ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIV2104 check: MH D KOG0590 Cell cycle control, cell division, chromosome partitioning Checkpoint kinase and related serine/threonine protein kinases
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIV2104 714473 716794 774
(774 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YNL183c [D] KOG0590 Checkpoint kinase and related serine/threoni... 764 0.0
YDL214c [D] KOG0590 Checkpoint kinase and related serine/threoni... 372 e-103
SPCC1020.10 [D] KOG0590 Checkpoint kinase and related serine/thr... 340 4e-93
YDL025c [D] KOG0590 Checkpoint kinase and related serine/threoni... 283 9e-76
YOR267c [D] KOG0590 Checkpoint kinase and related serine/threoni... 276 1e-73
SPAC22G7.08 [D] KOG0590 Checkpoint kinase and related serine/thr... 202 1e-51
YCR008w [D] KOG0590 Checkpoint kinase and related serine/threoni... 167 6e-41
SPAC29A4.16 [D] KOG0590 Checkpoint kinase and related serine/thr... 160 5e-39
SPCC70.05c [D] KOG0590 Checkpoint kinase and related serine/thre... 142 1e-33
YKL168c [D] KOG0590 Checkpoint kinase and related serine/threoni... 132 2e-30
YJL165c [D] KOG0590 Checkpoint kinase and related serine/threoni... 130 8e-30
SPBC21.07c [D] KOG0590 Checkpoint kinase and related serine/thre... 109 2e-23
YJR059w [T] KOG0583 Serine/threonine protein kinase 105 3e-22
CE21879 [D] KOG0590 Checkpoint kinase and related serine/threoni... 103 1e-21
Hs4502803 [D] KOG0590 Checkpoint kinase and related serine/threo... 103 1e-21
At4g33950 [T] KOG0583 Serine/threonine protein kinase 100 1e-20
CE21086 [D] KOG0590 Checkpoint kinase and related serine/threoni... 100 1e-20
YDR477w [T] KOG0583 Serine/threonine protein kinase 99 2e-20
Hs4557439 [R] KOG0594 Protein kinase PCTAIRE and related kinases 99 2e-20
CE26422 [D] KOG0600 Cdc2-related protein kinase 99 2e-20
CE20636 [D] KOG0590 Checkpoint kinase and related serine/threoni... 99 3e-20
CE27768 [R] KOG0586 Serine/threonine protein kinase 97 9e-20
CE23838 [R] KOG0586 Serine/threonine protein kinase 97 9e-20
YCL024w [T] KOG0583 Serine/threonine protein kinase 97 1e-19
At5g66880 [T] KOG0583 Serine/threonine protein kinase 96 2e-19
Hs20562757 [T] KOG0660 Mitogen-activated protein kinase 96 2e-19
At5g08590 [T] KOG0583 Serine/threonine protein kinase 96 2e-19
At3g50500 [T] KOG0583 Serine/threonine protein kinase 96 2e-19
At2g23030 [T] KOG0583 Serine/threonine protein kinase 96 2e-19
Hs9845489 [R] KOG0586 Serine/threonine protein kinase 96 3e-19
Hs9845487 [R] KOG0586 Serine/threonine protein kinase 96 3e-19
Hs22062450 [R] KOG0586 Serine/threonine protein kinase 96 3e-19
At5g63650 [T] KOG0583 Serine/threonine protein kinase 96 3e-19
At5g25110 [T] KOG0583 Serine/threonine protein kinase 96 3e-19
At5g10270 [D] KOG0600 Cdc2-related protein kinase 96 3e-19
Hs16936528 [R] KOG0594 Protein kinase PCTAIRE and related kinases 95 4e-19
At5g64960 [D] KOG0600 Cdc2-related protein kinase 95 4e-19
Hs13899225 [R] KOG0586 Serine/threonine protein kinase 95 5e-19
SPBC1604.14c [T] KOG0578 p21-activated serine/threonine protein ... 94 8e-19
SPAC23H4.02 [T] KOG0583 Serine/threonine protein kinase 94 8e-19
At1g67580 [R] KOG0663 Protein kinase PITSLRE and related kinases 94 8e-19
At1g18670 [D] KOG0600 Cdc2-related protein kinase 94 8e-19
At1g10940 [T] KOG0583 Serine/threonine protein kinase 94 8e-19
At5g60550 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase k... 94 1e-18
7296346 [R] KOG0663 Protein kinase PITSLRE and related kinases 94 1e-18
YOR233w [T] KOG0583 Serine/threonine protein kinase 93 1e-18
CE26076 [D] KOG0590 Checkpoint kinase and related serine/threoni... 93 1e-18
At4g18700 [T] KOG0583 Serine/threonine protein kinase 93 1e-18
7301213 [R] KOG0589 Serine/threonine protein kinase 93 1e-18
SPCC1259.13 [D] KOG0590 Checkpoint kinase and related serine/thr... 93 2e-18
Hs4502709 [R] KOG0594 Protein kinase PCTAIRE and related kinases 93 2e-18
At5g39420 [D] KOG0600 Cdc2-related protein kinase 93 2e-18
At3g06030 [T] KOG0198 MEKK and related serine/threonine protein ... 93 2e-18
SPAC57A10.02 [D] KOG0588 Serine/threonine protein kinase 92 2e-18
CE18454 [T] KOG4717 Serine/threonine protein kinase 92 2e-18
At5g39440 [T] KOG0583 Serine/threonine protein kinase 92 2e-18
At1g18150 [T] KOG0660 Mitogen-activated protein kinase 92 2e-18
CE29466 [T] KOG0665 Jun-N-terminal kinase (JNK) 92 3e-18
At5g63370 [R] KOG0663 Protein kinase PITSLRE and related kinases 92 3e-18
At1g60940 [T] KOG0583 Serine/threonine protein kinase 92 3e-18
7302464 [R] KOG0586 Serine/threonine protein kinase 92 3e-18
Hs8923922 [R] KOG0586 Serine/threonine protein kinase 92 4e-18
CE12478 [D] KOG0590 Checkpoint kinase and related serine/threoni... 92 4e-18
At5g10930 [T] KOG0583 Serine/threonine protein kinase 92 4e-18
7300650 [R] KOG0594 Protein kinase PCTAIRE and related kinases 92 4e-18
Hs7657214 [T] KOG0583 Serine/threonine protein kinase 91 5e-18
YHL007c [T] KOG0578 p21-activated serine/threonine protein kinase 91 7e-18
HsM4505103 [R] KOG0586 Serine/threonine protein kinase 91 7e-18
Hs20986531 [T] KOG0660 Mitogen-activated protein kinase 91 7e-18
At1g29230 [T] KOG0583 Serine/threonine protein kinase 91 7e-18
7299322 [R] KOG0611 Predicted serine/threonine protein kinase 91 7e-18
YBR274w [D] KOG0590 Checkpoint kinase and related serine/threoni... 91 9e-18
Hs21361643 [T] KOG4717 Serine/threonine protein kinase 91 9e-18
Hs20986529 [T] KOG0660 Mitogen-activated protein kinase 91 9e-18
CE24971 [T] KOG0660 Mitogen-activated protein kinase 91 9e-18
CE01583 [T] KOG0660 Mitogen-activated protein kinase 91 9e-18
At1g01140 [T] KOG0583 Serine/threonine protein kinase 91 9e-18
CE17305 [T] KOG0665 Jun-N-terminal kinase (JNK) 90 1e-17
CE12408 [T] KOG0661 MAPK related serine/threonine protein kinase 90 1e-17
At4g30960 [T] KOG0583 Serine/threonine protein kinase 90 1e-17
At4g29810 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 90 1e-17
At2g26980 [T] KOG0583 Serine/threonine protein kinase 90 1e-17
7299437 [R] KOG0586 Serine/threonine protein kinase 90 1e-17
CE26793_1 [R] KOG0611 Predicted serine/threonine protein kinase 90 1e-17
CE28479 [T] KOG0583 Serine/threonine protein kinase 90 2e-17
At1g51660 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 90 2e-17
YAL017w [T] KOG1152 Signal transduction serine/threonine kinase ... 89 2e-17
SPCC74.03c [T] KOG0583 Serine/threonine protein kinase 89 2e-17
SPCC297.03 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase ... 89 2e-17
Hs7661974 [T] KOG0583 Serine/threonine protein kinase 89 2e-17
At5g45810 [T] KOG0583 Serine/threonine protein kinase 89 2e-17
At3g29160 [T] KOG0583 Serine/threonine protein kinase 89 2e-17
At1g78290 [T] KOG0583 Serine/threonine protein kinase 89 2e-17
At1g54960 [T] KOG0198 MEKK and related serine/threonine protein ... 89 2e-17
At1g09000 [T] KOG0198 MEKK and related serine/threonine protein ... 89 2e-17
SPBC4F6.06 [T] KOG0583 Serine/threonine protein kinase 89 3e-17
SPBC32H8.10 [D] KOG0600 Cdc2-related protein kinase 89 3e-17
Hs11496279 [T] KOG0661 MAPK related serine/threonine protein kinase 89 3e-17
At1g73690 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymera... 89 3e-17
SPAC23C11.16 [D] KOG0575 Polo-like serine/threonine protein kinase 89 3e-17
7303211 [T] KOG4717 Serine/threonine protein kinase 89 3e-17
7302570 [R] KOG0586 Serine/threonine protein kinase 89 3e-17
7298323 [D] KOG0590 Checkpoint kinase and related serine/threoni... 89 3e-17
Hs7662170 [R] KOG0611 Predicted serine/threonine protein kinase 88 4e-17
CE21213 [UT] KOG0662 Cyclin-dependent kinase CDK5 88 4e-17
At5g58380 [T] KOG0583 Serine/threonine protein kinase 88 4e-17
At1g74330 [D] KOG0600 Cdc2-related protein kinase 88 4e-17
7299438 [R] KOG0586 Serine/threonine protein kinase 88 4e-17
YDR507c [D] KOG0588 Serine/threonine protein kinase 88 6e-17
Hs4502731 [R] KOG0663 Protein kinase PITSLRE and related kinases 88 6e-17
Hs16950647 [R] KOG0663 Protein kinase PITSLRE and related kinases 88 6e-17
At2g34180 [T] KOG0583 Serine/threonine protein kinase 88 6e-17
At1g48260 [T] KOG0583 Serine/threonine protein kinase 88 6e-17
7290565 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase... 88 6e-17
Hs7382496 [T] KOG0578 p21-activated serine/threonine protein kinase 87 7e-17
Hs4505599 [T] KOG0578 p21-activated serine/threonine protein kinase 87 7e-17
Hs16357494 [R] KOG0663 Protein kinase PITSLRE and related kinases 87 7e-17
Hs16357492 [R] KOG0663 Protein kinase PITSLRE and related kinases 87 7e-17
CE01761 [R] KOG0663 Protein kinase PITSLRE and related kinases 87 7e-17
At4g13020 [T] KOG0661 MAPK related serine/threonine protein kinase 87 7e-17
At3g17510 [T] KOG0583 Serine/threonine protein kinase 87 7e-17
7298926 [T] KOG0578 p21-activated serine/threonine protein kinase 87 7e-17
CE02602_1 [T] KOG0660 Mitogen-activated protein kinase 87 7e-17
YGL179c [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kin... 87 1e-16
Hs6031180 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and... 87 1e-16
Hs5803088 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and... 87 1e-16
Hs13569922 [R] KOG0611 Predicted serine/threonine protein kinase 87 1e-16
At5g50860 [D] KOG0600 Cdc2-related protein kinase 87 1e-16
At4g24400 [T] KOG0583 Serine/threonine protein kinase 87 1e-16
At3g18040 [T] KOG0660 Mitogen-activated protein kinase 87 1e-16
Hs7705551 [T] KOG0661 MAPK related serine/threonine protein kinase 87 1e-16
Hs21361433 [D] KOG0575 Polo-like serine/threonine protein kinase 87 1e-16
Hs20545245 [D] KOG0588 Serine/threonine protein kinase 87 1e-16
Hs16357498 [R] KOG0663 Protein kinase PITSLRE and related kinases 87 1e-16
Hs16357486 [R] KOG0663 Protein kinase PITSLRE and related kinases 87 1e-16
Hs16357484 [R] KOG0663 Protein kinase PITSLRE and related kinases 87 1e-16
Hs16357482 [R] KOG0663 Protein kinase PITSLRE and related kinases 87 1e-16
Hs16357480 [R] KOG0663 Protein kinase PITSLRE and related kinases 87 1e-16
ECU08g1790 [D] KOG0600 Cdc2-related protein kinase 87 1e-16
At4g40010 [T] KOG0583 Serine/threonine protein kinase 87 1e-16
At3g01090 [T] KOG0583 Serine/threonine protein kinase 87 1e-16
At1g73670 [T] KOG0660 Mitogen-activated protein kinase 87 1e-16
At1g30270 [T] KOG0583 Serine/threonine protein kinase 87 1e-16
SPAC644.06c [D] KOG0588 Serine/threonine protein kinase 86 2e-16
HsM7657627 [D] KOG0575 Polo-like serine/threonine protein kinase 86 2e-16
Hs4505601 [T] KOG0578 p21-activated serine/threonine protein kinase 86 2e-16
Hs16357496 [R] KOG0663 Protein kinase PITSLRE and related kinases 86 2e-16
Hs16332372 [R] KOG0663 Protein kinase PITSLRE and related kinases 86 2e-16
Hs16332370 [R] KOG0663 Protein kinase PITSLRE and related kinases 86 2e-16
Hs16332368 [R] KOG0663 Protein kinase PITSLRE and related kinases 86 2e-16
Hs16332366 [R] KOG0663 Protein kinase PITSLRE and related kinases 86 2e-16
Hs16332364 [R] KOG0663 Protein kinase PITSLRE and related kinases 86 2e-16
Hs16332362 [R] KOG0663 Protein kinase PITSLRE and related kinases 86 2e-16
Hs16332360 [R] KOG0663 Protein kinase PITSLRE and related kinases 86 2e-16
Hs16332358 [R] KOG0663 Protein kinase PITSLRE and related kinases 86 2e-16
Hs10835055 [R] KOG0663 Protein kinase PITSLRE and related kinases 86 2e-16
YPL141c [T] KOG0583 Serine/threonine protein kinase 86 2e-16
SPCC4G3.08 [RT] KOG0598 Ribosomal protein S6 kinase and related ... 86 2e-16
Hs7706445 [T] KOG0664 Nemo-like MAPK-related serine/threonine pr... 86 2e-16
Hs5453964 [T] KOG0583 Serine/threonine protein kinase 86 2e-16
CE16081 [T] KOG0583 Serine/threonine protein kinase 86 2e-16
At5g19010 [T] KOG0660 Mitogen-activated protein kinase 86 2e-16
At5g01810 [T] KOG0583 Serine/threonine protein kinase 86 2e-16
At4g10010 [D] KOG0600 Cdc2-related protein kinase 86 2e-16
At2g42880 [T] KOG0660 Mitogen-activated protein kinase 86 2e-16
At2g38490 [T] KOG0583 Serine/threonine protein kinase 86 2e-16
Hs7662388 [T] KOG0661 MAPK related serine/threonine protein kinase 86 3e-16
At4g26070 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 86 3e-16
At1g54610 [D] KOG0600 Cdc2-related protein kinase 86 3e-16
YKL101w [D] KOG0588 Serine/threonine protein kinase 85 4e-16
Hs4502743 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymera... 85 4e-16
Hs20547806 [R] KOG0589 Serine/threonine protein kinase 85 4e-16
CE28218 [D] KOG0588 Serine/threonine protein kinase 85 4e-16
CE06762 [T] KOG0660 Mitogen-activated protein kinase 85 4e-16
At2g30360 [T] KOG0583 Serine/threonine protein kinase 85 4e-16
7296451 [D] KOG0600 Cdc2-related protein kinase 85 4e-16
7291442 [D] KOG0669 Cyclin T-dependent kinase CDK9 85 4e-16
YLR096w [T] KOG0583 Serine/threonine protein kinase 85 5e-16
Hs18552621 [R] KOG0597 Serine-threonine protein kinase FUSED 85 5e-16
ECU08g1920 [R] KOG0594 Protein kinase PCTAIRE and related kinases 85 5e-16
At3g48750 [R] KOG0594 Protein kinase PCTAIRE and related kinases 85 5e-16
7300149 [T] KOG0578 p21-activated serine/threonine protein kinase 85 5e-16
7297009 [R] KOG0593 Predicted protein kinase KKIAMRE 85 5e-16
Hs4506085 [T] KOG0660 Mitogen-activated protein kinase 84 6e-16
CE27670 [T] KOG0578 p21-activated serine/threonine protein kinase 84 6e-16
CE17284 [T] KOG0583 Serine/threonine protein kinase 84 6e-16
CE00315 [R] KOG0594 Protein kinase PCTAIRE and related kinases 84 6e-16
YJL095w [T] KOG0198 MEKK and related serine/threonine protein ki... 84 8e-16
CE27220 [T] KOG0660 Mitogen-activated protein kinase 84 8e-16
CE23001 [R] KOG0589 Serine/threonine protein kinase 84 8e-16
At3g45240 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase k... 84 8e-16
At1g18040 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymera... 84 8e-16
7303804 [R] KOG0663 Protein kinase PITSLRE and related kinases 84 8e-16
SPAC9G1.02 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 an... 84 1e-15
ECU05g1510 [TDK] KOG0668 Casein kinase II alpha subunit 84 1e-15
ECU03g0980 [T] KOG0583 Serine/threonine protein kinase 84 1e-15
At5g01820 [T] KOG0583 Serine/threonine protein kinase 84 1e-15
At1g12680 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 84 1e-15
At1g03740 [D] KOG0600 Cdc2-related protein kinase 84 1e-15
7294217 [D] KOG0588 Serine/threonine protein kinase 84 1e-15
Hs4826684_1 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase... 84 1e-15
YER129w [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kin... 83 1e-15
SPAC1F5.09c [T] KOG0578 p21-activated serine/threonine protein k... 83 1e-15
Hs4502741 [R] KOG0594 Protein kinase PCTAIRE and related kinases 83 1e-15
Hs16507245 [T] KOG0583 Serine/threonine protein kinase 83 1e-15
At4g22940 [D] KOG0600 Cdc2-related protein kinase 83 1e-15
7297080 [T] KOG0583 Serine/threonine protein kinase 83 1e-15
SPCC18B5.11c [D] KOG0615 Serine/threonine protein kinase Chk2 an... 83 2e-15
At5g44290 [D] KOG0600 Cdc2-related protein kinase 83 2e-15
At5g07070 [T] KOG0583 Serine/threonine protein kinase 83 2e-15
At2g25090 [T] KOG0583 Serine/threonine protein kinase 83 2e-15
SPAC1F3.02c [T] KOG0198 MEKK and related serine/threonine protei... 82 2e-15
HsM8923212 [T] KOG4717 Serine/threonine protein kinase 82 2e-15
Hs4506785 [T] KOG0660 Mitogen-activated protein kinase 82 2e-15
ECU11g1290 [R] KOG0663 Protein kinase PITSLRE and related kinases 82 2e-15
At5g45820 [T] KOG0583 Serine/threonine protein kinase 82 2e-15
At3g21220 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 82 2e-15
At1g53570 [T] KOG0198 MEKK and related serine/threonine protein ... 82 2e-15
7297680 [R] KOG0594 Protein kinase PCTAIRE and related kinases 82 2e-15
Hs4758652 [R] KOG0593 Predicted protein kinase KKIAMRE 82 3e-15
Hs4505695 [T] KOG0592 3-phosphoinositide-dependent protein kinas... 82 3e-15
CE20564 [T] KOG0578 p21-activated serine/threonine protein kinase 82 3e-15
CE05425 [T] KOG0578 p21-activated serine/threonine protein kinase 82 3e-15
At1g33770 [D] KOG0600 Cdc2-related protein kinase 82 3e-15
SPBC1D7.05c [T] KOG0198 MEKK and related serine/threonine protei... 82 4e-15
Hs4826675 [UT] KOG0662 Cyclin-dependent kinase CDK5 82 4e-15
Hs14042966 [T] KOG0583 Serine/threonine protein kinase 82 4e-15
CE28643 [T] KOG0583 Serine/threonine protein kinase 82 4e-15
CE07458 [T] KOG0583 Serine/threonine protein kinase 82 4e-15
At5g56580 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 82 4e-15
At1g50230 [R] KOG0597 Serine-threonine protein kinase FUSED 82 4e-15
7301110 [T] KOG0660 Mitogen-activated protein kinase 82 4e-15
7296128 [T] KOG0583 Serine/threonine protein kinase 82 4e-15
7295173 [T] KOG0664 Nemo-like MAPK-related serine/threonine prot... 82 4e-15
7293601 [T] KOG0577 Serine/threonine protein kinase 82 4e-15
YOL045w [T] KOG1152 Signal transduction serine/threonine kinase ... 81 5e-15
YKL139w [D] KOG0600 Cdc2-related protein kinase 81 5e-15
CE27899 [D] KOG0590 Checkpoint kinase and related serine/threoni... 81 5e-15
Hs19311016_1 [R] KOG0589 Serine/threonine protein kinase 81 5e-15
SPAC2F3.15 [D] KOG0600 Cdc2-related protein kinase 81 7e-15
Hs7706401 [T] KOG0577 Serine/threonine protein kinase 81 7e-15
Hs4759208 [T] KOG0577 Serine/threonine protein kinase 81 7e-15
Hs4506081 [T] KOG0665 Jun-N-terminal kinase (JNK) 81 7e-15
Hs20986510 [T] KOG0665 Jun-N-terminal kinase (JNK) 81 7e-15
Hs20986506 [T] KOG0665 Jun-N-terminal kinase (JNK) 81 7e-15
7297578 [T] KOG0661 MAPK related serine/threonine protein kinase 81 7e-15
7293666 [D] KOG0575 Polo-like serine/threonine protein kinase 81 7e-15
7290150 [T] KOG0583 Serine/threonine protein kinase 81 7e-15
YDR122w [T] KOG0583 Serine/threonine protein kinase 80 9e-15
Hs4505569 [R] KOG0593 Predicted protein kinase KKIAMRE 80 9e-15
Hs21237745 [T] KOG0665 Jun-N-terminal kinase (JNK) 80 9e-15
Hs21237742 [T] KOG0665 Jun-N-terminal kinase (JNK) 80 9e-15
At1g07880 [T] KOG0660 Mitogen-activated protein kinase 80 9e-15
YOL113w [T] KOG0578 p21-activated serine/threonine protein kinase 80 1e-14
YCR091w [R] KOG0610 Putative serine/threonine protein kinase 80 1e-14
SPBC16E9.13 [T] KOG0583 Serine/threonine protein kinase 80 1e-14
SPBC12D12.04c [T] KOG0694 Serine/threonine protein kinase 80 1e-14
Hs6005850 [D] KOG0615 Serine/threonine protein kinase Chk2 and r... 80 1e-14
Hs19923464 [T] KOG0577 Serine/threonine protein kinase 80 1e-14
CE21615 [T] KOG0578 p21-activated serine/threonine protein kinase 80 1e-14
At1g69220 [T] KOG0576 Mitogen-activated protein kinase kinase ki... 80 1e-14
7300413 [T] KOG0583 Serine/threonine protein kinase 80 1e-14
7290249 [R] KOG0586 Serine/threonine protein kinase 80 1e-14
YOL100w [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 80 2e-14
SPBC18H10.15 [R] KOG0663 Protein kinase PITSLRE and related kinases 80 2e-14
At3g61960 [OUT] KOG0595 Serine/threonine-protein kinase involved... 80 2e-14
At3g23000 [T] KOG0583 Serine/threonine protein kinase 80 2e-14
7303051 [UT] KOG0662 Cyclin-dependent kinase CDK5 80 2e-14
Hs21361133 [R] KOG0586 Serine/threonine protein kinase 79 2e-14
ECU11g0960 [D] KOG0600 Cdc2-related protein kinase 79 2e-14
CE03811 [R] KOG0663 Protein kinase PITSLRE and related kinases 79 2e-14
At1g53050 [D] KOG0600 Cdc2-related protein kinase 79 2e-14
7302511 [T] KOG0576 Mitogen-activated protein kinase kinase kina... 79 2e-14
Hs5453978 [T] KOG0614 cGMP-dependent protein kinase 79 3e-14
Hs4502735 [R] KOG0594 Protein kinase PCTAIRE and related kinases 79 3e-14
CE27297 [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 79 3e-14
At3g14720 [T] KOG0660 Mitogen-activated protein kinase 79 3e-14
Hs7661994 [T] KOG0579 Ste20-like serine/threonine protein kinase 79 3e-14
Hs20545357 [T] KOG0583 Serine/threonine protein kinase 79 3e-14
CE27965 [T] KOG0574 STE20-like serine/threonine kinase MST 79 3e-14
CE27726 [T] KOG0574 STE20-like serine/threonine kinase MST 79 3e-14
CE27082 [T] KOG0574 STE20-like serine/threonine kinase MST 79 3e-14
CE18366 [T] KOG0583 Serine/threonine protein kinase 79 3e-14
CE17343 [T] KOG0583 Serine/threonine protein kinase 79 3e-14
CE07064 [T] KOG0574 STE20-like serine/threonine kinase MST 79 3e-14
At1g59580 [T] KOG0660 Mitogen-activated protein kinase 79 3e-14
YPL031c [R] KOG0594 Protein kinase PCTAIRE and related kinases 78 5e-14
Hs7706059 [R] KOG0593 Predicted protein kinase KKIAMRE 78 5e-14
Hs5174701 [T] KOG0579 Ste20-like serine/threonine protein kinase 78 5e-14
Hs14770402 [R] KOG0586 Serine/threonine protein kinase 78 5e-14
CE27573 [T] KOG0198 MEKK and related serine/threonine protein ki... 78 5e-14
CE17815 [K] KOG0666 Cyclin C-dependent kinase CDK8 78 5e-14
CE07737 [T] KOG0198 MEKK and related serine/threonine protein ki... 78 5e-14
At1g71530 [D] KOG0600 Cdc2-related protein kinase 78 5e-14
At1g53510 [T] KOG0660 Mitogen-activated protein kinase 78 5e-14
YNR031c [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and r... 78 6e-14
SPAC890.03 [T] KOG0583 Serine/threonine protein kinase 78 6e-14
Hs5454096 [T] KOG0574 STE20-like serine/threonine kinase MST 78 6e-14
Hs5454094 [T] KOG0574 STE20-like serine/threonine kinase MST 78 6e-14
Hs5453976 [T] KOG0694 Serine/threonine protein kinase 78 6e-14
Hs16178962 [T] KOG0574 STE20-like serine/threonine kinase MST 78 6e-14
YMR001c [D] KOG0575 Polo-like serine/threonine protein kinase 77 8e-14
Hs5031975 [T] KOG0578 p21-activated serine/threonine protein kinase 77 8e-14
Hs17933758 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase ... 77 8e-14
Hs14149671 [TR] KOG0606 Microtubule-associated serine/threonine ... 77 8e-14
CE28251 [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 77 8e-14
At5g63610 [K] KOG0666 Cyclin C-dependent kinase CDK8 77 8e-14
At3g05050 [D] KOG0600 Cdc2-related protein kinase 77 8e-14
At2g43790 [T] KOG0660 Mitogen-activated protein kinase 77 8e-14
At1g66750 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymera... 77 8e-14
Hs5730055 [D] KOG0575 Polo-like serine/threonine protein kinase 77 1e-13
Hs4505649 [R] KOG0594 Protein kinase PCTAIRE and related kinases 77 1e-13
Hs4503069 [T] KOG0660 Mitogen-activated protein kinase 77 1e-13
Hs20986516 [T] KOG0660 Mitogen-activated protein kinase 77 1e-13
Hs20986514 [T] KOG0660 Mitogen-activated protein kinase 77 1e-13
Hs20986512 [T] KOG0660 Mitogen-activated protein kinase 77 1e-13
CE29612 [R] KOG0594 Protein kinase PCTAIRE and related kinases 77 1e-13
CE27574 [T] KOG0665 Jun-N-terminal kinase (JNK) 77 1e-13
CE06686 [T] KOG0660 Mitogen-activated protein kinase 77 1e-13
At4g14580 [T] KOG0583 Serine/threonine protein kinase 77 1e-13
At2g01450 [T] KOG0660 Mitogen-activated protein kinase 77 1e-13
7294866 [K] KOG0666 Cyclin C-dependent kinase CDK8 77 1e-13
YPL209c [D] KOG0580 Serine/threonine protein kinase 77 1e-13
YDL101c [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 77 1e-13
YCR073c [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and r... 77 1e-13
SPBC32C12.03c [T] KOG0583 Serine/threonine protein kinase 77 1e-13
SPBC21.06c [T] KOG0198 MEKK and related serine/threonine protein... 77 1e-13
Hs5453974 [T] KOG0694 Serine/threonine protein kinase 77 1e-13
Hs4557511 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 77 1e-13
Hs17455844 [TR] KOG0606 Microtubule-associated serine/threonine ... 77 1e-13
Hs16950617 [Z] KOG0613 Projectin/twitchin and related proteins 77 1e-13
CE29478 [T] KOG0664 Nemo-like MAPK-related serine/threonine prot... 77 1e-13
CE29477 [T] KOG0664 Nemo-like MAPK-related serine/threonine prot... 77 1e-13
CE29476 [T] KOG0664 Nemo-like MAPK-related serine/threonine prot... 77 1e-13
At3g45640 [T] KOG0660 Mitogen-activated protein kinase 77 1e-13
At3g08730 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 77 1e-13
7291778 [T] KOG0579 Ste20-like serine/threonine protein kinase 77 1e-13
YPR161c [D] KOG0600 Cdc2-related protein kinase 76 2e-13
YLR113w [T] KOG0660 Mitogen-activated protein kinase 76 2e-13
YBR028c [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 76 2e-13
YBL016w [T] KOG0660 Mitogen-activated protein kinase 76 2e-13
SPAC24B11.06c [T] KOG0660 Mitogen-activated protein kinase 76 2e-13
Hs20986501 [T] KOG0660 Mitogen-activated protein kinase 76 2e-13
Hs20986497 [T] KOG0660 Mitogen-activated protein kinase 76 2e-13
Hs14042947 [T] KOG0583 Serine/threonine protein kinase 76 2e-13
ECU02g0550 [D] KOG0575 Polo-like serine/threonine protein kinase 76 2e-13
CE05780 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 76 2e-13
At5g35410 [T] KOG0583 Serine/threonine protein kinase 76 2e-13
At4g19110 [T] KOG0661 MAPK related serine/threonine protein kinase 76 2e-13
At1g09600 [D] KOG0600 Cdc2-related protein kinase 76 2e-13
7303915 [T] KOG0694 Serine/threonine protein kinase 76 2e-13
7303914 [T] KOG0694 Serine/threonine protein kinase 76 2e-13
SPCC16C4.11 [R] KOG0594 Protein kinase PCTAIRE and related kinases 76 2e-13
Hs4507271 [T] KOG0583 Serine/threonine protein kinase 76 2e-13
Hs14771959 [T] KOG0578 p21-activated serine/threonine protein ki... 76 2e-13
Hs10835065 [T] KOG0616 cAMP-dependent protein kinase catalytic s... 76 2e-13
At5g04510 [T] KOG0592 3-phosphoinositide-dependent protein kinas... 76 2e-13
At4g36450 [T] KOG0660 Mitogen-activated protein kinase 76 2e-13
At4g08500 [T] KOG0198 MEKK and related serine/threonine protein ... 76 2e-13
At2g18170 [T] KOG0660 Mitogen-activated protein kinase 76 2e-13
7298652 [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 76 2e-13
YDR490c [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 75 3e-13
YDL108w [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase... 75 3e-13
SPBC11B10.09 [R] KOG0594 Protein kinase PCTAIRE and related kinases 75 3e-13
Hs5453966 [T] KOG0583 Serine/threonine protein kinase 75 3e-13
Hs20128774 [T] KOG0660 Mitogen-activated protein kinase 75 3e-13
Hs16160923 [R] KOG0594 Protein kinase PCTAIRE and related kinases 75 3e-13
CE21025 [D] KOG0580 Serine/threonine protein kinase 75 3e-13
At5g66850 [T] KOG0198 MEKK and related serine/threonine protein ... 75 3e-13
At5g57630 [T] KOG0583 Serine/threonine protein kinase 75 3e-13
7291707 [T] KOG1152 Signal transduction serine/threonine kinase ... 75 3e-13
Hs4506095 [T] KOG0665 Jun-N-terminal kinase (JNK) 75 4e-13
Hs4502747 [D] KOG0669 Cyclin T-dependent kinase CDK9 75 4e-13
Hs20986523 [T] KOG0665 Jun-N-terminal kinase (JNK) 75 4e-13
Hs20543401 [TR] KOG0606 Microtubule-associated serine/threonine ... 75 4e-13
At5g62310 [TR] KOG0606 Microtubule-associated serine/threonine k... 75 4e-13
Hs14670383 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 75 5e-13
CE29073 [R] KOG0594 Protein kinase PCTAIRE and related kinases 75 5e-13
CE20258 [R] KOG0593 Predicted protein kinase KKIAMRE 75 5e-13
CE18967 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD a... 75 5e-13
CE06779 [R] KOG0594 Protein kinase PCTAIRE and related kinases 75 5e-13
At1g63700 [T] KOG0198 MEKK and related serine/threonine protein ... 75 5e-13
7296166 [T] KOG0614 cGMP-dependent protein kinase 75 5e-13
YPL150w [T] KOG0583 Serine/threonine protein kinase 74 7e-13
Hs4506071 [T] KOG0695 Serine/threonine protein kinase 74 7e-13
Hs20986521 [T] KOG0665 Jun-N-terminal kinase (JNK) 74 7e-13
Hs20986519 [T] KOG0665 Jun-N-terminal kinase (JNK) 74 7e-13
Hs14110390 [D] KOG0600 Cdc2-related protein kinase 74 7e-13
Hs14110387 [D] KOG0600 Cdc2-related protein kinase 74 7e-13
CE28061 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 74 7e-13
CE28060 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 74 7e-13
CE28059 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 74 7e-13
CE28058 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 74 7e-13
CE28057 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 74 7e-13
CE28056 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 74 7e-13
CE28055 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 74 7e-13
CE28054 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 74 7e-13
CE28053 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 74 7e-13
CE28051 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 74 7e-13
At4g12020_6 [T] KOG0198 MEKK and related serine/threonine protei... 74 7e-13
YHR082c [T] KOG0583 Serine/threonine protein kinase 74 9e-13
SPAC2C4.14c [T] KOG0201 Serine/threonine protein kinase 74 9e-13
Hs7706549 [D] KOG0600 Cdc2-related protein kinase 74 9e-13
Hs4507281 [R] KOG0593 Predicted protein kinase KKIAMRE 74 9e-13
Hs4507273 [D] KOG0580 Serine/threonine protein kinase 74 9e-13
Hs20551615 [K] KOG0666 Cyclin C-dependent kinase CDK8 74 9e-13
Hs16418343 [T] KOG0583 Serine/threonine protein kinase 74 9e-13
Hs14754789 [OUT] KOG0595 Serine/threonine-protein kinase involve... 74 9e-13
CE29020 [T] KOG0660 Mitogen-activated protein kinase 74 9e-13
At4g11330 [T] KOG0660 Mitogen-activated protein kinase 74 9e-13
At2g45490 [D] KOG0580 Serine/threonine protein kinase 74 9e-13
7298087 [T] KOG0660 Mitogen-activated protein kinase 74 9e-13
7294265 [TR] KOG0606 Microtubule-associated serine/threonine kin... 74 9e-13
SPBC19C2.05 [T] KOG0583 Serine/threonine protein kinase 74 1e-12
Hs4826948 [T] KOG0616 cAMP-dependent protein kinase catalytic su... 74 1e-12
Hs4502745 [K] KOG0666 Cyclin C-dependent kinase CDK8 74 1e-12
ECU01g0630 [D] KOG0575 Polo-like serine/threonine protein kinase 74 1e-12
CE18699 [T] KOG0694 Serine/threonine protein kinase 74 1e-12
CE01146 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kin... 74 1e-12
At4g08470 [T] KOG0198 MEKK and related serine/threonine protein ... 74 1e-12
At3g10540 [T] KOG0592 3-phosphoinositide-dependent protein kinas... 74 1e-12
At2g42630 [T] KOG0192 Tyrosine kinase specific for activated (GT... 74 1e-12
CE07599 [T] KOG0576 Mitogen-activated protein kinase kinase kina... 73 1e-12
At3g08720 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 73 1e-12
YPL203w [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 73 2e-12
YNR047w [R] KOG0610 Putative serine/threonine protein kinase 73 2e-12
YDR523c [T] KOG0201 Serine/threonine protein kinase 73 2e-12
SPAC23H4.17c [K] KOG0666 Cyclin C-dependent kinase CDK8 73 2e-12
Hs7662210 [OUT] KOG0595 Serine/threonine-protein kinase involved... 73 2e-12
Hs5453860 [R] KOG0594 Protein kinase PCTAIRE and related kinases 73 2e-12
Hs15451902 [T] KOG0576 Mitogen-activated protein kinase kinase k... 73 2e-12
Hs15011928 [R] KOG0594 Protein kinase PCTAIRE and related kinases 73 2e-12
ECU03g0620 [D] KOG0590 Checkpoint kinase and related serine/thre... 73 2e-12
CE20493 [TR] KOG0606 Microtubule-associated serine/threonine kin... 73 2e-12
At4g32830 [D] KOG0580 Serine/threonine protein kinase 73 2e-12
At3g04530 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 73 2e-12
At1g45160 [TR] KOG0606 Microtubule-associated serine/threonine k... 73 2e-12
7297631 [T] KOG0665 Jun-N-terminal kinase (JNK) 73 2e-12
7296450 [D] KOG0575 Polo-like serine/threonine protein kinase 73 2e-12
7291043 [T] KOG0660 Mitogen-activated protein kinase 73 2e-12
SPACUNK12.02c [T] KOG0032 Ca2+/calmodulin-dependent protein kina... 72 2e-12
HsM20070143 [T] KOG0665 Jun-N-terminal kinase (JNK) 72 2e-12
Hs7706601 [T] KOG0192 Tyrosine kinase specific for activated (GT... 72 2e-12
Hs7706286 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase E... 72 2e-12
Hs21237739 [T] KOG0665 Jun-N-terminal kinase (JNK) 72 2e-12
Hs21237736 [T] KOG0665 Jun-N-terminal kinase (JNK) 72 2e-12
Hs19526767 [T] KOG0192 Tyrosine kinase specific for activated (G... 72 2e-12
Hs17461944 [R] KOG0593 Predicted protein kinase KKIAMRE 72 2e-12
Hs16950615 [Z] KOG0613 Projectin/twitchin and related proteins 72 2e-12
Hs16936530 [R] KOG0594 Protein kinase PCTAIRE and related kinases 72 2e-12
CE21239 [T] KOG0583 Serine/threonine protein kinase 72 2e-12
CE20717 [T] KOG0583 Serine/threonine protein kinase 72 2e-12
At1g10210 [T] KOG0660 Mitogen-activated protein kinase 72 2e-12
7300435 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and r... 72 2e-12
YPL042c [K] KOG0666 Cyclin C-dependent kinase CDK8 72 3e-12
Hs9966875 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 72 3e-12
Hs20547878 [R] KOG0589 Serine/threonine protein kinase 72 3e-12
Hs18602554 [T] KOG0578 p21-activated serine/threonine protein ki... 72 3e-12
7304311 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 72 3e-12
7300224 [T] KOG0201 Serine/threonine protein kinase 72 3e-12
7297611 [T] KOG0614 cGMP-dependent protein kinase 72 3e-12
Hs4506091 [T] KOG0660 Mitogen-activated protein kinase 72 4e-12
Hs21359873 [D] KOG0575 Polo-like serine/threonine protein kinase 72 4e-12
Hs20535816 [T] KOG0695 Serine/threonine protein kinase 72 4e-12
Hs14141724 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase ... 72 4e-12
Hs10864650 [T] KOG0695 Serine/threonine protein kinase 72 4e-12
CE26649 [D] KOG0575 Polo-like serine/threonine protein kinase 72 4e-12
CE18608 [R] KOG0594 Protein kinase PCTAIRE and related kinases 72 4e-12
Hs22050308_2 [T] KOG0198 MEKK and related serine/threonine prote... 72 4e-12
SPBC19F8.07 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polyme... 71 6e-12
Hs14776113 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 71 6e-12
CE08098 [T] KOG0612 Rho-associated coiled-coil containing protei... 71 6e-12
At4g01370 [T] KOG0660 Mitogen-activated protein kinase 71 6e-12
At2g37840 [OUT] KOG0595 Serine/threonine-protein kinase involved... 71 6e-12
At1g48490 [TR] KOG0606 Microtubule-associated serine/threonine k... 71 6e-12
At1g49180_1 [OUT] KOG0595 Serine/threonine-protein kinase involv... 71 6e-12
YBR160w [R] KOG0594 Protein kinase PCTAIRE and related kinases 71 7e-12
SPCC162.10 [RT] KOG0598 Ribosomal protein S6 kinase and related ... 71 7e-12
SPAC1805.01c [T] KOG1152 Signal transduction serine/threonine ki... 71 7e-12
Hs22035600 [T] KOG0576 Mitogen-activated protein kinase kinase k... 71 7e-12
Hs16950621 [Z] KOG0613 Projectin/twitchin and related proteins 71 7e-12
Hs16950613 [Z] KOG0613 Projectin/twitchin and related proteins 71 7e-12
Hs16950611 [Z] KOG0613 Projectin/twitchin and related proteins 71 7e-12
Hs16950601 [Z] KOG0613 Projectin/twitchin and related proteins 71 7e-12
CE19294 [T] KOG0198 MEKK and related serine/threonine protein ki... 71 7e-12
CE04603 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 71 7e-12
At2g31500 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 71 7e-12
At1g57700 [D] KOG0600 Cdc2-related protein kinase 71 7e-12
At1g54510 [R] KOG0589 Serine/threonine protein kinase 71 7e-12
7302908 [R] KOG0594 Protein kinase PCTAIRE and related kinases 71 7e-12
7300106 [T] KOG0690 Serine/threonine protein kinase 71 7e-12
YLR362w [T] KOG0198 MEKK and related serine/threonine protein ki... 70 9e-12
SPCC576.15c [T] KOG0592 3-phosphoinositide-dependent protein kin... 70 9e-12
SPBC8D2.19 [T] KOG0661 MAPK related serine/threonine protein kinase 70 9e-12
HsM4826916 [D] KOG0575 Polo-like serine/threonine protein kinase 70 9e-12
Hs15619015 [T] KOG0616 cAMP-dependent protein kinase catalytic s... 70 9e-12
CE27410 [T] KOG0583 Serine/threonine protein kinase 70 9e-12
CE01405 [T] KOG0577 Serine/threonine protein kinase 70 9e-12
At1g62400 [T] KOG0192 Tyrosine kinase specific for activated (GT... 70 9e-12
7304358 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 70 9e-12
>YNL183c [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 790
Score = 764 bits (1972), Expect = 0.0
Identities = 424/806 (52%), Positives = 497/806 (61%), Gaps = 55/806 (6%)
Query: 1 MSSLTKLLQEKRNQEPSSKSALTSS-------LKGSLAESRNSNSQSHAGHPNGTVVSSP 53
MSSLT+LLQEKR E S+ S TS+ SL + S SH G + + S
Sbjct: 1 MSSLTRLLQEKRKNETSNSSPRTSADTLTTTPESQSLDLHSRNKSSSHIGSVSNSSSSDR 60
Query: 54 MEIRDGAGGSDTTVTQVDSNDDGS------LEASYEFSQSFVNANSAHTATMYGSSVPNX 107
GS TTVTQ+ S +D S L+ +FS SF+NAN AHTA+ YG+S +
Sbjct: 61 NRANVPVPGSVTTVTQIYSEEDSSSTAGSSLDDRNQFSSSFLNANFAHTASFYGTSAQSR 120
Query: 108 XXXXXXXXXXXKFPQDTNGRGVPGRLGTSIGRHTTSTXXXXXXXXXXXXXXXXXXXXXXX 167
++G + I ++T
Sbjct: 121 DRFGSLINDQGTAGLSSHGGSFAAQ--NRITSRLSTTSHTSGRAIPSLSSSIPYSVPNSN 178
Query: 168 XXXXXXXXXXXXXXXXWLDKH-GSLPSNIAAIDSNVISSPKVESVEPRFVISKQKLQQKS 226
WL+ + G +P+NI+AIDSNVISSPKV+SVEPRFVISKQKLQ+ S
Sbjct: 179 KDNNSSNSNSSSLSSSWLETYAGGMPNNISAIDSNVISSPKVDSVEPRFVISKQKLQKAS 238
Query: 227 ----NMNHDTGKPVXXXXXXXXXXXXXXXXKNKDNEPSLVASSYGAGVXXXXXXXXXXXX 282
N N + + KN ++S AG+
Sbjct: 239 MDSNNANATQSRSISRSGSFSSQLGNFFFSKNSKES----SNSNSAGMSFSANSNGPSPN 294
Query: 283 XXXXXXXXXXXXXXXXXXXXXXXXXIPKPIRARASSIYNSSRQPTASYNEHVLGSPQSLH 342
IPKPIRAR SSIY++SRQPT SY ++ GSP S+H
Sbjct: 295 IKNPNVTNGSTP-------------IPKPIRARQSSIYSASRQPTGSYTDNFYGSPSSVH 341
Query: 343 ENLSQNQYTPKSRHSSVADLKRFFKKHGNXXXXXXXXX---------------XXXXXXX 387
++L +Q P+S+HSS+ DLKRFFKK N
Sbjct: 342 DHLPPSQSVPRSQHSSIGDLKRFFKKSSNSNLSSNSNNVIPNGSPLSSGIAVPSHSHSSS 401
Query: 388 XXXXXXXXXXXXXXXXNDVVYAASHVPA-LPFSKRYLKTGENLGAGAGGSVRLMKRISDN 446
D +Y+ SH + +PFSKRY+KTG +LGAGAGGSV+L +RISDN
Sbjct: 402 HFAAGNNSYSTSYNGNGDTIYSHSHGGSGIPFSKRYIKTGADLGAGAGGSVKLAQRISDN 461
Query: 447 QVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLRHPNIISTIEIVYENNRIFQVMEYCD 506
++FAVKEFR KFE+ESKRDYVKKITSEYCIGTTL HPNII TIEIVYEN+RI QVMEYC+
Sbjct: 462 KIFAVKEFRTKFENESKRDYVKKITSEYCIGTTLNHPNIIETIEIVYENDRILQVMEYCE 521
Query: 507 YDLFAIVMSNKMSYEEICCCFKQILTGVEYLHSIGLAHRDMKLDNCVINNQGIVKLIDFG 566
YDLFAIVMSNKMSYEEICCCFKQILTGV+YLHSIGLAHRD+KLDNCVIN +GIVKLIDFG
Sbjct: 522 YDLFAIVMSNKMSYEEICCCFKQILTGVQYLHSIGLAHRDLKLDNCVINEKGIVKLIDFG 581
Query: 567 AAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFTKYDPRPVDIWSVAILFACMVLKKFPW 626
AA VFSYP SK L+E+SGIVGSDPYLAPEVCIF KYDPRPVDIWS AI+FACM+LKKFPW
Sbjct: 582 AAVVFSYPFSKNLVEASGIVGSDPYLAPEVCIFAKYDPRPVDIWSSAIIFACMILKKFPW 641
Query: 627 KIPKLKDNSFKFFCSGRDCDSLSALVTKTPKPPSYDNAVQSDEPAESTSKSNNPSDPNNT 686
KIPKL+DNSFK FCSGRDCDSLS+LVT+TP PPSYD + S E + S SNN SDPNN
Sbjct: 642 KIPKLRDNSFKLFCSGRDCDSLSSLVTRTPDPPSYDES-HSTEKKKPESSSNNVSDPNNV 700
Query: 687 NIGPQRLLHSLPEETHHIIGRMVDLAPACRANIEEVLNDPWIQSIDMCTVEVDNQGNYVV 746
NIGPQRLLHSLPEET HI+GRM+DLAPACR NIEE++ DPWI+SIDMC + D VV
Sbjct: 701 NIGPQRLLHSLPEETQHIVGRMIDLAPACRGNIEEIMEDPWIRSIDMCHLVEDGLSFKVV 760
Query: 747 HPGMDHKHTQVDQSEAHIAGLEKKKK 772
G DH HTQVDQSEAHIAGLEKKKK
Sbjct: 761 R-GEDHHHTQVDQSEAHIAGLEKKKK 785
>YDL214c [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 699
Score = 372 bits (956), Expect = e-103
Identities = 178/355 (50%), Positives = 248/355 (69%), Gaps = 16/355 (4%)
Query: 419 SKRYLKTGENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGT 478
S++Y LG G+GG V+L++R+ DN+VFA+KE+R K + ES+R Y+K I SEYCI +
Sbjct: 357 SRKYRDLDVVLGEGSGGKVKLVQRVLDNKVFALKEYRSKKKRESERKYIKNIISEYCIAS 416
Query: 479 TLRHPNIISTIEIVYENNRIFQVMEYCDYDLFAIVMSNKMSYEEICCCFKQILTGVEYLH 538
TL++PNI T+EI+YE +IFQ++EYC+YDLF++VMS KM YEEICC FKQ++ GV+YLH
Sbjct: 417 TLKNPNICETLEILYEKGKIFQILEYCEYDLFSLVMSEKMHYEEICCLFKQLINGVKYLH 476
Query: 539 SIGLAHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCI 598
IGL+HRD+KLDNCV+ +GI+KLIDFGA+ VF YP S +IE++GIVGSDPYL+PEV
Sbjct: 477 DIGLSHRDLKLDNCVVTRRGILKLIDFGASSVFHYPLSSQMIEANGIVGSDPYLSPEVFY 536
Query: 599 FTKYDPRPVDIWSVAILFACMVLKKFPWKIPKLKDNSFKFFCSGRDCDSLSALVTKTPKP 658
F +YDPR +D+WSV I+F CM+ ++FPWK PK+KD FK FCSGR S LVT+
Sbjct: 537 FNEYDPRALDVWSVGIIFFCMITRRFPWKYPKVKDVQFKAFCSGRGVSSFKDLVTR---- 592
Query: 659 PSYDNAVQSDEPAESTSKSNNPSDPNNTNIGPQRLLHSLPEETHHIIGRMVDLAPACRAN 718
P+ D +S + N+ + ++GP +LH LPEETH I+ R+++++P R
Sbjct: 593 PATD---------DSNNYDNDGYEEGVIDMGPNFILHRLPEETHKIMRRILEVSPFRRIT 643
Query: 719 IEEVLNDPWIQSIDMCTV---EVDNQGNYVVHPGMDHKHTQVDQSEAHIAGLEKK 770
I +L D WI+ I+ C V N+ + + +H HT +DQ AHI GL ++
Sbjct: 644 INGILQDGWIKEIETCQVVGAASPNEASLRIINKGNHIHTNIDQRYAHIGGLHQR 698
>SPCC1020.10 [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 650
Score = 340 bits (873), Expect = 4e-93
Identities = 171/350 (48%), Positives = 228/350 (64%), Gaps = 12/350 (3%)
Query: 420 KRYLKTGENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTT 479
K+Y K G LG+GAGGSVR+MKR SD ++FAVKEFR + E++R+Y +K+T+E+CIG+
Sbjct: 299 KKYGKFGRMLGSGAGGSVRIMKRSSDGKIFAVKEFRARRPTETEREYARKVTAEFCIGSA 358
Query: 480 LRHPNIISTIEIVYENNRIFQVMEYCDYDLFAIVMSNKMSYEEICCCFKQILTGVEYLHS 539
L H NII T++IV EN + ++VMEY YD+F+IVMS KM+ E+ CCFKQ+L+GV YLHS
Sbjct: 359 LHHTNIIETLDIVEENKKFYEVMEYAPYDMFSIVMSGKMTMPEVYCCFKQLLSGVAYLHS 418
Query: 540 IGLAHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIF 599
+GLAHRD+KLDN V+++ VK+IDFG+A VF YP ++E++G+VGSDPYLAPE +
Sbjct: 419 MGLAHRDLKLDNLVVDSNCFVKIIDFGSAVVFKYPFEADIVEATGVVGSDPYLAPETLVR 478
Query: 600 TKYDPRPVDIWSVAILFACMVLKKFPWKIPKLKDNSFKFFC---SGRDCDSLSALVTKTP 656
YDPR VDIWS AI+F CM L++FPWK PKL DNSF+ FC D +S S ++
Sbjct: 479 KLYDPRAVDIWSSAIIFCCMALRRFPWKYPKLSDNSFRLFCMKQPSNDAESPSDILADIK 538
Query: 657 KPPSYDNAVQ----SDEPAESTSKSNNPSDPNNTNIGPQRLLHSLPEETHHIIGRMVDLA 712
K + + +DE SK++N S GP RLL LP ET +I M++L
Sbjct: 539 KQRLVEQGCEPIRKTDESHSPNSKTDNSSTHKQELYGPWRLLRLLPRETRAVIAHMLELD 598
Query: 713 PACRANIEEVLNDPWIQSIDMCTVEVDNQGNYVVHPGMDHKHTQVDQSEA 762
P R +I V D WI I MC +E V+H H H V E+
Sbjct: 599 PVKRYDIHRVFADNWINDISMCHME----NGKVIH-SPTHVHNLVASEES 643
>YDL025c [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 620
Score = 283 bits (723), Expect = 9e-76
Identities = 152/348 (43%), Positives = 207/348 (58%), Gaps = 46/348 (13%)
Query: 420 KRYLKTGENLGAGAGGSVRLMKRISDNQVFAVKEFR-PKFEHESKR-----DYVKKITSE 473
++Y G LG GA GSV +++R +D ++FA K FR P +E +Y KK+T+E
Sbjct: 299 EKYGIPGRKLGEGASGSVSVVER-TDGKLFACKMFRKPHLNNEGTNQSQLANYSKKVTTE 357
Query: 474 YCIGTTLRHPNIISTIEIVYENNRIFQVMEYCDYDLFAIVMSNKMSYEEICCCFKQILTG 533
+CIG+TL H NI+ T++++ E + VMEY YD F +VMSN M+ +E+ C FKQ+ G
Sbjct: 358 FCIGSTLHHENIVETLDMLTEGDTYLLVMEYAPYDFFNLVMSNLMTQDEVNCYFKQLCHG 417
Query: 534 VEYLHSIGLAHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLA 593
V YLHS+GLAHRD+KLDNCV+ GI+KLIDFG+A VF YP+ T+++S GIVGSDPYLA
Sbjct: 418 VNYLHSMGLAHRDLKLDNCVVTKDGILKLIDFGSAVVFQYPYEDTIVKSHGIVGSDPYLA 477
Query: 594 PEVCIFTKYDPRPVDIWSVAILFACMVLKKFPWKIPKLKDNSFKFFCSGRDCDSLSALVT 653
PE+ T YDPR D+WS+AI+F CMVLK+FPWK PK NSF+ F
Sbjct: 478 PELLKQTSYDPRVADVWSIAIIFYCMVLKRFPWKAPKKSFNSFRLF-------------- 523
Query: 654 KTPKPPSYDNAVQSDEPAESTSKSNNPSDPNNTNIGPQRLLHSLPEETHHIIGRMVDLAP 713
T +P D+ V+ GP ++L LP + IIGRM+ L P
Sbjct: 524 -TEEPEDEDDIVR----------------------GPNKILRLLPRHSRTIIGRMLALEP 560
Query: 714 ACRANIEEVLNDPWIQSIDMCTVEVDNQGNYVVHPGMDHKHTQVDQSE 761
R + +V+ D W+ S+ C EVD +V +HKH V + E
Sbjct: 561 KQRVLMNDVVKDDWLVSVPSC--EVDPTSGDLVEKPKNHKHHLVTEEE 606
>YOR267c [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 759
Score = 276 bits (705), Expect = 1e-73
Identities = 128/231 (55%), Positives = 176/231 (75%), Gaps = 3/231 (1%)
Query: 419 SKRYLKTGENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGT 478
+++Y K G+ LG+GAGGSV+++ R +D FAVKEFRP+ +ES ++Y KK T+E+CIG+
Sbjct: 211 AQKYGKLGKLLGSGAGGSVKVLVRPTDGATFAVKEFRPRKPNESVKEYAKKCTAEFCIGS 270
Query: 479 TLRHPNIISTIEIVYEN--NRIFQVMEYCDYDLFAIVMSNKMSYEEICCCFKQILTGVEY 536
TL HPN+I T+++ ++ N+ ++VMEYC D FA+VM+ KMS EI CC KQ+ GV+Y
Sbjct: 271 TLHHPNVIETVDVFSDSKQNKYYEVMEYCPIDFFAVVMTGKMSRGEINCCLKQLTEGVKY 330
Query: 537 LHSIGLAHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEV 596
LHS+GLAHRD+KLDNCV+ +QGI+KLIDFG+A VF YP + + GIVGSDPYLAPEV
Sbjct: 331 LHSMGLAHRDLKLDNCVMTSQGILKLIDFGSAVVFRYPFEDGVTMAHGIVGSDPYLAPEV 390
Query: 597 CIFTK-YDPRPVDIWSVAILFACMVLKKFPWKIPKLKDNSFKFFCSGRDCD 646
TK YDP+ VDIWS+ I++ CMVLK+FPWK P+ D++F+ +C D +
Sbjct: 391 ITSTKSYDPQCVDIWSIGIIYCCMVLKRFPWKAPRDSDDNFRLYCMPDDIE 441
Score = 57.8 bits (138), Expect = 6e-08
Identities = 34/105 (32%), Positives = 55/105 (52%), Gaps = 10/105 (9%)
Query: 666 QSDEPAESTSKSNNPSD----PNNTNI--GPQRLLHSLPEETHHIIGRMVDLAPACRANI 719
Q+ + A S + N S P++ I GP RLL LP + I+ R++ + P RA +
Sbjct: 654 QNQDKAHSIASDNKSSQQHRGPHHKKIIHGPYRLLRLLPHASRPIMSRILQVDPKKRATL 713
Query: 720 EEVLNDPWIQSIDMCTVEVDNQGNYVVHPGMDHKHTQVDQSEAHI 764
+++ ND W +I CT +D++ + PG H HT V + AH+
Sbjct: 714 DDIFNDEWFAAIAACT--MDSKNKVIRAPG--HHHTLVREENAHL 754
>SPAC22G7.08 [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 513
Score = 202 bits (515), Expect = 1e-51
Identities = 108/310 (34%), Positives = 159/310 (50%), Gaps = 41/310 (13%)
Query: 422 YLKTGENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLR 481
Y K +G GA +R++ + ++ K FRP + R YV+ +EY +TLR
Sbjct: 240 YGKLNNVIGEGASSFIRVINDRNKLPIYVAKVFRPPLDTSLLRRYVRYFIAEYTFASTLR 299
Query: 482 HPNIISTIEIVYENNRIFQVMEYCDYDLFAIVMSNKMSYEEICCCFKQILTGVEYLHSIG 541
HPNII ++I+Y+ + I Q++EY YDLF + S + F Q+L GV Y+HS+G
Sbjct: 300 HPNIIKVLDIIYKRHTILQIIEYVPYDLFTFITKGHCSALKADQMFFQLLDGVAYMHSLG 359
Query: 542 LAHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFTK 601
+AHRD+KLDN +++ VK+IDFG A VF YP T + S G+VGS PY+APEV
Sbjct: 360 IAHRDIKLDNIMLDENLNVKIIDFGTAFVFHYPFESTTLMSDGVVGSKPYVAPEVLTQKP 419
Query: 602 YDPRPVDIWSVAILFACMVLKKFPWKIPKLKDNSFKFFCSGRDCDSLSALVTKTPKPPSY 661
YDP VD+WS AI++ C+ LK+FPWK+P D F + + R
Sbjct: 420 YDPSAVDVWSCAIVYCCIALKRFPWKVPHTSDKRFNLYVTQR------------------ 461
Query: 662 DNAVQSDEPAESTSKSNNPSDPNNTNIGPQRLLHSLPEETHHIIGRMVDLAPACRANIEE 721
+DPN + +L+ SLP + I M+D+ R +I
Sbjct: 462 -------------------NDPNTKS----QLIESLPMNSRDTIYHMLDIDFNTRCSISG 498
Query: 722 VLNDPWIQSI 731
+ W+Q +
Sbjct: 499 ARSTTWMQQV 508
>YCR008w [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 603
Score = 167 bits (423), Expect = 6e-41
Identities = 102/328 (31%), Positives = 168/328 (51%), Gaps = 53/328 (16%)
Query: 418 FSKRYLKTGENLGAGAGGSVRLMKRIS--------DNQVFAVKEFRPKFEHESKRDYVKK 469
F+++Y + E LG GA G VR+ ++ + +++AVKEF+ + ES Y K+
Sbjct: 311 FAEKYGRCQEVLGKGAFGVVRICQKKNVSSQDGNKSEKLYAVKEFKRRTS-ESAEKYSKR 369
Query: 470 ITSEYCIGTTLRHPNIISTIEIVYE-NNRIFQVMEYC-DYDLFAIVMS-NKMSYEEICCC 526
+TSE+CI ++L H NI++T+++ + +VMEYC DLF +V++ K+ Y E C
Sbjct: 370 LTSEFCISSSLHHTNIVTTLDLFQDAKGEYCEVMEYCAGGDLFTLVVAAGKLEYMEADCF 429
Query: 527 FKQILTGVEYLHSIGLAHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIV 586
FKQ++ GV Y+H +G+ HRD+K +N ++ + G++K+ DFG +E F K + S G+
Sbjct: 430 FKQLIRGVVYMHEMGVCHRDLKPENLLLTHDGVLKITDFGNSECFKMAWEKNIHLSGGVC 489
Query: 587 GSDPYLAPEVCIFTKYDPRPVDIWSVAILFACMVLKKFPWKIPKLKDNSFKFFCSGRDCD 646
GS PY+APE I ++DPRPVDIW+ +++ M + W + D + + GR
Sbjct: 490 GSSPYIAPEEYIKEEFDPRPVDIWACGVIYMAMRTGRQLWSSAEKDDPFYMNYLKGR--- 546
Query: 647 SLSALVTKTPKPPSYDNAVQSDEPAESTSKSNNPSDPNNTNIGPQRLLHSLPEETHHIIG 706
+ Y EP ES ++ ++I
Sbjct: 547 ---------KEKGGY-------EPIESLKRA----------------------RCRNVIY 568
Query: 707 RMVDLAPACRANIEEVLNDPWIQSIDMC 734
M+D P R N +++LN W + I C
Sbjct: 569 SMLDPVPYRRINGKQILNSEWGREIKCC 596
>SPAC29A4.16 [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 636
Score = 160 bits (406), Expect = 5e-39
Identities = 81/227 (35%), Positives = 139/227 (60%), Gaps = 9/227 (3%)
Query: 418 FSKRYLKTGENLGAGAGGSVRLMKRISDNQ-----VFAVKEFRPKFEHESKRDYVKKITS 472
F ++Y + E +G GA G VR+ ++ ++AVKEFR K ES++ Y K++TS
Sbjct: 346 FVEKYGRCQEVIGRGAFGVVRIAHKVDPQNSGSETLYAVKEFRRK-PAESQKKYTKRLTS 404
Query: 473 EYCIGTTLRHPNIISTIEIVYENNRIF-QVMEYCDY-DLFAIVMS-NKMSYEEICCCFKQ 529
E+CI ++LRHPN+I T++++ + + +VME C DL+ ++M+ ++ E C FKQ
Sbjct: 405 EFCISSSLRHPNVIHTLDLIQDGKGDYCEVMELCSGGDLYTLIMAAGRLEPMEADCFFKQ 464
Query: 530 ILTGVEYLHSIGLAHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSD 589
++ GV+YLH +G+AHRD+K +N ++ G +K+ DFG E F K + G+ GS
Sbjct: 465 LMRGVDYLHDMGVAHRDLKPENLLLTVSGSLKITDFGNGECFRMAWEKEAHMTCGLCGSA 524
Query: 590 PYLAPEVCIFTKYDPRPVDIWSVAILFACMVLKKFPWKIPKLKDNSF 636
PY+APE +++DPR VD+W+ +++ M + W++ K ++ +
Sbjct: 525 PYIAPEEYTESEFDPRAVDVWACGVIYMAMRTGRHLWRVAKKSEDEY 571
>SPCC70.05c [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 781
Score = 142 bits (359), Expect = 1e-33
Identities = 101/354 (28%), Positives = 173/354 (48%), Gaps = 57/354 (16%)
Query: 408 YAASHVPALPFSKRYLKTGENLGAGAGGSVRLM-----KRISDNQVFAVKEFRPKFEHES 462
YA VP L + + +++G+GA +R++ K N FAVK +R K + E+
Sbjct: 431 YAKRVVPRLSAKYKLVDETKDMGSGATAVIRIVTLKNPKENEKNLRFAVKAYRRKADDET 490
Query: 463 KRDYVKKITSEYCIGTTLRHPNIISTIEIVYENNRIFQ--------VMEYCDY-DLFAIV 513
Y+ K+ SE+ + + HPN++ + ++ +++ IF VM++C DL +++
Sbjct: 491 DGQYIAKLASEWLVQCRMEHPNVVKSYDLCIDSH-IFPLYSDTWCAVMDFCPRGDLLSLI 549
Query: 514 MS--NKMSYEEICCCFKQILTGVEYLHSIGLAHRDMKLDNCVINNQGIVKLIDFGAAEVF 571
+++ ++ C KQIL G+ Y+HS G+AHRD+K +N +I+ G++++ DFGA +V
Sbjct: 550 EDRHDRLGKKDFECMIKQILRGLNYIHSQGIAHRDIKPENILISEYGVLRITDFGACDVL 609
Query: 572 SYPHSK-TLIESS--GIVGSDPYLAPEVCIFTKYDPRPVDIWSVAILFACMVLKKFPWKI 628
P T +ES GI GSDPY+APE+ Y+ D+WS AI+ C+ + +P++
Sbjct: 610 CNPGDDITAVESKSMGIFGSDPYMAPEILTPGSYNAFFADMWSTAIVLHCLYFRTYPFRK 669
Query: 629 PKLKDNSFKFFCSG-RD----CDSLSALVTKTPKPPSYDNAVQSDEPAESTSKSNNPSDP 683
D + +C R+ CD + ++KT Y V
Sbjct: 670 ASQNDQLYAKYCKAWREYNLICDVQNIRISKT---LPYFKPV------------------ 708
Query: 684 NNTNIGPQRLLHSLPEETHHIIGRMVDLAPACRANIEEVLNDPWIQSIDMCTVE 737
N+ + QRL L T R +E LN P++Q I+ C+V+
Sbjct: 709 NDLPMHMQRLFFCLANPT-----------AEQRITAQEALNLPFVQEIECCSVD 751
>YKL168c [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 734
Score = 132 bits (333), Expect = 2e-30
Identities = 78/242 (32%), Positives = 135/242 (55%), Gaps = 32/242 (13%)
Query: 429 LGAGAGGSVRLMKRISDNQ--------------VFAVKEFRPKFEHESKRDYVKKITSEY 474
+GAGA G V+L R+ + + +AVKE +PK + + ++ + KITSE+
Sbjct: 428 VGAGAYGEVKLCARLRNEKDSPPFETYHDSKYIYYAVKELKPKPDSDLEK-FCTKITSEF 486
Query: 475 CIGTTLRH---------PNIISTIEIVYENNRIFQVMEYCDY-DLFAIV-----MSNKMS 519
IG +L H PNI++ +I+ +++ +VME+C DL+ ++ + ++
Sbjct: 487 IIGHSLSHYHKNGKKPAPNILNVFDILEDSSSFIEVMEFCPAGDLYGMLVGKSKLKGRLH 546
Query: 520 YEEICCCFKQILTGVEYLHSIGLAHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTL 579
E C KQ+L GV+++H G+AH D+K +N + G++K+ DFG + VF + +
Sbjct: 547 PLEADCFMKQLLHGVKFMHDHGIAHCDLKPENILFYPHGLLKICDFGTSSVFQTAWERRV 606
Query: 580 IESSGIVGSDPYLAPEVCIFTK-YDPRPVDIWSVAILFACMVLKKFPWKI-PKLKDNSFK 637
GI+GS+PY+APE + + YDPR +D WS +++ M+L + WK+ + KD S+
Sbjct: 607 HAQKGIIGSEPYVAPEEFVDGEYYDPRLIDCWSCGVVYITMILGHYLWKVASREKDMSYD 666
Query: 638 FF 639
F
Sbjct: 667 EF 668
>YJL165c [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 855
Score = 130 bits (327), Expect = 8e-30
Identities = 91/290 (31%), Positives = 141/290 (48%), Gaps = 66/290 (22%)
Query: 417 PFSKRYLKTGENLGAGAGGSVRLMKRISDNQ--------------VFAVKEFRPKFEHES 462
P S++Y K+ +GAGA G V++ R + FAVKE +PK +
Sbjct: 497 PCSQKYGKSIGVVGAGAYGVVKICARCKTAKDVLPYSTYSNGKKLFFAVKELKPKPGDQI 556
Query: 463 KRDYVKKITSEYCIGTTLRHP-------------------------NIISTIEIVYENNR 497
+ + ++TSE+ IG +L HP NI+ ++++ +N
Sbjct: 557 DK-FCTRLTSEFIIGHSLSHPHFEANAMIAGNVSRTTPPKHVFNAPNILKILDLMEYSNS 615
Query: 498 IFQVMEYC-DYDLFAIVMSNKMSYE-----------------------EICCCFKQILTG 533
+VME+C DL++++ N +S E E C KQ+L G
Sbjct: 616 FVEVMEFCASGDLYSLLTRNNISNESNNGSSRLIQTVKEGSGSPLHPLEADCFMKQLLNG 675
Query: 534 VEYLHSIGLAHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLA 593
V+Y+H G+AH D+K +N + G++K+ DFG + VF K + SG +GS+PY+A
Sbjct: 676 VQYMHDHGIAHCDLKPENILFQPNGLLKICDFGTSSVFQTAWEKHVHFQSGAMGSEPYVA 735
Query: 594 PEVCI-FTKYDPRPVDIWSVAILFACMVLKKFPWKIP-KLKDNSFKFFCS 641
PE I +YDPR VD WS I++ MV+ ++ WKI KD+ FK F S
Sbjct: 736 PEEFIRDAEYDPRLVDCWSCGIVYCTMVMGQYLWKIAIPEKDSLFKSFLS 785
>SPBC21.07c [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 461
Score = 109 bits (272), Expect = 2e-23
Identities = 90/323 (27%), Positives = 147/323 (44%), Gaps = 37/323 (11%)
Query: 427 ENLGAGAGGSVRLMK---RISDNQVF-AVKEFRP-KFEHESKRDYVKKITSEYCIGTTLR 481
+++ GA +++++ +I+D +++ A K +R K H+ + + + E+ I L
Sbjct: 124 KSIAKGATSTIKVVTHRDKITDAKIYYAAKVYRKTKTSHKKRLNTMVYFLREWSIQPKLD 183
Query: 482 HPNIIS------TIEIVYENNRIF-QVMEYCDY-DLFAIVMSNKMSYEEICCCFKQILTG 533
HPNI+ T+ V+ + F V EYC DLF + ++ E+ CC KQIL
Sbjct: 184 HPNILKVICPCVTLTSVFNKSAGFCLVQEYCPQGDLFKQIEEKVLTLEDKCCYLKQILQA 243
Query: 534 VEYLHSIGLAHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIE-SSGIVGSDPYL 592
V YL S +AHRD+K +N +I G++KL DFG +E+ P I SG VGS YL
Sbjct: 244 VAYLQSQRIAHRDLKPENILIGRDGLLKLTDFGTSEIVGNPGDNESIRFVSGAVGSLAYL 303
Query: 593 APEVCIFTKYDPRPVDIWSVAILFACMVLKKFPWKIPKLKDNSFKFFCSGRDCDSLSALV 652
APE +Y D WS IL + FP+K D + + S ++
Sbjct: 304 APEAFHENEYCGLLADRWSCGILLKVLFTGYFPFKTSVKTDLYYSKYMS---------IL 354
Query: 653 TKTPKPPSYDNAVQSDEPAESTSKSNNPSDPNNTNIGPQRLLHSLPEETHHIIGRMVDLA 712
T T S D + E + I + L +PE II +++
Sbjct: 355 TDTCGISSTDESSFQTEVIK--------------QIPTLQPLRYIPEGAKKIILSLLNPD 400
Query: 713 PACRANIEEVLNDPWIQSIDMCT 735
R +++ +L W++ +D C+
Sbjct: 401 SQNRPSLDSILGTAWVRKLDCCS 423
>YJR059w [T] KOG0583 Serine/threonine protein kinase
Length = 818
Score = 105 bits (262), Expect = 3e-22
Identities = 84/337 (24%), Positives = 146/337 (42%), Gaps = 48/337 (14%)
Query: 429 LGAGAGGSVRLMKR-ISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLRHP-NII 486
+G+G VR +K V+A+K+ + HES + K+ + E+ I L H +I
Sbjct: 261 IGSGGSSEVRKVKSSYRQKDVYALKKLNMIY-HESPEKFYKRCSKEFIIAKHLSHNVHIT 319
Query: 487 STIEIV------YENNRIFQVMEYCDYDLFAIVMSN---KMSYEEICCCFKQILTGVEYL 537
+T ++ Y +ME DLF ++ + + E C FKQ+ G+++
Sbjct: 320 NTFYLLKVPTTTYTTRGWGFIMELGVKDLFQLMERTGWKNVPFNEKYCLFKQVAQGIKFC 379
Query: 538 HSIGLAHRDMKLDNCVINNQGIVKLIDFGAAE---VFSYPHSKTLIESSGIVGSDPYLAP 594
H G+AHRD+K +N +I+ +GI KL DFG ++ V + ++ + G++GS PY P
Sbjct: 380 HDNGIAHRDLKPENVLISKEGICKLTDFGISDWYHVIPHDYTSPVKTCQGMIGSPPYTPP 439
Query: 595 EVCIF-----------TKYDPRPVDIWSVAILFACMVLKKFPWKIPKLKDNSFKFFCSGR 643
EV F Y+P +D +++ I+ M+ P+ D F+ F
Sbjct: 440 EVMYFDAKKHYPEKFQKPYNPLAMDSYALGIMLITMINNIIPFIDSCNTDARFREF---- 495
Query: 644 DCDSLSALVTKTPKPPSYDNAVQSDEPAESTSKSNNPSDPNNTNIGPQRLLHSLPEETHH 703
SYDN + P + P + ++ + +
Sbjct: 496 --------------EVSYDNFINHQNPHFRDKGCHKPGPGSEYSLA----RNFKNTDATR 537
Query: 704 IIGRMVDLAPACRANIEEVLNDPWIQSIDMCTVEVDN 740
I R+ D PA R ++++ NDP+ Q I+ C D+
Sbjct: 538 IAWRLADPNPATRYTMDDLFNDPFFQQIETCVEPNDD 574
>CE21879 [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 328
Score = 103 bits (257), Expect = 1e-21
Identities = 61/210 (29%), Positives = 112/210 (53%), Gaps = 8/210 (3%)
Query: 427 ENLGAGAGGSVRLMKRISDNQV-FAVKEFRPKFEHESKRDYVKKITSEYCIGTTLRHPNI 485
+++G GA G V L +++++ ++ A+K+ + ++++++I EY I ++H NI
Sbjct: 10 KSIGKGAFGQVFLAEKLNNPRIKVAMKKINI---FGAPKEFLEQIQQEYYIQKNMKHKNI 66
Query: 486 ISTIEIVYENNRIFQVMEYCDY-DLFA-IVMSNKMSYEEICCCFKQILTGVEYLHSIGLA 543
+ + + + E+ DLF I N M ++ KQ+++G++Y+H G+
Sbjct: 67 VKMYGMSMDTEFCYLFQEFVTGGDLFEKIDFENGMPVNQVKGYLKQLMSGLKYIHGCGIV 126
Query: 544 HRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFTKYD 603
HRD+K DN +IN+ +K+ DFG + F + L+ +G+ P++APE+ K+
Sbjct: 127 HRDIKPDNLLINSSDALKIADFGLSTRFIVDDKEILLHER--IGTTPFMAPELFAKKKHR 184
Query: 604 PRPVDIWSVAILFACMVLKKFPWKIPKLKD 633
PVDIWS IL ++ PW PK D
Sbjct: 185 GPPVDIWSAGILVFSLLTGNLPWDEPKESD 214
>Hs4502803 [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 476
Score = 103 bits (256), Expect = 1e-21
Identities = 66/205 (32%), Positives = 102/205 (49%), Gaps = 8/205 (3%)
Query: 427 ENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLRHPNII 486
+ LG GA G V+L + AVK K D + I E CI L H N++
Sbjct: 13 QTLGEGAYGEVQLAVNRVTEEAVAVKIVDMK----RAVDCPENIKKEICINKMLNHENVV 68
Query: 487 STIEIVYENNRIFQVMEYCDY-DLFAIVMSN-KMSYEEICCCFKQILTGVEYLHSIGLAH 544
E N + +EYC +LF + + M + F Q++ GV YLH IG+ H
Sbjct: 69 KFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLMAGVVYLHGIGITH 128
Query: 545 RDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFTKYDP 604
RD+K +N +++ + +K+ DFG A VF Y + + L+ + G+ PY+APE+ ++
Sbjct: 129 RDIKPENLLLDERDNLKISDFGLATVFRYNNRERLLNK--MCGTLPYVAPELLKRREFHA 186
Query: 605 RPVDIWSVAILFACMVLKKFPWKIP 629
PVD+WS I+ M+ + PW P
Sbjct: 187 EPVDVWSCGIVLTAMLAGELPWDQP 211
>At4g33950 [T] KOG0583 Serine/threonine protein kinase
Length = 357
Score = 100 bits (248), Expect = 1e-20
Identities = 69/228 (30%), Positives = 121/228 (52%), Gaps = 20/228 (8%)
Query: 413 VPALPFSKRYLKTGENLGAGAGGSVRLMKRISDNQVFAVK--EFRPKFEHESKRDYVKKI 470
+P + S RY + +++G+G G RLM+ N++ AVK E K + KR+ +
Sbjct: 12 LPIMHDSDRY-ELVKDIGSGNFGVARLMRDKQSNELVAVKYIERGEKIDENVKREIINH- 69
Query: 471 TSEYCIGTTLRHPNIISTIEIVYENNRIFQVMEYCDY-DLFA-IVMSNKMSYEEICCCFK 528
+LRHPNI+ E++ + VMEY +LF I + + S +E F+
Sbjct: 70 -------RSLRHPNIVRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQ 122
Query: 529 QILTGVEYLHSIGLAHRDMKLDNCVINNQGI--VKLIDFGAAEVFSYPHSKTLIESSGIV 586
Q+++GV Y H++ + HRD+KL+N +++ +K+ DFG ++ S HS + V
Sbjct: 123 QLISGVSYCHAMQVCHRDLKLENTLLDGSPAPRLKICDFGYSKS-SVLHS----QPKSTV 177
Query: 587 GSDPYLAPEVCIFTKYDPRPVDIWSVAILFACMVLKKFPWKIPKLKDN 634
G+ Y+APEV + +YD + D+WS + M++ +P++ P+ N
Sbjct: 178 GTPAYIAPEVLLKKEYDGKVADVWSCGVTLYVMLVGAYPFEDPEEPKN 225
>CE21086 [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 637
Score = 99.8 bits (247), Expect = 1e-20
Identities = 67/220 (30%), Positives = 110/220 (49%), Gaps = 5/220 (2%)
Query: 427 ENLGAGAGGSVRLMKRI-SDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLRHPNI 485
ENLG G+ V L+ ++ + N++FA+KE + E + +K+ S + RH N+
Sbjct: 22 ENLGEGSFAEVVLVAKVGTPNKMFAMKEISIVGKDECFMESIKRECSIQKRLSKSRHLNM 81
Query: 486 ISTIEIVYENNRIFQVMEYCDY-DLFA-IVMSNKMSYEEICCCFKQILTGVEYLHSIGLA 543
I EI ++ Y D DLF I + +E FKQ++ G+ ++H G+
Sbjct: 82 IHLFEIRTNPENYQLILSYADGGDLFEKINQHGGLGSDEAHRYFKQLIDGLRFIHEEGVT 141
Query: 544 HRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFTKYD 603
HRD+K +N ++ GI+K+ DFG A + + ++ ++ + GS PY+APEV Y
Sbjct: 142 HRDIKPENLLLTKSGILKIADFGFATMHRFNGAEQML--NAYCGSPPYIAPEVLTGIDYR 199
Query: 604 PRPVDIWSVAILFACMVLKKFPWKIPKLKDNSFKFFCSGR 643
VDIWS ++ M+ PW+ D +CS R
Sbjct: 200 GPAVDIWSAGVVLIAMIAGAVPWEQADHFDIFQSRYCSFR 239
Score = 98.6 bits (244), Expect = 3e-20
Identities = 74/254 (29%), Positives = 126/254 (49%), Gaps = 16/254 (6%)
Query: 405 DVVYAASHVP--ALPFSK--RYLKTGENLGAGAGGSVRLMKRISDNQV-FAVKEFRPKFE 459
+VV S +P + P S+ + K E+L G+ G V L + + V AVKE +
Sbjct: 321 NVVLTMSAIPITSTPTSRPRKEYKVVEHLCKGSFGQVHLCELTRNPSVKVAVKEVAVSGK 380
Query: 460 HESKRDYVKKITSEYCIGTTLRHPNIISTIEIVYENNRIFQVMEYCDY-DLF-AIVMSNK 517
V+K + + + H N+I ++++ VMEY D DLF + K
Sbjct: 381 SRKNLTAVQKEYKIHRRLSKIGHENVIQMMKMIETPKFYSLVMEYADGGDLFDELKEQEK 440
Query: 518 MSYEEICCCFKQILTGVEYLHSIGLAHRDMKLDNCVI------NNQGIVKLIDFGAAEVF 571
S ++ FKQ++ G++++H G+ HRD+KL+N ++ ++ G +K+ DFG A +
Sbjct: 441 FSRKDAHSYFKQLIKGLKFIHEQGIVHRDIKLENLLLVYSESEDDPGTLKITDFGLATKY 500
Query: 572 SYPHSKTLIESSGIVGSDPYLAPEVCIFTKYDPRPVDIWSVAILFACMVLKKFPWKIP-K 630
+ ++ GS PY APEVC Y PVDIWS ++ M++ + WK+ K
Sbjct: 501 RKDGEEIMLSED--CGSKPYAAPEVCTGNDYRGPPVDIWSAGVVLMTMLVGEHSWKVANK 558
Query: 631 LKDNSFKFFCSGRD 644
KD ++ + + +D
Sbjct: 559 EKDAAYSNWINAKD 572
>YDR477w [T] KOG0583 Serine/threonine protein kinase
Length = 633
Score = 99.4 bits (246), Expect = 2e-20
Identities = 68/212 (32%), Positives = 107/212 (50%), Gaps = 11/212 (5%)
Query: 427 ENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLRHPNII 486
+ LG G+ G V+L + Q A+K K +K D +I E LRHP+II
Sbjct: 59 KTLGEGSFGKVKLAYHTTTGQKVALKIINKKVL--AKSDMQGRIEREISYLRLLRHPHII 116
Query: 487 STIEIVYENNRIFQVMEYCDYDLFA-IVMSNKMSYEEICCCFKQILTGVEYLHSIGLAHR 545
+++ + I V+EY +LF IV +KMS +E F+QI++ VEY H + HR
Sbjct: 117 KLYDVIKSKDEIIMVIEYAGNELFDYIVQRDKMSEQEARRFFQQIISAVEYCHRHKIVHR 176
Query: 546 DMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFTKYDPR 605
D+K +N +++ VK+ DFG + + + +++S GS Y APEV Y
Sbjct: 177 DLKPENLLLDEHLNVKIADFGLSNIMT---DGNFLKTS--CGSPNYAAPEVISGKLYAGP 231
Query: 606 PVDIWSVAILFACMVLKKFPW---KIPKLKDN 634
VD+WS ++ M+ ++ P+ IP L N
Sbjct: 232 EVDVWSCGVILYVMLCRRLPFDDESIPVLFKN 263
>Hs4557439 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 305
Score = 99.4 bits (246), Expect = 2e-20
Identities = 81/307 (26%), Positives = 134/307 (43%), Gaps = 29/307 (9%)
Query: 427 ENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLRHPNII 486
E +G G G V K Q+ A+K+ R E E + E + L+HPNI+
Sbjct: 8 EKIGEGTYGVVYKAKNRETGQLVALKKIRLDLEMEGVPSTAIR---EISLLKELKHPNIV 64
Query: 487 STIEIVYENNRIFQVMEYCDYDLFAIVMS---NKMSYEEICCCFKQILTGVEYLHSIGLA 543
+++V+ +++ V E+ DL + S +++ I Q+L GV + HS +
Sbjct: 65 RLLDVVHNERKLYLVFEFLSQDLKKYMDSTPGSELPLHLIKSYLFQLLQGVSFCHSHRVI 124
Query: 544 HRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFTKYD 603
HRD+K N +IN G +KL DFG A F P L + V + Y APE+ + +K+
Sbjct: 125 HRDLKPQNLLINELGAIKLADFGLARAFGVP----LRTYTHEVVTLWYRAPEILLGSKFY 180
Query: 604 PRPVDIWSVAILFACMVLKKFPWKIPKLKDNSFKFFCSGRDCDSLSALVTKTPKPPSYDN 663
VDIWS+ +FA MV +K + D F+ F + TP ++
Sbjct: 181 TTAVDIWSIGCIFAEMVTRKALFPGDSEIDQLFRIF-----------RMLGTPSEDTWPG 229
Query: 664 AVQSDEPAESTSKSNNPSDPNNTNIGPQRLLHSLPEETHHIIGRMVDLAPACRANIEEVL 723
Q + S P T G + ++ +L E ++ +++ P+ R + L
Sbjct: 230 VTQLPD--------YKGSFPKWTRKGLEEIVPNLEPEGRDLLMQLLQYDPSQRITAKTAL 281
Query: 724 NDPWIQS 730
P+ S
Sbjct: 282 AHPYFSS 288
>CE26422 [D] KOG0600 Cdc2-related protein kinase
Length = 684
Score = 99.0 bits (245), Expect = 2e-20
Identities = 83/325 (25%), Positives = 153/325 (46%), Gaps = 39/325 (12%)
Query: 427 ENLGAGAGGSV-RLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLRHPNI 485
+ +G G G V + + ++ QV A+K R + E+E K + E I L H NI
Sbjct: 315 DQIGEGTYGQVYKAVNNLTGEQV-ALK--RVRLENE-KEGFPITAIREIKILRQLHHKNI 370
Query: 486 ISTIEIVYEN----------NRIFQVMEYCDYDLFAIVMSNKM---SYEEICCCFKQILT 532
+ ++IV ++ + V EY D+DL ++ S ++ + ++IC FKQ+L
Sbjct: 371 VRLMDIVIDDISMDELKRTRANFYLVFEYVDHDLIGLLESKELVDFNKDQICSLFKQLLE 430
Query: 533 GVEYLHSIGLAHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYL 592
G+ Y+H+ G HRD+K N ++NN+G +K+ D G A ++ ++ + ++ ++ + Y
Sbjct: 431 GLAYIHNTGFLHRDIKCSNILVNNKGELKIADLGLARLW---EKESRLYTNRVI-TLWYR 486
Query: 593 APEVCIFTKYDPRPVDIWSVAILFACMVLKKFPWKIPKLKDNSFKFFCSGRDCDSLSALV 652
PE+ + + +D+WS CM+ + F K +N F L+
Sbjct: 487 PPELLLGDERYGPAIDVWST----GCMLGELFTRKPLFNGNNEF----------GQLELI 532
Query: 653 TKTPKPPSYDNAVQSDEPAESTSKSNNPSDPNNTNIGPQRLLHSLPEETHHIIGRMVDLA 712
+K P+ DN + E + + + H +P E ++ +M+ L
Sbjct: 533 SKVCGSPNVDNWPELTELVGWNTFRMKRTYQRRIR---EEFEHIMPREAVDLLDKMLTLN 589
Query: 713 PACRANIEEVLNDPWIQSIDMCTVE 737
P R + +E LN PWI+S++ TV+
Sbjct: 590 PEKRISAKEALNHPWIRSLEHTTVQ 614
>CE20636 [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 687
Score = 98.6 bits (244), Expect = 3e-20
Identities = 64/205 (31%), Positives = 103/205 (50%), Gaps = 10/205 (4%)
Query: 429 LGAGAGGSVRLMKRIS-DNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLR---HPN 484
LG G G V L++ S + A+KE EH + + EY + L H N
Sbjct: 337 LGKGTFGKVLLIELESLPGEAVAMKEIEASGEHVEQ--ITLNVKKEYILTKRLSAPGHEN 394
Query: 485 IISTIEIVYENNRIFQVMEYCDY-DLFAIVMSN-KMSYEEICCCFKQILTGVEYLHSIGL 542
+I + I F +MEY D DLF + S +++ + FKQ++ G+ Y+HS G+
Sbjct: 395 VIRFLSIRTMPEHYFLIMEYADGGDLFDKISSEYRLTSSQAHGYFKQLIAGLRYIHSKGV 454
Query: 543 AHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFTKY 602
HRD+K +N ++ G++K+ DFG + ++L+++ G+ Y APEV + +Y
Sbjct: 455 THRDIKPENLMLTKAGVLKITDFGLGTLHIIKGEESLMDTR--CGTPQYAAPEVLVGNQY 512
Query: 603 DPRPVDIWSVAILFACMVLKKFPWK 627
PVDIWS ++ M+ PWK
Sbjct: 513 RGPPVDIWSAGVVLINMLTGHSPWK 537
Score = 81.3 bits (199), Expect = 5e-15
Identities = 62/218 (28%), Positives = 102/218 (46%), Gaps = 18/218 (8%)
Query: 429 LGAGAGGSVRLMKRISDNQV-FAVKEFRPKFEHESKRDYVKKITSEYCIGTTLR----HP 483
L G G V L + + V AVK+ + E +V+ I +E+ I L H
Sbjct: 27 LSEGTYGQVSLYESSKNPDVKIAVKQISTAGQSER---FVEHIKTEFAIHKGLSKIGGHR 83
Query: 484 NIISTIEIVYENNRIFQVMEYCDY-DLFAIVMSNKMSYEEIC-CCFKQILTGVEYLHSIG 541
N+IS +E+ ++ + EY D DLF + + Y E C FKQ+++G++++H
Sbjct: 84 NVISMMEMRKGSDCYTLLKEYADGGDLFKKLETEGEQYSENAQCFFKQLISGLKFIHEHE 143
Query: 542 LAHRDMKLDNCVINNQ------GIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPE 595
+ HRD+KL+N ++ +K+ DFG A + + ++ + GS PY APE
Sbjct: 144 IVHRDIKLENLLLMKSKSNLVPDTLKIADFGLATEYMVDGEELMLVDN--CGSPPYAAPE 201
Query: 596 VCIFTKYDPRPVDIWSVAILFACMVLKKFPWKIPKLKD 633
V + P D+WS ++ M+ PW KD
Sbjct: 202 VYSKQGHRGPPTDVWSSGVILMAMLTAGLPWDCAHRKD 239
>CE27768 [R] KOG0586 Serine/threonine protein kinase
Length = 1096
Score = 97.1 bits (240), Expect = 9e-20
Identities = 70/256 (27%), Positives = 118/256 (45%), Gaps = 28/256 (10%)
Query: 427 ENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLRHPNII 486
+ +G G V+L K + A+K + S ++K+ E I L HPNI+
Sbjct: 126 KTIGKGNFAKVKLAKHVITGHEVAIKIIDKTALNPSS---LQKLFREVKIMKQLDHPNIV 182
Query: 487 STIEIVYENNRIFQVMEYC------DYDLFAIVMSNKMSYEEICCCFKQILTGVEYLHSI 540
+++ ++ V+EY DY +V +M +E F+QI++ V+YLHS
Sbjct: 183 KLYQVMETEQTLYLVLEYASGGEVFDY----LVAHGRMKEKEARAKFRQIVSAVQYLHSK 238
Query: 541 GLAHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFT 600
+ HRD+K +N +++ +K+ DFG + FS + + GS PY APE+
Sbjct: 239 NIIHRDLKAENLLLDQDMNIKIADFGFSNTFSLGN-----KLDTFCGSPPYAAPELFSGK 293
Query: 601 KYDPRPVDIWSVAILFACMVLKKFPWKIPKLKDNSFKF--------FCSGRDCDSL--SA 650
KYD VD+WS+ ++ +V P+ LK+ + F DC++L
Sbjct: 294 KYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKF 353
Query: 651 LVTKTPKPPSYDNAVQ 666
LV + S DN ++
Sbjct: 354 LVINPQRRSSLDNIMK 369
>CE23838 [R] KOG0586 Serine/threonine protein kinase
Length = 1192
Score = 97.1 bits (240), Expect = 9e-20
Identities = 70/256 (27%), Positives = 118/256 (45%), Gaps = 28/256 (10%)
Query: 427 ENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLRHPNII 486
+ +G G V+L K + A+K + S ++K+ E I L HPNI+
Sbjct: 174 KTIGKGNFAKVKLAKHVITGHEVAIKIIDKTALNPSS---LQKLFREVKIMKQLDHPNIV 230
Query: 487 STIEIVYENNRIFQVMEYC------DYDLFAIVMSNKMSYEEICCCFKQILTGVEYLHSI 540
+++ ++ V+EY DY +V +M +E F+QI++ V+YLHS
Sbjct: 231 KLYQVMETEQTLYLVLEYASGGEVFDY----LVAHGRMKEKEARAKFRQIVSAVQYLHSK 286
Query: 541 GLAHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFT 600
+ HRD+K +N +++ +K+ DFG + FS + + GS PY APE+
Sbjct: 287 NIIHRDLKAENLLLDQDMNIKIADFGFSNTFSLGN-----KLDTFCGSPPYAAPELFSGK 341
Query: 601 KYDPRPVDIWSVAILFACMVLKKFPWKIPKLKDNSFKF--------FCSGRDCDSL--SA 650
KYD VD+WS+ ++ +V P+ LK+ + F DC++L
Sbjct: 342 KYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKF 401
Query: 651 LVTKTPKPPSYDNAVQ 666
LV + S DN ++
Sbjct: 402 LVINPQRRSSLDNIMK 417
>YCL024w [T] KOG0583 Serine/threonine protein kinase
Length = 1037
Score = 96.7 bits (239), Expect = 1e-19
Identities = 61/211 (28%), Positives = 108/211 (50%), Gaps = 13/211 (6%)
Query: 424 KTGENLGAGAGGSVRLMKRISDNQVFAVKE-----FRPKFEHESKRDYVK-KITSEYCIG 477
K GE LG G+ G V+L + AVK F H + + I E I
Sbjct: 22 KLGETLGFGSTGKVQLAQHERTGHRTAVKVISKSIFNNNGNHSNDDSVLPYNIEREIVIM 81
Query: 478 TTLRHPNIISTIEIVYENNRIFQVMEYCDY-DLFAIVMSN-KMSYEEICCCFKQILTGVE 535
L HPN++S ++ NN ++ ++EY + +LF +++ + + E CF+QI+ G+
Sbjct: 82 KLLSHPNVLSLYDVWETNNNLYLILEYAEKGELFNLLVDHGPLPEREAINCFRQIIIGIS 141
Query: 536 YLHSIGLAHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPE 595
Y H++G+ HRD+K +N ++++ +K+ DFG A + + L+E+S GS Y APE
Sbjct: 142 YCHALGIVHRDLKPENLLLDSFYNIKIADFGMAALQT---DADLLETS--CGSPHYAAPE 196
Query: 596 VCIFTKYDPRPVDIWSVAILFACMVLKKFPW 626
+ Y+ D+WS ++ ++ + P+
Sbjct: 197 IVSGLPYEGFASDVWSCGVILFALLTGRLPF 227
>At5g66880 [T] KOG0583 Serine/threonine protein kinase
Length = 361
Score = 96.3 bits (238), Expect = 2e-19
Identities = 88/341 (25%), Positives = 152/341 (43%), Gaps = 59/341 (17%)
Query: 413 VPALPFSKRYLKTGENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITS 472
+P + S RY +++G+G G RLM+ ++ AVK E K D + +
Sbjct: 13 MPIMHDSDRY-DFVKDIGSGNFGVARLMRDKLTKELVAVKYI----ERGDKID--ENVQR 65
Query: 473 EYCIGTTLRHPNIISTIEIVYENNRIFQVMEYCDY-DLFA-IVMSNKMSYEEICCCFKQI 530
E +LRHPNI+ E++ + +MEY +L+ I + + S +E F+Q+
Sbjct: 66 EIINHRSLRHPNIVRFKEVILTPTHLAIIMEYASGGELYERICNAGRFSEDEARFFFQQL 125
Query: 531 LTGVEYLHSIGLAHRDMKLDNCVINNQGI--VKLIDFGAAEVFSYPHSKTLIESSGIVGS 588
L+GV Y HS+ + HRD+KL+N +++ +K+ DFG ++ S HS + VG+
Sbjct: 126 LSGVSYCHSMQICHRDLKLENTLLDGSPAPRLKICDFGYSK-SSVLHS----QPKSTVGT 180
Query: 589 DPYLAPEVCIFTKYDPRPVDIWSVAILFACMVLKKFPWKIPKLKDNSFKFFCSGRDCDSL 648
Y+APEV + +YD + D+WS + M++ +P++ P+
Sbjct: 181 PAYIAPEVLLRQEYDGKIADVWSCGVTLYVMLVGAYPFEDPE------------------ 222
Query: 649 SALVTKTPKPPSYDNAVQSDEPAESTSKSNNPSDPNNTNIGPQRLLHSLPEETHHIIGRM 708
+P Y +Q S S P++ I P E H+I R+
Sbjct: 223 --------EPRDYRKTIQ-------RILSVKYSIPDDIRISP---------ECCHLISRI 258
Query: 709 VDLAPACRANIEEVLNDPW-IQSIDMCTVEVDNQGNYVVHP 748
PA R +I E+ W ++++ + N G+ P
Sbjct: 259 FVADPATRISIPEIKTHSWFLKNLPADLMNESNTGSQFQEP 299
>Hs20562757 [T] KOG0660 Mitogen-activated protein kinase
Length = 379
Score = 95.9 bits (237), Expect = 2e-19
Identities = 82/310 (26%), Positives = 137/310 (43%), Gaps = 35/310 (11%)
Query: 429 LGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLRHPNIIST 488
+G GA G V A+K+ P FEH++ Y ++ E I RH N+I
Sbjct: 48 IGEGAYGMVSSAYDHVRKTRVAIKKISP-FEHQT---YCQRTLREIQILLRFRHENVIGI 103
Query: 489 IEIVYENNR-----IFQVMEYCDYDLFAIVMSNKMSYEEICCCFKQILTGVEYLHSIGLA 543
+I+ + ++ V + + DL+ ++ S ++S + IC QIL G++Y+HS +
Sbjct: 104 RDILRASTLEAMRDVYIVQDLMETDLYKLLKSQQLSNDHICYFLYQILRGLKYIHSANVL 163
Query: 544 HRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFTKYD 603
HRD+K N +IN +K+ DFG A + H T + V + Y APE+ + +K
Sbjct: 164 HRDLKPSNLLINTTCDLKICDFGLARIADPEHDHTGFLTE-YVATRWYRAPEIMLNSKGY 222
Query: 604 PRPVDIWSVAILFACMVLKK--FPWKIPKLKDNSFKFFCSGRDCDSLSALVTKTPKPPSY 661
+ +DIWSV + A M+ + FP K D L+ ++ P
Sbjct: 223 TKSIDIWSVGCILAEMLSNRPIFPGK---------------HYLDQLNHILGILGSPS-- 265
Query: 662 DNAVQSDEPAESTSKSNN--PSDPNNTNIGPQRLLHSLPEETHHIIGRMVDLAPACRANI 719
Q D K+ N S P+ T + +L + ++ RM+ P R +
Sbjct: 266 ----QEDLNCIINMKARNYLQSLPSKTKVAWAKLFPKSDSKALDLLDRMLTFNPNKRITV 321
Query: 720 EEVLNDPWIQ 729
EE L P+++
Sbjct: 322 EEALAHPYLE 331
>At5g08590 [T] KOG0583 Serine/threonine protein kinase
Length = 353
Score = 95.9 bits (237), Expect = 2e-19
Identities = 77/305 (25%), Positives = 135/305 (44%), Gaps = 57/305 (18%)
Query: 427 ENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLRHPNII 486
++LGAG G RL++ ++ A+K E R + + E +L+HPNII
Sbjct: 8 KDLGAGNFGVARLLRHKDTKELVAMKYI------ERGRKIDENVAREIINHRSLKHPNII 61
Query: 487 STIEIVYENNRIFQVMEYCDY-DLF-AIVMSNKMSYEEICCCFKQILTGVEYLHSIGLAH 544
E++ + VMEY +LF I + + S E F+Q++ GV+Y HS+ + H
Sbjct: 62 RFKEVILTPTHLAIVMEYASGGELFDRICTAGRFSEAEARYFFQQLICGVDYCHSLQICH 121
Query: 545 RDMKLDNCVINNQ--GIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFTKY 602
RD+KL+N +++ ++K+ DFG ++ S HS+ VG+ Y+APEV +Y
Sbjct: 122 RDLKLENTLLDGSPAPLLKICDFGYSK-SSILHSR----PKSTVGTPAYIAPEVLSRREY 176
Query: 603 DPRPVDIWSVAILFACMVLKKFPWKIPKLKDNSFKFFCSGRDCDSLSALVTKTPKPPSYD 662
D + D+WS + M++ +P++ P N K ++ ++ K P Y
Sbjct: 177 DGKHADVWSCGVTLYVMLVGAYPFEDPNDPKNFRK---------TIQRIMAVQYKIPDYV 227
Query: 663 NAVQSDEPAESTSKSNNPSDPNNTNIGPQRLLHSLPEETHHIIGRMVDLAPACRANIEEV 722
+ + +E H++ R+ A R ++E+
Sbjct: 228 H---------------------------------ISQECKHLLSRIFVTNSAKRITLKEI 254
Query: 723 LNDPW 727
N PW
Sbjct: 255 KNHPW 259
>At3g50500 [T] KOG0583 Serine/threonine protein kinase
Length = 362
Score = 95.9 bits (237), Expect = 2e-19
Identities = 83/319 (26%), Positives = 144/319 (45%), Gaps = 58/319 (18%)
Query: 413 VPALPFSKRYLKTGENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITS 472
+P + S RY +++G+G G RLM ++ AVK E K D + +
Sbjct: 14 LPIMHDSDRY-DFVKDIGSGNFGVARLMTDRVTKELVAVKYI----ERGEKID--ENVQR 66
Query: 473 EYCIGTTLRHPNIISTIEIVYENNRIFQVMEYC-DYDLFA-IVMSNKMSYEEICCCFKQI 530
E +LRHPNI+ E++ + + VMEY +L+ I + + S +E F+Q+
Sbjct: 67 EIINHRSLRHPNIVRFKEVILTPSHLAIVMEYAAGGELYERICNAGRFSEDEARFFFQQL 126
Query: 531 LTGVEYLHSIGLAHRDMKLDNCVINNQGI--VKLIDFGAAEVFSYPHSKTLIESSGIVGS 588
++GV Y H++ + HRD+KL+N +++ +K+ DFG ++ S HS + VG+
Sbjct: 127 ISGVSYCHAMQICHRDLKLENTLLDGSPAPRLKICDFGYSK-SSVLHS----QPKSTVGT 181
Query: 589 DPYLAPEVCIFTKYDPRPVDIWSVAILFACMVLKKFPWKIPKLKDNSFKFFCSGRDCDSL 648
Y+APE+ + +YD + D+WS + M++ +P++ P+
Sbjct: 182 PAYIAPEILLRQEYDGKLADVWSCGVTLYVMLVGAYPFEDPQ------------------ 223
Query: 649 SALVTKTPKPPSYDNAVQSDEPAESTSKSNNPSDPNNTNIGPQRLLHSLPEETHHIIGRM 708
+P Y +Q S S P + ++ P E H+I R+
Sbjct: 224 --------EPRDYRKTIQ-------RILSVTYSIPEDLHLSP---------ECRHLISRI 259
Query: 709 VDLAPACRANIEEVLNDPW 727
PA R I E+ +D W
Sbjct: 260 FVADPATRITIPEITSDKW 278
>At2g23030 [T] KOG0583 Serine/threonine protein kinase
Length = 339
Score = 95.9 bits (237), Expect = 2e-19
Identities = 65/208 (31%), Positives = 108/208 (51%), Gaps = 15/208 (7%)
Query: 427 ENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLRHPNII 486
++LG G G RLM+ N++ AVK ++ + + + E L HPNI+
Sbjct: 8 KDLGFGNFGLARLMRNKQTNELVAVKFIDRGYKID------ENVAREIINHRALNHPNIV 61
Query: 487 STIEIVYENNRIFQVMEYC-DYDLFAIVMS-NKMSYEEICCCFKQILTGVEYLHSIGLAH 544
E+V + VMEY +LF + S + S E F+Q++ GV YLH++ + H
Sbjct: 62 RFKEVVLTPTHLGIVMEYAAGGELFERISSVGRFSEAEARYFFQQLICGVHYLHALQICH 121
Query: 545 RDMKLDNCVINNQGI--VKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFTKY 602
RD+KL+N +++ +K+ DFG ++ S HS VG+ Y+APEV ++Y
Sbjct: 122 RDLKLENTLLDGSPAPRLKICDFGYSKS-SVLHSNP----KSTVGTPAYIAPEVFCRSEY 176
Query: 603 DPRPVDIWSVAILFACMVLKKFPWKIPK 630
D + VD+WS + M++ +P++ PK
Sbjct: 177 DGKSVDVWSCGVALYVMLVGAYPFEDPK 204
>Hs9845489 [R] KOG0586 Serine/threonine protein kinase
Length = 691
Score = 95.5 bits (236), Expect = 3e-19
Identities = 65/219 (29%), Positives = 106/219 (47%), Gaps = 21/219 (9%)
Query: 421 RYLKTGENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTL 480
R LKT +G G V+L + I + AVK + S ++K+ E I L
Sbjct: 21 RLLKT---IGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSS---LQKLFREVRIMKVL 74
Query: 481 RHPNIISTIEIVYENNRIFQVMEYC------DYDLFAIVMSNKMSYEEICCCFKQILTGV 534
HPNI+ E++ ++ VMEY DY +V +M +E F+QI++ V
Sbjct: 75 NHPNIVKLFEVIETEKTLYLVMEYASGGEVFDY----LVAHGRMKEKEARAKFRQIVSAV 130
Query: 535 EYLHSIGLAHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAP 594
+Y H + HRD+K +N +++ +K+ DFG + F++ + + GS PY AP
Sbjct: 131 QYCHQKFIVHRDLKAENLLLDADMNIKIADFGFSNEFTFGN-----KLDTFCGSPPYAAP 185
Query: 595 EVCIFTKYDPRPVDIWSVAILFACMVLKKFPWKIPKLKD 633
E+ KYD VD+WS+ ++ +V P+ LK+
Sbjct: 186 ELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKE 224
>Hs9845487 [R] KOG0586 Serine/threonine protein kinase
Length = 745
Score = 95.5 bits (236), Expect = 3e-19
Identities = 65/219 (29%), Positives = 106/219 (47%), Gaps = 21/219 (9%)
Query: 421 RYLKTGENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTL 480
R LKT +G G V+L + I + AVK + S ++K+ E I L
Sbjct: 21 RLLKT---IGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSS---LQKLFREVRIMKVL 74
Query: 481 RHPNIISTIEIVYENNRIFQVMEYC------DYDLFAIVMSNKMSYEEICCCFKQILTGV 534
HPNI+ E++ ++ VMEY DY +V +M +E F+QI++ V
Sbjct: 75 NHPNIVKLFEVIETEKTLYLVMEYASGGEVFDY----LVAHGRMKEKEARAKFRQIVSAV 130
Query: 535 EYLHSIGLAHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAP 594
+Y H + HRD+K +N +++ +K+ DFG + F++ + + GS PY AP
Sbjct: 131 QYCHQKFIVHRDLKAENLLLDADMNIKIADFGFSNEFTFGN-----KLDTFCGSPPYAAP 185
Query: 595 EVCIFTKYDPRPVDIWSVAILFACMVLKKFPWKIPKLKD 633
E+ KYD VD+WS+ ++ +V P+ LK+
Sbjct: 186 ELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKE 224
>Hs22062450 [R] KOG0586 Serine/threonine protein kinase
Length = 787
Score = 95.5 bits (236), Expect = 3e-19
Identities = 65/219 (29%), Positives = 106/219 (47%), Gaps = 21/219 (9%)
Query: 421 RYLKTGENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTL 480
R LKT +G G V+L + I + AVK + S ++K+ E I L
Sbjct: 54 RLLKT---IGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSS---LQKLFREVRIMKVL 107
Query: 481 RHPNIISTIEIVYENNRIFQVMEYC------DYDLFAIVMSNKMSYEEICCCFKQILTGV 534
HPNI+ E++ ++ VMEY DY +V +M +E F+QI++ V
Sbjct: 108 NHPNIVKLFEVIETEKTLYLVMEYASGGEVFDY----LVAHGRMKEKEARAKFRQIVSAV 163
Query: 535 EYLHSIGLAHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAP 594
+Y H + HRD+K +N +++ +K+ DFG + F++ + + GS PY AP
Sbjct: 164 QYCHQKFIVHRDLKAENLLLDADMNIKIADFGFSNEFTFGN-----KLDTFCGSPPYAAP 218
Query: 595 EVCIFTKYDPRPVDIWSVAILFACMVLKKFPWKIPKLKD 633
E+ KYD VD+WS+ ++ +V P+ LK+
Sbjct: 219 ELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKE 257
>At5g63650 [T] KOG0583 Serine/threonine protein kinase
Length = 360
Score = 95.5 bits (236), Expect = 3e-19
Identities = 64/207 (30%), Positives = 108/207 (51%), Gaps = 15/207 (7%)
Query: 427 ENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLRHPNII 486
++LGAG G RL++ ++ A+K E R + + E +LRHPNII
Sbjct: 8 KDLGAGNFGVARLLRHKETKELVAMKYI------ERGRKIDENVAREIINHRSLRHPNII 61
Query: 487 STIEIVYENNRIFQVMEYCDY-DLFA-IVMSNKMSYEEICCCFKQILTGVEYLHSIGLAH 544
E++ + VMEY +LF I + + S E F+Q++ GV+Y HS+ + H
Sbjct: 62 RFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEAEARYFFQQLICGVDYCHSLQICH 121
Query: 545 RDMKLDNCVINNQ--GIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFTKY 602
RD+KL+N +++ ++K+ DFG ++ S HS+ VG+ Y+APEV +Y
Sbjct: 122 RDLKLENTLLDGSPAPLLKICDFGYSK-SSLLHSR----PKSTVGTPAYIAPEVLSRREY 176
Query: 603 DPRPVDIWSVAILFACMVLKKFPWKIP 629
D + D+WS + M++ +P++ P
Sbjct: 177 DGKHADVWSCGVTLYVMLVGGYPFEDP 203
>At5g25110 [T] KOG0583 Serine/threonine protein kinase
Length = 460
Score = 95.5 bits (236), Expect = 3e-19
Identities = 62/217 (28%), Positives = 108/217 (49%), Gaps = 5/217 (2%)
Query: 426 GENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLRHPNI 485
G LG G G V K I+ + A+K + + +++I E I +RHPNI
Sbjct: 18 GRLLGKGTFGKVYYGKEITTGESVAIKIINK--DQVKREGMMEQIKREISIMRLVRHPNI 75
Query: 486 ISTIEIVYENNRIFQVMEYCDY-DLFAIVMSNKMSYEEICCCFKQILTGVEYLHSIGLAH 544
+ E++ +IF +MEY +LF+ ++ K+ + F+Q+++ V++ HS G++H
Sbjct: 76 VELKEVMATKTKIFFIMEYVKGGELFSKIVKGKLKEDSARKYFQQLISAVDFCHSRGVSH 135
Query: 545 RDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFTKYDP 604
RD+K +N +++ G +K+ DFG + + L+ + G+ Y+APEV YD
Sbjct: 136 RDLKPENLLVDENGDLKVSDFGLSALPEQILQDGLLHTQ--CGTPAYVAPEVLRKKGYDG 193
Query: 605 RPVDIWSVAILFACMVLKKFPWKIPKLKDNSFKFFCS 641
DIWS I+ ++ P++ L K F S
Sbjct: 194 AKGDIWSCGIILYVLLAGFLPFQDENLMKMYRKIFKS 230
>At5g10270 [D] KOG0600 Cdc2-related protein kinase
Length = 505
Score = 95.5 bits (236), Expect = 3e-19
Identities = 80/251 (31%), Positives = 120/251 (46%), Gaps = 29/251 (11%)
Query: 427 ENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLRHPNII 486
E +G G G V + K I ++ A+K+ R E E + E I L H N+I
Sbjct: 30 EQIGEGTYGQVYMAKEIKTGEIVALKKIRMDNEREG---FPITAIREIKILKKLHHENVI 86
Query: 487 STIEIVY------------ENNR----IFQVMEYCDYDLFAIV--MSNKMSYEEICCCFK 528
EIV +NN+ I+ V EY D+DL + + + +I C K
Sbjct: 87 QLKEIVTSPGRDRDDQGKPDNNKYKGGIYMVFEYMDHDLTGLADRPGLRFTVPQIKCYMK 146
Query: 529 QILTGVEYLHSIGLAHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGS 588
Q+LTG+ Y H + HRD+K N +I+N+G +KL DFG A +S+ H+ L + V +
Sbjct: 147 QLLTGLHYCHVNQVLHRDIKGSNLLIDNEGNLKLADFGLARSYSHDHTGNL---TNRVIT 203
Query: 589 DPYLAPEVCI-FTKYDPRPVDIWSVAILFACMVLKK--FPWKIPKLKDNSFKFFCSGRDC 645
Y PE+ + TKY P +D+WSV +FA ++ K P K + + N C D
Sbjct: 204 LWYRPPELLLGATKYGP-AIDMWSVGCIFAELLHAKPILPGKNEQEQLNKIFELCGSPD- 261
Query: 646 DSLSALVTKTP 656
+ L V+K P
Sbjct: 262 EKLWPGVSKMP 272
>Hs16936528 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 298
Score = 95.1 bits (235), Expect = 4e-19
Identities = 79/308 (25%), Positives = 132/308 (42%), Gaps = 29/308 (9%)
Query: 427 ENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLRHPNII 486
E +G G G V + +V A+K+ R E E + E + L HPNI+
Sbjct: 8 EKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIR---EISLLKELNHPNIV 64
Query: 487 STIEIVYENNRIFQVMEYCDYDLFAIVMSNKMS---YEEICCCFKQILTGVEYLHSIGLA 543
+++++ N+++ V E+ DL + ++ ++ I Q+L G+ + HS +
Sbjct: 65 KLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVL 124
Query: 544 HRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFTKYD 603
HRD+K N +IN +G +KL DFG A F P E V + Y APE+ + KY
Sbjct: 125 HRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHE----VVTLWYRAPEILLGCKYY 180
Query: 604 PRPVDIWSVAILFACMVLKKFPWKIPKLKDNSFKFFCSGRDCDSLSALVTKTPKPPSYDN 663
VDIWS+ +FA MV ++ F + D L + P D
Sbjct: 181 STAVDIWSLGCIFAEMVTRR-------------ALFPGDSEIDQLFRIFRTLGTP---DE 224
Query: 664 AVQSDEPAESTSKSNNPSDPNNTNIGPQRLLHSLPEETHHIIGRMVDLAPACRANIEEVL 723
V P ++ PS P +++ L E+ ++ +M+ P R + + L
Sbjct: 225 VVW---PGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAAL 281
Query: 724 NDPWIQSI 731
P+ Q +
Sbjct: 282 AHPFFQDV 289
>At5g64960 [D] KOG0600 Cdc2-related protein kinase
Length = 513
Score = 95.1 bits (235), Expect = 4e-19
Identities = 83/265 (31%), Positives = 125/265 (46%), Gaps = 33/265 (12%)
Query: 427 ENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLRHPNII 486
E +G G G V + K I ++ A+K+ R E E + E I L H N+I
Sbjct: 30 EQIGEGTYGQVYMAKEIKTGEIVALKKIRMDNEREG---FPITAIREIKILKKLHHENVI 86
Query: 487 STIEIVY------------ENNR----IFQVMEYCDYDLFAIV--MSNKMSYEEICCCFK 528
EIV +NN+ I+ V EY D+DL + + + +I C K
Sbjct: 87 HLKEIVTSPGRDRDDQGKPDNNKYKGGIYMVFEYMDHDLTGLADRPGLRFTVPQIKCYMK 146
Query: 529 QILTGVEYLHSIGLAHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGS 588
Q+LTG+ Y H + HRD+K N +I+N+G +KL DFG A +S+ H+ L + V +
Sbjct: 147 QLLTGLHYCHVNQVLHRDIKGSNLLIDNEGNLKLADFGLARSYSHDHTGNL---TNRVIT 203
Query: 589 DPYLAPEVCI-FTKYDPRPVDIWSVAILFACMVLKK--FPWKIPKLKDNSFKFFCSGRDC 645
Y PE+ + TKY P +D+WSV +FA ++ K P K + N C D
Sbjct: 204 LWYRPPELLLGATKYGP-AIDMWSVGCIFAELLNGKPILPGKTENEQLNKIYELCGSPD- 261
Query: 646 DSLSALVTKTPKPPSYDNAVQSDEP 670
+S V+K P + N ++S P
Sbjct: 262 ESNWPGVSKMP----WYNQMKSSRP 282
>Hs13899225 [R] KOG0586 Serine/threonine protein kinase
Length = 688
Score = 94.7 bits (234), Expect = 5e-19
Identities = 63/215 (29%), Positives = 107/215 (49%), Gaps = 13/215 (6%)
Query: 421 RYLKTGENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTL 480
R L+T +G G V+L + I + A+K + S ++K+ E I L
Sbjct: 60 RLLRT---IGKGNSAKVKLARHILTGREVAIKIIDKTQLNPSS---LQKLFREVRIMKGL 113
Query: 481 RHPNIISTIEIVYENNRIFQVMEYCDY-DLFAIVMSN-KMSYEEICCCFKQILTGVEYLH 538
HPNI+ E++ ++ VMEY ++F ++S+ +M +E F+QI++ V Y H
Sbjct: 114 NHPNIVKLFEVIETEKTLYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAVHYCH 173
Query: 539 SIGLAHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCI 598
+ HRD+K +N +++ + +K+ DFG + F+ + GS PY APE+
Sbjct: 174 QKNIVHRDLKAENLLLDAEANIKIADFGFSNEFTLGS-----KLDTFCGSPPYAAPELFQ 228
Query: 599 FTKYDPRPVDIWSVAILFACMVLKKFPWKIPKLKD 633
KYD VDIWS+ ++ +V P+ LK+
Sbjct: 229 GKKYDGPEVDIWSLGVILYTLVSGSLPFDGHNLKE 263
>SPBC1604.14c [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 658
Score = 94.0 bits (232), Expect = 8e-19
Identities = 59/199 (29%), Positives = 107/199 (53%), Gaps = 11/199 (5%)
Query: 429 LGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLRHPNIIST 488
+G GA G V +++ N A+K+ + K+++ I +E + + H NI++
Sbjct: 392 IGQGASGDVYSARQVGTNLSVAIKKMN--INQQPKKEF---IVNEILVMKSHHHKNIVNF 446
Query: 489 IEIVYENNRIFQVMEYC-DYDLFAIVMSNKMSYEEICCCFKQILTGVEYLHSIGLAHRDM 547
I+ + + ++ VMEY L +V +N +S +I K+ L G+++LH G+ HRD+
Sbjct: 447 IDTFFYKSELWMVMEYMRGGSLTEVVTNNTLSEGQIAAICKETLEGLQHLHENGIVHRDI 506
Query: 548 KLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFTKYDPRPV 607
K DN +++ QG +KL DFG F + + + +VG+ ++APEV +Y + V
Sbjct: 507 KSDNILLSLQGDIKLTDFG----FCAQIDSNMTKRTTMVGTPYWMAPEVVTRKEYGFK-V 561
Query: 608 DIWSVAILFACMVLKKFPW 626
D+WS+ I+ MV + P+
Sbjct: 562 DVWSLGIMAIEMVEGEPPY 580
>SPAC23H4.02 [T] KOG0583 Serine/threonine protein kinase
Length = 532
Score = 94.0 bits (232), Expect = 8e-19
Identities = 64/204 (31%), Positives = 104/204 (50%), Gaps = 10/204 (4%)
Query: 426 GENLGAGAGGSVRLMKRISDNQVFAVKE-FRPKFEHESKRDYVKKITSEYCIGTTLRHPN 484
G LG G V+L K N+ A+K + + E +D K++ E I L HPN
Sbjct: 26 GRTLGQGNLAKVKLGKHFQTNEKVALKMVYNDELED---KDTWKRLQREVTILRQLHHPN 82
Query: 485 IISTIEIVYENNRIFQVMEYCDYDLFAIVMS-NKMSYEEICCCFKQILTGVEYLHSIGLA 543
II+ ++ +EY D DL ++V+ N++ F+QI+ ++Y H +A
Sbjct: 83 IITLYQVFRVPKYTVLALEYMDTDLHSMVVKHNRLDECTTRKIFRQIVHAIDYCHLHRVA 142
Query: 544 HRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFTKYD 603
HRD+KL+N ++N +VKL DFG + ++ + + +S G+ Y APEV YD
Sbjct: 143 HRDLKLENILLNKDLVVKLTDFGLS---NFMLDGSFLSTS--CGTPHYAAPEVIQGRYYD 197
Query: 604 PRPVDIWSVAILFACMVLKKFPWK 627
VD+W IL M++ +FP++
Sbjct: 198 GCDVDVWGCGILLYLMLVGEFPFE 221
>At1g67580 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 752
Score = 94.0 bits (232), Expect = 8e-19
Identities = 61/195 (31%), Positives = 102/195 (52%), Gaps = 11/195 (5%)
Query: 432 GAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLRHPNIISTIEI 491
G G V K ++ A+K+ + + E E + E I + HP+I+ E+
Sbjct: 415 GTYGVVYRAKDKKTGEIVALKKVKMEKEREG---FPLTSLREINILLSFHHPSIVDVKEV 471
Query: 492 VYENN--RIFQVMEYCDYDLFAIV--MSNKMSYEEICCCFKQILTGVEYLHSIGLAHRDM 547
V ++ IF VMEY ++DL A++ M + S E+ C Q+L GV+YLH + HRD+
Sbjct: 472 VVGSSLDSIFMVMEYMEHDLKALMETMKQRFSQSEVKCLMLQLLEGVKYLHDNWVLHRDL 531
Query: 548 KLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFTKYDPRPV 607
K N ++NN+G +K+ DFG A + P L + +V + Y APE+ + K +
Sbjct: 532 KTSNLLLNNRGELKICDFGLARQYGSP----LKPYTHLVVTLWYRAPELLLGAKQYSTAI 587
Query: 608 DIWSVAILFACMVLK 622
D+WS+ + A +++K
Sbjct: 588 DMWSLGCIMAELLMK 602
>At1g18670 [D] KOG0600 Cdc2-related protein kinase
Length = 662
Score = 94.0 bits (232), Expect = 8e-19
Identities = 68/213 (31%), Positives = 110/213 (50%), Gaps = 11/213 (5%)
Query: 416 LPFSKRYLKTGENLGAGAGGSVRLMKRISDNQVFAVKEFR-PKFEHESKRDYVKKITSEY 474
+PF + E +G G SV + ++ A+K+ R FE ES V+ + E
Sbjct: 124 VPFRSDAFEKLEKIGQGTYSSVFRARETETGRIVALKKVRFDNFEPES----VRFMAREI 179
Query: 475 CIGTTLRHPNIISTIEIVYE--NNRIFQVMEYCDYDLFAIVMSNKMSYE--EICCCFKQI 530
I L HPNII IV + I V EY ++DL ++ S + + +I C KQ+
Sbjct: 180 LILRKLNHPNIIKLEGIVTSKLSCSIHLVFEYMEHDLTGLLSSPDIDFTTPQIKCYMKQL 239
Query: 531 LTGVEYLHSIGLAHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDP 590
L+G+++ H+ G+ HRD+K N ++NN+GI+K+ DFG A + +K + S V +
Sbjct: 240 LSGLDHCHARGVMHRDIKGSNLLVNNEGILKVADFGLANFCNASGNKQPLTSR--VVTLW 297
Query: 591 YLAPEVCIFTKYDPRPVDIWSVAILFACMVLKK 623
Y PE+ + VD+WSV +FA +++ K
Sbjct: 298 YRPPELLLGATEYGASVDLWSVGCVFAELLIGK 330
>At1g10940 [T] KOG0583 Serine/threonine protein kinase
Length = 363
Score = 94.0 bits (232), Expect = 8e-19
Identities = 64/207 (30%), Positives = 109/207 (51%), Gaps = 19/207 (9%)
Query: 427 ENLGAGAGGSVRLMKRISDNQVFAVK--EFRPKFEHESKRDYVKKITSEYCIGTTLRHPN 484
+++GAG G RLMK + ++ A+K E PK + R+ + +LRHPN
Sbjct: 8 KDIGAGNFGVARLMKVKNSKELVAMKYIERGPKIDENVAREIINH--------RSLRHPN 59
Query: 485 IISTIEIVYENNRIFQVMEYC-DYDLFAIVMS-NKMSYEEICCCFKQILTGVEYLHSIGL 542
II E+V + MEY +LF + S + S +E F+Q+++GV Y H++ +
Sbjct: 60 IIRFKEVVLTPTHLAIAMEYAAGGELFERICSAGRFSEDEARYFFQQLISGVSYCHAMQI 119
Query: 543 AHRDMKLDNCVINNQGI--VKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFT 600
HRD+KL+N +++ +K+ DFG ++ S HS+ VG+ Y+APEV
Sbjct: 120 CHRDLKLENTLLDGSPAPRLKICDFGYSK-SSLLHSR----PKSTVGTPAYIAPEVLSRR 174
Query: 601 KYDPRPVDIWSVAILFACMVLKKFPWK 627
+YD + D+WS + M++ +P++
Sbjct: 175 EYDGKMADVWSCGVTLYVMLVGAYPFE 201
>At5g60550 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kinase beta
and related serine/threonine protein kinases
Length = 407
Score = 93.6 bits (231), Expect = 1e-18
Identities = 61/217 (28%), Positives = 104/217 (47%), Gaps = 20/217 (9%)
Query: 429 LGAGAGGSVRLMKRISDNQVFAVKEFRP----KFEHESKRDYVKKITSEYCIGTTLRHPN 484
+G+G+ G V L + D Q +A+K F + + + E I L HPN
Sbjct: 115 IGSGSYGKVVLYRSTLDGQYYAIKAFHKSHLLRLRVAPSETAMSDVLREVMIMKILEHPN 174
Query: 485 IISTIEIVY--ENNRIFQVMEYCD----YDLFAI--VMSNKMSYEEICCCFKQILTGVEY 536
I++ IE++ E + + V+EY D YD + K + + + + I+TG+ Y
Sbjct: 175 IVNLIEVIDDPETDHFYMVLEYVDGKWVYDGSGPPGALGEKTARKYL----RDIVTGLMY 230
Query: 537 LHSIGLAHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEV 596
LH+ + H D+K DN ++ + G VK+ DF ++VF + G+ + APE
Sbjct: 231 LHAHDVIHGDIKPDNLLVTSSGTVKIGDFSVSQVFKDDDDQLRRSP----GTPVFTAPEC 286
Query: 597 CIFTKYDPRPVDIWSVAILFACMVLKKFPWKIPKLKD 633
C+ Y R D W+V + CM+L ++P+ L+D
Sbjct: 287 CLGITYSGRAADTWAVGVTLYCMILGQYPFLADTLQD 323
>7296346 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 952
Score = 93.6 bits (231), Expect = 1e-18
Identities = 68/207 (32%), Positives = 110/207 (52%), Gaps = 20/207 (9%)
Query: 432 GAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLR--HPNIISTI 489
G G V K N++ A+K + + E E ITS I T L+ HPNI++
Sbjct: 567 GTYGVVYRAKDKRTNEIVALKRLKMEKEKEGF-----PITSLREINTLLKGQHPNIVTVR 621
Query: 490 EIVYENN--RIFQVMEYCDYDLFAIVMSNKMSYE-----EICCCFKQILTGVEYLHSIGL 542
EIV +N +IF VM+Y ++DL +++ + K + E+ C +Q+L V +LH +
Sbjct: 622 EIVVGSNMDKIFIVMDYVEHDLKSLMETMKNRKQSFFPGEVKCLTQQLLRAVAHLHDNWI 681
Query: 543 AHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFTKY 602
HRD+K N +++++GI+K+ DFG A + P K + +V + Y APE+ + +
Sbjct: 682 LHRDLKTSNLLLSHKGILKVGDFGLAREYGSPIKK----YTSLVVTLWYRAPELLLCSPV 737
Query: 603 DPRPVDIWSVAILFA--CMVLKKFPWK 627
P+D+WSV +FA +L FP K
Sbjct: 738 YSTPIDVWSVGCIFAEFLQMLPLFPGK 764
>YOR233w [T] KOG0583 Serine/threonine protein kinase
Length = 800
Score = 93.2 bits (230), Expect = 1e-18
Identities = 81/254 (31%), Positives = 119/254 (45%), Gaps = 25/254 (9%)
Query: 426 GENLGAGAGGSVRL--MKRISDNQV---FAVKEFRPKFEHESKRDYVK--KITSEYCIGT 478
G LG G G V+L K S N+V A+K R K+D K KI E
Sbjct: 49 GSTLGEGEFGKVKLGWTKASSSNEVPKQVAIKLIR---RDTIKKDADKEIKIYREINALK 105
Query: 479 TLRHPNIISTIEIVYENNRIFQVMEYCDYDLFAIVMSNKMSYEEICCC--FKQILTGVEY 536
L HPNII E++ + I V+E+ F + K +E C F Q+++GV Y
Sbjct: 106 HLTHPNIIYLEEVLQNSKYIGIVLEFVSGGEFYKYIQRKRRLKESSACRLFAQLISGVNY 165
Query: 537 LHSIGLAHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEV 596
+H GL HRD+KL+N +++ + + DFG F L+++S GS Y APE+
Sbjct: 166 MHYKGLVHRDLKLENLLLDKHENLVITDFGFVNEFF--EDNELMKTS--CGSPCYAAPEL 221
Query: 597 CIFTK-YDPRPVDIWSVAILFACMVLKKFPWKIPKLKDNSFKFFCSGRDCDSLSALVTKT 655
+ TK Y+ R D+WS ++ M+ PW D+ + +G D L +T+T
Sbjct: 222 VVSTKAYEARKADVWSCGVILYAMLAGYLPW------DDDHE-NPTGDDIARLYKYITQT 274
Query: 656 P-KPPSYDNAVQSD 668
P K P Y + D
Sbjct: 275 PLKFPEYITPIPRD 288
>CE26076 [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 503
Score = 93.2 bits (230), Expect = 1e-18
Identities = 69/243 (28%), Positives = 119/243 (48%), Gaps = 11/243 (4%)
Query: 409 AASHVPALPFSKRYLKTGENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVK 468
AA+ P P S + + LG GA G V L+ + +V A + + ++SK D++
Sbjct: 12 AAAVAPQQPES--LYRVVQTLGEGAFGEVLLIVNTKNPEVAAAMK-KINIANKSK-DFID 67
Query: 469 KITSEYCIG---TTLRHPNIISTIEIVYENNRIFQVMEYCDY-DLFAIVMSN-KMSYEEI 523
I EY + + + H N+I I + + + +EY D +LF + + MS
Sbjct: 68 NIRKEYLLQKRVSAVGHDNVIRMIGMRNDPQFYYLFLEYADGGELFDKIEPDCGMSPVFA 127
Query: 524 CCCFKQILTGVEYLHSIGLAHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESS 583
FKQ++ G++++H + HRD+K +N ++ ++K+ DFG A ++ + L++ S
Sbjct: 128 QFYFKQLICGLKFIHDNDVVHRDIKPENLLLTGTHVLKISDFGMATLYRNKGEERLLDLS 187
Query: 584 GIVGSDPYLAPEVCIFTKYDPRPVDIWSVAILFACMVLKKFPWKIPKLKDNSFKFFCSGR 643
G+ PY APE+C KY PVD+WS I+ M+ + PW S+ + S
Sbjct: 188 --CGTIPYAAPELCAGKKYRGPPVDVWSSGIVLIAMLTGELPWDRASDASQSYMGWISNT 245
Query: 644 DCD 646
D
Sbjct: 246 SLD 248
>At4g18700 [T] KOG0583 Serine/threonine protein kinase
Length = 489
Score = 93.2 bits (230), Expect = 1e-18
Identities = 60/202 (29%), Positives = 98/202 (47%), Gaps = 5/202 (2%)
Query: 426 GENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLRHPNI 485
G+ LG G V L + + N+ A+K E K + I E I +RHPNI
Sbjct: 29 GKLLGHGTFAKVYLARNVKTNESVAIKVIDK--EKVLKGGLIAHIKREISILRRVRHPNI 86
Query: 486 ISTIEIVYENNRIFQVMEYC-DYDLFAIVMSNKMSYEEICCCFKQILTGVEYLHSIGLAH 544
+ E++ +I+ VMEY +LF V ++ E F+Q+++ V + H+ G+ H
Sbjct: 87 VQLFEVMATKAKIYFVMEYVRGGELFNKVAKGRLKEEVARKYFQQLISAVTFCHARGVYH 146
Query: 545 RDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFTKYDP 604
RD+K +N +++ G +K+ DFG + V L + G+ Y+APEV YD
Sbjct: 147 RDLKPENLLLDENGNLKVSDFGLSAVSDQIRQDGLFHT--FCGTPAYVAPEVLARKGYDA 204
Query: 605 RPVDIWSVAILFACMVLKKFPW 626
VDIWS ++ ++ P+
Sbjct: 205 AKVDIWSCGVILFVLMAGYLPF 226
>7301213 [R] KOG0589 Serine/threonine protein kinase
Length = 841
Score = 93.2 bits (230), Expect = 1e-18
Identities = 71/252 (28%), Positives = 117/252 (46%), Gaps = 41/252 (16%)
Query: 429 LGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLRHPNIIST 488
+G G+ G L +R SD K+ RD +E + + L HPNI+S
Sbjct: 111 VGQGSFGIAILYRRKSDGHQIVFKQINLSELSPPGRDLAM---NEVDVFSKLHHPNIVSY 167
Query: 489 IEIVYENNRIFQVMEYCDYDLFAIVMSN---KMSYEE--ICCCFKQILTGVEYLHSIGLA 543
+ ++N + MEY D A +++ K+ + E I F+QI + + Y+HS +
Sbjct: 168 LGSFIKDNTLLIEMEYADGGTLAQIIAERQGKLHFPERYIIAVFEQISSAINYMHSENIL 227
Query: 544 HRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFTKYD 603
HRD+K N +N +GIVK+ DFG +++ + T I + ++G+ Y +PE+C +YD
Sbjct: 228 HRDLKTANVFLNRRGIVKIGDFGISKIMN-----TKIHAQTVLGTPYYFSPEMCEGKEYD 282
Query: 604 PRPVDIWSVAILFA--CMVLKKFPWKIPKLKDNSFKFFCSGRDCDSLSALVTK------T 655
+ DIW++ + C + K F +LS LVTK T
Sbjct: 283 NKS-DIWALGCILGEMCCLKKTFA-------------------ASNLSELVTKIMAGNYT 322
Query: 656 PKPPSYDNAVQS 667
P P Y + ++S
Sbjct: 323 PVPSGYTSGLRS 334
>SPCC1259.13 [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 496
Score = 92.8 bits (229), Expect = 2e-18
Identities = 68/207 (32%), Positives = 104/207 (49%), Gaps = 12/207 (5%)
Query: 426 GENLGAGAGGSVRLMKRISDN-QVFAVKEFRPKFEHESKRD--YVKKITSEYCIGTTLR- 481
G +G GA SVRL DN +++AVK K + +++ SE +
Sbjct: 13 GREIGTGAFASVRLC--YDDNAKIYAVKFVNKKHATSCMNAGVWARRMASEIQLHKLCNG 70
Query: 482 HPNIISTIEIVYENNRIFQVMEYCDY-DLFAIVMSNKMSYEEIC-CCFKQILTGVEYLHS 539
H NII + V+E+ DLF + + E++ F Q++ G+ ++HS
Sbjct: 71 HKNIIHFYNTAENPQWRWVVLEFAQGGDLFDKIEPDVGIDEDVAQFYFAQLMEGISFMHS 130
Query: 540 IGLAHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIF 599
G+AHRD+K +N +++ G +K+ DFG A +FSY L+ S VGS PY APE I
Sbjct: 131 KGVAHRDLKPENILLDYNGNLKISDFGFASLFSYKGKSRLLNSP--VGSPPYAAPE--IT 186
Query: 600 TKYDPRPVDIWSVAILFACMVLKKFPW 626
+YD VD+WS I+ ++L PW
Sbjct: 187 QQYDGSKVDVWSCGIILFALLLGNTPW 213
>Hs4502709 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 297
Score = 92.8 bits (229), Expect = 2e-18
Identities = 81/310 (26%), Positives = 134/310 (43%), Gaps = 30/310 (9%)
Query: 427 ENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLRHPNII 486
E +G G G V + + QV A+K+ R + E E + E + LRHPNI+
Sbjct: 8 EKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIR---EISLLKELRHPNIV 64
Query: 487 STIEIVYENNRIFQVMEYCDYDLF----AIVMSNKMSYEEICCCFKQILTGVEYLHSIGL 542
S +++ +++R++ + E+ DL +I M + QIL G+ + HS +
Sbjct: 65 SLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCHSRRV 124
Query: 543 AHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFTKY 602
HRD+K N +I+++G +KL DFG A F P E V + Y +PEV + +
Sbjct: 125 LHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHE----VVTLWYRSPEVLLGSAR 180
Query: 603 DPRPVDIWSVAILFACMVLKKFPWKIPKLKDNSFKFFCSGRDCDSLSALVTKTPKPPSYD 662
PVDIWS+ +FA + KK + D F+ F + + + + + Y
Sbjct: 181 YSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPN--NEVWPEVESLQDYK 238
Query: 663 NAVQSDEPAESTSKSNNPSDPNNTNIGPQRLLHSLPEETHHIIGRMVDLAPACRANIEEV 722
N +P S N L E ++ +M+ PA R + +
Sbjct: 239 NTFPKWKPGSLASHVKN-----------------LDENGLDLLSKMLIYDPAKRISGKMA 281
Query: 723 LNDPWIQSID 732
LN P+ +D
Sbjct: 282 LNHPYFNDLD 291
>At5g39420 [D] KOG0600 Cdc2-related protein kinase
Length = 576
Score = 92.8 bits (229), Expect = 2e-18
Identities = 66/212 (31%), Positives = 114/212 (53%), Gaps = 10/212 (4%)
Query: 416 LPFSKRYLKTGENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYC 475
+P + E +G G SV + + ++ A+K+ KF++ + + ++ + E
Sbjct: 98 VPLKAEAFQKLEKIGQGTYSSVFRAREVETGKMVALKKV--KFDN-LQPESIRFMAREIL 154
Query: 476 IGTTLRHPNIISTIEIVYE--NNRIFQVMEYCDYDLFAIVMSNKMSYEE--ICCCFKQIL 531
I L HPNI+ IV ++ I+ V EY ++DL + + + + E I C KQ+L
Sbjct: 155 ILRKLNHPNIMKLEGIVTSRASSSIYLVFEYMEHDLAGLSSNPDIRFTEPQIKCYMKQLL 214
Query: 532 TGVEYLHSIGLAHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPY 591
G+E+ H G+ HRD+K N ++NN+G++KL DFG A V + P +K + S V + Y
Sbjct: 215 WGLEHCHMRGVIHRDIKASNILVNNKGVLKLGDFGLANVVT-PSNKNQLTSR--VVTLWY 271
Query: 592 LAPEVCIFTKYDPRPVDIWSVAILFACMVLKK 623
APE+ + + VD+WSV +FA +++ K
Sbjct: 272 RAPELLMGSTSYGVSVDLWSVGCVFAEILMGK 303
>At3g06030 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 651
Score = 92.8 bits (229), Expect = 2e-18
Identities = 60/208 (28%), Positives = 107/208 (50%), Gaps = 8/208 (3%)
Query: 424 KTGENLGAGAGGSVRLMKRISDNQVFAVKEFR---PKFEHESKRDYVKKITSEYCIGTTL 480
+ GE +G GA G V + + ++ A+K+ E + +++++ E + L
Sbjct: 69 RKGELIGCGAFGRVYMGMNLDSGELLAIKQVLIAPSSASKEKTQGHIRELEEEVQLLKNL 128
Query: 481 RHPNIISTIEIVYENNRIFQVMEYCDYDLFAIVMSNKMSYEE--ICCCFKQILTGVEYLH 538
HPNI+ + V E++ + +ME+ + ++ S+ E I KQ+L G+EYLH
Sbjct: 129 SHPNIVRYLGTVRESDSLNILMEFVPGGSISSLLEKFGSFPEPVIIMYTKQLLLGLEYLH 188
Query: 539 SIGLAHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCI 598
+ G+ HRD+K N +++N+G ++L DFGA++ T+ + + G+ ++APEV +
Sbjct: 189 NNGIMHRDIKGANILVDNKGCIRLADFGASK--KVVELATVNGAKSMKGTPYWMAPEVIL 246
Query: 599 FTKYDPRPVDIWSVAILFACMVLKKFPW 626
T + DIWSV M K PW
Sbjct: 247 QTGHS-FSADIWSVGCTVIEMATGKPPW 273
>SPAC57A10.02 [D] KOG0588 Serine/threonine protein kinase
Length = 775
Score = 92.4 bits (228), Expect = 2e-18
Identities = 79/305 (25%), Positives = 132/305 (42%), Gaps = 57/305 (18%)
Query: 426 GENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLRHPNI 485
G +LG+G S RL K Q+ VK E S + +I E + + HPN+
Sbjct: 13 GLSLGSGGPNSSRLAKHRETGQLAVVKPIVGWSELTSSQQ--ARIEGELVLLRLIEHPNV 70
Query: 486 ISTIEIVYENNRIFQVMEYCDYDLFAIVMSNKMSYEE--ICCCFKQILTGVEYLHSIGLA 543
+ I+++ ++F V+EY M K S+ E QIL G+EY H + +
Sbjct: 71 LQLIDVISAQEQLFVVVEYMPGGELFDCMLRKGSFTEQDTAKFLWQILCGLEYCHKLHIC 130
Query: 544 HRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFTKYD 603
HRD+K +N ++ G +K+ +FG A S L+++S GS Y +PE+ + YD
Sbjct: 131 HRDLKPENLYLDAHGSIKIGEFGMA---SIQQPGKLLQTS--CGSPHYASPEIIMGRSYD 185
Query: 604 PRPVDIWSVAILFACMVLKKFPWKIPKLKDNSFKFFCSGRDCDSLSALVTKTPKPPSYDN 663
DIWS I+F ++ K P+ D D++ +L+ K +
Sbjct: 186 GCASDIWSCGIIFFALLTGKLPF-----------------DDDNIRSLLLKVCQG----- 223
Query: 664 AVQSDEPAESTSKSNNPSDPNNTNIGPQRLLHSLPEETHHIIGRMVDLAPACRANIEEVL 723
Q + P +NI PQ H++ RM+D+ + R +E++
Sbjct: 224 --QFEMP---------------SNISPQ---------AQHLLYRMLDVDSSTRITMEQIR 257
Query: 724 NDPWI 728
P++
Sbjct: 258 EHPFL 262
>CE18454 [T] KOG4717 Serine/threonine protein kinase
Length = 1016
Score = 92.4 bits (228), Expect = 2e-18
Identities = 89/320 (27%), Positives = 148/320 (45%), Gaps = 32/320 (10%)
Query: 427 ENLGAGAGGSVRLMKRISDNQVFAVKEF-RPKFEHESKRDYVKKITSEYCIGTTLRHPNI 485
+ +G G V+L K + ++ AVK + K + S +K++ C+ ++H NI
Sbjct: 31 KTIGQGHFAVVKLAKHVFTGEMVAVKIIDKTKMDEASTSQIMKEVR---CM-KLVQHANI 86
Query: 486 ISTIEIVYENNRIFQVMEYCDYDLFAIVMSNKMSYEEICC--CFKQILTGVEYLHSIGLA 543
+ E++ +IF ++E DYDL ++ ++ E F QI+T ++Y H + +
Sbjct: 87 VRLYEVLDTQTKIFLILELGDYDLHDFIIKHEKGVCESLAQQYFCQIMTAIDYCHQLHVV 146
Query: 544 HRDMKLDNCVINNQ-GIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFTKY 602
HRD+K +N V + G+VKL DFG + SY + L S G + Y APE+ + Y
Sbjct: 147 HRDLKPENVVFFEKLGMVKLTDFGFSN--SYEPGEQLNTSCGSLA---YSAPEILLGDSY 201
Query: 603 DPRPVDIWSVAILFACMVLKKFPWK-------IPKLKDNSFKF-FCSGRDCDSL--SALV 652
D VD+WS+ ++ +V + P++ + K+ D + +C +L S LV
Sbjct: 202 DAPAVDVWSLGVILYMLVCGRLPFQEANDSETLTKILDCKYSIPDVLSDECRNLIQSMLV 261
Query: 653 TKTPKPPSYDNAVQSDEPAESTSKSNNPSDPNNTNIGPQRLLHSLPEETH-HIIGRMVDL 711
+ K S + V STS +T I P + H LP H II +MV
Sbjct: 262 REPQKRASLEKIV-------STSWVQAGDRGLSTAI-PLIVRHHLPTSAHATIIEQMVAG 313
Query: 712 APACRANIEEVLNDPWIQSI 731
A A +I L + S+
Sbjct: 314 AIASEEDILRFLENDEYNSV 333
>At5g39440 [T] KOG0583 Serine/threonine protein kinase
Length = 494
Score = 92.4 bits (228), Expect = 2e-18
Identities = 67/206 (32%), Positives = 106/206 (50%), Gaps = 12/206 (5%)
Query: 424 KTGENLGAGAGGSVRLMKRISDNQVFAVKEF-RPKFEHESKRDYVKKITSEYCIGTTLRH 482
+ G+ LG G+ V+L ++ A+K R K ++ K+ E I L H
Sbjct: 20 RIGKTLGHGSFAKVKLALHVATGHKVAIKILNRSKIKNMGIEI---KVQREIKILRFLMH 76
Query: 483 PNIISTIEIVYENNRIFQVMEYCDY-DLFA-IVMSNKMSYEEICCCFKQILTGVEYLHSI 540
P+II E++ N I+ VMEY +LF IV K+ +E F+QI++GVEY H
Sbjct: 77 PHIIRQYEVIETPNDIYVVMEYVKSGELFDYIVEKGKLQEDEARHLFQQIISGVEYCHRN 136
Query: 541 GLAHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFT 600
+ HRD+K +N ++++Q +K++DFG + V H +++S GS Y APEV
Sbjct: 137 MIVHRDLKPENVLLDSQCNIKIVDFGLSNVM---HDGHFLKTS--CGSPNYAAPEVISGK 191
Query: 601 KYDPRPVDIWSVAILFACMVLKKFPW 626
Y P VDIWS ++ ++ P+
Sbjct: 192 PYGP-DVDIWSCGVILYALLCGTLPF 216
>At1g18150 [T] KOG0660 Mitogen-activated protein kinase
Length = 589
Score = 92.4 bits (228), Expect = 2e-18
Identities = 86/315 (27%), Positives = 145/315 (45%), Gaps = 34/315 (10%)
Query: 427 ENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLRHPNII 486
E +G G+ G V + A+K+ FEH S +I E + LRHP+++
Sbjct: 108 EVVGKGSYGVVASAVDSHTGERVAIKKINDVFEHVSD---ATRILREIKLLRLLRHPDVV 164
Query: 487 STIEIVYENNR-----IFQVMEYCDYDLFAIVMSNK-MSYEEICCCFKQILTGVEYLHSI 540
I+ +R I+ V E + DL ++ +N ++ E Q+L G++Y+H+
Sbjct: 165 EIKHIMLPPSRREFRDIYVVFELMESDLHQVIKANDDLTPEHYQFFLYQLLRGLKYVHAA 224
Query: 541 GLAHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVC--I 598
+ HRD+K N + N +K+ DFG A V S+ + T I + V + Y APE+C
Sbjct: 225 NVFHRDLKPKNILANADCKLKICDFGLARV-SFNDAPTAIFWTDYVATRWYRAPELCGSF 283
Query: 599 FTKYDPRPVDIWSVAILFACMVLKK--FPWKIPKLKDNSFKFFCSGRDCDSLSALVTKTP 656
F+KY P +DIWSV +FA M+L K FP K + + F +S+S + +
Sbjct: 284 FSKYTP-AIDIWSVGCIFAEMLLGKPLFPGKNVVHQLDLMTDFLGTPPPESISRI--RNE 340
Query: 657 KPPSYDNAVQSDEPAESTSKSNNPSDPNNTNIGPQRLLHSLPEETHHIIGRMVDLAPACR 716
K Y ++++ +P + K +DP ++ R++ P R
Sbjct: 341 KARRYLSSMRKKQPVPFSHKFPK-ADP----------------LALRLLERLLAFDPKDR 383
Query: 717 ANIEEVLNDPWIQSI 731
A+ E+ L DP+ +
Sbjct: 384 ASAEDALADPYFSGL 398
>CE29466 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 390
Score = 92.0 bits (227), Expect = 3e-18
Identities = 78/309 (25%), Positives = 144/309 (46%), Gaps = 21/309 (6%)
Query: 429 LGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLRHPNIIST 488
L AGA G+V + + Q A+K+ + F K+ E+ + TT++HPNII
Sbjct: 44 LNAGAQGTVVMADDLVTTQRVAIKKMQQPFVMTMS---AKRAYREFILLTTIKHPNIIRL 100
Query: 489 IEIVYENN------RIFQVMEYCDYDLFAIVMSNKMSYEEICCCFKQILTGVEYLHSIGL 542
+ + ++ VME ++L ++ ++ ++ + Q L +++LH+ G+
Sbjct: 101 LNAFTPDTSLSTFREVYLVMELMTHNLHEVIHRLRLDHKTLSFFVYQSLCAIKHLHNSGV 160
Query: 543 AHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFTKY 602
HRD+K N V+N++ ++K++DFG A + T + S V + Y APEV + Y
Sbjct: 161 IHRDLKPSNIVVNDRCVLKVLDFGLAR---KKNVDTSMRMSDYVVTRYYRAPEVILGLPY 217
Query: 603 DPRPVDIWSVAILFACMV--LKKFPWKIPKLKDNSFKFFCSGRDCDSLSALVTKTPKPPS 660
+ VDIWSV +FA M+ FP K ++ + + G D + + + S
Sbjct: 218 SEK-VDIWSVGCIFAEMINHTVLFPGK-DRIDQWTKIYSVLGTPDDHFISQLGQ-----S 270
Query: 661 YDNAVQSDEPAESTSKSNNPSDPNNTNIGPQRLLHSLPEETHHIIGRMVDLAPACRANIE 720
V+S ++ + S D N +H P ++ M+ + P R ++E
Sbjct: 271 AAMYVRSLPRHQARAFSEIVPDTNFLPETENPRVHLTPHVARDLLFNMLKINPEERYSVE 330
Query: 721 EVLNDPWIQ 729
+ LN P+++
Sbjct: 331 DALNHPYVK 339
>At5g63370 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 612
Score = 92.0 bits (227), Expect = 3e-18
Identities = 81/323 (25%), Positives = 144/323 (44%), Gaps = 45/323 (13%)
Query: 429 LGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITS--EYCIGTTLRHPNII 486
+ G G V + ++ A+K+ + K E + +Y +TS E I + HP I+
Sbjct: 303 INEGTYGIVYKARDEKTKEIVALKKIKMK-EDRFEEEYGFPLTSLREINILLSCNHPAIV 361
Query: 487 STIEIVY---ENNRIFQVMEYCDYDLFAIVMSNK--MSYEEICCCFKQILTGVEYLHSIG 541
+ E+V +N ++ VME+ ++DL ++ K S E+ C Q+L G++YLH+
Sbjct: 362 NVKEVVVGGKNDNDVYMVMEHLEHDLRGVMDRRKEPFSTSEVKCLMMQLLDGLKYLHTNW 421
Query: 542 LAHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFTK 601
+ HRD+K N ++NN G +K+ DFG A + P + + +V + Y PE+ + K
Sbjct: 422 IIHRDLKPSNLLMNNCGELKICDFGMARQYGSP----IKPYTQMVITQWYRPPELLLGAK 477
Query: 602 YDPRPVDIWSVAILFACMVLKK--FPWKIPKLKDNSFKFFCSGRDCDSLSALVTKTPKPP 659
VD+WSV + A ++ +K FP K + D L + P
Sbjct: 478 EYSTAVDMWSVGCIMAELLSQKPLFPGK---------------SELDQLQKIFAVLGTP- 521
Query: 660 SYDNAVQSDEPAESTSKSNNPSDPNN---------TNIGPQRLLHSLPEETHHIIGRMVD 710
+ A+ + +K+ P+ P N + +G Q L E ++ ++
Sbjct: 522 --NEAIWPGFSSFPNAKAKFPTQPYNMLRKKFPAISFVGGQ----ILSERGFDLLNSLLT 575
Query: 711 LAPACRANIEEVLNDPWIQSIDM 733
L P R +E+ LN W + +
Sbjct: 576 LDPEKRLTVEDALNHGWFHEVPL 598
>At1g60940 [T] KOG0583 Serine/threonine protein kinase
Length = 361
Score = 92.0 bits (227), Expect = 3e-18
Identities = 64/207 (30%), Positives = 108/207 (51%), Gaps = 19/207 (9%)
Query: 427 ENLGAGAGGSVRLMKRISDNQVFAVK--EFRPKFEHESKRDYVKKITSEYCIGTTLRHPN 484
+++GAG G RLM+ + ++ A+K E PK + R+ + +LRHPN
Sbjct: 8 KDIGAGNFGVARLMRVKNSKELVAMKYIERGPKIDENVAREIINH--------RSLRHPN 59
Query: 485 IISTIEIVYENNRIFQVMEYC-DYDLFAIVMS-NKMSYEEICCCFKQILTGVEYLHSIGL 542
II E+V I MEY +LF + S + S +E F+Q+++GV Y H++ +
Sbjct: 60 IIRFKEVVLTPTHIAIAMEYAAGGELFERICSAGRFSEDEARYFFQQLISGVSYCHAMQI 119
Query: 543 AHRDMKLDNCVINNQGI--VKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFT 600
HRD+KL+N +++ +K+ DFG ++ S HS VG+ Y+APEV
Sbjct: 120 CHRDLKLENTLLDGSPAPRLKICDFGYSK-SSLLHSM----PKSTVGTPAYIAPEVLSRG 174
Query: 601 KYDPRPVDIWSVAILFACMVLKKFPWK 627
+YD + D+WS + M++ +P++
Sbjct: 175 EYDGKMADVWSCGVTLYVMLVGAYPFE 201
>7302464 [R] KOG0586 Serine/threonine protein kinase
Length = 739
Score = 92.0 bits (227), Expect = 3e-18
Identities = 59/213 (27%), Positives = 106/213 (49%), Gaps = 18/213 (8%)
Query: 427 ENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLRHPNII 486
+ +G G V+L K + + A+K + + ++K+ E I L HPNI+
Sbjct: 155 KTIGKGNFAKVKLAKHLPTGKEVAIKIID---KTQLNPGSLQKLFREVRIMKMLDHPNIV 211
Query: 487 STIEIVYENNRIFQVMEYC------DYDLFAIVMSNKMSYEEICCCFKQILTGVEYLHSI 540
+++ ++ +MEY DY +V+ +M +E F+QI++ V+Y H
Sbjct: 212 KLFQVIETEKTLYLIMEYASGGEVFDY----LVLHGRMKEKEARVKFRQIVSAVQYCHQK 267
Query: 541 GLAHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFT 600
+ HRD+K +N +++++ +K+ DFG + F+ P SK GS PY APE+
Sbjct: 268 RIIHRDLKAENLLLDSELNIKIADFGFSNEFT-PGSKL----DTFCGSPPYAAPELFQGK 322
Query: 601 KYDPRPVDIWSVAILFACMVLKKFPWKIPKLKD 633
KYD VD+WS+ ++ +V P+ L++
Sbjct: 323 KYDGPEVDVWSLGVILYTLVSGSLPFDGSTLRE 355
>Hs8923922 [R] KOG0586 Serine/threonine protein kinase
Length = 795
Score = 91.7 bits (226), Expect = 4e-18
Identities = 59/213 (27%), Positives = 102/213 (47%), Gaps = 18/213 (8%)
Query: 427 ENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLRHPNII 486
+ +G G V+L + + + AVK + + ++K+ E I L HPNI+
Sbjct: 64 KTIGKGNFAKVKLARHVLTGREVAVKIID---KTQLNPTSLQKLFREVRIMKILNHPNIV 120
Query: 487 STIEIVYENNRIFQVMEYC------DYDLFAIVMSNKMSYEEICCCFKQILTGVEYLHSI 540
E++ ++ VMEY DY +V +M +E F+QI++ V+Y H
Sbjct: 121 KLFEVIETEKTLYLVMEYASGGEVFDY----LVAHGRMKEKEARAKFRQIVSAVQYCHQK 176
Query: 541 GLAHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFT 600
+ HRD+K +N +++ +K+ DFG + F+ + + GS PY APE+
Sbjct: 177 YIVHRDLKAENLLLDGDMNIKIADFGFSNEFTVGN-----KLDTFCGSPPYAAPELFQGK 231
Query: 601 KYDPRPVDIWSVAILFACMVLKKFPWKIPKLKD 633
KYD VD+WS+ ++ +V P+ LK+
Sbjct: 232 KYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKE 264
>CE12478 [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 484
Score = 91.7 bits (226), Expect = 4e-18
Identities = 55/188 (29%), Positives = 96/188 (50%), Gaps = 10/188 (5%)
Query: 464 RDYVKKITSEYCIGTTLR-HPNIISTIEIVYENNRIFQVMEYCDY-DLFAIVMSN-KMSY 520
R+Y+ I E I +L H N+I + + + +EY D DL+ + S S
Sbjct: 64 REYIDAIRKEITIQESLTGHENVIQVLGKESDAQFCYMFLEYADGGDLYEKITSGCSFSL 123
Query: 521 EEICCCFKQILTGVEYLHSIGLAHRDMKLDNCVINNQGI-----VKLIDFGAAEVFSYPH 575
EE FKQ++ G+++LH +AHRD+K +N ++ + G +K+ DFG A + Y
Sbjct: 124 EEAHSYFKQLVNGLKFLHCRDVAHRDIKPENLMLTHSGKSEMRHLKIADFGLATWYRYKG 183
Query: 576 SKTLIESSGIVGSDPYLAPEVCIFTKYDPRPVDIWSVAILFACMVLKKFPWKIPKLKDNS 635
++ + E GS Y+APE+ +Y +DIWS ++ M+ ++ PW+ P + +
Sbjct: 184 AELIFEQR--CGSVEYVAPEIYTGAQYRGPQIDIWSAGVVLLAMLTRQLPWEFPCMTNKR 241
Query: 636 FKFFCSGR 643
+ F+ R
Sbjct: 242 YFFWMKNR 249
>At5g10930 [T] KOG0583 Serine/threonine protein kinase
Length = 445
Score = 91.7 bits (226), Expect = 4e-18
Identities = 61/215 (28%), Positives = 105/215 (48%), Gaps = 4/215 (1%)
Query: 426 GENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLRHPNI 485
G LG G V K I + A+K K + + +++I E I +RHPNI
Sbjct: 15 GRLLGKGTFAKVYYGKEIIGGECVAIKVIN-KDQVMKRPGMMEQIKREISIMKLVRHPNI 73
Query: 486 ISTIEIVYENNRIFQVMEYCDY-DLFAIVMSNKMSYEEICCCFKQILTGVEYLHSIGLAH 544
+ E++ +IF VME+ +LF + K+ + F+Q+++ V+Y HS G++H
Sbjct: 74 VELKEVMATKTKIFFVMEFVKGGELFCKISKGKLHEDAARRYFQQLISAVDYCHSRGVSH 133
Query: 545 RDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFTKYDP 604
RD+K +N +++ G +K+ DFG + + L+ + G+ Y+APEV YD
Sbjct: 134 RDLKPENLLLDENGDLKISDFGLSALPEQILQDGLLHTQ--CGTPAYVAPEVLKKKGYDG 191
Query: 605 RPVDIWSVAILFACMVLKKFPWKIPKLKDNSFKFF 639
DIWS ++ ++ P++ L + K F
Sbjct: 192 AKADIWSCGVVLYVLLAGCLPFQDENLMNMYRKIF 226
>7300650 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 314
Score = 91.7 bits (226), Expect = 4e-18
Identities = 59/199 (29%), Positives = 99/199 (49%), Gaps = 9/199 (4%)
Query: 427 ENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLRHPNII 486
E +G G G V + S Q A+K+ R + E E + E + L+HPN++
Sbjct: 12 EKIGEGTYGIVYKARSNSTGQDVALKKIRLEGETEGVPSTAIR---EISLLKNLKHPNVV 68
Query: 487 STIEIVYENNRIFQVMEYCDYDLFAIVMSNKMSY--EEICCCFKQILTGVEYLHSIGLAH 544
++V N ++ + EY + DL ++ K + + I QIL V + H+ + H
Sbjct: 69 QLFDVVISGNNLYMIFEYLNMDLKKLMDKKKDVFTPQLIKSYMHQILDAVGFCHTNRILH 128
Query: 545 RDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFTKYDP 604
RD+K N +++ G +KL DFG A F+ P E V + Y APE+ + TK+
Sbjct: 129 RDLKPQNLLVDTAGKIKLADFGLARAFNVPMRAYTHE----VVTLWYRAPEILLGTKFYS 184
Query: 605 RPVDIWSVAILFACMVLKK 623
VDIWS+ +F+ M++++
Sbjct: 185 TGVDIWSLGCIFSEMIMRR 203
>Hs7657214 [T] KOG0583 Serine/threonine protein kinase
Length = 714
Score = 91.3 bits (225), Expect = 5e-18
Identities = 64/216 (29%), Positives = 103/216 (47%), Gaps = 20/216 (9%)
Query: 422 YLKTGENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRD-YV-KKITSEYCIGTT 479
YL LG G+ VR + + A+K K +K+D YV K + E I
Sbjct: 61 YLIGSRKLGEGSFAKVREGLHVLTGEKVAIKVIDKK---RAKKDTYVTKNLRREGQIQQM 117
Query: 480 LRHPNIISTIEIVYENNRIFQVMEYCDYD--LFAIVMSNKMSYEEICCCFKQILTGVEYL 537
+RHPNI ++I+ N + VME C + I ++ E +Q+++ VE+L
Sbjct: 118 IRHPNITQLLDILETENSYYLVMELCPGGNLMHKIYEKKRLEESEARRYIRQLISAVEHL 177
Query: 538 HSIGLAHRDMKLDNCVINNQGIVKLIDFGAAEV-----FSYPHSKTLIESSGIVGSDPYL 592
H G+ HRD+K++N +++ +KLIDFG + +S P S GS Y
Sbjct: 178 HRAGVVHRDLKIENLLLDEDNNIKLIDFGLSNCAGILGYSDPFSTQ-------CGSPAYA 230
Query: 593 APEVCIFTKYDPRPVDIWSVAILFACMVLKKFPWKI 628
APE+ KY P+ +D+WS+ + M+ P+ +
Sbjct: 231 APELLARKKYGPK-IDVWSIGVNMYAMLTGTLPFTV 265
>YHL007c [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 939
Score = 90.9 bits (224), Expect = 7e-18
Identities = 60/199 (30%), Positives = 109/199 (54%), Gaps = 11/199 (5%)
Query: 429 LGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLRHPNIIST 488
+G GA G V I N A+K+ E + K++ I +E + +HPNI++
Sbjct: 626 IGQGASGGVYTAYEIGTNVSVAIKQMN--LEKQPKKEL---IINEILVMKGSKHPNIVNF 680
Query: 489 IEIVYENNRIFQVMEYCDYDLFAIVMSNKMSYE-EICCCFKQILTGVEYLHSIGLAHRDM 547
I+ ++ +MEY + V+++ + E +I ++ L+G+E+LHS G+ HRD+
Sbjct: 681 IDSYVLKGDLWVIMEYMEGGSLTDVVTHCILTEGQIGAVCRETLSGLEFLHSKGVLHRDI 740
Query: 548 KLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFTKYDPRPV 607
K DN +++ +G +KL DFG F ++ ++ + +VG+ ++APEV +Y P+ V
Sbjct: 741 KSDNILLSMEGDIKLTDFG----FCAQINELNLKRTTMVGTPYWMAPEVVSRKEYGPK-V 795
Query: 608 DIWSVAILFACMVLKKFPW 626
DIWS+ I+ M+ + P+
Sbjct: 796 DIWSLGIMIIEMIEGEPPY 814
>HsM4505103 [R] KOG0586 Serine/threonine protein kinase
Length = 713
Score = 90.9 bits (224), Expect = 7e-18
Identities = 65/236 (27%), Positives = 110/236 (46%), Gaps = 22/236 (9%)
Query: 404 NDVVYAASHVPALPFSKRYLKTGENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESK 463
N + A P + + R LKT +G G V+L + I + A+K + +
Sbjct: 41 NSIASCADEQPHIG-NYRLLKT---IGKGNFAKVKLARHILTGREVAIKIID---KTQLN 93
Query: 464 RDYVKKITSEYCIGTTLRHPNIISTIEIVYENNRIFQVMEYC------DYDLFAIVMSNK 517
++K+ E I L HPNI+ E++ ++ +MEY DY +V +
Sbjct: 94 PTSLQKLFREVRIMKILNHPNIVKLFEVIETQKTLYLIMEYASGGKVFDY----LVAHGR 149
Query: 518 MSYEEICCCFKQILTGVEYLHSIGLAHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSK 577
M +E F+QI++ V+Y H + HRD+K +N +++ +K+ DFG + F+
Sbjct: 150 MKEKEARSKFRQIVSAVQYCHQKRIVHRDLKAENLLLDADMNIKIADFGFSNEFTVGG-- 207
Query: 578 TLIESSGIVGSDPYLAPEVCIFTKYDPRPVDIWSVAILFACMVLKKFPWKIPKLKD 633
+ GS PY APE+ KYD VD+WS+ ++ +V P+ LK+
Sbjct: 208 ---KLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKE 260
>Hs20986531 [T] KOG0660 Mitogen-activated protein kinase
Length = 360
Score = 90.9 bits (224), Expect = 7e-18
Identities = 80/310 (25%), Positives = 137/310 (43%), Gaps = 35/310 (11%)
Query: 429 LGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLRHPNIIST 488
+G GA G V + A+K+ P FEH++ Y ++ E I RH NII
Sbjct: 31 IGEGAYGMVCSAYDNVNKVRVAIKKISP-FEHQT---YCQRTLREIKILLRFRHENIIGI 86
Query: 489 IEIVY-----ENNRIFQVMEYCDYDLFAIVMSNKMSYEEICCCFKQILTGVEYLHSIGLA 543
+I+ + ++ V + + DL+ ++ + +S + IC QIL G++Y+HS +
Sbjct: 87 NDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQHLSNDHICYFLYQILRGLKYIHSANVL 146
Query: 544 HRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFTKYD 603
HRD+K N ++N +K+ DFG A V H T + V + Y APE+ + +K
Sbjct: 147 HRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTGFLTE-YVATRWYRAPEIMLNSKGY 205
Query: 604 PRPVDIWSVAILFACMVLKK--FPWKIPKLKDNSFKFFCSGRDCDSLSALVTKTPKPPSY 661
+ +DIWSV + A M+ + FP K D L+ ++ P
Sbjct: 206 TKSIDIWSVGCILAEMLSNRPIFPGK---------------HYLDQLNHILGILGSPS-- 248
Query: 662 DNAVQSDEPAESTSKSNN--PSDPNNTNIGPQRLLHSLPEETHHIIGRMVDLAPACRANI 719
Q D K+ N S P+ + RL + + ++ +M+ P R +
Sbjct: 249 ----QEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEV 304
Query: 720 EEVLNDPWIQ 729
E+ L P+++
Sbjct: 305 EQALAHPYLE 314
>At1g29230 [T] KOG0583 Serine/threonine protein kinase
Length = 520
Score = 90.9 bits (224), Expect = 7e-18
Identities = 59/202 (29%), Positives = 96/202 (47%), Gaps = 5/202 (2%)
Query: 426 GENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLRHPNI 485
G+ LG G V L + I A+K E K V I E I +RHP I
Sbjct: 77 GKLLGHGTFAKVYLAQNIKSGDKVAIKVIDK--EKIMKSGLVAHIKREISILRRVRHPYI 134
Query: 486 ISTIEIVYENNRIFQVMEYCDY-DLFAIVMSNKMSYEEICCCFKQILTGVEYLHSIGLAH 544
+ E++ ++I+ VMEY +LF V ++ E F+Q+++ V + H G+ H
Sbjct: 135 VHLFEVMATKSKIYFVMEYVGGGELFNTVAKGRLPEETARRYFQQLISSVSFCHGRGVYH 194
Query: 545 RDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFTKYDP 604
RD+K +N +++N+G +K+ DFG + V L + G+ Y+APEV YD
Sbjct: 195 RDLKPENLLLDNKGNLKVSDFGLSAVAEQLRQDGLCHT--FCGTPAYIAPEVLTRKGYDA 252
Query: 605 RPVDIWSVAILFACMVLKKFPW 626
D+WS ++ ++ P+
Sbjct: 253 AKADVWSCGVILFVLMAGHIPF 274
>7299322 [R] KOG0611 Predicted serine/threonine protein kinase
Length = 434
Score = 90.9 bits (224), Expect = 7e-18
Identities = 63/202 (31%), Positives = 103/202 (50%), Gaps = 9/202 (4%)
Query: 427 ENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLRHPNII 486
+ LG G G V+L Q A+K + K + E++ D V+ I E I +++ HPNII
Sbjct: 86 KKLGQGTYGKVQLGINKETGQEVAIKTIK-KCKIEAEADLVR-IRREVQIMSSVHHPNII 143
Query: 487 STIEIVYENNRIFQVMEYC-DYDLFAIVMSNK-MSYEEICCCFKQILTGVEYLHSIGLAH 544
E+ ++ VME+ +L+ + K ++ EE F+Q+ T V Y H + H
Sbjct: 144 HIYEVFENREKMVLVMEFAAGGELYDYLSERKVLTEEEARRIFRQVATAVYYCHKHKICH 203
Query: 545 RDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFTKYDP 604
RD+KL+N +++ +G K+ DFG + VF + L+ + GS Y +PE+ T Y
Sbjct: 204 RDLKLENILLDEKGNAKIADFGLSNVFD---DQRLLGT--FCGSPLYASPEIVEGTPYQG 258
Query: 605 RPVDIWSVAILFACMVLKKFPW 626
VD WS+ +L +V P+
Sbjct: 259 PEVDCWSLGVLLYTLVYGSMPF 280
>YBR274w [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 527
Score = 90.5 bits (223), Expect = 9e-18
Identities = 72/236 (30%), Positives = 115/236 (48%), Gaps = 11/236 (4%)
Query: 411 SHVPALPFSKRYLKTGENLGAGAGGSVRLMKRISDNQVFAVKEFR--PKFEHESKRDYVK 468
S V LP K + G+ +G GA V+ D + +F P + D K
Sbjct: 4 SQVSPLPHIKDVV-LGDTVGQGAFACVKNAHLQMDPSIILAVKFIHVPTCKKMGLSD--K 60
Query: 469 KITSEYCIGTTL-RHPNIISTIEIVYENNRIFQVMEYCDY-DLFAIVMSNKMSYEEIC-C 525
IT E + + +HPN++ I+ ++ ++E D DLF + + ++
Sbjct: 61 DITKEVVLQSKCSKHPNVLRLIDCNVSKEYMWIILEMADGGDLFDKIEPDVGVDSDVAQF 120
Query: 526 CFKQILTGVEYLH-SIGLAHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSG 584
F+Q+++ + YLH G+AHRD+K +N +++ G +KL DFG A F TL S
Sbjct: 121 YFQQLVSAINYLHVECGVAHRDIKPENILLDKNGNLKLADFGLASQFRRKDG-TLRVSMD 179
Query: 585 IVGSDPYLAPEVCIFTK-YDPRPVDIWSVAILFACMVLKKFPWKIPKLKDNSFKFF 639
GS PY+APEV + Y DIWS+ IL ++ + PW++P L++ F FF
Sbjct: 180 QRGSPPYMAPEVLYSEEGYYADRTDIWSIGILLFVLLTGQTPWELPSLENEDFVFF 235
>Hs21361643 [T] KOG4717 Serine/threonine protein kinase
Length = 765
Score = 90.5 bits (223), Expect = 9e-18
Identities = 78/312 (25%), Positives = 133/312 (42%), Gaps = 64/312 (20%)
Query: 427 ENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKK--ITSEYCIGTTLRHPN 484
+ LG G V+L + + + AVK ++K D + + E ++HPN
Sbjct: 20 KTLGRGHFAVVKLARHVFTGEKVAVKVI-----DKTKLDTLATGHLFQEVRCMKLVQHPN 74
Query: 485 IISTIEIVYENNRIFQVMEYCDY-DLFAIVMSNKMSYEEICC--CFKQILTGVEYLHSIG 541
I+ E++ +++ ++E D D+F +M ++ E F QI+ + Y H +
Sbjct: 75 IVRLYEVIDTQTKLYLILELGDEGDMFDYIMKHEEGLNEDLPKKYFAQIVHAISYCHKLH 134
Query: 542 LAHRDMKLDNCVI-NNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFT 600
+ HRD+K +N V QG+VKL DFG + F K L S G + Y APE+ +
Sbjct: 135 VVHRDLKPENVVFFEKQGLVKLTDFGFSNKFQ--PGKKLTTSCGSLA---YSAPEILLGD 189
Query: 601 KYDPRPVDIWSVAILFACMVLKKFPWKIPKLKDNSFKFFCSGRDCDSLSALVTKTPKPPS 660
+YD VDIWS+ ++ +V + P F D ++L+ ++ PS
Sbjct: 190 EYDAPAVDIWSLGVILFMLVCGQPP-------------FQEANDSETLTMIMDCKYTVPS 236
Query: 661 YDNAVQSDEPAESTSKSNNPSDPNNTNIGPQRLLHSLPEETHHIIGRMVDLAPACRANIE 720
+ + +E +I RM+ P RA++E
Sbjct: 237 H-----------------------------------VSKECKDLITRMLQRDPKRRASLE 261
Query: 721 EVLNDPWIQSID 732
E+ N PW+Q +D
Sbjct: 262 EIENHPWLQGVD 273
>Hs20986529 [T] KOG0660 Mitogen-activated protein kinase
Length = 360
Score = 90.5 bits (223), Expect = 9e-18
Identities = 80/310 (25%), Positives = 136/310 (43%), Gaps = 35/310 (11%)
Query: 429 LGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLRHPNIIST 488
+G GA G V + A+K+ P FEH++ Y ++ E I RH NII
Sbjct: 31 IGEGAYGMVCSAYDNVNKVRVAIKKISP-FEHQT---YCQRTLREIKILLRFRHENIIGI 86
Query: 489 IEIVY-----ENNRIFQVMEYCDYDLFAIVMSNKMSYEEICCCFKQILTGVEYLHSIGLA 543
+I+ + ++ V + + DL+ ++ + +S + IC QIL G++Y+HS +
Sbjct: 87 NDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQHLSNDHICYFLYQILRGLKYIHSANVL 146
Query: 544 HRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFTKYD 603
HRD+K N ++N +K+ DFG A V H T + V + Y APE+ + +K
Sbjct: 147 HRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTGFLTE-YVATRWYRAPEIMLNSKGY 205
Query: 604 PRPVDIWSVAILFACMVLKK--FPWKIPKLKDNSFKFFCSGRDCDSLSALVTKTPKPPSY 661
+ +DIWSV + A M+ + FP K D L ++ P
Sbjct: 206 TKSIDIWSVGCILAEMLSNRPIFPGK---------------HYLDQLKHILGILGSPS-- 248
Query: 662 DNAVQSDEPAESTSKSNN--PSDPNNTNIGPQRLLHSLPEETHHIIGRMVDLAPACRANI 719
Q D K+ N S P+ + RL + + ++ +M+ P R +
Sbjct: 249 ----QEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEV 304
Query: 720 EEVLNDPWIQ 729
E+ L P+++
Sbjct: 305 EQALAHPYLE 314
>CE24971 [T] KOG0660 Mitogen-activated protein kinase
Length = 444
Score = 90.5 bits (223), Expect = 9e-18
Identities = 81/312 (25%), Positives = 137/312 (42%), Gaps = 39/312 (12%)
Query: 429 LGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLRHPNIIST 488
+G GA G V A+K+ P FEH++ + ++ E I +H NII+
Sbjct: 102 IGEGAYGMVASALDTITRDRVAIKKISP-FEHQT---FCQRTLREIKILNRFKHENIINI 157
Query: 489 IEIVYENN-----RIFQVMEYCDYDLFAIVMSNKMSYEEICCCFKQILTGVEYLHSIGLA 543
EI+ I+ V + DL+ ++ + K+S + +C QIL G++Y+HS +
Sbjct: 158 QEIIRSETVDSLKDIYIVQCLMETDLYKLLKTQKLSNDHVCYFLYQILRGLKYIHSANVL 217
Query: 544 HRDMKLDNCVINNQGIVKLIDFGAAEVF--SYPHSKTLIESSGIVGSDPYLAPEVCIFTK 601
HRD+K N ++N +K+ DFG A V H+ L E V + Y APE+ + +K
Sbjct: 218 HRDLKPSNLLLNTTCDLKICDFGLARVTDPQTDHTGFLTE---YVATRWYRAPEIMLNSK 274
Query: 602 YDPRPVDIWSVAILFACMVLKK--FPWKIPKLKDNSFKFFCSGRDCDSLSALVTKTPKPP 659
+ +D+WSV + A M+ + FP K D L+ ++ P
Sbjct: 275 GYTKSIDVWSVGCILAEMLSNRPLFPGK---------------HYLDQLNLILAVVGSPS 319
Query: 660 SYDNAVQSDEPAES--TSKSNNPSDPNNTNIGPQRLLHSLPEETHHIIGRMVDLAPACRA 717
+ D ++ A S S + P P RL ++ +M+ P R
Sbjct: 320 NADLQCIINDKARSYLISLPHKPKQP------WARLYPGADPRALDLLDKMLTFNPHNRI 373
Query: 718 NIEEVLNDPWIQ 729
+IE+ L P+++
Sbjct: 374 DIEQALAHPYLE 385
>CE01583 [T] KOG0660 Mitogen-activated protein kinase
Length = 376
Score = 90.5 bits (223), Expect = 9e-18
Identities = 81/312 (25%), Positives = 137/312 (42%), Gaps = 39/312 (12%)
Query: 429 LGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLRHPNIIST 488
+G GA G V A+K+ P FEH++ + ++ E I +H NII+
Sbjct: 34 IGEGAYGMVASALDTITRDRVAIKKISP-FEHQT---FCQRTLREIKILNRFKHENIINI 89
Query: 489 IEIVYENN-----RIFQVMEYCDYDLFAIVMSNKMSYEEICCCFKQILTGVEYLHSIGLA 543
EI+ I+ V + DL+ ++ + K+S + +C QIL G++Y+HS +
Sbjct: 90 QEIIRSETVDSLKDIYIVQCLMETDLYKLLKTQKLSNDHVCYFLYQILRGLKYIHSANVL 149
Query: 544 HRDMKLDNCVINNQGIVKLIDFGAAEVF--SYPHSKTLIESSGIVGSDPYLAPEVCIFTK 601
HRD+K N ++N +K+ DFG A V H+ L E V + Y APE+ + +K
Sbjct: 150 HRDLKPSNLLLNTTCDLKICDFGLARVTDPQTDHTGFLTE---YVATRWYRAPEIMLNSK 206
Query: 602 YDPRPVDIWSVAILFACMVLKK--FPWKIPKLKDNSFKFFCSGRDCDSLSALVTKTPKPP 659
+ +D+WSV + A M+ + FP K D L+ ++ P
Sbjct: 207 GYTKSIDVWSVGCILAEMLSNRPLFPGK---------------HYLDQLNLILAVVGSPS 251
Query: 660 SYDNAVQSDEPAES--TSKSNNPSDPNNTNIGPQRLLHSLPEETHHIIGRMVDLAPACRA 717
+ D ++ A S S + P P RL ++ +M+ P R
Sbjct: 252 NADLQCIINDKARSYLISLPHKPKQP------WARLYPGADPRALDLLDKMLTFNPHNRI 305
Query: 718 NIEEVLNDPWIQ 729
+IE+ L P+++
Sbjct: 306 DIEQALAHPYLE 317
>At1g01140 [T] KOG0583 Serine/threonine protein kinase
Length = 447
Score = 90.5 bits (223), Expect = 9e-18
Identities = 56/210 (26%), Positives = 103/210 (48%), Gaps = 10/210 (4%)
Query: 426 GENLGAGAGGSVRLMKRISDNQVFAVK--EFRPKFEHESKRDYVKKITSEYCIGTTLRHP 483
G LG G+ V+ K A+K + F H+ V+++ E ++HP
Sbjct: 22 GRTLGEGSFAKVKYAKNTVTGDQAAIKILDREKVFRHKM----VEQLKREISTMKLIKHP 77
Query: 484 NIISTIEIVYENNRIFQVMEYCDY-DLF-AIVMSNKMSYEEICCCFKQILTGVEYLHSIG 541
N++ IE++ +I+ V+E + +LF I ++ +E F+Q++ V+Y HS G
Sbjct: 78 NVVEIIEVMASKTKIYIVLELVNGGELFDKIAQQGRLKEDEARRYFQQLINAVDYCHSRG 137
Query: 542 LAHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFTK 601
+ HRD+K +N +++ G++K+ DFG + L+ ++ G+ Y+APEV
Sbjct: 138 VYHRDLKPENLILDANGVLKVSDFGLSAFSRQVREDGLLHTA--CGTPNYVAPEVLSDKG 195
Query: 602 YDPRPVDIWSVAILFACMVLKKFPWKIPKL 631
YD D+WS ++ ++ P+ P L
Sbjct: 196 YDGAAADVWSCGVILFVLMAGYLPFDEPNL 225
>CE17305 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 375
Score = 90.1 bits (222), Expect = 1e-17
Identities = 59/200 (29%), Positives = 100/200 (49%), Gaps = 19/200 (9%)
Query: 429 LGAGAGGSVRLMKRISDNQVFAVKEFRPKF--EHESKRDYVKKITSEYCIGTTLRHPNII 486
L GA G V + + Q A+K+ + F ++R Y E+ + TTL+HPNII
Sbjct: 35 LNVGAQGIVVMADDLVTTQRVAIKKMQQPFLLTMSARRAY-----REFILLTTLKHPNII 89
Query: 487 STIEIVYENN------RIFQVMEYCDYDLFAIVMSNKMSYEEICCCFKQILTGVEYLHSI 540
+ + ++ VME+ ++L ++ ++ +E + Q L +++LH++
Sbjct: 90 RLLNAFTPDTSLSSFQEVYLVMEFMTHNLHEVIHRLRLDHETLSFLVYQSLCAIKHLHNL 149
Query: 541 GLAHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFT 600
G HRD+K N V+N + ++K++DFG A + S VG+ Y APEV +
Sbjct: 150 GFIHRDLKPSNIVVNERCVLKVLDFGLAR-----RRNVDMRMSDYVGTRYYRAPEVILGL 204
Query: 601 KYDPRPVDIWSVAILFACMV 620
Y + VDIWSV + A M+
Sbjct: 205 NYSEK-VDIWSVGCILAEMI 223
>CE12408 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 527
Score = 90.1 bits (222), Expect = 1e-17
Identities = 61/200 (30%), Positives = 100/200 (49%), Gaps = 14/200 (7%)
Query: 421 RYLKTGENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTL 480
RYL T + LG G G V L K+I A+K + KF + ++++ S L
Sbjct: 44 RYLMT-KRLGDGTFGEVMLAKKIDTGDRVAIKRMKKKFYSWEEAMSLREVKSL----KKL 98
Query: 481 RHPNIISTIEIVYENNRIFQVMEYCDYDLFAIVMSNKMSYEE--ICCCFKQILTGVEYLH 538
HPNII E++ EN+ ++ V E+ +L+ ++ + E I Q+L G+ ++H
Sbjct: 99 NHPNIIKLREVIRENDILYFVFEFMQENLYELMKDRDRYFPESVIRNIIYQVLQGLAFMH 158
Query: 539 SIGLAHRDMKLDNCVINNQGIVKLIDFG-AAEVFSYPHSKTLIESSGIVGSDPYLAPEVC 597
G HRDMK +N + N +VK+ DFG A E+ S P + V + Y APE+
Sbjct: 159 KNGFFHRDMKPENIMCNGTELVKIADFGLAREIRSKP------PYTDYVSTRWYRAPEIL 212
Query: 598 IFTKYDPRPVDIWSVAILFA 617
+ + P+D+W++ + A
Sbjct: 213 LRSTSYNSPIDMWALGCIMA 232
>At4g30960 [T] KOG0583 Serine/threonine protein kinase
Length = 441
Score = 90.1 bits (222), Expect = 1e-17
Identities = 82/309 (26%), Positives = 138/309 (44%), Gaps = 25/309 (8%)
Query: 426 GENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLRHPNI 485
G LG G V + I + A+K E K V +I E + ++HPNI
Sbjct: 27 GRLLGHGTFAKVYHARNIQTGKSVAMKVVGK--EKVVKVGMVDQIKREISVMRMVKHPNI 84
Query: 486 ISTIEIVYENNRIFQVMEYC-DYDLFAIVMSNKMSYEEICCCFKQILTGVEYLHSIGLAH 544
+ E++ ++I+ ME +LFA V ++ + F+Q+++ V++ HS G+ H
Sbjct: 85 VELHEVMASKSKIYFAMELVRGGELFAKVAKGRLREDVARVYFQQLISAVDFCHSRGVYH 144
Query: 545 RDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFTKYDP 604
RD+K +N +++ +G +K+ DFG + + L+ ++ G+ Y+APEV + YD
Sbjct: 145 RDLKPENLLLDEEGNLKVTDFGLSAFTEHLKQDGLLHTT--CGTPAYVAPEVILKKGYDG 202
Query: 605 RPVDIWSVAILFACMVLKKFPWKIPKLKDNSFK-----FFCSGRDCDSLSALVTKTPKP- 658
D+WS ++ ++ P++ L + K F C G LVTK P
Sbjct: 203 AKADLWSCGVILFVLLAGYLPFQDDNLVNMYRKIYRGDFKCPGWLSSDARRLVTKLLDPN 262
Query: 659 PSYDNAVQS--DEP---AESTSKSNNP--SDPNNTNIGPQRLLHSLPEETH-----HII- 705
P+ ++ D P ++T N P + T L+H EET HII
Sbjct: 263 PNTRITIEKVMDSPWFKKQATRSRNEPVAATITTTEEDVDFLVHKSKEETETLNAFHIIA 322
Query: 706 -GRMVDLAP 713
DL+P
Sbjct: 323 LSEGFDLSP 331
>At4g29810 [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K)
Length = 363
Score = 90.1 bits (222), Expect = 1e-17
Identities = 71/270 (26%), Positives = 130/270 (47%), Gaps = 21/270 (7%)
Query: 429 LGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLRHPNIIST 488
+G G+ G V+L++ Q FA+K + + + K I E I + + PN++++
Sbjct: 76 IGKGSSGVVQLVQHKWTGQFFALKVIQLNIDEAIR----KAIAQELKINQSSQCPNLVTS 131
Query: 489 IEIVYENNRIFQVMEYCDYDLFAIVMSNKMSYEE--ICCCFKQILTGVEYLH-SIGLAHR 545
+ Y+N I ++EY D A + + + + + F+Q+L G+ YLH + HR
Sbjct: 132 YQSFYDNGAISLILEYMDGGSLADFLKSVKAIPDSYLSAIFRQVLQGLIYLHHDRHIIHR 191
Query: 546 DMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFTKYDPR 605
D+K N +IN++G VK+ DFG + V + T ++ VG+ Y++PE + KY +
Sbjct: 192 DLKPSNLLINHRGEVKITDFGVSTVM----TNTAGLANTFVGTYNYMSPERIVGNKYGNK 247
Query: 606 PVDIWSVAILFACMVLKKFPWKIPKLKDNSFKFFCSGRDCDSLSALVTKTPKPPSYDNAV 665
DIWS+ ++ KFP+ P ++ F + + A+V + PP+ +
Sbjct: 248 S-DIWSLGLVVLECATGKFPYAPPNQEETWTSVF------ELMEAIVDQ--PPPALPSGN 298
Query: 666 QSDEPAESTSKSNNPSDPNNTNIGPQRLLH 695
S E + S DPN+ + + + H
Sbjct: 299 FSPELSSFISTCLQ-KDPNSRSSAKELMEH 327
>At2g26980 [T] KOG0583 Serine/threonine protein kinase
Length = 441
Score = 90.1 bits (222), Expect = 1e-17
Identities = 60/221 (27%), Positives = 106/221 (47%), Gaps = 7/221 (3%)
Query: 424 KTGENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLRHP 483
+ G +G G V+ + + A+K E K ++I E ++HP
Sbjct: 15 EVGRTIGEGTFAKVKFARNSETGEPVALKILDK--EKVLKHKMAEQIRREIATMKLIKHP 72
Query: 484 NIISTIEIVYENNRIFQVMEYCDY-DLF-AIVMSNKMSYEEICCCFKQILTGVEYLHSIG 541
N++ E++ +IF ++EY +LF IV +M +E F+Q++ V+Y HS G
Sbjct: 73 NVVQLYEVMASKTKIFIILEYVTGGELFDKIVNDGRMKEDEARRYFQQLIHAVDYCHSRG 132
Query: 542 LAHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFTK 601
+ HRD+K +N ++++ G +K+ DFG + + L+ +S G+ Y+APEV
Sbjct: 133 VYHRDLKPENLLLDSYGNLKISDFGLSALSQQVRDDGLLHTS--CGTPNYVAPEVLNDRG 190
Query: 602 YDPRPVDIWSVAILFACMVLKKFPWKIPKLKDNSFKFFCSG 642
YD D+WS ++ ++ P+ L N +K SG
Sbjct: 191 YDGATADMWSCGVVLYVLLAGYLPFDDSNLM-NLYKKISSG 230
>7299437 [R] KOG0586 Serine/threonine protein kinase
Length = 604
Score = 90.1 bits (222), Expect = 1e-17
Identities = 60/209 (28%), Positives = 103/209 (48%), Gaps = 10/209 (4%)
Query: 427 ENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLRHPNII 486
+ LG G V+L + + A+K + R +K+ E I L HPNI+
Sbjct: 67 KTLGKGNFAKVKLAIHLPTGREVAIKLIDKTALNTIAR---QKLYREVNIMKKLNHPNIV 123
Query: 487 STIEIVYENNRIFQVMEYCDY-DLFAIVMSN-KMSYEEICCCFKQILTGVEYLHSIGLAH 544
++++ ++ VMEY +LF ++ N +M + F+Q+++ +EY HS + H
Sbjct: 124 RLLQVIESERTLYLVMEYVSGGELFNYLVKNGRMRERDARVLFRQLVSAIEYCHSKSIVH 183
Query: 545 RDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFTKYDP 604
RD+K +N +++ Q +K+ DFG + F K +E+ GS PY APE+ KY
Sbjct: 184 RDLKAENLLLDQQMKLKIADFGFSTTF---EPKAPLET--FCGSPPYAAPELFRGKKYSG 238
Query: 605 RPVDIWSVAILFACMVLKKFPWKIPKLKD 633
VD WS+ ++ +V P+ LK+
Sbjct: 239 PEVDSWSLGVVLYTLVSGSLPFDGTNLKE 267
>CE26793_1 [R] KOG0611 Predicted serine/threonine protein kinase
Length = 795
Score = 90.1 bits (222), Expect = 1e-17
Identities = 69/211 (32%), Positives = 100/211 (46%), Gaps = 13/211 (6%)
Query: 420 KRYLKTGENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTT 479
K + + LG+G G V L ++ AVK + K ESK D V+ I E I +
Sbjct: 72 KHRFEITKKLGSGTYGKVSLAYDHKFDREVAVKLIK-KSAIESKADLVR-IRREIRIMSA 129
Query: 480 LRHPNIISTIEIVYENNRIFQVMEYCD----YDLFAIVMSNKMSYEEICCCFKQILTGVE 535
L HPNII E+ ++I VMEY YD + + E F+QI + V
Sbjct: 130 LNHPNIIQIYEVFENKDKIILVMEYSSGGELYDY--VSRCGSLPEAEARRIFRQITSAVL 187
Query: 536 YLHSIGLAHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPE 595
Y H +AHRD+KL+N +++ K+ DFG + F+ K L+ + GS Y +PE
Sbjct: 188 YCHKHRVAHRDLKLENILLDQNNNAKIADFGLSNYFA---DKNLLTT--FCGSPLYASPE 242
Query: 596 VCIFTKYDPRPVDIWSVAILFACMVLKKFPW 626
+ T Y VD WS+ IL +V P+
Sbjct: 243 IINGTPYKGPEVDCWSLGILLYTLVYGSMPF 273
>CE28479 [T] KOG0583 Serine/threonine protein kinase
Length = 822
Score = 89.7 bits (221), Expect = 2e-17
Identities = 61/212 (28%), Positives = 103/212 (47%), Gaps = 13/212 (6%)
Query: 426 GENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLRHPNI 485
G +G G +VR+ + A+K R+ + K+ E I + HP+I
Sbjct: 19 GRAIGKGNFATVRIARHKIAKTKVAIKSIDVS---ALDRENLIKLEREVKIVKVIDHPHI 75
Query: 486 ISTIEIVYENNRIFQVMEYCDY-DLFAIVMSNKMSYEEICC-CFKQILTGVEYLHSIGLA 543
+ + EI+ +N ++ V EYC +L+ ++ E + F + + V YLHS G+
Sbjct: 76 VKSYEIMRVDNMLYIVSEYCSSGELYETLIEKGRVAENVARKWFSETASAVAYLHSQGIV 135
Query: 544 HRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFTKYD 603
HRD+K +N ++ +K+IDFG + ++ L+ + GS PY APE+ + YD
Sbjct: 136 HRDLKAENILLGKNSNIKIIDFGFS---NFQTGDQLLNT--WCGSPPYAAPELLLGNSYD 190
Query: 604 PRPVDIWSVAILFACMVLKKFPW---KIPKLK 632
DIWS+ +L +V FP+ + KLK
Sbjct: 191 GMKADIWSMGVLLYILVAGGFPFPSDSVNKLK 222
>At1g51660 [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K)
Length = 366
Score = 89.7 bits (221), Expect = 2e-17
Identities = 75/287 (26%), Positives = 133/287 (46%), Gaps = 23/287 (8%)
Query: 423 LKTGENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLRH 482
L G +G+GAGG+V + ++++A+K E +R ++I I + H
Sbjct: 79 LVRGNRIGSGAGGTVYKVIHRPSSRLYALKVIYGNHEETVRRQICREIE----ILRDVNH 134
Query: 483 PNIISTIEIVYENNRIFQVMEYCDYDLFAIVMSNKMSYEEICCCFKQILTGVEYLHSIGL 542
PN++ E+ +N I ++E+ D ++ ++ +++ +QIL+G+ YLHS +
Sbjct: 135 PNVVKCHEMFDQNGEIQVLLEFMDKG--SLEGAHVWKEQQLADLSRQILSGLAYLHSRHI 192
Query: 543 AHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFT-- 600
HRD+K N +IN+ VK+ DFG + + ++T+ + VG+ Y++PE I T
Sbjct: 193 VHRDIKPSNLLINSAKNVKIADFGVSRIL----AQTMDPCNSSVGTIAYMSPE-RINTDL 247
Query: 601 ---KYDPRPVDIWSVAILFACMVLKKFPWKIPKLKDNSFKFFCSGRDCDSLSALVTKTPK 657
KYD DIWS+ + L +FP+ + + D + C+ A T +P+
Sbjct: 248 NQGKYDGYAGDIWSLGVSILEFYLGRFPFPVSRQGDWA-SLMCAICMSQPPEAPATASPE 306
Query: 658 PPSYDNAVQSDEPAESTSKSNNPSDP------NNTNIGPQRLLHSLP 698
+ + EP + S P + N PQ L LP
Sbjct: 307 FRHFISCCLQREPGKRRSAMQLLQHPFILRASPSQNRSPQNLHQLLP 353
>YAL017w [T] KOG1152 Signal transduction serine/threonine kinase with PAS/PAC
sensor domain
Length = 1356
Score = 89.4 bits (220), Expect = 2e-17
Identities = 77/256 (30%), Positives = 127/256 (49%), Gaps = 27/256 (10%)
Query: 427 ENLGAGAGGSVRLMKRISDNQVFAVKE-FRPKFEHES--KRDYVKKITSEYCIGTTLR-- 481
+ +G GA G V L + + +K F+ + ++ + + I SE I TL
Sbjct: 1100 QKMGEGAYGKVNLCIHKKNRYIVVIKMIFKERILVDTWVRDRKLGTIPSEIQIMATLNKK 1159
Query: 482 -HPNIISTIEIVYENNRIFQVM-----EYCDYDLFAIV-MSNKMSYEEICCCFKQILTGV 534
H NI+ ++ +E++ + + E DLF ++ M+ E FKQ++ G+
Sbjct: 1160 PHENILRLLDF-FEDDDYYYIETPVHGETGCIDLFDLIEFKTNMTEFEAKLIFKQVVAGI 1218
Query: 535 EYLHSIGLAHRDMKLDNCVINNQGIVKLIDFG-AAEVFSYPHSKTLIESSGIVGSDPYLA 593
++LH G+ HRD+K +N +++++G VK+IDFG AA V S P VG+ Y A
Sbjct: 1219 KHLHDQGIVHRDIKDENVIVDSKGFVKIIDFGSAAYVKSGPFDV-------FVGTIDYAA 1271
Query: 594 PEVCIFTKYDPRPVDIWSVAILFACMVLKKFP-WKIPKLKDNSFKFFCS---GRDCDSL- 648
PEV Y+ +P DIW++ IL +V K+ P + I ++ + KF + DC L
Sbjct: 1272 PEVLGGNPYEGQPQDIWAIGILLYTVVFKENPFYNIDEILEGDLKFNNAEEVSEDCIELI 1331
Query: 649 -SALVTKTPKPPSYDN 663
S L PK P+ D+
Sbjct: 1332 KSILNRCVPKRPTIDD 1347
>SPCC74.03c [T] KOG0583 Serine/threonine protein kinase
Length = 576
Score = 89.4 bits (220), Expect = 2e-17
Identities = 64/218 (29%), Positives = 107/218 (48%), Gaps = 11/218 (5%)
Query: 413 VPALPFSKRYLKT---GENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKK 469
+P SKR++ E LG G+ G V+L Q A+K + +S D +
Sbjct: 21 LPPEAISKRHIGPYIIRETLGEGSFGKVKLATHYKTQQKVALKFISRQLLKKS--DMHMR 78
Query: 470 ITSEYCIGTTLRHPNIISTIEIVYENNRIFQVMEYCDYDLFAIVMSNK-MSYEEICCCFK 528
+ E LRHP+II +++ I V+EY +LF ++ K M+ +E F+
Sbjct: 79 VEREISYLKLLRHPHIIKLYDVITTPTDIVMVIEYAGGELFDYIVEKKRMTEDEGRRFFQ 138
Query: 529 QILTGVEYLHSIGLAHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGS 588
QI+ +EY H + HRD+K +N ++++ VK+ DFG + + + +++S GS
Sbjct: 139 QIICAIEYCHRHKIVHRDLKPENLLLDDNLNVKIADFGLSNIMT---DGNFLKTS--CGS 193
Query: 589 DPYLAPEVCIFTKYDPRPVDIWSVAILFACMVLKKFPW 626
Y APEV Y VD+WS I+ M++ + P+
Sbjct: 194 PNYAAPEVINGKLYAGPEVDVWSCGIVLYVMLVGRLPF 231
>SPCC297.03 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kinase beta
and related serine/threonine protein kinases
Length = 652
Score = 89.4 bits (220), Expect = 2e-17
Identities = 58/221 (26%), Positives = 107/221 (48%), Gaps = 27/221 (12%)
Query: 427 ENLGAGAGGSVRLMKRISDNQVFAVK-----EFRPKFEHESKRDYVKKITSEYCIGTTLR 481
+ LG G G V+L + ++ A+K E RPK + +K+ E I
Sbjct: 139 KELGRGMHGKVKLGRDTVTRELLAIKIIPKTERRPKLGRANASSQKEKVRREIAILKKCV 198
Query: 482 HPNIISTIEIVYE--NNRIFQVMEYC--------DYDLFAIVMSNKMSYEEICCCFKQIL 531
HPN++ E++ + + +++ V+EY D D + +S Y F+ ++
Sbjct: 199 HPNVVRLREVIDDPSSTKVYLVLEYMSGGEVPWTDCDSPVLSISEARQY------FRDVV 252
Query: 532 TGVEYLHSIGLAHRDMKLDNCVINNQGIVKLIDFGAAEVFSYP-HSKTLIESSGIVGSDP 590
G+EYLH G+ HRD+K N ++N+ VK+ DFG + + + + +E + VG+
Sbjct: 253 LGLEYLHYQGIIHRDIKPANLLLNSSNCVKISDFGVSYIANAGLNEDNDVELAKTVGTPA 312
Query: 591 YLAPEVCIFTKYDPRP-----VDIWSVAILFACMVLKKFPW 626
+ APE+C PRP +D+W++ + C++ + P+
Sbjct: 313 FFAPELCWTDLDRPRPKISEAIDVWALGVTLFCLLFGRCPF 353
>Hs7661974 [T] KOG0583 Serine/threonine protein kinase
Length = 651
Score = 89.4 bits (220), Expect = 2e-17
Identities = 62/208 (29%), Positives = 102/208 (48%), Gaps = 9/208 (4%)
Query: 421 RYLKTGENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTL 480
+Y + E +G G V+L I ++ A+K + + + +I +E L
Sbjct: 9 KYYELHETIGTGGFAKVKLACHILTGEMVAIKIM----DKNTLGSDLPRIKTEIEALKNL 64
Query: 481 RHPNIISTIEIVYENNRIFQVMEYCDY-DLFAIVMS-NKMSYEEICCCFKQILTGVEYLH 538
RH +I ++ N+IF V+EYC +LF ++S +++S EE F+QI++ V Y+H
Sbjct: 65 RHQHICQLYHVLETANKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQIVSAVAYVH 124
Query: 539 SIGLAHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCI 598
S G AHRD+K +N + + +KLIDFG + + P GS Y APE+
Sbjct: 125 SQGYAHRDLKPENLLFDEYHKLKLIDFG---LCAKPKGNKDYHLQTCCGSLAYAAPELIQ 181
Query: 599 FTKYDPRPVDIWSVAILFACMVLKKFPW 626
Y D+WS+ IL ++ P+
Sbjct: 182 GKSYLGSEADVWSMGILLYVLMCGFLPF 209
>At5g45810 [T] KOG0583 Serine/threonine protein kinase
Length = 483
Score = 89.4 bits (220), Expect = 2e-17
Identities = 59/202 (29%), Positives = 95/202 (46%), Gaps = 5/202 (2%)
Query: 426 GENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLRHPNI 485
G LG G V L + + A+K E K + I E I +RHPNI
Sbjct: 31 GRLLGHGTFAKVYLARNAQSGESVAIKVIDK--EKVLKSGLIAHIKREISILRRVRHPNI 88
Query: 486 ISTIEIVYENNRIFQVMEYCDY-DLFAIVMSNKMSYEEICCCFKQILTGVEYLHSIGLAH 544
+ E++ ++I+ VMEY +LF V ++ E F+Q+++ V + H G+ H
Sbjct: 89 VQLFEVMATKSKIYFVMEYVKGGELFNKVAKGRLKEEMARKYFQQLISAVSFCHFRGVYH 148
Query: 545 RDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFTKYDP 604
RD+K +N +++ G +K+ DFG + V L + G+ Y+APEV YD
Sbjct: 149 RDLKPENLLLDENGNLKVSDFGLSAVSDQIRQDGLFHT--FCGTPAYVAPEVLARKGYDG 206
Query: 605 RPVDIWSVAILFACMVLKKFPW 626
VDIWS ++ ++ P+
Sbjct: 207 AKVDIWSCGVILFVLMAGFLPF 228
>At3g29160 [T] KOG0583 Serine/threonine protein kinase
Length = 512
Score = 89.4 bits (220), Expect = 2e-17
Identities = 65/214 (30%), Positives = 109/214 (50%), Gaps = 14/214 (6%)
Query: 424 KTGENLGAGAGGSVRLMKRISDNQVFAVKEF-RPKFEHESKRDYVKKITSEYCIGTTLRH 482
K G+ LG G+ G V++ + + A+K R K ++ + V++ E I H
Sbjct: 21 KLGKTLGIGSFGKVKIAEHVVTGHKVAIKILNRRKIKNMEMEEKVRR---EIKILRLFMH 77
Query: 483 PNIISTIEIVYENNRIFQVMEYCDY-DLFA-IVMSNKMSYEEICCCFKQILTGVEYLHSI 540
P+II E++ + I+ VMEY +LF IV ++ +E F+QI++GVEY H
Sbjct: 78 PHIIRQYEVIETTSDIYVVMEYVKSGELFDYIVEKGRLQEDEARNFFQQIISGVEYCHRN 137
Query: 541 GLAHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFT 600
+ HRD+K +N +++++ +K+ DFG + V H +++S GS Y APEV
Sbjct: 138 MVVHRDLKPENLLLDSRCNIKIADFGLSNVMRDGH---FLKTS--CGSPNYAAPEVISGK 192
Query: 601 KYDPRPVDIWSVAILFACMVLKKFPW---KIPKL 631
Y VD+WS ++ ++ P+ IP L
Sbjct: 193 LYAGPEVDVWSCGVILYALLCGTLPFDDENIPNL 226
>At1g78290 [T] KOG0583 Serine/threonine protein kinase
Length = 343
Score = 89.4 bits (220), Expect = 2e-17
Identities = 64/208 (30%), Positives = 107/208 (50%), Gaps = 17/208 (8%)
Query: 427 ENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLRHPNII 486
+++G+G G +L++ ++FAVK E K D + + E +L HPNII
Sbjct: 8 KDIGSGNFGVAKLVRDKFSKELFAVKFI----ERGQKID--EHVQREIMNHRSLIHPNII 61
Query: 487 STIEIVYENNRIFQVMEYC-DYDLFAIVMS-NKMSYEEICCCFKQILTGVEYLHSIGLAH 544
E++ + VMEY +LF + S + S +E F+Q+++GV Y HS+ + H
Sbjct: 62 RFKEVLLTATHLALVMEYAAGGELFGRICSAGRFSEDEARFFFQQLISGVNYCHSLQICH 121
Query: 545 RDMKLDNCVINNQGI--VKLIDFGAAEVFSYPHSKTL-IESSGIVGSDPYLAPEVCIFTK 601
RD+KL+N +++ VK+ DFG Y S L + VG+ Y+APEV +
Sbjct: 122 RDLKLENTLLDGSEAPRVKICDFG------YSKSGVLHSQPKTTVGTPAYIAPEVLSTKE 175
Query: 602 YDPRPVDIWSVAILFACMVLKKFPWKIP 629
YD + D+WS + M++ +P++ P
Sbjct: 176 YDGKIADVWSCGVTLYVMLVGAYPFEDP 203
>At1g54960 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 585
Score = 89.4 bits (220), Expect = 2e-17
Identities = 59/208 (28%), Positives = 106/208 (50%), Gaps = 8/208 (3%)
Query: 424 KTGENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRD---YVKKITSEYCIGTTL 480
+ G+ +G GA G+V + + ++ AVK+ SK +++++ E + L
Sbjct: 69 RKGQLIGRGAFGTVYMGMNLDSGELLAVKQVLITSNCASKEKTQAHIQELEEEVKLLKNL 128
Query: 481 RHPNIISTIEIVYENNRIFQVMEYCDYDLFAIVMSNKMSYEE--ICCCFKQILTGVEYLH 538
HPNI+ + V E+ + ++E+ + ++ ++ E + Q+L G+EYLH
Sbjct: 129 SHPNIVRYLGTVREDETLNILLEFVPGGSISSLLEKFGAFPESVVRTYTNQLLLGLEYLH 188
Query: 539 SIGLAHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCI 598
+ + HRD+K N +++NQG +KL DFGA++ T+ + + G+ ++APEV +
Sbjct: 189 NHAIMHRDIKGANILVDNQGCIKLADFGASK--QVAELATISGAKSMKGTPYWMAPEVIL 246
Query: 599 FTKYDPRPVDIWSVAILFACMVLKKFPW 626
T + DIWSV MV K PW
Sbjct: 247 QTGHS-FSADIWSVGCTVIEMVTGKAPW 273
>At1g09000 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 666
Score = 89.4 bits (220), Expect = 2e-17
Identities = 58/208 (27%), Positives = 107/208 (50%), Gaps = 8/208 (3%)
Query: 424 KTGENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRD---YVKKITSEYCIGTTL 480
+ G+ +G GA G+V + + ++ AVK+ SK +++++ E + L
Sbjct: 70 RKGQLIGRGAFGTVYMGMNLDSGELLAVKQVLIAANFASKEKTQAHIQELEEEVKLLKNL 129
Query: 481 RHPNIISTIEIVYENNRIFQVMEYCDYDLFAIVMSNKMSYEE--ICCCFKQILTGVEYLH 538
HPNI+ + V E++ + ++E+ + ++ + E + +Q+L G+EYLH
Sbjct: 130 SHPNIVRYLGTVREDDTLNILLEFVPGGSISSLLEKFGPFPESVVRTYTRQLLLGLEYLH 189
Query: 539 SIGLAHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCI 598
+ + HRD+K N +++N+G +KL DFGA++ T+ + + G+ ++APEV +
Sbjct: 190 NHAIMHRDIKGANILVDNKGCIKLADFGASK--QVAELATMTGAKSMKGTPYWMAPEVIL 247
Query: 599 FTKYDPRPVDIWSVAILFACMVLKKFPW 626
T + DIWSV MV K PW
Sbjct: 248 QTGHS-FSADIWSVGCTVIEMVTGKAPW 274
>SPBC4F6.06 [T] KOG0583 Serine/threonine protein kinase
Length = 891
Score = 89.0 bits (219), Expect = 3e-17
Identities = 78/325 (24%), Positives = 131/325 (40%), Gaps = 79/325 (24%)
Query: 426 GENLGAGAGGSVRLMKRISDNQVFAVK---EFRPKFEH-------------ESKRDYVKK 469
G+ +GAG+ G V++ + + FA+K P +S+++ +
Sbjct: 128 GKTIGAGSMGKVKVAHHLKTGEQFAIKIVTRLHPDITKAKAAASAEATKAAQSEKNKEIR 187
Query: 470 ITSEYCIGTTLRHPNIISTIEIVYENNRIFQVMEYCDYD--LFAIVMSNKMSYEEICCCF 527
E + T LRHP I ++ N+ + V E+ D L I+ K+ ++
Sbjct: 188 TVREAALSTLLRHPYICEARDVYITNSHYYMVFEFVDGGQMLDYIISHGKLKEKQARKFV 247
Query: 528 KQILTGVEYLHSIGLAHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVG 587
+QI + + YLH + HRD+K++N +I+ G +K+IDFG + ++ + G
Sbjct: 248 RQIGSALSYLHQNSVVHRDLKIENILISKTGDIKIIDFGLSNLY-----RRQSRLRTFCG 302
Query: 588 SDPYLAPEVCIFTKYDPRPVDIWSVAILFACMVLKKFPWKIPKLKDNSFKFFCSGRDCDS 647
S + APE+ Y VD+WS I+ +V K P+ D +
Sbjct: 303 SLYFAAPELLNAQPYIGPEVDVWSFGIVLYVLVCGKVPF-----------------DDQN 345
Query: 648 LSALVTK----TPKPPSYDNAVQSDEPAESTSKSNNPSDPNNTNIGPQRLLHSLPEETHH 703
+SAL K T + PSY L +
Sbjct: 346 MSALHAKIKKGTVEYPSY-----------------------------------LSSDCKG 370
Query: 704 IIGRMVDLAPACRANIEEVLNDPWI 728
++ RM+ P RA +EEVLN PW+
Sbjct: 371 LLSRMLVTDPLKRATLEEVLNHPWM 395
>SPBC32H8.10 [D] KOG0600 Cdc2-related protein kinase
Length = 591
Score = 89.0 bits (219), Expect = 3e-17
Identities = 65/212 (30%), Positives = 103/212 (47%), Gaps = 22/212 (10%)
Query: 427 ENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLRHPNII 486
E LG G G V +R D +V+A+K H K + E I +++H NII
Sbjct: 40 EKLGEGTFGEVYKSQRRKDGKVYALKRI---LMHTEKEGFPITAIREIKILKSIKHENII 96
Query: 487 --STIEIVYENNR------IFQVMEYCDYDLFAIVMSNKMSYEE--ICCCFKQILTGVEY 536
S + +V + + I+ V Y D+DL ++ + + + E I C KQ+ G +Y
Sbjct: 97 PLSDMTVVRADKKHRRRGSIYMVTPYMDHDLSGLLENPSVKFTEPQIKCYMKQLFAGTKY 156
Query: 537 LHSIGLAHRDMKLDNCVINNQGIVKLIDFGAAEVF---SYPHSKTLI------ESSGIVG 587
LH + HRD+K N +I+N GI+K+ DFG A V SY + + E +G V
Sbjct: 157 LHDQLILHRDLKAANLLIDNHGILKIADFGLARVITEESYANKNPGLPPPNRREYTGCVV 216
Query: 588 SDPYLAPEVCIFTKYDPRPVDIWSVAILFACM 619
+ Y +PE+ + + +D+WSV + A M
Sbjct: 217 TRWYRSPELLLGERRYTTAIDMWSVGCIMAEM 248
>Hs11496279 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 623
Score = 89.0 bits (219), Expect = 3e-17
Identities = 78/308 (25%), Positives = 131/308 (42%), Gaps = 31/308 (10%)
Query: 425 TGENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLRHPN 484
T LG G GSV + K ++ A+K + KF + ++++ S L H N
Sbjct: 6 TMRQLGDGTYGSVLMGKSNESGELVAIKRMKRKFYSWDECMNLREVKSL----KKLNHAN 61
Query: 485 IISTIEIVYENNRIFQVMEYCDYDLFAIVMSNKMSYEE--ICCCFKQILTGVEYLHSIGL 542
+I E++ EN+ ++ + EY +L+ ++ + E I QIL G+ ++H G
Sbjct: 62 VIKLKEVIRENDHLYFIFEYMKENLYQLMKDRNKLFPESVIRNIMYQILQGLAFIHKHGF 121
Query: 543 AHRDMKLDNCVINNQGIVKLIDFG-AAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFTK 601
HRDMK +N + +VK+ DFG A E+ S P + V + Y APEV + +
Sbjct: 122 FHRDMKPENLLCMGPELVKIADFGLARELRSQP------PYTDYVSTRWYRAPEVLLRSS 175
Query: 602 YDPRPVDIWSVAILFACMVLKKFPWKIPKLKDNSFKFFCSGRDCDSLSALVTKTPKPPSY 661
P+D+W+V + A + + + + D FK C L TPK +
Sbjct: 176 VYSSPIDVWAVGSIMAELYMLRPLFPGTSEVDEIFKI------CQVLG-----TPKKSDW 224
Query: 662 DNAVQSDEPAESTSKSNNPSDPNNTNIGPQRLLHSLPEETHHIIGRMVDLAPACRANIEE 721
Q + S N P I + L+ + E ++ M++ P R +
Sbjct: 225 PEGYQ-------LASSMNFRFPQCVPINLKTLIPNASNEAIQLMTEMLNWDPKKRPTASQ 277
Query: 722 VLNDPWIQ 729
L P+ Q
Sbjct: 278 ALKHPYFQ 285
>At1g73690 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 398
Score = 89.0 bits (219), Expect = 3e-17
Identities = 86/314 (27%), Positives = 137/314 (43%), Gaps = 34/314 (10%)
Query: 421 RYLKTGENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTL 480
RYLK E LG G G V + + A+K+ R E E + E + L
Sbjct: 10 RYLKR-EVLGQGTYGVVFKATDTKNGETVAIKKIRLGKEKEGVNVTALR---EIKLLKEL 65
Query: 481 RHPNIISTIEIVYENNRIFQVMEYCDYDLFAIVMSNKM--SYEEICCCFKQILTGVEYLH 538
+HP+II I+ + V E+ + DL A++ + S ++ + IL G+EY H
Sbjct: 66 KHPHIIELIDAFPHKENLHIVFEFMETDLEAVIRDRNLYLSPGDVKSYLQMILKGLEYCH 125
Query: 539 SIGLAHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCI 598
+ HRDMK +N +I G +KL DFG A +F P K + V + Y APE+
Sbjct: 126 GKWVLHRDMKPNNLLIGPNGQLKLADFGLARIFGSPGRKFTHQ----VFARWYRAPELLF 181
Query: 599 FTKYDPRPVDIWSVAILFACMVLKKFPWKIPKLKDNSFKFFCSGRDCDSLSALVTK--TP 656
K VD+W+ +FA ++L++ P L+ NS D D LS + TP
Sbjct: 182 GAKQYDGAVDVWAAGCIFAELLLRR-----PFLQGNS--------DIDQLSKIFAAFGTP 228
Query: 657 KPPSYDNAVQSDEPAESTSKSNNPSDPNNTNIGPQRLLHSLPEETHHIIGRMVDLAPACR 716
K + + + + E PS + LL ++ E+ ++ +M P R
Sbjct: 229 KADQWPDMICLPDYVEYQFVP-APS--------LRSLLPTVSEDALDLLSKMFTYDPKSR 279
Query: 717 ANIEEVLNDPWIQS 730
+I++ L + S
Sbjct: 280 ISIQQALKHRYFTS 293
>SPAC23C11.16 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 683
Score = 88.6 bits (218), Expect = 3e-17
Identities = 75/284 (26%), Positives = 129/284 (45%), Gaps = 34/284 (11%)
Query: 432 GAGGSVRLMKRISDN--QVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLRHPNIISTI 489
G GG R R+ DN ++A K + K K+ E + ++ HPNI+ I
Sbjct: 48 GEGGFARCF-RVKDNYGNIYAAKVIAKRSLQNDKTKL--KLFGEIKVHQSMSHPNIVGFI 104
Query: 490 EIVYENNRIFQVMEYCDY-DLFAIVMSNKMSYE-EICCCFKQILTGVEYLHSIGLAHRDM 547
+ ++ I+ ++E C++ L ++ K E E+ QIL ++Y+H + HRD+
Sbjct: 105 DCFEDSTNIYLILELCEHKSLMELLRKRKQLTEPEVRYLMMQILGALKYMHKKRVIHRDL 164
Query: 548 KLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFTKYDPR-P 606
KL N +++ VK+ DFG A + + + I G+ Y+APE+ +K
Sbjct: 165 KLGNIMLDESNNVKIGDFGLAALLMDDEERKMT----ICGTPNYIAPEILFNSKEGHSFE 220
Query: 607 VDIWSVAILFACMVLKKFPWK-------IPKLKDNSFKF----FCSGRDCDSLSALVTKT 655
VD+WS ++ +++ K P++ K+K NS+ F S D +S+L+T
Sbjct: 221 VDLWSAGVVMYALLIGKPPFQDKEVKTIYRKIKANSYSFPSNVDISAEAKDLISSLLTHD 280
Query: 656 PK-PPSYDNAVQSDEPAESTSKSNNPSDPNNTNIGPQRLLHSLP 698
P PS D+ V + S P + +LHS+P
Sbjct: 281 PSIRPSIDDIVDHEFFHTGYMASTLPDE----------ILHSMP 314
>7303211 [T] KOG4717 Serine/threonine protein kinase
Length = 860
Score = 88.6 bits (218), Expect = 3e-17
Identities = 86/324 (26%), Positives = 144/324 (43%), Gaps = 47/324 (14%)
Query: 427 ENLGAGAGGSVRLMKRISDNQVFAVKEF-RPKFEHESKRDYVKKITSEYCIGTTLRHPNI 485
E LG+G V+L + + AVK + K + SK +++ C+ ++HPN+
Sbjct: 24 ETLGSGHFAVVKLARHVFTGAKVAVKVVDKTKLDDVSKAHLFQEVR---CM-KLVQHPNV 79
Query: 486 ISTIEIVYENNRIFQVMEYCDY-DLFAIVMSNKMSYEEICC--CFKQILTGVEYLHSIGL 542
+ E++ +++ V+E D DL+ +M + E F+QIL + Y H + +
Sbjct: 80 VRLYEVIDTQTKLYLVLELGDGGDLYDYIMKHDSGLSEELARKYFRQILRAITYCHQLHV 139
Query: 543 AHRDMKLDNCVINNQ-GIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFTK 601
HRD+K +N V + G+VKL DFG + F P K GS Y APE+ +
Sbjct: 140 VHRDLKPENVVFFEKLGLVKLTDFGFSNKF-LPGQKL----ETFCGSLAYSAPEILLGDS 194
Query: 602 YDPRPVDIWSVAILFACMVLKKFPWKIPKLKDNSFKFFCSGRDC-------------DSL 648
YD VDIWS+ ++ +V + P++ K N + DC D +
Sbjct: 195 YDAPAVDIWSLGVILYMLVCGQAPFE----KANDSETLTMIMDCKYTVPSHVSTDCRDLI 250
Query: 649 SALVTKTPKPPSYDNAVQS-------DEPAESTSKSNNPSDPNNTNIGPQRLLHSLPEET 701
++++ + PK + + S DEP +TS S + P L EE
Sbjct: 251 ASMLVRDPKKRATVEEIASSAWLKPIDEPDSTTSTSE--------HFLPLVSREQLGEED 302
Query: 702 H-HIIGRMVDLAPACRANIEEVLN 724
H II +M++ A + I + L+
Sbjct: 303 HAFIIQKMINGNIASKEEILQALD 326
>7302570 [R] KOG0586 Serine/threonine protein kinase
Length = 702
Score = 88.6 bits (218), Expect = 3e-17
Identities = 62/207 (29%), Positives = 100/207 (47%), Gaps = 10/207 (4%)
Query: 422 YLKTGENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLR 481
Y + + +G G V+L I A+K +E +Y+ K E I +LR
Sbjct: 40 YYELEKTIGKGNFAVVKLATNIVTKTKVAIKIIDKTCLNE---EYLNKTFREIAILKSLR 96
Query: 482 HPNIISTIEIVYENNRIFQVMEYC-DYDLFAIVMSN-KMSYEEICCCFKQILTGVEYLHS 539
HP+I E++ + I+ V EY + ++F +++N +M E F Q+++ V Y H
Sbjct: 97 HPHITRLYEVMESQSMIYLVTEYAPNGEIFDHLVANGRMKEPEAARVFTQLVSAVHYCHR 156
Query: 540 IGLAHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIF 599
G+ HRD+K +N +++ +KL DFG + Y TL GS PY APEV
Sbjct: 157 RGVVHRDLKAENVLLDKDMNIKLADFGFSN--HYEEGATL---KTWCGSPPYAAPEVFQG 211
Query: 600 TKYDPRPVDIWSVAILFACMVLKKFPW 626
+YD DIWS+ ++ +V P+
Sbjct: 212 LEYDGPKSDIWSLGVVLYALVCGALPF 238
>7298323 [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 514
Score = 88.6 bits (218), Expect = 3e-17
Identities = 62/214 (28%), Positives = 101/214 (46%), Gaps = 11/214 (5%)
Query: 427 ENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLRHPNII 486
+ LG GA G V+L+ + A+K K +H + V+K E CI L+ +I+
Sbjct: 26 QTLGEGAYGEVKLLINRQTGEAVAMKMVDLK-KHPDAANSVRK---EVCIQKMLQDKHIL 81
Query: 487 STIEIVYENNRIFQVMEYCD----YDLFAIVMSNKMSYEEICCCFKQILTGVEYLHSIGL 542
+ + + +EY +D M E F Q+L+G+ YLH G+
Sbjct: 82 RFFGKRSQGSVEYIFLEYAAGGELFDRIGEEPDVGMPQHEAQRYFTQLLSGLNYLHQRGI 141
Query: 543 AHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFTKY 602
AHRD+K +N +++ VK+ DFG A +F + L++ G+ PY+APEV + Y
Sbjct: 142 AHRDLKPENLLLDEHDNVKISDFGMATMFRCKGKERLLDKR--CGTLPYVAPEV-LQKAY 198
Query: 603 DPRPVDIWSVAILFACMVLKKFPWKIPKLKDNSF 636
+P D+WS ++ M+ + PW P F
Sbjct: 199 HAQPADLWSCGVILVTMLAGELPWDQPSTNCTEF 232
>Hs7662170 [R] KOG0611 Predicted serine/threonine protein kinase
Length = 661
Score = 88.2 bits (217), Expect = 4e-17
Identities = 64/204 (31%), Positives = 101/204 (49%), Gaps = 13/204 (6%)
Query: 427 ENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLRHPNII 486
E LG G G V+ +V A+K R K + + ++D V I E I ++L HP+II
Sbjct: 59 ETLGKGTYGKVKRATERFSGRVVAIKSIR-KDKIKDEQDMVH-IRREIEIMSSLNHPHII 116
Query: 487 STIEIVYENNRIFQVMEYCD----YDLFAIVMSNKMSYEEICCCFKQILTGVEYLHSIGL 542
S E+ ++I +MEY YD I ++S E F+QI++ V Y H G+
Sbjct: 117 SIYEVFENKDKIVIIMEYASKGELYDY--ISERRRLSERETRHFFRQIVSAVHYCHKNGV 174
Query: 543 AHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFTKY 602
HRD+KL+N ++++ +K+ DFG + + Y K L GS Y +PE+ Y
Sbjct: 175 VHRDLKLENILLDDNCNIKIADFGLSNL--YQKDKFL---QTFCGSPLYASPEIVNGRPY 229
Query: 603 DPRPVDIWSVAILFACMVLKKFPW 626
VD W++ +L +V P+
Sbjct: 230 RGPEVDSWALGVLLYTLVYGTMPF 253
>CE21213 [UT] KOG0662 Cyclin-dependent kinase CDK5
Length = 292
Score = 88.2 bits (217), Expect = 4e-17
Identities = 66/239 (27%), Positives = 104/239 (42%), Gaps = 22/239 (9%)
Query: 427 ENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLRHPNII 486
E +G G G+V + + ++ A+K R + E + E CI L+H N++
Sbjct: 8 EKIGEGTYGTVFKARNKNSGEIVALKRVRLDDDDEGVPSSALR---EICILRELKHRNVV 64
Query: 487 STIEIVYENNRIFQVMEYCDYDL--FAIVMSNKMSYEEICCCFKQILTGVEYLHSIGLAH 544
++V+ N++ V EYCD DL F ++ M + Q+L G+ + H+ + H
Sbjct: 65 RLYDVVHSENKLTLVFEYCDQDLKKFFDSLNGYMDAQTARSLMLQLLRGLSFCHAHHVLH 124
Query: 545 RDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFTKYDP 604
RD+K N +IN G +KL DFG A F P + S V + Y P+V K
Sbjct: 125 RDLKPQNLLINTNGTLKLADFGLARAFGVP----VRCFSAEVVTLWYRPPDVLFGAKLYN 180
Query: 605 RPVDIWSVAILFACMVLKKFPWKIPKLKDNSFKFFCSGRDCDSLSALVTKTPKPPSYDN 663
+D+WS +FA + N+ + G D D + K PS DN
Sbjct: 181 TSIDMWSAGCIFAEI-------------SNAGRPLFPGADVDDQLKRIFKQLGSPSEDN 226
>At5g58380 [T] KOG0583 Serine/threonine protein kinase
Length = 464
Score = 88.2 bits (217), Expect = 4e-17
Identities = 58/202 (28%), Positives = 97/202 (47%), Gaps = 5/202 (2%)
Query: 426 GENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLRHPNI 485
G LG G V + I NQ A+K E K +++I E + RHPN+
Sbjct: 15 GRLLGQGTFAKVYYGRSILTNQSVAIKMIDK--EKVMKVGLIEQIKREISVMRIARHPNV 72
Query: 486 ISTIEIVYENNRIFQVMEYCDY-DLFAIVMSNKMSYEEICCCFKQILTGVEYLHSIGLAH 544
+ E++ RI+ VMEYC +LF V K+ + F Q++ V++ HS + H
Sbjct: 73 VELYEVMATKTRIYFVMEYCKGGELFNKVAKGKLRDDVAWKYFYQLINAVDFCHSREVYH 132
Query: 545 RDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFTKYDP 604
RD+K +N ++++ +K+ DFG + + L+ ++ G+ Y+APEV YD
Sbjct: 133 RDIKPENLLLDDNENLKVSDFGLSALADCKRQDGLLHTT--CGTPAYVAPEVINRKGYDG 190
Query: 605 RPVDIWSVAILFACMVLKKFPW 626
DIWS ++ ++ P+
Sbjct: 191 TKADIWSCGVVLFVLLAGYLPF 212
>At1g74330 [D] KOG0600 Cdc2-related protein kinase
Length = 445
Score = 88.2 bits (217), Expect = 4e-17
Identities = 68/203 (33%), Positives = 105/203 (51%), Gaps = 12/203 (5%)
Query: 427 ENLGAGAGGSVRLMKRISDNQVFAVKEFR-PKFEHESKRDYVKKITSEYCIGTTLRHPNI 485
E +G G +V ++ A+K+ R FE ES VK + E I L HPNI
Sbjct: 125 EKIGQGTYSNVFRAVETETGRIVALKKVRFDNFEPES----VKFMAREILILRRLNHPNI 180
Query: 486 ISTIEIVYE--NNRIFQVMEYCDYDLFAIVMSN--KMSYEEICCCFKQILTGVEYLHSIG 541
I ++ + I V EY ++DL ++ S K + +I C KQ+L+G+++ HS G
Sbjct: 181 IKLEGLITSKLSCNIQLVFEYMEHDLTGLLSSPDIKFTTPQIKCYMKQLLSGLDHCHSRG 240
Query: 542 LAHRDMKLDNCVINNQGIVKLIDFGAAEVF-SYPHSKTLIESSGIVGSDPYLAPEVCIFT 600
+ HRD+K N +++N+GI+K+ DFG A S H K + S V + Y PE+ +
Sbjct: 241 VMHRDIKGSNLLLSNEGILKVADFGLANFSNSSGHKKKPLTSR--VVTLWYRPPELLLGA 298
Query: 601 KYDPRPVDIWSVAILFACMVLKK 623
VD+WSV +FA ++L K
Sbjct: 299 TDYGASVDLWSVGCVFAELLLGK 321
>7299438 [R] KOG0586 Serine/threonine protein kinase
Length = 705
Score = 88.2 bits (217), Expect = 4e-17
Identities = 58/209 (27%), Positives = 102/209 (48%), Gaps = 10/209 (4%)
Query: 427 ENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLRHPNII 486
+ LG G V+L + + A+K + S R +K+ E I L HPNI+
Sbjct: 102 KTLGKGNFAKVKLAIHVPTGREVAIKVIDKTQLNTSAR---QKLYREVKIMKLLNHPNIV 158
Query: 487 STIEIVYENNRIFQVMEYCDY-DLFA-IVMSNKMSYEEICCCFKQILTGVEYLHSIGLAH 544
+++ ++ VMEY +LF +V + +M + F+Q+++ ++Y HS + H
Sbjct: 159 RLFQVIESERTLYLVMEYASRGELFDHLVKNGRMRERDARVIFRQLVSAIQYCHSKFVVH 218
Query: 545 RDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFTKYDP 604
RD+K +N +++ +K+ DFG F P++ + GS PY APE+ + KY
Sbjct: 219 RDLKAENLLLDQHMNIKIADFGFGNTFD-PNA----QLETFCGSPPYAAPELFMGRKYAG 273
Query: 605 RPVDIWSVAILFACMVLKKFPWKIPKLKD 633
VD WS+ ++ +V P+ LK+
Sbjct: 274 PEVDAWSLGVVLYTLVSGSLPFDGGTLKE 302
>YDR507c [D] KOG0588 Serine/threonine protein kinase
Length = 1142
Score = 87.8 bits (216), Expect = 6e-17
Identities = 60/217 (27%), Positives = 104/217 (47%), Gaps = 19/217 (8%)
Query: 424 KTGENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITS----------- 472
K GE LG G+ G V+L + S Q AVK + + S
Sbjct: 20 KLGETLGLGSTGKVQLARNGSTGQEAAVKVISKAVFNTGNVSGTSIVGSTTPDALPYGIE 79
Query: 473 -EYCIGTTLRHPNIISTIEIVYENNRIFQVMEYCDY-DLFAIVMSN-KMSYEEICCCFKQ 529
E I L HPN++ ++ N ++ V+EY + +LF +++ + E F+Q
Sbjct: 80 REIIIMKLLNHPNVLRLYDVWETNTDLYLVLEYAEKGELFNLLVERGPLPEHEAIRFFRQ 139
Query: 530 ILTGVEYLHSIGLAHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSD 589
I+ GV Y H++G+ HRD+K +N +++++ +K+ DFG A + + L+E+S GS
Sbjct: 140 IIIGVSYCHALGIVHRDLKPENLLLDHKYNIKIADFGMAALET---EGKLLETS--CGSP 194
Query: 590 PYLAPEVCIFTKYDPRPVDIWSVAILFACMVLKKFPW 626
Y APE+ Y D+WS ++ ++ + P+
Sbjct: 195 HYAAPEIVSGIPYQGFASDVWSCGVILFALLTGRLPF 231
>Hs4502731 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 360
Score = 87.8 bits (216), Expect = 6e-17
Identities = 59/194 (30%), Positives = 100/194 (51%), Gaps = 13/194 (6%)
Query: 429 LGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHES-KRDYVKKITSEYCIGTTLRHPNIIS 487
+G G G V + +++ A+K+ R E + +++IT + LRHPNI+
Sbjct: 45 IGEGTYGIVYRARDTQTDEIVALKKVRMDKEKDGIPISSLREIT----LLLRLRHPNIVE 100
Query: 488 TIEIVYENN--RIFQVMEYCDYDLFAIV--MSNKMSYEEICCCFKQILTGVEYLHSIGLA 543
E+V N+ IF VM YC+ DL +++ M S ++ C Q+L G++YLH +
Sbjct: 101 LKEVVVGNHLESIFLVMGYCEQDLASLLENMPTPFSEAQVKCIVLQVLRGLQYLHRNFII 160
Query: 544 HRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFTKYD 603
HRD+K+ N ++ ++G VK DFG A + P + + V + Y APE+ + T
Sbjct: 161 HRDLKVSNLLMTDKGCVKTADFGLARAYGVP----VKPMTPKVVTLWYRAPELLLGTTTQ 216
Query: 604 PRPVDIWSVAILFA 617
+D+W+V + A
Sbjct: 217 TTSIDMWAVGCILA 230
>Hs16950647 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 314
Score = 87.8 bits (216), Expect = 6e-17
Identities = 59/194 (30%), Positives = 100/194 (51%), Gaps = 13/194 (6%)
Query: 429 LGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHES-KRDYVKKITSEYCIGTTLRHPNIIS 487
+G G G V + +++ A+K+ R E + +++IT + LRHPNI+
Sbjct: 16 IGEGTYGIVYRARDTQTDEIVALKKVRMDKEKDGIPISSLREIT----LLLRLRHPNIVE 71
Query: 488 TIEIVYENN--RIFQVMEYCDYDLFAIV--MSNKMSYEEICCCFKQILTGVEYLHSIGLA 543
E+V N+ IF VM YC+ DL +++ M S ++ C Q+L G++YLH +
Sbjct: 72 LKEVVVGNHLESIFLVMGYCEQDLASLLENMPTPFSEAQVKCIVLQVLRGLQYLHRNFII 131
Query: 544 HRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFTKYD 603
HRD+K+ N ++ ++G VK DFG A + P + + V + Y APE+ + T
Sbjct: 132 HRDLKVSNLLMTDKGCVKTADFGLARAYGVP----VKPMTPKVVTLWYRAPELLLGTTTQ 187
Query: 604 PRPVDIWSVAILFA 617
+D+W+V + A
Sbjct: 188 TTSIDMWAVGCILA 201
>At2g34180 [T] KOG0583 Serine/threonine protein kinase
Length = 502
Score = 87.8 bits (216), Expect = 6e-17
Identities = 57/203 (28%), Positives = 103/203 (50%), Gaps = 7/203 (3%)
Query: 426 GENLGAGAGGSVRLMKRISDNQVFAVKEF-RPKFEHESKRDYVKKITSEYCIGTTLRHPN 484
G+ LG G+ V L + I + A+K + K ++K+ E I +RHP
Sbjct: 60 GKLLGHGSFAKVYLARNIHSGEDVAIKVIDKEKIVKSGLAGHIKR---EISILRRVRHPY 116
Query: 485 IISTIEIVYENNRIFQVMEYC-DYDLFAIVMSNKMSYEEICCCFKQILTGVEYLHSIGLA 543
I+ +E++ +I+ VMEY +L+ V ++ F+Q+++ V + HS G+
Sbjct: 117 IVHLLEVMATKTKIYIVMEYVRGGELYNTVARGRLREGTARRYFQQLISSVAFCHSRGVY 176
Query: 544 HRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFTKYD 603
HRD+KL+N +++++G VK+ DFG + V + + ++ G+ YLAPEV Y+
Sbjct: 177 HRDLKLENLLLDDKGNVKVSDFGLSVVSEQLKQEGICQT--FCGTPAYLAPEVLTRKGYE 234
Query: 604 PRPVDIWSVAILFACMVLKKFPW 626
DIWS ++ ++ P+
Sbjct: 235 GAKADIWSCGVILFVLMAGYLPF 257
>At1g48260 [T] KOG0583 Serine/threonine protein kinase
Length = 432
Score = 87.8 bits (216), Expect = 6e-17
Identities = 59/203 (29%), Positives = 98/203 (48%), Gaps = 6/203 (2%)
Query: 426 GENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLRHPNI 485
G LG G V+ + FA+K + +I E L+HPNI
Sbjct: 14 GRTLGEGNSAKVKFAIDTLTGESFAIKIIEKSCITRLNVSF--QIKREIRTLKVLKHPNI 71
Query: 486 ISTIEIVYENNRIFQVME-YCDYDLF-AIVMSNKMSYEEICCCFKQILTGVEYLHSIGLA 543
+ E++ +I+ V+E DLF IV K+S + F+Q++ GV Y H+ G+
Sbjct: 72 VRLHEVLASKTKIYMVLECVTGGDLFDRIVSKGKLSETQGRKMFQQLIDGVSYCHNKGVF 131
Query: 544 HRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFTKYD 603
HRD+KL+N +++ +G +K+ DFG + + + L+ ++ GS Y+APEV YD
Sbjct: 132 HRDLKLENVLLDAKGHIKITDFGLSALSQHYREDGLLHTT--CGSPNYVAPEVLANEGYD 189
Query: 604 PRPVDIWSVAILFACMVLKKFPW 626
DIWS ++ ++ P+
Sbjct: 190 GAASDIWSCGVILYVILTGCLPF 212
>7290565 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 353
Score = 87.8 bits (216), Expect = 6e-17
Identities = 83/323 (25%), Positives = 149/323 (45%), Gaps = 33/323 (10%)
Query: 419 SKRYLKTGENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKIT-SEYCIG 477
++RY K LG G +V + NQ+ AVK+ + K E RD + + E I
Sbjct: 9 TERYAKLSF-LGEGQFATVYKARDTVTNQIVAVKKIK-KGSREDARDGINRTALREIKIL 66
Query: 478 TTLRHPNIISTIEIVYENNRIFQVMEYCDYDLFAIVMSNKMSYEEICCCFKQILT--GVE 535
L+H NII +++ + + + V ++ D DL I+ NK+ + I+T G+E
Sbjct: 67 QELQHENIIGLVDVFGQLSNVSLVFDFMDTDLEVIIKDNKIILTQANIKAYAIMTLKGLE 126
Query: 536 YLHSIGLAHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPE 595
YLH + HRD+K +N ++N+ GI+K+ DFG A+ F P+ I + +V + Y +PE
Sbjct: 127 YLHLNWILHRDLKPNNLLVNSDGILKIGDFGLAKSFGSPNR---IYTHHVV-TRWYRSPE 182
Query: 596 VCIFTKYDPRPVDIWSVAILFACMVLKKFPWKIPKLKDNSFKFFCSGRDCDSLSALVTK- 654
+ + VD+W+V + A ++L ++P + +S D D L+ + +
Sbjct: 183 LLFGARQYGTGVDMWAVGCILAELML-----RVPFMPGDS--------DLDQLTRIFSTL 229
Query: 655 -TPKPPSYDNAVQSDEPAESTSKSNNPSDPNNTNIGPQRLLHSLPEETHHIIGRMVDLAP 713
TP + + + + + + P D T G + H++ R+ + P
Sbjct: 230 GTPTEAEWPHLSKLHDYLQFRNFPGTPLDNIFTAAG---------NDLIHLMQRLFAMNP 280
Query: 714 ACRANIEEVLNDPWIQSIDMCTV 736
R + E L+ P+ + TV
Sbjct: 281 LRRVSCREALSMPYFANKPAPTV 303
>Hs7382496 [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 545
Score = 87.4 bits (215), Expect = 7e-17
Identities = 64/219 (29%), Positives = 109/219 (49%), Gaps = 16/219 (7%)
Query: 420 KRYLKTGENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTT 479
K+Y + E +G GA G+V ++ Q A+K+ + + K++ I +E +
Sbjct: 268 KKYTRF-EKIGQGASGTVYTAMDVATGQEVAIKQMN--LQQQPKKEL---IINEILVMRE 321
Query: 480 LRHPNIISTIEIVYENNRIFQVMEY-CDYDLFAIVMSNKMSYEEICCCFKQILTGVEYLH 538
++PNI++ ++ + ++ VMEY L +V M +I ++ L +E+LH
Sbjct: 322 NKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALEFLH 381
Query: 539 SIGLAHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCI 598
S + HRD+K DN ++ G VKL DFG + SK S +VG+ ++APEV
Sbjct: 382 SNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSK----RSTMVGTPYWMAPEVVT 437
Query: 599 FTKYDPRPVDIWSVAILFACMVLKKFPWKIPKLKDNSFK 637
Y P+ VDIWS+ I M ++ + P L +N +
Sbjct: 438 RKAYGPK-VDIWSLGI----MAIEMIEGEPPYLNENPLR 471
>Hs4505599 [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 525
Score = 87.4 bits (215), Expect = 7e-17
Identities = 63/209 (30%), Positives = 108/209 (51%), Gaps = 13/209 (6%)
Query: 420 KRYLKTGENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTT 479
K+Y + E +G GA G+V ++ Q A+K+ + + K++ I +E +
Sbjct: 247 KKYTRY-EKIGQGASGTVFTATDVALGQEVAIKQIN--LQKQPKKEL---IINEILVMKE 300
Query: 480 LRHPNIISTIEIVYENNRIFQVMEYCDYDLFAIVMSNKMSYEE--ICCCFKQILTGVEYL 537
L++PNI++ ++ + +F VMEY V++ +E I ++ L +E+L
Sbjct: 301 LKNPNIVNFLDSYLVGDELFVVMEYLAGGSLTDVVTETACMDEAQIAAVCRECLQALEFL 360
Query: 538 HSIGLAHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVC 597
H+ + HRD+K DN ++ +G VKL DFG + SK S +VG+ ++APEV
Sbjct: 361 HANQVIHRDIKSDNVLLGMEGSVKLTDFGFCAQITPEQSK----RSTMVGTPYWMAPEVV 416
Query: 598 IFTKYDPRPVDIWSVAILFACMVLKKFPW 626
Y P+ VDIWS+ I+ MV + P+
Sbjct: 417 TRKAYGPK-VDIWSLGIMAIEMVEGEPPY 444
>Hs16357494 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 775
Score = 87.4 bits (215), Expect = 7e-17
Identities = 63/198 (31%), Positives = 106/198 (52%), Gaps = 15/198 (7%)
Query: 432 GAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLR--HPNIISTI 489
G G V K +++ A+K + + E+E ITS I T L+ HPNI++
Sbjct: 427 GTYGVVYRAKDKKTDEIVALKRLKMEKENEGF-----PITSLREINTILKAQHPNIVTVR 481
Query: 490 EIVYENN--RIFQVMEYCDYDLFAIVMSNKMSY--EEICCCFKQILTGVEYLHSIGLAHR 545
EIV +N +I+ VM Y ++DL +++ + K + E+ Q+L GV++LH + HR
Sbjct: 482 EIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHR 541
Query: 546 DMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFTKYDPR 605
D+K N ++++ GI+K+ DFG A + P L + +V + Y APE+ + K
Sbjct: 542 DLKTSNLLLSHAGILKVGDFGLAREYGSP----LKAYTPVVVTQWYRAPELLLGAKEYST 597
Query: 606 PVDIWSVAILFACMVLKK 623
VD+WSV +F ++ +K
Sbjct: 598 AVDMWSVGCIFGELLTQK 615
>Hs16357492 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 777
Score = 87.4 bits (215), Expect = 7e-17
Identities = 63/198 (31%), Positives = 106/198 (52%), Gaps = 15/198 (7%)
Query: 432 GAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLR--HPNIISTI 489
G G V K +++ A+K + + E+E ITS I T L+ HPNI++
Sbjct: 429 GTYGVVYRAKDKKTDEIVALKRLKMEKENEGF-----PITSLREINTILKAQHPNIVTVR 483
Query: 490 EIVYENN--RIFQVMEYCDYDLFAIVMSNKMSY--EEICCCFKQILTGVEYLHSIGLAHR 545
EIV +N +I+ VM Y ++DL +++ + K + E+ Q+L GV++LH + HR
Sbjct: 484 EIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHR 543
Query: 546 DMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFTKYDPR 605
D+K N ++++ GI+K+ DFG A + P L + +V + Y APE+ + K
Sbjct: 544 DLKTSNLLLSHAGILKVGDFGLAREYGSP----LKAYTPVVVTQWYRAPELLLGAKEYST 599
Query: 606 PVDIWSVAILFACMVLKK 623
VD+WSV +F ++ +K
Sbjct: 600 AVDMWSVGCIFGELLTQK 617
>CE01761 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 719
Score = 87.4 bits (215), Expect = 7e-17
Identities = 57/199 (28%), Positives = 107/199 (53%), Gaps = 13/199 (6%)
Query: 432 GAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLRHPNIISTIEI 491
G G V K +++ A+K R K E E + + + + HPNI++ EI
Sbjct: 365 GTFGVVYRGKDKRTDEIVALK--RLKMEKEKEGFPITALREINMLLKAGNHPNIVNVKEI 422
Query: 492 VYENN--RIFQVMEYCDYDLFAIV-----MSNKMSYEEICCCFKQILTGVEYLHSIGLAH 544
+ +N +I+ ME+ ++D+ +++ + + S E +Q+L+G+E++H + + H
Sbjct: 423 LLGSNMDKIYMAMEFVEHDMKSLLDTMSRRNKRFSIGEQKTLLQQLLSGIEHMHKLWILH 482
Query: 545 RDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFTKYDP 604
RD+K N +++++GI+K+ DFG A + P L + + IV + Y +PE+ + T+
Sbjct: 483 RDLKTSNLLMSHKGILKIADFGLAREYGDP----LKKFTSIVVTLWYRSPELLLGTRLYS 538
Query: 605 RPVDIWSVAILFACMVLKK 623
PVD+WSV + A +L K
Sbjct: 539 TPVDMWSVGCIMAEFILLK 557
>At4g13020 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 443
Score = 87.4 bits (215), Expect = 7e-17
Identities = 86/324 (26%), Positives = 140/324 (42%), Gaps = 40/324 (12%)
Query: 427 ENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLRHPNII 486
E LG G GSV + +V AVK+ + KF + + ++++ + L HP+II
Sbjct: 16 EELGDGTCGSVYKAVNLETYEVVAVKKMKRKFYYWEECVNLREVKAL----RKLNHPHII 71
Query: 487 STIEIVYENNRIFQVMEYCDYDLFAIVMSNKMSYE--EICCCFKQILTGVEYLHSIGLAH 544
EIV E+N +F + E D++L+ I+ + + EI Q+L G+ ++H G H
Sbjct: 72 KLKEIVREHNELFFIFECMDHNLYHIMKERERPFSEGEIRSFMSQMLQGLAHMHKNGYFH 131
Query: 545 RDMKLDNCVINNQGIVKLIDFG-AAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFTKYD 603
RD+K +N ++ N I+K+ DFG A EV S P + V + Y APEV + +
Sbjct: 132 RDLKPENLLVTN-NILKIADFGLAREVASMP------PYTEYVSTRWYRAPEVLLQSSLY 184
Query: 604 PRPVDIWSVAILFACMVLKKFPWKIPKLKDNSFKFFCSGRDCDSLSALVTKTPKPPSYDN 663
VD+W+V + A + F + D L + KP D
Sbjct: 185 TPAVDMWAVGAILAELYALT-------------PLFPGESEIDQLYKICCVLGKP---DW 228
Query: 664 AVQSDEPAESTSKSNNPSDPNNTNIGPQRLLHSLPEETHHIIGRMVDLAPACRANIEEVL 723
+ + S S + ++ T I LL + E +I R+ P R +E L
Sbjct: 229 TTFPEAKSISRIMSISHTEFPQTRIAD--LLPNAAPEAIDLINRLCSWDPLKRPTADEAL 286
Query: 724 NDPWIQSIDMCTVEVDNQGNYVVH 747
N P+ + Q +Y +H
Sbjct: 287 NHPFF--------SMATQASYPIH 302
>At3g17510 [T] KOG0583 Serine/threonine protein kinase
Length = 446
Score = 87.4 bits (215), Expect = 7e-17
Identities = 60/203 (29%), Positives = 102/203 (49%), Gaps = 6/203 (2%)
Query: 426 GENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLRHPNI 485
G LG G G V+ K FAVK + ++ +I E L+HP+I
Sbjct: 23 GRTLGEGNFGKVKFAKDTVSGHSFAVKIIDKS--RIADLNFSLQIKREIRTLKMLKHPHI 80
Query: 486 ISTIEIVYENNRIFQVMEYCDY-DLFAIVMSN-KMSYEEICCCFKQILTGVEYLHSIGLA 543
+ E++ +I VME +LF ++SN K++ + F+Q++ G+ Y HS G+
Sbjct: 81 VRLHEVLASKTKINMVMELVTGGELFDRIVSNGKLTETDGRKMFQQLIDGISYCHSKGVF 140
Query: 544 HRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFTKYD 603
HRD+KL+N +++ +G +K+ DFG + + + L+ ++ GS Y+APEV YD
Sbjct: 141 HRDLKLENVLLDAKGHIKITDFGLSALPQHFRDDGLLHTT--CGSPNYVAPEVLANRGYD 198
Query: 604 PRPVDIWSVAILFACMVLKKFPW 626
DIWS ++ ++ P+
Sbjct: 199 GAASDIWSCGVILYVILTGCLPF 221
>7298926 [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 704
Score = 87.4 bits (215), Expect = 7e-17
Identities = 63/220 (28%), Positives = 109/220 (48%), Gaps = 16/220 (7%)
Query: 419 SKRYLKTGENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGT 478
+++Y K E +G GA G+V S A+K+ + K++ I +E +
Sbjct: 427 NRKYTKM-EKIGQGASGTVYTAIESSTGMEVAIKQMN--LSQQPKKEL---IINEILVMR 480
Query: 479 TLRHPNIISTIEIVYENNRIFQVMEYCDY-DLFAIVMSNKMSYEEICCCFKQILTGVEYL 537
+HPN+++ ++ + ++ VMEY L +V M +I +++L +E+L
Sbjct: 481 ENKHPNVVNYLDSYLVSEELWVVMEYLPGGSLTDVVTETCMDEGQIAAVCREVLQALEFL 540
Query: 538 HSIGLAHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVC 597
H+ + HRD+K DN ++ G VKL DFG S SK + +VG+ ++APEV
Sbjct: 541 HANQVIHRDIKSDNILLGLDGSVKLTDFGFCAQISPEQSK----RTTMVGTPYWMAPEVV 596
Query: 598 IFTKYDPRPVDIWSVAILFACMVLKKFPWKIPKLKDNSFK 637
+Y P+ VD+WS+ I M ++ + P L +N K
Sbjct: 597 TRKQYGPK-VDLWSLGI----MAIEMVEGEPPYLNENPLK 631
>CE02602_1 [T] KOG0660 Mitogen-activated protein kinase
Length = 342
Score = 87.4 bits (215), Expect = 7e-17
Identities = 89/324 (27%), Positives = 151/324 (46%), Gaps = 51/324 (15%)
Query: 427 ENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLRHPNII 486
ENLGAGA G V N+ A+K+ F+++S K E I L H NII
Sbjct: 48 ENLGAGAFGVVCRAIDSKLNKQVAIKKITRVFKNQST---AKCALREIRITRELSHENII 104
Query: 487 STIEIVYENNR----IFQVMEYCDYDLFAIVMSNK-MSYEEICCCFKQILTGVEYLHSIG 541
++ +++ + I+ VM+ + DL +++ SN+ ++ + F QIL G++YLHS G
Sbjct: 105 NSTDVLMRESGSGQDIYIVMDLMETDLLSVLKSNQTLNEKHFQYFFYQILKGLKYLHSAG 164
Query: 542 LAHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIES----------SGIVGSDPY 591
+ HRD+K N ++N +K+ DFG + S P +KT + S V + Y
Sbjct: 165 IIHRDLKPANLLLNEDCSLKIADFGMSR--SGPSTKTTPNTSPNAHISGDLSQYVSTLWY 222
Query: 592 LAPEVCI-FTKYDPRPVDIWSVAILFACMVLKKFPWKIPKLKDNSFKFFCSGRDCDSLSA 650
APE+ + +YD + VDIWS + A M+L + +G D S
Sbjct: 223 RAPEILLSMGEYDTQ-VDIWSAGCILAEMLL--------------LRPIFTGTDSYSQIQ 267
Query: 651 LVTKTPKPPSYDNAVQSDEPAESTSKSNNPSDPNNTNIGPQ------RLLHSLPEETHHI 704
L+ + P DE KS + D ++ GP+ + + E +I
Sbjct: 268 LLIEYLGTP--------DEQVIRRIKSPSIRD-YISSFGPKTPLPFTAMFPNASIEARNI 318
Query: 705 IGRMVDLAPACRANIEEVLNDPWI 728
+ +M+ ++P R + E++L +P++
Sbjct: 319 VSKMLQISPWKRFSAEQLLEEPFV 342
>YGL179c [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kinase beta
and related serine/threonine protein kinases
Length = 560
Score = 87.0 bits (214), Expect = 1e-16
Identities = 69/240 (28%), Positives = 112/240 (45%), Gaps = 33/240 (13%)
Query: 417 PFSKRYLKTG----ENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITS 472
P +KR + LG G G V+L + + + A+K +FE S K+ +
Sbjct: 40 PLTKRQILNNFEILATLGNGQYGKVKLARDLGTGALVAIKILN-RFEKRSGYSLQLKVEN 98
Query: 473 -----EYCIGTTLRHPNIISTIEIVY--ENNRIFQVMEYCDYDLFAIVMSNKMSYEEI-- 523
E + H N++ EI+ E+ +++ V+EYC NKM + +
Sbjct: 99 PRVNQEIEVMKRCHHENVVELYEILNDPESTKVYLVLEYCSRGPVKWCPENKMEIKAVGP 158
Query: 524 -CCCFKQ-------ILTGVEYLHSIGLAHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPH 575
F+Q +++G+EYLHS G+ HRD+K N +I++ G VK+ DFG A S
Sbjct: 159 SILTFQQSRKVVLDVVSGLEYLHSQGITHRDIKPSNLLISSNGTVKISDFGVA--MSTAT 216
Query: 576 SKTLIES-------SGIVGSDPYLAPEVCIFTK-YD-PRPVDIWSVAILFACMVLKKFPW 626
T I+S S +G+ + APE+C K Y +DIWS+ + C++ K P+
Sbjct: 217 GSTNIQSSHEQLLKSRALGTPAFFAPELCSTEKEYSCSSAIDIWSLGVTIYCLLFGKLPF 276
>Hs6031180 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and related
serine/threonine protein kinases
Length = 1558
Score = 87.0 bits (214), Expect = 1e-16
Identities = 58/203 (28%), Positives = 90/203 (43%), Gaps = 5/203 (2%)
Query: 426 GENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLRHPNI 485
G +G G G V + ++ A+KE R F+ + +K+ E I ++HPN+
Sbjct: 1296 GNKIGEGQYGKVYTCISVDTGELMAMKEIR--FQPNDHKT-IKETADELKIFEGIKHPNL 1352
Query: 486 ISTIEIVYENNRIFQVMEYCDYDLFAIVMSNKMSYEEICCCFKQILTGVEYLHSIGLAHR 545
+ + ++ MEYCD V + I KQI + LH G+ HR
Sbjct: 1353 VRYFGVELHREEMYIFMEYCDEGTLEEVSRLGLQEHVIRLYSKQITIAINVLHEHGIVHR 1412
Query: 546 DMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFTKYD-- 603
D+K N + + G++KL DFG + E + +G+ Y+APEV K +
Sbjct: 1413 DIKGANIFLTSSGLIKLGDFGCSVKLKNNAQTMPGEVNSTLGTAAYMAPEVITRAKGEGH 1472
Query: 604 PRPVDIWSVAILFACMVLKKFPW 626
R DIWS+ + MV K PW
Sbjct: 1473 GRAADIWSLGCVVIEMVTGKRPW 1495
>Hs5803088 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and related
serine/threonine protein kinases
Length = 1607
Score = 87.0 bits (214), Expect = 1e-16
Identities = 58/203 (28%), Positives = 90/203 (43%), Gaps = 5/203 (2%)
Query: 426 GENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLRHPNI 485
G +G G G V + ++ A+KE R F+ + +K+ E I ++HPN+
Sbjct: 1345 GNKIGEGQYGKVYTCISVDTGELMAMKEIR--FQPNDHKT-IKETADELKIFEGIKHPNL 1401
Query: 486 ISTIEIVYENNRIFQVMEYCDYDLFAIVMSNKMSYEEICCCFKQILTGVEYLHSIGLAHR 545
+ + ++ MEYCD V + I KQI + LH G+ HR
Sbjct: 1402 VRYFGVELHREEMYIFMEYCDEGTLEEVSRLGLQEHVIRLYSKQITIAINVLHEHGIVHR 1461
Query: 546 DMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFTKYD-- 603
D+K N + + G++KL DFG + E + +G+ Y+APEV K +
Sbjct: 1462 DIKGANIFLTSSGLIKLGDFGCSVKLKNNAQTMPGEVNSTLGTAAYMAPEVITRAKGEGH 1521
Query: 604 PRPVDIWSVAILFACMVLKKFPW 626
R DIWS+ + MV K PW
Sbjct: 1522 GRAADIWSLGCVVIEMVTGKRPW 1544
>Hs13569922 [R] KOG0611 Predicted serine/threonine protein kinase
Length = 628
Score = 87.0 bits (214), Expect = 1e-16
Identities = 61/203 (30%), Positives = 105/203 (51%), Gaps = 12/203 (5%)
Query: 427 ENLGAGAGGSVRLMKRISDNQVFAVKEFRP-KFEHESKRDYVKKITSEYCIGTTLRHPNI 485
E LG G G V+ R S ++ A+K R K + E ++++ E I ++L HP+I
Sbjct: 57 ETLGKGTYGKVK-KARESSGRLVAIKSIRKDKIKDEQDLMHIRR---EIEIMSSLNHPHI 112
Query: 486 ISTIEIVYENNRIFQVMEYCDY-DLFAIVMSNK-MSYEEICCCFKQILTGVEYLHSIGLA 543
I+ E+ +++I VMEY DL+ + + +S E F+QI++ V Y H +
Sbjct: 113 IAIHEVFENSSKIVIVMEYASRGDLYDYISERQQLSEREARHFFRQIVSAVHYCHQNRVV 172
Query: 544 HRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFTKYD 603
HRD+KL+N +++ G +K+ DFG + ++ H +++ GS Y +PE+ Y
Sbjct: 173 HRDLKLENILLDANGNIKIADFGLSNLY---HQGKFLQT--FCGSPLYASPEIVNGKPYT 227
Query: 604 PRPVDIWSVAILFACMVLKKFPW 626
VD WS+ +L +V P+
Sbjct: 228 GPEVDSWSLGVLLYILVHGTMPF 250
>At5g50860 [D] KOG0600 Cdc2-related protein kinase
Length = 580
Score = 87.0 bits (214), Expect = 1e-16
Identities = 59/202 (29%), Positives = 103/202 (50%), Gaps = 12/202 (5%)
Query: 427 ENLGAGAGGSVRLMKRISDNQVFAVKEFR-PKFEHESKRDYVKKITSEYCIGTTLRHPNI 485
E +G G +V K + ++ A+K+ R E ES VK + E + L HPN+
Sbjct: 118 EKIGQGTYSNVYKAKDLLSGKIVALKKVRFDNLEAES----VKFMAREILVLRRLNHPNV 173
Query: 486 ISTIEIVYE--NNRIFQVMEYCDYDLFAIVMSNKMSYE--EICCCFKQILTGVEYLHSIG 541
I +V + ++ V EY ++DL + + + ++ ++ C KQ+L+G+E+ HS G
Sbjct: 174 IKLQGLVTSRVSCSLYLVFEYMEHDLSGLAATQGLKFDLPQVKCFMKQLLSGLEHCHSRG 233
Query: 542 LAHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFTK 601
+ HRD+K N +I+N GI+K+ DFG A + +T+ + V + Y PE+ +
Sbjct: 234 VLHRDIKGSNLLIDNDGILKIADFGLATFYDPKQKQTM---TSRVVTLWYRPPELLLGAT 290
Query: 602 YDPRPVDIWSVAILFACMVLKK 623
VD+WS + A ++ K
Sbjct: 291 SYGTGVDLWSAGCIMAELLAGK 312
>At4g24400 [T] KOG0583 Serine/threonine protein kinase
Length = 445
Score = 87.0 bits (214), Expect = 1e-16
Identities = 64/232 (27%), Positives = 112/232 (47%), Gaps = 8/232 (3%)
Query: 426 GENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLRHPNI 485
G +G G V+ + + A+K KR V +I E I +RHP +
Sbjct: 12 GRTIGEGTFAKVKFAQNTETGESVAMKIVDRSTI--IKRKMVDQIKREISIMKLVRHPCV 69
Query: 486 ISTIEIVYENNRIFQVMEYCDY-DLF-AIVMSNKMSYEEICCCFKQILTGVEYLHSIGLA 543
+ E++ +I+ ++EY +LF IV + ++S E F Q++ GV+Y HS G+
Sbjct: 70 VRLYEVLASRTKIYIILEYITGGELFDKIVRNGRLSESEARKYFHQLIDGVDYCHSKGVY 129
Query: 544 HRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFTKYD 603
HRD+K +N ++++QG +K+ DFG + + T+++++ G+ Y+APEV Y+
Sbjct: 130 HRDLKPENLLLDSQGNLKISDFGLSAL--PEQGVTILKTT--CGTPNYVAPEVLSHKGYN 185
Query: 604 PRPVDIWSVAILFACMVLKKFPWKIPKLKDNSFKFFCSGRDCDSLSALVTKT 655
DIWS ++ ++ P+ L K + C S AL K+
Sbjct: 186 GAVADIWSCGVILYVLMAGYLPFDEMDLPTLYSKIDKAEFSCPSYFALGAKS 237
>At3g18040 [T] KOG0660 Mitogen-activated protein kinase
Length = 613
Score = 87.0 bits (214), Expect = 1e-16
Identities = 65/211 (30%), Positives = 107/211 (49%), Gaps = 15/211 (7%)
Query: 427 ENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLRHPNII 486
E +G G+ G V + A+K+ FEH S +I E + LRHP+I+
Sbjct: 130 EVIGKGSYGVVASAIDTHSGEKVAIKKINDVFEHVSD---ATRILREIKLLRLLRHPDIV 186
Query: 487 STIEIVYENNR-----IFQVMEYCDYDLFAIVMSNK-MSYEEICCCFKQILTGVEYLHSI 540
++ +R I+ V E + DL ++ +N ++ E Q+L G++++H+
Sbjct: 187 EIKHVMLPPSRREFRDIYVVFELMESDLHQVIKANDDLTPEHYQFFLYQLLRGLKFIHTA 246
Query: 541 GLAHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVC--I 598
+ HRD+K N + N+ +K+ DFG A V S+ + + I + V + Y APE+C
Sbjct: 247 NVFHRDLKPKNILANSDCKLKICDFGLARV-SFNDAPSAIFWTDYVATRWYRAPELCGSF 305
Query: 599 FTKYDPRPVDIWSVAILFACMVLKK--FPWK 627
F+KY P +DIWS+ +FA M+ K FP K
Sbjct: 306 FSKYTP-AIDIWSIGCIFAEMLTGKPLFPGK 335
>Hs7705551 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 632
Score = 86.7 bits (213), Expect = 1e-16
Identities = 58/199 (29%), Positives = 97/199 (48%), Gaps = 19/199 (9%)
Query: 425 TGENLGAGAGGSVRLMKRISDNQVFAVKEFRPKF---EHESKRDYVKKITSEYCIGTTLR 481
T LG G GSV L + I ++ A+K+ + KF E + VK + L
Sbjct: 6 TIRQLGDGTYGSVLLGRSIESGELIAIKKMKRKFYSWEECMNQREVKSLKK-------LN 58
Query: 482 HPNIISTIEIVYENNRIFQVMEYCDYDLFAIVMSNKMSYEE--ICCCFKQILTGVEYLHS 539
H N++ E++ EN+ ++ + EY +L+ ++ + E I QIL G+ ++H
Sbjct: 59 HANVVKLKEVIRENDHLYFIFEYMKENLYQLIKERNKLFPESAIRNIMYQILQGLAFIHK 118
Query: 540 IGLAHRDMKLDNCVINNQGIVKLIDFG-AAEVFSYPHSKTLIESSGIVGSDPYLAPEVCI 598
+G HRD+K +N + +VK+ DFG A E+ S P + V + Y APEV +
Sbjct: 119 LGFFHRDLKPENLLCMGPELVKIADFGLAREIRSKP------PYTDYVSTRWYRAPEVLL 172
Query: 599 FTKYDPRPVDIWSVAILFA 617
+ P+D+W+V + A
Sbjct: 173 RSTNYSSPIDVWAVGCIMA 191
>Hs21361433 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 970
Score = 86.7 bits (213), Expect = 1e-16
Identities = 57/213 (26%), Positives = 101/213 (46%), Gaps = 10/213 (4%)
Query: 424 KTGENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLRHP 483
K G LG G+ V + I A+K K + K V+++ +E I L+HP
Sbjct: 13 KVGNLLGKGSFAGVYRAESIHSGLEVAIKMIDKKAMY--KAGMVQRVQNEVKIHCQLKHP 70
Query: 484 NIISTIEIVYENNRIFQVMEYCDYDLFAIVMSNKM---SYEEICCCFKQILTGVEYLHSI 540
+I+ ++N ++ V+E C + N++ S E QI+TG+ YLHS
Sbjct: 71 SILELYNYFEDSNYVYLVLEMCHNGEMNRYLKNRVKPFSENEARHFMHQIITGMLYLHSH 130
Query: 541 GLAHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFT 600
G+ HRD+ L N ++ +K+ DFG A PH K + G+ Y++PE+ +
Sbjct: 131 GILHRDLTLSNLLLTRNMNIKIADFGLATQLKMPHEKHYT----LCGTPNYISPEIATRS 186
Query: 601 KYDPRPVDIWSVAILFACMVLKKFPWKIPKLKD 633
+ D+WS+ +F +++ + P+ +K+
Sbjct: 187 AHGLES-DVWSLGCMFYTLLIGRPPFDTDTVKN 218
>Hs20545245 [D] KOG0588 Serine/threonine protein kinase
Length = 795
Score = 86.7 bits (213), Expect = 1e-16
Identities = 72/304 (23%), Positives = 135/304 (43%), Gaps = 60/304 (19%)
Query: 427 ENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLRHPNII 486
+ LG G G V+L Q A+K + ES + K+ E I + HP+++
Sbjct: 55 KTLGKGQTGLVKLGVHCITGQKVAIKIVNREKLSES---VLMKVEREIAILKLIEHPHVL 111
Query: 487 STIEIVYENNR-IFQVMEYCDY-DLFA-IVMSNKMSYEEICCCFKQILTGVEYLHSIGLA 543
+ VYEN + ++ V+E+ +LF +V +++ +E F+QI++ +++ HS +
Sbjct: 112 K-LHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIVSALDFCHSYSIC 170
Query: 544 HRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFTKYD 603
HRD+K +N +++ + +++ DFG A S +L+E+S GS Y PEV KYD
Sbjct: 171 HRDLKPENLLLDEKNNIRIADFGMA---SLQVGDSLLETS--CGSPHYACPEVIKGEKYD 225
Query: 604 PRPVDIWSVAILFACMVLKKFPWKIPKLKDNSFKFFCSGRDCDSLSALVTKTPKPPSYDN 663
R D+WS ++ +++ P+ D D+L L+ K +
Sbjct: 226 GRRADMWSCGVILFALLVGALPF-----------------DDDNLRQLLEKVKR------ 262
Query: 664 AVQSDEPAESTSKSNNPSDPNNTNIGPQRLLHSLPEETHHIIGRMVDLAPACRANIEEVL 723
G + H +P + ++ M+++ P R ++E++
Sbjct: 263 -------------------------GVFHMPHFIPPDCQSLLRGMIEVEPEKRLSLEQIQ 297
Query: 724 NDPW 727
PW
Sbjct: 298 KHPW 301
>Hs16357498 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 777
Score = 86.7 bits (213), Expect = 1e-16
Identities = 63/198 (31%), Positives = 105/198 (52%), Gaps = 15/198 (7%)
Query: 432 GAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLR--HPNIISTI 489
G G V K +++ A+K + + E E ITS I T L+ HPNI++
Sbjct: 429 GTYGVVYRAKDKKTDEIVALKRLKMEKEKEGF-----PITSLREINTILKAQHPNIVTVR 483
Query: 490 EIVYENN--RIFQVMEYCDYDLFAIVMSNKMSY--EEICCCFKQILTGVEYLHSIGLAHR 545
EIV +N +I+ VM Y ++DL +++ + K + E+ Q+L GV++LH + HR
Sbjct: 484 EIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHR 543
Query: 546 DMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFTKYDPR 605
D+K N ++++ GI+K+ DFG A + P L + +V + Y APE+ + K
Sbjct: 544 DLKTSNLLLSHAGILKVGDFGLAREYGSP----LKAYTPVVVTQWYRAPELLLGAKEYST 599
Query: 606 PVDIWSVAILFACMVLKK 623
VD+WSV +F ++ +K
Sbjct: 600 AVDMWSVGCIFGELLTQK 617
>Hs16357486 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 780
Score = 86.7 bits (213), Expect = 1e-16
Identities = 63/198 (31%), Positives = 105/198 (52%), Gaps = 15/198 (7%)
Query: 432 GAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLR--HPNIISTI 489
G G V K +++ A+K + + E E ITS I T L+ HPNI++
Sbjct: 432 GTYGVVYRAKDKKTDEIVALKRLKMEKEKEGF-----PITSLREINTILKAQHPNIVTVR 486
Query: 490 EIVYENN--RIFQVMEYCDYDLFAIVMSNKMSY--EEICCCFKQILTGVEYLHSIGLAHR 545
EIV +N +I+ VM Y ++DL +++ + K + E+ Q+L GV++LH + HR
Sbjct: 487 EIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHR 546
Query: 546 DMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFTKYDPR 605
D+K N ++++ GI+K+ DFG A + P L + +V + Y APE+ + K
Sbjct: 547 DLKTSNLLLSHAGILKVGDFGLAREYGSP----LKAYTPVVVTQWYRAPELLLGAKEYST 602
Query: 606 PVDIWSVAILFACMVLKK 623
VD+WSV +F ++ +K
Sbjct: 603 AVDMWSVGCIFGELLTQK 620
>Hs16357484 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 767
Score = 86.7 bits (213), Expect = 1e-16
Identities = 63/198 (31%), Positives = 105/198 (52%), Gaps = 15/198 (7%)
Query: 432 GAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLR--HPNIISTI 489
G G V K +++ A+K + + E E ITS I T L+ HPNI++
Sbjct: 419 GTYGVVYRAKDKKTDEIVALKRLKMEKEKEGF-----PITSLREINTILKAQHPNIVTVR 473
Query: 490 EIVYENN--RIFQVMEYCDYDLFAIVMSNKMSY--EEICCCFKQILTGVEYLHSIGLAHR 545
EIV +N +I+ VM Y ++DL +++ + K + E+ Q+L GV++LH + HR
Sbjct: 474 EIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHR 533
Query: 546 DMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFTKYDPR 605
D+K N ++++ GI+K+ DFG A + P L + +V + Y APE+ + K
Sbjct: 534 DLKTSNLLLSHAGILKVGDFGLAREYGSP----LKAYTPVVVTQWYRAPELLLGAKEYST 589
Query: 606 PVDIWSVAILFACMVLKK 623
VD+WSV +F ++ +K
Sbjct: 590 AVDMWSVGCIFGELLTQK 607
>Hs16357482 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 776
Score = 86.7 bits (213), Expect = 1e-16
Identities = 63/198 (31%), Positives = 105/198 (52%), Gaps = 15/198 (7%)
Query: 432 GAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLR--HPNIISTI 489
G G V K +++ A+K + + E E ITS I T L+ HPNI++
Sbjct: 428 GTYGVVYRAKDKKTDEIVALKRLKMEKEKEGF-----PITSLREINTILKAQHPNIVTVR 482
Query: 490 EIVYENN--RIFQVMEYCDYDLFAIVMSNKMSY--EEICCCFKQILTGVEYLHSIGLAHR 545
EIV +N +I+ VM Y ++DL +++ + K + E+ Q+L GV++LH + HR
Sbjct: 483 EIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHR 542
Query: 546 DMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFTKYDPR 605
D+K N ++++ GI+K+ DFG A + P L + +V + Y APE+ + K
Sbjct: 543 DLKTSNLLLSHAGILKVGDFGLAREYGSP----LKAYTPVVVTQWYRAPELLLGAKEYST 598
Query: 606 PVDIWSVAILFACMVLKK 623
VD+WSV +F ++ +K
Sbjct: 599 AVDMWSVGCIFGELLTQK 616
>Hs16357480 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 397
Score = 86.7 bits (213), Expect = 1e-16
Identities = 63/198 (31%), Positives = 105/198 (52%), Gaps = 15/198 (7%)
Query: 432 GAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLR--HPNIISTI 489
G G V K +++ A+K + + E E ITS I T L+ HPNI++
Sbjct: 49 GTYGVVYRAKDKKTDEIVALKRLKMEKEKEGF-----PITSLREINTILKAQHPNIVTVR 103
Query: 490 EIVYENN--RIFQVMEYCDYDLFAIVMSNKMSY--EEICCCFKQILTGVEYLHSIGLAHR 545
EIV +N +I+ VM Y ++DL +++ + K + E+ Q+L GV++LH + HR
Sbjct: 104 EIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHR 163
Query: 546 DMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFTKYDPR 605
D+K N ++++ GI+K+ DFG A + P L + +V + Y APE+ + K
Sbjct: 164 DLKTSNLLLSHAGILKVGDFGLAREYGSP----LKAYTPVVVTQWYRAPELLLGAKEYST 219
Query: 606 PVDIWSVAILFACMVLKK 623
VD+WSV +F ++ +K
Sbjct: 220 AVDMWSVGCIFGELLTQK 237
>ECU08g1790 [D] KOG0600 Cdc2-related protein kinase
Length = 309
Score = 86.7 bits (213), Expect = 1e-16
Identities = 65/206 (31%), Positives = 101/206 (48%), Gaps = 20/206 (9%)
Query: 427 ENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLRHPNII 486
+ +G GA G V +R SD VFA+K+ E +++I + C +H II
Sbjct: 8 KQVGEGAFGQVYKSRRTSDGAVFAIKKMPVDRETGFPFTAIREI--KLCKSVINKH--II 63
Query: 487 STIEIVYENNRIFQVMEYCDYDLFAIVMSN-KMSYEEICCCFKQILTGVEYLHSIGLAHR 545
EIV+E IF V+EY YDL ++ S K+S ++I Q++ V +H +GL HR
Sbjct: 64 GLDEIVFEEGFIFVVLEYMPYDLTGLLASGAKLSTDQIRSITSQLIEAVSSMHGMGLVHR 123
Query: 546 DMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDP----YLAPEVCIFTK 601
D+K N +++ G++KL DFG E SG++ + Y APE+ +
Sbjct: 124 DIKPSNILLDCHGMLKLTDFGLTR-----------EISGMMTNRVCTLWYRAPELLLGET 172
Query: 602 YDPRPVDIWSVAILFACMVLKKFPWK 627
VD WSV + M L + P++
Sbjct: 173 SYSLKVDAWSVGCIMLEMRLGRPPYR 198
>At4g40010 [T] KOG0583 Serine/threonine protein kinase
Length = 350
Score = 86.7 bits (213), Expect = 1e-16
Identities = 61/209 (29%), Positives = 110/209 (52%), Gaps = 19/209 (9%)
Query: 428 NLGAGAGGSVRLMKRISDNQVFAVK--EFRPKFEHESKRDYVKKITSEYCIGTTLRHPNI 485
+LG+G G +L++ ++ + +AVK E K + +R+ + L+HPNI
Sbjct: 9 DLGSGNFGVAKLVREKANGEFYAVKYIERGLKIDEHVQREIINH--------RDLKHPNI 60
Query: 486 ISTIEIVYENNRIFQVMEYC-DYDLFA-IVMSNKMSYEEICCCFKQILTGVEYLHSIGLA 543
I E+ + VMEY +LF I + + S +E FKQ+++GV Y H++ +
Sbjct: 61 IRFKEVFVTPTHLAIVMEYAAGGELFERICNAGRFSEDEGRYYFKQLISGVSYCHAMQIC 120
Query: 544 HRDMKLDNCVINN--QGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFTK 601
HRD+KL+N +++ +K+ DFG ++ S HS + VG+ Y+APEV +
Sbjct: 121 HRDLKLENTLLDGSPSSHLKICDFGYSK-SSVLHS----QPKSTVGTPAYVAPEVLSRKE 175
Query: 602 YDPRPVDIWSVAILFACMVLKKFPWKIPK 630
Y+ + D+WS + M++ +P++ P+
Sbjct: 176 YNGKIADVWSCGVTLYVMLVGAYPFEDPE 204
>At3g01090 [T] KOG0583 Serine/threonine protein kinase
Length = 512
Score = 86.7 bits (213), Expect = 1e-16
Identities = 65/214 (30%), Positives = 107/214 (49%), Gaps = 14/214 (6%)
Query: 424 KTGENLGAGAGGSVRLMKRISDNQVFAVKEF-RPKFEHESKRDYVKKITSEYCIGTTLRH 482
K G LG G+ G V++ + A+K R K ++ + V++ E I H
Sbjct: 20 KLGRTLGIGSFGRVKIAEHALTGHKVAIKILNRRKIKNMEMEEKVRR---EIKILRLFMH 76
Query: 483 PNIISTIEIVYENNRIFQVMEYCDY-DLFA-IVMSNKMSYEEICCCFKQILTGVEYLHSI 540
P+II E++ I+ VMEY + +LF IV ++ +E F+QI++GVEY H
Sbjct: 77 PHIIRLYEVIETPTDIYLVMEYVNSGELFDYIVEKGRLQEDEARNFFQQIISGVEYCHRN 136
Query: 541 GLAHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFT 600
+ HRD+K +N +++++ VK+ DFG + + H +++S GS Y APEV
Sbjct: 137 MVVHRDLKPENLLLDSKCNVKIADFGLSNIMRDGH---FLKTS--CGSPNYAAPEVISGK 191
Query: 601 KYDPRPVDIWSVAILFACMVLKKFPW---KIPKL 631
Y VD+WS ++ ++ P+ IP L
Sbjct: 192 LYAGPEVDVWSCGVILYALLCGTLPFDDENIPNL 225
>At1g73670 [T] KOG0660 Mitogen-activated protein kinase
Length = 576
Score = 86.7 bits (213), Expect = 1e-16
Identities = 85/325 (26%), Positives = 144/325 (44%), Gaps = 34/325 (10%)
Query: 427 ENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLRHPNII 486
E +G G+ G V + A+K+ F+H S +I E + L HP+++
Sbjct: 94 EVVGKGSYGVVGSAIDTHTGERVAIKKINDVFDHISD---ATRILREIKLLRLLLHPDVV 150
Query: 487 STIEIVYENNR-----IFQVMEYCDYDLFAIVMSNK-MSYEEICCCFKQILTGVEYLHSI 540
I+ +R ++ V E + DL ++ +N ++ E Q+L G++Y+H+
Sbjct: 151 EIKHIMLPPSRREFRDVYVVFELMESDLHQVIKANDDLTPEHHQFFLYQLLRGLKYVHAA 210
Query: 541 GLAHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVC--I 598
+ HRD+K N + N +K+ DFG A V S+ + T I + V + Y APE+C
Sbjct: 211 NVFHRDLKPKNILANADCKLKICDFGLARV-SFNDAPTAIFWTDYVATRWYRAPELCGSF 269
Query: 599 FTKYDPRPVDIWSVAILFACMVLKK--FPWKIPKLKDNSFKFFCSGRDCDSLSALVTKTP 656
F+KY P +DIWSV +FA M+L K FP K + + F +++S + +
Sbjct: 270 FSKYTP-AIDIWSVGCIFAEMLLGKPLFPGKNVVHQLDIMTDFLGTPPPEAISKI--RND 326
Query: 657 KPPSYDNAVQSDEPAESTSKSNNPSDPNNTNIGPQRLLHSLPEETHHIIGRMVDLAPACR 716
K Y ++ +P SK +DP+ ++ R++ P R
Sbjct: 327 KARRYLGNMRKKQPV-PFSKKFPKADPS----------------ALRLLERLIAFDPKDR 369
Query: 717 ANIEEVLNDPWIQSIDMCTVEVDNQ 741
+ EE L DP+ + E Q
Sbjct: 370 PSAEEALADPYFNGLSSKVREPSTQ 394
>At1g30270 [T] KOG0583 Serine/threonine protein kinase
Length = 480
Score = 86.7 bits (213), Expect = 1e-16
Identities = 59/223 (26%), Positives = 108/223 (47%), Gaps = 10/223 (4%)
Query: 426 GENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLRHPNI 485
G LG G V+ + + + A+K E K + +I E ++HPN+
Sbjct: 34 GRTLGEGTFAKVKFARNVENGDNVAIKVIDK--EKVLKNKMIAQIKREISTMKLIKHPNV 91
Query: 486 ISTIEIVYENNRIFQVMEYCDY-DLFAIVMSN-KMSYEEICCCFKQILTGVEYLHSIGLA 543
I E++ +I+ V+E+ +LF + SN ++ +E F+Q++ V+Y HS G+
Sbjct: 92 IRMFEVMASKTKIYFVLEFVTGGELFDKISSNGRLKEDEARKYFQQLINAVDYCHSRGVY 151
Query: 544 HRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKT-LIESSGIVGSDPYLAPEVCIFTKY 602
HRD+K +N +++ G +K+ DFG + + P + L+ ++ G+ Y+APEV Y
Sbjct: 152 HRDLKPENLLLDANGALKVSDFGLS---ALPQQEDGLLHTT--CGTPNYVAPEVINNKGY 206
Query: 603 DPRPVDIWSVAILFACMVLKKFPWKIPKLKDNSFKFFCSGRDC 645
D D+WS ++ ++ P++ L K F + C
Sbjct: 207 DGAKADLWSCGVILFVLMAGYLPFEDSNLTSLYKKIFKAEFTC 249
>SPAC644.06c [D] KOG0588 Serine/threonine protein kinase
Length = 593
Score = 86.3 bits (212), Expect = 2e-16
Identities = 78/308 (25%), Positives = 128/308 (41%), Gaps = 65/308 (21%)
Query: 424 KTGENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLRHP 483
+ G+ LG G+ VRL K + A+K ++ I E + LRHP
Sbjct: 13 RLGKTLGTGSTSCVRLAKHAKTGDLAAIKIIPIRYA---------SIGMEILMMRLLRHP 63
Query: 484 NIISTIEIVYENNRIFQVMEYC-DYDLFAIVMSN-KMSYEEICCCFKQILTGVEYLHSIG 541
NI+ ++ ++ ++ +EY D +LF + + +S E QIL V + H
Sbjct: 64 NILRLYDVWTDHQHMYLALEYVPDGELFHYIRKHGPLSEREAAHYLSQILDAVAHCHRFR 123
Query: 542 LAHRDMKLDNCVIN-NQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFT 600
HRD+KL+N +I N+ +K+ DFG A V P+ L GS YLAPE+
Sbjct: 124 FRHRDLKLENILIKVNEQQIKIADFGMATV--EPNDSCL---ENYCGSLHYLAPEIVSHK 178
Query: 601 KYDPRPVDIWSVAILFACMVLKKFPWKIPKLKDNSFKFFCSGRDCDSLSALVTKTPKPPS 660
Y P D+WS ++ ++ K P+ G++ D ++ + +
Sbjct: 179 PYRGAPADVWSCGVILYSLLSNKLPF--------------GGQNTD----VIYNKIRHGA 220
Query: 661 YDNAVQSDEPAESTSKSNNPSDPNNTNIGPQRLLHSLPEETHHIIGRMVDLAPACRANIE 720
YD P++ + Q LLH RM+D+ P+ R I
Sbjct: 221 YDL-------------------PSSISSAAQDLLH-----------RMLDVNPSTRITIP 250
Query: 721 EVLNDPWI 728
EV + P++
Sbjct: 251 EVFSHPFL 258
>HsM7657627 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 970
Score = 86.3 bits (212), Expect = 2e-16
Identities = 57/213 (26%), Positives = 101/213 (46%), Gaps = 10/213 (4%)
Query: 424 KTGENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLRHP 483
K G LG G+ V + I A+K K + K V+++ +E I L+HP
Sbjct: 13 KVGNLLGKGSFAGVYRAESIHTGLEVAIKMIDKKAMY--KAGMVQRVKNEVKIHCQLKHP 70
Query: 484 NIISTIEIVYENNRIFQVMEYCDYDLFAIVMSNKM---SYEEICCCFKQILTGVEYLHSI 540
+I+ ++N ++ V+E C + N++ S E QI+TG+ YLHS
Sbjct: 71 SILELYNYFEDSNYVYLVLEMCHNGEMNRYLKNRVKPFSENEARHFMHQIITGMLYLHSH 130
Query: 541 GLAHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFT 600
G+ HRD+ L N ++ +K+ DFG A PH K + G+ Y++PE+ +
Sbjct: 131 GILHRDLTLSNLLLTRNMNIKIADFGLATQLKMPHEKHYT----LCGTPNYISPEIATRS 186
Query: 601 KYDPRPVDIWSVAILFACMVLKKFPWKIPKLKD 633
+ D+WS+ +F +++ + P+ +K+
Sbjct: 187 AHGLES-DVWSLGCMFYTLLIGRPPFDTDTVKN 218
>Hs4505601 [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 544
Score = 86.3 bits (212), Expect = 2e-16
Identities = 63/208 (30%), Positives = 106/208 (50%), Gaps = 12/208 (5%)
Query: 420 KRYLKTGENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTT 479
K+Y + E +G GA G+V I+ Q A+K+ + + K++ I +E +
Sbjct: 266 KKYTRF-EKIGQGASGTVYTALDIATGQEVAIKQMN--LQQQPKKEL---IINEILVMRE 319
Query: 480 LRHPNIISTIEIVYENNRIFQVMEY-CDYDLFAIVMSNKMSYEEICCCFKQILTGVEYLH 538
++PNI++ ++ + ++ VMEY L +V M +I ++ L +++LH
Sbjct: 320 NKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALDFLH 379
Query: 539 SIGLAHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCI 598
S + HRD+K DN ++ G VKL DFG + SK S +VG+ ++APEV
Sbjct: 380 SNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSK----RSTMVGTPYWMAPEVVT 435
Query: 599 FTKYDPRPVDIWSVAILFACMVLKKFPW 626
Y P+ VDIWS+ I+ MV + P+
Sbjct: 436 RKAYGPK-VDIWSLGIMAIEMVEGEPPY 462
>Hs16357496 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 439
Score = 86.3 bits (212), Expect = 2e-16
Identities = 66/204 (32%), Positives = 108/204 (52%), Gaps = 17/204 (8%)
Query: 432 GAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLR--HPNIISTI 489
G G V K +++ A+K + + E E ITS I T L+ HPNI++
Sbjct: 91 GTYGVVYRAKDKKTDEIVALKRLKMEKEKEGF-----PITSLREINTILKAQHPNIVTVR 145
Query: 490 EIVYENN--RIFQVMEYCDYDLFAIVMSNKMSY--EEICCCFKQILTGVEYLHSIGLAHR 545
EIV +N +I+ VM Y ++DL +++ + K + E+ Q+L GV++LH + HR
Sbjct: 146 EIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHR 205
Query: 546 DMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFTKYDPR 605
D+K N ++++ GI+K+ DFG A + P L + +V + Y APE+ + K
Sbjct: 206 DLKTSNLLLSHAGILKVGDFGLAREYGSP----LKAYTPVVVTLWYRAPELLLGAKEYST 261
Query: 606 PVDIWSVAILFACMVLKK--FPWK 627
VD+WSV +F ++ +K FP K
Sbjct: 262 AVDMWSVGCIFGELLTQKPLFPGK 285
>Hs16332372 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 771
Score = 86.3 bits (212), Expect = 2e-16
Identities = 66/204 (32%), Positives = 108/204 (52%), Gaps = 17/204 (8%)
Query: 432 GAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLR--HPNIISTI 489
G G V K +++ A+K + + E E ITS I T L+ HPNI++
Sbjct: 423 GTYGVVYRAKDKKTDEIVALKRLKMEKEKEGF-----PITSLREINTILKAQHPNIVTVR 477
Query: 490 EIVYENN--RIFQVMEYCDYDLFAIVMSNKMSY--EEICCCFKQILTGVEYLHSIGLAHR 545
EIV +N +I+ VM Y ++DL +++ + K + E+ Q+L GV++LH + HR
Sbjct: 478 EIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHR 537
Query: 546 DMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFTKYDPR 605
D+K N ++++ GI+K+ DFG A + P L + +V + Y APE+ + K
Sbjct: 538 DLKTSNLLLSHAGILKVGDFGLAREYGSP----LKAYTPVVVTLWYRAPELLLGAKEYST 593
Query: 606 PVDIWSVAILFACMVLKK--FPWK 627
VD+WSV +F ++ +K FP K
Sbjct: 594 AVDMWSVGCIFGELLTQKPLFPGK 617
>Hs16332370 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 780
Score = 86.3 bits (212), Expect = 2e-16
Identities = 66/204 (32%), Positives = 108/204 (52%), Gaps = 17/204 (8%)
Query: 432 GAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLR--HPNIISTI 489
G G V K +++ A+K + + E E ITS I T L+ HPNI++
Sbjct: 432 GTYGVVYRAKDKKTDEIVALKRLKMEKEKEGF-----PITSLREINTILKAQHPNIVTVR 486
Query: 490 EIVYENN--RIFQVMEYCDYDLFAIVMSNKMSY--EEICCCFKQILTGVEYLHSIGLAHR 545
EIV +N +I+ VM Y ++DL +++ + K + E+ Q+L GV++LH + HR
Sbjct: 487 EIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHR 546
Query: 546 DMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFTKYDPR 605
D+K N ++++ GI+K+ DFG A + P L + +V + Y APE+ + K
Sbjct: 547 DLKTSNLLLSHAGILKVGDFGLAREYGSP----LKAYTPVVVTLWYRAPELLLGAKEYST 602
Query: 606 PVDIWSVAILFACMVLKK--FPWK 627
VD+WSV +F ++ +K FP K
Sbjct: 603 AVDMWSVGCIFGELLTQKPLFPGK 626
>Hs16332368 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 461
Score = 86.3 bits (212), Expect = 2e-16
Identities = 66/204 (32%), Positives = 108/204 (52%), Gaps = 17/204 (8%)
Query: 432 GAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLR--HPNIISTI 489
G G V K +++ A+K + + E E ITS I T L+ HPNI++
Sbjct: 113 GTYGVVYRAKDKKTDEIVALKRLKMEKEKEGF-----PITSLREINTILKAQHPNIVTVR 167
Query: 490 EIVYENN--RIFQVMEYCDYDLFAIVMSNKMSY--EEICCCFKQILTGVEYLHSIGLAHR 545
EIV +N +I+ VM Y ++DL +++ + K + E+ Q+L GV++LH + HR
Sbjct: 168 EIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHR 227
Query: 546 DMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFTKYDPR 605
D+K N ++++ GI+K+ DFG A + P L + +V + Y APE+ + K
Sbjct: 228 DLKTSNLLLSHAGILKVGDFGLAREYGSP----LKAYTPVVVTLWYRAPELLLGAKEYST 283
Query: 606 PVDIWSVAILFACMVLKK--FPWK 627
VD+WSV +F ++ +K FP K
Sbjct: 284 AVDMWSVGCIFGELLTQKPLFPGK 307
>Hs16332366 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 565
Score = 86.3 bits (212), Expect = 2e-16
Identities = 66/204 (32%), Positives = 108/204 (52%), Gaps = 17/204 (8%)
Query: 432 GAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLR--HPNIISTI 489
G G V K +++ A+K + + E E ITS I T L+ HPNI++
Sbjct: 217 GTYGVVYRAKDKKTDEIVALKRLKMEKEKEGF-----PITSLREINTILKAQHPNIVTVR 271
Query: 490 EIVYENN--RIFQVMEYCDYDLFAIVMSNKMSY--EEICCCFKQILTGVEYLHSIGLAHR 545
EIV +N +I+ VM Y ++DL +++ + K + E+ Q+L GV++LH + HR
Sbjct: 272 EIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHR 331
Query: 546 DMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFTKYDPR 605
D+K N ++++ GI+K+ DFG A + P L + +V + Y APE+ + K
Sbjct: 332 DLKTSNLLLSHAGILKVGDFGLAREYGSP----LKAYTPVVVTLWYRAPELLLGAKEYST 387
Query: 606 PVDIWSVAILFACMVLKK--FPWK 627
VD+WSV +F ++ +K FP K
Sbjct: 388 AVDMWSVGCIFGELLTQKPLFPGK 411
>Hs16332364 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 748
Score = 86.3 bits (212), Expect = 2e-16
Identities = 66/204 (32%), Positives = 108/204 (52%), Gaps = 17/204 (8%)
Query: 432 GAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLR--HPNIISTI 489
G G V K +++ A+K + + E E ITS I T L+ HPNI++
Sbjct: 400 GTYGVVYRAKDKKTDEIVALKRLKMEKEKEGF-----PITSLREINTILKAQHPNIVTVR 454
Query: 490 EIVYENN--RIFQVMEYCDYDLFAIVMSNKMSY--EEICCCFKQILTGVEYLHSIGLAHR 545
EIV +N +I+ VM Y ++DL +++ + K + E+ Q+L GV++LH + HR
Sbjct: 455 EIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHR 514
Query: 546 DMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFTKYDPR 605
D+K N ++++ GI+K+ DFG A + P L + +V + Y APE+ + K
Sbjct: 515 DLKTSNLLLSHAGILKVGDFGLAREYGSP----LKAYTPVVVTLWYRAPELLLGAKEYST 570
Query: 606 PVDIWSVAILFACMVLKK--FPWK 627
VD+WSV +F ++ +K FP K
Sbjct: 571 AVDMWSVGCIFGELLTQKPLFPGK 594
>Hs16332362 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 737
Score = 86.3 bits (212), Expect = 2e-16
Identities = 66/204 (32%), Positives = 108/204 (52%), Gaps = 17/204 (8%)
Query: 432 GAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLR--HPNIISTI 489
G G V K +++ A+K + + E E ITS I T L+ HPNI++
Sbjct: 389 GTYGVVYRAKDKKTDEIVALKRLKMEKEKEGF-----PITSLREINTILKAQHPNIVTVR 443
Query: 490 EIVYENN--RIFQVMEYCDYDLFAIVMSNKMSY--EEICCCFKQILTGVEYLHSIGLAHR 545
EIV +N +I+ VM Y ++DL +++ + K + E+ Q+L GV++LH + HR
Sbjct: 444 EIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHR 503
Query: 546 DMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFTKYDPR 605
D+K N ++++ GI+K+ DFG A + P L + +V + Y APE+ + K
Sbjct: 504 DLKTSNLLLSHAGILKVGDFGLAREYGSP----LKAYTPVVVTLWYRAPELLLGAKEYST 559
Query: 606 PVDIWSVAILFACMVLKK--FPWK 627
VD+WSV +F ++ +K FP K
Sbjct: 560 AVDMWSVGCIFGELLTQKPLFPGK 583
>Hs16332360 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 526
Score = 86.3 bits (212), Expect = 2e-16
Identities = 66/204 (32%), Positives = 108/204 (52%), Gaps = 17/204 (8%)
Query: 432 GAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLR--HPNIISTI 489
G G V K +++ A+K + + E E ITS I T L+ HPNI++
Sbjct: 178 GTYGVVYRAKDKKTDEIVALKRLKMEKEKEGF-----PITSLREINTILKAQHPNIVTVR 232
Query: 490 EIVYENN--RIFQVMEYCDYDLFAIVMSNKMSY--EEICCCFKQILTGVEYLHSIGLAHR 545
EIV +N +I+ VM Y ++DL +++ + K + E+ Q+L GV++LH + HR
Sbjct: 233 EIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHR 292
Query: 546 DMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFTKYDPR 605
D+K N ++++ GI+K+ DFG A + P L + +V + Y APE+ + K
Sbjct: 293 DLKTSNLLLSHAGILKVGDFGLAREYGSP----LKAYTPVVVTLWYRAPELLLGAKEYST 348
Query: 606 PVDIWSVAILFACMVLKK--FPWK 627
VD+WSV +F ++ +K FP K
Sbjct: 349 AVDMWSVGCIFGELLTQKPLFPGK 372
>Hs16332358 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 782
Score = 86.3 bits (212), Expect = 2e-16
Identities = 66/204 (32%), Positives = 108/204 (52%), Gaps = 17/204 (8%)
Query: 432 GAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLR--HPNIISTI 489
G G V K +++ A+K + + E E ITS I T L+ HPNI++
Sbjct: 434 GTYGVVYRAKDKKTDEIVALKRLKMEKEKEGF-----PITSLREINTILKAQHPNIVTVR 488
Query: 490 EIVYENN--RIFQVMEYCDYDLFAIVMSNKMSY--EEICCCFKQILTGVEYLHSIGLAHR 545
EIV +N +I+ VM Y ++DL +++ + K + E+ Q+L GV++LH + HR
Sbjct: 489 EIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHR 548
Query: 546 DMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFTKYDPR 605
D+K N ++++ GI+K+ DFG A + P L + +V + Y APE+ + K
Sbjct: 549 DLKTSNLLLSHAGILKVGDFGLAREYGSP----LKAYTPVVVTLWYRAPELLLGAKEYST 604
Query: 606 PVDIWSVAILFACMVLKK--FPWK 627
VD+WSV +F ++ +K FP K
Sbjct: 605 AVDMWSVGCIFGELLTQKPLFPGK 628
>Hs10835055 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 795
Score = 86.3 bits (212), Expect = 2e-16
Identities = 66/204 (32%), Positives = 108/204 (52%), Gaps = 17/204 (8%)
Query: 432 GAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLR--HPNIISTI 489
G G V K +++ A+K + + E E ITS I T L+ HPNI++
Sbjct: 447 GTYGVVYRAKDKKTDEIVALKRLKMEKEKEGF-----PITSLREINTILKAQHPNIVTVR 501
Query: 490 EIVYENN--RIFQVMEYCDYDLFAIVMSNKMSY--EEICCCFKQILTGVEYLHSIGLAHR 545
EIV +N +I+ VM Y ++DL +++ + K + E+ Q+L GV++LH + HR
Sbjct: 502 EIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHR 561
Query: 546 DMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFTKYDPR 605
D+K N ++++ GI+K+ DFG A + P L + +V + Y APE+ + K
Sbjct: 562 DLKTSNLLLSHAGILKVGDFGLAREYGSP----LKAYTPVVVTLWYRAPELLLGAKEYST 617
Query: 606 PVDIWSVAILFACMVLKK--FPWK 627
VD+WSV +F ++ +K FP K
Sbjct: 618 AVDMWSVGCIFGELLTQKPLFPGK 641
>YPL141c [T] KOG0583 Serine/threonine protein kinase
Length = 865
Score = 85.9 bits (211), Expect = 2e-16
Identities = 69/216 (31%), Positives = 102/216 (46%), Gaps = 22/216 (10%)
Query: 426 GENLGAGAGGSVRL--MKRISD--NQVF------AVKEFRPKFEHESKRDYVK--KITSE 473
G LG G G V+L K S+ N F A+K + DY K KI E
Sbjct: 44 GSTLGEGEFGKVKLGWPKNFSNSSNSTFDFPKQVAIKLIK---RDSISNDYRKEVKIYRE 100
Query: 474 YCIGTTLRHPNIISTIEIVYENNRIFQVMEYCDYDLFAIVMSNKMSYEEICCC--FKQIL 531
L HPNI+ E++ + I V+EY F + K +E+ C F Q++
Sbjct: 101 INALKHLSHPNIVKLEEVLQNSRYIGIVLEYACGGEFYKYIQKKRRLKEMNACRLFSQLI 160
Query: 532 TGVEYLHSIGLAHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPY 591
+GV Y+HS GL HRD+KL+N +++ + + DFG F L+++S GS Y
Sbjct: 161 SGVHYIHSKGLVHRDLKLENLLLDKNENLVITDFGFVNEFC--SRNELMKTS--CGSPCY 216
Query: 592 LAPEVCIFTK-YDPRPVDIWSVAILFACMVLKKFPW 626
APE+ I + Y+ R DIWS ++ ++ PW
Sbjct: 217 AAPELVISAEPYEARKADIWSCGVILYAILAGYLPW 252
>SPCC4G3.08 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 436
Score = 85.9 bits (211), Expect = 2e-16
Identities = 64/241 (26%), Positives = 122/241 (50%), Gaps = 20/241 (8%)
Query: 429 LGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLRHPNIIST 488
LG G+ G V L+K+ + ++FA K+ + K + +++ +E I +RHP I
Sbjct: 97 LGRGSYGKVLLVKQKNTGRLFAQKQLK-KASIVLRAKGLEQTKNERQILEEVRHPFICRL 155
Query: 489 IEIVYENNRIFQVMEYCDY-DLFAIVMSNKMSYEEICCCFKQILT-GVEYLHSIGLAHRD 546
+++R++ +++Y +LF+ + +M E++ + LT + +LH +G+ +RD
Sbjct: 156 YYAFQDHDRLYLILQYAPGGELFSHLAEQRMLPEDVVAFYTAELTLALIHLHKLGIVYRD 215
Query: 547 MKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFTKYDPRP 606
+K +NC+++ +G + L DFG ++V ++ + VG++ Y APE+ + YD
Sbjct: 216 LKPENCLLDAEGHILLTDFGLSKV-----AENGADCRSFVGTEEYCAPEILLEQPYD-HA 269
Query: 607 VDIWSVAIL----------FACMVLKKFPWKIPKLKDNSFKFFCSGRDCDSLSALVTKTP 656
VD WS+ IL F K+ KI + K N F+ + D ++ + K P
Sbjct: 270 VDWWSMGILIFDLLTGSPPFTANNHKRIMEKITRAKPN-IPFYVTSDARDIINKFLKKNP 328
Query: 657 K 657
K
Sbjct: 329 K 329
>Hs7706445 [T] KOG0664 Nemo-like MAPK-related serine/threonine protein kinase
Length = 515
Score = 85.9 bits (211), Expect = 2e-16
Identities = 75/306 (24%), Positives = 142/306 (45%), Gaps = 28/306 (9%)
Query: 429 LGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLRHPNIIST 488
+G GA G V + D + A+K+ F++ K++ E + +H N++S
Sbjct: 132 IGYGAFGVVWSVTDPRDGKRVALKKMPNVFQNLVS---CKRVFRELKMLCFFKHDNVLSA 188
Query: 489 IEIVYENN-----RIFQVMEYCDYDLFAIVMSNK-MSYEEICCCFKQILTGVEYLHSIGL 542
++I+ + I+ V E DL I++S + +S + + QIL G++YLHS G+
Sbjct: 189 LDILQPPHIDYFEEIYVVTELMQSDLHKIIVSPQPLSSDHVKVFLYQILRGLKYLHSAGI 248
Query: 543 AHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFTKY 602
HRD+K N ++N+ ++K+ DFG A V S+ + + V + Y APE+ + +++
Sbjct: 249 LHRDIKPGNLLVNSNCVLKICDFGLARVEELDESRHMTQE---VVTQYYRAPEILMGSRH 305
Query: 603 DPRPVDIWSVAILFACMVLKKFPWKIPKLKDNSFKFFCSGRDCDSLSALVTKTPKPPSYD 662
+DIWSV +FA ++ ++ F+ + D ++ L+ TP +
Sbjct: 306 YSNAIDIWSVGCIFAELLGRRI----------LFQAQSPIQQLDLITDLL-GTPSLEAMR 354
Query: 663 NAVQSDEPAESTSKSNNPSDPNNTNIGPQRLLHSLPEETHHIIGRMVDLAPACRANIEEV 722
A + + PS P + Q E H++ RM+ P+ R + ++
Sbjct: 355 TACEGAKAHILRGPHKQPSLPVLYTLSSQ-----ATHEAVHLLCRMLVFDPSKRISAKDA 409
Query: 723 LNDPWI 728
L P++
Sbjct: 410 LAHPYL 415
>Hs5453964 [T] KOG0583 Serine/threonine protein kinase
Length = 550
Score = 85.9 bits (211), Expect = 2e-16
Identities = 71/223 (31%), Positives = 104/223 (45%), Gaps = 18/223 (8%)
Query: 426 GENLGAGAGGSVRLMKRISDNQVFAVKEF-RPKFEHESKRDYVKKITSEYCIGTTLRHPN 484
G+ LG G G V++ K AVK R K D V KI E RHP+
Sbjct: 21 GDTLGVGTFGKVKVGKHELTGHKVAVKILNRQKIR---SLDVVGKIRREIQNLKLFRHPH 77
Query: 485 IISTIEIVYENNRIFQVMEYCDY-DLFAIVMSN-KMSYEEICCCFKQILTGVEYLHSIGL 542
II +++ + IF VMEY +LF + N ++ +E F+QIL+GV+Y H +
Sbjct: 78 IIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYCHRHMV 137
Query: 543 AHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFTKY 602
HRD+K +N +++ K+ DFG + + S + +S GS Y APEV Y
Sbjct: 138 VHRDLKPENVLLDAHMNAKIADFGLSNMMS---DGEFLRTS--CGSPNYAAPEVISGRLY 192
Query: 603 DPRPVDIWSVAILFACMVLKKFPW---KIPKLKDNSFKFFCSG 642
VDIWS ++ ++ P+ +P L FK C G
Sbjct: 193 AGPEVDIWSSGVILYALLCGTLPFDDDHVPTL----FKKICDG 231
>CE16081 [T] KOG0583 Serine/threonine protein kinase
Length = 334
Score = 85.9 bits (211), Expect = 2e-16
Identities = 61/214 (28%), Positives = 107/214 (49%), Gaps = 10/214 (4%)
Query: 422 YLKTGENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLR 481
+ + G+ LGAG V+L + AVK K + ++K K ++ E +
Sbjct: 48 FYRLGKELGAGNFSKVKLGVHQLTKEKVAVK-IMDKAKMDAKAQ--KLLSREIQAMEEMN 104
Query: 482 HPNIISTIEIVYENNRIFQVMEYCDY-DLFAIVMSN-KMSYEEICCCFKQILTGVEYLHS 539
HPNI+ E+V R+ V+EY +L+ V K++ + F QI++ V ++HS
Sbjct: 105 HPNIVKLFEVVETLTRVHLVIEYASGGELYTYVHERGKLTEGDAKPLFAQIVSAVSHMHS 164
Query: 540 IGLAHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIF 599
+ HRD+K +N + ++ VKL+DFG + + + ++ + GS PY APE+
Sbjct: 165 RNIVHRDIKAENVMFSSPNTVKLVDFGFSCLVD---REQMLRT--FCGSPPYAAPELFQD 219
Query: 600 TKYDPRPVDIWSVAILFACMVLKKFPWKIPKLKD 633
T Y VD+W++ +L M++ P+K + D
Sbjct: 220 TSYAGELVDVWALGVLLFFMLIGVTPFKAETVPD 253
>At5g19010 [T] KOG0660 Mitogen-activated protein kinase
Length = 567
Score = 85.9 bits (211), Expect = 2e-16
Identities = 66/211 (31%), Positives = 106/211 (49%), Gaps = 15/211 (7%)
Query: 427 ENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLRHPNII 486
E +G G+ G V + A+K+ FEH S +I E + LRHP+I+
Sbjct: 29 EVIGKGSYGVVCSAYDTHTGEKVAIKKINDIFEHVSD---ATRILREIKLLRLLRHPDIV 85
Query: 487 STIEIVYENNR-----IFQVMEYCDYDLFAIVMSNK-MSYEEICCCFKQILTGVEYLHSI 540
I+ +R I+ V E + DL ++ +N ++ E Q+L G++Y+H+
Sbjct: 86 EIKHILLPPSRREFRDIYVVFELMESDLHQVIKANDDLTPEHYQFFLYQLLRGLKYIHTA 145
Query: 541 GLAHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVC--I 598
+ HRD+K N + N +K+ DFG A V ++ + T I + V + Y APE+C
Sbjct: 146 NVFHRDLKPKNILANADCKLKICDFGLARV-AFNDTPTAIFWTDYVATRWYRAPELCGSF 204
Query: 599 FTKYDPRPVDIWSVAILFACMVLKK--FPWK 627
F+KY P +DIWS+ +FA ++ K FP K
Sbjct: 205 FSKYTP-AIDIWSIGCIFAELLTGKPLFPGK 234
>At5g01810 [T] KOG0583 Serine/threonine protein kinase
Length = 421
Score = 85.9 bits (211), Expect = 2e-16
Identities = 56/211 (26%), Positives = 102/211 (47%), Gaps = 5/211 (2%)
Query: 424 KTGENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLRHP 483
+ G+ LG G V + + A+K E K ++I E LRHP
Sbjct: 13 EVGKFLGQGTFAKVYHARHLKTGDSVAIKVIDK--ERILKVGMTEQIKREISAMRLLRHP 70
Query: 484 NIISTIEIVYENNRIFQVMEYCDY-DLFAIVMSNKMSYEEICCCFKQILTGVEYLHSIGL 542
NI+ E++ ++I+ VME+ +LF V + K+ + F+Q++ V++ HS G+
Sbjct: 71 NIVELHEVMATKSKIYFVMEHVKGGELFNKVSTGKLREDVARKYFQQLVRAVDFCHSRGV 130
Query: 543 AHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFTKY 602
HRD+K +N +++ G +K+ DFG + + L+ ++ G+ Y+APEV Y
Sbjct: 131 CHRDLKPENLLLDEHGNLKISDFGLSALSDSRRQDGLLHTT--CGTPAYVAPEVISRNGY 188
Query: 603 DPRPVDIWSVAILFACMVLKKFPWKIPKLKD 633
D D+WS ++ ++ P++ L +
Sbjct: 189 DGFKADVWSCGVILFVLLAGYLPFRDSNLME 219
>At4g10010 [D] KOG0600 Cdc2-related protein kinase
Length = 649
Score = 85.9 bits (211), Expect = 2e-16
Identities = 61/203 (30%), Positives = 107/203 (52%), Gaps = 14/203 (6%)
Query: 427 ENLGAGAGGSVRLMKRISDNQVFAVKEFR-PKFEHESKRDYVKKITSEYCIGTTLRHPNI 485
+ +G G SV + + ++ A+K+ R + ES R ++I I L HPN+
Sbjct: 160 DKIGQGTYSSVYRARDLETGKMVAMKKVRFVNMDPESVRFMAREIN----ILRKLDHPNV 215
Query: 486 ISTIEIVYE--NNRIFQVMEYCDYDLFAIVMSNKMSYEE--ICCCFKQILTGVEYLHSIG 541
+ +V + ++ V EY ++DL + + + + E I C KQ+L+G+E+ HS G
Sbjct: 216 MKLECLVTSKLSGSLYLVFEYMEHDLSGLALRPGVKFTESQIKCYMKQLLSGLEHCHSRG 275
Query: 542 LAHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCI-FT 600
+ HRD+K N ++NN G++K+ DFG A ++ + L + V + Y APE+ + T
Sbjct: 276 ILHRDIKGPNLLVNNDGVLKIGDFGLANIYHPEQDQPL---TSRVVTLWYRAPELLLGAT 332
Query: 601 KYDPRPVDIWSVAILFACMVLKK 623
+Y P +D+WSV + + L K
Sbjct: 333 EYGP-GIDLWSVGCILTELFLGK 354
>At2g42880 [T] KOG0660 Mitogen-activated protein kinase
Length = 594
Score = 85.9 bits (211), Expect = 2e-16
Identities = 82/318 (25%), Positives = 142/318 (43%), Gaps = 34/318 (10%)
Query: 424 KTGENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLRHP 483
K E +G G+ G V + A+K+ FEH S +I E + LRHP
Sbjct: 14 KVQEVIGKGSYGVVCSAIDTLTGEKVAIKKIHDIFEHISD---AARILREIKLLRLLRHP 70
Query: 484 NIISTIEIVYENNR-----IFQVMEYCDYDLFAIVMSNK-MSYEEICCCFKQILTGVEYL 537
+I+ I+ +R I+ V E + DL ++ +N ++ E Q+L ++Y+
Sbjct: 71 DIVEIKHIMLPPSRREFKDIYVVFELMESDLHQVIKANDDLTREHYQFFLYQLLRALKYI 130
Query: 538 HSIGLAHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVC 597
H+ + HRD+K N + N +K+ DFG A V ++ + T I + V + Y APE+C
Sbjct: 131 HTANVYHRDLKPKNILANANCKLKICDFGLARV-AFNDTPTTIFWTDYVATRWYRAPELC 189
Query: 598 --IFTKYDPRPVDIWSVAILFACMVLKK--FPWKIPKLKDNSFKFFCSGRDCDSLSALVT 653
++KY P +DIWS+ +FA +++ K FP K + + D++S +
Sbjct: 190 GSFYSKYTP-AIDIWSIGCIFAEVLMGKPLFPGKNVVHQLDLMTDLLGTPSLDTISRV-- 246
Query: 654 KTPKPPSYDNAVQSDEPAESTSKSNNPSDPNNTNIGPQRLLHSLPEETHHIIGRMVDLAP 713
+ K Y +++ P K N +DP + ++ R++ P
Sbjct: 247 RNEKARRYLTSMRKKPPIPFAQKFPN-ADPLSLK----------------LLERLLAFDP 289
Query: 714 ACRANIEEVLNDPWIQSI 731
R EE L DP+ + +
Sbjct: 290 KDRPTAEEALADPYFKGL 307
>At2g38490 [T] KOG0583 Serine/threonine protein kinase
Length = 431
Score = 85.9 bits (211), Expect = 2e-16
Identities = 56/208 (26%), Positives = 107/208 (50%), Gaps = 7/208 (3%)
Query: 426 GENLGAGAGGSVRLMKRISDN-QVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLRHPN 484
G+ LG+GA V + + + + A+K + K + +VK+ E + LRHP+
Sbjct: 31 GKLLGSGAFAKVYQAEDLQNGGESVAIKVVQKKRLKDGLTAHVKR---EISVMRRLRHPH 87
Query: 485 IISTIEIVYENNRIFQVMEYCDY-DLFAIVMSNKMSYEEICCCFKQILTGVEYLHSIGLA 543
I+ E++ +I+ VME +LF+ V SN+ + F+Q+++ V Y H+ G+
Sbjct: 88 IVLLSEVLATKTKIYFVMELAKGGELFSRVTSNRFTESLSRKYFRQLISAVRYCHARGVF 147
Query: 544 HRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFTKYD 603
HRD+K +N +++ +K+ DFG + + H ++ + + G+ Y+APE+ + YD
Sbjct: 148 HRDLKPENLLLDENRDLKVSDFGLSAMKEQIHPDGMLHT--LCGTPAYVAPELLLKKGYD 205
Query: 604 PRPVDIWSVAILFACMVLKKFPWKIPKL 631
DIWS ++ + P++ P +
Sbjct: 206 GSKADIWSCGVVLFLLNAGYLPFRDPNI 233
>Hs7662388 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 632
Score = 85.5 bits (210), Expect = 3e-16
Identities = 56/196 (28%), Positives = 97/196 (48%), Gaps = 13/196 (6%)
Query: 425 TGENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLRHPN 484
T LG G GSV L + I ++ A+K+ + KF + ++++ S L H N
Sbjct: 6 TIRQLGDGTYGSVLLGRSIESGELIAIKKMKRKFYSWEECMNLREVKSL----KKLNHAN 61
Query: 485 IISTIEIVYENNRIFQVMEYCDYDLFAIVMSNKMSYEE--ICCCFKQILTGVEYLHSIGL 542
++ E++ EN+ ++ + EY +L+ ++ + E I QIL G+ ++H G
Sbjct: 62 VVKLKEVIRENDHLYFIFEYMKENLYQLIKERNKLFPESAIRNIMYQILQGLAFIHKHGF 121
Query: 543 AHRDMKLDNCVINNQGIVKLIDFG-AAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFTK 601
HRD+K +N + +VK+ DFG A E+ S P + V + Y APEV + +
Sbjct: 122 FHRDLKPENLLCMGPELVKIADFGLAREIRSKP------PYTDYVSTRWYRAPEVLLRST 175
Query: 602 YDPRPVDIWSVAILFA 617
P+D+W+V + A
Sbjct: 176 NYSSPIDVWAVGCIMA 191
>At4g26070 [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K)
Length = 354
Score = 85.5 bits (210), Expect = 3e-16
Identities = 58/207 (28%), Positives = 106/207 (51%), Gaps = 12/207 (5%)
Query: 429 LGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLRHPNIIST 488
+G G+ G+V+L+K Q FA+K + E + R I+ E I + + P ++S
Sbjct: 74 IGKGSSGNVQLVKHKLTQQFFALKVIQLNTEESTCR----AISQELRINLSSQCPYLVSC 129
Query: 489 IEIVYENNRIFQVMEYCDYDLFAIVMSN--KMSYEEICCCFKQILTGVEYLH-SIGLAHR 545
+ Y N + ++E+ D A ++ K+ + K++L G+ Y+H + HR
Sbjct: 130 YQSFYHNGLVSIILEFMDGGSLADLLKKVGKVPENMLSAICKRVLRGLCYIHHERRIIHR 189
Query: 546 DMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFTKYDPR 605
D+K N +IN++G VK+ DFG +++ + T ++ VG+ PY++PE + Y +
Sbjct: 190 DLKPSNLLINHRGEVKITDFGVSKIL----TSTSSLANSFVGTYPYMSPERISGSLYSNK 245
Query: 606 PVDIWSVAILFACMVLKKFPWKIPKLK 632
DIWS+ ++ KFP+ P+ K
Sbjct: 246 S-DIWSLGLVLLECATGKFPYTPPEHK 271
>At1g54610 [D] KOG0600 Cdc2-related protein kinase
Length = 572
Score = 85.5 bits (210), Expect = 3e-16
Identities = 57/196 (29%), Positives = 100/196 (50%), Gaps = 12/196 (6%)
Query: 427 ENLGAGAGGSVRLMKRISDNQVFAVKEFR-PKFEHESKRDYVKKITSEYCIGTTLRHPNI 485
+ +G G +V K + ++ A+K+ R E ES VK + E + L HPN+
Sbjct: 122 DKIGQGTYSNVYKAKDMLTGKIVALKKVRFDNLEPES----VKFMAREILVLRRLDHPNV 177
Query: 486 ISTIEIVYENNR--IFQVMEYCDYDLFAIVMSN--KMSYEEICCCFKQILTGVEYLHSIG 541
+ +V ++ V +Y D+DL + S K S E+ C +Q+++G+E+ HS G
Sbjct: 178 VKLEGLVTSRMSCSLYLVFQYMDHDLAGLASSPVVKFSESEVKCLMRQLISGLEHCHSRG 237
Query: 542 LAHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFTK 601
+ HRD+K N +I++ G++K+ DFG A +F H + + + V + Y APE+ +
Sbjct: 238 VLHRDIKGSNLLIDDGGVLKIADFGLATIFDPNHKRPM---TSRVVTLWYRAPELLLGAT 294
Query: 602 YDPRPVDIWSVAILFA 617
+D+WS + A
Sbjct: 295 DYGVGIDLWSAGCILA 310
>YKL101w [D] KOG0588 Serine/threonine protein kinase
Length = 1518
Score = 85.1 bits (209), Expect = 4e-16
Identities = 68/245 (27%), Positives = 109/245 (43%), Gaps = 41/245 (16%)
Query: 424 KTGENLGAGAGGSVRLMKRISDNQVFAVKEFRPK--FEHESKRDYVKK------------ 469
K G+ LG G+ G VRL K + Q+ A+K K F H S V
Sbjct: 82 KLGKTLGKGSSGRVRLAKNMETGQLAAIKIVPKKKAFVHCSNNGTVPNSYSSSMVTSNVS 141
Query: 470 -------------------ITSEYCIGTTLRHPNIISTIEIVYENNRIFQVMEYCDY-DL 509
I E I + H N+++ E+ + ++ V+EY D +L
Sbjct: 142 SPSIASREHSNHSQTNPYGIEREIVIMKLISHTNVMALFEVWENKSELYLVLEYVDGGEL 201
Query: 510 FAIVMSN-KMSYEEICCCFKQILTGVEYLHSIGLAHRDMKLDNCVINNQG-IVKLIDFGA 567
F ++S K+ E FKQI+ GV Y HS + HRD+K +N +++ + +K+ DFG
Sbjct: 202 FDYLVSKGKLPEREAIHYFKQIVEGVSYCHSFNICHRDLKPENLLLDKKNRRIKIADFGM 261
Query: 568 AEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFTKYDPRPVDIWSVAILFACMVLKKFPWK 627
A P+ L+++S GS Y +PE+ + Y P D+WS I+ ++ P+
Sbjct: 262 A-ALELPNK--LLKTS--CGSPHYASPEIVMGRPYHGGPSDVWSCGIVLFALLTGHLPFN 316
Query: 628 IPKLK 632
+K
Sbjct: 317 DDNIK 321
>Hs4502743 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 346
Score = 85.1 bits (209), Expect = 4e-16
Identities = 59/206 (28%), Positives = 101/206 (48%), Gaps = 7/206 (3%)
Query: 419 SKRYLKTGENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGT 478
+KRY K + LG G +V + + NQ+ A+K+ + E+K + E +
Sbjct: 9 AKRYEKL-DFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQ 67
Query: 479 TLRHPNIISTIEIVYENNRIFQVMEYCDYDLFAIVMSNKM--SYEEICCCFKQILTGVEY 536
L HPNII ++ + I V ++ + DL I+ N + + I L G+EY
Sbjct: 68 ELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEY 127
Query: 537 LHSIGLAHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEV 596
LH + HRD+K +N +++ G++KL DFG A+ F P+ + V + Y APE+
Sbjct: 128 LHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQ----VVTRWYRAPEL 183
Query: 597 CIFTKYDPRPVDIWSVAILFACMVLK 622
+ VD+W+V + A ++L+
Sbjct: 184 LFGARMYGVGVDMWAVGCILAELLLR 209
>Hs20547806 [R] KOG0589 Serine/threonine protein kinase
Length = 489
Score = 85.1 bits (209), Expect = 4e-16
Identities = 65/218 (29%), Positives = 104/218 (46%), Gaps = 14/218 (6%)
Query: 429 LGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLRHPNIIST 488
+G G+ G L++ S NQ+FA+KE R + ++ K E + ++HPNI++
Sbjct: 10 IGEGSFGRALLVQHESSNQMFAMKEIRLPKSFSNTQNSRK----EAVLLAKMKHPNIVAF 65
Query: 489 IEIVYENNRIFQVMEYCDY-DLFAIVMSNK---MSYEEICCCFKQILTGVEYLHSIGLAH 544
E ++ VMEYCD DL + K + I F Q+ GV ++H + H
Sbjct: 66 KESFEAEGHLYIVMEYCDGGDLMQKIKQQKGKLFPEDMILNWFTQMCLGVNHIHKKRVLH 125
Query: 545 RDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFTKYDP 604
RD+K N + G VKL DFG+A + S P + + VG+ Y+ PE+ Y+
Sbjct: 126 RDIKSKNIFLTQNGKVKLGDFGSARLLSNP----MAFACTYVGTPYYVPPEIWENLPYNN 181
Query: 605 RPVDIWSVAILFACMVLKKFPWKIPKLKDNSFKFFCSG 642
+ DIWS+ + + K P++ K+ K C G
Sbjct: 182 KS-DIWSLGCILYELCTLKHPFQANSWKNLILK-VCQG 217
>CE28218 [D] KOG0588 Serine/threonine protein kinase
Length = 914
Score = 85.1 bits (209), Expect = 4e-16
Identities = 75/339 (22%), Positives = 140/339 (41%), Gaps = 72/339 (21%)
Query: 424 KTGENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLRHP 483
K + LG G G V+ + A+K + ES ++K+ E I + HP
Sbjct: 48 KLEKTLGKGQTGLVKTGTHCITGRKVAIKIVNKEKLSES---VLQKVEREIAIMKLIEHP 104
Query: 484 NIISTIEIVYENNRIFQVM-------EYCDYDLFAIVMSNKMSYEEICCCFKQILTGVEY 536
+++ + VYEN + ++ E DY +V ++ +E F+QI++ +++
Sbjct: 105 HVLHLYD-VYENKKYLYLLLEHVSGGELFDY----LVRKGRLMSKEARKFFRQIISALDF 159
Query: 537 LHSIGLAHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEV 596
H+ + HRD+K +N +++ + +K+ DFG A S +++E+S GS Y PEV
Sbjct: 160 CHAHNICHRDLKPENLLLDERNNIKVADFGMA---SLQVEGSMLETS--CGSPHYACPEV 214
Query: 597 CIFTKYDPRPVDIWSVAILFACMVLKKFPWKIPKLKDNSFKFFCSGRDCDSLSALVTKTP 656
KYD R D+WS ++ +++ P+ D D+L L+ K
Sbjct: 215 IRGEKYDGRKADVWSCGVILYALLVGALPF-----------------DDDNLRNLLEKVK 257
Query: 657 KPPSYDNAVQSDEPAESTSKSNNPSDPNNTNIGPQRLLHSLPEETHHIIGRMVDLAPACR 716
+ G + H +P + ++ M+++ P R
Sbjct: 258 R-------------------------------GVFHIPHFVPADVQSLLRAMIEVDPGKR 286
Query: 717 ANIEEVLNDPWIQSIDMCTVEVDNQGNYVVH----PGMD 751
++ +V PW+ E++ + VV PG D
Sbjct: 287 YSLADVFKHPWVSGTTKADPELELPMSQVVQTHVIPGED 325
>CE06762 [T] KOG0660 Mitogen-activated protein kinase
Length = 367
Score = 85.1 bits (209), Expect = 4e-16
Identities = 66/216 (30%), Positives = 109/216 (49%), Gaps = 21/216 (9%)
Query: 427 ENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLRHPNII 486
EN+GAGA G V + + A+K+ F + K+ E I L H NII
Sbjct: 61 ENVGAGAYGVVCKAMDTRNKKQVAIKKIPRAF---TAHTLAKRSLREVRILRELLHENII 117
Query: 487 STIEIVYENNR----IFQVMEYCDYDLFAIVMSNKMSYEE-ICCCFKQILTGVEYLHSIG 541
+ +++ I+ VM+ + DL I+ S + E+ F Q+L G++YLHS G
Sbjct: 118 AVLDMFTAEGAHGKDIYLVMDLMETDLHQILHSRQTLMEQHFQYFFYQLLRGLKYLHSAG 177
Query: 542 LAHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGI-------VGSDPYLAP 594
+ HRD+K N ++N ++++ DFG A +Y + T+ + + + V + Y AP
Sbjct: 178 IIHRDLKPSNLLLNGDCLLRIADFGMAR--AYASASTVRDDANVGGHMTQYVSTRWYRAP 235
Query: 595 EVCI-FTKYDPRPVDIWSVAILFACMVLKK--FPWK 627
E+ +YD + VD+WS +FA M+L++ FP K
Sbjct: 236 EILFSMVEYDTK-VDLWSAGCIFAEMLLRRQLFPGK 270
>At2g30360 [T] KOG0583 Serine/threonine protein kinase
Length = 435
Score = 85.1 bits (209), Expect = 4e-16
Identities = 72/304 (23%), Positives = 123/304 (39%), Gaps = 53/304 (17%)
Query: 426 GENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLRHPNI 485
G+ LG GA V + Q AVK K + + I E I L HPNI
Sbjct: 24 GKLLGCGAFAKVFHARDRRTGQSVAVKILNKK-KLLTNPALANNIKREISIMRRLSHPNI 82
Query: 486 ISTIEIVYENNRIFQVMEYCDY-DLFAIVMSNKMSYEEICC-CFKQILTGVEYLHSIGLA 543
+ E++ ++IF ME+ +LF + + E++ F+Q+++ V Y H+ G+
Sbjct: 83 VKLHEVMATKSKIFFAMEFVKGGELFNKISKHGRLSEDLSRRYFQQLISAVGYCHARGVY 142
Query: 544 HRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFTKYD 603
HRD+K +N +I+ G +K+ DFG + + L+ + + G+ Y+APE+ Y+
Sbjct: 143 HRDLKPENLLIDENGNLKVSDFGLSALTDQIRPDGLLHT--LCGTPAYVAPEILSKKGYE 200
Query: 604 PRPVDIWSVAILFACMVLKKFPWKIPKLKDNSFKFFCSGRDCDSLSALVTKTPKPPSYDN 663
VD+WS I+ +V P+ P + + K +
Sbjct: 201 GAKVDVWSCGIVLFVLVAGYLPFNDPNVMNMYKKIY------------------------ 236
Query: 664 AVQSDEPAESTSKSNNPSDPNNTNIGPQRLLHSLPEETHHIIGRMVDLAPACRANIEEVL 723
G R + + + R++D+ P R I+E+L
Sbjct: 237 ------------------------KGEYRFPRWMSPDLKRFVSRLLDINPETRITIDEIL 272
Query: 724 NDPW 727
DPW
Sbjct: 273 KDPW 276
>7296451 [D] KOG0600 Cdc2-related protein kinase
Length = 1157
Score = 85.1 bits (209), Expect = 4e-16
Identities = 80/319 (25%), Positives = 136/319 (42%), Gaps = 41/319 (12%)
Query: 429 LGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLRHPNIIST 488
+G G G V + N + A+K+ R EHE K + E I L H NI++
Sbjct: 810 IGEGTYGQVYKARDHHTNDMVALKKVR--LEHE-KEGFPITAVREIKILRQLNHRNIVNL 866
Query: 489 IEIVYENN----------RIFQVMEYCDYDLFAIVMSNKMSYEEI--CCCFKQILTGVEY 536
EIV + + V EY D+DL ++ S + + E KQ+L G+ Y
Sbjct: 867 HEIVTDKQDAVEFRKDKGSFYLVFEYMDHDLMGLLESGMVDFNEENNASIMKQLLDGLNY 926
Query: 537 LHSIGLAHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEV 596
H HRD+K N ++NN+G VKL DFG A +++ + + I + Y PE+
Sbjct: 927 CHKKNFLHRDIKCSNILMNNRGKVKLADFGLARLYNADDRERPYTNKVI--TLWYRPPEL 984
Query: 597 CIFTKYDPRPVDIWSVAILFACMVLKKFPWKIPKLKDNSFKFFCSGRDCDSLSALVTKTP 656
+ + +D+WS + + +K+ P + N+ +++S + +P
Sbjct: 985 LLGEERYGPSIDVWSCGCILGELFVKR-----PLFQANA-----EMAQLETISK-ICGSP 1033
Query: 657 KPPSYDNAVQSDEPAESTSKSNNPSDPNNTNIGPQRL---LHSLPEETHHIIGRMVDLAP 713
P + N ++ P T K +RL +P ++ +M+DL P
Sbjct: 1034 VPAVWPNVIKL--PLFHTLKQKKTH--------RRRLREDFEFMPAPALDLLDKMLDLDP 1083
Query: 714 ACRANIEEVLNDPWIQSID 732
R E+ L PW++ I+
Sbjct: 1084 DKRITAEDALRSPWLRKIN 1102
>7291442 [D] KOG0669 Cyclin T-dependent kinase CDK9
Length = 404
Score = 85.1 bits (209), Expect = 4e-16
Identities = 61/211 (28%), Positives = 98/211 (45%), Gaps = 13/211 (6%)
Query: 419 SKRYLKTGENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGT 478
S +Y K + +G G G V + N+ F + K + E I
Sbjct: 47 SNKYEKVAK-IGQGTFGEVFKAREKKGNKKFVA--MKKVLMDNEKEGFPITALREIRILQ 103
Query: 479 TLRHPNIISTIEIVYEN--------NRIFQVMEYCDYDLFAIV--MSNKMSYEEICCCFK 528
L+H N+++ IEI + + V ++C++DL ++ M+ K S EI +
Sbjct: 104 LLKHENVVNLIEICRTKATATNGYRSTFYLVFDFCEHDLAGLLSNMNVKFSLGEIKKVMQ 163
Query: 529 QILTGVEYLHSIGLAHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGS 588
Q+L G+ Y+HS + HRDMK N +I GI+KL DFG A FS P +++ + V +
Sbjct: 164 QLLNGLYYIHSNKILHRDMKAANVLITKHGILKLADFGLARAFSIPKNESKNRYTNRVVT 223
Query: 589 DPYLAPEVCIFTKYDPRPVDIWSVAILFACM 619
Y PE+ + + PVD+W + A M
Sbjct: 224 LWYRPPELLLGDRNYGPPVDMWGAGCIMAEM 254
>YLR096w [T] KOG0583 Serine/threonine protein kinase
Length = 1147
Score = 84.7 bits (208), Expect = 5e-16
Identities = 60/228 (26%), Positives = 100/228 (43%), Gaps = 35/228 (15%)
Query: 427 ENLGAGAGGSVRLMKRISDNQVFAVK--------------------------EFRPKFEH 460
E +GAG+ G V+L+K ++ +K E + + E
Sbjct: 103 ETVGAGSMGKVKLVKHRQTKEICVIKIVNRASKAYLHKQHSLPSPKNESEILERQKRLEK 162
Query: 461 ESKRDYVKKITSEYCIGTTLRHPNIISTIEIVYENNRIFQVMEYCDYD--LFAIVMSNKM 518
E RD K+ E +G L HP+I E+ +N + + EY L I+ +
Sbjct: 163 EIARD--KRTVREASLGQILYHPHICRLFEMCTMSNHFYMLFEYVSGGQLLDYIIQHGSL 220
Query: 519 SYEEICCCFKQILTGVEYLHSIGLAHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKT 578
+ I + ++YLH+ + HRD+K++N +I++ G +K+IDFG + +F Y
Sbjct: 221 KEHHARKFARGIASALQYLHANNIVHRDLKIENIMISSSGEIKIIDFGLSNIFDYRK--- 277
Query: 579 LIESSGIVGSDPYLAPEVCIFTKYDPRPVDIWSVAILFACMVLKKFPW 626
+ GS + APE+ Y VDIWS I+ +V K P+
Sbjct: 278 --QLHTFCGSLYFAAPELLKAQPYTGPEVDIWSFGIVLYVLVCGKVPF 323
>Hs18552621 [R] KOG0597 Serine-threonine protein kinase FUSED
Length = 1315
Score = 84.7 bits (208), Expect = 5e-16
Identities = 60/190 (31%), Positives = 99/190 (51%), Gaps = 9/190 (4%)
Query: 427 ENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLRHPNII 486
E +G G+ G V +R QV A+K F PK K ++ + E I LRHPNI+
Sbjct: 8 EMIGEGSFGRVYKGRRKYSAQVVALK-FIPKLGRSEKE--LRNLQREIEIMRGLRHPNIV 64
Query: 487 STIEIVYENNRIFQVMEYCDYDLFAIVMSN-KMSYEEICCCFKQILTGVEYLHSIGLAHR 545
++ + + V +Y + +LF I+ + K+ +++ Q+++ + YLHS + HR
Sbjct: 65 HMLDSFETDKEVVVVTDYAEGELFQILEDDGKLPEDQVQAIAAQLVSALYYLHSHRILHR 124
Query: 546 DMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFTKYDPR 605
DMK N ++ G +KL DFG A S + T++ +S I G+ Y++PE+ YD
Sbjct: 125 DMKPQNILLAKGGGIKLCDFGFARAMS---TNTMVLTS-IKGTPLYMSPELVEERPYD-H 179
Query: 606 PVDIWSVAIL 615
D+WSV +
Sbjct: 180 TADLWSVGCI 189
>ECU08g1920 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 296
Score = 84.7 bits (208), Expect = 5e-16
Identities = 60/202 (29%), Positives = 99/202 (48%), Gaps = 12/202 (5%)
Query: 427 ENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLRHPNII 486
E +G G G V + + N+V A+K+ R + E+E E + L+H I+
Sbjct: 9 EKIGEGTYGVVYKARERNTNRVVALKKIRLENENEG---IPATTIREILLLKNLKHSTIV 65
Query: 487 STIEIVYENNRIFQVMEYCDYDLFAIV--MSNKMSYEE---ICCCFKQILTGVEYLHSIG 541
+++Y NN+++ V EY + DL + MS++ E + +Q+LT +EY HS
Sbjct: 66 ELSDVIYNNNKMYLVFEYVELDLRRYLDRMSDEGRLVEEGFVRKMSQQLLTAMEYCHSRN 125
Query: 542 LAHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFTK 601
+ HRD+K N +++ + +KL DFG P E V + Y PE+ + K
Sbjct: 126 IFHRDLKPQNILVDPKENIKLADFGLGRAAGIPLRTYTTE----VVTLWYRPPELLLGCK 181
Query: 602 YDPRPVDIWSVAILFACMVLKK 623
Y VD+WS A + A +VL +
Sbjct: 182 YYDASVDVWSAACIMAEVVLMR 203
>At3g48750 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 294
Score = 84.7 bits (208), Expect = 5e-16
Identities = 67/217 (30%), Positives = 100/217 (45%), Gaps = 11/217 (5%)
Query: 427 ENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLRHPNII 486
E +G G G V + N+ A+K+ R + E E + E + ++H NI+
Sbjct: 8 EKIGEGTYGVVYKARDKVTNETIALKKIRLEQEDEGVPSTAIR---EISLLKEMQHSNIV 64
Query: 487 STIEIVYENNRIFQVMEYCDYDLFAIVMSN---KMSYEEICCCFKQILTGVEYLHSIGLA 543
++V+ R++ V EY D DL + S I QIL G+ Y HS +
Sbjct: 65 KYDDVVHSEKRLYLVFEYLDLDLKKHMDSTPDFSKDLHMIKTYLYQILRGIAYCHSHRVL 124
Query: 544 HRDMKLDNCVINNQ-GIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFTKY 602
HRD+K N +I+ + +KL DFG A F P E V + Y APE+ + + +
Sbjct: 125 HRDLKPQNLLIDRRTNSLKLADFGLARAFGIPVRTFTHE----VVTLWYRAPEILLGSHH 180
Query: 603 DPRPVDIWSVAILFACMVLKKFPWKIPKLKDNSFKFF 639
PVDIWSV +FA M+ +K + D FK F
Sbjct: 181 YSTPVDIWSVGCIFAEMISQKPLFPGDSEIDQLFKIF 217
>7300149 [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 569
Score = 84.7 bits (208), Expect = 5e-16
Identities = 63/211 (29%), Positives = 109/211 (50%), Gaps = 17/211 (8%)
Query: 420 KRYLKTGENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTT 479
+RY KT + +G GA G V + + + AVK K ++S +D I +E +
Sbjct: 291 ERY-KTTQEVGKGASGIVFIAADLQNESQVAVKTIDMK--NQSSKDL---ILTEIRVLKD 344
Query: 480 LRHPNIISTIE--IVYENNRIFQVMEYCDYD-LFAIVMSNKMSYEEICCCFKQILTGVEY 536
H N+++ ++ ++ ++++ VMEY D L +V M +I C ++ L + +
Sbjct: 345 FNHKNLVNFLDAYLLEPEDQLWVVMEYMDGGPLTDVVTETVMKERQIACVCRETLYAISF 404
Query: 537 LHSIGLAHRDMKLDNCVINNQGIVKLIDFG-AAEVFSYPHSKTLIESSGIVGSDPYLAPE 595
LH+ G+ HRD+K DN ++ G VK+ DFG A + +T+ VG+ ++APE
Sbjct: 405 LHAKGIIHRDIKSDNVLLGMDGSVKVTDFGFCANIEGDEKRQTM------VGTPYWMAPE 458
Query: 596 VCIFTKYDPRPVDIWSVAILFACMVLKKFPW 626
V KY + VDIWS+ I+ M+ + P+
Sbjct: 459 VVTRKKYG-KKVDIWSIGIMAIEMIEGQPPY 488
>7297009 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 392
Score = 84.7 bits (208), Expect = 5e-16
Identities = 65/209 (31%), Positives = 95/209 (45%), Gaps = 13/209 (6%)
Query: 421 RYLKTGENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTL 480
RY K LG G+ G V + + AVK F E E K E + L
Sbjct: 3 RYEKLSR-LGEGSYGVVYKCRDRETGALVAVKRF---VESEDDPAIRKIALREIRLLKNL 58
Query: 481 RHPNIISTIEIVYENNRIFQVMEYCDYDLFAIVMSNKMSYEEICC---CFKQILTGVEYL 537
+HPN++S +E+ R+ V E+C+ + + + E C+ Q L GV Y
Sbjct: 59 KHPNLVSLLEVFRRKRRLHLVFEFCELTVLHELERHPQGCPEHLTKQICY-QTLLGVAYC 117
Query: 538 HSIGLAHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVC 597
H G HRD+K +N ++ QG VKL DFG A + S + T V + Y APE+
Sbjct: 118 HKQGCLHRDIKPENILLTAQGQVKLCDFGFARMLSPGENYT-----DYVATRWYRAPELL 172
Query: 598 IFTKYDPRPVDIWSVAILFACMVLKKFPW 626
+ PVD+W++ LFA +V + W
Sbjct: 173 VGDTQYGTPVDVWAIGCLFAELVRGEALW 201
>Hs4506085 [T] KOG0660 Mitogen-activated protein kinase
Length = 365
Score = 84.3 bits (207), Expect = 6e-16
Identities = 85/344 (24%), Positives = 150/344 (42%), Gaps = 38/344 (11%)
Query: 428 NLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLRHPNIIS 487
++G+GA GSV + A+K+ F+ E + K+ E + ++H N+I
Sbjct: 30 HVGSGAYGSVCSAIDKRSGEKVAIKKLSRPFQSEI---FAKRAYRELLLLKHMQHENVIG 86
Query: 488 TIEIVYENNRI------FQVMEYCDYDLFAIVMSNKMSYEEICCCFKQILTGVEYLHSIG 541
+++ + + + VM + DL I M + S E+I Q+L G++Y+HS G
Sbjct: 87 LLDVFTPASSLRNFYDFYLVMPFMQTDLQKI-MGMEFSEEKIQYLVYQMLKGLKYIHSAG 145
Query: 542 LAHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFTK 601
+ HRD+K N +N +K++DFG A H+ E +G V + Y APEV +
Sbjct: 146 VVHRDLKPGNLAVNEDCELKILDFGLAR-----HADA--EMTGYVVTRWYRAPEVILSWM 198
Query: 602 YDPRPVDIWSVAILFACMVLKKFPWKIPKLKDNSFKFFCSGRD-CDSLSALVTKTPKPPS 660
+ + VDIWSV + A M+ K +K G+D D L+ ++ T P +
Sbjct: 199 HYNQTVDIWSVGCIMAEMLTGKTLFK--------------GKDYLDQLTQILKVTGVPGT 244
Query: 661 YDNAVQSDEPAESTSKSNNPSDPNNTNIGPQRLLHSLPEETHHIIGRMVDLAPACRANIE 720
+D+ A KS S P +L + ++ +M++L R
Sbjct: 245 EFVQKLNDKAA----KSYIQSLPQTPRKDFTQLFPRASPQAADLLEKMLELDVDKRLTAA 300
Query: 721 EVLNDPWIQSIDMCTVEVDNQGNYVVHPGMDHKHTQVDQSEAHI 764
+ L P+ + E + + ++H+ VD+ + HI
Sbjct: 301 QALTHPFFEPFR--DPEEETEAQQPFDDSLEHEKLTVDEWKQHI 342
>CE27670 [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 572
Score = 84.3 bits (207), Expect = 6e-16
Identities = 65/210 (30%), Positives = 105/210 (49%), Gaps = 16/210 (7%)
Query: 420 KRYLKTGENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKK--ITSEYCIG 477
++Y K + +G+GA GSV IS A+K+ K D KK I +E +
Sbjct: 293 RKYRKV-DKIGSGASGSVYTAIEISTEAEVAIKQMNLK-------DQPKKELIINEILVM 344
Query: 478 TTLRHPNIISTIEIVYENNRIFQVMEY-CDYDLFAIVMSNKMSYEEICCCFKQILTGVEY 536
+H NI++ ++ + ++ VMEY L +V +M I +++L +E+
Sbjct: 345 RENKHANIVNYLDSYLVCDELWVVMEYLAGGSLTDVVTECQMEDGIIAAVCREVLQALEF 404
Query: 537 LHSIGLAHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEV 596
LHS + HRD+K DN ++ G VKL DFG S K + +VG+ ++APEV
Sbjct: 405 LHSRHVIHRDIKSDNILLGMDGSVKLTDFGFCAQLSPEQRK----RTTMVGTPYWMAPEV 460
Query: 597 CIFTKYDPRPVDIWSVAILFACMVLKKFPW 626
+Y P+ VD+WS+ I+ MV + P+
Sbjct: 461 VTRKQYGPK-VDVWSLGIMAIEMVEGEPPY 489
>CE17284 [T] KOG0583 Serine/threonine protein kinase
Length = 726
Score = 84.3 bits (207), Expect = 6e-16
Identities = 61/207 (29%), Positives = 98/207 (46%), Gaps = 15/207 (7%)
Query: 427 ENLGAGAGGSVRLMKRISDNQVFAVKEFRPK-FEHESKRDYVKKITSEYCIGTTLRHPNI 485
+ LG+G G VRL + NQ A+K K H+ R + +E L H NI
Sbjct: 15 DELGSGGFGKVRLATHLLTNQKVAIKIIDKKQLGHDLPR-----VQTEMDALRNLSHQNI 69
Query: 486 ISTIEIVYENNRIFQVMEYCDY-DLFA-IVMSNKMSYEEICCCFKQILTGVEYLHSIGLA 543
+ ++ F VMEYC ++F IV ++ E F+Q+++ + ++HS G A
Sbjct: 70 CRLYHYIETEDKFFIVMEYCSGGEMFDYIVRKERLEESEARHFFRQLVSAIAFVHSQGYA 129
Query: 544 HRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGI---VGSDPYLAPEVCIFT 600
HRD+K +N ++ +KLIDFG K I+ + GS Y APE+
Sbjct: 130 HRDLKPENLLLTEDLHLKLIDFGLCA----KTEKGRIDKHNLDTCCGSPAYAAPELIQGL 185
Query: 601 KYDPRPVDIWSVAILFACMVLKKFPWK 627
+Y D+WS+ IL +++ P++
Sbjct: 186 QYKGNEADVWSMGILLYTLLVGALPFE 212
>CE00315 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 332
Score = 84.3 bits (207), Expect = 6e-16
Identities = 76/318 (23%), Positives = 133/318 (40%), Gaps = 23/318 (7%)
Query: 427 ENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLRHPNII 486
E +G G G V K N + A+K+ R + E E + E + L+HPN++
Sbjct: 26 EKIGEGTYGVVYKGKNRRTNAMVAMKKIRLESEDEGVPSTAVR---EISLLKELQHPNVV 82
Query: 487 STIEIVYENNRIFQVMEYCDYDLFAIV----MSNKMSYEEICCCFKQILTGVEYLHSIGL 542
++ + NR+F + E+ +DL + + E + QIL + + H +
Sbjct: 83 GLEAVIMQENRLFLIFEFLSFDLKRYMDQLGKDEYLPLETLKSYTFQILQAMCFCHQRRV 142
Query: 543 AHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFTKY 602
HRD+K N +++N G +KL DFG A P E V + Y APE+ + +
Sbjct: 143 IHRDLKPQNLLVDNNGAIKLADFGLARAIGIPIRVYTHE----VVTLWYRAPEILMGAQR 198
Query: 603 DPRPVDIWSVAILFACMVLKKFPWKIPKLKDNSFKFFCSGRDCDSLSALVTKTPKPPSYD 662
VD+WS+ +FA M KK ++ D F+ F V TP +
Sbjct: 199 YSMGVDMWSIGCIFAEMATKKPLFQGDSEIDELFRIF-----------RVLGTPTELEW- 246
Query: 663 NAVQSDEPAESTSKSNNPSDPNNTNIGPQRLLHSLPEETHHIIGRMVDLAPACRANIEEV 722
N V+S ++T + + + H L + ++ ++ P+ R N ++
Sbjct: 247 NGVESLPDYKATFPKWRENFLRDKFYDKKTGKHLLDDTAFSLLEGLLIYDPSLRLNAKKA 306
Query: 723 LNDPWIQSIDMCTVEVDN 740
L P+ ++D + N
Sbjct: 307 LVHPYFDNMDTSKLPAGN 324
>YJL095w [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 1478
Score = 84.0 bits (206), Expect = 8e-16
Identities = 63/208 (30%), Positives = 103/208 (49%), Gaps = 12/208 (5%)
Query: 426 GENLGAGAGGSVRLMKRISDNQVFAVKEFR-PKF--EHESKRDYVKKITSEYCIGTTLRH 482
GE +G G+ G+V L ++ ++ AVK+ PK+ ++E+ V+ + SE L H
Sbjct: 1178 GEMIGKGSFGAVYLCLNVTTGEMMAVKQVEVPKYSSQNEAILSTVEALRSEVSTLKDLDH 1237
Query: 483 PNIISTIEIVYENNRIFQVMEYCDYDLFAIVMSNKMSYEE--ICCCFKQILTGVEYLHSI 540
NI+ + +NN +EY ++ ++E I Q+L G+ YLHS
Sbjct: 1238 LNIVQYLGFENKNNIYSLFLEYVAGGSVGSLIRMYGRFDEPLIKHLTTQVLKGLAYLHSK 1297
Query: 541 GLAHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIV--GSDPYLAPEVCI 598
G+ HRDMK DN +++ GI K+ DFG + SK + +S + G+ ++APE+
Sbjct: 1298 GILHRDMKADNLLLDQDGICKISDFGISR-----KSKDIYSNSDMTMRGTVFWMAPEMVD 1352
Query: 599 FTKYDPRPVDIWSVAILFACMVLKKFPW 626
+ VDIWS+ + M K PW
Sbjct: 1353 TKQGYSAKVDIWSLGCIVLEMFAGKRPW 1380
>CE27220 [T] KOG0660 Mitogen-activated protein kinase
Length = 472
Score = 84.0 bits (206), Expect = 8e-16
Identities = 64/208 (30%), Positives = 98/208 (46%), Gaps = 16/208 (7%)
Query: 427 ENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKIT-SEYCIGTTLRHPNI 485
+N+G+GA G V S NQ A+K K H S + + T E + + HPNI
Sbjct: 86 QNIGSGAFGIVCEAVETSSNQKVAIK----KVAHASATPTLARRTLREIRVLRYINHPNI 141
Query: 486 ISTIEIVYENNR----IFQVMEYCDYDLFAIVMSNKMSYEE--ICCCFKQILTGVEYLHS 539
+ +I +F VM+ +L I+ N+ EE I Q+L G+EYLH+
Sbjct: 142 VPLRDIFRTKGPLGIDVFLVMDLMQNNLHHIIYGNEDPLEEHYINAFLGQLLRGLEYLHA 201
Query: 540 IGLAHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIES-----SGIVGSDPYLAP 594
+AHRD+K N ++N G +++ DFG A+ K E + V + PY AP
Sbjct: 202 ACIAHRDLKPSNLLVNQDGTLRIADFGMAKCADNSSKKHDDEEHCYYMTQHVATLPYRAP 261
Query: 595 EVCIFTKYDPRPVDIWSVAILFACMVLK 622
E+ VD+W+V +F MV++
Sbjct: 262 ELLFVLPEHSTAVDMWAVGCIFGEMVIR 289
>CE23001 [R] KOG0589 Serine/threonine protein kinase
Length = 579
Score = 84.0 bits (206), Expect = 8e-16
Identities = 63/225 (28%), Positives = 110/225 (48%), Gaps = 13/225 (5%)
Query: 404 NDVVYAASHVPALPFSKRYLKTGENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESK 463
N+++ + A RY + +G GA GS L +R D+ + +KE S+
Sbjct: 153 NEIMITNPNPRATSAQNRYERI-RTVGKGAFGSAVLYRRREDSSLVIIKEINMYDLDSSQ 211
Query: 464 RDYVKKITSEYCIGTTLRHPNIISTIEIVYENNRIFQVMEYCDYDLFAIVMS---NKMSY 520
R + +E + + + HPNII+ + E + MEY D A ++S N +
Sbjct: 212 R---RLALNEVSLLSRIEHPNIIAYYDSFEEEGVLMIEMEYADGGTLAQMLSRTQNLLDE 268
Query: 521 EEICCCFKQILTGVEYLHSIGLAHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLI 580
E+I Q+ + V YLH + HRD+K N + VK+ DFG +++ ++TL
Sbjct: 269 EQIGDMMIQMCSAVAYLHENSVLHRDLKTANVFLTRDSFVKIGDFGISKIMG---TETLA 325
Query: 581 E-SSGIVGSDPYLAPEVCIFTKYDPRPVDIWSV-AILFACMVLKK 623
+ + +VG+ Y++PE+C Y+ + D+W++ IL+ LKK
Sbjct: 326 QGAKTVVGTPYYISPEMCSGVSYNEKS-DMWALGCILYEMCCLKK 369
>At3g45240 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kinase beta
and related serine/threonine protein kinases
Length = 382
Score = 84.0 bits (206), Expect = 8e-16
Identities = 61/218 (27%), Positives = 104/218 (46%), Gaps = 25/218 (11%)
Query: 429 LGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLR------- 481
+G+G+ G V L + D++ +A+K F H+S ++ SE +G LR
Sbjct: 103 IGSGSYGKVVLYRSTVDDKHYAIKAF-----HKSHLSRLRVAPSETAMGDVLREVMIMKT 157
Query: 482 --HPNIISTIEIVY--ENNRIFQVMEYCDYDLFAIVMSNKMSYEEICC--CFKQILTGVE 535
HPNI++ IE++ E + + V+EY D + EI + ++ G+
Sbjct: 158 LEHPNIVNLIEVIDDPEFDDFYMVLEYVDGKWAYDDSGPPGALGEITARKYLRDVVAGLM 217
Query: 536 YLHSIGLAHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPE 595
YLH+ + H D+K DN ++ + G VK+ DF ++ L S G + + APE
Sbjct: 218 YLHAHNVIHGDIKPDNLLVTSTGRVKIGDFSVSQ----DDDDQLRRSPG---TPVFTAPE 270
Query: 596 VCIFTKYDPRPVDIWSVAILFACMVLKKFPWKIPKLKD 633
C+ Y R D W+V + CM+L ++P+ L+D
Sbjct: 271 CCLGITYSGRSADTWAVGVTLYCMILGQYPFLGDTLQD 308
>At1g18040 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 391
Score = 84.0 bits (206), Expect = 8e-16
Identities = 83/314 (26%), Positives = 136/314 (42%), Gaps = 34/314 (10%)
Query: 421 RYLKTGENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTL 480
RYLK E LG G G V Q A+K+ R + E + E + L
Sbjct: 11 RYLKQ-EVLGQGTYGVVFKATDTKTEQTVAIKKIRLGKQREGVNITALR---EIKMLKEL 66
Query: 481 RHPNIISTIEIVYENNRIFQVMEYCDYDLFAIVMSNK--MSYEEICCCFKQILTGVEYLH 538
+HP+II I+ + V E+ + DL A++ + +S +I G+ Y H
Sbjct: 67 KHPHIILLIDAFPHKENLHLVFEFMETDLEAVIRDSNIFLSPADIKSYLLMTFKGLAYCH 126
Query: 539 SIGLAHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCI 598
+ HRDMK +N +I G +KL DFG A +F P+ K + V + Y APE+
Sbjct: 127 DKWVLHRDMKPNNLLIGVDGQLKLADFGLARIFGSPNRKFTHQ----VFARWYRAPELLF 182
Query: 599 FTKYDPRPVDIWSVAILFACMVLKKFPWKIPKLKDNSFKFFCSGRDCDSLSALVTK--TP 656
K VD+W+VA +FA ++L++ P L+ NS D D LS + TP
Sbjct: 183 GAKQYGAAVDVWAVACIFAELLLRR-----PFLQGNS--------DIDQLSKIFAAFGTP 229
Query: 657 KPPSYDNAVQSDEPAESTSKSNNPSDPNNTNIGPQRLLHSLPEETHHIIGRMVDLAPACR 716
K + + + + E P+ ++ P ++ ++ ++ +M P R
Sbjct: 230 KADQWPDLTKLPDYVE----YQFVPAPSLRSLFP-----AVSDDALDLLSKMFTYDPKAR 280
Query: 717 ANIEEVLNDPWIQS 730
+I++ L + S
Sbjct: 281 ISIKQALEHRYFTS 294
>7303804 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 387
Score = 84.0 bits (206), Expect = 8e-16
Identities = 77/304 (25%), Positives = 135/304 (44%), Gaps = 31/304 (10%)
Query: 429 LGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLRHPNIIST 488
+G G+ G V + N++ A+K+ R E K E I H NI+
Sbjct: 59 VGEGSYGIVYRARDTRSNEIVALKKVRMDQE---KDGLPISGLREIMILKQCHHENIVRL 115
Query: 489 IEIVYENN--RIFQVMEYCDYDLFAIV--MSNKMSYEEICCCFKQILTGVEYLHSIGLAH 544
E+V + IF VM++C+ DL +++ MS + E+ C Q+L ++YLHS + H
Sbjct: 116 REVVVGKSLDSIFLVMDFCEQDLASVLDNMSQPFTESEVKCITLQVLKALKYLHSRFMIH 175
Query: 545 RDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFTKYDP 604
RD+K+ N ++ ++G +K+ DFG A +FS P + + Y APE+ + +
Sbjct: 176 RDLKVSNLLMTDKGCIKVADFGLARMFSNPPKPMTPQMVTLW----YRAPELLLGCRTHT 231
Query: 605 RPVDIWSVAILFACMVLKKFPWKIPKLKDNSFKFFCSGRDCDSLSALVTKTPKPPSYDNA 664
VD+W+ + ++L K P L NS + L ++ P
Sbjct: 232 TAVDMWAFGCILGELLLGK-----PLLPGNS--------EIAQLDMIIDLLGAPSESIWP 278
Query: 665 VQSDEPA-ESTSKSNNPSDPNNTNIGPQRLLHSLPEETHHIIGRMVDLAPACRANIEEVL 723
+D PA ++ + S P + N+ P+ H + + +++ + P RA EE L
Sbjct: 279 GFADLPAVQNFTLSQQPYN----NLTPK--FHMIGQSGRNLLNILFIYNPKTRATAEECL 332
Query: 724 NDPW 727
+
Sbjct: 333 KSKY 336
>SPAC9G1.02 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and related
serine/threonine protein kinases
Length = 1401
Score = 83.6 bits (205), Expect = 1e-15
Identities = 56/210 (26%), Positives = 104/210 (48%), Gaps = 10/210 (4%)
Query: 426 GENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLRHPNI 485
G + +G G V + + AVKE + + + + R V +I +E + L HPN+
Sbjct: 1040 GHFVRSGMFGDVYTGVNMETGDLLAVKEIKLQ-DSRTFRSTVDQIHNEMTVLERLNHPNV 1098
Query: 486 ISTIEIVYENNRIFQVMEYCDYDLFAIVMSNKMSYEE--ICCCFKQILTGVEYLHSIGLA 543
++ + +++ ME+C A ++++ +E + Q+L G+ Y+HS +
Sbjct: 1099 VTYYGVEVHREKVYIFMEFCQGGSLADLLAHGRIEDENVLKVYVVQLLEGLAYIHSQHIL 1158
Query: 544 HRDMKLDNCVINNQGIVKLIDFGAAEVFSYP------HSKTLIESSGIVGSDPYLAPEVC 597
HRD+K N +++++G++K DFG+A S P + E + G+ Y+APE+
Sbjct: 1159 HRDIKPANILLDHRGMIKYSDFGSALYVSPPTDPEVRYEDIQPELQHLAGTPMYMAPEII 1218
Query: 598 IFTKY-DPRPVDIWSVAILFACMVLKKFPW 626
+ TK D +DIWS+ + M+ PW
Sbjct: 1219 LGTKKGDFGAMDIWSLGCVILEMMTGSTPW 1248
>ECU05g1510 [TDK] KOG0668 Casein kinase II alpha subunit
Length = 319
Score = 83.6 bits (205), Expect = 1e-15
Identities = 64/191 (33%), Positives = 104/191 (53%), Gaps = 10/191 (5%)
Query: 440 MKRISDNQVFAVKEFRPKFEHESKRDYVK-KITSEYCIGTTLRHPNIISTIEIVYE-NNR 497
M R ++VF ++ R K ++ + K KI E I L H NII +++V + ++
Sbjct: 43 MGRGKYSEVFEGRKDREKIVIKALKPVRKAKICREVLILRNLSHKNIIKLMDVVVDPESQ 102
Query: 498 IFQ-VMEYCDYDLFAIVMSNKMSYEEICCCFKQILTGVEYLHSIGLAHRDMKLDNCVINN 556
I+ + EY +++ +A + K+ Y++I +QIL+ + Y HS+G+ HRD+K N VIN
Sbjct: 103 IYSLIFEYIEHEDYAKIFE-KLCYKDIVEYSRQILSALSYCHSMGIIHRDIKPQNMVINQ 161
Query: 557 -QGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFTKYDPRPVDIWSVAIL 615
+ +K+ID+G AE + H K E S V S Y PE+ + Y +DIWS +
Sbjct: 162 ARRELKIIDWGLAEFY---HPKK--EYSVRVASRYYKGPELLVDYPYYDYSLDIWSFGCV 216
Query: 616 FACMVLKKFPW 626
A +V KK P+
Sbjct: 217 LAELVFKKRPF 227
>ECU03g0980 [T] KOG0583 Serine/threonine protein kinase
Length = 566
Score = 83.6 bits (205), Expect = 1e-15
Identities = 62/235 (26%), Positives = 110/235 (46%), Gaps = 25/235 (10%)
Query: 419 SKRYLKTGENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYV----KKITSEY 474
S R++K LG G+ V L + + + A+K + D +++ E
Sbjct: 57 SYRFVK---QLGTGSSSKVVLGRDVRSGEKVAIKIIPRRVNGGETGDMEMRCDQRVFREV 113
Query: 475 CIGTTLRHPNIISTIEIVYENNRIFQVMEYCD----YDLFAIVMSNKMSYEEICCCFKQI 530
I + L HP+I +Y F + EY YD+ I+ S + +E F+Q+
Sbjct: 114 IISSVLNHPHIARLKNFLYSPTHYFLIFEYVKGRQLYDI--IISSGPLKEKEGQRYFRQL 171
Query: 531 LTGVEYLHSIGLAHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDP 590
L+ ++Y+H + HRD+K++N +I+ VKLIDFG + + +KTL+ + GS
Sbjct: 172 LSAIDYIHRNSVVHRDLKIENILIDENDNVKLIDFGLSNFYD---NKTLLNT--FCGSLY 226
Query: 591 YLAPEVCIFTKYDPRPVDIWSVAILFACMVLKKFPWK-------IPKLKDNSFKF 638
+ APE+ +Y +D+WS+ ++ ++ P+ K+ D FKF
Sbjct: 227 FAAPELLQGQRYCGPEIDVWSLGVVLYAILCGCVPFDDEDVQGLQAKIMDADFKF 281
>At5g01820 [T] KOG0583 Serine/threonine protein kinase
Length = 442
Score = 83.6 bits (205), Expect = 1e-15
Identities = 57/193 (29%), Positives = 96/193 (49%), Gaps = 5/193 (2%)
Query: 424 KTGENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLRHP 483
+ G+ +G GA V + + Q A+K + K I E I LRHP
Sbjct: 23 EVGKLVGCGAFAKVYHGRSTATGQSVAIKVVSK--QRLQKGGLNGNIQREIAIMHRLRHP 80
Query: 484 NIISTIEIVYENNRIFQVMEYCDY-DLFAIVMSNKMSYEEICCCFKQILTGVEYLHSIGL 542
+I+ E++ ++IF VME+ +LFA V + + F+Q+++ V Y HS G+
Sbjct: 81 SIVRLFEVLATKSKIFFVMEFAKGGELFAKVSKGRFCEDLSRRYFQQLISAVGYCHSRGI 140
Query: 543 AHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFTKY 602
HRD+K +N +++ + +K+ DFG + + L+ + + G+ Y+APEV Y
Sbjct: 141 FHRDLKPENLLLDEKLDLKISDFGLSALTDQIRPDGLLHT--LCGTPAYVAPEVLAKKGY 198
Query: 603 DPRPVDIWSVAIL 615
D +DIWS I+
Sbjct: 199 DGAKIDIWSCGII 211
>At1g12680 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 470
Score = 83.6 bits (205), Expect = 1e-15
Identities = 62/205 (30%), Positives = 98/205 (47%), Gaps = 19/205 (9%)
Query: 426 GENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLRHPNI 485
G N+G G GSVR+ K + FA K + E + + + S HP +
Sbjct: 110 GRNIGKGKFGSVRICKSRKNGTEFACKTLKKGEETVHREVEIMQHLSG--------HPRV 161
Query: 486 ISTIEIVYENNRIFQ-VMEYCDYD--LFAIVMSNKMSYEEICCCFKQILTGVEYLHSIGL 542
+ T+ VYE + F VME C + +V + S + FK ++ + Y H +G+
Sbjct: 162 V-TLHAVYEESDCFHLVMELCSGGRLIDQMVKVGRYSEQRAANIFKDLMLVINYCHEMGV 220
Query: 543 AHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFTKY 602
HRD+K +N ++ G ++L DFG A +TL SG+ GS Y+APEV + Y
Sbjct: 221 VHRDIKPENILLTAAGKIQLADFGLA--MRIAKGQTL---SGLAGSPAYVAPEV-LSENY 274
Query: 603 DPRPVDIWSVAILFACMVLKKFPWK 627
+ VD+WS +L ++ P+K
Sbjct: 275 SEK-VDVWSAGVLLYALLSGVLPFK 298
>At1g03740 [D] KOG0600 Cdc2-related protein kinase
Length = 542
Score = 83.6 bits (205), Expect = 1e-15
Identities = 54/193 (27%), Positives = 101/193 (51%), Gaps = 10/193 (5%)
Query: 427 ENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLRHPNII 486
E +G G SV + + N++ A+K+ R + + VK + E + L HPN++
Sbjct: 217 EKIGQGTYSSVYRARDLLHNKIVALKKVRFDL---NDMESVKFMAREIIVMRRLDHPNVL 273
Query: 487 STIEIVYE--NNRIFQVMEYCDYDLFAI--VMSNKMSYEEICCCFKQILTGVEYLHSIGL 542
++ ++ ++ V EY D+DL + + K + ++ C +Q+L+G+E+ HS G+
Sbjct: 274 KLEGLITAPVSSSLYLVFEYMDHDLLGLSSLPGVKFTEPQVKCYMRQLLSGLEHCHSRGV 333
Query: 543 AHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFTKY 602
HRD+K N +I+++G++K+ DFG A F S +L + V + Y PE+ + +
Sbjct: 334 LHRDIKGSNLLIDSKGVLKIADFGLATFFDPAKSVSL---TSHVVTLWYRPPELLLGASH 390
Query: 603 DPRPVDIWSVAIL 615
VD+WS +
Sbjct: 391 YGVGVDLWSTGCI 403
>7294217 [D] KOG0588 Serine/threonine protein kinase
Length = 851
Score = 83.6 bits (205), Expect = 1e-15
Identities = 70/305 (22%), Positives = 135/305 (43%), Gaps = 60/305 (19%)
Query: 427 ENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLRHPNII 486
+ LG G G V+L + A+K + ES + K+ E I + HP+++
Sbjct: 22 KTLGKGQTGLVKLGVHCVIGKKVAIKIINREKLSES---VLMKVEREIAIMKLIDHPHVL 78
Query: 487 STIEIVYENNR-IFQVMEYCDY-DLFA-IVMSNKMSYEEICCCFKQILTGVEYLHSIGLA 543
+ VYEN + ++ ++E+ +LF +V +++ +E F+QI++ +++ HS +
Sbjct: 79 GLSD-VYENKKYLYLILEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSIC 137
Query: 544 HRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFTKYD 603
HRD+K +N +++ + +K+ DFG A S + +++E+S GS Y PEV KYD
Sbjct: 138 HRDLKPENLLLDEKNNIKIADFGMA---SLQPAGSMLETS--CGSPHYACPEVIRGEKYD 192
Query: 604 PRPVDIWSVAILFACMVLKKFPWKIPKLKDNSFKFFCSGRDCDSLSALVTKTPKPPSYDN 663
R D+WS ++ +++ P+ D D+L L+ K +
Sbjct: 193 GRKADVWSCGVILYALLVGALPF-----------------DDDNLRQLLEKVKR------ 229
Query: 664 AVQSDEPAESTSKSNNPSDPNNTNIGPQRLLHSLPEETHHIIGRMVDLAPACRANIEEVL 723
G + H +P + ++ M+++ P R + E+
Sbjct: 230 -------------------------GVFHIPHFVPPDCQSLLRGMIEVNPDRRLTLAEIN 264
Query: 724 NDPWI 728
PW+
Sbjct: 265 RHPWV 269
>Hs4826684_1 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 370
Score = 83.6 bits (205), Expect = 1e-15
Identities = 63/204 (30%), Positives = 104/204 (50%), Gaps = 19/204 (9%)
Query: 422 YLKTGENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKK-ITSEYCIGTTL 480
Y TGE LG+G V+ + S +A K + + S+R ++ I E I +
Sbjct: 12 YYDTGEELGSGQFAVVKKCREKSTGLQYAAKFIKKRRTKSSRRGVSREDIEREVSILKEI 71
Query: 481 RHPNIISTIEIVYENNR-IFQVMEY-CDYDLFAIVMSNKMSYEEICCCF-KQILTGVEYL 537
+HPN+I T+ VYEN + ++E +LF + + EE F KQIL GV YL
Sbjct: 72 QHPNVI-TLHEVYENKTDVILILELVAGGELFDFLAEKESLTEEEATEFLKQILNGVYYL 130
Query: 538 HSIGLAHRDMKLDNCVINNQGI----VKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLA 593
HS+ +AH D+K +N ++ ++ + +K+IDFG A + + E I G+ ++A
Sbjct: 131 HSLQIAHFDLKPENIMLLDRNVPKPRIKIIDFGLAHKIDFGN-----EFKNIFGTPEFVA 185
Query: 594 PEVCIFTKYDP--RPVDIWSVAIL 615
PE+ Y+P D+WS+ ++
Sbjct: 186 PEI---VNYEPLGLEADMWSIGVI 206
>YER129w [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kinase beta
and related serine/threonine protein kinases
Length = 1142
Score = 83.2 bits (204), Expect = 1e-15
Identities = 74/257 (28%), Positives = 119/257 (45%), Gaps = 47/257 (18%)
Query: 417 PFSKR-YLKTGE---NLGAGAGGSVRLMKRISDNQVFAVK-----EFRPK----FEHESK 463
P SKR L T E LG G G V+L + I Q+ A+K E + + F SK
Sbjct: 123 PVSKRKVLNTYEIIKELGHGQHGKVKLARDILSKQLVAIKIVDRHEKKQRKFFTFIKSSK 182
Query: 464 RDYVKKITSEYCIGTTLRHPNIISTIEIV--YENNRIFQVMEYCDYDLFAIVMSNKM--- 518
KI E I H +++ IE++ ++ +I+ V+EYC + M
Sbjct: 183 ISENDKIKREIAIMKKCHHKHVVQLIEVLDDLKSRKIYLVLEYCSRGEVKWCPPDCMESD 242
Query: 519 -------SYEEICCCFKQILTGVEYLHSIGLAHRDMKLDNCVINNQGIVKLIDFG----A 567
S++E + ++ G+EYLH G+ HRD+K N +I+ G VK+ DFG A
Sbjct: 243 AKGPSLLSFQETREILRGVVLGLEYLHYQGIIHRDIKPANLLISGDGTVKISDFGVSLAA 302
Query: 568 AEVFSYPHSKTL--IESSGIVGSDPYLAPEVCI----FTKYDPRP------------VDI 609
+ S S++L +E + VG+ + APE+C+ FT+Y+ +DI
Sbjct: 303 SSTNSSDSSESLDELELAKTVGTPAFFAPEMCLGEDAFTRYNLTKENLFRGSCISFMIDI 362
Query: 610 WSVAILFACMVLKKFPW 626
W+V + C++ P+
Sbjct: 363 WAVGVTLYCLLFGMLPF 379
>SPAC1F5.09c [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 589
Score = 83.2 bits (204), Expect = 1e-15
Identities = 58/207 (28%), Positives = 102/207 (49%), Gaps = 7/207 (3%)
Query: 422 YLKTGENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLR 481
Y LG GA GSV L K + Q+ K + + I +E +
Sbjct: 308 YFNVKHKLGQGASGSVYLAKVVGGKQLGIFDSVAIKSIDLQCQTRKELILNEITVMRESI 367
Query: 482 HPNIISTIE-IVYENNRIFQVMEYCDY-DLFAIVMSNKMSYEEICCCFKQILTGVEYLHS 539
HPNI++ ++ + ++ VMEY + L I+ +K++ +I + G+++LH+
Sbjct: 368 HPNIVTYLDSFLVRERHLWVVMEYMNAGSLTDIIEKSKLTEAQIARICLETCKGIQHLHA 427
Query: 540 IGLAHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIF 599
+ HRD+K DN +++N G +K+ DFG S +K + +VG+ ++APEV
Sbjct: 428 RNIIHRDIKSDNVLLDNSGNIKITDFGFCARLSNRTNKRVT----MVGTPYWMAPEVVKQ 483
Query: 600 TKYDPRPVDIWSVAILFACMVLKKFPW 626
+Y + VDIWS+ I+ M+ + P+
Sbjct: 484 NEYGTK-VDIWSLGIMIIEMIENEPPY 509
>Hs4502741 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 326
Score = 83.2 bits (204), Expect = 1e-15
Identities = 70/271 (25%), Positives = 117/271 (42%), Gaps = 37/271 (13%)
Query: 479 TLRHPNIIS-----TIEIVYENNRIFQVMEYCDYDLFAI---VMSNKMSYEEICCCFKQI 530
T HPN++ T+ ++ V E+ D DL V + E I Q+
Sbjct: 70 TFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTETIKDMMFQL 129
Query: 531 LTGVEYLHSIGLAHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDP 590
L G+++LHS + HRD+K N ++ + G +KL DFG A ++S+ + T +V +
Sbjct: 130 LRGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQMALT-----SVVVTLW 184
Query: 591 YLAPEVCIFTKYDPRPVDIWSVAILFACMVLKKFPWKIPKLKDNSFKFFCSGRDCDSLSA 650
Y APEV + + Y PVD+WSV +FA M +K F D D L
Sbjct: 185 YRAPEVLLQSSY-ATPVDLWSVGCIFAEMFRRK-------------PLFRGSSDVDQLGK 230
Query: 651 LVTKTPKPPSYDNAVQSDEPAES-TSKSNNPSDPNNTNIGPQRLLHSLPEETHHIIGRMV 709
++ P D P ++ SKS P ++ + + E ++ + +
Sbjct: 231 ILDVIGLPGEEDWPRDVALPRQAFHSKSAQPI---------EKFVTDIDELGKDLLLKCL 281
Query: 710 DLAPACRANIEEVLNDPWIQSIDMCTVEVDN 740
PA R + L+ P+ Q ++ C +D+
Sbjct: 282 TFNPAKRISAYSALSHPYFQDLERCKENLDS 312
>Hs16507245 [T] KOG0583 Serine/threonine protein kinase
Length = 358
Score = 83.2 bits (204), Expect = 1e-15
Identities = 63/207 (30%), Positives = 104/207 (49%), Gaps = 11/207 (5%)
Query: 426 GENLGAGAGGSVR--LMKRISDNQVFAVKEFRPKFEHESKRDYVKK-ITSEYCIGTTLRH 482
G NLG G+ V+ +R+ N AVK K ++ D+V++ + E I T+ H
Sbjct: 15 GINLGKGSYAKVKSAYSERLKFN--VAVKIIDRK---KTPTDFVERFLPREMDILATVNH 69
Query: 483 PNIISTIEIVYENN-RIFQVMEY-CDYDLFAIVMSNKMSYEEICC-CFKQILTGVEYLHS 539
+II T EI ++ RI+ +ME DL + +E++ F+Q+ + V+Y H
Sbjct: 70 GSIIKTYEIFETSDGRIYIIMELGVQGDLLEFIKCQGALHEDVARKMFRQLSSAVKYCHD 129
Query: 540 IGLAHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIF 599
+ + HRD+K +N +++ +KL DFG ++ + +I S GS Y APEV
Sbjct: 130 LDIVHRDLKCENLLLDKDFNIKLSDFGFSKRCLRDSNGRIILSKTFCGSAAYAAPEVLQS 189
Query: 600 TKYDPRPVDIWSVAILFACMVLKKFPW 626
Y P+ DIWS+ ++ MV P+
Sbjct: 190 IPYQPKVYDIWSLGVILYIMVCGSMPY 216
>At4g22940 [D] KOG0600 Cdc2-related protein kinase
Length = 458
Score = 83.2 bits (204), Expect = 1e-15
Identities = 53/200 (26%), Positives = 99/200 (49%), Gaps = 11/200 (5%)
Query: 417 PFSKRYLKTGENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCI 476
P + + + E +G G V + + N+ A+K R + +K I E I
Sbjct: 97 PGRESHFEKQEQIGGGTFSKVFKARDLLRNKTVALKRIRFDINNSES---IKCIAREIII 153
Query: 477 GTTLRHPNIISTIEIV---YENNRIFQVMEYCDYDLFAI--VMSNKMSYEEICCCFKQIL 531
L HPN+I ++ ++++ ++ + EY ++DL + ++ S ++ C +Q+L
Sbjct: 154 LRKLDHPNVIKLEGLMLVDHDSSTLYLIFEYMEHDLLGLSSLLGVHFSEPQVKCYMRQLL 213
Query: 532 TGVEYLHSIGLAHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPY 591
G+++ H+ + HRDMK N +IN G++K+ DFG A F PH+ + + V + Y
Sbjct: 214 RGLDHCHTNHVLHRDMKSSNLLINGDGVLKIADFGLATFFD-PHNSVPLTTH--VATLWY 270
Query: 592 LAPEVCIFTKYDPRPVDIWS 611
PE+ + + VD+WS
Sbjct: 271 RPPELLLGASHYGIGVDLWS 290
>7297080 [T] KOG0583 Serine/threonine protein kinase
Length = 329
Score = 83.2 bits (204), Expect = 1e-15
Identities = 47/149 (31%), Positives = 79/149 (52%), Gaps = 2/149 (1%)
Query: 480 LRHPNIISTIEIVYENNRIFQVMEYCDYD-LFAIVMSNKMSYE-EICCCFKQILTGVEYL 537
L H N+I+ + + ++R++ +M+ + L V K E + FKQ+++ VEY+
Sbjct: 123 LHHENLITFYQSIETSHRVYLIMQLAENGTLLDYVRERKFLDEPQSRTLFKQLVSAVEYI 182
Query: 538 HSIGLAHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVC 597
HS G+ HRD+K +N +++ +KLIDFG A + +I S GS Y +PE+
Sbjct: 183 HSKGVVHRDIKCENLLLDENWNLKLIDFGFARKDTRTSDNQVILSKTFCGSYAYASPEIL 242
Query: 598 IFTKYDPRPVDIWSVAILFACMVLKKFPW 626
YDP DIW+ ++ MV + P+
Sbjct: 243 KGVAYDPFMSDIWACGVVCYAMVFGRLPY 271
>SPCC18B5.11c [D] KOG0615 Serine/threonine protein kinase Chk2 and related
proteins
Length = 460
Score = 82.8 bits (203), Expect = 2e-15
Identities = 81/313 (25%), Positives = 133/313 (41%), Gaps = 59/313 (18%)
Query: 429 LGAGAGGSVRLMKRISDNQVFAVKEFRPK--FEHESKRDYVKKITSEYCIGTTLRHPNII 486
LG+G V+L ++ + +A+K + S++ + E I +L HP ++
Sbjct: 173 LGSGTFAVVKLAVEVNSGKWYAIKIINKRKILLTSSEKRATEMFQREIDILKSLHHPGVV 232
Query: 487 STIEIVYENNRIFQVMEYCDY-DLFAIVMSNKMSYEEICC-CFKQILTGVEYLHSIGLAH 544
EI ++ +F VMEY + DL +++N E+ C KQ+L + +LH G+ H
Sbjct: 233 QCHEIFENDDELFIVMEYVEGGDLMDFLIANGSIDEQDCKPLLKQLLETLLHLHKQGVTH 292
Query: 545 RDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVC------I 598
RD+K +N +I N +K+ DFG A+V + T +E+ G+ YLAPEV +
Sbjct: 293 RDIKPENILITNDFHLKISDFGLAKVIH--GTGTFLET--FCGTMGYLAPEVLKSKNVNL 348
Query: 599 FTKYDPRPVDIWSVAILFACMVLKKFPWKIPKLKDNSFKFFCSGRDCDSLSALVTKTPKP 658
YD + VDIWS+ + M+ P F S +
Sbjct: 349 DGGYDDK-VDIWSLGCVLYVMLTASIP-------------FASSSQAKCI---------- 384
Query: 659 PSYDNAVQSDEPAESTSKSNNPSDPNNTNIGPQRLLHSLPEETHHIIGRMVDLAPACRAN 718
E SK P +P L + + EE +I RM+++ P R +
Sbjct: 385 -------------ELISKGAYPIEP--------LLENEISEEGIDLINRMLEINPEKRIS 423
Query: 719 IEEVLNDPWIQSI 731
E L PW ++
Sbjct: 424 ESEALQHPWFYTV 436
>At5g44290 [D] KOG0600 Cdc2-related protein kinase
Length = 644
Score = 82.8 bits (203), Expect = 2e-15
Identities = 54/193 (27%), Positives = 99/193 (50%), Gaps = 10/193 (5%)
Query: 427 ENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLRHPNII 486
E +G G SV + +++N++ A+K R S + VK + E + L HPN++
Sbjct: 141 EKIGQGTYSSVYKARDLTNNKIVALKRVRFDL---SDLESVKFMAREIIVMRRLDHPNVL 197
Query: 487 STIEIVYEN--NRIFQVMEYCDYDL--FAIVMSNKMSYEEICCCFKQILTGVEYLHSIGL 542
++ + + ++ V EY D+DL A + K S ++ C +Q+L+G+ + HS G+
Sbjct: 198 KLEGLITASVSSSLYLVFEYMDHDLVGLASIPGIKFSEPQVKCYMQQLLSGLHHCHSRGV 257
Query: 543 AHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFTKY 602
HRD+K N +I++ G++K+ DFG A F + + + V + Y PE+ + +
Sbjct: 258 LHRDIKGSNLLIDSNGVLKIADFGLATFFD---PQNCVPLTSRVVTLWYRPPELLLGACH 314
Query: 603 DPRPVDIWSVAIL 615
VD+WS +
Sbjct: 315 YGVGVDLWSTGCI 327
>At5g07070 [T] KOG0583 Serine/threonine protein kinase
Length = 456
Score = 82.8 bits (203), Expect = 2e-15
Identities = 54/209 (25%), Positives = 103/209 (48%), Gaps = 6/209 (2%)
Query: 419 SKRYLKTGENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGT 478
++RY + G LG G V + N+ A+K + + ++I E +
Sbjct: 9 TERY-EVGRLLGQGTFAKVYFGRSNHTNESVAIKMIDK--DKVMRVGLSQQIKREISVMR 65
Query: 479 TLRHPNIISTIEIVYENNRIFQVMEYCDY-DLFAIVMSNKMSYEEICCCFKQILTGVEYL 537
+HPN++ E++ +RI+ V+EYC +LF V K+ + F Q+++ V++
Sbjct: 66 IAKHPNVVELYEVMATKSRIYFVIEYCKGGELFNKVAKGKLKEDVAWKYFYQLISAVDFC 125
Query: 538 HSIGLAHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVC 597
HS G+ HRD+K +N ++++ +K+ DFG + + L+ ++ G+ Y+APEV
Sbjct: 126 HSRGVYHRDIKPENLLLDDNDNLKVSDFGLSALADCKRQDGLLHTT--CGTPAYVAPEVI 183
Query: 598 IFTKYDPRPVDIWSVAILFACMVLKKFPW 626
Y+ DIWS ++ ++ P+
Sbjct: 184 NRKGYEGTKADIWSCGVVLFVLLAGYLPF 212
>At2g25090 [T] KOG0583 Serine/threonine protein kinase
Length = 469
Score = 82.8 bits (203), Expect = 2e-15
Identities = 60/210 (28%), Positives = 104/210 (48%), Gaps = 12/210 (5%)
Query: 426 GENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLRHPNI 485
G LG G V IS A+K + K +R +++I E + LRHPN+
Sbjct: 18 GRLLGTGNFAKVYHGTEISTGDDVAIKVIK-KDHVFKRRGMMEQIEREIAVMRLLRHPNV 76
Query: 486 ISTIEIVYENNRIFQVMEYCDY-DLFAIVMSNKMSYEEICC-CFKQILTGVEYLHSIGLA 543
+ E++ +IF VMEY + +LF ++ + E++ F+Q+++ V++ HS G+
Sbjct: 77 VELREVMATKKKIFFVMEYVNGGELFEMIDRDGKLPEDLARKYFQQLISAVDFCHSRGVF 136
Query: 544 HRDMKLDNCVINNQGIVKLIDFGAAEVF-------SYPHSKTLIESSGIVGSDPYLAPEV 596
HRD+K +N +++ +G +K+ DFG + + S L+ + G+ Y+APEV
Sbjct: 137 HRDIKPENLLLDGEGDLKVTDFGLSALMMPEGLGGRRGSSDDLLHTR--CGTPAYVAPEV 194
Query: 597 CIFTKYDPRPVDIWSVAILFACMVLKKFPW 626
YD DIWS I+ ++ P+
Sbjct: 195 LRNKGYDGAMADIWSCGIVLYALLAGFLPF 224
>SPAC1F3.02c [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 1116
Score = 82.4 bits (202), Expect = 2e-15
Identities = 75/271 (27%), Positives = 124/271 (45%), Gaps = 22/271 (8%)
Query: 426 GENLGAGAGGSVRLMKRISDNQVFAVKEFR-PKF----EHESKRDYVKKITSEYCIGTTL 480
GE +G G G V L I+ ++ AVK+ P+ + ++D V I +E + L
Sbjct: 828 GELIGNGTYGKVFLAMNINTGELIAVKQVEIPQTINGRHDQLRKDIVDSINAEISMIADL 887
Query: 481 RHPNIISTIEIVYENNRIFQVMEYCDYDLFAIVMSNKMSYEEICCCF--KQILTGVEYLH 538
H NI+ + I +EY + N +EE F +Q+L G+ YLH
Sbjct: 888 DHLNIVQYLGFEKTETDISIFLEYVSGGSIGRCLRNYGPFEEQLVRFVSRQVLYGLSYLH 947
Query: 539 SIGLAHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESS---GIVGSDPYLAPE 595
S G+ HRD+K DN +I+ G+ K+ DFG ++ HS + ++ + GS ++APE
Sbjct: 948 SKGIIHRDLKADNLLIDFDGVCKISDFGISK-----HSDNVYDNDANLSMQGSIFWMAPE 1002
Query: 596 VCIFTKYD--PRPVDIWSVAILFACMVLKKFPWKIPKLKDNSFKFFCSGRDCDSLSALVT 653
V I + VD+WS+ + M+ + PW + FK + S LV+
Sbjct: 1003 V-IHNDHQGYSAKVDVWSLGCVVLEMLAGRRPWSTDEAIQAMFKLGTEKKAPPIPSELVS 1061
Query: 654 K-TPKPPSYDNA---VQSDEPAESTSKSNNP 680
+ +P+ + NA V +D + N+P
Sbjct: 1062 QVSPEAIQFLNACFTVNADVRPTAEELLNHP 1092
>HsM8923212 [T] KOG4717 Serine/threonine protein kinase
Length = 244
Score = 82.4 bits (202), Expect = 2e-15
Identities = 59/207 (28%), Positives = 102/207 (48%), Gaps = 16/207 (7%)
Query: 427 ENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKK--ITSEYCIGTTLRHPN 484
+ LG G V+L + + + AVK ++K D + + E ++HPN
Sbjct: 20 KTLGRGHFAVVKLARHVFTGEKVAVKVI-----DKTKLDTLATGHLFQEVRCMKLVQHPN 74
Query: 485 IISTIEIVYENNRIFQVMEYCDY-DLFAIVMSNKMSYEEICC--CFKQILTGVEYLHSIG 541
I+ E++ +++ ++E D D+F +M ++ E F QI+ + Y H +
Sbjct: 75 IVRLYEVIDTQTKLYLILELGDGGDMFDYIMKHEEGLNEDLAKKYFAQIVHAISYCHKLH 134
Query: 542 LAHRDMKLDNCVI-NNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFT 600
+ HRD+K +N V QG+VKL DFG + F K L S G + Y APE+ +
Sbjct: 135 VVHRDLKPENVVFFEKQGLVKLTDFGFSNKFQ--PGKKLTTSCGSLA---YSAPEILLGD 189
Query: 601 KYDPRPVDIWSVAILFACMVLKKFPWK 627
+YD VDIWS+ ++ +V ++ P++
Sbjct: 190 EYDAPAVDIWSLGVILFMLVCEQPPFQ 216
>Hs4506785 [T] KOG0660 Mitogen-activated protein kinase
Length = 367
Score = 82.4 bits (202), Expect = 2e-15
Identities = 76/310 (24%), Positives = 132/310 (42%), Gaps = 35/310 (11%)
Query: 429 LGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLRHPNIIST 488
+G+GA G+V A+K+ F+ E + K+ E + +RH N+I
Sbjct: 33 VGSGAYGAVCSAVDGRTGAKVAIKKLYRPFQSEL---FAKRAYRELRLLKHMRHENVIGL 89
Query: 489 IEIVYENNRI------FQVMEYCDYDLFAIVMSNKMSYEEICCCFKQILTGVEYLHSIGL 542
+++ + + + VM + DL ++ K+ + I Q+L G+ Y+H+ G+
Sbjct: 90 LDVFTPDETLDDFTDFYLVMPFMGTDLGKLMKHEKLGEDRIQFLVYQMLKGLRYIHAAGI 149
Query: 543 AHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFTKY 602
HRD+K N +N +K++DFG A + E +G V + Y APEV +
Sbjct: 150 IHRDLKPGNLAVNEDCELKILDFGLAR-------QADSEMTGYVVTRWYRAPEVILNWMR 202
Query: 603 DPRPVDIWSVAILFACMVLKKFPWKIPKLKDNSFKFFCSGRDCDSLSALVTKTPKPPS-Y 661
+ VDIWSV + A M+ K F D L ++ T PP+ +
Sbjct: 203 YTQTVDIWSVGCIMAEMITGK-------------TLFKGSDHLDQLKEIMKVTGTPPAEF 249
Query: 662 DNAVQSDEPAESTSKSNNPSDPNNTNIGPQRLLHSLPEETHHIIGRMVDLAPACRANIEE 721
+QSDE +K+N P +L + +++ +M+ L R E
Sbjct: 250 VQRLQSDE-----AKNNMKGLPELEKKDFASILTNASPLAVNLLEKMLVLDAEQRVTAGE 304
Query: 722 VLNDPWIQSI 731
L P+ +S+
Sbjct: 305 ALAHPYFESL 314
>ECU11g1290 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 328
Score = 82.4 bits (202), Expect = 2e-15
Identities = 77/306 (25%), Positives = 140/306 (45%), Gaps = 24/306 (7%)
Query: 429 LGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLRHPNIIST 488
+ +G+ G+V ++R +DN+VFA+K P +++ + I E I +RH NI+
Sbjct: 32 ISSGSFGNVYRVRRKTDNRVFALKRMNPSMCYDTNGFSILYIR-EVMILKHIRHRNIMEI 90
Query: 489 IEIVY--ENNRIFQVMEYCDYDLFAIVMS-NKMSYEEICCCFKQILTGVEYLHSIGLAHR 545
E+V E N F VME CD DL +++ S K+ + Q+L G+++LH G+ HR
Sbjct: 91 EEVVEGCEINDFFIVMECCDTDLRSVIHSVGKIGMKAARFLTCQMLKGLKFLHGAGIVHR 150
Query: 546 DMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFTKYDPR 605
D+K N ++ G +++ DFG A + + +V + Y E+ + ++
Sbjct: 151 DLKPSNILLMRDGGLRIADFGLARAIE-------SQMTNLVVTLWYRPIEILLGSETYDE 203
Query: 606 PVDIWSVAILFACMV----LKKFPWKIPKLKDNSFKF--FCSGRDCDSLSALVTKTPKPP 659
+D+WSV + M+ + ++ +L D F+ + + D + L K + P
Sbjct: 204 SIDMWSVGCVVGEMLRGEPILAGEGEMDQL-DRIFRLLGYPTDADFEGLDLPHFKNIRRP 262
Query: 660 S-YDNAVQSD-----EPAESTSKSNNPSDPNNTNIGPQRLLHSLPEETHHIIGRMVDLAP 713
S ++ + + D E A S ++ DP Q L + G +VD+
Sbjct: 263 STFEASFEGDFECYGEEAASFVRNLLSFDPRKRCTASQGLCSGFVADAEECPGELVDIVG 322
Query: 714 ACRANI 719
C +I
Sbjct: 323 RCTGDI 328
>At5g45820 [T] KOG0583 Serine/threonine protein kinase
Length = 439
Score = 82.4 bits (202), Expect = 2e-15
Identities = 53/207 (25%), Positives = 98/207 (46%), Gaps = 5/207 (2%)
Query: 421 RYLKTGENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTL 480
R + G LG G V + I + A+K + +K + +I E + +
Sbjct: 10 RKYELGRLLGQGTFAKVYHARNIKTGESVAIKVIDK--QKVAKVGLIDQIKREISVMRLV 67
Query: 481 RHPNIISTIEIVYENNRIFQVMEYCDY-DLFAIVMSNKMSYEEICCCFKQILTGVEYLHS 539
RHP+++ E++ +I+ MEY +LF V K+ F+Q++ ++Y HS
Sbjct: 68 RHPHVVFLHEVMASKTKIYFAMEYVKGGELFDKVSKGKLKENIARKYFQQLIGAIDYCHS 127
Query: 540 IGLAHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIF 599
G+ HRD+K +N +++ G +K+ DFG + + L+ ++ G+ Y+APEV
Sbjct: 128 RGVYHRDLKPENLLLDENGDLKISDFGLSALRESKQQDGLLHTT--CGTPAYVAPEVIGK 185
Query: 600 TKYDPRPVDIWSVAILFACMVLKKFPW 626
YD D+WS ++ ++ P+
Sbjct: 186 KGYDGAKADVWSCGVVLYVLLAGFLPF 212
>At3g21220 [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K)
Length = 348
Score = 82.4 bits (202), Expect = 2e-15
Identities = 56/215 (26%), Positives = 107/215 (49%), Gaps = 14/215 (6%)
Query: 423 LKTGENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLRH 482
L+ +G+GAGG+V + ++ FA+K E +R ++I I ++ H
Sbjct: 70 LERVNRIGSGAGGTVYKVIHTPTSRPFALKVIYGNHEDTVRRQICREIE----ILRSVDH 125
Query: 483 PNIISTIEIVYENNRIFQVMEYCDYDLFAIVMSNKMSYEEICCCFKQILTGVEYLHSIGL 542
PN++ ++ N I ++E+ D ++ ++ +E+ +QIL+G+ YLH +
Sbjct: 126 PNVVKCHDMFDHNGEIQVLLEFMDQG--SLEGAHIWQEQELADLSRQILSGLAYLHRRHI 183
Query: 543 AHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPE----VCI 598
HRD+K N +IN+ VK+ DFG + + ++T+ + VG+ Y++PE
Sbjct: 184 VHRDIKPSNLLINSAKNVKIADFGVSRIL----AQTMDPCNSSVGTIAYMSPERINTDLN 239
Query: 599 FTKYDPRPVDIWSVAILFACMVLKKFPWKIPKLKD 633
+YD D+WS+ + L +FP+ + + D
Sbjct: 240 HGRYDGYAGDVWSLGVSILEFYLGRFPFAVSRQGD 274
>At1g53570 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 608
Score = 82.4 bits (202), Expect = 2e-15
Identities = 58/205 (28%), Positives = 92/205 (44%), Gaps = 7/205 (3%)
Query: 424 KTGENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLRHP 483
K G+ LG+G G V L ++ A+KE + + ++ ++ +K++ E + L HP
Sbjct: 215 KKGKFLGSGTFGQVYLGFNSEKGKMCAIKEVKVISDDQTSKECLKQLNQEINLLNQLCHP 274
Query: 484 NIISTIEIVYENNRIFQVMEYCDYDLFAIVMSNKMSYEE--ICCCFKQILTGVEYLHSIG 541
NI+ + +EY ++ + S+ E I +QIL G+ YLH
Sbjct: 275 NIVQYYGSELSEETLSVYLEYVSGGSIHKLLKDYGSFTEPVIQNYTRQILAGLAYLHGRN 334
Query: 542 LAHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFTK 601
HRD+K N +++ G +KL DFG A+ H GS ++APEV +
Sbjct: 335 TVHRDIKGANILVDPNGEIKLADFGMAK-----HVTAFSTMLSFKGSPYWMAPEVVMSQN 389
Query: 602 YDPRPVDIWSVAILFACMVLKKFPW 626
VDIWS+ M K PW
Sbjct: 390 GYTHAVDIWSLGCTILEMATSKPPW 414
>7297680 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 297
Score = 82.4 bits (202), Expect = 2e-15
Identities = 79/314 (25%), Positives = 132/314 (41%), Gaps = 48/314 (15%)
Query: 427 ENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLRHPNII 486
E +G G G V + Q+ A+K+ R + + E + E + L+H NI+
Sbjct: 8 EKIGEGTYGVVYKGRNRLTGQIVAMKKIRLESDDEGVPSTAIR---EISLLKELKHENIV 64
Query: 487 STIEIVYENNRIFQVMEYCDYDLF----AIVMSNKMSYEEICCCFKQILTGVEYLHSIGL 542
+++ E NRI+ + E+ DL ++ + M E + QI + + + H +
Sbjct: 65 CLEDVLMEENRIYLIFEFLSMDLKKYMDSLPVDKHMESELVRSYLYQITSAILFCHRRRV 124
Query: 543 AHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFTKY 602
HRD+K N +I+ G++K+ DFG F P I + IV + Y APEV + +
Sbjct: 125 LHRDLKPQNLLIDKSGLIKVADFGLGRSFGIP---VRIYTHEIV-TLWYRAPEVLLGSPR 180
Query: 603 DPRPVDIWSVAILFACMVLKKFPWKIPKLKDNSFKFFCSGRDCDSLSALVTKTPKP---- 658
PVDIWS+ +FA M +K ++ D F+ F + KTP
Sbjct: 181 YSCPVDIWSIGCIFAEMATRKPLFQGDSEIDQLFRMF-----------RILKTPTEDIWP 229
Query: 659 -----PSYDNAVQSDEPAESTSKSNNPSDPNNTNIGPQRLLHSLPEETHHIIGRMVDLAP 713
P Y N P ST++ N L +L +I +M+ P
Sbjct: 230 GVTSLPDYKNTF----PCWSTNQLTNQ-------------LKNLDANGIDLIQKMLIYDP 272
Query: 714 ACRANIEEVLNDPW 727
R + +++L P+
Sbjct: 273 VHRISAKDILEHPY 286
>Hs4758652 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 358
Score = 82.0 bits (201), Expect = 3e-15
Identities = 60/203 (29%), Positives = 102/203 (49%), Gaps = 16/203 (7%)
Query: 420 KRYLKTGENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRD-YVKKIT-SEYCIG 477
++Y K G+ +G G+ G V + Q+ A+K+F ES+ D +KKI E +
Sbjct: 3 EKYEKIGK-IGEGSYGVVFKCRNRDTGQIVAIKKFL-----ESEDDPVIKKIALREIRML 56
Query: 478 TTLRHPNIISTIEIVYENNRIFQVMEYCDYDLFAIVMSNKMSYEE--ICCCFKQILTGVE 535
L+HPN+++ +E+ R+ V EYCD+ + + + E + Q L V
Sbjct: 57 KQLKHPNLVNLLEVFRRKRRLHLVFEYCDHTVLHELDRYQRGVPEHLVKSITWQTLQAVN 116
Query: 536 YLHSIGLAHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPE 595
+ H HRD+K +N +I ++KL DFG A + + P + V + Y +PE
Sbjct: 117 FCHKHNCIHRDVKPENILITKHSVIKLCDFGFARLLTGPSD----YYTDYVATRWYRSPE 172
Query: 596 VCI-FTKYDPRPVDIWSVAILFA 617
+ + T+Y P PVD+W++ +FA
Sbjct: 173 LLVGDTQYGP-PVDVWAIGCVFA 194
>Hs4505695 [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 556
Score = 82.0 bits (201), Expect = 3e-15
Identities = 67/246 (27%), Positives = 120/246 (48%), Gaps = 20/246 (8%)
Query: 414 PALPFSKRY--LKTGENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKIT 471
P P KR K G+ LG G+ +V L + ++ ++ +A+K + H K + V +T
Sbjct: 71 PPQPRKKRPEDFKFGKILGEGSFSTVVLARELATSREYAIKILEKR--HIIKENKVPYVT 128
Query: 472 SEYCIGTTLRHPNIISTIEIVYENNRIFQVMEYCDYDLFAIVMSNKMSYEEICCCF--KQ 529
E + + L HP + ++ +++ + Y + S++E C F +
Sbjct: 129 RERDVMSRLDHPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAE 188
Query: 530 ILTGVEYLHSIGLAHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSD 589
I++ +EYLH G+ HRD+K +N ++N +++ DFG A+V S P SK ++ VG+
Sbjct: 189 IVSALEYLHGKGIIHRDLKPENILLNEDMHIQITDFGTAKVLS-PESKQ-ARANSFVGTA 246
Query: 590 PYLAPEVCIFTKYDPRPVDIWSVAILFACMVLKKFPW----------KIPKLK-DNSFKF 638
Y++PE+ + K + D+W++ + +V P+ KI KL+ D KF
Sbjct: 247 QYVSPEL-LTEKSACKSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYDFPEKF 305
Query: 639 FCSGRD 644
F RD
Sbjct: 306 FPKARD 311
>CE20564 [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 540
Score = 82.0 bits (201), Expect = 3e-15
Identities = 59/195 (30%), Positives = 98/195 (50%), Gaps = 11/195 (5%)
Query: 427 ENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLRHPNII 486
+ +G G+ G V +IS Q+ AVK R + +R+ + +E I +HPNI+
Sbjct: 253 KQIGEGSTGVVEAAYKISTKQIVAVK--RMNLRKQQRREL---LFNEVSILRQYQHPNIV 307
Query: 487 STIEIVYENNRIFQVMEYCDY-DLFAIVMSNKMSYEEICCCFKQILTGVEYLHSIGLAHR 545
++ ++ VME+ + L IV + +M+ +I +Q+L +++LH+ + HR
Sbjct: 308 RFFSSHLVDDELWVVMEFMEGGSLTDIVTATRMTEPQIATISRQVLGALDFLHARKVIHR 367
Query: 546 DMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFTKYDPR 605
D+K D+ ++ G VKL DFG F S+ + +VG+ + A EV YD R
Sbjct: 368 DIKSDSILLKRDGTVKLTDFG----FCGQLSEEVPRRRSLVGTPYWTAAEVIAREPYDTR 423
Query: 606 PVDIWSVAILFACMV 620
DIWS I+ MV
Sbjct: 424 -ADIWSFGIMLIEMV 437
>CE05425 [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 542
Score = 82.0 bits (201), Expect = 3e-15
Identities = 59/195 (30%), Positives = 98/195 (50%), Gaps = 11/195 (5%)
Query: 427 ENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLRHPNII 486
+ +G G+ G V +IS Q+ AVK R + +R+ + +E I +HPNI+
Sbjct: 255 KQIGEGSTGVVEAAYKISTKQIVAVK--RMNLRKQQRREL---LFNEVSILRQYQHPNIV 309
Query: 487 STIEIVYENNRIFQVMEYCDY-DLFAIVMSNKMSYEEICCCFKQILTGVEYLHSIGLAHR 545
++ ++ VME+ + L IV + +M+ +I +Q+L +++LH+ + HR
Sbjct: 310 RFFSSHLVDDELWVVMEFMEGGSLTDIVTATRMTEPQIATISRQVLGALDFLHARKVIHR 369
Query: 546 DMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFTKYDPR 605
D+K D+ ++ G VKL DFG F S+ + +VG+ + A EV YD R
Sbjct: 370 DIKSDSILLKRDGTVKLTDFG----FCGQLSEEVPRRRSLVGTPYWTAAEVIAREPYDTR 425
Query: 606 PVDIWSVAILFACMV 620
DIWS I+ MV
Sbjct: 426 -ADIWSFGIMLIEMV 439
>At1g33770 [D] KOG0600 Cdc2-related protein kinase
Length = 614
Score = 82.0 bits (201), Expect = 3e-15
Identities = 59/197 (29%), Positives = 101/197 (50%), Gaps = 14/197 (7%)
Query: 427 ENLGAGAGGSVRLMKRISDNQVFAVKEFR-PKFEHESKRDYVKKITSEYCIGTTLRHPNI 485
+ +G G V + + ++ A+K+ R + ES R ++I I L HPN+
Sbjct: 145 DKIGQGTYSIVYKARDLETGKIVAMKKVRFANMDPESVRFMAREIN----ILRKLDHPNV 200
Query: 486 ISTIEIVYE--NNRIFQVMEYCDYDLFAIVMSNKMSYEE--ICCCFKQILTGVEYLHSIG 541
+ +V + + V EY ++DL + + + + E I C KQ+L G+E+ HS G
Sbjct: 201 MKLQCLVTSKLSGSLHLVFEYMEHDLSGLALRPGVKFTEPQIKCFMKQLLCGLEHCHSRG 260
Query: 542 LAHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCI-FT 600
+ HRD+K N ++NN G++K+ DFG A + + L + V + Y APE+ + T
Sbjct: 261 ILHRDIKGSNLLVNNDGVLKIGDFGLASFYKPDQDQPL---TSRVVTLWYRAPELLLGST 317
Query: 601 KYDPRPVDIWSVAILFA 617
+Y P +D+WSV + A
Sbjct: 318 EYGP-AIDLWSVGCILA 333
>SPBC1D7.05c [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 362
Score = 81.6 bits (200), Expect = 4e-15
Identities = 61/208 (29%), Positives = 101/208 (48%), Gaps = 8/208 (3%)
Query: 426 GENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVK---KITSEYCIGTTLRH 482
G +G+G+ G V L S ++ AVK+ ESK + K + E + L H
Sbjct: 100 GALIGSGSFGQVYLGMNASSGELMAVKQVILDSVSESKDRHAKLLDALAGEIALLQELSH 159
Query: 483 PNIISTIEIVYENNRIFQVMEYCDYDLFAIVMSNKMSYEEICC--CFKQILTGVEYLHSI 540
+I+ + ++ + +EY A +++ S+EE KQ L G+EYLHS
Sbjct: 160 EHIVQYLGSNLNSDHLNIFLEYVPGGSVAGLLTMYGSFEETLVKNFIKQTLKGLEYLHSR 219
Query: 541 GLAHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESS--GIVGSDPYLAPEVCI 598
G+ HRD+K N +++N+G +K+ DFG ++ + T + GS ++APEV
Sbjct: 220 GIVHRDIKGANILVDNKGKIKISDFGISKKLELNSTSTKTGGARPSFQGSSFWMAPEVVK 279
Query: 599 FTKYDPRPVDIWSVAILFACMVLKKFPW 626
T + + DIWS+ L M+ K P+
Sbjct: 280 QTMHTEK-TDIWSLGCLVIEMLTSKHPY 306
>Hs4826675 [UT] KOG0662 Cyclin-dependent kinase CDK5
Length = 292
Score = 81.6 bits (200), Expect = 4e-15
Identities = 55/193 (28%), Positives = 91/193 (46%), Gaps = 9/193 (4%)
Query: 427 ENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLRHPNII 486
E +G G G+V K +++ A+K R + E + E C+ L+H NI+
Sbjct: 8 EKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALR---EICLLKELKHKNIV 64
Query: 487 STIEIVYENNRIFQVMEYCDYDL--FAIVMSNKMSYEEICCCFKQILTGVEYLHSIGLAH 544
++++ + ++ V E+CD DL + + + E + Q+L G+ + HS + H
Sbjct: 65 RLHDVLHSDKKLTLVFEFCDQDLKKYFDSCNGDLDPEIVKSFLFQLLKGLGFCHSRNVLH 124
Query: 545 RDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFTKYDP 604
RD+K N +IN G +KL DFG A F P + S V + Y P+V K
Sbjct: 125 RDLKPQNLLINRNGELKLADFGLARAFGIP----VRCYSAEVVTLWYRPPDVLFGAKLYS 180
Query: 605 RPVDIWSVAILFA 617
+D+WS +FA
Sbjct: 181 TSIDMWSAGCIFA 193
>Hs14042966 [T] KOG0583 Serine/threonine protein kinase
Length = 273
Score = 81.6 bits (200), Expect = 4e-15
Identities = 62/208 (29%), Positives = 97/208 (45%), Gaps = 13/208 (6%)
Query: 424 KTGENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKK-ITSEYCIGTTLRH 482
K G +G G+ V++ A+K + + D+V K + E I +RH
Sbjct: 13 KLGRTIGEGSYSKVKVATSKKYKGTVAIKVVDRR---RAPPDFVNKFLPRELSILRGVRH 69
Query: 483 PNIISTIEIVYE-NNRIFQVMEYCDYDLFAIVMSN-KMSYEEICCCFKQILTGVEYLHSI 540
P+I+ E + N +++ VME DL V N ++ + F QI V YLH
Sbjct: 70 PHIVHVFEFIEVCNGKLYIVMEAAATDLLQAVQRNGRIPGVQARDLFAQIAGAVRYLHDH 129
Query: 541 GLAHRDMKLDNCVIN-NQGIVKLIDFG-AAEVFSYPHSKTLIESSGIVGSDPYLAPEVCI 598
L HRD+K +N +++ ++ VKL DFG + YP T GS Y +PEV +
Sbjct: 130 HLVHRDLKCENVLLSPDERRVKLTDFGFGRQAHGYPDLSTTY-----CGSAAYASPEVLL 184
Query: 599 FTKYDPRPVDIWSVAILFACMVLKKFPW 626
YDP+ D+WS+ ++ MV P+
Sbjct: 185 GIPYDPKKYDVWSMGVVLYVMVTGCMPF 212
>CE28643 [T] KOG0583 Serine/threonine protein kinase
Length = 564
Score = 81.6 bits (200), Expect = 4e-15
Identities = 62/203 (30%), Positives = 99/203 (48%), Gaps = 11/203 (5%)
Query: 427 ENLGAGAGGSVRLMKRISDNQVFAVKEF-RPKFEHESKRDYVKKITSEYCIGTTLRHPNI 485
E LG G G V++ + AVK R K + D V KI E + RHP+I
Sbjct: 29 ETLGVGTFGKVKVGIHETTQYKVAVKILNRQKIK---SLDVVGKIRREIQNLSLFRHPHI 85
Query: 486 ISTIEIVYENNRIFQVMEYCDY-DLFA-IVMSNKMSYEEICCCFKQILTGVEYLHSIGLA 543
I +++ + IF +ME+ +LF IV ++ E F+QI++GV+Y H +
Sbjct: 86 IRLYQVISTPSDIFMIMEHVSGGELFDYIVKHGRLKTAEARRFFQQIISGVDYCHRHMVV 145
Query: 544 HRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFTKYD 603
HRD+K +N +++ Q VK+ DFG + + + + +S GS Y APEV Y
Sbjct: 146 HRDLKPENLLLDEQNNVKIADFGLSNIMT---DGDFLRTS--CGSPNYAAPEVISGKLYA 200
Query: 604 PRPVDIWSVAILFACMVLKKFPW 626
VD+WS ++ ++ P+
Sbjct: 201 GPEVDVWSCGVILYALLCGTLPF 223
>CE07458 [T] KOG0583 Serine/threonine protein kinase
Length = 562
Score = 81.6 bits (200), Expect = 4e-15
Identities = 62/203 (30%), Positives = 99/203 (48%), Gaps = 11/203 (5%)
Query: 427 ENLGAGAGGSVRLMKRISDNQVFAVKEF-RPKFEHESKRDYVKKITSEYCIGTTLRHPNI 485
E LG G G V++ + AVK R K + D V KI E + RHP+I
Sbjct: 29 ETLGVGTFGKVKVGIHETTQYKVAVKILNRQKIK---SLDVVGKIRREIQNLSLFRHPHI 85
Query: 486 ISTIEIVYENNRIFQVMEYCDY-DLFA-IVMSNKMSYEEICCCFKQILTGVEYLHSIGLA 543
I +++ + IF +ME+ +LF IV ++ E F+QI++GV+Y H +
Sbjct: 86 IRLYQVISTPSDIFMIMEHVSGGELFDYIVKHGRLKTAEARRFFQQIISGVDYCHRHMVV 145
Query: 544 HRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFTKYD 603
HRD+K +N +++ Q VK+ DFG + + + + +S GS Y APEV Y
Sbjct: 146 HRDLKPENLLLDEQNNVKIADFGLSNIMT---DGDFLRTS--CGSPNYAAPEVISGKLYA 200
Query: 604 PRPVDIWSVAILFACMVLKKFPW 626
VD+WS ++ ++ P+
Sbjct: 201 GPEVDVWSCGVILYALLCGTLPF 223
>At5g56580 [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K)
Length = 356
Score = 81.6 bits (200), Expect = 4e-15
Identities = 68/267 (25%), Positives = 125/267 (46%), Gaps = 28/267 (10%)
Query: 423 LKTGENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLRH 482
L+T + +G G+GG V+L++ + FA+K + + E ++ V+++ + +
Sbjct: 70 LETVKVIGKGSGGVVQLVRHKWVGKFFAMKVIQMNIQEEIRKQIVQELKINQA---SSQC 126
Query: 483 PNIISTIEIVYENNRIFQVMEYCDYDLFAIVMSNKMSYEE--ICCCFKQILTGVEYLHSI 540
P+++ Y N V+EY D A V+ + E + KQ+L G+ YLH+
Sbjct: 127 PHVVVCYHSFYHNGAFSLVLEYMDRGSLADVIRQVKTILEPYLAVVCKQVLLGLVYLHNE 186
Query: 541 G-LAHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIF 599
+ HRD+K N ++N++G VK+ DFG S + ++ + VG+ Y++PE
Sbjct: 187 RHVIHRDIKPSNLLVNHKGEVKISDFGV----SASLASSMGQRDTFVGTYNYMSPERISG 242
Query: 600 TKYDPRPVDIWSVAILFACMVLKKFPWKIPKLKDNSFKFFCSGRDCDSLSALVTKTPKPP 659
+ YD DIWS+ + + +FP+ + + N F+ + L+A+V P
Sbjct: 243 STYD-YSSDIWSLGMSVLECAIGRFPYLESEDQQNPPSFY------ELLAAIVENPPPTA 295
Query: 660 SYDN-----------AVQSDEPAESTS 675
D +Q D PA ++S
Sbjct: 296 PSDQFSPEFCSFVSACIQKDPPARASS 322
>At1g50230 [R] KOG0597 Serine-threonine protein kinase FUSED
Length = 269
Score = 81.6 bits (200), Expect = 4e-15
Identities = 63/191 (32%), Positives = 101/191 (51%), Gaps = 11/191 (5%)
Query: 427 ENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLRHPNII 486
E +G G+ G V +R Q A+K + + + + + E I L+H NII
Sbjct: 10 ELVGEGSFGRVYKGRRKYTGQTVAMKFIMKQGKTDKD---IHSLRQEIEILRKLKHENII 66
Query: 487 STIEIVYENNRIFQVM-EYCDYDLFAIVMSNK-MSYEEICCCFKQILTGVEYLHSIGLAH 544
++ +EN R F V+ E+ +LF I+ +K + E++ KQ++ ++YLHS + H
Sbjct: 67 EMLDS-FENAREFCVVTEFAQGELFEILEDDKCLPEEQVQAIAKQLVKALDYLHSNRIIH 125
Query: 545 RDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFTKYDP 604
RDMK N +I +VKL DFG A S + T++ S I G+ Y+APE+ YD
Sbjct: 126 RDMKPQNILIGAGSVVKLCDFGFARAMS---TNTVVLRS-IKGTPLYMAPELVKEQPYD- 180
Query: 605 RPVDIWSVAIL 615
R VD+WS+ ++
Sbjct: 181 RTVDLWSLGVI 191
>7301110 [T] KOG0660 Mitogen-activated protein kinase
Length = 366
Score = 81.6 bits (200), Expect = 4e-15
Identities = 77/339 (22%), Positives = 140/339 (40%), Gaps = 43/339 (12%)
Query: 429 LGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLRHPNIIST 488
+G+GA G V N A+K+ F+ + K+ E + + H N+I
Sbjct: 31 VGSGAYGQVSKAVVRGTNMHVAIKKLARPFQSAV---HAKRTYRELRLLKHMDHENVIGL 87
Query: 489 IEIVYEN---------NRIFQVMEYCDYDLFAIVMSNKMSYEEICCCFKQILTGVEYLHS 539
++I + + +++ V D DL I+ +S + + QIL G++Y+HS
Sbjct: 88 LDIFHPHPANGSLENFQQVYLVTHLMDADLNNIIRMQHLSDDHVQFLVYQILRGLKYIHS 147
Query: 540 IGLAHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIF 599
G+ HRD+K N +N ++++DFG A T E +G V + Y APE+ +
Sbjct: 148 AGVIHRDLKPSNIAVNEDCELRILDFGLAR-------PTENEMTGYVATRWYRAPEIMLN 200
Query: 600 TKYDPRPVDIWSVAILFACMVLKKFPWKIPKLKDNSFKFFCSGRDCDSLSALVTKTPKPP 659
+ + VDIWSV + A ++ ++ F L+ ++ PP
Sbjct: 201 WMHYDQTVDIWSVGCIMAELITRR-------------TLFPGTDHIHQLNLIMEMLGTPP 247
Query: 660 SYDNAVQSDEPAESTSKSNNPSDPNNTNIGPQRLLHSLPEETHHIIGRMVDLAPACRANI 719
+ S E A S +S P + + + + ++ +M++L R
Sbjct: 248 AEFLKKISSESARSYIQSLPPMKGRSF----KNVFKNANPLAIDLLEKMLELDAEKRITA 303
Query: 720 EEVLNDPWIQSIDMCTVEVDNQGNYVVHPGMDHKHTQVD 758
EE L+ P+++ +VE + P DH +D
Sbjct: 304 EEALSHPYLEKYAEPSVEQTS-------PPYDHSFEDMD 335
>7296128 [T] KOG0583 Serine/threonine protein kinase
Length = 550
Score = 81.6 bits (200), Expect = 4e-15
Identities = 52/174 (29%), Positives = 86/174 (48%), Gaps = 17/174 (9%)
Query: 467 VKKITSEYCIGTTLRHPNIISTIEIVYENNRIFQVMEYC-DYDLFA-IVMSNKMSYEEIC 524
++ ++SE + HPNI+ E+V R++ V E+ +L+ I +
Sbjct: 87 LRMLSSEIATLECVHHPNILRLFEVVETLGRVYLVTEWIRGGELYNHITQGGPLREIHAA 146
Query: 525 CCFKQILTGVEYLHSIGLAHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSG 584
KQ+L V+++HS+G HRD+K +N ++ ++ +KL DFG S LI +G
Sbjct: 147 PLLKQLLLAVKHMHSLGYVHRDIKAENVLLLSEDRLKLADFG--------FSTQLINGTG 198
Query: 585 -------IVGSDPYLAPEVCIFTKYDPRPVDIWSVAILFACMVLKKFPWKIPKL 631
GS PY APE+ Y PVD+W++ IL MV+ P++ P +
Sbjct: 199 ANQKLDTFCGSPPYAAPELFSDDHYIGAPVDVWALGILLYFMVVGNMPFRAPTI 252
>7295173 [T] KOG0664 Nemo-like MAPK-related serine/threonine protein kinase
Length = 474
Score = 81.6 bits (200), Expect = 4e-15
Identities = 75/321 (23%), Positives = 144/321 (44%), Gaps = 31/321 (9%)
Query: 414 PALPFSKRYLKTGENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSE 473
PA+P + ++ +G GA G V + D + A+K+ F+ V +
Sbjct: 34 PAVP---QDVQPDRPIGYGAFGVVWAVTDPRDGRRVALKKLPNVFQSLVSSKRVFRELKM 90
Query: 474 YCIGTTLRHPNIISTIEIVYENN-----RIFQVMEYCDYDLFAIVMSNK-MSYEEICCCF 527
C +H N++S ++I+ + I+ + E DL I++S + +S + I
Sbjct: 91 LCF---FKHENVLSALDILQPPHLDFFQEIYVITELLQSDLHKIIVSPQHLSADHIKVFL 147
Query: 528 KQILTGVEYLHSIGLAHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVG 587
QIL G++YLHS + HRD+K N ++N+ ++K+ DFG A V +K + + V
Sbjct: 148 YQILRGLKYLHSARILHRDIKPGNLLVNSNCVLKICDFGLARVEEPDQAKHMTQE---VV 204
Query: 588 SDPYLAPEVCIFTKYDPRPVDIWSVAILFACMVLKKFPWKIPKLKDNSFKFFCSGRDCDS 647
+ Y APE+ + ++ VD+WSV +F ++ ++ F +
Sbjct: 205 TQYYRAPEILMGARHYSSAVDVWSVGCIFGELLGRRI-------------LFQAQNPVQQ 251
Query: 648 LSALVTKTPKPPSYDNAVQSDEPAESTSKSNNPSDPNNTNIGPQRLLHSLPEETHHIIGR 707
L L+T+ P+ ++ + E A + P P+ + + L E H++ +
Sbjct: 252 LE-LITELLGTPTMEDMRHACEGARTHMLRRAPKPPSFSVL--YTLSSHATHEAVHLLCQ 308
Query: 708 MVDLAPACRANIEEVLNDPWI 728
M+ P R ++ + L P++
Sbjct: 309 MLVFDPDKRISVTDALAHPYL 329
>7293601 [T] KOG0577 Serine/threonine protein kinase
Length = 1039
Score = 81.6 bits (200), Expect = 4e-15
Identities = 60/205 (29%), Positives = 102/205 (49%), Gaps = 20/205 (9%)
Query: 429 LGAGAGGSVRLMKRISDNQVFAVKE--FRPKFEHESKRDYVKKITSEYCIGTTLRHPNII 486
+G G+ G+V + ++ A+K+ + K E +D +K+I L HPN I
Sbjct: 33 IGHGSFGAVYYARCNLTREIVAIKKMSYTGKQSQEKWQDILKEIR----FLRQLNHPNTI 88
Query: 487 STIEIVYENNRIFQVMEYCDYDLFAIVMSNK--MSYEEICCCFKQILTGVEYLHSIGLAH 544
+ + VMEYC I+ +K + +EI +L+G+ YLHS+G H
Sbjct: 89 EYKGCYLRESTAWLVMEYCVGSASDIIEVHKKPLHEDEIAAICLGVLSGLSYLHSLGRIH 148
Query: 545 RDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFT---K 601
RD+K N ++ + G+VKL DFG+A + ++ VG+ ++APEV + +
Sbjct: 149 RDIKAGNILLTDNGVVKLADFGSAAI--------KCPANSFVGTPYWMAPEVILAMDEGQ 200
Query: 602 YDPRPVDIWSVAILFACMVLKKFPW 626
YD + VD+WS+ I + +K P+
Sbjct: 201 YDGK-VDVWSLGITCIELAERKPPY 224
>YOL045w [T] KOG1152 Signal transduction serine/threonine kinase with PAS/PAC
sensor domain
Length = 1101
Score = 81.3 bits (199), Expect = 5e-15
Identities = 72/253 (28%), Positives = 123/253 (48%), Gaps = 27/253 (10%)
Query: 429 LGAGAGGSVRLMKRISDNQVFAVKE-FRPKFEHES--KRDYVKKITSEYCIGTTLR---H 482
+G GA G V L ++ + +K F+ + ++ + + I SE I TL
Sbjct: 847 MGEGAYGKVNLCIHNREHYIVVIKMIFKERILVDTWVRDRKLGTIPSEIQIMATLNKNSQ 906
Query: 483 PNIISTIEIVYENNRIFQVM-----EYCDYDLFAIVMSNK-MSYEEICCCFKQILTGVEY 536
NI+ ++ +E++ + + E DLF ++ K M E FKQ++ +++
Sbjct: 907 ENILKLLDF-FEDDDYYYIETPVHGETGSIDLFDVIEFKKDMVEHEAKLVFKQVVASIKH 965
Query: 537 LHSIGLAHRDMKLDNCVINNQGIVKLIDFG-AAEVFSYPHSKTLIESSGIVGSDPYLAPE 595
LH G+ HRD+K +N ++++ G VKLIDFG AA + S P VG+ Y APE
Sbjct: 966 LHDQGIVHRDIKDENVIVDSHGFVKLIDFGSAAYIKSGPFDV-------FVGTMDYAAPE 1018
Query: 596 VCIFTKYDPRPVDIWSVAILFACMVLKKFP-WKIPKLKDNSFKFFCS---GRDCDSL--S 649
V + Y +P DIW++ +L ++ K+ P + I ++ + +F S +C SL
Sbjct: 1019 VLGGSSYKGKPQDIWALGVLLYTIIYKENPYYNIDEILEGELRFDKSEHVSEECISLIKR 1078
Query: 650 ALVTKTPKPPSYD 662
L + K P+ D
Sbjct: 1079 ILTREVDKRPTID 1091
>YKL139w [D] KOG0600 Cdc2-related protein kinase
Length = 528
Score = 81.3 bits (199), Expect = 5e-15
Identities = 58/192 (30%), Positives = 97/192 (50%), Gaps = 15/192 (7%)
Query: 429 LGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITS--EYCIGTTLRHPNII 486
+G G G V K + ++ A+K+ R + E E ITS E + + HPN+
Sbjct: 189 VGEGTYGKVYKAKNTNTEKLVALKKLRLQGEREGF-----PITSIREIKLLQSFDHPNVS 243
Query: 487 STIEIVYENNR-IFQVMEYCDYDLFAIVMSNKMSYEEICC--CFKQILTGVEYLHSIGLA 543
+ EI+ E+ + ++ + EY D DL ++++ ++ C FKQ+L G+EYLH +
Sbjct: 244 TIKEIMVESQKTVYMIFEYADNDLSGLLLNKEVQISHSQCKHLFKQLLLGMEYLHDNKIL 303
Query: 544 HRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFTKYD 603
HRD+K N +I+NQG +K+ DFG A + + + + V + Y PE+ + T
Sbjct: 304 HRDVKGSNILIDNQGNLKITDFGLARKMN-----SRADYTNRVITLWYRPPELLLGTTNY 358
Query: 604 PRPVDIWSVAIL 615
VD+W L
Sbjct: 359 GTEVDMWGCGCL 370
>CE27899 [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 318
Score = 81.3 bits (199), Expect = 5e-15
Identities = 62/218 (28%), Positives = 102/218 (46%), Gaps = 18/218 (8%)
Query: 429 LGAGAGGSVRLMKRISDNQV-FAVKEFRPKFEHESKRDYVKKITSEYCIGTTLR----HP 483
L G G V L + + V AVK+ + E +V+ I +E+ I L H
Sbjct: 27 LSEGTYGQVSLYESSKNPDVKIAVKQISTAGQSER---FVEHIKTEFAIHKGLSKIGGHR 83
Query: 484 NIISTIEIVYENNRIFQVMEYCDY-DLFAIVMSNKMSYEEIC-CCFKQILTGVEYLHSIG 541
N+IS +E+ ++ + EY D DLF + + Y E C FKQ+++G++++H
Sbjct: 84 NVISMMEMRKGSDCYTLLKEYADGGDLFKKLETEGEQYSENAQCFFKQLISGLKFIHEHE 143
Query: 542 LAHRDMKLDNCVINNQ------GIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPE 595
+ HRD+KL+N ++ +K+ DFG A + + ++ + GS PY APE
Sbjct: 144 IVHRDIKLENLLLMKSKSNLVPDTLKIADFGLATEYMVDGEELMLVDN--CGSPPYAAPE 201
Query: 596 VCIFTKYDPRPVDIWSVAILFACMVLKKFPWKIPKLKD 633
V + P D+WS ++ M+ PW KD
Sbjct: 202 VYSKQGHRGPPTDVWSSGVILMAMLTAGLPWDCAHRKD 239
>Hs19311016_1 [R] KOG0589 Serine/threonine protein kinase
Length = 330
Score = 81.3 bits (199), Expect = 5e-15
Identities = 57/201 (28%), Positives = 97/201 (47%), Gaps = 15/201 (7%)
Query: 429 LGAGAGGSVRLMKRISDNQVFAVKEFR-PKFEHESKRDYVKKITSEYCIGTTLRHPNIIS 487
LG GA G L +R D+ + KE + + +RD + +I I L+H NII+
Sbjct: 58 LGRGAFGEATLYRRTEDDSLVVWKEVDLTRLSEKERRDALNEIV----ILALLQHDNIIA 113
Query: 488 TIEIVYENNRIFQVMEYCD----YDLFAIVMSNKMSYEEICCCFKQILTGVEYLHSIGLA 543
+N + +EYC+ YD E + QI++ V +H G+
Sbjct: 114 YYNHFMDNTTLLIELEYCNGGNLYDKILRQKDKLFEEEMVVWYLFQIVSAVSCIHKAGIL 173
Query: 544 HRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFTKYD 603
HRD+K N + ++KL D+G A+ + +S + +VG+ Y++PE+C KY+
Sbjct: 174 HRDIKTLNIFLTKANLIKLGDYGLAKKLNSEYSM----AETLVGTPYYMSPELCQGVKYN 229
Query: 604 PRPVDIWSV-AILFACMVLKK 623
+ DIW+V ++F + LK+
Sbjct: 230 FKS-DIWAVGCVIFELLTLKR 249
>SPAC2F3.15 [D] KOG0600 Cdc2-related protein kinase
Length = 593
Score = 80.9 bits (198), Expect = 7e-15
Identities = 62/204 (30%), Positives = 98/204 (47%), Gaps = 14/204 (6%)
Query: 427 ENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLRHPNII 486
+ +G G G V + A+K R + E K + E I LRH NI+
Sbjct: 281 DQIGEGTYGKVYKAINTVTGDLVALKRIRLEQE---KDGFPITTVREVKILQRLRHKNIV 337
Query: 487 STIEIVYENNRIFQVMEYCDYDLFAIVMSNKMSYE--EICCCFKQILTGVEYLHSIGLAH 544
+EI+ E + ++ V EY D+DL +++++++ + I KQI + YLH G+ H
Sbjct: 338 RLLEIMVEKSSVYMVFEYMDHDLTGVLLNSQLHFTPGNIKHLSKQIFEALAYLHHRGVLH 397
Query: 545 RDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCI-FTKYD 603
RD+K N ++NN G +K DFG A + S + V + + PE+ + T YD
Sbjct: 398 RDIKGSNILLNNNGDLKFADFGLAR---FNTSSKSANYTNRVITLWFRPPELLLGETAYD 454
Query: 604 PRPVDIWSVAILFACMVLKKFPWK 627
VDIWS C+V++ F K
Sbjct: 455 -TAVDIWSA----GCIVMELFTGK 473
>Hs7706401 [T] KOG0577 Serine/threonine protein kinase
Length = 1235
Score = 80.9 bits (198), Expect = 7e-15
Identities = 59/204 (28%), Positives = 103/204 (49%), Gaps = 20/204 (9%)
Query: 429 LGAGAGGSVRLMKRISDNQVFAVKE--FRPKFEHESKRDYVKKITSEYCIGTTLRHPNII 486
+G G+ G+V + + +++V A+K+ + K +E +D +K++ LRHPN I
Sbjct: 34 IGHGSFGAVYFARDVRNSEVVAIKKMSYSGKQSNEKWQDIIKEVR----FLQKLRHPNTI 89
Query: 487 STIEIVYENNRIFQVMEYCDYDLFAIVMSNKMSYEE--ICCCFKQILTGVEYLHSIGLAH 544
+ + VMEYC ++ +K +E I L G+ YLHS + H
Sbjct: 90 QYRGCYLREHTAWLVMEYCLGSASDLLEVHKKPLQEVEIAAVTHGALQGLAYLHSHNMIH 149
Query: 545 RDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFT---K 601
RD+K N +++ G+VKL DFG+A + + ++ VG+ ++APEV + +
Sbjct: 150 RDVKAGNILLSEPGLVKLGDFGSASI--------MAPANSFVGTPYWMAPEVILAMDEGQ 201
Query: 602 YDPRPVDIWSVAILFACMVLKKFP 625
YD + VD+WS+ I + +K P
Sbjct: 202 YDGK-VDVWSLGITCIELAERKPP 224
>Hs4759208 [T] KOG0577 Serine/threonine protein kinase
Length = 1049
Score = 80.9 bits (198), Expect = 7e-15
Identities = 59/204 (28%), Positives = 103/204 (49%), Gaps = 20/204 (9%)
Query: 429 LGAGAGGSVRLMKRISDNQVFAVKE--FRPKFEHESKRDYVKKITSEYCIGTTLRHPNII 486
+G G+ G+V + + +++V A+K+ + K +E +D +K++ LRHPN I
Sbjct: 34 IGHGSFGAVYFARDVRNSEVVAIKKMSYSGKQSNEKWQDIIKEVR----FLQKLRHPNTI 89
Query: 487 STIEIVYENNRIFQVMEYCDYDLFAIVMSNKMSYEE--ICCCFKQILTGVEYLHSIGLAH 544
+ + VMEYC ++ +K +E I L G+ YLHS + H
Sbjct: 90 QYRGCYLREHTAWLVMEYCLGSASDLLEVHKKPLQEVEIAAVTHGALQGLAYLHSHNMIH 149
Query: 545 RDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFT---K 601
RD+K N +++ G+VKL DFG+A + + ++ VG+ ++APEV + +
Sbjct: 150 RDVKAGNILLSEPGLVKLGDFGSASI--------MAPANSFVGTPYWMAPEVILAMDEGQ 201
Query: 602 YDPRPVDIWSVAILFACMVLKKFP 625
YD + VD+WS+ I + +K P
Sbjct: 202 YDGK-VDVWSLGITCIELAERKPP 224
>Hs4506081 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 422
Score = 80.9 bits (198), Expect = 7e-15
Identities = 82/326 (25%), Positives = 143/326 (43%), Gaps = 47/326 (14%)
Query: 423 LKTGENL---GAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTT 479
LK +NL G+GA G V ++ A+K+ F++++ + K+ E +
Sbjct: 61 LKRYQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRPFQNQT---HAKRAYRELVLMKC 117
Query: 480 LRHPNIISTIEI------VYENNRIFQVMEYCDYDLFAIVMSNKMSYEEICCCFKQILTG 533
+ H NIIS + + + E ++ VME D +L ++ ++ +E + Q+L G
Sbjct: 118 VNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQM-ELDHERMSYLLYQMLCG 176
Query: 534 VEYLHSIGLAHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLA 593
+++LHS G+ HRD+K N V+ + +K++DFG A + T + V + Y A
Sbjct: 177 IKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLART-----AGTSFMMTPYVVTRYYRA 231
Query: 594 PEVCIFTKYDPRPVDIWSVAILFACMVLKKFPWKIPKLKDNSFKFFCSGRD-CDSLSALV 652
PEV + Y VDIWSV + MV K GRD D + ++
Sbjct: 232 PEVILGMGYKEN-VDIWSVGCIMGEMV--------------RHKILFPGRDYIDQWNKVI 276
Query: 653 TKTPKP-PSYDNAVQSDEPAESTSKSNNPSDPNNT--NIGPQRLLHSLPE-------ETH 702
+ P P + +Q P N P T + P L + E +
Sbjct: 277 EQLGTPCPEFMKKLQ---PTVRNYVENRPKYAGLTFPKLFPDSLFPADSEHNKLKASQAR 333
Query: 703 HIIGRMVDLAPACRANIEEVLNDPWI 728
++ +M+ + PA R ++++ L P+I
Sbjct: 334 DLLSKMLVIDPAKRISVDDALQHPYI 359
>Hs20986510 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 464
Score = 80.9 bits (198), Expect = 7e-15
Identities = 82/326 (25%), Positives = 143/326 (43%), Gaps = 47/326 (14%)
Query: 423 LKTGENL---GAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTT 479
LK +NL G+GA G V ++ A+K+ F++++ + K+ E +
Sbjct: 61 LKRYQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRPFQNQT---HAKRAYRELVLMKC 117
Query: 480 LRHPNIISTIEI------VYENNRIFQVMEYCDYDLFAIVMSNKMSYEEICCCFKQILTG 533
+ H NIIS + + + E ++ VME D +L ++ ++ +E + Q+L G
Sbjct: 118 VNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQM-ELDHERMSYLLYQMLCG 176
Query: 534 VEYLHSIGLAHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLA 593
+++LHS G+ HRD+K N V+ + +K++DFG A + T + V + Y A
Sbjct: 177 IKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLART-----AGTSFMMTPYVVTRYYRA 231
Query: 594 PEVCIFTKYDPRPVDIWSVAILFACMVLKKFPWKIPKLKDNSFKFFCSGRD-CDSLSALV 652
PEV + Y VDIWSV + MV K GRD D + ++
Sbjct: 232 PEVILGMGYKEN-VDIWSVGCIMGEMV--------------RHKILFPGRDYIDQWNKVI 276
Query: 653 TKTPKP-PSYDNAVQSDEPAESTSKSNNPSDPNNT--NIGPQRLLHSLPE-------ETH 702
+ P P + +Q P N P T + P L + E +
Sbjct: 277 EQLGTPCPEFMKKLQ---PTVRNYVENRPKYAGLTFPKLFPDSLFPADSEHNKLKASQAR 333
Query: 703 HIIGRMVDLAPACRANIEEVLNDPWI 728
++ +M+ + PA R ++++ L P+I
Sbjct: 334 DLLSKMLVIDPAKRISVDDALQHPYI 359
>Hs20986506 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 426
Score = 80.9 bits (198), Expect = 7e-15
Identities = 82/326 (25%), Positives = 143/326 (43%), Gaps = 47/326 (14%)
Query: 423 LKTGENL---GAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTT 479
LK +NL G+GA G V ++ A+K+ F++++ + K+ E +
Sbjct: 23 LKRYQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRPFQNQT---HAKRAYRELVLMKC 79
Query: 480 LRHPNIISTIEI------VYENNRIFQVMEYCDYDLFAIVMSNKMSYEEICCCFKQILTG 533
+ H NIIS + + + E ++ VME D +L ++ ++ +E + Q+L G
Sbjct: 80 VNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQM-ELDHERMSYLLYQMLCG 138
Query: 534 VEYLHSIGLAHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLA 593
+++LHS G+ HRD+K N V+ + +K++DFG A + T + V + Y A
Sbjct: 139 IKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLART-----AGTSFMMTPYVVTRYYRA 193
Query: 594 PEVCIFTKYDPRPVDIWSVAILFACMVLKKFPWKIPKLKDNSFKFFCSGRD-CDSLSALV 652
PEV + Y VDIWSV + MV K GRD D + ++
Sbjct: 194 PEVILGMGYKEN-VDIWSVGCIMGEMV--------------RHKILFPGRDYIDQWNKVI 238
Query: 653 TKTPKP-PSYDNAVQSDEPAESTSKSNNPSDPNNT--NIGPQRLLHSLPE-------ETH 702
+ P P + +Q P N P T + P L + E +
Sbjct: 239 EQLGTPCPEFMKKLQ---PTVRNYVENRPKYAGLTFPKLFPDSLFPADSEHNKLKASQAR 295
Query: 703 HIIGRMVDLAPACRANIEEVLNDPWI 728
++ +M+ + PA R ++++ L P+I
Sbjct: 296 DLLSKMLVIDPAKRISVDDALQHPYI 321
>7297578 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 822
Score = 80.9 bits (198), Expect = 7e-15
Identities = 55/200 (27%), Positives = 100/200 (49%), Gaps = 14/200 (7%)
Query: 421 RYLKTGENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTL 480
RY+ T LG G G+V L +R + A+K + K+ + ++++ S L
Sbjct: 3 RYI-TLTQLGDGTYGTVVLGQRKDTGEKVAIKRMKRKYYSWEEAMNLREVKSL----KKL 57
Query: 481 RHPNIISTIEIVYENNRIFQVMEYCDYDLFAIVMSNK--MSYEEICCCFKQILTGVEYLH 538
HPNI+ E++ EN+ ++ V EY +L+ ++ + E+ Q+LTG+ ++H
Sbjct: 58 SHPNIVKLKEVIRENDTLYFVFEYMKENLYQMIKDRDTHLPEPELKSILFQVLTGLAFMH 117
Query: 539 SIGLAHRDMKLDNCVINNQGIVKLIDFG-AAEVFSYPHSKTLIESSGIVGSDPYLAPEVC 597
G HRD+K +N + + ++K+ DFG A E+ S P + V + Y APEV
Sbjct: 118 RHGFFHRDLKPENLLCSGPDLIKIADFGLAREIRSRP------PFTDYVSTRWYRAPEVL 171
Query: 598 IFTKYDPRPVDIWSVAILFA 617
+ + +D+W++ + A
Sbjct: 172 LHSTNYGSTIDLWAMGCIMA 191
>7293666 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 576
Score = 80.9 bits (198), Expect = 7e-15
Identities = 62/210 (29%), Positives = 97/210 (45%), Gaps = 11/210 (5%)
Query: 432 GAGGSVRLMKRIS--DNQVFAVKEFRPKFEHESKRDYVKKITSEYCIGTTLRHPNIISTI 489
G GG + + I + VFA K K K + +K E I +L HPNI+
Sbjct: 32 GKGGFAKCYEIIDVETDDVFAGKIVSKKLM--IKHNQKEKTAQEITIHRSLNHPNIVKFH 89
Query: 490 EIVYENNRIFQVMEYCDYDLFAIVMSNKMSYEEICCCFK--QILTGVEYLHSIGLAHRDM 547
++ I+ V+E C + + S E C + QI+ GV+YLH + HRD+
Sbjct: 90 NYFEDSQNIYIVLELCKKRSMMELHKRRKSITEFECRYYIYQIIQGVKYLHDNRIIHRDL 149
Query: 548 KLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFTKYDPRPV 607
KL N +N+ VK+ DFG A Y + + G+ Y+APE+ + K V
Sbjct: 150 KLGNLFLNDLLHVKIGDFGLATRIEYEGER----KKTLCGTPNYIAPEI-LTKKGHSFEV 204
Query: 608 DIWSVAILFACMVLKKFPWKIPKLKDNSFK 637
DIWS+ + +++ + P++ LKD K
Sbjct: 205 DIWSIGCVMYTLLVGQPPFETKTLKDTYSK 234
>7290150 [T] KOG0583 Serine/threonine protein kinase
Length = 582
Score = 80.9 bits (198), Expect = 7e-15
Identities = 62/205 (30%), Positives = 98/205 (47%), Gaps = 13/205 (6%)
Query: 426 GENLGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKR--DYVKKITSEYCIGTTLRHP 483
G LG G G V+ I ++Q+ VK + + D V KI E RHP
Sbjct: 31 GATLGTGTFGKVK----IGEHQITRVKVAVKILNRQKIKSLDVVGKIRREIQNLKLFRHP 86
Query: 484 NIISTIEIVYENNRIFQVMEYCDY-DLFA-IVMSNKMSYEEICCCFKQILTGVEYLHSIG 541
+II +++ + IF +MEY +LF IV K+ + F+QI++GV+Y H
Sbjct: 87 HIIKLYQVISTPSDIFMIMEYVSGGELFDYIVKHGKLQEHQARRFFQQIISGVDYCHRHM 146
Query: 542 LAHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFTK 601
+ HRD+K +N ++++ VK+ DFG + + + +S GS Y APEV
Sbjct: 147 IVHRDLKPENLLLDHNMHVKIADFGLSNMML---DGEFLRTS--CGSPNYAAPEVISGKL 201
Query: 602 YDPRPVDIWSVAILFACMVLKKFPW 626
Y VDIWS ++ ++ P+
Sbjct: 202 YAGPEVDIWSCGVILYALLCGTLPF 226
>YDR122w [T] KOG0583 Serine/threonine protein kinase
Length = 1064
Score = 80.5 bits (197), Expect = 9e-15
Identities = 63/228 (27%), Positives = 100/228 (43%), Gaps = 35/228 (15%)
Query: 427 ENLGAGAGGSVRLMKRISDNQVFAVK--------------------------EFRPKFEH 460
E +GAG+ G V+L K N+V AVK E + K E
Sbjct: 124 ETVGAGSMGKVKLAKHRYTNEVCAVKIVNRATKAFLHKEQMLPPPKNEQDVLERQKKLEK 183
Query: 461 ESKRDYVKKITSEYCIGTTLRHPNIISTIEIVYENNRIFQVMEYCDYD--LFAIVMSNKM 518
E RD K+ E +G L HP+I E+ +N + + EY L I+ +
Sbjct: 184 EISRD--KRTIREASLGQILYHPHICRLFEMCTLSNHFYMLFEYVSGGQLLDYIIQHGSI 241
Query: 519 SYEEICCCFKQILTGVEYLHSIGLAHRDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKT 578
+ + I + + YLH+ + HRD+K++N +I++ +K+IDFG + + Y K
Sbjct: 242 REHQARKFARGIASALIYLHANNIVHRDLKIENIMISDSSEIKIIDFGLSNI--YDSRKQ 299
Query: 579 LIESSGIVGSDPYLAPEVCIFTKYDPRPVDIWSVAILFACMVLKKFPW 626
L GS + APE+ Y VD+WS ++ +V K P+
Sbjct: 300 L---HTFCGSLYFAAPELLKANPYTGPEVDVWSFGVVLFVLVCGKVPF 344
>Hs4505569 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 493
Score = 80.5 bits (197), Expect = 9e-15
Identities = 56/200 (28%), Positives = 99/200 (49%), Gaps = 17/200 (8%)
Query: 429 LGAGAGGSVRLMKRISDNQVFAVKEFRPKFEHESKRD-YVKKITS-EYCIGTTLRHPNII 486
+G G+ G V + ++ A+K+F ES D VKKI E + LRH N++
Sbjct: 10 VGEGSYGMVMKCRNKDTGRIVAIKKFL-----ESDDDKMVKKIAMREIKLLKQLRHENLV 64
Query: 487 STIEIVYENNRIFQVMEYCDYDLF--AIVMSNKMSYEEICCCFKQILTGVEYLHSIGLAH 544
+ +E+ + R + V E+ D+ + + N + Y+ + QI+ G+ + HS + H
Sbjct: 65 NLLEVCKKKKRWYLVFEFVDHTILDDLELFPNGLDYQVVQKYLFQIINGIGFCHSHNIIH 124
Query: 545 RDMKLDNCVINNQGIVKLIDFGAAEVFSYPHSKTLIESSGIVGSDPYLAPEVCIFTKYDP 604
RD+K +N +++ G+VKL DFG A + P + V + Y APE+ +
Sbjct: 125 RDIKPENILVSQSGVVKLCDFGFARTLAAPGE----VYTDYVATRWYRAPELLVGDVKYG 180
Query: 605 RPVDIWSVAILFACMVLKKF 624
+ VD+W++ C+V + F
Sbjct: 181 KAVDVWAI----GCLVTEMF 196
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.313 0.130 0.378
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 40,805,896
Number of Sequences: 60738
Number of extensions: 1645577
Number of successful extensions: 7630
Number of sequences better than 1.0e-05: 1114
Number of HSP's better than 0.0 without gapping: 88
Number of HSP's successfully gapped in prelim test: 1026
Number of HSP's that attempted gapping in prelim test: 6043
Number of HSP's gapped (non-prelim): 1410
length of query: 774
length of database: 30,389,216
effective HSP length: 114
effective length of query: 660
effective length of database: 23,465,084
effective search space: 15486955440
effective search space used: 15486955440
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)