ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIV2078 good Q KOG1208 Secondary metabolites biosynthesis, transport and catabolism Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIV2078 710608 709394 -405
(405 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YNL181w [Q] KOG1208 Dehydrogenases with different specificities ... 487 e-137
SPAC19A8.06 [Q] KOG1208 Dehydrogenases with different specificit... 205 9e-53
7304180 [Q] KOG1208 Dehydrogenases with different specificities ... 94 3e-19
7304178 [Q] KOG1208 Dehydrogenases with different specificities ... 92 2e-18
7304181 [Q] KOG1208 Dehydrogenases with different specificities ... 91 3e-18
Hs21553325 [Q] KOG1208 Dehydrogenases with different specificiti... 85 2e-16
Hs10190746 [Q] KOG1208 Dehydrogenases with different specificiti... 79 1e-14
7304177 [Q] KOG1208 Dehydrogenases with different specificities ... 78 2e-14
CE20634 [Q] KOG1208 Dehydrogenases with different specificities ... 77 6e-14
7300387 [Q] KOG1208 Dehydrogenases with different specificities ... 74 3e-13
Hs19923931 [Q] KOG1208 Dehydrogenases with different specificiti... 73 7e-13
CE27908 [Q] KOG1208 Dehydrogenases with different specificities ... 72 1e-12
7304176 [Q] KOG1208 Dehydrogenases with different specificities ... 72 2e-12
CE16253 [Q] KOG1208 Dehydrogenases with different specificities ... 70 6e-12
7290709 [Q] KOG1208 Dehydrogenases with different specificities ... 70 6e-12
Hs20070272 [Q] KOG1208 Dehydrogenases with different specificiti... 69 1e-11
At4g09750 [Q] KOG1208 Dehydrogenases with different specificitie... 69 2e-11
At2g37540 [Q] KOG1208 Dehydrogenases with different specificitie... 68 2e-11
Hs18582884 [Q] KOG1208 Dehydrogenases with different specificiti... 65 1e-10
Hs21389583 [Q] KOG1208 Dehydrogenases with different specificiti... 62 2e-09
CE08181 [Q] KOG1208 Dehydrogenases with different specificities ... 60 4e-09
CE01219 [Q] KOG1208 Dehydrogenases with different specificities ... 60 8e-09
At4g24050 [Q] KOG1208 Dehydrogenases with different specificitie... 55 2e-07
At1g64590 [Q] KOG1208 Dehydrogenases with different specificitie... 54 4e-07
7300378 [Q] KOG1208 Dehydrogenases with different specificities ... 52 2e-06
At4g11410 [Q] KOG1208 Dehydrogenases with different specificitie... 52 2e-06
At5g50130 [Q] KOG1208 Dehydrogenases with different specificitie... 50 8e-06
>YNL181w [Q] KOG1208 Dehydrogenases with different specificities (related to
short-chain alcohol dehydrogenases)
Length = 407
Score = 487 bits (1254), Expect = e-137
Identities = 233/386 (60%), Positives = 299/386 (77%), Gaps = 7/386 (1%)
Query: 1 MPLNILGAAVFDGVDSIPYLRPVLTWSPYLAFIGAIKYWSGGPSNTWERNLHGKLYIVTG 60
MPLNI+G A+ DG D IPY + + +PY+ GAIKYWS GPSNTWER LHGK+Y+VTG
Sbjct: 1 MPLNIIGTALLDGTDKIPYYQTIKKVAPYVLATGAIKYWSRGPSNTWERKLHGKVYLVTG 60
Query: 61 GTTQSMGTSVVLDMARRGAQMIVLCRKIDEWSEEWCEQMRELTGNELIYLEQCDLSDLFE 120
T+Q MGTSV MA GAQ+I+L R++DEW EWCE++RE T NELI++E+CDLS+L+E
Sbjct: 61 ATSQGMGTSVAYKMAELGAQLIILTREVDEWVTEWCEELREKTKNELIFVEKCDLSNLWE 120
Query: 121 VRKFATKWLDNAPPRRLDGIIVMSGDCEPWGLRK-----KKTSTDGIEIQMATNYAGVFH 175
+RKFAT WLDN+PPRRLDG+IVMSGD EPWG+ K +++S DG+E+Q+ATNY +FH
Sbjct: 121 IRKFATSWLDNSPPRRLDGVIVMSGDMEPWGIPKISLPQRRSSKDGLELQIATNYVAIFH 180
Query: 176 LLNLMKPSFKAQPPDRDVRIIVTTCFLQAMGKCNVEDPLWLHAPFKNSRELFSSSKLQLS 235
LLNL++PSFKAQPPDRDVRII+ TC+LQ +G N+EDPLW +A +K++ + F+SSKLQL
Sbjct: 181 LLNLLQPSFKAQPPDRDVRIILATCWLQVVGDINIEDPLWQNAKYKSALKFFASSKLQLG 240
Query: 236 LAMLHLQRLLITEAGNSAKDG--RSGKNVTVTVVQPGLMRSPSLRRVVSNGSXXXXXXXX 293
L+M+ LQR L + N +G R+GKNVT+T+VQPG MRS SLRRV+SNGS
Sbjct: 241 LSMMELQRRLTEDIKNQKTNGPERTGKNVTITMVQPGTMRSNSLRRVISNGSVVLLIILY 300
Query: 294 XXXXXPFLWLLTKSGYRGAQTIIYSITTPELEEVNRTDDEVKYIANCSIVNFARKEFYDK 353
P LWL TKSG RG Q+ +Y++ TPELEEVN D +VKYI++CSIV FARKEF D+
Sbjct: 301 CILLYPILWLFTKSGRRGDQSFLYALMTPELEEVNLKDTKVKYISDCSIVKFARKEFDDE 360
Query: 354 ELQEKLYENTIKQIESVEKKMAAQRN 379
ELQ+KL++NT + I +EKK+AA+RN
Sbjct: 361 ELQKKLFDNTERDILQLEKKVAAKRN 386
>SPAC19A8.06 [Q] KOG1208 Dehydrogenases with different specificities (related to
short-chain alcohol dehydrogenases)
Length = 397
Score = 205 bits (522), Expect = 9e-53
Identities = 125/373 (33%), Positives = 203/373 (53%), Gaps = 21/373 (5%)
Query: 19 YLRPVLTWSPY------LAFIGAIKYWSGGPSNTWERNLHGKLYIVTGGTTQSMGTSVVL 72
Y + W+ Y ++ I A K+W+ G + TWER ++G + +VTGG++ +G VV
Sbjct: 35 YEHLITHWAQYTKAAIAVSTIAAFKFWTSGRTTTWERKMNGMVVMVTGGSS-GIGQVVVE 93
Query: 73 DMARRGAQMIVLCR-KIDEWSEEWCEQMRELTGNELIYLEQCDLSDLFEVRKFATKWLDN 131
+A GAQ+++L R + D+++ ++ +R+ T N+LIY E CDLS + VRKFATKW+D
Sbjct: 94 KLASLGAQVVILLRTEPDQFTVDYIMDLRKRTKNQLIYTEVCDLSSMLSVRKFATKWIDC 153
Query: 132 APPRRLDGIIVMSGDCEPWGLRKKKTSTDGIEIQMATNYAGVFHLLNLMKPSFKAQPPDR 191
P RRLD I++ SG P ++T+ +G+E+Q ATN+ G + LL +++P QP R
Sbjct: 154 TPIRRLDMIVLCSGVLLP-PFMDRQTTEEGVELQWATNFLGPYQLLRILRPVIYGQPGHR 212
Query: 192 DVRIIVTTCFLQAMGKCNVEDPLWLHAPF--KNSRELFSSSKLQLSLAMLHLQRLLITEA 249
+VRI+ TC +G + D + P+ K+ ++ ++KL L + Q+ +A
Sbjct: 213 EVRIVAATCSSYILGNIDFNDLDLSNHPYPRKSPWKVVGNAKLALMTYLYDFQK----KA 268
Query: 250 GNSAKDGRSGKNVTVTVVQPGLMRSPSLRRVVSNGSXXXXXXXXXXXXXPFLWLLTKSGY 309
+ + N+ + PG++R+P RRVVS G PF WLL K
Sbjct: 269 EAHERPDKMPCNLHTIMANPGVVRTPGFRRVVSFGK--VWGLFLYLLLWPFWWLLLKGTI 326
Query: 310 RGAQTIIYSITTPELEEVNRTDDEVKYIANCSIVNFARKEFYDKELQEKLYENTIKQIES 369
GAQ+ ++I +PE + + + CSIV ++RKE D E EKL + QI+
Sbjct: 327 HGAQSFFHAICSPEFASIT----QPVLVNECSIVEYSRKEITDPEFAEKLIKAADAQIDE 382
Query: 370 VEKKMAAQRNQAS 382
VEK+ ++ + S
Sbjct: 383 VEKQYKKKKIKKS 395
>7304180 [Q] KOG1208 Dehydrogenases with different specificities (related to
short-chain alcohol dehydrogenases)
Length = 327
Score = 94.4 bits (233), Expect = 3e-19
Identities = 83/306 (27%), Positives = 135/306 (43%), Gaps = 39/306 (12%)
Query: 53 GKLYIVTGGTTQSMGTSVVLDMARRGAQMIVLCRKIDEWSEEWCEQMRELTGNELIYLEQ 112
GK+ IVTGG T +G V+++ARRGA + + CR ++ E ++E TGN ++ +
Sbjct: 45 GKVAIVTGGNT-GLGKETVMELARRGATVYMACRNKEKVERARREIVKE-TGNSNVFSRE 102
Query: 113 CDLSDLFEVRKFATKWLDNAPPRRLDGIIVMSGDC--EPWGLRKKKTSTDGIEIQMATNY 170
CDLS L +RKFA + +R+ I++ + EP L K +G E+ + N+
Sbjct: 103 CDLSSLDSIRKFAENFKKE---QRVLHILINNAGVFWEPHRLTK-----EGFEMHLGVNH 154
Query: 171 AGVFHLLNLMKPSFKAQPPDRDVRIIVTTCFLQAMGKCNVEDPLWLHAPFKNSRELFSSS 230
G F L NL+ + P R ++V G+ V+D + F + + S
Sbjct: 155 IGHFLLTNLLLGVLERSAPSR---VVVVASRAHERGQIKVDDIN--SSDFYDEGVAYCQS 209
Query: 231 KLQLSLAMLHLQRLLITEAGNSAKDGRSGKNVTVTVVQPGLMRSPSLRRVVSNGSXXXXX 290
KL L L + L G VTV + PG+ + R ++
Sbjct: 210 KLANILFTRELAKRL------------EGTGVTVNALNPGIADTEIARNMI-----FFQT 252
Query: 291 XXXXXXXXPFLWLLTKSGYRGAQTIIYSITTPELEEVNRTDDEVKYIANCSIVNFARKEF 350
P LW + K+ GAQT +Y+ P+LE V+ +Y ++C++ A
Sbjct: 253 KFAQTILRPLLWAVMKTPKNGAQTTLYAALDPDLERVSG-----QYFSDCALAPVAPAAL 307
Query: 351 YDKELQ 356
D+ Q
Sbjct: 308 DDQMAQ 313
>7304178 [Q] KOG1208 Dehydrogenases with different specificities (related to
short-chain alcohol dehydrogenases)
Length = 296
Score = 91.7 bits (226), Expect = 2e-18
Identities = 87/322 (27%), Positives = 139/322 (43%), Gaps = 49/322 (15%)
Query: 42 GPSNTWERNLHGKLYIVTGGTTQSMGTSVVLDMARRGAQMIVLCRKIDEWSEEWCEQMR- 100
G T + N G++ IVTG Q +G VL++ARRGA + + CR + + CE R
Sbjct: 3 GGQFTTKTNETGRVAIVTG-CNQGIGKETVLELARRGATVYMACRDMKK-----CENARR 56
Query: 101 ---ELTGNELIYLEQCDLSDLFEVRKFATKWLDNAPPRRLDGIIVMSG--DCEPWGLRKK 155
+ T N+ I+ Q DL + +R FA + +L +I +G DC K
Sbjct: 57 EIIKATNNQNIFARQLDLCSMKSIRNFAAGF--KREQNKLHILINNAGIMDCP------K 108
Query: 156 KTSTDGIEIQMATNYAGVFHLLNLMKPSFKAQPPDRDVRIIVTTCFLQAMGKCNVEDPLW 215
+ DG E+Q+ N+ G F L L+ K+ P R ++V + G+ +D
Sbjct: 109 MLTEDGFEMQIGVNHMGHFLLTLLLLDVLKSSAPSR---VVVLSSIAHRFGRIKRDD--- 162
Query: 216 LHAPFKNSREL-FSSSKLQLSLAMLHLQRLLITEAGNSAKDGRSGKNVTVTVVQPGLMRS 274
L++ R++ + SKL L L + L SG VTV + PG++ +
Sbjct: 163 LNSEKSYDRKMAYCQSKLANVLFTRELAKRL------------SGTGVTVNALHPGVVNT 210
Query: 275 PSLRRVVSNGSXXXXXXXXXXXXXPFLWLLTKSGYRGAQTIIYSITTPELEEVNRTDDEV 334
R GS P +W+ K+ GAQT +Y+ P LE+V+
Sbjct: 211 ELFRNTPFLGSWFGKLLIA-----PIIWIFIKTARNGAQTTLYAALDPSLEKVSG----- 260
Query: 335 KYIANCSIVNFARKEFYDKELQ 356
+Y ++C + YD + Q
Sbjct: 261 RYFSDCKQKHVGSAAQYDDDAQ 282
>7304181 [Q] KOG1208 Dehydrogenases with different specificities (related to
short-chain alcohol dehydrogenases)
Length = 331
Score = 90.9 bits (224), Expect = 3e-18
Identities = 88/322 (27%), Positives = 136/322 (41%), Gaps = 47/322 (14%)
Query: 30 LAFIGAIKYWSGGPSNTWERNLHGKLYIVTGGTTQSMGTSVVLDMARRGAQMIVLCRKID 89
LAF +K G T E N GK++IVTG T +G V ++A+RG + + CR +
Sbjct: 24 LAFF--VKDLMQGGQFTKETNETGKVFIVTGANT-GIGKETVREIAKRGGTVYMACRNLK 80
Query: 90 EWSEEWCEQMREL----TGNELIYLEQCDLSDLFEVRKFATKWLDNAPPRRLDGIIVMSG 145
+ CE+ RE T N+ +Y QCDL+ +R F + R + + V+
Sbjct: 81 K-----CEEAREEIVLETKNKYVYCRQCDLASQESIRHFVAAF-----KREQEHLHVLIN 130
Query: 146 DCEPWGLRKKKTSTDGIEIQMATNYAGVFHLLNLMKPSFKAQPPDRDVRIIVTTCFLQAM 205
+ + TS DGIE+Q+ N+ G F L NL+ K P RI+ +
Sbjct: 131 NAGVMRCPRSLTS-DGIELQLGVNHMGHFLLTNLLLDLLKKSSPS---RIVNVSSLAHTR 186
Query: 206 GKCNVEDPLWLHAPFK-NSRELFSSSKLQLSLAMLHLQRLLITEAGNSAKDGRSGKNVTV 264
G+ N D L++ + + +S SKL L L + L G NVT
Sbjct: 187 GEINTGD---LNSDKSYDEGKAYSQSKLANVLFTRELAKRL------------EGTNVTA 231
Query: 265 TVVQPGLMRSPSLRRVVSNGSXXXXXXXXXXXXXPFLWLLTKSGYRGAQTIIYSITTPEL 324
+ PG++ + +R + P W K+ GAQT +Y PEL
Sbjct: 232 NALHPGVVDTEIIRHM-----GFFNNFFAGLFVKPLFWPFVKTPRNGAQTSLYVALDPEL 286
Query: 325 EEVNRTDDEVKYIANCSIVNFA 346
E+V +Y ++C + A
Sbjct: 287 EKVTG-----QYFSDCKLKEMA 303
>Hs21553325 [Q] KOG1208 Dehydrogenases with different specificities (related to
short-chain alcohol dehydrogenases)
Length = 330
Score = 85.1 bits (209), Expect = 2e-16
Identities = 84/311 (27%), Positives = 139/311 (44%), Gaps = 36/311 (11%)
Query: 54 KLYIVTGGTTQSMGTSVVLDMARRGAQMIVLCRKIDEWSEEWCEQMRELTGNELIYLEQC 113
++ IVTGGT +G S +AR G +I+ D +++ +++E T N+ + C
Sbjct: 44 RVAIVTGGT-DGIGYSTAKHLARLGMHVIIAGNN-DSKAKQVVSKIKEETLNDKVEFLYC 101
Query: 114 DLSDLFEVRKFATKWLDNAPPRRLDGIIVMSGDCEPWGLRKKKTSTDGIEIQMATNYAGV 173
DL+ + +R+F K+ P + V+ + + ++KT DG E NY G
Sbjct: 102 DLASMTSIRQFVQKFKMKKIP-----LHVLINNAGVMMVPQRKTR-DGFEEHFGLNYLGH 155
Query: 174 FHLLNLMKPSFKAQ-PPDRDVRIIVTTCFLQAMGKCNVEDPLWLHAPFKNSRELFSSSKL 232
F L NL+ + K P R++ + + + N++D L A + + ++ SKL
Sbjct: 156 FLLTNLLLDTLKESGSPGHSARVVTVSSATHYVAELNMDD-LQSSACY-SPHAAYAQSKL 213
Query: 233 QLSLAMLHLQRLLITEAGNSAKDGRSGKNVTVTVVQPGLMRSPSLRRVVSNGSXXXXXXX 292
L L HLQRLL E G +VT VV PG++ + + V
Sbjct: 214 ALVLFTYHLQRLLAAE----------GSHVTANVVDPGVVNTDLYKHVF---------WA 254
Query: 293 XXXXXXPFLWLLTKSGYRGAQTIIYSITTPELEEVNRTDDEVKYIANCSIVNFARKEFYD 352
WLL K+ GA T IY+ TPELE V +Y+ N + Y+
Sbjct: 255 TRLAKKLLGWLLFKTPDEGAWTSIYAAVTPELEGVGG-----RYLYNEKETK-SLHVTYN 308
Query: 353 KELQEKLYENT 363
++LQ++L+ +
Sbjct: 309 QKLQQQLWSKS 319
>Hs10190746 [Q] KOG1208 Dehydrogenases with different specificities (related to
short-chain alcohol dehydrogenases)
Length = 336
Score = 79.0 bits (193), Expect = 1e-14
Identities = 87/324 (26%), Positives = 137/324 (41%), Gaps = 51/324 (15%)
Query: 51 LHGKLYIVTGGTTQSMGTSVVLDMARRGAQMIVLCRKIDEWSEEWCEQMREL-------- 102
+HGK ++TG + +G + ++ R GA++I+ CR E + REL
Sbjct: 41 MHGKTVLITGANS-GLGRATAAELLRLGARVIMGCRDRARAEEAAGQLRRELRQAAECGP 99
Query: 103 ----TGNELIYLEQCDLSDLFEVRKFATKWLDNAPPRRLDGIIVMSGDCEPWGLRKKKTS 158
+G + + + DL+ L VR F + L P RLD +I +G + ++ +
Sbjct: 100 EPGVSGVGELIVRELDLASLRSVRAFCQEMLQEEP--RLDVLINNAGIFQCPYMKTE--- 154
Query: 159 TDGIEIQMATNYAGVFHLLNLMKPSFKAQPPDRDVRIIVTTCFLQAMGKCNVEDPLWLHA 218
DG E+Q N+ G F L NL+ K+ P RI+V + L G N +D L++
Sbjct: 155 -DGFEMQFGVNHLGHFLLTNLLLGLLKSSAPS---RIVVVSSKLYKYGDINFDD---LNS 207
Query: 219 PFK-NSRELFSSSKLQLSLAMLHLQRLLITEAGNSAKDGRSGKNVTVTVVQPGLMRSPSL 277
N +S SKL L L R L G NVTV V+ PG++R+
Sbjct: 208 EQSYNKSFCYSRSKLANILFTRELARRL------------EGTNVTVNVLHPGIVRT--- 252
Query: 278 RRVVSNGSXXXXXXXXXXXXXPFLWLLTKSGYRGAQTIIYSITTPELEEVNRTDDEVKYI 337
+ G W K+ GAQT IY ++PE+E V+ +Y
Sbjct: 253 ----NLGRHIHIPLLVKPLFNLVSWAFFKTPVEGAQTSIYLASSPEVEGVSG-----RYF 303
Query: 338 ANCSIVNFARKEFYDKELQEKLYE 361
+C K D+ + KL++
Sbjct: 304 GDCKEEELLPKAM-DESVARKLWD 326
>7304177 [Q] KOG1208 Dehydrogenases with different specificities (related to
short-chain alcohol dehydrogenases)
Length = 300
Score = 78.2 bits (191), Expect = 2e-14
Identities = 75/277 (27%), Positives = 121/277 (43%), Gaps = 32/277 (11%)
Query: 53 GKLYIVTGGTTQSMGTSVVLDMARRGAQMIVLCRKIDEWSEEWCEQMRELTGNELIYLEQ 112
GK++IVTG T +G VL++A+RG + + CR ++ + + +RE T N+ I+ +
Sbjct: 14 GKVFIVTGANT-GIGKETVLEIAKRGGTVYMACRDMNRCEKARQDIIRE-TNNQNIFSRE 71
Query: 113 CDLSDLFEVRKFATKWLDNAPPRRLDGIIVMSGDCEPWGLRKKKTSTDGIEIQMATNYAG 172
DLS L +RKFA + + D + V+ + + T DG E+Q+ N+ G
Sbjct: 72 LDLSSLESIRKFAAGF-----KKEQDKLHVLINNAGVMHCPRTLTK-DGFEMQLGVNHMG 125
Query: 173 VFHLLNLMKPSFKAQPPDRDVRIIVTTCFLQAMGKCNVEDPLWLHAPFKNSR-ELFSSSK 231
F L +L+ K P R V + + + G D L++ SR +S SK
Sbjct: 126 HFLLTHLLLDVLKKTAPSRIVNV---SSLVHTQGFIKTAD---LNSEKSYSRIGAYSQSK 179
Query: 232 LQLSLAMLHLQRLLITEAGNSAKDGRSGKNVTVTVVQPGLMRSPSLRRVVSNGSXXXXXX 291
L L L + L G VT + PG + + +S
Sbjct: 180 LANVLFTRELAKRL------------EGTGVTTNSLHPGAVDTE-----LSRNWKFLKHP 222
Query: 292 XXXXXXXPFLWLLTKSGYRGAQTIIYSITTPELEEVN 328
P LW+L K+ GAQT +Y+ P L++V+
Sbjct: 223 FAQLLLKPLLWVLFKTPRNGAQTTLYAALDPALKDVS 259
>CE20634 [Q] KOG1208 Dehydrogenases with different specificities (related to
short-chain alcohol dehydrogenases)
Length = 398
Score = 76.6 bits (187), Expect = 6e-14
Identities = 90/319 (28%), Positives = 141/319 (43%), Gaps = 43/319 (13%)
Query: 50 NLHGKLYIVTGGTTQSMGTSVVLDMARRGAQMIVLCRKIDEWSEEWCEQMRELTGNELIY 109
+L GK Y +TG TT +GT +GA ++++ R SE + + T + I
Sbjct: 103 DLSGKTYAITG-TTSGVGTETARAFILKGAHIVMINRNYAA-SETLKQSLLCETPDARID 160
Query: 110 LEQCDLSDLFEVRKFATKWLDNAPPRRLDGIIVMSGDCEPWGLRKKKTSTDGIEIQMATN 169
+ QCDLS L V+K A ++L P L G+I+ +G RK+KT+ D E N
Sbjct: 161 IVQCDLSSLASVKKTAEEYLTKKWP--LHGLILNAGVLG----RKEKTTADRFEAHFGIN 214
Query: 170 YAGVFHLLNLMKPSFKAQPPDRDVRIIVT-TCFLQAMGKCNVEDPLWLHAPFKNSRE--- 225
+ F L+ + P ++ P R V + T + F +E+ L P KN+ E
Sbjct: 215 HLAHFLLIKELLPVLRSSAPSRIVILSSTLSKFTSINPDSKIEEKLGTLCP-KNATEWYY 273
Query: 226 -LFSSSKLQLSLAMLHLQRLLITEAGNSAKDGRSGKNVTVTVVQPGLMRSPSLRRVVSNG 284
L++ SK+ L L R + ++G ++V V PG +L R V
Sbjct: 274 RLYAKSKMCNMLIAFKLHR-------DEFENG-----ISVYSVHPGSAVRTNLHRDVPFW 321
Query: 285 SXXXXXXXXXXXXXPFLWLLTKSGYRGAQTIIYSITTPELEEVNRTDDEVKYIANC--SI 342
S PF TK+ +GA T +Y PE++E++ +Y +C
Sbjct: 322 S------IFNFLSIPF----TKNASQGAATSLYCAVHPEVQELSG-----RYWESCWDDE 366
Query: 343 VNFARKEFYDKELQEKLYE 361
+N K D+ELQE L+E
Sbjct: 367 LNLDEKVARDEELQEALWE 385
>7300387 [Q] KOG1208 Dehydrogenases with different specificities (related to
short-chain alcohol dehydrogenases)
Length = 317
Score = 74.3 bits (181), Expect = 3e-13
Identities = 85/332 (25%), Positives = 143/332 (42%), Gaps = 61/332 (18%)
Query: 48 ERNLHGKLYIVTGGTTQSMGTSVVLDMARRGAQMIVLCRKIDEWSEEWCEQMRELTGNEL 107
E + GK I+TG + +G D+A RGA++I+ CR ++ + E ++E T N
Sbjct: 28 ETKMEGKTVIITGANS-GIGKETAKDLAGRGARIIMACRNLETANAVKDEIVKE-TKNNK 85
Query: 108 IYLEQCDLSDLFEVRKFATKWLDNAPPRRLDGIIVMSGDCEPWGLRKKKTSTDGIEIQMA 167
I +++ DL VR+FA + P ++D +I +G + + +TS DG+E+ MA
Sbjct: 86 ILVKKLDLGSQKSVREFAADIVKTEP--KIDVLIHNAGMALAF---RGQTSEDGVELTMA 140
Query: 168 TNYAGVFHLLNLMKPSFKAQPPDRDVRIIVTTCFLQAMGKCNVE--DPLWLHAPFKNSRE 225
TN+ G F L +L+ K P RI++ L + N+ +P+ F +
Sbjct: 141 TNHYGPFLLTHLLIDVLKKSAP---ARIVIVASELYRLSSVNLAKLNPI---GTFPAAYL 194
Query: 226 LFSSSKLQLSLAMLHLQRLLITEAGNSAKDGRSGKNVTVTVVQPGLMRSPSLRRVVSNGS 285
+ S + A +RL G VTV + PG++ S R V
Sbjct: 195 YYVSKFANIYFARELAKRL-------------EGTKVTVNFLHPGMIDSGIWRNV----- 236
Query: 286 XXXXXXXXXXXXXPF-----LWLLTKSGYR----GAQTIIYSITTPELEEVNRTDDEVKY 336
PF + +TK ++ GAQT IY T+ E+ V+ KY
Sbjct: 237 -------------PFPLNLPMMAITKGFFKTTKAGAQTTIYLATSNEVANVSG-----KY 278
Query: 337 IANCSIVNFARKEFYDKELQEKLYENTIKQIE 368
+C D+E K++E ++K ++
Sbjct: 279 FMDCKEATL-NAAALDEEKGLKIWEESVKIVK 309
>Hs19923931 [Q] KOG1208 Dehydrogenases with different specificities (related to
short-chain alcohol dehydrogenases)
Length = 260
Score = 73.2 bits (178), Expect = 7e-13
Identities = 68/241 (28%), Positives = 97/241 (40%), Gaps = 31/241 (12%)
Query: 90 EWSEEWCEQMRELTGNELIYLEQCDLSDLFEVRKFATKWLDNAPPRRLDGIIVMSG--DC 147
E E + +R T N + DL+ L +R+FA K ++ R+D +I +G C
Sbjct: 2 EKCEAAAKDIRGETLNHHVNARHLDLASLKSIREFAAKIIEEE--ERVDILINNAGVMRC 59
Query: 148 EPWGLRKKKTSTDGIEIQMATNYAGVFHLLNLMKPSFKAQPPDRDVRIIVTTCFLQAMGK 207
W T+ DG E+Q N+ G F L NL+ KA P RII + G
Sbjct: 60 PHW------TTEDGFEMQFGVNHLGHFLLTNLLLDKLKASAPS---RIINLSSLAHVAGH 110
Query: 208 CNVEDPLWLHAPFKNSRELFSSSKLQLSLAMLHLQRLLITEAGNSAKDGRSGKNVTVTVV 267
+ +D W + N++ + SKL + L L R L G VTV +
Sbjct: 111 IDFDDLNWQTRKY-NTKAAYCQSKLAIVLFTKELSRRL------------QGSGVTVNAL 157
Query: 268 QPGLMRSPSLRRVVSNGSXXXXXXXXXXXXXPFLWLLTKSGYRGAQTIIYSITTPELEEV 327
PG+ R+ R +GS P WLL KS AQ Y EL +V
Sbjct: 158 HPGVARTELGRHTGIHGS-----TFSSTTLGPIFWLLVKSPELAAQPSTYLAVAEELADV 212
Query: 328 N 328
+
Sbjct: 213 S 213
>CE27908 [Q] KOG1208 Dehydrogenases with different specificities (related to
short-chain alcohol dehydrogenases)
Length = 319
Score = 72.0 bits (175), Expect = 1e-12
Identities = 85/327 (25%), Positives = 138/327 (41%), Gaps = 47/327 (14%)
Query: 50 NLHGKLYIVTGGTTQSMGTSVVLDMARRGAQMIVLCRKIDEWSEEWCEQMRELTGNELIY 109
+L GK + +TG TT +G + +GA ++++ R SE + + T N I
Sbjct: 25 DLSGKTFAITG-TTSGIGVETAKALILKGAHVVMINRNYTA-SEASKKSLLIETPNAQID 82
Query: 110 LEQCDLSDLFEVRKFATKWLDNAPPRRLDGIIVMSGDCEPWGLRKKKTSTDGIEIQMATN 169
+ QCDL+ L V+K A ++L+ P L G+I+ +G P +KT++DG E N
Sbjct: 83 IVQCDLNSLSSVKKAADEYLEQKWP--LHGLILNAGVFGP----SEKTTSDGFEAHFGIN 136
Query: 170 YAGVFHLLNLMKPSFKAQPPDRDVRIIVTTCFLQ----AMGKCNVEDPLWLHAPFKNSR- 224
+ F L+ + P + P RI++ T L + + L P + ++
Sbjct: 137 HLAHFILIKELLPVLRESAPS---RIVIVTSMLSKHTCVKPDSRIVEKLDTLCPKEATQW 193
Query: 225 --ELFSSSKLQLSLAMLHLQRLLITEAGNSAKDGRSGKNVTVTVVQPGLMRSPSLRRVVS 282
L++ SK+ L L R ++V V PG L R
Sbjct: 194 YFRLYAKSKMCNILTAFKLHR------------DEFKNRISVYAVHPGSGVRTDLHRDFG 241
Query: 283 NGSXXXXXXXXXXXXXPFLWLLTKSGYRGAQTIIYSITTPELEEVNRTDDEVKYIANC-- 340
S PF TK+ +GA T +Y PE++E++ KY +C
Sbjct: 242 LWS------IADFLSIPF----TKNASQGAATSLYCAVHPEVKELSG-----KYWESCWD 286
Query: 341 SIVNFARKEFYDKELQEKLYENTIKQI 367
N +K D+ELQE L+E++ K I
Sbjct: 287 DEKNLDKKVSRDEELQEALWEHSEKLI 313
>7304176 [Q] KOG1208 Dehydrogenases with different specificities (related to
short-chain alcohol dehydrogenases)
Length = 280
Score = 71.6 bits (174), Expect = 2e-12
Identities = 73/277 (26%), Positives = 118/277 (42%), Gaps = 53/277 (19%)
Query: 53 GKLYIVTGGTTQSMGTSVVLDMARRGAQMIVLCRKIDEWSEEWCEQMRELTGNELIYLEQ 112
GK++IVTG T +G L++ARRG + + CR ++ + + ++E T N+ I+ +
Sbjct: 14 GKVFIVTGANT-GIGKETALEIARRGGTVYLACRDMNRCEKARKDIIKE-TNNQNIFSRE 71
Query: 113 CDLSDLFEVRKFATKWLDNAPPRRLDGIIVMSGDCEPWGLRKKKTST-DGIEIQMATNYA 171
DLS L +RKF + P +L +I +G +R KT T DG E+Q+ N+
Sbjct: 72 LDLSSLDSIRKFVDGFKKEQP--KLHVLINNAGV-----MRCPKTLTKDGYELQLGVNHI 124
Query: 172 GVFHLLNLMKPSFKAQPPDRDVRIIVTTCFLQAMGKCNVEDPLWLHAPFKNSRELFSSSK 231
G F L NL+ KA + + + ++ L +S SK
Sbjct: 125 GHFLLTNLLLDVLKATDLNSEK---------------SYDEGL-----------AYSQSK 158
Query: 232 LQLSLAMLHLQRLLITEAGNSAKDGRSGKNVTVTVVQPGLMRSPSLRRVVSNGSXXXXXX 291
L L L + L G VTV + PG++ + ++
Sbjct: 159 LANVLFTRELAKRL------------EGSGVTVNALHPGVVDTE-----LARNWAFFQTN 201
Query: 292 XXXXXXXPFLWLLTKSGYRGAQTIIYSITTPELEEVN 328
P +W L K+ GAQT IY+ PEL+ ++
Sbjct: 202 LVKFFLKPMIWPLLKTPKSGAQTSIYAALDPELKNIS 238
>CE16253 [Q] KOG1208 Dehydrogenases with different specificities (related to
short-chain alcohol dehydrogenases)
Length = 379
Score = 70.1 bits (170), Expect = 6e-12
Identities = 83/331 (25%), Positives = 146/331 (44%), Gaps = 46/331 (13%)
Query: 50 NLHGKLYIVTGGTTQSMGTSVVLDMARRGAQMIVLCRKIDEWSEEWCEQMRELTGNELIY 109
++ GK + +TG TT +G + +A GA ++++ R + E SE +++ E + +
Sbjct: 82 DVSGKTFAITG-TTSGIGINTAEVLALAGAHVVLMNRNLHE-SENQKKRILEKKPSAKVD 139
Query: 110 LEQCDLSDLFEVRKFATKWLDNAPPRRLDGIIVMSGDCEPWGLRKKKTSTDGIEIQMATN 169
+ CDLSDL VRK +L P + G+I+ +G P + K DG E N
Sbjct: 140 IIFCDLSDLKTVRKAGEDYLAKNWP--IHGLILNAGVFRPAAAKTK----DGFESHYGVN 193
Query: 170 YAGVFHLLNLMKPSFKAQPPDRDVRIIVTTC----FLQAMGKCNVEDPLWLHAPFKNSRE 225
F LL ++ P + P R V + T F ++MG L ++ +
Sbjct: 194 VVAHFTLLRILLPVVRRSAPSRVVFLSSTLSSKHGFKKSMGISEKMSILQGEDSSASTLQ 253
Query: 226 LFSSSKLQLSLAMLHLQRLLITEAGNSAKDGRSGKNVTV-TVVQPGLMRSPSLRRVVSNG 284
++ +SK+ L L R + K+G S +V + V+ + R+ L + +
Sbjct: 254 MYGASKMADMLIAFKLHR-------DEYKNGISTYSVHPGSGVRTDIFRNSLLGKFIG-- 304
Query: 285 SXXXXXXXXXXXXXPFLWLLTKSGYRGAQTIIYSITTPELEEVNRTDDEVKYIANC-SIV 343
PF TK+ +GA T +Y T PE+E+++ KY +C
Sbjct: 305 ----------FVTTPF----TKNASQGAATTVYCATHPEVEKISG-----KYWESCWDND 345
Query: 344 NFARKEFYDKELQEKLYENTIKQIESVEKKM 374
+K D+ELQE L+ K++E ++ ++
Sbjct: 346 KIDKKTARDEELQEALW----KKLEQIDDRI 372
>7290709 [Q] KOG1208 Dehydrogenases with different specificities (related to
short-chain alcohol dehydrogenases)
Length = 406
Score = 70.1 bits (170), Expect = 6e-12
Identities = 72/249 (28%), Positives = 107/249 (42%), Gaps = 32/249 (12%)
Query: 30 LAFIGAIKYWSGGPSNTWERNLHGKLYIVTGGTTQSMGTSVVLDMARRGAQMIVLCRKID 89
L F+ ++ GP+ + GK+ IVTG T +G VL++A+RGA++ + CR
Sbjct: 51 LLFMWLLRKCIQGPAYRKANRIDGKVVIVTGCNT-GIGKETVLELAKRGARVYMACRDPG 109
Query: 90 EWSEEWCEQMR----ELTGNELIYLEQCDLSDLFEVRKFATKWLDNAPPRRLDGIIVMSG 145
CE R + + N+ ++ DL L VR F ++ A RLD +I +G
Sbjct: 110 R-----CEAARLDIMDRSRNQQLFNRTLDLGSLQSVRNFVERF--KAEESRLDILINNAG 162
Query: 146 DCEPWGLRKKKTSTDGIEIQMATNYAGVFHLLNLMKPSFKAQPPDRDVRIIVTTCFLQAM 205
+ + DG E Q N+ G F L NL+ K P RI+V +
Sbjct: 163 VM----ACPRTLTADGFEQQFGVNHLGHFLLTNLLLDRLKHSSPS---RIVVVSSAAHLF 215
Query: 206 GKCNVEDPLWLHAPFKNSRELFSSSKLQLSLAMLHLQRLLITEAGNSAKDGRSGKNVTVT 265
G+ N ED L + +S SKL L L L +L KD VTV
Sbjct: 216 GRINRED-LMSEKNYSKFFGAYSQSKLANILFTLKLSTIL--------KD----TGVTVN 262
Query: 266 VVQPGLMRS 274
PG++R+
Sbjct: 263 CCHPGVVRT 271
>Hs20070272 [Q] KOG1208 Dehydrogenases with different specificities (related to
short-chain alcohol dehydrogenases)
Length = 318
Score = 68.9 bits (167), Expect = 1e-11
Identities = 79/312 (25%), Positives = 131/312 (41%), Gaps = 45/312 (14%)
Query: 18 PYLRPVLTWSPYLAFIGAIKYWSGGPSNTWERNLHGKLYIVTGGTTQSMGTSVVLDMARR 77
P L +L + Y+A K S G + + L GK+ +VTG T +G ++A+R
Sbjct: 7 PLLLLLLPFLLYMAAPQIRKMLSSGVCTSTVQ-LPGKVVVVTGANT-GIGKETAKELAQR 64
Query: 78 GAQMIVLCRKIDEWSEEWCEQMRELTGNELIYLEQCDLSDLFEVRKFATKWLDNAPPRRL 137
GA++ + CR +++ E ++++ TGN+ + + + DLSD +R FA +L A + L
Sbjct: 65 GARVYLACRDVEK-GELVAKEIQTTTGNQQVLVRKLDLSDTKSIRAFAKGFL--AEEKHL 121
Query: 138 DGIIVMSGDCEPWGLRKKKTSTDGIEIQMATNYAGVFHLLNLMKPSFKAQPPDRDVRIIV 197
+I +G + + DG E+ + N+ G F L +L+ K P R V +
Sbjct: 122 HVLINNAGVM----MCPYSKTADGFEMHIGVNHLGHFLLTHLLLEKLKESAPSRIVNVSS 177
Query: 198 TTCFLQAMGKCNVEDPLWLHAPFKNSRELFSSSKLQLSLAMLHLQRLLITEAGNSAKDGR 257
L + N++ F N+ + SKL L L R L
Sbjct: 178 LAHHLGRIHFHNLQG-----EKFYNAGLAYCHSKLANILFTQELARRL------------ 220
Query: 258 SGKNVTVTVVQPGLMRSPSLRRVVSNGSXXXXXXXXXXXXXPFLWLL----TKSGYRGAQ 313
G VT V PG ++S +R ++W L K+ +GAQ
Sbjct: 221 KGSGVTTYSVHPGTVQSELVRH---------------SSFMRWMWWLFSFFIKTPQQGAQ 265
Query: 314 TIIYSITTPELE 325
T ++ T LE
Sbjct: 266 TSLHCALTEGLE 277
>At4g09750 [Q] KOG1208 Dehydrogenases with different specificities (related to
short-chain alcohol dehydrogenases)
Length = 322
Score = 68.6 bits (166), Expect = 2e-11
Identities = 43/143 (30%), Positives = 74/143 (51%), Gaps = 8/143 (5%)
Query: 51 LHGKLYIVTGGTTQSMGTSVVLDMARRGAQMIVLCRKIDEWSEEWCEQMRELTGNELIYL 110
+ GK +VTG + +G + +A RGA + ++CR E +E +++ TGN+ +YL
Sbjct: 41 IEGKNCVVTGANS-GIGFAAAEGLASRGATVYMVCRN-KERGQEALSKIQTSTGNQNVYL 98
Query: 111 EQCDLSDLFEVRKFATKWLDNAPPRRLDGIIVMSGDCEPWGLRKKKTSTDGIEIQMATNY 170
E CDLS + E++ FA+ + P + ++ +G E K+ T+ +G E+ A N
Sbjct: 99 EVCDLSSVNEIKSFASSFASKDVPVHV--LVNNAGLLE----NKRTTTPEGFELSFAVNV 152
Query: 171 AGVFHLLNLMKPSFKAQPPDRDV 193
G + + LM P + PD V
Sbjct: 153 LGTYTMTELMLPLLEKATPDAKV 175
>At2g37540 [Q] KOG1208 Dehydrogenases with different specificities (related to
short-chain alcohol dehydrogenases)
Length = 321
Score = 68.2 bits (165), Expect = 2e-11
Identities = 85/324 (26%), Positives = 134/324 (41%), Gaps = 47/324 (14%)
Query: 57 IVTGGTTQSMGTSVVLDMARRGAQMIVLCRKIDEWSEEWCEQMRELTGNELIYLEQCDLS 116
I+TGGT+ +G +A RGA +I+ R + + E E + ++ N + Q D+S
Sbjct: 37 IITGGTS-GIGLEAARVLAMRGAHVIIAARN-PKAANESKEMILQMNPNARVDYLQIDVS 94
Query: 117 DLFEVRKFATKWLDNAPPRRLDGIIVMSGDCEPWGLRKKKTSTDGIEIQMATNYAGVFHL 176
+ VR F ++L P L+ +I +G K + DGIE Q ATN+ G F L
Sbjct: 95 SIKSVRSFVDQFLALNVP--LNILINNAGVM----FCPFKLTEDGIESQFATNHIGHFLL 148
Query: 177 LNLMKPSFKAQPPDRDVR--------IIVTTCFLQAMGKCNVEDPLWLHAPFKNSRELFS 228
NL+ K+ + V+ I T + + + + DP + R +
Sbjct: 149 TNLLLDKMKSTARESGVQGRIVNLSSIAHTYTYSEGIKFQGINDPAGY-----SERRAYG 203
Query: 229 SSKLQLSLAMLHLQRLLITEAGNSAKDGRSGKNVTVTVVQPGLMRSPSLRRVVSNGSXXX 288
SKL L L R L E G N+T+ V PGL+ + R
Sbjct: 204 QSKLSNLLHSNALSRRLQEE----------GVNITINSVHPGLVTTNLFR---------- 243
Query: 289 XXXXXXXXXXPFLWLLTKSGYRGAQTIIYSITTPELEEVNRTDDEVKYIANCSIVNFARK 348
+L K+ +GA T Y P+LE V KY +C+IV K
Sbjct: 244 YSGFSMKVFRAMTFLFWKNIPQGAATTCYVALHPDLEGVTG-----KYFGDCNIV-APSK 297
Query: 349 EFYDKELQEKLYENTIKQIESVEK 372
+ L +KL++ ++ I+S+ K
Sbjct: 298 FATNNSLADKLWDFSVFLIDSISK 321
>Hs18582884 [Q] KOG1208 Dehydrogenases with different specificities (related to
short-chain alcohol dehydrogenases)
Length = 316
Score = 65.5 bits (158), Expect = 1e-10
Identities = 78/309 (25%), Positives = 126/309 (40%), Gaps = 52/309 (16%)
Query: 37 KYWSGGPSNTWERNLHGKLYIVTGGTTQSMGTSVVLDMARRGAQMIVLCRKIDEWSEEWC 96
K+++GG T L GK+ ++TG T +G ++A RGA++ + CR + + E
Sbjct: 24 KFFAGGVCRT-NVQLPGKVVVITGANT-GIGKETARELASRGARVYIACRDVLK-GESAA 80
Query: 97 EQMRELTGNELIYLEQCDLSDLFEVRKFATKWLDNAPPRRLDGIIVMSGDCEPWGLRKKK 156
++R T N + + + DLSD +R FA +L A ++L +I +G +
Sbjct: 81 SEIRVDTKNSQVLVRKLDLSDTKSIRAFAEGFL--AEEKQLHILINNAGVM----MCPYS 134
Query: 157 TSTDGIEIQMATNYAGVFHLLNLMKPSFKAQPPDRDVRIIVTTCFLQAMGKCNVEDPLWL 216
+ DG E + N+ G F L L+ K P R++ + +GK D L
Sbjct: 135 KTADGFETHLGVNHLGHFLLTYLLLERLKVSAP---ARVVNVSSVAHHIGKIPFHD---L 188
Query: 217 HAPFKNSREL-FSSSKLQLSLAMLHLQRLLITEAGNSAKDGRSGKNVTVTVVQPGLMRSP 275
+ + SR + SKL L L + L G VT V PG++RS
Sbjct: 189 QSEKRYSRGFAYCHSKLANVLFTRELAKRL------------QGTGVTTYAVHPGVVRSE 236
Query: 276 SLRRVVSNGSXXXXXXXXXXXXXPFLWLL----TKSGYRGAQTIIYSITTPELEEVNRTD 331
+R LW L K+ GAQT ++ LE ++
Sbjct: 237 LVRH---------------SSLLCLLWRLFSPFVKTAREGAQTSLHCALAEGLEPLSG-- 279
Query: 332 DEVKYIANC 340
KY ++C
Sbjct: 280 ---KYFSDC 285
>Hs21389583 [Q] KOG1208 Dehydrogenases with different specificities (related to
short-chain alcohol dehydrogenases)
Length = 327
Score = 62.0 bits (149), Expect = 2e-09
Identities = 65/271 (23%), Positives = 108/271 (38%), Gaps = 37/271 (13%)
Query: 72 LDMARRGAQMIVLCRKIDEWSEEWCEQMRELTGNELIYLEQCDLSDLFEVRKFATKWLDN 131
L++ARRGA++++ CR E E +R+ +GN + DL+ L VR FAT +L +
Sbjct: 4 LELARRGARVVLACRS-QERGEAAAFDLRQESGNNEVIFMALDLASLASVRAFATAFLSS 62
Query: 132 APPRRLDGIIVMSGDCEPWGLRKKKTSTDGIEIQMATNYAGVFHLLNLMKPSFKAQPPDR 191
P RLD +I + G+ + + + + N+ G F L +L+ P KA P
Sbjct: 63 EP--RLDILIHNA------GISSCGRTREAFNLLLRVNHIGPFLLTHLLLPCLKACAPS- 113
Query: 192 DVRIIVTTCFLQAMGKCNVEDPLWLHAPFKNSRELFSSSKLQLSLAMLHLQRLLITEAGN 251
R++V G+ + + ++ ++ +KL L L L
Sbjct: 114 --RVVVVASAAHCRGRLDFKRLDRPVVGWRQELRAYADTKLANVLFARELANQL------ 165
Query: 252 SAKDGRSGKNVTVTVVQPGLMRSPSLRRVVSNGSXXXXXXXXXXXXXPFLWLLTKSGYRG 311
VT PG + S R V P WL+ ++ G
Sbjct: 166 ------EATGVTCYAAHPGPVNSELFLRHVPG--------WLRPLLRPLAWLVLRAPRGG 211
Query: 312 AQTIIYSITTPELEEVNRTDDEVKYIANCSI 342
AQT +Y +E ++ +Y ANC +
Sbjct: 212 AQTPLYCALQEGIEPLSG-----RYFANCHV 237
>CE08181 [Q] KOG1208 Dehydrogenases with different specificities (related to
short-chain alcohol dehydrogenases)
Length = 333
Score = 60.5 bits (145), Expect = 4e-09
Identities = 74/307 (24%), Positives = 126/307 (40%), Gaps = 33/307 (10%)
Query: 37 KYWSGGPSNTWERNLHGKLYIVTGGTTQSMGTSVVLDMARRGAQMIVLCRKIDEWSEEWC 96
+Y+ GG N ER L V G+ +G V ++ R A + +LCR ++ +E
Sbjct: 31 RYFKGGQFN--ERVSAKGLVAVVTGSNCGIGFETVRELNLRKADVYMLCRSEEKANEAKR 88
Query: 97 EQMRELTGNELIYLEQCDLSDLFEVRKFATKWLDNAPPRRLDGIIVMSGDCEPWGLRKKK 156
+R+ ++ +CDL+D VR+ A + L++ D I ++ + K +
Sbjct: 89 MLVRQGCDATRLHFIECDLTDFESVRRAAKETLEST-----DTIDILINNAGIMFQSKHE 143
Query: 157 TSTDGIEIQMATNYAGVFHLLNLMKPSFKAQPPDRDVRIIVTTCF-LQAMGKCNVEDPLW 215
+ DG E +N+ G F L L P+ K R + + + + V+D
Sbjct: 144 QTKDGHEKTWQSNHLGPFLLTELFLPAVKKSSYARIINVSSRIHLKSEKINLATVDD--- 200
Query: 216 LHAPFKNSRELFSSSKLQLSLAMLHLQRLLITEAGNSAKDGRSGKNVTVTVVQPGLMRSP 275
K S + S + Q LA + R L E KDG ++VTV + PG++ +
Sbjct: 201 -----KKSFGMMKSYR-QSKLANVMHARALTKEL---RKDG--AEHVTVNSLHPGVVNTE 249
Query: 276 SLRRVVSNGSXXXXXXXXXXXXXPFLWLLTKSGYRGAQTIIYSITTPELEEVNRTDDEVK 335
R + N F W L K+ GAQT I+ ++ ++ K
Sbjct: 250 LARNTILN------TPGIKQITAVFRWFLMKTSRDGAQTSIFLALGKKIGGISG-----K 298
Query: 336 YIANCSI 342
Y A+C +
Sbjct: 299 YFADCKL 305
>CE01219 [Q] KOG1208 Dehydrogenases with different specificities (related to
short-chain alcohol dehydrogenases)
Length = 329
Score = 59.7 bits (143), Expect = 8e-09
Identities = 82/343 (23%), Positives = 152/343 (43%), Gaps = 56/343 (16%)
Query: 50 NLHGKLYIVTGGTTQSMGTSVVLDMARRGAQMIVLCRKIDEWSEEWCEQMRELTGNELIY 109
NL GK ++VTG TT +G ++ GA +++L R ++E SE+ +++ E + I
Sbjct: 25 NLAGKTFVVTG-TTSGIGIETARSLSLNGAHVVMLNRNLEE-SEKLKKKIVEEMNDAEID 82
Query: 110 LEQCDLSDLFEVRKFATKWLDNAPPRRLDGIIVMSGDCEPWGLRKKKTSTDGIEIQMATN 169
+ +CDL+ L V+K A ++ + +I+ +G +G K T+ DG+E A N
Sbjct: 83 IIECDLNSLHSVKKAAEVYISKK--WSIHCLILNAG---VFGTASK-TTVDGLESHFAIN 136
Query: 170 YAGVFHLLNLMKPSFKAQPPDRDVRI---IVTTCFLQAMGKCNVEDPLWLHAPFKNSR-- 224
+ F L+ + P + P R V + + TC + + ++E+ L + P +S
Sbjct: 137 HLSHFLLIQELLPIVRQSIPSRIVLVSSSVHATCGVSP--EMSIEEKLKILCPESSSDAS 194
Query: 225 --ELFSSSKLQLSLAMLHLQRLLITEAGNSAKDGRSGKNVTVTVVQPGLMRSPSLRRVVS 282
L+S SK+ L L R G S G V ++ + + S+ ++S
Sbjct: 195 WFRLYSRSKMCNMLVAFKLHRDEY-HNGISTYSVHPGNGVRTSIFRDSWL--VSIASILS 251
Query: 283 NGSXXXXXXXXXXXXXPFLWLLTKSGYRGAQTIIYSITTPELEEV------NRTDDEVKY 336
PF TK+ +GA T +Y PE+ V + DDE
Sbjct: 252 ---------------TPF----TKNISQGASTTVYCAGHPEVANVSGKYWDSNWDDE--- 289
Query: 337 IANCSIVNFARKEFYDKELQEKLYENTIKQIESV--EKKMAAQ 377
+ D++LQ+ L++++ K ++++ ++K + Q
Sbjct: 290 ------KGLYEEVARDEQLQDALWKHSDKILDNMLNDRKKSCQ 326
>At4g24050 [Q] KOG1208 Dehydrogenases with different specificities (related to
short-chain alcohol dehydrogenases)
Length = 332
Score = 54.7 bits (130), Expect = 2e-07
Identities = 74/290 (25%), Positives = 112/290 (38%), Gaps = 38/290 (13%)
Query: 58 VTGGTTQSMGTSVVLDMARRGAQMIVLCRKIDEWSEEWCEQMRELTGNELIYLEQCDLSD 117
V G T +G +A+RGA++I R + E + E E++ ++ DLS
Sbjct: 38 VITGATSGIGAETARVLAKRGARLIFPARNVKAAEEAKERIVSEFPETEIVVMK-LDLSS 96
Query: 118 LFEVRKFATKWLDNAPPRRLDGIIVMSGDCEPWGLRKKKTSTDGIEIQMATNYAGVFHLL 177
+ VR F + P L +I +G + S DGIE+ ATNY G F L
Sbjct: 97 IASVRNFVADFESLDLPLNL--LINNAGKLA----HEHAISEDGIEMTFATNYLGHFLLT 150
Query: 178 NLM--KPSFKAQPPDRDVRIIVTTCFLQAMGKCNVEDPLWLHAPFKNSRELFSSSKLQL- 234
NL+ K A+ RI+ T + W L S K Q
Sbjct: 151 NLLLNKMIQTAEETGVQGRIVNVTSGIHG----------WFSGDLIEYLRLISQPKCQFD 200
Query: 235 ---SLAMLHLQRLLITEAGNSAKDGRSGKNVTVTVVQPGLMRSPSLRRVVSNGSXXXXXX 291
+ A+ L +L T+ S++ + G NVTV V PG++R+ R+ +
Sbjct: 201 ATRAYALSKLANVLHTKE-LSSRLQKIGANVTVNCVHPGVVRT----RLTRDREGLLTDL 255
Query: 292 XXXXXXXPFLWLLTKSGYRGAQTIIYSITTPELEEVNRTDDEVKYIANCS 341
L K+ + A T Y T P L V+ KY +C+
Sbjct: 256 VFFLASK-----LVKTVPQAAATTCYVATNPRLVNVSG-----KYFTDCN 295
>At1g64590 [Q] KOG1208 Dehydrogenases with different specificities (related to
short-chain alcohol dehydrogenases)
Length = 334
Score = 53.9 bits (128), Expect = 4e-07
Identities = 80/319 (25%), Positives = 125/319 (39%), Gaps = 51/319 (15%)
Query: 40 SGGPSN----------TWERNLHGKLYIVTGGTTQSMGTSVVLDMARRGAQMIVLCRKID 89
SGGPS T +L I+TG T+ +G +A+RGA++++ R +
Sbjct: 11 SGGPSGFGSRSTADHVTCNSDLRSLTAIITGATS-GIGAETARVLAKRGARLVLPARSVK 69
Query: 90 EWSEEWCEQMRELTGNELIYLEQCDLSDLFEVRKFATKWLDNAPPRRLDGIIVMSGDCEP 149
E + E E+I + DLS L VR+F + P L+ +I +G
Sbjct: 70 TAEETKARILSEFPDAEIIVMH-LDLSSLTSVRRFVDDFESLNLP--LNILINNAGKYA- 125
Query: 150 WGLRKKKTSTDGIEIQMATNYAGVFHLLNLMKPSFKAQPPDRDV--RIIVTTCFLQAMGK 207
K S DG+E+ ATNY G F L L+ V RI+ T + +
Sbjct: 126 ---HKHALSEDGVEMTFATNYLGHFLLTKLLLKKMIETAAQTGVQGRIVNVTSVVHSWFS 182
Query: 208 CNVEDPLWLHAPFKNSR-----ELFSSSKLQLSLAMLHLQRLLITEAGNSAKDGRSGKNV 262
++ +L +N+R ++ SKL L + L RLL + NV
Sbjct: 183 GDMLQ--YLADISRNNRNYDATRAYALSKLANVLHTVELSRLL----------HKMDANV 230
Query: 263 TVTVVQPGLMRSPSLRRVVSNGSXXXXXXXXXXXXXPFLWLLTKSGYRGAQTIIYSITTP 322
T V PG++++ R+ + L KS + A T Y T+P
Sbjct: 231 TANCVHPGIVKT----RLTRDREGVVTDLVFFLTSK-----LLKSVPQAAATTCYVATSP 281
Query: 323 ELEEVNRTDDEVKYIANCS 341
L V KY ++C+
Sbjct: 282 RLRNVCG-----KYFSDCN 295
>7300378 [Q] KOG1208 Dehydrogenases with different specificities (related to
short-chain alcohol dehydrogenases)
Length = 131
Score = 52.0 bits (123), Expect = 2e-06
Identities = 31/74 (41%), Positives = 41/74 (54%), Gaps = 6/74 (8%)
Query: 299 PFLWLLTKSGYRGAQTIIYSITTPELEEVNRTDDEVKYIANCSIVNFARKEFYDKELQEK 358
P++WL K+ Y GAQ I T P+L+EV +Y +C I + DKEL +K
Sbjct: 12 PWMWLFMKNAYEGAQCAIRLATDPQLKEVTG-----EYFNDCEIA-ASSVTGQDKELAKK 65
Query: 359 LYENTIKQIESVEK 372
LY TIK +ESV K
Sbjct: 66 LYMQTIKTLESVTK 79
>At4g11410 [Q] KOG1208 Dehydrogenases with different specificities (related to
short-chain alcohol dehydrogenases)
Length = 317
Score = 51.6 bits (122), Expect = 2e-06
Identities = 80/350 (22%), Positives = 144/350 (40%), Gaps = 66/350 (18%)
Query: 38 YWSGGPS----NTWERNLHG----KLYIVTGGTTQSMGTSVVLDMARRGAQMIVLCRKID 89
+W G +T E HG L + G + +G +A RG +++ R D
Sbjct: 5 WWKGASGFSARSTAEEVTHGIDGTGLTAIVTGASSGIGEETTRVLALRGVHVVMAVRNTD 64
Query: 90 EWSEEWCEQMRELTGNELIYLEQCDLSDLFEVRKFATKWLDNAPPRRLDGIIVMSGDCE- 148
++ + ++E+ ++ ++ DLS + VR FA+++ P L +I +G
Sbjct: 65 SGNQVRDKILKEIPQAKIDVMK-LDLSSMASVRSFASEYQSLDLPLNL--LINNAGIMAC 121
Query: 149 PWGLRKKKTSTDGIEIQMATNYAGVFHLLNLMKPSFK--AQPPDRDVRIIVTT------C 200
P+ L S+D IE+Q ATN+ G F L NL+ K A +R+ RI++ +
Sbjct: 122 PFLL-----SSDNIELQFATNHLGHFLLTNLLLERMKKTASESNREGRIVIVSSEGHRFA 176
Query: 201 FLQAMGKCNVEDPLWLHAPFKNSRELFSSSKLQLSLAMLHLQRLLITEAGNSAKDGRSGK 260
+ + + + D N+ + + SKL L L RL G
Sbjct: 177 YREGVQFDKINDEARY-----NTLQAYGQSKLGNILHATELARLF----------KEQGV 221
Query: 261 NVTVTVVQPG-----LMRSPSLRRVVSNGSXXXXXXXXXXXXXPFLWLLTKSGYRGAQTI 315
N+T + PG L+R S + N + KS +GA T
Sbjct: 222 NITANSLHPGSIMTNLLRYHSFINTIGNAVGK---------------YVLKSIPQGAATT 266
Query: 316 IYSITTPELEEVNRTDDEVKYIANCSIVNFARKEFYDKELQEKLYENTIK 365
Y+ P+ + V+ +Y+ + +I + + DK+L +KL+E +++
Sbjct: 267 CYAALHPQAKGVSG-----EYLMDNNISD-PNSQGKDKDLAKKLWEFSLR 310
>At5g50130 [Q] KOG1208 Dehydrogenases with different specificities (related to
short-chain alcohol dehydrogenases)
Length = 332
Score = 49.7 bits (117), Expect = 8e-06
Identities = 73/291 (25%), Positives = 124/291 (42%), Gaps = 41/291 (14%)
Query: 57 IVTGGTTQSMGTSVVLDMARRGAQMIVLCRKIDEWSEEWCEQMRELTGNELIYLEQCDLS 116
I+TGGT+ +G +A+RG ++++ R + + +RE ++I E DLS
Sbjct: 40 IITGGTS-GIGAETARVLAKRGVRVVMAVRDMKKAEMVKERIIRENPEADIILFE-IDLS 97
Query: 117 DLFEVRKFATKWLDNAPPRRLDGIIVMSGDCEPWGLRKKKTSTDGIEIQMATNYAGVFHL 176
L V +F +++L P L+ +I +G P + S + IE+ ATN+ G + L
Sbjct: 98 SLSSVARFCSQFLSQDLP--LNILINNAGVFSP----NLEFSEEKIELTFATNFLGHYLL 151
Query: 177 LNLM--KPSFKAQPPDRDVRIIVTTCFLQAMGKCNVED-PLWLHAPFKNSRELFSSSKLQ 233
++ K A+ + RII + + K + P LH N ++ SKL
Sbjct: 152 TEMLIEKMIDTAEKSGIEGRIINLSSVIHNWVKPDCFSFPKLLHPIRYNGTRAYAQSKLA 211
Query: 234 LSLAMLHLQRLLITEAGNSAKDGRSGKNVTVTVVQPGLMRSPSLRRVVSNGSXXXXXXXX 293
+LH + L KD + NVT+ V PG++++ +R G
Sbjct: 212 ---TILHAKAL-----SKQLKDRNA--NVTINAVHPGIVKTGIIR--AHKGLFTASK--- 256
Query: 294 XXXXXPFLWLLTKSGYRGAQTIIYSITTPELEEVNRTDDEVKYIANCSIVN 344
L KS +GA T Y + E + ++ KY A+C+ N
Sbjct: 257 ----------LLKSISQGAATTCYVALSNETKGLSG-----KYFADCNETN 292
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.318 0.135 0.404
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,242,078
Number of Sequences: 60738
Number of extensions: 940266
Number of successful extensions: 2337
Number of sequences better than 1.0e-05: 27
Number of HSP's better than 0.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 25
Number of HSP's that attempted gapping in prelim test: 2278
Number of HSP's gapped (non-prelim): 31
length of query: 405
length of database: 30,389,216
effective HSP length: 109
effective length of query: 296
effective length of database: 23,768,774
effective search space: 7035557104
effective search space used: 7035557104
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)