ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIV2114 check: MH O KOG1870 Posttranslational modification, protein turnover, chaperones Ubiquitin C-terminal hydrolase
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIV2114 720298 718049 -750
(750 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YNL186w [O] KOG1870 Ubiquitin C-terminal hydrolase 543 e-154
SPCC1682.12c [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 162 2e-39
YMR223w [O] KOG1867 Ubiquitin-specific protease 139 2e-32
At3g14400 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 136 1e-31
Hs20540195 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 132 2e-30
7295432 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 129 2e-29
At5g10790 [O] KOG1867 Ubiquitin-specific protease 122 2e-27
Hs13435157 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 121 3e-27
At1g17110 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 121 3e-27
Hs22055583 [O] KOG1867 Ubiquitin-specific protease 119 2e-26
CE11978 [O] KOG1870 Ubiquitin C-terminal hydrolase 117 6e-26
At3g49600_2 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase 116 1e-25
At4g31670 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 116 1e-25
Hs22044543 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 115 2e-25
Hs22044547 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 115 2e-25
Hs22044530 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 115 2e-25
At5g65450 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 115 2e-25
Hs5730108 [O] KOG1870 Ubiquitin C-terminal hydrolase 115 3e-25
Hs22044565 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 115 3e-25
Hs22044559 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 115 3e-25
Hs22044551 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 115 3e-25
Hs22044541 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 114 5e-25
Hs22044539 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 114 5e-25
Hs22065367 [O] KOG1867 Ubiquitin-specific protease 114 7e-25
HsM18874088 [O] KOG1870 Ubiquitin C-terminal hydrolase 113 9e-25
Hs21489975 [O] KOG1870 Ubiquitin C-terminal hydrolase 113 9e-25
7295645 [O] KOG1868 Ubiquitin C-terminal hydrolase 112 2e-24
Hs4827054 [O] KOG1868 Ubiquitin C-terminal hydrolase 111 4e-24
Hs22044534 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 111 4e-24
SPAC13A11.04c [O] KOG1867 Ubiquitin-specific protease 111 5e-24
Hs22044537 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 110 6e-24
Hs18557591 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 109 1e-23
At4g24560 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 109 2e-23
7293885 [O] KOG1867 Ubiquitin-specific protease 109 2e-23
HsM19923759 [O] KOG1868 Ubiquitin C-terminal hydrolase 108 2e-23
7300711 [O] KOG1868 Ubiquitin C-terminal hydrolase 107 7e-23
Hs22044528 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 106 1e-22
YER098w [O] KOG1864 Ubiquitin-specific protease 105 3e-22
YBL067c [O] KOG1864 Ubiquitin-specific protease 105 3e-22
Hs21361712 [O] KOG1868 Ubiquitin C-terminal hydrolase 105 3e-22
At5g46740 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 104 4e-22
Hs5730110 [O] KOG1867 Ubiquitin-specific protease 103 1e-21
At2g24640 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 102 2e-21
Hs12383078 [O] KOG1864 Ubiquitin-specific protease 101 4e-21
At2g22310 [O] KOG1864 Ubiquitin-specific protease 101 4e-21
Hs20548613 [O] KOG1864 Ubiquitin-specific protease 97 7e-20
At4g17890_2 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 96 2e-19
At4g39910 [O] KOG1864 Ubiquitin-specific protease 95 3e-19
Hs18860907_1 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase 94 6e-19
Hs6912742 [O] KOG1868 Ubiquitin C-terminal hydrolase 93 1e-18
7303210 [O] KOG1870 Ubiquitin C-terminal hydrolase 93 2e-18
SPBC1703.12 [O] KOG1864 Ubiquitin-specific protease 92 3e-18
Hs14149817 [O] KOG1867 Ubiquitin-specific protease 91 5e-18
HsM7706755 [O] KOG1868 Ubiquitin C-terminal hydrolase 91 8e-18
YDR069c [O] KOG1868 Ubiquitin C-terminal hydrolase 90 1e-17
Hs22044555 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 89 3e-17
CE13964 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 87 7e-17
At5g57990 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 85 4e-16
7292013_2 [O] KOG1871 Ubiquitin-specific protease 85 4e-16
CE26241 [O] KOG1867 Ubiquitin-specific protease 84 6e-16
YER144c [O] KOG1868 Ubiquitin C-terminal hydrolase 82 2e-15
At2g40930 [O] KOG1870 Ubiquitin C-terminal hydrolase 82 3e-15
Hs21265129 [O] KOG1868 Ubiquitin C-terminal hydrolase 81 7e-15
CE23922 [O] KOG1864 Ubiquitin-specific protease 79 2e-14
CE26210 [O] KOG1868 Ubiquitin C-terminal hydrolase 79 3e-14
Hs21361749 [O] KOG1867 Ubiquitin-specific protease 78 4e-14
Hs22067085 [O] KOG1871 Ubiquitin-specific protease 78 6e-14
7303452 [O] KOG1864 Ubiquitin-specific protease 77 7e-14
Hs4507853 [O] KOG1870 Ubiquitin C-terminal hydrolase 77 1e-13
7300926 [O] KOG1864 Ubiquitin-specific protease 76 2e-13
7295436 [O] KOG4598 Putative ubiquitin-specific protease 76 2e-13
Hs22043041 [O] KOG1866 Ubiquitin carboxyl-terminal hydrolase 75 3e-13
7292738 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase 75 3e-13
Hs14149627 [O] KOG1870 Ubiquitin C-terminal hydrolase 75 4e-13
Hs8394519 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase 73 1e-12
Hs14776897 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase 72 3e-12
CE23923 [O] KOG1864 Ubiquitin-specific protease 71 5e-12
Hs22045513 [O] KOG1868 Ubiquitin C-terminal hydrolase 71 7e-12
Hs4507857 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase 70 2e-11
Hs22068900 [O] KOG1870 Ubiquitin C-terminal hydrolase 70 2e-11
At4g10590 [O] KOG1870 Ubiquitin C-terminal hydrolase 70 2e-11
At4g10570 [O] KOG1870 Ubiquitin C-terminal hydrolase 70 2e-11
SPBC18H10.08c [O] KOG1868 Ubiquitin C-terminal hydrolase 69 2e-11
YJL197w [O] KOG1870 Ubiquitin C-terminal hydrolase 69 3e-11
SPBP8B7.21 [O] KOG1871 Ubiquitin-specific protease 69 3e-11
CE15615 [O] KOG1872 Ubiquitin-specific protease 68 5e-11
7291841 [O] KOG1870 Ubiquitin C-terminal hydrolase 68 5e-11
Hs22044589 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 68 6e-11
Hs20472401 [O] KOG1870 Ubiquitin C-terminal hydrolase 68 6e-11
Hs4759290 [O] KOG1870 Ubiquitin C-terminal hydrolase 67 1e-10
ECU07g0410 [O] KOG1868 Ubiquitin C-terminal hydrolase 67 1e-10
7302097 [O] KOG1866 Ubiquitin carboxyl-terminal hydrolase 66 2e-10
Hs10190742 [O] KOG1868 Ubiquitin C-terminal hydrolase 65 3e-10
Hs22047537 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 65 4e-10
CE29636 [O] KOG1870 Ubiquitin C-terminal hydrolase 65 4e-10
CE29635 [O] KOG1870 Ubiquitin C-terminal hydrolase 65 4e-10
HsM4507851 [O] KOG1864 Ubiquitin-specific protease 64 7e-10
Hs21361110 [O] KOG1864 Ubiquitin-specific protease 64 7e-10
Hs14777500 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase 64 7e-10
At1g32850 [O] KOG1870 Ubiquitin C-terminal hydrolase 64 8e-10
Hs22056581 [O] KOG1868 Ubiquitin C-terminal hydrolase 64 1e-09
SPCC1494.05c [O] KOG1870 Ubiquitin C-terminal hydrolase 61 6e-09
ECU03g0580 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase 61 6e-09
CE13299 [O] KOG4598 Putative ubiquitin-specific protease 61 7e-09
CE03146 [O] KOG1870 Ubiquitin C-terminal hydrolase 61 7e-09
At2g32780 [O] KOG1873 Ubiquitin-specific protease 61 7e-09
CE19500 [O] KOG1870 Ubiquitin C-terminal hydrolase 60 1e-08
At3g21280 [O] KOG1872 Ubiquitin-specific protease 60 1e-08
Hs22063256 [O] KOG1870 Ubiquitin C-terminal hydrolase 60 2e-08
At1g51710 [O] KOG1872 Ubiquitin-specific protease 60 2e-08
SPCC16A11.12c [O] KOG1870 Ubiquitin C-terminal hydrolase 59 4e-08
Hs5454156 [O] KOG1873 Ubiquitin-specific protease 57 8e-08
7290583 [O] KOG1873 Ubiquitin-specific protease 57 8e-08
YKR098c [O] KOG1868 Ubiquitin C-terminal hydrolase 57 1e-07
Hs13994268 [O] KOG1868 Ubiquitin C-terminal hydrolase 57 1e-07
7293523 [Z] KOG2026 Spindle pole body protein - Sad1p 55 3e-07
At1g04860 [O] KOG1873 Ubiquitin-specific protease 55 4e-07
Hs22047539 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 55 5e-07
7292313 [O] KOG0944 Ubiquitin-specific protease UBP14 53 2e-06
Hs20483065 [O] KOG1864 Ubiquitin-specific protease 51 7e-06
>YNL186w [O] KOG1870 Ubiquitin C-terminal hydrolase
Length = 792
Score = 543 bits (1398), Expect = e-154
Identities = 276/424 (65%), Positives = 316/424 (74%), Gaps = 39/424 (9%)
Query: 328 SSFYQFNESINDHGSNKPQRIVKNWGSKLTQLKPRGLLNHGVTCYTNAAVQAMVHIPAIQ 387
S+FYQFNE+IND GS RIVKNWG K T LKPRGLLNHGVTCYTNAAVQAM+HIP+IQ
Sbjct: 328 SNFYQFNENINDRGSLNSTRIVKNWGDKFTNLKPRGLLNHGVTCYTNAAVQAMLHIPSIQ 387
Query: 388 HYLFQLLRGNFKDTVKSNCVSMLLAETTMRMW---SSDSTKN---TYINPDKLINALEDI 441
HYLF +L G + T+ N VS LAET+ +MW S + KN +YINP LI+ L+DI
Sbjct: 388 HYLFDILMGKYDSTISKNSVSYTLAETSKKMWLPVSKNPRKNVSASYINPKHLISRLDDI 447
Query: 442 NCMMSAWNQEDSHEYFMSLMSRLQEDSVPKGHKMTESIIYDVFGGLLQQSVKCSNCGEIS 501
NCMMS W QEDSHEYFMSLMSRLQEDSVPKGHK+ ESIIYD+FGGLL+Q V C +CG IS
Sbjct: 448 NCMMSEWQQEDSHEYFMSLMSRLQEDSVPKGHKLIESIIYDIFGGLLKQIVTCKSCGSIS 507
Query: 502 TTEQPIYDLSLHLKGRKTTDQDQN------------------------SVGQDNSID--- 534
TEQP YDLSLHLKG+K D + + S+ +S++
Sbjct: 508 KTEQPFYDLSLHLKGKKKLDPNSDLSSDSINGTSATTSTTTSNAATKPSLSSSSSVNLNN 567
Query: 535 ----NSVDQQQSSKRRFSIEKSIRDFFNPELIKRVDNKEGYTCEKCKKVTNALKSNKIIR 590
+ S+ RRFSIEKSI+DFFNPELIK ++GY CEKC K TNA+K + I+R
Sbjct: 568 GSPFAAASDLSSANRRFSIEKSIKDFFNPELIKVDKEQKGYVCEKCHKTTNAVKHSSILR 627
Query: 591 APETLVVHLKKFRFNGTSSSKMKQAVSYPMFLDLTEYCHESISSLPVRYQLISVVVHEGR 650
APETL+VHLKKFRFNGTSSSKMKQAVSYPMFLDLTEYC LPV+YQL+SVVVHEGR
Sbjct: 628 APETLLVHLKKFRFNGTSSSKMKQAVSYPMFLDLTEYCES--KELPVKYQLLSVVVHEGR 685
Query: 651 SLSSGHYIAHCKQPDGSWATYDDEYINKISEKQLLKEPNAYFLVYTRLTPKSVPLSSQSS 710
SLSSGHYIAHCKQPDGSWATYDDEYIN ISE+ +LKEPNAY+L+YTRLTPKSVPL S
Sbjct: 686 SLSSGHYIAHCKQPDGSWATYDDEYINIISERDVLKEPNAYYLLYTRLTPKSVPLPLAKS 745
Query: 711 NKST 714
+T
Sbjct: 746 AMAT 749
Score = 55.5 bits (132), Expect = 3e-07
Identities = 53/165 (32%), Positives = 75/165 (45%), Gaps = 46/165 (27%)
Query: 3 DSVKPLVDRIVSQPLEFKKAVQEDSYN-----VGGEGSSYIMISSSTQKQQQEAKEGDEH 57
+S+KPLVDRI+S PL+F A+ + N E SSYI+I G +H
Sbjct: 5 ESIKPLVDRILSNPLQFNAAMISNKSNNNDTSAAPENSSYIVI-------------GKQH 51
Query: 58 QLEHGHHQGIAATATASR------------KEKVVKPSSFAEALKMYTTK--KSAANAAE 103
+ + IAATA + + K+ P S AEAL +YT+K K AA+A
Sbjct: 52 N-NNSNSTAIAATAESKQIKENNLIDRPNGKKTNTVPKSMAEALLLYTSKNDKDAADATG 110
Query: 104 SKPNRSSQLPITASHVTPSGKLSIGLSNELLLSDDDYHGSSTEDE 148
+K +S++L S PS S+DD G E+E
Sbjct: 111 AK--KSAELSTELSTEPPSSS-----------SEDDKVGKEEEEE 142
>SPCC1682.12c [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 457
Score = 162 bits (409), Expect = 2e-39
Identities = 110/360 (30%), Positives = 172/360 (47%), Gaps = 48/360 (13%)
Query: 363 GLLNHGVTCYTNAAVQAMVHIPAIQHYLFQLLRGNFKDTVKSN-CVSMLLAETTMRMWSS 421
GL+N G TC+ N+ +Q M P + YL L G + + N CV + + R + +
Sbjct: 126 GLVNLGNTCFMNSVLQLMTQTPPLVQYL---LSGQHSLSCRMNACVLCRMEQHVARAYPN 182
Query: 422 DSTKN-TYINPDKLINALEDINCMMSAWNQEDSHEYFMSLMSRLQEDSVPKGHKMTE--- 477
TK + P + + L+ I+ + QED+HE+ L+ Q+ + + HK +
Sbjct: 183 KGTKRASAFKPSGIQSMLKVISSHFRPYRQEDAHEFMRYLVDAWQKSCL-QNHKNLDHPS 241
Query: 478 ---SIIYDVFGGLLQQSVKCSNCGEISTTEQPIYDLSLHLKGRKTTDQDQNSVGQDNSID 534
S+++ +FGG L+Q + CS C + S T Q + DLS+ KG D
Sbjct: 242 RETSVVHRIFGGYLRQQILCSVCKKPSNTYQALLDLSVDAKGSSLAD------------- 288
Query: 535 NSVDQQQSSKRRFSIEKSIRDFFNPELIKRVDNKEGYTCEKCKKVTNALKSNKIIRAPET 594
S++ F + E + + NK Y CE CK++ +A K I RAP
Sbjct: 289 -----------------SLKHFVHAEKLTK-QNK--YRCENCKQLVDASKQMTIYRAPNI 328
Query: 595 LVVHLKKFRFNGTSSSKMKQAVSYPMFLDLTEYCHESISSLPVRYQLISVVVHEGRSLSS 654
L +H K+F FNG SSK+ + +SYP +L Y + S Y+LI V+VH G S S
Sbjct: 329 LTIHFKRFTFNGFQSSKISKQISYPESFNLGPYMSDPNCS--CWYELIGVLVHAGGSTRS 386
Query: 655 GHYIAHCKQPDGSWATYDDEYINKISEKQLLKEPNAYFLVYTRLTPKSVPLSSQSSNKST 714
GHY + CK +G W +DD++++ S ++L + AY L Y R + S + N T
Sbjct: 387 GHYYSFCKSSNGVWLKFDDDFVSNSSIDRVLNQ-QAYILQYKRKSTSSSKHKLNTENTVT 445
>YMR223w [O] KOG1867 Ubiquitin-specific protease
Length = 471
Score = 139 bits (350), Expect = 2e-32
Identities = 102/365 (27%), Positives = 172/365 (46%), Gaps = 67/365 (18%)
Query: 363 GLLNHGVTCYTNAAVQAMVHIPA-IQHYLFQLLRGNFKDTVKSNCVSMLL---------A 412
GL+N G TC+ ++ +Q ++H P I+H + Q+ N K C S L A
Sbjct: 138 GLINMGSTCFMSSILQCLIHNPYFIRHSMSQIHSNNCKVRSPDKCFSCALDKIVHELYGA 197
Query: 413 ETTMRMWSSDSTKNTYINPDKLINALEDINCMMSAWNQEDSHEYFMSLMSRLQEDSV--- 469
T + SS ++ N L+ IN ++ ++Q+D+HE++ +++++ + V
Sbjct: 198 LNTKQASSSSTSTNRQTGFIYLLTCAWKINQNLAGYSQQDAHEFWQFIINQIHQSYVLDL 257
Query: 470 -------PKGHKMTESIIYDVFGGLLQQSVKCSNCGEIS-TTEQPIYDLSLHLKGRKTTD 521
+K E I++ VF G L+ S+ C C S TT P DLSL +K +K
Sbjct: 258 PNAKEVSRANNKQCECIVHTVFEGSLESSIVCPGCQNNSKTTIDPFLDLSLDIKDKKKLY 317
Query: 522 QDQNSVGQDNSIDNSVDQQQSSKRRFSIEKSIRDFFNPELIKRVDNKEGYTCEKCKKVTN 581
+ +S F ++ ++DF Y C +C +
Sbjct: 318 ECLDS--------------------FHKKEQLKDF-------------NYHCGECNSTQD 344
Query: 582 ALKSNKIIRAPETLVVHLKKFR--FNGTSSSKMKQAVSYPMFLDLTEYC-------HESI 632
A+K I + P LV+ LK+F NG S+ K+ + +P +L++ YC H
Sbjct: 345 AIKQLGIHKLPSVLVLQLKRFEHLLNG-SNRKLDDFIEFPTYLNMKNYCSTKEKDKHSEN 403
Query: 633 SSLP-VRYQLISVVVHEGRSLSSGHYIAHCKQPDGSWATYDDEYINKISEKQLLKEPNAY 691
+P + Y+LI +V H+G +++ GHYIA CK G W ++D ++ IS++++LKE AY
Sbjct: 404 GKVPDIIYELIGIVSHKG-TVNEGHYIAFCKISGGQWFKFNDSMVSSISQEEVLKE-QAY 461
Query: 692 FLVYT 696
L YT
Sbjct: 462 LLFYT 466
>At3g14400 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 661
Score = 136 bits (343), Expect = 1e-31
Identities = 97/345 (28%), Positives = 160/345 (46%), Gaps = 48/345 (13%)
Query: 361 PRGLLNHGVTCYTNAAVQAMVHIPAIQHYLFQLLRGNFKDTVKSNCVSMLLAETTMRMWS 420
P GL N G TCY N+ +Q + P + + F L + K +C ++ + R S
Sbjct: 14 PLGLRNLGNTCYLNSVLQCLTFTPPLAN--FCLTHKHSSHCTKRDCPFCIVEKRIARSLS 71
Query: 421 SDSTKNTYINPDKLINALEDINCMMSAWNQEDSHEYFMSLMSRLQEDSVP------KGHK 474
D T + P+K+ + L+ QED+HE+ ++ S+ G++
Sbjct: 72 VDLTTDA---PNKISSCLKIFAEHFKLGRQEDAHEFLRYVIDACHNTSLRLKKLRYNGNE 128
Query: 475 MTE--SIIYDVFGGLLQQSVKCSNCGEISTTEQPIYDLSLHLKGRKTTDQDQNSVGQDNS 532
S++ ++FGG LQ VKC +CG S I D+SL +
Sbjct: 129 PFNGNSVVKEIFGGALQSQVKCLSCGAESNKADEIMDISLEIL----------------- 171
Query: 533 IDNSVDQQQSSKRRFSIEKSIRDFFNPELIKRVDNKEGYTCEKCKKVTNALKSNKIIRAP 592
QSS S+++S++ FF E++ D Y CE C+K+ A K I++AP
Sbjct: 172 --------QSS----SVKESLQKFFQSEIL---DGNNKYRCESCEKLVTARKQMSILQAP 216
Query: 593 ETLVVHLKKFRFNGTSSSKMKQAVSYPMFLDLTEYCHESISSLPVRYQLISVVVHEGRSL 652
LV+ LK RF G K+ +A+S+ L L+ + ++ Y+L ++VH G S
Sbjct: 217 NILVIQLK--RFGGIFGGKIDKAISFGEILVLSNFMSKASKDPQPEYKLFGIIVHSGFSP 274
Query: 653 SSGHYIAHCKQPDGSWATYDDEYINKISEKQLLKEPNAYFLVYTR 697
SGHY A+ K G W +D +++ + +++L E AY L ++R
Sbjct: 275 ESGHYYAYVKDSLGRWYCCNDSFVSLSTLQEVLSE-KAYILFFSR 318
>Hs20540195 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 823
Score = 132 bits (332), Expect = 2e-30
Identities = 94/342 (27%), Positives = 155/342 (44%), Gaps = 49/342 (14%)
Query: 363 GLLNHGVTCYTNAAVQAMVHIPAIQHYLFQLLRGNFKDTVKSNCVSMLLAETTMRMWSSD 422
GL N G TC+ NAA+Q + + P + +Y+ L T + M+ TM+ +
Sbjct: 112 GLQNLGNTCFANAALQCLTYTPPLANYM---LSHEHSKTCHAEGFCMMC---TMQAHITQ 165
Query: 423 STKNT--YINPDKLINALEDINCMMSAWNQEDSHEYFMSLMSRLQEDSVPKGHKMTE--- 477
+ N I P +IN + I NQED+HE+ + +Q+ + +K+
Sbjct: 166 ALSNPGDVIKPMFVINEMRRIARHFRFGNQEDAHEFLQYTVDAMQKACLNGSNKLDRHTQ 225
Query: 478 --SIIYDVFGGLLQQSVKCSNCGEISTTEQPIYDLSLHLKGRKTTDQDQNSVGQDNSIDN 535
+++ +FGG L+ VKC NC +S T P D++L +K +
Sbjct: 226 ATTLVCQIFGGYLRSRVKCLNCKGVSDTFDPYLDITLEIKAAQ----------------- 268
Query: 536 SVDQQQSSKRRFSIEKSIRDFFNPELIKRVDNKEGYTCEKCKKVTNALKSNKIIRAPETL 595
S+ K++ F PE ++D + Y C KCKK+ A K I R+ L
Sbjct: 269 ------------SVNKALEQFVKPE---QLDGENSYKCSKCKKMVPASKRFTIHRSSNVL 313
Query: 596 VVHLKKFRFNGTSSSKMKQAVSYPMFLDLTEYCHESISSLPVRYQLISVVVHEGRSLSSG 655
+ LK RF + K+ + V YP +LD+ Y + + P+ Y L +V+VH G + +G
Sbjct: 314 TLSLK--RFANFTGGKIAKDVKYPEYLDIRPYMSQP-NGEPIVYVLYAVLVHTGFNCHAG 370
Query: 656 HYIAHCKQPDGSWATYDDEYINKISEKQLLKEPNAYFLVYTR 697
HY + K +G W +D ++ + +L + AY L Y R
Sbjct: 371 HYFCYIKASNGLWYQMNDSIVSTSDIRSVLSQ-QAYVLFYIR 411
>7295432 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 577
Score = 129 bits (324), Expect = 2e-29
Identities = 93/347 (26%), Positives = 164/347 (46%), Gaps = 56/347 (16%)
Query: 363 GLLNHGVTCYTNAAVQAMVHIPAIQHYLFQ----LLRGNFKDTVKSNCVSMLLAETTMRM 418
G++N G TCY N+ +QA++HIPA+ ++L L N + S C+ + +T +
Sbjct: 173 GMINVGNTCYLNSTLQALLHIPALANWLVSEQAHLADCNVAEP-GSGCIICAMTKTLLAT 231
Query: 419 WSSDSTKNTYINPDKLINALEDINCMMSAWNQEDSHEYFMSLMSRLQEDSVPK--GHKMT 476
S+ S + P + + L+ I M QED+HE+ L+ ++ + + +K
Sbjct: 232 QSNQSA----VRPFLIYSKLKQICKHMVVGRQEDAHEFLRFLVEAMERAYLMRFRNYKEL 287
Query: 477 ESIIYD------VFGGLLQQSVKCSNCGEISTTEQPIYDLSLHLKGRKTTDQDQNSVGQD 530
+ ++ + +FGG L+ V+C +C +S T Q DL L ++
Sbjct: 288 DQLVKETTPLGQIFGGYLRSEVRCLSCNHVSITFQHFQDLLLDIR--------------- 332
Query: 531 NSIDNSVDQQQSSKRRFSIEKSIRDFFNPELIKRVDNKEGYTCEKCKKVTNALKSNKIIR 590
+ S+E + F+ E ++ + GY CE CKK +A K + R
Sbjct: 333 --------------KADSLEDAFEGHFSRERLEDM----GYKCEGCKKKVSATKQFSLER 374
Query: 591 APETLVVHLKKFRFNGTSSSKMKQAVSYPMFLDLTEYC--HESISSLPVRYQLISVVVHE 648
AP TL + LK+F G +K+ + +S+ +DL++Y ++ + P+ Y+L+S+V H
Sbjct: 375 APITLCIQLKRFSMIG---NKLTKQISFKSRIDLSKYAARSQAAQAQPLTYRLVSMVTHL 431
Query: 649 GRSLSSGHYIAHCKQPDGSWATYDDEYINKISEKQLLKEPNAYFLVY 695
G S GHY A GS+ +DD Y+ I+ + NAY + +
Sbjct: 432 GASQHCGHYTAIGSTDTGSFYNFDDSYVRPIAMHSVC-NTNAYIMFF 477
>At5g10790 [O] KOG1867 Ubiquitin-specific protease
Length = 557
Score = 122 bits (307), Expect = 2e-27
Identities = 98/373 (26%), Positives = 167/373 (44%), Gaps = 52/373 (13%)
Query: 362 RGLLNHGVTCYTNAAVQAMVHIPAIQHYLFQLLRGNFKDTVKSNCVSMLLAETTM----- 416
RGL N G TC+ NA +QA+VH P +++ F L + +D + +L +
Sbjct: 177 RGLNNLGSTCFMNAVLQALVHAPPLRN--FWLSGQHNRDLCPRRTMGLLCLPCDLDVIFS 234
Query: 417 RMWSSDSTKNTYINPDKLINALEDINCMMSAWNQEDSHEYFMSLMSRLQEDS-----VPK 471
M+S D T +P L+ + + ++ + Q+DSHE+F+SL+ R+ E+ + +
Sbjct: 235 AMFSGDRTP---YSPAHLLYSWWQHSTNLATYEQQDSHEFFISLLDRIHENEGKSKCLYQ 291
Query: 472 GHKMTESIIYDVFGGLLQQSVKCSNCGEISTTEQPIYDLSLHLKGRKTTDQDQNSVGQDN 531
++ + I + F GLL+ V C+ CG STT P D+SL L N +
Sbjct: 292 DNEECQCITHKAFSGLLRSDVTCTTCGSTSTTYDPFIDISLTL-------DSMNGFSPAD 344
Query: 532 SIDNSVDQQQSSKRRFSIEKSIRDFFNPELIKRVDNKEGYTCEKCKKVTNALKSNKIIRA 591
N S DFF +++ + C+ C + + K I R
Sbjct: 345 CRKNRYSGGPSVNAIMPTLSGCLDFFTRS--EKLGPDQKLNCQSCGEKRESSKQMSIRRL 402
Query: 592 PETLVVHLKKFRFNGT--SSSKMKQAVSYPMFLDLTEYCHESI----------------- 632
P L +H+K+F + T +S K+ + YP L+++ Y SI
Sbjct: 403 PLLLCLHVKRFEHSLTRKTSRKIDSYLQYPFRLNMSPYLSSSIIGKRFGNRIFAFDGEGE 462
Query: 633 ------SSLPVRYQLISVVVHEGRSLSSGHYIAHCKQPDGSWATYDDEYINKISEKQLLK 686
SS +++ +VV H+G L SGHY+ + + G W DD +IN++ E+++++
Sbjct: 463 YDSSSSSSPSAEFEIFAVVTHKG-MLESGHYVTYLRL-KGLWYRCDDAWINEV-EEEVVR 519
Query: 687 EPNAYFLVYTRLT 699
Y L Y + T
Sbjct: 520 GCECYMLFYAQET 532
>Hs13435157 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 548
Score = 121 bits (304), Expect = 3e-27
Identities = 90/342 (26%), Positives = 157/342 (45%), Gaps = 47/342 (13%)
Query: 363 GLLNHGVTCYTNAAVQAMVHIPAIQHYLFQLLRGNFKDTVKSN-CVSMLLAETTMRMWSS 421
GL N G TC+ NA +Q + + P + +YL L + + + + + C+ ++ ++ +++
Sbjct: 123 GLHNLGNTCFLNATIQCLTYTPPLANYL--LSKEHARSCHQGSFCMLCVMQNHIVQAFAN 180
Query: 422 DSTKNTYINPDKLINALEDINCMMSAWNQEDSHEYFMSLMSRLQE---DSVPKGHKMTES 478
I P I L+ I NQED+HE+ + +Q+ + K + T++
Sbjct: 181 SGNA---IKPVSFIRDLKKIARHFRFGNQEDAHEFLRYTIDAMQKACLNGCAKLDRQTQA 237
Query: 479 --IIYDVFGGLLQQSVKCSNCGEISTTEQPIYDLSLHLKGRKTTDQDQNSVGQDNSIDNS 536
+++ +FGG L+ VKCS C +S T P D++L ++
Sbjct: 238 TTLVHQIFGGYLRSRVKCSVCKSVSDTYDPYLDVALEIR--------------------- 276
Query: 537 VDQQQSSKRRFSIEKSIRDFFNPELIKRVDNKEGYTCEKCKKVTNALKSNKIIRAPETLV 596
+ +I +++ F +++ + Y C KCKK A K I R L
Sbjct: 277 --------QAANIVRALELFVKADVLS---GENAYMCAKCKKKVPASKRFTIHRTSNVLT 325
Query: 597 VHLKKFRFNGTSSSKMKQAVSYPMFLDLTEYCHESISSLPVRYQLISVVVHEGRSLSSGH 656
+ LK RF S K+ + V YP FL++ Y ++ PV Y L +V+VH G S +GH
Sbjct: 326 LSLK--RFANFSGGKITKDVGYPEFLNIRPYMSQNNGD-PVMYGLYAVLVHSGYSCHAGH 382
Query: 657 YIAHCKQPDGSWATYDDEYINKISEKQLLKEPNAYFLVYTRL 698
Y + K +G W +D ++ + K +L + AY L Y R+
Sbjct: 383 YYCYVKASNGQWYQMNDSLVHSSNVKVVLNQ-QAYVLFYLRI 423
>At1g17110 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 891
Score = 121 bits (304), Expect = 3e-27
Identities = 96/367 (26%), Positives = 164/367 (44%), Gaps = 52/367 (14%)
Query: 346 QRIVKNWGSKLTQLKPRGLLNHGVTCYTNAAVQAMVHIPAIQHYLFQLLRGNFKD-TVKS 404
+ +K + ++ L PRGL+N G +CY NA +Q++ + YL L R + + + K
Sbjct: 389 EEFLKFFQCEVFDLSPRGLVNCGNSCYANAVLQSLTCTKPLVAYL--LRRSHSRSCSGKD 446
Query: 405 NCVSMLLAETTMRMWSSDSTKNTYINPDKLINALEDINCMMSAWNQEDSHEYFMSLMSRL 464
C+ L + M + S ++ ++++ + INC + +QED+HE+ L++ +
Sbjct: 447 WCLMCELEQHVMMLRESGGP----LSASRILSHMRSINCQIGDGSQEDAHEFLRLLVASM 502
Query: 465 QEDSVPKGHKMTE--------SIIYDVFGGLLQQSVKCSNCGEISTTEQPIYDLSLHLKG 516
Q + + T+ +++ +FGG L+ VKC C S + I DL+L + G
Sbjct: 503 QSICLERLGGETKVDPRLQETTLVQHMFGGRLRSKVKCLRCDHESERYENIMDLTLEIYG 562
Query: 517 RKTTDQDQNSVGQDNSIDNSVDQQQSSKRRFSIEKSIRDFFNPELIKRVDNKEGYTCEKC 576
+ QD ++ F PE +D + Y C +C
Sbjct: 563 WVESLQD----------------------------ALTQFTRPE---DLDGENMYRCSRC 591
Query: 577 KKVTNALKSNKIIRAPETLVVHLKKFRFNGTSSSKMKQAVSYPMFLDLTEYCHESISSLP 636
A K I AP L + LK RF K+ + +S+P LD+ + + +P
Sbjct: 592 AGYVRARKELSIHEAPNILTIVLK--RFQEGRYGKINKCISFPEMLDMIPFMTRT-GDVP 648
Query: 637 VRYQLISVVVHEG--RSLSSGHYIAHCKQPDGSWATYDDEYINKISEKQLLKEPNAYFLV 694
Y L +V+VH + SGHYI++ K G+W DD I+ + Q++ E AY L
Sbjct: 649 PLYMLYAVIVHLDTLNASFSGHYISYVKDLRGNWYRIDDSEIHPVPMTQVMSE-GAYMLF 707
Query: 695 YTRLTPK 701
Y R P+
Sbjct: 708 YMRSYPR 714
>Hs22055583 [O] KOG1867 Ubiquitin-specific protease
Length = 800
Score = 119 bits (297), Expect = 2e-26
Identities = 94/354 (26%), Positives = 152/354 (42%), Gaps = 33/354 (9%)
Query: 362 RGLLNHGVTCYTNAAVQAMVHIPAIQHYLFQLLRGNFKDTVKSNCVSMLLAETTMRMWSS 421
RGL+N G TC+ N VQA+ HIP ++ + F + T S C+ ++ M+S
Sbjct: 452 RGLINLGNTCFMNCIVQALTHIPLLKDF-FLSDKHKCIMTSPSLCLVCEMSSLFHAMYSG 510
Query: 422 DSTKNTYINPDKLINALEDINCMMSAWNQEDSHEYFMSLMSRLQEDSVP-------KGHK 474
T + P KL++ + ++ + Q+D+HE+ ++++ L S
Sbjct: 511 SRTPHI---PYKLLHLIWIHAEHLAGYRQQDAHEFLIAILDVLHRHSKDDSGGQEANNPN 567
Query: 475 MTESIIYDVFGGLLQQSVKCSNCGEISTTEQPIYDLSLHLKGRKTTDQDQNSVGQDNSID 534
II +F G LQ V C C +STT P +D+SL L G T QN D
Sbjct: 568 CCNCIIDQIFTGGLQSDVTCQACHSVSTTIDPCWDISLDLPGSCATFDSQN----PERAD 623
Query: 535 NSVDQQQSSKRRFSIEKSIRDFFNPELIKRVDNKEGYTCEKCKKVTNALKSNKIIRAPET 594
++V + S+ ++ F PE + + C C+ + K + + P
Sbjct: 624 STVSRDDHIPGIPSLTDCLQWFTRPE---HLGSSAKIKCNSCQSYQESTKQLTMKKLPIV 680
Query: 595 LVVHLKKFRFNGTSSSKMKQAVSYPMFLDLTEYCHESISSL-------------PVRYQL 641
HLK+F G K+ +S+P+ LD+T + + S +Y L
Sbjct: 681 ACFHLKRFEHVGKQRRKINTFISFPLELDMTPFLASTKESRMKEGQPPTDCVPNENKYSL 740
Query: 642 ISVVVHEGRSLSSGHYIAHCKQPDGSWATYDDEYINKISEKQLLKEPNAYFLVY 695
+V+ H G +L SGHY + +Q W + DD I K + + LL Y L Y
Sbjct: 741 FAVINHHG-TLESGHYTSFIRQQKDQWFSCDDAIITKATIEDLLYS-EGYLLFY 792
>CE11978 [O] KOG1870 Ubiquitin C-terminal hydrolase
Length = 555
Score = 117 bits (293), Expect = 6e-26
Identities = 91/339 (26%), Positives = 151/339 (43%), Gaps = 61/339 (17%)
Query: 363 GLLNHGVTCYTNAAVQAMVHIPAIQHYLFQLLR----GNFKDTVKSNCVSMLLAETTMRM 418
G LN G TCY NA +Q + H YL +L+ N + + M L +R
Sbjct: 183 GYLNFGNTCYMNAVLQLLGHCSPFTQYLIELIPPGGWSNCSHDIPKTAIQMAL---DLRN 239
Query: 419 WSSDSTKNTYINPDKLINALEDINCMMSAWNQEDSHEYFMSLMSRLQED----------- 467
SD Y++P K+I Q+D+ E+ +L+ L D
Sbjct: 240 MYSDFPL-PYLSPWKIIT-------------QQDASEFMRNLLDILDRDLKTCSEYHRTN 285
Query: 468 ------------SVPKGHKMTESIIYDVFGGLLQQSVKCSNCGEISTTEQPIYDLSLHLK 515
++ T++ I +F G+L+ ++C +CG S T + DLS+ +
Sbjct: 286 TLIEMGNPEMDYAIAMNAPHTKTAISAIFQGVLENQIQCHSCGFRSRTIENFLDLSIPIV 345
Query: 516 GRKTTDQDQNSVGQD--------NSIDNSVDQ----QQSSKRRFSIEKSIRDFFNPELIK 563
G ++ S D ++I++ D Q + + S+E + FF ++
Sbjct: 346 GENEFEEMYASKKLDTPKAPCTSSNIEDGQDPGFLVHQGAFNKTSLESCLDRFFQNSTLQ 405
Query: 564 RVDNKEGYTCEKCKKVTNALKSNKIIRAPETLVVHLKKFRFNGTSSSKMKQAVSYPMFLD 623
DN+ Y+C KC+ + +A KS K R PE +++ LK+FR S K+ + V +P L
Sbjct: 406 D-DNQ--YSCSKCEVLVDATKSTKAHRLPEVIIIQLKRFRHTMFGSCKVGKVVEFP--LR 460
Query: 624 LTEYCHESISSLPVRYQLISVVVHEGRSLSSGHYIAHCK 662
++ + S P Y L+ VVHEGRSL GHY+++C+
Sbjct: 461 SQDFGRWTTSGEPALYDLVGFVVHEGRSLEFGHYVSYCR 499
>At3g49600_2 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase
Length = 1035
Score = 116 bits (291), Expect = 1e-25
Identities = 89/361 (24%), Positives = 166/361 (45%), Gaps = 60/361 (16%)
Query: 361 PRGLLNHGVTCYTNAAVQAMVHIPAIQHYLFQLLRGNFKDTVKSNCVSMLLAETTMRMWS 420
P GL N G TCY N+ +Q + A + +F + K + ++ L A+
Sbjct: 73 PAGLTNLGATCYANSILQCLYMNTAFREGVFSVEVHVLKQNPVLDQIARLFAQL------ 126
Query: 421 SDSTKNTYINPDKLINALEDINCMMSAWNQEDSHEYFMSLMSRLQEDSVPKGHKMTESII 480
+++ ++++ D + LE N + Q+D+HE+ L+S L+ + G K ++I+
Sbjct: 127 -HASQKSFVDSDAFVKTLELDNGV-----QQDTHEFLTLLLSLLERCLLHSGVK-AKTIV 179
Query: 481 YDVFGGLLQQSVKCSNCG---EISTTEQPIYDLSLHLKGRKTTDQDQNSVGQDNSIDNSV 537
D+F G + CS CG E S+ + Y L L++KG K
Sbjct: 180 QDLFSGSVSHVTTCSKCGRDSEASSKMEDFYALELNVKGLK------------------- 220
Query: 538 DQQQSSKRRFSIEKSIRDFFNPELIKRVDNKEGYTCEKCKKVTNALKSNKIIRAPETLVV 597
S++ S+ D+ + +++++ Y C C +A + K+ P +
Sbjct: 221 ----------SLDASLNDYLS---LEQLNGDNQYFCGSCNARVDATRCIKLRTLPPVITF 267
Query: 598 HLKKFRF--NGTSSSKMKQAVSYPMFLDLTEYCHESISSLPVRYQLISVVVHEGRSLSSG 655
LK+ F T+ K+ + S+P LD+ ES S + Y L +V++H+G +++SG
Sbjct: 268 QLKRCIFLPKTTAKKKITSSFSFPQVLDMGSRLAES-SQNKLTYDLSAVLIHKGSAVNSG 326
Query: 656 HYIAHCK-QPDGSWATYDDEYINKISEKQLLKEPNAYFLVYTRLTPKSVPLSSQSSNKST 714
HY+AH K + G W +DDE+++++ ++ + ++ TP+S + SS T
Sbjct: 327 HYVAHIKDEKTGLWWEFDDEHVSELGKRPCNEASSS--------TPQSESNGTASSGNIT 378
Query: 715 D 715
D
Sbjct: 379 D 379
>At4g31670 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 631
Score = 116 bits (290), Expect = 1e-25
Identities = 98/363 (26%), Positives = 161/363 (43%), Gaps = 54/363 (14%)
Query: 351 NWGSKLTQLKPRGLLNHGVTCYTNAAVQAMVHIPAIQHYLFQLLRGNFKDTVKSNCVSML 410
NW + +L P GL+N G +C+ N +Q + + YL + +G+ ++ ++++ +
Sbjct: 159 NWDNP--ELAPCGLMNCGNSCFANVILQCLSWTRPLVAYLLE--KGHKRECMRNDWCFLC 214
Query: 411 LAETTMRMWSSDSTKNTYINPDKLINALEDINCMMSAWNQEDSHEYFMSLMSRLQ----- 465
+T + S +P +I+ L +I + QED+HE+ + +Q
Sbjct: 215 EFQTHVERASQSRFP---FSPMNIISRLTNIGGTLGYGRQEDAHEFMRYAIDMMQSVCLD 271
Query: 466 ----EDSVPKGHKMTESIIYDVFGGLLQQSVKCSNCGEISTTEQPIYDLSLHLKGRKTTD 521
E VP + T I Y +FGGLLQ V+C+ C +S + + DL + +
Sbjct: 272 EFGGEKIVPPRSQETTLIQY-IFGGLLQSQVQCTVCNHVSDQYENMMDLIVEMH------ 324
Query: 522 QDQNSVGQDNSIDNSVDQQQSSKRRFSIEKSIRDFFNPELIKRVDNKEGYTCEKCKKVTN 581
G S++ +DQ F E DN Y C++C
Sbjct: 325 ------GDAGSLEECLDQ-----------------FTAEEWLHGDNM--YKCDRCSDYVK 359
Query: 582 ALKSNKIIRAPETLVVHLKKFRFNGTSSSKMKQAVSYPMFLDLTEYCHESISSLPVRYQL 641
A K I RAP L + LK R+ G K+ + +S+P LDL Y E V Y+L
Sbjct: 360 ACKRLTIRRAPNILTIALK--RYQGGRYGKLNKRISFPETLDLNPYMSEGGDGSDV-YKL 416
Query: 642 ISVVVHEGRSLSS--GHYIAHCKQPDGSWATYDDEYINKISEKQLLKEPNAYFLVYTRLT 699
+V+VH +S GHYI + K G+W DD I + + +L + AY L+Y+R+
Sbjct: 417 YAVIVHLDMLNASFFGHYICYIKDFCGNWYRIDDSEIESVELEDVLSQ-RAYMLLYSRIQ 475
Query: 700 PKS 702
+S
Sbjct: 476 ARS 478
>Hs22044543 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 530
Score = 115 bits (289), Expect = 2e-25
Identities = 83/339 (24%), Positives = 150/339 (43%), Gaps = 53/339 (15%)
Query: 363 GLLNHGVTCYTNAAVQAMVHIPAIQHYLFQLLRGNFKDTVKSNCVSMLLAETTMRMWSSD 422
GL N G TCY NA++Q + + P + +Y+ K + + A T +
Sbjct: 81 GLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALH--- 137
Query: 423 STKNTYINPDKLINALEDINCMMSAWNQEDSHEYFMSLMSRLQEDSVPKGHKMTE----- 477
NP +I + + QED+HE+ M + +++ +P GHK +
Sbjct: 138 -------NPGHVIQPSQALAAGFHRGKQEDAHEFLMFTVDAMKKACLP-GHKQVDHHSKD 189
Query: 478 -SIIYDVFGGLLQQSVKCSNCGEISTTEQPIYDLSLHLKGRKTTDQDQNSVGQDNSIDNS 536
++I+ +FGG + +KC +C IS T P D++L ++ +
Sbjct: 190 TTLIHQIFGGYWRSQIKCLHCHRISDTFDPYLDIALDIQAAQ------------------ 231
Query: 537 VDQQQSSKRRFSIEKSIRDFFNPELIKRVDNKEGYTCEKCKKVTNALKSNKIIRAPETLV 596
S+++++ PE ++ + Y C C + A K+ + + + L+
Sbjct: 232 -----------SVQQALEQLVKPE---ELNGENAYHCGVCLQRAPASKTLTLHTSAKVLI 277
Query: 597 VHLKKFRFNGTSSSKMKQAVSYPMFLDLTEYCHESISSLPVRYQLISVVVHEGRSLSSGH 656
+ LK RF+ + +K+ + V YP LD+ Y + ++ P+ Y L +V+VH G S +GH
Sbjct: 278 LVLK--RFSDVTGNKIAKNVQYPECLDMQPYMSQQ-NTGPLVYVLYAVLVHAGWSCHNGH 334
Query: 657 YIAHCKQPDGSWATYDDEYINKISEKQLLKEPNAYFLVY 695
Y ++ K +G W DD + S +L + AY L Y
Sbjct: 335 YFSYVKAQEGQWYKMDDAEVTASSITSVLTQ-QAYVLFY 372
>Hs22044547 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 530
Score = 115 bits (288), Expect = 2e-25
Identities = 83/339 (24%), Positives = 150/339 (43%), Gaps = 53/339 (15%)
Query: 363 GLLNHGVTCYTNAAVQAMVHIPAIQHYLFQLLRGNFKDTVKSNCVSMLLAETTMRMWSSD 422
GL N G TCY NA++Q + + P++ +Y+ K + + A T +
Sbjct: 81 GLQNMGNTCYVNASLQCLTYTPSLANYMLSREHSQTCHRHKGCMLCTMQAHITRALH--- 137
Query: 423 STKNTYINPDKLINALEDINCMMSAWNQEDSHEYFMSLMSRLQEDSVPKGHKMTE----- 477
NP +I + + QED+HE+ M + +++ +P GHK +
Sbjct: 138 -------NPGHVIQPSQALAAGFHRGKQEDAHEFLMFTVDAMKKACLP-GHKQVDHHSKD 189
Query: 478 -SIIYDVFGGLLQQSVKCSNCGEISTTEQPIYDLSLHLKGRKTTDQDQNSVGQDNSIDNS 536
++I+ +FGG + +KC +C IS T P D++L ++ +
Sbjct: 190 TTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQ------------------ 231
Query: 537 VDQQQSSKRRFSIEKSIRDFFNPELIKRVDNKEGYTCEKCKKVTNALKSNKIIRAPETLV 596
S+++++ PE ++ + Y C C + A K+ + + + L+
Sbjct: 232 -----------SVQQALEQLVKPE---ELNGENAYHCGVCLQRAPASKTLTLHTSAKVLI 277
Query: 597 VHLKKFRFNGTSSSKMKQAVSYPMFLDLTEYCHESISSLPVRYQLISVVVHEGRSLSSGH 656
+ LK RF+ + +K+ + V YP LD+ Y + + P+ Y L +V+VH G S +GH
Sbjct: 278 LVLK--RFSDVTGNKIAKNVQYPECLDMQPYMSQQNTG-PLVYVLYAVLVHAGWSCYNGH 334
Query: 657 YIAHCKQPDGSWATYDDEYINKISEKQLLKEPNAYFLVY 695
Y ++ K +G W DD + S +L + AY L Y
Sbjct: 335 YFSYVKAQEGQWYKMDDAEVTASSITSVLTQ-QAYVLFY 372
>Hs22044530 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 565
Score = 115 bits (288), Expect = 2e-25
Identities = 83/339 (24%), Positives = 149/339 (43%), Gaps = 53/339 (15%)
Query: 363 GLLNHGVTCYTNAAVQAMVHIPAIQHYLFQLLRGNFKDTVKSNCVSMLLAETTMRMWSSD 422
GL N G TCY NA++Q + + P + +Y+ K + + A T +
Sbjct: 116 GLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALH--- 172
Query: 423 STKNTYINPDKLINALEDINCMMSAWNQEDSHEYFMSLMSRLQEDSVPKGHKMTE----- 477
NP +I + + QED+HE+ M + +++ +P GHK +
Sbjct: 173 -------NPGHVIQPSQALAAGFHRGKQEDAHEFLMFTVDAMKKACLP-GHKQVDHHSKD 224
Query: 478 -SIIYDVFGGLLQQSVKCSNCGEISTTEQPIYDLSLHLKGRKTTDQDQNSVGQDNSIDNS 536
++I+ +FGG + +KC +C IS T P D++L ++ +
Sbjct: 225 TTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQ------------------ 266
Query: 537 VDQQQSSKRRFSIEKSIRDFFNPELIKRVDNKEGYTCEKCKKVTNALKSNKIIRAPETLV 596
S+++++ PE ++ + Y C C + A K+ + + + L+
Sbjct: 267 -----------SVQQALEQLVKPE---ELNGENAYHCGVCLQRAPASKTLTLHTSAKVLI 312
Query: 597 VHLKKFRFNGTSSSKMKQAVSYPMFLDLTEYCHESISSLPVRYQLISVVVHEGRSLSSGH 656
+ LK RF+ + +K+ + V YP LD+ Y + + P+ Y L +V+VH G S +GH
Sbjct: 313 LVLK--RFSDVTGNKIAKNVQYPECLDMQPYMSQQNTG-PLVYVLYAVLVHAGWSCYNGH 369
Query: 657 YIAHCKQPDGSWATYDDEYINKISEKQLLKEPNAYFLVY 695
Y ++ K +G W DD + S +L + AY L Y
Sbjct: 370 YFSYVKAQEGQWYKMDDAEVTAASITSVLSQ-QAYVLFY 407
>At5g65450 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 731
Score = 115 bits (288), Expect = 2e-25
Identities = 96/365 (26%), Positives = 158/365 (42%), Gaps = 52/365 (14%)
Query: 358 QLKPRGLLNHGVTCYTNAAVQAMVHIPAIQHYLFQLLRGNFKDTV--KSNCVSMLLAETT 415
+L+P GL+N G +CY NA +Q + + YL +RG T KS C
Sbjct: 325 ELQPFGLVNLGNSCYANAVLQCLAFTRPLISYL---IRGLHSKTCRKKSWCFVCEFEHLI 381
Query: 416 MRMWSSDSTKNTYINPDKLINALEDINCMMSAWNQEDSHEYFMSLMSRLQE---DSVPKG 472
++ +S ++P K+++ L+ I + +ED+HE+ + +Q P
Sbjct: 382 LKARGGESP----LSPIKILSKLQKIGKHLGPGKEEDAHEFLRCAVDTMQSVFLKEAPAA 437
Query: 473 HKMTE--SIIYDVFGGLLQQSVKCSNCGEISTTEQPIYDLSLHLKGRKTTDQDQNSVGQD 530
E +++ FGG L +KC C S + + DL++ + G +G
Sbjct: 438 GPFAEETTLVGLTFGGYLHSKIKCMACLHKSERPELMMDLTVEIDG---------DIG-- 486
Query: 531 NSIDNSVDQQQSSKRRFSIEKSIRDFFNPELIKRVDNKEGYTCEKCKKVTNALKSNKIIR 590
S+E+++ F E++ D + Y C +CK A K I+
Sbjct: 487 -----------------SLEEALAQFTAYEVL---DGENRYFCGRCKSYQKAKKKLMILE 526
Query: 591 APETLVVHLKKFRFNGTSSSKMKQAVSYPMFLDLTEYCHESISSLPVRYQLISVVVH--E 648
P L V LK RF + K+ + + +P LD++ Y + Y L +VVVH
Sbjct: 527 GPNILTVVLK--RFQSDNFGKLSKPIHFPELLDISPYMSDPNHGDHPVYSLYAVVVHLDA 584
Query: 649 GRSLSSGHYIAHCKQPDGSWATYDDEYINKISEKQLLKEPNAYFLVYTRLTPKSVPLSSQ 708
+L SGHY+ + K DG W DD + + + +L E AY L+Y R +P+ P+S
Sbjct: 585 MSTLFSGHYVCYIKTLDGDWFKIDDSNVFPVQLETVLLE-GAYMLLYARDSPR--PVSKN 641
Query: 709 SSNKS 713
KS
Sbjct: 642 GGRKS 646
>Hs5730108 [O] KOG1870 Ubiquitin C-terminal hydrolase
Length = 913
Score = 115 bits (287), Expect = 3e-25
Identities = 81/275 (29%), Positives = 135/275 (48%), Gaps = 32/275 (11%)
Query: 456 YFMSLMSRLQEDSVPKGHKMTESIIYDVFGGLLQQSVKCSNCGEISTTEQPIYDLSLHLK 515
Y + L S + + S+I D+F G + V+C C +STT + DLSL +
Sbjct: 420 YVLKKAQVLSAGSRRRKEQRYRSVISDIFDGSILSLVQCLTCDRVSTTVETFQDLSLPIP 479
Query: 516 GRKTTDQ-----DQNSVGQDNSIDNSVDQQ------QSSKRRF--------------SIE 550
G++ + QN + + +S Q RRF ++E
Sbjct: 480 GKEDLAKLHSAIYQNVPAKPGACGDSYAAQGWLAFIVEYIRRFVVSCTPSWFWGPVVTLE 539
Query: 551 KSIRDFFNPELIKRVDNKEGYTCEKCKKVTNALKSNKIIRAPETLVVHLKKFRFNGTSSS 610
+ FF + +K DN Y+CE+CKK+ N +K K++R PE L +HLK+FR S
Sbjct: 540 DCLAAFFAADELKG-DNM--YSCERCKKLRNGVKYCKVLRLPEILCIHLKRFRHEVMYSF 596
Query: 611 KMKQAVSYPM-FLDLTEYCHESISSLPVRYQLISVVVHEGRSLSSGHYIAHCKQP-DGSW 668
K+ VS+P+ LDL + + +S Y L+SV+ H G + SGHYIA+C+ +G W
Sbjct: 597 KINSHVSFPLEGLDLRPFLAKECTSQITTYDLLSVICHHG-TAGSGHYIAYCQNVINGQW 655
Query: 669 ATYDDEYINKISEKQLLKEPNAYFLVYTRLTPKSV 703
+DD+Y+ ++ E +++ Y L Y + + +++
Sbjct: 656 YEFDDQYVTEVHE-TVVQNAEGYVLFYRKSSEEAM 689
Score = 52.8 bits (125), Expect = 2e-06
Identities = 32/112 (28%), Positives = 55/112 (48%), Gaps = 7/112 (6%)
Query: 359 LKPRGLL---NHGVTCYTNAAVQAMVHIPAIQHYLFQLLRGNFKDTVKSNCVSMLLAETT 415
LKPRGL N G +CY NAA+QA+ + P + + + G T K + +
Sbjct: 139 LKPRGLTGMKNLGNSCYMNAALQALSNCPPLTQFFLEC--GGLVRTDKKPALCKSYQKLV 196
Query: 416 MRMWSSDSTKNTYINPDKLINALEDINCMMSAWNQEDSHEYFMSLMSRLQED 467
+W + +Y+ P L + ++ +N M + Q+D+ E+ LM +L E+
Sbjct: 197 SEVWHKK--RPSYVVPTSLSHGIKLVNPMFRGYAQQDTQEFLRCLMDQLHEE 246
>Hs22044565 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 398
Score = 115 bits (287), Expect = 3e-25
Identities = 83/339 (24%), Positives = 149/339 (43%), Gaps = 53/339 (15%)
Query: 363 GLLNHGVTCYTNAAVQAMVHIPAIQHYLFQLLRGNFKDTVKSNCVSMLLAETTMRMWSSD 422
GL N G TCY NA++Q + + P + +Y+ K + + A T +
Sbjct: 81 GLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCAMQAHITRALH--- 137
Query: 423 STKNTYINPDKLINALEDINCMMSAWNQEDSHEYFMSLMSRLQEDSVPKGHKMTE----- 477
NP +I + + QED+HE+ M + +++ +P GHK +
Sbjct: 138 -------NPGHVIQPSQALAAGFHRGKQEDAHEFLMFTVDAMKKACLP-GHKQVDHHSKD 189
Query: 478 -SIIYDVFGGLLQQSVKCSNCGEISTTEQPIYDLSLHLKGRKTTDQDQNSVGQDNSIDNS 536
++I+ +FGG + +KC +C IS T P D++L ++ +
Sbjct: 190 TTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQ------------------ 231
Query: 537 VDQQQSSKRRFSIEKSIRDFFNPELIKRVDNKEGYTCEKCKKVTNALKSNKIIRAPETLV 596
S+++++ PE ++ + Y C C + A K+ + + + L+
Sbjct: 232 -----------SVQQALEQLVKPE---ELNGENAYHCGVCLQRAPASKTLALHTSAKVLI 277
Query: 597 VHLKKFRFNGTSSSKMKQAVSYPMFLDLTEYCHESISSLPVRYQLISVVVHEGRSLSSGH 656
+ LK RF+ + +K+ + V YP LD+ Y + + P+ Y L +V+VH G S +GH
Sbjct: 278 LVLK--RFSDVTGNKIAKNVQYPECLDMQPYMSQQNTG-PLVYVLYAVLVHAGWSCHNGH 334
Query: 657 YIAHCKQPDGSWATYDDEYINKISEKQLLKEPNAYFLVY 695
Y ++ K +G W DD + S +L + AY L Y
Sbjct: 335 YFSYVKAQEGQWYKIDDAEVTASSITSVLTQ-QAYVLFY 372
>Hs22044559 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 530
Score = 115 bits (287), Expect = 3e-25
Identities = 83/339 (24%), Positives = 149/339 (43%), Gaps = 53/339 (15%)
Query: 363 GLLNHGVTCYTNAAVQAMVHIPAIQHYLFQLLRGNFKDTVKSNCVSMLLAETTMRMWSSD 422
GL N G TCY NA++Q + + P + +Y+ K + + A T +
Sbjct: 81 GLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALH--- 137
Query: 423 STKNTYINPDKLINALEDINCMMSAWNQEDSHEYFMSLMSRLQEDSVPKGHKMTE----- 477
NP +I + + QED+HE+ M + +++ +P GHK +
Sbjct: 138 -------NPGHVIQPSQALAAGFHRGKQEDAHEFLMFTVDAMKKACLP-GHKQVDHHSKD 189
Query: 478 -SIIYDVFGGLLQQSVKCSNCGEISTTEQPIYDLSLHLKGRKTTDQDQNSVGQDNSIDNS 536
++I+ +FGG + +KC +C IS T P D++L ++ +
Sbjct: 190 TTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQ------------------ 231
Query: 537 VDQQQSSKRRFSIEKSIRDFFNPELIKRVDNKEGYTCEKCKKVTNALKSNKIIRAPETLV 596
S+++++ PE ++ + Y C C + A K+ + + + L+
Sbjct: 232 -----------SVQQALEQLVKPE---ELNGENAYHCGVCLQRAPASKTLTLHTSAKVLI 277
Query: 597 VHLKKFRFNGTSSSKMKQAVSYPMFLDLTEYCHESISSLPVRYQLISVVVHEGRSLSSGH 656
+ LK RF+ + +K+ + V YP LD+ Y + + P+ Y L +V+VH G S +GH
Sbjct: 278 LVLK--RFSDVTGNKIAKNVQYPECLDMQPYMSQQNTG-PLVYVLYAVLVHAGWSCHNGH 334
Query: 657 YIAHCKQPDGSWATYDDEYINKISEKQLLKEPNAYFLVY 695
Y ++ K +G W DD + S +L + AY L Y
Sbjct: 335 YFSYVKAQEGQWYKMDDAEVTASSITSVLTQ-QAYVLFY 372
>Hs22044551 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 530
Score = 115 bits (287), Expect = 3e-25
Identities = 83/339 (24%), Positives = 149/339 (43%), Gaps = 53/339 (15%)
Query: 363 GLLNHGVTCYTNAAVQAMVHIPAIQHYLFQLLRGNFKDTVKSNCVSMLLAETTMRMWSSD 422
GL N G TCY NA++Q + + P + +Y+ K + + A T +
Sbjct: 81 GLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALH--- 137
Query: 423 STKNTYINPDKLINALEDINCMMSAWNQEDSHEYFMSLMSRLQEDSVPKGHKMTE----- 477
NP +I + + QED+HE+ M + +++ +P GHK +
Sbjct: 138 -------NPGHVIQPSQALAAGFHRGKQEDAHEFLMFTVDAMKKACLP-GHKQVDHHSKD 189
Query: 478 -SIIYDVFGGLLQQSVKCSNCGEISTTEQPIYDLSLHLKGRKTTDQDQNSVGQDNSIDNS 536
++I+ +FGG + +KC +C IS T P D++L ++ +
Sbjct: 190 TTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQ------------------ 231
Query: 537 VDQQQSSKRRFSIEKSIRDFFNPELIKRVDNKEGYTCEKCKKVTNALKSNKIIRAPETLV 596
S+++++ PE ++ + Y C C + A K+ + + + L+
Sbjct: 232 -----------SVQQALEQLVKPE---ELNGENAYHCGVCLQRAPASKTLTLHTSAKVLI 277
Query: 597 VHLKKFRFNGTSSSKMKQAVSYPMFLDLTEYCHESISSLPVRYQLISVVVHEGRSLSSGH 656
+ LK RF+ + +K+ + V YP LD+ Y + + P+ Y L +V+VH G S +GH
Sbjct: 278 LVLK--RFSDVTGNKIAKNVQYPECLDMQPYMSQQNTG-PLVYVLYAVLVHAGWSCHNGH 334
Query: 657 YIAHCKQPDGSWATYDDEYINKISEKQLLKEPNAYFLVY 695
Y ++ K +G W DD + S +L + AY L Y
Sbjct: 335 YFSYVKAQEGQWYKMDDAEVTASSITSVLTQ-QAYVLFY 372
>Hs22044541 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 525
Score = 114 bits (285), Expect = 5e-25
Identities = 82/339 (24%), Positives = 151/339 (44%), Gaps = 58/339 (17%)
Query: 363 GLLNHGVTCYTNAAVQAMVHIPAIQHYLFQLLRGNFKDTVKSNCVSMLLAETTMRMWSSD 422
GL N G TCY NA++Q + + P + +Y+ ++ ++ C+ + R
Sbjct: 81 GLQNMGNTCYVNASLQCLTYTPPLANYMLS------REHSQNGCMLCTMQAHITRALH-- 132
Query: 423 STKNTYINPDKLINALEDINCMMSAWNQEDSHEYFMSLMSRLQEDSVPKGHKMTE----- 477
NP +I + + QED+HE+ M + +++ +P GHK +
Sbjct: 133 -------NPGHVIQPSQALAAGFHRGKQEDAHEFLMFTVDAMKKACLP-GHKQVDHHAKD 184
Query: 478 -SIIYDVFGGLLQQSVKCSNCGEISTTEQPIYDLSLHLKGRKTTDQDQNSVGQDNSIDNS 536
++I+ +FGG + +KC +C IS T P D++L ++ +
Sbjct: 185 TTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQ------------------ 226
Query: 537 VDQQQSSKRRFSIEKSIRDFFNPELIKRVDNKEGYTCEKCKKVTNALKSNKIIRAPETLV 596
S+++++ PE ++ + Y C C + A K+ + + + L+
Sbjct: 227 -----------SVQQALEQLVKPE---ELNGENAYHCGVCLQRAPASKTLTLHTSAKVLI 272
Query: 597 VHLKKFRFNGTSSSKMKQAVSYPMFLDLTEYCHESISSLPVRYQLISVVVHEGRSLSSGH 656
+ LK RF+ + +K+ + V YP LD+ Y + + P+ Y L +V+VH G S +GH
Sbjct: 273 LVLK--RFSDVTGNKIAKNVQYPECLDMQPYMSQQNTG-PLVYVLYAVLVHAGWSCHNGH 329
Query: 657 YIAHCKQPDGSWATYDDEYINKISEKQLLKEPNAYFLVY 695
Y ++ K +G W DD + S +L + AY L Y
Sbjct: 330 YFSYVKAQEGQWYKMDDAEVTASSITSVLTQ-QAYVLFY 367
>Hs22044539 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 1074
Score = 114 bits (285), Expect = 5e-25
Identities = 82/339 (24%), Positives = 151/339 (44%), Gaps = 58/339 (17%)
Query: 363 GLLNHGVTCYTNAAVQAMVHIPAIQHYLFQLLRGNFKDTVKSNCVSMLLAETTMRMWSSD 422
GL N G TCY NA++Q + + P + +Y+ ++ ++ C+ + R
Sbjct: 630 GLQNMGNTCYVNASLQCLTYTPPLANYMLS------REHSQNGCMLCTMQAHITRALH-- 681
Query: 423 STKNTYINPDKLINALEDINCMMSAWNQEDSHEYFMSLMSRLQEDSVPKGHKMTE----- 477
NP +I + + QED+HE+ M + +++ +P GHK +
Sbjct: 682 -------NPGHVIQPSQALAAGFHRGKQEDAHEFLMFTVDAMKKACLP-GHKQVDHHSKD 733
Query: 478 -SIIYDVFGGLLQQSVKCSNCGEISTTEQPIYDLSLHLKGRKTTDQDQNSVGQDNSIDNS 536
++I+ +FGG + +KC +C IS T P D++L ++ +
Sbjct: 734 TTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQ------------------ 775
Query: 537 VDQQQSSKRRFSIEKSIRDFFNPELIKRVDNKEGYTCEKCKKVTNALKSNKIIRAPETLV 596
S+++++ PE ++ + Y C C + A K+ + + + L+
Sbjct: 776 -----------SVQQALEQLVKPE---ELNGENAYHCGVCLQRAPASKTLTLHTSAKVLI 821
Query: 597 VHLKKFRFNGTSSSKMKQAVSYPMFLDLTEYCHESISSLPVRYQLISVVVHEGRSLSSGH 656
+ LK RF+ + +K+ + V YP LD+ Y + + P+ Y L +V+VH G S +GH
Sbjct: 822 LVLK--RFSDVTGNKIAKNVQYPECLDMQPYMSQQNTG-PLVYVLYAVLVHAGWSCHNGH 878
Query: 657 YIAHCKQPDGSWATYDDEYINKISEKQLLKEPNAYFLVY 695
Y ++ K +G W DD + S +L + AY L Y
Sbjct: 879 YFSYVKAQEGQWYKMDDAEVTASSITSVLTQ-QAYVLFY 916
Score = 108 bits (270), Expect = 3e-23
Identities = 82/339 (24%), Positives = 148/339 (43%), Gaps = 55/339 (16%)
Query: 363 GLLNHGVTCYTNAAVQAMVHIPAIQHYLFQLLRGNFKDTVKSNCVSMLLAETTMRMWSSD 422
GL N G TCY NA++Q + + P + +Y+ K + + A T +
Sbjct: 81 GLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCYRHKGCMLCTMQAHITRALH--- 137
Query: 423 STKNTYINPDKLINALEDINCMMSAWNQEDSHEYFMSLMSRLQEDSVPKGHKMTE----- 477
NP +I + + QED+HE+ M + +++ +P GHK +
Sbjct: 138 -------NPGHVIQPSQALAAGFHRGKQEDAHEFLMFTVDAMKKACLP-GHKQVDHHSKD 189
Query: 478 -SIIYDVFGGLLQQSVKCSNCGEISTTEQPIYDLSLHLKGRKTTDQDQNSVGQDNSIDNS 536
++I+ +FGG + +KC +C IS T P D++L ++ +
Sbjct: 190 TTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQ------------------ 231
Query: 537 VDQQQSSKRRFSIEKSIRDFFNPELIKRVDNKEGYTCEKCKKVTNALKSNKIIRAPETLV 596
S+++++ PE ++ + Y C C + A K+ + + + L+
Sbjct: 232 -----------SVQQALEQLVKPE---ELNGENAYHCGVCLQRAPASKTLTLHTSAKVLI 277
Query: 597 VHLKKFRFNGTSSSKMKQAVSYPMFLDLTEYCHESISSLPVRYQLISVVVHEGRSLSSGH 656
+ LK RF+ + +K+ + V YP LD+ Y + + P+ Y L +V+VH G +GH
Sbjct: 278 LVLK--RFSDVTGNKIAKNVQYPECLDMQPYMSQQNTG-PLVYVLYAVLVHAG--CYNGH 332
Query: 657 YIAHCKQPDGSWATYDDEYINKISEKQLLKEPNAYFLVY 695
Y ++ K +G W DD + S +L + AY L Y
Sbjct: 333 YFSYVKAQEGQWYKMDDAEVTASSITSVLTQ-QAYVLFY 370
>Hs22065367 [O] KOG1867 Ubiquitin-specific protease
Length = 525
Score = 114 bits (284), Expect = 7e-25
Identities = 94/355 (26%), Positives = 154/355 (42%), Gaps = 34/355 (9%)
Query: 362 RGLLNHGVTCYTNAAVQAMVHIPAIQHYLFQLLRGNFKDTVKSNCVSMLLAETTMRMWSS 421
RGL+N G TC+ N VQA+ H P ++ + F R + S+C+ ++ +S
Sbjct: 176 RGLINLGNTCFMNCIVQALTHTPLLRDF-FLSDRHRCEMQSPSSCLVCEMSSLFQEFYSG 234
Query: 422 DSTKNTYINPDKLINALEDINCMMSAWNQEDSHEYFMSLMSRLQ-----EDSVPKGHKMT 476
+ + P KL++ + ++ + Q+D+HE+ ++ + L +D+ K +
Sbjct: 235 HRSPHI---PYKLLHLVWTHARHLAGYEQQDAHEFLIAALDVLHRHCKGDDNGKKANNPN 291
Query: 477 ES--IIYDVFGGLLQQSVKCSNCGEISTTEQPIYDLSLHLKGRKTTDQDQNSVGQDNSID 534
II +F G LQ V C C +STT P +D+SL L G T S G + ++
Sbjct: 292 HCNCIIDQIFTGGLQSDVTCQVCHGVSTTIDPFWDISLDLPGSSTPFWPL-SPGSEGNVV 350
Query: 535 NSVDQQQSSKRRFSIEKSIRDFFNPELIKRVDNKEGYTCEKCKKVTNALKSNKIIRAPET 594
N + ++ +R F PE + + C C + K + + P
Sbjct: 351 NGESHVSGTT---TLTDCLRRFTRPE---HLGSSAKIKCSGCHSYQESTKQLTMKKLPIV 404
Query: 595 LVVHLKKFRFNGTSSSKMKQAVSYPMFLDLTEYCHESISSL--------------PVRYQ 640
HLK+F + K+ VS+P+ LD+T + S S +Y
Sbjct: 405 ACFHLKRFEHSAKLRRKITTYVSFPLELDMTPFMASSKESRMNGQYQQPTDSLNNDNKYS 464
Query: 641 LISVVVHEGRSLSSGHYIAHCKQPDGSWATYDDEYINKISEKQLLKEPNAYFLVY 695
L +VV H+G +L SGHY + +Q W DD I K S K +L + Y L Y
Sbjct: 465 LFAVVNHQG-TLESGHYTSFIRQHKDQWFKCDDAIITKASIKDVL-DSEGYLLFY 517
>HsM18874088 [O] KOG1870 Ubiquitin C-terminal hydrolase
Length = 942
Score = 113 bits (283), Expect = 9e-25
Identities = 81/268 (30%), Positives = 132/268 (49%), Gaps = 32/268 (11%)
Query: 471 KGHKMTESIIYDVFGGLLQQSVKCSNCGEISTTEQPIYDLSLHLKGRK-----------T 519
K HK S+I D+F G + SV+C C +S T + DLSL + G++ T
Sbjct: 466 KQHKKYRSVISDIFDGTIISSVQCLTCDRVSVTLETFQDLSLPIPGKEDLAKLHSSSHPT 525
Query: 520 TDQDQNSVGQDNSIDNSVDQQQSSKRRF--------------SIEKSIRDFFNPELIKRV 565
+ S G+ + + +RF +++ + FF + +K
Sbjct: 526 SIVKAGSCGEAYAPQGWIAFFMEYVKRFVVSCVPSWFWGPVVTLQDCLAAFFARDELKG- 584
Query: 566 DNKEGYTCEKCKKVTNALKSNKIIRAPETLVVHLKKFRFNGTSSSKMKQAVSYPM-FLDL 624
DN Y+CEKCKK+ N +K K+ PE L +HLK+FR S+K+ VS+P+ LDL
Sbjct: 585 DNM--YSCEKCKKLRNGVKFCKVQNFPEILCIHLKRFRHELMFSTKISTHVSFPLEGLDL 642
Query: 625 TEYCHESISSLPVRYQLISVVVHEGRSLSSGHYIAHCKQP-DGSWATYDDEYINKISEKQ 683
+ + + V Y L+SV+ H G + SSGHYIA+C+ + W +DD+ + ++SE
Sbjct: 643 QPFLAKDSPAQIVTYDLLSVICHHG-TASSGHYIAYCRNNLNNLWYEFDDQSVTEVSE-S 700
Query: 684 LLKEPNAYFLVYTRLTPKSVPLSSQSSN 711
++ AY L Y + + ++ + SN
Sbjct: 701 TVQNAEAYVLFYRKSSEEAQKERRRISN 728
>Hs21489975 [O] KOG1870 Ubiquitin C-terminal hydrolase
Length = 911
Score = 113 bits (283), Expect = 9e-25
Identities = 81/268 (30%), Positives = 132/268 (49%), Gaps = 32/268 (11%)
Query: 471 KGHKMTESIIYDVFGGLLQQSVKCSNCGEISTTEQPIYDLSLHLKGRK-----------T 519
K HK S+I D+F G + SV+C C +S T + DLSL + G++ T
Sbjct: 435 KQHKKYRSVISDIFDGTIISSVQCLTCDRVSVTLETFQDLSLPIPGKEDLAKLHSSSHPT 494
Query: 520 TDQDQNSVGQDNSIDNSVDQQQSSKRRF--------------SIEKSIRDFFNPELIKRV 565
+ S G+ + + +RF +++ + FF + +K
Sbjct: 495 SIVKAGSCGEAYAPQGWIAFFMEYVKRFVVSCVPSWFWGPVVTLQDCLAAFFARDELKG- 553
Query: 566 DNKEGYTCEKCKKVTNALKSNKIIRAPETLVVHLKKFRFNGTSSSKMKQAVSYPM-FLDL 624
DN Y+CEKCKK+ N +K K+ PE L +HLK+FR S+K+ VS+P+ LDL
Sbjct: 554 DNM--YSCEKCKKLRNGVKFCKVQNFPEILCIHLKRFRHELMFSTKISTHVSFPLEGLDL 611
Query: 625 TEYCHESISSLPVRYQLISVVVHEGRSLSSGHYIAHCKQP-DGSWATYDDEYINKISEKQ 683
+ + + V Y L+SV+ H G + SSGHYIA+C+ + W +DD+ + ++SE
Sbjct: 612 QPFLAKDSPAQIVTYDLLSVICHHG-TASSGHYIAYCRNNLNNLWYEFDDQSVTEVSE-S 669
Query: 684 LLKEPNAYFLVYTRLTPKSVPLSSQSSN 711
++ AY L Y + + ++ + SN
Sbjct: 670 TVQNAEAYVLFYRKSSEEAQKERRRISN 697
>7295645 [O] KOG1868 Ubiquitin C-terminal hydrolase
Length = 857
Score = 112 bits (281), Expect = 2e-24
Identities = 100/364 (27%), Positives = 153/364 (41%), Gaps = 69/364 (18%)
Query: 363 GLLNHGVTCYTNAAVQAMVHIPAIQHYLFQLLRGNFKDTVKSNCVSMLLAETTMRMWSSD 422
GL N G TC+ N+ +Q + H + +L + G+ + K + A+ MW
Sbjct: 533 GLRNIGNTCFMNSVIQCLSHTQELTRFL-RSHHGSRSLSTKDQQILHEFAKLIQEMW--- 588
Query: 423 STKNTY-INPDKLINALEDINCMMSAWNQEDSHEYFMSLMSRLQE--DSVPKGHKMT--- 476
T N + + P +L A + M S +NQ+D+ E+ + L +S KG +
Sbjct: 589 -TANVHTVTPMELKRAFSTKHRMYSDYNQQDAQEFLRFFLDSLHSALNSGVKGETLNIDD 647
Query: 477 -------------------ESIIYDVFGGLLQQSVKCSNCGEISTTEQPIYDLSLHLKGR 517
S++ D+F G L+ ++KC+ CG S T P +DLS+ L
Sbjct: 648 NLSDNKKADLTWEWYTRHENSLVRDLFVGQLKSTLKCTTCGNTSVTFDPFWDLSVPLP-- 705
Query: 518 KTTDQDQNSVGQDNSIDNSVDQQQSSKRRFSIEKSIRDFFNPELIKRVDNKEGYTCEKCK 577
S R +E + F E++ D E TC KCK
Sbjct: 706 -------------------------SSSRCKLEACLDLFIREEVL---DGDEMPTCAKCK 737
Query: 578 KVTNALKSNKIIRAPETLVVHLKKFRFNGTSSSKMKQAVSYPMF---LDLTEYCHESISS 634
KS I R P+ LV+HLK RF+ T SK+ V +P L++ Y S S+
Sbjct: 738 TRRKCTKSFTIQRFPKYLVIHLK--RFSETRWSKLSNIVEFPTSDSELNMGSYGANSNSN 795
Query: 635 LPVRYQLISVVVHEGRSLSSGHYIAHCKQP-DGSWATYDDEYINKISEKQLLKEPNAYFL 693
V Y L ++ H G S + GHY+A CK P W ++D ++ + L +AY L
Sbjct: 796 --VHYSLYAISNHMG-STAGGHYVALCKHPVSRKWHEFNDNIVSDALSENHLVSSSAYIL 852
Query: 694 VYTR 697
Y R
Sbjct: 853 FYER 856
>Hs4827054 [O] KOG1868 Ubiquitin C-terminal hydrolase
Length = 1118
Score = 111 bits (278), Expect = 4e-24
Identities = 102/371 (27%), Positives = 164/371 (43%), Gaps = 68/371 (18%)
Query: 363 GLLNHGVTCYTNAAVQAMVHIPAIQHYLFQLLRGNFKDTV-KSNCVSM---LLAETTMRM 418
GL N G TCY N+ +Q + + P + Y R ++D + +SN + + E + M
Sbjct: 778 GLRNLGNTCYMNSILQCLCNAPHLADYFN---RNCYQDDINRSNLLGHKGEVAEEFGIIM 834
Query: 419 WSSDSTKNTYINPDKLINALEDINCMMSAWNQEDSHEYFMSLMSRLQED----------- 467
+ + + YI+P + IN + ++Q+DS E + LM L ED
Sbjct: 835 KALWTGQYRYISPKDFKITIGKINDQFAGYSQQDSQELLLFLMDGLHEDLNKADNRKRYK 894
Query: 468 ---------------SVPKGHKMTESIIYDVFGGLLQQSVKCSNCGEISTTEQPIYDLSL 512
+ K ++ ESII +F G + +V+C C + S T + LSL
Sbjct: 895 EENNDHLDDFKAAEHAWQKHKQLNESIIVALFQGQFKSTVQCLTCHKKSRTFEAFMYLSL 954
Query: 513 HLKGRKTTDQDQNSVGQDNSIDNSVDQQQSSKRRFSIEKSIRDFFNPELIKRVDNKEGYT 572
L +S + +++ +R F E K DN Y
Sbjct: 955 PL---------------------------ASTSKCTLQDCLRLFSKEE--KLTDNNRFY- 984
Query: 573 CEKCKKVTNALKSNKIIRAPETLVVHLKKFRFNGTSSSKMKQAVSYPM-FLDLTEYCHES 631
C C+ ++LK +I + P L+VHLK+F ++G K++ +V +P+ LDL++Y
Sbjct: 985 CSHCRARRDSLKKIEIWKLPPVLLVHLKRFSYDGRWKQKLQTSVDFPLENLDLSQYVIGP 1044
Query: 632 ISSLPVRYQLISVVVHEGRSLSSGHYIAHCKQPDGS-WATYDDEYINKISEKQLLKEPNA 690
++L +Y L SV H G L GHY A+CK W +DD ++ IS +K A
Sbjct: 1045 KNNLK-KYNLFSVSNHYG-GLDGGHYTAYCKNAARQRWFKFDDHEVSDISVSS-VKSSAA 1101
Query: 691 YFLVYTRLTPK 701
Y L YT L P+
Sbjct: 1102 YILFYTSLGPR 1112
>Hs22044534 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 530
Score = 111 bits (278), Expect = 4e-24
Identities = 80/338 (23%), Positives = 146/338 (42%), Gaps = 51/338 (15%)
Query: 363 GLLNHGVTCYTNAAVQAMVHIPAIQHYLFQLLRGNFKDTVKSNCVSMLLAETTMRMWSSD 422
GL N G TCY NA++Q + + + +Y+ K + + A T +
Sbjct: 81 GLQNMGNTCYVNASLQCLTYTTPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALH--- 137
Query: 423 STKNTYINPDKLINALEDINCMMSAWNQEDSHEYFMSLMSRLQEDSVPKG-----HKMTE 477
NP +I + + QED+HE+ M + +++ +P+ H
Sbjct: 138 -------NPGHVIQPSQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPRHKQVDHHSKDT 190
Query: 478 SIIYDVFGGLLQQSVKCSNCGEISTTEQPIYDLSLHLKGRKTTDQDQNSVGQDNSIDNSV 537
++I+ +FGG + +KC +C IS T P D++L ++ +
Sbjct: 191 TLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQ------------------- 231
Query: 538 DQQQSSKRRFSIEKSIRDFFNPELIKRVDNKEGYTCEKCKKVTNALKSNKIIRAPETLVV 597
S+++++ PE ++ + Y C C + A K+ + + + L++
Sbjct: 232 ----------SVQQALEQLVKPE---ELNGENAYHCGVCLQRAPASKTLTLHTSAKVLIL 278
Query: 598 HLKKFRFNGTSSSKMKQAVSYPMFLDLTEYCHESISSLPVRYQLISVVVHEGRSLSSGHY 657
LK RF+ + +K+ + V YP LD+ Y + + P+ Y L +V+VH G S +GHY
Sbjct: 279 VLK--RFSDVTGNKIAKNVQYPECLDMQPYMSQQNTG-PLVYVLYAVLVHAGWSCHNGHY 335
Query: 658 IAHCKQPDGSWATYDDEYINKISEKQLLKEPNAYFLVY 695
++ K +G W DD + S +L + AY L Y
Sbjct: 336 FSYVKAQEGQWYKMDDAEVTAASITSVLSQ-QAYVLFY 372
>SPAC13A11.04c [O] KOG1867 Ubiquitin-specific protease
Length = 449
Score = 111 bits (277), Expect = 5e-24
Identities = 84/335 (25%), Positives = 153/335 (45%), Gaps = 48/335 (14%)
Query: 362 RGLLNHGVTCYTNAAVQAMVHIPAIQHYLFQLLRGNFKDTVKSNCVSMLLAETTMRMWSS 421
RG+ N G TC+ + +Q+++H P +++ F + D + C++ + + +++S
Sbjct: 145 RGIQNLGATCFMSVILQSILHNPLVRNLFFSGFHTS-TDCKRPTCMTCAIDDMFSSIYNS 203
Query: 422 DSTKNTYINPDKLINALEDINCMMSAWNQEDSHEYFMSLMSRLQEDSVPKGHKMTESIIY 481
+ K+T+ P ++N + ++ + ++Q+D HE+F+ L+ ++ +S I+
Sbjct: 204 KN-KSTFYGPTAVLNLMWKLSKSLCGYSQQDGHEFFVYLLDQMHTESGGGTSMPCTCPIH 262
Query: 482 DVFGGLLQQSVKCSNCGEISTTEQPIYDLSLHLKGRKTTDQDQNSVGQDNSIDNSVDQQQ 541
+F G L+ V C +C + P+ D+SL D + Q
Sbjct: 263 RIFSGSLKNVVTCLDCKKERVAVDPLMDISL---------------------DINEPTLQ 301
Query: 542 SSKRRFSIEKSIRDFFNPELIKRVDNKEGYTCEKCKKVTNALKSNKIIRAPETLVVHLKK 601
RF ++ ++ Y+C C NA+K + P T+ + LK+
Sbjct: 302 GCLERFVSKEKVQ----------------YSCHSCGS-KNAIKQLVFDKLPPTICMQLKR 344
Query: 602 FRFNG-TSSSKMKQAVSYPMFLDLTEYCHESISSLPVRYQLISVVVHEGRSLSSGHYIAH 660
F N S+K+ + VSYP FL + + + V YQL SVV H+G +L +GHYIA+
Sbjct: 345 FEQNNFAMSTKIDKQVSYPAFLRM----RYNFNQDDVDYQLYSVVCHKG-TLDTGHYIAY 399
Query: 661 CKQPDGSWATYDDEYINKISEKQLLKEPNAYFLVY 695
W DD I ++ E ++L AY L Y
Sbjct: 400 TYY-QNQWFLLDDTTIVEVKESEVLNS-QAYLLFY 432
>Hs22044537 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 530
Score = 110 bits (276), Expect = 6e-24
Identities = 87/339 (25%), Positives = 155/339 (45%), Gaps = 53/339 (15%)
Query: 363 GLLNHGVTCYTNAAVQAMVHIPAIQHYLFQLLRGNFKDTVKSNCVSMLLAETTMRMWSSD 422
GL N G TCY NA++Q + + P + +Y+ L T + ML TM+ +
Sbjct: 81 GLQNMGNTCYVNASLQCLTYKPPLANYM---LFREHSQTCHRHKGCMLC---TMQ---AH 131
Query: 423 STKNTYINPDKLINALEDINCMMSAWNQEDSHEYFMSLMSRLQEDSVPKGHKMTE----- 477
T+ +I P +I + + QED+HE+ M + +++ +P GHK +
Sbjct: 132 ITRALHI-PGHVIQPSQALAAGFHRGKQEDAHEFLMFTVDAMRKACLP-GHKQVDRHSKD 189
Query: 478 -SIIYDVFGGLLQQSVKCSNCGEISTTEQPIYDLSLHLKGRKTTDQDQNSVGQDNSIDNS 536
++I+ +FGG + +KC +C IS T P D++L ++ +
Sbjct: 190 TTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQ------------------ 231
Query: 537 VDQQQSSKRRFSIEKSIRDFFNPELIKRVDNKEGYTCEKCKKVTNALKSNKIIRAPETLV 596
S+++++ PE ++ + Y C C + A K+ + + + L+
Sbjct: 232 -----------SVQQALEQLVKPE---ELNGENAYHCGVCLQRAPASKTLTLHTSAKVLI 277
Query: 597 VHLKKFRFNGTSSSKMKQAVSYPMFLDLTEYCHESISSLPVRYQLISVVVHEGRSLSSGH 656
+ LK RF+ + +K+ + V YP LD+ Y + + P+ Y L +V+VH G S +GH
Sbjct: 278 LVLK--RFSDVTGNKIAKNVQYPECLDMQPYMSQQNTG-PLVYVLYAVLVHAGWSCHNGH 334
Query: 657 YIAHCKQPDGSWATYDDEYINKISEKQLLKEPNAYFLVY 695
Y ++ K +G W DD + S +L + AY L Y
Sbjct: 335 YFSYVKAQEGQWYKMDDAEVTASSITSVLTQ-QAYVLFY 372
>Hs18557591 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 530
Score = 109 bits (273), Expect = 1e-23
Identities = 87/339 (25%), Positives = 154/339 (44%), Gaps = 53/339 (15%)
Query: 363 GLLNHGVTCYTNAAVQAMVHIPAIQHYLFQLLRGNFKDTVKSNCVSMLLAETTMRMWSSD 422
GL N G TCY NA++Q + + P + +Y+ L T + ML TM+ +
Sbjct: 81 GLQNMGNTCYVNASLQCLTYKPPLANYM---LFREHSQTCHRHKGCMLC---TMQ---AH 131
Query: 423 STKNTYINPDKLINALEDINCMMSAWNQEDSHEYFMSLMSRLQEDSVPKGHKMTE----- 477
T+ +I P +I + + QED+HE+ M + +++ +P GHK +
Sbjct: 132 ITRALHI-PGHVIQPSQALAAGFHRGKQEDAHEFLMFTVDAMRKACLP-GHKQVDRHSKD 189
Query: 478 -SIIYDVFGGLLQQSVKCSNCGEISTTEQPIYDLSLHLKGRKTTDQDQNSVGQDNSIDNS 536
++I+ +FGG + +KC +C IS T P D++L ++ +
Sbjct: 190 TTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQ------------------ 231
Query: 537 VDQQQSSKRRFSIEKSIRDFFNPELIKRVDNKEGYTCEKCKKVTNALKSNKIIRAPETLV 596
S+++++ PE ++ + Y C C + A K+ + + + L+
Sbjct: 232 -----------SVQQALEQLVKPE---ELNGENAYHCGVCLQRAPASKTLTLHNSAKVLI 277
Query: 597 VHLKKFRFNGTSSSKMKQAVSYPMFLDLTEYCHESISSLPVRYQLISVVVHEGRSLSSGH 656
+ LK RF + +K+ + V YP LD+ Y + + P+ Y L +V+VH G S +GH
Sbjct: 278 LVLK--RFPDVTGNKIAKNVQYPECLDMQPYMSQQNTG-PLVYVLYAVLVHAGWSCHNGH 334
Query: 657 YIAHCKQPDGSWATYDDEYINKISEKQLLKEPNAYFLVY 695
Y ++ K +G W DD + S +L + AY L Y
Sbjct: 335 YSSYVKAQEGQWYKMDDAEVTASSITSVLSQ-QAYVLFY 372
>At4g24560 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 1008
Score = 109 bits (272), Expect = 2e-23
Identities = 93/397 (23%), Positives = 163/397 (40%), Gaps = 57/397 (14%)
Query: 334 NESINDHGSNK--PQRIVKNWGSKLTQLKPRGLLNHGVTCYTNAAVQAMVHIPAIQHYLF 391
NE HG P + + + +P GL+N G +C+ N Q ++ P + Y
Sbjct: 512 NEMAGRHGHKGLFPYEVFAKLYTYKIEFQPCGLINVGNSCFANVVFQCLMFTPPLTTYFL 571
Query: 392 QLLRGNFKDTVKSNCVSMLLAETTMRMWSSDSTKNTYINPDKLINALEDINCMMSAWNQE 451
Q T K C + + ++ S ++P+ L++ L++I + +E
Sbjct: 572 QQFHSR-ACTKKEQCFTCGFEKLVVKAKEEKSP----LSPNGLLSQLQNIGIFLGNGKEE 626
Query: 452 DSHEYFMSLMSRLQ-------EDSVPKGHKMTESIIYDV-FGGLLQQSVKCSNCGEISTT 503
D+HE+ ++ +Q E + K K+ ++ + + FGG L+ +KC C S
Sbjct: 627 DAHEFLRFVVDTMQSVCIKASEYDMTKSSKLEDTTLIGLTFGGYLRSKIKCMKCQVKSEL 686
Query: 504 EQPIYDLSLHLKGRKTTDQDQNSVGQDNSIDNSVDQQQSSKRRFSIEKSIRDFFNPELIK 563
+ + DL++ + G +T ++ ++R F E++
Sbjct: 687 REKMMDLTVEIDGDIST----------------------------LDDALRRFTRTEIL- 717
Query: 564 RVDNKEGYTCEKCKKVTNALKSNKIIRAPETLVVHLKKFRFNGTSSSKMKQAVSYPMFLD 623
D + Y C CK A K KI P L + LK RF K+ + + +P LD
Sbjct: 718 --DGENKYRCGSCKSYERAKKKLKITEPPNVLTIALK--RFQAGKFGKLNKLIRFPETLD 773
Query: 624 LTEYCHESISSLPVRYQLISVVVHEG--RSLSSGHYIAHCKQPDGSWATYDDEYINKISE 681
L Y S Y+L V+VH + SGHY+ + + W DD +
Sbjct: 774 LAPYVSGG-SEKSHDYKLYGVIVHLDVMNAAFSGHYVCYIRN-QNKWYKADDSTVVTSDV 831
Query: 682 KQLLKEPNAYFLVYTRLTPK----SVPLSSQSSNKST 714
+++L + AY L Y R TP +V +++SNK +
Sbjct: 832 ERILTK-GAYMLFYARCTPTPPRLAVCTKTEASNKKS 867
>7293885 [O] KOG1867 Ubiquitin-specific protease
Length = 735
Score = 109 bits (272), Expect = 2e-23
Identities = 90/361 (24%), Positives = 149/361 (40%), Gaps = 57/361 (15%)
Query: 362 RGLLNHGVTCYTNAAVQAMVHIPAIQHYLFQLLRGNFKDTVKSNCVSMLLAETTMRMWSS 421
RGLLN G TC+ N VQA+VH P + Y + D + L+ E +
Sbjct: 397 RGLLNLGATCFMNCIVQALVHTPLLSDYFM----SDRHDCGSKSSHKCLVCEVSRLFQEF 452
Query: 422 DSTKNTYINPDKLINALEDINCMMSAWNQEDSHEYFMSLMSRLQEDSV-PKGHKMTES-- 478
S + ++ +L++ + + ++ + Q+D+HE+F++ + L V K ++S
Sbjct: 453 YSGSRSPLSLHRLLHLIWNHAKHLAGYEQQDAHEFFIATLDVLHRHCVKAKAEHESKSNS 512
Query: 479 -----------------------IIYDVFGGLLQQSVKCSNCGEISTTEQPIYDLSLHLK 515
II +F G+LQ V C C +STT P +D+SL L
Sbjct: 513 SGSGSGTNSSNSSSSHCYGQCNCIIDQIFTGMLQSDVVCQACNGVSTTYDPFWDISLDL- 571
Query: 516 GRKTTDQDQNSVGQDNSIDNSVDQQQSSKRRFSIEKSIRDFFNPELIKRVDNKEGYTCEK 575
G TT V ID +E+ R + + + C
Sbjct: 572 GETTT---HGGVTPKTLID-------------CLERYTR-------AEHLGSAAKIKCST 608
Query: 576 CKKVTNALKSNKIIRAPETLVVHLKKFRFNGTSSSKMKQAVSYPMFLDLTEYCHESISSL 635
CK + K + P + HLK+F + K+ + +P+ D+T + E ++
Sbjct: 609 CKSYQESTKQFSLRTLPSVVSFHLKRFEHSALIDRKISSFIQFPVEFDMTPFMSEKKNAY 668
Query: 636 -PVRYQLISVVVHEGRSLSSGHYIAHCKQPDGSWATYDDEYINKISEKQLLKEPNAYFLV 694
R+ L +VV H G ++ +GHY A+ + +W DD I S KQ+L + Y L
Sbjct: 669 GDFRFSLYAVVNHVG-TIDTGHYTAYVRHQKDTWVKCDDHVITMASLKQVL-DSEGYLLF 726
Query: 695 Y 695
Y
Sbjct: 727 Y 727
>HsM19923759 [O] KOG1868 Ubiquitin C-terminal hydrolase
Length = 605
Score = 108 bits (271), Expect = 2e-23
Identities = 95/370 (25%), Positives = 163/370 (43%), Gaps = 64/370 (17%)
Query: 363 GLLNHGVTCYTNAAVQAMVHIPAIQHYLFQLL--RGNFKDTVKSNCVSMLLAETTMRMWS 420
GL N G TC+ N+ +Q + + ++ Y Q L R + + A+ +W+
Sbjct: 268 GLRNLGNTCFMNSILQCLSNTRELRDYCLQRLYMRDLHHGSNAHTALVEEFAKLIQTIWT 327
Query: 421 SDSTKNTYINPDKLINALEDINCMMSAWNQEDSHEYFMSLMSRLQE-------------- 466
S + N ++P + ++ +NQ+D+ E+ L+ L
Sbjct: 328 S--SPNDVVSPSEFKTQIQRYAPRFVGYNQQDAQEFLRFLLDGLHNEVNRVTLRPKSNPE 385
Query: 467 --DSVP---KGHKM-------TESIIYDVFGGLLQQSVKCSNCGEISTTEQPIYDLSLHL 514
D +P KG +M +S I D+F G L+ S+ C++CG ST P +DLSL +
Sbjct: 386 NLDHLPDDEKGRQMWRKYLEREDSRIGDLFVGQLKSSLTCTDCGYCSTVFDPFWDLSLPI 445
Query: 515 KGRKTTDQDQNSVGQDNSIDNSVDQQQSSKRRFSIEKSIRDFFNPELIKRVDNKEGYTCE 574
R + ++ +R F +++ D E TC
Sbjct: 446 AKRGYPE-------------------------VTLMDCMRLFTKEDVL---DGDEKPTCC 477
Query: 575 KCKKVTNALKSNKIIRAPETLVVHLKKFRFNGTSSSKMKQAVSYPM-FLDLTEYCHESIS 633
+C+ +K I R P+ LV+HLK+F + +SK+ V++P+ LDL E+ E+ +
Sbjct: 478 RCRGRKRCIKKFSIQRFPKILVLHLKRFSESRIRTSKLTTFVNFPLRDLDLREFASENTN 537
Query: 634 SLPVRYQLISVVVHEGRSLSSGHYIAHCKQP-DGSWATYDDEYINKISEKQLLKEPNAYF 692
Y L +V H G ++ GHY A+C+ P G W T++D + +S Q ++ +AY
Sbjct: 538 H--AVYNLYAVSNHSGTTM-GGHYTAYCRSPGTGEWHTFNDSSVTPMSSSQ-VRTSDAYL 593
Query: 693 LVYTRLTPKS 702
L Y +P S
Sbjct: 594 LFYELASPPS 603
>7300711 [O] KOG1868 Ubiquitin C-terminal hydrolase
Length = 888
Score = 107 bits (267), Expect = 7e-23
Identities = 102/385 (26%), Positives = 159/385 (40%), Gaps = 69/385 (17%)
Query: 348 IVKNWGSKLTQLKPRGLLNHGVTCYTNAAVQAMVHIPAIQHYLFQLLRGNF--KDTVKSN 405
I +N G LT GL N G TCY N+ +Q + + P + Y N+ + +
Sbjct: 546 IGQNVGRGLT-----GLKNLGNTCYMNSILQCLSNTPQLTEYCISDKYKNYISRSNKTNG 600
Query: 406 CVSMLLAETTMRMWSSDSTKNTYINPDKLINALEDINCMMSAWNQEDSHEYFMSLMSRLQ 465
V +A +W+ + + L + + +Q+DSHE+ LM L
Sbjct: 601 QVIEEVAALIKELWNG---QYKCVASRDLRYVVGQYQKIFRGVDQQDSHEFLTILMDWLH 657
Query: 466 ED----SVPKGHKMT--------------ESIIYDVFGGLLQQSVKCSNCGEISTTEQPI 507
D VP+ +M ES+I +F G ++ +VKC C + S T +
Sbjct: 658 SDLQTLHVPRQREMISASEKAWLEFTKAKESMILHLFYGQMKSTVKCVACHKESATYESF 717
Query: 508 YDLSLHLKGRKTTDQDQNSVGQDNSIDNSVDQQQSSKRRFSIEKSIRDFFNPELIKRVDN 567
+LSL L Q + + + +F+ E I
Sbjct: 718 SNLSLELPPNSNVCQ--------------------------LNQCMDMYFSGERI----- 746
Query: 568 KEGYTCEKCKKVTNALKSNKIIRAPETLVVHLKKFRFNGTSSSKMKQAVSYPMF----LD 623
G+ C CK +A+K I + P LVVHLK+F + ++S + +Y F LD
Sbjct: 747 -HGWNCPSCKTKRDAIKKLDISKLPPVLVVHLKRFYADPSNSGSYMKKQNYLRFPLENLD 805
Query: 624 LTEYC--HESISSLPVRYQLISVVVHEGRSLSSGHYIAHCKQPD-GSWATYDDEYINKIS 680
+ Y ES + P YQL +V H G ++ GHY A CK + G W +DD+ ++ +
Sbjct: 806 MNPYIARAESRAVTPKTYQLYAVSNHYG-TMEGGHYTAFCKSANYGKWFKFDDQVVSALD 864
Query: 681 EKQLLKEPNAYFLVYTRLTPKSVPL 705
++ AY L YT L P VPL
Sbjct: 865 SSNVVSSA-AYILFYTWLPPMQVPL 888
>Hs22044528 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 446
Score = 106 bits (265), Expect = 1e-22
Identities = 77/333 (23%), Positives = 143/333 (42%), Gaps = 51/333 (15%)
Query: 368 GVTCYTNAAVQAMVHIPAIQHYLFQLLRGNFKDTVKSNCVSMLLAETTMRMWSSDSTKNT 427
G TCY NA++Q + + P + +Y+ K + + A T +
Sbjct: 2 GNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALH-------- 53
Query: 428 YINPDKLINALEDINCMMSAWNQEDSHEYFMSLMSRLQEDSVPKG-----HKMTESIIYD 482
NP +I + + QED+HE+ M + +++ +P+ H ++I+
Sbjct: 54 --NPGHVIQPSQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPRHKQVDHHSKDTTLIHQ 111
Query: 483 VFGGLLQQSVKCSNCGEISTTEQPIYDLSLHLKGRKTTDQDQNSVGQDNSIDNSVDQQQS 542
+FGG + +KC +C IS T P D++L ++ +
Sbjct: 112 IFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQ------------------------ 147
Query: 543 SKRRFSIEKSIRDFFNPELIKRVDNKEGYTCEKCKKVTNALKSNKIIRAPETLVVHLKKF 602
S+++++ PE ++ + Y C C + A K+ + + + L++ LK
Sbjct: 148 -----SVQQALEQLVKPE---ELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLK-- 197
Query: 603 RFNGTSSSKMKQAVSYPMFLDLTEYCHESISSLPVRYQLISVVVHEGRSLSSGHYIAHCK 662
RF+ + +K+ + V YP LD+ Y + + P+ Y L +V+VH S +GHY ++ K
Sbjct: 198 RFSDVTGNKIAKNVQYPECLDMQPYMSQQNTG-PLVYVLYAVLVHAEWSCHNGHYFSYVK 256
Query: 663 QPDGSWATYDDEYINKISEKQLLKEPNAYFLVY 695
+G W DD + S +L + AY L Y
Sbjct: 257 AQEGQWYKMDDAEVTASSITSVLSQ-QAYVLFY 288
>YER098w [O] KOG1864 Ubiquitin-specific protease
Length = 754
Score = 105 bits (262), Expect = 3e-22
Identities = 67/286 (23%), Positives = 126/286 (43%), Gaps = 52/286 (18%)
Query: 429 INPDKLINALEDINCMMSAWNQEDSHEYFMSLMSRLQEDSVPKGHKM----------TES 478
++P + + L+ N + + Q+D+HE+ L++ E +M ++
Sbjct: 412 VSPTEFVKILKKENVLFNTMMQQDAHEFLNFLLNDFSEYIQRNNPRMRFGPQKTDNSNDN 471
Query: 479 IIYDVFGGLLQQSVKCSNCGEISTTEQPIYDLSLHLKGRKTTDQDQNSVGQDNSIDNSVD 538
I D+F G L +KC C I++ ++P D + ++G + TD
Sbjct: 472 FITDLFKGTLTNRIKCLTCDNITSRDEPFLDFPIEVQGDEETD----------------- 514
Query: 539 QQQSSKRRFSIEKSIRDFFNPELIKRVDNKEGYTCEKCKKVTNALKSNKIIRAPETLVVH 598
I+K ++ + E++ V+ + C KC + A + + + P L +H
Sbjct: 515 ----------IQKMLKSYHQREMLNGVNK---FYCNKCYGLQEAERMVGLKQLPHILSLH 561
Query: 599 LKKFRFNGTSSSKMK--QAVSYPMFLDLTEYCHESISSLPVRYQLISVVVHEGRSLSSGH 656
LK+F+++ S +K + YP+ LD++ + S+ +Y+L VV+H G GH
Sbjct: 562 LKRFKYSEEQKSNIKLFNKILYPLTLDVSSTFNTSVYK---KYELSGVVIHMGSGPQHGH 618
Query: 657 YIAHCKQPDGSWATYDDEYINKISEKQLLK-------EPNAYFLVY 695
Y+ C+ W YDDE + I E+ +L+ + AY L Y
Sbjct: 619 YVCICRNEKFGWLLYDDETVESIKEETVLQFTGHPGDQTTAYVLFY 664
>YBL067c [O] KOG1864 Ubiquitin-specific protease
Length = 688
Score = 105 bits (262), Expect = 3e-22
Identities = 67/285 (23%), Positives = 130/285 (45%), Gaps = 58/285 (20%)
Query: 424 TKNTY----INPDKLINALEDINCMMSAWNQEDSHEYFMSLMSRLQE------------- 466
T+NTY ++P ++ L+ N + + +D+HE+F L++ L E
Sbjct: 401 TENTYLTGVVSPSSFVDVLKRENVLFNTTMHQDAHEFFNFLLNELSEYIERENKKIAASD 460
Query: 467 ---DSVPKGHKMTESIIYDVFGGLLQQSVKCSNCGEISTTEQPIYDLSLHLKGRKTTDQD 523
DS P K + I D+F G L +KC C I++ ++P D + ++G + TD
Sbjct: 461 INSDSEPSKSK---NFISDLFQGTLTNQIKCLTCDNITSRDEPFLDFPIEVQGDEETD-- 515
Query: 524 QNSVGQDNSIDNSVDQQQSSKRRFSIEKSIRDFFNPELIKRVDNKEGYTCEKCKKVTNAL 583
I++ ++ + E++ + + C++C + A
Sbjct: 516 -------------------------IQEILKSYHQREML---NGSNKFYCDECCGLQEAE 547
Query: 584 KSNKIIRAPETLVVHLKKFRFNGTSSSKMK--QAVSYPMFLDLTEYCHESISSLPVRYQL 641
+ + + P+TL +HLK+F+++ + +K + YP+ L++ C S + +Y+L
Sbjct: 548 RLVGLKQLPDTLTLHLKRFKYSEKQNCNIKLFNNIHYPLTLNV---CSSINSKVCQKYEL 604
Query: 642 ISVVVHEGRSLSSGHYIAHCKQPDGSWATYDDEYINKISEKQLLK 686
+VVH G GHY++ CK W +DDE + + E+ +L+
Sbjct: 605 AGIVVHMGGGPQHGHYVSLCKHEKFGWLLFDDETVEAVKEETVLE 649
>Hs21361712 [O] KOG1868 Ubiquitin C-terminal hydrolase
Length = 605
Score = 105 bits (261), Expect = 3e-22
Identities = 94/370 (25%), Positives = 162/370 (43%), Gaps = 64/370 (17%)
Query: 363 GLLNHGVTCYTNAAVQAMVHIPAIQHYLFQLL--RGNFKDTVKSNCVSMLLAETTMRMWS 420
GL N G TC+ N+ +Q + + ++ Y Q L R + + A+ +W+
Sbjct: 268 GLRNLGNTCFMNSILQCLSNTRELRDYCLQRLYMRDLHHGSNAHTALVEEFAKLIQTIWT 327
Query: 421 SDSTKNTYINPDKLINALEDINCMMSAWNQEDSHEYFMSLMSRLQE-------------- 466
S + N ++P + ++ +NQ+D+ E+ L+ L
Sbjct: 328 S--SPNDVVSPSEFKTQIQRYAPRFVGYNQQDAQEFLRFLLDGLHNEVNRVTLRPKSNPE 385
Query: 467 --DSVP---KGHKM-------TESIIYDVFGGLLQQSVKCSNCGEISTTEQPIYDLSLHL 514
D +P KG +M +S I D+F G L+ S+ C++CG ST P +DLSL +
Sbjct: 386 NLDHLPDDEKGRQMWRKYLEREDSRIGDLFVGQLKGSLTCTDCGYCSTVFDPFWDLSLPI 445
Query: 515 KGRKTTDQDQNSVGQDNSIDNSVDQQQSSKRRFSIEKSIRDFFNPELIKRVDNKEGYTCE 574
R + ++ +R F +++ D E TC
Sbjct: 446 AKRGYPE-------------------------VTLMDCMRLFTKEDVL---DGDEKPTCC 477
Query: 575 KCKKVTNALKSNKIIRAPETLVVHLKKFRFNGTSSSKMKQAVSYPM-FLDLTEYCHESIS 633
+C+ +K I R P+ LV+ LK+F + +SK+ V++P+ LDL E+ E+ +
Sbjct: 478 RCRGRKRCIKKFSIQRFPKILVLRLKRFSESRIRTSKLTTFVNFPLRDLDLREFASENTN 537
Query: 634 SLPVRYQLISVVVHEGRSLSSGHYIAHCKQP-DGSWATYDDEYINKISEKQLLKEPNAYF 692
Y L +V H G ++ GHY A+C+ P G W T++D + +S Q ++ +AY
Sbjct: 538 H--AVYNLYAVSNHSGTTM-GGHYTAYCRSPGTGEWHTFNDSSVTPMSSSQ-VRTSDAYL 593
Query: 693 LVYTRLTPKS 702
L Y +P S
Sbjct: 594 LFYELASPPS 603
>At5g46740 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 732
Score = 104 bits (260), Expect = 4e-22
Identities = 82/343 (23%), Positives = 144/343 (41%), Gaps = 46/343 (13%)
Query: 363 GLLNHGVTCYTNAAVQAMVHIPAIQHYLFQLLRGNFKDTVKSN-CVSMLLAETTMRMWSS 421
GL N G TC+ + +Q H + L + GN + CV L + S
Sbjct: 164 GLYNSGNTCFIASVLQCFTHTVPLIDSLRSFMYGNPCNCGNEKFCVMQALRDHIELALRS 223
Query: 422 DSTKNTYINPDKLINALEDINCMMSAWNQEDSHEYFMSLMSRLQEDSVPKGHKMTE---- 477
IN D+ + L + +QED+HE+ S + +L+ + +++
Sbjct: 224 SGYG---INIDRFRDNLTYFSSDFMINHQEDAHEFLQSFLDKLERCCLDPKNQLGSVSSQ 280
Query: 478 --SIIYDVFGGLLQQSVKCSNCGEISTTEQPIYDLSLHLKGRKTTDQDQNSVGQDNSIDN 535
+I+ +VFGG L ++ C NC +S T +P SL ++ T
Sbjct: 281 DLNIVDNVFGGGLMSTLCCCNCNSVSNTFEPSLGWSLEIEDVNT---------------- 324
Query: 536 SVDQQQSSKRRFSIEKSIRDFFNPELIKRVDNKEGYTCEKCKKVTNALKSNKIIRAPETL 595
+ K++ F E ++ + TC+ CK+ K + + P
Sbjct: 325 -------------LWKALESFTCVEKLE-----DQLTCDNCKEKVTKEKQLRFDKLPPVA 366
Query: 596 VVHLKKFRFNGTSSSKMKQAVSYPMFLDLTEYCHESIS-SLPVRYQLISVVVHEGRSLSS 654
HLK+F +G + K+ + +P+ LDL+ + + + RY L + V H G +
Sbjct: 367 TFHLKRFTNDGVTMEKIFDHIEFPLELDLSPFMSSNHDPEVSTRYHLYAFVEHIGIRATF 426
Query: 655 GHYIAHCKQPDGSWATYDDEYINKISEKQLLKEPNAYFLVYTR 697
GHY ++ + +W +DD + +ISE+++L P AY L Y R
Sbjct: 427 GHYSSYVRSAPETWHNFDDSKVTRISEERVLSRP-AYILFYAR 468
>Hs5730110 [O] KOG1867 Ubiquitin-specific protease
Length = 521
Score = 103 bits (257), Expect = 1e-21
Identities = 94/386 (24%), Positives = 160/386 (41%), Gaps = 63/386 (16%)
Query: 357 TQLKPRGLLNHGVTCYTNAAVQAMVHIPAIQHYLFQLLRGNFKD------------TVKS 404
T + GL N G TC+ NA +Q++ +I Y +L ++ +
Sbjct: 154 TAICATGLRNLGNTCFMNAILQSLSNIEQFCCYFKELPAVELRNGKTAGRRTYHTRSQGD 213
Query: 405 NCVSML--LAETTMRMWSSDSTKNTYINPDKLINALEDINCMMSAWNQEDSHEY------ 456
N VS++ +T +W T +P+ L + I + Q+D+HE+
Sbjct: 214 NNVSLVEEFRKTLCALWQGSQTA---FSPESLFYVVWKIMPNFRGYQQQDAHEFNALPFG 270
Query: 457 ------FMSLMSRLQEDSVPKGHKM-----------TESIIYDVFGGLLQQSVKCSNCGE 499
F ++ + + + +++ +FGG+LQ V C CG
Sbjct: 271 PPTLGNFRAVSTVFPAQQFCRRILLCLQVNKCCINGASTVVTAIFGGILQNEVNCLICGT 330
Query: 500 ISTTEQPIYDLSLHLKGRKTTDQDQNSVGQDNSIDNSVDQQQSSKRRFSIEKSIRDFFNP 559
S P DLSL + + + + +N Q + S+ +R F +
Sbjct: 331 ESRKFDPFLDLSLDIPSQFRSKRSKN---------------QENGPVCSLRDCLRSFTD- 374
Query: 560 ELIKRVDNKEGYTCEKCKKVTNALKSNKIIRAPETLVVHLKKFRFNGTSSSKMKQAVSYP 619
++ +D E Y C KCKK + K I + P+ L +HLK+F + +K+ V +P
Sbjct: 375 --LEELDETELYMCHKCKKKQKSTKKFWIQKLPKVLCLHLKRFHWTAYLRNKVDTYVEFP 432
Query: 620 M-FLDLTEYCHESISSLP--VRYQLISVVVHEGRSLSSGHYIAHCKQPDGSWATYDDEYI 676
+ LD+ Y E +S P Y L +VVVH G + SGHY A+ +G W ++D +
Sbjct: 433 LRGLDMKWYLLEPENSGPESCLYDLAAVVVHHGSGVGSGHYTAYATH-EGRWFHFNDSTV 491
Query: 677 NKISEKQLLKEPNAYFLVYTRLTPKS 702
E+ ++K AY L Y K+
Sbjct: 492 TLTDEETVVK-AKAYILFYVEHQAKA 516
>At2g24640 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 743
Score = 102 bits (254), Expect = 2e-21
Identities = 94/358 (26%), Positives = 157/358 (43%), Gaps = 54/358 (15%)
Query: 351 NWGSKLTQLKPRGLLNHGVTCYTNAAVQAMVHIPAIQHYLFQLLRGNFKDTVKSNCVSML 410
NW + + P GL N G +C+ N +Q + + YL + RG+ ++ +++
Sbjct: 218 NWDRPI--MAPCGLTNCGNSCFANVVLQCLSWTRPLVAYLLE--RGHKRECRRNDWC--F 271
Query: 411 LAETTMRMWSSDSTKNTYINPDKLINALEDINCMMSAWNQEDSHEYFMSLMSRLQ----- 465
L E + ++ ++ + +P +I+ L +I + QED+HE + +Q
Sbjct: 272 LCEFENHLDRANYSRFPF-SPMNIISRLPNIGGNLGYGRQEDAHELMRFAIDMMQSVCLD 330
Query: 466 ----EDSVPKGHKMTESIIYDVFGGLLQQSVKCSNCGEISTTEQPIYDLSLHLKGRKTTD 521
E VP + T I Y +FGGLLQ V+C+ C +S + + DL++ + G
Sbjct: 331 EFGGEKVVPPRAQETTLIQY-IFGGLLQSQVQCTACSNVSDQYENMMDLTVEIHGDAV-- 387
Query: 522 QDQNSVGQDNSIDNSVDQQQSSKRRFSIEKSIRDFFNPELIKRVDNKEGYTCEKCKKVTN 581
S+E+ + F E ++ DN Y C++C
Sbjct: 388 --------------------------SLEECLDQFTAKEWLQG-DNL--YKCDRCDDYVK 418
Query: 582 ALKSNKIIRAPETLVVHLKKFRFNGTSSSKMKQAVSYPMFLDLTEYCHESISSLPVRYQL 641
A K I AP L + LK RF G K+ + +S+P DL Y V Y+L
Sbjct: 419 ACKRLSIRCAPNILTIALK--RFQGGRFGKLNKRISFPETFDLGPYMSGGGEGSDV-YKL 475
Query: 642 ISVVVHEGRSLSS--GHYIAHCKQPDGSWATYDDEYINKISEKQLLKEPNAYFLVYTR 697
+V+VH +S GHYI + K G+W DD + K+ + +L + AY L+Y+R
Sbjct: 476 YAVIVHLDMLNASFFGHYICYVKDFRGNWYRIDDSEVEKVELEDVLSQ-RAYMLLYSR 532
>Hs12383078 [O] KOG1864 Ubiquitin-specific protease
Length = 366
Score = 101 bits (252), Expect = 4e-21
Identities = 87/344 (25%), Positives = 146/344 (42%), Gaps = 61/344 (17%)
Query: 363 GLLNHGVTCYTNAAVQAMVHIPAIQHYLFQLLRGNFKDTVKSNCVSMLLAETTMRMWSSD 422
GL+N G TCY N+ +QA+ + + K C++ L ++
Sbjct: 36 GLVNFGNTCYCNSVLQALYFCRPFRENVLAYKAQQKKKENLLTCLADLFHSI-----ATQ 90
Query: 423 STKNTYINPDKLINALEDINCMMSAWNQEDSHEYFMSLMSR----LQEDSVP-------K 471
K I P K I+ L N + + Q+D+HE+ L++ LQE+ K
Sbjct: 91 KKKVGVIPPKKFISRLRKENDLFDNYMQQDAHEFLNYLLNTIADILQEEKKQEKQNGKLK 150
Query: 472 GHKMTESI---------IYDVFGGLLQQSVKCSNCGEISTTEQPIYDLSLHLKGRKTTDQ 522
M E ++++F G L +C NC +S+ ++ DLS+ D
Sbjct: 151 NGNMNEPAENNKPELTWVHEIFQGTLTNETRCLNCETVSSKDEDFLDLSV--------DV 202
Query: 523 DQNSVGQDNSIDNSVDQQQSSKRRFSIEKSIRDFFNPELIKRVDNKEGYTCEKCKKVTNA 582
+QN+ SI +RDF N E + +++ Y CE C A
Sbjct: 203 EQNT---------------------SITHCLRDFSNTETLC---SEQKYYCETCCSKQEA 238
Query: 583 LKSNKIIRAPETLVVHLKKFRF--NGTSSSKMKQAVSYPMFLDLTEYCHESISSLPVRYQ 640
K ++ + P L +HLK+F++ +K+ V +P+ L L +++ +L Y
Sbjct: 239 QKRMRVKKLPMVLALHLKRFKYMEQLRRYTKLSYRVVFPLELRLFNTSSDAV-NLDRMYD 297
Query: 641 LISVVVHEGRSLSSGHYIAHCKQPDGSWATYDDEYINKISEKQL 684
L++VVVH G + GHYI K G W +DD+ + KI + +
Sbjct: 298 LVAVVVHCGSGPNRGHYITIVKS-HGFWLLFDDDIVEKIDAQAI 340
>At2g22310 [O] KOG1864 Ubiquitin-specific protease
Length = 365
Score = 101 bits (252), Expect = 4e-21
Identities = 85/352 (24%), Positives = 143/352 (40%), Gaps = 74/352 (21%)
Query: 363 GLLNHGVTCYTNAAVQAMVHIPAIQHYLFQLLRGNFKDTVKS--NCVSMLLAETTMRMWS 420
G N G TCY N+ +QA+ + L + N D ++ C++ L ++ S
Sbjct: 24 GFENFGNTCYCNSVLQALYFCAPFREQLLEHYANNKADAEENLLTCLADLFSQI-----S 78
Query: 421 SDSTKNTYINPDKLINALEDINCMMSAWNQEDSHEYFMSLMSRL-----QEDSVPKGHKM 475
S K I P + + L+ N + ++ +D+HE+ L++ L +E K
Sbjct: 79 SQKKKTGVIAPKRFVQRLKKQNELFRSYMHQDAHEFLNYLLNELVEILEKETQATKADNE 138
Query: 476 TESI------------------------IYDVFGGLLQQSVKCSNCGEISTTEQPIYDLS 511
T S ++ +F G+L +C C ++ ++ DLS
Sbjct: 139 TSSSPEKIANVLKAPLANGVHKEPIVTWVHKIFQGILTNETRCLRCETVTARDETFLDLS 198
Query: 512 LHLKGRKTTDQDQNSVGQDNSIDNSVDQQQSSKRRFSIEKSIRDFFNPELIKRVDNKEGY 571
L D +QNS SI +++F + E + D +
Sbjct: 199 L--------DIEQNS---------------------SITSCLKNFSSTETLHAEDK---F 226
Query: 572 TCEKCKKVTNALKSNKIIRAPETLVVHLKKFRFNGTSS--SKMKQAVSYPMFLDLTEYCH 629
C+KC + A K KI + P LV+HLK+F++ K+ V +P+ L L+
Sbjct: 227 FCDKCCSLQEAQKRMKIKKPPHILVIHLKRFKYMEQLGRYKKLSYRVVFPLELKLSNTVD 286
Query: 630 ESISSLPVRYQLISVVVHEGRSLSSGHYIAHCKQPDGSWATYDDEYINKISE 681
E + + Y L +VVVH G + GHY++ K W +DDE + I E
Sbjct: 287 EYVD---IEYSLFAVVVHVGSGPNHGHYVSLVKS-HNHWLFFDDESVEIIEE 334
>Hs20548613 [O] KOG1864 Ubiquitin-specific protease
Length = 370
Score = 97.4 bits (241), Expect = 7e-20
Identities = 87/345 (25%), Positives = 146/345 (42%), Gaps = 63/345 (18%)
Query: 363 GLLNHGVTCYTNAAVQAMVHIPAIQHYLFQLLRGNFKDTVKSNCVSMLLAETTMRMWSSD 422
GL+N G TCY N+ +QA+ + + K C++ L ++
Sbjct: 40 GLVNFGNTCYCNSVLQALYFCRPFREKVLAYKSQPRKKESLLTCLADLFHSI-----ATQ 94
Query: 423 STKNTYINPDKLINALEDINCMMSAWNQEDSHEYFMSLMSRL------------QEDSVP 470
K I P K I L N + + Q+D+HE+ L++ + Q +P
Sbjct: 95 KKKVGVIPPKKFITRLRKENELFDNYMQQDAHEFLNYLLNTIADILQEERKQEKQNGRLP 154
Query: 471 KGHKMTESI--------IYDVFGGLLQQSVKCSNCGEISTTEQPIYDLSLHLKGRKTTDQ 522
G+ E+ ++++F G L +C C IS+ ++ DLS+ D
Sbjct: 155 NGNIDNENNNSTPDPTWVHEIFQGTLTNETRCLTCETISSKDEDFLDLSV--------DV 206
Query: 523 DQNSVGQDNSIDNSVDQQQSSKRRFSIEKSIRDFFNPELIKRVDNKEGYTCEKCKKVTNA 582
+QN+ SI +R F N E + ++ Y CE+C+ A
Sbjct: 207 EQNT---------------------SITHCLRGFSNTETLC---SEYKYYCEECRSKQEA 242
Query: 583 LKSNKIIRAPETLVVHLKKFRFNGT--SSSKMKQAVSYPMFLDLTEYCHESISSLPVR-Y 639
K K+ + P L +HLK+F++ +K+ V +P+ L L ++ + P R Y
Sbjct: 243 HKRMKVKKLPMILALHLKRFKYMDQLHRYTKLSYRVVFPLELRLFNTSGDATN--PDRMY 300
Query: 640 QLISVVVHEGRSLSSGHYIAHCKQPDGSWATYDDEYINKISEKQL 684
L++VVVH G + GHYIA K D W +DD+ + KI + +
Sbjct: 301 DLVAVVVHCGSGPNRGHYIAIVKSHD-FWLLFDDDIVEKIDAQAI 344
>At4g17890_2 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 544
Score = 96.3 bits (238), Expect = 2e-19
Identities = 78/340 (22%), Positives = 145/340 (41%), Gaps = 46/340 (13%)
Query: 363 GLLNHGVTCYTNAAVQAMVH-IPAIQHYLFQLLRGNFKDTVKSNCVSMLLAETTMRMWSS 421
GL N G +C+ N+ Q H +P I+ L +F+ V +C + +
Sbjct: 26 GLWNLGNSCFLNSVFQCFTHTVPLIESLL------SFRYEVPCHCGNEFFCVIRAIRYHI 79
Query: 422 DST---KNTYINPDKLINALEDINCMMSAWNQEDSHEYFMSLMSRLQEDSVPKGHKMTES 478
++ + I P + L + + QED+HE+ + + +L+ + +
Sbjct: 80 EAALRPERCPIAPYFFFDNLNYFSPDFQRYQQEDAHEFLQAFLEKLEICGSDRTSFRGDI 139
Query: 479 IIYDVFGGLLQQSVKCSNCGEISTTEQPIYDLSLHLKGRKTTDQDQNSVGQDNSIDNSVD 538
DVF G L ++C NC +S T + LSL + +D +++G
Sbjct: 140 TSQDVFSGRLISGLRCCNCDYVSETYEKSVGLSLEI-------EDVDTLGS--------- 183
Query: 539 QQQSSKRRFSIEKSIRDFFNPELIKRVDNKEGYTCEKCKKVTNALKSNKIIRAPETLVVH 598
++E R ++++D E TC+ C + + K + + P H
Sbjct: 184 ---------ALESFTR-------VEKLD--EQLTCDNCNEKVSKEKQLLLDKLPLVATFH 225
Query: 599 LKKFRFNGTSSSKMKQAVSYPMFLDLTEYCHE-SISSLPVRYQLISVVVHEGRSLSSGHY 657
LK+F+ NG K+ + V P+ +DL Y + + +Y L ++V H G S++ GHY
Sbjct: 226 LKRFKNNGLYMEKIYKHVKIPLEIDLQPYMRNIQENEVSTKYHLYALVEHFGYSVAYGHY 285
Query: 658 IAHCKQPDGSWATYDDEYINKISEKQLLKEPNAYFLVYTR 697
++ + W +DD + +I E +L + ++Y L Y R
Sbjct: 286 SSYVRSAPKIWHHFDDSKVTRIDEDMVLSQ-DSYILFYAR 324
>At4g39910 [O] KOG1864 Ubiquitin-specific protease
Length = 371
Score = 95.1 bits (235), Expect = 3e-19
Identities = 81/353 (22%), Positives = 142/353 (39%), Gaps = 71/353 (20%)
Query: 363 GLLNHGVTCYTNAAVQAMVHIPAIQHYLFQLLRGNFKDTVKSNCVSMLLAETTMRMWSSD 422
G N G TCY N+ +QA+ + L + N + LA+ ++ SS
Sbjct: 24 GFENFGNTCYCNSVLQALYFCVPFREQLLEYYTSNKSVADAEENLMTCLADLFSQI-SSQ 82
Query: 423 STKNTYINPDKLINALEDINCMMSAWNQEDSHEYFMSLMSRLQE---------------- 466
K I P + + L+ N + ++ +D+HE+ L++ + +
Sbjct: 83 KKKTGVIAPKRFVQRLKKQNELFRSYMHQDAHEFLNYLLNEVVDILEKEAKATKTEHETS 142
Query: 467 -----DSVPKGHKMTESI-----------IYDVFGGLLQQSVKCSNCGEISTTEQPIYDL 510
+ + G K+ ++ ++++F G+L +C C ++ ++ DL
Sbjct: 143 SSSSPEKIANGLKVPQANGVVHKEPIVTWVHNIFQGILTNETRCLRCETVTARDETFLDL 202
Query: 511 SLHLKGRKTTDQDQNSVGQDNSIDNSVDQQQSSKRRFSIEKSIRDFFNPELIKRVDNKEG 570
SL D +QNS SI +++F + E + D
Sbjct: 203 SL--------DIEQNS---------------------SITSCLKNFSSTETLHAEDK--- 230
Query: 571 YTCEKCKKVTNALKSNKIIRAPETLVVHLKKFRFNGTSS--SKMKQAVSYPMFLDLTEYC 628
+ C+KC + A K KI + P LV+HLK+F++ K+ V +P+ L L+
Sbjct: 231 FFCDKCCSLQEAQKRMKIKKPPHILVIHLKRFKYIEQLGRYKKLSYRVVFPLELKLSNTV 290
Query: 629 HESISSLPVRYQLISVVVHEGRSLSSGHYIAHCKQPDGSWATYDDEYINKISE 681
V Y L +VVVH G + GHY++ K W +DDE + I E
Sbjct: 291 EPYAD---VEYSLFAVVVHVGSGPNHGHYVSLVKS-HNHWLFFDDENVEMIEE 339
>Hs18860907_1 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase
Length = 622
Score = 94.4 bits (233), Expect = 6e-19
Identities = 95/378 (25%), Positives = 149/378 (39%), Gaps = 77/378 (20%)
Query: 363 GLLNHGVTCYTNAAVQAMVHIPAIQHYLFQLLRGNFKDTVKSNCVS-------MLLAETT 415
GL N G TCY N +Q ++ L+ L D + + + + E
Sbjct: 90 GLTNLGATCYVNTFLQVWFLNLELRQALY-LCPSTCSDYMLGDGIQEEKDYEPQTICEHL 148
Query: 416 MRMWSSDSTKNT-YINPDKLINALEDINCMMSAWNQEDSHEYFMSLMSRLQEDSVPKGHK 474
+++ N YI+P + AL + Q+D+ E+ MS L++ + +
Sbjct: 149 QYLFALLQNSNRRYIDPSGFVKALG-----LDTGQQQDAQEFSKLFMSLLEDTLSKQKNP 203
Query: 475 MTESIIYDVFGGLLQQSVKCSNCGEISTTEQPIYDLSLHLKGRKTTDQDQNSVGQDNSID 534
+I+ F G C+ CG S Y+L L+++G K
Sbjct: 204 DVRNIVQQQFCGEYAYVTVCNQCGRESKLLSKFYELELNIQGHK---------------- 247
Query: 535 NSVDQQQSSKRRFSIEKSIRDFFNPELIKRVDNKEGYTCEKCKKVTNALKSNKIIRAPET 594
+ I +F E ++ DN+ Y CE C+ NA + +++ P T
Sbjct: 248 -------------QLTDCISEFLKEEKLEG-DNR--YFCENCQSKQNATRKIRLLSLPCT 291
Query: 595 LVVHLKKFRFNGTSSSKMK--QAVSYPMFLDLTEYCHESISSLPVRYQLISVVVHEGRSL 652
L + L +F F+ + K K + + LD+ Y S Y+L +V++H G S
Sbjct: 292 LNLQLMRFVFDRQTGHKKKLNTYIGFSEILDMEPYVEHKGGSYV--YELSAVLIHRGVSA 349
Query: 653 SSGHYIAHCKQP-DGSWATYDDEYINKISEKQL-------LKEP---------------- 688
SGHYIAH K P G W ++DE I K+ K+L L EP
Sbjct: 350 YSGHYIAHVKDPQSGEWYKFNDEDIEKMEGKKLQLGIEEDLAEPSKSQTRKPKCGKGTHC 409
Query: 689 --NAYFLVYTRLTPKSVP 704
NAY LVY RL + P
Sbjct: 410 SRNAYMLVY-RLQTQEKP 426
>Hs6912742 [O] KOG1868 Ubiquitin C-terminal hydrolase
Length = 565
Score = 93.2 bits (230), Expect = 1e-18
Identities = 94/381 (24%), Positives = 157/381 (40%), Gaps = 86/381 (22%)
Query: 363 GLLNHGVTCYTNAAVQAMVHIPAIQHYLFQLLRGNFKDTV----KSNCVSMLLAETTMRM 418
GL N G TC+ NA +Q + ++ + LR +F+ V ++ ++ A+ +
Sbjct: 213 GLRNLGNTCFLNAVLQCLSSTRPLRDFC---LRRDFRQEVPGGGRAQELTEAFADVIGAL 269
Query: 419 WSSDSTKNTYINPDKLINALEDINCMMSAWNQEDSHEYFMSLMSRLQEDSVPKGHKMT-- 476
W DS + +NP + + S ++Q+D+ E+ LM RL + +G +
Sbjct: 270 WHPDSCEA--VNPTRFRAVFQKYVPSFSGYSQQDAQEFLKLLMERLHLEINRRGRRAPPI 327
Query: 477 ---------------------------------------ESIIYDVFGGLLQQSVKCSNC 497
+S I D+F G L+ +KC C
Sbjct: 328 LANGPVPSPPRRGGALLEEPELSDDDRANLMWKRYLEREDSKIVDLFVGQLKSCLKCQAC 387
Query: 498 GEISTTEQPIYDLSLHLKGRKTTDQDQNSVGQDNSIDNSVDQQQSSKRRFSIEK-SIRDF 556
G STT + DLSL + K+ F+ K S+RD
Sbjct: 388 GYRSTTFEVFCDLSLPIP----------------------------KKGFAGGKVSLRDC 419
Query: 557 FNP-ELIKRVDNKEGYTCEKCKKVTNALKSNKIIRAPETLVVHLKKFRFNGTSSSKMKQA 615
FN + ++++ C++C++ T + K + R P LV+HL +F + S K
Sbjct: 420 FNLFTKEEELESENAPVCDRCRQKTRSTKKLTVQRFPRILVLHLNRFSASRGSIKKSSVG 479
Query: 616 VSYPM-FLDLTEYCHESISSLPVRYQLISVVVHEGRSLSSGHYIAHCKQPDGSWATYDDE 674
V +P+ L L ++ + S PV YQL ++ H G S+ GHY A C+ G W Y+D
Sbjct: 480 VDFPLQRLSLGDFASDKAGS-PV-YQLYALCNHSG-SVHYGHYTALCRCQTG-WHVYNDS 535
Query: 675 YINKISEKQLLKEPNAYFLVY 695
++ +SE Q+ Y L Y
Sbjct: 536 RVSPVSENQVASS-EGYVLFY 555
>7303210 [O] KOG1870 Ubiquitin C-terminal hydrolase
Length = 857
Score = 92.8 bits (229), Expect = 2e-18
Identities = 66/239 (27%), Positives = 119/239 (49%), Gaps = 18/239 (7%)
Query: 478 SIIYDVFGGLLQQSVKCSNCGEISTTEQPIYDLSLHLKGRKTTDQDQNSVGQDNSIDNSV 537
SII DVF G L SV+C C + + + L +T+ + G + + N +
Sbjct: 217 SIISDVFDGKLLSSVQCLTCDRVLSVQS--------LNAAETSARTNE--GWLSWMWNML 266
Query: 538 DQQQSSKRRFSIEKSIRDFFNPELIKRVDNKEGYTCEKCKKVTNALKSNKIIRAPETLVV 597
+ ++ + FF+ + +K DN Y+CE+C K+ +K ++++ PE L +
Sbjct: 267 -RSWIYGPSVTLYDCMASFFSADELKG-DNM--YSCERCNKLRTGIKYSRVLTLPEVLCI 322
Query: 598 HLKKFRFNGTSSSKMKQAVSYPM-FLDLTEYCHESISSLPVRYQLISVVVHEGRSLSSGH 656
HLK+FR + + SSK+ V +P+ D+ Y H+ S Y L SV+ H G ++ GH
Sbjct: 323 HLKRFRNDLSYSSKISSDVYFPLEGFDMRPYIHKDCKSEVAIYNLSSVICHHG-TVGGGH 381
Query: 657 YIAHCKQP-DGSWATYDDEYINKISEKQLLKEPNAYFLVYTRLTPKSVPLSSQSSNKST 714
Y + +G W +DD+++ ++S +L++ AY L Y + P+ + ++ ST
Sbjct: 382 YTCFARNTLNGKWYEFDDQFVTEVS-SELVQSCQAYVLFYHKHNPQMKLVRDEAMTLST 439
>SPBC1703.12 [O] KOG1864 Ubiquitin-specific protease
Length = 585
Score = 92.0 bits (227), Expect = 3e-18
Identities = 69/296 (23%), Positives = 122/296 (40%), Gaps = 44/296 (14%)
Query: 430 NPDKLINALEDINCMMSAWNQEDSHEYFMSLMSRLQE--DSVPKGHK--MTESIIYDVFG 485
+P++ I L N + Q+D+HE+F L++ + E D H M ++ +F
Sbjct: 176 SPERFIQVLRRDNEAFRSTQQQDAHEFFNFLLNSVTETLDEYYGNHSDVMHPKWVHSLFE 235
Query: 486 GLLQQSVKCSNCGEISTTEQPIYDLSLHLKGRKTTDQDQNSVGQDNSIDNSVDQQQSSKR 545
G L KC C I++ ++ DLS+ ++
Sbjct: 236 GTLTSETKCLTCENITSRDESFLDLSIDIENHT--------------------------- 268
Query: 546 RFSIEKSIRDFFNPELIKRVDNKEGYTCEKCKKVTNALKSNKIIRAPETLVVHLKKFRFN 605
S+ +R F E++ +K + C+ CK + A K KI + P+ L +HLK+F++N
Sbjct: 269 --SVTSCLRSFSASEMLS---SKNKFHCDVCKSLQEAEKRMKIKKLPKILSLHLKRFKYN 323
Query: 606 GTSSSKMKQAVSYPMFLDLTEY-CHESISSLPVRYQLISVVVHEGRSLSSGHYIAHCKQP 664
T K + ++ + E + Y L SV+VH G GHY++ +
Sbjct: 324 ETQEGHDKLFYTIVFTNEMRLFTTTEDAENAERMYYLSSVIVHVGGGPHRGHYVSIVRTK 383
Query: 665 DGSWATYDDEYINKISEKQLLK-------EPNAYFLVYTRLTPKSVPLSSQSSNKS 713
W +DDE + ++E L + + AY L YT + +S + +S
Sbjct: 384 TYGWVLFDDENVTPVNENYLQRFFGDQPGQATAYVLFYTAADEEDDDVSEVDTKES 439
>Hs14149817 [O] KOG1867 Ubiquitin-specific protease
Length = 712
Score = 91.3 bits (225), Expect = 5e-18
Identities = 84/338 (24%), Positives = 146/338 (42%), Gaps = 65/338 (19%)
Query: 418 MWSSDSTKNTYINPDKLINALEDINCMMSAWNQEDSHEYFMSLMSRLQED------SVP- 470
MWS K ++P +++++ + + Q+D+ E+ L+ ++Q + S+P
Sbjct: 392 MWSG---KWALVSPFAMLHSVWRLIPAFRGYAQQDAQEFLCELLDKIQRELETTGTSLPA 448
Query: 471 -------KGHKMTESIIYDVFGGLLQQSVKCSNCGEISTTEQPIYDLSLHLKGRKTTDQD 523
K K +++ ++F G L V C C S T +P +DLSL R
Sbjct: 449 LIPTSQRKLIKQVLNVVNNIFHGQLLSQVTCLACDNKSNTIEPFWDLSLEFPERYQCS-- 506
Query: 524 QNSVGQDNSIDNSVDQQQSSKRRFSIEKSIRDFFNPELIKRVDNKEGYTCEKCKK----- 578
G+D + + + +K F E ++ + Y C++C
Sbjct: 507 ----GKDIASQPCLVTEMLAK-----------FTETEALEG----KIYVCDQCNSKRRRF 547
Query: 579 ------VTNALKSNKIIRAPETLVVHLKKFRFNGTSS-SKMKQAVSYPMFLDLTEYC-HE 630
+T A K I P+ L +HLK+FR++G ++ K+ V + L++ YC E
Sbjct: 548 SSKPVVLTEAQKQLMICHLPQVLRLHLKRFRWSGRNNREKIGVHVGFEEILNMEPYCCRE 607
Query: 631 SISSLPVR---YQLISVVVHEGRSLSSGHYIAHCKQPDGS-WATYDDEYINKISEKQLLK 686
++ SL Y L +VV+H G+ SGHY A+C +G W +D ++ + ++ K
Sbjct: 608 TLKSLRPECFIYDLSAVVMHHGKGFGSGHYTAYCYNSEGGFWVHCNDSKLSMCTMDEVCK 667
Query: 687 EPNAYFLVYT---------RLTPKSVPLSSQSSNKSTD 715
AY L YT +L P + L SQ N+ D
Sbjct: 668 -AQAYILFYTQRVTENGHSKLLPPELLLGSQHPNEDAD 704
>HsM7706755 [O] KOG1868 Ubiquitin C-terminal hydrolase
Length = 381
Score = 90.5 bits (223), Expect = 8e-18
Identities = 93/381 (24%), Positives = 156/381 (40%), Gaps = 86/381 (22%)
Query: 363 GLLNHGVTCYTNAAVQAMVHIPAIQHYLFQLLRGNFKDTV----KSNCVSMLLAETTMRM 418
GL N G TC+ NA +Q + ++ + LR +F+ V ++ ++ A+ +
Sbjct: 29 GLRNLGNTCFLNAVLQCLSSTRPLRDFC---LRRDFRQEVPGGGRAQELTEAFADVIGAL 85
Query: 419 WSSDSTKNTYINPDKLINALEDINCMMSAWNQEDSHEYFMSLMSRLQEDSVPKGHKMT-- 476
W DS + +NP + + S ++Q+D+ E+ LM RL + +G +
Sbjct: 86 WHLDSCEA--VNPTRFRAVFQKYVPSFSGYSQQDAQEFLKLLMERLHLEINRRGRRAPPI 143
Query: 477 ---------------------------------------ESIIYDVFGGLLQQSVKCSNC 497
+S I D+F G L+ +KC C
Sbjct: 144 LANGPVPSPPRRGGALLEEPELSDDDRANLMWKRYLEREDSKIVDLFVGQLKSCLKCQAC 203
Query: 498 GEISTTEQPIYDLSLHLKGRKTTDQDQNSVGQDNSIDNSVDQQQSSKRRFSIEKS-IRDF 556
G STT + DLSL + K+ F+ K +RD
Sbjct: 204 GYRSTTFEVFCDLSLPIP----------------------------KKGFAGGKVFLRDC 235
Query: 557 FNP-ELIKRVDNKEGYTCEKCKKVTNALKSNKIIRAPETLVVHLKKFRFNGTSSSKMKQA 615
FN + ++++ C++C++ T + K + R P LV+HL +F + S K
Sbjct: 236 FNLFTKEEELESENAPVCDRCRQKTRSTKKLTVQRFPRILVLHLNRFSASRGSIKKSSVG 295
Query: 616 VSYPM-FLDLTEYCHESISSLPVRYQLISVVVHEGRSLSSGHYIAHCKQPDGSWATYDDE 674
V +P+ L L ++ + S PV YQL ++ H G S+ GHY A C+ G W Y+D
Sbjct: 296 VDFPLQRLSLGDFASDKAGS-PV-YQLYALCNHSG-SVHYGHYTALCRCQTG-WHVYNDS 351
Query: 675 YINKISEKQLLKEPNAYFLVY 695
++ +SE Q+ Y L Y
Sbjct: 352 RVSPVSENQVASS-EGYVLFY 371
>YDR069c [O] KOG1868 Ubiquitin C-terminal hydrolase
Length = 926
Score = 90.1 bits (222), Expect = 1e-17
Identities = 96/396 (24%), Positives = 148/396 (37%), Gaps = 95/396 (23%)
Query: 363 GLLNHGVTCYTNAAVQAMVHIPAIQHYLFQL-LRGNFKDTVKSNC-------VSMLLAET 414
GL N G +CY N +Q ++ H L Q+ L ++ + N ++ A
Sbjct: 563 GLENLGNSCYMNCIIQCILGT----HELTQIFLDDSYAKHININSKLGSKGILAKYFARL 618
Query: 415 TMRMWSS--DSTKNTYINPDKLINALEDINCMMSAWNQEDSHEYFMSLMSRLQED----- 467
M+ D +K I+P K A +N + +Q+D E+ L+ L ED
Sbjct: 619 VHMMYKEQVDGSKKISISPIKFKLACGSVNSLFKTASQQDCQEFCQFLLDGLHEDLNQCG 678
Query: 468 SVPKGHKMTE---------------------------SIIYDVFGGLLQQSVKCSNCGEI 500
S P ++++ S+I D+F G +KC C
Sbjct: 679 SNPPLKELSQEAEARREKLSLRIASSIEWERFLTTDFSVIVDLFQGQYASRLKCKVCSHT 738
Query: 501 STTEQPIYDLSLHLKGRKTTDQDQNSVGQDNSIDNSVDQQQSSKRRFSIEKSIRDFFNPE 560
STT QP LS+ + +++S+ +IE R+F E
Sbjct: 739 STTYQPFTVLSIPI------------------------PKKNSRNNITIEDCFREFTKCE 774
Query: 561 LIKRVDNKEGYTCEKCKKVTNALKSNKIIRAPETLVVHLKKFRFNGTSSSKMKQAVSYPM 620
++ E + C C+K + K I R P L+VHLK+F +K V YP
Sbjct: 775 ---NLEVDEQWLCPHCEKRQPSTKQLTITRLPRNLIVHLKRF---DNLLNKNNDFVIYPF 828
Query: 621 FLDLTEYCHESISSL-----------------PVRYQLISVVVHEGRSLSSGHYIAHCKQ 663
LDLT + + P +Y+L V H G +L GHY A+ K+
Sbjct: 829 LLDLTPFWANDFDGVFPPGVNDDELPIRGQIPPFKYELYGVACHFG-TLYGGHYTAYVKK 887
Query: 664 P-DGSWATYDDEYINKISEKQLLKEPNAYFLVYTRL 698
W +DD + K NAY L Y R+
Sbjct: 888 GLKKGWLYFDDTKYKPVKNKADAINSNAYVLFYHRV 923
>Hs22044555 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 489
Score = 88.6 bits (218), Expect = 3e-17
Identities = 76/333 (22%), Positives = 130/333 (38%), Gaps = 82/333 (24%)
Query: 363 GLLNHGVTCYTNAAVQAMVHIPAIQHYLFQLLRGNFKDTVKSNCVSMLLAETTMRMWSSD 422
GL N G TCY NA++Q + + P + +Y+ L T + ML
Sbjct: 81 GLQNMGNTCYVNASLQCLTYTPPLANYM---LSREHSQTCHRHKGCML------------ 125
Query: 423 STKNTYINPDKLINALEDINCMMSAWNQEDSHEYFMSLMSRLQEDSVPKGHKMTESIIYD 482
C M A + L H ++I+
Sbjct: 126 --------------------CTMQA-----------HITRALHNPGHVDHHSKDTTLIHQ 154
Query: 483 VFGGLLQQSVKCSNCGEISTTEQPIYDLSLHLKGRKTTDQDQNSVGQDNSIDNSVDQQQS 542
+FGG + +KC +C IS T P D++L ++ +
Sbjct: 155 IFGGYWRSQIKCLHCHRISDTFDPYLDIALDIQAAQ------------------------ 190
Query: 543 SKRRFSIEKSIRDFFNPELIKRVDNKEGYTCEKCKKVTNALKSNKIIRAPETLVVHLKKF 602
S+++++ PE ++ + Y C C + A K+ + + + L++ LK
Sbjct: 191 -----SVQQALEQLVKPE---ELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLK-- 240
Query: 603 RFNGTSSSKMKQAVSYPMFLDLTEYCHESISSLPVRYQLISVVVHEGRSLSSGHYIAHCK 662
RF+ + +K+ + V YP LD+ Y + + P+ Y L +V+VH G S +GHY ++ K
Sbjct: 241 RFSDVTGNKIAKNVQYPECLDMQPYMSQQNTG-PLVYVLYAVLVHAGWSCHNGHYFSYVK 299
Query: 663 QPDGSWATYDDEYINKISEKQLLKEPNAYFLVY 695
+G W DD + S +L + AY L Y
Sbjct: 300 AQEGQWYKMDDAEVTASSITSVLTQ-QAYVLFY 331
>CE13964 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 376
Score = 87.4 bits (215), Expect = 7e-17
Identities = 79/350 (22%), Positives = 148/350 (41%), Gaps = 68/350 (19%)
Query: 351 NWGSKLTQLKPRGLLNHGVTCYTNAAVQAMVHIPAIQHYLFQLLRGNFKDTVKSNCVSML 410
NW +G+ N + CY + VQ + H+PAI + N L
Sbjct: 78 NWSELRENYPEKGIQNPSIYCYAISCVQLLSHVPAIVRII--------------NAKIQL 123
Query: 411 LAETTMRMWSSDSTKNTYINPDKLINALEDINCMMSAWNQEDSHEYFMSLMSRLQEDSVP 470
++ T R S K + LE +S QED+H+ ++++ +L + SV
Sbjct: 124 VSAATGRKTSF-----------KAMAMLE-----LSIGRQEDAHDALLAILGKLDKISVQ 167
Query: 471 KGHKMT-ESIIYDVFGGLLQQSVKCSNCGEISTTEQPIYDLSLHLKGRKTTDQDQNSVGQ 529
++ + D+FG ++ V+C C K + N+V
Sbjct: 168 SNPRLKGRKVADDLFGYSIRNEVQCPGCKN------------------KHVYYEHNTVMT 209
Query: 530 DNSIDNSVDQQQSSKRRFSIEKSIRDFFNPELIKRVDNKEGYTCEKCKKVTNALKSNKII 589
+ ++ S + SI++ ++ F I GY C KCKK ++A ++
Sbjct: 210 VRML-----RKDPSGKSHSIKELMQALFTESKIF------GYNCSKCKKKSDAPVKPTLL 258
Query: 590 RAPETLVVHLKKFRFNGTSSSKMKQAVSYPMFLDLTEYCHESISSLPVRYQLISVVVHEG 649
RAP+ L++H+ +F F+G K+ + V+ LD+T S++ Y+L V+H G
Sbjct: 259 RAPQILLMHISRFSFDGW-GKKISRPVTLNETLDVTSMATAGASTV---YKLCGAVIHGG 314
Query: 650 RSLSSGHY--IAHCKQPDGSWATYDDEYINKISEKQLLKEPNAYFLVYTR 697
+L GHY +A ++ + + T +D +++ + + +Y ++Y R
Sbjct: 315 TTLDYGHYWCVARSRKREEQFVTLNDSSVSQHTNPR--DALQSYIVLYRR 362
>At5g57990 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 829
Score = 85.1 bits (209), Expect = 4e-16
Identities = 85/349 (24%), Positives = 135/349 (38%), Gaps = 71/349 (20%)
Query: 363 GLLNHGVTCYTNAAVQAMVHIPAIQHYLFQLLRGNFKDTVKSNCVSMLLAETTMRMWSSD 422
GL N G TC+ N+ +Q + + + L + V C L + ++
Sbjct: 108 GLQNLGNTCFLNSVLQCLTYTEPLAATLQTAAHQKYCH-VAGFCA---LCAIQKHVRTAR 163
Query: 423 STKNTYINPDKLINALEDINCMMSAWNQEDSHEYFMSLMSRLQEDSVPKGHKMTESIIYD 482
+ P L++ L I+ QED+HEY ++L+ +
Sbjct: 164 QANGRILAPKDLVSNLRCISRNFRNCRQEDAHEYMINLLECMH----------------- 206
Query: 483 VFGGLLQQSVKCSNCGEISTTEQPIYDLSLHLKGRKTTDQDQNSVGQDNSIDNSVDQQQS 542
KCS + + Y SL K S+ Q++
Sbjct: 207 ----------KCSLPSGVPSESSDAYRRSLVHK----------------IFGGSLRSQRA 240
Query: 543 SKRRFSIEKSIRDFFNPELIKRVDN-KEGYTCEKCKKVTNALKSNKIIRAPETLVVHLKK 601
R ++E +DN + Y CE+CK+ A K + +AP L VHLK
Sbjct: 241 LSRFTAVEL-------------LDNGAKVYQCERCKQKVKAKKQLTVSKAPYVLTVHLK- 286
Query: 602 FRFNGTSSSKMKQAVSYPMFLDLTEYC---HESISSLPVRYQLISVVVHEGRSLSSGHYI 658
RF S K+ + V + +D+ + HE ++Y L V+VH GRS SGHY
Sbjct: 287 -RFEAHRSEKIDRKVDFTSAIDMKPFVSGPHEG----NLKYTLYGVLVHYGRSSHSGHYA 341
Query: 659 AHCKQPDGSWATYDDEYINKISEKQLLKEPNAYFLVYTRLTPKSVPLSS 707
+ G W + DD + ++SEK + + AY L Y R +VP +S
Sbjct: 342 CFVRTSSGMWYSLDDNRVVQVSEKTVFNQ-KAYMLFYVRDRQNAVPKNS 389
>7292013_2 [O] KOG1871 Ubiquitin-specific protease
Length = 414
Score = 85.1 bits (209), Expect = 4e-16
Identities = 87/400 (21%), Positives = 165/400 (40%), Gaps = 55/400 (13%)
Query: 359 LKPRGLLNHGVTCYTNAAVQAMVHIPAIQHYLFQLLR-GNFKDTVKSNCVSMLLAETT-- 415
L+PRGL N CY N+ +QA++ + L + + VK+ V+ +++ T
Sbjct: 4 LRPRGLTNRSNYCYINSILQALLGCSPFYNLLRSIPKQAAVLSEVKTPTVNAMMSFMTNF 63
Query: 416 -------------MRMWSSDSTKNTYINPDKLINALEDINCMMSAWN----------QED 452
+ S K+ ++ D + + + WN QED
Sbjct: 64 SSLPSGLRLRLNNLNKGSQSKGKDDFVGSDLQCDMAFEPTEIYKLWNDSREEHVEGRQED 123
Query: 453 SHEYFMSLMSRLQEDSV--------PKGHKMTESIIYDVFGGLLQQSVKCSNCGEISTTE 504
+ E+ ++++L ++ + P + + GG + Q + C+N + S T
Sbjct: 124 AEEFLGYVLNKLNDEMLEVIKLIDKPTPQQNGQEPAEPEDGGDVWQMI-CNNRNKGSVTR 182
Query: 505 Q------PIYDLSLHLKGRKTTDQDQNSVGQDNSIDNSVDQQQSSKRRFSIEKSIRDFFN 558
Q P+ D+ +G + + + I Q + ++ S+++++
Sbjct: 183 QTDFGRTPVSDI---FRGELRSRLQREGEHSTDVIQPFFTLQLNIEKAASVKEAL----- 234
Query: 559 PELIKRVDNKEGYTCEKCKKVTNALKSNKIIRAPETLVVHLKKFRFNGTSSSKMKQAVSY 618
E++ D EG T K K+ A + + + P L++HLK F + +K+ + V +
Sbjct: 235 -EILVGRDQLEGVTGSKTKQEVVAWQQMTLEKLPVVLILHLKYFDYRSDGCTKILKKVDF 293
Query: 619 PMFL--DLTEYCHESISSLPVRYQLISVVVHEGRSLSSGHYIAHCKQPD-GSWATYDDEY 675
P+ L D + S Y+L +VV H+G+ S GHYI SW YDD
Sbjct: 294 PVELKIDAKILGSKKTSQKQRAYRLFAVVYHDGKEASKGHYITDVFHTGYSSWLRYDDSS 353
Query: 676 INKISEKQLLK--EPNAYFLVYTRLTPKSVPLSSQSSNKS 713
+ +SEK +L+ P +L+Y R + P Q+ ++
Sbjct: 354 VKPVSEKHVLQPHTPRVPYLLYYRRSDTLPPQQQQTQQQN 393
>CE26241 [O] KOG1867 Ubiquitin-specific protease
Length = 664
Score = 84.3 bits (207), Expect = 6e-16
Identities = 87/355 (24%), Positives = 134/355 (37%), Gaps = 81/355 (22%)
Query: 360 KPRGLLNHGVTCYTNAAVQAMVHIPAIQHYLFQLLRGNFKDTV------KSNCVSMLLAE 413
+PRG+ N G TC+ NA +QA+ I + Y+ L + +D + K+ L +
Sbjct: 376 RPRGMRNVGNTCFMNAVLQALASISEFREYIMSL--SSLEDYIHDEKEPKNGGNYCYLTD 433
Query: 414 TTMRMWSSDSTKN--TYINPDKLINALEDINCMMSAWNQEDSHEYFMSLMSRLQED---- 467
++ S S ++ P++ A + + Q DSHE+ M L +
Sbjct: 434 EYRKLLISQSARSFREPTAPNEFREAFISVCPRFRGFRQHDSHEFMRYFMDSLHTEMRKC 493
Query: 468 -SVPKGHKMTESIIYDVFGGLLQQSVKCSNCGEISTTEQPIYDLSLHLKGRKTTDQDQNS 526
+P + I F G LQ SV C C S DLSL +
Sbjct: 494 RKLPGMPDDKHTPISKYFEGTLQSSVICQTCRNCSNKIDEFMDLSLDIPA---------- 543
Query: 527 VGQDNSIDNSVDQQQSSKRRFSIEKSIRDFFNPELIKRVDNKEGYTCEKCKKVTNALKSN 586
Q+ +SK R S + FF E++++ + E C KC
Sbjct: 544 ------------QRNASKVRLS--DCLSTFFKLEMLEKGEKPE---CAKC---------- 576
Query: 587 KIIRAPETLVVHLKKFRFNGTSSSKMKQAVSYPMFLDLTEYCHESISSLPVRYQLISVVV 646
K KQ S MF+ + P Y L S++V
Sbjct: 577 ------------------------KTKQTCSKQMFI---RKLPQDSDEAPCTYSLQSIIV 609
Query: 647 HEGRSLSSGHYIAHCKQPDGSWATYDDEYINKISEKQLLKEPNAYFLVYTRLTPK 701
H G SGHYIA K+ +G W +DD + + E + K+ AY L+YT++ K
Sbjct: 610 HIGYGCGSGHYIAFGKR-NGRWFQFDDTVVKGVDEAHVSKQ-KAYVLLYTKIIRK 662
>YER144c [O] KOG1868 Ubiquitin C-terminal hydrolase
Length = 805
Score = 82.4 bits (202), Expect = 2e-15
Identities = 103/392 (26%), Positives = 143/392 (36%), Gaps = 90/392 (22%)
Query: 363 GLLNHGVTCYTNAAVQAMVHIPAIQHYLFQLLRGNFKDTVKSNCVSMLLAET------TM 416
GL N G CY N +Q +V + NF + S LLA+ M
Sbjct: 447 GLENIGNCCYMNCILQCLVGTHDLVRMFLDNTYLNFINFDSSRGSKGLLAKNFAILVNNM 506
Query: 417 RMWSSDSTKNTYINPDKLINALE---DINCMMSAWNQEDSHEYFMSLMSRLQEDSVPKGH 473
+ + N P + I + IN M S Q+D E+ L+ L ED G
Sbjct: 507 HRHGAFTPPNVRTIPVQTIQFKKICGHINPMYSDSMQQDCQEFCQFLLDGLHEDLNQNGS 566
Query: 474 K-------------------------------MTE-SIIYDVFGGLLQQSVKCSNCGEIS 501
K +T+ S I D+F G ++C C S
Sbjct: 567 KKHLKQLSDEEERMREKMSIRKASALEWERFLLTDFSAIIDLFQGQYASRLQCQVCEHTS 626
Query: 502 TTEQPIYDLSLHLKGRKTTDQDQNSVGQDNSIDNSVDQQQSSKRRFSIEKSIRDFFNPEL 561
TT Q LS+ + KT + I R+F E
Sbjct: 627 TTYQTFSVLSVPVPRVKTCN---------------------------ILDCFREFTKCE- 658
Query: 562 IKRVDNKEGYTCEKCKKVTNALKSNKIIRAPETLVVHLKKFRFNGTSSSKMKQAVSYPMF 621
R+ E ++C KC K + K KI R P+ L+++LK+F +K V YP
Sbjct: 659 --RLGVDEQWSCPKCLKKQPSTKQLKITRLPKKLIINLKRF---DNQMNKNNVFVQYPYS 713
Query: 622 LDLTEYC-----HESISSL---------PVRYQLISVVVHEGRSLSSGHYIAHC-KQPDG 666
LDLT Y HE+I + P RY+L V H G SL GHY ++ K P
Sbjct: 714 LDLTPYWARDFNHEAIVNEDIPTRGQVPPFRYRLYGVACHSG-SLYGGHYTSYVYKGPKK 772
Query: 667 SWATYDDEYINKISEKQLLKEPNAYFLVYTRL 698
W +DD I+ P+AY L Y R+
Sbjct: 773 GWYFFDDSLYRPITFSTEFITPSAYVLFYERI 804
>At2g40930 [O] KOG1870 Ubiquitin C-terminal hydrolase
Length = 914
Score = 82.0 bits (201), Expect = 3e-15
Identities = 49/131 (37%), Positives = 73/131 (55%), Gaps = 4/131 (3%)
Query: 569 EGYTCEKCKKVTNALKSNKIIRAPETLVVHLKKFRFNGTSSSKMKQAVSYPMF-LDLTEY 627
E + C +C + A K + R PE LV+HLK+F ++ + K++ V++P+ LDLT+Y
Sbjct: 777 EMWFCPQCNERRQASKKLDLWRLPEVLVIHLKRFSYSRSMKHKLETFVNFPIHDLDLTKY 836
Query: 628 CHESISSLPVRYQLISVVVHEGRSLSSGHYIAHCKQPDGS-WATYDDEYINKISEKQLLK 686
S P Y+L ++ H G + SGHY AH K D S W +DD +I+ I+E +K
Sbjct: 837 VANKNLSQPQLYELYALTNHYG-GMGSGHYTAHIKLLDDSRWYNFDDSHISHINEDD-VK 894
Query: 687 EPNAYFLVYTR 697
AY L Y R
Sbjct: 895 SGAAYVLFYRR 905
>Hs21265129 [O] KOG1868 Ubiquitin C-terminal hydrolase
Length = 551
Score = 80.9 bits (198), Expect = 7e-15
Identities = 86/380 (22%), Positives = 145/380 (37%), Gaps = 98/380 (25%)
Query: 363 GLLNHGVTCYTNAAVQAMVHIPAIQHYLFQLLRGNFKDTV----KSNCVSMLLAETTMRM 418
GL N G TC+ NA +Q + ++ + LR +F+ V ++ ++ A+ +
Sbjct: 213 GLRNLGNTCFLNAVLQCLSSTRPLRDFC---LRRDFRQEVPGGGRAQELTEAFADVIGAL 269
Query: 419 WSSDSTKNTYINPDKLINALEDINCMMSAWNQEDSHEYFMSLMSRLQEDSVPKGHKMT-- 476
W DS + +NP + + S ++Q+D+ E+ LM RL + +G +
Sbjct: 270 WHPDSCEA--VNPTRFRAVFQKYVPSFSGYSQQDAQEFLKLLMERLHLEINRRGRRAPPI 327
Query: 477 ---------------------------------------ESIIYDVFGGLLQQSVKCSNC 497
+S I D+F G L+ +KC C
Sbjct: 328 LANGPVPSPPRRGGALLEEPELSDDDRANLMWKRYLEREDSKIVDLFVGQLKSCLKCQAC 387
Query: 498 GEISTTEQPIYDLSLHLKGRKTTDQDQNSVGQDNSIDNSVDQQQSSKRRFSIEK-SIRDF 556
G STT + DLSL + K+ F+ K S+RD
Sbjct: 388 GYRSTTFEVFCDLSLPIP----------------------------KKGFAGGKVSLRDC 419
Query: 557 FNP-ELIKRVDNKEGYTCEKCKKVTNALKSNKIIRAPETLVVHLKKFRFNGTSSSKMKQA 615
FN + ++++ C++C++ T + K + R P LV+HL +F + S K
Sbjct: 420 FNLFTKEEELESENAPVCDRCRQKTRSTKKLTVQRFPRILVLHLNRFSASRGSIKKSSVG 479
Query: 616 VSYPMFLDLTEYCHESISSLPVRYQLISVVVHEGRSLSSGHYIAHCKQPDGSWATYDDEY 675
V +P+ R L + S+ GHY A C+ G W Y+D
Sbjct: 480 VDFPL----------------QRLSLGDFASDKAGSVHYGHYTALCRCQTG-WHVYNDSR 522
Query: 676 INKISEKQLLKEPNAYFLVY 695
++ +SE Q+ Y L Y
Sbjct: 523 VSPVSENQVASS-EGYVLFY 541
>CE23922 [O] KOG1864 Ubiquitin-specific protease
Length = 410
Score = 79.3 bits (194), Expect = 2e-14
Identities = 87/377 (23%), Positives = 149/377 (39%), Gaps = 100/377 (26%)
Query: 363 GLLNHGVTCYTNAAVQAMVHIPAIQHYLFQLLRGNFKDTVKSNCVSM-----LLAETTMR 417
GL+N G TCY N+ +QA+ + + N+K T+K + S LA+
Sbjct: 28 GLVNFGNTCYCNSVIQALFFCRPFREKVL-----NYKQTLKKSGASKDNLVTCLADLFHS 82
Query: 418 MWSSDSTKNTYINPDKLINALEDINCMMSAWNQEDSHE---YFMSLMSR--LQED----- 467
+ S T I P + I L+ N + + Q+D+HE Y ++ +S +QE
Sbjct: 83 IASQKRRVGT-IAPKRFITKLKKENELFDNYMQQDAHEFFNYLINTISETLIQEKIAERE 141
Query: 468 ------SVPKGHKM-------------------------------------TESIIYDVF 484
++ KG+ T + I+++F
Sbjct: 142 KASRHGTLKKGNVTVNLAPATAGLPRSDEKGTSERNGGITVEGNEFLNKSDTTTWIHEIF 201
Query: 485 GGLLQQSVKCSNCGEISTTEQPIYDLSLHLKGRKTTDQDQNSVGQDNSIDNSVDQQQSSK 544
G+L +C +C +S+ ++ DLS+ D +QN+
Sbjct: 202 QGILTNETRCLSCETVSSKDEDFLDLSI--------DVEQNT------------------ 235
Query: 545 RRFSIEKSIRDFFNPELIKRVDNKEGYTCEKCKKVTNALKSNKIIRAPETLVVHLKKFRF 604
SI +R F E + + Y CE C A K +I + P+ L +HLK+F+F
Sbjct: 236 ---SISHCLRVFSETETLC---GDQKYFCETCSSKQEAQKRMRIKKPPQLLALHLKRFKF 289
Query: 605 NG--TSSSKMKQAVSYPMFLDLTEYCHESISSLPVRYQLISVVVHEGRSLSSGHYIAHCK 662
+K+ V +P+ L L ++ Y L++ VVH G + + GHYI K
Sbjct: 290 VEPLNRHTKLSYRVVFPLELRLFNVSDDAEYG-DRMYDLVATVVHCGATPNRGHYITLVK 348
Query: 663 QPDGSWATYDDEYINKI 679
+ W +DD+ + K+
Sbjct: 349 S-NSFWLVFDDDIVEKL 364
>CE26210 [O] KOG1868 Ubiquitin C-terminal hydrolase
Length = 357
Score = 79.0 bits (193), Expect = 3e-14
Identities = 78/368 (21%), Positives = 145/368 (39%), Gaps = 69/368 (18%)
Query: 363 GLLNHGVTCYTNAAVQAMVHIPAIQHYLFQLL---RGNFKDTVKSN-CVSMLLAETTMRM 418
GL N G TC+ +A +Q + P + + + + N + + S +S A + +
Sbjct: 25 GLFNMGNTCFMSATLQCLFQTPGLAEVFTKKVFVSKVNTQSRLGSKGVISAGFASLSDMI 84
Query: 419 WSSDSTKNTYINPDKLINALED-INCMMSAWNQEDSHEYFMSLMSRLQEDS--------- 468
W+ T I P + + D + +S Q D+ E+ + L+ L ED+
Sbjct: 85 WNGTFTA---IRPSRFLQLFSDTVYQPLSDGRQHDASEFQIFLLDALHEDTNQAQRISFE 141
Query: 469 ----------------VPKGHKMTESIIYDVFGGLLQQSVKCSNCGEISTTEQPIYDLSL 512
+ K ++ + S + + G + ++C CG S T +
Sbjct: 142 QNYHGGAGIAKEAADFLKKHYQFSLSPVNRLLGSITVSEIRCLTCGASSATFE------- 194
Query: 513 HLKGRKTTDQDQNSVGQDNSIDNSVDQQQSSKRRFSIEKSIRDFFNPELIKRVDNKEGYT 572
+N+I + + S S++ +R F+ ++D +
Sbjct: 195 -----------------ENTI---ISVEIPSNSSCSLDMCLRSHFSQT---KLDGDSRWN 231
Query: 573 CEKCKKVTNALKSNKIIRAPETLVVHLKKFR-FNGTSSSKMKQAVSYPMFLDLTEYCHES 631
C KCK+ + +++K+ + P +++HLK+F FNG D+ Y HE
Sbjct: 232 CPKCKEPRASTRTSKLWQPPPVMIIHLKRFALFNGDFEKNTAAVTFETARFDVRPYLHEM 291
Query: 632 ISSLPVRYQLISVVVHEGRSLSSGHYIAHCKQ-PDGSWATYDDEYINKISEKQLLKEPN- 689
+ Y+L + +H GR L+SGHY A W +DD + ++ +P+
Sbjct: 292 APAEKPVYKLYAATLHNGR-LNSGHYTAVASHLRSDKWLRFDDSVVTPCENFKV--DPSL 348
Query: 690 AYFLVYTR 697
AY L Y R
Sbjct: 349 AYILFYKR 356
>Hs21361749 [O] KOG1867 Ubiquitin-specific protease
Length = 640
Score = 78.2 bits (191), Expect = 4e-14
Identities = 67/281 (23%), Positives = 124/281 (43%), Gaps = 55/281 (19%)
Query: 418 MWSSDSTKNTYINPDKLINALEDINCMMSAWNQEDSHEYFMSLMSRLQEDSVPKG----- 472
MWS K ++P +++++ + ++Q+D+ E+ L+ ++Q++ +G
Sbjct: 368 MWSG---KWALVSPFAMLHSVWSLIPAFRGYDQQDAQEFLCELLHKVQQELESEGTTRRI 424
Query: 473 ------HKMTESI---IYDVFGGLLQQSVKCSNCGEISTTEQPIYDLSLHLKGR-KTTDQ 522
K+T+ + + +F G L V C +C S T +P +DLSL R ++
Sbjct: 425 LIPFSQRKLTKQVLKVVNTIFHGQLLSQVTCISCNYKSNTIEPFWDLSLEFPERYHCIEK 484
Query: 523 DQNSVGQDNSIDNSVDQQQSSKRRFSIEKSIRDFFNPELIK-RVDNKEGYTCEKCKK--- 578
+ Q + + + + F E ++ R+ Y C++C
Sbjct: 485 GFVPLNQTECL---------------LTEMLAKFTETEALEGRI-----YACDQCNSKRR 524
Query: 579 --------VTNALKSNKIIRAPETLVVHLKKFRFNGTSS-SKMKQAVSYPMFLDLTEYC- 628
++ A K I R P+ L +HLK+FR++G + K+ V + L + YC
Sbjct: 525 KSNPKPLVLSEARKQLMIYRLPQVLRLHLKRFRWSGRNHREKIGVHVVFDQVLTMEPYCC 584
Query: 629 HESISSLPVR---YQLISVVVHEGRSLSSGHYIAHCKQPDG 666
+ +SSL Y L +VV+H G+ SGHY A+C +G
Sbjct: 585 RDMLSSLDKETFAYDLSAVVMHHGKGFGSGHYTAYCYNTEG 625
>Hs22067085 [O] KOG1871 Ubiquitin-specific protease
Length = 798
Score = 77.8 bits (190), Expect = 6e-14
Identities = 97/407 (23%), Positives = 165/407 (39%), Gaps = 82/407 (20%)
Query: 355 KLTQLKPRGLLNHGVTCYTNAAVQAMVHIPAIQHYLFQLLRGNFKDTVKSNCVSMLLAET 414
K L+PRGL+N G CY NA +QA+V P + H + + V+ C S + ++
Sbjct: 408 KPVSLQPRGLINKGNWCYINATLQALVACPPMYHLMKFI---PLYSKVQRPCTSTPMIDS 464
Query: 415 TMRMWSSDSTKNTYINP-----DKLINALE----------------DINCMMSAWNQEDS 453
+R+ + + P DK++ + + + + QED+
Sbjct: 465 FVRLMNEFTNMPVPPKPRQALGDKIVRDIRPGAAFEPTYIYRLLTVNKSSLSEKGRQEDA 524
Query: 454 HEYFMSLMSRLQEDSV-------PKGHKMTESIIYDVFGGLLQQSV---KCSNCGEISTT 503
EY +++ L E+ + P K+T S G SV + GE S
Sbjct: 525 EEYLGFILNGLHEEMLNLKKLLSPSNEKLTIS------NGPKNHSVNEEEQEEQGEGSED 578
Query: 504 EQPIYDLSLHLKGRKTTDQDQNSV-GQDNSIDNSVDQQQSSKRRFSIE------------ 550
E + D Q + G SV QQSSK +++
Sbjct: 579 EWEQVGPRNKTSVTRQADFVQTPITGIFGGHIRSVVYQQSSKESATLQPFFTLQLDIQSD 638
Query: 551 --KSIRDFFNPELIKRVDNKEGYTCEKCKKVTNALKSNKIIRAPETLVVHLKKFRFNGTS 608
++++D L+ R ++ +GYT K K+ + + + P LV+HLK+F + T
Sbjct: 639 KIRTVQDALE-SLVAR-ESVQGYTT-KTKQEVEISRRVTLEKLPPVLVLHLKRFVYEKTG 695
Query: 609 S-SKMKQAVSYPMFLDLTEY------------CHESISSLPVRYQLISVVVHEGRSLSSG 655
K+ + + YP+ L++++ CH + Y+L +VV H G S + G
Sbjct: 696 GCQKLIKNIEYPVDLEISKELLSPGVKNKNFKCHRT-------YRLFAVVYHHGNSATGG 748
Query: 656 HYIAHCKQPD-GSWATYDDEYINKISEKQLLK---EPNAYFLVYTRL 698
HY Q W DD+ + I++ Q++K E AY L Y R+
Sbjct: 749 HYTTDVFQIGLNGWLRIDDQTVKVINQYQVVKPTAERTAYLLYYRRV 795
>7303452 [O] KOG1864 Ubiquitin-specific protease
Length = 852
Score = 77.4 bits (189), Expect = 7e-14
Identities = 56/244 (22%), Positives = 108/244 (43%), Gaps = 29/244 (11%)
Query: 478 SIIYDVFGGLLQQSVKCSNCGEISTTEQPIYDLSLHLKGRKTTDQDQNSVGQDNSIDNSV 537
S I F G L + +C NCG S E +L L
Sbjct: 539 STIDKTFAGKLSTTYRCLNCGWESRNEDSFRELQLSFPD--------------------- 577
Query: 538 DQQQSSKRRFSIEKSIRDFFNPELIKRVDNKEGYTCEKCKKVTNALKSNKIIRAPETLVV 597
D++ +S++ I + +PE ++D Y C +CKK+ +A + + +AP+ L++
Sbjct: 578 DKEDCGATNYSVQDLIEYYCSPE---KLDGDNQYFCPQCKKLCDAERHIGVTQAPKNLIL 634
Query: 598 HLKKFRFNGT--SSSKMKQAVSYPMFLDLTEYCHESISSL-PVRYQLISVVVHEGRSLSS 654
LK+F+++ +K+ V + + + +S+ + V Y L + VVH G S+ S
Sbjct: 635 TLKQFKYDQKYHFRTKLMHKVFHDESVTVKMSAKDSLQEMSTVHYDLYAGVVHAGYSMDS 694
Query: 655 GHYIAHCKQPDGSWATYDDEYI--NKISEKQLLKEPNAYFLVYTRLTPKSVPLSSQSSNK 712
GHY +W ++D + +K E L PN ++++ ++ S +S +++
Sbjct: 695 GHYFTFAADQAKNWYKFNDNVVTHSKPEEMHNLTSPNTPYILFYKMCGHSNESNSVTASC 754
Query: 713 STDL 716
S+ +
Sbjct: 755 SSSM 758
>Hs4507853 [O] KOG1870 Ubiquitin C-terminal hydrolase
Length = 963
Score = 76.6 bits (187), Expect = 1e-13
Identities = 61/204 (29%), Positives = 100/204 (48%), Gaps = 11/204 (5%)
Query: 517 RKTTDQDQNSVGQDNSIDNSVDQQQSSKRRFSIEKSIRDFFNPELIKRVDNKEGYTCEKC 576
R+ +Q S + + + + Q+ K ++ I F E + D + C C
Sbjct: 747 RRLYYDEQESEAYEKHV-SMLQPQKKKKTTVALRDCIELFTTMETLGEHDP---WYCPNC 802
Query: 577 KKVTNALKSNKIIRAPETLVVHLKKFRFNGTSSSKMKQAVSYPM-FLDLTEY-CHESISS 634
KK A K + P+ LVVHLK+F +N K+ V +P+ L+++E+ C ++S+
Sbjct: 803 KKHQQATKKFDLWSLPKILVVHLKRFSYNRYWRDKLDTVVEFPIRGLNMSEFVC--NLSA 860
Query: 635 LPVRYQLISVVVHEGRSLSSGHYIAHCKQP-DGSWATYDDEYINKISEKQLLKEPNAYFL 693
P Y LI+V H G ++ GHY A+ K +G W +DD ++ SE Q++ + AY L
Sbjct: 861 RPYVYDLIAVSNHYG-AMGVGHYTAYAKNKLNGKWYYFDDSNVSLASEDQIVTKA-AYVL 918
Query: 694 VYTRLTPKSVPLSSQSSNKSTDLG 717
Y R + S SS+ S+D G
Sbjct: 919 FYQRRDDEFYKTPSLSSSGSSDGG 942
>7300926 [O] KOG1864 Ubiquitin-specific protease
Length = 424
Score = 76.3 bits (186), Expect = 2e-13
Identities = 56/203 (27%), Positives = 95/203 (46%), Gaps = 38/203 (18%)
Query: 480 IYDVFGGLLQQSVKCSNCGEISTTEQPIYDLSLHLKGRKTTDQDQNSVGQDNSIDNSVDQ 539
++++F G+L +C NC +S+ ++ +DL + D DQN+
Sbjct: 224 VHEIFQGILTSETRCLNCETVSSKDENFFDLQV--------DVDQNT------------- 262
Query: 540 QQSSKRRFSIEKSIRDFFNPELIKRVDNKEGYTCEKCKKVTNALKSNKIIRAPETLVVHL 599
SI +R F N E + DNK + C+ C A K ++ + P L +HL
Sbjct: 263 --------SITHCLRCFSNTETLCS-DNK--FKCDNCCSYQEAQKRMRVKKLPMILALHL 311
Query: 600 KKFRF--NGTSSSKMKQAVSYPMFLDLTEYCHESISSLPVR-YQLISVVVHEGRSLSSGH 656
K+F++ K+ V +P+ L L ++++ P R Y L +VV+H G + GH
Sbjct: 312 KRFKYMEQFNRHIKVSHRVVFPLELRLFNTSDDAVN--PDRLYDLTAVVIHCGSGPNRGH 369
Query: 657 YIAHCKQPDGSWATYDDEYINKI 679
YI+ K G W +DD+ ++KI
Sbjct: 370 YISIVKS-HGLWLLFDDDMVDKI 391
>7295436 [O] KOG4598 Putative ubiquitin-specific protease
Length = 1248
Score = 75.9 bits (185), Expect = 2e-13
Identities = 76/306 (24%), Positives = 127/306 (40%), Gaps = 60/306 (19%)
Query: 354 SKLTQLKPRG---LLNHGVTCYTNAAVQAMVHIPAIQHYLFQLLRGNFKDTVKSNCVSML 410
++ L PRG L+N +TCY N+ +QA+ P ++ L+ R F + ++ +
Sbjct: 77 ARQASLGPRGYVGLVNQAMTCYLNSLLQALFMTPEFRNALY---RWEFDNDNEAKNIPYQ 133
Query: 411 LAETTMRMWSSDSTKNTYINPDKLINALEDINCMMS-------AWNQEDSHEYFMSLMSR 463
L + + + +S A+E + S AW Q D E + R
Sbjct: 134 LQKLFLNLQTSPKA------------AVETTDLTRSFGWDSTEAWQQHDIQE-----LCR 176
Query: 464 LQEDSVPKGHKMTE--SIIYDVFGGLLQQSVKCSNCGEISTTEQPIYDLSLHLKGRKTTD 521
+ D++ K T+ ++I +++ G + VKC C T E D+ L ++
Sbjct: 177 VMFDALEHKFKNTKQANLISNLYEGKMNDYVKCLECNTEKTREDTFLDIPLPVR------ 230
Query: 522 QDQNSVGQDNSIDNSVDQQQSSKRRFSIEKSIRDFFNPELIKRVDNKEGYTCEKCKKVTN 581
SS SIE+++R F PE + D Y CEKCKK +
Sbjct: 231 -----------------PFGSSSAYGSIEEALRAFVQPETL---DGNNQYLCEKCKKKCD 270
Query: 582 ALKSNKIIRAPETLVVHLKKFRFNGTSSSKMK--QAVSYPMFLDLTEYCHESISSLPVRY 639
A K P L +HLK+F F+ + ++K V++P L+L + + S +S
Sbjct: 271 AHKGLHFKSFPYILTLHLKRFDFDYQTMHRIKLNDRVTFPQTLNLNTFINRSGNSGEQNS 330
Query: 640 QLISVV 645
QL V
Sbjct: 331 QLNGTV 336
>Hs22043041 [O] KOG1866 Ubiquitin carboxyl-terminal hydrolase
Length = 959
Score = 75.5 bits (184), Expect = 3e-13
Identities = 88/410 (21%), Positives = 149/410 (35%), Gaps = 101/410 (24%)
Query: 363 GLLNHGVTCYTNAAVQAMVHIPAIQHYLFQLLRGNFKDTVKSNCVSMLLAETTMRMWSSD 422
GL N G TCY NA Q + P + L + D N + +
Sbjct: 29 GLRNGGATCYMNAVFQQLYMQPGLPESLLSV------DDDTDNPDDSVFYQVQSLFGHLM 82
Query: 423 STKNTYINPDKLINALEDINCMMSAWNQEDSHEYFMSLMSRLQEDSVPKGHKMTESIIYD 482
+K Y P+ + N + Q+D++E+F SL+ ++ E G + I +
Sbjct: 83 ESKLQYYVPENFWKIFKMWNKELYVREQQDAYEFFTSLIDQMDEYLKKMGR---DQIFKN 139
Query: 483 VFGGLLQQSVKCSNCGEISTTEQPIYDLSLHLKGRKTTDQDQNSVGQDNSIDNSVDQQQS 542
F G+ C +C E+ L+L V S++ S+DQ
Sbjct: 140 TFQGIYSDQKICKDCPHRYEREEAFMALNL-------------GVTSCQSLEISLDQ--- 183
Query: 543 SKRRFSIEKSIRDFFNPELIKRVDNKEGYTCEKCKKVTNALKSNKIIRAPETLVVHLKKF 602
F E++ + Y CEKCK+ +K I P LV+HL +F
Sbjct: 184 -------------FVRGEVL---EGSNAYYCEKCKEKRITVKRTCIKSLPSVLVIHLMRF 227
Query: 603 RFNGTS--SSKMKQAVSYPMFLDLTEYCHESIS--------------------------- 633
F+ S S K + + +P L++ Y ++
Sbjct: 228 GFDWESGRSIKYDEQIRFPWMLNMEPYTVSGMARQDSSSEVGENGRSVDQGGGGSPRKKV 287
Query: 634 SLPVRYQLISVVVHEGRSLSSGHYIAHCKQ----PDGSWATYDDEYINK--ISEKQLLKE 687
+L Y+L+ V+VH G++ +GHY + K G W ++D I + ++++ L E
Sbjct: 288 ALTENYELVGVIVHSGQA-HAGHYYSFIKDRRGCGKGKWYKFNDTVIEEFDLNDETLEYE 346
Query: 688 P------------------------NAYFLVYTRLTPKSVPLSSQSSNKS 713
NAY L Y R++ ++ P+ + S S
Sbjct: 347 CFGGEYRPKVYDQTNPYTDVRRRYWNAYMLFYQRVSDQNSPVLPKKSRVS 396
>7292738 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase
Length = 1129
Score = 75.5 bits (184), Expect = 3e-13
Identities = 81/355 (22%), Positives = 152/355 (42%), Gaps = 69/355 (19%)
Query: 363 GLLNHGVTCYTNAAVQAMVHIPAIQHYLFQLLRGNFKDTVKSNCVSMLLAETTMRMWSSD 422
GL N G TCY N+ +Q + +++ ++++ D+ KS +S+ R++
Sbjct: 242 GLKNQGATCYMNSLLQTLYFTNSLRLSVYRIPT-EADDSSKSVGLSL------QRVFHEL 294
Query: 423 STKNTYINPDKLINAL--EDINCMMSAWNQEDSHEYFMSLMSRLQEDSVPKGHKMTESII 480
+ + KL + E ++ M Q D E+ L+ +L+ S KG + E I
Sbjct: 295 QFGDRPVGTKKLTKSFGWETLDSFM----QHDVQEFLRVLLDKLE--SKMKG-TILEGTI 347
Query: 481 YDVFGGLLQQSVKCSNCGEISTTEQPIYDLSLHLKGRKTTDQDQNSVGQDNSIDNSVDQQ 540
+F G + +KC N ST + YD+ L++K +K
Sbjct: 348 PGLFEGKMSSYIKCKNVDYNSTRYETFYDIQLNIKDKK---------------------- 385
Query: 541 QSSKRRFSIEKSIRDFFNPELIKRVDNKEGYTCEKCKKVTNALKSNKIIRAPETLVVHLK 600
+I +S +D+ PE ++ DNK ++ + + P L +HL
Sbjct: 386 -------NIYESFQDYVAPETLEG-DNKYDAGVHGLQEASKGVIFTSF---PPVLHLHLM 434
Query: 601 KFRFNGTSSSKMKQAVSYPMF--LDLTEYCHESISSLPVRYQLISVVVHEGRSLSSGHYI 658
+F+++ + S +K + + ++L Y ES ++L Y L +V+VH G + GHY+
Sbjct: 435 RFQYDPVTDSSIKYNDRFEFYEHINLDRYLAESENTL-ADYVLHAVLVHSGDN-HGGHYV 492
Query: 659 AHCK-QPDGSWATYDDEYINKISEKQLLKE---------------PNAYFLVYTR 697
+ DG W +DD+ ++ +++ +++ NAY LVY R
Sbjct: 493 VFINPKADGRWFKFDDDVVSSCRKQEAIEQNYGGMDDEISFHAKCSNAYMLVYIR 547
>Hs14149627 [O] KOG1870 Ubiquitin C-terminal hydrolase
Length = 952
Score = 75.1 bits (183), Expect = 4e-13
Identities = 60/202 (29%), Positives = 96/202 (46%), Gaps = 13/202 (6%)
Query: 523 DQNSVGQDNSIDNSVDQQQSSKRRFSIEKSIRDFFNPELIKRVDNKEGYTCEKCKKVTNA 582
D+N+ +D SV+ + K ++ I F E ++ ++ + C CK+ A
Sbjct: 734 DENAA-EDFEKHESVEYKPPKKPFVKLKDCIELFTTKE---KLGAEDPWYCPNCKEHQQA 789
Query: 583 LKSNKIIRAPETLVVHLKKFRFNGTSSSKMKQAVSYPM-FLDLTEYCHESISSLPVRYQL 641
K + P LVVHLK+F ++ K+ V +P+ LD++E+ ++ P RY L
Sbjct: 790 TKKLDLWSLPPVLVVHLKRFSYSRYMRDKLDTLVDFPINDLDMSEFLINP-NAGPCRYNL 848
Query: 642 ISVVVHEGRSLSSGHYIAHCK-QPDGSWATYDDEYINKISEKQLLKEPNAYFLVYTRLTP 700
I+V H G + GHY A K + DG W +DD ++ SE Q++ + AY L Y R
Sbjct: 849 IAVSNHYG-GMGGGHYTAFAKNKDDGKWYYFDDSSVSTASEDQIVSKA-AYVLFYQRQDT 906
Query: 701 KS----VPLSSQSSNKSTDLGI 718
S PL ++ S GI
Sbjct: 907 FSGTGFFPLDRETKGASAATGI 928
Score = 56.2 bits (134), Expect = 2e-07
Identities = 47/189 (24%), Positives = 76/189 (39%), Gaps = 39/189 (20%)
Query: 363 GLLNHGVTCYTNAAVQAMVHIPAIQHYLFQLLRGNFKDTVKSNC-------VSMLLAETT 415
GL N G TC+ N+A+Q + + P + Y L +++ + + ++ AE
Sbjct: 261 GLSNLGNTCFMNSAIQCLSNTPPLTEYF---LNDKYQEELNFDNPLGMRGEIAKSYAELI 317
Query: 416 MRMWSSDSTKNTYINPDKLINALEDINCMMSAWNQEDSHEYFMSLMSRLQED-------- 467
+MWS K +Y+ P + S + Q+D E L+ L ED
Sbjct: 318 KQMWSG---KFSYVTPRAFKTQVGRFAPQFSGYQQQDCQELLAFLLDGLHEDLNRIRKKP 374
Query: 468 -----------------SVPKGH-KMTESIIYDVFGGLLQQSVKCSNCGEISTTEQPIYD 509
+ H K +SII D+F GL + ++ C C +IS T P
Sbjct: 375 YIQLKDADGRPDKVVAEEAWENHLKRNDSIIVDIFHGLFKSTLVCPECAKISVTFDPFCY 434
Query: 510 LSLHLKGRK 518
L+L L +K
Sbjct: 435 LTLPLPMKK 443
>Hs8394519 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase
Length = 372
Score = 73.2 bits (178), Expect = 1e-12
Identities = 77/352 (21%), Positives = 145/352 (40%), Gaps = 53/352 (15%)
Query: 363 GLLNHGVTCYTNAAVQAMVHIPAIQHYLFQLLRGNFKDTVKSNCVSMLLAETTMRMWSSD 422
GL N G TC N+ +Q V L ++ D + + +L + +
Sbjct: 56 GLHNIGQTCCLNSLIQVFVMNVDFTRILKRITVPRGADEQRRSVPFQML----LLLEKMQ 111
Query: 423 STKNTYINPDKLINALEDINCMMSAWNQEDSHEYFMSLMSRLQEDSVPKGHKMTESIIYD 482
++ + P +L L+ C + + Q D+ + ++ L + L +D + H + +
Sbjct: 112 DSRQKAVRPLELAYCLQ--KCNVPLFVQHDAAQLYLKLWN-LIKDQITDVHLVER--LQA 166
Query: 483 VFGGLLQQSVKCSNCGEISTTEQPIYDLSLHLKGRKTTDQDQNSVGQDNSIDNSVDQQQS 542
++ ++ S+ C +C S+ + L L L D D
Sbjct: 167 LYTIRVKDSLICVDCAMESSRNSSMLTLPLSL-----FDVD------------------- 202
Query: 543 SKRRFSIEKSIRDFFNPELIKRVDNKEGYTCEKCKKVTNALKSNKIIRAPETLVVHLKKF 602
SK ++E ++ FF P + + +K CE C K T + K+ P+TL +HL +F
Sbjct: 203 SKPLKTLEDALHCFFQP---RELSSKSKCFCENCGKKTRGKQVLKLTHLPQTLTIHLMRF 259
Query: 603 RFNGTSSSKMKQAVSYPMFLDLTEYCHESISSLPV------RYQLISVVVHEGRSLSSGH 656
+ + K+ ++ +P LD ++ S +Y+L +V+ H G + SGH
Sbjct: 260 SIRNSQTRKICHSLYFPQSLDFSQILPMKRESCDAEEQSGGQYELFAVIAHVGMA-DSGH 318
Query: 657 YIAHCKQP-DGSWATYDDEYINKISEKQL---LKEPN------AYFLVYTRL 698
Y + + DG W+ ++D I +S + + PN AY LVY ++
Sbjct: 319 YCVYIRNAVDGKWSCFNDSNICLVSWEDIQCTYGNPNYHWQETAYLLVYMKM 370
>Hs14776897 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase
Length = 372
Score = 72.0 bits (175), Expect = 3e-12
Identities = 77/352 (21%), Positives = 144/352 (40%), Gaps = 53/352 (15%)
Query: 363 GLLNHGVTCYTNAAVQAMVHIPAIQHYLFQLLRGNFKDTVKSNCVSMLLAETTMRMWSSD 422
GL N G TC N+ +Q V L ++ D + + +L + +
Sbjct: 56 GLHNIGQTCCLNSLIQVFVMNVDFTRILKRITVPRGADEQRRSVPFQML----LLLEKMQ 111
Query: 423 STKNTYINPDKLINALEDINCMMSAWNQEDSHEYFMSLMSRLQEDSVPKGHKMTESIIYD 482
++ + P +L L+ C + + Q D+ + ++ L + L +D + H + +
Sbjct: 112 DSRQKAVRPLELAYCLQ--KCNVPLFVQHDAAQLYLKLWN-LIKDQITDVHLVER--LQA 166
Query: 483 VFGGLLQQSVKCSNCGEISTTEQPIYDLSLHLKGRKTTDQDQNSVGQDNSIDNSVDQQQS 542
++ ++ S+ C +C S+ + L L L D D
Sbjct: 167 LYTIRVKDSLICVDCAMESSRNSSMLTLPLSL-----FDVD------------------- 202
Query: 543 SKRRFSIEKSIRDFFNPELIKRVDNKEGYTCEKCKKVTNALKSNKIIRAPETLVVHLKKF 602
SK ++E ++ FF P + + +K CE C K T + K+ P+TL +HL +F
Sbjct: 203 SKPLKTLEDALHCFFQP---RELSSKSKCFCENCGKKTRGKQVLKLTHLPQTLTIHLMRF 259
Query: 603 RFNGTSSSKMKQAVSYPMFLDLTEYCHESISSLPV------RYQLISVVVHEGRSLSSGH 656
+ + K+ ++ +P LD ++ S +Y+L +V+ H G + SGH
Sbjct: 260 SIRNSQTRKICHSLYFPQSLDFSQILPMKRESCDAEEQSGGQYELFAVIAHVGMA-DSGH 318
Query: 657 YIAHCKQP-DGSWATYDDEYINKISEKQL---LKEPN------AYFLVYTRL 698
Y + + DG W ++D I +S + + PN AY LVY ++
Sbjct: 319 YCVYIRNAVDGKWFCFNDSNICLVSWEDIQCTYGNPNYHWQETAYLLVYMKM 370
>CE23923 [O] KOG1864 Ubiquitin-specific protease
Length = 398
Score = 71.2 bits (173), Expect = 5e-12
Identities = 53/206 (25%), Positives = 91/206 (43%), Gaps = 36/206 (17%)
Query: 476 TESIIYDVFGGLLQQSVKCSNCGEISTTEQPIYDLSLHLKGRKTTDQDQNSVGQDNSIDN 535
T + I+++F G+L +C +C +S+ ++ DLS+ D +QN+
Sbjct: 181 TTTWIHEIFQGILTNETRCLSCETVSSKDEDFLDLSI--------DVEQNT--------- 223
Query: 536 SVDQQQSSKRRFSIEKSIRDFFNPELIKRVDNKEGYTCEKCKKVTNALKSNKIIRAPETL 595
SI +R F E + + Y CE C A K +I + P+ L
Sbjct: 224 ------------SISHCLRVFSETETLC---GDQKYFCETCSSKQEAQKRMRIKKPPQLL 268
Query: 596 VVHLKKFRFNG--TSSSKMKQAVSYPMFLDLTEYCHESISSLPVRYQLISVVVHEGRSLS 653
+HLK+F+F +K+ V +P+ L L ++ Y L++ VVH G + +
Sbjct: 269 ALHLKRFKFVEPLNRHTKLSYRVVFPLELRLFNVSDDAEYG-DRMYDLVATVVHCGATPN 327
Query: 654 SGHYIAHCKQPDGSWATYDDEYINKI 679
GHYI K + W +DD+ + K+
Sbjct: 328 RGHYITLVKS-NSFWLVFDDDIVEKL 352
>Hs22045513 [O] KOG1868 Ubiquitin C-terminal hydrolase
Length = 907
Score = 70.9 bits (172), Expect = 7e-12
Identities = 83/314 (26%), Positives = 132/314 (41%), Gaps = 63/314 (20%)
Query: 341 GSNKPQRIVKNWGSKLTQLKPRGLLNHGVTCYTNAAVQAMVHIPAIQHYLFQLLRGNFKD 400
G NKP+ + S Q + +G N G TCY NA +Q++ + + + L L +G
Sbjct: 252 GWNKPRVPL----SSHQQQQLQGFSNLGNTCYMNAILQSLFSLQSFANDL--LKQGIPWK 305
Query: 401 TVKSNCVSMLLAETTMRMWSSDS-TKNTYINPDKLINALEDINCMMSAWNQEDSHEYFMS 459
+ N + A ++ +S TK + K+ NA+ S + Q D+HE+
Sbjct: 306 KIPLNALIRRFAHLLVKKDICNSETKKDLLK--KVKNAISATAERFSGYMQNDAHEFLSQ 363
Query: 460 LMSRLQEDSVPKGHKM-----------------TESIIYDVFGGL---LQQSVKCSNCGE 499
+ +L+ED + K +K T + V L +Q S+ C CGE
Sbjct: 364 CLDQLKED-MEKLNKTWKTEPVSGEENSPDISATRAYTCPVITNLEFEVQHSIICKACGE 422
Query: 500 ISTTEQPIYDLSLHLKGRKTTDQDQNSVGQDNSIDNSVDQQQSSKRRFSIEKSIRDFFNP 559
I + DLS+ L RK + SI+ S+ FF
Sbjct: 423 IIPKREQFNDLSIDLPRRKKPLPPR-----------------------SIQDSLDLFFRA 459
Query: 560 ELIKRVDNKEGYTCEKCKKVTNALKSNKIIRAPETLVVHLKKFRFNGTSS--SKMKQAVS 617
E ++ Y+CEKC AL +K R P L++HLK++ FN S +K+ Q V
Sbjct: 460 EELE-------YSCEKCGGKC-ALVRHKFNRLPRVLILHLKRYSFNVALSLNNKIGQQVI 511
Query: 618 YPMFLDLTEYCHES 631
P +L L+ +C E+
Sbjct: 512 IPRYLTLSSHCTEN 525
>Hs4507857 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase
Length = 1102
Score = 69.7 bits (169), Expect = 2e-11
Identities = 78/355 (21%), Positives = 142/355 (39%), Gaps = 69/355 (19%)
Query: 363 GLLNHGVTCYTNAAVQAMVHIPAIQHYLFQLLRGNFKDTVKSNCVSMLLAETTMRMWSSD 422
GL N G TCY N+ +Q + ++ ++ ++ D+ KS V + L + SD
Sbjct: 215 GLKNQGATCYMNSLLQTLFFTNQLRKAVY-MMPTEGDDSSKS--VPLALQRVFYELQHSD 271
Query: 423 STKNTYINPDKLINALEDINCMMSAWNQEDSH-EYFMSLMSRLQEDSVPKGHKMT--ESI 479
T KL + W DS ++ + + R+ D+V K T E
Sbjct: 272 KPVGT----KKLTKSF--------GWETLDSFMQHDVQELCRVLLDNVENKMKGTCVEGT 319
Query: 480 IYDVFGGLLQQSVKCSNCGEISTTEQPIYDLSLHLKGRKTTDQDQNSVGQDNSIDNSVDQ 539
I +F G + ++C S + YD+ L +KG+K
Sbjct: 320 IPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKK--------------------- 358
Query: 540 QQSSKRRFSIEKSIRDFFNPELIKRVDNKEGYTCEKCKKVTNALKSNKIIRAPETLVVHL 599
+I +S D+ ++++D Y + + A K K + P L + L
Sbjct: 359 --------NIFESFVDYV---AVEQLDGDNKYDAGE-HGLQEAEKGVKFLTLPPVLHLQL 406
Query: 600 KKFRFNGTSSSKMK--QAVSYPMFLDLTEYCHESISSLPVRYQLISVVVHEGRSLSSGHY 657
+F ++ + +K +P L L E+ ++ P Y L +V+VH G + GHY
Sbjct: 407 MRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQKTDPKDPANYILHAVLVHSGDN-HGGHY 465
Query: 658 IAHCK-QPDGSWATYDDEYINKISEKQLLKE--------------PNAYFLVYTR 697
+ + + DG W +DD+ +++ ++++ ++ NAY LVY R
Sbjct: 466 VVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHNYGGHDDDLSVRHCTNAYMLVYIR 520
>Hs22068900 [O] KOG1870 Ubiquitin C-terminal hydrolase
Length = 909
Score = 69.7 bits (169), Expect = 2e-11
Identities = 49/172 (28%), Positives = 83/172 (47%), Gaps = 27/172 (15%)
Query: 563 KRVDNKEGYTCEKCKKVTNALKSNKIIRAPETLVVHLKKFRFNGTSSSKMKQAVSYPMF- 621
+R+ + + C CK++ + + P+ L++HLK+FR G K++ V +P+
Sbjct: 166 ERLAPDDAWRCPHCKQLQQGSITLSLWTLPDVLIIHLKRFRQEGDRRMKLQNMVKFPLTG 225
Query: 622 LDLTEYC---HESISSLPVR------------------YQLISVVVHEGRSLSSGHYIAH 660
LD+T + +S SLP Y L +V H G ++ GHY A+
Sbjct: 226 LDMTPHVVKRSQSSWSLPSHWSPWRRPYGLGRDPEDYIYDLYAVCNHHG-TMQGGHYTAY 284
Query: 661 CKQP-DGSWATYDDEYINKISEKQLLKEPNAYFLVYTRLTPKSVPLSSQSSN 711
CK DG W +DD + ++SE ++ + AY L Y R T ++P S +S+
Sbjct: 285 CKNSVDGLWYCFDDSDVQQLSEDEVCTQ-TAYILFYQRRT--AIPSWSANSS 333
>At4g10590 [O] KOG1870 Ubiquitin C-terminal hydrolase
Length = 937
Score = 69.7 bits (169), Expect = 2e-11
Identities = 45/146 (30%), Positives = 79/146 (53%), Gaps = 8/146 (5%)
Query: 573 CEKCKKVTNALKSNKIIRAPETLVVHLKKFRFNGTSSSKMKQAVSYPMF-LDLTEYCHES 631
C CK+ A K + + P+ LV HLK+F ++ +K+ V++P+ LDL++Y ++
Sbjct: 797 CPSCKEHRQANKKLDLWKLPDILVFHLKRFTYSRYLKNKIDTFVNFPVHDLDLSKYV-KN 855
Query: 632 ISSLPVRYQLISVVVHEGRSLSSGHYIAHCKQ-PDGSWATYDDEYINKISEKQLLKEPNA 690
+ Y+L +V H G L GHY A+ K D W +DD +++ ++E + +K A
Sbjct: 856 KNDQSYLYELYAVSNHYG-GLGGGHYTAYAKLIDDNEWYHFDDSHVSSVNESE-IKNSAA 913
Query: 691 YFLVYTRLTPKSVPLSSQSSNKSTDL 716
Y L Y R+ ++ +Q+ STD+
Sbjct: 914 YVLFYRRVRSET---ETQTVEMSTDM 936
Score = 57.4 bits (137), Expect = 8e-08
Identities = 52/186 (27%), Positives = 73/186 (38%), Gaps = 32/186 (17%)
Query: 363 GLLNHGVTCYTNAAVQAMVHIPAIQHYLFQLLRGNF-KDTVKSNCVSMLLA--ETTMRMW 419
GL N G TC+ N+A+Q + H P I Y Q + +D C + +A + ++W
Sbjct: 331 GLSNLGNTCFMNSALQCLAHTPPIVEYFLQDYSDDINRDNPLGMCGELAIAFGDLLKKLW 390
Query: 420 SSDSTKNTYINPDKLINALEDINCMMSAWNQEDSHEYFMSLMSRLQED------------ 467
SS + P L S +NQ DS E L+ L ED
Sbjct: 391 SSGRNS---VAPRAFKTKLARFAPQFSGYNQHDSQELLAFLLDGLHEDLNKVKRKPYIEL 447
Query: 468 ----SVPKG---------HKM-TESIIYDVFGGLLQQSVKCSNCGEISTTEQPIYDLSLH 513
S P HK +S+I DV G + ++ C CG+IS T P LS+
Sbjct: 448 KDSDSRPDDEVAEELWNYHKARNDSVIVDVCQGQYKSTLVCPACGKISITFDPFMYLSVP 507
Query: 514 LKGRKT 519
L T
Sbjct: 508 LPSTLT 513
>At4g10570 [O] KOG1870 Ubiquitin C-terminal hydrolase
Length = 928
Score = 69.7 bits (169), Expect = 2e-11
Identities = 44/146 (30%), Positives = 80/146 (54%), Gaps = 8/146 (5%)
Query: 573 CEKCKKVTNALKSNKIIRAPETLVVHLKKFRFNGTSSSKMKQAVSYPMF-LDLTEYCHES 631
C CK+ A K + + P+ LV HLK+F ++ +K+ V++P+ LDL++Y ++
Sbjct: 776 CPSCKEHRQANKKLDLWKLPDILVFHLKRFTYSRYLKNKIDTFVNFPVHDLDLSKYV-KN 834
Query: 632 ISSLPVRYQLISVVVHEGRSLSSGHYIAHCKQ-PDGSWATYDDEYINKISEKQLLKEPNA 690
+ Y+L +V H G L GHY A+ K D W +DD +++ ++E + ++ A
Sbjct: 835 KNGQSYLYELYAVSNHYG-GLGGGHYTAYAKLIDDNKWYHFDDSHVSSVNESE-IRNSAA 892
Query: 691 YFLVYTRLTPKSVPLSSQSSNKSTDL 716
Y L Y R+ ++ +Q++ STD+
Sbjct: 893 YVLFYRRVRSET---ETQTAEMSTDM 915
>SPBC18H10.08c [O] KOG1868 Ubiquitin C-terminal hydrolase
Length = 438
Score = 69.3 bits (168), Expect = 2e-11
Identities = 83/387 (21%), Positives = 147/387 (37%), Gaps = 88/387 (22%)
Query: 360 KPRGLLNHGVTCYTNAAVQAMVHIPAIQHYLFQLLRG-------NFKDTV----KSNCVS 408
+P GL N G TCY N +Q + A + +L+G N K+ + K
Sbjct: 70 QPIGLTNLGNTCYMNCVLQCLF---ACKDLTIPMLQGRGLLQNINTKNPLGTGGKITSAF 126
Query: 409 MLLAETTMRMWSSDSTKNTYINPDKLINALEDINCMMSAWNQEDSHEYFMSLMSRLQED- 467
L ++ + S I+P + ++ +N S Q D+ E+ + +L ED
Sbjct: 127 FSLLQSVLLNHGQRS-----ISPRNFLEIVQSLNRDFSIDGQCDAQEFLNFFLDKLHEDL 181
Query: 468 ---------------------SVPKGH----------KMTESIIYDVFGGLLQQSVKCSN 496
+P H + +SI+ + F G L +C
Sbjct: 182 NSNASRSPIAPLTEDQLSAREELPLSHFSHIEWNLHLRSNKSIVVNNFVGQLCSRTQCMT 241
Query: 497 CGEISTTEQPIYDLSLHLKGRKTTDQDQNSVGQDNSIDNSVDQQQSSKRRFSIEKSIRDF 556
CG STT P L++ + D + V S+++ + F
Sbjct: 242 CGRTSTTFAPFTSLAIPI-------DDVSHV-------------------VSLQECLLKF 275
Query: 557 FNPELIKRVDNKEGYTCEKCKKVTNALKSNKIIRAPETLVVHLKKFRFNGTSSSKMKQ-- 614
PEL++ +G+ C CK +A K I + PE L++ +++F+ + K+
Sbjct: 276 SAPELLQ---GHDGWHCPVCKVQRSAKKVIMISKLPEYLIIQIQRFKISVMGRKKIDTPL 332
Query: 615 --AVSYPMFLDLTEYCHESISSLPVRYQLISVVVHEGRSLSSGHYIAHCKQPDGSWATYD 672
++ P + + I +P Y L + + H G+ L +GHYI+ + W D
Sbjct: 333 GLSLQIPSKMLVPPSFQSGIGYIPSNYNLFAFICHYGQ-LENGHYISDVLF-NNEWCHID 390
Query: 673 DEYINKISEKQLLKE--PNAYFLVYTR 697
D + + L+E ++Y L Y R
Sbjct: 391 DSIVRTVGGITDLREDFSSSYILFYKR 417
>YJL197w [O] KOG1870 Ubiquitin C-terminal hydrolase
Length = 1254
Score = 68.9 bits (167), Expect = 3e-11
Identities = 44/163 (26%), Positives = 81/163 (48%), Gaps = 7/163 (4%)
Query: 537 VDQQQSSKRRFSIEKSIRDFFNPELIKRVDNKEGYTCEKCKKVTNALKSNKIIRAPETLV 596
+++ + +R +++ ++ F PE++ D+ + C CK+ A K ++ P+ L+
Sbjct: 952 LERSNAKERTITLDDCLQLFSKPEILGLTDS---WYCPTCKEHRQATKQIQLWNTPDILL 1008
Query: 597 VHLKKFRFNGTSSSKMKQAVSYPMF-LDLTEYCHESISSLPVRYQLISVVVHEGRSLSSG 655
+HLK+F + S K+ V++P+ LDL+ Y + Y L +V H G L G
Sbjct: 1009 IHLKRFESQRSFSDKIDATVNFPITDLDLSRYVVYKDDPRGLIYDLYAVDNHYG-GLGGG 1067
Query: 656 HYIAHCKQ-PDGSWATYDDEYINKISEKQLLKEPNAYFLVYTR 697
HY A+ K D W +DD + + + + + +AY L Y R
Sbjct: 1068 HYTAYVKNFADNKWYYFDDSRVTETAPENSI-AGSAYLLFYIR 1109
Score = 61.2 bits (147), Expect = 6e-09
Identities = 47/195 (24%), Positives = 81/195 (41%), Gaps = 46/195 (23%)
Query: 363 GLLNHGVTCYTNAAVQAMVHIPAIQHYLFQLLRGNFKDTVKS-------NCVSMLLAETT 415
GL+N G TCY N+A+Q +VHIP ++ Y L ++D + V+ ++
Sbjct: 365 GLVNLGNTCYMNSALQCLVHIPQLRDY---FLYDGYEDEINEENPLGYHGYVARAFSDLV 421
Query: 416 MRMWS---SDSTKNTYINPDKLINALEDINCMMSAWNQEDSHEYFMSLMSRLQED----- 467
+++ S +N P + + N M S + Q+DS E+ L+ L ED
Sbjct: 422 QKLFQNRMSIMQRNAAFPPSMFKSTIGHFNSMFSGYMQQDSQEFLAFLLDSLHEDLNRII 481
Query: 468 --------SVPKGHKMTE--------------------SIIYDVFGGLLQQSVKCSNCGE 499
S+ G + + S+I D+F G+ + ++ C C
Sbjct: 482 KKEYTEKPSLSPGDDVNDWNVVKKLADDTWEMHLKRNCSVITDLFVGMYKSTLYCPECQN 541
Query: 500 ISTTEQPIYDLSLHL 514
+S T P D++L L
Sbjct: 542 VSITFDPYNDVTLPL 556
>SPBP8B7.21 [O] KOG1871 Ubiquitin-specific protease
Length = 512
Score = 68.6 bits (166), Expect = 3e-11
Identities = 95/428 (22%), Positives = 168/428 (39%), Gaps = 75/428 (17%)
Query: 326 DKSSFYQFNESINDHGSNKPQRIVKNWGSKLTQ---LKPRGLLNHGVTCYTNAAVQAMVH 382
D+S FN S+ + +++ + L ++PRG +N G C+ N+ +QA+++
Sbjct: 102 DRSEKKSFNSSLGE--------LIETYSPSLDAPRPIQPRGFINTGNICFMNSILQALMY 153
Query: 383 IPAIQHYLFQLLRG---NFKDTVKSNCVSMLLAETTMRMWSSD-STKNTYINPDKLINAL 438
+ L Q+ R NF+ T S+ + R +S + I P+ + +A
Sbjct: 154 CVPFYNLLKQINRMVPYNFERTTPL-IESLTMLSRDFREYSEKFDLQGDSILPEVVYSAT 212
Query: 439 EDINC--MMSAWNQEDSHEYFMSLMSRLQEDSV-----------PKGHKMTESIIYDVFG 485
+ M+ QED+ E+ + L E+ V + K I +
Sbjct: 213 KGNPRFEMLQTGEQEDAEEFLNLFLDELHEEFVRERRHYLLKNDERNPKSDIKISNGIKS 272
Query: 486 GLL----QQSVKCSNCGEISTTEQPIYDLSL-------------HLKGRKTTDQDQNSVG 528
GL Q SV+ S E+ ++P+ S L+ ++SV
Sbjct: 273 GLDSFDDQSSVEASGWTEVGKNKKPVIARSATVERSPISQIFGGQLRSTLRVPSARDSVL 332
Query: 529 QDNSIDNSVDQQQSSKRRFSIEKSIRDFFNPELIKRVDNKEGYTCEKCKKVTNALKSNKI 588
+ +D Q S+ ++ PE++ + +G A K I
Sbjct: 333 LEPFQPLQLDIQAEDIH--SVIDALEHMTAPEILPEWHSSKGNV--------TATKQMYI 382
Query: 589 IRAPETLVVHLKKFRFNGTSSS-KMKQAVSYPMFLDLTE--YCHESISSLPVRYQLISVV 645
P L++HLK+F + + + K + ++YP L + + + S+ Y L +VV
Sbjct: 383 ESLPPVLILHLKRFFYEASGGTQKNYKPIAYPARLSIPQNVFSPSVRGSIHPEYDLNAVV 442
Query: 646 VHEGRSLSSGHYIAHCKQPDGS-WATYDDEYINK-----ISEKQLLKEPN---------- 689
H G S S GHY +Q D S W DD +I++ + +L +P+
Sbjct: 443 YHHGTSASGGHYTVDVQQLDKSGWFRIDDTHIHRVPIHDVENSELSADPSLSKLGHGDRV 502
Query: 690 AYFLVYTR 697
AY L YTR
Sbjct: 503 AYLLFYTR 510
>CE15615 [O] KOG1872 Ubiquitin-specific protease
Length = 489
Score = 68.2 bits (165), Expect = 5e-11
Identities = 85/412 (20%), Positives = 161/412 (38%), Gaps = 104/412 (25%)
Query: 355 KLTQLKPRGLLNHGVTCYTNAAVQAMVHIPAIQHYLFQLLRGNFKDTVKSNCVSMLLAET 414
+++ L P GL N G TCY N+ VQ + + + + +R ++ C ++
Sbjct: 95 EISALYPCGLANLGNTCYFNSCVQMLKEVNELVLKPAEEMR--IREHNDRLCHNLATLFN 152
Query: 415 TMRMWSSD-STKNTYINPDKLINALEDINCMMSAWNQEDSHEYFMSLMSRLQEDSVPKGH 473
++R +K I P I L D + Q+D++E +S+MS +V + +
Sbjct: 153 SLRDKDRALRSKGEPIKPFAAILTLSDSFPQFEKFKQQDANECLVSIMS-----NVTRIY 207
Query: 474 KMTESIIYDVFGGLLQQSVKCSNCGEISTTEQPIYDLSLHLKGRKTTDQDQNSVGQDNSI 533
++ I +F + ++KC E+S + V ++N +
Sbjct: 208 GLSGWNIESLFRIQTETTMKCLESDEVS----------------------EKKVERNNQL 245
Query: 534 DNSVDQQQSSKRRFSIEKSIRDFFNPELIKRVDNKEGYTCEKCKKVTNALKSNKIIRAPE 593
V+Q RF ++ I+ F E+ + E+ + K+ +I R P+
Sbjct: 246 TCYVNQDV----RF-LQTGIKAGFEEEMTRN--------SEELNRDAKWQKNTQISRLPK 292
Query: 594 TLVVHLKKFRFNGTS--SSKMKQAVSYPMFLDLTEYCHESIS------------------ 633
L V++ +F + ++ ++K+ ++V +PM LD + C + +
Sbjct: 293 YLTVNINRFFYKESTKTNAKILKSVQFPMQLDTYDLCSQELKDKLVARRADIKLEEDAKL 352
Query: 634 ----------------------SLPVR------------YQLISVVVHEGRSLSSGHYIA 659
+LP Y L ++ H+GRS GHY+A
Sbjct: 353 ERELRKKVLDKEQGDKIFDDGVALPTAFEDDAGSNNSGFYDLKGIITHKGRSSQDGHYVA 412
Query: 660 HCK-QPDGSWATYDDEYINKISEKQLLKEP------NAYFLVYTRLTPKSVP 704
+ DG W +DDE++ + E+ +LK +AY L+Y K P
Sbjct: 413 WMRSSEDGKWRLFDDEHVTVVDEEAILKTSGGGDWHSAYVLLYEARVIKQFP 464
>7291841 [O] KOG1870 Ubiquitin C-terminal hydrolase
Length = 1096
Score = 68.2 bits (165), Expect = 5e-11
Identities = 58/238 (24%), Positives = 95/238 (39%), Gaps = 53/238 (22%)
Query: 524 QNSVGQDNSIDNSVDQQQSSKRRFSIEKSIRDFFNPELIKRVDNKEGYTCEKCKKVTNAL 583
+ +V + S+ + S ++E+ + + E + D + C C++ +
Sbjct: 503 EEAVVEHESVARLSASKPSDTAALTLEQCLEHYTKAETLSAED---AWRCPHCQQYLPVV 559
Query: 584 KSNKIIRAPETLVVHLKKFRFN---GTSSSKMKQAVSYP-----MFLDLTEYCHESISSL 635
K+ + P+ LVVH K+FR + G ++K+ V +P M L HES SS
Sbjct: 560 KTLGLWSLPDILVVHFKRFRQHQSKGPQAAKLTTMVKFPLTAFDMSPHLARGVHESASSS 619
Query: 636 --------------------------------------PVRYQLISVVVHEGRSLSSGHY 657
RY L +V H+G +L +GHY
Sbjct: 620 LGMGTGIGLGLGLGSNPWKKARSVDSRSSTLNSRCDAKDTRYDLYAVCYHQGDTLETGHY 679
Query: 658 IAHCKQP-DGSWATYDDEYINKISE---KQLLKEPNAYFLVYTRLTPKSVPLSSQSSN 711
A CK P D W +DD+ ++K+ E +Q + AY L Y R + + S SSN
Sbjct: 680 TAACKNPYDRQWYKFDDQRVSKVPEDDIEQDIINNEAYMLFYQRRSVDAGECSGSSSN 737
>Hs22044589 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 449
Score = 67.8 bits (164), Expect = 6e-11
Identities = 66/300 (22%), Positives = 121/300 (40%), Gaps = 49/300 (16%)
Query: 363 GLLNHGVTCYTNAAVQAMVHIPAIQHYLFQLLRGNFKDTVKSNCVSMLLAETTMRMWSSD 422
GL N G TCY NA++Q + + + +Y+ K + + A T +
Sbjct: 198 GLQNMGNTCYVNASLQCLTYTTPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALH--- 254
Query: 423 STKNTYINPDKLINALEDINCMMSAWNQEDSHEYFMSLMSRLQEDSVPKGHKMTESIIYD 482
NP +I + + QED+HE+ M + +++ ++P +
Sbjct: 255 -------NPGHVIQPSQALAAGFHRGKQEDAHEFLMFTVDAMKKHALPGTSRWI------ 301
Query: 483 VFGGLLQQSVKCSNCGEISTTEQPIYDLSLHLKGRKTTDQDQNSVGQDNSIDNSVDQQQS 542
I+ P L G D S D +D ++D Q +
Sbjct: 302 -----------------ITLRTPPSSTKYLEATG------DLKSNTFDPYLDIALDIQAA 338
Query: 543 SKRRFSIEKSIRDFFNPELIKRVDNKEGYTCEKCKKVTNALKSNKIIRAPETLVVHLKKF 602
S+++++ PE ++ + Y C C + A K+ + + + L++ LK
Sbjct: 339 Q----SVQQALEQLVKPE---ELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLK-- 389
Query: 603 RFNGTSSSKMKQAVSYPMFLDLTEYCHESISSLPVRYQLISVVVHEGRSLSSGHYIAHCK 662
RF+ + +K+ + V YP LD+ Y + + P+ Y L +V+VH G S +GHY + K
Sbjct: 390 RFSDVTGNKIAKNVQYPECLDMQPYMSHTNTG-PLVYVLYAVLVHAGWSCYNGHYFFYVK 448
>Hs20472401 [O] KOG1870 Ubiquitin C-terminal hydrolase
Length = 1320
Score = 67.8 bits (164), Expect = 6e-11
Identities = 52/182 (28%), Positives = 83/182 (45%), Gaps = 16/182 (8%)
Query: 547 FSIEKSIRDFFNPELIKRVDNKEGYTCEKCKKVTNALKSNKIIRAPETLVVHLKKFRFNG 606
F++++ + F PE++ +E + C +CK+ A K + R P L+V LK+F F
Sbjct: 1060 FTLDQCLNLFTRPEVLAP---EEAWYCPQCKQHREASKQLLLWRLPNVLIVQLKRFSFRS 1116
Query: 607 -TSSSKMKQAVSYPM-FLDLTEYCHESISSLPVRYQLISVVVHEGRSLSSGHYIAHCKQP 664
K+ V +P+ LDL+++C Y L +V+ H G + GHY A + P
Sbjct: 1117 FIWRDKINDLVEFPVRNLDLSKFCIGQKEEQLPSYDLYAVINHYG-GMIGGHYTACARLP 1175
Query: 665 --------DGSWATYDDEYINKISEKQLLKEPNAYFLVYTRL-TPKSVPLSSQSSNKSTD 715
D W +DD + + E Q++ AY L Y R +P P + S D
Sbjct: 1176 NDRSSQRSDVGWRLFDDSTVTTVDESQVVTR-YAYVLFYRRRNSPVERPPRAGHSEHHPD 1234
Query: 716 LG 717
LG
Sbjct: 1235 LG 1236
>Hs4759290 [O] KOG1870 Ubiquitin C-terminal hydrolase
Length = 690
Score = 67.0 bits (162), Expect = 1e-10
Identities = 43/142 (30%), Positives = 72/142 (50%), Gaps = 9/142 (6%)
Query: 562 IKRVDNKEGYTCEKCKKVTNALKSNKIIRAPETLVVHLKKFRFNGTSSSKMKQAVSYPM- 620
++ ++ + + C CK+ A K + PE L++HLK+F + S K+ V +P+
Sbjct: 518 VETLEKENPWYCPSCKQHQLATKKLDLWMLPEILIIHLKRFSYTKFSREKLDTLVEFPIR 577
Query: 621 FLDLTEYC----HESISSLPVRYQLISVVVHEGRSLSSGHYIAH-CKQPDGSWATYDDEY 675
LD +E+ +ES L +Y LI+V H G + GHY C + G W +DD
Sbjct: 578 DLDFSEFVIQPQNESNPEL-YKYDLIAVSNHYG-GMRDGHYTTFACNKDSGQWHYFDDNS 635
Query: 676 INKISEKQLLKEPNAYFLVYTR 697
++ ++E Q ++ AY L Y R
Sbjct: 636 VSPVNENQ-IESKAAYVLFYQR 656
>ECU07g0410 [O] KOG1868 Ubiquitin C-terminal hydrolase
Length = 295
Score = 67.0 bits (162), Expect = 1e-10
Identities = 71/339 (20%), Positives = 143/339 (41%), Gaps = 55/339 (16%)
Query: 359 LKPRGLLNHGVTCYTNAAVQAMVHIPAIQHYLFQLLRGNF-KDTVKSNCVSMLLAETTMR 417
L P GL N G TC+ N+A+Q ++ I + + +F +D SN +AE
Sbjct: 10 LPPNGLRNKGNTCFFNSAMQCILSIGELNTFYKNT---DFPRDKPISNAFKQFIAE---- 62
Query: 418 MWSSDSTKNTYINPDKLINALEDINCMMSAWNQEDSHEYFMSLMSRLQEDSVPKGHKMTE 477
+ + + DKL ++ N M Q+DSHE+ + + L +S G+K
Sbjct: 63 -YETPGCHDPKSFIDKLSGRIKLFNGM-----QQDSHEFLIQFIDLLHNES--DGNKSR- 113
Query: 478 SIIYDVFGGLLQQSVKCSNCGEISTTEQPIYDLSLHLKGRKTTDQDQNSVGQDNSIDNSV 537
L+ + + S + ++ + + + + ++ +++I V
Sbjct: 114 ----------LESKDEFEEVRKHSLVAKTLFSMDKQVLTCEACNYSSVTIAMNSTI--LV 161
Query: 538 DQQQSSKRRFSIEKSIRDFFNPELIKRVDNKEGYTCEKCKKVTNALKSNKIIRAPETLVV 597
+ ++ ++ I ++ +++ K+ + C+KC + ++ K +++ P+ L+V
Sbjct: 162 EPYET------VQLGIDRYYEEV---KLEGKDAWRCDKCGRKESSRKRMEVLVHPDVLIV 212
Query: 598 HLKKFRFNGTSSSKMKQAVSYPMFLDLTEYCHESISSLPVRYQLISVVVHEGRSLSSGHY 657
H+ +F G ++ + +F + +Y L+ VV G +L+ GHY
Sbjct: 213 HISRFHPQGWKNTASVEVNDTLLFNNR-------------KYSLLGVVCQNG-TLNGGHY 258
Query: 658 IAHCKQPDGSWATYDDEYINKISEKQLLKEPNAYFLVYT 696
A K+ G+W Y+DE + K S P Y YT
Sbjct: 259 FAEAKR-SGTWNVYNDEQVTKGSRTYSGSHP--YIAFYT 294
>7302097 [O] KOG1866 Ubiquitin carboxyl-terminal hydrolase
Length = 2778
Score = 66.2 bits (160), Expect = 2e-10
Identities = 81/395 (20%), Positives = 141/395 (35%), Gaps = 111/395 (28%)
Query: 363 GLLNHGVTCYTNAAVQAMVHIPAIQHYLFQ-----------------LLRGNFKDTVKSN 405
GL N G TCY N+ +Q + +PA++ + + L G + S
Sbjct: 1669 GLKNAGATCYMNSVLQQLYMVPAVRVGILRAHGAATTDGEDFSGDSDLTGGGLGSALFSG 1728
Query: 406 CVSMLLA----ETTMRMWSSDSTKNTYINPDKLINAL----------------------- 438
S L++ +T+ D KN ++ K + A+
Sbjct: 1729 PASALVSLPSSSSTIEDGLHDVRKNYHVVILKHVQAIFAHLGHSALQYYVPRGLWTHFKL 1788
Query: 439 --EDINCMMSAWNQEDSHEYFMSLMSRLQEDSVPKGHKMTESIIYDVFGGLLQQSVKCSN 496
E +N Q+D+ E+FMSL+ L E G ++ GG C
Sbjct: 1789 LGEPVNLR----EQQDAVEFFMSLLESLDEGLKALGQ---PQLMNATLGGSFSDQKICQE 1841
Query: 497 CGEISTTEQPIYDLSLHLKGRKTTDQDQNSVGQDNSIDNSVDQQQSSKRRFSIEKSIRDF 556
C + E+P S+ ++ S+ +S+ +
Sbjct: 1842 CPHRYSKEEPFSVFSVDIRNHS-----------------------------SLTESLEQY 1872
Query: 557 FNPELIKRVDNKEGYTCEKCKKVTNALKSNKIIRAPETLVVHLKKFRFN--GTSSSKMKQ 614
EL++ D Y C+KC K +K + + P L + LK+F ++ + K
Sbjct: 1873 VKGELLEGAD---AYHCDKCDKKVVTVKRVCVKKLPPVLAIQLKRFEYDYERVCAIKFND 1929
Query: 615 AVSYPMFLDLTEYCHESISSL----------------PVRYQLISVVVHEGRSLSSGHYI 658
+P LD+ Y ++ L +Y+L +VVH G++ S GHY
Sbjct: 1930 YFEFPRILDMEPYTVSGLAKLEGEVVEVGDNCQTNVETTKYELTGIVVHSGQA-SGGHYF 1988
Query: 659 AH--CKQPDG---SWATYDDEYIN--KISEKQLLK 686
++ K P W +DD + K+ E + +K
Sbjct: 1989 SYILSKNPANGKCQWYKFDDGEVTECKMHEDEEMK 2023
>Hs10190742 [O] KOG1868 Ubiquitin C-terminal hydrolase
Length = 922
Score = 65.5 bits (158), Expect = 3e-10
Identities = 80/323 (24%), Positives = 130/323 (39%), Gaps = 68/323 (21%)
Query: 336 SINDHGSNKPQRIVKNWGSKLTQLKPRGLLNHGVTCYTNAAVQAMVHIPAIQHYLFQLLR 395
S D NK Q + + +L Q G N G TCY NA +Q++ IP+ L L +
Sbjct: 263 SQGDPRCNKAQVPLDSHSQQLQQ----GFPNLGNTCYMNAVLQSLFAIPSFADDL--LTQ 316
Query: 396 GNFKDTVKSNCVSMLLAE-TTMRMWSSDSTKNTYI-NPDKLINALEDINCMMSAWNQEDS 453
G + + + M L + ++ + S K + N K+I+A+ +I S Q D+
Sbjct: 317 GVPWEYIPFEALIMTLTQLLALKDFCSTKIKRELLGNVKKVISAVAEI---FSGNMQNDA 373
Query: 454 HEYFMSLMSRLQED------------------SVPK---GHKMTESIIYDVFGGL---LQ 489
HE+ + +L+ED S P+ G T+ + V LQ
Sbjct: 374 HEFLGQCLDQLKEDMEKLNATLNTGKECGDENSSPQMHVGSAATKVFVCPVVANFEFELQ 433
Query: 490 QSVKCSNCGEISTTEQPIYDLSLHLKGRKTTDQDQNSVGQDNSIDNSVDQQQSSKRRFSI 549
S+ C CG +P LS++L Q++ SI
Sbjct: 434 LSLICKACGHAVLKVEPNNYLSINL------------------------HQETKPLPLSI 469
Query: 550 EKSIRDFFNPELIKRVDNKEGYTCEKCKKVTNALKSNKIIRAPETLVVHLKKFRFNGT-S 608
+ S+ FF E ++ Y C+ CK+ + + + R L++HLK++ FN
Sbjct: 470 QNSLDLFFKEEELE-------YNCQMCKQ-KSCVARHTFSRLSRVLIIHLKRYSFNNAWL 521
Query: 609 SSKMKQAVSYPMFLDLTEYCHES 631
K + V P L L+ YC+ES
Sbjct: 522 LVKNNEQVYIPKSLSLSSYCNES 544
>Hs22047537 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 248
Score = 65.1 bits (157), Expect = 4e-10
Identities = 43/166 (25%), Positives = 75/166 (44%), Gaps = 17/166 (10%)
Query: 363 GLLNHGVTCYTNAAVQAMVHIPAIQHYLFQLLRGNFKDTVKSNCVSMLLAETTMRMWSSD 422
GL N G TCY NA++Q + + P + +Y+ L T + ML W
Sbjct: 81 GLQNMGNTCYVNASLQCLTYTPPLANYM---LSREHSQTCHRHKCCMLCTMQAHITWPLH 137
Query: 423 STKNTYINPDKLINALEDINCMMSAWNQEDSHEYFMSLMSRLQEDSVPKGHKMTES---- 478
S P +I + + QED+HE+ M + +++ +P GHK ++
Sbjct: 138 S-------PGHVIQPSQVLAAGFHRGEQEDAHEFLMFTVDAMKKAFLP-GHKHLDNHSKD 189
Query: 479 --IIYDVFGGLLQQSVKCSNCGEISTTEQPIYDLSLHLKGRKTTDQ 522
+I+ +FGG + + C +C IS T P D++L ++ ++ Q
Sbjct: 190 TTLIHQIFGGYWRSHINCFHCHGISDTFDPYLDIALDIQAAQSVKQ 235
>CE29636 [O] KOG1870 Ubiquitin C-terminal hydrolase
Length = 1119
Score = 65.1 bits (157), Expect = 4e-10
Identities = 48/175 (27%), Positives = 86/175 (48%), Gaps = 16/175 (9%)
Query: 529 QDNSIDNSVDQQQSSKRRF---SIEKSIRDFFNPELIKRVDNKEGYTCEKCKKVTNALKS 585
Q+ + ++ ++ R F S+E I F PE + C++C+K T K
Sbjct: 951 QEQACEDDPSVAETWSRHFAPSSLEHCIEKFSCPETLDAA-----IQCDRCEKKTMRDKV 1005
Query: 586 NKIIRAPETLVVHLKKFRF--NGTSSSKMKQAVSYPM-FLDLTEYCHESISSLPVRYQLI 642
I + P+ L++HLK+F F K K+ V++P+ D + + + Y+ I
Sbjct: 1006 MTIWKLPKYLIIHLKRFEFLREQGRMGKCKRTVNFPLKHFDPAPFVDKPDGN---TYECI 1062
Query: 643 SVVVHEGRSLSSGHYIAHCKQPDGSWATYDDEYINKISEKQLLKEPNAYFLVYTR 697
++ H G+ LS GH+IA+ K + W +D + ++SE+++ K+ AY L Y R
Sbjct: 1063 ALANHYGQ-LSCGHFIAYAKSNEDKWLLLNDCSVREVSEEEVDKQ-GAYLLFYER 1115
>CE29635 [O] KOG1870 Ubiquitin C-terminal hydrolase
Length = 1116
Score = 65.1 bits (157), Expect = 4e-10
Identities = 48/175 (27%), Positives = 86/175 (48%), Gaps = 16/175 (9%)
Query: 529 QDNSIDNSVDQQQSSKRRF---SIEKSIRDFFNPELIKRVDNKEGYTCEKCKKVTNALKS 585
Q+ + ++ ++ R F S+E I F PE + C++C+K T K
Sbjct: 948 QEQACEDDPSVAETWSRHFAPSSLEHCIEKFSCPETLDAA-----IQCDRCEKKTMRDKV 1002
Query: 586 NKIIRAPETLVVHLKKFRF--NGTSSSKMKQAVSYPM-FLDLTEYCHESISSLPVRYQLI 642
I + P+ L++HLK+F F K K+ V++P+ D + + + Y+ I
Sbjct: 1003 MTIWKLPKYLIIHLKRFEFLREQGRMGKCKRTVNFPLKHFDPAPFVDKPDGN---TYECI 1059
Query: 643 SVVVHEGRSLSSGHYIAHCKQPDGSWATYDDEYINKISEKQLLKEPNAYFLVYTR 697
++ H G+ LS GH+IA+ K + W +D + ++SE+++ K+ AY L Y R
Sbjct: 1060 ALANHYGQ-LSCGHFIAYAKSNEDKWLLLNDCSVREVSEEEVDKQ-GAYLLFYER 1112
>HsM4507851 [O] KOG1864 Ubiquitin-specific protease
Length = 785
Score = 64.3 bits (155), Expect = 7e-10
Identities = 47/194 (24%), Positives = 89/194 (45%), Gaps = 23/194 (11%)
Query: 479 IIYDVFGGLLQQSVKCSNCGEISTTEQPIYDLSLHLKGRKTTDQDQNSVGQDNSIDNSVD 538
++ +F G L +C C ++ + D+S+ ++ +D+ S +++S +
Sbjct: 425 LVEKLFQGQLVLRTRCLECESLTERREDFQDISVPVQ------EDELSKVEESSEISPEP 478
Query: 539 QQQSSKRRFSIEKSIRDFFNPELIKRVDNKEGYTCEKCKKVTNALKSNKIIRAPETLVVH 598
+ + R++I + ++R+ ++ Y CE C T A +S + PE + +H
Sbjct: 479 KTEMKTLRWAISQFAS-------VERIVGEDKYFCENCHHYTEAERSLLFDKMPEVITIH 531
Query: 599 LKKFRFNGT-------SSSKMKQAVSYPMFLDLTEYCHESISSLPVRYQLISVVVHEGRS 651
LK F +G SK+ + P+ L L E+ + + Y L +VV+H G +
Sbjct: 532 LKCFAASGLEFDCYGGGLSKINTPLLTPLKLSLEEWSTKPTND---SYGLFAVVMHSGIT 588
Query: 652 LSSGHYIAHCKQPD 665
+SSGHY A K D
Sbjct: 589 ISSGHYTASVKVTD 602
>Hs21361110 [O] KOG1864 Ubiquitin-specific protease
Length = 785
Score = 64.3 bits (155), Expect = 7e-10
Identities = 47/194 (24%), Positives = 89/194 (45%), Gaps = 23/194 (11%)
Query: 479 IIYDVFGGLLQQSVKCSNCGEISTTEQPIYDLSLHLKGRKTTDQDQNSVGQDNSIDNSVD 538
++ +F G L +C C ++ + D+S+ ++ +D+ S +++S +
Sbjct: 425 LVEKLFQGQLVLRTRCLECESLTERREDFQDISVPVQ------EDELSKVEESSEISPEP 478
Query: 539 QQQSSKRRFSIEKSIRDFFNPELIKRVDNKEGYTCEKCKKVTNALKSNKIIRAPETLVVH 598
+ + R++I + ++R+ ++ Y CE C T A +S + PE + +H
Sbjct: 479 KTEMKTLRWAISQFAS-------VERIVGEDKYFCENCHHYTEAERSLLFDKMPEVITIH 531
Query: 599 LKKFRFNGT-------SSSKMKQAVSYPMFLDLTEYCHESISSLPVRYQLISVVVHEGRS 651
LK F +G SK+ + P+ L L E+ + + Y L +VV+H G +
Sbjct: 532 LKCFAASGLEFDCYGGGLSKINTPLLTPLKLSLEEWSTKPTND---SYGLFAVVMHSGIT 588
Query: 652 LSSGHYIAHCKQPD 665
+SSGHY A K D
Sbjct: 589 ISSGHYTASVKVTD 602
>Hs14777500 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase
Length = 284
Score = 64.3 bits (155), Expect = 7e-10
Identities = 39/145 (26%), Positives = 69/145 (46%), Gaps = 11/145 (7%)
Query: 543 SKRRFSIEKSIRDFFNPELIKRVDNKEGYTCEKCKKVTNALKSNKIIRAPETLVVHLKKF 602
SK ++E ++ FF P + + +K CE C K T + K+ P+TL +HL +F
Sbjct: 129 SKPLKTLEDALHCFFQP---RELSSKSKCFCENCGKKTRGKQVLKLTHLPQTLTIHLMRF 185
Query: 603 RFNGTSSSKMKQAVSYPMFLDLTEYCHESISSLPV------RYQLISVVVHEGRSLSSGH 656
+ + K+ ++ +P LD ++ S +Y+L +V+ H G + SGH
Sbjct: 186 SIRNSQTRKICHSLYFPQSLDFSQILPMKRESCDAEEQSGGQYELFAVIAHVGMA-DSGH 244
Query: 657 YIAHCKQP-DGSWATYDDEYINKIS 680
Y + + DG W ++D I +S
Sbjct: 245 YCVYIRNAVDGKWFCFNDSNICLVS 269
>At1g32850 [O] KOG1870 Ubiquitin C-terminal hydrolase
Length = 887
Score = 63.9 bits (154), Expect = 8e-10
Identities = 55/186 (29%), Positives = 78/186 (41%), Gaps = 32/186 (17%)
Query: 363 GLLNHGVTCYTNAAVQAMVHIPAIQHYLFQLLRG--NFKDTVKSNC-VSMLLAETTMRMW 419
GL N G TC+ N+ +Q + H P I Y Q R N K+ + +++ E ++W
Sbjct: 297 GLQNLGNTCFMNSTLQCLAHTPPIVEYFLQDYRSDINAKNPLGMRGELAIAFGELLRKLW 356
Query: 420 SSDSTKNTYINPDKLINALEDINCMMSAWNQEDSHEYFMSLMSRLQEDSVP--------- 470
SS +NT + P L S +NQ DS E L+ L ED
Sbjct: 357 SSG--QNT-VAPRAFKTKLARFAPQFSGYNQHDSQEMLAFLLDGLHEDLNKVKRKPYIEA 413
Query: 471 ----------------KGHKM-TESIIYDVFGGLLQQSVKCSNCGEISTTEQPIYDLSLH 513
K HK +S+I DVF G + ++ C +CG+IS T P LSL
Sbjct: 414 KDSDGRPDDEVAEEKWKYHKARNDSVIVDVFQGQYKSTLVCPDCGKISITFDPFMYLSLP 473
Query: 514 LKGRKT 519
L +T
Sbjct: 474 LPSSRT 479
Score = 60.5 bits (145), Expect = 9e-09
Identities = 40/132 (30%), Positives = 69/132 (51%), Gaps = 5/132 (3%)
Query: 573 CEKCKKVTNALKSNKIIRAPETLVVHLKKFRFNGTSSSKMKQAVSYPMF-LDLTEYCHES 631
C CK+ A K + + P+ LV HLK+F ++ +K+ V++ + LDL++Y ++
Sbjct: 751 CPGCKEHRQANKKLDLWKLPDILVFHLKRFTYSRYFKNKIDTLVNFHIHDLDLSKYV-KN 809
Query: 632 ISSLPVRYQLISVVVHEGRSLSSGHYIAHCKQPDGS-WATYDDEYINKISEKQLLKEPNA 690
Y+L ++ H G L GHY A+ K D + W +DD ++ ++E + +K A
Sbjct: 810 EDGQSYLYELYAISNHYG-GLGGGHYTAYAKLMDETKWYNFDDSRVSAVNESE-IKTSAA 867
Query: 691 YFLVYTRLTPKS 702
Y L Y R+ S
Sbjct: 868 YVLFYQRVKSDS 879
>Hs22056581 [O] KOG1868 Ubiquitin C-terminal hydrolase
Length = 493
Score = 63.5 bits (153), Expect = 1e-09
Identities = 43/122 (35%), Positives = 63/122 (51%), Gaps = 5/122 (4%)
Query: 581 NALKSNKIIRAPETLVVHLKKFRFNGTSSSKMKQAVSYPM-FLDLTEYCHESISSLPVRY 639
+ + +I + P L+VHLK F +NG K++ +V +P+ L L++Y ++L Y
Sbjct: 375 DGILKKEIWKLPPVLLVHLKHFSYNGRWKQKLQTSVDFPLENLALSQYVIGPKNNLK-NY 433
Query: 640 QLISVVVHEGRSLSSGHYIAHCKQ-PDGSWATYDDEYINKISEKQLLKEPNAYFLVYTRL 698
L SV H G L GHY A+CK W +DD ++ IS +K AY L YT L
Sbjct: 434 NLFSVSDHCG-GLDGGHYTAYCKNAAKQRWFKFDDHEVSDISVSS-VKSSAAYILFYTSL 491
Query: 699 TP 700
P
Sbjct: 492 GP 493
>SPCC1494.05c [O] KOG1870 Ubiquitin C-terminal hydrolase
Length = 979
Score = 61.2 bits (147), Expect = 6e-09
Identities = 47/172 (27%), Positives = 76/172 (43%), Gaps = 13/172 (7%)
Query: 534 DNSVDQQQSSKRRFSIEKSIRDFFNPELIKRVDNKEGYTCEKCKKVTNALKSNKIIRAPE 593
D D + S R ++ + +F E +++ ++ + C CK+ A K +I R PE
Sbjct: 814 DKKDDSEDS--RTITLNDCLDEF---EKTEQLGEEDPWYCPTCKEFRQASKQMEIWRCPE 868
Query: 594 TLVVHLKKFRFNGTSSSKMKQAVSYP-----MFLDLTEYCHESISSLPVRYQLISVVVHE 648
L+ HLK+F K+ V +P M + Y + + Y+L +V H
Sbjct: 869 ILIFHLKRFSSERRFRDKIDDLVEFPIDNLDMSMRTGSYKLSEKENPKLIYELYAVDNHY 928
Query: 649 GRSLSSGHYIAHCKQPD-GSWATYDDEYINKISEKQLLKEPNAYFLVYTRLT 699
G L GHY A K PD G + +DD + + ++ + AY L Y R T
Sbjct: 929 G-GLGGGHYTAFAKNPDNGQFYCFDDSRVTPVCPEETVTSA-AYLLFYRRKT 978
>ECU03g0580 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase
Length = 933
Score = 61.2 bits (147), Expect = 6e-09
Identities = 74/357 (20%), Positives = 141/357 (38%), Gaps = 77/357 (21%)
Query: 363 GLLNHGVTCYTNAAVQAMVHIPAIQHYLFQL-LRGNFKDTVKSNCVSMLLAETTMRMWSS 421
GL N G TCY N+ +QA+ I ++ +F L RG +LL + M +
Sbjct: 112 GLRNLGATCYINSLMQALFSIAKFRNDVFGLEPRGRV----------LLLQKLFKEMQTG 161
Query: 422 DSTKNTYINPDKLINAL--EDINCMMSAWNQEDSHEYFMSLMSRLQEDSVPKGHKMTESI 479
+ +T D ++N + +D++ +D HE+ L++DS K +
Sbjct: 162 EHPVDT---TDFVVNNIWVDDVHV------HQDIHEFSKVFFDSLEKDSKRK------DV 206
Query: 480 IYDVFGGLLQQSVKCSNCGEISTTEQPIYDLSLHLKGRKTTDQDQNSVGQDNSIDNSVDQ 539
I D+ G L + CG + ++ D+ + ++
Sbjct: 207 IEDMIQGELVTYIN-GKCGCVRRIKEKFQDIQVEIR-----------------------D 242
Query: 540 QQSSKRRFSIEKSIRDFFNPELIKRVDNKEGYTCEKCKKVTNALKSNKIIRAPETLVVHL 599
++K ++++S++ + E++ D Y CEK + +A K P + + L
Sbjct: 243 FFNNKLSSNLQESLKRYVKSEIL---DGNNRYNCEK-HGLVDAKKGVMFSSLPPVMFILL 298
Query: 600 KKFR--FNGTSSSKMKQAVSYPMFLDLTEYCHESI---SSLPVRYQLISVVVHEGRSLSS 654
K+F F + K+ +P +D+ + Y L SV+VH G
Sbjct: 299 KRFNVDFETGNGYKINDYFEFPDSIDMLPFLDRDSKRKEESDATYDLYSVIVHRG-DHDE 357
Query: 655 GHYIAHCKQPDGSWATYDDEYINKISE--------------KQLLKEPNAYFLVYTR 697
GH+ A+ K +G W ++D + + E K +++ + Y+L+Y R
Sbjct: 358 GHFYAYLK-INGRWLKFNDTVVTEAGEMEALEHNFGGRHPYKDRIRDHSGYYLIYLR 413
>CE13299 [O] KOG4598 Putative ubiquitin-specific protease
Length = 1292
Score = 60.8 bits (146), Expect = 7e-09
Identities = 51/188 (27%), Positives = 81/188 (42%), Gaps = 35/188 (18%)
Query: 447 AWNQEDSHEYFMSLMSRLQEDSVPKGHKMTE--SIIYDVFGGLLQQSVKCSNCGEISTTE 504
A++Q D E + RL D++ K TE +I D++ G ++ V C CG S
Sbjct: 140 AYDQHDVQE-----LCRLMFDALEHKWKGTEHEKLIQDLYRGTMEDFVACLKCGRESVKT 194
Query: 505 QPIYDLSLHLKGRKTTDQDQNSVGQDNSIDNSVDQQQSSKRRFSIEKSIRDFFNPELIKR 564
DL L +K G ++ S+E+++ F PEL+
Sbjct: 195 DYFLDLPLAVK----------PFGAIHAYK-------------SVEEALTAFVQPELL-- 229
Query: 565 VDNKEGYTCEKCKKVTNALKSNKIIRAPETLVVHLKKFRF--NGTSSSKMKQAVSYPMFL 622
D Y CE CK +A K +I + P L + LK+F F N K+ +++P L
Sbjct: 230 -DGSNQYMCENCKSKQDAHKGLRITQFPYLLTIQLKRFDFDYNTMHRIKLNDKMTFPDVL 288
Query: 623 DLTEYCHE 630
DL +Y ++
Sbjct: 289 DLNDYVNK 296
>CE03146 [O] KOG1870 Ubiquitin C-terminal hydrolase
Length = 1095
Score = 60.8 bits (146), Expect = 7e-09
Identities = 58/214 (27%), Positives = 91/214 (42%), Gaps = 28/214 (13%)
Query: 529 QDNSIDNSVDQQQSSKRRFSIEKSIRDFFNPELIKRVD---------NKEGYTCEKCKKV 579
+D +D +Q +S+ KS NP L + +D +E + C CK+
Sbjct: 878 KDIDVDVEKSRQMNSRNMNGYVKSNNSETNPHLTQMLDLFSETERLKPEESWYCSTCKEN 937
Query: 580 TNALKSNKIIRAPETLVVHLKKFRFNG-------TSSSKMKQAVSYPM-FLDLTEYCHE- 630
A K ++ R P L++ LK+F + SK ++V YP+ LD++ + E
Sbjct: 938 VEATKKLQLYRLPPVLIIQLKRFVYTAFTYQSSMARRSKDTRSVEYPLESLDMSPFLAET 997
Query: 631 SISSLPVRYQLISVVVHEGRSLSSGHYIAHCKQPDG-------SWATYDDEYINKISEKQ 683
S Y L VV H G S GHYI+ + D W +DD + + S
Sbjct: 998 SPHPNSTMYDLTGVVCHSGNSY-FGHYISMGRLADFDSSKTKIEWRNFDDSTVARQSTST 1056
Query: 684 LLKEPNAYFLVYTRLTPKSVPLSSQSSNKSTDLG 717
L E +AY L Y ++ ++V S + S D G
Sbjct: 1057 LQTE-DAYLLFY-KMRDQNVTRSIFKRHYSCDPG 1088
>At2g32780 [O] KOG1873 Ubiquitin-specific protease
Length = 1083
Score = 60.8 bits (146), Expect = 7e-09
Identities = 48/184 (26%), Positives = 78/184 (42%), Gaps = 18/184 (9%)
Query: 362 RGLLNHGVTCYTNAAVQAMVHIPAIQHYLFQLLRGNFKDTVKSNCVSMLLAETTMRMWSS 421
RGL+N G TC+ N+ +Q ++ + ++ + + +D S + L E S
Sbjct: 202 RGLVNLGNTCFFNSVMQNLLSLDQLREHFLK------EDLSVSGPLVSSLKELFAESNSE 255
Query: 422 DSTKNTYINPDKLINALEDINCMMSAWNQEDSHEYFMSLMSRL--QEDSVPKGHKMTES- 478
S INP L ++ + Q DSHE L+ L +E S+ K +++S
Sbjct: 256 ASVFRNEINPRDLFFSVCSQAPQFRGYQQHDSHELLRCLLDGLSIEESSLRKKLGVSDSN 315
Query: 479 ---------IIYDVFGGLLQQSVKCSNCGEISTTEQPIYDLSLHLKGRKTTDQDQNSVGQ 529
+I VFGG + +V C CG S +P DLSL + K + Q + Q
Sbjct: 316 DSSTYQKPTLIDSVFGGEISSTVSCLECGHFSKVYEPFMDLSLPVPSMKLPPKKQQILSQ 375
Query: 530 DNSI 533
+
Sbjct: 376 AKEV 379
>CE19500 [O] KOG1870 Ubiquitin C-terminal hydrolase
Length = 900
Score = 60.1 bits (144), Expect = 1e-08
Identities = 46/159 (28%), Positives = 81/159 (50%), Gaps = 8/159 (5%)
Query: 542 SSKRRFSIEKSIRDFFNPELIKRVDNKEGYTCEKCKKVTNALKSNKIIRAPETLVVHLKK 601
S++R+ +++++ D+F + +++ ++ + C +CKK A K + + PE L++HLK+
Sbjct: 693 STRRKVLLQETL-DWFTTK--EQLGEQDSWYCPQCKKHERATKQLALWKLPEILILHLKR 749
Query: 602 FRFNGTSSSKMKQAVSYPM-FLDLTEYCHESISSLPVRYQLISVVVHEGRSLSSGHYIA- 659
F++ S K+ V P+ LDLT+ + Y LI+V H G SLS GHY A
Sbjct: 750 FQYTKWSREKLTWEVVIPVRGLDLTDKVANPNHEKAI-YDLIAVSRHYG-SLSGGHYTAI 807
Query: 660 HCKQPDGSWATYDDEYIN-KISEKQLLKEPNAYFLVYTR 697
+ W ++D N + + + Y LVY R
Sbjct: 808 GYNDREQKWFDFNDSSANPTYPPAEPYESSDPYILVYRR 846
>At3g21280 [O] KOG1872 Ubiquitin-specific protease
Length = 488
Score = 60.1 bits (144), Expect = 1e-08
Identities = 72/355 (20%), Positives = 142/355 (39%), Gaps = 50/355 (14%)
Query: 363 GLLNHGVTCYTNAAVQAMVHIPAIQHYLFQLLRGNFKDTVKSNCVSMLLAETTMRMWSSD 422
GL+N G TCY N+ +Q ++ +P ++ L KD ++ S +L T ++S
Sbjct: 105 GLVNLGNTCYMNSTMQCLISVPELKSELSNYQSARTKDVDQT---SHMLTVATRELFSEL 161
Query: 423 STKNTYINPDKLINALEDINCMMSAWN-----QEDSHEYFMSLMSRLQEDSVPKGHKMTE 477
+ P L+ + + Q+D+ E + ++ L +
Sbjct: 162 DKSVKAVAPMPFWMVLQKKYPQFAQLHNGNHMQQDAEECWTQMLYTLSQSLKLPSPSEDP 221
Query: 478 SIIYDVFGGLLQQSVKCSNCGEISTTEQPIYDLSLH---------------LKGR--KTT 520
+ +FG L + C E S+ + ++ L H LKG KT+
Sbjct: 222 DAVKALFGLNLLNRLHCQESSEESSETESVFSLKCHISHEVNHLHEGLKHGLKGELEKTS 281
Query: 521 DQ-DQNSVGQDNSIDNSVDQ------------QQSSKRR-------FSIEKSIRDFFNPE 560
+ +V S+ +S+ + ++S+++ + +E I D + +
Sbjct: 282 PSLGRTAVYVKESLIDSLPRYLTVQFVRFFWKRESNQKAKILRKVDYPLELDIYDLCSED 341
Query: 561 LIKRVDN-KEGYTCEKCKKVTNALKSNKIIRAPETLVVHLK-KFRFNGTSSSKMKQAVSY 618
L K+++ ++ + +K+ + + + + + +G SS+ +Q VS
Sbjct: 342 LRKKLEAPRQKLRDIEGQKLGLQASAKSSSKGDDVKMTDAEGSSNQSGESSTGDQQEVSI 401
Query: 619 PMFLDLTEYCHESISSLPVRYQLISVVVHEGRSLSSGHYIAHCKQPDGSWATYDD 673
+ ++ + Y L+SV+ H+GRS SGHY+A KQ G W YDD
Sbjct: 402 SLLQTFATGASPHMTGI---YDLVSVLTHKGRSADSGHYVAWVKQESGKWVQYDD 453
>Hs22063256 [O] KOG1870 Ubiquitin C-terminal hydrolase
Length = 675
Score = 59.7 bits (143), Expect = 2e-08
Identities = 48/202 (23%), Positives = 86/202 (41%), Gaps = 30/202 (14%)
Query: 534 DNSVDQQQSSKRRFSIEKSIRDFFNPELIKRVDNKEGYTCEKCKKVTNALKSNKIIRAPE 593
D+ QQQ+ ++ F+ E +++ + + C C+ + + + P+
Sbjct: 215 DSVWQQQQAHQQHSCTLDECFQFYTKE--EQLAQDDAWKCPHCQVLQQGMVKLSLWTLPD 272
Query: 594 TLVVHLKKFRFNGTSSSKMKQAVSYPMF-LDLTEY----------------------CHE 630
L++HLK+F G +K+ V +P+ L++ + C
Sbjct: 273 ILIIHLKRFCQVGERRNKLSTLVKFPLSGLNMAPHVAQRSTSPEAGLGPWPSWKQPDCLP 332
Query: 631 SISSLPVRYQLISVVVHEGRSLSSGHYIAHCKQP-DGSWATYDDEYINKISEKQLLKEPN 689
+ L Y L +V H G +L GHY A+C+ DG W +YDD + + E + +
Sbjct: 333 TSYPLDFLYDLYAVCNHHG-NLQGGHYTAYCRNSLDGQWYSYDDSTVEPLREDE-VNTRG 390
Query: 690 AYFLVYTRLTPKSVPLSSQSSN 711
AY L Y + S+P S SS+
Sbjct: 391 AYILFYQK--RNSIPPWSASSS 410
>At1g51710 [O] KOG1872 Ubiquitin-specific protease
Length = 490
Score = 59.7 bits (143), Expect = 2e-08
Identities = 82/380 (21%), Positives = 142/380 (36%), Gaps = 72/380 (18%)
Query: 363 GLLNHGVTCYTNAAVQAMVHIPAIQHYLFQLLRGNFKDTVKSNCV---SMLLAETTMRMW 419
GL+N G TCY N+ VQ + +P ++ L N+ +SN V S +L T ++
Sbjct: 105 GLVNLGNTCYMNSTVQCLKSVPELKSAL-----SNYSLAARSNDVDQTSHMLTVATRELF 159
Query: 420 SS---DSTKNTYINPDKLINALEDINCMMSAWNQEDSHEYFMSLMSRLQEDSVPKGHKMT 476
+ Y +L N + Q+D+ E + L+ L +
Sbjct: 160 GELDRSVLRKKYPQFSQLQNGMH---------MQQDAEECWTQLLYTLSQSLKAPTSSEG 210
Query: 477 ESIIYDVFGGLLQQSVK-------------------CSNCGEISTTEQPIYDLSLHLKGR 517
+ +FG LQ +K C GE S+ + +Y L H+
Sbjct: 211 ADAVKALFGVNLQSRIKLGVLDNVTDSTVISKCTLHCQESGEESSETESVYSLKCHISHE 270
Query: 518 KTTDQDQNSVGQDNSIDNSV-----------DQQQSSKRRFSIEKSIRDFFNPE------ 560
+ G ++ + + S R+ + +R F+ E
Sbjct: 271 VNHLHEGLKHGLKGELEKTSPALGRTALYVKESLIDSLPRYLTVQFVRFFWKRESNQKAK 330
Query: 561 LIKRVD-----NKEGYTCEKCKKVTNALKSNKIIRAPETLVVHLKKFRFNGTSSSKMK-- 613
++++VD + E +K A + +R E + L+ +G+ S +K
Sbjct: 331 ILRKVDYPLVLDIFDLCSEDLRKKLEAPRQK--LREEEGKKLGLQTSAKSGSKDSDVKMT 388
Query: 614 --QAVSYPMFLDLTEYCHESISS-----LPVRYQLISVVVHEGRSLSSGHYIAHCKQPDG 666
+A + T E SS + Y L++V+ H+GRS SGHY+A KQ G
Sbjct: 389 DAEASANGSGESSTVNPQEGTSSEKETHMTGIYDLVAVLTHKGRSADSGHYVAWVKQESG 448
Query: 667 SWATYDDEYINKISEKQLLK 686
W YDD+ + E+ + K
Sbjct: 449 KWIQYDDDNPSMQREEDITK 468
>SPCC16A11.12c [O] KOG1870 Ubiquitin C-terminal hydrolase
Length = 849
Score = 58.5 bits (140), Expect = 4e-08
Identities = 48/160 (30%), Positives = 82/160 (51%), Gaps = 17/160 (10%)
Query: 548 SIEKSIRDFFNPELIKRVDNKEGYTCEKCKKVTNALKSNKIIRAPETLVVHLKKFRFNG- 606
++E + +F PE ++D ++ + C CK A K +I R P+ LV+HL +F +G
Sbjct: 691 TLEDCLLEFSKPE---QLDLQDSWYCPGCKAFRPATKRLEIWRLPKILVIHLNRFSGHGG 747
Query: 607 --TSSSKMKQAVSYPMF-LDLTEYC------HESISS-LPVRYQLISVVVHEGRSLSSGH 656
K + V YP+F L+L ++ HE +SS + Y L +V H G +S+GH
Sbjct: 748 DLRRRRKRRDLVVYPVFDLNLKQFLSPFIKDHEWLSSQKSMLYDLYAVDNHHG-FMSNGH 806
Query: 657 YIAHCKQPDG-SWATYDDEYINKISEKQLLKEPNAYFLVY 695
Y A+ + ++ +DD I +I + ++ +AY L Y
Sbjct: 807 YTAYARDASSQTFFKFDDTAICEIDPEDIVTS-SAYVLFY 845
>Hs5454156 [O] KOG1873 Ubiquitin-specific protease
Length = 823
Score = 57.4 bits (137), Expect = 8e-08
Identities = 41/147 (27%), Positives = 63/147 (41%), Gaps = 30/147 (20%)
Query: 580 TNALKSNKIIRAPETLVVHLKKFRFNGTSSSKMKQAVSYPMFLDLTEYC-----HESISS 634
TNA K I AP L +HLK+F+ G + K+ + + +P LDL +C + + +
Sbjct: 678 TNAKKQMLISLAPPVLTLHLKRFQQAGFNLRKVNKHIKFPEILDLAPFCTLKCKNVAEEN 737
Query: 635 LPVRYQLISVVVHEGRSLSSGHYIAHCK-----------------------QPDGSWATY 671
V Y L VV H G ++ SGHY A+ K + G W
Sbjct: 738 TRVLYSLYGVVEHSG-TMRSGHYTAYAKARTANSHLSNLVLHGDIPQDFEMESKGQWFHI 796
Query: 672 DDEYINKISEKQLLKEPNAYFLVYTRL 698
D ++ + ++L AY L Y R+
Sbjct: 797 SDTHVQAVPTTKVLNS-QAYLLFYERI 822
>7290583 [O] KOG1873 Ubiquitin-specific protease
Length = 1126
Score = 57.4 bits (137), Expect = 8e-08
Identities = 58/204 (28%), Positives = 86/204 (41%), Gaps = 44/204 (21%)
Query: 548 SIEKSIRDFFNPELIKRVDNKEGYTCEKC-----------KKV-TNALKSNKIIRAPETL 595
S++ + +F EL+ NK G C+ C K V TNA K + P L
Sbjct: 859 SVQSCLNNFTAVELMTG-QNKVG--CDSCTQRINGSDPKAKSVNTNATKQLLVSSPPAVL 915
Query: 596 VVHLKKFRFNGTSS-SKMKQAVSYPMFLDLTEYCHESISSLP--------VRYQLISVVV 646
++HLK+F+ K+ + VSYP LD+ +C + +LP + Y L VV
Sbjct: 916 ILHLKRFQLGPRCIFRKLTRPVSYPNLLDIAAFCGSKVKNLPNIDRKQKKLLYALYGVVE 975
Query: 647 HEGRSLSSGHYIAHCK--------------QPDGSWA--TYDDEYINKISEKQLLKEPNA 690
H G + GHY A+ K P GS A DD+ + K+ E ++
Sbjct: 976 HSG-GMYGGHYTAYVKVRPKVAPGDKRWKFLPHGSKAELDQDDDQLKKLEELLAKEKARE 1034
Query: 691 YFLVYTRLTPKSVPLSSQSSNKST 714
L ++ S S+ SSN ST
Sbjct: 1035 QHL---KVLDDSDDFSNSSSNSST 1055
>YKR098c [O] KOG1868 Ubiquitin C-terminal hydrolase
Length = 717
Score = 57.0 bits (136), Expect = 1e-07
Identities = 89/433 (20%), Positives = 157/433 (35%), Gaps = 91/433 (21%)
Query: 348 IVKNWGSKLTQLKPRGLLNHGVTCYTNAAVQAMVHIPAIQHYLFQLLRGNFKDTVKSNCV 407
++++ L++L GL N TCY N+ +Q + + F +T K
Sbjct: 284 VIEDSNDLLSELSITGLQNPCNTCYINSIIQCLFGTTLFRDLFLTKKYRLFLNTNKYPKE 343
Query: 408 SMLLAETTMRMWSSDSTKNTYINPDKLINALEDINCMMSAWN-QEDSHEYFMSLMSRLQE 466
L + I P++ + + + ++ + Q+D+ E+ + +++R+ E
Sbjct: 344 VQLSRSIYVLFKKMYLNGGRAIIPNRFLKMCKKLRPDLNIPDDQQDTQEFLLIVLARIHE 403
Query: 467 D-----------------------SVPKGHKMTE--------SIIYDVFGGLLQQSVKCS 495
+ + K K E S I ++ G L+ +KC
Sbjct: 404 ELSNENVVKYYPDLVSYDANALQVNPSKYEKWYERNVITDGLSPIDHIYRGQLENILKCQ 463
Query: 496 NCGEISTTEQPIYDLSLHL----------KGRKTTDQD-------QNSVGQDNSID---N 535
CG S + Y LSL + K RK +D + DN+ D
Sbjct: 464 RCGNSSYSYSTFYVLSLAIPKLSLYSFTSKSRKIKLEDCINLFTGDEELSGDNAWDCPNC 523
Query: 536 SVDQQQSSKRRFSIEKSIRDFFNPELIKRV--------------DNKEGYTCEKCKKVTN 581
+ +S K + +K F R D+ + KK+T
Sbjct: 524 RITDSKSKKEEITSQKKKSTIFGFHSRSRSKSPHHHHHHHHSSDDSTKNAKKRNSKKLT- 582
Query: 582 ALKSNKIIRAPETLVVHLKKFRFNGTSSSKMKQAVSYPMFLDLTEYCHESISSLPVRYQL 641
+KS I P LV+HL +F ++ T K ++YP+ L++ + +RY+L
Sbjct: 583 TIKSLDFIVLPPILVIHLSRFYYDLT--KKNSTVITYPLILNII-----LKNGKVIRYKL 635
Query: 642 ISVVVHEGRSLSSGHYIAHCKQPDGS--------WATYDDEYI--------NKISEKQLL 685
V H G +L +GHY + + W T+DD+YI N + K +
Sbjct: 636 YGTVNHSG-NLINGHYTSVVNKEKSHEIGLNRQVWVTFDDDYIQQHRKDRNNFEAGKTEM 694
Query: 686 KEPNAYFLVYTRL 698
Y L Y R+
Sbjct: 695 SSDEVYVLFYERM 707
>Hs13994268 [O] KOG1868 Ubiquitin C-terminal hydrolase
Length = 913
Score = 57.0 bits (136), Expect = 1e-07
Identities = 76/314 (24%), Positives = 134/314 (42%), Gaps = 46/314 (14%)
Query: 363 GLLNHGVTCYTNAAVQAMVHIPAIQHYLFQLLRGNFK-DTVKSNCVSMLLAETTMRMWSS 421
GL N G TCY NA +Q+++ IP+ + LL +F + N ++M LA R+
Sbjct: 296 GLPNLGNTCYMNAVLQSLLSIPS---FADDLLNQSFPWGKIPLNALTMCLA----RLLFF 348
Query: 422 DSTKNTYINPDKLINALEDINCMMSAWN---QEDSHEYFMSLMSRLQEDS-------VPK 471
T N I L+N + I+ ++ Q D+HE+ + +L+++ PK
Sbjct: 349 KDTYNIEIKEMLLLNLKKAISAAAEIFHGNAQNDAHEFLAHCLDQLKDNMEKLNTIWKPK 408
Query: 472 GHKMTESIIYDVFGGLLQQSVKCSNCGEISTTEQPIYDLSLHLKGRKTTDQDQNSVGQDN 531
++ VF +C I+ E + LH K Q +N
Sbjct: 409 SEFGEDNFPKQVFAD--DPDTSGFSCPVITNFELEL----LHSIACKACGQVILKTELNN 462
Query: 532 SIDNSVDQQQSSKRRFSIEKSIRDFFNPELIKRVDNKEGYTCEKCKKVTNALKSNKIIRA 591
+ ++ Q+ + SI+ + FF E ++ Y C KC+ T ++ + R
Sbjct: 463 YLSINLPQRIKA-HPSSIQSTFDLFFGAEELE-------YKCAKCEHKT-SVGVHSFSRL 513
Query: 592 PETLVVHLKKFRFNG-TSSSKMKQAVSYPMFLDLTEYCHESI-SSLPVR-------YQLI 642
P L+VHLK++ N + K Q V +L ++ +C+E LP+ +QL+
Sbjct: 514 PRILIVHLKRYSLNEFCALKKNDQEVIISKYLKVSSHCNEGTRPPLPLSEDGEITDFQLL 573
Query: 643 SVVVHEGRSLSSGH 656
V+ R ++SG+
Sbjct: 574 KVI----RKMTSGN 583
>7293523 [Z] KOG2026 Spindle pole body protein - Sad1p
Length = 719
Score = 55.5 bits (132), Expect = 3e-07
Identities = 79/377 (20%), Positives = 151/377 (39%), Gaps = 56/377 (14%)
Query: 354 SKLTQLKPR---------------GLLNHGVTCYTNAAVQAMVHIPAIQHYLFQLLRGNF 398
SKL QL+P+ GL N Y N + A+ H+ ++ Y Q + ++
Sbjct: 125 SKLDQLQPKHSRTVDGVLYLPGVVGLNNIKANDYCNVVLHALSHVGPLRDYFLQ--KQSY 182
Query: 399 KDTVKSNCVSML-----LAETTMRMWSSDSTKNTYINPDKLINALEDINCMMSAWNQEDS 453
V+ S+ E +MW+ + K+ +++P +++ A+ + ++
Sbjct: 183 AHVVRPPGDSVFTLVQRFGELMRKMWNPRNFKS-HVSPHEMLQAVVLWSSKRFQITEQGD 241
Query: 454 HEYFMSLMSRLQEDSVPKGHKMTESIIYDVFGGLLQQSVKCSNCGEISTTEQPIYDLSLH 513
F+S ++ SI+Y +F G ++ I T + P +L
Sbjct: 242 PIDFLSWFLNTLHRALKGNKHPNSSILYKIFLGEMK----------IYTRKMPPVELDDA 291
Query: 514 LKGRK-TTDQDQNSVGQDNSIDNSVDQQQSSKRRFSIEKSIRDFFNPELIKRVD-----N 567
K + T++ ++ V N I + D D F +I +V+ +
Sbjct: 292 AKAQLLATEEYKDQVEDKNFIYLTCDLPPPPL--------FTDEFRENIIPQVNLYQLLS 343
Query: 568 KEGYTCEKCKKV--TNALKSNKIIRAPETLVVHLKKFRFNGTSSSKMKQAVSYPM----F 621
K T EK K N +K +I R P+ +++++K+F N K V++P+ F
Sbjct: 344 KFNGTAEKEYKTYKANFMKRFEITRLPQFIILYIKRFTKNTFFLEKNPTIVNFPIKHVDF 403
Query: 622 LDLTEYCHESISSLPVRYQLISVVVHEGRSLSSGHYIAH-CKQPDGSWATYDDEYINKIS 680
D+ +Y L++ +VH+G G Y AH + +G W D ++ +I
Sbjct: 404 GDILGMRQRDKDVKDTKYNLVANIVHDG-DPKKGTYRAHILHKANGQWYEMQDLHVTEIL 462
Query: 681 EKQLLKEPNAYFLVYTR 697
Q++ +Y +Y R
Sbjct: 463 -PQMITLTESYIQIYER 478
>At1g04860 [O] KOG1873 Ubiquitin-specific protease
Length = 961
Score = 55.1 bits (131), Expect = 4e-07
Identities = 43/177 (24%), Positives = 76/177 (42%), Gaps = 16/177 (9%)
Query: 362 RGLLNHGVTCYTNAAVQAMVHIPAIQ-HYLFQLLRGNFKDTVKSNCVSMLLAETTMRMWS 420
RGL+N G TC+ N+ +Q ++ + ++ H+L + G+ ++ + L ET
Sbjct: 231 RGLVNLGNTCFFNSIMQNLLSLDRLRDHFLKE--NGSGVGGPLASSLRKLFTET-----K 283
Query: 421 SDSTKNTYINPDKLINALEDINCMMSAWNQEDSHEYFMSLMSRLQEDS--------VPKG 472
++ + INP + ++Q DSHE L+ L + V
Sbjct: 284 PEAGLKSVINPRAFFGSFCSKAPQFRGYDQHDSHELLRCLLDSLSTEESALRKKRGVSDN 343
Query: 473 HKMTESIIYDVFGGLLQQSVKCSNCGEISTTEQPIYDLSLHLKGRKTTDQDQNSVGQ 529
+ + ++I VFGG V C CG S +P DLSL + +K+ + V +
Sbjct: 344 DEKSTTLIESVFGGETSSIVSCMECGHSSKVYEPFLDLSLPVPFKKSPPKKPQPVSR 400
Score = 53.5 bits (127), Expect = 1e-06
Identities = 40/129 (31%), Positives = 64/129 (49%), Gaps = 13/129 (10%)
Query: 581 NALKSNKIIRAPETLVVHLKKFRFNGTSS-SKMKQAVSYPMFLDLTEYCHESISSL-PVR 638
+A K I +AP L +HLK+F + SK+ V++ +DL +Y S P
Sbjct: 831 DATKKVLINKAPPVLTIHLKRFSQDLRGRLSKLNGHVAFKEVIDLRQYMDSRCSGEDPPV 890
Query: 639 YQLISVVVHEGRSLSSGHYIAH------CKQPDGS---WATYDDEYINKISEKQLLKEPN 689
Y+L +V H G ++ GHY+A+ K+ D S W D Y+ ++S +++L
Sbjct: 891 YRLAGLVEHSG-TMRGGHYVAYVRGGQRVKETDSSSTAWYNVSDAYVRQVSLEKVL-HSE 948
Query: 690 AYFLVYTRL 698
AY L Y R+
Sbjct: 949 AYILFYERI 957
>Hs22047539 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 438
Score = 54.7 bits (130), Expect = 5e-07
Identities = 30/93 (32%), Positives = 48/93 (51%), Gaps = 2/93 (2%)
Query: 603 RFNGTSSSKMKQAVSYPMFLDLTEYCHESISSLPVRYQLISVVVHEGRSLSSGHYIAHCK 662
RF+ + +K+ + V YP LD+ Y + + P+ Y L +V+VH G S +GHY ++ K
Sbjct: 190 RFSDVTGNKIAKNVQYPECLDMQPYMSQQNTG-PLVYVLYAVLVHAGWSCHNGHYFSYVK 248
Query: 663 QPDGSWATYDDEYINKISEKQLLKEPNAYFLVY 695
+G W DD + +L + AY L Y
Sbjct: 249 VQEGQWYKMDDAEVTASGITSVLSQ-QAYVLFY 280
>7292313 [O] KOG0944 Ubiquitin-specific protease UBP14
Length = 827
Score = 52.8 bits (125), Expect = 2e-06
Identities = 60/290 (20%), Positives = 115/290 (38%), Gaps = 43/290 (14%)
Query: 363 GLLNHGVTCYTNAAVQAMVHIPAIQHYL-------------------FQLLRGNFKDTVK 403
G+ N G +CY N+ +Q + IP Q F + ++
Sbjct: 333 GMRNLGNSCYINSVMQVLFVIPDFQQRFVGTGAERYFKEFPSDPANDFNIQMAKLGTGLQ 392
Query: 404 SNCVSMLLAETTMRMWSSDSTKNTYINPDKLINALEDINCMMSAWNQEDSHEYFMSLMSR 463
S S + AE T+ D+ +T I+P N + + S Q+D++++++ L++
Sbjct: 393 SGKYSSI-AENTL-----DTDHSTGISPAMFKNIVGKNHPDFSTKQQQDANDFYLHLLTL 446
Query: 464 LQEDSVPKGHKMTESIIYDVFGGLLQQSVKCSNCGEISTTEQPIYDLSLHLKGRKTTDQD 523
L +S ++ D LL+ V+C ++ + Y L + K T+ D
Sbjct: 447 LDRNS------RNQTNPADALKFLLEDRVECLASHKVKYNTREEYSFRLPVPLDKATNLD 500
Query: 524 QNSVGQDNS-----IDNSVDQQQSSKRRFSIEKSIRDFFNPELIKRVDNKEGYTCEKCKK 578
+ Q+ + + + + ++ + FF PELI E +
Sbjct: 501 EVREFQERKKAARETGQRLPDRDIVRHKVPLQACLERFFGPELI------EQFYSTAIGS 554
Query: 579 VTNALKSNKIIRAPETLVVHLKKFRF-NGTSSSKMKQAVSYPMFLDLTEY 627
TNA K ++ P+ L++H+ KF + K+ +V P LDL+ +
Sbjct: 555 KTNARKITRLATMPDCLMIHVGKFTLGDDWVPKKLDVSVDMPDELDLSNW 604
>Hs20483065 [O] KOG1864 Ubiquitin-specific protease
Length = 749
Score = 50.8 bits (120), Expect = 7e-06
Identities = 50/219 (22%), Positives = 93/219 (41%), Gaps = 36/219 (16%)
Query: 521 DQDQNSVGQDNSIDNSVDQQQ---SSKRRFSIEKSIRDFFNPELIKRVDNKEGYTCEKCK 577
+++++S+G D ++ + S+ S+ + F +PE ++ + Y CE C
Sbjct: 461 EKEEDSLGAGTHPDAAIPSGERTCGSEGSRSVLDLVNYFLSPE---KLTAENRYYCESCA 517
Query: 578 KVTNALKSNKIIRAPETLVVHLKKFRFNGTSSSKMK--QAVSYPMFLDLTEYCHESISSL 635
+ +A K ++ + P L++ L +F F+ + + K VS P+ L L
Sbjct: 518 SLQDAEKVVELSQGPCYLILTLLRFSFDLRTMRRRKILDDVSIPLLLRLP-----LAGGR 572
Query: 636 PVRYQLISVVVHEGRSLSSGHYIAHCK----------------QPDGSWATYDDEYINKI 679
Y L SVVVH G S SGHY + + +P+ W ++D ++
Sbjct: 573 GQAYDLCSVVVHSGVSSESGHYYCYAREGAARPAASLGTADRPEPENQWYLFNDTRVSFS 632
Query: 680 SEKQL------LKEPNAYFLVYTRLTPKSVPLSSQSSNK 712
S + + + AY L Y R P+ P + S++
Sbjct: 633 SFESVSNVTSFFPKDTAYVLFY-RQRPREGPEAELGSSR 670
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.312 0.128 0.361
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 35,232,495
Number of Sequences: 60738
Number of extensions: 1386992
Number of successful extensions: 4706
Number of sequences better than 1.0e-05: 120
Number of HSP's better than 0.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 112
Number of HSP's that attempted gapping in prelim test: 4271
Number of HSP's gapped (non-prelim): 243
length of query: 750
length of database: 30,389,216
effective HSP length: 114
effective length of query: 636
effective length of database: 23,465,084
effective search space: 14923793424
effective search space used: 14923793424
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)