ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIV2129 good OT KOG1554 Posttranslational modification, protein turnover, chaperones COP9 signalosome, subunit CSN5
r_klactIV2129 good OT KOG1554 Signal transduction mechanisms COP9 signalosome, subunit CSN5
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIV2129 725605 726723 373
(373 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YDL216c [OT] KOG1554 COP9 signalosome subunit CSN5 192 5e-49
At1g22920 [OT] KOG1554 COP9 signalosome subunit CSN5 179 4e-45
At1g71230 [OT] KOG1554 COP9 signalosome subunit CSN5 170 3e-42
7300154 [OT] KOG1554 COP9 signalosome subunit CSN5 169 6e-42
CE06722 [OT] KOG1554 COP9 signalosome subunit CSN5 167 2e-41
Hs5803046 [OT] KOG1554 COP9 signalosome subunit CSN5 164 1e-40
SPAC1687.13c [OT] KOG1554 COP9 signalosome subunit CSN5 157 2e-38
Hs17463759 [OT] KOG1554 COP9 signalosome subunit CSN5 127 2e-29
CE00707 [O] KOG1555 26S proteasome regulatory complex subunit RPN11 102 7e-22
CE19527 [O] KOG1555 26S proteasome regulatory complex subunit RPN11 98 2e-20
YFR004w [O] KOG1555 26S proteasome regulatory complex subunit RPN11 96 7e-20
SPAC31G5.13 [O] KOG1555 26S proteasome regulatory complex subuni... 96 1e-19
Hs5031981 [O] KOG1555 26S proteasome regulatory complex subunit ... 95 2e-19
7296942 [O] KOG1555 26S proteasome regulatory complex subunit RPN11 94 2e-19
ECU11g0570 [O] KOG1555 26S proteasome regulatory complex subunit... 94 3e-19
At5g23540 [O] KOG1555 26S proteasome regulatory complex subunit ... 94 4e-19
7301945 [T] KOG2880 SMAD6 interacting protein AMSH contains JAB/... 50 5e-06
>YDL216c [OT] KOG1554 COP9 signalosome subunit CSN5
Length = 455
Score = 192 bits (489), Expect = 5e-49
Identities = 103/232 (44%), Positives = 144/232 (61%), Gaps = 17/232 (7%)
Query: 67 LISRLATTKMLSHAVDGGDIEVMGMLVGYTSNDMIVVKDCYSLPVQGTETRVNAHMESYE 126
LIS+L+ K+ +AV GG+IE+MG+L+G+T D IVV DC++LPV GTETRVNA +ESYE
Sbjct: 87 LISKLSCEKITHYAVRGGNIEIMGILMGFTLKDNIVVMDCFNLPVVGTETRVNAQLESYE 146
Query: 127 YMVQYLDAFVTKED------------KIVGWYHSHPGYGCWLSNIDIQTQSLNQNYQDPY 174
YMVQY+D D +VGW+HSHPGY CWLSNIDIQTQ LNQ +QDPY
Sbjct: 147 YMVQYIDEMYNHNDGGDGRDYKGAKLNVVGWFHSHPGYDCWLSNIDIQTQDLNQRFQDPY 206
Query: 175 LAIVVDPKKSLSGNTLDIGAFRTLPSK-DNNEHVDYYPLNIQLYQNSLDVNISKLKLKFK 233
+AIVVDP KSL L +GAFRT+ SK D+N YY L ++ + L N + + K
Sbjct: 207 VAIVVDPLKSLEDKILRMGAFRTIESKSDDNSATSYYELETIIFDSEL--NRALFETKLN 264
Query: 234 VDPAIQNNPNEPELMKELHECVENWFHA--KKVMKSTVGFNAIGSTVVNETE 283
+ I+++ +E + L + ++ + + K +++ + V NE +
Sbjct: 265 LHCVIEDDESEQISLNRLIDSMKQYSYLMDSKNVRTRIKLATTSERVSNENK 316
>At1g22920 [OT] KOG1554 COP9 signalosome subunit CSN5
Length = 357
Score = 179 bits (455), Expect = 4e-45
Identities = 91/201 (45%), Positives = 129/201 (63%), Gaps = 27/201 (13%)
Query: 51 PYATDLKRNPCHFQKCLISRLATTKMLSHAVDGGDIEVMGMLVGYTSNDMIVVKDCYSLP 110
P+A+D P +F++ IS LA KM+ HA GG IE+MG++ G T D I+V D ++LP
Sbjct: 48 PWASD----PNYFKRVHISALALLKMVVHARSGGTIEIMGLMQGKTEGDTIIVMDAFALP 103
Query: 111 VQGTETRVNAHMESYEYMVQYLDA--FVTKEDKIVGWYHSHPGYGCWLSNIDIQTQSLNQ 168
V+GTETRVNA ++YEYMV+Y + + +VGWYHSHPGYGCWLS ID+ TQ LNQ
Sbjct: 104 VEGTETRVNAQSDAYEYMVEYSQTSKLAGRLENVVGWYHSHPGYGCWLSGIDVSTQMLNQ 163
Query: 169 NYQDPYLAIVVDPKKSLSGNTLDIGAFRTLPS--KDNNEHV------------------- 207
YQ+P+LA+V+DP +++S ++IGAFRT P K +++HV
Sbjct: 164 QYQEPFLAVVIDPTRTVSAGKVEIGAFRTYPEGHKISDDHVSEYQTIPLNKIEDFGVHCK 223
Query: 208 DYYPLNIQLYQNSLDVNISKL 228
YY L+I +++SLD ++ L
Sbjct: 224 QYYSLDITYFKSSLDSHLLDL 244
>At1g71230 [OT] KOG1554 COP9 signalosome subunit CSN5
Length = 358
Score = 170 bits (431), Expect = 3e-42
Identities = 84/195 (43%), Positives = 125/195 (64%), Gaps = 23/195 (11%)
Query: 57 KRNPCHFQKCLISRLATTKMLSHAVDGGDIEVMGMLVGYTSNDMIVVKDCYSLPVQGTET 116
+ +P +F++ IS LA KM+ HA GG IE+MG++ G T D I+V D ++LPV+GTET
Sbjct: 50 ENDPHYFKRVKISALALLKMVVHARSGGTIEIMGLMQGKTDGDTIIVMDAFALPVEGTET 109
Query: 117 RVNAHMESYEYMVQY--LDAFVTKEDKIVGWYHSHPGYGCWLSNIDIQTQSLNQNYQDPY 174
RVNA ++YEYMV+Y + + + +VGWYHSHPGYGCWLS ID+ TQ LNQ +Q+P+
Sbjct: 110 RVNAQDDAYEYMVEYSQTNKLAGRLENVVGWYHSHPGYGCWLSGIDVSTQRLNQQHQEPF 169
Query: 175 LAIVVDPKKSLSGNTLDIGAFRTL------PSKDNNEH---------------VDYYPLN 213
LA+V+DP +++S ++IGAFRT P + +E+ YY L+
Sbjct: 170 LAVVIDPTRTVSAGKVEIGAFRTYSKGYKPPDEPVSEYQTIPLNKIEDFGVHCKQYYSLD 229
Query: 214 IQLYQNSLDVNISKL 228
+ +++SLD ++ L
Sbjct: 230 VTYFKSSLDSHLLDL 244
>7300154 [OT] KOG1554 COP9 signalosome subunit CSN5
Length = 327
Score = 169 bits (428), Expect = 6e-42
Identities = 85/189 (44%), Positives = 120/189 (62%), Gaps = 23/189 (12%)
Query: 57 KRNPCHFQKCLISRLATTKMLSHAVDGGDIEVMGMLVGYTSNDMIVVKDCYSLPVQGTET 116
+++P F+ IS LA KM+ HA GG +EVMG+++G ++ ++V D ++LPV+GTET
Sbjct: 43 EKDPHFFKDIKISALALLKMVMHARSGGTLEVMGLMLGKVEDNTMIVMDAFALPVEGTET 102
Query: 117 RVNAHMESYEYMVQYLDAF--VTKEDKIVGWYHSHPGYGCWLSNIDIQTQSLNQNYQDPY 174
RVNA ++YEYM Y++A V + + VGWYHSHPGYGCWLS ID+ TQ LNQ YQ+P+
Sbjct: 103 RVNAQAQAYEYMTAYMEAAKEVGRMEHAVGWYHSHPGYGCWLSGIDVSTQMLNQTYQEPF 162
Query: 175 LAIVVDPKKSLSGNTLDIGAFRTLPS--KDNNEH-------------------VDYYPLN 213
+AIVVDP +++S + +GAFRT P K NE YYPL
Sbjct: 163 VAIVVDPVRTVSAGKVCLGAFRTYPKGYKPPNEEPSEYQTIPLNKIEDFGVHCKQYYPLE 222
Query: 214 IQLYQNSLD 222
I ++++LD
Sbjct: 223 ISYFKSALD 231
>CE06722 [OT] KOG1554 COP9 signalosome subunit CSN5
Length = 368
Score = 167 bits (424), Expect = 2e-41
Identities = 81/191 (42%), Positives = 122/191 (63%), Gaps = 23/191 (12%)
Query: 58 RNPCHFQKCLISRLATTKMLSHAVDGGDIEVMGMLVGYTSNDMIVVKDCYSLPVQGTETR 117
++P +F++ IS +A KM HA GG++E+MG+L G + ++ D ++LPV+GTETR
Sbjct: 48 KDPHYFKQIKISAIALLKMTMHAKRGGNLEIMGLLQGRIDANSFIILDVFALPVEGTETR 107
Query: 118 VNAHMESYEYMVQYLDAFVT--KEDKIVGWYHSHPGYGCWLSNIDIQTQSLNQNYQDPYL 175
VNA ++YEYM Y + T +++K+VGWYHSHPGYGCWLS ID+ TQ+LNQ +Q+P++
Sbjct: 108 VNAQAQAYEYMTVYSEMCDTEGRKEKVVGWYHSHPGYGCWLSGIDVSTQTLNQKFQEPWV 167
Query: 176 AIVVDPKKSLSGNTLDIGAFRTLPS--------------------KDNNEHVD-YYPLNI 214
AIV+DP +++S +DIGAFRT P +D H YY L++
Sbjct: 168 AIVIDPLRTMSAGKVDIGAFRTYPEGYRPPDDVPSEYQSIPLAKIEDFGVHCKRYYSLDV 227
Query: 215 QLYQNSLDVNI 225
+++ LD +I
Sbjct: 228 SFFKSQLDAHI 238
>Hs5803046 [OT] KOG1554 COP9 signalosome subunit CSN5
Length = 334
Score = 164 bits (416), Expect = 1e-40
Identities = 78/190 (41%), Positives = 119/190 (62%), Gaps = 23/190 (12%)
Query: 62 HFQKCLISRLATTKMLSHAVDGGDIEVMGMLVGYTSNDMIVVKDCYSLPVQGTETRVNAH 121
+F+ C IS LA KM+ HA GG++EVMG+++G + +++ D ++LPV+GTETRVNA
Sbjct: 51 YFKYCKISALALLKMVMHARSGGNLEVMGLMLGKVDGETMIIMDSFALPVEGTETRVNAQ 110
Query: 122 MESYEYMVQYLDAF--VTKEDKIVGWYHSHPGYGCWLSNIDIQTQSLNQNYQDPYLAIVV 179
+YEYM Y++ V + + +GWYHSHPGYGCWLS ID+ TQ LNQ +Q+P++A+V+
Sbjct: 111 AAAYEYMAAYIENAKQVGRLENAIGWYHSHPGYGCWLSGIDVSTQMLNQQFQEPFVAVVI 170
Query: 180 DPKKSLSGNTLDIGAFRTLPS--------------------KDNNEHV-DYYPLNIQLYQ 218
DP +++S +++GAFRT P +D H YY L + ++
Sbjct: 171 DPTRTISAGKVNLGAFRTYPKGYKPPDEGPSEYQTIPLNKIEDFGVHCKQYYALEVSYFK 230
Query: 219 NSLDVNISKL 228
+SLD + +L
Sbjct: 231 SSLDRKLLEL 240
>SPAC1687.13c [OT] KOG1554 COP9 signalosome subunit CSN5
Length = 299
Score = 157 bits (398), Expect = 2e-38
Identities = 73/145 (50%), Positives = 99/145 (67%), Gaps = 2/145 (1%)
Query: 57 KRNPCHFQKCLISRLATTKMLSHAVDGGDIEVMGMLVGYTSNDMIVVKDCYSLPVQGTET 116
K +P F+ IS +A KML H G +EVMG + G +++ D ++LPV+GTET
Sbjct: 26 KHDPEFFRSVKISAVALLKMLRHVSQGMPLEVMGYVQGKVEGASLIILDSFALPVEGTET 85
Query: 117 RVNAHMESYEYMVQY--LDAFVTKEDKIVGWYHSHPGYGCWLSNIDIQTQSLNQNYQDPY 174
RVNAH E+ EY VQY L V + + ++GWYHSHP YGCWLS +D++TQ NQ YQDP+
Sbjct: 86 RVNAHEEAQEYSVQYHTLCKSVYRHENVIGWYHSHPNYGCWLSGVDVETQRQNQKYQDPF 145
Query: 175 LAIVVDPKKSLSGNTLDIGAFRTLP 199
+A+V+DPK+SL ++IGAFRT P
Sbjct: 146 VAVVLDPKRSLESPYVNIGAFRTYP 170
>Hs17463759 [OT] KOG1554 COP9 signalosome subunit CSN5
Length = 254
Score = 127 bits (320), Expect = 2e-29
Identities = 59/136 (43%), Positives = 89/136 (65%), Gaps = 4/136 (2%)
Query: 66 CLISRLATTKMLSHAVDGGDIEVMGMLVGYTSNDMIVVKDCYSLPVQGTETRVNAHMESY 125
C IS LA KM+ HA GG++EVMG++ G + ++ ++LPV+GTETR NA +Y
Sbjct: 19 CKISALALLKMMMHARSGGNLEVMGLMPGKVDGETTIIMGSFTLPVEGTETRENAEAVAY 78
Query: 126 EYMVQYLD--AFVTKEDKIVGWYHSHPGYGCWLSNIDIQTQSLNQNYQDPYLAIVVDPKK 183
EYM Y + V + +GWY+ HPG+GCWLS I TQ LN+ +++P+ A+V+DP +
Sbjct: 79 EYMATYTENAKKVGRLKNAIGWYYRHPGHGCWLSG--IITQLLNKRFREPFTAVVIDPTR 136
Query: 184 SLSGNTLDIGAFRTLP 199
++S +++ AFRT P
Sbjct: 137 TISAGKVNLDAFRTYP 152
>CE00707 [O] KOG1555 26S proteasome regulatory complex subunit RPN11
Length = 319
Score = 102 bits (255), Expect = 7e-22
Identities = 60/165 (36%), Positives = 91/165 (54%), Gaps = 13/165 (7%)
Query: 53 ATDLKRNPCHFQKCLISRLATTKMLSHAVDGGDIEVMGMLVGYTSNDMIV-VKDCYSLPV 111
ATD +P + IS LA KML HA G +EVMG+++G +D + V D +++P
Sbjct: 16 ATDKLDHPDTSETVNISSLALLKMLRHARSGIPLEVMGLMLGDFVDDYTINVTDVFAMPQ 75
Query: 112 QGTETRVNAHMESYEYMVQYLDAFVTKEDKIVGWYHSHPGYGCWLSNIDIQTQSLNQNYQ 171
GT V + Y+ L V + + +VGWYHSHPG+GCWLS++D+ TQ +
Sbjct: 76 SGTSVTVESVDPVYQTKHMDLLKLVGRTENVVGWYHSHPGFGCWLSSVDVNTQQSFEALH 135
Query: 172 DPYLAIVVDPKKSLSGNTLDIGAFRTLPSKDNNEHVDYYPLNIQL 216
+A+VVDP +S+ G + + AFR++ PLN+Q+
Sbjct: 136 PRAVAVVVDPIQSVKGKVM-LDAFRSV-----------NPLNLQI 168
>CE19527 [O] KOG1555 26S proteasome regulatory complex subunit RPN11
Length = 312
Score = 98.2 bits (243), Expect = 2e-20
Identities = 54/132 (40%), Positives = 78/132 (58%), Gaps = 2/132 (1%)
Query: 68 ISRLATTKMLSHAVDGGDIEVMGMLVGYTSNDMIV-VKDCYSLPVQGTETRVNAHMESYE 126
IS LA KML H G +EVMG+++G +D V V D +++P GT V A ++
Sbjct: 35 ISSLALLKMLKHGRAGVPMEVMGLMLGEFVDDYTVNVIDVFAMPQSGTGVSVEAVDPVFQ 94
Query: 127 YMVQYLDAFVTKEDKIVGWYHSHPGYGCWLSNIDIQTQSLNQNYQDPYLAIVVDPKKSLS 186
+ + + + +VGWYHSHPG+GCWLS +DI TQ + D +A+VVDP +S+
Sbjct: 95 AKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDINTQQSFEALSDRAVAVVVDPIQSVK 154
Query: 187 GNTLDIGAFRTL 198
G + I AFRT+
Sbjct: 155 GKVV-IDAFRTI 165
>YFR004w [O] KOG1555 26S proteasome regulatory complex subunit RPN11
Length = 306
Score = 96.3 bits (238), Expect = 7e-20
Identities = 50/132 (37%), Positives = 78/132 (58%), Gaps = 2/132 (1%)
Query: 68 ISRLATTKMLSHAVDGGDIEVMGMLVGYTSNDMIV-VKDCYSLPVQGTETRVNAHMESYE 126
IS +A KML H G +EVMG+++G +D V V D +++P GT V A + ++
Sbjct: 29 ISSIALLKMLKHGRAGVPMEVMGLMLGEFVDDYTVNVVDVFAMPQSGTGVSVEAVDDVFQ 88
Query: 127 YMVQYLDAFVTKEDKIVGWYHSHPGYGCWLSNIDIQTQSLNQNYQDPYLAIVVDPKKSLS 186
+ + ++ +VGWYHSHPG+GCWLS++D+ TQ + +A+VVDP +S+
Sbjct: 89 AKMMDMLKQTGRDQMVVGWYHSHPGFGCWLSSVDVNTQKSFEQLNSRAVAVVVDPIQSVK 148
Query: 187 GNTLDIGAFRTL 198
G + I AFR +
Sbjct: 149 GKVV-IDAFRLI 159
>SPAC31G5.13 [O] KOG1555 26S proteasome regulatory complex subunit RPN11
Length = 308
Score = 95.5 bits (236), Expect = 1e-19
Identities = 52/132 (39%), Positives = 77/132 (57%), Gaps = 2/132 (1%)
Query: 68 ISRLATTKMLSHAVDGGDIEVMGMLVGYTSNDMIV-VKDCYSLPVQGTETRVNAHMESYE 126
IS LA KML H G +EVMG+++G +D V V D +++P GT V A ++
Sbjct: 32 ISSLALLKMLRHGRHGTPMEVMGLMLGEFVDDFTVRVVDVFAMPQSGTGVSVEAVDPVFQ 91
Query: 127 YMVQYLDAFVTKEDKIVGWYHSHPGYGCWLSNIDIQTQSLNQNYQDPYLAIVVDPKKSLS 186
+ + + + +VGWYHSHPG+GCWLS++DI TQ + +A+VVDP +S+
Sbjct: 92 KNMMDMLKQTGRPEMVVGWYHSHPGFGCWLSSVDINTQQSFEQLTPRAVAVVVDPIQSVK 151
Query: 187 GNTLDIGAFRTL 198
G + I AFR +
Sbjct: 152 GKVV-IDAFRLI 162
>Hs5031981 [O] KOG1555 26S proteasome regulatory complex subunit RPN11
Length = 310
Score = 94.7 bits (234), Expect = 2e-19
Identities = 52/136 (38%), Positives = 79/136 (57%), Gaps = 2/136 (1%)
Query: 64 QKCLISRLATTKMLSHAVDGGDIEVMGMLVGYTSNDMIV-VKDCYSLPVQGTETRVNAHM 122
++ IS LA KML H G +EVMG+++G +D V V D +++P GT V A
Sbjct: 29 EQVYISSLALLKMLKHGRAGVPMEVMGLMLGEFVDDYTVRVIDVFAMPQSGTGVSVEAVD 88
Query: 123 ESYEYMVQYLDAFVTKEDKIVGWYHSHPGYGCWLSNIDIQTQSLNQNYQDPYLAIVVDPK 182
++ + + + + +VGWYHSHPG+GCWLS +DI TQ + + +A+VVDP
Sbjct: 89 PVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDINTQQSFEALSERAVAVVVDPI 148
Query: 183 KSLSGNTLDIGAFRTL 198
+S+ G + I AFR +
Sbjct: 149 QSVKGKVV-IDAFRLI 163
>7296942 [O] KOG1555 26S proteasome regulatory complex subunit RPN11
Length = 308
Score = 94.4 bits (233), Expect = 2e-19
Identities = 52/136 (38%), Positives = 79/136 (57%), Gaps = 2/136 (1%)
Query: 64 QKCLISRLATTKMLSHAVDGGDIEVMGMLVGYTSNDMIV-VKDCYSLPVQGTETRVNAHM 122
++ IS LA KML H G +EVMG+++G +D V V D +++P GT V A
Sbjct: 27 EQVYISSLALLKMLKHGRAGVPMEVMGLMLGEFVDDYTVQVIDVFAMPQTGTGVSVEAVD 86
Query: 123 ESYEYMVQYLDAFVTKEDKIVGWYHSHPGYGCWLSNIDIQTQSLNQNYQDPYLAIVVDPK 182
++ + + + + +VGWYHSHPG+GCWLS +DI TQ + + +A+VVDP
Sbjct: 87 PVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDINTQQSFEALSERAVAVVVDPI 146
Query: 183 KSLSGNTLDIGAFRTL 198
+S+ G + I AFR +
Sbjct: 147 QSVKGKVV-IDAFRLI 161
>ECU11g0570 [O] KOG1555 26S proteasome regulatory complex subunit RPN11
Length = 294
Score = 94.0 bits (232), Expect = 3e-19
Identities = 49/135 (36%), Positives = 77/135 (56%), Gaps = 2/135 (1%)
Query: 68 ISRLATTKMLSHAVDGGDIEVMGMLVG-YTSNDMIVVKDCYSLPVQGTETRVNAHMESYE 126
IS LA KML H G +EVMG+++G + + V D +++P GT V + ++
Sbjct: 23 ISSLALLKMLKHGRAGIPLEVMGLMLGEFVDEYTVKVVDVFAMPQSGTNVTVESVDPIFQ 82
Query: 127 YMVQYLDAFVTKEDKIVGWYHSHPGYGCWLSNIDIQTQSLNQNYQDPYLAIVVDPKKSLS 186
+ + + + +VGWYHSHPG+GCWLS +DI TQ + +A+VVDP +S+
Sbjct: 83 MEMMSILKATGRHETVVGWYHSHPGFGCWLSTVDISTQQSFEKLCKRAVAVVVDPIQSVK 142
Query: 187 GNTLDIGAFRTLPSK 201
G + I AFR + ++
Sbjct: 143 GKVV-IDAFRLIDNQ 156
>At5g23540 [O] KOG1555 26S proteasome regulatory complex subunit RPN11
Length = 308
Score = 93.6 bits (231), Expect = 4e-19
Identities = 51/136 (37%), Positives = 79/136 (57%), Gaps = 2/136 (1%)
Query: 64 QKCLISRLATTKMLSHAVDGGDIEVMGMLVGYTSNDMIV-VKDCYSLPVQGTETRVNAHM 122
++ IS LA KML H G +EVMG+++G ++ V V D +++P GT V A
Sbjct: 28 EQVYISSLALLKMLKHGRAGVPMEVMGLMLGEFVDEYTVRVVDVFAMPQSGTGVSVEAVD 87
Query: 123 ESYEYMVQYLDAFVTKEDKIVGWYHSHPGYGCWLSNIDIQTQSLNQNYQDPYLAIVVDPK 182
++ + + + + +VGWYHSHPG+GCWLS +DI TQ + +A+VVDP
Sbjct: 88 HVFQTNMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDINTQQSFEALNQRAVAVVVDPI 147
Query: 183 KSLSGNTLDIGAFRTL 198
+S+ G + I AFR++
Sbjct: 148 QSVKGKVV-IDAFRSI 162
>7301945 [T] KOG2880 SMAD6 interacting protein AMSH contains JAB/MPN/Mov34
domain
Length = 420
Score = 50.1 bits (118), Expect = 5e-06
Identities = 31/103 (30%), Positives = 48/103 (46%), Gaps = 5/103 (4%)
Query: 85 DIEVMGMLVGYTSNDMIVVKDCYSLPVQGTETRVNAHMESYEYMVQYLDAFVTKEDKIVG 144
+IE G+L G+ S + + + + QGT N E + VQ +T +G
Sbjct: 271 NIETCGVLAGHLSQNQLYITHIITPQQQGTPDSCNTMHEEQIFDVQDQMQLIT-----LG 325
Query: 145 WYHSHPGYGCWLSNIDIQTQSLNQNYQDPYLAIVVDPKKSLSG 187
W H+HP +LS++D+ T Q LAIV PK + +G
Sbjct: 326 WIHTHPTQTAFLSSVDLHTHCSYQIMMPEALAIVCAPKYNTTG 368
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.316 0.133 0.394
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,470,432
Number of Sequences: 60738
Number of extensions: 763939
Number of successful extensions: 1796
Number of sequences better than 1.0e-05: 17
Number of HSP's better than 0.0 without gapping: 16
Number of HSP's successfully gapped in prelim test: 1
Number of HSP's that attempted gapping in prelim test: 1760
Number of HSP's gapped (non-prelim): 18
length of query: 373
length of database: 30,389,216
effective HSP length: 108
effective length of query: 265
effective length of database: 23,829,512
effective search space: 6314820680
effective search space used: 6314820680
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)