ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIV2085 good R KOG0646 General function prediction only WD40 repeat protein
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIV2085 710885 712408 508
(508 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YNL182c [R] KOG0646 WD40 repeat protein 397 e-110
SPAC13G7.08c [R] KOG0646 WD40 repeat protein 91 4e-18
7290219 [R] KOG0646 WD40 repeat protein 80 9e-15
Hs14765579 [R] KOG0646 WD40 repeat protein 66 1e-10
CE03583 [R] KOG0646 WD40 repeat protein 54 4e-07
At3g49180 [R] KOG0646 WD40 repeat protein 53 1e-06
>YNL182c [R] KOG0646 WD40 repeat protein
Length = 555
Score = 397 bits (1021), Expect = e-110
Identities = 240/572 (41%), Positives = 342/572 (58%), Gaps = 89/572 (15%)
Query: 1 MDEQVIFTSNTAGTVATLHSLEQSSLRQCQTESKFSSCVVKQKYLFVAQSRKALIQVYDL 60
MDEQVIFT+NT+GT+A++HS EQ +LRQC T+S+ S V KYLF+AQ++KALI VY+L
Sbjct: 1 MDEQVIFTTNTSGTIASVHSFEQINLRQCSTQSRNSCVQVGNKYLFIAQAQKALINVYNL 60
Query: 61 HGSNKRESVEQRLPVPEVLQALECVDEDG--------------------LLLGATDSGKL 100
GS KRESVEQRLP+PE+L+ LE V+ DG LLLG+T+SGKL
Sbjct: 61 SGSFKRESVEQRLPLPEILKCLEVVENDGVQYDRIQGVNHNLPDFNLPYLLLGSTESGKL 120
Query: 101 YIWQLASGNLLNVKPMAHYQGIVKIKSICHGKYIVTAGSDSRLIFWQTMDLV--QKDEPK 158
YIW+L SG LLNVKPMAHYQ I KIKSI +GKYI+T+G+DSR+I WQT+DLV D+PK
Sbjct: 121 YIWELNSGILLNVKPMAHYQSITKIKSILNGKYIITSGNDSRVIIWQTVDLVSASNDDPK 180
Query: 159 PLFIIHDHSLPVTDFIFSNTLGHSL---DGKLYTVSKDMSLRCY---------------- 199
PL I+HDH+LPVTDF S++ G L D KL+TVS+D ++RCY
Sbjct: 181 PLCILHDHTLPVTDFQVSSSQGKFLSCTDTKLFTVSQDATIRCYDLSLIGSKKKQKANEN 240
Query: 200 QVSVDHEPTCIATFTFPSSLNCVSLDTADRAIYVGTDTGVIQIPLYYKVSNSKIINLLQP 259
VS+ P +ATFT P S+ + LD ADRA Y+GT G + L+YK+ + I+NLLQ
Sbjct: 241 DVSIGKTPVLLATFTTPYSIKSIVLDPADRACYIGTAEGCFSLNLFYKLKGNAIVNLLQS 300
Query: 260 ------NESKIYSITE---ITPGAMEPDLSSREKLFSIGQILCARIVHNNTTSVAXXXXX 310
+ +++S+ + +T G E DL + L+++GQ++C ++++N + +
Sbjct: 301 AGVNTVQKGRVFSLVQRNSLTGGENE-DL---DALYAMGQLVCENVLNSNVSCLEISMDG 356
Query: 311 XXXXXXXXXXKCTVTEIFSNQPLKEIRALSTN-DSTGPVSNLIVFPVTQQSESLL--DVT 367
K ++ EI+S Q ++ I+ L+T+ DS G V+NL+ P + +LL +
Sbjct: 357 TLLLIGDTEGKVSIAEIYSKQIIRTIQTLTTSQDSVGEVTNLLTNPYRLERGNLLFEGES 416
Query: 368 KIVKP--------WKFPNLQRAIVDRKH--GINDVYVQFHENSVHN----VLPVSDFDSY 413
K +P K PNLQR I D K+ ++D++ Q E LP++DF++Y
Sbjct: 417 KGKQPSNNNGHNFMKIPNLQRVIFDGKNKGHLHDIWYQIGEPEAETDPNLALPLNDFNAY 476
Query: 414 LDTVASEEHIFHQTGSINSTV----NRVGQTKASMTATAKEXXXXXXXXXXXXXXXQIAQ 469
L+ V ++E IF G ++S V N++ T + + AK+ +I +
Sbjct: 477 LEQVKTQESIFSHIGKVSSNVKVIDNKIDATSSLDSNAAKD--------------EEITE 522
Query: 470 LNGTVASLTDAYKELRKMHEDLMKEHQQLLSK 501
L + +LT AYKELR MHE L +EHQQ+L K
Sbjct: 523 LKTNIEALTHAYKELRDMHEKLYEEHQQMLDK 554
>SPAC13G7.08c [R] KOG0646 WD40 repeat protein
Length = 446
Score = 90.9 bits (224), Expect = 4e-18
Identities = 67/230 (29%), Positives = 110/230 (47%), Gaps = 20/230 (8%)
Query: 24 SSLRQCQTESKFSSCVVKQKYLFVAQSRKALIQVYDLHGSNKRESVEQRLPVPEVLQALE 83
S+ RQ + +K ++C L +R L ++H K E ++Q + +PE+L ++
Sbjct: 30 STFRQ-SSPAKNATCTTLNHLLSAQHTRPQL----NIHNFGK-EILDQSIILPEILICVQ 83
Query: 84 CVDEDGLLLGATDSGKLYIWQLASGNLLNVKPMAHYQGIVKIKSICHGKYIVTAGSDSRL 143
L T+ G LYIW L SG L+ AHYQ + +K G + TA +D +
Sbjct: 84 SSPCGSWLAAGTEKGNLYIWSLKSGALIYFF-RAHYQPLTILKFSNDGMVLFTASNDGDV 142
Query: 144 IFWQTMDLVQKDEP--------KPLFIIHDHSLPVTDFIFSNTLGHSLDGKLYTVSKDMS 195
W LV ++ K + H + G + G+LYT S+D +
Sbjct: 143 FAWLISTLVDQNSTFETSNSSVKAISHFSGHKRSIVSMEIGP--GPIVSGRLYTASEDNT 200
Query: 196 LRCYQVSVDHEPTCIATFTFPSSLNCVSLDTADRAIYVGTDTGVIQIPLY 245
+R + VS + T IA PS+ +C+++D ++R +YVG + G+I IPLY
Sbjct: 201 IRIWDVSTGNLLTTIA---LPSTPSCMTVDPSERVVYVGNEKGIIWIPLY 247
>7290219 [R] KOG0646 WD40 repeat protein
Length = 506
Score = 79.7 bits (195), Expect = 9e-15
Identities = 61/210 (29%), Positives = 101/210 (48%), Gaps = 19/210 (9%)
Query: 39 VVKQKYLFVAQSRKALIQVYDLHGSNKRESVEQ-RLPVPEVLQALECVDEDGLLLGATDS 97
++ Y+ A S K L+ V+ + NK+E + R VP + AL + DG L A
Sbjct: 47 MIHLNYVMAANSAKPLLHVWPI---NKQEQMAGLRFVVPGKVNAL-ALTPDGNFLVAGIQ 102
Query: 98 GKLYIWQLASGNLLNVKPMAHYQGIVKIKSICHGKYIVTAGSDSRLIFWQTMDLVQ---- 153
+Y+W ++SG +LN HYQ I ++ +G++ ++ G D ++ W
Sbjct: 103 ENIYLWHMSSGRMLNTLSK-HYQAITCLRFTDNGEHFISGGKDGAVLVWDLTFSAAPLDT 161
Query: 154 ---KDEPKPLFIIHDHSLPVTDFIFSNTLGHSLDGKLYTVSKDMSLRCYQVSVDHEPTCI 210
KD +PL+ +DH L VTD ++S G + LYTVS D RC +V +
Sbjct: 162 GGGKDSTEPLYSFNDHGLAVTD-LYSGIGG--IRSYLYTVSLD---RCCKVYDLCGGVLL 215
Query: 211 ATFTFPSSLNCVSLDTADRAIYVGTDTGVI 240
+ FP +L+ V + + +YVG+ G +
Sbjct: 216 LSVVFPVALHSVIVSKMETRVYVGSSDGKV 245
>Hs14765579 [R] KOG0646 WD40 repeat protein
Length = 432
Score = 66.2 bits (160), Expect = 1e-10
Identities = 49/209 (23%), Positives = 102/209 (48%), Gaps = 19/209 (9%)
Query: 43 KYLFVAQSRKALIQVYDLHGSNKRESVEQRLPVPEVLQALECVDEDGLLLGATDSGKLYI 102
+YL AQ K I ++L +++ ++Q++ P + L +GL + A + +++
Sbjct: 50 EYLLAAQLGKNYISAWELQ---RKDQLQQKIMCPGPVTCLTA-SPNGLYVLAGVAESIHL 105
Query: 103 WQLASGNLLNVKPMAHYQGIVKIKSICHGKYIVTAGSDSRLIFWQTMDLVQKDE---PKP 159
W++++GNLL + HYQ + ++ + ++ G D ++ W ++Q D P P
Sbjct: 106 WEVSTGNLLVILSR-HYQDVSCLQFTGDSSHFISGGKDCLVLVWSLCSVLQADPSRIPAP 164
Query: 160 LFIIHDHSLPVTDFI--FSNTLGHSLDGKLYTVSKDMSLRCYQVSVDHEPTCIATFTFPS 217
+ H+LP+TD F L ++ T S D +++ ++VS + + F
Sbjct: 165 RHVWSHHALPITDLHCGFGGPL-----ARVATSSLDQTVKLWEVS---SGELLLSVLFDV 216
Query: 218 SLNCVSLDTADRAIYVGTDTG-VIQIPLY 245
S+ V++D A+ ++ G G + Q+ L+
Sbjct: 217 SIMAVTMDLAEHHMFCGGSEGSIFQVDLF 245
>CE03583 [R] KOG0646 WD40 repeat protein
Length = 529
Score = 54.3 bits (129), Expect = 4e-07
Identities = 50/207 (24%), Positives = 92/207 (44%), Gaps = 16/207 (7%)
Query: 43 KYLFVAQSRKALIQVYDLHGSNKRESVEQRLPVPEVLQALECVDEDGLLLGATDSGKLYI 102
+++ + + L+ V +H ++ Q+ +P + A+ D G + + +LY
Sbjct: 67 EHVVITTKERPLVHVLAVH---PKDRFHQKCVLPGPVSAIVS-DNSGHFVFMSIKRQLYC 122
Query: 103 WQLASGNLLNVKPMAHYQGIVKIKSICHGKYIVTAGSDSRLIFWQTMDLVQKDEP---KP 159
W L++G LL+V AHYQ I KI I TA D + + DLV D P
Sbjct: 123 WLLSTGELLSVID-AHYQNITKIVISDDDSMIFTASKDGAVHGYLVTDLVSADRDHTVAP 181
Query: 160 LFIIHDHSLPVTDFIFSNTLGHSLDGKLYTVSKDMSLRCYQVSVDHEPTCIATFTFPSSL 219
H+L ++D +N + ++ + D + +S+D + I + L
Sbjct: 182 FRKWASHTLSISDLKITN----GSNPRVLSAGADHIACLHSISMD---SVILKASSDRPL 234
Query: 220 NCVSLDTADRAIYVGTDTG-VIQIPLY 245
++D A+ I++GT+ G + QI L+
Sbjct: 235 TACAIDPAETRIFIGTEVGNIAQINLF 261
>At3g49180 [R] KOG0646 WD40 repeat protein
Length = 438
Score = 52.8 bits (125), Expect = 1e-06
Identities = 40/171 (23%), Positives = 76/171 (44%), Gaps = 12/171 (7%)
Query: 77 EVLQALECVDEDGLLLGATDSGKLYIWQLASGNLLNVKPMAHYQGIVKIKSICHGKYIVT 136
E ++AL +E L+G SG +Y+W++A+G LL K HY+ + + +V+
Sbjct: 79 EPIKALAANNEGTYLVGGGISGDIYLWEVATGKLLK-KWHGHYRSVTCLVFSGDDSLLVS 137
Query: 137 AGSDSRLIFW---QTMDLVQKDEPKPLF--IIHDHSLPVTDFIFSNTLGHSLDGKLYTVS 191
D + W + D Q+ + L+ ++H++ VTD + + + + S
Sbjct: 138 GSQDGSIRVWSLIRLFDDFQRQQGNTLYEHNFNEHTMSVTDIVIDY---GGCNAVIISSS 194
Query: 192 KDMSLRCYQVSVDHEPTCIATFTFPSSLNCVSLDTADRAIYVGTDTGVIQI 242
+D + + + +S + FPS +N ++LD Y G I I
Sbjct: 195 EDRTCKVWSLS---RGKLLKNIIFPSVINALALDPGGCVFYAGARDSKIYI 242
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.316 0.131 0.373
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,178,347
Number of Sequences: 60738
Number of extensions: 1074964
Number of successful extensions: 3388
Number of sequences better than 1.0e-05: 6
Number of HSP's better than 0.0 without gapping: 1
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 3368
Number of HSP's gapped (non-prelim): 7
length of query: 508
length of database: 30,389,216
effective HSP length: 111
effective length of query: 397
effective length of database: 23,647,298
effective search space: 9387977306
effective search space used: 9387977306
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)