ORF      STATUS       Function Best COG  Functional category                                          Pathways and functional systems
r_klactIV2293   suspect: LH   OT    KOG3986  Posttranslational modification, protein turnover, chaperones   Protein phosphatase, regulatory subunit PPP1R3C/D
r_klactIV2293   suspect: LH   OT    KOG3986  Signal transduction mechanisms                                 Protein phosphatase, regulatory subunit PPP1R3C/D

BLASTP 2.2.3 [May-13-2002]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= r_klactIV2293 778094 775851 -748 
         (748 letters)

Database: KOG eukaryal database 04/03 
           60,738 sequences; 30,389,216 total letters

Searching..................................................done

Color Key for Alignment Scores:   


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

YOR178c [OT] KOG3986 Protein phosphatase regulatory subunit PPP1...   162   2e-39
YLR273c [OT] KOG3986 Protein phosphatase regulatory subunit PPP1...   111   4e-24

>YOR178c [OT] KOG3986 Protein phosphatase regulatory subunit PPP1R3C/D
          Length = 793

 Score =  162 bits (410), Expect = 2e-39
 Identities = 109/319 (34%), Positives = 152/319 (47%), Gaps = 41/319 (12%)

Query: 376 KFRMNGSNDTMTDYDXXXXXXXXX-KENINHQNGFNFNFNTSPTK--------------- 419
           KFR   S + M   D           E+IN Q  + + +N+  T+               
Sbjct: 137 KFRYMNSLNNMFKLDLYDSEDEDDIDEHINSQAEYGYTYNSLSTRGKTSENKSATSSLAT 196

Query: 420 DPIQIKSWILKGTNIKKFYP---------TSLDINQDLSKYLQGNNIKLHECNSLQLSQG 470
               I  W L  T++  F           ++ D+   L+KYL G N+KLH    L     
Sbjct: 197 QATNICDWKLHCTDLVPFKIAPPLFTKTLSASDLQGQLTKYLNGQNVKLHSLTQLGDDSS 256

Query: 471 KLTGLIYVNNLSFEKFIEIKFSFNGWKDIHYVTANFKRTITDTVDEFQFLINLSSFVYFL 530
           K+TGL+YV NLSFEK++EIKF+FN W+DIHYVTANF RTI   VDEF+F I+L+S  Y L
Sbjct: 257 KITGLVYVKNLSFEKYLEIKFTFNSWRDIHYVTANFNRTINSNVDEFKFTIDLNSLKYIL 316

Query: 531 KVKNLILF--NSLISPLTIQLCCRYDVNGETXXXXXXXXXXQVSLDAITNLKQKSKKKSN 588
            +K +I    N+   PL I+LCCRYDVN ET           + +   T  K+  + K  
Sbjct: 317 LIKRIITMEKNTSSCPLNIELCCRYDVNNETYYDNNNGKNYHLFM---TTFKKGGETKEK 373

Query: 589 RHXXXXXXXXXXXXXXXDNFTTDGNYKFASLSPVPSSVDHTKLVPPKLGRRFSEDTDFFN 648
                                     +F S +P  S     + +P    R+FSEDTD++N
Sbjct: 374 IPVVVEPASQTDAAMSPKEMKA----RFVSSNPTLS-----RFLPQ--SRKFSEDTDYYN 422

Query: 649 SSPLKNVSPNYTTTPLNQK 667
           +SPLK++  N TT+ +  K
Sbjct: 423 TSPLKHLYHNDTTSWVKPK 441


>YLR273c [OT] KOG3986 Protein phosphatase regulatory subunit PPP1R3C/D
          Length = 648

 Score =  111 bits (278), Expect = 4e-24
 Identities = 87/263 (33%), Positives = 125/263 (47%), Gaps = 50/263 (19%)

Query: 419 KDPIQIKSWILKGTNIKKF---YPTSLDINQD-LSKYLQGNNIKLHECNSLQLSQG---- 470
           ++   +  W L   N+  F   Y   +   +D + KYL G NIK+H   SL+LS      
Sbjct: 156 EETFDMADWKLVSNNLNPFKSDYKVDVTGLEDKIFKYLNGQNIKVH---SLELSDPVSYE 212

Query: 471 ----------KLTGLIYVNNLSFEKFIEIKFSFNGWKDIHYVTANFKRTITDTVDEFQFL 520
                     ++ GLI+VNNL+FEK IEIKF+ N W DIHY+ A++ +++T  VDEF+F+
Sbjct: 213 DICSNNFGNCQIWGLIFVNNLNFEKKIEIKFTLNNWADIHYINAHYNKSVTPHVDEFKFI 272

Query: 521 INLSSFVYFLKVKNLILFN----SLISPLTIQLCCRYDVNGETXXXXXXXXXXQ-----V 571
           I++S+    L  KNLI  N         L +Q CCRYDVNG            +     +
Sbjct: 273 IDISALKLNLISKNLIYTNFFERKTTCLLNLQFCCRYDVNGFEYRSFYDNNDYKNYEITI 332

Query: 572 SLDAITNLKQKSKKKSNRHXXXXXXXXXXXXXXXDNFTTDGNYKFASLSPVPSSVDHTKL 631
           SL AI NL +     S                   N     +   AS + V  S ++   
Sbjct: 333 SLSAI-NLNRAVSNSS-----------------IFNSNLGPSKMGASNAEVTMSKNNENS 374

Query: 632 VPPKLGRRFSEDTDFFNSSPLKN 654
             P   R+F +DTD++N SPLK+
Sbjct: 375 KKPL--RKFIKDTDYYNDSPLKH 395


  Database: KOG eukaryal database 04/03
    Posted date:  Apr 14, 2003  1:07 PM
  Number of letters in database: 30,389,216
  Number of sequences in database:  60,738
  
Lambda     K      H
   0.314    0.131    0.380 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 31,056,392
Number of Sequences: 60738
Number of extensions: 1049981
Number of successful extensions: 1618
Number of sequences better than 1.0e-05: 2
Number of HSP's better than  0.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 1609
Number of HSP's gapped (non-prelim): 6
length of query: 748
length of database: 30,389,216
effective HSP length: 114
effective length of query: 634
effective length of database: 23,465,084
effective search space: 14876863256
effective search space used: 14876863256
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)