMNFEQTLQFPD-DIHISYEAEDLIRRLLTHSE-NRLGRHGGADEIKAH 672
+TP+E + ++++ E + +P+ D +A+DLI LL + RLG GGA E+K H
Sbjct: 253 FGDTPEELFGQVISDE--INWPEKDEAPPPDAQDLITLLLRQNPLERLGT-GGAYEVKQH 309
Query: 673 PFFSGVDWNTIRQVEAPYIPKLSSVTDTRFFPT 705
FF +DWN++ + +A +IP+L S DT +F T
Sbjct: 310 RFFRSLDWNSLLRQKAEFIPQLESEDDTSYFDT 342
>Hs4506055 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 351
Score = 135 bits (340), Expect = 2e-31
Identities = 66/184 (35%), Positives = 113/184 (60%), Gaps = 2/184 (1%)
Query: 311 ASQDWSEERKNRQLASLGKKE--SQFXXXXXXXXXXDDFNSVKVIGKGAFGEVRLVQKKD 368
A++ SE+ ++ + K++ ++ D F +K +G G+FG V LV+ K+
Sbjct: 6 AAKKGSEQESVKEFLAKAKEDFLKKWESPAQNTAHLDQFERIKTLGTGSFGRVMLVKHKE 65
Query: 369 TGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDSPWVVSLYYSFQDSQYLYLIMEFLP 428
TG YAMK L K ++ Q+ H E+ +L + P++V L +SF+D+ LY++ME++P
Sbjct: 66 TGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVP 125
Query: 429 GGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKLGFIHRDIKPDNILIDIRGHIKLSD 488
GG++ + L R F+E RFY A+ +L E +H L I+RD+KP+N+LID +G+I+++D
Sbjct: 126 GGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTD 185
Query: 489 FGLS 492
FG +
Sbjct: 186 FGFA 189
Score = 107 bits (266), Expect = 9e-23
Identities = 58/144 (40%), Positives = 86/144 (59%), Gaps = 8/144 (5%)
Query: 572 YSTVGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQ 631
++ GTP+Y+APEI L +GY + DWW+LG ++YE G+PPF ++ P + Y KI++ +
Sbjct: 197 WTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGK- 255
Query: 632 TLQFPDDIHISYEAEDLIRRLL-THSENRLGR-HGGADEIKAHPFFSGVDWNTI--RQVE 687
++FP H S + +DL+R LL R G G ++IK H +F+ DW I R+VE
Sbjct: 256 -VRFPS--HFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVE 312
Query: 688 APYIPKLSSVTDTRFFPTDELENV 711
AP+IPK DT F E E +
Sbjct: 313 APFIPKFKGPGDTSNFDDYEEEEI 336
>ECU01g1320 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 865
Score = 135 bits (340), Expect = 2e-31
Identities = 66/146 (45%), Positives = 97/146 (66%), Gaps = 4/146 (2%)
Query: 346 DFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGS-DS 404
D+ VK + KG +GEV LV+++ KIYAMK + K + + A AE++ + S
Sbjct: 44 DYEIVKNVAKGGYGEVFLVRRE---KIYAMKRVSKELVLKQPHTALFMAEKEAMVDCIGS 100
Query: 405 PWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKL 464
W+V + + QD +YLY +M+F+PGGD M +L + + ED RFY AE + A++ +HKL
Sbjct: 101 EWLVCAHMTMQDEEYLYYLMDFIPGGDFMGLLSKEDVLEEDWVRFYAAEIVAALDELHKL 160
Query: 465 GFIHRDIKPDNILIDIRGHIKLSDFG 490
G+IHRD+KPDN+LI I GH+KL+DFG
Sbjct: 161 GWIHRDLKPDNVLIGIDGHVKLADFG 186
Score = 100 bits (249), Expect = 8e-21
Identities = 50/134 (37%), Positives = 80/134 (59%), Gaps = 12/134 (8%)
Query: 574 TVGTPDYIAPEIFLYQG----YGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNF 629
TVGTPDY++P++ YG++ D+W+LG I+YE + G PF S+T ETYR+I
Sbjct: 201 TVGTPDYVSPDVLCSVNEECEYGEDVDFWTLGVIIYEMIYGTTPFYSDTLMETYRRITRV 260
Query: 630 EQTLQFPDDIHISYEAEDLIRRLLTHSENRLGRHGGADEIKAHPFFSGVDWNTIRQVEAP 689
E F +S E LI L+ + R+ +EIK+H FF GVDW+ +++++ P
Sbjct: 261 E----FGFPFKVSPELTSLIEGLIAAKDRRM----RIEEIKSHAFFEGVDWSRLKELKPP 312
Query: 690 YIPKLSSVTDTRFF 703
++P+++ +DT F
Sbjct: 313 FVPEVNGDSDTSHF 326
>Hs4759052 [T] KOG0603 Ribosomal protein S6 kinase
Length = 809
Score = 135 bits (339), Expect = 3e-31
Identities = 72/156 (46%), Positives = 107/156 (68%), Gaps = 5/156 (3%)
Query: 345 DDFNSVKVIGKGAFGEVRLVQK---KDTGKIYAMKTLLKSEMYNKDQLA-HVKAERDVLA 400
++F +KV+G GA+G+V LV+K DTGK+YAMK L K+ + K + H + ER VL
Sbjct: 47 ENFELLKVLGTGAYGKVFLVRKISGHDTGKLYAMKVLKKATIVQKAKTTEHTRTERQVLE 106
Query: 401 G-SDSPWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIE 459
SP++V+L+Y+FQ L+LI++++ GG+L T L + + FTE + Y+ E +LA+E
Sbjct: 107 HIRQSPFLVTLHYAFQTETKLHLILDYINGGELFTHLSQRERFTEHEVQIYVGEIVLALE 166
Query: 460 VIHKLGFIHRDIKPDNILIDIRGHIKLSDFGLSTGF 495
+HKLG I+RDIK +NIL+D GH+ L+DFGLS F
Sbjct: 167 HLHKLGIIYRDIKLENILLDSNGHVVLTDFGLSKEF 202
Score = 79.7 bits (195), Expect = 2e-14
Identities = 67/225 (29%), Positives = 103/225 (45%), Gaps = 24/225 (10%)
Query: 543 NTMLVDAIHLTMTNRQQMQTWRKSRRLMAYSTVGTPDYIAPEIFLY--QGYGQECDWWSL 600
N +L H+ +T+ + + AYS GT +Y+AP+I G+ + DWWSL
Sbjct: 182 NILLDSNGHVVLTDFGLSKEFVADETERAYSFCGTIEYMAPDIVRGGDSGHDKAVDWWSL 241
Query: 601 GAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQFPDDIHISYEAEDLIRRLLTHS-ENR 659
G +MYE L G PF + + + +I + P +S A+DLI+RLL + R
Sbjct: 242 GVLMYELLTGASPFTVDGEKNSQAEISRRILKSEPPYPQEMSALAKDLIQRLLMKDPKKR 301
Query: 660 LG-RHGGADEIKAHPFFSGVDWNTI--RQVEAPYIPKLSSVTDTRFFPTDELENVPDSPX 716
LG ADEIK H FF ++W+ + ++V AP+ P + D F + E P
Sbjct: 302 LGCGPRDADEIKEHLFFQKINWDDLAAKKVPAPFKPVIRDELDVSNFAEEFTEMDP---- 357
Query: 717 XXXXXXXXXXXXXXXXGVPQSNAKEDLPFIGYTYSRFDYLTRKNA 761
+PQS+ K F GY++ L ++NA
Sbjct: 358 -----------TYSPAALPQSSEK---LFQGYSFVAPSILFKRNA 388
Score = 67.0 bits (162), Expect = 1e-10
Identities = 43/146 (29%), Positives = 74/146 (50%), Gaps = 10/146 (6%)
Query: 351 KVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDS-PWVVS 409
K +G+G+F R K + + +K + +K A+ + E L + P +V
Sbjct: 430 KPLGEGSFSICRKCVHKKSNQALQVKII------SKRMEANTQKEITALKLCEGHPNIVK 483
Query: 410 LYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKLGFIHR 469
L+ F D + +L+ME L GG+L L + + F+E + M + + A+ +H LG +HR
Sbjct: 484 LHEVFHDQLHTFLVMELLNGGELFDALRKKKHFSETEASYIMRKLVSALSHMHDLGVVHR 543
Query: 470 DIKPDNILIDIRG---HIKLSDFGLS 492
D+KP+N+L IK+ DFG +
Sbjct: 544 DLKPENLLFTDENDNLEIKIIDFGFA 569
Score = 49.7 bits (117), Expect = 2e-05
Identities = 30/84 (35%), Positives = 43/84 (50%), Gaps = 7/84 (8%)
Query: 583 PEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSE-------TPQETYRKIMNFEQTLQF 635
PE+ GY + CD WSLG I+Y L G PF S + E +KI + + +
Sbjct: 591 PELLNQNGYDESCDLWSLGVILYTMLSGQVPFQSHDRSLTCTSAVEIMKKIKKGDFSFEG 650
Query: 636 PDDIHISYEAEDLIRRLLTHSENR 659
++S EA+DLI+ LLT N+
Sbjct: 651 EAWKNVSQEAKDLIQGLLTVDPNK 674
>YCR091w [R] KOG0610 Putative serine/threonine protein kinase
Length = 720
Score = 134 bits (338), Expect = 4e-31
Identities = 69/164 (42%), Positives = 108/164 (65%), Gaps = 7/164 (4%)
Query: 347 FNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDSPW 406
F ++++G+G G+V L++++DT +I+A+K L K EM + ++ V E+++LA SD P+
Sbjct: 324 FEKIRLLGQGDVGKVYLMRERDTNQIFALKVLNKHEMIKRKKIKRVLTEQEILATSDHPF 383
Query: 407 VVSLYYSFQDSQYLYLIMEFLPGGDLMTML--IRWQIFTEDVTRFYMAECILAIEVIHKL 464
+V+LY+SFQ YLYL ME+ GG+ L + + E+ +FY +E + A+E +H L
Sbjct: 384 IVTLYHSFQTKDYLYLCMEYCMGGEFFRALQTRKSKCIAEEDAKFYASEVVAALEYLHLL 443
Query: 465 GFIHRDIKPDNILIDIRGHIKLSDFGLS---TGFHK--THDSSY 503
GFI+RD+KP+NIL+ GH+ LSDF LS TG K DS+Y
Sbjct: 444 GFIYRDLKPENILLHQSGHVMLSDFDLSIQATGSKKPTMKDSTY 487
Score = 104 bits (260), Expect = 4e-22
Identities = 55/144 (38%), Positives = 80/144 (55%), Gaps = 3/144 (2%)
Query: 553 TMTNRQQMQTWRKSRRLMAYSTVGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWP 612
TM + + T S S VGT +Y+APE+ G+ DWW+LG ++YE L G
Sbjct: 481 TMKDSTYLDTKICSDGFRTNSFVGTEEYLAPEVIRGNGHTAAVDWWTLGILIYEMLFGCT 540
Query: 613 PFCSETPQETYRKIMNFEQTLQFPDDIHISYEAEDLIRRLLTHSE-NRLGRHGGADEIKA 671
PF + ET+ I+ + ++FP D +S +DLI++LL +E RLG GA +IK
Sbjct: 541 PFKGDNSNETFSNILT--KDVKFPHDKEVSKNCKDLIKKLLNKNEAKRLGSKSGAADIKR 598
Query: 672 HPFFSGVDWNTIRQVEAPYIPKLS 695
HPFF V W+ +R + P IP L+
Sbjct: 599 HPFFKKVQWSFLRNQDPPLIPALN 622
>Hs20070247_2 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 378
Score = 134 bits (337), Expect = 5e-31
Identities = 74/188 (39%), Positives = 113/188 (59%), Gaps = 11/188 (5%)
Query: 305 ELESELASQDWSEERKNRQLASLGKKESQFXXXXXXXXXXDDFNSVKVIGKGAFGEVRLV 364
E E E +SQ +N L G ++ DF+ +KVIGKG+FG+V L
Sbjct: 12 EDEDERSSQKLHSTSQNINLGPSGNPHAK----------PTDFDFLKVIGKGSFGKVLLA 61
Query: 365 QKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGS-DSPWVVSLYYSFQDSQYLYLI 423
++K GK+YA+K L K + N+ + H+ AER+VL + P++V L+YSFQ ++ LY +
Sbjct: 62 KRKLDGKVYAVKVLQKKIVLNRKEQKHIMAERNVLLKNVKHPFLVGLHYSFQTTEKLYFV 121
Query: 424 MEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKLGFIHRDIKPDNILIDIRGH 483
++F+ GG+L L R + F E RFY AE A+ +H + ++RD+KP+NIL+D GH
Sbjct: 122 LDFVNGGELFFHLQRERSFPEHRARFYAAEIASALGYLHSIKIVYRDLKPENILVDSVGH 181
Query: 484 IKLSDFGL 491
+ L+DFGL
Sbjct: 182 VVLTDFGL 189
Score = 84.7 bits (208), Expect = 5e-16
Identities = 47/133 (35%), Positives = 69/133 (51%), Gaps = 7/133 (5%)
Query: 576 GTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQF 635
GTP+Y+APE+ Q Y DWW LGA++YE L G PPF E Y I++ +L+
Sbjct: 205 GTPEYLAPEVIRKQPYDNTVDWWCLGAVLYEMLYGLPPFYCRDVAEMYDNILHKPLSLR- 263
Query: 636 PDDIHISYEAEDLIRRLLTHS-ENRLGRHGGADEIKAHPFFSGVDWNTI--RQVEAPYIP 692
+S A ++ LL +NRLG EI+ HPFF + W + +++ P+ P
Sbjct: 264 ---PGVSLRAWSILEELLEKDRQNRLGAKEDFLEIQNHPFFESLSWADLVQKKIPPPFNP 320
Query: 693 KLSSVTDTRFFPT 705
++ D R F T
Sbjct: 321 NVAGPDDIRNFDT 333
>7297542 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 353
Score = 134 bits (336), Expect = 7e-31
Identities = 62/148 (41%), Positives = 99/148 (66%)
Query: 345 DDFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDS 404
DDF +K +G G+FG V +VQ K T YAMK L K ++ Q+ H E+ +L
Sbjct: 44 DDFERIKTLGTGSFGRVMIVQHKPTKDYYAMKILDKQKVVKLKQVEHTLNEKRILQAIQF 103
Query: 405 PWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKL 464
P++VSL Y F+D+ LY+++E++PGG++ + L + F+E +RFY A+ +LA E +H L
Sbjct: 104 PFLVSLRYHFKDNSNLYMVLEYVPGGEMFSHLRKVGRFSEPHSRFYAAQIVLAFEYLHYL 163
Query: 465 GFIHRDIKPDNILIDIRGHIKLSDFGLS 492
I+RD+KP+N+LID +G++K++DFG +
Sbjct: 164 DLIYRDLKPENLLIDSQGYLKVTDFGFA 191
Score = 98.6 bits (244), Expect = 3e-20
Identities = 53/142 (37%), Positives = 83/142 (58%), Gaps = 8/142 (5%)
Query: 572 YSTVGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQ 631
++ GTP+Y+APEI L +GY + DWW+LG ++YE G+PPF ++ P + Y KI++ +
Sbjct: 199 WTLCGTPEYLAPEIILSKGYNKAVDWWALGVLVYEMAAGYPPFFADQPIQIYEKIVSGK- 257
Query: 632 TLQFPDDIHISYEAEDLIRRLL-THSENRLGR-HGGADEIKAHPFFSGVDWNTI--RQVE 687
++FP H + +DL+R LL R G G ++IK +F+ DW I +++E
Sbjct: 258 -VRFPS--HFGSDLKDLLRNLLQVDLTKRYGNLKAGVNDIKNQKWFASTDWIAIFQKKIE 314
Query: 688 APYIPKLSSVTDTRFFPTDELE 709
AP+IP+ DT F E E
Sbjct: 315 APFIPRCKGPGDTSNFDDYEEE 336
>Hs4502023 [T] KOG0690 Serine/threonine protein kinase
Length = 481
Score = 133 bits (335), Expect = 9e-31
Identities = 65/147 (44%), Positives = 99/147 (67%)
Query: 345 DDFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDS 404
+DF+ +K++GKG FG+V LV++K TG+ YAMK L K + KD++AH E VL +
Sbjct: 150 NDFDYLKLLGKGTFGKVILVREKATGRYYAMKILRKEVIIAKDEVAHTVTESRVLQNTRH 209
Query: 405 PWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKL 464
P++ +L Y+FQ L +ME+ GG+L L R ++FTE+ RFY AE + A+E +H
Sbjct: 210 PFLTALKYAFQTHDRLCFVMEYANGGELFFHLSRERVFTEERARFYGAEIVSALEYLHSR 269
Query: 465 GFIHRDIKPDNILIDIRGHIKLSDFGL 491
++RDIK +N+++D GHIK++DFGL
Sbjct: 270 DVVYRDIKLENLMLDKDGHIKITDFGL 296
Score = 82.0 bits (201), Expect = 3e-15
Identities = 48/134 (35%), Positives = 77/134 (56%), Gaps = 12/134 (8%)
Query: 576 GTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQF 635
GTP+Y+APE+ YG+ DWW LG +MYE + G PF ++ + + I+ E ++F
Sbjct: 312 GTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFELILMEE--IRF 369
Query: 636 PDDIHISYEAEDLIRRLLTHS-ENRLGRHGG---ADEIKAHPFFSGVDWNTI--RQVEAP 689
P +S EA+ L+ LL + RLG GG A E+ H FF ++W + +++ P
Sbjct: 370 PRT--LSPEAKSLLAGLLKKDPKQRLG--GGPSDAKEVMEHRFFLSINWQDVVQKKLLPP 425
Query: 690 YIPKLSSVTDTRFF 703
+ P+++S DTR+F
Sbjct: 426 FKPQVTSEVDTRYF 439
>Hs4506737 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 525
Score = 133 bits (334), Expect = 1e-30
Identities = 69/149 (46%), Positives = 101/149 (67%), Gaps = 4/149 (2%)
Query: 347 FNSVKVIGKGAFGEVRLVQK---KDTGKIYAMKTLLKSEMY-NKDQLAHVKAERDVLAGS 402
F ++V+GKG +G+V V+K +TGKI+AMK L K+ + N AH KAER++L
Sbjct: 91 FELLRVLGKGGYGKVFQVRKVTGANTGKIFAMKVLKKAMIVRNAKDTAHTKAERNILEEV 150
Query: 403 DSPWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIH 462
P++V L Y+FQ LYLI+E+L GG+L L R IF ED FY+AE +A+ +H
Sbjct: 151 KHPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLEREGIFMEDTACFYLAEISMALGHLH 210
Query: 463 KLGFIHRDIKPDNILIDIRGHIKLSDFGL 491
+ G I+RD+KP+NI+++ +GH+KL+DFGL
Sbjct: 211 QKGIIYRDLKPENIMLNHQGHVKLTDFGL 239
Score = 102 bits (253), Expect = 3e-21
Identities = 59/151 (39%), Positives = 90/151 (59%), Gaps = 9/151 (5%)
Query: 570 MAYSTVGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNF 629
+ ++ GT +Y+APEI + G+ + DWWSLGA+MY+ L G PPF E ++T KI+
Sbjct: 249 VTHTFCGTIEYMAPEILMRSGHNRAVDWWSLGALMYDMLTGAPPFTGENRKKTIDKILKC 308
Query: 630 EQTLQFPDDIHISYEAEDLIRRLL-THSENRLGR-HGGADEIKAHPFFSGVDWNTI--RQ 685
+ L P +++ EA DL+++LL ++ +RLG G A E++AHPFF ++W + R+
Sbjct: 309 K--LNLPP--YLTQEARDLLKKLLKRNAASRLGAGPGDAGEVQAHPFFRHINWEELLARK 364
Query: 686 VEAPYIPKLSSVTDTRFFPTDELENVP-DSP 715
VE P+ P L S D F + P DSP
Sbjct: 365 VEPPFKPLLQSEEDVSQFDSKFTRQTPVDSP 395
>CE14798 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 422
Score = 133 bits (334), Expect = 1e-30
Identities = 66/148 (44%), Positives = 104/148 (69%), Gaps = 1/148 (0%)
Query: 345 DDFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGS-D 403
+DF+ + IGKG+FG V V+ K+T KIYAMK L K + K+++ HV AER+VL +
Sbjct: 92 NDFDYLTTIGKGSFGRVYQVRHKETKKIYAMKILSKEHIRKKNEVKHVMAERNVLINNFK 151
Query: 404 SPWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHK 463
P++VSL++SFQ+ + LY +++ L GG+L + L R + F+E +RFY AE A+ +H+
Sbjct: 152 HPFLVSLHFSFQNKEKLYFVLDHLNGGELFSHLQREKHFSESRSRFYAAEIACALGYLHE 211
Query: 464 LGFIHRDIKPDNILIDIRGHIKLSDFGL 491
I+RD+KP+N+L+D +G++ L+DFGL
Sbjct: 212 KNIIYRDLKPENLLLDDKGYLVLTDFGL 239
Score = 101 bits (251), Expect = 5e-21
Identities = 53/128 (41%), Positives = 77/128 (59%), Gaps = 7/128 (5%)
Query: 576 GTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQF 635
GTP+Y+APEI L + Y + DWW LG+++YE + G PPF S+ E Y KI+N L+
Sbjct: 255 GTPEYLAPEIILKKPYDKTVDWWCLGSVLYEMIFGLPPFYSKDHNEMYDKIINQPLRLKH 314
Query: 636 PDDIHISYEAEDLIRRLLTHSEN-RLGRHGGADEIKAHPFFSGVDWNTI--RQVEAPYIP 692
+IS +LI LL + RLG +I+ HPFF VDW+ + R+++AP+IP
Sbjct: 315 ----NISVPCSELITGLLQKDRSKRLGHRNDFRDIRDHPFFLPVDWDKLLNRELKAPFIP 370
Query: 693 KLSSVTDT 700
K+ + DT
Sbjct: 371 KVKNAMDT 378
>CE28744 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 879
Score = 132 bits (333), Expect = 2e-30
Identities = 64/150 (42%), Positives = 105/150 (69%), Gaps = 4/150 (2%)
Query: 346 DFNSVKVIGKGAFGEVRLVQKK---DTGKIYAMKTLLKSEMYNKDQ-LAHVKAERDVLAG 401
DF +K++G+G +G+V V+K+ D G IYAMK + K ++ ++ L H + ER +L
Sbjct: 22 DFERLKLVGEGGYGKVFQVRKQTGEDKGTIYAMKVITKRKVTGTEKDLRHARDERKILET 81
Query: 402 SDSPWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVI 461
+SP++ L+Y+FQ ++ LYL++EFL GG+L T+L R + E+ RFY++E ILAIE +
Sbjct: 82 INSPFLCDLHYAFQTNEKLYLVLEFLHGGELYTLLERKSDWPEEYARFYLSEIILAIEHL 141
Query: 462 HKLGFIHRDIKPDNILIDIRGHIKLSDFGL 491
H ++RD+KPDN+++++ GH+ L+DFGL
Sbjct: 142 HGHDIVYRDLKPDNVMLNLAGHVVLTDFGL 171
Score = 71.2 bits (173), Expect = 5e-12
Identities = 47/164 (28%), Positives = 80/164 (48%), Gaps = 12/164 (7%)
Query: 543 NTMLVDAIHLTMTNRQQMQ-TWRKSRRLMAYSTVGTPDYIAPEIFLYQGYGQECDWWSLG 601
N ML A H+ +T+ + +K + + + GT +Y+APE+ G+ D W+LG
Sbjct: 155 NVMLNLAGHVVLTDFGLCKYKLKKGEKTLTFC--GTHEYMAPEMIRKVGHDHAVDVWALG 212
Query: 602 AIMYECLIGWPPFCSETPQETYRKIMNFEQTLQFPDDIHISYEAEDLIRRLLTHSENRLG 661
+MY+ +G PPF ETP + + I+ + L +S +DLI+R++
Sbjct: 213 ILMYDMFMGGPPFTGETPADKDKSILKGKVRL----PPKLSASGKDLIKRIIKRDPT--- 265
Query: 662 RHGGADEIKAHPFFSGVDWNTI--RQVEAPYIPKLSSVTDTRFF 703
+IK H FF +DW+ + E P+ P L+++ D F
Sbjct: 266 LRITIPDIKEHEFFEEIDWDKLMAHDFEPPFKPTLANLEDVSHF 309
>YKL166c [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 398
Score = 132 bits (331), Expect = 3e-30
Identities = 58/147 (39%), Positives = 97/147 (65%)
Query: 346 DFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDSP 405
DF ++ +G G+FG V L++ G+ YA+KTL K + Q+ H ER +L+ P
Sbjct: 87 DFQILRTLGTGSFGRVHLIRSNHNGRFYALKTLKKHTIVKLKQVEHTNDERRMLSIVSHP 146
Query: 406 WVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKLG 465
+++ ++ +FQDSQ ++++M+++ GG+L ++L + Q F V +FY AE LA+E +H
Sbjct: 147 FIIRMWGTFQDSQQVFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKD 206
Query: 466 FIHRDIKPDNILIDIRGHIKLSDFGLS 492
I+RD+KP+NIL+D GHIK++DFG +
Sbjct: 207 IIYRDLKPENILLDKNGHIKITDFGFA 233
Score = 101 bits (251), Expect = 5e-21
Identities = 51/129 (39%), Positives = 78/129 (59%), Gaps = 8/129 (6%)
Query: 570 MAYSTVGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNF 629
+ Y+ GTPDYIAPE+ + Y + DWWS G ++YE L G+ PF + +TY I+N
Sbjct: 239 VTYTLCGTPDYIAPEVVSTKPYNKSVDWWSFGVLIYEMLAGYTPFYNSNTMKTYENILNA 298
Query: 630 EQTLQFPDDIHISYEAEDLIRRLLTHS-ENRLGR-HGGADEIKAHPFFSGVDWNTI--RQ 685
E L+FP H +A+DL+++L+T RLG G++++K HP+F+ V W + R
Sbjct: 299 E--LKFPPFFH--PDAQDLLKKLITRDLSERLGNLQNGSEDVKNHPWFNEVIWEKLLARY 354
Query: 686 VEAPYIPKL 694
+E PY P +
Sbjct: 355 IETPYEPPI 363
>At3g10540 [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 483
Score = 132 bits (331), Expect = 3e-30
Identities = 63/145 (43%), Positives = 96/145 (65%)
Query: 346 DFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDSP 405
DF K+ G G++ +V +KKD G +YA+K + K + +++ A+VK ER VL + P
Sbjct: 41 DFELGKIYGVGSYSKVVRAKKKDNGTVYALKIMDKKFITKENKTAYVKLERIVLDQLEHP 100
Query: 406 WVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKLG 465
+V L+++FQD+Q LY+ +E GG+L + R +ED RFY AE + A+E IH +G
Sbjct: 101 GIVKLFFTFQDTQSLYMALESCEGGELFDQITRKGRLSEDEARFYSAEVVDALEYIHNMG 160
Query: 466 FIHRDIKPDNILIDIRGHIKLSDFG 490
IHRDIKP+N+L+ + GHIK++DFG
Sbjct: 161 LIHRDIKPENLLLTLDGHIKIADFG 185
Score = 68.9 bits (167), Expect = 3e-11
Identities = 43/121 (35%), Positives = 61/121 (49%), Gaps = 6/121 (4%)
Query: 571 AYSTVGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFE 630
A + VGT Y+ PE+ D W+LG +Y+ L G PF + +++I+
Sbjct: 207 ACTFVGTAAYVPPEVLNSSPATFGNDLWALGCTLYQMLSGTSPFKDASEWLIFQRII--A 264
Query: 631 QTLQFPDDIHISYEAEDLIRRLLTHSENRLGRHG--GADEIKAHPFFSGVDWNTIRQVEA 688
+ ++FP+ H S A DLI RLL +R G G D +K HPFF GVDW +R
Sbjct: 265 RDIKFPN--HFSEAARDLIDRLLDTDPSRRPGAGSEGYDSLKRHPFFKGVDWKNLRSQTP 322
Query: 689 P 689
P
Sbjct: 323 P 323
>YPL203w [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 380
Score = 130 bits (327), Expect = 8e-30
Identities = 63/180 (35%), Positives = 110/180 (61%), Gaps = 2/180 (1%)
Query: 313 QDWSEERKNRQLASLGKKESQFXXXXXXXXXXDDFNSVKVIGKGAFGEVRLVQKKDTGKI 372
Q ++R+++QL L + Q DF ++ +G G+FG V LV+ G+
Sbjct: 38 QQQQQQRQHQQL--LTSQLPQKSLVSKGKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRY 95
Query: 373 YAMKTLLKSEMYNKDQLAHVKAERDVLAGSDSPWVVSLYYSFQDSQYLYLIMEFLPGGDL 432
YA+K L K ++ Q+ H ER +L + P+++ ++ +FQD++ ++++M+++ GG+L
Sbjct: 96 YAIKVLKKQQVVKMKQVEHTNDERRMLKLVEHPFLIRMWGTFQDARNIFMVMDYIEGGEL 155
Query: 433 MTMLIRWQIFTEDVTRFYMAECILAIEVIHKLGFIHRDIKPDNILIDIRGHIKLSDFGLS 492
++L + Q F V +FY AE ILA+E +H I+RD+KP+NIL+D GHIK++DFG +
Sbjct: 156 FSLLRKSQRFPNPVAKFYAAEVILALEYLHAHNIIYRDLKPENILLDRNGHIKITDFGFA 215
Score = 101 bits (251), Expect = 5e-21
Identities = 57/153 (37%), Positives = 89/153 (57%), Gaps = 12/153 (7%)
Query: 565 KSRRLMAYSTVGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYR 624
K + + ++ GTPDYIAPE+ + Y + DWWSLG ++YE L G+ PF TP +TY
Sbjct: 216 KEVQTVTWTLCGTPDYIAPEVITTKPYNKSVDWWSLGVLIYEMLAGYTPFYDTTPMKTYE 275
Query: 625 KIMNFEQTLQFPDDIHISYEAEDLIRRLLTHS-ENRLGR-HGGADEIKAHPFFSGVDWNT 682
KI+ + + +P H + DL+ +L+T R+G G+ +IKAHP+FS V W
Sbjct: 276 KIL--QGKVVYPPYFH--PDVVDLLSKLITADLTRRIGNLQSGSRDIKAHPWFSEVVWER 331
Query: 683 I--RQVEAPYIPKLSS-VTDTRFF---PTDELE 709
+ + +E PY P ++S + DT F P ++L+
Sbjct: 332 LLAKDIETPYEPPITSGIGDTSLFDQYPEEQLD 364
>Hs20127541 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 427
Score = 130 bits (326), Expect = 1e-29
Identities = 66/147 (44%), Positives = 96/147 (64%), Gaps = 1/147 (0%)
Query: 346 DFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGS-DS 404
DF+ +KVIGKG +G+V L ++K G YA+K L K + K + +H+ AER VL +
Sbjct: 94 DFDFLKVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKSILKKKEQSHIMAERSVLLKNVRH 153
Query: 405 PWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKL 464
P++V L YSFQ + LY +++++ GG+L L R + F E RFY AE AI +H L
Sbjct: 154 PFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQRERRFLEPRARFYAAEVASAIGYLHSL 213
Query: 465 GFIHRDIKPDNILIDIRGHIKLSDFGL 491
I+RD+KP+NIL+D +GH+ L+DFGL
Sbjct: 214 NIIYRDLKPENILLDCQGHVVLTDFGL 240
Score = 87.4 bits (215), Expect = 7e-17
Identities = 48/131 (36%), Positives = 75/131 (56%), Gaps = 7/131 (5%)
Query: 576 GTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQF 635
GTP+Y+APE+ + Y + DWW LGA++YE L G PPF S+ + Y I++ Q LQ
Sbjct: 256 GTPEYLAPEVLRKEPYDRAVDWWCLGAVLYEMLHGLPPFYSQDVSQMYENILH--QPLQI 313
Query: 636 PDDIHISYEAEDLIRRLLTHSE-NRLGRHGGADEIKAHPFFSGVDWNTI--RQVEAPYIP 692
P ++ A DL++ LL + RLG EIK H FFS ++W+ + +++ P+ P
Sbjct: 314 PGGRTVA--ACDLLQSLLHKDQRQRLGSKADFLEIKNHVFFSPINWDDLYHKRLTPPFNP 371
Query: 693 KLSSVTDTRFF 703
++ D + F
Sbjct: 372 NVTGPADLKHF 382
>At5g04510 [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 488
Score = 130 bits (326), Expect = 1e-29
Identities = 62/145 (42%), Positives = 95/145 (64%)
Query: 346 DFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDSP 405
DF K+ G G++ +V +KK+TG +YA+K + K + +++ A+VK ER VL + P
Sbjct: 40 DFEFGKIYGVGSYSKVVRAKKKETGTVYALKIMDKKFITKENKTAYVKLERIVLDQLEHP 99
Query: 406 WVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKLG 465
++ LY++FQD+ LY+ +E GG+L + R +ED RFY AE + A+E IH +G
Sbjct: 100 GIIKLYFTFQDTSSLYMALESCEGGELFDQITRKGRLSEDEARFYTAEVVDALEYIHSMG 159
Query: 466 FIHRDIKPDNILIDIRGHIKLSDFG 490
IHRDIKP+N+L+ GHIK++DFG
Sbjct: 160 LIHRDIKPENLLLTSDGHIKIADFG 184
Score = 65.9 bits (159), Expect = 2e-10
Identities = 43/123 (34%), Positives = 62/123 (49%), Gaps = 10/123 (8%)
Query: 571 AYSTVGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFE 630
A + VGT Y+ PE+ D W+LG +Y+ L G PF + +++I+
Sbjct: 206 ACTFVGTAAYVPPEVLNSSPATFGNDLWALGCTLYQMLSGTSPFKDASEWLIFQRII--A 263
Query: 631 QTLQFPDDIHISYEAEDLIRRLLTHSENRLGRHGGADE----IKAHPFFSGVDWNTIRQV 686
+ ++FP+ H S A DLI RLL +R R G E +K HPFF+GVDW +R
Sbjct: 264 RDIKFPN--HFSEAARDLIDRLLDTEPSR--RPGAGSEGYVALKRHPFFNGVDWKNLRSQ 319
Query: 687 EAP 689
P
Sbjct: 320 TPP 322
>Hs4506057 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 351
Score = 129 bits (325), Expect = 1e-29
Identities = 61/148 (41%), Positives = 98/148 (66%)
Query: 345 DDFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDS 404
+DF K +G G+FG V LV+ K T + YAMK L K ++ Q+ H E+ +L +
Sbjct: 42 EDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNF 101
Query: 405 PWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKL 464
P++V L Y+F+D+ LY++ME++PGG++ + L R F+E RFY A+ +L E +H L
Sbjct: 102 PFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSL 161
Query: 465 GFIHRDIKPDNILIDIRGHIKLSDFGLS 492
I+RD+KP+N+LID +G+I+++DFG +
Sbjct: 162 DLIYRDLKPENLLIDHQGYIQVTDFGFA 189
Score = 107 bits (267), Expect = 7e-23
Identities = 58/144 (40%), Positives = 86/144 (59%), Gaps = 8/144 (5%)
Query: 572 YSTVGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQ 631
++ GTP+Y+APEI L +GY + DWW+LG ++YE G+PPF ++ P + Y KI++ +
Sbjct: 197 WTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGK- 255
Query: 632 TLQFPDDIHISYEAEDLIRRLL-THSENRLGR-HGGADEIKAHPFFSGVDWNTI--RQVE 687
++FP H S + +DL+R LL R G G +IK H +F+ DW I R+VE
Sbjct: 256 -VRFPS--HFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQRKVE 312
Query: 688 APYIPKLSSVTDTRFFPTDELENV 711
AP+IPK DT F E E++
Sbjct: 313 APFIPKFRGSGDTSNFDDYEEEDI 336
>CE15612 [T] KOG0690 Serine/threonine protein kinase
Length = 541
Score = 129 bits (323), Expect = 2e-29
Identities = 62/147 (42%), Positives = 97/147 (65%)
Query: 345 DDFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDS 404
+DF+ +KV+GKG FG+V L ++K T K+YA+K L K + ++++AH E VL
Sbjct: 191 EDFDFLKVLGKGTFGKVILCKEKRTQKLYAIKILKKDVIIAREEVAHTLTENRVLQRCKH 250
Query: 405 PWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKL 464
P++ L YSFQ+ YL +M+F GG+L T + + F+E RFY AE +LA+ +H+
Sbjct: 251 PFLTELKYSFQEQHYLCFVMQFANGGELFTHVRKCGTFSEPRARFYGAEIVLALGYLHRC 310
Query: 465 GFIHRDIKPDNILIDIRGHIKLSDFGL 491
++RD+K +N+L+D GHIK++DFGL
Sbjct: 311 DIVYRDMKLENLLLDKDGHIKIADFGL 337
Score = 82.0 bits (201), Expect = 3e-15
Identities = 52/137 (37%), Positives = 73/137 (52%), Gaps = 12/137 (8%)
Query: 576 GTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQF 635
GTP+Y+APE+ YG+ DWW +G +MYE + G PF S+ + + IM + L+F
Sbjct: 353 GTPEYLAPEVLDDHDYGRCVDWWGVGVVMYEMMCGRLPFYSKDHNKLFELIMAGD--LRF 410
Query: 636 PDDIHISYEAEDLIRRLLTHS-ENRLGRHGGAD---EIKAHPFFSGVDWNTI--RQVEAP 689
P +S EA L+ LL RLG GG + EI FF VDW +++E P
Sbjct: 411 PS--KLSQEARTLLTGLLVKDPTQRLG--GGPEDALEICRADFFRTVDWEATYRKEIEPP 466
Query: 690 YIPKLSSVTDTRFFPTD 706
Y P + S TDT +F +
Sbjct: 467 YKPNVQSETDTSYFDNE 483
>Hs4885061 [T] KOG0690 Serine/threonine protein kinase
Length = 480
Score = 128 bits (322), Expect = 3e-29
Identities = 64/148 (43%), Positives = 99/148 (66%), Gaps = 1/148 (0%)
Query: 345 DDFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDS 404
++F +K++GKG FG+V LV++K TG+ YAMK L K + KD++AH E VL S
Sbjct: 148 NEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTENRVLQNSRH 207
Query: 405 PWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIH-K 463
P++ +L YSFQ L +ME+ GG+L L R ++F+ED RFY AE + A++ +H +
Sbjct: 208 PFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVSALDYLHSE 267
Query: 464 LGFIHRDIKPDNILIDIRGHIKLSDFGL 491
++RD+K +N+++D GHIK++DFGL
Sbjct: 268 KNVVYRDLKLENLMLDKDGHIKITDFGL 295
Score = 85.9 bits (211), Expect = 2e-16
Identities = 50/134 (37%), Positives = 79/134 (58%), Gaps = 12/134 (8%)
Query: 576 GTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQF 635
GTP+Y+APE+ YG+ DWW LG +MYE + G PF ++ ++ + I+ E ++F
Sbjct: 311 GTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEE--IRF 368
Query: 636 PDDIHISYEAEDLIRRLLTHS-ENRLGRHGG---ADEIKAHPFFSGVDWNTI--RQVEAP 689
P + EA+ L+ LL + RLG GG A EI H FF+G+ W + +++ P
Sbjct: 369 PRT--LGPEAKSLLSGLLKKDPKQRLG--GGSEDAKEIMQHRFFAGIVWQHVYEKKLSPP 424
Query: 690 YIPKLSSVTDTRFF 703
+ P+++S TDTR+F
Sbjct: 425 FKPQVTSETDTRYF 438
>Hs4506735 [T] KOG0603 Ribosomal protein S6 kinase
Length = 772
Score = 128 bits (321), Expect = 4e-29
Identities = 68/156 (43%), Positives = 104/156 (66%), Gaps = 5/156 (3%)
Query: 345 DDFNSVKVIGKGAFGEVRLVQKK---DTGKIYAMKTLLKSEMYNKDQLA-HVKAERDVLA 400
++F +KV+G GA+G+V LV+K D GK+YAMK L K+ + + + H + ER VL
Sbjct: 31 ENFELLKVLGTGAYGKVFLVRKAGGHDAGKLYAMKVLRKAALVQRAKTQEHTRTERSVLE 90
Query: 401 -GSDSPWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIE 459
+P++V+L+Y+FQ L+LI++++ GG++ T L + Q F E R Y E +LA+E
Sbjct: 91 LVRQAPFLVTLHYAFQTDAKLHLILDYVSGGEMFTHLYQRQYFKEAEVRVYGGEIVLALE 150
Query: 460 VIHKLGFIHRDIKPDNILIDIRGHIKLSDFGLSTGF 495
+HKLG I+RD+K +N+L+D GHI L+DFGLS F
Sbjct: 151 HLHKLGIIYRDLKLENVLLDSEGHIVLTDFGLSKEF 186
Score = 89.4 bits (220), Expect = 2e-17
Identities = 59/180 (32%), Positives = 92/180 (50%), Gaps = 7/180 (3%)
Query: 543 NTMLVDAIHLTMTNRQQMQTWRKSRRLMAYSTVGTPDYIAPEIFLYQ-GYGQECDWWSLG 601
N +L H+ +T+ + + + +S GT +Y+APEI + G+G+ DWWSLG
Sbjct: 166 NVLLDSEGHIVLTDFGLSKEFLTEEKERTFSFCGTIEYMAPEIIRSKTGHGKAVDWWSLG 225
Query: 602 AIMYECLIGWPPFCSETPQETYRKIMNFEQTLQFPDDIHISYEAEDLIRRLLTHS-ENRL 660
+++E L G PF E + T ++ P I A+DL++RLL + RL
Sbjct: 226 ILLFELLTGASPFTLEGERNTQAEVSRRILKCSPPFPPRIGPVAQDLLQRLLCKDPKKRL 285
Query: 661 GR-HGGADEIKAHPFFSGVDWNTI--RQVEAPYIPKLSSVTDTRFFPTD--ELENVPDSP 715
G GA E++ HPFF G+DW + R++ AP+ P++ S D F + LE V P
Sbjct: 286 GAGPQGAQEVRNHPFFQGLDWVALAARKIPAPFRPQIRSELDVGNFAEEFTRLEPVYSPP 345
Score = 62.8 bits (151), Expect = 2e-09
Identities = 43/147 (29%), Positives = 78/147 (52%), Gaps = 15/147 (10%)
Query: 353 IGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLA---GSDSPWVVS 409
+G+G+F R +++ +G+ +A+K L + N +R+V A P VV+
Sbjct: 417 LGQGSFSVCRRCRQRQSGQEFAVKILSRRLEAN--------TQREVAALRLCQSHPNVVN 468
Query: 410 LYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIH-KLGFIH 468
L+ D + YL++E L GG+L+ + + + F+E + + A+ +H + G +H
Sbjct: 469 LHEVHHDQLHTYLVLELLRGGELLEHIRKKRHFSESEASQILRSLVSAVSFMHEEAGVVH 528
Query: 469 RDIKPDNILI--DIRG-HIKLSDFGLS 492
RD+KP+NIL D G +K+ DFG +
Sbjct: 529 RDLKPENILYADDTPGAPVKIIDFGFA 555
Score = 51.6 bits (122), Expect = 4e-06
Identities = 33/85 (38%), Positives = 42/85 (48%), Gaps = 7/85 (8%)
Query: 577 TPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQ-------ETYRKIMNF 629
T Y APE+ QGY + CD WSLG I+Y L G PF + Q E KI
Sbjct: 572 TLQYAAPELLAQQGYDESCDLWSLGVILYMMLSGQVPFQGASGQGGQSQAAEIMCKIREG 631
Query: 630 EQTLQFPDDIHISYEAEDLIRRLLT 654
+L +S EA++L+R LLT
Sbjct: 632 RFSLDGEAWQGVSEEAKELVRGLLT 656
>YJL164c [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 397
Score = 127 bits (320), Expect = 5e-29
Identities = 57/147 (38%), Positives = 97/147 (65%)
Query: 346 DFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDSP 405
+F ++ +G G+FG V L++ + G+ YAMK L K + Q+ H ER +L+ P
Sbjct: 86 NFQILRTLGTGSFGRVHLIRSRHNGRYYAMKVLKKEIVVRLKQVEHTNDERLMLSIVTHP 145
Query: 406 WVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKLG 465
+++ ++ +FQD+Q +++IM+++ GG+L ++L + Q F V +FY AE LA+E +H
Sbjct: 146 FIIRMWGTFQDAQQIFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKD 205
Query: 466 FIHRDIKPDNILIDIRGHIKLSDFGLS 492
I+RD+KP+NIL+D GHIK++DFG +
Sbjct: 206 IIYRDLKPENILLDKNGHIKITDFGFA 232
Score = 98.6 bits (244), Expect = 3e-20
Identities = 51/129 (39%), Positives = 74/129 (56%), Gaps = 8/129 (6%)
Query: 570 MAYSTVGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNF 629
+ Y+ GTPDYIAPE+ + Y + DWWS G ++YE L G+ PF +TY KI+N
Sbjct: 238 VTYTLCGTPDYIAPEVVSTKPYNKSIDWWSFGILIYEMLAGYTPFYDSNTMKTYEKILNA 297
Query: 630 EQTLQFPDDIHISYEAEDLIRRLLTHS-ENRLGR-HGGADEIKAHPFFSGVDWNTI--RQ 685
E L+FP + + +DL+ RL+T RLG G +++K HP+F V W + R
Sbjct: 298 E--LRFPP--FFNEDVKDLLSRLITRDLSQRLGNLQNGTEDVKNHPWFKEVVWEKLLSRN 353
Query: 686 VEAPYIPKL 694
+E PY P +
Sbjct: 354 IETPYEPPI 362
>Hs10835242 [T] KOG0614 cGMP-dependent protein kinase
Length = 686
Score = 127 bits (320), Expect = 5e-29
Identities = 65/155 (41%), Positives = 98/155 (62%), Gaps = 3/155 (1%)
Query: 346 DFNSVKVIGKGAFGEVRLVQ-KKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDS 404
DFN + +G G FG V LVQ K + K +AMK L K + + Q H+++E+ ++ G+ S
Sbjct: 374 DFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQQEHIRSEKQIMQGAHS 433
Query: 405 PWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKL 464
++V LY +F+DS+YLY++ME GG+L T+L F + TRFY A + A +H
Sbjct: 434 DFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLHSK 493
Query: 465 GFIHRDIKPDNILIDIRGHIKLSDFGLS--TGFHK 497
G I+RD+KP+N+++D RG+ KL DFG + GF K
Sbjct: 494 GIIYRDLKPENLILDHRGYAKLVDFGFAKKIGFGK 528
Score = 97.4 bits (241), Expect = 7e-20
Identities = 57/145 (39%), Positives = 81/145 (55%), Gaps = 9/145 (6%)
Query: 576 GTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQF 635
GTP+Y+APEI L +G+ D+WSLG +MYE L G PPF P +TY I+ ++F
Sbjct: 535 GTPEYVAPEIILNKGHDISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEF 594
Query: 636 PDDIHISYEAEDLIRRLL-THSENRLGR-HGGADEIKAHPFFSGVDWNTIRQ--VEAPYI 691
P I+ A +LI++L + RLG G +I+ H +F G +W +R+ + P I
Sbjct: 595 PK--KIAKNAANLIKKLCRDNPSERLGNLKNGVKDIQKHKWFEGFNWEGLRKGTLTPPII 652
Query: 692 PKLSSVTDTR---FFPTDELENVPD 713
P ++S TDT FP D E PD
Sbjct: 653 PSVASPTDTSNFDSFPEDNDEPPPD 677
>CE04603 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 371
Score = 127 bits (320), Expect = 5e-29
Identities = 60/140 (42%), Positives = 91/140 (64%)
Query: 353 IGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDSPWVVSLYY 412
IGKG FG V L + K TG YA+K L + + Q HV E+ VL P++V +Y
Sbjct: 69 IGKGTFGRVELARDKITGAHYALKVLNIRRVVDMRQTQHVHNEKRVLLQLKHPFIVKMYA 128
Query: 413 SFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKLGFIHRDIK 472
S +DS +LY+IMEF+PGG++ + L + F+ + RFY +E + A+E IH LG ++RD+K
Sbjct: 129 SEKDSNHLYMIMEFVPGGEMFSYLRASRSFSNSMARFYASEIVCALEYIHSLGIVYRDLK 188
Query: 473 PDNILIDIRGHIKLSDFGLS 492
P+N+++ GHIK++DFG +
Sbjct: 189 PENLMLSKEGHIKMADFGFA 208
Score = 91.3 bits (225), Expect = 5e-18
Identities = 57/165 (34%), Positives = 87/165 (52%), Gaps = 12/165 (7%)
Query: 543 NTMLVDAIHLTMTNRQQMQTWRKSRRLMAYSTVGTPDYIAPEIFLYQGYGQECDWWSLGA 602
N ML H+ M + + K R Y+ GTPDY+APE G+ + DWW+LG
Sbjct: 191 NLMLSKEGHIKMADFG----FAKELRDRTYTICGTPDYLAPESLARTGHNKGVDWWALGI 246
Query: 603 IMYECLIGWPPFCSETPQETYRKIMNFEQTLQFPDDIHISYEAEDLIRRLL-THSENRLG 661
++YE ++G PPF +T E Y I+ E L+FP +++ A+DL+++LL R+G
Sbjct: 247 LIYEMMVGKPPFRGKTTSEIYDAII--EHKLKFPRSFNLA--AKDLVKKLLEVDRTQRIG 302
Query: 662 -RHGGADEIKAHPFFSGVDWNTI--RQVEAPYIPKLSSVTDTRFF 703
G ++K H +F V+W+ +VE P +P L DT F
Sbjct: 303 CMKNGTQDVKDHKWFEKVNWDDTLHLRVEPPIVPTLYHPGDTGNF 347
>CE17354 [T] KOG0694 Serine/threonine protein kinase
Length = 567
Score = 127 bits (318), Expect = 8e-29
Identities = 65/147 (44%), Positives = 95/147 (64%), Gaps = 1/147 (0%)
Query: 347 FNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLA-GSDSP 405
FN +KV+GKG+FG+V LV+ K + YAMK L K + D ER VL S P
Sbjct: 238 FNLLKVLGKGSFGKVMLVELKGKNEFYAMKCLKKDVILEDDDTECTYIERRVLILASQCP 297
Query: 406 WVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKLG 465
++ L+ SFQ ++YL+ +ME+L GGDLM + + + F E TRFY E ++A++ +H
Sbjct: 298 FLCQLFCSFQTNEYLFFVMEYLNGGDLMHHIQQIKKFDEARTRFYACEIVVALQFLHTNN 357
Query: 466 FIHRDIKPDNILIDIRGHIKLSDFGLS 492
I+RD+K DN+L+D GHIKL+DFG++
Sbjct: 358 IIYRDLKLDNVLLDCDGHIKLADFGMA 384
Score = 87.0 bits (214), Expect = 1e-16
Identities = 59/160 (36%), Positives = 78/160 (47%), Gaps = 8/160 (5%)
Query: 551 HLTMTNRQQMQTWRKSRRLMAYSTVGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIG 610
H+ + + +T MA + GTPDYI+PEI Q Y + D+WS G +MYE L+G
Sbjct: 375 HIKLADFGMAKTEMNRENGMASTFCGTPDYISPEIIKGQLYNEAVDFWSFGVLMYEMLVG 434
Query: 611 WPPFCSETPQETYRKIMNFEQTLQFPDDIHISYEAEDLIRRLLTHSEN-RLGRHGGAD-E 668
PF E E + I+N + FP IS EA + L + N RLG D
Sbjct: 435 QSPFHGEGEDELFDSILN--ERPYFPKT--ISKEAAKCLSALFDRNPNTRLGMPECPDGP 490
Query: 669 IKAHPFFSGVDWNTI--RQVEAPYIPKLSSVTDTRFFPTD 706
I+ H FF GVDW RQV P+ P + S +D F D
Sbjct: 491 IRQHCFFRGVDWKRFENRQVPPPFKPNIKSNSDASNFDDD 530
>CE17353 [T] KOG0694 Serine/threonine protein kinase
Length = 704
Score = 127 bits (318), Expect = 8e-29
Identities = 65/147 (44%), Positives = 95/147 (64%), Gaps = 1/147 (0%)
Query: 347 FNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLA-GSDSP 405
FN +KV+GKG+FG+V LV+ K + YAMK L K + D ER VL S P
Sbjct: 375 FNLLKVLGKGSFGKVMLVELKGKNEFYAMKCLKKDVILEDDDTECTYIERRVLILASQCP 434
Query: 406 WVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKLG 465
++ L+ SFQ ++YL+ +ME+L GGDLM + + + F E TRFY E ++A++ +H
Sbjct: 435 FLCQLFCSFQTNEYLFFVMEYLNGGDLMHHIQQIKKFDEARTRFYACEIVVALQFLHTNN 494
Query: 466 FIHRDIKPDNILIDIRGHIKLSDFGLS 492
I+RD+K DN+L+D GHIKL+DFG++
Sbjct: 495 IIYRDLKLDNVLLDCDGHIKLADFGMA 521
Score = 87.0 bits (214), Expect = 1e-16
Identities = 59/160 (36%), Positives = 78/160 (47%), Gaps = 8/160 (5%)
Query: 551 HLTMTNRQQMQTWRKSRRLMAYSTVGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIG 610
H+ + + +T MA + GTPDYI+PEI Q Y + D+WS G +MYE L+G
Sbjct: 512 HIKLADFGMAKTEMNRENGMASTFCGTPDYISPEIIKGQLYNEAVDFWSFGVLMYEMLVG 571
Query: 611 WPPFCSETPQETYRKIMNFEQTLQFPDDIHISYEAEDLIRRLLTHSEN-RLGRHGGAD-E 668
PF E E + I+N + FP IS EA + L + N RLG D
Sbjct: 572 QSPFHGEGEDELFDSILN--ERPYFPKT--ISKEAAKCLSALFDRNPNTRLGMPECPDGP 627
Query: 669 IKAHPFFSGVDWNTI--RQVEAPYIPKLSSVTDTRFFPTD 706
I+ H FF GVDW RQV P+ P + S +D F D
Sbjct: 628 IRQHCFFRGVDWKRFENRQVPPPFKPNIKSNSDASNFDDD 667
>CE29298 [T] KOG0690 Serine/threonine protein kinase
Length = 483
Score = 126 bits (317), Expect = 1e-28
Identities = 62/147 (42%), Positives = 97/147 (65%)
Query: 345 DDFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDS 404
DDF+ +KV+G+G FG+V L ++K + K+YA+K + K + ++ ++AH E VL
Sbjct: 178 DDFDFLKVLGQGTFGKVILCREKSSDKLYAIKIIRKEMVVDRSEVAHTLTENRVLYACVH 237
Query: 405 PWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKL 464
P++ L YSFQ ++ +MEF GG+L T L R + F+E TRFY +E ILA+ +H
Sbjct: 238 PFLTLLKYSFQAQYHICFVMEFANGGELFTHLQRCKTFSEARTRFYGSEIILALGYLHHR 297
Query: 465 GFIHRDIKPDNILIDIRGHIKLSDFGL 491
++RD+K +N+L+D GHIK++DFGL
Sbjct: 298 NIVYRDMKLENLLLDRDGHIKITDFGL 324
Score = 76.6 bits (187), Expect = 1e-13
Identities = 48/132 (36%), Positives = 69/132 (51%), Gaps = 8/132 (6%)
Query: 576 GTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQF 635
GTP+Y+APE+ Y + DWW +G +MYE + G PF ++ + + I + L+F
Sbjct: 340 GTPEYLAPEVIEDIDYDRSVDWWGVGVVMYEMMCGRLPFSAKENGKLFELITTCD--LKF 397
Query: 636 PDDIHISYEAEDLIRRLLTH-SENRLGR-HGGADEIKAHPFFSGVDWNTI--RQVEAPYI 691
P+ +S EA L+ LL RLG A E+ FF VDW ++VE P+
Sbjct: 398 PN--RLSPEAVTLLSGLLERVPAKRLGAGPDDAREVSRAEFFKDVDWEATLRKEVEPPFK 455
Query: 692 PKLSSVTDTRFF 703
P + S TDT FF
Sbjct: 456 PNVMSETDTSFF 467
>CE18646 [T] KOG0690 Serine/threonine protein kinase
Length = 528
Score = 126 bits (317), Expect = 1e-28
Identities = 62/147 (42%), Positives = 97/147 (65%)
Query: 345 DDFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDS 404
DDF+ +KV+G+G FG+V L ++K + K+YA+K + K + ++ ++AH E VL
Sbjct: 178 DDFDFLKVLGQGTFGKVILCREKSSDKLYAIKIIRKEMVVDRSEVAHTLTENRVLYACVH 237
Query: 405 PWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKL 464
P++ L YSFQ ++ +MEF GG+L T L R + F+E TRFY +E ILA+ +H
Sbjct: 238 PFLTLLKYSFQAQYHICFVMEFANGGELFTHLQRCKTFSEARTRFYGSEIILALGYLHHR 297
Query: 465 GFIHRDIKPDNILIDIRGHIKLSDFGL 491
++RD+K +N+L+D GHIK++DFGL
Sbjct: 298 NIVYRDMKLENLLLDRDGHIKITDFGL 324
Score = 76.6 bits (187), Expect = 1e-13
Identities = 48/132 (36%), Positives = 69/132 (51%), Gaps = 8/132 (6%)
Query: 576 GTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQF 635
GTP+Y+APE+ Y + DWW +G +MYE + G PF ++ + + I + L+F
Sbjct: 340 GTPEYLAPEVIEDIDYDRSVDWWGVGVVMYEMMCGRLPFSAKENGKLFELITTCD--LKF 397
Query: 636 PDDIHISYEAEDLIRRLLTH-SENRLGR-HGGADEIKAHPFFSGVDWNTI--RQVEAPYI 691
P+ +S EA L+ LL RLG A E+ FF VDW ++VE P+
Sbjct: 398 PN--RLSPEAVTLLSGLLERVPAKRLGAGPDDAREVSRAEFFKDVDWEATLRKEVEPPFK 455
Query: 692 PKLSSVTDTRFF 703
P + S TDT FF
Sbjct: 456 PNVMSETDTSFF 467
>CE03492 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 379
Score = 126 bits (317), Expect = 1e-28
Identities = 60/147 (40%), Positives = 96/147 (64%)
Query: 347 FNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDSPW 406
F+ ++ IG+GAFG+V +VQ++ T K +A+K + K K A+V E +L+ P+
Sbjct: 28 FSVIRSIGRGAFGKVCIVQERKTKKYFALKYMNKRRCIEKGVAANVIRELTLLSKMSHPF 87
Query: 407 VVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKLGF 466
+V+L+Y+FQD Y+Y++ + L GGDL L + F ED + Y+ E LA+E +H++
Sbjct: 88 IVNLWYTFQDGDYMYMVSDLLLGGDLRYHLSQQGKFAEDRAKLYLCEICLAVEYLHEMKI 147
Query: 467 IHRDIKPDNILIDIRGHIKLSDFGLST 493
+HRDIKP+NIL+D +GH L+D L+T
Sbjct: 148 VHRDIKPENILLDEQGHAHLTDLNLAT 174
Score = 52.0 bits (123), Expect = 3e-06
Identities = 38/122 (31%), Positives = 58/122 (47%), Gaps = 14/122 (11%)
Query: 570 MAYSTVGTPDYIAPEIF-----LYQGYGQECDWWSLGAIMYECLIGWPP--FCSET-PQE 621
+A S GT Y+APEI+ + GY DWW+LG YE L G P F S T P+E
Sbjct: 181 LATSYSGTRPYMAPEIYATYLEIEDGYDSRVDWWALGVCFYEMLRGRTPFEFSSRTKPEE 240
Query: 622 TYRKIMNFEQTLQFPDDIHISYEAEDLIRRLLTHSENRLGRHGGADEIKAHPFFSGVDWN 681
Y + E ++ +P H + I +L + + R G + IK H + +D+
Sbjct: 241 AY--VAFRESSIPYP--AHWPTDLIQFINSMLKFDKEK--RLVGLEAIKKHSYTERIDFK 294
Query: 682 TI 683
++
Sbjct: 295 SV 296
>SPBC1861.09 [R] KOG0610 Putative serine/threonine protein kinase
Length = 526
Score = 126 bits (316), Expect = 1e-28
Identities = 64/148 (43%), Positives = 95/148 (63%), Gaps = 2/148 (1%)
Query: 347 FNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDSPW 406
F ++++G+G G+V LV++K +++AMK L K EM + ++ V AE+++L S P+
Sbjct: 155 FEKIRLLGQGDVGKVYLVRQKSNHRLFAMKILNKREMIKRHKVNRVLAEQEILTKSKHPF 214
Query: 407 VVSLYYSFQDSQYLYLIMEFLPGGDLMTML--IRWQIFTEDVTRFYMAECILAIEVIHKL 464
+V+LY+SFQ YLYL ME+ GG+ L + I E FY AE A+E +H +
Sbjct: 215 IVTLYHSFQSRDYLYLCMEYCAGGEFFRALHSLPKHILPEKDACFYAAEVTAALEYLHLM 274
Query: 465 GFIHRDIKPDNILIDIRGHIKLSDFGLS 492
GFI+RD+KP+NIL+ GHI LSDF LS
Sbjct: 275 GFIYRDLKPENILLHQSGHIMLSDFDLS 302
Score = 89.4 bits (220), Expect = 2e-17
Identities = 47/124 (37%), Positives = 69/124 (54%), Gaps = 2/124 (1%)
Query: 573 STVGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQT 632
S VGT +YIAPE+ G+ DWW+LG +YE L G PF + T+ I+ + +
Sbjct: 341 SFVGTEEYIAPEVIRSCGHTVAVDWWTLGIFIYEILYGTTPFKGKNRHATFSNILYSDVS 400
Query: 633 L-QFPDDIHISYEAEDLIRRLLTHSEN-RLGRHGGADEIKAHPFFSGVDWNTIRQVEAPY 690
++ ++S + LIRRLL E+ R G GA +IK HPFF + W +R ++ P
Sbjct: 401 FPEYHGAPNVSSTCKSLIRRLLVKDESKRCGSVAGASDIKQHPFFRHIQWALLRSMKPPI 460
Query: 691 IPKL 694
IPK+
Sbjct: 461 IPKI 464
>Hs5032091 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 431
Score = 125 bits (313), Expect = 3e-28
Identities = 63/147 (42%), Positives = 96/147 (64%), Gaps = 1/147 (0%)
Query: 346 DFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGS-DS 404
DF+ +KVIGKG+FG+V L + K YA+K L K + K + H+ +ER+VL +
Sbjct: 97 DFHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKH 156
Query: 405 PWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKL 464
P++V L++SFQ + LY +++++ GG+L L R + F E RFY AE A+ +H L
Sbjct: 157 PFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSL 216
Query: 465 GFIHRDIKPDNILIDIRGHIKLSDFGL 491
++RD+KP+NIL+D +GHI L+DFGL
Sbjct: 217 NIVYRDLKPENILLDSQGHIVLTDFGL 243
Score = 90.5 bits (223), Expect = 9e-18
Identities = 55/143 (38%), Positives = 78/143 (54%), Gaps = 8/143 (5%)
Query: 576 GTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQF 635
GTP+Y+APE+ Q Y + DWW LGA++YE L G PPF S E Y I+N + LQ
Sbjct: 259 GTPEYLAPEVLHKQPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILN--KPLQL 316
Query: 636 PDDIHISYEAEDLIRRLLTHSE-NRLGRHGGADEIKAHPFFSGVDWNTI--RQVEAPYIP 692
+I+ A L+ LL RLG EIK+H FFS ++W+ + +++ P+ P
Sbjct: 317 KP--NITNSARHLLEGLLQKDRTKRLGAKDDFMEIKSHVFFSLINWDDLINKKITPPFNP 374
Query: 693 KLSSVTDTRFF-PTDELENVPDS 714
+S + R F P E VP+S
Sbjct: 375 NVSGPNELRHFDPEFTEEPVPNS 397
>CE28739 [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 632
Score = 124 bits (310), Expect = 7e-28
Identities = 89/357 (24%), Positives = 148/357 (40%), Gaps = 49/357 (13%)
Query: 345 DDFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDS 404
+DF ++ +G+GA+ +V ++ T ++A+K L KS + ++ + E+++L
Sbjct: 67 NDFMFLQSMGEGAYSQVFRCREVATDAMFAVKVLQKSYLNRHQKMDAIIREKNILTYLSQ 126
Query: 405 -----PWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIE 459
P+V LY F D +Y ++ + GDL L + F ++F+ +E + ++
Sbjct: 127 ECGGHPFVTQLYTHFHDQARIYFVIGLVENGDLGESLCHFGSFDMLTSKFFASEILTGLQ 186
Query: 460 VIHKLGFIHRDIKPDNILIDIRGHIKLSDFGLSTGFHKTHDSSYYXXXXXXXXXXXXXXX 519
+H +HRD+KPDN+LI GHI ++DFG + F S
Sbjct: 187 FLHDNKIVHRDMKPDNVLIQKDGHILITDFGSAQAFGGLQLSQ----EGFTDANQASSRS 242
Query: 520 XXXXXXXXXXXXXXPNETNNGNRNTMLVDAIHLTMTNRQQMQTWRKSRRLMAYSTVGTPD 579
E N R T VGT
Sbjct: 243 SDSGSPPPTRFYSDEEEENTARRTTF-----------------------------VGTAL 273
Query: 580 YIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQFPDDI 639
Y++PE+ G + D W LG I+++CL G PPF + ++I E FP+
Sbjct: 274 YVSPEMLADGDVGPQTDIWGLGCILFQCLAGQPPFRAVNQYHLLKRIQ--ELDFSFPEG- 330
Query: 640 HISYEAEDLIRRLLTHSENRLGRHGGADEIKAHPFFSGVDWNTIRQVEAP----YIP 692
EA ++I ++L + + E+ AH FF VDW I ++ P YIP
Sbjct: 331 -FPEEASEIIAKILVRDPS---TRITSQELMAHKFFENVDWVNIANIKPPVLHAYIP 383
>SPBC106.10 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 512
Score = 123 bits (309), Expect = 9e-28
Identities = 57/147 (38%), Positives = 95/147 (63%)
Query: 346 DFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDSP 405
DFN ++ +G G+FG V LVQ YA+K L K ++ + Q+ H ER +L+ P
Sbjct: 200 DFNFLQTLGTGSFGRVHLVQSNHNRLYYAIKVLEKKKIVDMKQIEHTCDERYILSRVQHP 259
Query: 406 WVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKLG 465
++ L+ +FQD++ L+++M+F GG+L ++L + F E V +FY AE ILA++ +H
Sbjct: 260 FITILWGTFQDAKNLFMVMDFAEGGELFSLLRKCHRFPEKVAKFYAAEVILALDYLHHNQ 319
Query: 466 FIHRDIKPDNILIDIRGHIKLSDFGLS 492
++RD+KP+N+L+D GH+K+ DFG +
Sbjct: 320 IVYRDLKPENLLLDRFGHLKIVDFGFA 346
Score = 90.1 bits (222), Expect = 1e-17
Identities = 48/125 (38%), Positives = 72/125 (57%), Gaps = 8/125 (6%)
Query: 576 GTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQF 635
GTPDY+APEI + Y + DWWSLG +++E L G+PPF SE P + Y I+ E + +
Sbjct: 359 GTPDYLAPEIISLKPYNKAADWWSLGILIFEMLAGYPPFYSENPMKLYENIL--EGKVNY 416
Query: 636 PDDIHISYEAEDLIRRLLTHSEN-RLGR-HGGADEIKAHPFFSGVDWNTI--RQVEAPYI 691
P + S + DL+ LL R G G+ +I HP+F + W+ I R++E PY+
Sbjct: 417 PS--YFSPASIDLLSHLLQRDITCRYGNLKDGSMDIIMHPWFRDISWDKILTRKIEVPYV 474
Query: 692 PKLSS 696
P + +
Sbjct: 475 PPIQA 479
>7301734 [T] KOG0694 Serine/threonine protein kinase
Length = 739
Score = 123 bits (309), Expect = 9e-28
Identities = 62/147 (42%), Positives = 94/147 (63%), Gaps = 1/147 (0%)
Query: 346 DFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLA-GSDS 404
DFN +KV+GKG+FG+V L +KK T +IYA+K L K + D + E+ +LA ++
Sbjct: 407 DFNFIKVLGKGSFGKVMLAEKKGTDEIYAIKVLKKDAIIQDDDVDCTMTEKRILALAANH 466
Query: 405 PWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKL 464
P++ +L+ FQ L+ +ME++ GGDLM + + + F FY AE LA++ +H
Sbjct: 467 PFLTALHSCFQTPDRLFFVMEYVNGGDLMFQIQKARRFEASRAAFYAAEVTLALQFLHTH 526
Query: 465 GFIHRDIKPDNILIDIRGHIKLSDFGL 491
G I+RD+K DNIL+D GH KL+DFG+
Sbjct: 527 GVIYRDLKLDNILLDQEGHCKLADFGM 553
Score = 102 bits (255), Expect = 2e-21
Identities = 54/140 (38%), Positives = 81/140 (57%), Gaps = 7/140 (5%)
Query: 576 GTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQF 635
GTPDYIAPEI Q YG DWW+LG +MYE + G PPF ++ E + IM+ + +
Sbjct: 569 GTPDYIAPEILKEQEYGASVDWWALGVLMYEMMAGQPPFEADNEDELFDSIMH--DDVLY 626
Query: 636 PDDIHISYEAEDLIRRLLT-HSENRLGRHGGADEIKAHPFFSGVDWNTI--RQVEAPYIP 692
P + +S EA +++ LT + E RLG G +EI+ HPFF+ +DW + R ++ P+ P
Sbjct: 627 P--VWLSREAVSILKGFLTKNPEQRLGCTGDENEIRKHPFFAKLDWKELEKRNIKPPFRP 684
Query: 693 KLSSVTDTRFFPTDELENVP 712
K+ + D F + + P
Sbjct: 685 KMKNPRDANNFDAEFTKEDP 704
>CE05507 [T] KOG0603 Ribosomal protein S6 kinase
Length = 785
Score = 123 bits (308), Expect = 1e-27
Identities = 68/156 (43%), Positives = 104/156 (66%), Gaps = 5/156 (3%)
Query: 345 DDFNSVKVIGKGAFGEVRLVQK---KDTGKIYAMKTLLKSEMYNKDQ-LAHVKAERDVLA 400
++F ++V+GKGA+G+V LV+K KD IYAMK L K+ + K + L H AER VL
Sbjct: 15 ENFALLRVLGKGAYGKVFLVRKVGGKDHNTIYAMKVLRKTRVLTKQKTLEHTMAERQVLE 74
Query: 401 G-SDSPWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIE 459
+P++V+L+Y+FQ L+++ME++ GG+L T L F + RF +AE ++AI+
Sbjct: 75 RLRGTPFLVNLFYAFQTDTKLHIVMEYVRGGELFTHLCSRGHFDLEAARFVIAELVVAID 134
Query: 460 VIHKLGFIHRDIKPDNILIDIRGHIKLSDFGLSTGF 495
+H+ I+RD+K +NIL+D GH+KL+DFGLS F
Sbjct: 135 SLHQRKVIYRDLKLENILLDEEGHVKLTDFGLSKLF 170
Score = 84.3 bits (207), Expect = 6e-16
Identities = 76/320 (23%), Positives = 136/320 (41%), Gaps = 63/320 (19%)
Query: 346 DFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDSP 405
D + ++GKGAF VR ++ G +A+K + + + A + +++ G P
Sbjct: 381 DKSDAGLLGKGAFSVVRRCERVVDGAQFAVKIVSQKFASQAQREARIL---EMVQGH--P 435
Query: 406 WVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKLG 465
+V L+ D + YL+ME L G +L+ + + + FTE M + + A++ +H
Sbjct: 436 NIVQLHDVHSDPLHFYLVMEILTGNELLERIRKLERFTESEAADIMRQLVSAVKYLHDKR 495
Query: 466 FIHRDIKPDNIL---IDIRGHIKLSDFGLSTGFHKTHDSSYYXXXXXXXXXXXXXXXXXX 522
+HRD+KP+NIL ID ++L DF GF +
Sbjct: 496 IVHRDLKPENILFESIDSSARLRLVDF----GFARL------------------------ 527
Query: 523 XXXXXXXXXXXPNETNNGNRNTMLVDAIHLTMTNRQQMQTWRKSRRLMAYSTVGTPDYIA 582
PN ++ ++ ++ + + + + + T Y A
Sbjct: 528 ----------LPNSMEQQLKSVQVLRKMYGLIAHNHSLHS---------ETPCFTLQYAA 568
Query: 583 PEIF----LYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMN--FEQTLQFP 636
PE+ Y ++CD WSLG +++ L G PF + + QE+ +IM F
Sbjct: 569 PEVLDVGDSQPEYNEQCDLWSLGVVLFTMLSGQVPFHARSRQESATEIMQRICRAEFSFT 628
Query: 637 DD--IHISYEAEDLIRRLLT 654
D ++S +A++LI LLT
Sbjct: 629 GDAWTNVSADAKNLITGLLT 648
Score = 84.0 bits (206), Expect = 8e-16
Identities = 55/175 (31%), Positives = 84/175 (47%), Gaps = 6/175 (3%)
Query: 543 NTMLVDAIHLTMTNRQQMQTWRKSRRLMAYSTVGTPDYIAPEIFLYQ--GYGQECDWWSL 600
N +L + H+ +T+ + + A S GT +Y++PE+ GY DWWSL
Sbjct: 150 NILLDEEGHVKLTDFGLSKLFLPGELDRANSYCGTIEYMSPEVINRPEGGYSDVVDWWSL 209
Query: 601 GAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQFPDDIHISYEAEDLIRRLLTHS-ENR 659
G I +E L G PF + Q + + I T + P + +A D I +LL E R
Sbjct: 210 GVISFELLTGCSPFTVDGAQNSSKDIAKRIMTKKVPFPKTMDVDARDFIGQLLEKKLEKR 269
Query: 660 LGRHGGADEIKAHPFFSGVDWNTI--RQVEAPYIPKLSSVTDTRFFPTDELENVP 712
LG + G DEIK H F S +DW+ R ++ +P++ DT+FF + P
Sbjct: 270 LG-YNGVDEIKNHKFMSSIDWDAAVKRTLKPVIVPRIGHDLDTQFFSAEFTSQPP 323
>Hs4885563 [T] KOG0694 Serine/threonine protein kinase
Length = 737
Score = 122 bits (307), Expect = 2e-27
Identities = 62/148 (41%), Positives = 92/148 (61%), Gaps = 1/148 (0%)
Query: 345 DDFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLA-GSD 403
D+FN +KV+GKG+FG+V L + K ++YA+K L K + D + E+ +LA
Sbjct: 406 DEFNFIKVLGKGSFGKVMLAELKGKDEVYAVKVLKKDVILQDDDVDCTMTEKRILALARK 465
Query: 404 SPWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHK 463
P++ LY FQ L+ +ME++ GGDLM + R + F E +RFY AE A+ +H+
Sbjct: 466 HPYLTQLYCCFQTKDRLFFVMEYVNGGDLMFQIQRSRKFDEPRSRFYAAEVTSALMFLHQ 525
Query: 464 LGFIHRDIKPDNILIDIRGHIKLSDFGL 491
G I+RD+K DNIL+D GH KL+DFG+
Sbjct: 526 HGVIYRDLKLDNILLDAEGHCKLADFGM 553
Score = 92.8 bits (229), Expect = 2e-18
Identities = 50/143 (34%), Positives = 76/143 (52%), Gaps = 10/143 (6%)
Query: 576 GTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQF 635
GTPDYIAPEI YG DWW+LG +MYE + G PPF ++ + + I++ + +
Sbjct: 569 GTPDYIAPEILQELEYGPSVDWWALGVLMYEMMAGQPPFEADNEDDLFESILH--DDVLY 626
Query: 636 PDDIHISYEAEDLIRRLLT-HSENRLG---RHGGADEIKAHPFFSGVDWNTIRQ--VEAP 689
P + +S EA +++ +T + RLG G D IK HPFF +DW + Q ++ P
Sbjct: 627 P--VWLSKEAVSILKAFMTKNPHKRLGCVASQNGEDAIKQHPFFKEIDWVLLEQKKIKPP 684
Query: 690 YIPKLSSVTDTRFFPTDELENVP 712
+ P++ + D F D P
Sbjct: 685 FKPRIKTKRDVNNFDQDFTREEP 707
>CE29092 [T] KOG0694 Serine/threonine protein kinase
Length = 707
Score = 122 bits (307), Expect = 2e-27
Identities = 63/161 (39%), Positives = 102/161 (63%), Gaps = 2/161 (1%)
Query: 346 DFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLA-GSDS 404
DF +KV+GKG+FG+V L ++K T ++YA+K L K + D + E+ +L+ +
Sbjct: 377 DFTFMKVLGKGSFGKVMLAERKGTDEVYAIKILKKDVIVQDDDVECTMCEKRILSLAAKH 436
Query: 405 PWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKL 464
P++ +L+ SFQ S L+ +ME++ GGDLM + R + F E RFY AE A++ +H+
Sbjct: 437 PFLTALHSSFQTSDRLFFVMEYVNGGDLMFQIQRARKFDESRARFYAAEVTCALQFLHRN 496
Query: 465 GFIHRDIKPDNILIDIRGHIKLSDFGL-STGFHKTHDSSYY 504
I+RD+K DNIL+D GH +L+DFG+ G +K + +S +
Sbjct: 497 DVIYRDLKLDNILLDAEGHCRLADFGMCKEGINKDNLTSTF 537
Score = 105 bits (262), Expect = 3e-22
Identities = 56/143 (39%), Positives = 84/143 (58%), Gaps = 10/143 (6%)
Query: 576 GTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQF 635
GTPDYIAPEI YG DWW+LG +MYE + G PPF ++ + + I+N + +
Sbjct: 539 GTPDYIAPEILQEMEYGVSVDWWALGVLMYEMMAGQPPFEADNEDDLFEAILN--DDVLY 596
Query: 636 PDDIHISYEAEDLIRRLLT-HSENRLG---RHGGADEIKAHPFFSGVDWNTI--RQVEAP 689
P + +S EA ++++ +T ++ RLG GG D I+AHPFF +DW+ + RQV+ P
Sbjct: 597 P--VWLSKEAVNILKAFMTKNAGKRLGCVVSQGGEDAIRAHPFFREIDWDALESRQVKPP 654
Query: 690 YIPKLSSVTDTRFFPTDELENVP 712
+ PK+ S D F +D + P
Sbjct: 655 FKPKIKSKRDANNFDSDFTKEEP 677
>CE28740 [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 636
Score = 122 bits (307), Expect = 2e-27
Identities = 89/357 (24%), Positives = 148/357 (40%), Gaps = 47/357 (13%)
Query: 345 DDFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDS 404
+DF ++ +G+GA+ +V ++ T ++A+K L KS + ++ + E+++L
Sbjct: 67 NDFMFLQSMGEGAYSQVFRCREVATDAMFAVKVLQKSYLNRHQKMDAIIREKNILTYLSQ 126
Query: 405 -----PWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIE 459
P+V LY F D +Y ++ + GDL L + F ++F+ +E + ++
Sbjct: 127 ECGGHPFVTQLYTHFHDQARIYFVIGLVENGDLGESLCHFGSFDMLTSKFFASEILTGLQ 186
Query: 460 VIHKLGFIHRDIKPDNILIDIRGHIKLSDFGLSTGFHKTHDSSYYXXXXXXXXXXXXXXX 519
+H +HRD+KPDN+LI GHI ++DFG + F S
Sbjct: 187 FLHDNKIVHRDMKPDNVLIQKDGHILITDFGSAQAFGGLQLSQ--EGFTDANQASSRSSD 244
Query: 520 XXXXXXXXXXXXXXPNETNNGNRNTMLVDAIHLTMTNRQQMQTWRKSRRLMAYSTVGTPD 579
E N R T VGT
Sbjct: 245 SGSPPPTRFYSDEEVPEENTARRTTF-----------------------------VGTAL 275
Query: 580 YIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQFPDDI 639
Y++PE+ G + D W LG I+++CL G PPF + ++I E FP+
Sbjct: 276 YVSPEMLADGDVGPQTDIWGLGCILFQCLAGQPPFRAVNQYHLLKRIQ--ELDFSFPEG- 332
Query: 640 HISYEAEDLIRRLLTHSENRLGRHGGADEIKAHPFFSGVDWNTIRQVEAP----YIP 692
EA ++I ++L + + E+ AH FF VDW I ++ P YIP
Sbjct: 333 -FPEEASEIIAKILVRDPS---TRITSQELMAHKFFENVDWVNIANIKPPVLHAYIP 385
>Hs7019489 [T] KOG0694 Serine/threonine protein kinase
Length = 889
Score = 122 bits (305), Expect = 3e-27
Identities = 62/149 (41%), Positives = 97/149 (64%), Gaps = 4/149 (2%)
Query: 346 DFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAG---S 402
DF + V+G+G FG+V LVQ K TGK YA+K L K E+ ++D++ + E+ +L +
Sbjct: 558 DFRCLAVLGRGHFGKVLLVQFKGTGKYYAIKALKKQEVLSRDEIESLYCEKRILEAVGCT 617
Query: 403 DSPWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIH 462
P+++SL FQ S + + EF+PGGDLM M I +F E RFY+A +L ++ +H
Sbjct: 618 GHPFLLSLLVCFQTSSHARFVTEFVPGGDLM-MQIHEDVFPEPQARFYVACVVLGLQFLH 676
Query: 463 KLGFIHRDIKPDNILIDIRGHIKLSDFGL 491
+ I+RD+K DN+L+D +G +K++DFGL
Sbjct: 677 EKKIIYRDLKLDNLLLDAQGFLKIADFGL 705
Score = 90.5 bits (223), Expect = 9e-18
Identities = 47/132 (35%), Positives = 74/132 (55%), Gaps = 8/132 (6%)
Query: 576 GTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQF 635
GTP+++APE+ + Y Q DWW+LG ++YE L+G PF +T +E + I+N +
Sbjct: 721 GTPEFLAPEVLTQEAYTQAVDWWALGVLLYEMLVGECPFPGDTEEEVFDCIVNMDA---- 776
Query: 636 PDDIHISYEAEDLIRRLLTH-SENRLGR-HGGADEIKAHPFFSGVDWNTI--RQVEAPYI 691
P +S + + I++LL E RLG A+EIK PFF +W + R ++ P++
Sbjct: 777 PYPGFLSVQGLEFIQKLLQKCPEKRLGAGEQDAEEIKVQPFFRTTNWQALLARTIQPPFV 836
Query: 692 PKLSSVTDTRFF 703
P L D R+F
Sbjct: 837 PTLCGPADLRYF 848
>7302861 [T] KOG0696 Serine/threonine protein kinase
Length = 700
Score = 121 bits (304), Expect = 3e-27
Identities = 64/148 (43%), Positives = 94/148 (63%), Gaps = 1/148 (0%)
Query: 346 DFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDSP 405
DFN VKVIGKG+FG+V L +++ T ++YA+K L K + D + E+ +LA S P
Sbjct: 370 DFNFVKVIGKGSFGKVLLAERRGTDELYAVKVLRKDVIIQTDDMELPMNEKKILALSGRP 429
Query: 406 -WVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKL 464
++VS++ FQ L+ +ME+ GGDLM + ++ F E V FY E +A+ +H+
Sbjct: 430 PFLVSMHSCFQTMDRLFFVMEYCKGGDLMYHMQQYGRFKESVAIFYAVEVAIALFFLHER 489
Query: 465 GFIHRDIKPDNILIDIRGHIKLSDFGLS 492
I+RD+K DNIL+D GH+KL DFGLS
Sbjct: 490 DIIYRDLKLDNILLDGEGHVKLVDFGLS 517
Score = 80.5 bits (197), Expect = 9e-15
Identities = 50/132 (37%), Positives = 65/132 (48%), Gaps = 8/132 (6%)
Query: 576 GTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQF 635
GTP+Y+APEI Y Y DWWS G +++E + G PF + +R I ++ F
Sbjct: 532 GTPNYMAPEIVSYDPYSIAADWWSFGVLLFEFMAGQAPFEGDDETTVFRNIK--DKKAVF 589
Query: 636 PDDIHISYEAEDLIRRLLTHS-ENRLGRHGGA-DEIKAHPFFSGVDWNTIR--QVEAPYI 691
P H S EA D+I LT NRLG A EI HPFF VDW+ ++E P
Sbjct: 590 PK--HFSVEAMDIITSFLTKKPNNRLGAGRYARQEITTHPFFRNVDWDKAEACEMEPPIK 647
Query: 692 PKLSSVTDTRFF 703
P + D F
Sbjct: 648 PMIKHRKDISNF 659
>7301971 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 356
Score = 121 bits (303), Expect = 5e-27
Identities = 56/148 (37%), Positives = 96/148 (64%)
Query: 345 DDFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDS 404
DD+ +G G+FG+V+LV+++++G YA K L K ++ Q++HV +E++VL
Sbjct: 45 DDYEIKATLGSGSFGKVQLVRERESGVYYASKQLSKDQIVKTKQVSHVMSEKNVLRSMTF 104
Query: 405 PWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKL 464
P V+L S++D LYL++ + GG+L T + + FTE RFY A+ LA+E +H
Sbjct: 105 PNTVNLIASYKDFDSLYLVLPLIGGGELFTYHRKVRKFTEKQARFYAAQVFLALEYLHHC 164
Query: 465 GFIHRDIKPDNILIDIRGHIKLSDFGLS 492
++RD+KP+NI++D G++K++DFG +
Sbjct: 165 SLLYRDLKPENIMMDKNGYLKVTDFGFA 192
Score = 65.9 bits (159), Expect = 2e-10
Identities = 46/146 (31%), Positives = 67/146 (45%), Gaps = 15/146 (10%)
Query: 576 GTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSET--PQETYRKIMNFEQTL 633
GTP+Y+ PEI + YG DWW+ G +++E + G PF + Y KI E
Sbjct: 204 GTPEYLPPEIIQSKPYGTSVDWWAFGVLVFEFVAGHSPFSAHNRDVMSMYNKIC--EADY 261
Query: 634 QFPDDIHISYEAEDLIRRLL-THSENRLGR-HGGADEIKAHPFFSGVDWNTI--RQVEAP 689
+ P + S L+ LL R G G +IK H +F V+W + + V AP
Sbjct: 262 KMPS--YFSGALRHLVDHLLQVDLSKRFGNLINGNRDIKEHEWFKDVEWIPLLNQTVNAP 319
Query: 690 YIPKLSSVTDTRFFPTDELENVPDSP 715
Y+P +S+ D F + V D P
Sbjct: 320 YVPNISNPEDISNF-----DKVSDKP 340
>Hs4826948 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 358
Score = 120 bits (301), Expect = 8e-27
Identities = 56/147 (38%), Positives = 92/147 (62%)
Query: 346 DFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDSP 405
DF+++ +G G FG V LV++K +A+K + ++ Q HV E+ VL P
Sbjct: 48 DFDTLATVGTGTFGRVHLVKEKTAKHFFALKVMSIPDVIRLKQEQHVHNEKSVLKEVSHP 107
Query: 406 WVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKLG 465
+++ L++++ D ++LY++ME++PGG+L + L F+ FY AE I AIE +H
Sbjct: 108 FLIRLFWTWHDERFLYMLMEYVPGGELFSYLRNRGRFSSTTGLFYSAEIICAIEYLHSKE 167
Query: 466 FIHRDIKPDNILIDIRGHIKLSDFGLS 492
++RD+KP+NIL+D GHIKL+DFG +
Sbjct: 168 IVYRDLKPENILLDRDGHIKLTDFGFA 194
Score = 101 bits (251), Expect = 5e-21
Identities = 51/138 (36%), Positives = 84/138 (59%), Gaps = 8/138 (5%)
Query: 572 YSTVGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQ 631
++ GTP+Y+APE+ +G+G+ DWW+LG +++E L G+PPF + P Y+KI+
Sbjct: 202 WTLCGTPEYLAPEVIQSKGHGRAVDWWALGILIFEMLSGFPPFFDDNPFGIYQKIL--AG 259
Query: 632 TLQFPDDIHISYEAEDLIRRLL-THSENRLGR-HGGADEIKAHPFFSGVDWNTI--RQVE 687
+ FP H+ + +DLI++LL RLG GA+++K H +F VDW + R+++
Sbjct: 260 KIDFPR--HLDFHVKDLIKKLLVVDRTRRLGNMKNGANDVKHHRWFRSVDWEAVPQRKLK 317
Query: 688 APYIPKLSSVTDTRFFPT 705
P +PK++ DT F T
Sbjct: 318 PPIVPKIAGDGDTSNFET 335
>Hs20535816 [T] KOG0695 Serine/threonine protein kinase
Length = 592
Score = 120 bits (301), Expect = 8e-27
Identities = 58/147 (39%), Positives = 99/147 (66%), Gaps = 1/147 (0%)
Query: 346 DFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLA-GSDS 404
DF+ ++VIG+G++ +V LV+ K +IYAMK + K +++ + + V+ E+ V S +
Sbjct: 251 DFDLIRVIGRGSYAKVLLVRLKKNDQIYAMKVVKKELVHDDEDIDWVQTEKHVFEQASSN 310
Query: 405 PWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKL 464
P++V L+ FQ + L+L++E++ GGDLM + R + E+ RFY AE +A+ +H+
Sbjct: 311 PFLVGLHSCFQTTSRLFLVIEYVNGGDLMFHMQRQRKLPEEHARFYAAEICIALNFLHER 370
Query: 465 GFIHRDIKPDNILIDIRGHIKLSDFGL 491
G I+RD+K DN+L+D GHIKL+D+G+
Sbjct: 371 GIIYRDLKLDNVLLDADGHIKLTDYGM 397
Score = 71.2 bits (173), Expect = 5e-12
Identities = 43/130 (33%), Positives = 72/130 (55%), Gaps = 12/130 (9%)
Query: 576 GTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPF--CSETPQ---ETYRKIMNFE 630
GTP+YIAPEI + YG DWW+LG +M+E + G PF ++ P E Y + E
Sbjct: 413 GTPNYIAPEILRGEEYGFSVDWWALGVLMFEMMAGRSPFDIITDNPDMNTEDYLFQVILE 472
Query: 631 QTLQFPDDIHISYEAEDLIRRLLTHS-ENRLG--RHGGADEIKAHPFFSGVDWNTIRQVE 687
+ ++ P +S +A +++ L + RLG G +IK+H FF +DW+ + + +
Sbjct: 473 KPIRIPR--FLSVKASHVLKGFLNKDPKERLGCRPQTGFSDIKSHAFFRSIDWDLLEKKQ 530
Query: 688 A--PYIPKLS 695
A P+ P+++
Sbjct: 531 ALPPFQPQIT 540
>Hs10864650 [T] KOG0695 Serine/threonine protein kinase
Length = 592
Score = 120 bits (301), Expect = 8e-27
Identities = 58/147 (39%), Positives = 99/147 (66%), Gaps = 1/147 (0%)
Query: 346 DFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLA-GSDS 404
DF+ ++VIG+G++ +V LV+ K +IYAMK + K +++ + + V+ E+ V S +
Sbjct: 251 DFDLIRVIGRGSYAKVLLVRLKKNDQIYAMKVVKKELVHDDEDIDWVQTEKHVFEQASSN 310
Query: 405 PWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKL 464
P++V L+ FQ + L+L++E++ GGDLM + R + E+ RFY AE +A+ +H+
Sbjct: 311 PFLVGLHSCFQTTSRLFLVIEYVNGGDLMFHMQRQRKLPEEHARFYAAEICIALNFLHER 370
Query: 465 GFIHRDIKPDNILIDIRGHIKLSDFGL 491
G I+RD+K DN+L+D GHIKL+D+G+
Sbjct: 371 GIIYRDLKLDNVLLDADGHIKLTDYGM 397
Score = 71.2 bits (173), Expect = 5e-12
Identities = 43/130 (33%), Positives = 72/130 (55%), Gaps = 12/130 (9%)
Query: 576 GTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPF--CSETPQ---ETYRKIMNFE 630
GTP+YIAPEI + YG DWW+LG +M+E + G PF ++ P E Y + E
Sbjct: 413 GTPNYIAPEILRGEEYGFSVDWWALGVLMFEMMAGRSPFDIITDNPDMNTEDYLFQVILE 472
Query: 631 QTLQFPDDIHISYEAEDLIRRLLTHS-ENRLG--RHGGADEIKAHPFFSGVDWNTIRQVE 687
+ ++ P +S +A +++ L + RLG G +IK+H FF +DW+ + + +
Sbjct: 473 KPIRIPR--FLSVKASHVLKGFLNKDPKERLGCRPQTGFSDIKSHAFFRSIDWDLLEKKQ 530
Query: 688 A--PYIPKLS 695
A P+ P+++
Sbjct: 531 ALPPFQPQIT 540
>CE02604 [T] KOG0695 Serine/threonine protein kinase
Length = 597
Score = 120 bits (301), Expect = 8e-27
Identities = 62/149 (41%), Positives = 99/149 (65%), Gaps = 3/149 (2%)
Query: 345 DDFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQ-LAHVKAERDVL-AGS 402
+DF + VIG+G++ +V + T +IYA+K ++K EM+N+D+ + V+ E+ V A S
Sbjct: 251 NDFRLLTVIGRGSYAKVVQAEHVSTRQIYAIK-IIKKEMFNEDEDIDWVQTEKSVFEAAS 309
Query: 403 DSPWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIH 462
+ P++V L+ FQ L+ ++EF+PGGDLM + + + E+ RFY E ILA+ +H
Sbjct: 310 NYPFLVGLHSCFQTESRLFFVIEFVPGGDLMFHMQQQRKLPEEHARFYSGEIILALHFLH 369
Query: 463 KLGFIHRDIKPDNILIDIRGHIKLSDFGL 491
G I+RD+K DN+LID GHIKL+D+G+
Sbjct: 370 SRGIIYRDLKLDNVLIDAEGHIKLTDYGM 398
Score = 75.9 bits (185), Expect = 2e-13
Identities = 54/158 (34%), Positives = 76/158 (47%), Gaps = 20/158 (12%)
Query: 576 GTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPF------CSETPQETYRKIMNF 629
GTP+YIAPEI YG DWW+LG +M+E + G PF SE E Y +
Sbjct: 414 GTPNYIAPEILRGDEYGFSVDWWALGVLMFEMMAGRSPFDIVGMQNSEENTEDYLFQIIL 473
Query: 630 EQTLQFPDDIHISYEAEDLIRRLLTHSEN-----RLGRHGGADEIKAHPFFSG-VDWNTI 683
E+ ++ P +S A +++ L +L + G ++K H FF G +DW +
Sbjct: 474 ERQIRIPRS--LSVRASGILKGFLNKDPTERLGCKLDINEGLRDMKEHQFFRGFIDWEAL 531
Query: 684 RQ--VEAPYIPKLSSVTDTRFFP---TDELENV-PDSP 715
Q V PY P + S D F TDEL + PD+P
Sbjct: 532 EQKAVAPPYHPAVESDRDLTHFDHQFTDELPQLSPDNP 569
>7302860 [T] KOG0696 Serine/threonine protein kinase
Length = 679
Score = 120 bits (300), Expect = 1e-26
Identities = 59/147 (40%), Positives = 93/147 (63%), Gaps = 1/147 (0%)
Query: 346 DFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLA-GSDS 404
DFN +KV+GKG+FG+V L ++K + ++YA+K L K + D + E+ VLA G
Sbjct: 349 DFNFIKVLGKGSFGKVLLAERKGSEELYAIKILKKDVIIQDDDVECTMIEKRVLALGEKP 408
Query: 405 PWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKL 464
P++V L+ FQ L+ +ME++ GGDLM + ++ F E V FY AE + +H
Sbjct: 409 PFLVQLHSCFQTMDRLFFVMEYVNGGDLMFQIQQFGKFKEPVAVFYAAEIAAGLFFLHTK 468
Query: 465 GFIHRDIKPDNILIDIRGHIKLSDFGL 491
G ++RD+K DN+L+D GH+K++DFG+
Sbjct: 469 GILYRDLKLDNVLLDADGHVKIADFGM 495
Score = 103 bits (256), Expect = 1e-21
Identities = 54/132 (40%), Positives = 77/132 (57%), Gaps = 8/132 (6%)
Query: 576 GTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQF 635
GTPDYIAPEI LYQ YG+ DWW+ G ++YE L+G PPF E +E + I + + +
Sbjct: 511 GTPDYIAPEIILYQPYGKSVDWWAYGVLLYEMLVGQPPFDGEDEEELFAAIT--DHNVSY 568
Query: 636 PDDIHISYEAEDLIRRLLTHSEN-RLG-RHGGADEIKAHPFFSGVDWNTI--RQVEAPYI 691
P +S EA++ + LT N RLG G ++++ HPFF +DW I R+V+ P+
Sbjct: 569 PKS--LSKEAKEACKGFLTKQPNKRLGCGSSGEEDVRLHPFFRRIDWEKIENREVQPPFK 626
Query: 692 PKLSSVTDTRFF 703
PK+ D F
Sbjct: 627 PKIKHRKDVSNF 638
>Hs4505695 [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 556
Score = 119 bits (299), Expect = 1e-26
Identities = 57/146 (39%), Positives = 94/146 (64%)
Query: 345 DDFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDS 404
+DF K++G+G+F V L ++ T + YA+K L K + ++++ +V ERDV++ D
Sbjct: 80 EDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDH 139
Query: 405 PWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKL 464
P+ V LY++FQD + LY + + G+L+ + + F E TRFY AE + A+E +H
Sbjct: 140 PFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHGK 199
Query: 465 GFIHRDIKPDNILIDIRGHIKLSDFG 490
G IHRD+KP+NIL++ HI+++DFG
Sbjct: 200 GIIHRDLKPENILLNEDMHIQITDFG 225
Score = 75.5 bits (184), Expect = 3e-13
Identities = 50/161 (31%), Positives = 82/161 (50%), Gaps = 12/161 (7%)
Query: 543 NTMLVDAIHLTMTNRQQMQTWR-KSRRLMAYSTVGTPDYIAPEIFLYQGYGQECDWWSLG 601
N +L + +H+ +T+ + +S++ A S VGT Y++PE+ + + D W+LG
Sbjct: 210 NILLNEDMHIQITDFGTAKVLSPESKQARANSFVGTAQYVSPELLTEKSACKSSDLWALG 269
Query: 602 AIMYECLIGWPPFCSETPQETYRKIMNFEQTLQFPDDIHISYEAEDLIRRLLT-HSENRL 660
I+Y+ + G PPF + ++KI+ E FP+ +A DL+ +LL + RL
Sbjct: 270 CIIYQLVAGLPPFRAGNEYLIFQKIIKLE--YDFPEKFF--PKARDLVEKLLVLDATKRL 325
Query: 661 G--RHGGADEIKAHPFFSGVDWNTIRQVEAP----YIPKLS 695
G G +KAHPFF V W + Q P Y+P +S
Sbjct: 326 GCEEMEGYGPLKAHPFFESVTWENLHQQTPPKLTAYLPAMS 366
>Hs5453972 [T] KOG0694 Serine/threonine protein kinase
Length = 682
Score = 119 bits (298), Expect = 2e-26
Identities = 60/148 (40%), Positives = 93/148 (62%), Gaps = 1/148 (0%)
Query: 345 DDFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLA-GSD 403
D+F ++V+GKG+FG+V L + K+TG +YA+K L K + D + E+ +L+ +
Sbjct: 352 DNFEFIRVLGKGSFGKVMLARVKETGDLYAVKVLKKDVILLDDDVECTMTEKRILSLARN 411
Query: 404 SPWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHK 463
P++ L+ FQ L+ +MEF+ GGDLM + + + F E RFY AE I A+ +H
Sbjct: 412 HPFLTQLFCCFQTPDRLFFVMEFVNGGDLMFHIQKSRRFDEARARFYAAEIISALMFLHD 471
Query: 464 LGFIHRDIKPDNILIDIRGHIKLSDFGL 491
G I+RD+K DN+L+D GH KL+DFG+
Sbjct: 472 KGIIYRDLKLDNVLLDHEGHCKLADFGM 499
Score = 92.8 bits (229), Expect = 2e-18
Identities = 52/142 (36%), Positives = 77/142 (53%), Gaps = 9/142 (6%)
Query: 576 GTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQF 635
GTPDYIAPEI YG DWW++G ++YE L G PF +E + + I+N E + +
Sbjct: 515 GTPDYIAPEILQEMLYGPAVDWWAMGVLLYEMLCGHAPFEAENEDDLFEAILNDE--VVY 572
Query: 636 PDDIHISYEAEDLIRRLLTHSEN-RLG--RHGGADEIKAHPFFSGVDWNTI--RQVEAPY 690
P +H +A +++ +T + RLG GG I HPFF +DW + RQ+E P+
Sbjct: 573 PTWLH--EDATGILKSFMTKNPTMRLGSLTQGGEHAILRHPFFKEIDWAQLNHRQIEPPF 630
Query: 691 IPKLSSVTDTRFFPTDELENVP 712
P++ S D F D ++ P
Sbjct: 631 RPRIKSREDVSNFDPDFIKEEP 652
>Hs22043324 [T] KOG0603 Ribosomal protein S6 kinase
Length = 192
Score = 119 bits (298), Expect = 2e-26
Identities = 61/131 (46%), Positives = 92/131 (69%), Gaps = 4/131 (3%)
Query: 347 FNSVKVIGKGAFGEVRLVQK---KDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSD 403
F +KV+G+G+FG+V LV+K D+G +YAMK L K+ + +D++ K ERD+LA +
Sbjct: 62 FELLKVLGQGSFGKVFLVRKVTRPDSGHLYAMKVLKKATLKVRDRV-RTKMERDILADVN 120
Query: 404 SPWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHK 463
P+VV L+Y+FQ LYLI++FL GGDL T L + +FTE+ +FY+AE L ++ +H
Sbjct: 121 HPFVVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALGLDHLHS 180
Query: 464 LGFIHRDIKPD 474
LG I+RD+KP+
Sbjct: 181 LGIIYRDLKPE 191
>YBR028c [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 525
Score = 119 bits (297), Expect = 2e-26
Identities = 65/173 (37%), Positives = 98/173 (56%), Gaps = 26/173 (15%)
Query: 346 DFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMY-------------------NK 386
DF V+V+G+GA+G+V LV+ +T K+YAMK L K+E+ N
Sbjct: 127 DFKPVRVLGQGAYGKVLLVKDVNTSKLYAMKQLRKAEILISQTATDSKREDEDKNDGNNN 186
Query: 387 D-------QLAHVKAERDVLAGSDSPWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRW 439
D +L AER +L+ + P +V L+YSF D+ LYL+++++PGG+L L
Sbjct: 187 DNDDGLSKRLERTFAERSILSEIEHPNIVKLFYSFHDNSKLYLLLQYIPGGELFYHLKEH 246
Query: 440 QIFTEDVTRFYMAECILAIEVIHKLGFIHRDIKPDNILIDIRGHIKLSDFGLS 492
E FY AE A+ +H G ++RD+KP+N L++ RGH+ L+DFGLS
Sbjct: 247 GTLDETTVSFYAAEISCALRFLHTKGVVYRDLKPENCLLNQRGHLVLTDFGLS 299
Score = 70.5 bits (171), Expect = 9e-12
Identities = 32/82 (39%), Positives = 49/82 (59%), Gaps = 2/82 (2%)
Query: 572 YSTVGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQ 631
YS +GTP+Y APEI L + Y Q CDW+SLG ++Y+ L+G PP+ + KI +Q
Sbjct: 320 YSIIGTPEYCAPEILLGKAYSQNCDWYSLGCLLYDMLVGKPPYTGSNHKVIINKIQQNKQ 379
Query: 632 TLQFPDDIHISYEAEDLIRRLL 653
+ P ++S +D++ LL
Sbjct: 380 GPKIP--FYLSEGMKDILNALL 399
>Hs4506071 [T] KOG0695 Serine/threonine protein kinase
Length = 587
Score = 119 bits (297), Expect = 2e-26
Identities = 59/147 (40%), Positives = 97/147 (65%), Gaps = 1/147 (0%)
Query: 346 DFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLA-GSDS 404
DF+ ++VIG+G++ +V LV+ K T +IYAMK + K + + + + V+ E+ V S+
Sbjct: 244 DFDLLRVIGRGSYAKVLLVRLKKTDRIYAMKVVKKELVNDDEDIDWVQTEKHVFEQASNH 303
Query: 405 PWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKL 464
P++V L+ FQ L+ ++E++ GGDLM + R + E+ RFY AE LA+ +H+
Sbjct: 304 PFLVGLHSCFQTESRLFFVIEYVNGGDLMFHMQRQRKLPEEHARFYSAEISLALNYLHER 363
Query: 465 GFIHRDIKPDNILIDIRGHIKLSDFGL 491
G I+RD+K DN+L+D GHIKL+D+G+
Sbjct: 364 GIIYRDLKLDNVLLDSEGHIKLTDYGM 390
Score = 77.8 bits (190), Expect = 6e-14
Identities = 48/132 (36%), Positives = 72/132 (54%), Gaps = 14/132 (10%)
Query: 576 GTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPF----CSETPQ---ETYRKIMN 628
GTP+YIAPEI + YG DWW+LG +M+E + G PF S+ P E Y +
Sbjct: 406 GTPNYIAPEILRGEDYGFSVDWWALGVLMFEMMAGRSPFDIVGSSDNPDQNTEDYLFQVI 465
Query: 629 FEQTLQFPDDIHISYEAEDLIRRLLTHS-ENRLGRH--GGADEIKAHPFFSGVDWNTI-- 683
E+ ++ P +S +A +++ L + RLG H G +I+ HPFF VDW+ +
Sbjct: 466 LEKQIRIPRS--LSVKAASVLKSFLNKDPKERLGCHPQTGFADIQGHPFFRNVDWDMMEQ 523
Query: 684 RQVEAPYIPKLS 695
+QV P+ P +S
Sbjct: 524 KQVVPPFKPNIS 535
>7303111 [T] KOG0695 Serine/threonine protein kinase
Length = 690
Score = 119 bits (297), Expect = 2e-26
Identities = 58/148 (39%), Positives = 98/148 (66%), Gaps = 1/148 (0%)
Query: 345 DDFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVL-AGSD 403
+DF ++VIG+G++ +V +V+ + T +IYAMK + K+ + + + + V+ E+ V S+
Sbjct: 259 NDFELIRVIGRGSYAKVLMVELRRTRRIYAMKVIKKALVTDDEDIDWVQTEKHVFETASN 318
Query: 404 SPWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHK 463
P++V L+ FQ L+ ++EF+ GGDLM + R + E+ RFY AE LA+ +H+
Sbjct: 319 HPFLVGLHSCFQTPSRLFFVIEFVRGGDLMYHMQRQRRLPEEHARFYAAEISLALNFLHE 378
Query: 464 LGFIHRDIKPDNILIDIRGHIKLSDFGL 491
G I+RD+K DN+L+D GHIKL+D+G+
Sbjct: 379 KGIIYRDLKLDNVLLDHEGHIKLTDYGM 406
Score = 84.7 bits (208), Expect = 5e-16
Identities = 53/143 (37%), Positives = 76/143 (53%), Gaps = 14/143 (9%)
Query: 576 GTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPF----CSETPQ---ETYRKIMN 628
GTP+YIAPEI + YG DWW+LG ++YE L G PF SE P E Y +
Sbjct: 422 GTPNYIAPEILRGEDYGFSVDWWALGVLLYEMLAGRSPFDLAGASENPDQNTEDYLFQVI 481
Query: 629 FEQTLQFPDDIHISYEAEDLIRRLLT-HSENRLG--RHGGADEIKAHPFFSGVDWNTI-- 683
E+T++ P +S A +++ L + +RLG R +I +HPFF +DW +
Sbjct: 482 LEKTIRIPRS--LSVRAASVLKGFLNKNPADRLGCHRESAFMDIVSHPFFKNMDWELLER 539
Query: 684 RQVEAPYIPKLSSVTDTRFFPTD 706
+QV P+ P+L S D FP +
Sbjct: 540 KQVTPPFKPRLDSDRDLANFPPE 562
>YOL100w [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 1081
Score = 118 bits (296), Expect = 3e-26
Identities = 69/206 (33%), Positives = 115/206 (55%), Gaps = 13/206 (6%)
Query: 297 IERNQRRLELESELASQDWSEERKNRQLASLGKKESQFXXXXXXXXXXDDFNSVKVIGKG 356
+E+N+ ++++E + +SQ + ++ ++ KK + DF VIG G
Sbjct: 141 MEKNRNKVKIEHDSSSQKPIAKESSKAQKNIIKKGIK------------DFKFGSVIGDG 188
Query: 357 AFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAG-SDSPWVVSLYYSFQ 415
A+ V L DT K YA K L K + + ++ +V E+ L ++SP VV L+ +FQ
Sbjct: 189 AYSTVMLATSIDTKKRYAAKVLNKEYLIRQKKVKYVSIEKTALQKLNNSPSVVRLFSTFQ 248
Query: 416 DSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKLGFIHRDIKPDN 475
D LY ++E+ P GD ++++ ++ E R+Y A+ I AI+ +H G IHRDIKP+N
Sbjct: 249 DESSLYFLLEYAPNGDFLSLMKKYGSLDETCARYYAAQIIDAIDYLHSNGIIHRDIKPEN 308
Query: 476 ILIDIRGHIKLSDFGLSTGFHKTHDS 501
IL+D IKL+DFG + + T++S
Sbjct: 309 ILLDGEMKIKLTDFGTAKLLNPTNNS 334
Score = 53.9 bits (128), Expect = 9e-07
Identities = 33/110 (30%), Positives = 55/110 (50%), Gaps = 11/110 (10%)
Query: 573 STVGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQ- 631
S VGT +Y++PE+ CD W+ G I+++ + G PPF + T++K+M +
Sbjct: 348 SFVGTAEYVSPELLNDSFTDYRCDIWAFGCILFQMIAGKPPFKATNEYLTFQKVMKVQYA 407
Query: 632 -TLQFPDDIHISYEAEDLIRRLLTHSENRLGRHGGADEIKAHPFFSGVDW 680
T FP I DL++++L L R +IK H FF +++
Sbjct: 408 FTPGFPLII------RDLVKKILV---KNLDRRLTISQIKEHHFFKDLNF 448
>CE05274 [T] KOG0690 Serine/threonine protein kinase
Length = 546
Score = 117 bits (294), Expect = 5e-26
Identities = 63/152 (41%), Positives = 95/152 (62%), Gaps = 5/152 (3%)
Query: 345 DDFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDS 404
+DF+ +KV+GKG FG+V L ++K T K+YA+K L K + ++++AH E VL
Sbjct: 191 EDFDFLKVLGKGTFGKVILCKEKRTQKLYAIKILKKDVIIAREEVAHTLTENRVLQRCKH 250
Query: 405 PWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIR-----WQIFTEDVTRFYMAECILAIE 459
P++ L YSFQ + L +MEF GGDL L R + F+E RFY +E +LA+
Sbjct: 251 PFLTELKYSFQTNDRLCFVMEFAIGGDLYYHLNREVQMNKEGFSEPRARFYGSEIVLALG 310
Query: 460 VIHKLGFIHRDIKPDNILIDIRGHIKLSDFGL 491
+H ++RD+K +N+L+D GHIK++DFGL
Sbjct: 311 YLHANSIVYRDLKLENLLLDKDGHIKIADFGL 342
Score = 82.0 bits (201), Expect = 3e-15
Identities = 52/137 (37%), Positives = 73/137 (52%), Gaps = 12/137 (8%)
Query: 576 GTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQF 635
GTP+Y+APE+ YG+ DWW +G +MYE + G PF S+ + + IM + L+F
Sbjct: 358 GTPEYLAPEVLDDHDYGRCVDWWGVGVVMYEMMCGRLPFYSKDHNKLFELIMAGD--LRF 415
Query: 636 PDDIHISYEAEDLIRRLLTHS-ENRLGRHGGAD---EIKAHPFFSGVDWNTI--RQVEAP 689
P +S EA L+ LL RLG GG + EI FF VDW +++E P
Sbjct: 416 PS--KLSQEARTLLTGLLVKDPTQRLG--GGPEDALEICRADFFRTVDWEATYRKEIEPP 471
Query: 690 YIPKLSSVTDTRFFPTD 706
Y P + S TDT +F +
Sbjct: 472 YKPNVQSETDTSYFDNE 488
>CE02074 [T] KOG0986 G protein-coupled receptor kinase
Length = 727
Score = 116 bits (291), Expect = 1e-25
Identities = 63/157 (40%), Positives = 94/157 (59%), Gaps = 4/157 (2%)
Query: 345 DDFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLA---- 400
+DF+ ++IG+G FGEV +K DTGK+YAMK L K + K ER +L+
Sbjct: 189 NDFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALNERIMLSLVST 248
Query: 401 GSDSPWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEV 460
G D P++V + Y+FQ L I++ + GGDL L + +FTE FY +E IL +E
Sbjct: 249 GQDCPFIVCMTYAFQSPDKLCFILDLMNGGDLHYHLSQHGVFTEQEMIFYASEVILGLEH 308
Query: 461 IHKLGFIHRDIKPDNILIDIRGHIKLSDFGLSTGFHK 497
+H ++RD+KP NIL+D GH+++SD GL+ + K
Sbjct: 309 MHNRFVVYRDLKPANILLDENGHVRVSDLGLACDYSK 345
Score = 74.7 bits (182), Expect = 5e-13
Identities = 53/152 (34%), Positives = 79/152 (51%), Gaps = 14/152 (9%)
Query: 572 YSTVGTPDYIAPEIFLYQG--YGQECDWWSLGAIMYECLIGWPPFCSETPQETYR-KIMN 628
+++VGT Y+APE+ L +G Y DW+SLG ++Y+ L G PF ++ M
Sbjct: 349 HASVGTHGYMAPEV-LAKGVAYDSSADWFSLGCMLYKLLKGHSPFRQHKSKDKNEIDKMT 407
Query: 629 FEQTLQFPDDIHISYEAEDLIRRLLTHS-ENRLGRHG-GADEIKAHPFFSGVDWNTI--R 684
Q ++ P++ +S + DL+ LL +RLG G G E+K HPFF VDW T+ R
Sbjct: 408 LTQDIELPNE-GLSKDCRDLLEGLLKRDVPDRLGCRGKGPTEVKEHPFFKDVDWQTVYLR 466
Query: 685 QVEAPYIPKLSSVT-----DTRFFPTDELENV 711
++ P IP V D F DE++ V
Sbjct: 467 RMTPPLIPPRGEVNAADAFDIGNFDDDEVKGV 498
>At5g47750 [R] KOG0610 Putative serine/threonine protein kinase
Length = 586
Score = 116 bits (291), Expect = 1e-25
Identities = 59/148 (39%), Positives = 93/148 (61%), Gaps = 2/148 (1%)
Query: 347 FNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDSPW 406
F +K +G G G V L + T +AMK + K+ + ++ +L + ER++L D P+
Sbjct: 191 FRLLKRLGCGDIGSVYLSELSGTKCYFAMKVMDKTSLASRKKLLRAQTEREILQSLDHPF 250
Query: 407 VVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRW--QIFTEDVTRFYMAECILAIEVIHKL 464
+ +LY F+ ++ L+MEF PGGDL T+ R + F+E +FY+AE +LA+E +H L
Sbjct: 251 LPTLYTHFETEKFSCLVMEFCPGGDLHTLRQRQPGKHFSEQAVKFYIAESLLALEYLHML 310
Query: 465 GFIHRDIKPDNILIDIRGHIKLSDFGLS 492
G ++RD+KP+N+L+ GHI LSDF LS
Sbjct: 311 GIVYRDLKPENVLVREDGHIMLSDFDLS 338
Score = 102 bits (253), Expect = 3e-21
Identities = 54/122 (44%), Positives = 71/122 (57%), Gaps = 3/122 (2%)
Query: 573 STVGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQT 632
S VGT +Y+APEI +G+G DWW+ G +YE L G PF ++T ++ Q
Sbjct: 426 SFVGTHEYLAPEIIKGEGHGSAVDWWTFGIFLYELLFGRTPFKGSGNRQTLFNVVG--QP 483
Query: 633 LQFPDDIHISYEAEDLIRRLL-THSENRLGRHGGADEIKAHPFFSGVDWNTIRQVEAPYI 691
L+FP+ +S+ A DLIR LL + RLG GA E+K HPFF GV+W IR P I
Sbjct: 484 LRFPETPVVSFAARDLIRGLLMKEPQQRLGFKRGATEVKQHPFFEGVNWALIRCATPPEI 543
Query: 692 PK 693
PK
Sbjct: 544 PK 545
>At3g27580 [R] KOG0610 Putative serine/threonine protein kinase
Length = 578
Score = 116 bits (291), Expect = 1e-25
Identities = 60/149 (40%), Positives = 91/149 (60%), Gaps = 2/149 (1%)
Query: 346 DFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDSP 405
DF +K +G G G V L + TG +A+K + K+ + + +L + E+++L D P
Sbjct: 181 DFKLIKKLGGGDIGNVYLAELIGTGVSFAVKVMEKAAIAARKKLVRAQTEKEILQSLDHP 240
Query: 406 WVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLI--RWQIFTEDVTRFYMAECILAIEVIHK 463
++ +LY F+ L+MEF PGGDL ++ R + F E RFY+AE +LA+E +H
Sbjct: 241 FLPTLYSHFETEMNSCLVMEFCPGGDLHSLRQKQRGKYFPEQAARFYVAEVLLAMEYLHM 300
Query: 464 LGFIHRDIKPDNILIDIRGHIKLSDFGLS 492
LG I+RD+KP+N+L+ GHI LSDF LS
Sbjct: 301 LGIIYRDLKPENVLVREDGHIMLSDFDLS 329
Score = 98.6 bits (244), Expect = 3e-20
Identities = 52/122 (42%), Positives = 70/122 (56%), Gaps = 3/122 (2%)
Query: 573 STVGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQT 632
S VGT +Y+APEI +G+G DWW+ G +YE L G PF + T ++ Q
Sbjct: 415 SFVGTHEYLAPEIIKGEGHGSAVDWWTFGIFLYELLFGITPFRGGDNRATLFNVVG--QP 472
Query: 633 LQFPDDIHISYEAEDLIRRLLT-HSENRLGRHGGADEIKAHPFFSGVDWNTIRQVEAPYI 691
L+FP+ ++S+ A DLIR LL ++RL GA EIK HPFF V+W IR P I
Sbjct: 473 LRFPEHPNVSFAARDLIRGLLVKEPQHRLAYRRGATEIKQHPFFQSVNWALIRCTSPPQI 532
Query: 692 PK 693
P+
Sbjct: 533 PQ 534
>Hs10835065 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 277
Score = 116 bits (290), Expect = 1e-25
Identities = 54/147 (36%), Positives = 92/147 (61%)
Query: 346 DFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDSP 405
D +++ +G G FG V LV++K +A+K + ++ + Q HV E+ VL P
Sbjct: 48 DCDALVTMGTGTFGRVHLVKEKTAKHFFALKVMSIPDVIRRKQEQHVHNEKSVLKEVSHP 107
Query: 406 WVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKLG 465
+++ L++++ + ++LY++ME++PGG+L + L F+ FY AE I AIE +H
Sbjct: 108 FLIRLFWTWHEERFLYMLMEYVPGGELFSYLRNRGHFSSTTGLFYSAEIICAIEYLHSKE 167
Query: 466 FIHRDIKPDNILIDIRGHIKLSDFGLS 492
++RD+KP+NIL+D GHIKL+DFG +
Sbjct: 168 IVYRDLKPENILLDRDGHIKLTDFGFA 194
Score = 65.1 bits (157), Expect = 4e-10
Identities = 29/72 (40%), Positives = 46/72 (63%), Gaps = 4/72 (5%)
Query: 572 YSTVGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQ 631
++ GTP+Y+APE+ +G+G+ DWW+LG +++E L G+PPF + P Y+KI+
Sbjct: 202 WTLCGTPEYLAPEVIQSKGHGRAVDWWALGILIFEMLSGFPPFFDDNPFGIYQKIL--AG 259
Query: 632 TLQFPD--DIHI 641
L FP D H+
Sbjct: 260 KLYFPRHLDFHV 271
>Hs4506067 [T] KOG0696 Serine/threonine protein kinase
Length = 672
Score = 115 bits (289), Expect = 2e-25
Identities = 60/147 (40%), Positives = 90/147 (60%), Gaps = 1/147 (0%)
Query: 346 DFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDSP 405
DFN + V+GKG+FG+V L +K T ++YA+K L K + D + E+ VLA D P
Sbjct: 338 DFNFLMVLGKGSFGKVMLADRKGTEELYAIKILKKDVVIQDDDVECTMVEKRVLALLDKP 397
Query: 406 -WVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKL 464
++ L+ FQ LY +ME++ GGDLM + + F E FY AE + + +HK
Sbjct: 398 PFLTQLHSCFQTVDRLYFVMEYVNGGDLMYHIQQVGKFKEPQAVFYAAEISIGLFFLHKR 457
Query: 465 GFIHRDIKPDNILIDIRGHIKLSDFGL 491
G I+RD+K DN+++D GHIK++DFG+
Sbjct: 458 GIIYRDLKLDNVMLDSEGHIKIADFGM 484
Score = 95.9 bits (237), Expect = 2e-19
Identities = 50/123 (40%), Positives = 72/123 (57%), Gaps = 8/123 (6%)
Query: 576 GTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQF 635
GTPDYIAPEI YQ YG+ DWW+ G ++YE L G PPF E E ++ IM E + +
Sbjct: 500 GTPDYIAPEIIAYQPYGKSVDWWAYGVLLYEMLAGQPPFDGEDEDELFQSIM--EHNVSY 557
Query: 636 PDDIHISYEAEDLIRRLLT-HSENRLG-RHGGADEIKAHPFFSGVDWNTI--RQVEAPYI 691
P +S EA + + L+T H RLG G +++ H FF +DW + R+++ P+
Sbjct: 558 PKS--LSKEAVSICKGLMTKHPAKRLGCGPEGERDVREHAFFRRIDWEKLENREIQPPFK 615
Query: 692 PKL 694
PK+
Sbjct: 616 PKV 618
>Hs4501971 [T] KOG0986 G protein-coupled receptor kinase
Length = 689
Score = 115 bits (289), Expect = 2e-25
Identities = 63/156 (40%), Positives = 94/156 (59%), Gaps = 3/156 (1%)
Query: 345 DDFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLA---G 401
+DF+ ++IG+G FGEV +K+DTGK+YAMK L K + K ER +L+
Sbjct: 189 NDFSVHRIIGRGGFGEVYGCRKRDTGKMYAMKCLDKKRIKMKQGETLALNERIMLSLVST 248
Query: 402 SDSPWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVI 461
D P++V + Y+F L I++ + GGDL L + +F+E RFY AE IL +E +
Sbjct: 249 GDCPFIVCMSYAFHTPDKLSFILDLMNGGDLHYHLSQHGVFSEADMRFYAAEIILGLEHM 308
Query: 462 HKLGFIHRDIKPDNILIDIRGHIKLSDFGLSTGFHK 497
H ++RD+KP NIL+D GH+++SD GL+ F K
Sbjct: 309 HNRFVVYRDLKPANILLDEHGHVRISDLGLACDFSK 344
Score = 63.9 bits (154), Expect = 9e-10
Identities = 45/135 (33%), Positives = 67/135 (49%), Gaps = 14/135 (10%)
Query: 572 YSTVGTPDYIAPEIFLYQG--YGQECDWWSLGAIMYECLIGWPPFCSETPQETYR-KIMN 628
+++VGT Y+APE+ L +G Y DW+SLG ++++ L G PF ++ + M
Sbjct: 348 HASVGTHGYMAPEV-LQKGVAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHEIDRMT 406
Query: 629 FEQTLQFPDDIHISYEAEDLIRRLLTHSENR----LGRHGGADEIKAHPFFSGVDWNTI- 683
++ PD S E L+ LL NR LGR GA E+K PFF +DW +
Sbjct: 407 LTMAVELPDS--FSPELHSLLEGLLQRDVNRRLGCLGR--GAQEVKESPFFRSLDWQMVF 462
Query: 684 -RQVEAPYIPKLSSV 697
++ P IP V
Sbjct: 463 LQRYPPPLIPPRGEV 477
>At4g26610 [R] KOG0610 Putative serine/threonine protein kinase
Length = 506
Score = 115 bits (288), Expect = 3e-25
Identities = 59/148 (39%), Positives = 92/148 (61%), Gaps = 2/148 (1%)
Query: 347 FNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDSPW 406
F +K +G G G V L + T +AMK + K + ++ +L + ER++L D P+
Sbjct: 123 FRLLKRLGCGDIGTVHLAELHGTRCFFAMKVMDKGALASRKKLLRAQTEREILQCLDHPF 182
Query: 407 VVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRW--QIFTEDVTRFYMAECILAIEVIHKL 464
+ +LY F+ ++ L+MEF PGGDL T+ R + F+E +FY+AE +LA+E +H L
Sbjct: 183 LPTLYSHFETEKFSCLVMEFCPGGDLHTLRQRQPGKRFSEQAAKFYVAEVLLAMEYLHML 242
Query: 465 GFIHRDIKPDNILIDIRGHIKLSDFGLS 492
G I+RD+KP+N+L+ GH+ LSDF LS
Sbjct: 243 GIIYRDLKPENVLVRDDGHVMLSDFDLS 270
Score = 99.8 bits (247), Expect = 1e-20
Identities = 52/122 (42%), Positives = 70/122 (56%), Gaps = 3/122 (2%)
Query: 573 STVGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQT 632
S VGT +Y+APEI +G+G DWW+ G +YE L G PF + T ++ Q
Sbjct: 355 SFVGTHEYLAPEIIKGEGHGSAVDWWTFGIFLYELLFGKTPFKGSGNRATLFNVVG--QP 412
Query: 633 LQFPDDIHISYEAEDLIRRLLT-HSENRLGRHGGADEIKAHPFFSGVDWNTIRQVEAPYI 691
L+FP+ +S+ A DLIR LL ++RL GA E+K HPFF GV+W +R P I
Sbjct: 413 LRFPESPVVSFAARDLIRSLLVKEPQHRLAYKRGATEMKQHPFFEGVNWALVRCASPPEI 472
Query: 692 PK 693
PK
Sbjct: 473 PK 474
>Hs21450709 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 166
Score = 114 bits (286), Expect = 4e-25
Identities = 52/135 (38%), Positives = 91/135 (66%)
Query: 345 DDFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDS 404
D F ++ IGKG+FG+V +VQK DT K+YAMK + K + ++++ +V E ++ G +
Sbjct: 21 DHFEILRAIGKGSFGKVCIVQKNDTKKMYAMKYMNKQKCVERNEVRNVFKELQIMQGLEH 80
Query: 405 PWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKL 464
P++V+L+YSFQD + ++++++ L GGDL L + F E+ + ++ E ++A++ +
Sbjct: 81 PFLVNLWYSFQDEEDMFMVVDLLLGGDLRYHLQQNVHFKEETVKLFICELVMALDYLQNQ 140
Query: 465 GFIHRDIKPDNILID 479
IHRD+KPDNIL+D
Sbjct: 141 RIIHRDMKPDNILLD 155
>CE02586 [T] KOG0696 Serine/threonine protein kinase
Length = 861
Score = 114 bits (285), Expect = 6e-25
Identities = 59/147 (40%), Positives = 93/147 (63%), Gaps = 1/147 (0%)
Query: 346 DFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDSP 405
DFN + V+GKG+FG+V L ++K T +++A+K L K + D + E+ VLA + P
Sbjct: 412 DFNFLTVLGKGSFGKVLLGEQKTTKELFAIKVLKKDVIIQDDDVECTMTEKRVLALPEKP 471
Query: 406 -WVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKL 464
++V+L+ FQ LY +MEF+ GGDLM + + F E V FY AE + + +H
Sbjct: 472 SFLVALHSCFQTMDRLYFVMEFVNGGDLMYQIQQVGKFKEPVAVFYAAEIAVGLFFLHSK 531
Query: 465 GFIHRDIKPDNILIDIRGHIKLSDFGL 491
G I+RD+K DN++++ GHIK++DFG+
Sbjct: 532 GIIYRDLKLDNVMLERDGHIKITDFGM 558
Score = 98.6 bits (244), Expect = 3e-20
Identities = 57/135 (42%), Positives = 75/135 (55%), Gaps = 11/135 (8%)
Query: 576 GTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQF 635
GTPDYIAPEI LYQ YG+ DWW+ G +++E L G PPF E E + I E + +
Sbjct: 574 GTPDYIAPEIILYQPYGKSVDWWAYGVLLFEMLAGQPPFDGEDEDELFTAIT--EHNVSY 631
Query: 636 PDDIHISYEAEDLIRRLL-THSENRLGRHG----GADEIKAHPFFSGVDWNTI--RQVEA 688
P +S EA L + LL + RLG G + +IK HPFF +DW I RQ++
Sbjct: 632 PKS--LSKEAVSLCKALLIKNPSKRLGCTGDDESASRDIKEHPFFRRIDWFKIETRQIQP 689
Query: 689 PYIPKLSSVTDTRFF 703
P+ PKL + T F
Sbjct: 690 PFKPKLKTDRSTENF 704
>7301972 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 393
Score = 114 bits (285), Expect = 6e-25
Identities = 58/141 (41%), Positives = 90/141 (63%)
Query: 352 VIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDSPWVVSLY 411
V+G G+FG V LV++K YA K + K ++ Q+AHV E+ VL + P+++ L
Sbjct: 50 VLGNGSFGTVMLVREKSGKNYYAAKMMSKEDLVRLKQVAHVHNEKHVLNAARFPFLIYLV 109
Query: 412 YSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKLGFIHRDI 471
S + YLYLI+ + GG+L + R + F E RFY A+ LA+E +HK+ ++RD+
Sbjct: 110 DSTKCFDYLYLILPLVNGGELFSYHRRVRKFNEKHARFYAAQVALALEYMHKMHLMYRDL 169
Query: 472 KPDNILIDIRGHIKLSDFGLS 492
KP+NIL+D RG+IK++DFG +
Sbjct: 170 KPENILLDQRGYIKITDFGFT 190
Score = 48.1 bits (113), Expect = 5e-05
Identities = 18/39 (46%), Positives = 26/39 (66%)
Query: 576 GTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPF 614
GTP+Y+APEI + Y + DWW+ G ++YE + G PF
Sbjct: 202 GTPEYLAPEIVQLRPYNKSVDWWAFGILVYEFVAGRSPF 240
>SPAC17G8.14c [T] KOG0694 Serine/threonine protein kinase
Length = 896
Score = 113 bits (282), Expect = 1e-24
Identities = 61/150 (40%), Positives = 94/150 (62%), Gaps = 4/150 (2%)
Query: 345 DDFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDS 404
DDF + V+GKG FG+V L + K K YA+K L K + ++L +K E+ V ++
Sbjct: 570 DDFTFLAVLGKGNFGKVMLAEYKVNKKFYAIKVLKKEAILKNEELESLKTEKHVFEVANK 629
Query: 405 ---PWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVI 461
P++++L+ SFQ S +Y +ME++ GGDLM + R Q F+ RFY AE LA++
Sbjct: 630 EKHPFLLNLFASFQTSTRVYFVMEYILGGDLMVHIQRQQ-FSVKRARFYGAEVCLALKYF 688
Query: 462 HKLGFIHRDIKPDNILIDIRGHIKLSDFGL 491
H+ G +RD+K DNIL+ GHI+++D+GL
Sbjct: 689 HENGIAYRDLKLDNILLCPDGHIRIADYGL 718
Score = 86.3 bits (212), Expect = 2e-16
Identities = 50/132 (37%), Positives = 76/132 (56%), Gaps = 8/132 (6%)
Query: 576 GTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQF 635
GTP+++APEI L Q Y ++ DWW+ G +MY+ L+G PF E +E + I++ E F
Sbjct: 734 GTPEFMAPEILLEQQYSKDVDWWAFGVLMYQMLLGQSPFKGEDEEEIFDAILSDEPL--F 791
Query: 636 PDDIHISYEAEDLIRRLLTHSEN-RLGR-HGGADEIKAHPFFSGVDWNTI--RQVEAPYI 691
P I++ +A L+R LLT N RLG A+E+ AHPFF+ + W+ + + E Y
Sbjct: 792 P--INMPADAVSLLRGLLTRDPNQRLGSGPKDANEVMAHPFFASIVWDDLYNKLYEPSYK 849
Query: 692 PKLSSVTDTRFF 703
P ++ D F
Sbjct: 850 PLINDPRDLNNF 861
>At2g26700_2 [R] KOG0610 Putative serine/threonine protein kinase
Length = 437
Score = 113 bits (282), Expect = 1e-24
Identities = 60/152 (39%), Positives = 93/152 (60%), Gaps = 4/152 (2%)
Query: 345 DDFNSVKVIGKGAFGEVRLVQKKDTGK--IYAMKTLLKSEMYNKDQLAHVKAERDVLAGS 402
+ F +K +G G G V L Q + + + YAMK + K + K +L + E+ +L
Sbjct: 27 EHFRLLKRLGSGDIGSVYLCQIRGSPETAFYAMKVVDKEAVAVKKKLGRAEMEKKILGML 86
Query: 403 DSPWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRW--QIFTEDVTRFYMAECILAIEV 460
D P+ +LY +F+ S Y +L+ME+ PGGDL + +R + FT TRFY AE ++A+E
Sbjct: 87 DHPFCPTLYAAFEASHYSFLVMEYCPGGDLYAVRLRQPSKRFTISSTRFYAAETLVALEY 146
Query: 461 IHKLGFIHRDIKPDNILIDIRGHIKLSDFGLS 492
+H +G ++RD+KP+N+LI GH+ LSDF LS
Sbjct: 147 LHMMGIVYRDLKPENVLIREDGHVMLSDFDLS 178
Score = 92.4 bits (228), Expect = 2e-18
Identities = 48/127 (37%), Positives = 71/127 (55%), Gaps = 6/127 (4%)
Query: 573 STVGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQT 632
S VGT +Y+APE+ QG+G DWW+ G +YE + G PF + ++T I+ T
Sbjct: 269 SFVGTHEYLAPEVISGQGHGSAVDWWTYGIFLYEMIFGRTPFKGDNNEKTLVNILKAPLT 328
Query: 633 -----LQFPDDIHISYEAEDLIRRLLT-HSENRLGRHGGADEIKAHPFFSGVDWNTIRQV 686
+ P + A+DLI +LL + + RLG G+ EIK H FF GV+W IR +
Sbjct: 329 FPKVIVNSPKEYEDMVNAQDLIIKLLVKNPKKRLGSLKGSIEIKRHEFFEGVNWALIRSI 388
Query: 687 EAPYIPK 693
+ P++PK
Sbjct: 389 KPPWVPK 395
>Hs5453978 [T] KOG0614 cGMP-dependent protein kinase
Length = 762
Score = 112 bits (280), Expect = 2e-24
Identities = 59/200 (29%), Positives = 112/200 (55%), Gaps = 5/200 (2%)
Query: 294 GYAIERNQRRLELESELASQDWSEERK-NRQLASLGKKESQFXXXXXXXXXXDDFNSVKV 352
GY N+ + ++ + +W + + ++ L +K ++F + +
Sbjct: 403 GYVANLNRDDEKRHAKRSMSNWKLSKALSLEMIQLKEKVARFSSSSPF----QNLEIIAT 458
Query: 353 IGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDSPWVVSLYY 412
+G G FG V LV+ K+ +AMK + K + + Q HV +E+ +L SP++V LY
Sbjct: 459 LGVGGFGRVELVKVKNENVAFAMKCIRKKHIVDTKQQEHVYSEKRILEELCSPFIVKLYR 518
Query: 413 SFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKLGFIHRDIK 472
+F+D++Y+Y+++E GG+L ++L F E ++F +A A + +H+LG I+RD+K
Sbjct: 519 TFKDNKYVYMLLEACLGGELWSILRDRGSFDEPTSKFCVACVTEAFDYLHRLGIIYRDLK 578
Query: 473 PDNILIDIRGHIKLSDFGLS 492
P+N+++D G++KL DFG +
Sbjct: 579 PENLILDAEGYLKLVDFGFA 598
Score = 82.0 bits (201), Expect = 3e-15
Identities = 52/146 (35%), Positives = 75/146 (50%), Gaps = 15/146 (10%)
Query: 576 GTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQF 635
GTP+Y+APE+ L +G+ D+WSLG ++YE L G PPF TY I+ + + F
Sbjct: 612 GTPEYVAPEVILNKGHDFSVDFWSLGILVYELLTGNPPFSGVDQMMTYNLILKGIEKMDF 671
Query: 636 PDDIHISYEAEDLIRRLLTHS-ENRLGR-HGGADEIKAHPFFSGVDWNTI--RQVEAPYI 691
P I+ EDLIRRL + RLG G ++IK H + +G +W + R + +P
Sbjct: 672 PR--KITRRPEDLIRRLCRQNPTERLGNLKNGINDIKKHRWLNGFNWEGLKARSLPSPLQ 729
Query: 692 PKLSSVTDTRFF---------PTDEL 708
+L D +F P DEL
Sbjct: 730 RELKGPIDHSYFDKYPPEKGMPPDEL 755
>CE03979 [T] KOG0614 cGMP-dependent protein kinase
Length = 581
Score = 112 bits (279), Expect = 3e-24
Identities = 54/148 (36%), Positives = 93/148 (62%), Gaps = 1/148 (0%)
Query: 345 DDFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDS 404
+D V +G G FG V LV+ + + YA+K + K+ + Q +HV +ER +L D+
Sbjct: 272 EDLQRVSTLGMGGFGRVELVRSASS-RTYALKIMNKAHIVETKQESHVVSERRILMQCDN 330
Query: 405 PWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKL 464
++V +Y +++DS+ +Y++ME GG++ T+L + F D+TRFY A + A+E +H+
Sbjct: 331 DYIVRMYKTYRDSEKIYMLMEPCLGGEIWTILRKKGRFDNDLTRFYCAGAMEALEYLHRK 390
Query: 465 GFIHRDIKPDNILIDIRGHIKLSDFGLS 492
++RD+KP+N+L+D G KL DFG +
Sbjct: 391 NIVYRDLKPENMLLDRNGWPKLVDFGFA 418
Score = 72.8 bits (177), Expect = 2e-12
Identities = 44/132 (33%), Positives = 66/132 (49%), Gaps = 4/132 (3%)
Query: 576 GTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQF 635
GT +Y+APEI L +G+ D W+LG M E L G PPF S P TY I+ + +
Sbjct: 432 GTAEYVAPEIVLNKGHDLSVDIWALGIFMCELLTGSPPFSSTDPMVTYNAILKGLEKWAW 491
Query: 636 PDDIHISYEAEDLIRRLLTHSENRLGRHGGADEIKAHPFFSGVDWNTIR--QVEAPYIPK 693
P ++ EA D++ L + G EI+ H +F D+ R ++ P+IP
Sbjct: 492 PR--FVTKEAIDMMLSLCKYEPTERLGFGDIGEIRHHIWFDNFDFVGFRAHRIRPPFIPS 549
Query: 694 LSSVTDTRFFPT 705
+++ DT F T
Sbjct: 550 VANDIDTSNFDT 561
>Hs4885055 [T] KOG0986 G protein-coupled receptor kinase
Length = 688
Score = 111 bits (278), Expect = 4e-24
Identities = 61/156 (39%), Positives = 91/156 (58%), Gaps = 3/156 (1%)
Query: 345 DDFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLA---G 401
++F+ ++IG+G FGEV +K DTGK+YAMK L K + K ER +L+
Sbjct: 189 NEFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALNERIMLSLVST 248
Query: 402 SDSPWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVI 461
D P++V + Y+F L I++ + GGDL L + +F+E RFY E IL +E +
Sbjct: 249 GDCPFIVCMTYAFHTPDKLCFILDLMNGGDLHYHLSQHGVFSEKEMRFYATEIILGLEHV 308
Query: 462 HKLGFIHRDIKPDNILIDIRGHIKLSDFGLSTGFHK 497
H ++RD+KP NIL+D GH ++SD GL+ F K
Sbjct: 309 HNRFVVYRDLKPANILLDEHGHARISDLGLACDFSK 344
Score = 68.2 bits (165), Expect = 5e-11
Identities = 46/133 (34%), Positives = 69/133 (51%), Gaps = 10/133 (7%)
Query: 572 YSTVGTPDYIAPEIFLYQG--YGQECDWWSLGAIMYECLIGWPPFCSETPQETYR-KIMN 628
+++VGT Y+APE+ L +G Y DW+SLG ++++ L G PF ++ + M
Sbjct: 348 HASVGTHGYMAPEV-LQKGTAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHEIDRMT 406
Query: 629 FEQTLQFPDDIHISYEAEDLIRRLLTHS-ENRLGRHGG-ADEIKAHPFFSGVDWNTI--R 684
++ PD S E + L+ LL RLG HGG + E+K H FF GVDW + +
Sbjct: 407 LTVNVELPDTF--SPELKSLLEGLLQRDVSKRLGCHGGGSQEVKEHSFFKGVDWQHVYLQ 464
Query: 685 QVEAPYIPKLSSV 697
+ P IP V
Sbjct: 465 KYPPPLIPPRGEV 477
>Hs14759411 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 1063
Score = 111 bits (278), Expect = 4e-24
Identities = 61/152 (40%), Positives = 90/152 (59%), Gaps = 3/152 (1%)
Query: 555 TNRQQMQTWRKSRRLMAYSTVGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPF 614
TN + + +R + GTP+YIAPE+ L QGYG+ DWW++G I+YE L+G PF
Sbjct: 21 TNLYEGHIEKDAREFLDKQVCGTPEYIAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPF 80
Query: 615 CSETPQETYRKIMNFEQTLQFPDDIHISYEAEDLIRRLL-THSENRLGRHGGADEIKAHP 673
+TP+E + ++++ + L D + EA+ LI LL T+ RLG GGA E+K H
Sbjct: 81 FGDTPEELFGQVIS-DDILWPEGDEALPTEAQLLISSLLQTNPLVRLGA-GGAFEVKQHS 138
Query: 674 FFSGVDWNTIRQVEAPYIPKLSSVTDTRFFPT 705
FF +DW + + +A +IP L S DT +F T
Sbjct: 139 FFRDLDWTGLLRQKAEFIPHLESEDDTSYFDT 170
>SPBC4C3.11 [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 420
Score = 110 bits (275), Expect = 8e-24
Identities = 53/140 (37%), Positives = 87/140 (61%), Gaps = 1/140 (0%)
Query: 352 VIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDS-PWVVSL 410
+IG G+F +VR K + K YA+K L K + ++++ +V ERD + + P + L
Sbjct: 59 IIGDGSFSKVRRATDKKSWKEYAIKVLDKKYIVKENKVKYVNIERDSMMRLNGFPGISRL 118
Query: 411 YYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKLGFIHRD 470
+++FQD LY ++E P G+L+ + +++ E+ RFY AE + +IE +H G IHRD
Sbjct: 119 FHTFQDDLKLYYVLELAPNGELLQYIKKYRFLDENCVRFYAAEILSSIEYMHSCGIIHRD 178
Query: 471 IKPDNILIDIRGHIKLSDFG 490
+KP+NIL D H+K++DFG
Sbjct: 179 LKPENILFDGNMHVKITDFG 198
Score = 59.3 bits (142), Expect = 2e-08
Identities = 34/122 (27%), Positives = 57/122 (45%), Gaps = 17/122 (13%)
Query: 573 STVGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQT 632
S VGT +Y+APE+ Q + D W+ ++Y+ ++G PPF P ++KIM+ E
Sbjct: 219 SFVGTAEYVAPELLSRQVVSKSSDLWAFACVVYQMIVGSPPFHGSNPNNIFKKIMSLE-- 276
Query: 633 LQFPDDIHISYEAEDLIRRLLTHSENRLGRHGGAD-----EIKAHPFFSGVDWNTIRQVE 687
YE L+ + + L R +D +IK PFF+ + W+ + +
Sbjct: 277 ----------YELPKLLPPDIVPLFSHLFRIQPSDRSTTQQIKQFPFFATITWDNLWTQD 326
Query: 688 AP 689
P
Sbjct: 327 PP 328
>Hs22068916 [T] KOG0696 Serine/threonine protein kinase
Length = 673
Score = 110 bits (274), Expect = 1e-23
Identities = 57/147 (38%), Positives = 88/147 (59%), Gaps = 1/147 (0%)
Query: 346 DFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLA-GSDS 404
DFN + V+GKG+FG+V L ++K T ++YA+K L K + D + E+ VLA
Sbjct: 341 DFNFLMVLGKGSFGKVMLSERKGTDELYAVKILKKDVVIQDDDVECTMVEKRVLALPGKP 400
Query: 405 PWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKL 464
P++ L+ FQ LY +ME++ GGDLM + + F E FY AE + + +
Sbjct: 401 PFLTQLHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGRFKEPHAVFYAAEIAIGLFFLQSK 460
Query: 465 GFIHRDIKPDNILIDIRGHIKLSDFGL 491
G I+RD+K DN+++D GHIK++DFG+
Sbjct: 461 GIIYRDLKLDNVMLDSEGHIKIADFGM 487
Score = 92.0 bits (227), Expect = 3e-18
Identities = 51/122 (41%), Positives = 70/122 (56%), Gaps = 8/122 (6%)
Query: 576 GTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQF 635
GTPDYIAPEI YQ YG+ DWW+ G ++YE L G PF E E ++ IM E + +
Sbjct: 503 GTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMLAGQAPFEGEDEDELFQSIM--EHNVAY 560
Query: 636 PDDIHISYEAEDLIRRLLT-HSENRLG-RHGGADEIKAHPFFSGVDWNTI--RQVEAPYI 691
P +S EA + + L+T H RLG G +IK H FF +DW + ++++ PY
Sbjct: 561 PKS--MSKEAVAICKGLMTKHPGKRLGCGPEGERDIKEHAFFRYIDWEKLERKEIQPPYK 618
Query: 692 PK 693
PK
Sbjct: 619 PK 620
>Hs20127450 [T] KOG0696 Serine/threonine protein kinase
Length = 673
Score = 110 bits (274), Expect = 1e-23
Identities = 57/147 (38%), Positives = 88/147 (59%), Gaps = 1/147 (0%)
Query: 346 DFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLA-GSDS 404
DFN + V+GKG+FG+V L ++K T ++YA+K L K + D + E+ VLA
Sbjct: 341 DFNFLMVLGKGSFGKVMLSERKGTDELYAVKILKKDVVIQDDDVECTMVEKRVLALPGKP 400
Query: 405 PWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKL 464
P++ L+ FQ LY +ME++ GGDLM + + F E FY AE + + +
Sbjct: 401 PFLTQLHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGRFKEPHAVFYAAEIAIGLFFLQSK 460
Query: 465 GFIHRDIKPDNILIDIRGHIKLSDFGL 491
G I+RD+K DN+++D GHIK++DFG+
Sbjct: 461 GIIYRDLKLDNVMLDSEGHIKIADFGM 487
Score = 92.0 bits (227), Expect = 3e-18
Identities = 51/122 (41%), Positives = 70/122 (56%), Gaps = 8/122 (6%)
Query: 576 GTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQF 635
GTPDYIAPEI YQ YG+ DWW+ G ++YE L G PF E E ++ IM E + +
Sbjct: 503 GTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMLAGQAPFEGEDEDELFQSIM--EHNVAY 560
Query: 636 PDDIHISYEAEDLIRRLLT-HSENRLG-RHGGADEIKAHPFFSGVDWNTI--RQVEAPYI 691
P +S EA + + L+T H RLG G +IK H FF +DW + ++++ PY
Sbjct: 561 PKS--MSKEAVAICKGLMTKHPGKRLGCGPEGERDIKEHAFFRYIDWEKLERKEIQPPYK 618
Query: 692 PK 693
PK
Sbjct: 619 PK 620
>SPBC12D12.04c [T] KOG0694 Serine/threonine protein kinase
Length = 1016
Score = 109 bits (273), Expect = 1e-23
Identities = 57/150 (38%), Positives = 94/150 (62%), Gaps = 4/150 (2%)
Query: 345 DDFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDS 404
+DF + V+GKG FG+V L + K ++YA+K L K + D++ K+E+ V ++
Sbjct: 681 EDFTFLSVLGKGNFGKVMLAELKSEKQLYAIKVLKKEFILENDEVESTKSEKRVFLVANR 740
Query: 405 ---PWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVI 461
P++V+L+ FQ +Y +M+F+ GGDLM + I+ + F+ +FY AE LA++
Sbjct: 741 ERHPFLVNLHSCFQTETRIYFVMDFVSGGDLM-LHIQQEQFSRRRAQFYAAEVCLALKYF 799
Query: 462 HKLGFIHRDIKPDNILIDIRGHIKLSDFGL 491
H G I+RD+K DNIL+ GH+K++D+GL
Sbjct: 800 HDNGIIYRDLKLDNILLSPDGHVKVADYGL 829
Score = 101 bits (251), Expect = 5e-21
Identities = 51/141 (36%), Positives = 87/141 (61%), Gaps = 8/141 (5%)
Query: 576 GTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQF 635
GTP+++APEI L Q Y + DWW+ G ++Y+ L+G PF E +E + I++ E +
Sbjct: 845 GTPEFMAPEILLEQQYTRSVDWWAFGVLIYQMLLGQSPFRGEDEEEIFDAILSDEPL--Y 902
Query: 636 PDDIHISYEAEDLIRRLLTHS-ENRLGR-HGGADEIKAHPFFSGVDWNTI--RQVEAPYI 691
P IH+ ++ ++++LLT + RLG A+++ HPFFS ++W+ I ++ + PYI
Sbjct: 903 P--IHMPRDSVSILQQLLTRDPKKRLGSGPNDAEDVMTHPFFSNINWDDIYHKRTQPPYI 960
Query: 692 PKLSSVTDTRFFPTDELENVP 712
P L+S TDT++F + +P
Sbjct: 961 PSLNSPTDTKYFDEEFTRELP 981
>7296166 [T] KOG0614 cGMP-dependent protein kinase
Length = 768
Score = 109 bits (273), Expect = 1e-23
Identities = 53/149 (35%), Positives = 91/149 (60%), Gaps = 2/149 (1%)
Query: 346 DFNSVKVIGKGAFGEVRLVQK--KDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSD 403
D V +G G FG V LV+ +D I+A+K L K + + Q H+ +ER ++ S
Sbjct: 456 DLEVVSTLGIGGFGRVELVKAHHQDRVDIFALKCLKKRHIVDTKQEEHIFSERHIMLSSR 515
Query: 404 SPWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHK 463
SP++ LY +F+D +Y+Y+++E GG++ TML F ++ +F + + A E +H
Sbjct: 516 SPFICRLYRTFRDEKYVYMLLEACMGGEIWTMLRDRGSFEDNAAQFIIGCVLQAFEYLHA 575
Query: 464 LGFIHRDIKPDNILIDIRGHIKLSDFGLS 492
G I+RD+KP+N+++D RG++K+ DFG +
Sbjct: 576 RGIIYRDLKPENLMLDERGYVKIVDFGFA 604
Score = 93.6 bits (231), Expect = 1e-18
Identities = 55/146 (37%), Positives = 82/146 (55%), Gaps = 15/146 (10%)
Query: 576 GTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQF 635
GTP+Y+APEI L +G+ + D+W+LG +++E L G PPF + P +TY I+ + F
Sbjct: 618 GTPEYVAPEIILNKGHDRAVDYWALGILIHELLNGTPPFSAPDPMQTYNLILKGIDMIAF 677
Query: 636 PDDIHISYEAEDLIRRLLTH-SENRLG-RHGGADEIKAHPFFSGVDWNTI--RQVEAPYI 691
P HIS A LI+RL RLG + GG +IK H +F G DW+ + + + P++
Sbjct: 678 PK--HISRWAVQLIKRLCRDVPSERLGYQTGGIQDIKKHKWFLGFDWDGLASQLLIPPFV 735
Query: 692 PKLSSVTDTRFF---------PTDEL 708
++ TD R+F P DEL
Sbjct: 736 RPIAHPTDVRYFDRFPCDLNEPPDEL 761
>Hs5453976 [T] KOG0694 Serine/threonine protein kinase
Length = 706
Score = 108 bits (271), Expect = 2e-23
Identities = 56/148 (37%), Positives = 91/148 (60%), Gaps = 1/148 (0%)
Query: 345 DDFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGS-D 403
+DF K++GKG+FG+V L + K T + +A+K L K + D + E+ VL+ + +
Sbjct: 378 EDFILHKMLGKGSFGKVFLAEFKKTNQFFAIKALKKDVVLMDDDVECTMVEKRVLSLAWE 437
Query: 404 SPWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHK 463
P++ ++ +FQ + L+ +ME+L GGDLM + F FY AE IL ++ +H
Sbjct: 438 HPFLTHMFCTFQTKENLFFVMEYLNGGDLMYHIQSCHKFDLSRATFYAAEIILGLQFLHS 497
Query: 464 LGFIHRDIKPDNILIDIRGHIKLSDFGL 491
G ++RD+K DNIL+D GHIK++DFG+
Sbjct: 498 KGIVYRDLKLDNILLDKDGHIKIADFGM 525
Score = 87.0 bits (214), Expect = 1e-16
Identities = 51/140 (36%), Positives = 73/140 (51%), Gaps = 10/140 (7%)
Query: 576 GTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQF 635
GTPDYIAPEI L Q Y DWWS G ++YE LIG PF + +E + I +
Sbjct: 541 GTPDYIAPEILLGQKYNHSVDWWSFGVLLYEMLIGQSPFHGQDEEELFHSIR--MDNPFY 598
Query: 636 PDDIHISYEAEDLIRRLLTHS-ENRLGRHGGADEIKAHPFFSGVDWNTI--RQVEAPYIP 692
P + EA+DL+ +L E RLG G +I+ HP F ++W + ++++ P+ P
Sbjct: 599 PR--WLEKEAKDLLVKLFVREPEKRLGVRG---DIRQHPLFREINWEELERKEIDPPFRP 653
Query: 693 KLSSVTDTRFFPTDELENVP 712
K+ S D F + L P
Sbjct: 654 KVKSPFDCSNFDKEFLNEKP 673
>Hs21166359 [T] KOG0986 G protein-coupled receptor kinase
Length = 553
Score = 108 bits (271), Expect = 2e-23
Identities = 58/148 (39%), Positives = 89/148 (59%), Gaps = 2/148 (1%)
Query: 347 FNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDSPW 406
F +V+GKG FGEV VQ K+TGK+YA K L K + K E+++L SP+
Sbjct: 191 FTEFRVLGKGGFGEVCAVQVKNTGKMYACKKLDKKRLKKKGGEKMALLEKEILEKVSSPF 250
Query: 407 VVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTR--FYMAECILAIEVIHKL 464
+VSL Y+F+ +L L+M + GGDL + D++R FY A+ + +H+L
Sbjct: 251 IVSLAYAFESKTHLCLVMSLMNGGDLKFHIYNVGTRGLDMSRVIFYSAQIACGMLHLHEL 310
Query: 465 GFIHRDIKPDNILIDIRGHIKLSDFGLS 492
G ++RD+KP+N+L+D G+ +LSD GL+
Sbjct: 311 GIVYRDMKPENVLLDDLGNCRLSDLGLA 338
Score = 56.2 bits (134), Expect = 2e-07
Identities = 40/142 (28%), Positives = 67/142 (47%), Gaps = 7/142 (4%)
Query: 576 GTPDYIAPEIFLYQ-GYGQECDWWSLGAIMYECLIGWPPF--CSETPQETYRKIMNFEQT 632
GT Y+APEI + + Y DW+++G +YE + G PF E + K +
Sbjct: 352 GTNGYMAPEILMEKVSYSYPVDWFAMGCSIYEMVAGRTPFKDYKEKVSKEDLKQRTLQDE 411
Query: 633 LQFPDDIHISYEAEDLIRRLLTHS-ENRLGRHGGADEIKAHPFFSGVDWNTIRQ--VEAP 689
++F D + + EA+D+ R L E RLG +D+ + H FF +++ + +E P
Sbjct: 412 VKFQHD-NFTEEAKDICRLFLAKKPEQRLGSREKSDDPRKHHFFKTINFPRLEAGLIEPP 470
Query: 690 YIPKLSSVTDTRFFPTDELENV 711
++P S V D+ V
Sbjct: 471 FVPDPSVVYAKDIAEIDDFSEV 492
>SPCC320.12c [D] KOG0580 Serine/threonine protein kinase
Length = 384
Score = 108 bits (270), Expect = 3e-23
Identities = 62/146 (42%), Positives = 86/146 (58%)
Query: 347 FNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDSPW 406
F K +GKG FG V L ++K TG I A+KTL KSE+ V+ E ++ +
Sbjct: 118 FEIGKPLGKGKFGRVYLAKEKKTGFIVALKTLHKSELVQSKIEKQVRREIEIQSNLRHKN 177
Query: 407 VVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKLGF 466
++ LY F D + +YLI+EF G+L L R + F+E+V Y+ + A+ +HK
Sbjct: 178 ILRLYGHFHDEKRIYLILEFAGRGELYQHLRRAKRFSEEVASKYIFQMANALSYLHKKHV 237
Query: 467 IHRDIKPDNILIDIRGHIKLSDFGLS 492
IHRDIKP+NIL+ I G IKLSDFG S
Sbjct: 238 IHRDIKPENILLGIDGEIKLSDFGWS 263
Score = 54.3 bits (129), Expect = 7e-07
Identities = 35/101 (34%), Positives = 56/101 (54%), Gaps = 10/101 (9%)
Query: 576 GTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQE-TYRKIMNFEQTLQ 634
GT DY+ PE+ + + ++ D WSLG + YE L+G PPF + TY++I + L+
Sbjct: 276 GTLDYLPPEMVEGKEHTEKVDLWSLGVLTYEFLVGAPPFEDMSGHSATYKRIAKVD--LK 333
Query: 635 FPDDIHISYEAEDLIRRLLTHS-ENRLGRHGGADEIKAHPF 674
P + +A DLI RLL H+ E R+ +++ HP+
Sbjct: 334 IPS--FVPPDARDLISRLLQHNPEKRM----SLEQVMRHPW 368
>Hs13384594 [T] KOG0696 Serine/threonine protein kinase
Length = 697
Score = 108 bits (270), Expect = 3e-23
Identities = 55/152 (36%), Positives = 90/152 (59%), Gaps = 6/152 (3%)
Query: 346 DFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLA----- 400
DF+ + V+GKG+FG+V L +++ + ++YA+K L K + D + E+ VLA
Sbjct: 350 DFSFLMVLGKGSFGKVMLAERRGSDELYAIKILKKDVIVQDDDVDCTLVEKRVLALGGRG 409
Query: 401 -GSDSPWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIE 459
G ++ L+ +FQ LY +ME++ GGDLM + + F E FY AE + +
Sbjct: 410 PGGRPHFLTQLHSTFQTPDRLYFVMEYVTGGDLMYHIQQLGKFKEPHAAFYAAEIAIGLF 469
Query: 460 VIHKLGFIHRDIKPDNILIDIRGHIKLSDFGL 491
+H G I+RD+K DN+++D GHIK++DFG+
Sbjct: 470 FLHNQGIIYRDLKLDNVMLDAEGHIKITDFGM 501
Score = 99.4 bits (246), Expect = 2e-20
Identities = 53/116 (45%), Positives = 69/116 (58%), Gaps = 6/116 (5%)
Query: 576 GTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQF 635
GTPDYIAPEI YQ YG+ DWWS G ++YE L G PPF E +E ++ IM EQT+ +
Sbjct: 517 GTPDYIAPEIIAYQPYGKSVDWWSFGVLLYEMLAGQPPFDGEDEEELFQAIM--EQTVTY 574
Query: 636 PDDIHISYEAEDLIRRLLT-HSENRLGR-HGGADEIKAHPFFSGVDWNTIRQVEAP 689
P +S EA + + LT H RLG G I+AH FF +DW + ++E P
Sbjct: 575 PKS--LSREAVAICKGFLTKHPGKRLGSGPDGEPTIRAHGFFRWIDWERLERLEIP 628
>7303915 [T] KOG0694 Serine/threonine protein kinase
Length = 590
Score = 107 bits (268), Expect = 5e-23
Identities = 54/150 (36%), Positives = 95/150 (63%), Gaps = 4/150 (2%)
Query: 345 DDFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDS 404
D+F + V+G+G FG+V L Q + + YA+K L K ++ +D++ + +E+ + +++
Sbjct: 261 DNFRLLSVLGRGHFGKVILSQLRSNNQYYAIKALKKGDIIARDEVESLLSEKRIFEVANA 320
Query: 405 ---PWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVI 461
P++V+LY FQ Q++ +ME+ GGDLM M I +F E FY A +L ++ +
Sbjct: 321 MRHPFLVNLYSCFQTEQHVCFVMEYAAGGDLM-MHIHTDVFLEPRAVFYAACVVLGLQYL 379
Query: 462 HKLGFIHRDIKPDNILIDIRGHIKLSDFGL 491
H+ I+RD+K DN+L+D G++K++DFGL
Sbjct: 380 HENKIIYRDLKLDNLLLDTEGYVKIADFGL 409
Score = 81.3 bits (199), Expect = 5e-15
Identities = 44/132 (33%), Positives = 77/132 (58%), Gaps = 8/132 (6%)
Query: 576 GTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQF 635
GTP+++APE+ Y + DWW LG +++E L+G PF + +E + I+N E +++
Sbjct: 425 GTPEFLAPEVLTETSYTRAVDWWGLGVLIFEMLVGESPFPGDDEEEVFDSIVNDE--VRY 482
Query: 636 PDDIHISYEAEDLIRRLL-THSENRLG-RHGGADEIKAHPFFSGVDWN--TIRQVEAPYI 691
P +S EA ++RRLL + E RLG A+++K FF + W+ +R+V+ P++
Sbjct: 483 PR--FLSLEAIAVMRRLLRKNPERRLGSSERDAEDVKKQAFFRSIVWDDLLLRKVKPPFV 540
Query: 692 PKLSSVTDTRFF 703
P ++ + D F
Sbjct: 541 PTINHLEDVSNF 552
>7303914 [T] KOG0694 Serine/threonine protein kinase
Length = 1284
Score = 107 bits (268), Expect = 5e-23
Identities = 54/150 (36%), Positives = 95/150 (63%), Gaps = 4/150 (2%)
Query: 345 DDFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDS 404
D+F + V+G+G FG+V L Q + + YA+K L K ++ +D++ + +E+ + +++
Sbjct: 955 DNFRLLSVLGRGHFGKVILSQLRSNNQYYAIKALKKGDIIARDEVESLLSEKRIFEVANA 1014
Query: 405 ---PWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVI 461
P++V+LY FQ Q++ +ME+ GGDLM M I +F E FY A +L ++ +
Sbjct: 1015 MRHPFLVNLYSCFQTEQHVCFVMEYAAGGDLM-MHIHTDVFLEPRAVFYAACVVLGLQYL 1073
Query: 462 HKLGFIHRDIKPDNILIDIRGHIKLSDFGL 491
H+ I+RD+K DN+L+D G++K++DFGL
Sbjct: 1074 HENKIIYRDLKLDNLLLDTEGYVKIADFGL 1103
Score = 81.3 bits (199), Expect = 5e-15
Identities = 44/132 (33%), Positives = 77/132 (58%), Gaps = 8/132 (6%)
Query: 576 GTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQF 635
GTP+++APE+ Y + DWW LG +++E L+G PF + +E + I+N E +++
Sbjct: 1119 GTPEFLAPEVLTETSYTRAVDWWGLGVLIFEMLVGESPFPGDDEEEVFDSIVNDE--VRY 1176
Query: 636 PDDIHISYEAEDLIRRLL-THSENRLG-RHGGADEIKAHPFFSGVDWN--TIRQVEAPYI 691
P +S EA ++RRLL + E RLG A+++K FF + W+ +R+V+ P++
Sbjct: 1177 PR--FLSLEAIAVMRRLLRKNPERRLGSSERDAEDVKKQAFFRSIVWDDLLLRKVKPPFV 1234
Query: 692 PKLSSVTDTRFF 703
P ++ + D F
Sbjct: 1235 PTINHLEDVSNF 1246
>Hs4506073 [T] KOG0694 Serine/threonine protein kinase
Length = 942
Score = 107 bits (267), Expect = 7e-23
Identities = 52/150 (34%), Positives = 98/150 (64%), Gaps = 4/150 (2%)
Query: 345 DDFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDS 404
+DF + V+G+G FG+V L + + +G+++A+K L K ++ +D++ + E+ +LA S
Sbjct: 613 EDFKFLAVLGRGHFGKVLLSEFRPSGELFAIKALKKGDIVARDEVESLMCEKRILAAVTS 672
Query: 405 ---PWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVI 461
P++V+L+ FQ +++ +ME+ GGDLM + I +F+E FY A +L ++ +
Sbjct: 673 AGHPFLVNLFGCFQTPEHVCFVMEYSAGGDLM-LHIHSDVFSEPRAIFYSACVVLGLQFL 731
Query: 462 HKLGFIHRDIKPDNILIDIRGHIKLSDFGL 491
H+ ++RD+K DN+L+D G++K++DFGL
Sbjct: 732 HEHKIVYRDLKLDNLLLDTEGYVKIADFGL 761
Score = 87.4 bits (215), Expect = 7e-17
Identities = 49/141 (34%), Positives = 78/141 (54%), Gaps = 8/141 (5%)
Query: 576 GTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQF 635
GTP+++APE+ Y + DWW LG ++YE L+G PF + +E + I+N E +++
Sbjct: 777 GTPEFLAPEVLTDTSYTRAVDWWGLGVLLYEMLVGESPFPGDDEEEVFDSIVNDE--VRY 834
Query: 636 PDDIHISYEAEDLIRRLLTHS-ENRLG-RHGGADEIKAHPFFSGVDWNTI--RQVEAPYI 691
P +S EA ++RRLL + E RLG A+++K PFF + W + R++ P++
Sbjct: 835 PR--FLSAEAIGIMRRLLRRNPERRLGSSERDAEDVKKQPFFRTLGWEALLARRLPPPFV 892
Query: 692 PKLSSVTDTRFFPTDELENVP 712
P LS TD F + P
Sbjct: 893 PTLSGRTDVSNFDEEFTGEAP 913
>Hs14758219 [T] KOG0694 Serine/threonine protein kinase
Length = 942
Score = 107 bits (267), Expect = 7e-23
Identities = 52/150 (34%), Positives = 98/150 (64%), Gaps = 4/150 (2%)
Query: 345 DDFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDS 404
+DF + V+G+G FG+V L + + +G+++A+K L K ++ +D++ + E+ +LA S
Sbjct: 613 EDFKFLAVLGRGHFGKVLLSEFRPSGELFAIKALKKGDIVARDEVESLMCEKRILAAVTS 672
Query: 405 ---PWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVI 461
P++V+L+ FQ +++ +ME+ GGDLM + I +F+E FY A +L ++ +
Sbjct: 673 AGHPFLVNLFGCFQTPEHVCFVMEYSAGGDLM-LHIHSDVFSEPRAIFYSACVVLGLQFL 731
Query: 462 HKLGFIHRDIKPDNILIDIRGHIKLSDFGL 491
H+ ++RD+K DN+L+D G++K++DFGL
Sbjct: 732 HEHKIVYRDLKLDNLLLDTEGYVKIADFGL 761
Score = 87.4 bits (215), Expect = 7e-17
Identities = 49/141 (34%), Positives = 78/141 (54%), Gaps = 8/141 (5%)
Query: 576 GTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQF 635
GTP+++APE+ Y + DWW LG ++YE L+G PF + +E + I+N E +++
Sbjct: 777 GTPEFLAPEVLTDTSYTRAVDWWGLGVLLYEMLVGESPFPGDDEEEVFDSIVNDE--VRY 834
Query: 636 PDDIHISYEAEDLIRRLLTHS-ENRLG-RHGGADEIKAHPFFSGVDWNTI--RQVEAPYI 691
P +S EA ++RRLL + E RLG A+++K PFF + W + R++ P++
Sbjct: 835 PR--FLSAEAIGIMRRLLRRNPERRLGSSERDAEDVKKQPFFRTLGWEALLARRLPPPFV 892
Query: 692 PKLSSVTDTRFFPTDELENVP 712
P LS TD F + P
Sbjct: 893 PTLSGRTDVSNFDEEFTGEAP 913
>YBL105c [T] KOG0694 Serine/threonine protein kinase
Length = 1151
Score = 107 bits (266), Expect = 9e-23
Identities = 58/154 (37%), Positives = 92/154 (59%), Gaps = 12/154 (7%)
Query: 345 DDFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVL---AG 401
D+F +KV+GKG FG+V L + K+T ++ A+K L K + + +AE+ V
Sbjct: 822 DNFVLLKVLGKGNFGKVILSKSKNTDRLCAIKVLKKDNIIQNHDIESARAEKKVFLLATK 881
Query: 402 SDSPWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVT----RFYMAECILA 457
+ P++ +LY SFQ +Y MEF+ GGDLM W + + ++ +FY AE +LA
Sbjct: 882 TKHPFLTNLYCSFQTENRIYFAMEFIGGGDLM-----WHVQNQRLSVRRAKFYAAEVLLA 936
Query: 458 IEVIHKLGFIHRDIKPDNILIDIRGHIKLSDFGL 491
++ H G I+RD+K +NIL+ GHIK++D+GL
Sbjct: 937 LKYFHDNGVIYRDLKLENILLTPEGHIKIADYGL 970
Score = 78.2 bits (191), Expect = 4e-14
Identities = 46/132 (34%), Positives = 73/132 (54%), Gaps = 8/132 (6%)
Query: 576 GTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQF 635
GTP+++APEI Q Y + DWW+ G ++Y+ L+ PF + E + I+ E +
Sbjct: 986 GTPEFMAPEILKEQEYTKAVDWWAFGVLLYQMLLCQSPFSGDDEDEVFNAILTDEPL--Y 1043
Query: 636 PDDIHISYEAEDLIRRLLTHS-ENRLGR-HGGADEIKAHPFFSGVDWNTI--RQVEAPYI 691
P I ++ E + + LLT E RLG ADE+ PFF ++++ I +V+ PYI
Sbjct: 1044 P--IDMAGEIVQIFQGLLTKDPEKRLGAGPRDADEVMEEPFFRNINFDDILNLRVKPPYI 1101
Query: 692 PKLSSVTDTRFF 703
P++ S DT +F
Sbjct: 1102 PEIKSPEDTSYF 1113
>7302050 [T] KOG0986 G protein-coupled receptor kinase
Length = 714
Score = 106 bits (265), Expect = 1e-22
Identities = 56/149 (37%), Positives = 87/149 (57%), Gaps = 3/149 (2%)
Query: 347 FNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDSPW 406
F +V+GKG FGEV Q + TGK+YA K L K + + + V E+ +L +SP+
Sbjct: 309 FRMYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGESMVLIEKQILQKINSPF 368
Query: 407 VVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRW---QIFTEDVTRFYMAECILAIEVIHK 463
VV+L Y+++ L L++ + GGDL + F + RFY AE ++ +HK
Sbjct: 369 VVNLAYAYETKDALCLVLTIMNGGDLKFHIYNMGGEPGFELERARFYAAEVACGLQHLHK 428
Query: 464 LGFIHRDIKPDNILIDIRGHIKLSDFGLS 492
G ++RD KP+NIL+D GH+++SD GL+
Sbjct: 429 QGIVYRDCKPENILLDDHGHVRISDLGLA 457
Score = 58.2 bits (139), Expect = 5e-08
Identities = 47/160 (29%), Positives = 75/160 (46%), Gaps = 17/160 (10%)
Query: 570 MAYSTVGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNF 629
M VGT Y+APE+ + Y DW+S G ++YE + G PF +E ++
Sbjct: 465 MVRGRVGTVGYMAPEVIDNEKYAFSPDWFSFGCLLYEMIEGQAPF--RMRKEKVKREEVD 522
Query: 630 EQTLQFPDDIHISY--EAEDLIRRLLTHS-ENRLG-RHG--GADEIKAHPFFSGVDWNTI 683
+ + P+ + EA+ + ++LL S + RLG R+G G ++ AHPFF N
Sbjct: 523 RRVKEDPEKYSSKFNDEAKSMCQQLLAKSIKQRLGCRNGRMGGQDVMAHPFFHSTQLNWR 582
Query: 684 R----QVEAPYIPK-----LSSVTDTRFFPTDELENVPDS 714
R +E P++P V D F T + N+ +S
Sbjct: 583 RLEAGMLEPPFVPDPHAVYAKDVLDIEQFSTVKGVNIDES 622
>Hs5453974 [T] KOG0694 Serine/threonine protein kinase
Length = 984
Score = 105 bits (263), Expect = 2e-22
Identities = 52/149 (34%), Positives = 94/149 (62%), Gaps = 4/149 (2%)
Query: 346 DFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDS- 404
DF V+G+G FG+V L + K+T +++A+K L K ++ +D++ + E+ + +S
Sbjct: 656 DFRCCAVLGRGHFGKVLLAEYKNTNEMFAIKALKKGDIVARDEVDSLMCEKRIFETVNSV 715
Query: 405 --PWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIH 462
P++V+L+ FQ +++ +ME+ GGDLM M I +F+E FY A +L ++ +H
Sbjct: 716 RHPFLVNLFACFQTKEHVCFVMEYAAGGDLM-MHIHTDVFSEPRAVFYAACVVLGLQYLH 774
Query: 463 KLGFIHRDIKPDNILIDIRGHIKLSDFGL 491
+ ++RD+K DN+L+D G +K++DFGL
Sbjct: 775 EHKIVYRDLKLDNLLLDTEGFVKIADFGL 803
Score = 90.9 bits (224), Expect = 7e-18
Identities = 49/141 (34%), Positives = 80/141 (55%), Gaps = 8/141 (5%)
Query: 576 GTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQF 635
GTP+++APE+ Y + DWW LG ++YE L+G PF + +E + I+N E +++
Sbjct: 819 GTPEFLAPEVLTETSYTRAVDWWGLGVLIYEMLVGESPFPGDDEEEVFDSIVNDE--VRY 876
Query: 636 PDDIHISYEAEDLIRRLLTHS-ENRLG-RHGGADEIKAHPFFSGVDWNTI--RQVEAPYI 691
P +S EA ++RRLL + E RLG A+++K HPFF +DW+ + ++V+ P+I
Sbjct: 877 PR--FLSTEAISIMRRLLRRNPERRLGASEKDAEDVKKHPFFRLIDWSALMDKKVKPPFI 934
Query: 692 PKLSSVTDTRFFPTDELENVP 712
P + D F + P
Sbjct: 935 PTIRGREDVSNFDDEFTSEAP 955
>Hs14735945 [T] KOG0694 Serine/threonine protein kinase
Length = 676
Score = 103 bits (258), Expect = 8e-22
Identities = 55/142 (38%), Positives = 86/142 (59%), Gaps = 1/142 (0%)
Query: 351 KVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLA-GSDSPWVVS 409
KV+GKG+FG+V L + K G+ +A+K L K + D + E+ VL +++P++
Sbjct: 353 KVLGKGSFGKVLLGELKGRGEYFAIKALKKDVVLIDDDVECTMVEKRVLTLAAENPFLTH 412
Query: 410 LYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKLGFIHR 469
L +FQ +L+ +MEFL GGDLM + F FY AE + ++ +H G I+R
Sbjct: 413 LICTFQTKDHLFFVMEFLNGGDLMYHIQDKGRFELYRATFYAAEIMCGLQFLHSKGIIYR 472
Query: 470 DIKPDNILIDIRGHIKLSDFGL 491
D+K DN+L+D GHIK++DFG+
Sbjct: 473 DLKLDNVLLDRDGHIKIADFGM 494
Score = 82.8 bits (203), Expect = 2e-15
Identities = 49/135 (36%), Positives = 69/135 (50%), Gaps = 8/135 (5%)
Query: 576 GTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQF 635
GTPDYIAPEI Y DWWS G ++YE LIG PF + E + I T +
Sbjct: 510 GTPDYIAPEILQGLKYTFSVDWWSFGVLLYEMLIGQSPFHGDDEDELFESIR--VDTPHY 567
Query: 636 PDDIHISYEAEDLIRRLLTHSENRLGRHGGADEIKAHPFFSGVDWNTI--RQVEAPYIPK 693
P I+ E++D++ +L + R G IK HPFF ++W + R++E P+ PK
Sbjct: 568 PR--WITKESKDILEKLFEREPTK--RLGVTGNIKIHPFFKTINWTLLEKRRLEPPFRPK 623
Query: 694 LSSVTDTRFFPTDEL 708
+ S D F + L
Sbjct: 624 VKSPRDYSNFDQEFL 638
>CE07156 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 392
Score = 103 bits (258), Expect = 8e-22
Identities = 58/152 (38%), Positives = 90/152 (59%), Gaps = 8/152 (5%)
Query: 345 DDFNSVKVIGKGAFGEVRLVQKK---DTGKIYAMKTLLKSEMY-NKDQLAHVKAERDVLA 400
+DF +K IG GA+GEV V+K DT IYAMK + K M +KD + H E +L
Sbjct: 27 EDFEILKHIGSGAYGEVAAVRKLNGCDTETIYAMKVMEKRRMSKHKDMVEH---EWKILT 83
Query: 401 GSDSPWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEV 460
+P+ + + YSFQ ++L +M F GGD++TM+ + E+ FY+ E + I
Sbjct: 84 TIHNPFFMKMSYSFQTKRHLVFVMPFAGGGDMLTMMEN-ECLIEESAHFYLCELVEGIGY 142
Query: 461 IHKLGFIHRDIKPDNILIDIRGHIKLSDFGLS 492
+H+ +HRD+K +N+LI GH+ ++D+GLS
Sbjct: 143 LHEKHIVHRDVKLENLLIGNDGHLMITDYGLS 174
Score = 42.7 bits (99), Expect = 0.002
Identities = 37/144 (25%), Positives = 53/144 (36%), Gaps = 21/144 (14%)
Query: 575 VGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPF----CSETPQETYRKIMNFE 630
+GT +APE+ L + YG CDWW++G + F E T +K
Sbjct: 188 IGTRHTMAPEVHLEKKYGTSCDWWAVGITYCDMRSDKAVFDGADSKEYSDSTAKKRPRLP 247
Query: 631 QTLQFPDDIHISYEAEDLIRRLLTHS-ENRLGR-HGGADEIKAHPFFSGVDWNTIRQVEA 688
+ L S + +L+ RLG G +KAH F GV W +
Sbjct: 248 KVL--------SPRERGFVNKLIVRDPTQRLGNGPDGTATVKAHDMFKGVVWEDV----- 294
Query: 689 PYIPKLSSVTDTRFFPTDELENVP 712
+ K S + F T N P
Sbjct: 295 --LAKKSKSDNYSVFATHNFGNRP 316
>CE27166 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 270
Score = 103 bits (257), Expect = 1e-21
Identities = 45/105 (42%), Positives = 72/105 (67%)
Query: 388 QLAHVKAERDVLAGSDSPWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVT 447
Q HV E+ VL P++V +Y S +DS +LY+IMEF+PGG++ + L + F+ +
Sbjct: 3 QTQHVHNEKRVLLQLKHPFIVKMYASEKDSNHLYMIMEFVPGGEMFSYLRASRSFSNSMA 62
Query: 448 RFYMAECILAIEVIHKLGFIHRDIKPDNILIDIRGHIKLSDFGLS 492
RFY +E + A+E IH LG ++RD+KP+N+++ GHIK++DFG +
Sbjct: 63 RFYASEIVCALEYIHSLGIVYRDLKPENLMLSKEGHIKMADFGFA 107
Score = 91.3 bits (225), Expect = 5e-18
Identities = 57/165 (34%), Positives = 87/165 (52%), Gaps = 12/165 (7%)
Query: 543 NTMLVDAIHLTMTNRQQMQTWRKSRRLMAYSTVGTPDYIAPEIFLYQGYGQECDWWSLGA 602
N ML H+ M + + K R Y+ GTPDY+APE G+ + DWW+LG
Sbjct: 90 NLMLSKEGHIKMADFG----FAKELRDRTYTICGTPDYLAPESLARTGHNKGVDWWALGI 145
Query: 603 IMYECLIGWPPFCSETPQETYRKIMNFEQTLQFPDDIHISYEAEDLIRRLL-THSENRLG 661
++YE ++G PPF +T E Y I+ E L+FP +++ A+DL+++LL R+G
Sbjct: 146 LIYEMMVGKPPFRGKTTSEIYDAII--EHKLKFPRSFNLA--AKDLVKKLLEVDRTQRIG 201
Query: 662 -RHGGADEIKAHPFFSGVDWNTI--RQVEAPYIPKLSSVTDTRFF 703
G ++K H +F V+W+ +VE P +P L DT F
Sbjct: 202 CMKNGTQDVKDHKWFEKVNWDDTLHLRVEPPIVPTLYHPGDTGNF 246
>CE19898 [T] KOG0614 cGMP-dependent protein kinase
Length = 737
Score = 103 bits (257), Expect = 1e-21
Identities = 50/141 (35%), Positives = 85/141 (59%), Gaps = 1/141 (0%)
Query: 353 IGKGAFGEVRLV-QKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDSPWVVSLY 411
+G G FG V LV D K +A+K L K + + Q H+ AER+++ + + W+V LY
Sbjct: 432 LGVGGFGRVELVCVNGDKAKTFALKALKKKHIVDTRQQEHIFAERNIMMETSTDWIVKLY 491
Query: 412 YSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKLGFIHRDI 471
+F+D +++Y+++E GG+L T L F + RFY+A + +E +H+ ++RD+
Sbjct: 492 KTFRDQKFVYMLLEVCLGGELWTTLRDRGHFDDYTARFYVACVLEGLEYLHRKNIVYRDL 551
Query: 472 KPDNILIDIRGHIKLSDFGLS 492
KP+N L+ G++KL DFG +
Sbjct: 552 KPENCLLANTGYLKLVDFGFA 572
Score = 87.8 bits (216), Expect = 6e-17
Identities = 47/132 (35%), Positives = 76/132 (56%), Gaps = 5/132 (3%)
Query: 576 GTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQF 635
GTP+Y++PEI L +G+ Q D+W+LG + E ++G PPF + P +TY I+ L+
Sbjct: 586 GTPEYVSPEIILNKGHDQAADYWALGIYICELMLGRPPFQASDPMKTYTLILKGVDALEI 645
Query: 636 PDDIHISYEAEDLIRRLLTHSE-NRLGR-HGGADEIKAHPFFSGVDWNTIRQ--VEAPYI 691
P+ I A L+++L + RLG GG ++I+ H +F G DW +R ++ P +
Sbjct: 646 PNR-RIGKTATALVKKLCRDNPGERLGSGSGGVNDIRKHRWFMGFDWEGLRSRTLKPPIL 704
Query: 692 PKLSSVTDTRFF 703
PK+S+ D F
Sbjct: 705 PKVSNPADVTNF 716
>CE19897 [T] KOG0614 cGMP-dependent protein kinase
Length = 780
Score = 103 bits (257), Expect = 1e-21
Identities = 50/141 (35%), Positives = 85/141 (59%), Gaps = 1/141 (0%)
Query: 353 IGKGAFGEVRLV-QKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDSPWVVSLY 411
+G G FG V LV D K +A+K L K + + Q H+ AER+++ + + W+V LY
Sbjct: 475 LGVGGFGRVELVCVNGDKAKTFALKALKKKHIVDTRQQEHIFAERNIMMETSTDWIVKLY 534
Query: 412 YSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKLGFIHRDI 471
+F+D +++Y+++E GG+L T L F + RFY+A + +E +H+ ++RD+
Sbjct: 535 KTFRDQKFVYMLLEVCLGGELWTTLRDRGHFDDYTARFYVACVLEGLEYLHRKNIVYRDL 594
Query: 472 KPDNILIDIRGHIKLSDFGLS 492
KP+N L+ G++KL DFG +
Sbjct: 595 KPENCLLANTGYLKLVDFGFA 615
Score = 87.8 bits (216), Expect = 6e-17
Identities = 47/132 (35%), Positives = 76/132 (56%), Gaps = 5/132 (3%)
Query: 576 GTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQF 635
GTP+Y++PEI L +G+ Q D+W+LG + E ++G PPF + P +TY I+ L+
Sbjct: 629 GTPEYVSPEIILNKGHDQAADYWALGIYICELMLGRPPFQASDPMKTYTLILKGVDALEI 688
Query: 636 PDDIHISYEAEDLIRRLLTHSE-NRLGR-HGGADEIKAHPFFSGVDWNTIRQ--VEAPYI 691
P+ I A L+++L + RLG GG ++I+ H +F G DW +R ++ P +
Sbjct: 689 PNR-RIGKTATALVKKLCRDNPGERLGSGSGGVNDIRKHRWFMGFDWEGLRSRTLKPPIL 747
Query: 692 PKLSSVTDTRFF 703
PK+S+ D F
Sbjct: 748 PKVSNPADVTNF 759
>Hs22066167 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 147
Score = 103 bits (256), Expect = 1e-21
Identities = 50/107 (46%), Positives = 72/107 (66%)
Query: 385 NKDQLAHVKAERDVLAGSDSPWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTE 444
N AH KAE ++L P++V L Y+FQ LYLI+E+L GG+L L R IF E
Sbjct: 5 NAKDTAHTKAEWNILEEVRHPFIVDLTYAFQTGGKLYLILEYLSGGELFMQLEREGIFME 64
Query: 445 DVTRFYMAECILAIEVIHKLGFIHRDIKPDNILIDIRGHIKLSDFGL 491
D FY+AE +A+ +H+ G I+RD+KP+NI+++ +GH+KL+DFGL
Sbjct: 65 DTACFYLAEISMALGHLHQKGIIYRDLKPENIILNHQGHMKLTDFGL 111
>Hs7662170 [R] KOG0611 Predicted serine/threonine protein kinase
Length = 661
Score = 102 bits (253), Expect = 3e-21
Identities = 43/147 (29%), Positives = 92/147 (62%)
Query: 351 KVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDSPWVVSL 410
+ +GKG +G+V+ ++ +G++ A+K++ K ++ ++ + H++ E ++++ + P ++S+
Sbjct: 59 ETLGKGTYGKVKRATERFSGRVVAIKSIRKDKIKDEQDMVHIRREIEIMSSLNHPHIISI 118
Query: 411 YYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKLGFIHRD 470
Y F++ + +IME+ G+L + + +E TR + + + A+ HK G +HRD
Sbjct: 119 YEVFENKDKIVIIMEYASKGELYDYISERRRLSERETRHFFRQIVSAVHYCHKNGVVHRD 178
Query: 471 IKPDNILIDIRGHIKLSDFGLSTGFHK 497
+K +NIL+D +IK++DFGLS + K
Sbjct: 179 LKLENILLDDNCNIKIADFGLSNLYQK 205
Score = 37.7 bits (86), Expect = 0.066
Identities = 25/89 (28%), Positives = 44/89 (49%), Gaps = 3/89 (3%)
Query: 543 NTMLVDAIHLTMTNRQQMQTWRKSRRLMAYSTVGTPDYIAPEIFLYQGY-GQECDWWSLG 601
N +L D ++ + + ++K + L + G+P Y +PEI + Y G E D W+LG
Sbjct: 183 NILLDDNCNIKIADFGLSNLYQKDKFLQTFC--GSPLYASPEIVNGRPYRGPEVDSWALG 240
Query: 602 AIMYECLIGWPPFCSETPQETYRKIMNFE 630
++Y + G PF + R+I + E
Sbjct: 241 VLLYTLVYGTMPFDGFDHKNLIRQISSGE 269
>Hs5453970 [T] KOG0694 Serine/threonine protein kinase
Length = 676
Score = 102 bits (253), Expect = 3e-21
Identities = 55/142 (38%), Positives = 85/142 (59%), Gaps = 1/142 (0%)
Query: 351 KVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLA-GSDSPWVVS 409
KV+GKG+FG+V L + K G+ A+K L K + D + E+ VL +++P++
Sbjct: 353 KVLGKGSFGKVLLGELKGRGEYSAIKALKKDVVLIDDDVECTMVEKRVLTLAAENPFLTH 412
Query: 410 LYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKLGFIHR 469
L +FQ +L+ +MEFL GGDLM + F FY AE + ++ +H G I+R
Sbjct: 413 LICTFQTKDHLFFVMEFLNGGDLMYHIQDKGRFELYRATFYAAEIMCGLQFLHSKGIIYR 472
Query: 470 DIKPDNILIDIRGHIKLSDFGL 491
D+K DN+L+D GHIK++DFG+
Sbjct: 473 DLKLDNVLLDRDGHIKIADFGM 494
Score = 82.8 bits (203), Expect = 2e-15
Identities = 49/135 (36%), Positives = 69/135 (50%), Gaps = 8/135 (5%)
Query: 576 GTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQF 635
GTPDYIAPEI Y DWWS G ++YE LIG PF + E + I T +
Sbjct: 510 GTPDYIAPEILQGLKYTFSVDWWSFGVLLYEMLIGQSPFHGDDEDELFESIR--VDTPHY 567
Query: 636 PDDIHISYEAEDLIRRLLTHSENRLGRHGGADEIKAHPFFSGVDWNTI--RQVEAPYIPK 693
P I+ E++D++ +L + R G IK HPFF ++W + R++E P+ PK
Sbjct: 568 PR--WITKESKDILEKLFEREPTK--RLGMTGNIKIHPFFKTINWTLLEKRRLEPPFRPK 623
Query: 694 LSSVTDTRFFPTDEL 708
+ S D F + L
Sbjct: 624 VKSPRDYSNFDQEFL 638
>CE18699 [T] KOG0694 Serine/threonine protein kinase
Length = 1018
Score = 102 bits (253), Expect = 3e-21
Identities = 54/150 (36%), Positives = 91/150 (60%), Gaps = 4/150 (2%)
Query: 345 DDFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAER---DVLAG 401
+ F + V+G+G FG+V L Q T YA+K L K ++ +D++ + E+ +V +
Sbjct: 688 EQFRLISVLGRGHFGKVILSQHNPTSNYYALKVLKKGDILGRDEVESLMVEKRIFEVSSR 747
Query: 402 SDSPWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVI 461
+ P++V+L FQ +++++ ME+ GGDLM I +F E FY A +L ++ +
Sbjct: 748 ARHPFLVNLNGCFQTNEHVFFCMEYSMGGDLMRH-IHDDVFDEVRGCFYAACVVLGLDFL 806
Query: 462 HKLGFIHRDIKPDNILIDIRGHIKLSDFGL 491
HK I+RDIK DN+L+D G++K++DFGL
Sbjct: 807 HKHNIIYRDIKLDNLLLDREGYVKIADFGL 836
Score = 75.5 bits (184), Expect = 3e-13
Identities = 42/134 (31%), Positives = 74/134 (54%), Gaps = 10/134 (7%)
Query: 576 GTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQF 635
GTP+++APE+ Y + DWW LG +++E L+G PPF + +E + I++ + +++
Sbjct: 852 GTPEFLAPEVLSDSSYTRAIDWWGLGVLIFEMLVGEPPFSGDDEEEIFDSIIS--EDVRY 909
Query: 636 PDDIHISYEAEDLIRRLLTH-SENRLG-RHGGADEIKAHPFFSGVDWN----TIRQVEAP 689
P ++S E+ ++RRLL E RLG A++IK FF + W R++ P
Sbjct: 910 PR--YLSVESIAIMRRLLRKVPEKRLGYGERDAEDIKIQRFFRHISWEWDKLLNREIRPP 967
Query: 690 YIPKLSSVTDTRFF 703
+ P++ + D F
Sbjct: 968 FQPQIRNPEDVSNF 981
>CE01554 [T] KOG0986 G protein-coupled receptor kinase
Length = 642
Score = 102 bits (253), Expect = 3e-21
Identities = 55/148 (37%), Positives = 86/148 (57%), Gaps = 2/148 (1%)
Query: 347 FNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDSPW 406
F +V+GKG FGEV Q + +GK+YA+K L K + + E+ +L +SP+
Sbjct: 203 FRLYRVLGKGGFGEVCACQVRASGKMYALKKLEKKRVKKRHAETLSLNEKQILQRINSPF 262
Query: 407 VVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQI--FTEDVTRFYMAECILAIEVIHKL 464
VVSL Y+++ L L++ + GGDL L F E +FY AE L ++ +H
Sbjct: 263 VVSLAYAYETKDALCLVLTLMNGGDLKFHLYNLMPGGFDEKRVQFYAAEITLGLQHLHSE 322
Query: 465 GFIHRDIKPDNILIDIRGHIKLSDFGLS 492
++RD+KP+NIL+D GH+++SD GL+
Sbjct: 323 RILYRDLKPENILLDDFGHVRISDLGLA 350
Score = 60.8 bits (146), Expect = 7e-09
Identities = 42/119 (35%), Positives = 57/119 (47%), Gaps = 9/119 (7%)
Query: 575 VGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQ 634
VGT Y+APEI + Y DWW +G ++YE + G PF + ++ + Q
Sbjct: 363 VGTVGYMAPEIVKNERYSYGVDWWGVGCLIYEMIEGKAPFRQRKEKVKREEVERRVREDQ 422
Query: 635 FPDDIHISYEAEDLIRRLLTHSE-------NRLGR-HGGADEIKAHPFFSGVDWNTIRQ 685
S A L R LL H E R+GR GA+EI+AHPFF+ D T R+
Sbjct: 423 EKYSEKFSEAARTLCRGLL-HKEPGFRLGCRRVGRPEDGAEEIRAHPFFNTADTVTGRE 480
>Hs4885349 [T] KOG0986 G protein-coupled receptor kinase
Length = 590
Score = 101 bits (251), Expect = 5e-21
Identities = 54/148 (36%), Positives = 86/148 (57%), Gaps = 2/148 (1%)
Query: 347 FNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDSPW 406
F +V+GKG FGEV Q + TGK+YA K L K + + + E+ +L +S +
Sbjct: 186 FRQYRVLGKGGFGEVCACQVRATGKMYACKRLEKKRIKKRKGESMALNEKQILEKVNSQF 245
Query: 407 VVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRW--QIFTEDVTRFYMAECILAIEVIHKL 464
VV+L Y+++ L L++ + GGDL + F E+ FY AE + +E +H+
Sbjct: 246 VVNLAYAYETKDALCLVLTIMNGGDLKFHIYNMGNPGFEEERALFYAAEILCGLEDLHRE 305
Query: 465 GFIHRDIKPDNILIDIRGHIKLSDFGLS 492
++RD+KP+NIL+D GHI++SD GL+
Sbjct: 306 NTVYRDLKPENILLDDYGHIRISDLGLA 333
Score = 67.4 bits (163), Expect = 8e-11
Identities = 41/126 (32%), Positives = 67/126 (52%), Gaps = 12/126 (9%)
Query: 575 VGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETP----QETYRKIMNFE 630
VGT Y+APE+ Q YG D+W LG ++YE + G PF +E R+++ E
Sbjct: 346 VGTVGYMAPEVLNNQRYGLSPDYWGLGCLIYEMIEGQSPFRGRKEKVKREEVDRRVLETE 405
Query: 631 QTLQFPDDIHISYEAEDLIRRLLT-HSENRLG-RHGGADEIKAHPFFSGVDWNTIR--QV 686
+ S EA+ + + LLT ++ RLG + GA E+K HPFF +++ + +
Sbjct: 406 EVYSH----KFSEEAKSICKMLLTKDAKQRLGCQEEGAAEVKRHPFFRNMNFKRLEAGML 461
Query: 687 EAPYIP 692
+ P++P
Sbjct: 462 DPPFVP 467
>7299322 [R] KOG0611 Predicted serine/threonine protein kinase
Length = 434
Score = 101 bits (251), Expect = 5e-21
Identities = 49/149 (32%), Positives = 89/149 (58%)
Query: 347 FNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDSPW 406
F+ +K +G+G +G+V+L K+TG+ A+KT+ K ++ + L ++ E +++ P
Sbjct: 82 FDIIKKLGQGTYGKVQLGINKETGQEVAIKTIKKCKIEAEADLVRIRREVQIMSSVHHPN 141
Query: 407 VVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKLGF 466
++ +Y F++ + + L+MEF GG+L L ++ TE+ R + A+ HK
Sbjct: 142 IIHIYEVFENREKMVLVMEFAAGGELYDYLSERKVLTEEEARRIFRQVATAVYYCHKHKI 201
Query: 467 IHRDIKPDNILIDIRGHIKLSDFGLSTGF 495
HRD+K +NIL+D +G+ K++DFGLS F
Sbjct: 202 CHRDLKLENILLDEKGNAKIADFGLSNVF 230
Score = 35.0 bits (79), Expect = 0.43
Identities = 18/40 (45%), Positives = 23/40 (57%), Gaps = 1/40 (2%)
Query: 576 GTPDYIAPEIFLYQGY-GQECDWWSLGAIMYECLIGWPPF 614
G+P Y +PEI Y G E D WSLG ++Y + G PF
Sbjct: 241 GSPLYASPEIVEGTPYQGPEVDCWSLGVLLYTLVYGSMPF 280
>Hs4885347 [T] KOG0986 G protein-coupled receptor kinase
Length = 500
Score = 100 bits (250), Expect = 6e-21
Identities = 57/149 (38%), Positives = 84/149 (56%), Gaps = 2/149 (1%)
Query: 347 FNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDSPW 406
F +V+GKG FGEV Q + TGK+YA K L K + + A E+ +L S +
Sbjct: 155 FRHYRVLGKGGFGEVCACQVRATGKMYACKKLQKKRIKKRKGEAMALNEKRILEKVQSRF 214
Query: 407 VVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRW--QIFTEDVTRFYMAECILAIEVIHKL 464
VVSL Y+++ L L++ + GGDL + F E FY AE +E + +
Sbjct: 215 VVSLAYAYETKDALCLVLTIMNGGDLKFHIYNLGNPGFDEQRAVFYAAELCCGLEDLQRE 274
Query: 465 GFIHRDIKPDNILIDIRGHIKLSDFGLST 493
++RD+KP+NIL+D RGHI++SD GL+T
Sbjct: 275 RIVYRDLKPENILLDDRGHIRISDLGLAT 303
Score = 59.7 bits (143), Expect = 2e-08
Identities = 41/128 (32%), Positives = 65/128 (50%), Gaps = 16/128 (12%)
Query: 575 VGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQ 634
VGT Y+APE+ + Y DWW LG ++YE + G PF + Y++ + +E+ Q
Sbjct: 315 VGTVGYMAPEVVNNEKYTFSPDWWGLGCLIYEMIQGHSPF------KKYKEKVKWEEVDQ 368
Query: 635 -FPDDIH-----ISYEAEDLIRRLLT-HSENRLGRHG-GADEIKAHPFFSGVDWNTI--R 684
+D S +A+ + R LLT + RLG G GA +K HP F +++ +
Sbjct: 369 RIKNDTEEYSEKFSEDAKSICRMLLTKNPSKRLGCRGEGAAGVKQHPVFKDINFRRLEAN 428
Query: 685 QVEAPYIP 692
+E P+ P
Sbjct: 429 MLEPPFCP 436
>Hs4504101 [T] KOG0986 G protein-coupled receptor kinase
Length = 576
Score = 100 bits (250), Expect = 6e-21
Identities = 56/148 (37%), Positives = 84/148 (55%), Gaps = 2/148 (1%)
Query: 347 FNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDSPW 406
F +V+GKG FGEV Q + TGK+YA K L K + + A E+ +L +S +
Sbjct: 186 FRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALNEKQILEKVNSRF 245
Query: 407 VVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRW--QIFTEDVTRFYMAECILAIEVIHKL 464
VVSL Y+++ L L++ + GGDL + F E FY AE +E +H+
Sbjct: 246 VVSLAYAYETKDALCLVLTLMNGGDLKFHIYHMGQAGFPEARAVFYAAEICCGLEDLHRE 305
Query: 465 GFIHRDIKPDNILIDIRGHIKLSDFGLS 492
++RD+KP+NIL+D GHI++SD GL+
Sbjct: 306 RIVYRDLKPENILLDDHGHIRISDLGLA 333
Score = 58.5 bits (140), Expect = 4e-08
Identities = 37/122 (30%), Positives = 58/122 (47%), Gaps = 4/122 (3%)
Query: 575 VGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQ 634
VGT Y+APE+ + Y DWW+LG ++YE + G PF + ++ + +
Sbjct: 346 VGTVGYMAPEVVKNERYTFSPDWWALGCLLYEMIAGQSPFQQRKKKIKREEVERLVKEVP 405
Query: 635 FPDDIHISYEAEDLIRRLLTHS-ENRLG-RHGGADEIKAHPFFSGVDWNTI--RQVEAPY 690
S +A L +LL RLG R G A E+K HP F +++ + +E P+
Sbjct: 406 EEYSERFSPQARSLCSQLLCKDPAERLGCRGGSAREVKEHPLFKKLNFKRLGAGMLEPPF 465
Query: 691 IP 692
P
Sbjct: 466 KP 467
>ECU07g0520 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 322
Score = 100 bits (250), Expect = 6e-21
Identities = 62/149 (41%), Positives = 86/149 (57%), Gaps = 2/149 (1%)
Query: 346 DFNSVKVIGKGAFGEVRLVQKKDTG-KIYAMKTLLKSEMYNKDQLAHVKAERDVLAGS-D 403
DF VKV+G GAFG+V LV+ K + ++AMK L E+ + ++ E +L
Sbjct: 6 DFEFVKVVGVGAFGKVHLVRLKSSPTSVFAMKMLDFGEILRQRLADQLENEISILKRIYG 65
Query: 404 SPWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHK 463
P+V LY + + LIME++ GG+L L + F E + RFY AE I A+ IH
Sbjct: 66 CPFVAKLYSTDFHGGKVGLIMEYVGGGELFYWLKKCGRFDEQMARFYAAEIISALRFIHG 125
Query: 464 LGFIHRDIKPDNILIDIRGHIKLSDFGLS 492
G ++RD+KP+NILI GHIKL DFG S
Sbjct: 126 RGILYRDLKPENILITSTGHIKLIDFGFS 154
Score = 85.9 bits (211), Expect = 2e-16
Identities = 54/147 (36%), Positives = 80/147 (53%), Gaps = 11/147 (7%)
Query: 572 YSTVGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQ 631
Y GTP+Y++PE + G+ D+W LG ++YE L G PPF + Y KI+ E
Sbjct: 162 YMISGTPEYMSPEKLRSEDDGRASDYWGLGVMIYEMLCGDPPFYDSSADAIYHKIL--ES 219
Query: 632 TLQFPDDIHISYEAEDLIRRLLTHSENRLGRHG--GADEIKAHPFFSGVDWNTI--RQVE 687
+ FP ++S A LI LL +NR R G G EI HPFF G+DW+ + R++E
Sbjct: 220 NVVFPH--YVSPVARCLITGLL--DKNRATRLGTKGICEIMGHPFFKGIDWHEVESRRIE 275
Query: 688 APYIPKLSSVTDTRFFPTDELENVPDS 714
P+IP ++V + + EL+ D+
Sbjct: 276 PPFIPNPNTVLSS-LASSGELKGTDDA 301
>Hs4506529 [T] KOG0986 G protein-coupled receptor kinase
Length = 563
Score = 100 bits (248), Expect = 1e-20
Identities = 57/157 (36%), Positives = 86/157 (54%), Gaps = 14/157 (8%)
Query: 345 DDFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDS 404
D F +V+GKG FGEV Q K TGK+YA K L K + + E+ +L S
Sbjct: 188 DWFLDFRVLGKGGFGEVSACQMKATGKLYACKKLNKKRLKKRKGYQGAMVEKKILMKVHS 247
Query: 405 PWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQI---------FTEDVTRFYMAECI 455
++VSL Y+F+ L L+M + GGD IR+ I F E FY A+ I
Sbjct: 248 RFIVSLAYAFETKADLCLVMTIMNGGD-----IRYHIYNVNEENPGFPEPRALFYTAQII 302
Query: 456 LAIEVIHKLGFIHRDIKPDNILIDIRGHIKLSDFGLS 492
+E +H+ ++RD+KP+N+L+D G++++SD GL+
Sbjct: 303 CGLEHLHQRRIVYRDLKPENVLLDNDGNVRISDLGLA 339
Score = 57.0 bits (136), Expect = 1e-07
Identities = 39/131 (29%), Positives = 68/131 (51%), Gaps = 14/131 (10%)
Query: 576 GTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMN--FEQTL 633
GTP ++APE+ + Y D+++LG +YE + PF + + +++ + + +
Sbjct: 354 GTPGFMAPELLQGEEYDFSVDYFALGVTLYEMIAARGPFRARGEKVENKELKHRIISEPV 413
Query: 634 QFPDDIHISYEAEDLIRRLLTHS-ENRLG-RHGGADEIKAHPFFSGVDWNTIRQVEA--- 688
++PD S ++D LL E RLG R D+++AHP F ++W RQ+EA
Sbjct: 414 KYPD--KFSQASKDFCEALLEKDPEKRLGFRDETCDKLRAHPLFKDLNW---RQLEAGML 468
Query: 689 --PYIPKLSSV 697
P+IP +V
Sbjct: 469 MPPFIPDSKTV 479
>Hs13569922 [R] KOG0611 Predicted serine/threonine protein kinase
Length = 628
Score = 100 bits (248), Expect = 1e-20
Identities = 42/151 (27%), Positives = 95/151 (62%), Gaps = 1/151 (0%)
Query: 347 FNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDSPW 406
+ ++ +GKG +G+V+ ++ +G++ A+K++ K ++ ++ L H++ E ++++ + P
Sbjct: 53 YEFLETLGKGTYGKVKKA-RESSGRLVAIKSIRKDKIKDEQDLMHIRREIEIMSSLNHPH 111
Query: 407 VVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKLGF 466
+++++ F++S + ++ME+ GDL + Q +E R + + + A+ H+
Sbjct: 112 IIAIHEVFENSSKIVIVMEYASRGDLYDYISERQQLSEREARHFFRQIVSAVHYCHQNRV 171
Query: 467 IHRDIKPDNILIDIRGHIKLSDFGLSTGFHK 497
+HRD+K +NIL+D G+IK++DFGLS +H+
Sbjct: 172 VHRDLKLENILLDANGNIKIADFGLSNLYHQ 202
Score = 35.0 bits (79), Expect = 0.43
Identities = 20/54 (37%), Positives = 29/54 (53%), Gaps = 1/54 (1%)
Query: 576 GTPDYIAPEIFLYQGY-GQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMN 628
G+P Y +PEI + Y G E D WSLG ++Y + G PF + ++I N
Sbjct: 211 GSPLYASPEIVNGKPYTGPEVDSWSLGVLLYILVHGTMPFDGHDHKILVKQISN 264
>At4g24400 [T] KOG0583 Serine/threonine protein kinase
Length = 445
Score = 100 bits (248), Expect = 1e-20
Identities = 48/142 (33%), Positives = 82/142 (56%)
Query: 351 KVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDSPWVVSL 410
+ IG+G F +V+ Q +TG+ AMK + +S + + + +K E ++ P VV L
Sbjct: 13 RTIGEGTFAKVKFAQNTETGESVAMKIVDRSTIIKRKMVDQIKREISIMKLVRHPCVVRL 72
Query: 411 YYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKLGFIHRD 470
Y +Y+I+E++ GG+L ++R +E R Y + I ++ H G HRD
Sbjct: 73 YEVLASRTKIYIILEYITGGELFDKIVRNGRLSESEARKYFHQLIDGVDYCHSKGVYHRD 132
Query: 471 IKPDNILIDIRGHIKLSDFGLS 492
+KP+N+L+D +G++K+SDFGLS
Sbjct: 133 LKPENLLLDSQGNLKISDFGLS 154
Score = 51.2 bits (121), Expect = 6e-06
Identities = 29/82 (35%), Positives = 43/82 (52%), Gaps = 5/82 (6%)
Query: 573 STVGTPDYIAPEIFLYQGY-GQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQ 631
+T GTP+Y+APE+ ++GY G D WS G I+Y + G+ PF Y KI
Sbjct: 166 TTCGTPNYVAPEVLSHKGYNGAVADIWSCGVILYVLMAGYLPFDEMDLPTLYSKI----D 221
Query: 632 TLQFPDDIHISYEAEDLIRRLL 653
+F + + A+ LI R+L
Sbjct: 222 KAEFSCPSYFALGAKSLINRIL 243
>7297611 [T] KOG0614 cGMP-dependent protein kinase
Length = 1003
Score = 99.0 bits (245), Expect = 2e-20
Identities = 50/148 (33%), Positives = 87/148 (58%), Gaps = 3/148 (2%)
Query: 346 DFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGS-DS 404
+ + +G GAFG V LV + A+K + K E+ +DQ+ HV E++V+ S
Sbjct: 693 ELKKIATLGCGAFGRVDLVAYNQ--QALALKIIKKIEVVKQDQIEHVYNEKNVMIKCRQS 750
Query: 405 PWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKL 464
P++V LY ++++ +Y+Y +ME GGD+ T++ + Q F E +F + A + +H
Sbjct: 751 PFIVQLYRTYRNDKYVYFLMEACMGGDVWTVMSKRQYFDEKTAKFIAGCVVEAFDYLHSH 810
Query: 465 GFIHRDIKPDNILIDIRGHIKLSDFGLS 492
FI+RD+KP+N+++ G+ KL DFG +
Sbjct: 811 HFIYRDLKPENLMLGTDGYCKLVDFGFA 838
Score = 82.8 bits (203), Expect = 2e-15
Identities = 48/144 (33%), Positives = 78/144 (53%), Gaps = 6/144 (4%)
Query: 576 GTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQF 635
GTP+Y+APEI L +G+ + D+W+LG ++YE L+G PF + Y++I++ +
Sbjct: 852 GTPEYVAPEIILDRGHDRAVDYWALGILVYELLVGKTPFRGVNQIKIYQQILSGIDVIHM 911
Query: 636 PDDIHISYEAEDLIRRLLTH-SENRLG-RHGGADEIKAHPFFSGVDWN--TIRQVEAPYI 691
P I A+ L+R L RLG + G +IK H +F +DW ++Q+ +P
Sbjct: 912 PS--RIPKSAQHLVRHLCKQLPAERLGYQRKGIADIKRHSWFESLDWQRLKLKQLPSPIK 969
Query: 692 PKLSSVTDTRFFPTDELENVPDSP 715
L S TD ++F +EN + P
Sbjct: 970 RPLKSWTDLQYFGPSGVENDYEPP 993
>Hs4507275 [D] KOG0580 Serine/threonine protein kinase
Length = 403
Score = 98.6 bits (244), Expect = 3e-20
Identities = 61/186 (32%), Positives = 94/186 (49%), Gaps = 18/186 (9%)
Query: 307 ESELASQDWSEERKNRQLASLGKKESQFXXXXXXXXXXDDFNSVKVIGKGAFGEVRLVQK 366
E ELAS+ +EE K RQ A +DF + +GKG FG V L ++
Sbjct: 111 EEELASKQKNEESKKRQWA------------------LEDFEIGRPLGKGKFGNVYLARE 152
Query: 367 KDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDSPWVVSLYYSFQDSQYLYLIMEF 426
K + I A+K L K+++ ++ E ++ + P ++ LY F D+ +YLI+E+
Sbjct: 153 KQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEY 212
Query: 427 LPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKLGFIHRDIKPDNILIDIRGHIKL 486
P G + L + F E T Y+ E A+ H IHRDIKP+N+L+ G +K+
Sbjct: 213 APLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKI 272
Query: 487 SDFGLS 492
+DFG S
Sbjct: 273 ADFGWS 278
Score = 68.2 bits (165), Expect = 5e-11
Identities = 37/84 (44%), Positives = 53/84 (63%), Gaps = 4/84 (4%)
Query: 576 GTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQF 635
GT DY+ PE+ + + ++ D WSLG + YE L+G PPF + T QETY++I E T F
Sbjct: 291 GTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFT--F 348
Query: 636 PDDIHISYEAEDLIRRLLTHSENR 659
PD ++ A DLI RLL H+ ++
Sbjct: 349 PD--FVTEGARDLISRLLKHNPSQ 370
>SPCC162.10 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 338
Score = 98.2 bits (243), Expect = 4e-20
Identities = 52/156 (33%), Positives = 91/156 (58%), Gaps = 2/156 (1%)
Query: 347 FNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDSPW 406
F VIGKG++ V +V+ + T + +A+K + K + +++ ++ ++ E +L + P
Sbjct: 30 FKIRNVIGKGSWSTVFVVKHRQTKQRFALKCINKKK-HDEHKIKKLRNEVLLLQSLNHPL 88
Query: 407 VVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKLGF 466
+ Y F+D +YL+ + + GGDL + + + F E V R +M E + A+ IH G
Sbjct: 89 LCKFYSEFEDETKIYLVTDLMLGGDLRYHISQRK-FNESVIRIWMVELVSALIYIHSKGV 147
Query: 467 IHRDIKPDNILIDIRGHIKLSDFGLSTGFHKTHDSS 502
+HRD+KPDNIL+D +GH KL+DF ++ H + S
Sbjct: 148 LHRDVKPDNILLDEKGHCKLADFNVAAKVHTSSSPS 183
Score = 54.7 bits (130), Expect = 5e-07
Identities = 36/130 (27%), Positives = 56/130 (42%), Gaps = 14/130 (10%)
Query: 566 SRRLMAYSTVGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSE-------- 617
S+ M VGTP Y+APE ++ +E DWWSLG YECL PF +
Sbjct: 183 SKSNMTVGRVGTPVYMAPETLIHAVSYKESDWWSLGITFYECLFQVRPFPNHLLINWIRA 242
Query: 618 TPQETYRKIMNFEQTLQFPDDIHISYEAEDLIRRLLTHSE----NRLGRHGGADEIKAHP 673
+ +E L D ++ ++D ++ E RLG + +++ HP
Sbjct: 243 SEEEKASSADRLSSALHISRDKKLTTISKDARSAVMAFLEMDIKKRLGH--SSKKLQTHP 300
Query: 674 FFSGVDWNTI 683
FF + T+
Sbjct: 301 FFCSISLETV 310
>Hs4507273 [D] KOG0580 Serine/threonine protein kinase
Length = 275
Score = 98.2 bits (243), Expect = 4e-20
Identities = 56/149 (37%), Positives = 87/149 (57%), Gaps = 2/149 (1%)
Query: 345 DDFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAH-VKAERDVLAGSD 403
DDF + +GKG FG V L + K++ I A+K L KS++ K+ L H ++ E ++ A
Sbjct: 7 DDFEIGRPLGKGKFGNVYLARLKESHFIVALKVLFKSQI-EKEGLEHQLRREIEIQAHLQ 65
Query: 404 SPWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHK 463
P ++ LY F D++ +YLI+E+ P G+L L + + E T + E A+ H
Sbjct: 66 HPNILRLYNYFHDARRVYLILEYAPRGELYKELQKSEKLDEQRTATIIEEVADALTYCHD 125
Query: 464 LGFIHRDIKPDNILIDIRGHIKLSDFGLS 492
IHRDIKP+N+L+ RG +K++DFG S
Sbjct: 126 KKVIHRDIKPENLLLGFRGEVKIADFGWS 154
Score = 63.2 bits (152), Expect = 1e-09
Identities = 32/80 (40%), Positives = 50/80 (62%), Gaps = 4/80 (5%)
Query: 576 GTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQF 635
GT DY+ PE+ + Y ++ D W +G + YE L+G+PPF S + ETYR+I+ + ++F
Sbjct: 167 GTLDYLPPEMIEGRTYDEKVDLWCIGVLCYELLVGYPPFESASHSETYRRILKVD--VRF 224
Query: 636 PDDIHISYEAEDLIRRLLTH 655
P + + A DLI RLL +
Sbjct: 225 P--LSMPLGARDLISRLLRY 242
>CE20142 [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 320
Score = 98.2 bits (243), Expect = 4e-20
Identities = 57/158 (36%), Positives = 90/158 (56%), Gaps = 11/158 (6%)
Query: 346 DFNSVKVIGKGAFGEVRLVQKK----DTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLA- 400
D++ K +G+G+F V L ++K D A+K LK + + ++ E++ LA
Sbjct: 25 DYSVEKEVGEGSFSTVYLARRKEPKNDENPEVALKICLKRLILKNKMVPYIHREKEALAL 84
Query: 401 ----GSDSPWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRW--QIFTEDVTRFYMAEC 454
+ P +V+LY +FQDS+ LY ++E+ GDL T++ + F +R+Y A
Sbjct: 85 ISREENAHPGIVTLYATFQDSESLYFVLEYAKYGDLCTLMQKQPDSKFNVADSRYYAANL 144
Query: 455 ILAIEVIHKLGFIHRDIKPDNILIDIRGHIKLSDFGLS 492
+ A+E IHKLG IHRD+K DN+L+ G I L+DFG S
Sbjct: 145 LSALEHIHKLGIIHRDVKADNLLVKSDGRIMLTDFGSS 182
Score = 54.3 bits (129), Expect = 7e-07
Identities = 38/122 (31%), Positives = 57/122 (46%), Gaps = 12/122 (9%)
Query: 573 STVGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQT 632
S VGT ++ PE+ D W+ +Y L G PF + +R+I + T
Sbjct: 207 SFVGTAFFVTPELLTGSEMSPSSDLWAFSVTLYLFLTGIYPFNDMSEYLVFRRIQDILYT 266
Query: 633 L--QFPDDIHISYEAEDLIRRLLT-HSENRLGRHGGADEIKAHPFFSGVDWNTIRQVEAP 689
FPD+ A++LI RLL ++RL + EIK H FF +D+ + Q+E P
Sbjct: 267 FSEDFPDE-----NAKNLIERLLVKEQKSRL----TSQEIKEHKFFESIDFEHLEQLEPP 317
Query: 690 YI 691
I
Sbjct: 318 RI 319
>Hs4759178 [D] KOG0580 Serine/threonine protein kinase
Length = 344
Score = 97.8 bits (242), Expect = 5e-20
Identities = 54/148 (36%), Positives = 84/148 (56%)
Query: 345 DDFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDS 404
DDF + +GKG FG V L ++K + I A+K L KS++ + ++ E ++ A
Sbjct: 75 DDFEIGRPLGKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQAHLHH 134
Query: 405 PWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKL 464
P ++ LY F D + +YLI+E+ P G+L L + F E T M E A+ H
Sbjct: 135 PNILRLYNYFYDRRRIYLILEYAPRGELYKELQKSCTFDEQRTATIMEELADALMYCHGK 194
Query: 465 GFIHRDIKPDNILIDIRGHIKLSDFGLS 492
IHRDIKP+N+L+ ++G +K++DFG S
Sbjct: 195 KVIHRDIKPENLLLGLKGELKIADFGWS 222
Score = 62.8 bits (151), Expect = 2e-09
Identities = 35/99 (35%), Positives = 57/99 (57%), Gaps = 7/99 (7%)
Query: 576 GTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQF 635
GT DY+ PE+ + + ++ D W +G + YE L+G PPF S + ETYR+I+ + L+F
Sbjct: 235 GTLDYLPPEMIEGRMHNEKVDLWCIGVLCYELLVGNPPFESASHNETYRRIVKVD--LKF 292
Query: 636 PDDIHISYEAEDLIRRLLTHSENRLGRHGGADEIKAHPF 674
P + A+DLI +LL H+ + ++ AHP+
Sbjct: 293 PASVPTG--AQDLISKLLRHNPS---ERLPLAQVSAHPW 326
>CE24761 [D] KOG0580 Serine/threonine protein kinase
Length = 305
Score = 97.8 bits (242), Expect = 5e-20
Identities = 54/167 (32%), Positives = 90/167 (53%)
Query: 326 SLGKKESQFXXXXXXXXXXDDFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYN 385
+L +KE+ +DF + +GKG FG V L + K A+K L KS++ +
Sbjct: 9 NLPEKETVNTPQKGGKFTINDFEIGRPLGKGKFGSVYLARTKTGHFHVAIKVLFKSQLIS 68
Query: 386 KDQLAHVKAERDVLAGSDSPWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTED 445
++ E ++ + + P ++ LY F D++ +YL++E+ PGG++ L + F+E
Sbjct: 69 GGVEHQLEREIEIQSHLNHPNIIKLYTYFWDAKKIYLVLEYAPGGEMYKQLTVSKRFSEP 128
Query: 446 VTRFYMAECILAIEVIHKLGFIHRDIKPDNILIDIRGHIKLSDFGLS 492
YM E A+ H+ IHRDIKP+N+LI +G +K+ DFG S
Sbjct: 129 TAAKYMYEIADALSYCHRKNVIHRDIKPENLLIGSQGELKIGDFGWS 175
Score = 52.4 bits (124), Expect = 3e-06
Identities = 38/122 (31%), Positives = 56/122 (45%), Gaps = 7/122 (5%)
Query: 576 GTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQF 635
GT DY+ PE+ + D W++G + YE L+G PPF E +TY I T +
Sbjct: 188 GTMDYLPPEMVNGADHSDAVDLWAIGVLCYEFLVGKPPFEHEDQSKTYAAIKAARFT--Y 245
Query: 636 PDDIHISYEAEDLIRRLLTHSENRLGRHGGADEIKAHPFFSGVDWNTIRQVEAPYIPKLS 695
PD + A DLI RLL +++K H + G+ IR + I K +
Sbjct: 246 PDS--VKKGARDLIGRLLVVDPK---ARCTLEQVKEHYWIQGMMEAKIRAEKQQKIEKEA 300
Query: 696 SV 697
S+
Sbjct: 301 SL 302
>YPL209c [D] KOG0580 Serine/threonine protein kinase
Length = 367
Score = 97.4 bits (241), Expect = 7e-20
Identities = 53/148 (35%), Positives = 82/148 (54%)
Query: 345 DDFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDS 404
DDF K +GKG FG+V V+ + TG I A+K + K E+ + + E ++ +
Sbjct: 102 DDFELGKKLGKGKFGKVYCVRHRSTGYICALKVMEKEEIIKYNLQKQFRREVEIQTSLNH 161
Query: 405 PWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKL 464
P + Y F D + +YL+ME+L G++ +L F + + Y+ + A++ +HK
Sbjct: 162 PNLTKSYGYFHDEKRVYLLMEYLVNGEMYKLLRLHGPFNDILASDYIYQIANALDYMHKK 221
Query: 465 GFIHRDIKPDNILIDIRGHIKLSDFGLS 492
IHRDIKP+NILI IKL+DFG S
Sbjct: 222 NIIHRDIKPENILIGFNNVIKLTDFGWS 249
Score = 60.1 bits (144), Expect = 1e-08
Identities = 35/99 (35%), Positives = 55/99 (55%), Gaps = 7/99 (7%)
Query: 576 GTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQF 635
GT DY++PE+ + Y D W+LG + +E L G PPF E TY++I + ++
Sbjct: 263 GTIDYLSPEMVESREYDHTIDAWALGVLAFELLTGAPPFEEEMKDTTYKRIAALD--IKM 320
Query: 636 PDDIHISYEAEDLIRRLLTHSENRLGRHGGADEIKAHPF 674
P +IS +A+DLI +LL + R G ++K HP+
Sbjct: 321 PS--NISQDAQDLILKLLKYDPKDRMRLG---DVKMHPW 354
>At5g45810 [T] KOG0583 Serine/threonine protein kinase
Length = 483
Score = 97.1 bits (240), Expect = 9e-20
Identities = 51/171 (29%), Positives = 92/171 (52%), Gaps = 4/171 (2%)
Query: 322 RQLASLGKKESQFXXXXXXXXXXDDFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKS 381
R++ S+ KK+ Q + +++G G F +V L + +G+ A+K + K
Sbjct: 6 RKVKSIKKKQDQ---SNHQALILGKYEMGRLLGHGTFAKVYLARNAQSGESVAIKVIDKE 62
Query: 382 EMYNKDQLAHVKAERDVLAGSDSPWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQI 441
++ +AH+K E +L P +V L+ +Y +ME++ GG+L + + ++
Sbjct: 63 KVLKSGLIAHIKREISILRRVRHPNIVQLFEVMATKSKIYFVMEYVKGGELFNKVAKGRL 122
Query: 442 FTEDVTRFYMAECILAIEVIHKLGFIHRDIKPDNILIDIRGHIKLSDFGLS 492
E++ R Y + I A+ H G HRD+KP+N+L+D G++K+SDFGLS
Sbjct: 123 -KEEMARKYFQQLISAVSFCHFRGVYHRDLKPENLLLDENGNLKVSDFGLS 172
Score = 48.9 bits (115), Expect = 3e-05
Identities = 32/87 (36%), Positives = 44/87 (49%), Gaps = 8/87 (9%)
Query: 576 GTPDYIAPEIFLYQGY-GQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIM--NFEQT 632
GTP Y+APE+ +GY G + D WS G I++ + G+ PF Y+KI +F
Sbjct: 189 GTPAYVAPEVLARKGYDGAKVDIWSCGVILFVLMAGFLPFHDRNVMAMYKKIYRGDFRCP 248
Query: 633 LQFPDDIHISYEAEDLIRRLLTHSENR 659
FP +I+ LIR L T E R
Sbjct: 249 RWFPVEIN-----RLLIRMLETKPERR 270
>7293512 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 483
Score = 97.1 bits (240), Expect = 9e-20
Identities = 51/143 (35%), Positives = 86/143 (59%), Gaps = 5/143 (3%)
Query: 352 VIGKGAFGEV-RLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVL-AGSDSPWVVS 409
++ KGAFG V ++ K D + YA+K L KS++ + + +K E D+ P++V
Sbjct: 164 LVAKGAFGVVFKVSSKSDISQCYALKVLKKSKLIEDNSVRQIKDEADIQKVCGHHPFIVK 223
Query: 410 LYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKLGFIHR 469
+Q+ L+++ E++P G+L + + + I D+ R Y+ E LA++ +H G I+R
Sbjct: 224 QIDLWQNRHNLHILSEYVPNGELFSKITHFSI---DLVRLYIGEIALALDFLHNAGIIYR 280
Query: 470 DIKPDNILIDIRGHIKLSDFGLS 492
D KP+NIL+ + HIKL+DFGLS
Sbjct: 281 DAKPENILLTEQFHIKLTDFGLS 303
Score = 43.9 bits (102), Expect = 0.001
Identities = 38/137 (27%), Positives = 61/137 (43%), Gaps = 30/137 (21%)
Query: 543 NTMLVDAIHLTMTNRQQMQTWRK---SRRLMAYSTVGTPDYIAPEIFLYQGYGQECDWWS 599
N +L + H+ +T+ + W K + R M GT Y+APEI + YG DWW+
Sbjct: 286 NILLTEQFHIKLTDFG-LSKWLKLGANTRTMC----GTFKYMAPEILCGEPYGHAVDWWA 340
Query: 600 LGAIMYECLIGWPPFC---------SETPQETYRKIMNFEQ---TLQ---------FPDD 638
LG I + L P S P++ + Q LQ P++
Sbjct: 341 LGVIACQMLTQKSPNIKRHLLRRRESVEPEDGLSNAPSIAQINGCLQDSDGDSEDFLPEE 400
Query: 639 I-HISYEAEDLIRRLLT 654
+ H+++E D++R+LLT
Sbjct: 401 VQHLTHEGRDVLRKLLT 417
>At1g29230 [T] KOG0583 Serine/threonine protein kinase
Length = 520
Score = 96.7 bits (239), Expect = 1e-19
Identities = 47/142 (33%), Positives = 82/142 (57%), Gaps = 1/142 (0%)
Query: 351 KVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDSPWVVSL 410
K++G G F +V L Q +G A+K + K ++ +AH+K E +L P++V L
Sbjct: 78 KLLGHGTFAKVYLAQNIKSGDKVAIKVIDKEKIMKSGLVAHIKREISILRRVRHPYIVHL 137
Query: 411 YYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKLGFIHRD 470
+ +Y +ME++ GG+L + + ++ E+ R Y + I ++ H G HRD
Sbjct: 138 FEVMATKSKIYFVMEYVGGGELFNTVAKGRL-PEETARRYFQQLISSVSFCHGRGVYHRD 196
Query: 471 IKPDNILIDIRGHIKLSDFGLS 492
+KP+N+L+D +G++K+SDFGLS
Sbjct: 197 LKPENLLLDNKGNLKVSDFGLS 218
Score = 44.3 bits (103), Expect = 7e-04
Identities = 22/62 (35%), Positives = 33/62 (52%), Gaps = 1/62 (1%)
Query: 570 MAYSTVGTPDYIAPEIFLYQGY-GQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMN 628
+ ++ GTP YIAPE+ +GY + D WS G I++ + G PF + Y+KI
Sbjct: 229 LCHTFCGTPAYIAPEVLTRKGYDAAKADVWSCGVILFVLMAGHIPFYDKNIMVMYKKIYK 288
Query: 629 FE 630
E
Sbjct: 289 GE 290
>At4g18700 [T] KOG0583 Serine/threonine protein kinase
Length = 489
Score = 95.1 bits (235), Expect = 4e-19
Identities = 48/142 (33%), Positives = 81/142 (56%), Gaps = 1/142 (0%)
Query: 351 KVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDSPWVVSL 410
K++G G F +V L + T + A+K + K ++ +AH+K E +L P +V L
Sbjct: 30 KLLGHGTFAKVYLARNVKTNESVAIKVIDKEKVLKGGLIAHIKREISILRRVRHPNIVQL 89
Query: 411 YYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKLGFIHRD 470
+ +Y +ME++ GG+L + + ++ E+V R Y + I A+ H G HRD
Sbjct: 90 FEVMATKAKIYFVMEYVRGGELFNKVAKGRL-KEEVARKYFQQLISAVTFCHARGVYHRD 148
Query: 471 IKPDNILIDIRGHIKLSDFGLS 492
+KP+N+L+D G++K+SDFGLS
Sbjct: 149 LKPENLLLDENGNLKVSDFGLS 170
Score = 44.7 bits (104), Expect = 5e-04
Identities = 30/86 (34%), Positives = 42/86 (47%), Gaps = 6/86 (6%)
Query: 576 GTPDYIAPEIFLYQGY-GQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQ 634
GTP Y+APE+ +GY + D WS G I++ + G+ PF Y+KI E
Sbjct: 187 GTPAYVAPEVLARKGYDAAKVDIWSCGVILFVLMAGYLPFHDRNVMAMYKKIYRGE---- 242
Query: 635 FPDDIHISYEAEDLIRRLL-THSENR 659
F S E L+ +LL T+ E R
Sbjct: 243 FRCPRWFSTELTRLLSKLLETNPEKR 268
>YPL153c [D] KOG0615 Serine/threonine protein kinase Chk2 and related
proteins
Length = 821
Score = 94.7 bits (234), Expect = 5e-19
Identities = 55/150 (36%), Positives = 89/150 (58%), Gaps = 5/150 (3%)
Query: 346 DFNSV-KVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDS 404
DF+ + +V+G+GAF V+ ++ TGK +A+K + K ++ + V E +VL +
Sbjct: 196 DFSIIDEVVGQGAFATVKKAIERTTGKTFAVKIISKRKVIGN--MDGVTRELEVLQKLNH 253
Query: 405 PWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKL 464
P +V L ++D++ Y++MEF+ GGDLM + ED R + + AI+ IH +
Sbjct: 254 PRIVRLKGFYEDTESYYMVMEFVSGGDLMDFVAAHGAVGEDAGREISRQILTAIKYIHSM 313
Query: 465 GFIHRDIKPDNILI--DIRGHIKLSDFGLS 492
G HRD+KPDNILI D +K++DFGL+
Sbjct: 314 GISHRDLKPDNILIEQDDPVLVKITDFGLA 343
Score = 40.8 bits (94), Expect = 0.008
Identities = 29/96 (30%), Positives = 38/96 (39%), Gaps = 13/96 (13%)
Query: 576 GTPDYIAPEIFLYQG-------------YGQECDWWSLGAIMYECLIGWPPFCSETPQET 622
GT Y+APE+ + Y D WS+G ++Y L G PF T +
Sbjct: 357 GTLAYVAPEVIRGKDTSVSPDEYEERNEYSSLVDMWSMGCLVYVILTGHLPFSGSTQDQL 416
Query: 623 YRKIMNFEQTLQFPDDIHISYEAEDLIRRLLTHSEN 658
Y++I D IS EA D I LL N
Sbjct: 417 YKQIGRGSYHEGPLKDFRISEEARDFIDSLLQVDPN 452
>At5g35410 [T] KOG0583 Serine/threonine protein kinase
Length = 446
Score = 94.7 bits (234), Expect = 5e-19
Identities = 46/142 (32%), Positives = 78/142 (54%)
Query: 351 KVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDSPWVVSL 410
+ IG+G F +V+ + DTG A+K + KS + + +K E ++ P +V L
Sbjct: 15 RTIGEGTFAKVKFARNTDTGDNVAIKIMAKSTILKNRMVDQIKREISIMKIVRHPNIVRL 74
Query: 411 YYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKLGFIHRD 470
Y +Y+++EF+ GG+L ++ E +R Y + + A+ H G HRD
Sbjct: 75 YEVLASPSKIYIVLEFVTGGELFDRIVHKGRLEESESRKYFQQLVDAVAHCHCKGVYHRD 134
Query: 471 IKPDNILIDIRGHIKLSDFGLS 492
+KP+N+L+D G++K+SDFGLS
Sbjct: 135 LKPENLLLDTNGNLKVSDFGLS 156
Score = 53.9 bits (128), Expect = 9e-07
Identities = 38/105 (36%), Positives = 52/105 (49%), Gaps = 10/105 (9%)
Query: 573 STVGTPDYIAPEIFLYQGY-GQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQ 631
+T GTP+Y+APE+ QGY G D WS G I++ L G+ PF YRKI
Sbjct: 168 TTCGTPNYVAPEVLSGQGYDGSAADIWSCGVILFVILAGYLPFSETDLPGLYRKI----N 223
Query: 632 TLQFPDDIHISYEAEDLIRRLL-THSENRLGRHGGADEIKAHPFF 675
+F S E + LI R+L + + R+ G IK P+F
Sbjct: 224 AAEFSCPPWFSAEVKFLIHRILDPNPKTRIQIQG----IKKDPWF 264
>At2g26980 [T] KOG0583 Serine/threonine protein kinase
Length = 441
Score = 94.0 bits (232), Expect = 8e-19
Identities = 47/150 (31%), Positives = 80/150 (53%)
Query: 351 KVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDSPWVVSL 410
+ IG+G F +V+ + +TG+ A+K L K ++ ++ E + P VV L
Sbjct: 18 RTIGEGTFAKVKFARNSETGEPVALKILDKEKVLKHKMAEQIRREIATMKLIKHPNVVQL 77
Query: 411 YYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKLGFIHRD 470
Y +++I+E++ GG+L ++ ED R Y + I A++ H G HRD
Sbjct: 78 YEVMASKTKIFIILEYVTGGELFDKIVNDGRMKEDEARRYFQQLIHAVDYCHSRGVYHRD 137
Query: 471 IKPDNILIDIRGHIKLSDFGLSTGFHKTHD 500
+KP+N+L+D G++K+SDFGLS + D
Sbjct: 138 LKPENLLLDSYGNLKISDFGLSALSQQVRD 167
Score = 51.6 bits (122), Expect = 4e-06
Identities = 30/85 (35%), Positives = 45/85 (52%), Gaps = 5/85 (5%)
Query: 570 MAYSTVGTPDYIAPEIFLYQGY-GQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMN 628
+ +++ GTP+Y+APE+ +GY G D WS G ++Y L G+ PF Y+KI +
Sbjct: 170 LLHTSCGTPNYVAPEVLNDRGYDGATADMWSCGVVLYVLLAGYLPFDDSNLMNLYKKISS 229
Query: 629 FEQTLQFPDDIHISYEAEDLIRRLL 653
E F +S A LI R+L
Sbjct: 230 GE----FNCPPWLSLGAMKLITRIL 250
>At2g30360 [T] KOG0583 Serine/threonine protein kinase
Length = 435
Score = 93.6 bits (231), Expect = 1e-18
Identities = 50/143 (34%), Positives = 82/143 (56%), Gaps = 1/143 (0%)
Query: 351 KVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAH-VKAERDVLAGSDSPWVVS 409
K++G GAF +V + + TG+ A+K L K ++ LA+ +K E ++ P +V
Sbjct: 25 KLLGCGAFAKVFHARDRRTGQSVAVKILNKKKLLTNPALANNIKREISIMRRLSHPNIVK 84
Query: 410 LYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKLGFIHR 469
L+ ++ MEF+ GG+L + + +ED++R Y + I A+ H G HR
Sbjct: 85 LHEVMATKSKIFFAMEFVKGGELFNKISKHGRLSEDLSRRYFQQLISAVGYCHARGVYHR 144
Query: 470 DIKPDNILIDIRGHIKLSDFGLS 492
D+KP+N+LID G++K+SDFGLS
Sbjct: 145 DLKPENLLIDENGNLKVSDFGLS 167
Score = 48.5 bits (114), Expect = 4e-05
Identities = 34/108 (31%), Positives = 56/108 (51%), Gaps = 10/108 (9%)
Query: 570 MAYSTVGTPDYIAPEIFLYQGY-GQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMN 628
+ ++ GTP Y+APEI +GY G + D WS G +++ + G+ PF Y+KI
Sbjct: 178 LLHTLCGTPAYVAPEILSKKGYEGAKVDVWSCGIVLFVLVAGYLPFNDPNVMNMYKKI-- 235
Query: 629 FEQTLQFPDDIHISYEAEDLIRRLL-THSENRLGRHGGADEIKAHPFF 675
++ +FP +S + + + RLL + E R+ DEI P+F
Sbjct: 236 YKGEYRFPR--WMSPDLKRFVSRLLDINPETRI----TIDEILKDPWF 277
>SPCC576.15c [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 592
Score = 93.2 bits (230), Expect = 1e-18
Identities = 48/157 (30%), Positives = 87/157 (54%), Gaps = 1/157 (0%)
Query: 346 DFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAG-SDS 404
DF +++G+G++ V + T + YA+K L K + + + +V E++ L S
Sbjct: 98 DFKFGEILGEGSYSTVLTATENSTKREYAIKVLDKRHIIKEKKEKYVNIEKEALCILSKH 157
Query: 405 PWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKL 464
P + L+Y+FQD+ LY ++ G+L+ + + F E ++Y A + +I+ +H
Sbjct: 158 PGFIKLFYTFQDAHNLYFVLSLARNGELLDYINKLGRFNEICAQYYAALIVDSIDYMHGR 217
Query: 465 GFIHRDIKPDNILIDIRGHIKLSDFGLSTGFHKTHDS 501
G IHRD+KP+NIL+D K++DFG + + +H S
Sbjct: 218 GVIHRDLKPENILLDDNMRTKITDFGSAKILNSSHGS 254
Score = 64.7 bits (156), Expect = 5e-10
Identities = 42/119 (35%), Positives = 67/119 (56%), Gaps = 10/119 (8%)
Query: 573 STVGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQT 632
S VGT Y++PE+ + G D W+ G I+++ L G PPF + T++ I++ +
Sbjct: 271 SFVGTARYVSPEVLSDKIAGTASDIWAFGCILFQMLAGKPPFVAGNEYLTFQSILHL--S 328
Query: 633 LQFPDDIHISYEAEDLIRRLLT-HSENRLGRHGGADEIKAHPFFSGVDW-NTIRQVEAP 689
+ P D IS A DLI++LL ++RL DEI HPFF+G+ + NT+ ++ P
Sbjct: 329 YEIPPD--ISDVASDLIKKLLVLDPKDRL----TVDEIHQHPFFNGIKFDNTLWELPPP 381
>Hs20547806 [R] KOG0589 Serine/threonine protein kinase
Length = 489
Score = 93.2 bits (230), Expect = 1e-18
Identities = 50/148 (33%), Positives = 86/148 (57%), Gaps = 4/148 (2%)
Query: 345 DDFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDS 404
DD+ +++IG+G+FG LVQ + + +++AMK + + ++ Q + + E +LA
Sbjct: 2 DDYMVLRMIGEGSFGRALLVQHESSNQMFAMKEIRLPKSFSNTQ--NSRKEAVLLAKMKH 59
Query: 405 PWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLI--RWQIFTEDVTRFYMAECILAIEVIH 462
P +V+ SF+ +LY++ME+ GGDLM + + ++F ED+ + + L + IH
Sbjct: 60 PNIVAFKESFEAEGHLYIVMEYCDGGDLMQKIKQQKGKLFPEDMILNWFTQMCLGVNHIH 119
Query: 463 KLGFIHRDIKPDNILIDIRGHIKLSDFG 490
K +HRDIK NI + G +KL DFG
Sbjct: 120 KKRVLHRDIKSKNIFLTQNGKVKLGDFG 147
Score = 46.6 bits (109), Expect = 1e-04
Identities = 33/108 (30%), Positives = 52/108 (47%), Gaps = 8/108 (7%)
Query: 550 IHLTMTNRQQMQTWRKSRRL-----MAYSTVGTPDYIAPEIFLYQGYGQECDWWSLGAIM 604
I LT + ++ + +R L A + VGTP Y+ PEI+ Y + D WSLG I+
Sbjct: 133 IFLTQNGKVKLGDFGSARLLSNPMAFACTYVGTPYYVPPEIWENLPYNNKSDIWSLGCIL 192
Query: 605 YECLIGWPPFCSETPQETYRKIMNFEQTLQFPDDIHISYEAEDLIRRL 652
YE PF + + + K+ Q P H SYE + L++++
Sbjct: 193 YELCTLKHPFQANSWKNLILKVC---QGCISPLPSHYSYELQFLVKQM 237
>At4g32830 [D] KOG0580 Serine/threonine protein kinase
Length = 294
Score = 93.2 bits (230), Expect = 1e-18
Identities = 50/147 (34%), Positives = 83/147 (56%)
Query: 346 DFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDSP 405
DF+ K +G+G FG V L ++K + + A+K L KS++ ++ E ++ + P
Sbjct: 30 DFDIGKPLGRGKFGHVYLAREKRSNHVVALKVLFKSQLQQSQVEHQLRREVEIQSHLRHP 89
Query: 406 WVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKLG 465
++ LY F D + +YLI+E+ G+L L + + F+E Y+A A+ H
Sbjct: 90 NILRLYGYFYDQKRVYLILEYAARGELYKDLQKCKYFSERRAATYVASLARALIYCHGKH 149
Query: 466 FIHRDIKPDNILIDIRGHIKLSDFGLS 492
IHRDIKP+N+LI +G +K++DFG S
Sbjct: 150 VIHRDIKPENLLIGAQGELKIADFGWS 176
Score = 58.9 bits (141), Expect = 3e-08
Identities = 38/100 (38%), Positives = 54/100 (54%), Gaps = 7/100 (7%)
Query: 576 GTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQF 635
GT DY+ PE+ + D WSLG + YE L G PPF + +TYR+I+ + L+F
Sbjct: 188 GTLDYLPPEMVESVEHDASVDIWSLGILCYEFLYGVPPFEAMEHSDTYRRIVQVD--LKF 245
Query: 636 PDDIHISYEAEDLIRRLLT-HSENRLGRHGGADEIKAHPF 674
P IS A+DLI ++L S RL H ++ HP+
Sbjct: 246 PPKPIISASAKDLISQMLVKESSQRLPLH----KLLEHPW 281
>At5g25110 [T] KOG0583 Serine/threonine protein kinase
Length = 460
Score = 92.8 bits (229), Expect = 2e-18
Identities = 46/142 (32%), Positives = 83/142 (58%), Gaps = 1/142 (0%)
Query: 351 KVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDSPWVVSL 410
+++GKG FG+V ++ TG+ A+K + K ++ + + +K E ++ P +V L
Sbjct: 19 RLLGKGTFGKVYYGKEITTGESVAIKIINKDQVKREGMMEQIKREISIMRLVRHPNIVEL 78
Query: 411 YYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKLGFIHRD 470
++ IME++ GG+L + +++ ++ ED R Y + I A++ H G HRD
Sbjct: 79 KEVMATKTKIFFIMEYVKGGELFSKIVKGKL-KEDSARKYFQQLISAVDFCHSRGVSHRD 137
Query: 471 IKPDNILIDIRGHIKLSDFGLS 492
+KP+N+L+D G +K+SDFGLS
Sbjct: 138 LKPENLLVDENGDLKVSDFGLS 159
Score = 57.0 bits (136), Expect = 1e-07
Identities = 34/91 (37%), Positives = 51/91 (55%), Gaps = 5/91 (5%)
Query: 570 MAYSTVGTPDYIAPEIFLYQGY-GQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMN 628
+ ++ GTP Y+APE+ +GY G + D WS G I+Y L G+ PF E + YRKI
Sbjct: 170 LLHTQCGTPAYVAPEVLRKKGYDGAKGDIWSCGIILYVLLAGFLPFQDENLMKMYRKI-- 227
Query: 629 FEQTLQFPDDIHISYEAEDLIRRLLTHSENR 659
F+ ++P S E++ LI +LL N+
Sbjct: 228 FKSEFEYPP--WFSPESKRLISKLLVVDPNK 256
>SPCC18B5.11c [D] KOG0615 Serine/threonine protein kinase Chk2 and related
proteins
Length = 460
Score = 92.4 bits (228), Expect = 2e-18
Identities = 52/156 (33%), Positives = 84/156 (53%), Gaps = 4/156 (2%)
Query: 347 FNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMY----NKDQLAHVKAERDVLAGS 402
+ ++ +G G F V+L + ++GK YA+K + K ++ K + E D+L
Sbjct: 167 YEIIRTLGSGTFAVVKLAVEVNSGKWYAIKIINKRKILLTSSEKRATEMFQREIDILKSL 226
Query: 403 DSPWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIH 462
P VV + F++ L+++ME++ GGDLM LI E + + + + + +H
Sbjct: 227 HHPGVVQCHEIFENDDELFIVMEYVEGGDLMDFLIANGSIDEQDCKPLLKQLLETLLHLH 286
Query: 463 KLGFIHRDIKPDNILIDIRGHIKLSDFGLSTGFHKT 498
K G HRDIKP+NILI H+K+SDFGL+ H T
Sbjct: 287 KQGVTHRDIKPENILITNDFHLKISDFGLAKVIHGT 322
Score = 45.4 bits (106), Expect = 3e-04
Identities = 34/107 (31%), Positives = 48/107 (44%), Gaps = 11/107 (10%)
Query: 576 GTPDYIAPEIF------LYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNF 629
GT Y+APE+ L GY + D WSLG ++Y L PF S + + I
Sbjct: 331 GTMGYLAPEVLKSKNVNLDGGYDDKVDIWSLGCVLYVMLTASIPFASSSQAKCIELISKG 390
Query: 630 EQTLQFPDDIHISYEAEDLIRRLL-THSENRLGRHGGADEIKAHPFF 675
++ + IS E DLI R+L + E R+ E HP+F
Sbjct: 391 AYPIEPLLENEISEEGIDLINRMLEINPEKRISE----SEALQHPWF 433
>At1g54960 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 585
Score = 92.4 bits (228), Expect = 2e-18
Identities = 52/147 (35%), Positives = 89/147 (60%), Gaps = 5/147 (3%)
Query: 351 KVIGKGAFGEVRLVQKKDTGKIYAMK-TLLKSEMYNKDQL-AHVKA---ERDVLAGSDSP 405
++IG+GAFG V + D+G++ A+K L+ S +K++ AH++ E +L P
Sbjct: 72 QLIGRGAFGTVYMGMNLDSGELLAVKQVLITSNCASKEKTQAHIQELEEEVKLLKNLSHP 131
Query: 406 WVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKLG 465
+V + ++ + L +++EF+PGG + ++L ++ F E V R Y + +L +E +H
Sbjct: 132 NIVRYLGTVREDETLNILLEFVPGGSISSLLEKFGAFPESVVRTYTNQLLLGLEYLHNHA 191
Query: 466 FIHRDIKPDNILIDIRGHIKLSDFGLS 492
+HRDIK NIL+D +G IKL+DFG S
Sbjct: 192 IMHRDIKGANILVDNQGCIKLADFGAS 218
Score = 39.7 bits (91), Expect = 0.017
Identities = 26/89 (29%), Positives = 41/89 (45%), Gaps = 3/89 (3%)
Query: 571 AYSTVGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFE 630
A S GTP ++APE+ L G+ D WS+G + E + G P+ + + I +
Sbjct: 230 AKSMKGTPYWMAPEVILQTGHSFSADIWSVGCTVIEMVTGKAPWSQQ--YKEIAAIFHIG 287
Query: 631 QTLQFPD-DIHISYEAEDLIRRLLTHSEN 658
T P +IS +A D + + L N
Sbjct: 288 TTKSHPPIPDNISSDANDFLLKCLQQEPN 316
>HsM7657627 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 970
Score = 92.0 bits (227), Expect = 3e-18
Identities = 51/160 (31%), Positives = 84/160 (51%), Gaps = 1/160 (0%)
Query: 345 DDFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDS 404
+DF ++GKG+F V + TG A+K + K MY + VK E +
Sbjct: 10 EDFKVGNLLGKGSFAGVYRAESIHTGLEVAIKMIDKKAMYKAGMVQRVKNEVKIHCQLKH 69
Query: 405 PWVVSLYYSFQDSQYLYLIMEFLPGGDLMTML-IRWQIFTEDVTRFYMAECILAIEVIHK 463
P ++ LY F+DS Y+YL++E G++ L R + F+E+ R +M + I + +H
Sbjct: 70 PSILELYNYFEDSNYVYLVLEMCHNGEMNRYLKNRVKPFSENEARHFMHQIITGMLYLHS 129
Query: 464 LGFIHRDIKPDNILIDIRGHIKLSDFGLSTGFHKTHDSSY 503
G +HRD+ N+L+ +IK++DFGL+T H+ Y
Sbjct: 130 HGILHRDLTLSNLLLTRNMNIKIADFGLATQLKMPHEKHY 169
Score = 67.4 bits (163), Expect = 8e-11
Identities = 41/106 (38%), Positives = 57/106 (53%), Gaps = 9/106 (8%)
Query: 572 YSTVGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQ 631
Y+ GTP+YI+PEI +G E D WSLG + Y LIG PPF ++T + T K++
Sbjct: 169 YTLCGTPNYISPEIATRSAHGLESDVWSLGCMFYTLLIGRPPFDTDTVKNTLNKVV---- 224
Query: 632 TLQFPDDIHISYEAEDLIRRLLTHS-ENRLGRHGGADEIKAHPFFS 676
+ +S EA+DLI +LL + +RL D HPF S
Sbjct: 225 LADYEMPTFLSIEAKDLIHQLLRRNPADRLSLSSVLD----HPFMS 266
>At2g25880 [D] KOG0580 Serine/threonine protein kinase
Length = 282
Score = 92.0 bits (227), Expect = 3e-18
Identities = 50/147 (34%), Positives = 83/147 (56%)
Query: 346 DFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDSP 405
DF+ K +G+G FG V L ++K + I A+K L K+++ ++ E ++ + P
Sbjct: 18 DFDIGKPLGRGKFGHVYLAREKRSDHIVALKVLFKAQLQQSQVEHQLRREVEIQSHLRHP 77
Query: 406 WVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKLG 465
++ LY F D + +YLI+E+ G+L L + + F+E Y+A A+ H
Sbjct: 78 NILRLYGYFYDQKRVYLILEYAVRGELYKELQKCKYFSERRAATYVASLARALIYCHGKH 137
Query: 466 FIHRDIKPDNILIDIRGHIKLSDFGLS 492
IHRDIKP+N+LI +G +K++DFG S
Sbjct: 138 VIHRDIKPENLLIGAQGELKIADFGWS 164
Score = 59.7 bits (143), Expect = 2e-08
Identities = 37/100 (37%), Positives = 54/100 (54%), Gaps = 7/100 (7%)
Query: 576 GTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQF 635
GT DY+ PE+ + D WSLG + YE L G PPF + ETY++I+ + L+F
Sbjct: 176 GTLDYLPPEMVESVEHDASVDIWSLGILCYEFLYGVPPFEAREHSETYKRIVQVD--LKF 233
Query: 636 PDDIHISYEAEDLIRRLLT-HSENRLGRHGGADEIKAHPF 674
P +S A+DLI ++L S RL H ++ HP+
Sbjct: 234 PPKPIVSSSAKDLISQMLVKESTQRLALH----KLLEHPW 269
>At1g12680 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 470
Score = 91.7 bits (226), Expect = 4e-18
Identities = 52/149 (34%), Positives = 84/149 (55%), Gaps = 8/149 (5%)
Query: 345 DDFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAG-SD 403
DD+ + IGKG FG VR+ + + G +A KTL K E V E +++ S
Sbjct: 105 DDYVFGRNIGKGKFGSVRICKSRKNGTEFACKTLKKGE-------ETVHREVEIMQHLSG 157
Query: 404 SPWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHK 463
P VV+L+ +++S +L+ME GG L+ +++ ++E + +L I H+
Sbjct: 158 HPRVVTLHAVYEESDCFHLVMELCSGGRLIDQMVKVGRYSEQRAANIFKDLMLVINYCHE 217
Query: 464 LGFIHRDIKPDNILIDIRGHIKLSDFGLS 492
+G +HRDIKP+NIL+ G I+L+DFGL+
Sbjct: 218 MGVVHRDIKPENILLTAAGKIQLADFGLA 246
Score = 55.1 bits (131), Expect = 4e-07
Identities = 38/129 (29%), Positives = 62/129 (47%), Gaps = 8/129 (6%)
Query: 550 IHLTMTNRQQMQTWRKSRRLMAYSTV----GTPDYIAPEIFLYQGYGQECDWWSLGAIMY 605
I LT + Q+ + + R+ T+ G+P Y+APE+ L + Y ++ D WS G ++Y
Sbjct: 230 ILLTAAGKIQLADFGLAMRIAKGQTLSGLAGSPAYVAPEV-LSENYSEKVDVWSAGVLLY 288
Query: 606 ECLIGWPPFCSETPQETYRKIMNFEQTLQFPDDIHISYEAEDLIRRLLTHSENRLGRHGG 665
L G PF ++ + I N + +S A DL+ R+LT E+
Sbjct: 289 ALLSGVLPFKGDSLDAIFEAIKNVKLDFNTGVWESVSKPARDLLARMLTREES---ARIT 345
Query: 666 ADEIKAHPF 674
ADE+ HP+
Sbjct: 346 ADEVLRHPW 354
>At4g30960 [T] KOG0583 Serine/threonine protein kinase
Length = 441
Score = 91.3 bits (225), Expect = 5e-18
Identities = 47/142 (33%), Positives = 78/142 (54%), Gaps = 1/142 (0%)
Query: 351 KVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDSPWVVSL 410
+++G G F +V + TGK AMK + K ++ + +K E V+ P +V L
Sbjct: 28 RLLGHGTFAKVYHARNIQTGKSVAMKVVGKEKVVKVGMVDQIKREISVMRMVKHPNIVEL 87
Query: 411 YYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKLGFIHRD 470
+ +Y ME + GG+L + + ++ EDV R Y + I A++ H G HRD
Sbjct: 88 HEVMASKSKIYFAMELVRGGELFAKVAKGRL-REDVARVYFQQLISAVDFCHSRGVYHRD 146
Query: 471 IKPDNILIDIRGHIKLSDFGLS 492
+KP+N+L+D G++K++DFGLS
Sbjct: 147 LKPENLLLDEEGNLKVTDFGLS 168
Score = 55.8 bits (133), Expect = 2e-07
Identities = 32/90 (35%), Positives = 49/90 (53%), Gaps = 5/90 (5%)
Query: 570 MAYSTVGTPDYIAPEIFLYQGY-GQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMN 628
+ ++T GTP Y+APE+ L +GY G + D WS G I++ L G+ PF + YRKI
Sbjct: 179 LLHTTCGTPAYVAPEVILKKGYDGAKADLWSCGVILFVLLAGYLPFQDDNLVNMYRKIYR 238
Query: 629 FEQTLQFPDDIHISYEAEDLIRRLLTHSEN 658
+ F +S +A L+ +LL + N
Sbjct: 239 GD----FKCPGWLSSDARRLVTKLLDPNPN 264
>At3g06030 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 651
Score = 91.3 bits (225), Expect = 5e-18
Identities = 50/147 (34%), Positives = 85/147 (57%), Gaps = 5/147 (3%)
Query: 351 KVIGKGAFGEVRLVQKKDTGKIYAMKTLL-----KSEMYNKDQLAHVKAERDVLAGSDSP 405
++IG GAFG V + D+G++ A+K +L S+ + + ++ E +L P
Sbjct: 72 ELIGCGAFGRVYMGMNLDSGELLAIKQVLIAPSSASKEKTQGHIRELEEEVQLLKNLSHP 131
Query: 406 WVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKLG 465
+V + ++S L ++MEF+PGG + ++L ++ F E V Y + +L +E +H G
Sbjct: 132 NIVRYLGTVRESDSLNILMEFVPGGSISSLLEKFGSFPEPVIIMYTKQLLLGLEYLHNNG 191
Query: 466 FIHRDIKPDNILIDIRGHIKLSDFGLS 492
+HRDIK NIL+D +G I+L+DFG S
Sbjct: 192 IMHRDIKGANILVDNKGCIRLADFGAS 218
Score = 51.2 bits (121), Expect = 6e-06
Identities = 35/108 (32%), Positives = 54/108 (49%), Gaps = 6/108 (5%)
Query: 571 AYSTVGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFE 630
A S GTP ++APE+ L G+ D WS+G + E G PP+ + Q + +++
Sbjct: 230 AKSMKGTPYWMAPEVILQTGHSFSADIWSVGCTVIEMATGKPPWSEQYQQ--FAAVLHIG 287
Query: 631 QTLQFPD-DIHISYEAEDLIRRLLTHSENRLGRHGGADEIKAHPFFSG 677
+T P +S EA+D + + L H E L A E+ HPF +G
Sbjct: 288 RTKAHPPIPEDLSPEAKDFLMKCL-HKEPSL--RLSATELLQHPFVTG 332
>At1g09000 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 666
Score = 90.9 bits (224), Expect = 7e-18
Identities = 49/147 (33%), Positives = 85/147 (57%), Gaps = 5/147 (3%)
Query: 351 KVIGKGAFGEVRLVQKKDTGKIYAMKTLL-----KSEMYNKDQLAHVKAERDVLAGSDSP 405
++IG+GAFG V + D+G++ A+K +L S+ + + ++ E +L P
Sbjct: 73 QLIGRGAFGTVYMGMNLDSGELLAVKQVLIAANFASKEKTQAHIQELEEEVKLLKNLSHP 132
Query: 406 WVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKLG 465
+V + ++ L +++EF+PGG + ++L ++ F E V R Y + +L +E +H
Sbjct: 133 NIVRYLGTVREDDTLNILLEFVPGGSISSLLEKFGPFPESVVRTYTRQLLLGLEYLHNHA 192
Query: 466 FIHRDIKPDNILIDIRGHIKLSDFGLS 492
+HRDIK NIL+D +G IKL+DFG S
Sbjct: 193 IMHRDIKGANILVDNKGCIKLADFGAS 219
Score = 41.2 bits (95), Expect = 0.006
Identities = 31/107 (28%), Positives = 47/107 (42%), Gaps = 4/107 (3%)
Query: 571 AYSTVGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFE 630
A S GTP ++APE+ L G+ D WS+G + E + G P+ S+ +E
Sbjct: 231 AKSMKGTPYWMAPEVILQTGHSFSADIWSVGCTVIEMVTGKAPW-SQQYKEVAAIFFIGT 289
Query: 631 QTLQFPDDIHISYEAEDLIRRLLTHSENRLGRHGGADEIKAHPFFSG 677
P +S +A+D + + L N A E+ HPF G
Sbjct: 290 TKSHPPIPDTLSSDAKDFLLKCLQEVPN---LRPTASELLKHPFVMG 333
>CE21879 [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 328
Score = 90.5 bits (223), Expect = 9e-18
Identities = 49/151 (32%), Positives = 80/151 (52%)
Query: 345 DDFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDS 404
+ F +K IGKGAFG+V L +K + +I + K+ L ++ E +
Sbjct: 4 NQFKPIKSIGKGAFGQVFLAEKLNNPRIKVAMKKINIFGAPKEFLEQIQQEYYIQKNMKH 63
Query: 405 PWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKL 464
+V +Y D+++ YL EF+ GGDL + + + Y+ + + ++ IH
Sbjct: 64 KNIVKMYGMSMDTEFCYLFQEFVTGGDLFEKIDFENGMPVNQVKGYLKQLMSGLKYIHGC 123
Query: 465 GFIHRDIKPDNILIDIRGHIKLSDFGLSTGF 495
G +HRDIKPDN+LI+ +K++DFGLST F
Sbjct: 124 GIVHRDIKPDNLLINSSDALKIADFGLSTRF 154
Score = 33.5 bits (75), Expect = 1.3
Identities = 19/66 (28%), Positives = 37/66 (55%), Gaps = 6/66 (9%)
Query: 567 RRLMAYSTVGTPDYIAPEIFLYQGY-GQECDWWSLGAIMYECLIGWPPFCSETPQET--- 622
+ ++ + +GT ++APE+F + + G D WS G +++ L G P+ + P+E+
Sbjct: 159 KEILLHERIGTTPFMAPELFAKKKHRGPPVDIWSAGILVFSLLTGNLPW--DEPKESDIL 216
Query: 623 YRKIMN 628
Y + MN
Sbjct: 217 YSQWMN 222
>At2g34180 [T] KOG0583 Serine/threonine protein kinase
Length = 502
Score = 90.5 bits (223), Expect = 9e-18
Identities = 46/148 (31%), Positives = 82/148 (55%), Gaps = 1/148 (0%)
Query: 345 DDFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDS 404
D + K++G G+F +V L + +G+ A+K + K ++ H+K E +L
Sbjct: 55 DKYEIGKLLGHGSFAKVYLARNIHSGEDVAIKVIDKEKIVKSGLAGHIKREISILRRVRH 114
Query: 405 PWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKL 464
P++V L +Y++ME++ GG+L + R ++ E R Y + I ++ H
Sbjct: 115 PYIVHLLEVMATKTKIYIVMEYVRGGELYNTVARGRL-REGTARRYFQQLISSVAFCHSR 173
Query: 465 GFIHRDIKPDNILIDIRGHIKLSDFGLS 492
G HRD+K +N+L+D +G++K+SDFGLS
Sbjct: 174 GVYHRDLKLENLLLDDKGNVKVSDFGLS 201
Score = 45.4 bits (106), Expect = 3e-04
Identities = 34/102 (33%), Positives = 49/102 (47%), Gaps = 10/102 (9%)
Query: 576 GTPDYIAPEIFLYQGY-GQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQ 634
GTP Y+APE+ +GY G + D WS G I++ + G+ PF + Y KI Q
Sbjct: 218 GTPAYLAPEVLTRKGYEGAKADIWSCGVILFVLMAGYLPFDDKNILVMYTKIYKG----Q 273
Query: 635 FPDDIHISYEAEDLIRRLL-THSENRLGRHGGADEIKAHPFF 675
F S E L+ R+L T+ + R+ EI H +F
Sbjct: 274 FKCPKWFSPELARLVTRMLDTNPDTRI----TIPEIMKHRWF 311
>At3g29160 [T] KOG0583 Serine/threonine protein kinase
Length = 512
Score = 89.7 bits (221), Expect = 1e-17
Identities = 45/149 (30%), Positives = 82/149 (54%)
Query: 351 KVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDSPWVVSL 410
K +G G+FG+V++ + TG A+K L + ++ N + V+ E +L P ++
Sbjct: 24 KTLGIGSFGKVKIAEHVVTGHKVAIKILNRRKIKNMEMEEKVRREIKILRLFMHPHIIRQ 83
Query: 411 YYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKLGFIHRD 470
Y + + +Y++ME++ G+L ++ ED R + + I +E H+ +HRD
Sbjct: 84 YEVIETTSDIYVVMEYVKSGELFDYIVEKGRLQEDEARNFFQQIISGVEYCHRNMVVHRD 143
Query: 471 IKPDNILIDIRGHIKLSDFGLSTGFHKTH 499
+KP+N+L+D R +IK++DFGLS H
Sbjct: 144 LKPENLLLDSRCNIKIADFGLSNVMRDGH 172
Score = 53.1 bits (126), Expect = 2e-06
Identities = 33/82 (40%), Positives = 44/82 (53%), Gaps = 5/82 (6%)
Query: 573 STVGTPDYIAPEIFLYQGY-GQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQ 631
++ G+P+Y APE+ + Y G E D WS G I+Y L G PF E ++KI
Sbjct: 176 TSCGSPNYAAPEVISGKLYAGPEVDVWSCGVILYALLCGTLPFDDENIPNLFKKIKGGIY 235
Query: 632 TLQFPDDIHISYEAEDLIRRLL 653
TL H+S EA DLI R+L
Sbjct: 236 TL----PSHLSSEARDLIPRML 253
>At1g30270 [T] KOG0583 Serine/threonine protein kinase
Length = 480
Score = 89.7 bits (221), Expect = 1e-17
Identities = 43/142 (30%), Positives = 75/142 (52%)
Query: 351 KVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDSPWVVSL 410
+ +G+G F +V+ + + G A+K + K ++ +A +K E + P V+ +
Sbjct: 35 RTLGEGTFAKVKFARNVENGDNVAIKVIDKEKVLKNKMIAQIKREISTMKLIKHPNVIRM 94
Query: 411 YYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKLGFIHRD 470
+ +Y ++EF+ GG+L + ED R Y + I A++ H G HRD
Sbjct: 95 FEVMASKTKIYFVLEFVTGGELFDKISSNGRLKEDEARKYFQQLINAVDYCHSRGVYHRD 154
Query: 471 IKPDNILIDIRGHIKLSDFGLS 492
+KP+N+L+D G +K+SDFGLS
Sbjct: 155 LKPENLLLDANGALKVSDFGLS 176
Score = 53.9 bits (128), Expect = 9e-07
Identities = 30/85 (35%), Positives = 46/85 (53%), Gaps = 5/85 (5%)
Query: 570 MAYSTVGTPDYIAPEIFLYQGY-GQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMN 628
+ ++T GTP+Y+APE+ +GY G + D WS G I++ + G+ PF Y+KI
Sbjct: 185 LLHTTCGTPNYVAPEVINNKGYDGAKADLWSCGVILFVLMAGYLPFEDSNLTSLYKKIFK 244
Query: 629 FEQTLQFPDDIHISYEAEDLIRRLL 653
E F S A+ LI+R+L
Sbjct: 245 AE----FTCPPWFSASAKKLIKRIL 265
>7302464 [R] KOG0586 Serine/threonine protein kinase
Length = 739
Score = 89.7 bits (221), Expect = 1e-17
Identities = 49/149 (32%), Positives = 82/149 (54%), Gaps = 1/149 (0%)
Query: 347 FNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDSPW 406
+ +K IGKG F +V+L + TGK A+K + K+++ N L + E ++ D P
Sbjct: 151 YKLIKTIGKGNFAKVKLAKHLPTGKEVAIKIIDKTQL-NPGSLQKLFREVRIMKMLDHPN 209
Query: 407 VVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKLGF 466
+V L+ + + LYLIME+ GG++ L+ E R + + A++ H+
Sbjct: 210 IVKLFQVIETEKTLYLIMEYASGGEVFDYLVLHGRMKEKEARVKFRQIVSAVQYCHQKRI 269
Query: 467 IHRDIKPDNILIDIRGHIKLSDFGLSTGF 495
IHRD+K +N+L+D +IK++DFG S F
Sbjct: 270 IHRDLKAENLLLDSELNIKIADFGFSNEF 298
Score = 50.4 bits (119), Expect = 1e-05
Identities = 28/79 (35%), Positives = 45/79 (56%), Gaps = 5/79 (6%)
Query: 576 GTPDYIAPEIFLYQGY-GQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQ 634
G+P Y APE+F + Y G E D WSLG I+Y + G PF T +E +++ + +
Sbjct: 309 GSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIP 368
Query: 635 FPDDIHISYEAEDLIRRLL 653
F ++S + E+L+R+ L
Sbjct: 369 F----YMSTDCENLLRKFL 383
>7290249 [R] KOG0586 Serine/threonine protein kinase
Length = 1398
Score = 89.7 bits (221), Expect = 1e-17
Identities = 44/145 (30%), Positives = 81/145 (55%), Gaps = 1/145 (0%)
Query: 351 KVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDSPWVVSL 410
+ IGKG F V+L + + T A+K + KS++ ++ L V E +++ P ++ L
Sbjct: 145 RTIGKGNFAVVKLARHRITKNEVAIKIIDKSQL-DQTNLQKVYREVEIMKRLKHPHIIKL 203
Query: 411 YYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKLGFIHRD 470
Y + +Y++ E+ G++ + ++ +E RF + I A+E HK G +HRD
Sbjct: 204 YQVMETKNMIYIVSEYASQGEIFDYIAKYGRMSESAARFKFWQIISAVEYCHKKGIVHRD 263
Query: 471 IKPDNILIDIRGHIKLSDFGLSTGF 495
+K +N+L+D+ +IK++DFG S F
Sbjct: 264 LKAENLLLDLNMNIKIADFGFSNHF 288
Score = 52.0 bits (123), Expect = 3e-06
Identities = 35/98 (35%), Positives = 49/98 (49%), Gaps = 8/98 (8%)
Query: 576 GTPDYIAPEIFLYQGY-GQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQ 634
G+P Y APE+F + Y G E D WSLG ++Y + G PF T Q ++++ +
Sbjct: 299 GSPPYAAPEVFEGKQYTGPEIDIWSLGVVLYVLVCGALPFDGSTLQSLRDRVLSGRFRIP 358
Query: 635 FPDDIHISYEAEDLIRRLLTHSENRLGRHGGADEIKAH 672
F +S E E LIRR+L R D+IK H
Sbjct: 359 F----FMSSECEHLIRRMLVLEPT---RRYTIDQIKRH 389
>At5g56580 [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K)
Length = 356
Score = 89.4 bits (220), Expect = 2e-17
Identities = 60/180 (33%), Positives = 97/180 (53%), Gaps = 15/180 (8%)
Query: 316 SEERKNRQLASLGKKESQFXXXXXXXXXXDDFNSVKVIGKGAFGEVRLVQKKDTGKIYAM 375
S+E+++RQ S KE F +D +VKVIGKG+ G V+LV+ K GK +AM
Sbjct: 48 SDEKQSRQSDS---KELDFEITA------EDLETVKVIGKGSGGVVQLVRHKWVGKFFAM 98
Query: 376 KTLLKS--EMYNKDQLAHVKAERDVLAGSDSPWVVSLYYSFQDSQYLYLIMEFLPGGDLM 433
K + + E K + +K + A S P VV Y+SF + L++E++ G L
Sbjct: 99 KVIQMNIQEEIRKQIVQELKINQ---ASSQCPHVVVCYHSFYHNGAFSLVLEYMDRGSLA 155
Query: 434 TMLIRWQIFTEDVTRFYMAECILAIEVIH-KLGFIHRDIKPDNILIDIRGHIKLSDFGLS 492
++ + + E + +L + +H + IHRDIKP N+L++ +G +K+SDFG+S
Sbjct: 156 DVIRQVKTILEPYLAVVCKQVLLGLVYLHNERHVIHRDIKPSNLLVNHKGEVKISDFGVS 215
Score = 36.6 bits (83), Expect = 0.15
Identities = 18/47 (38%), Positives = 24/47 (50%)
Query: 575 VGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQE 621
VGT +Y++PE Y D WSLG + EC IG P+ Q+
Sbjct: 229 VGTYNYMSPERISGSTYDYSSDIWSLGMSVLECAIGRFPYLESEDQQ 275
>Hs9966875 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 357
Score = 89.0 bits (219), Expect = 3e-17
Identities = 48/149 (32%), Positives = 85/149 (56%), Gaps = 5/149 (3%)
Query: 347 FNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDSPW 406
F + +G GAF EV L ++K TGK++A+K + K + K+ + ++ E VL
Sbjct: 23 FEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKALKGKE--SSIENEIAVLRKIKHEN 80
Query: 407 VVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKLGF 466
+V+L ++ +LYL+M+ + GG+L ++ +TE + + + A+ +H++G
Sbjct: 81 IVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGI 140
Query: 467 IHRDIKPDNILI---DIRGHIKLSDFGLS 492
+HRD+KP+N+L D I +SDFGLS
Sbjct: 141 VHRDLKPENLLYYSQDEESKIMISDFGLS 169
Score = 66.6 bits (161), Expect = 1e-10
Identities = 34/102 (33%), Positives = 51/102 (49%), Gaps = 3/102 (2%)
Query: 576 GTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQF 635
GTP Y+APE+ + Y + D WS+G I Y L G+PPF E + + +I+ E
Sbjct: 183 GTPGYVAPEVLAQKPYSKAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDS 242
Query: 636 PDDIHISYEAEDLIRRLLTHSENRLGRHGGADEIKAHPFFSG 677
P IS A+D IR L+ N + ++ HP+ +G
Sbjct: 243 PYWDDISDSAKDFIRNLMEKDPN---KRYTCEQAARHPWIAG 281
>Hs21361433 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 970
Score = 89.0 bits (219), Expect = 3e-17
Identities = 49/160 (30%), Positives = 84/160 (51%), Gaps = 1/160 (0%)
Query: 345 DDFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDS 404
+DF ++GKG+F V + +G A+K + K MY + V+ E +
Sbjct: 10 EDFKVGNLLGKGSFAGVYRAESIHSGLEVAIKMIDKKAMYKAGMVQRVQNEVKIHCQLKH 69
Query: 405 PWVVSLYYSFQDSQYLYLIMEFLPGGDLMTML-IRWQIFTEDVTRFYMAECILAIEVIHK 463
P ++ LY F+DS Y+YL++E G++ L R + F+E+ R +M + I + +H
Sbjct: 70 PSILELYNYFEDSNYVYLVLEMCHNGEMNRYLKNRVKPFSENEARHFMHQIITGMLYLHS 129
Query: 464 LGFIHRDIKPDNILIDIRGHIKLSDFGLSTGFHKTHDSSY 503
G +HRD+ N+L+ +IK++DFGL+T H+ Y
Sbjct: 130 HGILHRDLTLSNLLLTRNMNIKIADFGLATQLKMPHEKHY 169
Score = 67.4 bits (163), Expect = 8e-11
Identities = 41/106 (38%), Positives = 57/106 (53%), Gaps = 9/106 (8%)
Query: 572 YSTVGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQ 631
Y+ GTP+YI+PEI +G E D WSLG + Y LIG PPF ++T + T K++
Sbjct: 169 YTLCGTPNYISPEIATRSAHGLESDVWSLGCMFYTLLIGRPPFDTDTVKNTLNKVV---- 224
Query: 632 TLQFPDDIHISYEAEDLIRRLLTHS-ENRLGRHGGADEIKAHPFFS 676
+ +S EA+DLI +LL + +RL D HPF S
Sbjct: 225 LADYEMPTFLSIEAKDLIHQLLRRNPADRLSLSSVLD----HPFMS 266
>At2g20040 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 261
Score = 88.6 bits (218), Expect = 3e-17
Identities = 56/150 (37%), Positives = 85/150 (56%), Gaps = 12/150 (8%)
Query: 548 DAIHLTMTNRQQMQTWRKSRRLMA---YSTVGTPDYIAPEIFLYQGYGQECDWWSLGAIM 604
+ + L + Q+ +R +++L ++ G DY+APEI +G+G DWW+LG ++
Sbjct: 76 ELLMLDQSGYLQIVDFRFAKKLSGERTFTICGNADYLAPEIVQGKGHGYAADWWALGVLI 135
Query: 605 YECLIGWPPFCS--ETPQETYRKIMNFEQTLQFPDDIHISYEAEDLIRRLLTHSEN-RLG 661
Y L G PF S E+ +T++KI + L FP +S EAEDLI +LL EN R G
Sbjct: 136 YYMLEGEMPFGSWRESELDTFQKIAKGQ--LTFPR--VLSSEAEDLITKLLEVDENLRFG 191
Query: 662 RHGGADEIKAHPFFSGVDWNTI--RQVEAP 689
GG + IK HP+F+G+ W I R+ + P
Sbjct: 192 SQGGPESIKKHPWFNGLKWEAISNREFQVP 221
Score = 33.1 bits (74), Expect = 1.6
Identities = 15/46 (32%), Positives = 25/46 (53%)
Query: 444 EDVTRFYMAECILAIEVIHKLGFIHRDIKPDNILIDIRGHIKLSDF 489
E RF + AIE IHK + R P+ +++D G++++ DF
Sbjct: 46 ESSVRFITGSLVSAIEDIHKNEILFRGSSPELLMLDQSGYLQIVDF 91
>CE27768 [R] KOG0586 Serine/threonine protein kinase
Length = 1096
Score = 88.2 bits (217), Expect = 4e-17
Identities = 48/149 (32%), Positives = 80/149 (53%), Gaps = 1/149 (0%)
Query: 347 FNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDSPW 406
+ +K IGKG F +V+L + TG A+K + K+ + N L + E ++ D P
Sbjct: 122 YKLLKTIGKGNFAKVKLAKHVITGHEVAIKIIDKTAL-NPSSLQKLFREVKIMKQLDHPN 180
Query: 407 VVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKLGF 466
+V LY + Q LYL++E+ GG++ L+ E R + + A++ +H
Sbjct: 181 IVKLYQVMETEQTLYLVLEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYLHSKNI 240
Query: 467 IHRDIKPDNILIDIRGHIKLSDFGLSTGF 495
IHRD+K +N+L+D +IK++DFG S F
Sbjct: 241 IHRDLKAENLLLDQDMNIKIADFGFSNTF 269
Score = 48.9 bits (115), Expect = 3e-05
Identities = 27/85 (31%), Positives = 47/85 (54%), Gaps = 5/85 (5%)
Query: 576 GTPDYIAPEIFLYQGY-GQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQ 634
G+P Y APE+F + Y G E D WSLG I+Y + G PF + +E +++ + +
Sbjct: 280 GSPPYAAPELFSGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIP 339
Query: 635 FPDDIHISYEAEDLIRRLLTHSENR 659
F ++S + E+L+++ L + R
Sbjct: 340 F----YMSTDCENLLKKFLVINPQR 360
>CE23838 [R] KOG0586 Serine/threonine protein kinase
Length = 1192
Score = 88.2 bits (217), Expect = 4e-17
Identities = 48/149 (32%), Positives = 80/149 (53%), Gaps = 1/149 (0%)
Query: 347 FNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDSPW 406
+ +K IGKG F +V+L + TG A+K + K+ + N L + E ++ D P
Sbjct: 170 YKLLKTIGKGNFAKVKLAKHVITGHEVAIKIIDKTAL-NPSSLQKLFREVKIMKQLDHPN 228
Query: 407 VVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKLGF 466
+V LY + Q LYL++E+ GG++ L+ E R + + A++ +H
Sbjct: 229 IVKLYQVMETEQTLYLVLEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYLHSKNI 288
Query: 467 IHRDIKPDNILIDIRGHIKLSDFGLSTGF 495
IHRD+K +N+L+D +IK++DFG S F
Sbjct: 289 IHRDLKAENLLLDQDMNIKIADFGFSNTF 317
Score = 48.9 bits (115), Expect = 3e-05
Identities = 27/85 (31%), Positives = 47/85 (54%), Gaps = 5/85 (5%)
Query: 576 GTPDYIAPEIFLYQGY-GQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQ 634
G+P Y APE+F + Y G E D WSLG I+Y + G PF + +E +++ + +
Sbjct: 328 GSPPYAAPELFSGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIP 387
Query: 635 FPDDIHISYEAEDLIRRLLTHSENR 659
F ++S + E+L+++ L + R
Sbjct: 388 F----YMSTDCENLLKKFLVINPQR 408
>At3g01090 [T] KOG0583 Serine/threonine protein kinase
Length = 512
Score = 88.2 bits (217), Expect = 4e-17
Identities = 44/149 (29%), Positives = 81/149 (53%)
Query: 351 KVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDSPWVVSL 410
+ +G G+FG V++ + TG A+K L + ++ N + V+ E +L P ++ L
Sbjct: 23 RTLGIGSFGRVKIAEHALTGHKVAIKILNRRKIKNMEMEEKVRREIKILRLFMHPHIIRL 82
Query: 411 YYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKLGFIHRD 470
Y + +YL+ME++ G+L ++ ED R + + I +E H+ +HRD
Sbjct: 83 YEVIETPTDIYLVMEYVNSGELFDYIVEKGRLQEDEARNFFQQIISGVEYCHRNMVVHRD 142
Query: 471 IKPDNILIDIRGHIKLSDFGLSTGFHKTH 499
+KP+N+L+D + ++K++DFGLS H
Sbjct: 143 LKPENLLLDSKCNVKIADFGLSNIMRDGH 171
Score = 52.8 bits (125), Expect = 2e-06
Identities = 37/104 (35%), Positives = 51/104 (48%), Gaps = 8/104 (7%)
Query: 573 STVGTPDYIAPEIFLYQGY-GQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQ 631
++ G+P+Y APE+ + Y G E D WS G I+Y L G PF E ++KI
Sbjct: 175 TSCGSPNYAAPEVISGKLYAGPEVDVWSCGVILYALLCGTLPFDDENIPNLFKKIKGGIY 234
Query: 632 TLQFPDDIHISYEAEDLIRRLLTHSENRLGRHGGADEIKAHPFF 675
TL H+S A DLI R+L + EI+ HP+F
Sbjct: 235 TL----PSHLSPGARDLIPRMLVVDPM---KRVTIPEIRQHPWF 271
>Hs20545245 [D] KOG0588 Serine/threonine protein kinase
Length = 795
Score = 87.8 bits (216), Expect = 6e-17
Identities = 50/176 (28%), Positives = 96/176 (54%), Gaps = 2/176 (1%)
Query: 318 ERKNRQLASLGKKESQFXXXXXXXXXXDDFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKT 377
ERK+ ++A G +E + + K +GKG G V+L TG+ A+K
Sbjct: 23 ERKD-EVAGGGGEEEEAEERGRHAQYVGPYRLEKTLGKGQTGLVKLGVHCITGQKVAIK- 80
Query: 378 LLKSEMYNKDQLAHVKAERDVLAGSDSPWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLI 437
++ E ++ L V+ E +L + P V+ L+ +++ +YLYL++E + GG+L L+
Sbjct: 81 IVNREKLSESVLMKVEREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLV 140
Query: 438 RWQIFTEDVTRFYMAECILAIEVIHKLGFIHRDIKPDNILIDIRGHIKLSDFGLST 493
+ T R + + + A++ H HRD+KP+N+L+D + +I+++DFG+++
Sbjct: 141 KKGRLTPKEARKFFRQIVSALDFCHSYSICHRDLKPENLLLDEKNNIRIADFGMAS 196
Score = 43.1 bits (100), Expect = 0.002
Identities = 29/109 (26%), Positives = 51/109 (46%), Gaps = 14/109 (12%)
Query: 573 STVGTPDYIAPEIFLYQGY-GQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMN--F 629
++ G+P Y PE+ + Y G+ D WS G I++ L+G PF + ++ K+ F
Sbjct: 206 TSCGSPHYACPEVIKGEKYDGRRADMWSCGVILFALLVGALPFDDDNLRQLLEKVKRGVF 265
Query: 630 EQTLQFPDDIHISYEAEDLIRRLL-THSENRLGRHGGADEIKAHPFFSG 677
P D + L+R ++ E RL ++I+ HP++ G
Sbjct: 266 HMPHFIPPD------CQSLLRGMIEVEPEKRL----SLEQIQKHPWYLG 304
>Hs14754789 [OUT] KOG0595 Serine/threonine-protein kinase involved in autophagy
Length = 257
Score = 87.8 bits (216), Expect = 6e-17
Identities = 52/151 (34%), Positives = 82/151 (53%), Gaps = 4/151 (2%)
Query: 345 DDFNSVKVIGKGAFGEV-RLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSD 403
D F + +G G + V + KKDT ++ A+K + K + NK + ++ E ++L G
Sbjct: 55 DGFILTERLGSGTYATVYKAYAKKDTREVVAIKCVAKKSL-NKASVENLLTEIEILKGIR 113
Query: 404 SPWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHK 463
P +V L DS +YLIMEF GGDL + +I E V R +M + A++ +H+
Sbjct: 114 HPHIVQLKDFQWDSDNIYLIMEFCAGGDLSRFIHTRRILPEKVARVFMQQLASALQFLHE 173
Query: 464 LGFIHRDIKPDNILIDI--RGHIKLSDFGLS 492
H D+KP NIL+ + H+KL+DFG +
Sbjct: 174 RNISHLDLKPQNILLSSLEKPHLKLADFGFA 204
Score = 34.7 bits (78), Expect = 0.56
Identities = 17/48 (35%), Positives = 24/48 (49%), Gaps = 5/48 (10%)
Query: 558 QQMQTWRKSRRLMAYSTVGTPDYIAPEIFLYQGYGQECDWWSLGAIMY 605
Q M W + L G+P Y+APE+ + Y D WS+G I+Y
Sbjct: 205 QHMSPWDEKHVLR-----GSPLYMAPEMVCQRQYDARVDLWSMGVILY 247
>At4g29810 [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K)
Length = 363
Score = 87.8 bits (216), Expect = 6e-17
Identities = 53/151 (35%), Positives = 83/151 (54%), Gaps = 7/151 (4%)
Query: 346 DFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAH--VKAERDVLAGSD 403
D + VKVIGKG+ G V+LVQ K TG+ +A+K + N D+ + E + S
Sbjct: 69 DLDMVKVIGKGSSGVVQLVQHKWTGQFFALKVI----QLNIDEAIRKAIAQELKINQSSQ 124
Query: 404 SPWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHK 463
P +V+ Y SF D+ + LI+E++ GG L L + + + + + +H
Sbjct: 125 CPNLVTSYQSFYDNGAISLILEYMDGGSLADFLKSVKAIPDSYLSAIFRQVLQGLIYLHH 184
Query: 464 -LGFIHRDIKPDNILIDIRGHIKLSDFGLST 493
IHRD+KP N+LI+ RG +K++DFG+ST
Sbjct: 185 DRHIIHRDLKPSNLLINHRGEVKITDFGVST 215
Score = 53.9 bits (128), Expect = 9e-07
Identities = 31/116 (26%), Positives = 55/116 (46%), Gaps = 2/116 (1%)
Query: 570 MAYSTVGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNF 629
+A + VGT +Y++PE + YG + D WSLG ++ EC G P+ +ET+ +
Sbjct: 223 LANTFVGTYNYMSPERIVGNKYGNKSDIWSLGLVVLECATGKFPYAPPNQEETWTSVFEL 282
Query: 630 EQTL--QFPDDIHISYEAEDLIRRLLTHSENRLGRHGGADEIKAHPFFSGVDWNTI 683
+ + Q P + + +L + T + A E+ HPF + D++ I
Sbjct: 283 MEAIVDQPPPALPSGNFSPELSSFISTCLQKDPNSRSSAKELMEHPFLNKYDYSGI 338
>7298652 [D] KOG0615 Serine/threonine protein kinase Chk2 and related
proteins
Length = 459
Score = 87.8 bits (216), Expect = 6e-17
Identities = 48/149 (32%), Positives = 82/149 (54%), Gaps = 9/149 (6%)
Query: 353 IGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMY------NKDQLAHVKAERDVLAGSDSPW 406
+G GA+G VRLV T + +AMK + K+ + N V E ++ P
Sbjct: 163 LGSGAYGLVRLVYDTRTCQQFAMKIVKKNMLSGARPSTNFSDPDRVLNEAKIMKNLSHPC 222
Query: 407 VVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKLGF 466
VV ++ +Y+++EF+ GGDL+ +I ++ +ED+++ Y + A++ +H G
Sbjct: 223 VVRMHDIVDKPDSVYMVLEFMRGGDLLNRIISNKLLSEDISKLYFYQMCHAVKYLHDRGI 282
Query: 467 IHRDIKPDNILIDIRGH---IKLSDFGLS 492
HRD+KPDN+L++ +K+SDFGLS
Sbjct: 283 THRDLKPDNVLLETNDEETLLKVSDFGLS 311
Score = 47.4 bits (111), Expect = 8e-05
Identities = 27/81 (33%), Positives = 41/81 (50%), Gaps = 3/81 (3%)
Query: 576 GTPDYIAPEIFLYQG---YGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQT 632
GTP Y+APE+ + G Y ++ D WSLG +++ CL G PF E ++I
Sbjct: 325 GTPLYVAPEVLITGGREAYTKKVDIWSLGVVLFTCLSGTLPFSDEYGTPAAQQIKKGRFA 384
Query: 633 LQFPDDIHISYEAEDLIRRLL 653
P +S A+ LI ++L
Sbjct: 385 YGHPSWKSVSQRAKLLINQML 405
>SPAC57A10.02 [D] KOG0588 Serine/threonine protein kinase
Length = 775
Score = 87.4 bits (215), Expect = 7e-17
Identities = 41/141 (29%), Positives = 79/141 (55%)
Query: 353 IGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDSPWVVSLYY 412
+G G RL + ++TG++ +K ++ Q A ++ E +L + P V+ L
Sbjct: 16 LGSGGPNSSRLAKHRETGQLAVVKPIVGWSELTSSQQARIEGELVLLRLIEHPNVLQLID 75
Query: 413 SFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKLGFIHRDIK 472
+ L++++E++PGG+L ++R FTE T ++ + + +E HKL HRD+K
Sbjct: 76 VISAQEQLFVVVEYMPGGELFDCMLRKGSFTEQDTAKFLWQILCGLEYCHKLHICHRDLK 135
Query: 473 PDNILIDIRGHIKLSDFGLST 493
P+N+ +D G IK+ +FG+++
Sbjct: 136 PENLYLDAHGSIKIGEFGMAS 156
Score = 44.7 bits (104), Expect = 5e-04
Identities = 33/106 (31%), Positives = 52/106 (48%), Gaps = 10/106 (9%)
Query: 573 STVGTPDYIAPEIFLYQGY-GQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQ 631
++ G+P Y +PEI + + Y G D WS G I + L G PF + + K+
Sbjct: 166 TSCGSPHYASPEIIMGRSYDGCASDIWSCGIIFFALLTGKLPFDDDNIRSLLLKVCQG-- 223
Query: 632 TLQFPDDIHISYEAEDLIRRLL-THSENRLGRHGGADEIKAHPFFS 676
QF +IS +A+ L+ R+L S R+ ++I+ HPF S
Sbjct: 224 --QFEMPSNISPQAQHLLYRMLDVDSSTRI----TMEQIREHPFLS 263
>Hs14196445 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 476
Score = 87.4 bits (215), Expect = 7e-17
Identities = 47/149 (31%), Positives = 87/149 (57%), Gaps = 6/149 (4%)
Query: 347 FNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDSPW 406
F ++V+G GAF EV LV+++ TGK++A+K + KS + L + E VL
Sbjct: 23 FIFMEVLGSGAFSEVFLVKQRLTGKLFALKCIKKSPAFRDSSLEN---EIAVLKKIKHEN 79
Query: 407 VVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKLGF 466
+V+L ++ + + YL+M+ + GG+L ++ ++TE + + + A++ +H+ G
Sbjct: 80 IVTLEDIYESTTHYYLVMQLVSGGELFDRILERGVYTEKDASLVIQQVLSAVKYLHENGI 139
Query: 467 IHRDIKPDNILI---DIRGHIKLSDFGLS 492
+HRD+KP+N+L + I ++DFGLS
Sbjct: 140 VHRDLKPENLLYLTPEENSKIMITDFGLS 168
Score = 63.5 bits (153), Expect = 1e-09
Identities = 35/102 (34%), Positives = 49/102 (47%), Gaps = 3/102 (2%)
Query: 576 GTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQF 635
GTP Y+APE+ + Y + D WS+G I Y L G+PPF ET + + KI +
Sbjct: 181 GTPGYVAPEVLAQKPYSKAVDCWSIGVITYILLCGYPPFYEETESKLFEKIKEGYYEFES 240
Query: 636 PDDIHISYEAEDLIRRLLTHSENRLGRHGGADEIKAHPFFSG 677
P IS A+D I LL N ++ +HP+ G
Sbjct: 241 PFWDDISESAKDFICHLLEKDPN---ERYTCEKALSHPWIDG 279
>At4g14580 [T] KOG0583 Serine/threonine protein kinase
Length = 426
Score = 87.4 bits (215), Expect = 7e-17
Identities = 44/141 (31%), Positives = 78/141 (55%), Gaps = 1/141 (0%)
Query: 353 IGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAG-SDSPWVVSLY 411
+G G+F +V + + TG++ A+K + K + + + E + + + P V+ ++
Sbjct: 27 LGSGSFAKVHVARSISTGELVAIKIIDKQKTIDSGMEPRIIREIEAMRRLHNHPNVLKIH 86
Query: 412 YSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKLGFIHRDI 471
+YL++E+ GG+L T LIR+ E R Y + A+ H+ G HRD+
Sbjct: 87 EVMATKSKIYLVVEYAAGGELFTKLIRFGRLNESAARRYFQQLASALSFCHRDGIAHRDV 146
Query: 472 KPDNILIDIRGHIKLSDFGLS 492
KP N+L+D +G++K+SDFGLS
Sbjct: 147 KPQNLLLDKQGNLKVSDFGLS 167
Score = 49.7 bits (117), Expect = 2e-05
Identities = 31/90 (34%), Positives = 46/90 (50%), Gaps = 5/90 (5%)
Query: 565 KSRRLMAYSTVGTPDYIAPEIFLYQGY-GQECDWWSLGAIMYECLIGWPPFCSETPQETY 623
+S + ++ GTP Y APE+ +GY G + D WS G ++ L G+ PF Y
Sbjct: 173 RSNNGLLHTACGTPAYTAPEVIAQRGYDGAKADAWSCGVFLFVLLAGYVPFDDANIVAMY 232
Query: 624 RKIMNFEQTLQFPDDIHISYEAEDLIRRLL 653
RKI ++ +FP IS A +I +LL
Sbjct: 233 RKI--HKRDYRFPS--WISKPARSIIYKLL 258
>Hs21389411 [T] KOG0694 Serine/threonine protein kinase
Length = 274
Score = 87.0 bits (214), Expect = 1e-16
Identities = 48/141 (34%), Positives = 81/141 (57%), Gaps = 1/141 (0%)
Query: 352 VIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDSPWVVSLY 411
++ KG+FG V V ++A+K + K ++ +D + K E + + P+V SL
Sbjct: 112 LVAKGSFGTVLKVLDCTQKAVFAVKVVPKVKVLQRDTVRQCKEEVSIQRQINHPFVHSLG 171
Query: 412 YSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKLGFIHRDI 471
S+Q ++L+++ + DL ++ F E R + AE +L + +H LG +HRD+
Sbjct: 172 DSWQGKRHLFIMCSYC-STDLYSLWSAVGCFPEASIRLFAAELVLVLCYLHDLGIMHRDV 230
Query: 472 KPDNILIDIRGHIKLSDFGLS 492
K +NIL+D RGH+KL+DFGLS
Sbjct: 231 KMENILLDERGHLKLTDFGLS 251
>At5g39440 [T] KOG0583 Serine/threonine protein kinase
Length = 494
Score = 87.0 bits (214), Expect = 1e-16
Identities = 46/149 (30%), Positives = 78/149 (51%)
Query: 351 KVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDSPWVVSL 410
K +G G+F +V+L TG A+K L +S++ N V+ E +L P ++
Sbjct: 23 KTLGHGSFAKVKLALHVATGHKVAIKILNRSKIKNMGIEIKVQREIKILRFLMHPHIIRQ 82
Query: 411 YYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKLGFIHRD 470
Y + +Y++ME++ G+L ++ ED R + I +E H+ +HRD
Sbjct: 83 YEVIETPNDIYVVMEYVKSGELFDYIVEKGKLQEDEARHLFQQIISGVEYCHRNMIVHRD 142
Query: 471 IKPDNILIDIRGHIKLSDFGLSTGFHKTH 499
+KP+N+L+D + +IK+ DFGLS H H
Sbjct: 143 LKPENVLLDSQCNIKIVDFGLSNVMHDGH 171
Score = 58.5 bits (140), Expect = 4e-08
Identities = 37/104 (35%), Positives = 53/104 (50%), Gaps = 7/104 (6%)
Query: 573 STVGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQT 632
++ G+P+Y APE+ + YG + D WS G I+Y L G PF E + KI T
Sbjct: 175 TSCGSPNYAAPEVISGKPYGPDVDIWSCGVILYALLCGTLPFDDENIPNVFEKIKRGMYT 234
Query: 633 LQFPDDIHISYEAEDLIRRLLTHSENRLGRHGGADEIKAHPFFS 676
L P+ H+S+ A DLI R+L EI+ HP+F+
Sbjct: 235 L--PN--HLSHFARDLIPRMLMVDPT---MRISITEIRQHPWFN 271
>At5g19360 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 523
Score = 87.0 bits (214), Expect = 1e-16
Identities = 49/151 (32%), Positives = 82/151 (53%), Gaps = 5/151 (3%)
Query: 351 KVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAG-SDSPWVVS 409
K +G+G FG L +K TG +A KT+ K ++ NK+ + V+ E ++ + P +V
Sbjct: 72 KELGRGQFGVTHLCTQKATGLQFACKTIAKRKLVNKEDIEDVRREVQIMHHLTGQPNIVE 131
Query: 410 LYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKLGFIHR 469
L +++D ++L+ME GG+L +I ++E + + I H +G IHR
Sbjct: 132 LKGAYEDKHSVHLVMELCAGGELFDRIIAKGHYSERAAASLLRTIVQIIHTCHSMGVIHR 191
Query: 470 DIKPDNILI---DIRGHIKLSDFGLSTGFHK 497
D+KP+N L+ D +K +DFGLS F+K
Sbjct: 192 DLKPENFLLLSKDENSPLKATDFGLSV-FYK 221
Score = 55.5 bits (132), Expect = 3e-07
Identities = 39/119 (32%), Positives = 62/119 (51%), Gaps = 13/119 (10%)
Query: 575 VGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQ 634
VG+ YIAPE+ L + YG E D WS+G ++Y L G PPF +E+ + I++ +
Sbjct: 230 VGSAYYIAPEV-LRRKYGPEADIWSIGVMLYILLCGVPPFWAESENGIFNAILSGQVDFS 288
Query: 635 FPDDIHISYEAEDLIRRLL-THSENRLGRHGGADEIKAHPFFSGVDWNTIRQVEAPYIP 692
IS +A+DL+R++L + + RL A ++ HP+ EAP +P
Sbjct: 289 SDPWPVISPQAKDLVRKMLNSDPKQRL----TAAQVLNHPWIK-------EDGEAPDVP 336
>At5g12180 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 528
Score = 87.0 bits (214), Expect = 1e-16
Identities = 48/151 (31%), Positives = 82/151 (53%), Gaps = 5/151 (3%)
Query: 351 KVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAG-SDSPWVVS 409
K +G+G FG L +K TG +A KT+ K ++ NK+ + V+ E ++ + P +V
Sbjct: 77 KELGRGQFGVTHLCTQKATGHQFACKTIAKRKLVNKEDIEDVRREVQIMHHLTGQPNIVE 136
Query: 410 LYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKLGFIHR 469
L +++D ++L+ME GG+L +I ++E + + + H +G IHR
Sbjct: 137 LKGAYEDKHSVHLVMELCAGGELFDRIIAKGHYSERAAASLLRTIVQIVHTCHSMGVIHR 196
Query: 470 DIKPDNILI---DIRGHIKLSDFGLSTGFHK 497
D+KP+N L+ D +K +DFGLS F+K
Sbjct: 197 DLKPENFLLLNKDENSPLKATDFGLSV-FYK 226
Score = 53.9 bits (128), Expect = 9e-07
Identities = 38/119 (31%), Positives = 60/119 (49%), Gaps = 13/119 (10%)
Query: 575 VGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQ 634
VG+ YIAPE+ L + YG E D WS+G ++Y L G PPF +E+ + I+
Sbjct: 235 VGSAYYIAPEV-LKRKYGPEADIWSIGVMLYILLCGVPPFWAESENGIFNAILRGHVDFS 293
Query: 635 FPDDIHISYEAEDLIRRLL-THSENRLGRHGGADEIKAHPFFSGVDWNTIRQVEAPYIP 692
IS +A+DL++++L + + RL A ++ HP+ EAP +P
Sbjct: 294 SDPWPSISPQAKDLVKKMLNSDPKQRL----TAAQVLNHPWIK-------EDGEAPDVP 341
>At3g15220 [T] KOG0201 Serine/threonine protein kinase
Length = 690
Score = 87.0 bits (214), Expect = 1e-16
Identities = 48/152 (31%), Positives = 83/152 (54%), Gaps = 2/152 (1%)
Query: 347 FNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKAERDVLAGSDSPW 406
F+ +++IG+G+FG+V KD K A+K + E ++D++ ++ E VL+ P+
Sbjct: 15 FSQIELIGRGSFGDVYKAFDKDLNKEVAIKVIDLEE--SEDEIEDIQKEISVLSQCRCPY 72
Query: 407 VVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIRWQIFTEDVTRFYMAECILAIEVIHKLGF 466
+ Y S+ L++IME++ GG + +L E + + A+E +H G
Sbjct: 73 ITEYYGSYLHQTKLWIIMEYMAGGSVADLLQSNNPLDETSIACITRDLLHAVEYLHNEGK 132
Query: 467 IHRDIKPDNILIDIRGHIKLSDFGLSTGFHKT 498
IHRDIK NIL+ G +K++DFG+S +T
Sbjct: 133 IHRDIKAANILLSENGDVKVADFGVSAQLTRT 164
Score = 38.5 bits (88), Expect = 0.039
Identities = 19/46 (41%), Positives = 26/46 (56%), Gaps = 1/46 (2%)
Query: 575 VGTPDYIAPEIFLY-QGYGQECDWWSLGAIMYECLIGWPPFCSETP 619
VGTP ++APE+ +GY ++ D WSLG + E G PP P
Sbjct: 172 VGTPFWMAPEVIQNSEGYNEKADIWSLGITVIEMAKGEPPLADLHP 217
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.318 0.134 0.402
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 38,795,343
Number of Sequences: 60738
Number of extensions: 1514174
Number of successful extensions: 9143
Number of sequences better than 10.0: 1940
Number of HSP's better than 10.0 without gapping: 1626
Number of HSP's successfully gapped in prelim test: 314
Number of HSP's that attempted gapping in prelim test: 4092
Number of HSP's gapped (non-prelim): 3656
length of query: 762
length of database: 30,389,216
effective HSP length: 114
effective length of query: 648
effective length of database: 23,465,084
effective search space: 15205374432
effective search space used: 15205374432
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)