ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIV2205 good S KOG4653 Function unknown Uncharacterized conserved protein
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIV2205 750551 747669 -961
(961 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YMR185w [S] KOG4653 Uncharacterized conserved protein 634 0.0
SPBC20F10.08c [S] KOG4653 Uncharacterized conserved protein 81 9e-15
Hs16164755 [S] KOG4653 Uncharacterized conserved protein 70 1e-11
>YMR185w [S] KOG4653 Uncharacterized conserved protein
Length = 981
Score = 634 bits (1636), Expect = 0.0
Identities = 362/989 (36%), Positives = 590/989 (59%), Gaps = 65/989 (6%)
Query: 7 EVLSRKLDFVSDTPIDAFFQELDE-FLKPIKH------NDDIGDIYESLNLSNK-ELIEK 58
++L+ + T +D FF++LD+ + PI + IY++L SN E +
Sbjct: 13 DILNTRPKLTKKTALDVFFEDLDDNVITPINEYVLDSGSSSSSSIYQALKCSNNNEFVAV 72
Query: 59 LAKFLTRLCSLVAEKQ----QENADIIPISLHDMKDFDTLINLLVIHGITANLPIDIGIP 114
L + L V E+Q + +D++PISLHDMK D LINLL+IHGI ANL + IP
Sbjct: 73 LLQKFQNLHIHVLEQQRRLIESKSDLLPISLHDMKYVDELINLLIIHGIDANLSPTMKIP 132
Query: 115 IEQRRLDVFKEENKL--YKVPNGKIADVETLKVALLAFESIFLHTPENNYVRKIILKGGP 172
+ +R++ FK+ K Y+ P + +TL + F ++ ++Y+R+II KG
Sbjct: 133 FDSKRINTFKKGQKSAEYETPRWHTINNDTLSQVITVFYNVLTSERSSDYLREIISKGS- 191
Query: 173 GYSDTMIGYMALMCTTGNAAFEEKLRKMETIKDTYSLFEIYSLLLSTIKNDKAKAWPLNR 232
Y++ ++G + L N + + +E ++TY+LF +Y+LL+ TI+++K + L++
Sbjct: 192 AYANILLGLIVLHLQLPNRYSSQMITNLEDTQETYTLFGVYTLLVETIQDEKVREPILSK 251
Query: 233 LSLLVIERSD-GLISLIDFVIGLREDVQVDTSKFERVNQIVTSKPRSISSVEYFDKLFVQ 291
L+ L + R + GLISLIDFV+G+R+ +D KF R+ QI+ SKP+++++++Y +LF Q
Sbjct: 252 LTTLTLRRPENGLISLIDFVLGVRDAEDIDIEKFNRIYQILMSKPKTMTNLQYLTELFKQ 311
Query: 292 IYEGLTHIDKPILVSCLNGLVTAFYLKNKRIVKDFLFSKIYGILYNLDSKDISVKELNDM 351
IY+GLT +++PILV+CLNGL+ FYL+NKRIV DFLF K+ I++N D + KELND+
Sbjct: 312 IYDGLTFVNRPILVTCLNGLILKFYLRNKRIVNDFLFKKVRSIIFNSPLTDHTAKELNDV 371
Query: 352 INVLISLERTPYVEVINEMIL------GHNNGQSFYLNLWIYSMFLKNHQKI-------- 397
INVLISL + +++N+++ G GQ F+L +WIY++FLK +QK+
Sbjct: 372 INVLISLSKNSSSDLLNDLVTSCPDEDGTTPGQ-FFLYVWIYALFLKKNQKLDPLEINKL 430
Query: 398 ------------APDGAKDHYYNIILGLIKTYMVITEGYKYLHVILLNMVNYDHDSWEYK 445
P+ + YY ++L L+K+ +VITE ++YL+V+ LN++N++H+ W+Y
Sbjct: 431 SISDNKSTDSIHFPEQSSSKYYEVVLSLLKSLIVITENFQYLNVLSLNLLNFEHEKWKYL 490
Query: 446 IDLETHLAYITVKEQRISEDLGIGKLSVEEETTKRFQKLFMDIDPAVELFIELLARIDDQ 505
IDL+T L YI+VK ++E L K S + ++ Q D+D ++ELF+E L ++D+
Sbjct: 491 IDLDTQLPYISVKNTDMAE-LFFEKGSKNSQISEFLQ----DMDLSIELFMEFLVLLNDE 545
Query: 506 QVNKSIFSAVINNWLMQEPRNSSESNQSLNFVNDERNNSFADSLQSMIFLKVLEKMNEVF 565
+ +K++F ++ W+ ++ S+ N S D+ ++ LK+LE MN F
Sbjct: 546 EQSKTLFLDILKRWVHHTKKSEKRSSD-----NHSGMPSVTDNALILMDLKLLECMNNRF 600
Query: 566 KSNMLAEPADLLVIILQILDFTRDSKEISVXXXXXXXXXXXAANLTNFTENNDGDMIIND 625
K+ ++ +P D+L++I Q++D ++ E T + N+ +
Sbjct: 601 KTKIVNKPKDVLIVIDQLIDVVQEKDETIQEVEADSDDEVEEGEETEELDPNE------N 654
Query: 626 NTLEVALKLINSIIPTFHSAYSPKEKELLSSIQKKIEPF-VSRDDCKELYDQISDVLLL- 683
++ ++ L+L+++++ S+ + +L SI +K++ F + + L I ++L+
Sbjct: 655 SSYKIILQLLSTVLSESSSSILLQNSYILKSISRKLQSFNTNASEIDALLASIDNILING 714
Query: 684 PTSQAEANSSNEQDKALLKKALTNVNDPLVPIRAHGLLQLRQLIEKKSPLIDVKKVFAIH 743
T++ N E D+ L KA+T+++DPLVPI+++GL +LR L EKKSP+I ++KV IH
Sbjct: 715 HTTERNDNIEIEMDEERLDKAITSLHDPLVPIKSYGLTELRHLAEKKSPVISLEKVLQIH 774
Query: 744 ITQLHDQDAFIYLNVIRGLGVLVQFAPNETLDLLLQFYRACRNKNSVDDILKVGEVFIHY 803
+ L + D FIYLNVI+GL L + P L LL +FY + KN +DD+LKVGEVFI+Y
Sbjct: 775 LDYLKNMDPFIYLNVIKGLTTLCELEPETILPLLAEFYANKKKKNRLDDVLKVGEVFINY 834
Query: 804 VSVQGKSFSGPKAAKLIEVCLENIRAKDQ--LDNRIRMSSMSILGQCLESNALGIRGLIA 861
+ Q + F G A +I+ CL +R D LDNR RMSSMSILG CL+ NA G+ I
Sbjct: 835 IQRQNELFQGKLAYLIIDTCLSIVRPNDSKPLDNRWRMSSMSILGMCLQINARGVSDRIR 894
Query: 862 DILDCAFGILTFETGNDTDDINIKKNSAIMRRSAVHVVYDLMLNSGLNLFPENYPPEKIK 921
D+LDC FGIL E + + K +S +MRRSAVH+++DL+ ++G +L P Y +K+K
Sbjct: 895 DMLDCVFGILQLE--QPQNHLKDKDDSFLMRRSAVHLIHDLLYSTGFDLLPFEYNYDKLK 952
Query: 922 STLEYVATQDDDYLVCEQIKTVSNHLEAL 950
+ L YV QD+DY+VCEQI + L++L
Sbjct: 953 TLLSYVRDQDEDYMVCEQIDKLLTVLDSL 981
>SPBC20F10.08c [S] KOG4653 Uncharacterized conserved protein
Length = 747
Score = 80.9 bits (198), Expect = 9e-15
Identities = 94/367 (25%), Positives = 162/367 (43%), Gaps = 73/367 (19%)
Query: 616 NNDGDMIINDNTLEVALKLINSIIP------------TFHSAYSPKEKELLSSIQKKIEP 663
N D D I ++ L V LIN + T + + +E+L + I
Sbjct: 415 NVDSDEIPSNVMLSVCTNLINEVASQNKYSSTEISQITTNREVEEENEEILLVLLNIISS 474
Query: 664 FVSRDDCKELYDQISDVLLLPTSQAEANSSNEQDKALLKK--------------ALTNVN 709
+ R+ +L + IS LLP + +N SN + L K AL+
Sbjct: 475 VIGRNAELDLENPISS--LLPALEQLSNYSNREISDLAKDVYKTLIQSKDDYSLALSYTQ 532
Query: 710 DPLVPIRAHGLLQLRQLIEKKSPLIDVKKVFAIHITQLHDQDAFIYLNVIRGLGVLVQFA 769
LVP+R G+ LR+LIEKK I+ +V + I L D++++++LNVI + L
Sbjct: 533 SDLVPVRGQGVYMLRKLIEKKDDRINPVRVLHVLINLLRDENSYVHLNVISAVVSLCDKY 592
Query: 770 PNETLDLLLQFYRACRNKNSVDDILKVGEVFIHYVSVQGK---SFSGPKAAKLIEVCLEN 826
+ + LL ++ NK +VD+ L +G+ + QG+ F G ++ + CL
Sbjct: 593 DDSLIRLLKEYTNT--NKFTVDETLLIGQAIYQTMERQGELVAKFYG----QIEQTCLSM 646
Query: 827 IRAKDQLDNRIRMSSMSI---LGQCLESNALGIRGLIADILDCAFGILTFETGNDTDDIN 883
+ + + I++SS++I L Q S+A ++ A IL E G+D
Sbjct: 647 LNNE---NTDIKISSLNIARLLCQMTSSDA---------FIESAKNILILEMGSD----- 689
Query: 884 IKKNSAIMRRSAVHVVYDLMLNSGLNLFPENYPPEKIKSTLEYVATQD-DDYLVCEQIKT 942
+RR+AV +L+S +L P+ + +TL YV + D DD++ +
Sbjct: 690 ----KQFLRRAAVQ-----LLDSCKHL------PDSVITTLSYVGSHDKDDFIKESCLNI 734
Query: 943 VSNHLEA 949
++N +A
Sbjct: 735 LANQADA 741
>Hs16164755 [S] KOG4653 Uncharacterized conserved protein
Length = 1094
Score = 70.5 bits (171), Expect = 1e-11
Identities = 59/221 (26%), Positives = 102/221 (45%), Gaps = 22/221 (9%)
Query: 685 TSQAEANSSNEQDKALLKKALTNVNDPLVPIRAHGLLQLRQLIEKKSP--LIDVKKVFAI 742
TSQ + + EQ L++ L + DP +P RA L L IE++ L +K+ I
Sbjct: 827 TSQKSGSVTTEQ----LQEVLLSAYDPQIPTRAAALRTLSHWIEQREAKALEMQEKLLKI 882
Query: 743 HITQLHDQDAFIYLNVIRGLGVLVQFAPNETLDLLLQFYRACRNKNSVDDILKVGEVFIH 802
+ L +D F+YL+ I+G+ +L P + L LL Y + ++K++ + +KVGEV +
Sbjct: 883 FLENLEHEDTFVYLSAIQGVALLSDVYPEKILPDLLAQYDSSKDKHTPETRMKVGEVLMR 942
Query: 803 YVSVQGKSFSGPKAAKLIEVCLENIRAKDQLDNRIRMSSMSILGQCLESNALGIRGLIAD 862
V G S + LI L +R D R SS++ LG+ + + ++ +
Sbjct: 943 IVRALGDMVSKYR-EPLIHTFLRGVR---DPDGAHRASSLANLGELCQRLDFLLGSVVHE 998
Query: 863 ILDCAFGILTFETGNDTDDINIKKNSAIMRRSAVHVVYDLM 903
+ C + + +RR+A+HVV L+
Sbjct: 999 VTACLIAVAKTD------------GEVQVRRAAIHVVVLLL 1027
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.320 0.138 0.384
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 54,701,192
Number of Sequences: 60738
Number of extensions: 2370864
Number of successful extensions: 6811
Number of sequences better than 1.0e-05: 3
Number of HSP's better than 0.0 without gapping: 1
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 6795
Number of HSP's gapped (non-prelim): 5
length of query: 961
length of database: 30,389,216
effective HSP length: 116
effective length of query: 845
effective length of database: 23,343,608
effective search space: 19725348760
effective search space used: 19725348760
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)