ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIV2150 good U KOG0166 Intracellular trafficking, secretion, and vesicular transport Karyopherin (importin) alpha
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIV2150 731805 730192 -538
(538 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YNL189w [U] KOG0166 Karyopherin (importin) alpha 883 0.0
SPCC962.03c [U] KOG0166 Karyopherin (importin) alpha 607 e-173
SPBC1604.08c [U] KOG0166 Karyopherin (importin) alpha 599 e-171
Hs6912478 [U] KOG0166 Karyopherin (importin) alpha 522 e-148
Hs22043735 [U] KOG0166 Karyopherin (importin) alpha 514 e-146
Hs4504903 [U] KOG0166 Karyopherin (importin) alpha 513 e-145
Hs4504895 [U] KOG0166 Karyopherin (importin) alpha 511 e-145
At1g09270 [U] KOG0166 Karyopherin (importin) alpha 493 e-139
At3g06720 [U] KOG0166 Karyopherin (importin) alpha 484 e-136
At1g02690 [U] KOG0166 Karyopherin (importin) alpha 483 e-136
At4g02150 [U] KOG0166 Karyopherin (importin) alpha 478 e-134
7293740 [U] KOG0166 Karyopherin (importin) alpha 450 e-126
At5g49310 [U] KOG0166 Karyopherin (importin) alpha 438 e-122
Hs4504901 [U] KOG0166 Karyopherin (importin) alpha 433 e-121
Hs4504897 [U] KOG0166 Karyopherin (importin) alpha 425 e-118
Hs4504899 [U] KOG0166 Karyopherin (importin) alpha 420 e-117
CE20745 [U] KOG0166 Karyopherin (importin) alpha 405 e-112
7299211 [U] KOG0166 Karyopherin (importin) alpha 401 e-111
At3g05720 [U] KOG0166 Karyopherin (importin) alpha 386 e-107
7297600 [U] KOG0166 Karyopherin (importin) alpha 373 e-103
At5g52000 [U] KOG0166 Karyopherin (importin) alpha 329 6e-90
CE09675 [U] KOG0166 Karyopherin (importin) alpha 290 3e-78
ECU11g1760 [U] KOG0166 Karyopherin (importin) alpha 251 1e-66
At5g03070 [U] KOG0166 Karyopherin (importin) alpha 187 3e-47
7295403 [U] KOG0166 Karyopherin (importin) alpha 178 2e-44
Hs17443779 [U] KOG0166 Karyopherin (importin) alpha 166 6e-41
Hs17464994 [U] KOG0166 Karyopherin (importin) alpha 154 3e-37
Hs22051967_1 [U] KOG0166 Karyopherin (importin) alpha 132 2e-30
Hs20538368 [U] KOG0166 Karyopherin (importin) alpha 128 2e-29
At1g32880 [U] KOG0166 Karyopherin (importin) alpha 119 2e-26
Hs17469107 [U] KOG0166 Karyopherin (importin) alpha 101 2e-21
CE06461 [U] KOG0166 Karyopherin (importin) alpha 97 8e-20
CE28029 [U] KOG0166 Karyopherin (importin) alpha 91 3e-18
Hs6912678 [U] KOG0166 Karyopherin (importin) alpha 89 2e-17
Hs18562577 [U] KOG0166 Karyopherin (importin) alpha 88 4e-17
YEL013w [U] KOG4224 Armadillo repeat protein VAC8 required for v... 83 9e-16
SPBC354.14c [U] KOG4224 Armadillo repeat protein VAC8 required f... 72 3e-12
At5g19330 [S] KOG0167 FOG: Armadillo/beta-catenin-like repeats 71 5e-12
At5g13060 [S] KOG0167 FOG: Armadillo/beta-catenin-like repeats 70 8e-12
Hs10863903_1 [O] KOG0168 Putative ubiquitin fusion degradation p... 64 6e-10
At4g38610 [O] KOG0168 Putative ubiquitin fusion degradation protein 57 7e-08
At1g77460 [S] KOG0167 FOG: Armadillo/beta-catenin-like repeats 55 2e-07
At1g23180 [S] KOG0167 FOG: Armadillo/beta-catenin-like repeats 55 3e-07
At1g23030 [S] KOG0167 FOG: Armadillo/beta-catenin-like repeats 55 3e-07
At4g12710 [S] KOG0167 FOG: Armadillo/beta-catenin-like repeats 54 6e-07
At1g01830 [S] KOG0167 FOG: Armadillo/beta-catenin-like repeats 52 3e-06
>YNL189w [U] KOG0166 Karyopherin (importin) alpha
Length = 542
Score = 883 bits (2282), Expect = 0.0
Identities = 441/535 (82%), Positives = 478/535 (88%), Gaps = 1/535 (0%)
Query: 5 TSSKFVPEYRRTNFKNKGRFSADELRRRRDVQQVELRKVKRDEALAKRRNFNAPV-GNXX 63
++SKFVPEYRRTNFKNKGRFSADELRRRRD QQVELRK KRDEALAKRRNF P G
Sbjct: 8 STSKFVPEYRRTNFKNKGRFSADELRRRRDTQQVELRKAKRDEALAKRRNFIPPTDGADS 67
Query: 64 XXXXXXXXXXXXXFYRQLQQELPAMLEQIHSNDLQQQLAVTVKFRQVLSREHRPPIDLVI 123
FY QLQQELP M +Q++S+D+Q+QL+ TVKFRQ+LSREHRPPID+VI
Sbjct: 68 DEEDESSVSADQQFYSQLQQELPQMTQQLNSDDMQEQLSATVKFRQILSREHRPPIDVVI 127
Query: 124 STGVVPTLVQFMSENQPEMLQLEAAWALTNIASGTSEQTRVVVDAGAVPLFIQLLYSNSV 183
GVVP LV+FM ENQPEMLQLEAAWALTNIASGTS QT+VVVDA AVPLFIQLLY+ SV
Sbjct: 128 QAGVVPRLVEFMRENQPEMLQLEAAWALTNIASGTSAQTKVVVDADAVPLFIQLLYTGSV 187
Query: 184 EVKEQAIWALGNVAGDSTDYRDYVLQCGAMQPILYLFELNKTSLIRTATWTLSNLCRGKK 243
EVKEQAIWALGNVAGDSTDYRDYVLQC AM+PIL LF NK SLIRTATWTLSNLCRGKK
Sbjct: 188 EVKEQAIWALGNVAGDSTDYRDYVLQCNAMEPILGLFNSNKPSLIRTATWTLSNLCRGKK 247
Query: 244 PQPDWSIVSQALPTLSKLIYSMDTETLVDACWAISYLSDGPVNSIQAVVDARIPKRLVEL 303
PQPDWS+VSQALPTL+KLIYSMDTETLVDACWAISYLSDGP +IQAV+D RIPKRLVEL
Sbjct: 248 PQPDWSVVSQALPTLAKLIYSMDTETLVDACWAISYLSDGPQEAIQAVIDVRIPKRLVEL 307
Query: 304 LSHQSTLVQTPALRAVGNIVTGNDLQTQIVINCGALAALRNLLASPKESIRKEACWTISN 363
LSH+STLVQTPALRAVGNIVTGNDLQTQ+VIN G L ALR LL+SPKE+I+KEACWTISN
Sbjct: 308 LSHESTLVQTPALRAVGNIVTGNDLQTQVVINAGVLPALRLLLSSPKENIKKEACWTISN 367
Query: 364 ITAGNTEQIQAVIDANLIPPLIRLLETAEYKTKKEACWAISNASSGGLHKPEIIRYLVSQ 423
ITAGNTEQIQAVIDANLIPPL++LLE AEYKTKKEACWAISNASSGGL +P+IIRYLVSQ
Sbjct: 368 ITAGNTEQIQAVIDANLIPPLVKLLEVAEYKTKKEACWAISNASSGGLQRPDIIRYLVSQ 427
Query: 424 GCIKPLCDLLEIADNRIIEVTLDAIENILKMGEMDREVRGIAVNENADFIEKAGGMEKIF 483
GCIKPLCDLLEIADNRIIEVTLDA+ENILKMGE D+E RG+ +NENADFIEKAGGMEKIF
Sbjct: 428 GCIKPLCDLLEIADNRIIEVTLDALENILKMGEADKEARGLNINENADFIEKAGGMEKIF 487
Query: 484 NLQSNANEKIYEKAFKIIEKYFSDEDDVVDESMAPQTAGNTFGFGSNVNQQFNFN 538
N Q N N+KIYEKA+KIIE YF +E+D VDE+MAPQ AGNTFGFGSNVNQQFNFN
Sbjct: 488 NCQQNENDKIYEKAYKIIETYFGEEEDAVDETMAPQNAGNTFGFGSNVNQQFNFN 542
>SPCC962.03c [U] KOG0166 Karyopherin (importin) alpha
Length = 542
Score = 607 bits (1566), Expect = e-173
Identities = 299/525 (56%), Positives = 400/525 (75%), Gaps = 7/525 (1%)
Query: 6 SSKFVPEYRRTNFKNKGRFSADELRRRRDVQQVELRKVKRDEALAKRRNFNAPVGNXXXX 65
SS+F+PE+RR N+K KG F ADELRRRR+ QQ+E+RK KR+E L KRRN V
Sbjct: 4 SSRFIPEHRRQNYKGKGTFQADELRRRRETQQIEIRKQKREENLNKRRNL---VDVQEPA 60
Query: 66 XXXXXXXXXXXFYRQLQQELPAMLEQIHSNDLQQQLAVTVKFRQVLSREHRPPIDLVIST 125
+L+ +LP +L+ ++S+D++ Q+ T KFR+ LS+E PPI VI
Sbjct: 61 EETIPLEQDKENDLELELQLPDLLKALYSDDIEAQIQATAKFRKALSKETNPPIQKVIDA 120
Query: 126 GVVPTLVQFMSENQPEMLQLEAAWALTNIASGTSEQTRVVVDAGAVPLFIQLLYSNSVEV 185
GVVP V+F+S ++ +L+ EA+WALTN+ASG+S QT VVV+A AVP+F+ LL S+ +V
Sbjct: 121 GVVPRFVEFLS-HENNLLKFEASWALTNVASGSSNQTHVVVEANAVPVFVSLLSSSEQDV 179
Query: 186 KEQAIWALGNVAGDSTDYRDYVLQCGAMQPILYLFELNKT-SLIRTATWTLSNLCRGKKP 244
+EQA+WALGN+AGDS RD+VLQCG ++P+L + E N+ S++R +TWTLSN+CRGK P
Sbjct: 180 REQAVWALGNIAGDSPMCRDHVLQCGVLEPLLNIIESNRRLSMLRNSTWTLSNMCRGKNP 239
Query: 245 QPDWSIVSQALPTLSKLIYSMDTETLVDACWAISYLSDGPVNSIQAVVDARIPKRLVELL 304
QPDW+ +SQ +P LSKLIY++D + LVDA WAISYLSDG IQA++DA IP+RLVELL
Sbjct: 240 QPDWNSISQVIPVLSKLIYTLDEDVLVDALWAISYLSDGANEKIQAIIDAGIPRRLVELL 299
Query: 305 SHQSTLVQTPALRAVGNIVTGNDLQTQIVINCGALAALRNLLASPKESIRKEACWTISNI 364
H S VQTPALR+VGNIVTG+D+QTQ++INCGAL+AL +LL+SP++ +RKEACWTISNI
Sbjct: 300 MHPSAQVQTPALRSVGNIVTGDDVQTQVIINCGALSALLSLLSSPRDGVRKEACWTISNI 359
Query: 365 TAGNTEQIQAVIDANLIPPLIRLLETAEYKTKKEACWAISNASSGGLHKPEIIRYLVSQG 424
TAGN+ QIQ VI+AN+IPPLI LL TA++K +KEACWAISNA+SGG +P+ IRYLV QG
Sbjct: 360 TAGNSSQIQYVIEANIIPPLIHLLTTADFKIQKEACWAISNATSGGARRPDQIRYLVEQG 419
Query: 425 CIKPLCDLLEIADNRIIEVTLDAIENILKMGEMDREVRGIAVNENADFIEKAGGMEKIFN 484
IKPLC+LL DN+II+V LD IENIL++GE+DR +N A ++E AGGM+ I
Sbjct: 420 AIKPLCNLLACQDNKIIQVALDGIENILRVGELDRANNPDKINLYAVYVEDAGGMDLIHE 479
Query: 485 LQSNANEKIYEKAFKIIEKYFSDEDDVVDESMAPQTAGNTFGFGS 529
Q+++N +IY+KA+ IIEK+F +ED++ E + P+T G+TF FG+
Sbjct: 480 CQNSSNSEIYQKAYNIIEKFFGEEDEI--EELEPETVGDTFTFGT 522
>SPBC1604.08c [U] KOG0166 Karyopherin (importin) alpha
Length = 539
Score = 599 bits (1545), Expect = e-171
Identities = 309/526 (58%), Positives = 392/526 (73%), Gaps = 6/526 (1%)
Query: 14 RRTNFKNKGRFSADELRRRRDVQQVELRKVKRDEALAKRRNFNAPVGNXXXXXXXXXXXX 73
RR+ FK+KG F ADELRR+R+ QQ+E+RK KR+E+L KRRN NA + N
Sbjct: 9 RRSRFKSKGVFKADELRRQREEQQIEIRKQKREESLNKRRNLNAVLQNDIDVEEEADQSQ 68
Query: 74 XXXFYRQLQQELPAMLEQIHSNDLQQQLAVTVKFRQVLSREHRPPIDLVISTGVVPTLVQ 133
+Q++ E P + + S+D++ QL KFR+ LS+E PPID VI+ GVV VQ
Sbjct: 69 VQ-MEQQMKDEFPKLTADVMSDDIELQLGAVTKFRKYLSKETHPPIDQVIACGVVDRFVQ 127
Query: 134 FMSENQPEMLQLEAAWALTNIASGTSEQTRVVVDAGAVPLFIQLLYSNSVEVKEQAIWAL 193
F+ E++ +LQ EAAWALTNIASGT++QTR+VVD+GAVP FIQLL S +V+EQ +WAL
Sbjct: 128 FL-ESEHHLLQFEAAWALTNIASGTTDQTRIVVDSGAVPRFIQLLSSPEKDVREQVVWAL 186
Query: 194 GNVAGDSTDYRDYVLQCGAMQPILYLFELNKT--SLIRTATWTLSNLCRGKKPQPDWSIV 251
GN+AGDS+ RDYVL G +QP+L + + + + S++R ATWTLSNLCRGK P P+WS +
Sbjct: 187 GNIAGDSSACRDYVLGNGVLQPLLNILQSSASDVSMLRNATWTLSNLCRGKNPPPNWSTI 246
Query: 252 SQALPTLSKLIYSMDTETLVDACWAISYLSDGPVNSIQAVVDARIPKRLVELLSHQSTLV 311
S A+P L+KL+YS D E +VDACWAISYLSDGP I A++D RLVELLS S +
Sbjct: 247 SVAVPILAKLLYSEDVEIIVDACWAISYLSDGPNEKIGAILDVGCAPRLVELLSSPSVNI 306
Query: 312 QTPALRAVGNIVTGNDLQTQIVINCGALAALRNLLASPKESIRKEACWTISNITAGNTEQ 371
QTPALR+VGNIVTG D QTQI+I+CGAL A +LL+ KE+IRKEACWTISNITAGNT+Q
Sbjct: 307 QTPALRSVGNIVTGTDAQTQIIIDCGALNAFPSLLSHQKENIRKEACWTISNITAGNTQQ 366
Query: 372 IQAVIDANLIPPLIRLLETAEYKTKKEACWAISNASSGGLHKPEIIRYLVSQGCIKPLCD 431
IQA+I++NLIPPL+ LL A+YKTKKEACWAISNA+SGGL +P+ IRYLVSQG IKPLCD
Sbjct: 367 IQAIIESNLIPPLVHLLSYADYKTKKEACWAISNATSGGLGQPDQIRYLVSQGVIKPLCD 426
Query: 432 LLEIADNRIIEVTLDAIENILKMGEMDREVRGIAVNENADFIEKAGGMEKIFNLQSNANE 491
+L +DN+II+V LDAIENILK+GEMDR + +N+ A ++E+AGGM+ I +LQS+ N
Sbjct: 427 MLNGSDNKIIQVALDAIENILKVGEMDRTMDLENINQYAVYVEEAGGMDMIHDLQSSGNN 486
Query: 492 KIYEKAFKIIEKYFSDEDDVVDESMAPQTAGNTFGFGSNVNQQFNF 537
IY KA+ IIEKYFSDED V E +AP+T F FG+ Q F
Sbjct: 487 DIYLKAYSIIEKYFSDEDAV--EDLAPETENGAFTFGNGPQAQGEF 530
>Hs6912478 [U] KOG0166 Karyopherin (importin) alpha
Length = 536
Score = 522 bits (1345), Expect = e-148
Identities = 275/515 (53%), Positives = 366/515 (70%), Gaps = 20/515 (3%)
Query: 13 YRRTNFKNKGRFSADELRRRRDVQQVELRKVKRDEALAKRRNFN------APVGNXXXXX 66
YR ++KN + +E+RRRR+ + ++LRK KR++ L KRRN A +
Sbjct: 12 YRMKSYKNNA-LNPEEMRRRREEEGIQLRKQKREQQLFKRRNVELINEEAAMFDSLLMDS 70
Query: 67 XXXXXXXXXXFYRQLQQELPAMLEQIHSNDLQQQLAVTVKFRQVLSREHRPPIDLVISTG 126
R+ M+E + S+D QLA T KFR++LS+E PPID VI+T
Sbjct: 71 YVSSTTGESVITRE-------MVEMLFSDDSDLQLATTQKFRKLLSKEPSPPIDEVINTP 123
Query: 127 -VVPTLVQFMSENQPEMLQLEAAWALTNIASGTSEQTRVVVDAGAVPLFIQLLYSNSVEV 185
VV V+F+ N+ LQ EAAWALTNIASGTS+QT++V++AGAVP+FI+LL S+ +V
Sbjct: 124 RVVDRFVEFLKRNENCTLQFEAAWALTNIASGTSQQTKIVIEAGAVPIFIELLNSDFEDV 183
Query: 186 KEQAIWALGNVAGDSTDYRDYVLQCGAMQPILYLF-ELNKTSLIRTATWTLSNLCRGKKP 244
+EQA+WALGN+AGDS+ RDYVL C + P+L L + + ++ R A W LSNLCRGK P
Sbjct: 184 QEQAVWALGNIAGDSSVCRDYVLNCSILNPLLTLLTKSTRLTMTRNAVWALSNLCRGKNP 243
Query: 245 QPDWSIVSQALPTLSKLIYSMDTETLVDACWAISYLSDGPVNSIQAVVDARIPKRLVELL 304
P+++ VS LP LS+L++S D++ L DACWA+SYLSDGP IQAV+D+ + +RLVELL
Sbjct: 244 PPEFAKVSPCLPVLSRLLFSSDSDLLADACWALSYLSDGPNEKIQAVIDSGVCRRLVELL 303
Query: 305 SHQSTLVQTPALRAVGNIVTGNDLQTQIVINCGALAALRNLLASPKESIRKEACWTISNI 364
H V +PALRAVGNIVTG+D+QTQ+++NC AL L +LL+SPKESIRKEACWTISNI
Sbjct: 304 MHNDYKVASPALRAVGNIVTGDDIQTQVILNCSALPCLLHLLSSPKESIRKEACWTISNI 363
Query: 365 TAGNTEQIQAVIDANLIPPLIRLLETAEYKTKKEACWAISNASSGGLHKPEIIRYLVSQG 424
TAGN QIQAVIDAN+ P LI +L+ AE++T+KEA WAI+NA+SGG PE IRYLVS G
Sbjct: 364 TAGNRAQIQAVIDANIFPVLIEILQKAEFRTRKEAAWAITNATSGG--TPEQIRYLVSLG 421
Query: 425 CIKPLCDLLEIADNRIIEVTLDAIENILKMGEMDREVRGIAVNENADFIEKAGGMEKIFN 484
CIKPLCDLL + D++I++V L+ +ENIL++GE + + G VN IE+A G++KI
Sbjct: 422 CIKPLCDLLTVMDSKIVQVALNGLENILRLGEQEGKRSGSGVNPYCGLIEEAYGLDKIEF 481
Query: 485 LQSNANEKIYEKAFKIIEKYFSDEDDVVDESMAPQ 519
LQS+ N++IY+KAF +IE YF EDD D S+APQ
Sbjct: 482 LQSHENQEIYQKAFDLIEHYFGVEDD--DSSLAPQ 514
>Hs22043735 [U] KOG0166 Karyopherin (importin) alpha
Length = 538
Score = 514 bits (1325), Expect = e-146
Identities = 274/517 (52%), Positives = 361/517 (68%), Gaps = 19/517 (3%)
Query: 13 YRRTNFKNKGRFSADELRRRRDVQQVELRKVKRDEALAKRRNFNAPVGNXXXXXXXXXXX 72
+R ++KNK + DE+RRRR+ + ++LRK KR+E L KRRN V
Sbjct: 9 FRLKSYKNKS-LNPDEMRRRREEEGLQLRKQKREEQLFKRRN----VATAEEETEEEVMS 63
Query: 73 XXXXFYRQLQQELPA--------MLEQIHSNDLQQQLAVTVKFRQVLSREHRPPIDLVIS 124
Q+ A M+E I S +QQL+ T KFR++LS+E PPID VIS
Sbjct: 64 DGGFHEAQISNMEMAPGGVITSDMIEMIFSKSPEQQLSATQKFRKLLSKEPNPPIDEVIS 123
Query: 125 T-GVVPTLVQFMSENQPEMLQLEAAWALTNIASGTSEQTRVVVDAGAVPLFIQLLYSNSV 183
T GVV V+F+ + LQ E+AW LTNIASG S QTR+V+ AGAVP+FI+LL S
Sbjct: 124 TPGVVARFVEFLKRKENCTLQFESAWVLTNIASGNSLQTRIVIQAGAVPIFIELLSSEFE 183
Query: 184 EVKEQAIWALGNVAGDSTDYRDYVLQCGAMQPILYLF-ELNKTSLIRTATWTLSNLCRGK 242
+V+EQA+WALGN+AGDST RDYVL C + P+L LF + N+ ++ R A W LSNLCRGK
Sbjct: 184 DVQEQAVWALGNIAGDSTMCRDYVLDCNILPPLLQLFSKQNRLTMTRNAVWALSNLCRGK 243
Query: 243 KPQPDWSIVSQALPTLSKLIYSMDTETLVDACWAISYLSDGPVNSIQAVVDARIPKRLVE 302
P P+++ VS L LS L++ DT+ L DACWA+SYLSDGP + IQAV+DA + +RLVE
Sbjct: 244 SPPPEFAKVSPCLNVLSWLLFVSDTDVLADACWALSYLSDGPNDKIQAVIDAGVCRRLVE 303
Query: 303 LLSHQSTLVQTPALRAVGNIVTGNDLQTQIVINCGALAALRNLLASPKESIRKEACWTIS 362
LL H V +PALRAVGNIVTG+D+QTQ+++NC AL +L +LL+SPKESI+KEACWTIS
Sbjct: 304 LLMHNDYKVVSPALRAVGNIVTGDDIQTQVILNCSALQSLLHLLSSPKESIKKEACWTIS 363
Query: 363 NITAGNTEQIQAVIDANLIPPLIRLLETAEYKTKKEACWAISNASSGGLHKPEIIRYLVS 422
NITAGN QIQ VIDAN+ P LI +L+TAE++T+KEA WAI+NA+SGG E I+YLV
Sbjct: 364 NITAGNRAQIQTVIDANIFPALISILQTAEFRTRKEAAWAITNATSGG--SAEQIKYLVE 421
Query: 423 QGCIKPLCDLLEIADNRIIEVTLDAIENILKMGEMDREVRGIAVNENADFIEKAGGMEKI 482
GCIKPLCDLL + D++I++V L+ +ENIL++GE + + G +N IE+A G++KI
Sbjct: 422 LGCIKPLCDLLTVMDSKIVQVALNGLENILRLGEQEAKRNGTGINPYCALIEEAYGLDKI 481
Query: 483 FNLQSNANEKIYEKAFKIIEKYFSDEDDVVDESMAPQ 519
LQS+ N++IY+KAF +IE YF ED+ D S+APQ
Sbjct: 482 EFLQSHENQEIYQKAFDLIEHYFGTEDE--DSSIAPQ 516
>Hs4504903 [U] KOG0166 Karyopherin (importin) alpha
Length = 536
Score = 513 bits (1321), Expect = e-145
Identities = 269/515 (52%), Positives = 359/515 (69%), Gaps = 9/515 (1%)
Query: 13 YRRTNFKNKGRFSADELRRRRDVQQVELRKVKRDEALAKRRNFNAPVGNXXXXXXXXXXX 72
YR ++KNK + E+RRRR+ + ++LRK KR+E L KRRN P +
Sbjct: 9 YRMKSYKNKA-LNPQEMRRRREEEGIQLRKQKREEQLFKRRNVYLPRNDESMLESPIQDS 67
Query: 73 XXXXFYRQLQQELPA--MLEQIHSNDLQQQLAVTVKFRQVLSREHRPPIDLVIST-GVVP 129
++ + M++ I SN+ QQL T KFR++LS+E PPID VI GVV
Sbjct: 68 DISSTVPIPEEGVVTTDMVQMIFSNNADQQLTATQKFRKLLSKEPNPPIDQVIQKPGVVQ 127
Query: 130 TLVQFMSENQPEMLQLEAAWALTNIASGTSEQTRVVVDAGAVPLFIQLLYSNSVEVKEQA 189
V+F+ N+ LQ EAAWALTNIASGT T+VV++ GAVP+FI+LL S +V+EQA
Sbjct: 128 RFVKFLERNENCTLQFEAAWALTNIASGTFLHTKVVIETGAVPIFIKLLNSEHEDVQEQA 187
Query: 190 IWALGNVAGDSTDYRDYVLQCGAMQPILYLF-ELNKTSLIRTATWTLSNLCRGKKPQPDW 248
+WALGN+AGD+ + RD+VL C + P+L L N+ + R A W LSNLCRGK P P++
Sbjct: 188 VWALGNIAGDNAECRDFVLNCEILPPLLELLTNSNRLTTTRNAVWALSNLCRGKNPPPNF 247
Query: 249 SIVSQALPTLSKLIYSMDTETLVDACWAISYLSDGPVNSIQAVVDARIPKRLVELLSHQS 308
S VS L LS+L++S D + L D CWA+SYLSDGP + IQAV+D+ + +RLVELL H
Sbjct: 248 SKVSPCLNVLSRLLFSSDPDVLADVCWALSYLSDGPNDKIQAVIDSGVCRRLVELLMHND 307
Query: 309 TLVQTPALRAVGNIVTGNDLQTQIVINCGALAALRNLLASPKESIRKEACWTISNITAGN 368
V +PALRAVGNIVTG+D+QTQ+++NC AL L +LL+SPKESIRKEACWT+SNITAGN
Sbjct: 308 YKVVSPALRAVGNIVTGDDIQTQVILNCSALPCLLHLLSSPKESIRKEACWTVSNITAGN 367
Query: 369 TEQIQAVIDANLIPPLIRLLETAEYKTKKEACWAISNASSGGLHKPEIIRYLVSQGCIKP 428
QIQAVIDAN+ P LI +L+ AE++T+KEA WAI+NA+SGG PE IRYLV+ GCIKP
Sbjct: 368 RAQIQAVIDANIFPVLIEILQKAEFRTRKEAAWAITNATSGG--TPEQIRYLVALGCIKP 425
Query: 429 LCDLLEIADNRIIEVTLDAIENILKMGEMDREVRGIAVNENADFIEKAGGMEKIFNLQSN 488
LCDLL + D++I++V L+ +ENIL++GE + + GI +N IE+A G++KI LQS+
Sbjct: 426 LCDLLTVMDSKIVQVALNGLENILRLGEQESKQNGIGINPYCALIEEAYGLDKIEFLQSH 485
Query: 489 ANEKIYEKAFKIIEKYFSDEDDVVDESMAPQTAGN 523
N++IY+KAF +IE YF E+D D S+ PQ N
Sbjct: 486 ENQEIYQKAFDLIEHYFGVEED--DPSIVPQVDEN 518
>Hs4504895 [U] KOG0166 Karyopherin (importin) alpha
Length = 538
Score = 511 bits (1317), Expect = e-145
Identities = 273/517 (52%), Positives = 360/517 (68%), Gaps = 19/517 (3%)
Query: 13 YRRTNFKNKGRFSADELRRRRDVQQVELRKVKRDEALAKRRNFNAPVGNXXXXXXXXXXX 72
+R ++KNK + DE+RRRR+ + ++LRK KR+E L KRRN V
Sbjct: 9 FRLKSYKNKS-LNPDEMRRRREEEGLQLRKQKREEQLFKRRN----VATAEEETEEEVMS 63
Query: 73 XXXXFYRQLQQELPA--------MLEQIHSNDLQQQLAVTVKFRQVLSREHRPPIDLVIS 124
Q+ A M+E I S +QQL+ T KFR++LS+E PPID VIS
Sbjct: 64 DGGFHEAQISNMEMAPGGVITSDMIEMIFSKSPEQQLSATQKFRKLLSKEPNPPIDEVIS 123
Query: 125 T-GVVPTLVQFMSENQPEMLQLEAAWALTNIASGTSEQTRVVVDAGAVPLFIQLLYSNSV 183
T GVV V+F+ + LQ E+AW LTNIASG S QTR+V+ A AVP+FI+LL S
Sbjct: 124 TPGVVARFVEFLKRKENCSLQFESAWVLTNIASGNSLQTRIVIQARAVPIFIELLSSEFE 183
Query: 184 EVKEQAIWALGNVAGDSTDYRDYVLQCGAMQPILYLF-ELNKTSLIRTATWTLSNLCRGK 242
+V+EQA+WALGN+AGDST RDYVL C + P+L LF + N+ ++ R A W LSNLCRGK
Sbjct: 184 DVQEQAVWALGNIAGDSTMCRDYVLDCNILPPLLQLFSKQNRLTMTRNAVWALSNLCRGK 243
Query: 243 KPQPDWSIVSQALPTLSKLIYSMDTETLVDACWAISYLSDGPVNSIQAVVDARIPKRLVE 302
P P+++ VS L LS L++ DT+ L DACWA+SYLSDGP + IQAV+DA + +RLVE
Sbjct: 244 SPPPEFAKVSPCLNVLSWLLFVSDTDVLADACWALSYLSDGPNDKIQAVIDAGVCRRLVE 303
Query: 303 LLSHQSTLVQTPALRAVGNIVTGNDLQTQIVINCGALAALRNLLASPKESIRKEACWTIS 362
LL H V +PALRAVGNIVTG+D+QTQ+++NC AL +L +LL+SPKESI+KEACWTIS
Sbjct: 304 LLMHNDYKVVSPALRAVGNIVTGDDIQTQVILNCSALQSLLHLLSSPKESIKKEACWTIS 363
Query: 363 NITAGNTEQIQAVIDANLIPPLIRLLETAEYKTKKEACWAISNASSGGLHKPEIIRYLVS 422
NITAGN QIQ VIDAN+ P LI +L+TAE++T+KEA WAI+NA+SGG E I+YLV
Sbjct: 364 NITAGNRAQIQTVIDANIFPALISILQTAEFRTRKEAAWAITNATSGG--SAEQIKYLVE 421
Query: 423 QGCIKPLCDLLEIADNRIIEVTLDAIENILKMGEMDREVRGIAVNENADFIEKAGGMEKI 482
GCIKPLCDLL + D++I++V L+ +ENIL++GE + + G +N IE+A G++KI
Sbjct: 422 LGCIKPLCDLLTVMDSKIVQVALNGLENILRLGEQEAKRNGTGINPYCALIEEAYGLDKI 481
Query: 483 FNLQSNANEKIYEKAFKIIEKYFSDEDDVVDESMAPQ 519
LQS+ N++IY+KAF +IE YF ED+ D S+APQ
Sbjct: 482 EFLQSHENQEIYQKAFDLIEHYFGTEDE--DSSIAPQ 516
>At1g09270 [U] KOG0166 Karyopherin (importin) alpha
Length = 538
Score = 493 bits (1269), Expect = e-139
Identities = 271/515 (52%), Positives = 351/515 (67%), Gaps = 15/515 (2%)
Query: 26 ADELRRRRDVQQVELRKVKRDEALAKRRNFNAPVGNXXXXXXXXXXXXXXXFYRQLQQEL 85
ADE RRRR+ VE+RK KR+++L K+R + + + +
Sbjct: 22 ADEARRRREDNLVEIRKNKREDSLLKKRREGMMLQQQLPLGAGLDGPQTAAAVEKRLEGI 81
Query: 86 PAMLEQIHSNDLQQQLAVTVKFRQVLSREHRPPIDLVISTGVVPTLVQFMSENQPEMLQL 145
P M++ ++S+D Q QL T +FR++LS E PPID VI GV+P V+F+ + LQ
Sbjct: 82 PMMVQGVYSDDPQAQLEATTQFRKLLSIERSPPIDEVIKAGVIPRFVEFLGRHDHPQLQF 141
Query: 146 EAAWALTNIASGTSEQTRVVVDAGAVPLFIQLLYSNSVEVKEQAIWALGNVAGDSTDYRD 205
EAAWALTN+ASGTS+ TRVV++ GAVP+F++LL S S +V+EQA+WALGNVAGDS + R+
Sbjct: 142 EAAWALTNVASGTSDHTRVVIEQGAVPIFVKLLTSASDDVREQAVWALGNVAGDSPNCRN 201
Query: 206 YVLQCGAMQPIL-YLFELNKTSLIRTATWTLSNLCRGKKPQPDWSIVSQALPTLSKLIYS 264
VL GA++P+L L E +K S++R ATWTLSN CRGK P P + V ALP L +LIY
Sbjct: 202 LVLNYGALEPLLAQLNENSKLSMLRNATWTLSNFCRGKPPTP-FEQVKPALPILRQLIYL 260
Query: 265 MDTETLVDACWAISYLSDGPVNSIQAVVDARIPKRLVELLSHQSTLVQTPALRAVGNIVT 324
D E L DACWA+SYLSDGP + IQAV++A + RLVELL HQS V PALR VGNIVT
Sbjct: 261 NDEEVLTDACWALSYLSDGPNDKIQAVIEAGVCPRLVELLGHQSPTVLIPALRTVGNIVT 320
Query: 325 GNDLQTQIVINCGALAALRNLLA-SPKESIRKEACWTISNITAGNTEQIQAVIDANLIPP 383
G+D QTQ +I G L L NLL + K+SI+KEACWTISNITAGN QI+AV+ A +I P
Sbjct: 321 GDDSQTQFIIESGVLPHLYNLLTQNHKKSIKKEACWTISNITAGNKLQIEAVVGAGIILP 380
Query: 384 LIRLLETAEYKTKKEACWAISNASSGGLHKPEIIRYLVSQGCIKPLCDLLEIADNRIIEV 443
L+ LL+ AE+ KKEA WAISNA+SGG H E I+YLV+QGCIKPLCDLL D RI+ V
Sbjct: 381 LVHLLQNAEFDIKKEAAWAISNATSGGSH--EQIQYLVTQGCIKPLCDLLICPDPRIVTV 438
Query: 444 TLDAIENILKMGEMDREV-RGIAVNENADFIEKAGGMEKIFNLQSNANEKIYEKAFKIIE 502
L+ +ENILK+GE D+E+ VN A IE++ G++K+ NLQS+ N +IYEKA KI+E
Sbjct: 439 CLEGLENILKVGEADKEMGLNSGVNLYAQIIEESDGLDKVENLQSHDNNEIYEKAVKILE 498
Query: 503 KYFSDEDDVVDESMAPQTAGNTFGFGSNVNQQFNF 537
+Y+++E +E Q GN N Q FNF
Sbjct: 499 RYWAEE----EEEQILQDGGN-----DNSQQAFNF 524
>At3g06720 [U] KOG0166 Karyopherin (importin) alpha
Length = 532
Score = 484 bits (1245), Expect = e-136
Identities = 282/537 (52%), Positives = 354/537 (65%), Gaps = 24/537 (4%)
Query: 12 EYRRTNFKNKGRFSADELRRRRDVQQVELRKVKRDEALAKRRNFNAPVGNXXXXXXXXXX 71
E RR +K A+E RRRR+ VE+RK KR+E+L K+R
Sbjct: 10 EVRRNRYKVA--VDAEEGRRRREDNMVEIRKSKREESLMKKRR------EGMQALQGFPS 61
Query: 72 XXXXXFYRQLQQELPAMLEQIHSNDLQQQLAVTVKFRQVLSREHRPPIDLVISTGVVPTL 131
++L L M+ + S+D QL T +FR++LS E PPI+ VIS GVVP
Sbjct: 62 ASAASVDKKLDS-LKDMVAGVWSDDPALQLESTTQFRKLLSIERSPPIEEVISAGVVPRF 120
Query: 132 VQFMSENQPEMLQLEAAWALTNIASGTSEQTRVVVDAGAVPLFIQLLYSNSVEVKEQAIW 191
V+F+ + +Q EAAWALTNIASGTS+ T+VV+D AVP+F+QLL S S +V+EQA+W
Sbjct: 121 VEFLKKEDYPAIQFEAAWALTNIASGTSDHTKVVIDHNAVPIFVQLLASPSDDVREQAVW 180
Query: 192 ALGNVAGDSTDYRDYVLQCGAMQPIL-YLFELNKTSLIRTATWTLSNLCRGKKPQPDWSI 250
ALGNVAGDS RD VL CGA+ P+L L E K S++R ATWTLSN CRG KPQP +
Sbjct: 181 ALGNVAGDSPRCRDLVLGCGALLPLLNQLNEHAKLSMLRNATWTLSNFCRG-KPQPHFDQ 239
Query: 251 VSQALPTLSKLIYSMDTETLVDACWAISYLSDGPVNSIQAVVDARIPKRLVELLSHQSTL 310
V ALP L +LI+S D E L DACWA+SYLSDG + IQ V+ A + +LVELL H S
Sbjct: 240 VKPALPALERLIHSDDEEVLTDACWALSYLSDGTNDKIQTVIQAGVVPKLVELLLHHSPS 299
Query: 311 VQTPALRAVGNIVTGNDLQTQIVINCGALAALRNLLA-SPKESIRKEACWTISNITAGNT 369
V PALR VGNIVTG+D+QTQ VIN GAL L NLL + K+SI+KEACWTISNITAGN
Sbjct: 300 VLIPALRTVGNIVTGDDIQTQCVINSGALPCLANLLTQNHKKSIKKEACWTISNITAGNK 359
Query: 370 EQIQAVIDANLIPPLIRLLETAEYKTKKEACWAISNASSGGLHKPEIIRYLVSQGCIKPL 429
+QIQ V++ANLI PL+ LL+ AE+ KKEA WAISNA+SGG H + I+YLV QGCIKPL
Sbjct: 360 DQIQTVVEANLISPLVSLLQNAEFDIKKEAAWAISNATSGGSH--DQIKYLVEQGCIKPL 417
Query: 430 CDLLEIADNRIIEVTLDAIENILKMGEMDREVRGIA-VNENADFIEKAGGMEKIFNLQSN 488
CDLL D RII V L+ +ENILK+GE ++ + +N A I+ A G+EKI NLQS+
Sbjct: 418 CDLLVCPDPRIITVCLEGLENILKVGEAEKNLGHTGDMNYYAQLIDDAEGLEKIENLQSH 477
Query: 489 ANEKIYEKAFKIIEKYFSDEDDVVDESMAPQ-TAGNTFGFGSNVNQQ------FNFN 538
N +IYEKA KI+E Y+ +E+D DE+ P G+ GF NQ FNF+
Sbjct: 478 DNNEIYEKAVKILETYWLEEED--DETQQPPGVDGSQAGFQFGGNQAPVPSGGFNFS 532
>At1g02690 [U] KOG0166 Karyopherin (importin) alpha
Length = 538
Score = 483 bits (1243), Expect = e-136
Identities = 280/539 (51%), Positives = 357/539 (65%), Gaps = 24/539 (4%)
Query: 12 EYRRTNFKNKGRFSADELRRRRDVQQVELRKVKRDEALAKRRN--FNAPVGNXXXXXXXX 69
E RR +K ADE RRRR+ VE+RK KR+E L K+R FN + +
Sbjct: 10 EVRRNRYKVS--VDADEGRRRREDNMVEIRKNKREENLQKKRREGFNPSMASQPGQDFSS 67
Query: 70 XXXXXXXFYRQLQQELPAMLEQIHSNDLQQQLAVTVKFRQVLSREHRPPIDLVISTGVVP 129
+ + M+ + S D QL T FR++LS E PPI+ V+ +GVVP
Sbjct: 68 SLPTETRL-----ENIQQMIAGVMSEDRDLQLEATASFRRLLSIERNPPINEVVQSGVVP 122
Query: 130 TLVQFMSENQPEMLQLEAAWALTNIASGTSEQTRVVVDAGAVPLFIQLLYSNSVEVKEQA 189
+VQF+S + LQ EAAWALTNIASGTSE TRV++D+GAVPLF++LL S S EV+EQA
Sbjct: 123 HIVQFLSRDDFTQLQFEAAWALTNIASGTSENTRVIIDSGAVPLFVKLLSSASEEVREQA 182
Query: 190 IWALGNVAGDSTDYRDYVLQCGAMQPILYLF-ELNKTSLIRTATWTLSNLCRGKKPQPDW 248
+WALGNVAGDS RD+VL C AM +L F E +K S++R ATWTLSN CRG KPQP +
Sbjct: 183 VWALGNVAGDSPKCRDHVLSCEAMMSLLAQFHEHSKLSMLRNATWTLSNFCRG-KPQPAF 241
Query: 249 SIVSQALPTLSKLIYSMDTETLVDACWAISYLSDGPVNSIQAVVDARIPKRLVELLSHQS 308
ALP L +L++S D E L DA WA+SYLSDG IQ V+DA + RLV+LL+H S
Sbjct: 242 EQTKAALPALERLLHSTDEEVLTDASWALSYLSDGTNEKIQTVIDAGVIPRLVQLLAHPS 301
Query: 309 TLVQTPALRAVGNIVTGNDLQTQIVINCGALAALRNLLASP-KESIRKEACWTISNITAG 367
V PALR +GNIVTG+D+QTQ VI+ AL L NLL + K+SI+KEACWTISNITAG
Sbjct: 302 PSVLIPALRTIGNIVTGDDIQTQAVISSQALPGLLNLLKNTYKKSIKKEACWTISNITAG 361
Query: 368 NTEQIQAVIDANLIPPLIRLLETAEYKTKKEACWAISNASSGGLHKPEIIRYLVSQGCIK 427
NT QIQ V A +I PLI LLE E++ KKEA WAISNA+SGG H + I++LVSQGCI+
Sbjct: 362 NTSQIQEVFQAGIIRPLINLLEIGEFEIKKEAVWAISNATSGGNH--DQIKFLVSQGCIR 419
Query: 428 PLCDLLEIADNRIIEVTLDAIENILKMGEMDREVRGIAVNEN--ADFIEKAGGMEKIFNL 485
PLCDLL D R++ VTL+ +ENILK+GE ++ + G N+N A IE A G++KI NL
Sbjct: 420 PLCDLLPCPDPRVVTVTLEGLENILKVGEAEKNL-GNTGNDNLYAQMIEDADGLDKIENL 478
Query: 486 QSNANEKIYEKAFKIIEKYFS---DEDDV--VDESMAPQTAGNTFG--FGSNVNQQFNF 537
QS+ N +IYEKA KI+E Y++ +E+D+ VD Q++G FG G+ FNF
Sbjct: 479 QSHDNNEIYEKAVKILESYWAADDEEEDIGGVDAPENVQSSGFQFGNQSGNAPTGGFNF 537
>At4g02150 [U] KOG0166 Karyopherin (importin) alpha
Length = 531
Score = 478 bits (1229), Expect = e-134
Identities = 273/532 (51%), Positives = 359/532 (67%), Gaps = 17/532 (3%)
Query: 12 EYRRTNFKNKGRFSADELRRRRDVQQVELRKVKRDEALAKRRNFNAPVGNXXXXXXXXXX 71
E RR +K A+E RRRR+ VE+RK KR+E L K+R ++
Sbjct: 10 EVRRNRYKVA--VDAEEGRRRREDNLVEIRKNKREENLQKKRFTSSMAFGSATGQTEQDL 67
Query: 72 XXXXXFYRQLQQELPAMLEQIHSNDLQQQLAVTVKFRQVLSREHRPPIDLVISTGVVPTL 131
QL+ LPAM+ I S D QL T R++LS E PPI+ V+ +GVVP +
Sbjct: 68 SSA----NQLKDNLPAMVAGIWSEDSNSQLEATNLLRKLLSIEQNPPINEVVQSGVVPRV 123
Query: 132 VQFMSENQPEMLQLEAAWALTNIASGTSEQTRVVVDAGAVPLFIQLLYSNSVEVKEQAIW 191
V+F+S + LQ EAAWALTNIASGTSE T V++++GAVP+FIQLL S S +V+EQA+W
Sbjct: 124 VKFLSRDDFPKLQFEAAWALTNIASGTSENTNVIIESGAVPIFIQLLSSASEDVREQAVW 183
Query: 192 ALGNVAGDSTDYRDYVLQCGAMQPILYLFELN-KTSLIRTATWTLSNLCRGKKPQPDWSI 250
ALGNVAGDS RD VL GAM P+L F N K S++R ATWTLSN CRG KP P +
Sbjct: 184 ALGNVAGDSPKCRDLVLSYGAMTPLLSQFNENTKLSMLRNATWTLSNFCRG-KPPPAFEQ 242
Query: 251 VSQALPTLSKLIYSMDTETLVDACWAISYLSDGPVNSIQAVVDARIPKRLVELLSHQSTL 310
ALP L +L+ SMD E L DACWA+SYLSD + IQAV++A + RL++LL H S
Sbjct: 243 TQPALPVLERLVQSMDEEVLTDACWALSYLSDNSNDKIQAVIEAGVVPRLIQLLGHSSPS 302
Query: 311 VQTPALRAVGNIVTGNDLQTQIVINCGALAALRNLLASP-KESIRKEACWTISNITAGNT 369
V PALR +GNIVTG+DLQTQ+V++ AL L NLL + K+SI+KEACWTISNITAGN
Sbjct: 303 VLIPALRTIGNIVTGDDLQTQMVLDQQALPCLLNLLKNNYKKSIKKEACWTISNITAGNA 362
Query: 370 EQIQAVIDANLIPPLIRLLETAEYKTKKEACWAISNASSGGLHKPEIIRYLVSQGCIKPL 429
+QIQAVIDA +I L+ +L++AE++ KKEA W ISNA+SGG H + I+++VSQGCIKPL
Sbjct: 363 DQIQAVIDAGIIQSLVWVLQSAEFEVKKEAAWGISNATSGGTH--DQIKFMVSQGCIKPL 420
Query: 430 CDLLEIADNRIIEVTLDAIENILKMGEMDREVRGIAVNEN--ADFIEKAGGMEKIFNLQS 487
CDLL D +++ V L+A+ENIL +GE ++ + G +N A I++A G+EKI NLQS
Sbjct: 421 CDLLTCPDLKVVTVCLEALENILVVGEAEKNL-GHTGEDNLYAQMIDEAEGLEKIENLQS 479
Query: 488 NANEKIYEKAFKIIEKYFSD--EDDVVDESMAPQTAGNTFGFGSNVNQQFNF 537
+ N IY+KA KI+E ++++ E++ DE+ APQ +G FG + QFNF
Sbjct: 480 HDNNDIYDKAVKILETFWTEDNEEEGNDENHAPQ-SGFQFGSTNVPPGQFNF 530
>7293740 [U] KOG0166 Karyopherin (importin) alpha
Length = 543
Score = 450 bits (1158), Expect = e-126
Identities = 251/546 (45%), Positives = 344/546 (62%), Gaps = 31/546 (5%)
Query: 15 RTNFKNKGRFSADELRRRRDVQQVELRKVKRDEALAKRRNF---------NAPVGNXXXX 65
+ +KN + E+RRRR+ ++LRK KR++ L KRRN +A V +
Sbjct: 6 KQRYKNAA-LDSTEMRRRREEVGIQLRKNKREQQLFKRRNVVLEPATSSTSAGVESNTDN 64
Query: 66 XXXXXXXXXXXFYRQLQQELPA------------MLEQIHSNDLQQQLAVTVKFRQVLSR 113
Q E A M++ + S +QL T KFR++LSR
Sbjct: 65 EQQAADMHMADSSTGGQNEEAAGSGAQPSVINEEMIQMLFSGRENEQLEATQKFRKLLSR 124
Query: 114 EHRPPIDLVISTGVVPTLVQFMSENQPEMLQLEAAWALTNIASGTSEQTRVVVDAGAVPL 173
+ PPI+ VI G+VP V F+ + LQ EAAW LTNIASGTS+QT+VV++AGAVP+
Sbjct: 125 DPNPPIEEVIQKGIVPQFVTFLRNSANATLQFEAAWTLTNIASGTSQQTKVVIEAGAVPI 184
Query: 174 FIQLLYSNSVEVKEQAIWALGNVAGDSTDYRDYVLQCGAMQPILY-LFELNKTSLIRTAT 232
FI LL S +V+EQA+WALGN+AGDS RD++L G ++P+L+ L ++ ++IR A
Sbjct: 185 FIDLLSSPHDDVQEQAVWALGNIAGDSPMCRDHLLGSGILEPLLHVLSNSDRITMIRNAV 244
Query: 233 WTLSNLCRGKKPQPDWSIVSQALPTLSKLIYSMDTETLVDACWAISYLSDGPVNSIQAVV 292
WTLSNLCRGK P D++ +S LP L++L+ D + L D CWAI YLSDGP + IQAV+
Sbjct: 245 WTLSNLCRGKSPPADFAKISHGLPILARLLKYTDADVLSDTCWAIGYLSDGPNDKIQAVI 304
Query: 293 DARIPKRLVELLSHQSTLVQTPALRAVGNIVTGNDLQTQIVINCGALAALRNLLASPKES 352
DA + +RLVELL H V T ALRAVGNIVTG+D QTQ+++ AL + +LL S E+
Sbjct: 305 DAGVCRRLVELLLHPQQNVSTAALRAVGNIVTGDDQQTQVILGYNALTCISHLLHSTAET 364
Query: 353 IRKEACWTISNITAGNTEQIQAVIDANLIPPLIRLLETAEYKTKKEACWAISNASSGGLH 412
I+KE+CWTISNI AGN EQIQA+I+AN+ P L+ +++TAE+KT+KEA WAI+NA+S G H
Sbjct: 365 IKKESCWTISNIAAGNREQIQALINANIFPQLMVIMQTAEFKTRKEAAWAITNATSSGTH 424
Query: 413 KPEIIRYLVSQGCIKPLCDLLEIADNRIIEVTLDAIENILKMGEMDREVRGIAVNENADF 472
E I YLV GC+ P+CD L + D+ I++V L+A+ENILK GE + N A
Sbjct: 425 --EQIHYLVQVGCVPPMCDFLTVVDSDIVQVALNALENILKAGEKFQ----TRPNPYAIT 478
Query: 473 IEKAGGMEKIFNLQSNANEKIYEKAFKIIEKYFSDEDDVVDESMAPQTAGNTFGFGSNVN 532
IE+ GG++KI LQ++ N IY K+F IIE+YF +E++ D +AP F F +
Sbjct: 479 IEECGGLDKIEYLQAHENRDIYHKSFYIIEQYFGNEEE--DSRVAPVAGTQQFEFDPDNM 536
Query: 533 QQFNFN 538
FN
Sbjct: 537 PSTGFN 542
>At5g49310 [U] KOG0166 Karyopherin (importin) alpha
Length = 519
Score = 438 bits (1126), Expect = e-122
Identities = 253/501 (50%), Positives = 318/501 (62%), Gaps = 18/501 (3%)
Query: 12 EYRRTNFKNKGRFSADELRRRRDVQQVELRKVKRDEALAKRRNFNAPVGNXXXXXXXXXX 71
E RR +K A+E RRRR+ VE+RK KR+E L K+R +
Sbjct: 10 EIRRIRYKVS--VDAEEGRRRREDFLVEIRKSKRNENLMKKRRVKVLPPDYKLISNDPFE 67
Query: 72 XXXXXFYRQLQQELPAMLEQIHSNDLQQQLAVTVKFRQVLSREHRPPIDLVISTGVVPTL 131
E+ M+ + S+D QL T +FR VLS + PP D VI +GVVP
Sbjct: 68 SLL---------EIANMITGVFSDDPSLQLEYTTRFRVVLSFDRSPPTDNVIKSGVVPRF 118
Query: 132 VQFMSENQPEMLQLEAAWALTNIASGTSEQTRVVVDAGAVPLFIQLLYSNSVEVKEQAIW 191
V+F+ ++ LQ EAAWALTNIASG SE T+VV+D G VPLF+QLL S +V+EQAIW
Sbjct: 119 VEFLKKDDNPKLQFEAAWALTNIASGASEHTKVVIDHGVVPLFVQLLASPDDDVREQAIW 178
Query: 192 ALGNVAGDSTDYRDYVLQCGAMQPILYLFELNKT-SLIRTATWTLSNLCRGKKPQPDWSI 250
LGNVAGDS RD+VL GA P+L+ + T S++R ATWTLSN RG KP P + +
Sbjct: 179 GLGNVAGDSIQCRDFVLNSGAFIPLLHQLNNHATLSILRNATWTLSNFFRG-KPSPPFDL 237
Query: 251 VSQALPTLSKLIYSMDTETLVDACWAISYLSDGPVNSIQAVVDARIPKRLVELLSHQSTL 310
V LP L +L+YS D + L+DACWA+S LSD +IQ+V++A + RLVELL H S +
Sbjct: 238 VKHVLPVLKRLVYSDDEQVLIDACWALSNLSDASNENIQSVIEAGVVPRLVELLQHASPV 297
Query: 311 VQTPALRAVGNIVTGNDLQTQIVINCGALAALRNLLA-SPKESIRKEACWTISNITAGNT 369
V PALR +GNIV+GN QT VINCG L L +LL + IR+EACWTISNITAG
Sbjct: 298 VLVPALRCIGNIVSGNSQQTHCVINCGVLPVLADLLTQNHMRGIRREACWTISNITAGLE 357
Query: 370 EQIQAVIDANLIPPLIRLLETAEYKTKKEACWAISNASSGGLHKPEIIRYLVSQGCIKPL 429
EQIQ+VIDANLIP L+ L + AE+ KKEA WAISNAS GG P I+YLV Q CIK L
Sbjct: 358 EQIQSVIDANLIPSLVNLAQHAEFDIKKEAIWAISNASVGG--SPNQIKYLVEQNCIKAL 415
Query: 430 CDLLEIADNRIIEVTLDAIENILKMGEMDREVRGIAVNENADFIEKAGGMEKIFNLQSNA 489
CD+L D RII V+L +E IL GE+D+ +R VN + IE A G+EKI NLQ +
Sbjct: 416 CDILVCPDLRIILVSLGGLEMILIAGEVDKNLRD--VNCYSQMIEDAEGLEKIENLQHHG 473
Query: 490 NEKIYEKAFKIIEKYFSDEDD 510
N +IYEKA KI++ Y E+D
Sbjct: 474 NNEIYEKAVKILQTYGLVEED 494
>Hs4504901 [U] KOG0166 Karyopherin (importin) alpha
Length = 521
Score = 433 bits (1114), Expect = e-121
Identities = 240/521 (46%), Positives = 322/521 (61%), Gaps = 20/521 (3%)
Query: 14 RRTNFKNKGRFSADELRRRRDVQQVELRKVKRDEALAKRRNFNAPVGNXXXXXXXXXXXX 73
R NFKNKGR + +RR+R+ VELRK KRDE L KRRN
Sbjct: 11 RLKNFKNKGR-DLETMRRQRNEVVVELRKNKRDEHLLKRRNVP--------HEDICEDSD 61
Query: 74 XXXFYRQLQQELPAMLEQIHSNDLQQQLAVTVKFRQVLSREHRPPIDLVISTGVVPTLVQ 133
YR L A+++ S++ QL+ R++LS + PPID +I +G++P LV
Sbjct: 62 IDGDYRVQNTSLEAIVQNASSDNQGIQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVH 121
Query: 134 FMSENQPEMLQLEAAWALTNIASGTSEQTRVVVDAGAVPLFIQLLYSNSVEVKEQAIWAL 193
+ + LQ EAAWALTNIASGTSEQT+ VV + AVPLF++LL+S V EQA+WAL
Sbjct: 122 CLERDDNPSLQFEAAWALTNIASGTSEQTQAVVQSNAVPLFLRLLHSPHQNVCEQAVWAL 181
Query: 194 GNVAGDSTDYRDYVLQCGAMQPIL-YLFELNKTSLIRTATWTLSNLCRGKKPQPDWSIVS 252
GN+ GD RDYV+ G ++P+L ++ + +R TW + NLCR K P P +
Sbjct: 182 GNIIGDGPQCRDYVISLGVVKPLLSFISPSIPITFLRNVTWVMVNLCRHKDPPPPMETIQ 241
Query: 253 QALPTLSKLIYSMDTETLVDACWAISYLSDGPVNSIQAVVDARIPKRLVELLSHQSTLVQ 312
+ LP L LI+ D LVD WA+SYL+D IQ V+D+ I LV LLSHQ VQ
Sbjct: 242 EILPALCVLIHHTDVNILVDTVWALSYLTDAGNEQIQMVIDSGIVPHLVPLLSHQEVKVQ 301
Query: 313 TPALRAVGNIVTGNDLQTQIVINCGALAALRNLLASPKESIRKEACWTISNITAGNTEQI 372
T ALRAVGNIVTG D QTQ+V+NC AL+ LL PKE I KEA W +SNITAGN +Q+
Sbjct: 302 TAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKINKEAVWFLSNITAGNQQQV 361
Query: 373 QAVIDANLIPPLIRLLETAEYKTKKEACWAISNASSGGLHKPEIIRYLVSQGCIKPLCDL 432
QAVIDANL+P +I LL+ ++ T+KEA WAISN + G + + + YL+ Q I P C+L
Sbjct: 362 QAVIDANLVPMIIHLLDKGDFGTQKEAAWAISNLTISG--RKDQVAYLIQQNVIPPFCNL 419
Query: 433 LEIADNRIIEVTLDAIENILKMGEMDREVRGIAVNENADFIEKAGGMEKIFNLQSNANEK 492
L + D ++++V LD + NILKM E + E G + IE+ GG+EKI LQ++ NE
Sbjct: 420 LTVKDAQVVQVVLDGLSNILKMAEDEAETIG-------NLIEECGGLEKIEQLQNHENED 472
Query: 493 IYEKAFKIIEKYFSDEDDVVDESMAPQT-AGNTFGFGSNVN 532
IY+ A++II+++FS +D D S+ P+ G TFGF S+ N
Sbjct: 473 IYKLAYEIIDQFFSSDDIDEDPSLVPEAIQGGTFGFNSSAN 513
>Hs4504897 [U] KOG0166 Karyopherin (importin) alpha
Length = 529
Score = 425 bits (1092), Expect = e-118
Identities = 240/534 (44%), Positives = 330/534 (60%), Gaps = 21/534 (3%)
Query: 11 PEYRRTNFKNKGRFSADELRRRRDVQQVELRKVKRDEALAKRRNFNAPVGNXXXXXXXXX 70
P R FKNKG+ S E+RRRR VELRK K+D+ + KRRN ++ +
Sbjct: 10 PAARLHRFKNKGKDST-EMRRRRIEVNVELRKAKKDDQMLKRRNVSSFPDDATSPLQENR 68
Query: 71 XXXXXXFYRQLQQELPAMLEQIHSNDLQQQLAVTVKFRQVLSREHRPPIDLVISTGVVPT 130
+ + +++ I+S++++ QL T R++LSRE +PPID +I G++P
Sbjct: 69 NNQGT-----VNWSVDDIVKGINSSNVENQLQATQAARKLLSREKQPPIDNIIRAGLIPK 123
Query: 131 LVQFMSENQPEMLQLEAAWALTNIASGTSEQTRVVVDAGAVPLFIQLLYSNSVEVKEQAI 190
V F+ +Q E+AWALTNIASGTSEQT+ VVD GA+P FI LL S + EQA+
Sbjct: 124 FVSFLGRTDCSPIQFESAWALTNIASGTSEQTKAVVDGGAIPAFISLLASPHAHISEQAV 183
Query: 191 WALGNVAGDSTDYRDYVLQCGAMQPILYLFELNKTS-----LIRTATWTLSNLCRGKKPQ 245
WALGN+AGD + +RD V++ GA+ P+L L + S +R TWTLSNLCR K P
Sbjct: 184 WALGNIAGDGSVFRDLVIKYGAVDPLLALLAVPDMSSLACGYLRNLTWTLSNLCRNKNPA 243
Query: 246 PDWSIVSQALPTLSKLIYSMDTETLVDACWAISYLSDGPVNSIQAVVDARIPKRLVELLS 305
P V Q LPTL +L++ D E L D CWAISYL+DGP I VV + +LV+LL
Sbjct: 244 PPIDAVEQILPTLVRLLHHDDPEVLADTCWAISYLTDGPNERIGMVVKTGVVPQLVKLLG 303
Query: 306 HQSTLVQTPALRAVGNIVTGNDLQTQIVINCGALAALRNLLASPKESIRKEACWTISNIT 365
+ TPALRA+GNIVTG D QTQ+VI+ GALA +LL +PK +I+KEA WT+SNIT
Sbjct: 304 ASELPIVTPALRAIGNIVTGTDEQTQVVIDAGALAVFPSLLTNPKTNIQKEATWTMSNIT 363
Query: 366 AGNTEQIQAVIDANLIPPLIRLLETAEYKTKKEACWAISNASSGGLHKPEIIRYLVSQGC 425
AG +QIQ V++ L+P L+ +L A++KT+KEA WA++N +SGG E I YLV G
Sbjct: 364 AGRQDQIQQVVNHGLVPFLVSVLSKADFKTQKEAVWAVTNYTSGG--TVEQIVYLVHCGI 421
Query: 426 IKPLCDLLEIADNRIIEVTLDAIENILKMGEMDREVRGIAVNENADFIEKAGGMEKIFNL 485
I+PL +LL D +II V LDAI NI + E E +++ IE+ GG++KI L
Sbjct: 422 IEPLMNLLTAKDTKIILVILDAISNIFQAAEKLGETEKLSI-----MIEECGGLDKIEAL 476
Query: 486 QSNANEKIYEKAFKIIEKYFSDEDDVVDESMAPQTA--GNTFGFGSNVNQQFNF 537
Q++ NE +Y+ + +IEKYFS E++ D+++ P+T G TF FNF
Sbjct: 477 QNHENESVYKASLSLIEKYFSVEEE-EDQNVVPETTSEGYTFQVQDGAPGTFNF 529
>Hs4504899 [U] KOG0166 Karyopherin (importin) alpha
Length = 521
Score = 420 bits (1080), Expect = e-117
Identities = 238/530 (44%), Positives = 321/530 (59%), Gaps = 23/530 (4%)
Query: 13 YRRTNFKNKGRFSADELRRRRDVQQVELRKVKRDEALAKRRNFNAPVGNXXXXXXXXXXX 72
+R +FKNKGR + +RR R+ VELRK KRDE L K+RN
Sbjct: 10 HRIKSFKNKGR-DVETMRRHRNEVTVELRKNKRDEHLLKKRNVPQE--------ESLEDS 60
Query: 73 XXXXFYRQLQQELPAMLEQIHSNDLQQQLAVTVKFRQVLSREHRPPIDLVISTGVVPTLV 132
++ L A+L+ S++ QL+ R++LS + PPID +I +G++P LV
Sbjct: 61 DVDADFKAQNVTLEAILQNATSDNPVVQLSAVQAARKLLSSDQNPPIDDLIKSGILPILV 120
Query: 133 QFMSENQPEMLQLEAAWALTNIASGTSEQTRVVVDAGAVPLFIQLLYSNSVEVKEQAIWA 192
+ + + LQ EAAWALTNIASGTS QT+ VV + AVPLF++LL S V EQA+WA
Sbjct: 121 KCLERDDNPSLQFEAAWALTNIASGTSAQTQAVVQSNAVPLFLRLLRSPHQNVCEQAVWA 180
Query: 193 LGNVAGDSTDYRDYVLQCGAMQPIL-YLFELNKTSLIRTATWTLSNLCRGKKPQPDWSIV 251
LGN+ GD RDYV+ G ++P+L ++ + +R TW + NLCR K P P V
Sbjct: 181 LGNIIGDGPQCRDYVISLGVVKPLLSFISPSIPITFLRNVTWVIVNLCRNKDPPPPMETV 240
Query: 252 SQALPTLSKLIYSMDTETLVDACWAISYLSDGPVNSIQAVVDARIPKRLVELLSHQSTLV 311
+ LP L LIY D LVD WA+SYL+DG IQ V+D+ + LV LLSHQ V
Sbjct: 241 QEILPALCVLIYHTDINILVDTVWALSYLTDGGNEQIQMVIDSGVVPFLVPLLSHQEVKV 300
Query: 312 QTPALRAVGNIVTGNDLQTQIVINCGALAALRNLLASPKESIRKEACWTISNITAGNTEQ 371
QT ALRAVGNIVTG D QTQ+V+NC L+ NLL+ PKE I KEA W +SNITAGN +Q
Sbjct: 301 QTAALRAVGNIVTGTDEQTQVVLNCDVLSHFPNLLSHPKEKINKEAVWFLSNITAGNQQQ 360
Query: 372 IQAVIDANLIPPLIRLLETAEYKTKKEACWAISNASSGGLHKPEIIRYLVSQGCIKPLCD 431
+QAVIDA LIP +I L ++ T+KEA WAISN + G + + + YLV Q I P C+
Sbjct: 361 VQAVIDAGLIPMIIHQLAKGDFGTQKEAAWAISNLTISG--RKDQVEYLVQQNVIPPFCN 418
Query: 432 LLEIADNRIIEVTLDAIENILKMGEMDREVRGIAVNENADFIEKAGGMEKIFNLQSNANE 491
LL + D+++++V LD ++NIL M G + A+ IE+ GG+EKI LQ + NE
Sbjct: 419 LLSVKDSQVVQVVLDGLKNILIMA-------GDEASTIAEIIEECGGLEKIEVLQQHENE 471
Query: 492 KIYEKAFKIIEKYFSDEDDVVDESMAPQ-TAGNTFGFGSNVN---QQFNF 537
IY+ AF+II++YFS +D D + P+ T G T+ F N ++FNF
Sbjct: 472 DIYKLAFEIIDQYFSGDDIDEDPCLIPEATQGGTYNFDPTANLQTKEFNF 521
>CE20745 [U] KOG0166 Karyopherin (importin) alpha
Length = 514
Score = 405 bits (1040), Expect = e-112
Identities = 225/519 (43%), Positives = 312/519 (59%), Gaps = 25/519 (4%)
Query: 14 RRTNFKNKGRFSADELRRRRDVQQVELRKVKRDEALAKRRNFNAPVGNXXXXXXXXXXXX 73
R+ +KN + + +R +V V +RK KR+EA++KRRN N + +
Sbjct: 5 RQAYYKNNAKEQIGKEKRNEEV--VSIRKDKREEAISKRRNINTQIEDDSETSTTPPGPF 62
Query: 74 XXXFYRQLQQELPAMLEQIHSNDLQQQLAVTVKFRQVLSREHRPPIDLVISTGVVPTLVQ 133
R + S+D +QL + R++LS + PPID +I +G++P LVQ
Sbjct: 63 DANLLR-------LTVAAAQSSDPAEQLTAVQQARKMLSTDRNPPIDDLIGSGILPVLVQ 115
Query: 134 FMSENQPEMLQLEAAWALTNIASGTSEQTRVVVDAGAVPLFIQLLYSNSVEVKEQAIWAL 193
+S P LQ EAAWALTNIASGTSEQT+ VV+AGAVPLF+QLL ++ V EQ++WAL
Sbjct: 116 CLSSTDPN-LQFEAAWALTNIASGTSEQTQAVVNAGAVPLFLQLLSCGNLNVCEQSVWAL 174
Query: 194 GNVAGDSTDYRDYVLQCGAMQPILYLFELN-KTSLIRTATWTLSNLCRGKKPQPDWSIVS 252
GN+ GD +RDY L+ G +QP+L +R TW + NLCR K P P ++V
Sbjct: 175 GNIIGDGPHFRDYCLELGILQPLLQFINPEIPIGFLRNVTWVIVNLCRCKDPAPSPAVVR 234
Query: 253 QALPTLSKLIYSMDTETLVDACWAISYLSDGPVNSIQAVVDARIPKRLVELLSHQSTLVQ 312
LP LS LI+ DT L+D WA+SYL+DG IQ V++A++ LV LL H VQ
Sbjct: 235 TILPALSLLIHHQDTNILIDTVWALSYLTDGGNEHIQMVIEAQVVTHLVPLLGHVDVKVQ 294
Query: 313 TPALRAVGNIVTGNDLQTQIVINCGALAALRNLLASPKESIRKEACWTISNITAGNTEQI 372
T ALRAVGNIVTG D QTQ+V++ G L + LLA KE I KEA W +SNITAGN +Q+
Sbjct: 295 TAALRAVGNIVTGTDEQTQLVLDSGVLRFMPGLLAHYKEKINKEAVWFVSNITAGNQQQV 354
Query: 373 QAVIDANLIPPLIRLLETAEYKTKKEACWAISNASSGGLHKPEIIRYLVSQGCIKPLCDL 432
Q V DA ++P +I LL+ ++ T+KEA WAISN + G +P + +V G ++P C +
Sbjct: 355 QDVFDAGIMPMIIHLLDRGDFPTQKEAAWAISNVTISG--RPNQVEQMVKLGVLRPFCAM 412
Query: 433 LEIADNRIIEVTLDAIENILKMGEMDREVRGIAVNENADFIEKAGGMEKIFNLQSNANEK 492
L D++II+V LD I NILKM G A + IE+ GG++KI NLQ++ NE
Sbjct: 413 LSCTDSQIIQVVLDGINNILKMA-------GEAAEQVTSEIEECGGLDKIENLQNHENED 465
Query: 493 IYEKAFKIIEKYFSDEDDVVDESMAPQTAGNTFGFGSNV 531
IY+ AF+II+ +FS +D+ + A +A FG +V
Sbjct: 466 IYKLAFEIIDNFFSSDDETGNVEGAQSSA-----FGGDV 499
>7299211 [U] KOG0166 Karyopherin (importin) alpha
Length = 514
Score = 401 bits (1031), Expect = e-111
Identities = 232/529 (43%), Positives = 323/529 (60%), Gaps = 27/529 (5%)
Query: 14 RRTNFKNKGRFSADELRRRRDVQQVELRKVKRDEALAKRRNFNAPVGNXXXXXXXXXXXX 73
R NFKNKG+ DE+RRRR+ VELRK KR+E + KRRN V N
Sbjct: 8 RLQNFKNKGK-DQDEMRRRRNEVTVELRKNKREETILKRRN----VPNLDSNTDEEEQLS 62
Query: 74 XXXFYRQLQQELPAMLEQIHSNDLQQQLAVTVKFRQVLSREHRPPIDLVISTGVVPTLVQ 133
++L + + +QQLA R++LS + PPI+ +I + ++P LV+
Sbjct: 63 SSIDLKKLAKAAADATKP------EQQLAAVQAARKLLSSDKNPPINDLIQSDILPILVE 116
Query: 134 FMSENQPEMLQLEAAWALTNIASGTSEQTRVVVDAGAVPLFIQLLYSNSVEVKEQAIWAL 193
+ ++ MLQ EAAWALTNIASGTS QT VV AGAVPLF+QLL S + V EQA+WAL
Sbjct: 117 CLKQHNHTMLQFEAAWALTNIASGTSAQTNEVVAAGAVPLFLQLLNSPAPNVCEQAVWAL 176
Query: 194 GNVAGDSTDYRDYVLQCGAMQPILYLFELN-KTSLIRTATWTLSNLCRGKKPQPDWSIVS 252
GN+ GD RD+V++ G +QP+L + + + +R TW + NLCR K P P + +
Sbjct: 177 GNIIGDGPLLRDFVIKHGVVQPLLSFIKPDIPITFLRNVTWVIVNLCRNKDPAPPTATIH 236
Query: 253 QALPTLSKLIYSMDTETLVDACWAISYLSDGPVNSIQAVVDARIPKRLVELLSHQSTLVQ 312
+ LP L+ LI+ DT LVD WAISYL+DG + IQ V+++ + +L+ LL + VQ
Sbjct: 237 EILPALNVLIHHTDTNILVDTVWAISYLTDGGNDQIQMVIESGVVPKLIPLLGNSEVKVQ 296
Query: 313 TPALRAVGNIVTGNDLQTQIVINCGALAALRNLLASPKESIRKEACWTISNITAGNTEQI 372
T ALRAVGNIVTG+D QTQ+V+N AL+ LL+ PKE IRKEA W +SNITAGN Q+
Sbjct: 297 TAALRAVGNIVTGSDEQTQVVLNYDALSYFPGLLSHPKEKIRKEAVWFLSNITAGNQSQV 356
Query: 373 QAVIDANLIPPLIRLLETAEYKTKKEACWAISNASSGGLHKPEIIRYLVSQGCIKPLCDL 432
QAVI+ L+P +I L E++T+KEA WAISN + G E + L+ +G I P CDL
Sbjct: 357 QAVINVGLLPKIIENLSKGEFQTQKEAAWAISNLTISG--NREQVFTLIKEGVIPPFCDL 414
Query: 433 LEIADNRIIEVTLDAIENILKMGEMDREVRGIAVNENADFIEKAGGMEKIFNLQSNANEK 492
L D ++I V LD + N+LK+ D V + A+ IE+ G+ KI LQS+ N +
Sbjct: 415 LSCQDTQVINVVLDGLNNMLKVA--DSHVEAV-----ANCIEECEGLAKIERLQSHENVE 467
Query: 493 IYEKAFKIIEKYFSDEDDVVDESMAPQTAGNTFGFGSNVNQ----QFNF 537
IY+ A++II++YF+DE + +MAP + G + F + ++ FNF
Sbjct: 468 IYKLAYEIIDQYFTDEGE--QTNMAPTSDGAQYNFDPHADRLTMNSFNF 514
>At3g05720 [U] KOG0166 Karyopherin (importin) alpha
Length = 528
Score = 386 bits (992), Expect = e-107
Identities = 234/498 (46%), Positives = 308/498 (60%), Gaps = 36/498 (7%)
Query: 30 RRRRDVQQVELRKVKRDEALAKRRNFNAPVGNXXXXXXXXXXXXXXXFYRQLQQELPAML 89
RRRR+ VE+RK KR+E+L K+R P L Q+L +
Sbjct: 24 RRRREDDMVEIRKAKREESLLKKRREALPHSPSADS---------------LDQKL---I 65
Query: 90 EQIHSNDLQQQLAVTVKFRQVLSRE-HRPPIDLVISTGVVPTLVQFMSENQPEMLQLEAA 148
I S++ + T + R +L E ++ VI G+VP V+F++ + LQ EAA
Sbjct: 66 SCIWSDERDLLIEATTQIRTLLCGEMFNVRVEEVIQAGLVPRFVEFLTWDDSPQLQFEAA 125
Query: 149 WALTNIASGTSEQTRVVVDAGAVPLFIQLLYSNSVEVKEQAIWALGNVAGDSTDYRDYVL 208
WALTNIASGTSE T VV+D GAV + ++LL S V+EQ +WALGN++GDS RD VL
Sbjct: 126 WALTNIASGTSENTEVVIDHGAVAILVRLLNSPYDVVREQVVWALGNISGDSPRCRDIVL 185
Query: 209 QCGAMQPILYLFELN---KTSLIRTATWTLSNLCRGKKPQPDWSIVSQALPTLSKLIYSM 265
A+ +L +LN K S++ A WTLSNLCRGK PQP + VS ALP L++LI
Sbjct: 186 GHAALPSLL--LQLNHGAKLSMLVNAAWTLSNLCRGK-PQPPFDQVSAALPALAQLIRLD 242
Query: 266 DTETLVDACWAISYLSDGPVNSIQAVVDARIPKRLVELLSHQSTLVQTPALRAVGNIVTG 325
D E L CWA+ YLSDG IQAV++A + RL+ L H+S V TPALR +GNIVTG
Sbjct: 243 DKELLAYTCWALVYLSDGSNEKIQAVIEANVCARLIGLSIHRSPSVITPALRTIGNIVTG 302
Query: 326 NDLQTQIVINCGALAALRNLL-ASPKESIRKEACWTISNITAGNTEQIQAVIDANLIPPL 384
ND QTQ +I+ AL L NLL S ++IRKEACWT+SNITAG QIQAV DA++ P L
Sbjct: 303 NDSQTQHIIDLQALPCLVNLLRGSYNKTIRKEACWTVSNITAGCQSQIQAVFDADICPAL 362
Query: 385 IRLLETAEYKTKKEACWAISNASSGGLHKPEIIRYLVSQGCIKPLCDLLEIADNRIIEVT 444
+ LL+ +E KKEA WAI NA +GG +K I +LV Q CIKPLCDLL +D +++ V
Sbjct: 363 VNLLQNSEGDVKKEAAWAICNAIAGGSYKQ--IMFLVKQECIKPLCDLLTCSDTQLVMVC 420
Query: 445 LDAIENILKMGEM--DREVRGI------AVNENADFIEKAGGMEKIFNLQSNANEKIYEK 496
L+A++ ILK+GE+ R GI VN +A IE+A G+EKI LQS+ N IYE
Sbjct: 421 LEALKKILKVGEVFSSRHAEGIYQCPQTNVNPHAQLIEEAEGLEKIEGLQSHENNDIYET 480
Query: 497 AFKIIEKYFSDEDDVVDE 514
A KI+E Y+ +E++ D+
Sbjct: 481 AVKILETYWMEEEEEEDQ 498
>7297600 [U] KOG0166 Karyopherin (importin) alpha
Length = 522
Score = 373 bits (958), Expect = e-103
Identities = 211/525 (40%), Positives = 302/525 (57%), Gaps = 18/525 (3%)
Query: 7 SKFVPEYRRTNFKNKGRFSADELRRRRDVQQVELRKVKRDEALAKRRNFNAPVGNXXXXX 66
SK R+ ++K + D RR +V +ELRK K+++ + KRRN N
Sbjct: 2 SKADSNSRQGSYKANSINTQDSRMRRHEVT-IELRKSKKEDQMFKRRNIN--------DE 52
Query: 67 XXXXXXXXXXFYRQLQQELPAMLEQIHSNDLQQQLAVTVKFRQVLSREHRPPIDLVISTG 126
+Q + ++ ++S D ++Q R++LSRE PPIDL+I G
Sbjct: 53 DLTSPLKELNGQSPVQLSVDEIVAAMNSEDQERQFLGMQSARKMLSRERNPPIDLMIGHG 112
Query: 127 VVPTLVQFMSENQPEMLQLEAAWALTNIASGTSEQTRVVVDAGAVPLFIQLLYSNSVEVK 186
+VP ++F+ MLQ EAAWALTNIASGTS+QTR V++ AVP F+ LL S S+ +
Sbjct: 113 IVPICIRFLQNTNNSMLQFEAAWALTNIASGTSDQTRCVIEHNAVPHFVALLQSKSMNLA 172
Query: 187 EQAIWALGNVAGDSTDYRDYVLQCGAMQPILYLFELNKT--SLIRTATWTLSNLCRGKKP 244
EQA+WALGN+AGD RD V+ + IL L N+T S +R W +SNLCR K P
Sbjct: 173 EQAVWALGNIAGDGAAARDIVIHHNVIDGILPLIN-NETPLSFLRNIVWLMSNLCRNKNP 231
Query: 245 QPDWSIVSQALPTLSKLIYSMDTETLVDACWAISYLSDGPVNSIQAVVDARIPKRLVELL 304
P + V + LP LS+L+ S D + L DACWA+SY++D IQAVVD+ RLV+LL
Sbjct: 232 SPPFDQVKRLLPVLSQLLLSQDIQVLADACWALSYVTDDDNTKIQAVVDSDAVPRLVKLL 291
Query: 305 SHQSTLVQTPALRAVGNIVTGNDLQTQIVINCGALAALRNLLASPKESIRKEACWTISNI 364
+ PALR+VGNIVTG D QT +VI G L L LL K +I KEA WT+SNI
Sbjct: 292 QMDEPSIIVPALRSVGNIVTGTDQQTDVVIASGGLPRLGLLLQHNKSNIVKEAAWTVSNI 351
Query: 365 TAGNTEQIQAVIDANLIPPLIRLLETAEYKTKKEACWAISNASSGGLHKPEIIRYLVSQG 424
TAGN +QIQAVI A + L +LE ++K +KEA WA++N ++ G + +I+ +
Sbjct: 352 TAGNQKQIQAVIQAGIFQQLRTVLEKGDFKAQKEAAWAVTNTTTSGTPE-QIVDLIEKYK 410
Query: 425 CIKPLCDLLEIADNRIIEVTLDAIENILKMGEMDREVRGIAVNENADFIEKAGGMEKIFN 484
+KP DLL+ D R I+V + N+ + E + + +E+ GG++K+
Sbjct: 411 ILKPFIDLLDTKDPRTIKVVQTGLSNLFALAEKLGGTENLCL-----MVEEMGGLDKLET 465
Query: 485 LQSNANEKIYEKAFKIIEKYFSDEDDVVDESMAPQTAGNTFGFGS 529
LQ + NE++Y+KA+ II+ YFS+ DD ++ +APQ F +
Sbjct: 466 LQQHENEEVYKKAYAIIDTYFSNGDDEAEQELAPQEVNGALEFNA 510
>At5g52000 [U] KOG0166 Karyopherin (importin) alpha
Length = 441
Score = 329 bits (844), Expect = 6e-90
Identities = 197/425 (46%), Positives = 260/425 (60%), Gaps = 15/425 (3%)
Query: 88 MLEQIHSNDLQQQLAVTVKFRQVLSREHRPPIDLVISTGVVPTLVQFMSENQPEMLQLEA 147
+++ + S+D QL K R++ S+ I VI +GVVP LVQ + LQ E
Sbjct: 14 IIDGLWSDDPPLQLESVTKIRRITSQRD---ISCVIRSGVVPRLVQLLKNQVFPKLQYEV 70
Query: 148 AWALTNIASGTSEQTRVVVDAGAVPLFIQLLYSNSVEVKEQAIWALGNVAGDSTDYRDYV 207
AWALTNIA + VVV+ AVP+ IQL+ S V+EQAIW L NVAG S YRD+V
Sbjct: 71 AWALTNIAV---DNPGVVVNNNAVPVLIQLIASPKDYVREQAIWTLSNVAGHSIHYRDFV 127
Query: 208 LQCGAMQPILYLFELNKTSLIRTATWTLSNLCRGKKPQPDWSIVSQALPTLSKLIYSMDT 267
L G + P+L L L K + +R ATW L NLCRGK P P + V ALP L L++S D
Sbjct: 128 LNSGVLMPLLRL--LYKDTTLRIATWALRNLCRGK-PHPAFDQVKPALPALEILLHSHDE 184
Query: 268 ETLVDACWAISYLSDGPVNSIQAVVDARIPKRLVELLSHQSTLVQTPALRAVGNIVTGND 327
+ L +AC A+ +LS+G + IQ+V++A +LV++L S +V PAL +G + GN
Sbjct: 185 DVLKNACMALCHLSEGSEDGIQSVIEAGFVPKLVQILQLPSPVVLVPALLTIGAMTAGNH 244
Query: 328 LQTQIVINCGALAALRNLLASPKES-IRKEACWTISNITAGNTEQIQAVIDANLIPPLIR 386
QTQ VIN GAL + N+L E+ I+K ACW ISNITAG EQIQ+VIDANLIP L+
Sbjct: 245 QQTQCVINSGALPIISNMLTRNHENKIKKCACWVISNITAGTKEQIQSVIDANLIPILVN 304
Query: 387 LLETAEYKTKKEACWAISNASSGGLHKPEIIRYLVSQGCIKPLCDLLEIADNR-IIEVTL 445
L + ++ KKEA WAISN + G H + I+Y+ Q CIK LCD+L +D R I L
Sbjct: 305 LAQDTDFYMKKEAVWAISNMALNGSH--DQIKYMAEQSCIKQLCDILVYSDERTTILKCL 362
Query: 446 DAIENILKMGEMDREVRGIAVNENADFIEKAGGMEKIFNLQSNANEKIYEKAFKIIEKYF 505
D +EN+LK GE ++ VN IE A G+EKI LQ N N+ IYEKA+KI+ +
Sbjct: 363 DGLENMLKAGEAEKNSED--VNPYCLLIEDAEGLEKISKLQMNKNDDIYEKAYKILVTNW 420
Query: 506 SDEDD 510
+EDD
Sbjct: 421 FEEDD 425
>CE09675 [U] KOG0166 Karyopherin (importin) alpha
Length = 531
Score = 290 bits (743), Expect = 3e-78
Identities = 176/496 (35%), Positives = 270/496 (53%), Gaps = 16/496 (3%)
Query: 27 DELRRRRDVQQVELRKVKRDEALAKRRNF---NAPVGNXXXXXXXXXXXXXXXFYRQLQQ 83
+ELRRRR VE+RK K + + KRRN + + R
Sbjct: 32 EELRRRRTECSVEIRKQKGADMMMKRRNIVDVDEGGNSESELEEPEKISHQQSSTRLSND 91
Query: 84 ELPAMLEQIHSNDLQQQLAVTVKFRQVLSREHRPPIDLVISTGVVPTLVQFMSENQPEML 143
E+ A+L S D + R+ LS+ PPID VI G++ LVQ +S E +
Sbjct: 92 EIRAILSNNPSED--DMVRCFESLRKSLSKTKNPPIDEVIHCGLLQALVQALSVEN-ERV 148
Query: 144 QLEAAWALTNIASGTSEQTRVVVDAGAVPLFIQLLYSNSVEVKEQAIWALGNVAGDSTDY 203
Q EAAWALTNI SG++EQT V+AG I L S ++ EQA+WA+ N+AGDS+
Sbjct: 149 QYEAAWALTNIVSGSTEQTIAAVEAGVTIPLIHLSVHQSAQISEQALWAVANIAGDSSQL 208
Query: 204 RDYVLQCGAMQPILYLFELNK---TSLIRTATWTLSNLCRGKKPQPDWSIVSQALPTLSK 260
RDYV++C ++ +++L E S +RT W SN+CR K P ++ L K
Sbjct: 209 RDYVIKCHGVEALMHLMEKVDQLGDSHVRTIAWAFSNMCRHKNPHAPLEVLRVLSKGLVK 268
Query: 261 LIYSMDTETLVDACWAISYLSDGPVNSIQAVVDARIPKRLVELLSHQSTLVQTPALRAVG 320
L+ D + DACWA+SYL+DGP I+ ++ + +V LV PALR +G
Sbjct: 269 LVQHTDRQVRQDACWAVSYLTDGPDEQIELARESGVLPHVVAFFKEAENLV-APALRTLG 327
Query: 321 NIVTGNDLQTQIVINCGALAALRNLLASPK-ESIRKEACWTISNITAGNTEQIQAVIDAN 379
N+ TGND TQ VI+ G+L + L+ + SI KE CW +SNI AG +QIQAV+DAN
Sbjct: 328 NVATGNDSLTQAVIDLGSLDEILPLMEKTRSSSIVKECCWLVSNIIAGTQKQIQAVLDAN 387
Query: 380 LIPPLIRLLETAEYKTKKEACWAISNASSGGLHKPEIIRYLVSQGCIKPLCDLLEIADNR 439
L+P LI +L++ ++K + EA WA+SN + GG ++ + ++ + LC L +
Sbjct: 388 LLPVLINVLKSGDHKCQFEASWALSNLAQGGTNRQVVA--MLEDNVVPALCQALLQTNTD 445
Query: 440 IIEVTLDAIENILKMGEMDREVRGIAVNENADFIEKAGGMEKIFNLQSNANEKIYEKAFK 499
++ TL+ + ++ + + V+ D +E+ GG++ + LQ + +E+IY +A++
Sbjct: 446 MLNNTLETLYTLMLTVQNGYPHK---VDILHDQVEENGGLDSLERLQESQSEQIYTQAYR 502
Query: 500 IIEKYFSDEDDVVDES 515
II ++F+D+D ES
Sbjct: 503 IITQFFTDDDAGEKES 518
>ECU11g1760 [U] KOG0166 Karyopherin (importin) alpha
Length = 537
Score = 251 bits (642), Expect = 1e-66
Identities = 182/550 (33%), Positives = 283/550 (51%), Gaps = 87/550 (15%)
Query: 25 SADELRRRRDVQQVELRKVKRDEALAKRRNFNAPVGNXXXXXXXXXXXXXXXFYRQLQQE 84
+ + R+ R+ QQVELR+ K++E L K+RN + +
Sbjct: 11 TTENRRKMREEQQVELRQQKKEELLNKKRNLSVSAS-------------------AISNF 51
Query: 85 LPAMLEQIHSNDLQQQLAVTVKFRQVLSREHRPPIDLVISTGVVPTLVQFMS-------- 136
+P M E++ SNDL+Q +FR +LS E PPI VI +G VP ++ M
Sbjct: 52 IP-MKEKLFSNDLEQAHQGVYEFRSLLSVEDSPPIQPVIDSGCVPRFIELMDISFLTSSG 110
Query: 137 ------------ENQPEM---------LQLEAAWALTNIASGTSEQTRVVVDAGAVPLFI 175
+ PE +++EAAW +TNI+SGT++QT+VV+D GAVPL I
Sbjct: 111 MVMGGIPVSNIQRDMPEFSVAMDIINKIRVEAAWVITNISSGTTQQTKVVIDCGAVPLLI 170
Query: 176 QLLYSNSVEVKEQAIWALGNVAGDSTDYRDYVLQCGAMQPIL-YLFELNKTS----LIRT 230
Q+L + V +Q++WALGN+AGDS RD +L+ GA+ +L L +L++++ ++R
Sbjct: 171 QMLLDTNDAVLDQSVWALGNIAGDSEGMRDIILETGALDTVLGLLLKLHESAIHIKIVRN 230
Query: 231 ATWTLSNLCRGKKPQPDWSIVSQALPTLSKLIYSMDTETLVDACWAISYLSDGPVNSIQA 290
TW LSNL RG+ P P + ++L L KLI D E + DA WA+SY+ D +
Sbjct: 231 LTWLLSNLNRGRNPPPSEQNMRKSLEILFKLINIRDPEVVSDAYWALSYIVDVSMECSDI 290
Query: 291 VVDARIPKR---LVELLSHQSTLVQ-------------TPALRAVGNIVTGNDLQTQIVI 334
V+++ R L+E L+++ + +P +R +GNIVTG+D QT +I
Sbjct: 291 VLNSGTMGRTHSLLEALTNRLVGMSYSAEDAKICLCAISPIIRMIGNIVTGSDDQTSALI 350
Query: 335 NCGALAALRNL---LASPKE-SIRKEACWTISNITAGNTEQIQAVIDANLIPPLIRLLET 390
G L R + L + K+ +RKE CWT+SNITAG E +AV+D +L P LI + +
Sbjct: 351 RMGFLKFFRPIFYRLENKKQPRLRKEICWTLSNITAGTVEHAKAVMDMDLAPLLIDSMSS 410
Query: 391 AEYKTKKEACWAI-------SNASSGGLHKPEIIRYLVSQGCIKPLCDLLEIADNRIIEV 443
E +KEACWA+ +N S K E ++ L+ G I L L++ N + E+
Sbjct: 411 YELFIRKEACWAVLNLMYHCNNLPSSSDIKFEWLKILMDNGFIDALESYLDVVPN-VPEM 469
Query: 444 ---TLDAIENILKMGEMDREVRGIAVNENADFIEKAGGMEKIFNLQSNANEKIYEKAFKI 500
LD L G+ E+R N + + +A ++ I LQ + + + +KA+ I
Sbjct: 470 QCQILDCFRYALNGGK-QWELR-YGKNPIYEKMVEADIVDAIEGLQDSVDRTVSDKAYSI 527
Query: 501 IEKYFSDEDD 510
I +F D+
Sbjct: 528 IVDFFDGVDN 537
>At5g03070 [U] KOG0166 Karyopherin (importin) alpha
Length = 483
Score = 187 bits (476), Expect = 3e-47
Identities = 130/442 (29%), Positives = 219/442 (49%), Gaps = 51/442 (11%)
Query: 83 QELPAMLEQIHSNDLQQQLAVTVKFRQVLSREHRPPIDLVISTGVVPTLVQFMSENQPEM 142
+EL + ++ +Q+++ + R++LS+ PP++ + G +P LVQ +S P+
Sbjct: 83 EELKSAVQYQGKGAMQKRVTALRELRRLLSKSEFPPVEAALRAGAIPLLVQCLSFGSPDE 142
Query: 143 LQLEAAWALTNIASGTSEQTRVVVDAGAVPLFI-QLLYSNSVEVKEQAIWALGNVAGDST 201
LE+AW LTNIA+G E+T+ ++ A+PL I L +S V EQ WA+GNVAG+
Sbjct: 143 QLLESAWCLTNIAAGKPEETKALLP--ALPLLIAHLGEKSSAPVAEQCAWAIGNVAGEGE 200
Query: 202 DYRDYVLQCGAMQPILYLFELNKTSLIRTATWTLSNLCRGKKPQPDWSIV--SQALPTLS 259
D R+ +L GA+ P+ + +K S +RTA W LSNL +G + + +V L +
Sbjct: 201 DLRNVLLSQGALPPLARMIFPDKGSTVRTAAWALSNLIKGPESKAAAQLVKIDGILDAIL 260
Query: 260 KLIYSMDTETLVDACWAISYLSDGPVNSIQAVVDARIPKRLVELLSHQSTLVQTPALRAV 319
+ + D ET + W I YLS + ++ I + L++ L+ S+L
Sbjct: 261 RHLKKTDEETATEIAWIIVYLSALSDIATSMLLKGGILQLLIDRLATSSSL--------- 311
Query: 320 GNIVTGNDLQTQIVINCGALAALRNLLASPKESIRKEACWTISNITAGNTEQIQAVIDAN 379
Q++I C L S ++KEA W +SNI AG+ E + +
Sbjct: 312 -----------QLLIPC---------LRSEHRVLKKEAAWVLSNIAAGSIEHKRMIHSTE 351
Query: 380 LIPPLIRLLETAEYKTKKEACWAISN---ASSGGLHKPEIIR----YLVSQGCIKPLCDL 432
++P L+R+L T+ + +KE + + N S+ G KP II+ +VS GC++ +L
Sbjct: 352 VMPLLLRILSTSPFDIRKEVAYVLGNLCVESAEGDRKPRIIQEHLVSIVSGGCLRGFIEL 411
Query: 433 LEIADNRIIEVTLDAIENILKMGEMDREVRGIAVNENADFIEKAGGMEKIFNLQSNANEK 492
+ D + L IE +L RG+ E +E G++ + Q + NE+
Sbjct: 412 VRSPDIEAARLGLQFIELVL---------RGMPNGEGPKLVEGEDGIDAMERFQFHENEE 462
Query: 493 IYEKAFKIIEKYFSDEDDVVDE 514
+ A +++KYF ED +DE
Sbjct: 463 LRVMANSLVDKYFG-EDYGIDE 483
>7295403 [U] KOG0166 Karyopherin (importin) alpha
Length = 442
Score = 178 bits (451), Expect = 2e-44
Identities = 125/422 (29%), Positives = 216/422 (50%), Gaps = 17/422 (4%)
Query: 89 LEQIHSNDLQQQLAV--TVKFRQVLSREHRPPIDLVISTGVVPTLVQFMSENQPEMLQLE 146
LE+ +LQ++L + + ++ S E P ++ ++ + + LV+ + ++ +
Sbjct: 23 LEKAKKAELQKELTIYNALTKCKLTSSEVVPDVNKLLKSNTIGNLVESLGHGNKNKIRAD 82
Query: 147 AAWALTNIASGTSEQTRVVVDAGAVPLFIQLLYSNSVEVKEQAIWALGNVAGDSTDYRDY 206
AA AL +IASG+SE + ++ AGAVP I+LL S EV E+ I +LGN+ + + RDY
Sbjct: 83 AADALAHIASGSSEHSNLIAKAGAVPRLIRLLQSPDPEVCEKGILSLGNLLHFAPNLRDY 142
Query: 207 VLQCGAMQPILYLFELNKTS--LIRTATWTLSNLCRGKKPQPDWSIVSQALPTLSKLIYS 264
+++ G MQ ++ + + T ++ TW L LC +P P ++ + L+ ++Y+
Sbjct: 143 IIRHGLMQKLMSIIQDKSTCTLMLSHVTWVLRKLCISSQPSPP-DNAAEIIQALNIVLYN 201
Query: 265 MDTETLVDACWAISYLSDGPVNSIQAVVDARIPKRLVELLSHQSTLVQTPALRAVGNIVT 324
+ L DA A+ L+ G +IQ ++D + R++ LL H + VQ AL+A+ NI T
Sbjct: 202 PEANVLEDALMAVRNLAHGN-ETIQMLLDFEVVPRIIYLLEHPNVTVQNAALQALINIAT 260
Query: 325 GNDLQTQIVINCGALAALRNLLASPKESIRKEACWTISNITAGNTEQIQAVIDANLIPPL 384
G++ Q Q ++N L L L+++ IR + + NI GN Q A+++A L+ +
Sbjct: 261 GSEEQIQELLNNNLLPHLSALMSNSDPDIRCQVLKLLLNIADGNIFQRHAIMNAGLLHKI 320
Query: 385 IRLLETAEYKTKKEACWAISNASSGGLHKPEIIRYLVSQGCIKPLCDLLEIADNRIIEVT 444
+ L+ K A I+ + ++ YL+ QG I C+LL + I+
Sbjct: 321 LECLKADAISLKSAAALTITTLAID--KDKNLLCYLMRQGVIPEFCNLLFCQERDILSNV 378
Query: 445 LDAIENILKMG-EMDREVRGIAVNENADFIEKAGGMEKIFNLQSNANEKIYEKAFKIIEK 503
LD + +L + EV GI IE +G + I LQS+ +E+I A KII
Sbjct: 379 LDILSTMLDVDPSFSAEVSGI--------IEWSGALNNIRMLQSSEHEEIAAVARKIIGN 430
Query: 504 YF 505
YF
Sbjct: 431 YF 432
>Hs17443779 [U] KOG0166 Karyopherin (importin) alpha
Length = 372
Score = 166 bits (421), Expect = 6e-41
Identities = 128/413 (30%), Positives = 184/413 (43%), Gaps = 84/413 (20%)
Query: 29 LRRRRDVQQVELRKVKRDEALAKRRNFNAPVGNXXXXXXXXXXXXXXXFYRQLQQELPAM 88
+R RR V+LRK KR++ + KRRN + + + +
Sbjct: 1 MRCRRIEVNVKLRKAKRNDQMLKRRN-----ASSFPDVAASPLEKNRKNQGTVNWSVDDI 55
Query: 89 LEQIHSNDLQQQLAVTVKFRQVLSREHRPPIDLVISTGVVPTLVQFMSENQPEMLQLEAA 148
++ +SN+++ QL T ++LSRE +PPI +I
Sbjct: 56 VKGTNSNNMESQLQATQAAMKLLSREKQPPIGNII------------------------- 90
Query: 149 WALTNIASGTSEQTRVVVDAGAVPLFIQLLYSNSVEVKEQAIWALGNVAGDSTDYRDYVL 208
WA S + EQA+WALGN+AGD +RD V+
Sbjct: 91 WAA----------------------------SPHAHISEQAVWALGNIAGDGLVFRDLVI 122
Query: 209 QCGAMQPILYLFELNKTSLIRTA-----TWTLSNLCRGKKPQPDWSIVSQALPTLSKLIY 263
+ GA+ P+L L + S + TWTLS LC K P P V Q L TL L++
Sbjct: 123 KYGAVDPLLALLAVPDMSSLVCGYLCHLTWTLSILCCYKNPAPQLDAVEQILSTLVWLLH 182
Query: 264 SMDTETLVDACWAISYLSDGPVNSIQAVVDARIPKRLVELLSHQSTLVQTPALRAVGNIV 323
D E L D+CWAISYL+DGP + + +LV+LL TPALR +GNIV
Sbjct: 183 HDDPEVLADSCWAISYLTDGPNKRTDMFLKIGVLPQLVKLLGASELPTVTPALRPIGNIV 242
Query: 324 TGNDLQTQIVINCGALAALRNLLASPKESIRKEACWTISNITAGNTEQIQAVIDA--NLI 381
TG D +TQ+VI+ GALA NLL + K + +KE +T+ I ++DA N+
Sbjct: 243 TGTDEETQVVIDAGALAVFPNLLINSKTNFQKE-----------DTKVILVILDAISNIF 291
Query: 382 PPLIRLLETAEYKTKKEACWAISNASSGGLHKPEIIRYLVSQGCIKPLCDLLE 434
+L ET + E C GGL K E ++ ++ K L L+E
Sbjct: 292 QAAEKLGETEKLSIMIEEC--------GGLDKIEALQNHENESVYKALLSLIE 336
>Hs17464994 [U] KOG0166 Karyopherin (importin) alpha
Length = 438
Score = 154 bits (389), Expect = 3e-37
Identities = 104/292 (35%), Positives = 152/292 (51%), Gaps = 54/292 (18%)
Query: 234 TLSNLCRGKKPQPDWSIVSQALPTLSKLIYSMDTETLVDACWAISYLSDGPVNSIQAVVD 293
TL+NLC K P V + LPTL L++ + E LVD CWA+SYL+DG I VV
Sbjct: 187 TLTNLCCNKNPAAPLGAVEKILPTLVWLLHHNNPEVLVDTCWAVSYLTDGLNEWIDMVVK 246
Query: 294 ARIPKRLVELLSHQSTLVQTPALRAVGNIVTGNDLQTQIVINCGALAALRNLLASPKESI 353
+ +LV+LL + TPALRA+GNIV
Sbjct: 247 TEVVTQLVKLLGVSELPIVTPALRAIGNIV------------------------------ 276
Query: 354 RKEACWTISNITAGNTEQIQAVIDANLIPPLIRLLETAEYKTKKEACWAISNASSGGLHK 413
TAG +QIQ ++ L+ +L A++KT+KEA A++N++S G+
Sbjct: 277 -----------TAGLQDQIQQAMNHRLVS----VLSKADFKTQKEAVLAVTNSTSSGI-- 319
Query: 414 PEIIRYLVSQGCIKPLCDLLEIADNRIIEVTLDAIENILKMGEMDREVRGIAVNENADFI 473
E I YLV G I+PL +LL + D +II VTLDAI NI + E E +++ I
Sbjct: 320 VEQIVYLVHCGIIEPLMNLLTVKDTKIILVTLDAISNIFQAVEKLGETEKLSI-----MI 374
Query: 474 EKAGGMEKIFNLQSNANEKIYEKAFKIIEKYFSDEDDVVDESMAPQTAGNTF 525
E+ GG++KI LQ++AN+ IY+ + +I KYFS E++ ++ P T ++
Sbjct: 375 EECGGLDKIEALQNHANQFIYKASLSLIGKYFSVEEE--EDQNVPDTTSESY 424
>Hs22051967_1 [U] KOG0166 Karyopherin (importin) alpha
Length = 453
Score = 132 bits (331), Expect = 2e-30
Identities = 103/321 (32%), Positives = 155/321 (48%), Gaps = 52/321 (16%)
Query: 189 AIWALGNVAGDSTDYRDYVLQCGAMQPILYLFELN-KTSLIRTATWTLSNLCRGKKPQPD 247
A+WALGN+ D ++RD V+ A+ + L + +R TWT SNLCR K P P
Sbjct: 59 AMWALGNIPSDGLEFRDNVISSNAIPHLRALISPTLPITFMRNITWTWSNLCRKKTPYPC 118
Query: 248 WSIVSQALPTLSKLIYSMDTETLVDACWAISYLSDGPVNSIQAVVDARIPKRLVELLSHQ 307
+ V Q L LS L+ +E L +ACW++SYL+ G K L+ +
Sbjct: 119 ETAVKQMLRALS-LLQRHHSEVLSEACWSLSYLTYGC-------------KELIGQVDDT 164
Query: 308 STLVQTPAL-RAVGNIVTGNDLQTQIVINCGALAALRNLLASPKESIRKEACWTISNITA 366
+ P L R +GNI+TG + Q Q+ I+ G L L L K SI+ EA W +SN+ A
Sbjct: 165 GNSMSGPLLSRTMGNIITGTNEQKQMAIDAGMLNVLPQFLQHNKSSIQ-EAAWALSNVAA 223
Query: 367 GNTEQIQAVIDANLIPPLIRLLETAE-YKTKKEACWAISNASSGGLHKPEIIRYLVSQGC 425
G + Q ++ N++PP++ LL+ E K++K SG R+L Q
Sbjct: 224 GPSHHTQQLLAYNVLPPVVALLKKMENLKSRKRL--------SG--------RWLTLQYV 267
Query: 426 IKPLCDLLEIADNRIIEVTLDAIENILKMGEMDREVRGIAVNENADFIEKAGGMEKIFNL 485
+I+ + LD I IL+ E E + IE+ GG+++I L
Sbjct: 268 -------------KIVLIILDVISCILQAAEKRSEKEILCF-----LIEQLGGIDRIEAL 309
Query: 486 QSNANEKIYEKAFKIIEKYFS 506
Q + N +I + A IIEK+F+
Sbjct: 310 QLHENCQIGQSALNIIEKHFA 330
>Hs20538368 [U] KOG0166 Karyopherin (importin) alpha
Length = 317
Score = 128 bits (321), Expect = 2e-29
Identities = 83/232 (35%), Positives = 124/232 (52%), Gaps = 14/232 (6%)
Query: 272 DACWAISYLSDGPVNSIQAVVDARIPKRLVELLSHQSTLVQTPALRAVGNIVTGNDLQTQ 331
++ WA++ ++ G + +AVVD + LL+ + A+ AVGNI +
Sbjct: 70 ESAWALTNIASGALEQTKAVVDGGAIPAFIFLLASPHAHISEQAVWAVGNIAGDGSIFRD 129
Query: 332 IVINCGALAALRNLLASPKESIRKEACWTISNITAGNTEQIQAVIDANLIPPLIRLLETA 391
+VINCGA+ AL LLA P S AC + G+ +QI+ V++ L+P + +L A
Sbjct: 130 LVINCGAVDALLALLAVPDMS--SLAC----DYLPGHQDQIEQVVNHGLVPFFVNVLSKA 183
Query: 392 EYKTKKEACWAISNASSGGLHKPEIIRYLVSQGCIKPLCDLLEIADNRIIEVTLDAIENI 451
++KTKKE+ WA++N SS G E I Y V G IKPL +LL D + I V LDAI NI
Sbjct: 184 DFKTKKESVWAVTNYSSSG--TVEQIVYPVHCGIIKPLMNLLTARDTKFILVILDAISNI 241
Query: 452 LKMGEMDREVRGIAVNENADFIEKAGGMEKIFNLQSNANEKIYEKAFKIIEK 503
+ E + E ++ GG+EKI LQ++ NE + + +IEK
Sbjct: 242 FQAPEK------LGETEKPSMSKECGGLEKIEALQNHENESVCKALLSLIEK 287
Score = 117 bits (293), Expect = 4e-26
Identities = 76/219 (34%), Positives = 111/219 (49%), Gaps = 12/219 (5%)
Query: 143 LQLEAAWALTNIASGTSEQTRVVVDAGAVPLFIQLLYSNSVEVKEQAIWALGNVAGDSTD 202
+Q E+AWALTNIASG EQT+ VVD GA+P FI LL S + EQA+WA+GN+AGD +
Sbjct: 67 IQFESAWALTNIASGALEQTKAVVDGGAIPAFIFLLASPHAHISEQAVWAVGNIAGDGSI 126
Query: 203 YRDYVLQCGAMQPILYLFELNKTSLIRTATWTLSNLCRGKKPQPDWSIVSQALPTLSKLI 262
+RD V+ CGA+ +L L + S + + G + Q + + +P ++
Sbjct: 127 FRDLVINCGAVDALLALLAVPDMSSL------ACDYLPGHQDQIEQVVNHGLVPFFVNVL 180
Query: 263 YSMDTETLVDACWAI-SYLSDGPVNSIQAVVDARIPKRLVELLSHQSTLVQTPALRAVGN 321
D +T ++ WA+ +Y S G V I V I K L+ LL+ + T L A+ N
Sbjct: 181 SKADFKTKKESVWAVTNYSSSGTVEQIVYPVHCGIIKPLMNLLTARDTKFILVILDAISN 240
Query: 322 IV-----TGNDLQTQIVINCGALAALRNLLASPKESIRK 355
I G + + CG L + L ES+ K
Sbjct: 241 IFQAPEKLGETEKPSMSKECGGLEKIEALQNHENESVCK 279
Score = 51.6 bits (122), Expect = 3e-06
Identities = 42/142 (29%), Positives = 64/142 (44%), Gaps = 13/142 (9%)
Query: 353 IRKEACWTISNITAGNTEQIQAVIDANLIPPLIRLLETAEYKTKKEACWAISNASSGGLH 412
I+ E+ W ++NI +G EQ +AV+D IP I LL + ++A WA+ N + G
Sbjct: 67 IQFESAWALTNIASGALEQTKAVVDGGAIPAFIFLLASPHAHISEQAVWAVGNIAGDG-- 124
Query: 413 KPEIIRYLV-SQGCIKPLCDLLEIADNRIIEVTL-----DAIENILKMGEMDREVRGIAV 466
I R LV + G + L LL + D + D IE ++ G + V V
Sbjct: 125 --SIFRDLVINCGAVDALLALLAVPDMSSLACDYLPGHQDQIEQVVNHGLVPFFVN---V 179
Query: 467 NENADFIEKAGGMEKIFNLQSN 488
ADF K + + N S+
Sbjct: 180 LSKADFKTKKESVWAVTNYSSS 201
>At1g32880 [U] KOG0166 Karyopherin (importin) alpha
Length = 183
Score = 119 bits (297), Expect = 2e-26
Identities = 67/140 (47%), Positives = 95/140 (67%), Gaps = 4/140 (2%)
Query: 371 QIQAVIDANLIPPLIRLLETAEYKTKKEACWAISNASSGGLHKPEIIRYLVSQGCIKPLC 430
++Q+VIDANLIP L++L + AE+ KKE+ AISNA+ G H + I+Y+V Q CIKPLC
Sbjct: 40 KLQSVIDANLIPTLVKLTQNAEFDMKKESVCAISNATLLGSH--DQIKYMVEQSCIKPLC 97
Query: 431 DLLEIADNRIIEVTLDAIENILKMGEMDREVRGIAVNENADFIEKAGGMEKIFNLQSNAN 490
D+L D + I LD +EN LK+GE ++ G V+ IE A G++KI NLQ + N
Sbjct: 98 DILFCPDVKTILKCLDGMENTLKVGEAEKNA-GDDVSWYTRLIE-AEGLDKILNLQRHEN 155
Query: 491 EKIYEKAFKIIEKYFSDEDD 510
+IY+KA KI++ Y+ +EDD
Sbjct: 156 IEIYDKALKILQTYWLEEDD 175
>Hs17469107 [U] KOG0166 Karyopherin (importin) alpha
Length = 246
Score = 101 bits (252), Expect = 2e-21
Identities = 69/200 (34%), Positives = 104/200 (51%), Gaps = 34/200 (17%)
Query: 292 VDARIPKRLVELLSHQSTLVQTPALRAVGNIVTGNDLQTQIVINCGALAALRNLLASPKE 351
++ + +LV+LL + TPALRA+GNIVTG QTQ+VI+ ALA +LL PK
Sbjct: 1 METGVVPQLVKLLGASELPIVTPALRAIGNIVTGTGEQTQVVIDAEALAVFPSLLTDPKT 60
Query: 352 SIRKEACWTISNITAGNTEQIQAVIDANLIPPLIRLLETAEYKTKKEACWAISNASSGGL 411
+ KEA WT+SNITAG +QIQ V++ L+ L +L
Sbjct: 61 NTWKEAMWTMSNITAGRQDQIQQVVNHGLVLFLANVLS---------------------- 98
Query: 412 HKPEIIRYLVSQGCIKPLCDLLEIADNRIIEVTLDAIENILKMGEMDREVRGIAVNENAD 471
+I+R+ + +LL D ++I V LDAI +I + E E +++
Sbjct: 99 ---QILRHKRK----LTIDELLNCKDTKVILVILDAISSIFQAAEKLGETEKLSI----- 146
Query: 472 FIEKAGGMEKIFNLQSNANE 491
IE+ GG++KI LQ++ N+
Sbjct: 147 MIEECGGLDKIEALQNHEND 166
Score = 56.2 bits (134), Expect = 1e-07
Identities = 51/198 (25%), Positives = 90/198 (44%), Gaps = 17/198 (8%)
Query: 123 ISTGVVPTLVQFMSENQPEMLQLEAAWALTNIASGTSEQTRVVVDAGAVPLFIQLLYSNS 182
+ TGVVP LV+ + ++ ++ A A+ NI +GT EQT+VV+DA A+ +F LL
Sbjct: 1 METGVVPQLVKLLGASELPIVT-PALRAIGNIVTGTGEQTQVVIDAEALAVFPSLLTDPK 59
Query: 183 VEVKEQAIWALGNVAGDSTDYRDYVLQCGAMQPILYLFELNKTSLIRTATWTLSNLCRGK 242
++A+W + N+ D V+ G +L+L + L T+ L K
Sbjct: 60 TNTWKEAMWTMSNITAGRQDQIQQVVNHGL---VLFLANVLSQILRHKRKLTIDELLNCK 116
Query: 243 KPQPDWSIVSQALPTLSKLIYSM----DTETLVDACWAISYLSDGPVNSIQAVVDARIPK 298
D ++ L +S + + +TE L +I G ++ I+A+ +
Sbjct: 117 ----DTKVILVILDAISSIFQAAEKLGETEKL-----SIMIEECGGLDKIEALQNHENDL 167
Query: 299 RLVELLSHQSTLVQTPAL 316
R+ + + TL+ P L
Sbjct: 168 RVSDSCNQWYTLIIIPWL 185
>CE06461 [U] KOG0166 Karyopherin (importin) alpha
Length = 524
Score = 96.7 bits (239), Expect = 8e-20
Identities = 113/508 (22%), Positives = 212/508 (41%), Gaps = 38/508 (7%)
Query: 12 EYRRTNFKNKGRFSADELRRRRDVQQVELRKVKRDEALAKRRNFNAPVGNXXXXXXXXXX 71
E R +K+ R +E+RR+R +V++RK +RDE + R
Sbjct: 10 EERSKMYKSNVR-DQNEMRRKRREDEVQIRKNRRDEKFERNRQITVQRSLSHEETSELLK 68
Query: 72 XXXXXFYRQLQQELPAMLEQIHSN--DLQQQLAVTVKFRQVLSREHRPPIDLVISTGVVP 129
+ + L +H N + + V VK Q+L + + VIS
Sbjct: 69 SVADGLQSMQETTIHEALTVLHENLNNTVWTIHVLVKV-QILHKLSDVYCNRVIS----- 122
Query: 130 TLVQFMSENQPEMLQLEAAWALTNIASGTSE--QTRVVVDAGAVP--LFIQLLYSNSVEV 185
+ +L + L I SG E R D + +F Y +S ++
Sbjct: 123 -----------QTTRLLISRTLLKI-SGIDEVKYERYSSDDRCIQSLVFNISTYGSSEDI 170
Query: 186 KEQAIWALGNVAGDSTDYRDYVLQCGAMQPILYLFELNKTSLI-RTATWTLSNLCRG-KK 243
++ S YR+ L C + ++ +N + ++ R+ W + C +
Sbjct: 171 LCDTFQSIACFIIRSITYRNLALDCAIVSELIDASTINMSIILHRSLMWLVFLFCEKLDR 230
Query: 244 PQPDWSIVSQALPTLSKLIYSMDTETLVDACWAISYLSDGPVNSIQAVVDARIPKRLVEL 303
P ++ L +S I S D DA + + L++ P + D ++ +LV
Sbjct: 231 CSPHVDEIAPLLEIISNGIQSTDAMVQTDAASSCASLAEWPP-IYHYMSDLKLCSKLVAN 289
Query: 304 LSHQSTLVQTPALRAVGNIVTGNDLQTQIVINCGALAALRNLLASPKESIRKEACWTISN 363
L + + + +I+ T+ +I+ G L L+ + S +E C+ ISN
Sbjct: 290 LRNDKGNARPKVKAGINSIIQATGYFTEEMIDAGLLEVLKGFVNVSYMS--QEVCFIISN 347
Query: 364 ITAGNTEQIQAVIDANLIPPLIRLLETAEYKTKKEACWAISNASSGGLHKPEIIRYLVSQ 423
I + I +I + ++ + R++E +EY++++EA + I + + K + Y+V
Sbjct: 348 ICVEGEQTIDKLISSGVLREVARVMEASEYRSRREAAFVICHCCASANQKH--LEYVVEL 405
Query: 424 GCIKPLCDLLEIADNRIIEVTLDAIENILKMGEMDREVRGIAVNEN--ADFIEKAGGMEK 481
G + DLL D ++ LDAI +L+ GEM R + N N A +E+ G EK
Sbjct: 406 GMLSAFTDLLTCMDVSLVSYILDAIYLLLQFGEM----RLLPDNSNPVAIKLEEIGCREK 461
Query: 482 IFNLQSNANEKIYEKAFKIIEKYFSDED 509
+ L + + I+ +A+ II++++ D+D
Sbjct: 462 LEFLCESQSVDIHARAYTIIDRFYVDDD 489
>CE28029 [U] KOG0166 Karyopherin (importin) alpha
Length = 447
Score = 91.3 bits (225), Expect = 3e-18
Identities = 73/331 (22%), Positives = 148/331 (44%), Gaps = 32/331 (9%)
Query: 144 QLEAAWALTNIASGTSEQTRVVVDAGAVPLFIQLLYSNSVEVKEQAIWALGNVAGDSTDY 203
++ A W +TN+ + E T + V++ + + I+L+ S + + Q +WA+ N+A D +
Sbjct: 58 EVNAVWIITNMCCISQEVTHLFVNSNCLDILIKLVRSQNARLSSQTVWAIANIAADCSSC 117
Query: 204 RDYVLQCGAMQPILYLFELNKTSL------IRTATWTLSNLCRGKKPQPDWSIVSQALPT 257
+ L+C + + + L +TS R W ++N+ G + + +
Sbjct: 118 K---LKCRSPKLLKILARNLQTSYKLDDADRRQLIWCVNNIFSGGRTTMPSPVARSLICA 174
Query: 258 LSKLIYSMDTETLVD------ACWAISYLSDGPVNSIQAVVDARIPKRLV------ELLS 305
LS ++ +DT+ + + W ++ L D +++ + +D + + V + +
Sbjct: 175 LSAIL--LDTDAVDNMGCGSMILWTLANLVDNSLDTTR--IDMLLSQNYVVEHILEKFID 230
Query: 306 HQSTLVQTPALRAVGNIVTGNDLQTQIVINCGALAALRNLLASPKESIRKEACWTISNIT 365
LR +GNI GND+QT ++++ + N+ S E EA W ISN+
Sbjct: 231 QTDKSCNVSCLRLIGNIAVGNDVQTDLLVDNPKFRVVMNIAMSSPEH-HSEAAWIISNVV 289
Query: 366 AGNTEQIQAVID--ANLIPPLIRLLETAEYKTKKEACWAISN-ASSGGLHKPEIIRYLVS 422
AG + ++D ++ + T + + +KE W I N ++ H+ + LVS
Sbjct: 290 AGAPRHVDYIMDDPDAFYEWVMAGIHTGDKRLRKECLWIIGNLLATADEHQTYL---LVS 346
Query: 423 QGCIKPLCDLLEIADNRIIEVTLDAIENILK 453
G ++ LL+ D R+ E +L+
Sbjct: 347 LGIVQHFPALLDFDDVRLNEKAATTATELLR 377
>Hs6912678 [U] KOG0166 Karyopherin (importin) alpha
Length = 509
Score = 89.0 bits (219), Expect = 2e-17
Identities = 81/337 (24%), Positives = 151/337 (44%), Gaps = 7/337 (2%)
Query: 120 DLVISTGVVPTLVQFMSENQPEMLQLEAAWALTNIASGTSEQTRVVVDAGAVPLFIQLLY 179
+ V+ ++P LV ++E Q + AA+ L + + + + +VD GA+ + L
Sbjct: 77 EAVVKCDILPQLVYSLAE-QNRFYKKAAAFVLRAVGKHSPQLAQAIVDCGALDTLVICLE 135
Query: 180 SNSVEVKEQAIWALGNVAGDSTDYRDYVLQCGAMQPILYLFELNKTSLIRTATWTLSNLC 239
VKE A WAL +A + + V+ GA+ ++ + + +L R A LS++
Sbjct: 136 DFDPGVKEAAAWALRYIARHNAELSQAVVDAGAVPLLVLCIQEPEIALKRIAASALSDIA 195
Query: 240 RGKKPQPDWSIVSQALPTLSKLIYSMDTETLVDACWAISYLSDGPVNSIQAVVDARIPKR 299
+ + + A+ L+++I + D + A+S +S V+ + VV+A I
Sbjct: 196 KHSPELAQTVVDAGAVAHLAQMILNPDAKLKHQILSALSQVSKHSVDLAEMVVEAEIFPV 255
Query: 300 LVELLSHQSTLVQTPALRAVGNIVTGNDLQTQIVINCGALAALRNLLASPKESIRKEACW 359
++ L + V+ A + I +Q+V+N G +AA+ + + S K + R
Sbjct: 256 VLTCLKDKDEYVKKNASTLIREIAKHTPELSQLVVNAGGVAAVIDCIGSCKGNTRLPGIM 315
Query: 360 TISNITAGNTEQIQAVIDANLIPPL-IRLLETAEYKTKKEACWAISNASSGGLHKPEIIR 418
+ + A + AVI + +P L + L E E K A WA+ G H PE R
Sbjct: 316 MLGYVAAHSENLAMAVIISKGVPQLSVCLSEEPEDHIKAAAAWALGQI---GRHTPEHAR 372
Query: 419 YLVSQGCIKPLCDL-LEIADNRIIEV-TLDAIENILK 453
+ + L L + + ++V + AI+NIL+
Sbjct: 373 AVAVTNTLPVLLSLYMSTESSEDLQVKSKKAIKNILQ 409
Score = 67.4 bits (163), Expect = 5e-11
Identities = 51/184 (27%), Positives = 87/184 (46%), Gaps = 9/184 (4%)
Query: 273 ACWAISYLSDGPVNSIQAVVDARIPKRLVELLSHQSTLVQTPA---LRAVGNIVTGNDLQ 329
A A+ L++ + +AVV I +LV L+ Q+ + A LRAVG +
Sbjct: 61 AALALGRLANYNDDLAEAVVKCDILPQLVYSLAEQNRFYKKAAAFVLRAVGK---HSPQL 117
Query: 330 TQIVINCGALAALRNLLASPKESIRKEACWTISNITAGNTEQIQAVIDANLIPPLIRLLE 389
Q +++CGAL L L +++ A W + I N E QAV+DA +P L+ ++
Sbjct: 118 AQAIVDCGALDTLVICLEDFDPGVKEAAAWALRYIARHNAELSQAVVDAGAVPLLVLCIQ 177
Query: 390 TAEYKTKKEACWAISNASSGGLHKPEIIRYLVSQGCIKPLCDLLEIADNRIIEVTLDAIE 449
E K+ A A+S+ + H PE+ + +V G + L ++ D ++ L A+
Sbjct: 178 EPEIALKRIAASALSDIAK---HSPELAQTVVDAGAVAHLAQMILNPDAKLKHQILSALS 234
Query: 450 NILK 453
+ K
Sbjct: 235 QVSK 238
Score = 64.7 bits (156), Expect = 3e-10
Identities = 68/337 (20%), Positives = 129/337 (38%), Gaps = 47/337 (13%)
Query: 98 QQQLAVTVKFRQVLSREHRPP-IDLVISTGVVPTLVQFMSENQPEMLQLEAAWALTNIAS 156
Q Q A T + V RP I+ + + GV+ L + + P +Q AA AL +A+
Sbjct: 12 QYQKARTQFVQMVAELATRPQNIETLQNAGVMSLLRTLLLDVVPT-IQQTAALALGRLAN 70
Query: 157 GTSEQTRVVVDAGAVPLFIQLLYSNSVEVKEQAIWALGNVAGDSTDYRDYVLQCGAMQPI 216
+ VV +P + L + K+ A + L V S ++ CGA+ +
Sbjct: 71 YNDDLAEAVVKCDILPQLVYSLAEQNRFYKKAAAFVLRAVGKHSPQLAQAIVDCGALDTL 130
Query: 217 LYLFELNKTSLIRTATWTLSNLCRGKKPQPDWSIVSQALPTLSKLIYSMDTETLVDACWA 276
+ E + A W A
Sbjct: 131 VICLEDFDPGVKEAAAW------------------------------------------A 148
Query: 277 ISYLSDGPVNSIQAVVDARIPKRLVELLSHQSTLVQTPALRAVGNIVTGNDLQTQIVINC 336
+ Y++ QAVVDA LV + ++ A A+ +I + Q V++
Sbjct: 149 LRYIARHNAELSQAVVDAGAVPLLVLCIQEPEIALKRIAASALSDIAKHSPELAQTVVDA 208
Query: 337 GALAALRNLLASPKESIRKEACWTISNITAGNTEQIQAVIDANLIPPLIRLLETAEYKTK 396
GA+A L ++ +P ++ + +S ++ + + + V++A + P ++ L+ + K
Sbjct: 209 GAVAHLAQMILNPDAKLKHQILSALSQVSKHSVDLAEMVVEAEIFPVVLTCLKDKDEYVK 268
Query: 397 KEACWAISNASSGGLHKPEIIRYLVSQGCIKPLCDLL 433
K A I + H PE+ + +V+ G + + D +
Sbjct: 269 KNASTLIREIAK---HTPELSQLVVNAGGVAAVIDCI 302
Score = 52.0 bits (123), Expect = 2e-06
Identities = 40/177 (22%), Positives = 77/177 (42%), Gaps = 4/177 (2%)
Query: 277 ISYLSDGPVNSIQAVVDARIPKRLVELLSHQSTLVQTPALRAVGNIVTGNDLQTQIVINC 336
++ L+ P N I+ + +A + L LL +Q A A+G + ND + V+ C
Sbjct: 24 VAELATRPQN-IETLQNAGVMSLLRTLLLDVVPTIQQTAALALGRLANYNDDLAEAVVKC 82
Query: 337 GALAALRNLLASPKESIRKEACWTISNITAGNTEQIQAVIDANLIPPLIRLLETAEYKTK 396
L L LA +K A + + + + + QA++D + L+ LE + K
Sbjct: 83 DILPQLVYSLAEQNRFYKKAAAFVLRAVGKHSPQLAQAIVDCGALDTLVICLEDFDPGVK 142
Query: 397 KEACWAISNASSGGLHKPEIIRYLVSQGCIKPLCDLLEIADNRIIEVTLDAIENILK 453
+ A WA+ + H E+ + +V G + L ++ + + + A+ +I K
Sbjct: 143 EAAAWALRYIAR---HNAELSQAVVDAGAVPLLVLCIQEPEIALKRIAASALSDIAK 196
>Hs18562577 [U] KOG0166 Karyopherin (importin) alpha
Length = 548
Score = 87.8 bits (216), Expect = 4e-17
Identities = 67/222 (30%), Positives = 103/222 (46%), Gaps = 44/222 (19%)
Query: 38 VELRKVKRDEALAKRRNFNAPVGNXXXXXXXXXXXXXXXFYRQLQQELPAMLEQIHSNDL 97
V+LRK KRDE L KRRN + + +E +D+
Sbjct: 81 VKLRKNKRDEHLLKRRNVP---------------------HEDICEE----------SDI 109
Query: 98 QQQLAVTVKF-RQVLSREHRPPIDLVISTGVVPTLVQFMSENQPEMLQLEAAWALTNIAS 156
V ++ R++LS + PPID +I +G++ LV + + LQ EAAWALTNIA
Sbjct: 110 DGDYRVQIQAARKLLSSDRNPPIDDLIKSGILAILVHCLERDDNPCLQFEAAWALTNIAF 169
Query: 157 GTSEQTRVVVDAGAVPLFIQLLYSNSVEVKEQAIWALGNVAGDSTDYRDYVLQCGAMQPI 216
GTSEQT+ V + + V+V+ A+ A+GN+ + + VL C A+
Sbjct: 170 GTSEQTQAVA------------HHHEVKVQTAALRAVGNIIMGTDEQTQVVLNCDALLHF 217
Query: 217 LYLFELNKTSLIRTATWTLSNLCRGKKPQPDWSIVSQALPTL 258
L K + + A W LSN+ G + Q + SQ + ++
Sbjct: 218 PALLTHPKEKINKEAVWFLSNITAGSQQQSLGRLDSQRVASI 259
Score = 86.3 bits (212), Expect = 1e-16
Identities = 56/145 (38%), Positives = 72/145 (49%), Gaps = 13/145 (8%)
Query: 238 LCRGKKPQPDWSIVSQALPTLSKLIYSMDTETL-VDACWAISYLSDGPVNSIQAVVDARI 296
L + P D I S L L + D L +A WA++ ++ G QAV
Sbjct: 124 LSSDRNPPIDDLIKSGILAILVHCLERDDNPCLQFEAAWALTNIAFGTSEQTQAVAH--- 180
Query: 297 PKRLVELLSHQSTLVQTPALRAVGNIVTGNDLQTQIVINCGALAALRNLLASPKESIRKE 356
H VQT ALRAVGNI+ G D QTQ+V+NC AL LL PKE I KE
Sbjct: 181 ---------HHEVKVQTAALRAVGNIIMGTDEQTQVVLNCDALLHFPALLTHPKEKINKE 231
Query: 357 ACWTISNITAGNTEQIQAVIDANLI 381
A W +SNITAG+ +Q +D+ +
Sbjct: 232 AVWFLSNITAGSQQQSLGRLDSQRV 256
Score = 52.4 bits (124), Expect = 2e-06
Identities = 27/66 (40%), Positives = 44/66 (65%), Gaps = 4/66 (6%)
Query: 468 ENADFIEKAGGMEKIFNLQSNANEKIYEKAFKIIEKYFSDEDDVVDESMAPQT-AGNTFG 526
E+ + IE+ GG+EKI LQ++ NE IY+ A++II+++ ++ D S+ P+ G TFG
Sbjct: 480 EDGNLIEEDGGLEKIKQLQNHENEDIYKLAYEIIDQFMIIDE---DPSLVPEAIQGGTFG 536
Query: 527 FGSNVN 532
F S+ N
Sbjct: 537 FNSSAN 542
>YEL013w [U] KOG4224 Armadillo repeat protein VAC8 required for vacuole
fusion inheritance and cytosol-to-vacuole protein
targeting
Length = 578
Score = 83.2 bits (204), Expect = 9e-16
Identities = 100/431 (23%), Positives = 189/431 (43%), Gaps = 36/431 (8%)
Query: 85 LPAMLEQIHSNDLQQQLAVTVKFRQVLSREHRPPIDLVISTGVVPTLVQFMSENQPEMLQ 144
L A+ ++S++L Q + + F ++ + R +S V+ ++ + P+ +Q
Sbjct: 49 LKALTTLVYSDNLNLQRSAALAFAEITEKYVRQ-----VSREVLEPILILLQSQDPQ-IQ 102
Query: 145 LEAAWALTNIASGTSEQTRVVVDAGAVPLFIQLLYSNSVEVKEQAIWALGNVAGDSTDYR 204
+ A AL N+A + +V G PL Q++ N VEV+ A+ + N+A D +
Sbjct: 103 VAACAALGNLAVNNENKLLIVEMGGLEPLINQMMGDN-VEVQCNAVGCITNLA-TRDDNK 160
Query: 205 DYVLQCGAMQPILYLFELNKTSLIRTATWTLSNLCRGKKPQPDWSIVSQALPTLSKLIYS 264
+ GA+ P+ L + + R AT L N+ ++ + + + + A+P L L+ S
Sbjct: 161 HKIATSGALIPLTKLAKSKHIRVQRNATGALLNMTHSEENRKE-LVNAGAVPVLVSLLSS 219
Query: 265 MDTETLVDACWAISYLSDGPVNSIQ-AVVDARIPKRLVELLSHQSTLVQTPALRAVGNIV 323
D + A+S ++ N + A + R+ +LV L+ S+ V+ A A+ N+
Sbjct: 220 TDPDVQYYCTTALSNIAVDEANRKKLAQTEPRLVSKLVSLMDSPSSRVKCQATLALRNLA 279
Query: 324 TGNDLQTQIVINCGALAALRNLLASPKESIRKEACWTISNITAGNTEQIQAVIDANLIPP 383
+ Q +IV G L L L+ S + + I NI+ + ++DA + P
Sbjct: 280 SDTSYQLEIV-RAGGLPHLVKLIQSDSIPLVLASVACIRNISIHPLNE-GLIVDAGFLKP 337
Query: 384 LIRLLETAEYKTKKE-ACWAISN----ASSGGLHKPEIIRYLVSQGCIKPLCD------- 431
L+RLL +YK +E C A+S A+S ++ E + C + D
Sbjct: 338 LVRLL---DYKDSEEIQCHAVSTLRNLAASSEKNRKEFFESGAVEKCKELALDSPVSVQS 394
Query: 432 -------LLEIAD-NRIIEVTLDAIENILKMG-EMDREVRGIAVNENADFIEKAGGMEKI 482
+L +AD +++ + + ++ ++ M ++EV G A A+ + KI
Sbjct: 395 EISACFAILALADVSKLDLLEANILDALIPMTFSQNQEVSGNAAAALANLCSRVNNYTKI 454
Query: 483 FNLQSNANEKI 493
NE I
Sbjct: 455 IEAWDRPNEGI 465
>SPBC354.14c [U] KOG4224 Armadillo repeat protein VAC8 required for vacuole
fusion inheritance and cytosol-to-vacuole protein
targeting
Length = 550
Score = 71.6 bits (174), Expect = 3e-12
Identities = 84/355 (23%), Positives = 160/355 (44%), Gaps = 15/355 (4%)
Query: 82 QQELPAMLEQIHSNDLQQQLAVTVKFRQVLSREHRPPIDLVISTGVVPTLVQFMSENQPE 141
++ L A+ +S++L Q + + F ++ ++ R V + P L F+ ++
Sbjct: 46 EEPLRALTILAYSDNLDLQRSAALAFAEITEKDVRE----VDRETIEPVL--FLLQSPDA 99
Query: 142 MLQLEAAWALTNIASGTSEQTRVVVDAGAVPLFIQLLYSNSVEVKEQAIWALGNVAGDST 201
+Q A+ AL N+A +E +VV + L I+ + S VEV+ A+ + N+A
Sbjct: 100 EIQRAASVALGNLAVN-AENKALVVKLNGLDLLIRQMMSPHVEVQCNAVGCITNLA-TLD 157
Query: 202 DYRDYVLQCGAMQPILYLFELNKTSLIRTATWTLSNLCRGKKPQPDWSIVSQALPTLSKL 261
+ + + GA+ P+ L + + R AT L N+ + + + + +P L L
Sbjct: 158 ENKSKIAHSGALGPLTRLAKSKDIRVQRNATGALLNMTHSYENRQQ-LVSAGTIPVLVSL 216
Query: 262 IYSMDTETLVDACWAISYLSDGPVNSIQ-AVVDARIPKRLVELLSHQSTLVQTPALRAVG 320
+ S DT+ +IS ++ V+ + A + ++ + L++L+ S VQ A A+
Sbjct: 217 LPSSDTDVQYYCTTSISNIAVDAVHRKRLAQSEPKLVRSLIQLMDTSSPKVQCQAALALR 276
Query: 321 NIVTGNDLQTQIVINCGALAALRNLLASPKESIRKEACWTISNITAGNTEQIQAVIDANL 380
N+ + Q +IV AL +L LL S + + I NI+ + +IDA
Sbjct: 277 NLASDERYQIEIV-QSNALPSLLRLLRSSYLPLILASVACIRNISIHPLNE-SPIIDAGF 334
Query: 381 IPPLIRLLETAEYKTKKEACWAISNASSGGLHKPEIIRYLVSQGCIKPL-CDLLE 434
+ PL+ LL E ++ C A+S + R ++ I+ L C +L+
Sbjct: 335 LRPLVDLLSCTE--NEEIQCHAVSTLRNLAASSERNKRAIIEANAIQKLRCLILD 387
Score = 67.8 bits (164), Expect = 4e-11
Identities = 69/310 (22%), Positives = 144/310 (46%), Gaps = 29/310 (9%)
Query: 135 MSENQPEMLQLEAAWALTNIASGTSEQTRVVVDAGAVPLFIQLLYSNSVEVKEQAIWALG 194
+++++ +Q A AL N+ + E + +V AG +P+ + LL S+ +V+ ++
Sbjct: 175 LAKSKDIRVQRNATGALLNMTH-SYENRQQLVSAGTIPVLVSLLPSSDTDVQYYCTTSIS 233
Query: 195 NVAGDSTDYRDYVLQC--GAMQPILYLFELNKTSLIRTATWTLSNLCRGKKPQPDWSIVS 252
N+A D+ +R + Q ++ ++ L + + + A L NL ++ Q + + S
Sbjct: 234 NIAVDAV-HRKRLAQSEPKLVRSLIQLMDTSSPKVQCQAALALRNLASDERYQIE-IVQS 291
Query: 253 QALPTLSKLIYSMDTETLVDACWAISYLSDGPVNSIQAVVDARIPKRLVELLS-HQSTLV 311
ALP+L +L+ S ++ + I +S P+N ++DA + LV+LLS ++ +
Sbjct: 292 NALPSLLRLLRSSYLPLILASVACIRNISIHPLNE-SPIIDAGFLRPLVDLLSCTENEEI 350
Query: 312 QTPALRAVGNIVTGNDLQTQIVINCGALAALRNLLASPKESIRKE--AC----------- 358
Q A+ + N+ ++ + +I A+ LR L+ S++ E AC
Sbjct: 351 QCHAVSTLRNLAASSERNKRAIIEANAIQKLRCLILDAPVSVQSEMTACLAVLALSDEFK 410
Query: 359 -----WTISNITAGNTEQIQAVIDANLIPPLIRLLETAEYKTKKEACWAISNASSGGLHK 413
+ I N+ T+ + + N L L + ++ CW ++ +GG+H
Sbjct: 411 SYLLNFGICNVLIPLTDSMSIEVQGNSAAALGNLSSNVDDYSRFIECW---DSPAGGIH- 466
Query: 414 PEIIRYLVSQ 423
++R+L S+
Sbjct: 467 GYLVRFLSSE 476
>At5g19330 [S] KOG0167 FOG: Armadillo/beta-catenin-like repeats
Length = 636
Score = 70.9 bits (172), Expect = 5e-12
Identities = 76/358 (21%), Positives = 154/358 (42%), Gaps = 41/358 (11%)
Query: 147 AAWALTNIASGTSEQTRVVVDAGAVPLFIQLLYSNSV------------EVKEQAIWALG 194
A L +A + V+VD GAVP + L + EV++ + +ALG
Sbjct: 74 ATQVLAELAKNAEDLVNVIVDGGAVPALMTHLQAPPYNDGDLAEKPYEHEVEKGSAFALG 133
Query: 195 NVAGDSTDYRDYVLQCGAMQPILYLFELNK--------TSLIRTATWTLSNLCRGKKPQP 246
+A +Y+ ++ GA+ ++ L + NK S+IR A ++NL
Sbjct: 134 LLA-IKPEYQKLIVDKGALPHLVNLLKRNKDGSSSRAVNSVIRRAADAITNLAHENSSIK 192
Query: 247 DWSIVSQALPTLSKLIYSMDTETLVDACWAISYLSDGPVNSIQAVVDARIPKRLVELLSH 306
V +P L +L+ D++ A A+ L+ ++ +V+ L+ +L
Sbjct: 193 TRVRVEGGIPPLVELLEFSDSKVQRAAAGALRTLAFKNDDNKNQIVECNALPTLILMLGS 252
Query: 307 QSTLVQTPALRAVGNIVTGNDLQTQIVINCGALAALRNLLASPKESIRKEACWTISNITA 366
+ + A+ +GN+V + + V+ GAL + LL+S ++EA + +
Sbjct: 253 EDAAIHYEAVGVIGNLVHSSPHIKKEVLTAGALQPVIGLLSSCCPESQREAALLLGQFAS 312
Query: 367 GNTEQIQAVIDANLIPPLIRLLETAEYKTKKEACWAISNASSGGLHKPEIIRYLVSQGCI 426
+++ ++ + PLI +L++ + + K+ + +A+ + ++ I G +
Sbjct: 313 TDSDCKVHIVQRGAVRPLIEMLQSPDVQLKEMSAFALGRLAQDAHNQAGI----AHSGGL 368
Query: 427 KPLCDLLEIADNRIIEVTLDAIENILKMGEMDREVRGIAVNEN--ADFIEKAGGMEKI 482
PL LL+ + + A+ G+A NE+ +DFI + GG++K+
Sbjct: 369 GPLLKLLDSRNGSLQHNAAFAL-------------YGLADNEDNVSDFI-RVGGIQKL 412
>At5g13060 [S] KOG0167 FOG: Armadillo/beta-catenin-like repeats
Length = 706
Score = 70.1 bits (170), Expect = 8e-12
Identities = 90/391 (23%), Positives = 167/391 (42%), Gaps = 51/391 (13%)
Query: 118 PIDLVISTG--VVPTLVQFMSENQPEMLQLEAAWALTNIASGTSEQTRVVVDAGAVPLFI 175
PIDLV++ V F + EAA + ++A E ++V+ GA+P +
Sbjct: 42 PIDLVVAIRRHVEVLNSSFSDPDFDHEAVKEAAADIADLAK-IDENVEIIVENGAIPALV 100
Query: 176 QLLYSNSV-----------EVKEQAIWALGNVAGDSTDYRDYVLQCGAMQPILYLFE--- 221
+ L S V ++++ ALG +A Y+ ++ GA+ P + L +
Sbjct: 101 RYLESPLVVCGNVPKSCEHKLEKDCALALGLIAAIQPGYQQLIVDAGAIVPTVKLLKRRG 160
Query: 222 -----LNKTSLIRTATWTLSNLCRGKKPQPDWSIVSQALPTLSKLIYSMDTETLVDACWA 276
+ ++IR A ++N+ V + L +L+ D + A A
Sbjct: 161 ECGECMFANAVIRRAADIITNIAHDNPRIKTNIRVEGGIAPLVELLNFPDVKVQRAAAGA 220
Query: 277 ---ISYLSDGPVNSIQAVVDARIPKRLVELLSHQSTLVQTPALRAVGNIVTGNDLQTQIV 333
+S+ +D + + A+ LV +L Q + V A+ A+GN+V + + V
Sbjct: 221 LRTVSFRNDENKSQLNAL------PTLVLMLQSQDSTVHGEAIGAIGNLVHSSPDIKKEV 274
Query: 334 INCGALAALRNLLASPKESIRKEACWTISNITAGNTEQIQAVIDANLIPPLIRLLETAEY 393
I GAL + LL+S ++EA I A +++ + I PLI++LE+++
Sbjct: 275 IRAGALQPVIGLLSSTCLETQREAALLIGQFAAPDSDCKVHIAQRGAITPLIKMLESSDE 334
Query: 394 KTKKEACWAISNASSGGLHKPEIIRYLVSQGCIKPLCDLLEIADNRIIEVTLDAIENILK 453
+ + + +A+ + ++ I +G I L +LL++ + A+
Sbjct: 335 QVVEMSAFALGRLAQDAHNQAGI----AHRGGIISLLNLLDVKTGSVQHNAAFAL----- 385
Query: 454 MGEMDREVRGIAVNEN--ADFIEKAGGMEKI 482
G+A NE ADFI KAGG++K+
Sbjct: 386 --------YGLADNEENVADFI-KAGGIQKL 407
Score = 53.9 bits (128), Expect = 6e-07
Identities = 38/153 (24%), Positives = 73/153 (46%), Gaps = 5/153 (3%)
Query: 88 MLEQIHSNDLQQQLAVTVKFRQVLSREHRPPIDLVISTGVVPTLVQFMSENQPEMLQLEA 147
++E ++ D++ Q A R V R L +PTLV M ++Q + EA
Sbjct: 202 LVELLNFPDVKVQRAAAGALRTVSFRNDENKSQL----NALPTLV-LMLQSQDSTVHGEA 256
Query: 148 AWALTNIASGTSEQTRVVVDAGAVPLFIQLLYSNSVEVKEQAIWALGNVAGDSTDYRDYV 207
A+ N+ + + + V+ AGA+ I LL S +E + +A +G A +D + ++
Sbjct: 257 IGAIGNLVHSSPDIKKEVIRAGALQPVIGLLSSTCLETQREAALLIGQFAAPDSDCKVHI 316
Query: 208 LQCGAMQPILYLFELNKTSLIRTATWTLSNLCR 240
Q GA+ P++ + E + ++ + + L L +
Sbjct: 317 AQRGAITPLIKMLESSDEQVVEMSAFALGRLAQ 349
>Hs10863903_1 [O] KOG0168 Putative ubiquitin fusion degradation protein
Length = 1342
Score = 63.9 bits (154), Expect = 6e-10
Identities = 62/257 (24%), Positives = 111/257 (43%), Gaps = 16/257 (6%)
Query: 88 MLEQIHSNDLQQQLAVTVKFRQVLSREHRPPIDLVISTGVVPTLVQFMSENQPEMLQLEA 147
+L+ + ++D QQL ++ Q+L + + VVP L+ + + A
Sbjct: 442 LLQGLQASDESQQLQAVIEMCQLLVMGNEETLGGFPVKSVVPALITLLQMEHNFDIMNHA 501
Query: 148 AWALTNIASGTSEQTRVVVDAGAVPLFIQ-LLYSNSVEVKEQAIWALGNVAGDSTDYRDY 206
ALT + + VVVD A+P+F++ L ++V EQA+ AL + S +
Sbjct: 502 CRALTYMMEALPRSSAVVVD--AIPVFLEKLQVIQCIDVAEQALTALEML---SRRHSKA 556
Query: 207 VLQCGAMQPILYLFELNKTSLIRTATWTLSNLCRGKKPQPDWSIVSQALPTLSKLIYSMD 266
+LQ G + L E + R A +N C+ P ++ V+ +LP L++ + D
Sbjct: 557 ILQAGGLADCLLYLEFFSINAQRNALAIAANCCQSITPD-EFHFVADSLPLLTQRLTHQD 615
Query: 267 TETLVDACWAISYLSDG---PVNSIQAVVDARIPKRLVELLSHQSTLVQTPALRAVGNIV 323
+++ C + L D N +Q V + L + Q LV TP + + G +
Sbjct: 616 KKSVESTCLCFARLVDNFQHEENLLQQVASKDL------LTNVQQLLVVTPPILSSGMFI 669
Query: 324 TGNDLQTQIVINCGALA 340
+ + + NC LA
Sbjct: 670 MVVRMFSLMCSNCPTLA 686
>At4g38610 [O] KOG0168 Putative ubiquitin fusion degradation protein
Length = 1083
Score = 57.0 bits (136), Expect = 7e-08
Identities = 51/195 (26%), Positives = 91/195 (46%), Gaps = 15/195 (7%)
Query: 128 VPTLVQFMSENQPEMLQLEAAWALTNIASGTSEQTRVVVDAGAVPLFI-QLLYSNSVEVK 186
VP LV ++ + L AA ALT++ VV GAV + +LL +++
Sbjct: 239 VPVLVGLLNHESNPDIMLLAARALTHLCDVLPSSCAAVVHYGAVSCLVARLLTIEYMDLA 298
Query: 187 EQAIWALGNVAGDSTDYRDYVLQCGAMQPILYLFELNKTSLIRTATWTLSNLCRGKKPQP 246
EQ++ AL + S ++ L+ GA+ +L + T + R A T +N+C+ K P
Sbjct: 299 EQSLQALKKI---SQEHPTACLRAGALMAVLSYLDFFSTGVQRVALSTAANMCK-KLPSD 354
Query: 247 DWSIVSQALPTLSKLIYSMDTETLVDACWAISYLSDGPVNSIQAVVDARIPKRLVELLSH 306
V +A+P L+ L+ D++ L A ++ +++ A P++L EL +H
Sbjct: 355 ASDYVMEAVPLLTNLLQYHDSKVLEYASICLTRIAE---------AFAPYPEKLDELCNH 405
Query: 307 QSTLVQTPALRAVGN 321
+ Q +L + N
Sbjct: 406 -GLVTQAASLISTSN 419
>At1g77460 [S] KOG0167 FOG: Armadillo/beta-catenin-like repeats
Length = 2110
Score = 55.5 bits (132), Expect = 2e-07
Identities = 101/467 (21%), Positives = 186/467 (39%), Gaps = 75/467 (16%)
Query: 95 NDLQQQLAVTVKFRQVLSREHRPPIDLVISTGVVPTLVQFMSENQPEMLQLEAAWALTNI 154
N Q A ++ R VLS I ++++GVV +L+Q + + ++ AA AL +
Sbjct: 201 NPNSQANAASLLARLVLS--FCDSIQKILNSGVVKSLIQLLEQKNDINVRASAADALEAL 258
Query: 155 ASGTSEQTRVVVDAGAVPLFIQLLYSNSVE---------VKEQAIWALGNVAGDSTDYRD 205
++ + E + V DAG V I+ + + S E ++E A AL NV G
Sbjct: 259 SANSDEAKKCVKDAGGVHALIEAIVAPSKECMQGKHGQSLQEHATGALANVFG------- 311
Query: 206 YVLQCGAMQPILYLFELNK----TSLIRTATWTLS-NLCRGKKPQPDWSIVSQAL--PTL 258
G I+YL ++++ T I L+ L K+P+ +I ++ L
Sbjct: 312 -----GMRHLIIYLGQVSQSPRLTEPIGDVIGALAYALMIFKQPESSENIFDPSVIESIL 366
Query: 259 SKLIYSMDTETLVDACWAISYLSDGPVNSIQAVVDARIPKRLVELLSHQSTLVQTPALRA 318
KL+ DT+ + + G + + DA + L+ L++ S V+ +
Sbjct: 367 VKLLKPRDTKLIQERILEAMASLYGNSSLSCYLDDAEAKRVLIALITMASADVRERLIIC 426
Query: 319 VGNIVTGNDLQTQIVINCGALAALRNLLASPKESIRKEACWTISNITAGNTEQIQAVIDA 378
+ + + + + + L E ++ A + +TA + AV A
Sbjct: 427 LSGLCHDKVGIWEAIGKREGIQLFISFLGLSSEQHQEYAVEMLKILTAQVDDSKWAVTAA 486
Query: 379 NLIPPLIRLLETAEYKTKKEACWAISN------------ASSGGLHKPEIIRYLVSQG-- 424
IPPL++LLET K K++A + N +GG+ P + L + G
Sbjct: 487 GGIPPLVQLLETGSQKAKEDAACILWNLCCHSEEIRDCVERAGGI--PAFLWLLKTGGPN 544
Query: 425 ----CIKPLCDLLEIAD----NRIIEVTL-----------DAIENIL-KMGEMDREVRGI 464
K L L+ AD N+++ + L + + ++L K + D RG
Sbjct: 545 SQETSAKTLVKLVHTADPATINQLLALLLGDDPTSKIQVIEVLGHVLSKASQEDLVHRGC 604
Query: 465 AVNENADFIEKAGGMEKIFNLQSNANEKIYEKAFKIIEKYFSDEDDV 511
A N+ G+ + +++ E+ E ++ FS D+
Sbjct: 605 AANK---------GLRSLVESLTSSREETKEHTASVLADLFSSRQDI 642
>At1g23180 [S] KOG0167 FOG: Armadillo/beta-catenin-like repeats
Length = 452
Score = 54.7 bits (130), Expect = 3e-07
Identities = 91/406 (22%), Positives = 168/406 (40%), Gaps = 66/406 (16%)
Query: 123 ISTGVVPTLVQFMSENQPEMLQLEAAWALTNIASGTSEQTRVVVDAGAVPLFIQLLYSN- 181
+ G V LVQ ++ N E ++L AL N++ + R+ + GAV I LL
Sbjct: 81 MEAGAVKPLVQLLANNNKETVKLPVIRALKNLSLSRTVCQRIEAE-GAVWFLINLLKQPE 139
Query: 182 -SVEVKEQAIWAL----------------GNVAGDSTDYRDYVLQCGAMQPILYLFELNK 224
S+ V E + + G V G D R VL ++ + +
Sbjct: 140 ISLNVTEHVLDIIAHILDPSKEMESKFYEGPVNGSKADSRKEVLDAAVFSRLVQIAKTAS 199
Query: 225 TSLIRTATWTLSNLCRGKKPQPDWSIVSQALPTLSKLIYSMDTETLVDACWAISYLSDGP 284
+L+R A + ++ I+S P + +I S D T++D L + P
Sbjct: 200 PNLLRNAISVI-----------EFGIISN--PNMDTII-SKDITTVLDLALRQKVLEE-P 244
Query: 285 VNSIQAVVDARIPKRLVELLSHQSTLVQTPALRAVGNIVTGNDLQTQIVINCGALAALRN 344
N + + K L++L ++ L + A R + ++ + Q + + +R
Sbjct: 245 ENEAE-----ELEKHLLKL--EEAGLTISAASRLLTKLLDSESFR-QTIDTAVFIELVRK 296
Query: 345 LLASPKESIRKE---ACWTISNITAGNTEQIQAVIDANL-----IPPLIRLLE-TAEYKT 395
+L S K+ AC + ++ + I+ + IP L+ + ++ +T
Sbjct: 297 ILRSSLPLHYKDWVAACLVKLTALSSPSQSLNNPINLEVTLYKTIPSLVEQMSFSSSPET 356
Query: 396 KKEACWAISNASSGGLHKPEIIRYLVSQGCIKPLCDLLEIADNRIIEVTLDAIENILKMG 455
K+ A ++ S G+ PE I+ L SQG I+PL LLE + R +E +L + N+
Sbjct: 357 KEAAVLELNKIVSEGV--PESIQTLASQGGIEPLVKLLEERNERCVEASLSVLYNL---- 410
Query: 456 EMDREVRGIAVNENADFIEKAGGMEKIFNLQSNANEKIYEKAFKII 501
MD +EN I +AG + + + + + +EKA +++
Sbjct: 411 TMD--------SENHTAIIRAGAVPVLRRIVMSQRPQ-WEKALRLL 447
>At1g23030 [S] KOG0167 FOG: Armadillo/beta-catenin-like repeats
Length = 612
Score = 54.7 bits (130), Expect = 3e-07
Identities = 64/289 (22%), Positives = 122/289 (42%), Gaps = 10/289 (3%)
Query: 167 DAGAVPLFIQLLYSNSVEVKEQAIWALGNVAGDSTDYRDYVLQCGAMQPILYLFELNKTS 226
D + +Q L S S E + A+ + +++ STD R + + GA+ ++ L +
Sbjct: 329 DMSVIRALVQRLSSRSTEDRRNAVSEIRSLSKRSTDNRILIAEAGAIPVLVNLLTSEDVA 388
Query: 227 LIRTATWTLSNLCRGKKPQPDWSIVSQALPTLSKLIYSMDTETLVDACWAISYLSDGPVN 286
A + NL + + + + A+ ++ +++ + E +A + LS N
Sbjct: 389 TQENAITCVLNLSIYEN-NKELIMFAGAVTSIVQVLRAGTMEARENAAATLFSLSLADEN 447
Query: 287 SIQAVVDARIPKRLVELLSHQSTLVQTPALRAVGN--IVTGNDLQTQIVINCGALAALRN 344
I IP LV+LL + + + A A+ N I GN + + G + AL
Sbjct: 448 KIIIGGSGAIP-ALVDLLENGTPRGKKDAATALFNLCIYHGNKGR---AVRAGIVTALVK 503
Query: 345 LLASPKESIRKEACWTISNITAGNTEQIQAVIDANLIPPLIRLLETAEYKTKKEACWAIS 404
+L+ + TI ++ A N + A++ AN +P LI +L+T + + ++ A +
Sbjct: 504 MLSDSTRHRMVDEALTILSVLANNQDAKSAIVKANTLPALIGILQTDQTRNRENAAAILL 563
Query: 405 NASSGGLHKPEIIRYLVSQGCIKPLCDLLEIADNRIIEVTLDAIENILK 453
+ K I L G + PL DL + R + +E + K
Sbjct: 564 SLCKRDTEKLITIGRL---GAVVPLMDLSKNGTERGKRKAISLLELLRK 609
Score = 53.5 bits (127), Expect = 8e-07
Identities = 59/276 (21%), Positives = 122/276 (43%), Gaps = 10/276 (3%)
Query: 127 VVPTLVQFMSENQPEMLQLEAAWALTNIASGTSEQTRVVVDAGAVPLFIQLLYSNSVEVK 186
V+ LVQ +S E + A + +++ +++ ++ +AGA+P+ + LL S V +
Sbjct: 332 VIRALVQRLSSRSTEDRR-NAVSEIRSLSKRSTDNRILIAEAGAIPVLVNLLTSEDVATQ 390
Query: 187 EQAIWALGNVAGDSTDYRDYVLQCGAMQPILYLFELNKTSLIRTATWTLSNLCRGKKPQP 246
E AI + N++ + ++ ++ GA+ I+ + A TL +L + +
Sbjct: 391 ENAITCVLNLSIYENN-KELIMFAGAVTSIVQVLRAGTMEARENAAATLFSLSLADENK- 448
Query: 247 DWSIV---SQALPTLSKLIYSMDTETLVDACWAISYLSDGPVNSIQAVVDARIPKRLVEL 303
I+ S A+P L L+ + DA A+ L N +A V A I LV++
Sbjct: 449 ---IIIGGSGAIPALVDLLENGTPRGKKDAATALFNLCIYHGNKGRA-VRAGIVTALVKM 504
Query: 304 LSHQSTLVQTPALRAVGNIVTGNDLQTQIVINCGALAALRNLLASPKESIRKEACWTISN 363
LS + + +++ N ++ L AL +L + + R+ A + +
Sbjct: 505 LSDSTRHRMVDEALTILSVLANNQDAKSAIVKANTLPALIGILQTDQTRNRENAAAILLS 564
Query: 364 ITAGNTEQIQAVIDANLIPPLIRLLETAEYKTKKEA 399
+ +TE++ + + PL+ L + + K++A
Sbjct: 565 LCKRDTEKLITIGRLGAVVPLMDLSKNGTERGKRKA 600
>At4g12710 [S] KOG0167 FOG: Armadillo/beta-catenin-like repeats
Length = 402
Score = 53.9 bits (128), Expect = 6e-07
Identities = 35/137 (25%), Positives = 72/137 (52%), Gaps = 4/137 (2%)
Query: 85 LPAMLEQIHSNDLQQQLAVTVKFRQVLSREHRPPIDLVISTGVVPTLVQFMSENQPEMLQ 144
+P ++ + S+++ + A + + R R I++V G VP L+Q + + + +
Sbjct: 92 IPPLVPMLFSSNVDARHASLLALLNLAVRNERNKIEIV-KAGAVPPLIQILKLHNASLRE 150
Query: 145 LEAAWALTNIASGTSEQTRVVVDAGAVPLFIQLLYSNSVEVKEQAIWALGNVAGDSTDYR 204
L A LT A+ ++ +++ +G PL IQ+L S +V+ K A+ AL N++ +Y
Sbjct: 151 LATAAILTLSAAPANKA--MIISSGVPPLLIQMLSSGTVQGKVDAVTALHNLSA-CKEYS 207
Query: 205 DYVLQCGAMQPILYLFE 221
+L A+ P+++L +
Sbjct: 208 APILDAKAVYPLIHLLK 224
Score = 50.1 bits (118), Expect = 9e-06
Identities = 38/141 (26%), Positives = 73/141 (50%), Gaps = 4/141 (2%)
Query: 165 VVDAGAVPLFIQLLYSNSVEVKEQAIWALGNVAGDSTDYRDYVLQCGAMQPILYLFELNK 224
+ DAG +P + +L+S++V+ + ++ AL N+A + + +++ GA+ P++ + +L+
Sbjct: 86 LADAGVIPPLVPMLFSSNVDARHASLLALLNLAVRNERNKIEIVKAGAVPPLIQILKLHN 145
Query: 225 TSLIRTATWTLSNLCRGKKPQPDWSIVSQAL-PTLSKLIYSMDTETLVDACWAISYLSDG 283
SL AT + L P I+S + P L +++ S + VDA A+ LS
Sbjct: 146 ASLRELATAAILTL--SAAPANKAMIISSGVPPLLIQMLSSGTVQGKVDAVTALHNLSAC 203
Query: 284 PVNSIQAVVDARIPKRLVELL 304
S ++DA+ L+ LL
Sbjct: 204 KEYS-APILDAKAVYPLIHLL 223
>At1g01830 [S] KOG0167 FOG: Armadillo/beta-catenin-like repeats
Length = 571
Score = 51.6 bits (122), Expect = 3e-06
Identities = 65/319 (20%), Positives = 135/319 (41%), Gaps = 18/319 (5%)
Query: 150 ALTNIASGTSEQTRVV----VDAGAVPLFIQLLYSNSVEVKEQAIWALGNVAGDSTDYRD 205
AL ++ E ++V + V +QLL + S ++E+A+ L +V +S +
Sbjct: 184 ALESLLGAMQEDEKMVLMPLIGRANVAALVQLLTATSTRIREKAV-NLISVLAESGHCDE 242
Query: 206 YVLQCGAMQPILYLFELNKTSLIRTATWTLSNLCRGKKPQPDWSIVSQALPTLSKLIYSM 265
+++ G + P++ L E A + L ++ + + P + L +
Sbjct: 243 WLISEGVLPPLVRLIESGSLETKEKAAIAIQRLSMTEENAREIAGHGGITPLID-LCKTG 301
Query: 266 DTETLVDACWAISYLSDGPVNSI-QAVVDARIPKRLVELLSHQSTLVQTPAL-RAVGNIV 323
D+ + + A+ +S V+ + Q + + I + ++LL+H L + + N+
Sbjct: 302 DSVSQAASAAALKNMS--AVSELRQLLAEEGIIRVSIDLLNHGILLGSREHMAECLQNLT 359
Query: 324 TGNDLQTQIVINCGALAALRNLLASPKESIRKEACWTISNITAGNTEQIQAVIDANLIPP 383
+D + +++ G + +L L P ++ A + N+ +I + NL+P
Sbjct: 360 AASDALREAIVSEGGVPSLLAYLDGPLP--QQPAVTALRNLIPSVNPEIWVAL--NLLPR 415
Query: 384 LIRLLETAEYKTKKEACWAISNASSGGLHKPEIIRYLVSQGCIKPLCDLLEIADNRIIEV 443
L +L++ ++ A AI + PE R + GCI + LLE N E
Sbjct: 416 LRHVLKSGSLGAQQAAASAICRFACS----PETKRLVGESGCIPEIVKLLESKSNGCREA 471
Query: 444 TLDAIENILKMGEMDREVR 462
AI ++ G + RE++
Sbjct: 472 AAQAIAGLVAEGRIRRELK 490
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.317 0.133 0.379
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,504,106
Number of Sequences: 60738
Number of extensions: 1168087
Number of successful extensions: 4234
Number of sequences better than 1.0e-05: 46
Number of HSP's better than 0.0 without gapping: 31
Number of HSP's successfully gapped in prelim test: 16
Number of HSP's that attempted gapping in prelim test: 3488
Number of HSP's gapped (non-prelim): 103
length of query: 538
length of database: 30,389,216
effective HSP length: 111
effective length of query: 427
effective length of database: 23,647,298
effective search space: 10097396246
effective search space used: 10097396246
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)