ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIV2325 check: MH T KOG0585 Signal transduction mechanisms Ca2+/calmodulin-dependent protein kinase kinase beta and related serine/threonine protein kinases
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIV2325 791705 788568 -1046
(1046 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YER129w [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kin... 543 e-154
YGL179c [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kin... 301 4e-81
SPCC297.03 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase ... 269 2e-71
Hs14150045 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase ... 171 7e-42
CE01146 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kin... 163 1e-39
Hs17933758 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase ... 156 2e-37
At5g60550 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase k... 153 2e-36
At3g45240 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase k... 145 3e-34
7289880 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kin... 138 4e-32
YKL048c [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kin... 134 6e-31
Hs7661974 [T] KOG0583 Serine/threonine protein kinase 127 7e-29
Hs4507271 [T] KOG0583 Serine/threonine protein kinase 126 2e-28
7299793 [T] KOG0583 Serine/threonine protein kinase 123 1e-27
At5g45820 [T] KOG0583 Serine/threonine protein kinase 121 5e-27
At2g34180 [T] KOG0583 Serine/threonine protein kinase 121 7e-27
CE28218 [D] KOG0588 Serine/threonine protein kinase 120 8e-27
At5g45810 [T] KOG0583 Serine/threonine protein kinase 120 1e-26
Hs20545245 [D] KOG0588 Serine/threonine protein kinase 119 2e-26
Hs7662170 [R] KOG0611 Predicted serine/threonine protein kinase 119 3e-26
At4g18700 [T] KOG0583 Serine/threonine protein kinase 119 3e-26
At3g01090 [T] KOG0583 Serine/threonine protein kinase 119 3e-26
At1g29230 [T] KOG0583 Serine/threonine protein kinase 119 3e-26
At5g10930 [T] KOG0583 Serine/threonine protein kinase 118 4e-26
At3g29160 [T] KOG0583 Serine/threonine protein kinase 118 4e-26
At1g01140 [T] KOG0583 Serine/threonine protein kinase 118 4e-26
At5g39440 [T] KOG0583 Serine/threonine protein kinase 117 7e-26
At5g25110 [T] KOG0583 Serine/threonine protein kinase 117 7e-26
At2g30360 [T] KOG0583 Serine/threonine protein kinase 117 1e-25
YDR507c [D] KOG0588 Serine/threonine protein kinase 116 2e-25
CE27410 [T] KOG0583 Serine/threonine protein kinase 116 2e-25
At4g24400 [T] KOG0583 Serine/threonine protein kinase 116 2e-25
At5g01810 [T] KOG0583 Serine/threonine protein kinase 115 4e-25
7294217 [D] KOG0588 Serine/threonine protein kinase 115 4e-25
At2g25090 [T] KOG0583 Serine/threonine protein kinase 114 8e-25
Hs5453964 [T] KOG0583 Serine/threonine protein kinase 114 1e-24
CE17284 [T] KOG0583 Serine/threonine protein kinase 114 1e-24
CE27768 [R] KOG0586 Serine/threonine protein kinase 113 1e-24
CE23838 [R] KOG0586 Serine/threonine protein kinase 113 1e-24
At2g26980 [T] KOG0583 Serine/threonine protein kinase 113 1e-24
At1g30270 [T] KOG0583 Serine/threonine protein kinase 113 1e-24
At4g30960 [T] KOG0583 Serine/threonine protein kinase 113 2e-24
7290150 [T] KOG0583 Serine/threonine protein kinase 112 4e-24
Hs9845489 [R] KOG0586 Serine/threonine protein kinase 111 7e-24
Hs9845487 [R] KOG0586 Serine/threonine protein kinase 111 7e-24
Hs22062450 [R] KOG0586 Serine/threonine protein kinase 111 7e-24
Hs13899225 [R] KOG0586 Serine/threonine protein kinase 111 7e-24
At4g14580 [T] KOG0583 Serine/threonine protein kinase 110 9e-24
Hs13569922 [R] KOG0611 Predicted serine/threonine protein kinase 110 1e-23
At5g35410 [T] KOG0583 Serine/threonine protein kinase 110 1e-23
SPCC74.03c [T] KOG0583 Serine/threonine protein kinase 109 2e-23
HsM4505103 [R] KOG0586 Serine/threonine protein kinase 109 2e-23
CE07458 [T] KOG0583 Serine/threonine protein kinase 109 2e-23
At5g58380 [T] KOG0583 Serine/threonine protein kinase 109 3e-23
YCL024w [T] KOG0583 Serine/threonine protein kinase 108 3e-23
At5g07070 [T] KOG0583 Serine/threonine protein kinase 108 3e-23
At3g23000 [T] KOG0583 Serine/threonine protein kinase 108 3e-23
7302570 [R] KOG0586 Serine/threonine protein kinase 108 4e-23
7299437 [R] KOG0586 Serine/threonine protein kinase 108 4e-23
Hs8923922 [R] KOG0586 Serine/threonine protein kinase 107 7e-23
CE28643 [T] KOG0583 Serine/threonine protein kinase 107 1e-22
Hs21361133 [R] KOG0586 Serine/threonine protein kinase 106 2e-22
7290249 [R] KOG0586 Serine/threonine protein kinase 106 2e-22
7302464 [R] KOG0586 Serine/threonine protein kinase 105 3e-22
At1g48260 [T] KOG0583 Serine/threonine protein kinase 105 4e-22
At3g17510 [T] KOG0583 Serine/threonine protein kinase 104 6e-22
Hs4502803 [D] KOG0590 Checkpoint kinase and related serine/threo... 104 8e-22
At5g01820 [T] KOG0583 Serine/threonine protein kinase 104 8e-22
YLR096w [T] KOG0583 Serine/threonine protein kinase 103 1e-21
Hs14770402 [R] KOG0586 Serine/threonine protein kinase 103 1e-21
SPCC18B5.11c [D] KOG0615 Serine/threonine protein kinase Chk2 an... 103 2e-21
Hs14670383 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 103 2e-21
YKL101w [D] KOG0588 Serine/threonine protein kinase 102 2e-21
At5g57630 [T] KOG0583 Serine/threonine protein kinase 102 2e-21
YDR477w [T] KOG0583 Serine/threonine protein kinase 102 3e-21
At2g38490 [T] KOG0583 Serine/threonine protein kinase 102 3e-21
7299438 [R] KOG0586 Serine/threonine protein kinase 102 3e-21
Hs5453966 [T] KOG0583 Serine/threonine protein kinase 102 4e-21
Hs20479818 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 101 7e-21
7304283 [Z] KOG0613 Projectin/twitchin and related proteins 101 7e-21
At5g08590 [T] KOG0583 Serine/threonine protein kinase 100 9e-21
YDR122w [T] KOG0583 Serine/threonine protein kinase 100 1e-20
7299322 [R] KOG0611 Predicted serine/threonine protein kinase 100 1e-20
CE07599 [T] KOG0576 Mitogen-activated protein kinase kinase kina... 100 2e-20
At5g63650 [T] KOG0583 Serine/threonine protein kinase 99 3e-20
HsM4759010 [T] KOG0576 Mitogen-activated protein kinase kinase k... 98 6e-20
Hs22035600 [T] KOG0576 Mitogen-activated protein kinase kinase k... 98 6e-20
Hs20545357 [T] KOG0583 Serine/threonine protein kinase 98 6e-20
7303211 [T] KOG4717 Serine/threonine protein kinase 98 6e-20
At1g69220 [T] KOG0576 Mitogen-activated protein kinase kinase ki... 98 8e-20
SPBC12D12.04c [T] KOG0694 Serine/threonine protein kinase 97 1e-19
CE28479 [T] KOG0583 Serine/threonine protein kinase 97 1e-19
7298652 [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 97 1e-19
YPL153c [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 97 2e-19
Hs7706059 [R] KOG0593 Predicted protein kinase KKIAMRE 97 2e-19
CE09360 [Z] KOG0613 Projectin/twitchin and related proteins 97 2e-19
At1g78290 [T] KOG0583 Serine/threonine protein kinase 97 2e-19
At1g12680 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 97 2e-19
Hs4826684_1 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase... 97 2e-19
Hs9966875 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 96 2e-19
Hs4826878 [T] KOG0582 Ste20-like serine/threonine protein kinase 96 2e-19
YPL203w [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 96 3e-19
Hs14589909 [T] KOG0576 Mitogen-activated protein kinase kinase k... 96 3e-19
YAR019c [T] KOG0198 MEKK and related serine/threonine protein ki... 96 4e-19
Hs5454096 [T] KOG0574 STE20-like serine/threonine kinase MST 96 4e-19
At5g04510 [T] KOG0592 3-phosphoinositide-dependent protein kinas... 96 4e-19
YPL141c [T] KOG0583 Serine/threonine protein kinase 95 5e-19
Hs15451902 [T] KOG0576 Mitogen-activated protein kinase kinase k... 95 5e-19
CE26793_1 [R] KOG0611 Predicted serine/threonine protein kinase 95 5e-19
YOR233w [T] KOG0583 Serine/threonine protein kinase 95 7e-19
Hs14149671 [TR] KOG0606 Microtubule-associated serine/threonine ... 95 7e-19
CE25046 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 95 7e-19
7297080 [T] KOG0583 Serine/threonine protein kinase 95 7e-19
At4g33950 [T] KOG0583 Serine/threonine protein kinase 94 9e-19
At4g32830 [D] KOG0580 Serine/threonine protein kinase 94 9e-19
At1g48490 [TR] KOG0606 Microtubule-associated serine/threonine k... 94 9e-19
7302511 [T] KOG0576 Mitogen-activated protein kinase kinase kina... 94 9e-19
Hs7657214 [T] KOG0583 Serine/threonine protein kinase 94 1e-18
Hs4502553 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 94 1e-18
At3g10540 [T] KOG0592 3-phosphoinositide-dependent protein kinas... 94 1e-18
At2g45490 [D] KOG0580 Serine/threonine protein kinase 94 1e-18
At2g25880 [D] KOG0580 Serine/threonine protein kinase 94 1e-18
Hs6005850 [D] KOG0615 Serine/threonine protein kinase Chk2 and r... 94 1e-18
Hs14196445 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 94 1e-18
CE28273 [T] KOG0587 Traf2- and Nck-interacting kinase and relate... 94 1e-18
CE25673 [T] KOG0587 Traf2- and Nck-interacting kinase and relate... 94 1e-18
CE25672 [T] KOG0587 Traf2- and Nck-interacting kinase and relate... 94 1e-18
At1g60940 [T] KOG0583 Serine/threonine protein kinase 94 1e-18
At1g50230 [R] KOG0597 Serine-threonine protein kinase FUSED 94 1e-18
7290147 [T] KOG0583 Serine/threonine protein kinase 94 1e-18
Hs7661994 [T] KOG0579 Ste20-like serine/threonine protein kinase 93 2e-18
Hs4759178 [D] KOG0580 Serine/threonine protein kinase 93 2e-18
At5g66880 [T] KOG0583 Serine/threonine protein kinase 93 2e-18
CE16081 [T] KOG0583 Serine/threonine protein kinase 93 2e-18
YCR091w [R] KOG0610 Putative serine/threonine protein kinase 92 3e-18
At1g12580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 92 3e-18
YKL166c [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 92 4e-18
YDR523c [T] KOG0201 Serine/threonine protein kinase 92 4e-18
Hs14141724 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase ... 92 4e-18
CE28059 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 92 4e-18
7294265 [TR] KOG0606 Microtubule-associated serine/threonine kin... 92 4e-18
HsM5454174 [T] KOG0201 Serine/threonine protein kinase 92 6e-18
Hs21361358 [T] KOG0201 Serine/threonine protein kinase 92 6e-18
Hs17455844 [TR] KOG0606 Microtubule-associated serine/threonine ... 92 6e-18
CE28057 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 92 6e-18
CE28054 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 92 6e-18
CE00847 [T] KOG0583 Serine/threonine protein kinase 92 6e-18
Hs16950621 [Z] KOG0613 Projectin/twitchin and related proteins 91 7e-18
Hs16950613 [Z] KOG0613 Projectin/twitchin and related proteins 91 7e-18
Hs16950611 [Z] KOG0613 Projectin/twitchin and related proteins 91 7e-18
Hs16950601 [Z] KOG0613 Projectin/twitchin and related proteins 91 7e-18
CE27965 [T] KOG0574 STE20-like serine/threonine kinase MST 91 7e-18
CE27726 [T] KOG0574 STE20-like serine/threonine kinase MST 91 7e-18
CE27082 [T] KOG0574 STE20-like serine/threonine kinase MST 91 7e-18
CE07064 [T] KOG0574 STE20-like serine/threonine kinase MST 91 7e-18
7299536 [D] KOG0580 Serine/threonine protein kinase 91 7e-18
Hs5454094 [T] KOG0574 STE20-like serine/threonine kinase MST 91 9e-18
Hs16178962 [T] KOG0574 STE20-like serine/threonine kinase MST 91 9e-18
CE28061 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 91 9e-18
CE28060 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 91 9e-18
CE28058 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 91 9e-18
CE28056 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 91 9e-18
CE28055 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 91 9e-18
CE28053 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 91 9e-18
CE28051 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 91 9e-18
At3g50500 [T] KOG0583 Serine/threonine protein kinase 91 9e-18
At3g07980 [T] KOG0198 MEKK and related serine/threonine protein ... 91 9e-18
YPL150w [T] KOG0583 Serine/threonine protein kinase 91 1e-17
CE14798 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 91 1e-17
7304358 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 91 1e-17
7298323 [D] KOG0590 Checkpoint kinase and related serine/threoni... 90 2e-17
Hs7657335 [T] KOG0587 Traf2- and Nck-interacting kinase and rela... 90 2e-17
7296128 [T] KOG0583 Serine/threonine protein kinase 90 2e-17
SPAC17G8.14c [T] KOG0694 Serine/threonine protein kinase 89 3e-17
Hs4507273 [D] KOG0580 Serine/threonine protein kinase 89 3e-17
CE12518 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 89 3e-17
YJL164c [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 89 4e-17
YBL105c [T] KOG0694 Serine/threonine protein kinase 89 4e-17
SPBC4F6.06 [T] KOG0583 Serine/threonine protein kinase 89 4e-17
Hs4505695 [T] KOG0592 3-phosphoinositide-dependent protein kinas... 89 4e-17
CE21025 [D] KOG0580 Serine/threonine protein kinase 89 4e-17
CE18454 [T] KOG4717 Serine/threonine protein kinase 89 4e-17
7300106 [T] KOG0690 Serine/threonine protein kinase 89 4e-17
7293601 [T] KOG0577 Serine/threonine protein kinase 89 4e-17
Hs20428779_1 [T] KOG0587 Traf2- and Nck-interacting kinase and r... 89 4e-17
HsM4758524 [T] KOG0587 Traf2- and Nck-interacting kinase and rel... 89 5e-17
Hs22035606 [T] KOG0587 Traf2- and Nck-interacting kinase and rel... 89 5e-17
Hs22035604 [T] KOG0587 Traf2- and Nck-interacting kinase and rel... 89 5e-17
Hs22035602 [T] KOG0587 Traf2- and Nck-interacting kinase and rel... 89 5e-17
Hs21361643 [T] KOG4717 Serine/threonine protein kinase 89 5e-17
Hs20070158 [T] KOG0201 Serine/threonine protein kinase 89 5e-17
SPCC320.12c [D] KOG0580 Serine/threonine protein kinase 88 6e-17
At5g50860 [D] KOG0600 Cdc2-related protein kinase 88 6e-17
7292249 [T] KOG0587 Traf2- and Nck-interacting kinase and relate... 88 6e-17
Hs4557511 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 88 8e-17
Hs20543401 [TR] KOG0606 Microtubule-associated serine/threonine ... 88 8e-17
7296450 [D] KOG0575 Polo-like serine/threonine protein kinase 88 8e-17
Hs4502567_1 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase... 88 8e-17
SPAC890.03 [T] KOG0583 Serine/threonine protein kinase 87 1e-16
Hs7706401 [T] KOG0577 Serine/threonine protein kinase 87 1e-16
Hs6005810 [T] KOG0576 Mitogen-activated protein kinase kinase ki... 87 1e-16
Hs4759208 [T] KOG0577 Serine/threonine protein kinase 87 1e-16
Hs22057171 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 87 1e-16
CE26076 [D] KOG0590 Checkpoint kinase and related serine/threoni... 87 1e-16
CE04603 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 87 1e-16
At1g03740 [D] KOG0600 Cdc2-related protein kinase 87 1e-16
Hs5174701 [T] KOG0579 Ste20-like serine/threonine protein kinase 87 1e-16
At3g17850 [TR] KOG0606 Microtubule-associated serine/threonine k... 87 1e-16
7303804 [R] KOG0663 Protein kinase PITSLRE and related kinases 87 1e-16
7292679 [G] KOG0599 Phosphorylase kinase gamma subunit 87 1e-16
Hs4507275 [D] KOG0580 Serine/threonine protein kinase 87 2e-16
Hs14776113 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 87 2e-16
At3g13530 [T] KOG0198 MEKK and related serine/threonine protein ... 87 2e-16
At2g31500 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 87 2e-16
At1g54610 [D] KOG0600 Cdc2-related protein kinase 87 2e-16
At1g10940 [T] KOG0583 Serine/threonine protein kinase 87 2e-16
CE28674 [T] KOG0201 Serine/threonine protein kinase 86 2e-16
CE07510 [T] KOG0201 Serine/threonine protein kinase 86 2e-16
At4g04720 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 86 2e-16
7293666 [D] KOG0575 Polo-like serine/threonine protein kinase 86 2e-16
7293249 [T] KOG0612 Rho-associated coiled-coil containing protei... 86 2e-16
SPBC106.10 [T] KOG0616 cAMP-dependent protein kinase catalytic s... 86 3e-16
SPAC1F3.02c [T] KOG0198 MEKK and related serine/threonine protei... 86 3e-16
Hs15011880 [T] KOG0201 Serine/threonine protein kinase 86 3e-16
At2g23030 [T] KOG0583 Serine/threonine protein kinase 86 3e-16
7297542 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 86 3e-16
7296166 [T] KOG0614 cGMP-dependent protein kinase 86 3e-16
HsM4507279 [D] KOG0580 Serine/threonine protein kinase 86 4e-16
CE27573 [T] KOG0198 MEKK and related serine/threonine protein ki... 86 4e-16
CE07737 [T] KOG0198 MEKK and related serine/threonine protein ki... 86 4e-16
Hs20127418 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase ... 85 5e-16
At1g09000 [T] KOG0198 MEKK and related serine/threonine protein ... 85 5e-16
7297009 [R] KOG0593 Predicted protein kinase KKIAMRE 85 5e-16
Hs7661946 [T] KOG4250 TANK binding protein kinase TBK1 85 7e-16
Hs7019543 [T] KOG0582 Ste20-like serine/threonine protein kinase 85 7e-16
CE26212 [T] KOG0582 Ste20-like serine/threonine protein kinase 85 7e-16
At3g49370 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 85 7e-16
At1g50700 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 85 7e-16
7300224 [T] KOG0201 Serine/threonine protein kinase 85 7e-16
YOL113w [T] KOG0578 p21-activated serine/threonine protein kinase 84 9e-16
HsM8923212 [T] KOG4717 Serine/threonine protein kinase 84 9e-16
CE07285 [D] KOG0575 Polo-like serine/threonine protein kinase 84 9e-16
At5g62310 [TR] KOG0606 Microtubule-associated serine/threonine k... 84 9e-16
SPAC23H4.02 [T] KOG0583 Serine/threonine protein kinase 84 1e-15
Hs5730055 [D] KOG0575 Polo-like serine/threonine protein kinase 84 1e-15
Hs4506057 [T] KOG0616 cAMP-dependent protein kinase catalytic su... 84 1e-15
Hs14042966 [T] KOG0583 Serine/threonine protein kinase 84 1e-15
CE20167 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD a... 84 1e-15
CE18699 [T] KOG0694 Serine/threonine protein kinase 84 1e-15
At5g24430 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 84 1e-15
At5g20930 [T] KOG1151 Tousled-like protein kinase 84 1e-15
7303019 [Z] KOG0613 Projectin/twitchin and related proteins 84 1e-15
7297776 [D] KOG0580 Serine/threonine protein kinase 84 1e-15
CE18058_1 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 84 1e-15
SPAC2C4.14c [T] KOG0201 Serine/threonine protein kinase 84 2e-15
Hs7706286 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase E... 84 2e-15
Hs5453974 [T] KOG0694 Serine/threonine protein kinase 84 2e-15
Hs16507245 [T] KOG0583 Serine/threonine protein kinase 84 2e-15
CE03979 [T] KOG0614 cGMP-dependent protein kinase 84 2e-15
At1g73500 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 84 2e-15
SPCC1919.01 [T] KOG0583 Serine/threonine protein kinase 83 2e-15
Hs18552621 [R] KOG0597 Serine-threonine protein kinase FUSED 83 2e-15
Hs14042947 [T] KOG0583 Serine/threonine protein kinase 83 2e-15
At2g38910 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 83 2e-15
At2g37840 [OUT] KOG0595 Serine/threonine-protein kinase involved... 83 2e-15
At1g18890 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 83 2e-15
YNL183c [D] KOG0590 Checkpoint kinase and related serine/threoni... 83 3e-15
YDL101c [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 83 3e-15
Hs5032091 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 83 3e-15
Hs22043888 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 83 3e-15
Hs15619015 [T] KOG0616 cAMP-dependent protein kinase catalytic s... 83 3e-15
Hs14916455 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 83 3e-15
Hs10835242 [T] KOG0614 cGMP-dependent protein kinase 83 3e-15
CE01405 [T] KOG0577 Serine/threonine protein kinase 83 3e-15
At5g44290 [D] KOG0600 Cdc2-related protein kinase 83 3e-15
At4g21940 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 83 3e-15
7292656 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 83 3e-15
YDR466w [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 82 3e-15
YCR008w [D] KOG0590 Checkpoint kinase and related serine/threoni... 82 3e-15
Hs4885549 [T] KOG0690 Serine/threonine protein kinase 82 3e-15
Hs4506055 [T] KOG0616 cAMP-dependent protein kinase catalytic su... 82 3e-15
Hs4502731 [R] KOG0663 Protein kinase PITSLRE and related kinases 82 3e-15
Hs14777335 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 82 3e-15
ECU03g0980 [T] KOG0583 Serine/threonine protein kinase 82 3e-15
At3g51850 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 82 3e-15
Hs8393810_1 [T] KOG0587 Traf2- and Nck-interacting kinase and re... 82 3e-15
Hs20544910_1 [T] KOG0587 Traf2- and Nck-interacting kinase and r... 82 3e-15
HsM4826916 [D] KOG0575 Polo-like serine/threonine protein kinase 82 4e-15
Hs8923754 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 82 4e-15
Hs19923464 [T] KOG0577 Serine/threonine protein kinase 82 4e-15
Hs16950647 [R] KOG0663 Protein kinase PITSLRE and related kinases 82 4e-15
CE21086 [D] KOG0590 Checkpoint kinase and related serine/threoni... 82 4e-15
CE15473 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 82 4e-15
At4g23650 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 82 4e-15
At1g51660 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 82 4e-15
7291778 [T] KOG0579 Ste20-like serine/threonine protein kinase 82 4e-15
SPBC543.07 [T] KOG0581 Mitogen-activated protein kinase kinase (... 82 6e-15
HsM7657627 [D] KOG0575 Polo-like serine/threonine protein kinase 82 6e-15
Hs20986521 [T] KOG0665 Jun-N-terminal kinase (JNK) 82 6e-15
Hs20986519 [T] KOG0665 Jun-N-terminal kinase (JNK) 82 6e-15
CE15475 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 82 6e-15
At3g57530 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 82 6e-15
7301734 [T] KOG0694 Serine/threonine protein kinase 82 6e-15
YAL017w [T] KOG1152 Signal transduction serine/threonine kinase ... 81 7e-15
SPBC1604.14c [T] KOG0578 p21-activated serine/threonine protein ... 81 7e-15
ECU07g0360 [D] KOG0580 Serine/threonine protein kinase 81 7e-15
CE24761 [D] KOG0580 Serine/threonine protein kinase 81 7e-15
At5g63370 [R] KOG0663 Protein kinase PITSLRE and related kinases 81 7e-15
At4g10010 [D] KOG0600 Cdc2-related protein kinase 81 7e-15
At3g21220 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 81 7e-15
At3g06030 [T] KOG0198 MEKK and related serine/threonine protein ... 81 7e-15
At1g71530 [D] KOG0600 Cdc2-related protein kinase 81 7e-15
At1g61950 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 81 7e-15
Hs4885583 [T] KOG0612 Rho-associated coiled-coil containing prot... 81 1e-14
Hs4826948 [T] KOG0616 cAMP-dependent protein kinase catalytic su... 81 1e-14
Hs4506075 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD... 81 1e-14
Hs16936530 [R] KOG0594 Protein kinase PCTAIRE and related kinases 81 1e-14
Hs16936528 [R] KOG0594 Protein kinase PCTAIRE and related kinases 81 1e-14
CE20564 [T] KOG0578 p21-activated serine/threonine protein kinase 81 1e-14
CE05425 [T] KOG0578 p21-activated serine/threonine protein kinase 81 1e-14
CE05274 [T] KOG0690 Serine/threonine protein kinase 81 1e-14
At2g41860 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 81 1e-14
7304311 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 81 1e-14
SPAC9G1.09 [T] KOG0201 Serine/threonine protein kinase 80 1e-14
Hs7662210 [OUT] KOG0595 Serine/threonine-protein kinase involved... 80 1e-14
Hs4505153 [T] KOG0198 MEKK and related serine/threonine protein ... 80 1e-14
Hs21359873 [D] KOG0575 Polo-like serine/threonine protein kinase 80 1e-14
CE26649 [D] KOG0575 Polo-like serine/threonine protein kinase 80 1e-14
At5g39420 [D] KOG0600 Cdc2-related protein kinase 80 1e-14
At4g40010 [T] KOG0583 Serine/threonine protein kinase 80 1e-14
At3g10660 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 80 1e-14
At1g74740 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 80 1e-14
At1g53050 [D] KOG0600 Cdc2-related protein kinase 80 1e-14
7303915 [T] KOG0694 Serine/threonine protein kinase 80 1e-14
7303914 [T] KOG0694 Serine/threonine protein kinase 80 1e-14
YPL140c [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K) 80 2e-14
SPCC70.05c [D] KOG0590 Checkpoint kinase and related serine/thre... 80 2e-14
SPAC2F3.15 [D] KOG0600 Cdc2-related protein kinase 80 2e-14
At1g70430 [T] KOG0582 Ste20-like serine/threonine protein kinase 80 2e-14
At1g53165 [T] KOG0201 Serine/threonine protein kinase 80 2e-14
7290565 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase... 80 2e-14
SPBC17F3.02 [T] KOG0201 Serine/threonine protein kinase 80 2e-14
SPAC23C11.16 [D] KOG0575 Polo-like serine/threonine protein kinase 80 2e-14
Hs4826675 [UT] KOG0662 Cyclin-dependent kinase CDK5 80 2e-14
Hs4557439 [R] KOG0594 Protein kinase PCTAIRE and related kinases 80 2e-14
Hs4506073 [T] KOG0694 Serine/threonine protein kinase 80 2e-14
Hs4505785 [G] KOG0599 Phosphorylase kinase gamma subunit 80 2e-14
Hs19923468 [T] KOG4236 Serine/threonine protein kinase PKC mu/PK... 80 2e-14
Hs16950615 [Z] KOG0613 Projectin/twitchin and related proteins 80 2e-14
Hs14758219 [T] KOG0694 Serine/threonine protein kinase 80 2e-14
At1g33770 [D] KOG0600 Cdc2-related protein kinase 80 2e-14
SPBC21.06c [T] KOG0198 MEKK and related serine/threonine protein... 79 3e-14
Hs16418343 [T] KOG0583 Serine/threonine protein kinase 79 3e-14
Hs10835065 [T] KOG0616 cAMP-dependent protein kinase catalytic s... 79 3e-14
CE29298 [T] KOG0690 Serine/threonine protein kinase 79 3e-14
CE26422 [D] KOG0600 Cdc2-related protein kinase 79 3e-14
CE20493 [TR] KOG0606 Microtubule-associated serine/threonine kin... 79 3e-14
CE18646 [T] KOG0690 Serine/threonine protein kinase 79 3e-14
At5g66850 [T] KOG0198 MEKK and related serine/threonine protein ... 79 3e-14
At5g10270 [D] KOG0600 Cdc2-related protein kinase 79 3e-14
At4g04700 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 79 3e-14
At3g20410 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 79 3e-14
At3g15220 [T] KOG0201 Serine/threonine protein kinase 79 3e-14
At3g05050 [D] KOG0600 Cdc2-related protein kinase 79 3e-14
At1g54960 [T] KOG0198 MEKK and related serine/threonine protein ... 79 3e-14
7302458 [T] KOG0574 STE20-like serine/threonine kinase MST 79 3e-14
YJL095w [T] KOG0198 MEKK and related serine/threonine protein ki... 79 4e-14
SPAC9G1.02 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 an... 79 4e-14
CE27297 [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 79 4e-14
CE21879 [D] KOG0590 Checkpoint kinase and related serine/threoni... 79 4e-14
CE18169 [T] KOG0603 Ribosomal protein S6 kinase 79 4e-14
CE13014 [T] KOG0603 Ribosomal protein S6 kinase 79 4e-14
At3g61960 [OUT] KOG0595 Serine/threonine-protein kinase involved... 79 4e-14
At2g17890 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 79 4e-14
At1g57700 [D] KOG0600 Cdc2-related protein kinase 79 4e-14
YPL209c [D] KOG0580 Serine/threonine protein kinase 79 5e-14
YHL007c [T] KOG0578 p21-activated serine/threonine protein kinase 79 5e-14
HsM5729922 [T] KOG0198 MEKK and related serine/threonine protein... 79 5e-14
Hs4758192 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 79 5e-14
Hs4758016 [D] KOG0575 Polo-like serine/threonine protein kinase 79 5e-14
Hs21361433 [D] KOG0575 Polo-like serine/threonine protein kinase 79 5e-14
CE28251 [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 79 5e-14
At5g64960 [D] KOG0600 Cdc2-related protein kinase 79 5e-14
At1g09600 [D] KOG0600 Cdc2-related protein kinase 79 5e-14
SPAC57A10.02 [D] KOG0588 Serine/threonine protein kinase 78 6e-14
At5g19450 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 78 6e-14
At5g04870 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 78 6e-14
At1g76040 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 78 6e-14
At1g18350 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 78 6e-14
7300773 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase... 78 6e-14
SPBC1D7.05c [T] KOG0198 MEKK and related serine/threonine protei... 78 8e-14
Hs4506095 [T] KOG0665 Jun-N-terminal kinase (JNK) 78 8e-14
Hs4506081 [T] KOG0665 Jun-N-terminal kinase (JNK) 78 8e-14
Hs20986523 [T] KOG0665 Jun-N-terminal kinase (JNK) 78 8e-14
Hs20986510 [T] KOG0665 Jun-N-terminal kinase (JNK) 78 8e-14
Hs20986506 [T] KOG0665 Jun-N-terminal kinase (JNK) 78 8e-14
Hs16950617 [Z] KOG0613 Projectin/twitchin and related proteins 78 8e-14
At3g19100 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 78 8e-14
7297680 [R] KOG0594 Protein kinase PCTAIRE and related kinases 78 8e-14
Hs20070247_2 [RT] KOG0598 Ribosomal protein S6 kinase and relate... 78 8e-14
YOL100w [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 77 1e-13
YBR028c [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 77 1e-13
SPACUNK12.02c [T] KOG0032 Ca2+/calmodulin-dependent protein kina... 77 1e-13
Hs7705551 [T] KOG0661 MAPK related serine/threonine protein kinase 77 1e-13
At5g12180 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 77 1e-13
At2g17290 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 77 1e-13
YOR231w [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K) 77 1e-13
Hs9994197 [T] KOG0607 MAP kinase-interacting kinase and related ... 77 1e-13
Hs7662388 [T] KOG0661 MAPK related serine/threonine protein kinase 77 1e-13
CE22877 [D] KOG0575 Polo-like serine/threonine protein kinase 77 1e-13
CE15612 [T] KOG0690 Serine/threonine protein kinase 77 1e-13
At4g08470 [T] KOG0198 MEKK and related serine/threonine protein ... 77 1e-13
7303051 [UT] KOG0662 Cyclin-dependent kinase CDK5 77 1e-13
YKL139w [D] KOG0600 Cdc2-related protein kinase 77 2e-13
Hs5031689 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD... 77 2e-13
Hs19923407 [D] KOG0591 NIMA (never in mitosis)-related G2-specif... 77 2e-13
CE20636 [D] KOG0590 Checkpoint kinase and related serine/threoni... 77 2e-13
At4g35310 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 77 2e-13
7300149 [T] KOG0578 p21-activated serine/threonine protein kinase 77 2e-13
7299160 [OUT] KOG0595 Serine/threonine-protein kinase involved i... 77 2e-13
YNL298w [T] KOG0578 p21-activated serine/threonine protein kinase 76 2e-13
Hs9910476 [T] KOG0578 p21-activated serine/threonine protein kinase 76 2e-13
Hs4506737 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 76 2e-13
Hs20986501 [T] KOG0660 Mitogen-activated protein kinase 76 2e-13
Hs20986497 [T] KOG0660 Mitogen-activated protein kinase 76 2e-13
Hs20149547 [T] KOG0603 Ribosomal protein S6 kinase 76 2e-13
At4g10730 [T] KOG0582 Ste20-like serine/threonine protein kinase 76 2e-13
At2g46700 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 76 2e-13
At1g18670 [D] KOG0600 Cdc2-related protein kinase 76 2e-13
7296451 [D] KOG0600 Cdc2-related protein kinase 76 2e-13
Hs16357474_1 [T] KOG0612 Rho-associated coiled-coil containing p... 76 2e-13
YGL180w [OUT] KOG0595 Serine/threonine-protein kinase involved i... 76 3e-13
Hs4885563 [T] KOG0694 Serine/threonine protein kinase 76 3e-13
Hs4506739 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 76 3e-13
Hs4505569 [R] KOG0593 Predicted protein kinase KKIAMRE 76 3e-13
Hs4502709 [R] KOG0594 Protein kinase PCTAIRE and related kinases 76 3e-13
Hs21735556 [T] KOG0198 MEKK and related serine/threonine protein... 76 3e-13
Hs10863901 [T] KOG0604 MAP kinase-activated protein kinase 2 76 3e-13
At4g38230 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 76 3e-13
At4g24100 [T] KOG0582 Ste20-like serine/threonine protein kinase 76 3e-13
YOL016c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 75 4e-13
YBR274w [D] KOG0590 Checkpoint kinase and related serine/threoni... 75 4e-13
SPCC16C4.11 [R] KOG0594 Protein kinase PCTAIRE and related kinases 75 4e-13
SPBC16E9.13 [T] KOG0583 Serine/threonine protein kinase 75 4e-13
Hs4759044 [T] KOG0612 Rho-associated coiled-coil containing prot... 75 4e-13
Hs20536595 [T] KOG0612 Rho-associated coiled-coil containing pro... 75 4e-13
Hs20127541 [RT] KOG0598 Ribosomal protein S6 kinase and related ... 75 4e-13
CE21213 [UT] KOG0662 Cyclin-dependent kinase CDK5 75 4e-13
7297611 [T] KOG0614 cGMP-dependent protein kinase 75 4e-13
Hs4759050 [T] KOG0603 Ribosomal protein S6 kinase 75 5e-13
Hs4507831 [OUT] KOG0595 Serine/threonine-protein kinase involved... 75 5e-13
Hs4506529 [T] KOG0986 G protein-coupled receptor kinase 75 5e-13
Hs4506071 [T] KOG0695 Serine/threonine protein kinase 75 5e-13
Hs14993776 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 75 5e-13
Hs11140819 [T] KOG1151 Tousled-like protein kinase 75 5e-13
7290436 [T] KOG1151 Tousled-like protein kinase 75 5e-13
Hs4758128_2 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase... 75 5e-13
SPCC1259.13 [D] KOG0590 Checkpoint kinase and related serine/thr... 75 7e-13
Hs5453882 [G] KOG0599 Phosphorylase kinase gamma subunit 75 7e-13
Hs14728804 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 75 7e-13
SPCC162.10 [RT] KOG0598 Ribosomal protein S6 kinase and related ... 74 9e-13
Hs5453978 [T] KOG0614 cGMP-dependent protein kinase 74 9e-13
Hs19923570 [T] KOG0603 Ribosomal protein S6 kinase 74 9e-13
CE06635 [Z] KOG0613 Projectin/twitchin and related proteins 74 9e-13
CE06634 [Z] KOG0613 Projectin/twitchin and related proteins 74 9e-13
CE05780 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 74 9e-13
CE01761 [R] KOG0663 Protein kinase PITSLRE and related kinases 74 9e-13
At4g22940 [D] KOG0600 Cdc2-related protein kinase 74 9e-13
At2g42630 [T] KOG0192 Tyrosine kinase specific for activated (GT... 74 9e-13
At1g74330 [D] KOG0600 Cdc2-related protein kinase 74 9e-13
At1g49580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 74 9e-13
SPCC576.15c [T] KOG0592 3-phosphoinositide-dependent protein kin... 74 1e-12
HsM20070143 [T] KOG0665 Jun-N-terminal kinase (JNK) 74 1e-12
Hs7705841 [T] KOG1187 Serine/threonine protein kinase 74 1e-12
Hs4507281 [R] KOG0593 Predicted protein kinase KKIAMRE 74 1e-12
Hs21237739 [T] KOG0665 Jun-N-terminal kinase (JNK) 74 1e-12
Hs21237736 [T] KOG0665 Jun-N-terminal kinase (JNK) 74 1e-12
Hs14768528 [T] KOG1187 Serine/threonine protein kinase 74 1e-12
Hs11496279 [T] KOG0661 MAPK related serine/threonine protein kinase 74 1e-12
At5g61350 [T] KOG1187 Serine/threonine protein kinase 74 1e-12
7302908 [R] KOG0594 Protein kinase PCTAIRE and related kinases 74 1e-12
CE02602_1 [T] KOG0660 Mitogen-activated protein kinase 74 1e-12
SPCC63.08c [OUT] KOG0595 Serine/threonine-protein kinase involve... 74 2e-12
Hs4502747 [D] KOG0669 Cyclin T-dependent kinase CDK9 74 2e-12
Hs20143922 [Z] KOG0613 Projectin/twitchin and related proteins 74 2e-12
Hs20143918 [Z] KOG0613 Projectin/twitchin and related proteins 74 2e-12
Hs20143914 [Z] KOG0613 Projectin/twitchin and related proteins 74 2e-12
Hs19747267 [Z] KOG0613 Projectin/twitchin and related proteins 74 2e-12
ECU08g0230 [R] KOG0594 Protein kinase PCTAIRE and related kinases 74 2e-12
CE07905 [T] KOG0579 Ste20-like serine/threonine protein kinase 74 2e-12
At3g48750 [R] KOG0594 Protein kinase PCTAIRE and related kinases 74 2e-12
At2g35890 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 74 2e-12
At1g62400 [T] KOG0192 Tyrosine kinase specific for activated (GT... 74 2e-12
At1g08650 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 74 2e-12
Hs7706549 [D] KOG0600 Cdc2-related protein kinase 73 2e-12
Hs4757868 [T] KOG0193 Serine/threonine protein kinase RAF 73 2e-12
ECU01g0630 [D] KOG0575 Polo-like serine/threonine protein kinase 73 2e-12
CE20258 [R] KOG0593 Predicted protein kinase KKIAMRE 73 2e-12
CE20142 [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 73 2e-12
CE19898 [T] KOG0614 cGMP-dependent protein kinase 73 2e-12
CE19897 [T] KOG0614 cGMP-dependent protein kinase 73 2e-12
>YER129w [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kinase beta
and related serine/threonine protein kinases
Length = 1142
Score = 543 bits (1400), Expect = e-154
Identities = 356/866 (41%), Positives = 489/866 (56%), Gaps = 134/866 (15%)
Query: 58 EKQRQRQLNHPLHQNHIR-------TVLGSHLNSGQRITYGPVKETNTVSLEYDPISKRK 110
E+QR RQLNHP HQ HI T S +SG + VKETN +SL YDP+SKRK
Sbjct: 71 ERQRVRQLNHPQHQQHISSSLAKTPTTTSSFCSSGS--SKNKVKETNRISLTYDPVSKRK 128
Query: 111 VLNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIE 170
VLNTYEII+ELGHGQHGKVKLARD+++KQLVAIKIV+RH+K+ KF K+ + E
Sbjct: 129 VLNTYEIIKELGHGQHGKVKLARDILSKQLVAIKIVDRHEKK--QRKFFTFIKSSKIS-E 185
Query: 171 DEKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKARG 230
++KIKREIAIMKKCHH+HVV+LIEVLDD KSRKIYLVLEYCS+GE+KWCP D +E+ A+G
Sbjct: 186 NDKIKREIAIMKKCHHKHVVQLIEVLDDLKSRKIYLVLEYCSRGEVKWCPPDCMESDAKG 245
Query: 231 PPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXXXXXXX 290
P LLSFQ TREI RGV+LGLEYLH+QGIIHRDIKPANLL+S DG VKISDFGV
Sbjct: 246 PSLLSFQETREILRGVVLGLEYLHYQGIIHRDIKPANLLISGDGTVKISDFGVSLAASST 305
Query: 291 XXXXXXXX---XXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNS--KEPIISFPTDIWAM 345
AKT GTPAFFAPE+CL ED +++L + + ISF DIWA+
Sbjct: 306 NSSDSSESLDELELAKTVGTPAFFAPEMCLGEDAFTRYNLTKENLFRGSCISFMIDIWAV 365
Query: 346 GITLHCLLFGMLPFISDYELELFDKIVNEPLVFEPYQKIEQCQVSQVECKEEYEEAQXXX 405
G+TL+CLLFGMLPF SD+EL+LF+KIVN+PL F +++I+ +VS+V C+EEYE A+
Sbjct: 366 GVTLYCLLFGMLPFFSDFELKLFEKIVNDPLKFPTFKEIQSNKVSKVSCEEEYEMAKDLL 425
Query: 406 XXXXXXXXXXRMAIQDAKKHPWVCWDFNHNDYMSDQEKSLKLIEQSNFHRSPSEQVEQIC 465
RM I KKHP+V WDF+H ++ S L ++ F + ++Q E I
Sbjct: 426 LKLLEKNPQKRMTIPAIKKHPFVSWDFDHVPENDEKLLSSVLEQKLRFQCNQTDQFEPIS 485
Query: 466 ISEHEVDTAVGGIGHKIKNAVGKFLPSTKSNDESNTN----------------SVNEFND 509
IS+HE+ AV G+G KIK +V K +P +D SN N V+E +
Sbjct: 486 ISKHELKNAVSGVGKKIKESVLKSIPLKDPSDLSNKNYLHPTETTRGRGDANVIVSEGSV 545
Query: 510 SGNNKYI---DGCLNSCASYTDNGNLILSEETYISPKDSTGYGNEGTNLVEDSSSVPVHD 566
N K + DGCLN+ + N+ ++++ + S D+ G+
Sbjct: 546 LSNIKELSANDGCLNT----DSDTNININDDDHYSGDDNDGH------------------ 583
Query: 567 VSAREIFQQELQRFDNRRDPDSIVSLPVNSSFASLDSFYIDHYAPRQLSEHSFQGPLAQQ 626
++ RE+ ++EL +FD++ + ++V+LP+NSSFASLDSFYID++A ++ ++
Sbjct: 584 LTKREL-ERELNKFDDKHEAGNMVNLPINSSFASLDSFYIDNFAMARMG-------MSSP 635
Query: 627 QKFEAFDRPPIGPFSKPNSN--GRVPTQTAF-RIPSPNALQLDTLTMGSGISGRNIRSNL 683
+ ++ P P S P+S GR P + PSP L +GR +S
Sbjct: 636 EAGDSVSSVPNLP-SAPSSTRLGRSPVFSGVTNQPSPIRPVLPQQKSSFCATGRYDKS-- 692
Query: 684 HSPILSPTGTLSRRTSNEFPNAALGSRLRKPASLHTYDKNQS-----AFTNPRVPGD--- 735
H+ +L + + ++ P++ G + +L + S T RVP D
Sbjct: 693 HNSLLRNSSSHLTSYNSGRPSSRTGRMNSRNQNLPKIPNSLSKISTTKLTELRVPKDSEI 752
Query: 736 -----NPYR-RSQTLQCQRNTRKPSI-----------------------VFDGLQESDGD 766
NP R + ++NT+ P+I ++ +++S +
Sbjct: 753 PSPAKNPNADRLRRFPVKKNTKTPAIKDPPRININSSDKSGSKNSPIKSLYQRMKQSKDN 812
Query: 767 SQSTN-------SHI--------EPSNVFQMGSESEDENDIDNGFYLS----------DN 801
S++ SH S+V GSES+ E + S +
Sbjct: 813 SKTFEVRRGNFFSHFNGDDDDSSSQSSVTSSGSESDSELSSTSSSCTSGTQSRNSSNNNA 872
Query: 802 HSDAESLPFEFGIDSEHGSVLSLRDL 827
+S+ ESLPFEFG+DSE GS + LRDL
Sbjct: 873 YSETESLPFEFGVDSEDGSGVLLRDL 898
>YGL179c [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kinase beta
and related serine/threonine protein kinases
Length = 560
Score = 301 bits (771), Expect = 4e-81
Identities = 179/487 (36%), Positives = 279/487 (56%), Gaps = 49/487 (10%)
Query: 93 VKETNTVSLEYDPISKRKVLNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKR 152
+KET V L Y+P++KR++LN +EI+ LG+GQ+GKVKLARDL T LVAIKI+NR +KR
Sbjct: 28 IKETRKVKLLYNPLTKRQILNNFEILATLGNGQYGKVKLARDLGTGALVAIKILNRFEKR 87
Query: 153 TFNDKFSNRFKTPQSGIEDEKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCS 212
+ +S + K +E+ ++ +EI +MK+CHHE+VV+L E+L+D +S K+YLVLEYCS
Sbjct: 88 S---GYSLQLK-----VENPRVNQEIEVMKRCHHENVVELYEILNDPESTKVYLVLEYCS 139
Query: 213 KGEIKWCPGDVIETKARGPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSE 272
+G +KWCP + +E KA GP +L+FQ++R++ V+ GLEYLH QGI HRDIKP+NLL+S
Sbjct: 140 RGPVKWCPENKMEIKAVGPSILTFQQSRKVVLDVVSGLEYLHSQGITHRDIKPSNLLISS 199
Query: 273 DGIVKISDFGVXXXXXXXXXXXXXXXXXXAKT--AGTPAFFAPEICLVEDTIKKFDLDPN 330
+G VKISDFGV K+ GTPAFFAPE+C E
Sbjct: 200 NGTVKISDFGVAMSTATGSTNIQSSHEQLLKSRALGTPAFFAPELCSTE----------- 248
Query: 331 SKEPIISFPTDIWAMGITLHCLLFGMLPFISDYELELFDKIVNEPLVFEPYQKIEQCQVS 390
KE S DIW++G+T++CLLFG LPF ++ LELFD I+N+PL F Y+++ S
Sbjct: 249 -KEYSCSSAIDIWSLGVTIYCLLFGKLPFNANSGLELFDSIINKPLEFPSYEEMLNGATS 307
Query: 391 QVECKEEYEEAQXXXXXXXXXXXXXRMAIQDAKKHPWVCWDFNHNDYMSDQEKSLKLIEQ 450
+ EEY +A+ R+ + D K HP++C + + + L
Sbjct: 308 GI-TMEEYTDAKDLLKKLLQKDPDKRIKLADIKVHPFMC-------HYGKSDAASVLTNL 359
Query: 451 SNFHR---SPSEQVEQICISEHEVDTAVGGIG---------HKIKNAVGKFLPSTKSNDE 498
FH SP +++ + V+++ + + ++ + + S +
Sbjct: 360 ETFHELKVSPPSSCKRVELVSLPVNSSFASLDSVYMENFDHNNLRTGADRNSTYSPSIYD 419
Query: 499 SNTNSVNEFNDSGNNKYIDGCLNSCASYTDNGNLILSEETYISPKDSTGYGNEGTNLVED 558
+NT S + +++ G+ + +S +S+T + + + IS +D+ G++ + E
Sbjct: 420 ANTLSPSAYHNIGSR---ESSYSSFSSFTSS----TAFASQISIQDAPAIGDQQCLIGES 472
Query: 559 SSSVPVH 565
SS+ V+
Sbjct: 473 GSSLRVN 479
>SPCC297.03 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kinase beta
and related serine/threonine protein kinases
Length = 652
Score = 269 bits (687), Expect = 2e-71
Identities = 174/432 (40%), Positives = 230/432 (52%), Gaps = 62/432 (14%)
Query: 90 YGPVKETNTVSLEYDPISKRKVLNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRH 149
+G VKET + +D S RK +N YEII+ELG G HGKVKL RD VT++L+AIKI+ +
Sbjct: 110 WGEVKETKKIRKRFDRFSGRKYINHYEIIKELGRGMHGKVKLGRDTVTRELLAIKIIPKT 169
Query: 150 KKRTFNDKFSNRFKTPQSGIEDEKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLE 209
++R + + + EK++REIAI+KKC H +VV+L EV+DD S K+YLVLE
Sbjct: 170 ERRP-------KLGRANASSQKEKVRREIAILKKCVHPNVVRLREVIDDPSSTKVYLVLE 222
Query: 210 YCSKGEIKWCPGDVIETKARGPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLL 269
Y S GE+ W D P+LS R+ FR V+LGLEYLH+QGIIHRDIKPANLL
Sbjct: 223 YMSGGEVPWTDCD--------SPVLSISEARQYFRDVVLGLEYLHYQGIIHRDIKPANLL 274
Query: 270 LSEDGIVKISDFGVXXXXXXXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDP 329
L+ VKISDFGV AKT GTPAFFAPE+C DLD
Sbjct: 275 LNSSNCVKISDFGV--SYIANAGLNEDNDVELAKTVGTPAFFAPELCWT-------DLD- 324
Query: 330 NSKEPIISFPTDIWAMGITLHCLLFGMLPFISDYELELFDKIVNEPLVFEPYQKIEQCQV 389
P IS D+WA+G+TL CLLFG PF + E ELFDKIVNE L I
Sbjct: 325 -RPRPKISEAIDVWALGVTLFCLLFGRCPFNASMEYELFDKIVNERLNIPSTPDIG---- 379
Query: 390 SQVECKEEYEEAQXXXXXXXXXXXXXRMAIQDAKKHPWVCWDFNHNDYMSDQEKSLKLIE 449
EE + R+ + + K HPW D + D EK L+ +
Sbjct: 380 ---------EEGRDLLKRLLCKDPEQRITLVEVKLHPWTL------DGLKDPEKWLQNTD 424
Query: 450 QSNFHRSPSEQVEQICISEHEVDTAVGGIGHKIKNAVGKFL----PSTKSNDESNT---- 501
S V ++ +S EV +A+ +G +++ +GK P + D S++
Sbjct: 425 PST--------VSRVEVSTDEVASAISLVG-RLRRKLGKLFRFRRPKARVFDSSSSVPSD 475
Query: 502 NSVNEFNDSGNN 513
+S+ SGN+
Sbjct: 476 SSICRPESSGNS 487
>Hs14150045 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kinase beta
and related serine/threonine protein kinases
Length = 505
Score = 171 bits (432), Expect = 7e-42
Identities = 122/348 (35%), Positives = 174/348 (49%), Gaps = 54/348 (15%)
Query: 112 LNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNR-----FKTPQ 166
LN Y++ E+G G +G V+LA + + A+K++++ KK F R + Q
Sbjct: 125 LNQYKLQSEIGKGAYGVVRLAYNESEDRHYAMKVLSK-KKLLKQYGFPRRPPPRGSQAAQ 183
Query: 167 SG-----IEDEKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPG 221
G + E++ +EIAI+KK H +VVKLIEVLDD +YLV + KG + P
Sbjct: 184 GGPAKQLLPLERVYQEIAILKKLDHVNVVKLIEVLDDPAEDNLYLVFDLLRKGPVMEVPC 243
Query: 222 DVIETKARGPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDF 281
D S ++ R R V+LGLEYLH Q I+HRDIKP+NLLL +DG VKI+DF
Sbjct: 244 D---------KPFSEEQARLYLRDVILGLEYLHCQKIVHRDIKPSNLLLGDDGHVKIADF 294
Query: 282 GVXXXXXXXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTD 341
GV + TAGTPAF APE + D+ + F D
Sbjct: 295 GV-------SNQFEGNDAQLSSTAGTPAFMAPE--AISDSGQSFS----------GKALD 335
Query: 342 IWAMGITLHCLLFGMLPFISDYELELFDKIVNEPLVFEPYQKIEQCQVSQVECKEEYEEA 401
+WA G+TL+C ++G PFI D+ L L KI NEP+VF E+ ++S EE
Sbjct: 336 VWATGVTLYCFVYGKCPFIDDFILALHRKIKNEPVVFP-----EEPEIS--------EEL 382
Query: 402 QXXXXXXXXXXXXXRMAIQDAKKHPWVCWDFNHNDYMSDQEKSLKLIE 449
+ R+ + D K HPWV N + + +E+ ++E
Sbjct: 383 KDLILKMLDKNPETRIGVPDIKLHPWV--TKNGEEPLPSEEEHCSVVE 428
>CE01146 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kinase beta
and related serine/threonine protein kinases
Length = 357
Score = 163 bits (412), Expect = 1e-39
Identities = 113/330 (34%), Positives = 156/330 (47%), Gaps = 52/330 (15%)
Query: 112 LNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIED 171
LN Y ++EE+G G +G VKLA + K L A+K+++ K + + R P+ E+
Sbjct: 18 LNQYRLMEEIGQGSYGIVKLAYNEEDKNLYALKVLD--KMKLLKNFACFRQPPPRRNKEN 75
Query: 172 ----------EKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPG 221
+ +++EIAI+KK H +VVKL+EVLDD +Y+V E+ KG I P
Sbjct: 76 AAPSVLRNPLQLVQKEIAILKKLSHPNVVKLVEVLDDPNDNYLYMVFEFVEKGSILEIPT 135
Query: 222 DVIETKARGPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDF 281
D L FR L GLEYLH+Q I+HRDIKP+NLLLS+ G VKI+DF
Sbjct: 136 D---------KPLDEDTAWSYFRDTLCGLEYLHYQKIVHRDIKPSNLLLSDIGQVKIADF 186
Query: 282 GVXXXXXXXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTD 341
GV + TAGTPAF APE L + D
Sbjct: 187 GV-------SCEFEGIDAFLSGTAGTPAFMAPEA-----------LTEGANHFYSGRAQD 228
Query: 342 IWAMGITLHCLLFGMLPFISDYELELFDKIVNEPLVFEPYQKIEQCQVSQVECKEEYEEA 401
IW++GITL+ + G +PF+ +Y + L KI N+P+VF E E
Sbjct: 229 IWSLGITLYAFVIGTVPFVDNYIIALHKKIKNDPIVFP-------------EAPILSEAL 275
Query: 402 QXXXXXXXXXXXXXRMAIQDAKKHPWVCWD 431
Q R+ + + K H WV D
Sbjct: 276 QDIILGMLKKDPGHRLMLHEVKVHTWVTRD 305
>Hs17933758 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kinase beta
and related serine/threonine protein kinases
Length = 588
Score = 156 bits (394), Expect = 2e-37
Identities = 116/354 (32%), Positives = 172/354 (47%), Gaps = 52/354 (14%)
Query: 84 SGQRITYGPVKETNTVSLEYDPISKRKVLNTYEIIEELGHGQHGKVKLARDLVTKQLVAI 143
S R+ P E++ VS+ + LN Y + +E+G G +G VKLA + A+
Sbjct: 136 SSPRLPRRPTVESHHVSIT--GMQDCVQLNQYTLKDEIGKGSYGVVKLAYNENDNTYYAM 193
Query: 144 KIVNRHK---KRTFNDKFSNRFKTPQSG--IED----EKIKREIAIMKKCHHEHVVKLIE 194
K++++ K + F + R P G I+ E++ +EIAI+KK H +VVKL+E
Sbjct: 194 KVLSKKKLIRQAGFPRRPPPRGTRPAPGGCIQPRGPIEQVYQEIAILKKLDHPNVVKLVE 253
Query: 195 VLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKARGPPLLSFQRTREIFRGVLLGLEYLH 254
VLDD +Y+V E ++G V+E P LS + R F+ ++ G+EYLH
Sbjct: 254 VLDDPNEDHLYMVFELVNQGP-------VMEVPTLKP--LSEDQARFYFQDLIKGIEYLH 304
Query: 255 FQGIIHRDIKPANLLLSEDGIVKISDFGVXXXXXXXXXXXXXXXXXXAKTAGTPAFFAPE 314
+Q IIHRDIKP+NLL+ EDG +KI+DFGV + T GTPAF APE
Sbjct: 305 YQKIIHRDIKPSNLLVGEDGHIKIADFGV-------SNEFKGSDALLSNTVGTPAFMAPE 357
Query: 315 ICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGITLHCLLFGMLPFISDYELELFDKIVNE 374
+ +T K F D+WAMG+TL+C +FG PF+ + + L KI ++
Sbjct: 358 --SLSETRKIFS----------GKALDVWAMGVTLYCFVFGQCPFMDERIMCLHSKIKSQ 405
Query: 375 PLVFEPYQKIEQCQVSQVECKEEYEEAQXXXXXXXXXXXXXRMAIQDAKKHPWV 428
L F I E+ + R+ + + K HPWV
Sbjct: 406 ALEFPDQPDIA-------------EDLKDLITRMLDKNPESRIVVPEIKLHPWV 446
>At5g60550 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kinase beta
and related serine/threonine protein kinases
Length = 407
Score = 153 bits (386), Expect = 2e-36
Identities = 110/379 (29%), Positives = 170/379 (44%), Gaps = 57/379 (15%)
Query: 58 EKQRQRQLNHPLHQNHIRTVLGSHLNSGQRITYGPVKETNTVSLEYDPISKRKVLNTYEI 117
E++ + ++ +L L++G + PV+ETN + D + K +N Y
Sbjct: 53 EEEDEEEVEQKSRSKRSEEILKYRLDNGLICRHIPVRETNELIRGEDE-NGDKTINEYVR 111
Query: 118 IEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIEDEKIKRE 177
+ ++G G +GKV L R + Q AIK F+ R + S + RE
Sbjct: 112 VCKIGSGSYGKVVLYRSTLDGQYYAIK--------AFHKSHLLRLRVAPSETAMSDVLRE 163
Query: 178 IAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKARGPP-LLSF 236
+ IMK H ++V LIEV+DD ++ Y+VLEY KW GPP L
Sbjct: 164 VMIMKILEHPNIVNLIEVIDDPETDHFYMVLEYVDG---KWV------YDGSGPPGALGE 214
Query: 237 QRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXXXXXXXXXXXXX 296
+ R+ R ++ GL YLH +IH DIKP NLL++ G VKI DF V
Sbjct: 215 KTARKYLRDIVTGLMYLHAHDVIHGDIKPDNLLVTSSGTVKIGDFSV-------SQVFKD 267
Query: 297 XXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGITLHCLLFGM 356
++ GTP F APE CL + D WA+G+TL+C++ G
Sbjct: 268 DDDQLRRSPGTPVFTAPECCLGITYSGR--------------AADTWAVGVTLYCMILGQ 313
Query: 357 LPFISDYELELFDKIVNEPLVF-EPYQKIEQCQVSQVECKEEYEEAQXXXXXXXXXXXXX 415
PF++D + +DKIVN PL+ + + + + + CK+ +
Sbjct: 314 YPFLADTLQDTYDKIVNNPLIIPDGLNPLLRDLIEGLLCKDPSQ---------------- 357
Query: 416 RMAIQDAKKHPWVCWDFNH 434
RM +++ +HPWV + H
Sbjct: 358 RMTLKNVSEHPWVIGEDGH 376
>At3g45240 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kinase beta
and related serine/threonine protein kinases
Length = 382
Score = 145 bits (366), Expect = 3e-34
Identities = 115/400 (28%), Positives = 169/400 (41%), Gaps = 71/400 (17%)
Query: 58 EKQRQRQLNHPLHQNHIRTVLGSHLNSGQRITYGPVKETNTVSLEYDPISKRKVLNTYEI 117
E + + ++ +L L +G PVKETN ++ D K +N +
Sbjct: 41 EGEEEEEVEELSRSKRSEEILKCKLQNGLVCRQFPVKETNKLTRGEDE-DGNKTINEFVR 99
Query: 118 IEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIEDEKIKRE 177
++G G +GKV L R V + AIK F+ +R + S + RE
Sbjct: 100 ERKIGSGSYGKVVLYRSTVDDKHYAIK--------AFHKSHLSRLRVAPSETAMGDVLRE 151
Query: 178 IAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKARGPP-LLSF 236
+ IMK H ++V LIEV+DD + Y+VLEY KW D GPP L
Sbjct: 152 VMIMKTLEHPNIVNLIEVIDDPEFDDFYMVLEYVDG---KWAYDD------SGPPGALGE 202
Query: 237 QRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXXXXXXXXXXXXX 296
R+ R V+ GL YLH +IH DIKP NLL++ G VKI DF V
Sbjct: 203 ITARKYLRDVVAGLMYLHAHNVIHGDIKPDNLLVTSTGRVKIGDFSV----------SQD 252
Query: 297 XXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGITLHCLLFGM 356
++ GTP F APE CL + + + D WA+G+TL+C++ G
Sbjct: 253 DDDQLRRSPGTPVFTAPECCL--------GITYSGRS------ADTWAVGVTLYCMILGQ 298
Query: 357 LPFISDYELELFDKIVNEPLVF-EPYQKIEQCQVSQVECKEEYEEAQXXXXXXXXXXXXX 415
PF+ D + +DKIV+ PL+ E + + + CK+ +
Sbjct: 299 YPFLGDTLQDTYDKIVHNPLIIPEGLNPRLRDLIEGLLCKDPNQ---------------- 342
Query: 416 RMAIQDAKKHPWV-----------CWDFNHNDYMSDQEKS 444
RM ++ +HPW+ CW + DQ S
Sbjct: 343 RMTLKAVAEHPWITGEDGAISEYCCWCKRKAEEEEDQNHS 382
>7289880 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kinase beta
and related serine/threonine protein kinases
Length = 338
Score = 138 bits (348), Expect = 4e-32
Identities = 105/305 (34%), Positives = 147/305 (47%), Gaps = 49/305 (16%)
Query: 172 EKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKARGP 231
+++ REIA++KK H +VVKL+EVLDD +Y+V E +GE+ P D P
Sbjct: 28 DRVYREIAVLKKLDHPNVVKLVEVLDDPLEDSLYMVFELVKQGEVLRIPTD-------NP 80
Query: 232 PLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXXXXXXXX 291
LS +R IFR LLGLEYLH Q IIH DIKP NLLL+E G VKI+D GV
Sbjct: 81 --LSEKRAWSIFRESLLGLEYLHHQKIIHADIKPGNLLLTEFGHVKIADLGV-----CNE 133
Query: 292 XXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGITLHC 351
TAGTPAF APE L P E D+WA+G TL+
Sbjct: 134 FLGDDATISNGSTAGTPAFRAPE-----------TLIPGQNE-YCGRAADVWALGATLYS 181
Query: 352 LLFGMLPFISDYELELFDKIVNEPLVFEPYQKIEQCQVSQVECKEEYEEAQXXXXXXXXX 411
L+FG +PF++D L++KI + + F K+ + S + E Q
Sbjct: 182 LIFGNVPFLADSVPLLYEKIKQDSVKFPENHKVTENLKSCIVQMLEKNPTQ--------- 232
Query: 412 XXXXRMAIQDAKKHPWVCWDFNHNDY-MSDQEKSLKLIEQSNFHRSPSEQVEQICISEHE 470
R+ I K WV D DY + +E++ L++ + E ++ + S +
Sbjct: 233 ----RITIPQLKTSKWVTSD---GDYPLPTEEENCCLVQVDD------EDIDSVVRSIPK 279
Query: 471 VDTAV 475
+DT +
Sbjct: 280 LDTLI 284
>YKL048c [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kinase beta
and related serine/threonine protein kinases
Length = 640
Score = 134 bits (338), Expect = 6e-31
Identities = 104/333 (31%), Positives = 157/333 (46%), Gaps = 48/333 (14%)
Query: 84 SGQRITYGPV--KETNTVSLEYDPISKR--------KVLNTYEIIEELGHGQHGKVKLAR 133
S Q+ TY + + +T+ E P K+ K +N Y + G GQ G V+ A
Sbjct: 47 SQQKPTYSTIIGENIHTILDEIRPYVKKITVSDQDKKTINQYTLGVSAGSGQFGYVRKAY 106
Query: 134 DLVTKQLVAIKI------------VNRHKKRTFNDKFSNRFKTPQSGIED------EKIK 175
++VA+KI VN+ ++ K + T SG E EK +
Sbjct: 107 SSTLGKVVAVKIIPKKPWNAQQYSVNQVMRQIQLWKSKGKITTNMSGNEAMRLMNIEKCR 166
Query: 176 REI-AIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKARGPPLL 234
EI A + ++ H+V+LIE LD S I++V +CS GE++W D + + ++
Sbjct: 167 WEIFAASRLRNNVHIVRLIECLDSPFSESIWIVTNWCSLGELQWKRDDDEDILPQWKKIV 226
Query: 235 SFQRT-----REIFRGVLLGLEYLHFQGIIHRDIKPANLLL-SEDGIVKISDFG-----V 283
+ ++I + GLEYLH QG IHRDIKP+N+LL E+ + K+SDFG
Sbjct: 227 ISNCSVSTFAKKILEDMTKGLEYLHSQGCIHRDIKPSNILLDEEEKVAKLSDFGSCIFTP 286
Query: 284 XXXXXXXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIW 343
K GTPAF APE+C + ++ + F D F DIW
Sbjct: 287 QSLPFSDANFEDCFQRELNKIVGTPAFIAPELCHLGNSKRDFVTD--------GFKLDIW 338
Query: 344 AMGITLHCLLFGMLPFISDYELELFDKIVNEPL 376
++G+TL+CLL+ LPF + E E + KI+ L
Sbjct: 339 SLGVTLYCLLYNELPFFGENEFETYHKIIEVSL 371
>Hs7661974 [T] KOG0583 Serine/threonine protein kinase
Length = 651
Score = 127 bits (320), Expect = 7e-29
Identities = 102/364 (28%), Positives = 167/364 (45%), Gaps = 74/364 (20%)
Query: 110 KVLNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGI 169
++L YE+ E +G G KVKLA ++T ++VAIKI++++ G
Sbjct: 6 ELLKYYELHETIGTGGFAKVKLACHILTGEMVAIKIMDKNTL----------------GS 49
Query: 170 EDEKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKAR 229
+ +IK EI +K H+H+ +L VL+ A KI++VLEYC GE+ D I ++ R
Sbjct: 50 DLPRIKTEIEALKNLRHQHICQLYHVLETAN--KIFMVLEYCPGGELF----DYIISQDR 103
Query: 230 GPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXXXXXX 289
LS + TR +FR ++ + Y+H QG HRD+KP NLL E +K+ DFG+
Sbjct: 104 ----LSEEETRVVFRQIVSAVAYVHSQGYAHRDLKPENLLFDEYHKLKLIDFGLCAKPKG 159
Query: 290 XXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGITL 349
G+ A+ APE+ + + D+W+MGI L
Sbjct: 160 NKDYHLQT------CCGSLAYAAPELI--------------QGKSYLGSEADVWSMGILL 199
Query: 350 HCLLFGMLPFISDYELELFDKIV----NEPLVFEPYQKIEQCQVSQVECKEEYEEAQXXX 405
+ L+ G LPF D + L+ KI+ + P P + Q+ QV+ K+
Sbjct: 200 YVLMCGFLPFDDDNVMALYKKIMRGKYDVPKWLSPSSILLLQQMLQVDPKK--------- 250
Query: 406 XXXXXXXXXXRMAIQDAKKHPWVCWDFNHNDYMSDQEKSLKL-----IEQSNFHRSPSEQ 460
R+++++ HPW+ D+N+ + + L E S HR+ +
Sbjct: 251 ----------RISMKNLLNHPWIMQDYNYPVEWQSKNPFIHLDDDCVTELSVHHRNNRQT 300
Query: 461 VEQI 464
+E +
Sbjct: 301 MEDL 304
>Hs4507271 [T] KOG0583 Serine/threonine protein kinase
Length = 433
Score = 126 bits (316), Expect = 2e-28
Identities = 88/280 (31%), Positives = 139/280 (49%), Gaps = 39/280 (13%)
Query: 93 VKETNTVSLEYDPISKR-KVLNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKK 151
+ ++ + Y P KR K++ Y + + LG G +GKVK D T A+KI+ + K
Sbjct: 26 IHRIDSTEVIYQPRRKRAKLIGKYLMGDLLGEGSYGKVKEVLDSETLCRRAVKILKKKKL 85
Query: 152 RTFNDKFSNRFKTPQSGIEDEKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYC 211
R + +N +K+EI ++++ H++V++L++VL + + +K+Y+V+EYC
Sbjct: 86 RRIPNGEAN-------------VKKEIQLLRRLRHKNVIQLVDVLYNEEKQKMYMVMEYC 132
Query: 212 SKGEIKWCPGDVIETKARGPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLS 271
G + D + K R P + F ++ GLEYLH QGI+H+DIKP NLLL+
Sbjct: 133 VCGMQEML--DSVPEK-RFPVC----QAHGYFCQLIDGLEYLHSQGIVHKDIKPGNLLLT 185
Query: 272 EDGIVKISDFGVXXXXXXXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNS 331
G +KISD GV + G+PAF PEI N
Sbjct: 186 TGGTLKISDLGVAEALHPFAADDTCRT-----SQGSPAFQPPEIA-------------NG 227
Query: 332 KEPIISFPTDIWAMGITLHCLLFGMLPFISDYELELFDKI 371
+ F DIW+ G+TL+ + G+ PF D +LF+ I
Sbjct: 228 LDTFSGFKVDIWSAGVTLYNITTGLYPFEGDNIYKLFENI 267
>7299793 [T] KOG0583 Serine/threonine protein kinase
Length = 540
Score = 123 bits (309), Expect = 1e-27
Identities = 88/263 (33%), Positives = 130/263 (48%), Gaps = 40/263 (15%)
Query: 110 KVLNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGI 169
K++ Y + + LG G +GKVK A + +A+KI+ + K R + P
Sbjct: 140 KMVGKYIMGDVLGEGSYGKVKEAMNSENLCRLAVKILTKRKLR----------RIPNG-- 187
Query: 170 EDEKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKA- 228
++ + REIA++K+ H HVV+L++VL + + +K+YLV+EYC G ++I+ +
Sbjct: 188 -EQNVTREIALLKQLKHRHVVELVDVLYNEEKQKMYLVMEYCVGGL-----QEMIDYQPD 241
Query: 229 RGPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXXXXX 288
+ PL + F+ ++ GLEYLH +IH+DIKP NLLLS D +KISDFGV
Sbjct: 242 KRMPLF---QAHGYFKQLVDGLEYLHSCRVIHKDIKPGNLLLSLDQTLKISDFGVAEQLD 298
Query: 289 XXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGIT 348
G+PAF PEI N E F DIW+ G+T
Sbjct: 299 LFAPDDTCTTG-----QGSPAFQPPEIA-------------NGHETFAGFKVDIWSSGVT 340
Query: 349 LHCLLFGMLPFISDYELELFDKI 371
L+ L G PF D L + I
Sbjct: 341 LYNLATGQYPFEGDNIYRLLENI 363
>At5g45820 [T] KOG0583 Serine/threonine protein kinase
Length = 439
Score = 121 bits (304), Expect = 5e-27
Identities = 84/261 (32%), Positives = 128/261 (48%), Gaps = 44/261 (16%)
Query: 111 VLNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIE 170
++ YE+ LG G KV AR++ T + VAIK++++ K + G+
Sbjct: 8 LMRKYELGRLLGQGTFAKVYHARNIKTGESVAIKVIDKQK-------------VAKVGLI 54
Query: 171 DEKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKARG 230
D+ IKREI++M+ H HVV L EV+ A KIY +EY GE+ + ++G
Sbjct: 55 DQ-IKREISVMRLVRHPHVVFLHEVM--ASKTKIYFAMEYVKGGEL-------FDKVSKG 104
Query: 231 PPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXXXXXXX 290
L R+ F+ ++ ++Y H +G+ HRD+KP NLLL E+G +KISDFG+
Sbjct: 105 K--LKENIARKYFQQLIGAIDYCHSRGVYHRDLKPENLLLDENGDLKISDFGLSALRESK 162
Query: 291 XXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGITLH 350
T GTPA+ APE+ K+ D+W+ G+ L+
Sbjct: 163 QQDGLLHT-----TCGTPAYVAPEVI--------------GKKGYDGAKADVWSCGVVLY 203
Query: 351 CLLFGMLPFISDYELELFDKI 371
LL G LPF +E++ KI
Sbjct: 204 VLLAGFLPFHEQNLVEMYRKI 224
>At2g34180 [T] KOG0583 Serine/threonine protein kinase
Length = 502
Score = 121 bits (303), Expect = 7e-27
Identities = 102/359 (28%), Positives = 159/359 (43%), Gaps = 63/359 (17%)
Query: 88 ITYGPVKETNTVSLEYDPISKRK--VLNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKI 145
+T KET+T P + + +++ YEI + LGHG KV LAR++ + + VAIK+
Sbjct: 28 VTKNTNKETSTPESPRSPRTPQGSILMDKYEIGKLLGHGSFAKVYLARNIHSGEDVAIKV 87
Query: 146 VNRHKKRTFNDKFSNRFKTPQSGIEDEKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIY 205
+++ K +SG+ IKREI+I+++ H ++V L+EV+ A KIY
Sbjct: 88 IDKEK-------------IVKSGLAGH-IKREISILRRVRHPYIVHLLEVM--ATKTKIY 131
Query: 206 LVLEYCSKGEIKWCPGDVIETKARGPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKP 265
+V+EY GE+ T ARG L R F+ ++ + + H +G+ HRD+K
Sbjct: 132 IVMEYVRGGEL-------YNTVARGR--LREGTARRYFQQLISSVAFCHSRGVYHRDLKL 182
Query: 266 ANLLLSEDGIVKISDFGVXXXXXXXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKF 325
NLLL + G VK+SDFG+ GTPA+ APE+ T K +
Sbjct: 183 ENLLLDDKGNVKVSDFGLSVVSEQLKQEGICQTF-----CGTPAYLAPEVL----TRKGY 233
Query: 326 DLDPNSKEPIISFPTDIWAMGITLHCLLFGMLPFISDYELELFDKIVNEPLVFEPYQKIE 385
+ DIW+ G+ L L+ G LPF L ++ KI
Sbjct: 234 E----------GAKADIWSCGVILFVLMAGYLPFDDKNILVMYTKIYK------------ 271
Query: 386 QCQVSQVECKEEYE-EAQXXXXXXXXXXXXXRMAIQDAKKHPWVCWDFNHNDYMSDQEK 443
Q +C + + E R+ I + KH W F H + + +K
Sbjct: 272 ----GQFKCPKWFSPELARLVTRMLDTNPDTRITIPEIMKHRWFKKGFKHVKFYIENDK 326
>CE28218 [D] KOG0588 Serine/threonine protein kinase
Length = 914
Score = 120 bits (302), Expect = 8e-27
Identities = 101/355 (28%), Positives = 154/355 (42%), Gaps = 67/355 (18%)
Query: 105 PISKRKVLNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKT 164
P+++ + Y++ + LG GQ G VK +T + VAIKIVN+ K
Sbjct: 37 PVAQAQYCGPYKLEKTLGKGQTGLVKTGTHCITGRKVAIKIVNKEKL------------- 83
Query: 165 PQSGIEDEKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVI 224
S +K++REIAIMK H HV+ L +V ++ K +YL+LE+ S GE+ D +
Sbjct: 84 --SESVLQKVEREIAIMKLIEHPHVLHLYDVYENKKY--LYLLLEHVSGGELF----DYL 135
Query: 225 ETKARGPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVX 284
K R L + R+ FR ++ L++ H I HRD+KP NLLL E +K++DFG+
Sbjct: 136 VRKGR----LMSKEARKFFRQIISALDFCHAHNICHRDLKPENLLLDERNNIKVADFGMA 191
Query: 285 XXXXXXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWA 344
+ G+P + PE+ E K+D D+W+
Sbjct: 192 SLQVEGSMLET--------SCGSPHYACPEVIRGE----KYD----------GRKADVWS 229
Query: 345 MGITLHCLLFGMLPFISDYELELFDKIVNEPLVFEPYQKIEQCQVSQVECKEEYEEAQXX 404
G+ L+ LL G LPF D L +K+ VF + S + E + +
Sbjct: 230 CGVILYALLVGALPFDDDNLRNLLEKVKRG--VFHIPHFVPADVQSLLRAMIEVDPGK-- 285
Query: 405 XXXXXXXXXXXRMAIQDAKKHPWVCWDFNHNDYMSDQEKSLKLIEQSNFHRSPSE 459
R ++ D KHPWV +D E L + + H P E
Sbjct: 286 -----------RYSLADVFKHPWV-----SGTTKADPELELPMSQVVQTHVIPGE 324
>At5g45810 [T] KOG0583 Serine/threonine protein kinase
Length = 483
Score = 120 bits (301), Expect = 1e-26
Identities = 82/261 (31%), Positives = 129/261 (49%), Gaps = 44/261 (16%)
Query: 111 VLNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIE 170
+L YE+ LGHG KV LAR+ + + VAIK++++ K +SG+
Sbjct: 24 ILGKYEMGRLLGHGTFAKVYLARNAQSGESVAIKVIDKEK-------------VLKSGLI 70
Query: 171 DEKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKARG 230
IKREI+I+++ H ++V+L EV+ A KIY V+EY GE+ A+G
Sbjct: 71 AH-IKREISILRRVRHPNIVQLFEVM--ATKSKIYFVMEYVKGGEL-------FNKVAKG 120
Query: 231 PPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXXXXXXX 290
L + R+ F+ ++ + + HF+G+ HRD+KP NLLL E+G +K+SDFG+
Sbjct: 121 R--LKEEMARKYFQQLISAVSFCHFRGVYHRDLKPENLLLDENGNLKVSDFGLSAVSDQI 178
Query: 291 XXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGITLH 350
GTPA+ APE+ +++ DIW+ G+ L
Sbjct: 179 RQDGLFHTF-----CGTPAYVAPEVL--------------ARKGYDGAKVDIWSCGVILF 219
Query: 351 CLLFGMLPFISDYELELFDKI 371
L+ G LPF + ++ KI
Sbjct: 220 VLMAGFLPFHDRNVMAMYKKI 240
>Hs20545245 [D] KOG0588 Serine/threonine protein kinase
Length = 795
Score = 119 bits (299), Expect = 2e-26
Identities = 99/313 (31%), Positives = 143/313 (45%), Gaps = 62/313 (19%)
Query: 115 YEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIEDEKI 174
Y + + LG GQ G VKL +T Q VAIKIVNR K S K+
Sbjct: 51 YRLEKTLGKGQTGLVKLGVHCITGQKVAIKIVNREKL---------------SESVLMKV 95
Query: 175 KREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKARGPPLL 234
+REIAI+K H HV+KL +V ++ K +YLVLE+ S GE+ D + K R P
Sbjct: 96 EREIAILKLIEHPHVLKLHDVYENKKY--LYLVLEHVSGGELF----DYLVKKGRLTP-- 147
Query: 235 SFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXXXXXXXXXXX 294
+ R+ FR ++ L++ H I HRD+KP NLLL E ++I+DFG+
Sbjct: 148 --KEARKFFRQIVSALDFCHSYSICHRDLKPENLLLDEKNNIRIADFGMASLQVGDSLLE 205
Query: 295 XXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGITLHCLLF 354
+ G+P + PE+ E K+D D+W+ G+ L LL
Sbjct: 206 T--------SCGSPHYACPEVIKGE----KYD----------GRRADMWSCGVILFALLV 243
Query: 355 GMLPFISDYELELFDKIVNEPLVFEPYQKIEQCQVSQVECKEEYEEAQXXXXXXXXXXXX 414
G LPF D +L +K V + P+ CQ S + E E +
Sbjct: 244 GALPFDDDNLRQLLEK-VKRGVFHMPHFIPPDCQ-SLLRGMIEVEPEK------------ 289
Query: 415 XRMAIQDAKKHPW 427
R++++ +KHPW
Sbjct: 290 -RLSLEQIQKHPW 301
>Hs7662170 [R] KOG0611 Predicted serine/threonine protein kinase
Length = 661
Score = 119 bits (297), Expect = 3e-26
Identities = 94/359 (26%), Positives = 150/359 (41%), Gaps = 66/359 (18%)
Query: 108 KRKVLNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQS 167
K + + YE+ E LG G +GKVK A + + ++VAIK + + K + D
Sbjct: 48 KHNLKHRYELQETLGKGTYGKVKRATERFSGRVVAIKSIRKDKIKDEQDMVH-------- 99
Query: 168 GIEDEKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETK 227
I+REI IM +H H++ + EV ++ KI +++EY SKGE+ D I +
Sbjct: 100 ------IRREIEIMSSLNHPHIISIYEVFENKD--KIVIIMEYASKGELY----DYISER 147
Query: 228 ARGPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXXXX 287
R LS + TR FR ++ + Y H G++HRD+K N+LL ++ +KI+DFG+
Sbjct: 148 RR----LSERETRHFFRQIVSAVHYCHKNGVVHRDLKLENILLDDNCNIKIADFGLSNLY 203
Query: 288 XXXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGI 347
G+P + +PEI + P D WA+G+
Sbjct: 204 QKDKFLQTF--------CGSPLYASPEIV--------------NGRPYRGPEVDSWALGV 241
Query: 348 TLHCLLFGMLPFISDYELELFDKIVNEPLVFEPYQKIEQCQVSQVECKEEYEEAQXXXXX 407
L+ L++G +PF F+ I Q + + +A+
Sbjct: 242 LLYTLVYGTMPFDG----------------FDHKNLIRQISSGEYREPTQPSDARGLIRW 285
Query: 408 XXXXXXXXRMAIQDAKKHPWVCWDFNHN----DYMSDQEKSLKLIEQSNFHRSPSEQVE 462
R I+D H WV W + + D + D E L HRS Q +
Sbjct: 286 MLMVNPDRRATIEDIANHWWVNWGYKSSVCDCDALHDSESPLLARIIDWHHRSTGLQAD 344
>At4g18700 [T] KOG0583 Serine/threonine protein kinase
Length = 489
Score = 119 bits (297), Expect = 3e-26
Identities = 92/363 (25%), Positives = 152/363 (41%), Gaps = 61/363 (16%)
Query: 111 VLNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIE 170
+L YE+ + LGHG KV LAR++ T + VAIK++++ K G
Sbjct: 22 ILGRYEMGKLLGHGTFAKVYLARNVKTNESVAIKVIDKEKVL--------------KGGL 67
Query: 171 DEKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKARG 230
IKREI+I+++ H ++V+L EV+ A KIY V+EY GE+ A+G
Sbjct: 68 IAHIKREISILRRVRHPNIVQLFEVM--ATKAKIYFVMEYVRGGEL-------FNKVAKG 118
Query: 231 PPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXXXXXXX 290
L + R+ F+ ++ + + H +G+ HRD+KP NLLL E+G +K+SDFG+
Sbjct: 119 R--LKEEVARKYFQQLISAVTFCHARGVYHRDLKPENLLLDENGNLKVSDFGLSAVSDQI 176
Query: 291 XXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGITLH 350
GTPA+ APE+ +++ + DIW+ G+ L
Sbjct: 177 RQDGLFHTF-----CGTPAYVAPEVL--------------ARKGYDAAKVDIWSCGVILF 217
Query: 351 CLLFGMLPFISDYELELFDKIVNEPLVFEPYQKIEQCQVSQVECKEEYE-EAQXXXXXXX 409
L+ G LPF + ++ KI + C + E
Sbjct: 218 VLMAGYLPFHDRNVMAMYKKIYR----------------GEFRCPRWFSTELTRLLSKLL 261
Query: 410 XXXXXXRMAIQDAKKHPWVCWDFNHNDYMSDQEKSLKLIEQSNFHRSPSEQVEQICISEH 469
R + ++ W F H + + +K +++ E SE
Sbjct: 262 ETNPEKRFTFPEIMENSWFKKGFKHIKFYVEDDKLCNVVDDDELESDSVESDRDSAASES 321
Query: 470 EVD 472
E++
Sbjct: 322 EIE 324
>At3g01090 [T] KOG0583 Serine/threonine protein kinase
Length = 512
Score = 119 bits (297), Expect = 3e-26
Identities = 83/261 (31%), Positives = 123/261 (46%), Gaps = 46/261 (17%)
Query: 111 VLNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIE 170
+L Y++ LG G G+VK+A +T VAIKI+NR K +
Sbjct: 15 ILPNYKLGRTLGIGSFGRVKIAEHALTGHKVAIKILNRRKIKNME--------------M 60
Query: 171 DEKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKARG 230
+EK++REI I++ H H+++L EV++ IYLV+EY + GE+ D I K R
Sbjct: 61 EEKVRREIKILRLFMHPHIIRLYEVIETPTD--IYLVMEYVNSGELF----DYIVEKGR- 113
Query: 231 PPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXXXXXXX 290
L R F+ ++ G+EY H ++HRD+KP NLLL VKI+DFG+
Sbjct: 114 ---LQEDEARNFFQQIISGVEYCHRNMVVHRDLKPENLLLDSKCNVKIADFGLSNIMRDG 170
Query: 291 XXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGITLH 350
+ G+P + APE+ S + D+W+ G+ L+
Sbjct: 171 HFLKT--------SCGSPNYAAPEVI--------------SGKLYAGPEVDVWSCGVILY 208
Query: 351 CLLFGMLPFISDYELELFDKI 371
LL G LPF + LF KI
Sbjct: 209 ALLCGTLPFDDENIPNLFKKI 229
>At1g29230 [T] KOG0583 Serine/threonine protein kinase
Length = 520
Score = 119 bits (297), Expect = 3e-26
Identities = 97/370 (26%), Positives = 158/370 (42%), Gaps = 61/370 (16%)
Query: 111 VLNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIE 170
++ YE+ + LGHG KV LA+++ + VAIK++++ K +SG+
Sbjct: 70 LMGKYELGKLLGHGTFAKVYLAQNIKSGDKVAIKVIDKEK-------------IMKSGLV 116
Query: 171 DEKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKARG 230
IKREI+I+++ H ++V L EV+ A KIY V+EY GE+ T A+G
Sbjct: 117 AH-IKREISILRRVRHPYIVHLFEVM--ATKSKIYFVMEYVGGGEL-------FNTVAKG 166
Query: 231 PPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXXXXXXX 290
L + R F+ ++ + + H +G+ HRD+KP NLLL G +K+SDFG+
Sbjct: 167 R--LPEETARRYFQQLISSVSFCHGRGVYHRDLKPENLLLDNKGNLKVSDFGLSAVAEQL 224
Query: 291 XXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGITLH 350
GTPA+ APE+ T K +D + D+W+ G+ L
Sbjct: 225 RQDGLCHTF-----CGTPAYIAPEVL----TRKGYD----------AAKADVWSCGVILF 265
Query: 351 CLLFGMLPFISDYELELFDKIVNEPLVFEPYQKIEQCQVSQVECKEEY-EEAQXXXXXXX 409
L+ G +PF + ++ KI + C + +
Sbjct: 266 VLMAGHIPFYDKNIMVMYKKIYK----------------GEFRCPRWFSSDLVRLLTRLL 309
Query: 410 XXXXXXRMAIQDAKKHPWVCWDFNHNDYMSDQEKSLKLIEQSNFHRSPSEQVEQICISEH 469
R+ I + K+ W F H + + +K + E S S + + S+
Sbjct: 310 DTNPDTRITIPEIMKNRWFKKGFKHVKFYIEDDKLCREDEDEEEEASSSGRSSTVSESDA 369
Query: 470 EVDTAVGGIG 479
E D GIG
Sbjct: 370 EFDVKRMGIG 379
>At5g10930 [T] KOG0583 Serine/threonine protein kinase
Length = 445
Score = 118 bits (296), Expect = 4e-26
Identities = 87/276 (31%), Positives = 132/276 (47%), Gaps = 47/276 (17%)
Query: 108 KRKVLNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQS 167
+R + YE+ LG G KV ++++ + VAIK++N+ + K P
Sbjct: 5 RRVLFGKYEMGRLLGKGTFAKVYYGKEIIGGECVAIKVINKDQV----------MKRPGM 54
Query: 168 GIEDEKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEI--KWCPGDVIE 225
E+IKREI+IMK H ++V+L EV+ A KI+ V+E+ GE+ K G + E
Sbjct: 55 M---EQIKREISIMKLVRHPNIVELKEVM--ATKTKIFFVMEFVKGGELFCKISKGKLHE 109
Query: 226 TKARGPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXX 285
AR F+ ++ ++Y H +G+ HRD+KP NLLL E+G +KISDFG+
Sbjct: 110 DAAR-----------RYFQQLISAVDYCHSRGVSHRDLKPENLLLDENGDLKISDFGLSA 158
Query: 286 XXXXXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAM 345
GTPA+ APE+ +KK D DIW+
Sbjct: 159 LPEQILQDGLLHT-----QCGTPAYVAPEV------LKKKGYD--------GAKADIWSC 199
Query: 346 GITLHCLLFGMLPFISDYELELFDKIVNEPLVFEPY 381
G+ L+ LL G LPF + + ++ KI F P+
Sbjct: 200 GVVLYVLLAGCLPFQDENLMNMYRKIFRADFEFPPW 235
>At3g29160 [T] KOG0583 Serine/threonine protein kinase
Length = 512
Score = 118 bits (296), Expect = 4e-26
Identities = 82/261 (31%), Positives = 123/261 (46%), Gaps = 46/261 (17%)
Query: 111 VLNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIE 170
+L Y++ + LG G GKVK+A +VT VAIKI+NR K +
Sbjct: 16 ILPNYKLGKTLGIGSFGKVKIAEHVVTGHKVAIKILNRRKIKNME--------------M 61
Query: 171 DEKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKARG 230
+EK++REI I++ H H+++ EV++ IY+V+EY GE+ D I K R
Sbjct: 62 EEKVRREIKILRLFMHPHIIRQYEVIETTSD--IYVVMEYVKSGELF----DYIVEKGR- 114
Query: 231 PPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXXXXXXX 290
L R F+ ++ G+EY H ++HRD+KP NLLL +KI+DFG+
Sbjct: 115 ---LQEDEARNFFQQIISGVEYCHRNMVVHRDLKPENLLLDSRCNIKIADFGLSNVMRDG 171
Query: 291 XXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGITLH 350
+ G+P + APE+ S + D+W+ G+ L+
Sbjct: 172 HFLKT--------SCGSPNYAAPEVI--------------SGKLYAGPEVDVWSCGVILY 209
Query: 351 CLLFGMLPFISDYELELFDKI 371
LL G LPF + LF KI
Sbjct: 210 ALLCGTLPFDDENIPNLFKKI 230
>At1g01140 [T] KOG0583 Serine/threonine protein kinase
Length = 447
Score = 118 bits (296), Expect = 4e-26
Identities = 88/277 (31%), Positives = 132/277 (46%), Gaps = 44/277 (15%)
Query: 105 PISKRKVLNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKT 164
P S+ +V N YE+ LG G KVK A++ VT AIKI++R K F K
Sbjct: 10 PASRTRVGN-YEMGRTLGEGSFAKVKYAKNTVTGDQAAIKILDREK--VFRHKMV----- 61
Query: 165 PQSGIEDEKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVI 224
E++KREI+ MK H +VV++IEV+ A KIY+VLE + GE+ D I
Sbjct: 62 -------EQLKREISTMKLIKHPNVVEIIEVM--ASKTKIYIVLELVNGGELF----DKI 108
Query: 225 ETKARGPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVX 284
+ R L R F+ ++ ++Y H +G+ HRD+KP NL+L +G++K+SDFG+
Sbjct: 109 AQQGR----LKEDEARRYFQQLINAVDYCHSRGVYHRDLKPENLILDANGVLKVSDFGLS 164
Query: 285 XXXXXXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWA 344
GTP + APE+ + K +D D+W+
Sbjct: 165 AFSRQVREDGLLHT-----ACGTPNYVAPEVL----SDKGYD----------GAAADVWS 205
Query: 345 MGITLHCLLFGMLPFISDYELELFDKIVNEPLVFEPY 381
G+ L L+ G LPF + L+ +I P+
Sbjct: 206 CGVILFVLMAGYLPFDEPNLMTLYKRICKAEFSCPPW 242
>At5g39440 [T] KOG0583 Serine/threonine protein kinase
Length = 494
Score = 117 bits (294), Expect = 7e-26
Identities = 119/418 (28%), Positives = 182/418 (43%), Gaps = 81/418 (19%)
Query: 111 VLNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIE 170
+L Y I + LGHG KVKLA + T VAIKI+NR K + GIE
Sbjct: 15 ILPNYRIGKTLGHGSFAKVKLALHVATGHKVAIKILNRSKIKNM-------------GIE 61
Query: 171 DEKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKARG 230
K++REI I++ H H+++ EV++ IY+V+EY GE+ D I K +
Sbjct: 62 I-KVQREIKILRFLMHPHIIRQYEVIETPND--IYVVMEYVKSGELF----DYIVEKGK- 113
Query: 231 PPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXXXXXXX 290
L R +F+ ++ G+EY H I+HRD+KP N+LL +KI DFG+
Sbjct: 114 ---LQEDEARHLFQQIISGVEYCHRNMIVHRDLKPENVLLDSQCNIKIVDFGLSNVMHDG 170
Query: 291 XXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGITLH 350
+ G+P + APE+ + K + D DIW+ G+ L+
Sbjct: 171 HFLKT--------SCGSPNYAAPEVI----SGKPYGPD-----------VDIWSCGVILY 207
Query: 351 CLLFGMLPFISDYELELFDKIVNEPLVFEPYQKIEQCQVSQVECKEEYEEAQXXXXXXXX 410
LL G LPF + N P VFE KI++ + + A+
Sbjct: 208 ALLCGTLPFDDE----------NIPNVFE---KIKRGMYTLPNHLSHF--ARDLIPRMLM 252
Query: 411 XXXXXRMAIQDAKKHPWVCWDFNHNDYMSDQEKSLKLIEQSNFHRSPSEQVEQICIS--- 467
R++I + ++HPW FN++ + L I+Q+ + E++ Q ++
Sbjct: 253 VDPTMRISITEIRQHPW----FNNHLPLYLSIPPLDTIDQA---KKIEEEIIQNVVNIGF 305
Query: 468 --EHEVDTAVGGIGHKIKNAVGKFLPSTKSNDESNTNSV-NEFNDSGNNKYIDGCLNS 522
H VD+ I ++ A L D N NSV N+ S + DG NS
Sbjct: 306 DRNHVVDSLANRIQNEATVAYHLIL------DNRNQNSVPNDPFQSKFKEISDGIFNS 357
>At5g25110 [T] KOG0583 Serine/threonine protein kinase
Length = 460
Score = 117 bits (294), Expect = 7e-26
Identities = 85/283 (30%), Positives = 139/283 (49%), Gaps = 48/283 (16%)
Query: 101 LEYDPISKRKVLNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSN 160
+E + R + YE+ LG G GKV +++ T + VAIKI+N+ + +
Sbjct: 1 MEEEQQQLRVLFAKYEMGRLLGKGTFGKVYYGKEITTGESVAIKIINKDQVK-------- 52
Query: 161 RFKTPQSGIEDEKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEI--KW 218
+ G+ E+IKREI+IM+ H ++V+L EV+ A KI+ ++EY GE+ K
Sbjct: 53 -----REGMM-EQIKREISIMRLVRHPNIVELKEVM--ATKTKIFFIMEYVKGGELFSKI 104
Query: 219 CPGDVIETKARGPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKI 278
G + E AR + F+ ++ +++ H +G+ HRD+KP NLL+ E+G +K+
Sbjct: 105 VKGKLKEDSAR-----------KYFQQLISAVDFCHSRGVSHRDLKPENLLVDENGDLKV 153
Query: 279 SDFGVXXXXXXXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISF 338
SDFG+ GTPA+ APE+ ++K D
Sbjct: 154 SDFGLSALPEQILQDGLLHT-----QCGTPAYVAPEV------LRKKGYD--------GA 194
Query: 339 PTDIWAMGITLHCLLFGMLPFISDYELELFDKIVNEPLVFEPY 381
DIW+ GI L+ LL G LPF + ++++ KI + P+
Sbjct: 195 KGDIWSCGIILYVLLAGFLPFQDENLMKMYRKIFKSEFEYPPW 237
>At2g30360 [T] KOG0583 Serine/threonine protein kinase
Length = 435
Score = 117 bits (292), Expect = 1e-25
Identities = 107/352 (30%), Positives = 152/352 (42%), Gaps = 78/352 (22%)
Query: 115 YEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIEDEKI 174
YE+ + LG G KV ARD T Q VA+KI+N+ K T N +N I
Sbjct: 21 YELGKLLGCGAFAKVFHARDRRTGQSVAVKILNKKKLLT-NPALANN------------I 67
Query: 175 KREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKARGPPLL 234
KREI+IM++ H ++VKL EV+ A KI+ +E+ GE+ K L
Sbjct: 68 KREISIMRRLSHPNIVKLHEVM--ATKSKIFFAMEFVKGGELF--------NKISKHGRL 117
Query: 235 SFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXXXXXXXXXXX 294
S +R F+ ++ + Y H +G+ HRD+KP NLL+ E+G +K+SDFG+
Sbjct: 118 SEDLSRRYFQQLISAVGYCHARGVYHRDLKPENLLIDENGNLKVSDFGLSALTDQIRPDG 177
Query: 295 XXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGITLHCLLF 354
GTPA+ APEI SK+ D+W+ GI L L+
Sbjct: 178 LLHT-----LCGTPAYVAPEIL--------------SKKGYEGAKVDVWSCGIVLFVLVA 218
Query: 355 GMLPFISDYELELFDKIVNEPLVFEPYQKIEQCQVSQVECKEEYE-------EAQXXXXX 407
G LPF N+P V Y+KI K EY + +
Sbjct: 219 GYLPF-------------NDPNVMNMYKKI---------YKGEYRFPRWMSPDLKRFVSR 256
Query: 408 XXXXXXXXRMAIQDAKKHPW-VCWDFN----HNDYMSDQ--EKSLKLIEQSN 452
R+ I + K PW V F H+D + DQ E SL+ ++ N
Sbjct: 257 LLDINPETRITIDEILKDPWFVRGGFKQIKFHDDEIEDQKVESSLEAVKSLN 308
>YDR507c [D] KOG0588 Serine/threonine protein kinase
Length = 1142
Score = 116 bits (291), Expect = 2e-25
Identities = 95/322 (29%), Positives = 146/322 (44%), Gaps = 43/322 (13%)
Query: 105 PISKRKVLNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKT 164
P K + +++ E LG G GKV+LAR+ T Q A+K++++ T N ++ +
Sbjct: 9 PAIKDNTIGPWKLGETLGLGSTGKVQLARNGSTGQEAAVKVISKAVFNTGNVSGTSIVGS 68
Query: 165 PQSGIEDEKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVI 224
I+REI IMK +H +V++L +V + + +YLVLEY KGE+ ++
Sbjct: 69 TTPDALPYGIEREIIIMKLLNHPNVLRLYDVWET--NTDLYLVLEYAEKGELF---NLLV 123
Query: 225 ETKARGPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVX 284
E RGP L FR +++G+ Y H GI+HRD+KP NLLL +KI+DFG+
Sbjct: 124 E---RGP--LPEHEAIRFFRQIIIGVSYCHALGIVHRDLKPENLLLDHKYNIKIADFGMA 178
Query: 285 XXXXXXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWA 344
+ G+P + APEI S P F +D+W+
Sbjct: 179 ALETEGKLLET--------SCGSPHYAAPEIV--------------SGIPYQGFASDVWS 216
Query: 345 MGITLHCLLFGMLPFISDYELELFDKIVNEPLVFEPYQKIEQCQVSQVECKEEYEEAQXX 404
G+ L LL G LPF + D + L+ K+++ + E EAQ
Sbjct: 217 CGVILFALLTGRLPFDEE------DGNIRTLLL-----KVQKGEFEMPSDDEISREAQDL 265
Query: 405 XXXXXXXXXXXRMAIQDAKKHP 426
R+ +D KHP
Sbjct: 266 IRKILTVDPERRIKTRDILKHP 287
>CE27410 [T] KOG0583 Serine/threonine protein kinase
Length = 617
Score = 116 bits (291), Expect = 2e-25
Identities = 86/280 (30%), Positives = 133/280 (46%), Gaps = 42/280 (15%)
Query: 101 LEYDPISKRK---VLNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDK 157
+E++PI K+K ++ Y ++G G +GKVK D+ T A+KI+ K R +
Sbjct: 166 IEFEPIVKQKGPKIIEGYMWGGQIGTGSYGKVKECIDMYTLTRRAVKIMKYDKLRKITNG 225
Query: 158 FSNRFKTPQSGIEDEKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIK 217
+ N I+ E++I+++ +H +V+KLIE+ + K+Y+V EYC
Sbjct: 226 WEN-------------IRSEMSILRRMNHRNVIKLIEIFNIPAKGKVYMVFEYCI----- 267
Query: 218 WCPGDVIETKARGPPL-LSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIV 276
G V + P L+ + IF + GL YLH + + H+DIKP NLL+S D V
Sbjct: 268 ---GSVQQLLDMEPARRLTIGESHAIFIELCQGLNYLHSKRVSHKDIKPGNLLVSIDFTV 324
Query: 277 KISDFGVXXXXXXXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPII 336
KI DFGV K GTP F PE C+ + +
Sbjct: 325 KICDFGV-----AEQINLFQRDGRCTKVNGTPKFQPPE-CIY-----------GNHDFFD 367
Query: 337 SFPTDIWAMGITLHCLLFGMLPFISDYELELFDKIVNEPL 376
+ D+W+ G+TL+ L+ G PF L+L++ I EPL
Sbjct: 368 GYKADMWSAGVTLYNLVSGKYPFEKPVLLKLYECIGTEPL 407
>At4g24400 [T] KOG0583 Serine/threonine protein kinase
Length = 445
Score = 116 bits (291), Expect = 2e-25
Identities = 90/253 (35%), Positives = 121/253 (47%), Gaps = 50/253 (19%)
Query: 109 RKVLNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHK--KRTFNDKFSNRFKTPQ 166
RKV YE+ +G G KVK A++ T + VA+KIV+R KR D+
Sbjct: 4 RKV-GKYELGRTIGEGTFAKVKFAQNTETGESVAMKIVDRSTIIKRKMVDQ--------- 53
Query: 167 SGIEDEKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIET 226
IKREI+IMK H VV+L EVL A KIY++LEY + GE+ D I
Sbjct: 54 -------IKREISIMKLVRHPCVVRLYEVL--ASRTKIYIILEYITGGELF----DKIVR 100
Query: 227 KARGPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXXX 286
R LS R+ F ++ G++Y H +G+ HRD+KP NLLL G +KISDFG+
Sbjct: 101 NGR----LSESEARKYFHQLIDGVDYCHSKGVYHRDLKPENLLLDSQGNLKISDFGLSAL 156
Query: 287 XXXXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMG 346
T GTP + APE+ S + DIW+ G
Sbjct: 157 PEQGVTILKT-------TCGTPNYVAPEVL--------------SHKGYNGAVADIWSCG 195
Query: 347 ITLHCLLFGMLPF 359
+ L+ L+ G LPF
Sbjct: 196 VILYVLMAGYLPF 208
>At5g01810 [T] KOG0583 Serine/threonine protein kinase
Length = 421
Score = 115 bits (288), Expect = 4e-25
Identities = 86/259 (33%), Positives = 124/259 (47%), Gaps = 48/259 (18%)
Query: 115 YEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIEDEKI 174
YE+ + LG G KV AR L T VAIK+++ K+R + E+I
Sbjct: 12 YEVGKFLGQGTFAKVYHARHLKTGDSVAIKVID--KERILKVGMT------------EQI 57
Query: 175 KREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEI--KWCPGDVIETKARGPP 232
KREI+ M+ H ++V+L EV+ A KIY V+E+ GE+ K G + E AR
Sbjct: 58 KREISAMRLLRHPNIVELHEVM--ATKSKIYFVMEHVKGGELFNKVSTGKLREDVAR--- 112
Query: 233 LLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXXXXXXXXX 292
+ F+ ++ +++ H +G+ HRD+KP NLLL E G +KISDFG+
Sbjct: 113 --------KYFQQLVRAVDFCHSRGVCHRDLKPENLLLDEHGNLKISDFGLSALSDSRRQ 164
Query: 293 XXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGITLHCL 352
T GTPA+ APE+ S+ F D+W+ G+ L L
Sbjct: 165 DGLLHT-----TCGTPAYVAPEVI--------------SRNGYDGFKADVWSCGVILFVL 205
Query: 353 LFGMLPFISDYELELFDKI 371
L G LPF +EL+ KI
Sbjct: 206 LAGYLPFRDSNLMELYKKI 224
>7294217 [D] KOG0588 Serine/threonine protein kinase
Length = 851
Score = 115 bits (288), Expect = 4e-25
Identities = 95/317 (29%), Positives = 139/317 (42%), Gaps = 68/317 (21%)
Query: 115 YEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIEDEKI 174
Y + + LG GQ G VKL V + VAIKI+NR K S K+
Sbjct: 18 YRLEKTLGKGQTGLVKLGVHCVIGKKVAIKIINREKL---------------SESVLMKV 62
Query: 175 KREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKARGPPLL 234
+REIAIMK H HV+ L +V ++ K +YL+LE+ S GE+ D + K R P
Sbjct: 63 EREIAIMKLIDHPHVLGLSDVYENKKY--LYLILEHVSGGELF----DYLVKKGRLTP-- 114
Query: 235 SFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXXXXXXXXXXX 294
+ R+ FR ++ L++ H I HRD+KP NLLL E +KI+DFG+
Sbjct: 115 --KEARKFFRQIISALDFCHSHSICHRDLKPENLLLDEKNNIKIADFGMASLQPAGSMLE 172
Query: 295 XXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGITLHCLLF 354
+ G+P + PE+ E K+D D+W+ G+ L+ LL
Sbjct: 173 T--------SCGSPHYACPEVIRGE----KYD----------GRKADVWSCGVILYALLV 210
Query: 355 GMLPFISDYELELFDKIVNEPLVFEPYQKIEQCQV---SQVECKEEYEEAQXXXXXXXXX 411
G LPF D +L +K V + P+ CQ +E +
Sbjct: 211 GALPFDDDNLRQLLEK-VKRGVFHIPHFVPPDCQSLLRGMIEVNPD-------------- 255
Query: 412 XXXXRMAIQDAKKHPWV 428
R+ + + +HPWV
Sbjct: 256 ---RRLTLAEINRHPWV 269
>At2g25090 [T] KOG0583 Serine/threonine protein kinase
Length = 469
Score = 114 bits (285), Expect = 8e-25
Identities = 86/281 (30%), Positives = 135/281 (47%), Gaps = 39/281 (13%)
Query: 107 SKRKVLNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQ 166
S + + Y I LG G KV ++ T VAIK++ + + F R
Sbjct: 7 SSTVLFDKYNIGRLLGTGNFAKVYHGTEISTGDDVAIKVIKK------DHVFKRRGMM-- 58
Query: 167 SGIEDEKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIET 226
E+I+REIA+M+ H +VV+L EV+ A +KI+ V+EY + GE+ ++I+
Sbjct: 59 -----EQIEREIAVMRLLRHPNVVELREVM--ATKKKIFFVMEYVNGGELF----EMIDR 107
Query: 227 KARGPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXXX 286
+ P L+ R+ F+ ++ +++ H +G+ HRDIKP NLLL +G +K++DFG+
Sbjct: 108 DGKLPEDLA----RKYFQQLISAVDFCHSRGVFHRDIKPENLLLDGEGDLKVTDFGLSAL 163
Query: 287 X--XXXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWA 344
GTPA+ APE+ K +D DIW+
Sbjct: 164 MMPEGLGGRRGSSDDLLHTRCGTPAYVAPEVL----RNKGYD----------GAMADIWS 209
Query: 345 MGITLHCLLFGMLPFISDYELELFDKIVNEPLVFEPYQKIE 385
GI L+ LL G LPFI + + L+ KI F P+ +E
Sbjct: 210 CGIVLYALLAGFLPFIDENVMTLYTKIFKAECEFPPWFSLE 250
>Hs5453964 [T] KOG0583 Serine/threonine protein kinase
Length = 550
Score = 114 bits (284), Expect = 1e-24
Identities = 103/382 (26%), Positives = 165/382 (42%), Gaps = 65/382 (17%)
Query: 109 RKVLNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSG 168
R + Y + + LG G GKVK+ + +T VA+KI+NR K R+ +
Sbjct: 12 RVKIGHYILGDTLGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVV----------- 60
Query: 169 IEDEKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKA 228
KI+REI +K H H++KL +V+ I++V+EY S GE+ D I
Sbjct: 61 ---GKIRREIQNLKLFRHPHIIKLYQVISTPSD--IFMVMEYVSGGELF----DYICKNG 111
Query: 229 RGPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXXXXX 288
R L + +R +F+ +L G++Y H ++HRD+KP N+LL KI+DFG+
Sbjct: 112 R----LDEKESRRLFQQILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMS 167
Query: 289 XXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGIT 348
+ G+P + APE+ S DIW+ G+
Sbjct: 168 DGEFLRT--------SCGSPNYAAPEVI--------------SGRLYAGPEVDIWSSGVI 205
Query: 349 LHCLLFGMLPFISDYELELFDKIVNEPLVFEPYQKIEQCQVSQVECKEEYEEAQXXXXXX 408
L+ LL G LPF D+ LF KI + +F Q + +S ++ + + +
Sbjct: 206 LYALLCGTLPFDDDHVPTLFKKICDG--IFYTPQYLNPSVISLLKHMLQVDPMK------ 257
Query: 409 XXXXXXXRMAIQDAKKHPWVCWDFNHNDYMSDQEKSLKLIEQSNFHRSPSEQVEQICISE 468
R +I+D ++H W D + D S +I+ + E E+ SE
Sbjct: 258 -------RASIKDIREHEWFKQDLPKYLFPEDPSYSSTMIDD----EALKEVCEKFECSE 306
Query: 469 HEVDTAVGGIGHKIKNAVGKFL 490
EV + + H+ AV L
Sbjct: 307 EEVLSCLYNRNHQDPLAVAYHL 328
>CE17284 [T] KOG0583 Serine/threonine protein kinase
Length = 726
Score = 114 bits (284), Expect = 1e-24
Identities = 85/276 (30%), Positives = 133/276 (47%), Gaps = 46/276 (16%)
Query: 106 ISKRKVLNT-YEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKT 164
+SK +VL Y + +ELG G GKV+LA L+T Q VAIKI+++
Sbjct: 1 MSKYEVLQGFYAVHDELGSGGFGKVRLATHLLTNQKVAIKIIDKK--------------- 45
Query: 165 PQSGIEDEKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVI 224
Q G + +++ E+ ++ H+++ +L ++ K ++V+EYCS GE+ D I
Sbjct: 46 -QLGHDLPRVQTEMDALRNLSHQNICRLYHYIETED--KFFIVMEYCSGGEMF----DYI 98
Query: 225 ETKARGPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVX 284
K R L R FR ++ + ++H QG HRD+KP NLLL+ED +K+ DFG+
Sbjct: 99 VRKER----LEESEARHFFRQLVSAIAFVHSQGYAHRDLKPENLLLTEDLHLKLIDFGLC 154
Query: 285 XXXXXXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWA 344
G+PA+ APE+ I+ N D+W+
Sbjct: 155 AKTEKGRIDKHNLDT----CCGSPAYAAPEL------IQGLQYKGNE--------ADVWS 196
Query: 345 MGITLHCLLFGMLPFISDYELELFDKIVNEPLVFEP 380
MGI L+ LL G LPF D +++ K + +EP
Sbjct: 197 MGILLYTLLVGALPF-EDDNMQIMYKKIQSGCFYEP 231
>CE27768 [R] KOG0586 Serine/threonine protein kinase
Length = 1096
Score = 113 bits (283), Expect = 1e-24
Identities = 79/258 (30%), Positives = 130/258 (49%), Gaps = 47/258 (18%)
Query: 115 YEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIEDEKI 174
Y++++ +G G KVKLA+ ++T VAIKI++ KT + +K+
Sbjct: 122 YKLLKTIGKGNFAKVKLAKHVITGHEVAIKIID---------------KTALNPSSLQKL 166
Query: 175 KREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKARGPPLL 234
RE+ IMK+ H ++VKL +V++ ++ +YLVLEY S GE+ D + R +
Sbjct: 167 FREVKIMKQLDHPNIVKLYQVMETEQT--LYLVLEYASGGEVF----DYLVAHGR----M 216
Query: 235 SFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXXXXXXXXXXX 294
+ R FR ++ ++YLH + IIHRD+K NLLL +D +KI+DFG
Sbjct: 217 KEKEARAKFRQIVSAVQYLHSKNIIHRDLKAENLLLDQDMNIKIADFGFSNTFSLGNKLD 276
Query: 295 XXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGITLHCLLF 354
G+P + APE+ + KK+D D+W++G+ L+ L+
Sbjct: 277 TF--------CGSPPYAAPELF----SGKKYD----------GPEVDVWSLGVILYTLVS 314
Query: 355 GMLPFISDYELELFDKIV 372
G LPF EL ++++
Sbjct: 315 GSLPFDGQNLKELRERVL 332
>CE23838 [R] KOG0586 Serine/threonine protein kinase
Length = 1192
Score = 113 bits (283), Expect = 1e-24
Identities = 79/258 (30%), Positives = 130/258 (49%), Gaps = 47/258 (18%)
Query: 115 YEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIEDEKI 174
Y++++ +G G KVKLA+ ++T VAIKI++ KT + +K+
Sbjct: 170 YKLLKTIGKGNFAKVKLAKHVITGHEVAIKIID---------------KTALNPSSLQKL 214
Query: 175 KREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKARGPPLL 234
RE+ IMK+ H ++VKL +V++ ++ +YLVLEY S GE+ D + R +
Sbjct: 215 FREVKIMKQLDHPNIVKLYQVMETEQT--LYLVLEYASGGEVF----DYLVAHGR----M 264
Query: 235 SFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXXXXXXXXXXX 294
+ R FR ++ ++YLH + IIHRD+K NLLL +D +KI+DFG
Sbjct: 265 KEKEARAKFRQIVSAVQYLHSKNIIHRDLKAENLLLDQDMNIKIADFGFSNTFSLGNKLD 324
Query: 295 XXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGITLHCLLF 354
G+P + APE+ + KK+D D+W++G+ L+ L+
Sbjct: 325 TF--------CGSPPYAAPELF----SGKKYD----------GPEVDVWSLGVILYTLVS 362
Query: 355 GMLPFISDYELELFDKIV 372
G LPF EL ++++
Sbjct: 363 GSLPFDGQNLKELRERVL 380
>At2g26980 [T] KOG0583 Serine/threonine protein kinase
Length = 441
Score = 113 bits (283), Expect = 1e-24
Identities = 85/264 (32%), Positives = 128/264 (48%), Gaps = 44/264 (16%)
Query: 108 KRKVLNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQS 167
KR+V YE+ +G G KVK AR+ T + VA+KI++ K++ K +
Sbjct: 8 KRRV-GKYEVGRTIGEGTFAKVKFARNSETGEPVALKILD--KEKVLKHKMA-------- 56
Query: 168 GIEDEKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETK 227
E+I+REIA MK H +VV+L EV+ A KI+++LEY + GE+ D I
Sbjct: 57 ----EQIRREIATMKLIKHPNVVQLYEVM--ASKTKIFIILEYVTGGELF----DKIVND 106
Query: 228 ARGPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXXXX 287
R + R F+ ++ ++Y H +G+ HRD+KP NLLL G +KISDFG+
Sbjct: 107 GR----MKEDEARRYFQQLIHAVDYCHSRGVYHRDLKPENLLLDSYGNLKISDFGLSALS 162
Query: 288 XXXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGI 347
+ GTP + APE+ + +D D+W+ G+
Sbjct: 163 QQVRDDGLLHT-----SCGTPNYVAPEVL----NDRGYD----------GATADMWSCGV 203
Query: 348 TLHCLLFGMLPFISDYELELFDKI 371
L+ LL G LPF + L+ KI
Sbjct: 204 VLYVLLAGYLPFDDSNLMNLYKKI 227
>At1g30270 [T] KOG0583 Serine/threonine protein kinase
Length = 480
Score = 113 bits (283), Expect = 1e-24
Identities = 83/273 (30%), Positives = 126/273 (45%), Gaps = 45/273 (16%)
Query: 109 RKVLNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSG 168
R + YE+ LG G KVK AR++ VAIK+++ K++ +K
Sbjct: 25 RTRVGKYELGRTLGEGTFAKVKFARNVENGDNVAIKVID--KEKVLKNKMI--------- 73
Query: 169 IEDEKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKA 228
+IKREI+ MK H +V+++ EV+ A KIY VLE+ + GE+ D I +
Sbjct: 74 ---AQIKREISTMKLIKHPNVIRMFEVM--ASKTKIYFVLEFVTGGELF----DKISSNG 124
Query: 229 RGPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXXXXX 288
R L R+ F+ ++ ++Y H +G+ HRD+KP NLLL +G +K+SDFG+
Sbjct: 125 R----LKEDEARKYFQQLINAVDYCHSRGVYHRDLKPENLLLDANGALKVSDFGLSALPQ 180
Query: 289 XXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGIT 348
T GTP + APE+ K +D D+W+ G+
Sbjct: 181 QEDGLLHT-------TCGTPNYVAPEVI----NNKGYD----------GAKADLWSCGVI 219
Query: 349 LHCLLFGMLPFISDYELELFDKIVNEPLVFEPY 381
L L+ G LPF L+ KI P+
Sbjct: 220 LFVLMAGYLPFEDSNLTSLYKKIFKAEFTCPPW 252
>At4g30960 [T] KOG0583 Serine/threonine protein kinase
Length = 441
Score = 113 bits (282), Expect = 2e-24
Identities = 82/259 (31%), Positives = 125/259 (47%), Gaps = 48/259 (18%)
Query: 115 YEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIEDEKI 174
YE+ LGHG KV AR++ T + VA+K+V + K + G+ D+ I
Sbjct: 24 YELGRLLGHGTFAKVYHARNIQTGKSVAMKVVGKEK-------------VVKVGMVDQ-I 69
Query: 175 KREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEI--KWCPGDVIETKARGPP 232
KREI++M+ H ++V+L EV+ A KIY +E GE+ K G + E AR
Sbjct: 70 KREISVMRMVKHPNIVELHEVM--ASKSKIYFAMELVRGGELFAKVAKGRLREDVAR--- 124
Query: 233 LLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXXXXXXXXX 292
F+ ++ +++ H +G+ HRD+KP NLLL E+G +K++DFG+
Sbjct: 125 --------VYFQQLISAVDFCHSRGVYHRDLKPENLLLDEEGNLKVTDFGLSAFTEHLKQ 176
Query: 293 XXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGITLHCL 352
T GTPA+ APE+ L K+ D+W+ G+ L L
Sbjct: 177 DGLLHT-----TCGTPAYVAPEVIL--------------KKGYDGAKADLWSCGVILFVL 217
Query: 353 LFGMLPFISDYELELFDKI 371
L G LPF D + ++ KI
Sbjct: 218 LAGYLPFQDDNLVNMYRKI 236
>7290150 [T] KOG0583 Serine/threonine protein kinase
Length = 582
Score = 112 bits (279), Expect = 4e-24
Identities = 103/394 (26%), Positives = 165/394 (41%), Gaps = 74/394 (18%)
Query: 121 LGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIEDEKIKREIAI 180
LG G GKVK+ +T+ VA+KI+NR K ++ + KI+REI
Sbjct: 34 LGTGTFGKVKIGEHQITRVKVAVKILNRQKIKSLDVV--------------GKIRREIQN 79
Query: 181 MKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKARGPPLLSFQRTR 240
+K H H++KL +V+ I++++EY S GE+ D I + L + R
Sbjct: 80 LKLFRHPHIIKLYQVISTPSD--IFMIMEYVSGGELF----DYIVKHGK----LQEHQAR 129
Query: 241 EIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXXXXXXXXXXXXXXXXX 300
F+ ++ G++Y H I+HRD+KP NLLL + VKI+DFG+
Sbjct: 130 RFFQQIISGVDYCHRHMIVHRDLKPENLLLDHNMHVKIADFGLSNMMLDGEFLRT----- 184
Query: 301 XAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGITLHCLLFGMLPFI 360
+ G+P + APE+ S + DIW+ G+ L+ LL G LPF
Sbjct: 185 ---SCGSPNYAAPEVI--------------SGKLYAGPEVDIWSCGVILYALLCGTLPFD 227
Query: 361 SDYELELFDKIVNEPLVFEPYQKIE----QCQVSQVECKEEYEEAQXXXXXXXXXXXXXR 416
++ LF KI + Y + CQ+ QV+ R
Sbjct: 228 DEHVPTLFRKIKSGIFPIPEYLNKQVVNLVCQMLQVD-------------------PLKR 268
Query: 417 MAIQDAKKHPWVCWDFNHNDYMSDQEKSLKLIEQSNFHRSPSEQVEQICISEHEV-DTAV 475
I++ KKH W D + S E+ +I+ + +E + + E EV ++ +
Sbjct: 269 ANIEEIKKHEWFQKDLPAYLFPSSIEQDSNVIDT----YAVAEVCTKFGVKETEVHNSLL 324
Query: 476 GGIGHKIKNAVGKFLPSTKSNDESNTNSVNEFND 509
G H + K + N +NE N+
Sbjct: 325 SGDPHDQLAIAYHLIIDNKRFADDAANQINEINN 358
>Hs9845489 [R] KOG0586 Serine/threonine protein kinase
Length = 691
Score = 111 bits (277), Expect = 7e-24
Identities = 78/261 (29%), Positives = 128/261 (48%), Gaps = 47/261 (18%)
Query: 112 LNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIED 171
+ Y +++ +G G KVKLAR ++T + VA+KI++ KT +
Sbjct: 17 IGNYRLLKTIGKGNFAKVKLARHILTGKEVAVKIID---------------KTQLNSSSL 61
Query: 172 EKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKARGP 231
+K+ RE+ IMK +H ++VKL EV++ K+ +YLV+EY S GE+ D + R
Sbjct: 62 QKLFREVRIMKVLNHPNIVKLFEVIETEKT--LYLVMEYASGGEVF----DYLVAHGR-- 113
Query: 232 PLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXXXXXXXX 291
+ + R FR ++ ++Y H + I+HRD+K NLLL D +KI+DFG
Sbjct: 114 --MKEKEARAKFRQIVSAVQYCHQKFIVHRDLKAENLLLDADMNIKIADFGFSNEFTFGN 171
Query: 292 XXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGITLHC 351
G+P + APE+ KK+D D+W++G+ L+
Sbjct: 172 KLDTF--------CGSPPYAAPELF----QGKKYD----------GPEVDVWSLGVILYT 209
Query: 352 LLFGMLPFISDYELELFDKIV 372
L+ G LPF EL ++++
Sbjct: 210 LVSGSLPFDGQNLKELRERVL 230
>Hs9845487 [R] KOG0586 Serine/threonine protein kinase
Length = 745
Score = 111 bits (277), Expect = 7e-24
Identities = 78/261 (29%), Positives = 128/261 (48%), Gaps = 47/261 (18%)
Query: 112 LNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIED 171
+ Y +++ +G G KVKLAR ++T + VA+KI++ KT +
Sbjct: 17 IGNYRLLKTIGKGNFAKVKLARHILTGKEVAVKIID---------------KTQLNSSSL 61
Query: 172 EKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKARGP 231
+K+ RE+ IMK +H ++VKL EV++ K+ +YLV+EY S GE+ D + R
Sbjct: 62 QKLFREVRIMKVLNHPNIVKLFEVIETEKT--LYLVMEYASGGEVF----DYLVAHGR-- 113
Query: 232 PLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXXXXXXXX 291
+ + R FR ++ ++Y H + I+HRD+K NLLL D +KI+DFG
Sbjct: 114 --MKEKEARAKFRQIVSAVQYCHQKFIVHRDLKAENLLLDADMNIKIADFGFSNEFTFGN 171
Query: 292 XXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGITLHC 351
G+P + APE+ KK+D D+W++G+ L+
Sbjct: 172 KLDTF--------CGSPPYAAPELF----QGKKYD----------GPEVDVWSLGVILYT 209
Query: 352 LLFGMLPFISDYELELFDKIV 372
L+ G LPF EL ++++
Sbjct: 210 LVSGSLPFDGQNLKELRERVL 230
>Hs22062450 [R] KOG0586 Serine/threonine protein kinase
Length = 787
Score = 111 bits (277), Expect = 7e-24
Identities = 78/261 (29%), Positives = 128/261 (48%), Gaps = 47/261 (18%)
Query: 112 LNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIED 171
+ Y +++ +G G KVKLAR ++T + VA+KI++ KT +
Sbjct: 50 IGNYRLLKTIGKGNFAKVKLARHILTGKEVAVKIID---------------KTQLNSSSL 94
Query: 172 EKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKARGP 231
+K+ RE+ IMK +H ++VKL EV++ K+ +YLV+EY S GE+ D + R
Sbjct: 95 QKLFREVRIMKVLNHPNIVKLFEVIETEKT--LYLVMEYASGGEVF----DYLVAHGR-- 146
Query: 232 PLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXXXXXXXX 291
+ + R FR ++ ++Y H + I+HRD+K NLLL D +KI+DFG
Sbjct: 147 --MKEKEARAKFRQIVSAVQYCHQKFIVHRDLKAENLLLDADMNIKIADFGFSNEFTFGN 204
Query: 292 XXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGITLHC 351
G+P + APE+ KK+D D+W++G+ L+
Sbjct: 205 KLDTF--------CGSPPYAAPELF----QGKKYD----------GPEVDVWSLGVILYT 242
Query: 352 LLFGMLPFISDYELELFDKIV 372
L+ G LPF EL ++++
Sbjct: 243 LVSGSLPFDGQNLKELRERVL 263
>Hs13899225 [R] KOG0586 Serine/threonine protein kinase
Length = 688
Score = 111 bits (277), Expect = 7e-24
Identities = 79/261 (30%), Positives = 127/261 (48%), Gaps = 47/261 (18%)
Query: 112 LNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIED 171
+ Y ++ +G G KVKLAR ++T + VAIKI++ KT +
Sbjct: 56 VGNYRLLRTIGKGNSAKVKLARHILTGREVAIKIID---------------KTQLNPSSL 100
Query: 172 EKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKARGP 231
+K+ RE+ IMK +H ++VKL EV++ K+ +YLV+EY S GE+ D + + R
Sbjct: 101 QKLFREVRIMKGLNHPNIVKLFEVIETEKT--LYLVMEYASAGEVF----DYLVSHGR-- 152
Query: 232 PLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXXXXXXXX 291
+ + R FR ++ + Y H + I+HRD+K NLLL + +KI+DFG
Sbjct: 153 --MKEKEARAKFRQIVSAVHYCHQKNIVHRDLKAENLLLDAEANIKIADFGFSNEFTLGS 210
Query: 292 XXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGITLHC 351
G+P + APE+ KK+D DIW++G+ L+
Sbjct: 211 KLDTF--------CGSPPYAAPELF----QGKKYD----------GPEVDIWSLGVILYT 248
Query: 352 LLFGMLPFISDYELELFDKIV 372
L+ G LPF EL ++++
Sbjct: 249 LVSGSLPFDGHNLKELRERVL 269
>At4g14580 [T] KOG0583 Serine/threonine protein kinase
Length = 426
Score = 110 bits (276), Expect = 9e-24
Identities = 86/269 (31%), Positives = 126/269 (45%), Gaps = 44/269 (16%)
Query: 104 DPISKRKVLNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFK 163
+ I+ +L YE+ LG G KV +AR + T +LVAIKI+++ K
Sbjct: 10 EKITGTVLLGKYELGRRLGSGSFAKVHVARSISTGELVAIKIIDKQK------------- 56
Query: 164 TPQSGIEDEKIKREIAIMKKCH-HEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGD 222
T SG+E +I REI M++ H H +V+K+ EV+ A KIYLV+EY + GE+
Sbjct: 57 TIDSGMEP-RIIREIEAMRRLHNHPNVLKIHEVM--ATKSKIYLVVEYAAGGELF----- 108
Query: 223 VIETKARGPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFG 282
TK L+ R F+ + L + H GI HRD+KP NLLL + G +K+SDFG
Sbjct: 109 ---TKLIRFGRLNESAARRYFQQLASALSFCHRDGIAHRDVKPQNLLLDKQGNLKVSDFG 165
Query: 283 VXXXXXXXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDI 342
+ GTPA+ APE+ ++ D
Sbjct: 166 LSALPEHRSNNGLLHT-----ACGTPAYTAPEVI--------------AQRGYDGAKADA 206
Query: 343 WAMGITLHCLLFGMLPFISDYELELFDKI 371
W+ G+ L LL G +PF + ++ KI
Sbjct: 207 WSCGVFLFVLLAGYVPFDDANIVAMYRKI 235
>Hs13569922 [R] KOG0611 Predicted serine/threonine protein kinase
Length = 628
Score = 110 bits (274), Expect = 1e-23
Identities = 84/325 (25%), Positives = 144/325 (43%), Gaps = 63/325 (19%)
Query: 108 KRKVLNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQS 167
K + + YE +E LG G +GKVK AR+ + +LVAIK + + K + D
Sbjct: 46 KHNLRHRYEFLETLGKGTYGKVKKARES-SGRLVAIKSIRKDKIKDEQDLMH-------- 96
Query: 168 GIEDEKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETK 227
I+REI IM +H H++ + EV ++ S KI +V+EY S+G++ D I +
Sbjct: 97 ------IRREIEIMSSLNHPHIIAIHEVFEN--SSKIVIVMEYASRGDLY----DYISER 144
Query: 228 ARGPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXXXX 287
+ LS + R FR ++ + Y H ++HRD+K N+LL +G +KI+DFG+
Sbjct: 145 QQ----LSEREARHFFRQIVSAVHYCHQNRVVHRDLKLENILLDANGNIKIADFGLSNLY 200
Query: 288 XXXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGI 347
G+P + +PEI + +P D W++G+
Sbjct: 201 HQGKFLQTF--------CGSPLYASPEIV--------------NGKPYTGPEVDSWSLGV 238
Query: 348 TLHCLLFGMLPFISDYELELFDKIVNEPLVFEPYQKIEQCQVSQVECKEEYEEAQXXXXX 407
L+ L+ G +PF ++ ++ K ++ EP + + C + +
Sbjct: 239 LLYILVHGTMPF-DGHDHKILVKQISNGAYREPPKPSDACGLIR---------------W 282
Query: 408 XXXXXXXXRMAIQDAKKHPWVCWDF 432
R ++D H WV W +
Sbjct: 283 LLMVNPTRRATLEDVASHWWVNWGY 307
>At5g35410 [T] KOG0583 Serine/threonine protein kinase
Length = 446
Score = 110 bits (274), Expect = 1e-23
Identities = 98/321 (30%), Positives = 143/321 (44%), Gaps = 62/321 (19%)
Query: 108 KRKVLNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQS 167
K + + YE+ +G G KVK AR+ T VAIKI+ + + NR
Sbjct: 4 KMRRVGKYEVGRTIGEGTFAKVKFARNTDTGDNVAIKIMAK------STILKNRMV---- 53
Query: 168 GIEDEKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETK 227
++IKREI+IMK H ++V+L EVL A KIY+VLE+ + GE+ D I K
Sbjct: 54 ----DQIKREISIMKIVRHPNIVRLYEVL--ASPSKIYIVLEFVTGGELF----DRIVHK 103
Query: 228 ARGPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXXXX 287
R L +R+ F+ ++ + + H +G+ HRD+KP NLLL +G +K+SDFG+
Sbjct: 104 GR----LEESESRKYFQQLVDAVAHCHCKGVYHRDLKPENLLLDTNGNLKVSDFGLSALP 159
Query: 288 XXXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGI 347
T GTP + APE+ S + DIW+ G+
Sbjct: 160 QEGVELLRT-------TCGTPNYVAPEVL--------------SGQGYDGSAADIWSCGV 198
Query: 348 TLHCLLFGMLPFISDYELELFDKIVNEPLVFEPYQKIEQCQVSQVECKEEYE-EAQXXXX 406
L +L G LPF S+ +L Y+KI + S C + E +
Sbjct: 199 ILFVILAGYLPF-SETDLPGL------------YRKINAAEFS---CPPWFSAEVKFLIH 242
Query: 407 XXXXXXXXXRMAIQDAKKHPW 427
R+ IQ KK PW
Sbjct: 243 RILDPNPKTRIQIQGIKKDPW 263
>SPCC74.03c [T] KOG0583 Serine/threonine protein kinase
Length = 576
Score = 109 bits (273), Expect = 2e-23
Identities = 95/341 (27%), Positives = 150/341 (43%), Gaps = 67/341 (19%)
Query: 104 DPISKRKVLNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFK 163
+ ISKR + Y I E LG G GKVKLA T+Q VA+K ++R + +
Sbjct: 24 EAISKRHI-GPYIIRETLGEGSFGKVKLATHYKTQQKVALKFISRQLLKKSDMHM----- 77
Query: 164 TPQSGIEDEKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDV 223
+++REI+ +K H H++KL +V+ I +V+EY GE+ D
Sbjct: 78 ---------RVEREISYLKLLRHPHIIKLYDVITTPTD--IVMVIEYAG-GELF----DY 121
Query: 224 IETKARGPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGV 283
I K R ++ R F+ ++ +EY H I+HRD+KP NLLL ++ VKI+DFG+
Sbjct: 122 IVEKKR----MTEDEGRRFFQQIICAIEYCHRHKIVHRDLKPENLLLDDNLNVKIADFGL 177
Query: 284 XXXXXXXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFP-TDI 342
+ G+P + APE+ N K + + P D+
Sbjct: 178 SNIMTDGNFLKT--------SCGSPNYAAPEVI-------------NGK--LYAGPEVDV 214
Query: 343 WAMGITLHCLLFGMLPFISDYELELFDKIVNEPLVFEPYQKIEQCQVSQVECKEEYEEAQ 402
W+ GI L+ +L G LPF ++ LF K+ + V + AQ
Sbjct: 215 WSCGIVLYVMLVGRLPFDDEFIPNLFKKVNSCVYVMPDFLS---------------PGAQ 259
Query: 403 XXXXXXXXXXXXXRMAIQDAKKHPWVCWDFNHNDYMSDQEK 443
R+ IQ+ ++ PW ++ N DY+ E+
Sbjct: 260 SLIRRMIVADPMQRITIQEIRRDPW--FNVNLPDYLRPMEE 298
>HsM4505103 [R] KOG0586 Serine/threonine protein kinase
Length = 713
Score = 109 bits (273), Expect = 2e-23
Identities = 77/261 (29%), Positives = 128/261 (48%), Gaps = 47/261 (18%)
Query: 112 LNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIED 171
+ Y +++ +G G KVKLAR ++T + VAIKI++ KT +
Sbjct: 53 IGNYRLLKTIGKGNFAKVKLARHILTGREVAIKIID---------------KTQLNPTSL 97
Query: 172 EKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKARGP 231
+K+ RE+ IMK +H ++VKL EV++ K+ +YL++EY S G++ D + R
Sbjct: 98 QKLFREVRIMKILNHPNIVKLFEVIETQKT--LYLIMEYASGGKVF----DYLVAHGR-- 149
Query: 232 PLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXXXXXXXX 291
+ + R FR ++ ++Y H + I+HRD+K NLLL D +KI+DFG
Sbjct: 150 --MKEKEARSKFRQIVSAVQYCHQKRIVHRDLKAENLLLDADMNIKIADFGFSNEFTVGG 207
Query: 292 XXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGITLHC 351
G+P + APE+ KK+D D+W++G+ L+
Sbjct: 208 KLDTF--------CGSPPYAAPELF----QGKKYD----------GPEVDVWSLGVILYT 245
Query: 352 LLFGMLPFISDYELELFDKIV 372
L+ G LPF EL ++++
Sbjct: 246 LVSGSLPFDGQNLKELRERVL 266
>CE07458 [T] KOG0583 Serine/threonine protein kinase
Length = 562
Score = 109 bits (273), Expect = 2e-23
Identities = 104/405 (25%), Positives = 171/405 (41%), Gaps = 73/405 (18%)
Query: 115 YEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIEDEKI 174
Y + E LG G GKVK+ T+ VA+KI+NR K ++ + KI
Sbjct: 25 YILKETLGVGTFGKVKVGIHETTQYKVAVKILNRQKIKSLDVV--------------GKI 70
Query: 175 KREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKARGPPLL 234
+REI + H H+++L +V+ I++++E+ S GE+ D I R L
Sbjct: 71 RREIQNLSLFRHPHIIRLYQVISTPSD--IFMIMEHVSGGELF----DYIVKHGR----L 120
Query: 235 SFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXXXXXXXXXXX 294
R F+ ++ G++Y H ++HRD+KP NLLL E VKI+DFG+
Sbjct: 121 KTAEARRFFQQIISGVDYCHRHMVVHRDLKPENLLLDEQNNVKIADFGLSNIMTDGDFLR 180
Query: 295 XXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGITLHCLLF 354
+ G+P + APE+ S + D+W+ G+ L+ LL
Sbjct: 181 T--------SCGSPNYAAPEVI--------------SGKLYAGPEVDVWSCGVILYALLC 218
Query: 355 GMLPFISDYELELFDKIVNEPLVFEPYQKIEQCQVSQVE---CKEEYEEAQXXXXXXXXX 411
G LPF ++ LF KI + VF +E+ V+ + C + +
Sbjct: 219 GTLPFDDEHVPSLFRKIKSG--VFPTPDFLERPIVNLLHHMLCVDPMK------------ 264
Query: 412 XXXXRMAIQDAKKHPWVCWDFNHNDYMSDQEKSLKLIEQSNFHRSPSEQVEQICISEHEV 471
R I+D H W D + + E +++ + E E+ ++E EV
Sbjct: 265 ----RATIKDVIAHEWFQKDLPNYLFPPINESEASIVD----IEAVREVTERYHVAEEEV 316
Query: 472 DTAVGGIG--HKIKNAVGKFLPSTKSNDESNTNSVNEFNDSGNNK 514
+A+ G H + A + + + DE+ S+ EF NK
Sbjct: 317 TSALLGDDPHHHLSIAYNLIVDNKRIADETAKLSIEEFYQVTPNK 361
>At5g58380 [T] KOG0583 Serine/threonine protein kinase
Length = 464
Score = 109 bits (272), Expect = 3e-23
Identities = 79/257 (30%), Positives = 123/257 (47%), Gaps = 44/257 (17%)
Query: 115 YEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIEDEKI 174
Y++ LG G KV R ++T Q VAIK++++ K + G+ E+I
Sbjct: 12 YDVGRLLGQGTFAKVYYGRSILTNQSVAIKMIDKEK-------------VMKVGLI-EQI 57
Query: 175 KREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKARGPPLL 234
KREI++M+ H +VV+L EV+ A +IY V+EYC GE+ V + K R
Sbjct: 58 KREISVMRIARHPNVVELYEVM--ATKTRIYFVMEYCKGGELF---NKVAKGKLRDDVAW 112
Query: 235 SFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXXXXXXXXXXX 294
+ F ++ +++ H + + HRDIKP NLLL ++ +K+SDFG+
Sbjct: 113 KY------FYQLINAVDFCHSREVYHRDIKPENLLLDDNENLKVSDFGLSALADCKRQDG 166
Query: 295 XXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGITLHCLLF 354
T GTPA+ APE+ +++ DIW+ G+ L LL
Sbjct: 167 LLHT-----TCGTPAYVAPEVI--------------NRKGYDGTKADIWSCGVVLFVLLA 207
Query: 355 GMLPFISDYELELFDKI 371
G LPF +E++ KI
Sbjct: 208 GYLPFHDSNLMEMYRKI 224
>YCL024w [T] KOG0583 Serine/threonine protein kinase
Length = 1037
Score = 108 bits (271), Expect = 3e-23
Identities = 91/315 (28%), Positives = 140/315 (43%), Gaps = 49/315 (15%)
Query: 112 LNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIED 171
+ +++ E LG G GKV+LA+ T A+K+++ K FN+ N + +
Sbjct: 18 IGPWKLGETLGFGSTGKVQLAQHERTGHRTAVKVIS---KSIFNN---NGNHSNDDSVLP 71
Query: 172 EKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKARGP 231
I+REI IMK H +V+ L +V + + +YL+LEY KGE+ D GP
Sbjct: 72 YNIEREIVIMKLLSHPNVLSLYDVWET--NNNLYLILEYAEKGELFNLLVD------HGP 123
Query: 232 PLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXXXXXXXX 291
L + FR +++G+ Y H GI+HRD+KP NLLL +KI+DFG+
Sbjct: 124 --LPEREAINCFRQIIIGISYCHALGIVHRDLKPENLLLDSFYNIKIADFGMAALQTDAD 181
Query: 292 XXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGITLHC 351
+ G+P + APEI S P F +D+W+ G+ L
Sbjct: 182 LLET--------SCGSPHYAAPEIV--------------SGLPYEGFASDVWSCGVILFA 219
Query: 352 LLFGMLPFISDYELELFDKIVNEPLVFEPYQKIEQCQVSQVECKEEYEEAQXXXXXXXXX 411
LL G LPF + + V + L+ K+++ Q E +AQ
Sbjct: 220 LLTGRLPFDEE------NGNVRDLLL-----KVQKGQFEMPNDTEISRDAQDLIGKILVV 268
Query: 412 XXXXRMAIQDAKKHP 426
R+ I+D HP
Sbjct: 269 DPRQRIKIRDILSHP 283
>At5g07070 [T] KOG0583 Serine/threonine protein kinase
Length = 456
Score = 108 bits (271), Expect = 3e-23
Identities = 79/257 (30%), Positives = 122/257 (46%), Gaps = 44/257 (17%)
Query: 115 YEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIEDEKI 174
YE+ LG G KV R T + VAIK++++ K + G+ ++I
Sbjct: 12 YEVGRLLGQGTFAKVYFGRSNHTNESVAIKMIDKDK-------------VMRVGLS-QQI 57
Query: 175 KREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKARGPPLL 234
KREI++M+ H +VV+L EV+ A +IY V+EYC GE+ A+G L
Sbjct: 58 KREISVMRIAKHPNVVELYEVM--ATKSRIYFVIEYCKGGEL-------FNKVAKGK--L 106
Query: 235 SFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXXXXXXXXXXX 294
+ F ++ +++ H +G+ HRDIKP NLLL ++ +K+SDFG+
Sbjct: 107 KEDVAWKYFYQLISAVDFCHSRGVYHRDIKPENLLLDDNDNLKVSDFGLSALADCKRQDG 166
Query: 295 XXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGITLHCLLF 354
T GTPA+ APE+ +++ DIW+ G+ L LL
Sbjct: 167 LLHT-----TCGTPAYVAPEVI--------------NRKGYEGTKADIWSCGVVLFVLLA 207
Query: 355 GMLPFISDYELELFDKI 371
G LPF +E++ KI
Sbjct: 208 GYLPFHDTNLMEMYRKI 224
>At3g23000 [T] KOG0583 Serine/threonine protein kinase
Length = 429
Score = 108 bits (271), Expect = 3e-23
Identities = 80/261 (30%), Positives = 117/261 (44%), Gaps = 43/261 (16%)
Query: 111 VLNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIE 170
+L YE+ LG G KV LAR + + +LVA+KI+ + K T +SG+E
Sbjct: 21 LLGKYELGRRLGSGSFAKVHLARSIESDELVAVKIIEKKK-------------TIESGME 67
Query: 171 DEKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKARG 230
I+ A+ + HH +++K+ EV+ A KIYLV+E S GE+ +K
Sbjct: 68 PRIIREIDAMRRLRHHPNILKIHEVM--ATKSKIYLVMELASGGELF--------SKVLR 117
Query: 231 PPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXXXXXXX 290
L R F+ + L + H G+ HRD+KP NLLL E G +K+SDFG+
Sbjct: 118 RGRLPESTARRYFQQLASALRFSHQDGVAHRDVKPQNLLLDEQGNLKVSDFGLSALPEHL 177
Query: 291 XXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGITLH 350
GTPA+ APE+ S+ D W+ G+ L
Sbjct: 178 QNGLLHT------ACGTPAYTAPEVI--------------SRRGYDGAKADAWSCGVILF 217
Query: 351 CLLFGMLPFISDYELELFDKI 371
LL G +PF ++ KI
Sbjct: 218 VLLVGDVPFDDSNIAAMYRKI 238
>7302570 [R] KOG0586 Serine/threonine protein kinase
Length = 702
Score = 108 bits (270), Expect = 4e-23
Identities = 84/270 (31%), Positives = 127/270 (46%), Gaps = 51/270 (18%)
Query: 106 ISKRKVLNT--YEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFK 163
IS K+L YE+ + +G G VKLA ++VTK VAIKI++ K N+++ N
Sbjct: 30 ISVDKLLRVGYYELEKTIGKGNFAVVKLATNIVTKTKVAIKIID---KTCLNEEYLN--- 83
Query: 164 TPQSGIEDEKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDV 223
K REIAI+K H H+ +L EV++ IYLV EY GEI D
Sbjct: 84 ---------KTFREIAILKSLRHPHITRLYEVMESQSM--IYLVTEYAPNGEIF----DH 128
Query: 224 IETKARGPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGV 283
+ R + +F ++ + Y H +G++HRD+K N+LL +D +K++DFG
Sbjct: 129 LVANGR----MKEPEAARVFTQLVSAVHYCHRRGVVHRDLKAENVLLDKDMNIKLADFGF 184
Query: 284 XXXXXXXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLD-PNSKEPIISFPTDI 342
G+P + APE+ + + D P S DI
Sbjct: 185 SNHYEEGATLKT--------WCGSPPYAAPEV------FQGLEYDGPKS---------DI 221
Query: 343 WAMGITLHCLLFGMLPFISDYELELFDKIV 372
W++G+ L+ L+ G LPF LEL ++V
Sbjct: 222 WSLGVVLYALVCGALPFDGKTILELKSRVV 251
>7299437 [R] KOG0586 Serine/threonine protein kinase
Length = 604
Score = 108 bits (270), Expect = 4e-23
Identities = 83/271 (30%), Positives = 130/271 (47%), Gaps = 47/271 (17%)
Query: 115 YEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIEDEKI 174
Y+II+ LG G KVKLA L T + VAIK+++ KT + I +K+
Sbjct: 63 YKIIKTLGKGNFAKVKLAIHLPTGREVAIKLID---------------KTALNTIARQKL 107
Query: 175 KREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKARGPPLL 234
RE+ IMKK +H ++V+L++V++ R +YLV+EY S GE+ + + R +
Sbjct: 108 YREVNIMKKLNHPNIVRLLQVIES--ERTLYLVMEYVSGGELF----NYLVKNGR----M 157
Query: 235 SFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXXXXXXXXXXX 294
+ R +FR ++ +EY H + I+HRD+K NLLL + +KI+DFG
Sbjct: 158 RERDARVLFRQLVSAIEYCHSKSIVHRDLKAENLLLDQQMKLKIADFGFSTTFEPKAPLE 217
Query: 295 XXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGITLHCLLF 354
G+P + APE+ KK+ D W++G+ L+ L+
Sbjct: 218 TF--------CGSPPYAAPELF----RGKKYS----------GPEVDSWSLGVVLYTLVS 255
Query: 355 GMLPFISDYELELFDKIVNEPLVFEPYQKIE 385
G LPF EL D+++ Y IE
Sbjct: 256 GSLPFDGTNLKELRDRVLRGKYRVPYYVSIE 286
>Hs8923922 [R] KOG0586 Serine/threonine protein kinase
Length = 795
Score = 107 bits (268), Expect = 7e-23
Identities = 78/261 (29%), Positives = 127/261 (47%), Gaps = 47/261 (18%)
Query: 112 LNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIED 171
+ Y + + +G G KVKLAR ++T + VA+KI++ KT +
Sbjct: 57 IGNYRLQKTIGKGNFAKVKLARHVLTGREVAVKIID---------------KTQLNPTSL 101
Query: 172 EKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKARGP 231
+K+ RE+ IMK +H ++VKL EV++ K+ +YLV+EY S GE+ D + R
Sbjct: 102 QKLFREVRIMKILNHPNIVKLFEVIETEKT--LYLVMEYASGGEVF----DYLVAHGR-- 153
Query: 232 PLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXXXXXXXX 291
+ + R FR ++ ++Y H + I+HRD+K NLLL D +KI+DFG
Sbjct: 154 --MKEKEARAKFRQIVSAVQYCHQKYIVHRDLKAENLLLDGDMNIKIADFGFSNEFTVGN 211
Query: 292 XXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGITLHC 351
G+P + APE+ KK+D D+W++G+ L+
Sbjct: 212 KLDTF--------CGSPPYAAPELF----QGKKYD----------GPEVDVWSLGVILYT 249
Query: 352 LLFGMLPFISDYELELFDKIV 372
L+ G LPF EL ++++
Sbjct: 250 LVSGSLPFDGQNLKELRERVL 270
>CE28643 [T] KOG0583 Serine/threonine protein kinase
Length = 564
Score = 107 bits (266), Expect = 1e-22
Identities = 102/405 (25%), Positives = 170/405 (41%), Gaps = 71/405 (17%)
Query: 115 YEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIEDEKI 174
Y + E LG G GKVK+ T+ VA+KI+NR K ++ + KI
Sbjct: 25 YILKETLGVGTFGKVKVGIHETTQYKVAVKILNRQKIKSLDVV--------------GKI 70
Query: 175 KREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKARGPPLL 234
+REI + H H+++L +V+ I++++E+ S GE+ D I R L
Sbjct: 71 RREIQNLSLFRHPHIIRLYQVISTPSD--IFMIMEHVSGGELF----DYIVKHGR----L 120
Query: 235 SFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXXXXXXXXXXX 294
R F+ ++ G++Y H ++HRD+KP NLLL E VKI+DFG+
Sbjct: 121 KTAEARRFFQQIISGVDYCHRHMVVHRDLKPENLLLDEQNNVKIADFGLSNIMTDGDFLR 180
Query: 295 XXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGITLHCLLF 354
+ G+P + APE+ S + D+W+ G+ L+ LL
Sbjct: 181 T--------SCGSPNYAAPEVI--------------SGKLYAGPEVDVWSCGVILYALLC 218
Query: 355 GMLPFISDYELELFDKIVNEPLVFEPYQKIEQCQVSQVE---CKEEYEEAQXXXXXXXXX 411
G LPF ++ LF KI + VF +E+ V+ + C + +
Sbjct: 219 GTLPFDDEHVPSLFRKIKSG--VFPTPDFLERPIVNLLHHMLCVDPMK------------ 264
Query: 412 XXXXRMAIQDAKKHPWVCWDFNHNDYMSDQEKSLKLIEQSNFHRSPSEQVEQICISEHEV 471
R I+D H W D + + E +++ + ++ ++E EV
Sbjct: 265 ----RATIKDVIAHEWFQKDLPNYLFPPINESEASIVDIEAVRE--VTEFQRYHVAEEEV 318
Query: 472 DTAVGGIG--HKIKNAVGKFLPSTKSNDESNTNSVNEFNDSGNNK 514
+A+ G H + A + + + DE+ S+ EF NK
Sbjct: 319 TSALLGDDPHHHLSIAYNLIVDNKRIADETAKLSIEEFYQVTPNK 363
>Hs21361133 [R] KOG0586 Serine/threonine protein kinase
Length = 752
Score = 106 bits (265), Expect = 2e-22
Identities = 80/276 (28%), Positives = 131/276 (46%), Gaps = 54/276 (19%)
Query: 112 LNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIED 171
+ Y +++ +G G KVKLAR ++T + VAIKI++ KT +
Sbjct: 53 IGNYRLLKTIGKGNFAKVKLARHILTGREVAIKIID---------------KTQLNPTSL 97
Query: 172 EKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEI---KWCPGDVIETKA 228
+K+ RE+ IMK +H ++VKL EV++ K+ +YL++EY S GE+ G + E +A
Sbjct: 98 QKLFREVRIMKILNHPNIVKLFEVIETEKT--LYLIMEYASGGEVFDYLVAHGKMKEKEA 155
Query: 229 RGP------------PLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIV 276
R +SF +F ++ ++Y H + I+HRD+K NLLL D +
Sbjct: 156 RSKFRQGCQAGQTIKVQVSFDLLSLMFTFIVSAVQYCHQKRIVHRDLKAENLLLDADMNI 215
Query: 277 KISDFGVXXXXXXXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPII 336
KI+DFG G+P + APE+ KK+D
Sbjct: 216 KIADFGFSNEFTVGGKLDTF--------CGSPPYAAPELF----QGKKYD---------- 253
Query: 337 SFPTDIWAMGITLHCLLFGMLPFISDYELELFDKIV 372
D+W++G+ L+ L+ G LPF EL ++++
Sbjct: 254 GPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVL 289
>7290249 [R] KOG0586 Serine/threonine protein kinase
Length = 1398
Score = 106 bits (264), Expect = 2e-22
Identities = 89/315 (28%), Positives = 136/315 (42%), Gaps = 62/315 (19%)
Query: 115 YEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIEDEKI 174
Y+I +G G VKLAR +TK VAIKI+++ + N +K+
Sbjct: 141 YDIERTIGKGNFAVVKLARHRITKNEVAIKIIDKSQLDQTNL---------------QKV 185
Query: 175 KREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKARGPPLL 234
RE+ IMK+ H H++KL +V++ IY+V EY S+GEI D I R +
Sbjct: 186 YREVEIMKRLKHPHIIKLYQVMET--KNMIYIVSEYASQGEIF----DYIAKYGR----M 235
Query: 235 SFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXXXXXXXXXXX 294
S R F ++ +EY H +GI+HRD+K NLLL + +KI+DFG
Sbjct: 236 SESAARFKFWQIISAVEYCHKKGIVHRDLKAENLLLDLNMNIKIADFG--------FSNH 287
Query: 295 XXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGITLHCLLF 354
A G+P + APE+ F+ + I DIW++G+ L+ L+
Sbjct: 288 FKPGELLATWCGSPPYAAPEV---------FEGKQYTGPEI-----DIWSLGVVLYVLVC 333
Query: 355 GMLPFISDYELELFDKIVNEPLVFEPYQKIEQCQVSQVECKEEYEEAQXXXXXXXXXXXX 414
G LPF L D++++ P+ +C +
Sbjct: 334 GALPFDGSTLQSLRDRVLSGRFRI-PFFMSSEC--------------EHLIRRMLVLEPT 378
Query: 415 XRMAIQDAKKHPWVC 429
R I K+H W+C
Sbjct: 379 RRYTIDQIKRHRWMC 393
>7302464 [R] KOG0586 Serine/threonine protein kinase
Length = 739
Score = 105 bits (263), Expect = 3e-22
Identities = 78/261 (29%), Positives = 127/261 (47%), Gaps = 47/261 (18%)
Query: 112 LNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIED 171
+ Y++I+ +G G KVKLA+ L T + VAIKI++ KT +
Sbjct: 148 IGKYKLIKTIGKGNFAKVKLAKHLPTGKEVAIKIID---------------KTQLNPGSL 192
Query: 172 EKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKARGP 231
+K+ RE+ IMK H ++VKL +V++ K+ +YL++EY S GE+ D + R
Sbjct: 193 QKLFREVRIMKMLDHPNIVKLFQVIETEKT--LYLIMEYASGGEVF----DYLVLHGR-- 244
Query: 232 PLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXXXXXXXX 291
+ + R FR ++ ++Y H + IIHRD+K NLLL + +KI+DFG
Sbjct: 245 --MKEKEARVKFRQIVSAVQYCHQKRIIHRDLKAENLLLDSELNIKIADFGFSNEFTPGS 302
Query: 292 XXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGITLHC 351
G+P + APE+ KK+D D+W++G+ L+
Sbjct: 303 KLDTF--------CGSPPYAAPELF----QGKKYD----------GPEVDVWSLGVILYT 340
Query: 352 LLFGMLPFISDYELELFDKIV 372
L+ G LPF EL ++++
Sbjct: 341 LVSGSLPFDGSTLRELRERVL 361
>At1g48260 [T] KOG0583 Serine/threonine protein kinase
Length = 432
Score = 105 bits (262), Expect = 4e-22
Identities = 78/245 (31%), Positives = 117/245 (46%), Gaps = 43/245 (17%)
Query: 115 YEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIEDEKI 174
YE+ LG G KVK A D +T + AIKI+ + N F +I
Sbjct: 11 YELGRTLGEGNSAKVKFAIDTLTGESFAIKIIEKSCITRLNVSF--------------QI 56
Query: 175 KREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKARGPPLL 234
KREI +K H ++V+L EVL A KIY+VLE + G++ D I +K + L
Sbjct: 57 KREIRTLKVLKHPNIVRLHEVL--ASKTKIYMVLECVTGGDLF----DRIVSKGK----L 106
Query: 235 SFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXXXXXXXXXXX 294
S + R++F+ ++ G+ Y H +G+ HRD+K N+LL G +KI+DFG+
Sbjct: 107 SETQGRKMFQQLIDGVSYCHNKGVFHRDLKLENVLLDAKGHIKITDFGLSALSQHYREDG 166
Query: 295 XXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGITLHCLLF 354
T G+P + APE+ + E +DIW+ G+ L+ +L
Sbjct: 167 LLHT-----TCGSPNYVAPEVL--------------ANEGYDGAASDIWSCGVILYVILT 207
Query: 355 GMLPF 359
G LPF
Sbjct: 208 GCLPF 212
>At3g17510 [T] KOG0583 Serine/threonine protein kinase
Length = 446
Score = 104 bits (260), Expect = 6e-22
Identities = 78/260 (30%), Positives = 120/260 (46%), Gaps = 43/260 (16%)
Query: 112 LNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIED 171
L YE+ LG G GKVK A+D V+ A+KI+++ + N
Sbjct: 17 LGKYELGRTLGEGNFGKVKFAKDTVSGHSFAVKIIDKSRIADLNFSL------------- 63
Query: 172 EKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKARGP 231
+IKREI +K H H+V+L EVL A KI +V+E + GE+ D I + +
Sbjct: 64 -QIKREIRTLKMLKHPHIVRLHEVL--ASKTKINMVMELVTGGELF----DRIVSNGK-- 114
Query: 232 PLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXXXXXXXX 291
L+ R++F+ ++ G+ Y H +G+ HRD+K N+LL G +KI+DFG+
Sbjct: 115 --LTETDGRKMFQQLIDGISYCHSKGVFHRDLKLENVLLDAKGHIKITDFGLSALPQHFR 172
Query: 292 XXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGITLHC 351
T G+P + APE+ + +DIW+ G+ L+
Sbjct: 173 DDGLLHT-----TCGSPNYVAPEVL--------------ANRGYDGAASDIWSCGVILYV 213
Query: 352 LLFGMLPFISDYELELFDKI 371
+L G LPF L+ KI
Sbjct: 214 ILTGCLPFDDRNLAVLYQKI 233
>Hs4502803 [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 476
Score = 104 bits (259), Expect = 8e-22
Identities = 84/245 (34%), Positives = 117/245 (47%), Gaps = 45/245 (18%)
Query: 115 YEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIEDEKI 174
+++++ LG G +G+V+LA + VT++ VA+KIV+ KR + E I
Sbjct: 9 WDLVQTLGEGAYGEVQLAVNRVTEEAVAVKIVDM--KRAVDCP--------------ENI 52
Query: 175 KREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKARGPPLL 234
K+EI I K +HE+VVK + + YL LEYCS GE+ D IE G P
Sbjct: 53 KKEICINKMLNHENVVKFYGHRREGNIQ--YLFLEYCSGGELF----DRIEPDI-GMPEP 105
Query: 235 SFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXXXXXXXXXXX 294
QR F ++ G+ YLH GI HRDIKP NLLL E +KISDFG+
Sbjct: 106 DAQR---FFHQLMAGVVYLHGIGITHRDIKPENLLLDERDNLKISDFGLATVFRYNNRER 162
Query: 295 XXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGITLHCLLF 354
K GT + APE+ + + P D+W+ GI L +L
Sbjct: 163 LLN-----KMCGTLPYVAPELL--------------KRREFHAEPVDVWSCGIVLTAMLA 203
Query: 355 GMLPF 359
G LP+
Sbjct: 204 GELPW 208
>At5g01820 [T] KOG0583 Serine/threonine protein kinase
Length = 442
Score = 104 bits (259), Expect = 8e-22
Identities = 85/274 (31%), Positives = 124/274 (45%), Gaps = 49/274 (17%)
Query: 101 LEYDPISKR-KVLNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFS 159
+E+ P ++R ++ YE+ + +G G KV R T Q VAIK+V++ +
Sbjct: 7 VEFPPENRRGQLFGKYEVGKLVGCGAFAKVYHGRSTATGQSVAIKVVSKQRL-------- 58
Query: 160 NRFKTPQSGIEDEKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEI--K 217
Q G + I+REIAIM + H +V+L EVL A KI+ V+E+ GE+ K
Sbjct: 59 ------QKGGLNGNIQREIAIMHRLRHPSIVRLFEVL--ATKSKIFFVMEFAKGGELFAK 110
Query: 218 WCPGDVIETKARGPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVK 277
G E +R F+ ++ + Y H +GI HRD+KP NLLL E +K
Sbjct: 111 VSKGRFCE-----------DLSRRYFQQLISAVGYCHSRGIFHRDLKPENLLLDEKLDLK 159
Query: 278 ISDFGVXXXXXXXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIIS 337
ISDFG+ GTPA+ APE+ +K+
Sbjct: 160 ISDFGLSALTDQIRPDGLLHT-----LCGTPAYVAPEVL--------------AKKGYDG 200
Query: 338 FPTDIWAMGITLHCLLFGMLPFISDYELELFDKI 371
DIW+ GI L L G LPF + ++ KI
Sbjct: 201 AKIDIWSCGIILFVLNAGYLPFNDHNLMVMYRKI 234
>YLR096w [T] KOG0583 Serine/threonine protein kinase
Length = 1147
Score = 103 bits (258), Expect = 1e-21
Identities = 80/289 (27%), Positives = 125/289 (42%), Gaps = 44/289 (15%)
Query: 109 RKVLNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSG 168
R+ L +E +E +G G GKVKL + TK++ IKIVNR K + + S +S
Sbjct: 93 RRSLGDWEFLETVGAGSMGKVKLVKHRQTKEICVIKIVNRASKAYLHKQHSLPSPKNESE 152
Query: 169 I------------EDEKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEI 216
I D++ RE ++ + +H H+ +L E+ S Y++ EY S G++
Sbjct: 153 ILERQKRLEKEIARDKRTVREASLGQILYHPHICRLFEMC--TMSNHFYMLFEYVSGGQL 210
Query: 217 KWCPGDVIETKARGPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIV 276
D I L R+ RG+ L+YLH I+HRD+K N+++S G +
Sbjct: 211 L----DYIIQHGS----LKEHHARKFARGIASALQYLHANNIVHRDLKIENIMISSSGEI 262
Query: 277 KISDFGVXXXXXXXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPII 336
KI DFG+ G+ F APE+ +P
Sbjct: 263 KIIDFGLSNIFDYRKQLHTF--------CGSLYFAAPELL--------------KAQPYT 300
Query: 337 SFPTDIWAMGITLHCLLFGMLPFISDYELELFDKIVNEPLVFEPYQKIE 385
DIW+ GI L+ L+ G +PF + L +KI + + + IE
Sbjct: 301 GPEVDIWSFGIVLYVLVCGKVPFDDENSSILHEKIKKGKVDYPSHLSIE 349
>Hs14770402 [R] KOG0586 Serine/threonine protein kinase
Length = 926
Score = 103 bits (257), Expect = 1e-21
Identities = 85/274 (31%), Positives = 121/274 (44%), Gaps = 48/274 (17%)
Query: 115 YEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIEDEKI 174
Y+I LG G VKL R +TK VAIKI++ K+ + EKI
Sbjct: 20 YDIEGTLGKGNFAVVKLGRHRITKTEVAIKIID---------------KSQLDAVNLEKI 64
Query: 175 KREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKARGPPLL 234
RE+ IMK H H++KL +V++ +YLV EY GEI D + R L
Sbjct: 65 YREVQIMKMLDHPHIIKLYQVMETKSM--LYLVTEYAKNGEIF----DYLANHGR----L 114
Query: 235 SFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXXXXXXXXXXX 294
+ R F +L ++Y H + I+HRD+K NLLL + +KI+DFG
Sbjct: 115 NESEARRKFWQILSAVDYCHGRKIVHRDLKAENLLLDNNMNIKIADFG--------FGNF 166
Query: 295 XXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGITLHCLLF 354
A G+P + APE+ F+ + DIW+MG+ L+ L+
Sbjct: 167 FKSGELLATWCGSPPYAAPEV---------FEGQQYEGPQL-----DIWSMGVVLYVLVC 212
Query: 355 GMLPFISDYELELFDKIVNEPLVFEPYQKIEQCQ 388
G LPF L + + V E PY E C+
Sbjct: 213 GALPF-DGPTLPILRQRVLEGRFRIPYFMSEDCE 245
>SPCC18B5.11c [D] KOG0615 Serine/threonine protein kinase Chk2 and related
proteins
Length = 460
Score = 103 bits (256), Expect = 2e-21
Identities = 97/394 (24%), Positives = 161/394 (40%), Gaps = 53/394 (13%)
Query: 65 LNHPLHQNHIRTVL--GSHLNSGQRITYGPVKETNTVSLEYDPISKRKVLNT----YEII 118
LN + RT+L G + G + + V +++ S++ ++ + YEII
Sbjct: 111 LNFERLAKNSRTILSNGDEIRIGLGVPKDEISFLCQVPVKHSRDSQKNMIKSENSHYEII 170
Query: 119 EELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIEDEKIKREI 178
LG G VKLA ++ + + AIKI+N+ K T E +REI
Sbjct: 171 RTLGSGTFAVVKLAVEVNSGKWYAIKIINKRKI----------LLTSSEKRATEMFQREI 220
Query: 179 AIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKARGPPLLSFQR 238
I+K HH VV+ E+ ++ ++++V+EY G++ D + + Q
Sbjct: 221 DILKSLHHPGVVQCHEIFEN--DDELFIVMEYVEGGDLM----DFLIANGS----IDEQD 270
Query: 239 TREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXXXXXXXXXXXXXXX 298
+ + + +L L +LH QG+ HRDIKP N+L++ D +KISDFG+
Sbjct: 271 CKPLLKQLLETLLHLHKQGVTHRDIKPENILITNDFHLKISDFGLAKVIHGTGTFLETF- 329
Query: 299 XXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGITLHCLLFGMLP 358
GT + APE+ K +LD + + DIW++G L+ +L +P
Sbjct: 330 ------CGTMGYLAPEVL----KSKNVNLDGGYDDKV-----DIWSLGCVLYVMLTASIP 374
Query: 359 FISDYELELFDKIVNEPLVFEPYQKIEQCQVSQVECKEEYEEAQXXXXXXXXXXXXXRMA 418
F S + + + I EP + E EE R++
Sbjct: 375 FASSSQAKCIELISKGAYPIEPLLE-----------NEISEEGIDLINRMLEINPEKRIS 423
Query: 419 IQDAKKHPWVCWDFNHNDYMSDQEKSLKLIEQSN 452
+A +HPW H + EQ N
Sbjct: 424 ESEALQHPWFYTVSTHEHRTPPSSSEHEATEQLN 457
>Hs14670383 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 370
Score = 103 bits (256), Expect = 2e-21
Identities = 85/329 (25%), Positives = 140/329 (41%), Gaps = 59/329 (17%)
Query: 104 DPISKRKVLNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFK 163
+P ++KV + Y+I EELG GQ VK R+ T A K + + + R
Sbjct: 12 EPFKQQKVEDFYDIGEELGSGQFAIVKKCREKSTGLEYAAKFIKKRQSR----------- 60
Query: 164 TPQSGIEDEKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDV 223
+ G+ E+I+RE++I+++ H +V+ L +V ++ + L+LE S GE+ D
Sbjct: 61 ASRRGVSREEIEREVSILRQVLHHNVITLHDVYENRTD--VVLILELVSGGEL----FDF 114
Query: 224 IETKARGPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGI----VKIS 279
+ K LS + + +L G+ YLH + I H D+KP N++L + I +K+
Sbjct: 115 LAQKES----LSEEEATSFIKQILDGVNYLHTKKIAHFDLKPENIMLLDKNIPIPHIKLI 170
Query: 280 DFGVXXXXXXXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFP 339
DFG+ GTP F APEI E +
Sbjct: 171 DFGL--------AHEIEDGVEFKNIFGTPEFVAPEIVNYEP---------------LGLE 207
Query: 340 TDIWAMGITLHCLLFGMLPFISDYELELFDKIVNEPLVFEPYQKIEQCQVSQVECKEEYE 399
D+W++G+ + LL G PF+ D + E I F+ + + E
Sbjct: 208 ADMWSIGVITYILLSGASPFLGDTKQETLANITAVSYDFD-----------EEFFSQTSE 256
Query: 400 EAQXXXXXXXXXXXXXRMAIQDAKKHPWV 428
A+ R+ IQ+A +HPW+
Sbjct: 257 LAKDFIRKLLVKETRKRLTIQEALRHPWI 285
>YKL101w [D] KOG0588 Serine/threonine protein kinase
Length = 1518
Score = 102 bits (255), Expect = 2e-21
Identities = 88/321 (27%), Positives = 145/321 (44%), Gaps = 56/321 (17%)
Query: 73 HIRTVLGSHLNSGQRITYGPVKETNTVSLEYDPISKRKVLNTYEIIEELGHGQHGKVKLA 132
H+ V+ S ++ +R++ T +V+ + R + +++ + LG G G+V+LA
Sbjct: 41 HLERVVQSVNDATKRLSQPD--STVSVATKSSKRKSRDTVGPWKLGKTLGKGSSGRVRLA 98
Query: 133 RDLVTKQLVAIKIVNRHK---------------------KRTFNDKFSNRFKTPQSGIED 171
+++ T QL AIKIV + K + ++R + S
Sbjct: 99 KNMETGQLAAIKIVPKKKAFVHCSNNGTVPNSYSSSMVTSNVSSPSIASREHSNHSQTNP 158
Query: 172 EKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKARGP 231
I+REI IMK H +V+ L EV ++ ++YLVLEY GE+ D + +K + P
Sbjct: 159 YGIEREIVIMKLISHTNVMALFEVWEN--KSELYLVLEYVDGGEL----FDYLVSKGKLP 212
Query: 232 PLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLL-SEDGIVKISDFGVXXXXXXX 290
+ F+ ++ G+ Y H I HRD+KP NLLL ++ +KI+DFG+
Sbjct: 213 E----REAIHYFKQIVEGVSYCHSFNICHRDLKPENLLLDKKNRRIKIADFGMAALELPN 268
Query: 291 XXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGITLH 350
+ G+P + +PEI + P P+D+W+ GI L
Sbjct: 269 KLLKT--------SCGSPHYASPEIVM--------------GRPYHGGPSDVWSCGIVLF 306
Query: 351 CLLFGMLPFISDYELELFDKI 371
LL G LPF D +L K+
Sbjct: 307 ALLTGHLPFNDDNIKKLLLKV 327
>At5g57630 [T] KOG0583 Serine/threonine protein kinase
Length = 412
Score = 102 bits (255), Expect = 2e-21
Identities = 75/271 (27%), Positives = 120/271 (43%), Gaps = 47/271 (17%)
Query: 110 KVLNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGI 169
K + YEI +G G KVKL D VA+KI+++ Q G+
Sbjct: 7 KKIGKYEIGRTIGEGNFAKVKLGYDTTNGTYVAVKIIDKAL-------------VIQKGL 53
Query: 170 EDEKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKAR 229
E + +KREI MK +H ++V++ EV+ KI +V+EY S G++ +
Sbjct: 54 ESQ-VKREIRTMKLLNHPNIVQIHEVI--GTKTKICIVMEYVSGGQL---------SDRL 101
Query: 230 GPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXXXXXX 289
G + R++F+ ++ ++Y H +G+ HRD+KP NLLL G +K+SDFG+
Sbjct: 102 GRQKMKESDARKLFQQLIDAVDYCHNRGVYHRDLKPQNLLLDSKGNLKVSDFGL------ 155
Query: 290 XXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGITL 349
+ G+P + APE+ + + D+W+ G+ L
Sbjct: 156 --SAVPKSGDMLSTACGSPCYIAPELIM--------------NKGYSGAAVDVWSCGVIL 199
Query: 350 HCLLFGMLPFISDYELELFDKIVNEPLVFEP 380
LL G PF L+ KI+ F P
Sbjct: 200 FELLAGYPPFDDHTLPVLYKKILRADYTFPP 230
>YDR477w [T] KOG0583 Serine/threonine protein kinase
Length = 633
Score = 102 bits (254), Expect = 3e-21
Identities = 79/263 (30%), Positives = 122/263 (46%), Gaps = 49/263 (18%)
Query: 112 LNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIED 171
+ Y+I++ LG G GKVKLA T Q VA+KI+N+ K+ G
Sbjct: 52 IGNYQIVKTLGEGSFGKVKLAYHTTTGQKVALKIINKKVLA----------KSDMQG--- 98
Query: 172 EKIKREIAIMKKCHHEHVVKLIEVLDDAKSR-KIYLVLEYCSKGEIKWCPGDVIETKARG 230
+I+REI+ ++ H H++KL +V+ KS+ +I +V+EY D I + +
Sbjct: 99 -RIEREISYLRLLRHPHIIKLYDVI---KSKDEIIMVIEYAGNELF-----DYIVQRDK- 148
Query: 231 PPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXXXXXXX 290
+S Q R F+ ++ +EY H I+HRD+KP NLLL E VKI+DFG+
Sbjct: 149 ---MSEQEARRFFQQIISAVEYCHRHKIVHRDLKPENLLLDEHLNVKIADFGLSNIMTDG 205
Query: 291 XXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGITLH 350
+ G+P + APE+ S + D+W+ G+ L+
Sbjct: 206 NFLKT--------SCGSPNYAAPEVI--------------SGKLYAGPEVDVWSCGVILY 243
Query: 351 CLLFGMLPFISDYELELFDKIVN 373
+L LPF + LF I N
Sbjct: 244 VMLCRRLPFDDESIPVLFKNISN 266
>At2g38490 [T] KOG0583 Serine/threonine protein kinase
Length = 431
Score = 102 bits (254), Expect = 3e-21
Identities = 93/329 (28%), Positives = 138/329 (41%), Gaps = 65/329 (19%)
Query: 107 SKRKVLNTYEIIEELGHGQHGKVKLARDLVTK-QLVAIKIVNRHKKRTFNDKFSNRFKTP 165
+K + Y++ + LG G KV A DL + VAIK+V +K+ D +
Sbjct: 20 NKSALFGKYDLGKLLGSGAFAKVYQAEDLQNGGESVAIKVV---QKKRLKDGLTAH---- 72
Query: 166 QSGIEDEKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIE 225
+KREI++M++ H H+V L EVL A KIY V+E GE+
Sbjct: 73 --------VKREISVMRRLRHPHIVLLSEVL--ATKTKIYFVMELAKGGELF-----SRV 117
Query: 226 TKARGPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXX 285
T R LS R+ FR ++ + Y H +G+ HRD+KP NLLL E+ +K+SDFG+
Sbjct: 118 TSNRFTESLS----RKYFRQLISAVRYCHARGVFHRDLKPENLLLDENRDLKVSDFGLSA 173
Query: 286 XXXXXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAM 345
GTPA+ APE+ L K+ DIW+
Sbjct: 174 MKEQIHPDGMLHT-----LCGTPAYVAPELLL--------------KKGYDGSKADIWSC 214
Query: 346 GITLHCLLFGMLPFISDYELELFDKIVNEPLVFEPYQKIEQCQVSQVECKEEYEEAQXXX 405
G+ L L G LPF +P + Y+KI + Q + + +
Sbjct: 215 GVVLFLLNAGYLPF-------------RDPNIMGLYRKIHKAQYKLPDWTS--SDLRKLL 259
Query: 406 XXXXXXXXXXRMAIQDAKKHPWVCWDFNH 434
R+ +++ K PW FNH
Sbjct: 260 RRLLEPNPELRITVEEILKDPW----FNH 284
>7299438 [R] KOG0586 Serine/threonine protein kinase
Length = 705
Score = 102 bits (254), Expect = 3e-21
Identities = 80/289 (27%), Positives = 133/289 (45%), Gaps = 48/289 (16%)
Query: 84 SGQRITYGPVKETNTVSLEYDPISKRKVLNTYEIIEELGHGQHGKVKLARDLVTKQLVAI 143
+GQ + G NT S ++ Y+II+ LG G KVKLA + T + VAI
Sbjct: 68 AGQDLGDGACSSKNTDS-KFQSYVNGNGNGVYKIIKTLGKGNFAKVKLAIHVPTGREVAI 126
Query: 144 KIVNRHKKRTFNDKFSNRFKTPQSGIEDEKIKREIAIMKKCHHEHVVKLIEVLDDAKSRK 203
K+++ KT + +K+ RE+ IMK +H ++V+L +V++ R
Sbjct: 127 KVID---------------KTQLNTSARQKLYREVKIMKLLNHPNIVRLFQVIES--ERT 169
Query: 204 IYLVLEYCSKGEIKWCPGDVIETKARGPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDI 263
+YLV+EY S+GE+ D + R + + R IFR ++ ++Y H + ++HRD+
Sbjct: 170 LYLVMEYASRGELF----DHLVKNGR----MRERDARVIFRQLVSAIQYCHSKFVVHRDL 221
Query: 264 KPANLLLSEDGIVKISDFGVXXXXXXXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIK 323
K NLLL + +KI+DFG G+P + APE+ +
Sbjct: 222 KAENLLLDQHMNIKIADFGFGNTFDPNAQLETF--------CGSPPYAAPELFM------ 267
Query: 324 KFDLDPNSKEPIISFPTDIWAMGITLHCLLFGMLPFISDYELELFDKIV 372
D W++G+ L+ L+ G LPF EL ++++
Sbjct: 268 --------GRKYAGPEVDAWSLGVVLYTLVSGSLPFDGGTLKELRERVL 308
>Hs5453966 [T] KOG0583 Serine/threonine protein kinase
Length = 552
Score = 102 bits (253), Expect = 4e-21
Identities = 78/263 (29%), Positives = 117/263 (43%), Gaps = 46/263 (17%)
Query: 109 RKVLNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSG 168
R + Y + + LG G GKVK+ +T VA+KI+NR K R+ +
Sbjct: 10 RVKIGHYVLGDTLGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVV----------- 58
Query: 169 IEDEKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKA 228
KIKREI +K H H++KL +V+ ++V+EY S GE+ D I
Sbjct: 59 ---GKIKREIQNLKLFRHPHIIKLYQVISTPTD--FFMVMEYVSGGELF----DYICKHG 109
Query: 229 RGPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXXXXX 288
R + R +F+ +L ++Y H ++HRD+KP N+LL KI+DFG+
Sbjct: 110 R----VEEMEARRLFQQILSAVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMS 165
Query: 289 XXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGIT 348
+ G+P + APE+ S DIW+ G+
Sbjct: 166 DGEFLRT--------SCGSPNYTAPEVI--------------SGRLYAGPEVDIWSCGVI 203
Query: 349 LHCLLFGMLPFISDYELELFDKI 371
L+ LL G LPF ++ LF KI
Sbjct: 204 LYALLCGTLPFDDEHVPTLFKKI 226
>Hs20479818 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 514
Score = 101 bits (251), Expect = 7e-21
Identities = 81/281 (28%), Positives = 123/281 (42%), Gaps = 57/281 (20%)
Query: 121 LGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIEDEKIKREIAI 180
LG G G V A D T+ AIK VN+ K + K ++RE+ I
Sbjct: 122 LGKGSFGIVIEATDKETETKWAIKKVNKEKAGSSAVKL---------------LEREVNI 166
Query: 181 MKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKARGPPLLSFQRTR 240
+K HEH++ L +V + K K+YLV+E C GE+K ++++ K S TR
Sbjct: 167 LKSVKHEHIIHLEQVFETPK--KMYLVMELCEDGELK----EILDRKGH----FSENETR 216
Query: 241 EIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGI---------VKISDFGVXXXXXXXX 291
I + + + YLH I+HRD+K N+++ I +K++DFG+
Sbjct: 217 WIIQSLASAIAYLHNNDIVHRDLKLENIMVKSSLIDDNNEINLNIKVTDFGLAVKKQSRS 276
Query: 292 XXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGITLHC 351
T GTP + APE+ D S DIW++G+ ++
Sbjct: 277 EAMLQA------TCGTPIYMAPEVISAHD---------------YSQQCDIWSIGVVMYM 315
Query: 352 LLFGMLPFISDYELELFDKIVNEPLVFE--PYQKIEQCQVS 390
LL G PF++ E +LF+ I L FE + I C S
Sbjct: 316 LLRGEPPFLASSEEKLFELIRKGELHFENAVWNSISDCAKS 356
>7304283 [Z] KOG0613 Projectin/twitchin and related proteins
Length = 7175
Score = 101 bits (251), Expect = 7e-21
Identities = 92/370 (24%), Positives = 155/370 (41%), Gaps = 77/370 (20%)
Query: 91 GPVKETNT----VSLEYDP----ISKRKVLNTYEIIEELGHGQHGKVKLARDLVTKQLVA 142
GPVK+ ++ + ++ P IS++ V + Y+I+EE+G G G
Sbjct: 6106 GPVKDYDSYVFDIYSKFVPQPVEISQQSVYDRYDILEEIGTGAFG--------------- 6150
Query: 143 IKIVNRHKKRTFNDKFSNRFKTPQSGIEDEKIKREIAIMKKCHHEHVVKLIEVLDDAKSR 202
+V+R ++R+ + F+ +F +E + I+REI IM + HH+ ++ L + +D
Sbjct: 6151 --VVHRCRERSTGNIFAAKFIPVSHSVEKDLIRREIDIMNQLHHQKLINLHDAFED--DD 6206
Query: 203 KIYLVLEYCSKGEIKWCPGDVIETKARGPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRD 262
++ L+LE+ S GE+ E +++ R + G+ ++H Q IIH D
Sbjct: 6207 EMILILEFLSGGEL-------FERITAEGYVMTEAEVINYMRQICEGIRHMHEQNIIHLD 6259
Query: 263 IKPANLLLS--EDGIVKISDFGVXXXXXXXXXXXXXXXXXXAKTAGTPAFFAPEICLVED 320
IKP N++ VK+ DFG+ T GT F APEI
Sbjct: 6260 IKPENIMCQTRSSTNVKLIDFGLATRLDPNEVVKI--------TTGTAEFAAPEIV---- 6307
Query: 321 TIKKFDLDPNSKEPIISFPTDIWAMGITLHCLLFGMLPFISDYELELFDKIVNEPLVFEP 380
++EP + F TD+WA G+ + LL G+ PF D +++ +
Sbjct: 6308 ----------NREP-VGFYTDMWATGVLSYVLLSGLSPFAGDNDVQTLKNV--------- 6347
Query: 381 YQKIEQCQVSQVECKEEYEEAQXXXXXXXXXXXXXRMAIQDAKKHPWVCWD-------FN 433
K K EEA+ RM + HPW+ D N
Sbjct: 6348 --KACDWDFDVESFKYISEEAKDFIRKLLVRNKEKRMTAHECLLHPWLTGDHSAMKQEIN 6405
Query: 434 HNDYMSDQEK 443
+ Y++ +EK
Sbjct: 6406 RDRYLAYREK 6415
>At5g08590 [T] KOG0583 Serine/threonine protein kinase
Length = 353
Score = 100 bits (250), Expect = 9e-21
Identities = 84/318 (26%), Positives = 135/318 (42%), Gaps = 61/318 (19%)
Query: 112 LNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIED 171
++ Y+++++LG G G +L R TK+LVA+K + R +K D
Sbjct: 1 MDKYDVVKDLGAGNFGVARLLRHKDTKELVAMKYIERGRK------------------ID 42
Query: 172 EKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKARGP 231
E + REI + H ++++ EV+ + +V+EY S GE+ D I T R
Sbjct: 43 ENVAREIINHRSLKHPNIIRFKEVI--LTPTHLAIVMEYASGGEL----FDRICTAGR-- 94
Query: 232 PLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLL--SEDGIVKISDFGVXXXXXX 289
S R F+ ++ G++Y H I HRD+K N LL S ++KI DFG
Sbjct: 95 --FSEAEARYFFQQLICGVDYCHSLQICHRDLKLENTLLDGSPAPLLKICDFG------- 145
Query: 290 XXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGITL 349
T GTPA+ APE+ S+ D+W+ G+TL
Sbjct: 146 -YSKSSILHSRPKSTVGTPAYIAPEVL--------------SRREYDGKHADVWSCGVTL 190
Query: 350 HCLLFGMLPFISDYELELFDKIVNEPLVFEPYQKIEQCQVSQVECKEEYEEAQXXXXXXX 409
+ +L G PF + + F K + + + Y+ + +SQ ECK
Sbjct: 191 YVMLVGAYPFEDPNDPKNFRKTIQRIMAVQ-YKIPDYVHISQ-ECKH-------LLSRIF 241
Query: 410 XXXXXXRMAIQDAKKHPW 427
R+ +++ K HPW
Sbjct: 242 VTNSAKRITLKEIKNHPW 259
>YDR122w [T] KOG0583 Serine/threonine protein kinase
Length = 1064
Score = 100 bits (249), Expect = 1e-20
Identities = 77/289 (26%), Positives = 125/289 (42%), Gaps = 44/289 (15%)
Query: 109 RKVLNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNR------HKKRTF------ND 156
RK L +E +E +G G GKVKLA+ T ++ A+KIVNR HK++ D
Sbjct: 114 RKSLGDWEFVETVGAGSMGKVKLAKHRYTNEVCAVKIVNRATKAFLHKEQMLPPPKNEQD 173
Query: 157 KFSNRFKTPQSGIEDEKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEI 216
+ K + D++ RE ++ + +H H+ +L E+ S Y++ EY S G++
Sbjct: 174 VLERQKKLEKEISRDKRTIREASLGQILYHPHICRLFEMC--TLSNHFYMLFEYVSGGQL 231
Query: 217 KWCPGDVIETKARGPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIV 276
D I + + R+ RG+ L YLH I+HRD+K N+++S+ +
Sbjct: 232 L----DYIIQHGS----IREHQARKFARGIASALIYLHANNIVHRDLKIENIMISDSSEI 283
Query: 277 KISDFGVXXXXXXXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPII 336
KI DFG+ G+ F APE+ P
Sbjct: 284 KIIDFGLSNIYDSRKQLHTF--------CGSLYFAAPELL--------------KANPYT 321
Query: 337 SFPTDIWAMGITLHCLLFGMLPFISDYELELFDKIVNEPLVFEPYQKIE 385
D+W+ G+ L L+ G +PF + L +KI + + + IE
Sbjct: 322 GPEVDVWSFGVVLFVLVCGKVPFDDENSSVLHEKIKQGKVEYPQHLSIE 370
>7299322 [R] KOG0611 Predicted serine/threonine protein kinase
Length = 434
Score = 100 bits (249), Expect = 1e-20
Identities = 73/245 (29%), Positives = 117/245 (46%), Gaps = 46/245 (18%)
Query: 115 YEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIEDEKI 174
++II++LG G +GKV+L + T Q VAIK + + K D +I
Sbjct: 82 FDIIKKLGQGTYGKVQLGINKETGQEVAIKTIKKCKIEAEADLV--------------RI 127
Query: 175 KREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKARGPPLL 234
+RE+ IM HH +++ + EV ++ + K+ LV+E+ + GE+ D + + +L
Sbjct: 128 RREVQIMSSVHHPNIIHIYEVFENRE--KMVLVMEFAAGGELY----DYLSERK----VL 177
Query: 235 SFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXXXXXXXXXXX 294
+ + R IFR V + Y H I HRD+K N+LL E G KI+DFG+
Sbjct: 178 TEEEARRIFRQVATAVYYCHKHKICHRDLKLENILLDEKGNAKIADFGLSNVFDDQRLLG 237
Query: 295 XXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGITLHCLLF 354
G+P + +PEI VE T P D W++G+ L+ L++
Sbjct: 238 TF--------CGSPLYASPEI--VEGT------------PYQGPEVDCWSLGVLLYTLVY 275
Query: 355 GMLPF 359
G +PF
Sbjct: 276 GSMPF 280
>CE07599 [T] KOG0576 Mitogen-activated protein kinase kinase kinase kinase
(MAP4K) germinal center kinase family
Length = 829
Score = 99.8 bits (247), Expect = 2e-20
Identities = 74/245 (30%), Positives = 113/245 (45%), Gaps = 46/245 (18%)
Query: 104 DPISKRKVLNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFK 163
D I + + YE+++ +G G +G+V ARD+ + L A+K+V K D F+
Sbjct: 4 DVIKRSNPADDYELLQRVGSGTYGEVYKARDIRSDSLAAVKVV----KLEAGDNFA---- 55
Query: 164 TPQSGIEDEKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDV 223
I++EI ++++C H +++ + ++++V+EYC G ++ D+
Sbjct: 56 ---------VIQQEIMVIRECSHPNIIAYFGSY--IRRDRLWIVMEYCGGGSLQ----DI 100
Query: 224 IETKARGPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGV 283
GP LS + + R L GL YLH G IHRDIK AN+LLS G VK++DFGV
Sbjct: 101 YHLT--GP--LSELQIAFVCRETLRGLNYLHNMGKIHRDIKGANILLSSSGDVKLADFGV 156
Query: 284 XXXXXXXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIW 343
GTP + APE+ VE K D+W
Sbjct: 157 AAQITATIGKRKSF-------IGTPYWMAPEVACVE------------KRGGYGMQCDVW 197
Query: 344 AMGIT 348
A GIT
Sbjct: 198 ATGIT 202
>At5g63650 [T] KOG0583 Serine/threonine protein kinase
Length = 360
Score = 99.4 bits (246), Expect = 3e-20
Identities = 89/360 (24%), Positives = 151/360 (41%), Gaps = 78/360 (21%)
Query: 112 LNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIED 171
++ YE++++LG G G +L R TK+LVA+K + R +K D
Sbjct: 1 MDKYEVVKDLGAGNFGVARLLRHKETKELVAMKYIERGRK------------------ID 42
Query: 172 EKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEI--KWC-PGDVIETKA 228
E + REI + H ++++ EV+ + +V+EY S GE+ + C G E +A
Sbjct: 43 ENVAREIINHRSLRHPNIIRFKEVI--LTPTHLAIVMEYASGGELFERICNAGRFSEAEA 100
Query: 229 RGPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLL--SEDGIVKISDFGVXXX 286
R F+ ++ G++Y H I HRD+K N LL S ++KI DFG
Sbjct: 101 -----------RYFFQQLICGVDYCHSLQICHRDLKLENTLLDGSPAPLLKICDFG---- 145
Query: 287 XXXXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMG 346
T GTPA+ APE+ S+ D+W+ G
Sbjct: 146 ----YSKSSLLHSRPKSTVGTPAYIAPEVL--------------SRREYDGKHADVWSCG 187
Query: 347 ITLHCLLFGMLPFISDYELELFDKIVNEPLVFEPYQKIEQCQVSQVECKEEYEEAQXXXX 406
+TL+ +L G PF + F K + + + Y+ + +SQ E +
Sbjct: 188 VTLYVMLVGGYPFEDPDDPRNFRKTIQRIMAVQ-YKIPDYVHISQ--------ECRHLLS 238
Query: 407 XXXXXXXXXRMAIQDAKKHPWVCWDFNHNDYMSDQEKSLKLIEQSNFHR--SPSEQVEQI 464
R+ +++ KKHPW Y+ + K L Q+ +++ +PS ++ +
Sbjct: 239 RIFVTNSAKRITLKEIKKHPW---------YLKNLPKELTEPAQAAYYKRETPSFSLQSV 289
>HsM4759010 [T] KOG0576 Mitogen-activated protein kinase kinase kinase kinase
(MAP4K) germinal center kinase family
Length = 819
Score = 98.2 bits (243), Expect = 6e-20
Identities = 74/248 (29%), Positives = 116/248 (45%), Gaps = 46/248 (18%)
Query: 101 LEYDPISKRKVLNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSN 160
+E +S + + +E+++ +G G +G V ARD VT +L A+KIV
Sbjct: 1 MELRDVSLQDPRDRFELLQRVGAGTYGDVYKARDTVTSELAAVKIVKL------------ 48
Query: 161 RFKTPQSGIEDEKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCP 220
G + +++EI I+++C H +VV I ++ ++++ +E+C G ++
Sbjct: 49 -----DPGDDISSLQQEITILRECRHPNVVAYIGSY--LRNDRLWICMEFCGGGSLQEI- 100
Query: 221 GDVIETKARGPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISD 280
A GP L ++ + R L GL +LH QG IHRDIK ANLLL+ G VK++D
Sbjct: 101 -----YHATGP--LEERQIAYVCRERLKGLHHLHSQGKIHRDIKGANLLLTLQGDVKLAD 153
Query: 281 FGVXXXXXXXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPT 340
FGV GTP + APE+ VE +L
Sbjct: 154 FGVSGELTASVAKRRSF-------IGTPYWMAPEVAAVERKGGYNEL------------C 194
Query: 341 DIWAMGIT 348
D+WA+GIT
Sbjct: 195 DVWALGIT 202
>Hs22035600 [T] KOG0576 Mitogen-activated protein kinase kinase kinase kinase
(MAP4K) germinal center kinase family
Length = 820
Score = 98.2 bits (243), Expect = 6e-20
Identities = 73/243 (30%), Positives = 114/243 (46%), Gaps = 46/243 (18%)
Query: 106 ISKRKVLNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTP 165
+S + + +E+++ +G G +G V ARD VT +L A+KIV
Sbjct: 7 VSLQDPRDRFELLQRVGAGTYGDVYKARDTVTSELAAVKIVKL----------------- 49
Query: 166 QSGIEDEKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIE 225
G + +++EI I+++C H +VV I ++ ++++ +E+C G ++
Sbjct: 50 DPGDDISSLQQEITILRECRHPNVVAYIGSY--LRNDRLWICMEFCGGGSLQEI------ 101
Query: 226 TKARGPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXX 285
A GP L ++ + R L GL +LH QG IHRDIK ANLLL+ G VK++DFGV
Sbjct: 102 YHATGP--LEERQIAYVCREALKGLHHLHSQGKIHRDIKGANLLLTLQGDVKLADFGVSG 159
Query: 286 XXXXXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAM 345
GTP + APE+ VE +L D+WA+
Sbjct: 160 ELTASVAKRRSF-------IGTPYWMAPEVAAVERKGGYNEL------------CDVWAL 200
Query: 346 GIT 348
GIT
Sbjct: 201 GIT 203
>Hs20545357 [T] KOG0583 Serine/threonine protein kinase
Length = 436
Score = 98.2 bits (243), Expect = 6e-20
Identities = 79/292 (27%), Positives = 136/292 (46%), Gaps = 52/292 (17%)
Query: 106 ISKRKVLNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTP 165
I+ K + Y I E+G G +VKL +TK+ VAIKI+++ K D+ + R
Sbjct: 65 ITLGKRIGFYRIRGEIGSGNFSQVKLGIHSLTKEKVAIKILDKTKL----DQKTQRL--- 117
Query: 166 QSGIEDEKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIE 225
+ REI+ M+K HH ++++L EV++ K++LV+EY GE+ I
Sbjct: 118 --------LSREISSMEKLHHPNIIRLYEVVETLS--KLHLVMEYAGGGELF----GKIS 163
Query: 226 TKARGPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXX 285
T+ + LS ++ IF ++ ++++H IIHRD+K N+ + + VK+ DFG
Sbjct: 164 TEGK----LSEPESKLIFSQIVSAVKHMHENQIIHRDLKAENVFYTSNTCVKVGDFGFST 219
Query: 286 XXXXXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAM 345
G+P + APE+ E I DIWA+
Sbjct: 220 VSKKGEMLNTF--------CGSPPYAAPELF--------------RDEHYIGIYVDIWAL 257
Query: 346 GITLHCLLFGMLPFISDYELELFDKIVN-----EPLVFEPYQKIEQCQVSQV 392
G+ L+ ++ G +PF ++ +L I+ P V EP ++ + + Q+
Sbjct: 258 GVLLYFMVTGTMPFRAETVAKLKKSILEGTYSVPPHVSEPCHRLIRGVLQQI 309
>7303211 [T] KOG4717 Serine/threonine protein kinase
Length = 860
Score = 98.2 bits (243), Expect = 6e-20
Identities = 82/279 (29%), Positives = 126/279 (44%), Gaps = 50/279 (17%)
Query: 99 VSLEYDPI---SKRKVLNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFN 155
++LE P+ S K+ Y++ E LG G VKLAR + T VA+K+V+
Sbjct: 1 MTLETQPVGGVSDGKIAGLYDLEETLGSGHFAVVKLARHVFTGAKVAVKVVD-------- 52
Query: 156 DKFSNRFKTPQSGIEDEKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGE 215
KT + + +E+ MK H +VV+L EV+D K+YLVLE G+
Sbjct: 53 -------KTKLDDVSKAHLFQEVRCMKLVQHPNVVRLYEVID--TQTKLYLVLELGDGGD 103
Query: 216 IKWCPGDVIETKARGPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSED-G 274
+ D I G LS + R+ FR +L + Y H ++HRD+KP N++ E G
Sbjct: 104 LY----DYIMKHDSG---LSEELARKYFRQILRAITYCHQLHVVHRDLKPENVVFFEKLG 156
Query: 275 IVKISDFGVXXXXXXXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEP 334
+VK++DFG G+ A+ APEI L + +D
Sbjct: 157 LVKLTDFGFSNKFLPGQKLETF--------CGSLAYSAPEILLGD----SYDAP------ 198
Query: 335 IISFPTDIWAMGITLHCLLFGMLPFISDYELELFDKIVN 373
DIW++G+ L+ L+ G PF + E I++
Sbjct: 199 ----AVDIWSLGVILYMLVCGQAPFEKANDSETLTMIMD 233
>At1g69220 [T] KOG0576 Mitogen-activated protein kinase kinase kinase kinase
(MAP4K) germinal center kinase family
Length = 836
Score = 97.8 bits (242), Expect = 8e-20
Identities = 78/279 (27%), Positives = 124/279 (43%), Gaps = 48/279 (17%)
Query: 97 NTVSLEYDPISKRKVLNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFND 156
+T SL D I++ YE + ELG G +G V ARDL T ++VA+K+++
Sbjct: 232 STTSLP-DSITREDPTTKYEFLNELGKGSYGSVYKARDLKTSEIVAVKVIS--------- 281
Query: 157 KFSNRFKTPQSGIEDEKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEI 216
+ G E+ I+ EI ++++C+H +VV+ + +++V+EYC G +
Sbjct: 282 -----LTEGEEGYEE--IRGEIEMLQQCNHPNVVRYLGSYQGEDY--LWIVMEYCGGGSV 332
Query: 217 KWCPGDVIETKARGPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIV 276
D++ L + I R L GL YLH +HRDIK N+LL+E G V
Sbjct: 333 ----ADLMNVTEEA---LEEYQIAYICREALKGLAYLHSIYKVHRDIKGGNILLTEQGEV 385
Query: 277 KISDFGVXXXXXXXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPII 336
K+ DFGV GTP + APE+ +E
Sbjct: 386 KLGDFGVAAQLTRTMSKRNTF-------IGTPHWMAPEVI---------------QENRY 423
Query: 337 SFPTDIWAMGITLHCLLFGMLPFISDYELELFDKIVNEP 375
D+WA+G++ + G+ P S + + + I EP
Sbjct: 424 DGKVDVWALGVSAIEMAEGLPPRSSVHPMRVLFMISIEP 462
>SPBC12D12.04c [T] KOG0694 Serine/threonine protein kinase
Length = 1016
Score = 97.4 bits (241), Expect = 1e-19
Identities = 85/289 (29%), Positives = 125/289 (42%), Gaps = 51/289 (17%)
Query: 92 PVKETNTVSLEYDPISKRKVLNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKK 151
P ET+ V+ + +KR L + + LG G GKV LA KQL AIK++ +
Sbjct: 660 PSVETSVVAQDLTHKAKRIGLEDFTFLSVLGKGNFGKVMLAELKSEKQLYAIKVLKKE-- 717
Query: 152 RTFNDKFSNRFKTPQSGIEDEKI-KREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEY 210
F +E K KR + + H +V L +IY V+++
Sbjct: 718 ----------FILENDEVESTKSEKRVFLVANRERHPFLVNLHSCFQT--ETRIYFVMDF 765
Query: 211 CSKGEIKWCPGDVIETKARGPPLLSFQRTREIFRG--VLLGLEYLHFQGIIHRDIKPANL 268
S G++ ++ + F R R F V L L+Y H GII+RD+K N+
Sbjct: 766 VSGGDL------MLHIQQE-----QFSRRRAQFYAAEVCLALKYFHDNGIIYRDLKLDNI 814
Query: 269 LLSEDGIVKISDFGVXXXXXXXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLD 328
LLS DG VK++D+G+ A GTP F APEI L + +
Sbjct: 815 LLSPDGHVKVADYGL-------CKEDMWHDNTTATFCGTPEFMAPEILLEQQYTRS---- 863
Query: 329 PNSKEPIISFPTDIWAMGITLHCLLFGMLPFISDYELELFDKIV-NEPL 376
D WA G+ ++ +L G PF + E E+FD I+ +EPL
Sbjct: 864 -----------VDWWAFGVLIYQMLLGQSPFRGEDEEEIFDAILSDEPL 901
>CE28479 [T] KOG0583 Serine/threonine protein kinase
Length = 822
Score = 97.4 bits (241), Expect = 1e-19
Identities = 79/279 (28%), Positives = 123/279 (43%), Gaps = 54/279 (19%)
Query: 112 LNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIED 171
+ Y++ +G G V++AR + K VAIK ++ S ++
Sbjct: 13 IGLYDVGRAIGKGNFATVRIARHKIAKTKVAIKSID------------------VSALDR 54
Query: 172 E---KIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKA 228
E K++RE+ I+K H H+VK E++ +Y+V EYCS GE+ + + K
Sbjct: 55 ENLIKLEREVKIVKVIDHPHIVKSYEIM--RVDNMLYIVSEYCSSGELY----ETLIEKG 108
Query: 229 RGPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXXXXX 288
R ++ R+ F + YLH QGI+HRD+K N+LL ++ +KI DFG
Sbjct: 109 R----VAENVARKWFSETASAVAYLHSQGIVHRDLKAENILLGKNSNIKIIDFGFSNFQT 164
Query: 289 XXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGIT 348
G+P + APE+ L NS + DIW+MG+
Sbjct: 165 GDQLLNT--------WCGSPPYAAPELLL-----------GNSYD---GMKADIWSMGVL 202
Query: 349 LHCLLFGMLPFISDYELELFDKIVNEPLVFEPYQKIEQC 387
L+ L+ G PF SD + + V LV PY +C
Sbjct: 203 LYILVAGGFPFPSD-SVNKLKRSVLSGLVKIPYWVSVEC 240
>7298652 [D] KOG0615 Serine/threonine protein kinase Chk2 and related
proteins
Length = 459
Score = 97.4 bits (241), Expect = 1e-19
Identities = 78/260 (30%), Positives = 120/260 (46%), Gaps = 47/260 (18%)
Query: 110 KVLNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGI 169
++ TY + +LG G +G V+L D T Q A+KIV K + S F P
Sbjct: 152 EINKTYYVNRKLGSGAYGLVRLVYDTRTCQQFAMKIVK--KNMLSGARPSTNFSDP---- 205
Query: 170 EDEKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKAR 229
+++ E IMK H VV++ +++D K +Y+VLE+ G++ +I K
Sbjct: 206 --DRVLNEAKIMKNLSHPCVVRMHDIVD--KPDSVYMVLEFMRGGDLL---NRIISNK-- 256
Query: 230 GPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLL---SEDGIVKISDFGVXXX 286
LLS ++ F + ++YLH +GI HRD+KP N+LL E+ ++K+SDFG+
Sbjct: 257 ---LLSEDISKLYFYQMCHAVKYLHDRGITHRDLKPDNVLLETNDEETLLKVSDFGLSKF 313
Query: 287 XXXXXXXXXXXXXXXAKTAGTPAFFAPEICLV---EDTIKKFDLDPNSKEPIISFPTDIW 343
GTP + APE+ + E KK DIW
Sbjct: 314 VQKDSVMRT--------LCGTPLYVAPEVLITGGREAYTKK---------------VDIW 350
Query: 344 AMGITLHCLLFGMLPFISDY 363
++G+ L L G LPF +Y
Sbjct: 351 SLGVVLFTCLSGTLPFSDEY 370
>YPL153c [D] KOG0615 Serine/threonine protein kinase Chk2 and related
proteins
Length = 821
Score = 96.7 bits (239), Expect = 2e-19
Identities = 89/363 (24%), Positives = 155/363 (42%), Gaps = 54/363 (14%)
Query: 69 LHQNHIRTVLGSHLNSGQRITYGPVKETNTVSLEYDPISKRKVLNTYEIIEEL-GHGQHG 127
L QN + + + N+ + + G T + + +K + + II+E+ G G
Sbjct: 155 LEQNKVDRIRSNLKNTSKIASPGLTSSTASSMVA----NKTGIFKDFSIIDEVVGQGAFA 210
Query: 128 KVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIEDEKIKREIAIMKKCHHE 187
VK A + T + A+KI+++ K D + RE+ +++K +H
Sbjct: 211 TVKKAIERTTGKTFAVKIISKRKVIGNMDG----------------VTRELEVLQKLNHP 254
Query: 188 HVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKARGPPLLSFQRTREIFRGVL 247
+V+L +D +S Y+V+E+ S G++ D + + REI R +L
Sbjct: 255 RIVRLKGFYEDTES--YYMVMEFVSGGDLM----DFVAAHGA----VGEDAGREISRQIL 304
Query: 248 LGLEYLHFQGIIHRDIKPANLLLSEDG--IVKISDFGVXXXXXXXXXXXXXXXXXXAKTA 305
++Y+H GI HRD+KP N+L+ +D +VKI+DFG+
Sbjct: 305 TAIKYIHSMGISHRDLKPDNILIEQDDPVLVKITDFGLAKVQGNGSFMKTF--------C 356
Query: 306 GTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGITLHCLLFGMLPFISDYEL 365
GT A+ APE+ +DT D + S D+W+MG ++ +L G LPF +
Sbjct: 357 GTLAYVAPEVIRGKDT--SVSPDEYEERNEYSSLVDMWSMGCLVYVILTGHLPFSGSTQD 414
Query: 366 ELFDKIVNEPLVFEPYQKIEQCQVSQVECKEEYEEAQXXXXXXXXXXXXXRMAIQDAKKH 425
+L+ +I P ++ ++S EEA+ R A H
Sbjct: 415 QLYKQIGRGSYHEGP---LKDFRIS--------EEARDFIDSLLQVDPNNRSTAAKALNH 463
Query: 426 PWV 428
PW+
Sbjct: 464 PWI 466
>Hs7706059 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 455
Score = 96.7 bits (239), Expect = 2e-19
Identities = 77/261 (29%), Positives = 115/261 (43%), Gaps = 47/261 (18%)
Query: 112 LNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIED 171
+ YE + ++G G +G V + T Q+VAIKI +++ N
Sbjct: 1 MEMYETLGKVGEGSYGTVMKCKHKNTGQIVAIKIFYERPEQSVN---------------- 44
Query: 172 EKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKARGP 231
+ REI +K+ HHE++V LIEV K KI+LV E+ + D ++ G
Sbjct: 45 KIAMREIKFLKQFHHENLVNLIEVFRQKK--KIHLVFEFIDHTVL-----DELQHYCHG- 96
Query: 232 PLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXXXXXXXX 291
L +R R+ +L ++YLH IIHRDIKP N+L+S+ GI K+ DFG
Sbjct: 97 --LESKRLRKYLFQILRAIDYLHSNNIIHRDIKPENILVSQSGITKLCDFGFARTLAAPG 154
Query: 292 XXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGITLHC 351
T + APE+ L + + K P DIWA+G +
Sbjct: 155 DIYTDY-------VATRWYRAPELVLKDTSYGK--------------PVDIWALGCMIIE 193
Query: 352 LLFGMLPFISDYELELFDKIV 372
+ G S +L+L KIV
Sbjct: 194 MATGNPYLPSSSDLDLLHKIV 214
>CE09360 [Z] KOG0613 Projectin/twitchin and related proteins
Length = 2783
Score = 96.7 bits (239), Expect = 2e-19
Identities = 82/333 (24%), Positives = 135/333 (39%), Gaps = 66/333 (19%)
Query: 102 EYDPISKRKVLNT----YEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDK 157
EY I ++ N Y I EELG G +G V A + T + A K+V
Sbjct: 178 EYKTIDIHRLPNDLQAKYIIHEELGKGAYGTVYRATEKATGKTWAAKMVQ---------- 227
Query: 158 FSNRFKTPQSGIEDEKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIK 217
+ G++ E + EI++M + HHE ++ L E D +++L+ E+ S GE+
Sbjct: 228 -------VRPGVKKENVIHEISMMNQLHHEKLLNLHEAFD--MGNEMWLIEEFVSGGEL- 277
Query: 218 WCPGDVIETKARGPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLL--SEDGI 275
E L+S + R+ +LLG+ ++H I+H D+KP N+LL
Sbjct: 278 ------FEKILEDDSLMSEEEVRDYMHQILLGVSHMHKNQIVHLDLKPENILLKAKNSNE 331
Query: 276 VKISDFGVXXXXXXXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPI 335
+KI DFG+ GTP F APE+ +
Sbjct: 332 LKIIDFGLARKLDPKKSVKLLF--------GTPEFCAPEVVNYQP--------------- 368
Query: 336 ISFPTDIWAMGITLHCLLFGMLPFISDYELELFDKIVNEPLVFEPYQKIEQCQVSQVECK 395
+ TD+W +G+ + LL G+ PF+ D + + + F+
Sbjct: 369 VGLSTDMWTVGVISYVLLSGLSPFLGDSDEDTLANVSASDWDFD-----------DPSWD 417
Query: 396 EEYEEAQXXXXXXXXXXXXXRMAIQDAKKHPWV 428
+ + A+ RM++QDA +HPW+
Sbjct: 418 DVSDLAKDFICRLMIKDKRKRMSVQDALRHPWI 450
>At1g78290 [T] KOG0583 Serine/threonine protein kinase
Length = 343
Score = 96.7 bits (239), Expect = 2e-19
Identities = 82/320 (25%), Positives = 131/320 (40%), Gaps = 65/320 (20%)
Query: 112 LNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIED 171
+ YEI++++G G G KL RD +K+L A+K + R +K D
Sbjct: 1 MERYEIVKDIGSGNFGVAKLVRDKFSKELFAVKFIERGQK------------------ID 42
Query: 172 EKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEI--KWCPGDVIETKAR 229
E ++REI + H ++++ EVL + + LV+EY + GE+ + C
Sbjct: 43 EHVQREIMNHRSLIHPNIIRFKEVL--LTATHLALVMEYAAGGELFGRICSAG------- 93
Query: 230 GPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLL--SEDGIVKISDFGVXXXX 287
S R F+ ++ G+ Y H I HRD+K N LL SE VKI DFG
Sbjct: 94 ---RFSEDEARFFFQQLISGVNYCHSLQICHRDLKLENTLLDGSEAPRVKICDFGYSKSG 150
Query: 288 XXXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGI 347
T GTPA+ APE+ ++ K D+W+ G+
Sbjct: 151 VLHSQPKT--------TVGTPAYIAPEVLSTKEYDGKI--------------ADVWSCGV 188
Query: 348 TLHCLLFGMLPFISDYELELFDKIVNEPLVFEPYQKIEQCQVSQVECKEEYEEAQXXXXX 407
TL+ +L G PF + + F K + +I + Q + + +E +
Sbjct: 189 TLYVMLVGAYPFEDPSDPKDFRKTIG---------RILKAQYAIPDYVRVSDECRHLLSR 239
Query: 408 XXXXXXXXRMAIQDAKKHPW 427
R+ I++ K H W
Sbjct: 240 IFVANPEKRITIEEIKNHSW 259
>At1g12680 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 470
Score = 96.7 bits (239), Expect = 2e-19
Identities = 87/327 (26%), Positives = 143/327 (43%), Gaps = 77/327 (23%)
Query: 108 KRKVLNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQS 167
K K+ + Y +G G+ G V++ K R +F+ KT +
Sbjct: 100 KNKIDDDYVFGRNIGKGKFGSVRIC-----------------KSRKNGTEFA--CKTLKK 140
Query: 168 GIEDEKIKREIAIMKKCH-HEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIET 226
G +E + RE+ IM+ H VV L V +++ +LV+E CS G + D +
Sbjct: 141 G--EETVHREVEIMQHLSGHPRVVTLHAVYEESDC--FHLVMELCSGGRLI----DQMVK 192
Query: 227 KARGPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXXX 286
R S QR IF+ ++L + Y H G++HRDIKP N+LL+ G ++++DFG+
Sbjct: 193 VGR----YSEQRAANIFKDLMLVINYCHEMGVVHRDIKPENILLTAAGKIQLADFGL--- 245
Query: 287 XXXXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMG 346
+ AG+PA+ APE+ L N E + D+W+ G
Sbjct: 246 -----AMRIAKGQTLSGLAGSPAYVAPEV-----------LSENYSEKV-----DVWSAG 284
Query: 347 ITLHCLLFGMLPFISDYELELFDKIVNEPL-----VFEPYQKIEQCQVSQVECKEEYEEA 401
+ L+ LL G+LPF D +F+ I N L V+E K + ++++ +EE
Sbjct: 285 VLLYALLSGVLPFKGDSLDAIFEAIKNVKLDFNTGVWESVSKPARDLLARMLTREE---- 340
Query: 402 QXXXXXXXXXXXXXRMAIQDAKKHPWV 428
R+ + +HPW+
Sbjct: 341 ------------SARITADEVLRHPWI 355
>Hs4826684_1 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 370
Score = 96.7 bits (239), Expect = 2e-19
Identities = 87/323 (26%), Positives = 134/323 (40%), Gaps = 69/323 (21%)
Query: 115 YEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIEDEKI 174
Y+ EELG GQ VK R+ T A K + KKR R K+ + G+ E I
Sbjct: 13 YDTGEELGSGQFAVVKKCREKSTGLQYAAKFI---KKR--------RTKSSRRGVSREDI 61
Query: 175 KREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKARGPPLL 234
+RE++I+K+ H +V+ L EV ++ + L+LE + GE+ D + K L
Sbjct: 62 EREVSILKEIQHPNVITLHEVYENKTD--VILILELVAGGELF----DFLAEKES----L 111
Query: 235 SFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGI----VKISDFGVXXXXXXX 290
+ + E + +L G+ YLH I H D+KP N++L + + +KI DFG+
Sbjct: 112 TEEEATEFLKQILNGVYYLHSLQIAHFDLKPENIMLLDRNVPKPRIKIIDFGL------- 164
Query: 291 XXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGITLH 350
GTP F APEI E + D+W++G+ +
Sbjct: 165 -AHKIDFGNEFKNIFGTPEFVAPEIVNYEP---------------LGLEADMWSIGVITY 208
Query: 351 CLLFGMLPFISDYELELFDKIVNEPLVFEPYQKIEQCQVSQVECKEEYEE-----AQXXX 405
LL G PF+ D + E + E ++EY A+
Sbjct: 209 ILLSGASPFLGDTKQETLANV----------------SAVNYEFEDEYFSNTSALAKDFI 252
Query: 406 XXXXXXXXXXRMAIQDAKKHPWV 428
RM IQD+ +HPW+
Sbjct: 253 RRLLVKDPKKRMTIQDSLQHPWI 275
>Hs9966875 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 357
Score = 96.3 bits (238), Expect = 2e-19
Identities = 98/398 (24%), Positives = 161/398 (39%), Gaps = 82/398 (20%)
Query: 115 YEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIEDEKI 174
+E E LG G +V LA + T +L A+K + + K +S IE+E
Sbjct: 23 FEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPK-----------KALKGKESSIENE-- 69
Query: 175 KREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKARGPPLL 234
IA+++K HE++V L ++ + +YLV++ S GE+ D I K
Sbjct: 70 ---IAVLRKIKHENIVALEDIYESPNH--LYLVMQLVSGGELF----DRIVEKG----FY 116
Query: 235 SFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLL---SEDGIVKISDFGVXXXXXXXX 291
+ + + R VL + YLH GI+HRD+KP NLL E+ + ISDFG+
Sbjct: 117 TEKDASTLIRQVLDAVYYLHRMGIVHRDLKPENLLYYSQDEESKIMISDFGL-------- 168
Query: 292 XXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGITLHC 351
+ GTP + APE+ + P SK D W++G+ +
Sbjct: 169 SKMEGKGDVMSTACGTPGYVAPEVLAQK---------PYSK------AVDCWSIGVIAYI 213
Query: 352 LLFGMLPFISDYELELFDKIVNEPLVFE-PYQKIEQCQVSQVECKEEYEEAQXXXXXXXX 410
LL G PF + + +LF++I+ F+ PY + + A+
Sbjct: 214 LLCGYPPFYDENDSKLFEQILKAEYEFDSPY------------WDDISDSAKDFIRNLME 261
Query: 411 XXXXXRMAIQDAKKHPWVCWDFNHNDYMSDQEKSLKLIEQSNFHRSPSEQVEQICISE-- 468
R + A +HPW+ D N N H S S Q+ +
Sbjct: 262 KDPNKRYTCEQAARHPWIAGDTALN---------------KNIHESVSAQIRKNFAKSKW 306
Query: 469 HEVDTAVGGIGHKIKNAVGKFLPSTKSNDESNTNSVNE 506
+ A + H K +G L S+ ++ S+ + ++
Sbjct: 307 RQAFNATAVVRHMRKLHLGSSLDSSNASVSSSLSLASQ 344
>Hs4826878 [T] KOG0582 Ste20-like serine/threonine protein kinase
Length = 527
Score = 96.3 bits (238), Expect = 2e-19
Identities = 76/247 (30%), Positives = 109/247 (43%), Gaps = 38/247 (15%)
Query: 115 YEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIEDEKI 174
YE+ E +G G V+ A K+ VAIK +N K +T D+ +
Sbjct: 17 YELQEVIGSGATAVVQAAYCAPKKEKVAIKRINLEKCQTSMDE----------------L 60
Query: 175 KREIAIMKKCHHEHVVKLIE--VLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKARGPP 232
+EI M +CHH ++V V+ D +++LV++ S G + ++
Sbjct: 61 LKEIQAMSQCHHPNIVSYYTSFVVKD----ELWLVMKLLSGGSVLDIIKHIVAKGEHKSG 116
Query: 233 LLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXXXXXXXXX 292
+L I R VL GLEYLH G IHRD+K N+LL EDG V+I+DFGV
Sbjct: 117 VLDESTIATILREVLEGLEYLHKNGQIHRDVKAGNILLGEDGSVQIADFGVSAFLATGGD 176
Query: 293 XXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGITLHCL 352
GTP + APE V + ++ +D F DIW+ GIT L
Sbjct: 177 ITRNKVRKT--FVGTPCWMAPE---VMEQVRGYD-----------FKADIWSFGITAIEL 220
Query: 353 LFGMLPF 359
G P+
Sbjct: 221 ATGAAPY 227
>YPL203w [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 380
Score = 95.9 bits (237), Expect = 3e-19
Identities = 73/278 (26%), Positives = 124/278 (44%), Gaps = 52/278 (18%)
Query: 106 ISKRK-VLNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKT 164
+SK K L+ ++I+ LG G G+V L R + + AIK++ + +
Sbjct: 60 VSKGKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKQQVVKMK--------- 110
Query: 165 PQSGIEDEKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVI 224
+ E E ++K H ++++ DA R I++V++Y GE+ ++
Sbjct: 111 -----QVEHTNDERRMLKLVEHPFLIRMWGTFQDA--RNIFMVMDYIEGGELF----SLL 159
Query: 225 ETKARGP-PLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGV 283
R P P+ F V+L LEYLH II+RD+KP N+LL +G +KI+DFG
Sbjct: 160 RKSQRFPNPVAKFYAAE-----VILALEYLHAHNIIYRDLKPENILLDRNGHIKITDFGF 214
Query: 284 XXXXXXXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIW 343
GTP + APE+ + P +K D W
Sbjct: 215 AKEVQTVTWT----------LCGTPDYIAPEVITTK---------PYNKS------VDWW 249
Query: 344 AMGITLHCLLFGMLPFISDYELELFDKIVNEPLVFEPY 381
++G+ ++ +L G PF ++ ++KI+ +V+ PY
Sbjct: 250 SLGVLIYEMLAGYTPFYDTTPMKTYEKILQGKVVYPPY 287
>Hs14589909 [T] KOG0576 Mitogen-activated protein kinase kinase kinase kinase
(MAP4K) germinal center kinase family
Length = 846
Score = 95.9 bits (237), Expect = 3e-19
Identities = 76/243 (31%), Positives = 114/243 (46%), Gaps = 46/243 (18%)
Query: 106 ISKRKVLNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTP 165
I +R YE+++ +G G +G V AR++ T +L A+KI+ K D FS
Sbjct: 11 ILRRNPQQDYELVQRVGSGTYGDVYKARNVHTGELAAVKII----KLEPGDDFS------ 60
Query: 166 QSGIEDEKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIE 225
I++EI ++K+C H ++V K+++ +EYC G ++ D+
Sbjct: 61 -------LIQQEIFMVKECKHCNIVAYFGSY--LSREKLWICMEYCGGGSLQ----DIYH 107
Query: 226 TKARGPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXX 285
GP LS + + R L GL YLH +G +HRDIK AN+LL++ G VK++DFGV
Sbjct: 108 VT--GP--LSELQIAYVCRETLQGLAYLHTKGKMHRDIKGANILLTDHGDVKLADFGVAA 163
Query: 286 XXXXXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAM 345
GTP + APE+ VE K + DIWA+
Sbjct: 164 KITATIAKRKSF-------IGTPYWMAPEVAAVE------------KNGGYNQLCDIWAV 204
Query: 346 GIT 348
GIT
Sbjct: 205 GIT 207
>YAR019c [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 974
Score = 95.5 bits (236), Expect = 4e-19
Identities = 77/260 (29%), Positives = 120/260 (45%), Gaps = 51/260 (19%)
Query: 115 YEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIEDEKI 174
Y + + +G G +G V A + T Q+VAIK V ND I
Sbjct: 25 YHLKQVIGRGSYGVVYKAINKHTDQVVAIKEVVYENDEELND-----------------I 67
Query: 175 KREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKARGPPLL 234
EI+++K +H ++VK + KS ++Y++LEYC+ G ++ +I + G L
Sbjct: 68 MAEISLLKNLNHNNIVKYHGFI--RKSYELYILLEYCANGSLR----RLISRSSTG---L 118
Query: 235 SFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXXXXXXXXXXX 294
S ++ LLGL+YLH +G+IHRDIK AN+LLS D VK++DFGV
Sbjct: 119 SENESKTYVTQTLLGLKYLHGEGVIHRDIKAANILLSADNTVKLADFGVSTIVNSSALT- 177
Query: 295 XXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGITLHCLLF 354
AGT + APEI N +S DIW++G T+ +L
Sbjct: 178 ---------LAGTLNWMAPEIL------------GNRGASTLS---DIWSLGATVVEMLT 213
Query: 355 GMLPFISDYELELFDKIVNE 374
P+ + + ++ + N+
Sbjct: 214 KNPPYHNLTDANIYYAVEND 233
>Hs5454096 [T] KOG0574 STE20-like serine/threonine kinase MST
Length = 487
Score = 95.5 bits (236), Expect = 4e-19
Identities = 78/275 (28%), Positives = 123/275 (44%), Gaps = 51/275 (18%)
Query: 101 LEYDPISKRKVLNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSN 160
L+ D ++K+ ++++E+LG G +G V A T Q+VAIK V
Sbjct: 17 LDEDSLTKQPE-EVFDVLEKLGEGSYGSVYKAIHKETGQIVAIKQV-------------- 61
Query: 161 RFKTPQSGIEDEKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCP 220
+S +++ I +EI+IM++C HVVK K+ +++V+EYC G +
Sbjct: 62 ---PVESDLQE--IIKEISIMQQCDSPHVVKYYGSY--FKNTDLWIVMEYCGAGSVS--- 111
Query: 221 GDVIETKARGPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISD 280
D+I + + L+ I + L GLEYLHF IHRDIK N+LL+ +G K++D
Sbjct: 112 -DIIRLRNK---TLTEDEIATILQSTLKGLEYLHFMRKIHRDIKAGNILLNTEGHAKLAD 167
Query: 281 FGVXXXXXXXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPT 340
FGV GTP + APE+ +E +
Sbjct: 168 FGVAGQLTDTMAKRNT-------VIGTPFWMAPEVI---------------QEIGYNCVA 205
Query: 341 DIWAMGITLHCLLFGMLPFISDYELELFDKIVNEP 375
DIW++GIT + G P+ + + I P
Sbjct: 206 DIWSLGITAIEMAEGKPPYADIHPMRAIFMIPTNP 240
>At5g04510 [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 488
Score = 95.5 bits (236), Expect = 4e-19
Identities = 79/267 (29%), Positives = 118/267 (43%), Gaps = 42/267 (15%)
Query: 115 YEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIEDEKI 174
+E + G G + KV A+ T + A+KI+++ +F T ++ + +
Sbjct: 41 FEFGKIYGVGSYSKVVRAKKKETGTVYALKIMDK------------KFITKEN--KTAYV 86
Query: 175 KREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKARGPPLL 234
K E ++ + H ++KL D S +Y+ LE C GE+ D I K R L
Sbjct: 87 KLERIVLDQLEHPGIIKLYFTFQDTSS--LYMALESCEGGELF----DQITRKGR----L 136
Query: 235 SFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXXXXXXXXXXX 294
S R V+ LEY+H G+IHRDIKP NLLL+ DG +KI+DFG
Sbjct: 137 SEDEARFYTAEVVDALEYIHSMGLIHRDIKPENLLLTSDGHIKIADFGSVKPMQDSQITV 196
Query: 295 XXXXXXXAKT---AGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGITLHC 351
K GT A+ PE+ NS +F D+WA+G TL+
Sbjct: 197 LPNAASDDKACTFVGTAAYVPPEVL-------------NSSP--ATFGNDLWALGCTLYQ 241
Query: 352 LLFGMLPFISDYELELFDKIVNEPLVF 378
+L G PF E +F +I+ + F
Sbjct: 242 MLSGTSPFKDASEWLIFQRIIARDIKF 268
>YPL141c [T] KOG0583 Serine/threonine protein kinase
Length = 865
Score = 95.1 bits (235), Expect = 5e-19
Identities = 85/291 (29%), Positives = 127/291 (43%), Gaps = 60/291 (20%)
Query: 108 KRKVLNTYEIIEELGHGQHGKVKLA----------RDLVTKQLVAIKIVNRHKKRTFNDK 157
K Y + LG G+ GKVKL + VAIK++ R D
Sbjct: 34 KHVTFGPYILGSTLGEGEFGKVKLGWPKNFSNSSNSTFDFPKQVAIKLIKR-------DS 86
Query: 158 FSNRFKTPQSGIEDEKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIK 217
SN ++ ++ KI REI +K H ++VKL EVL + SR I +VLEY GE
Sbjct: 87 ISNDYR------KEVKIYREINALKHLSHPNIVKLEEVLQN--SRYIGIVLEYACGGEFY 138
Query: 218 WCPGDVIETKARGPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVK 277
I+ K R L +F ++ G+ Y+H +G++HRD+K NLLL ++ +
Sbjct: 139 ----KYIQKKRR----LKEMNACRLFSQLISGVHYIHSKGLVHRDLKLENLLLDKNENLV 190
Query: 278 ISDFGVXXXXXXXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIIS 337
I+DFG + G+P + APE+ + S EP +
Sbjct: 191 ITDFGFVNEFCSRNELMKT-------SCGSPCYAAPELVI-------------SAEPYEA 230
Query: 338 FPTDIWAMGITLHCLLFGMLPFISDYEL-------ELFDKIVNEPLVFEPY 381
DIW+ G+ L+ +L G LP+ D L++ I + PL F Y
Sbjct: 231 RKADIWSCGVILYAILAGYLPWDDDPNNPEGSDIGRLYNYINSTPLKFPDY 281
>Hs15451902 [T] KOG0576 Mitogen-activated protein kinase kinase kinase kinase
(MAP4K) germinal center kinase family
Length = 894
Score = 95.1 bits (235), Expect = 5e-19
Identities = 70/243 (28%), Positives = 116/243 (46%), Gaps = 46/243 (18%)
Query: 106 ISKRKVLNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTP 165
+S+R +E+I+ +G G +G V AR++ T +L AIK++
Sbjct: 7 LSRRNPQEDFELIQRIGSGTYGDVYKARNVNTGELAAIKVIKL----------------- 49
Query: 166 QSGIEDEKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIE 225
+ G + +++EI +MK C H ++V + K+++ +E+C G ++ D+
Sbjct: 50 EPGEDFAVVQQEIIMMKDCKHPNIVAYFGSY--LRRDKLWICMEFCGGGSLQ----DIYH 103
Query: 226 TKARGPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXX 285
GP LS + + R L GL YLH +G +HRDIK AN+LL+++G VK++DFGV
Sbjct: 104 VT--GP--LSELQIAYVSRETLQGLYYLHSKGKMHRDIKGANILLTDNGHVKLADFGVSA 159
Query: 286 XXXXXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAM 345
GTP + APE+ VE ++ + D+WA+
Sbjct: 160 QITATIAKRKSF-------IGTPYWMAPEVAAVE------------RKGGYNQLCDLWAV 200
Query: 346 GIT 348
GIT
Sbjct: 201 GIT 203
>CE26793_1 [R] KOG0611 Predicted serine/threonine protein kinase
Length = 795
Score = 95.1 bits (235), Expect = 5e-19
Identities = 91/395 (23%), Positives = 154/395 (38%), Gaps = 64/395 (16%)
Query: 109 RKVLNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSG 168
+K + +EI ++LG G +GKV LA D + VA+K++ + +S
Sbjct: 69 KKEKHRFEITKKLGSGTYGKVSLAYDHKFDREVAVKLIKK--------------SAIESK 114
Query: 169 IEDEKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKA 228
+ +I+REI IM +H +++++ EV ++ KI LV+EY S GE+ D +
Sbjct: 115 ADLVRIRREIRIMSALNHPNIIQIYEVFENKD--KIILVMEYSSGGELY----DYVSRCG 168
Query: 229 RGPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXXXXX 288
P R IFR + + Y H + HRD+K N+LL ++ KI+DFG+
Sbjct: 169 SLPEA----EARRIFRQITSAVLYCHKHRVAHRDLKLENILLDQNNNAKIADFGLSNYFA 224
Query: 289 XXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGIT 348
G+P + +PEI + P D W++GI
Sbjct: 225 DKNLLTTF--------CGSPLYASPEII--------------NGTPYKGPEVDCWSLGIL 262
Query: 349 LHCLLFGMLPFISDYELELFDKIVNEPLVFEPYQKIEQCQVSQVECKEEYEEAQXXXXXX 408
L+ L++G +PF + + + FEP E A
Sbjct: 263 LYTLVYGSMPF-DGRDFNRMVRQIKRGAYFEP---------------ETPSTASMLIRNM 306
Query: 409 XXXXXXXRMAIQDAKKHPWVCWDFNHNDYMSDQEKSLKLIEQSNFHRSPSEQVEQICISE 468
R I D H W+ + N + + ++I+ + + Q E
Sbjct: 307 LRVNPERRATIFDIASHWWL--NLEENMPVIQELPENQIIDHTPLTEREETMIVQDLADE 364
Query: 469 HEVDTAVGGIGHKIKNAVGKFLPSTKSNDESNTNS 503
+V G + + + + F K +E N NS
Sbjct: 365 QDVFMEFGHLSSETRRKIEDFRIRRKEAEEFNDNS 399
>YOR233w [T] KOG0583 Serine/threonine protein kinase
Length = 800
Score = 94.7 bits (234), Expect = 7e-19
Identities = 91/335 (27%), Positives = 141/335 (41%), Gaps = 90/335 (26%)
Query: 60 QRQRQLNHPLHQNHIRTVLGSHLNSGQRITYGPVKETNTVSLEYDPISKRKVLNTYEIIE 119
QR ++ HP+H+N + T+GP Y I
Sbjct: 24 QRNNEILHPIHKNQRK-----------HATFGP----------------------YIIGS 50
Query: 120 ELGHGQHGKVKL------ARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIEDEK 173
LG G+ GKVKL + + V KQ VAIK++ R + DK + K
Sbjct: 51 TLGEGEFGKVKLGWTKASSSNEVPKQ-VAIKLIRRDTIKKDADK-------------EIK 96
Query: 174 IKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKARGPPL 233
I REI +K H +++ L EVL ++K I +VLE+ S GE I+ K R
Sbjct: 97 IYREINALKHLTHPNIIYLEEVLQNSKY--IGIVLEFVSGGEFY----KYIQRKRR---- 146
Query: 234 LSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXXXXXXXXXX 293
L +F ++ G+ Y+H++G++HRD+K NLLL + + I+DFG
Sbjct: 147 LKESSACRLFAQLISGVNYMHYKGLVHRDLKLENLLLDKHENLVITDFGFVNEFFEDNEL 206
Query: 294 XXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGITLHCLL 353
+ G+P + APE+ + S + + D+W+ G+ L+ +L
Sbjct: 207 MKT-------SCGSPCYAAPELVV-------------STKAYEARKADVWSCGVILYAML 246
Query: 354 FGMLPFISDYE-------LELFDKIVNEPLVFEPY 381
G LP+ D+E L+ I PL F Y
Sbjct: 247 AGYLPWDDDHENPTGDDIARLYKYITQTPLKFPEY 281
>Hs14149671 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 1734
Score = 94.7 bits (234), Expect = 7e-19
Identities = 76/282 (26%), Positives = 119/282 (41%), Gaps = 47/282 (16%)
Query: 105 PISKRKVLNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKT 164
P K +E I+ + +G +G V L R T+Q A+K +N+ N
Sbjct: 502 PSKKTPSEEDFETIKLISNGAYGAVFLVRHKSTRQRFAMKKINKQNLILRNQ-------- 553
Query: 165 PQSGIEDEKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVI 224
I+ ++R+I + + VV + D R + +V+EY G+
Sbjct: 554 ----IQQAFVERDILTFAE--NPFVVSMFCSFDT--KRHLCMVMEYVEGGDCA------- 598
Query: 225 ETKARGPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVX 284
T + L R F +L LEYLH GI+HRD+KP NLL++ G +K++DFG+
Sbjct: 599 -TLLKNIGALPVDMVRLYFAETVLALEYLHNYGIVHRDLKPDNLLITSMGHIKLTDFGLS 657
Query: 285 XXXXXXXXX--------XXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPII 336
+ GTP + APE+ L + K
Sbjct: 658 KMGLMSLTTNLYEGHIEKDAREFLDKQVCGTPEYIAPEVILRQGYGK------------- 704
Query: 337 SFPTDIWAMGITLHCLLFGMLPFISDYELELFDKIVNEPLVF 378
P D WAMGI L+ L G +PF D ELF +++++ +V+
Sbjct: 705 --PVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVISDEIVW 744
>CE25046 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 348
Score = 94.7 bits (234), Expect = 7e-19
Identities = 85/329 (25%), Positives = 135/329 (40%), Gaps = 67/329 (20%)
Query: 105 PISKRKVLNTYEIIEELGHGQHGKVKLARDLVTK-QLVAIKIVNRHKKRTFNDKFSNRFK 163
P + Y+ + LG G KV LA Q+ A+K ++ K+ K
Sbjct: 12 PAPNATIREKYDFRDVLGTGAFSKVFLAESKSDAGQMYAVKCID---KKALKGK------ 62
Query: 164 TPQSGIEDEKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDV 223
+E ++ EI +++K H ++V+L + D+ + +YLV+E + GE+ D
Sbjct: 63 -------EESLENEIKVLRKLRHNNIVQLFDTYDEKQF--VYLVMELVTGGELF----DR 109
Query: 224 IETKARGPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLL---SEDGIVKISD 280
I K + Q + R VL + ++H G++HRD+KP NLL ED + ISD
Sbjct: 110 IVAKGS----YTEQDASNLIRQVLEAVGFMHDNGVVHRDLKPENLLYYNQDEDSKIMISD 165
Query: 281 FGVXXXXXXXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPT 340
FG+ A GTP + APE+ P K
Sbjct: 166 FGL---------SKTEDSGVMATACGTPGYVAPEV---------LQQKPYGK------AV 201
Query: 341 DIWAMGITLHCLLFGMLPFISDYELELFDKIVNEPLVFE-PYQKIEQCQVSQVECKEEYE 399
D+W++G+ + LL G PF + + LF +I+ F+ PY Q+S +
Sbjct: 202 DVWSIGVIAYILLCGYPPFYDESDANLFAQIIKGEYEFDAPYWD----QIS--------D 249
Query: 400 EAQXXXXXXXXXXXXXRMAIQDAKKHPWV 428
A+ R QDA HPW+
Sbjct: 250 SAKDFITHLMCCDPEARFTCQDALSHPWI 278
>7297080 [T] KOG0583 Serine/threonine protein kinase
Length = 329
Score = 94.7 bits (234), Expect = 7e-19
Identities = 75/291 (25%), Positives = 137/291 (46%), Gaps = 46/291 (15%)
Query: 92 PVKETNTVSLEYDPISK--RKVLNTYEII--EELGHGQHGKVKLARDLVTKQLVAIKIVN 147
P + V ++ D SK + +L + II + +G G + KVK+ + VA+KI++
Sbjct: 41 PPAPSGVVPVKADDKSKPQKTILEEHGIILGKVIGTGNYAKVKIGFSEEYGKRVAVKIIS 100
Query: 148 RHKKRTFNDKFSNRFKTPQSGIEDEKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLV 207
+ K + +++ +F + REI +K HHE+++ + ++ S ++YL+
Sbjct: 101 KVKAPS---EYTQKF-----------LPREIEAVKGLHHENLITFYQSIET--SHRVYLI 144
Query: 208 LEYCSKGEIKWCPGDVIETKARGPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPAN 267
++ G + R L ++R +F+ ++ +EY+H +G++HRDIK N
Sbjct: 145 MQLAENGTLL--------DYVRERKFLDEPQSRTLFKQLVSAVEYIHSKGVVHRDIKCEN 196
Query: 268 LLLSEDGIVKISDFGVXXXXXXXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDL 327
LLL E+ +K+ DFG G+ A+ +PEI +K
Sbjct: 197 LLLDENWNLKLIDFGFARKDTRTSDNQVILSKTF---CGSYAYASPEI------LKGVAY 247
Query: 328 DPNSKEPIISFPTDIWAMGITLHCLLFGMLPFISDYELELFDKIVNEPLVF 378
DP F +DIWA G+ + ++FG LP+ + + K +N+ LVF
Sbjct: 248 DP--------FMSDIWACGVVCYAMVFGRLPY-DGSNVHILLKRINQSLVF 289
>At4g33950 [T] KOG0583 Serine/threonine protein kinase
Length = 357
Score = 94.4 bits (233), Expect = 9e-19
Identities = 85/352 (24%), Positives = 141/352 (39%), Gaps = 66/352 (18%)
Query: 115 YEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIEDEKI 174
YE+++++G G G +L RD + +LVA+K + R +K DE +
Sbjct: 21 YELVKDIGSGNFGVARLMRDKQSNELVAVKYIERGEK------------------IDENV 62
Query: 175 KREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKARGPPLL 234
KREI + H ++V+ EV+ + +V+EY S GE + +
Sbjct: 63 KREIINHRSLRHPNIVRFKEVI--LTPTHLAIVMEYASGGE--------LFERICNAGRF 112
Query: 235 SFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLL--SEDGIVKISDFGVXXXXXXXXX 292
S R F+ ++ G+ Y H + HRD+K N LL S +KI DFG
Sbjct: 113 SEDEARFFFQQLISGVSYCHAMQVCHRDLKLENTLLDGSPAPRLKICDFG--------YS 164
Query: 293 XXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGITLHCL 352
T GTPA+ APE+ L ++ K D+W+ G+TL+ +
Sbjct: 165 KSSVLHSQPKSTVGTPAYIAPEVLLKKEYDGKV--------------ADVWSCGVTLYVM 210
Query: 353 LFGMLPFISDYELELFDKIVNEPLVFEPYQKIEQCQVSQVECKEEYEEAQXXXXXXXXXX 412
L G PF E + F K ++ +I Q + + E +
Sbjct: 211 LVGAYPFEDPEEPKNFRKTIH---------RILNVQYAIPDYVHISPECRHLISRIFVAD 261
Query: 413 XXXRMAIQDAKKHPWVCWDFNHNDYMSDQEKSLKLIEQSNFHRSPSEQVEQI 464
R++I + + H W + D M+D + + E P + +E+I
Sbjct: 262 PAKRISIPEIRNHEWFLKNL-PADLMNDNTMTTQFDESD----QPGQSIEEI 308
>At4g32830 [D] KOG0580 Serine/threonine protein kinase
Length = 294
Score = 94.4 bits (233), Expect = 9e-19
Identities = 83/324 (25%), Positives = 143/324 (43%), Gaps = 68/324 (20%)
Query: 108 KRKVLNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQS 167
KR L+ ++I + LG G+ G V LAR+ + +VA+K++ + + + QS
Sbjct: 24 KRWTLSDFDIGKPLGRGKFGHVYLAREKRSNHVVALKVLFKSQLQ-------------QS 70
Query: 168 GIEDEKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETK 227
+E + ++RE+ I H ++++L D K ++YL+LEY ++GE+ D+ + K
Sbjct: 71 QVEHQ-LRREVEIQSHLRHPNILRLYGYFYDQK--RVYLILEYAARGELY---KDLQKCK 124
Query: 228 ARGPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXXXX 287
S +R + L Y H + +IHRDIKP NLL+ G +KI+DFG
Sbjct: 125 -----YFSERRAATYVASLARALIYCHGKHVIHRDIKPENLLIGAQGELKIADFG----- 174
Query: 288 XXXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGI 347
GT + PE+ ++ + D + DIW++GI
Sbjct: 175 -----WSVHTFNRRRTMCGTLDYLPPEM------VESVEHDAS---------VDIWSLGI 214
Query: 348 TLHCLLFGMLPFISDYELELFDKIVNEPLVFEPYQKIEQCQ---VSQVECKEEYEEAQXX 404
+ L+G+ PF + + + +IV L F P I +SQ+ KE +
Sbjct: 215 LCYEFLYGVPPFEAMEHSDTYRRIVQVDLKFPPKPIISASAKDLISQMLVKESSQ----- 269
Query: 405 XXXXXXXXXXXRMAIQDAKKHPWV 428
R+ + +HPW+
Sbjct: 270 -----------RLPLHKLLEHPWI 282
>At1g48490 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 1244
Score = 94.4 bits (233), Expect = 9e-19
Identities = 81/309 (26%), Positives = 127/309 (40%), Gaps = 59/309 (19%)
Query: 92 PVKETNTVSLEYDPISKRK--VLNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRH 149
P+++ SL P+ R ++ +E+++ + G G V LAR T L AIK++ +
Sbjct: 803 PLEDDVVRSLRTSPVHLRDRISIDDFEVMKSISRGAFGHVILARKNTTGDLFAIKVLRKA 862
Query: 150 KKRTFNDKFSNRFKTPQSGIEDEKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLE 209
N +E +R+I I + VV+ S +YLV+E
Sbjct: 863 DMIRKN------------AVESILAERDILI--NARNPFVVRFFYSF--TCSENLYLVME 906
Query: 210 YCSKGEIKWCPGDVIETKARGPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLL 269
Y + G+ + R L R V+L LEYLH +G++HRD+KP NLL
Sbjct: 907 YLNGGDFY--------SMLRKIGCLDEANARVYIAEVVLALEYLHSEGVVHRDLKPDNLL 958
Query: 270 LSEDGIVKISDFGVXXXXXXXXXXXXXXXXXXA------------------KTAGTPAFF 311
++ DG VK++DFG+ A GTP +
Sbjct: 959 IAHDGHVKLTDFGLSKVGLINNTDDLSGPVSSATSLLVEEKPKLPTLDHKRSAVGTPDYL 1018
Query: 312 APEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGITLHCLLFGMLPFISDYELELFDKI 371
APEI L D W++GI L+ L G+ PF +D+ ++FD I
Sbjct: 1019 APEILLGTGH---------------GATADWWSVGIILYEFLVGIPPFNADHPQQIFDNI 1063
Query: 372 VNEPLVFEP 380
+N + + P
Sbjct: 1064 LNRNIQWPP 1072
>7302511 [T] KOG0576 Mitogen-activated protein kinase kinase kinase kinase
(MAP4K) germinal center kinase family
Length = 1218
Score = 94.4 bits (233), Expect = 9e-19
Identities = 72/243 (29%), Positives = 114/243 (46%), Gaps = 46/243 (18%)
Query: 106 ISKRKVLNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTP 165
IS+R + YE+I+++G G +G V A+ + + +L AIK++ P
Sbjct: 17 ISRRNPQDEYELIQKIGSGTYGDVYKAKRIQSNELAAIKVIKLE---------------P 61
Query: 166 QSGIEDEKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIE 225
I+ I++EI +M+ C H +++ + K+++ +E+C G ++ D+ +
Sbjct: 62 SDDIQI--IQQEIIMMRDCRHPNIIAYYGSY--LRRDKLWICMEFCGGGSLQ----DIYQ 113
Query: 226 TKARGPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXX 285
PL Q + R L GLEYLH G +HRDIK AN+LL+E G VK++DFGV
Sbjct: 114 VTG---PLTEVQ-IAYMCRETLKGLEYLHSMGKMHRDIKGANILLTEYGDVKLADFGVSA 169
Query: 286 XXXXXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAM 345
GTP + APE+ VE ++ + DIWA
Sbjct: 170 QITATINKRKSF-------IGTPYWMAPEVAAVE------------RKGGYNQLCDIWAC 210
Query: 346 GIT 348
GIT
Sbjct: 211 GIT 213
>Hs7657214 [T] KOG0583 Serine/threonine protein kinase
Length = 714
Score = 94.0 bits (232), Expect = 1e-18
Identities = 72/259 (27%), Positives = 123/259 (46%), Gaps = 45/259 (17%)
Query: 120 ELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIEDEKIKREIA 179
+LG G KV+ ++T + VAIK+++ KKR D + + ++RE
Sbjct: 67 KLGEGSFAKVREGLHVLTGEKVAIKVID--KKRAKKDTYVTK-----------NLRREGQ 113
Query: 180 IMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKARGPPLLSFQRT 239
I + H ++ +L+++L+ S YLV+E C PG + K L
Sbjct: 114 IQQMIRHPNITQLLDILETENS--YYLVMELC--------PGGNLMHKIYEKKRLEESEA 163
Query: 240 REIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXXXXXXXXXXXXXXXX 299
R R ++ +E+LH G++HRD+K NLLL ED +K+ DFG+
Sbjct: 164 RRYIRQLISAVEHLHRAGVVHRDLKIENLLLDEDNNIKLIDFGL-----SNCAGILGYSD 218
Query: 300 XXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGITLHCLLFGMLPF 359
+ G+PA+ APE+ KK+ P I D+W++G+ ++ +L G LPF
Sbjct: 219 PFSTQCGSPAYAAPELL----ARKKYG-------PKI----DVWSIGVNMYAMLTGTLPF 263
Query: 360 -ISDYELE-LFDKIVNEPL 376
+ + L L+ K+V++ +
Sbjct: 264 TVEPFSLRALYQKMVDKEM 282
>Hs4502553 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 370
Score = 94.0 bits (232), Expect = 1e-18
Identities = 93/357 (26%), Positives = 149/357 (41%), Gaps = 80/357 (22%)
Query: 111 VLNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIE 170
+ + Y+ + LG G +V LA D T++LVAIK + K K
Sbjct: 16 IRDIYDFRDVLGTGAFSEVILAEDKRTQKLVAIKCI---AKEALEGK------------- 59
Query: 171 DEKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKARG 230
+ ++ EIA++ K H ++V L ++ + +YL+++ S GE+ D I K
Sbjct: 60 EGSMENEIAVLHKIKHPNIVALDDIYESGGH--LYLIMQLVSGGELF----DRIVEKGF- 112
Query: 231 PPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLL---LSEDGIVKISDFGVXXXX 287
+R IF+ VL ++YLH GI+HRD+KP NLL L ED + ISDFG+
Sbjct: 113 --YTERDASRLIFQ-VLDAVKYLHDLGIVHRDLKPENLLYYSLDEDSKIMISDFGL---- 165
Query: 288 XXXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGI 347
+ GTP + APE+ + P SK D W++G+
Sbjct: 166 ----SKMEDPGSVLSTACGTPGYVAPEVLAQK---------PYSK------AVDCWSIGV 206
Query: 348 TLHCLLFGMLPFISDYELELFDKIVNEPLVFE-PYQKIEQCQVSQVECKEEYEEAQXXXX 406
+ LL G PF + + +LF++I+ F+ PY + + A+
Sbjct: 207 IAYILLCGYPPFYDENDAKLFEQILKAEYEFDSPY------------WDDISDSAKDFIR 254
Query: 407 XXXXXXXXXRMAIQDAKKHPWVCWDFNHNDYMSDQEKSLKLIEQSNFHRSPSEQVEQ 463
R + A +HPW+ D N H+S SEQ+++
Sbjct: 255 HLMEKDPEKRFTCEQALQHPWIAGD---------------TALDKNIHQSVSEQIKK 296
>At3g10540 [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 483
Score = 94.0 bits (232), Expect = 1e-18
Identities = 84/306 (27%), Positives = 134/306 (43%), Gaps = 49/306 (16%)
Query: 76 TVLGSHLNSGQRITYGPVKETNTVSLEYDPISKRKVLNTYEIIEELGHGQHGKVKLARDL 135
T+ G+ ++G+ I+ + S + + + +E+ + G G + KV A+
Sbjct: 10 TLQGNSSSNGETIS-------RSKSFAFKAPQENFTYHDFELGKIYGVGSYSKVVRAKKK 62
Query: 136 VTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIEDEKIKREIAIMKKCHHEHVVKLIEV 195
+ A+KI+++ +F T ++ + +K E ++ + H +VKL
Sbjct: 63 DNGTVYALKIMDK------------KFITKEN--KTAYVKLERIVLDQLEHPGIVKLFFT 108
Query: 196 LDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKARGPPLLSFQRTREIFRGVLLGLEYLHF 255
D +S +Y+ LE C GE+ D I K R LS R V+ LEY+H
Sbjct: 109 FQDTQS--LYMALESCEGGELF----DQITRKGR----LSEDEARFYSAEVVDALEYIHN 158
Query: 256 QGIIHRDIKPANLLLSEDGIVKISDFGVXXXXXXXXXXXXXXXXXXAKT---AGTPAFFA 312
G+IHRDIKP NLLL+ DG +KI+DFG K GT A+
Sbjct: 159 MGLIHRDIKPENLLLTLDGHIKIADFGSVKPMQDSQITVLPNAASDDKACTFVGTAAYVP 218
Query: 313 PEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGITLHCLLFGMLPFISDYELELFDKIV 372
PE+ NS +F D+WA+G TL+ +L G PF E +F +I+
Sbjct: 219 PEVL-------------NSSP--ATFGNDLWALGCTLYQMLSGTSPFKDASEWLIFQRII 263
Query: 373 NEPLVF 378
+ F
Sbjct: 264 ARDIKF 269
>At2g45490 [D] KOG0580 Serine/threonine protein kinase
Length = 288
Score = 94.0 bits (232), Expect = 1e-18
Identities = 79/321 (24%), Positives = 136/321 (41%), Gaps = 62/321 (19%)
Query: 108 KRKVLNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQS 167
K+ L +EI LG G+ G+V LAR+ +K +VA+K++ + + +
Sbjct: 15 KQWSLADFEIGRPLGKGKFGRVYLAREAKSKYIVALKVIFKEQIEKYKIH---------- 64
Query: 168 GIEDEKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETK 227
+++RE+ I H ++++L D + +I+L+LEY GE+ V++
Sbjct: 65 ----HQLRREMEIQTSLRHPNILRLFGWFHD--NERIFLILEYAHGGELY----GVLKQN 114
Query: 228 ARGPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXXXX 287
L+ Q+ + L Y H + +IHRDIKP NLLL +G +KI+DFG
Sbjct: 115 GH----LTEQQAATYIASLSQALAYCHGKCVIHRDIKPENLLLDHEGRLKIADFG----- 165
Query: 288 XXXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGI 347
GT + APE+ ++ D D + D W +GI
Sbjct: 166 -----WSVQSSNKRKTMCGTLDYLAPEM------VENRDHD---------YAVDNWTLGI 205
Query: 348 TLHCLLFGMLPFISDYELELFDKIVNEPLVFEPYQKIEQCQVSQVECKEEYEEAQXXXXX 407
+ L+G PF ++ + + F +I+ L F + EEA+
Sbjct: 206 LCYEFLYGNPPFEAESQKDTFKRILKIDLSFPLTPNVS-------------EEAKNLISQ 252
Query: 408 XXXXXXXXRMAIQDAKKHPWV 428
R++I+ +HPW+
Sbjct: 253 LLVKDPSKRLSIEKIMQHPWI 273
>At2g25880 [D] KOG0580 Serine/threonine protein kinase
Length = 282
Score = 94.0 bits (232), Expect = 1e-18
Identities = 81/324 (25%), Positives = 140/324 (43%), Gaps = 68/324 (20%)
Query: 108 KRKVLNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQS 167
KR + ++I + LG G+ G V LAR+ + +VA+K++ + + + QS
Sbjct: 12 KRWTTSDFDIGKPLGRGKFGHVYLAREKRSDHIVALKVLFKAQLQ-------------QS 58
Query: 168 GIEDEKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETK 227
+E + ++RE+ I H ++++L D K ++YL+LEY +GE+ +
Sbjct: 59 QVEHQ-LRREVEIQSHLRHPNILRLYGYFYDQK--RVYLILEYAVRGELY--------KE 107
Query: 228 ARGPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXXXX 287
+ S +R + L Y H + +IHRDIKP NLL+ G +KI+DFG
Sbjct: 108 LQKCKYFSERRAATYVASLARALIYCHGKHVIHRDIKPENLLIGAQGELKIADFG----- 162
Query: 288 XXXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGI 347
GT + PE+ ++ + D + DIW++GI
Sbjct: 163 -----WSVHTFNRRRTMCGTLDYLPPEM------VESVEHDAS---------VDIWSLGI 202
Query: 348 TLHCLLFGMLPFISDYELELFDKIVNEPLVFEPYQKIEQCQ---VSQVECKEEYEEAQXX 404
+ L+G+ PF + E + +IV L F P + +SQ+ KE +
Sbjct: 203 LCYEFLYGVPPFEAREHSETYKRIVQVDLKFPPKPIVSSSAKDLISQMLVKESTQ----- 257
Query: 405 XXXXXXXXXXXRMAIQDAKKHPWV 428
R+A+ +HPW+
Sbjct: 258 -----------RLALHKLLEHPWI 270
>Hs6005850 [D] KOG0615 Serine/threonine protein kinase Chk2 and related
proteins
Length = 543
Score = 93.6 bits (231), Expect = 1e-18
Identities = 90/334 (26%), Positives = 140/334 (40%), Gaps = 55/334 (16%)
Query: 99 VSLEYDPISKRKVLNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKF 158
++++ + + + + Y + + LG G G+VKLA + T + VAIKI+++ K
Sbjct: 204 LTVDDQSVYPKALRDEYIMSKTLGSGACGEVKLAFERKTCKKVAIKIISKRKFAIG---- 259
Query: 159 SNRFKTPQSGIEDEKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKW 218
S R P +E E I I+KK +H ++K+ D + Y+VLE GE+
Sbjct: 260 SAREADPALNVETE-----IEILKKLNHPCIIKIKNFFD---AEDYYIVLELMEGGELF- 310
Query: 219 CPGDVIETKARGPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLS---EDGI 275
K G L + F +LL ++YLH GIIHRD+KP N+LLS ED +
Sbjct: 311 -------DKVVGNKRLKEATCKLYFYQMLLAVQYLHENGIIHRDLKPENVLLSSQEEDCL 363
Query: 276 VKISDFGVXXXXXXXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPI 335
+KI+DFG GTP + APE+ + T
Sbjct: 364 IKITDFG--------HSKILGETSLMRTLCGTPTYLAPEVLVSVGTAG------------ 403
Query: 336 ISFPTDIWAMGITLHCLLFGMLPFISD-YELELFDKIVNEPLVFEPYQKIEQCQVSQVEC 394
+ D W++G+ L L G PF ++ L D+I + F P
Sbjct: 404 YNRAVDCWSLGVILFICLSGYPPFSEHRTQVSLKDQITSGKYNFIP-----------EVW 452
Query: 395 KEEYEEAQXXXXXXXXXXXXXRMAIQDAKKHPWV 428
E E+A R ++A +HPW+
Sbjct: 453 AEVSEKALDLVKKLLVVDPKARFTTEEALRHPWL 486
>Hs14196445 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 476
Score = 93.6 bits (231), Expect = 1e-18
Identities = 92/353 (26%), Positives = 149/353 (42%), Gaps = 68/353 (19%)
Query: 111 VLNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIE 170
+ T+ +E LG G +V L + +T +L A+K + K+P
Sbjct: 19 IRKTFIFMEVLGSGAFSEVFLVKQRLTGKLFALKCIK---------------KSP--AFR 61
Query: 171 DEKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKARG 230
D ++ EIA++KK HE++V L ++ + + YLV++ S GE+ ++E RG
Sbjct: 62 DSSLENEIAVLKKIKHENIVTLEDIYES--TTHYYLVMQLVSGGELF---DRILE---RG 113
Query: 231 PPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLL---SEDGIVKISDFGVXXXX 287
+ + + + + VL ++YLH GI+HRD+KP NLL E+ + I+DFG+
Sbjct: 114 --VYTEKDASLVIQQVLSAVKYLHENGIVHRDLKPENLLYLTPEENSKIMITDFGL---- 167
Query: 288 XXXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGI 347
+ GTP + APE+ + P SK D W++G+
Sbjct: 168 -----SKMEQNGIMSTACGTPGYVAPEVLAQK---------PYSK------AVDCWSIGV 207
Query: 348 TLHCLLFGMLPFISDYELELFDKIVNEPLVFEPYQKIEQCQVSQVECKEEYEEAQXXXXX 407
+ LL G PF + E +LF+KI E Y + E + E A+
Sbjct: 208 ITYILLCGYPPFYEETESKLFEKIK------EGYYEFESPFWDDIS-----ESAKDFICH 256
Query: 408 XXXXXXXXRMAIQDAKKHPWVCWDFNHNDYMSDQEKSLKLIEQSNFHRSPSEQ 460
R + A HPW+ + D S+ L Q NF +S Q
Sbjct: 257 LLEKDPNERYTCEKALSHPWI---DGNTALHRDIYPSVSLQIQKNFAKSKWRQ 306
>CE28273 [T] KOG0587 Traf2- and Nck-interacting kinase and related germinal
center kinase (GCK) family protein kinases
Length = 1096
Score = 93.6 bits (231), Expect = 1e-18
Identities = 77/254 (30%), Positives = 119/254 (46%), Gaps = 48/254 (18%)
Query: 102 EYDPISKRKVLNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNR 161
E D S R +E+IE +G+G +G+V R + T QL AIKI+N ++
Sbjct: 8 EIDLNSLRDPAGIFELIEVVGNGTYGQVYKGRHVKTAQLAAIKIMNINED---------- 57
Query: 162 FKTPQSGIEDEKIKREIAIMKK-CHHEHVVK----LIEVLDDA--KSRKIYLVLEYCSKG 214
E+++IK EI ++KK HH +V I+ L + K +++LV+E+C G
Sbjct: 58 --------EEDEIKLEINMLKKHSHHRNVATYYGAFIKKLPSSTGKHDQLWLVMEFCGSG 109
Query: 215 EIKWCPGDVIETKARGPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDG 274
I D+++ G L + I R +L GL +LH +IHRDIK N+LL++
Sbjct: 110 SIT----DLVKNTKGGS--LKEEWIAYICREILRGLYHLHQSKVIHRDIKGQNVLLTDSA 163
Query: 275 IVKISDFGVXXXXXXXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEP 334
VK+ DFGV GTP + APE+ ++ S E
Sbjct: 164 EVKLVDFGVSAQLDKTVGRRNTF-------IGTPYWMAPEVIACDE----------SPEA 206
Query: 335 IISFPTDIWAMGIT 348
+D+W++GIT
Sbjct: 207 TYDSRSDLWSLGIT 220
>CE25673 [T] KOG0587 Traf2- and Nck-interacting kinase and related germinal
center kinase (GCK) family protein kinases
Length = 1082
Score = 93.6 bits (231), Expect = 1e-18
Identities = 77/254 (30%), Positives = 119/254 (46%), Gaps = 48/254 (18%)
Query: 102 EYDPISKRKVLNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNR 161
E D S R +E+IE +G+G +G+V R + T QL AIKI+N ++
Sbjct: 8 EIDLNSLRDPAGIFELIEVVGNGTYGQVYKGRHVKTAQLAAIKIMNINED---------- 57
Query: 162 FKTPQSGIEDEKIKREIAIMKK-CHHEHVVK----LIEVLDDA--KSRKIYLVLEYCSKG 214
E+++IK EI ++KK HH +V I+ L + K +++LV+E+C G
Sbjct: 58 --------EEDEIKLEINMLKKHSHHRNVATYYGAFIKKLPSSTGKHDQLWLVMEFCGSG 109
Query: 215 EIKWCPGDVIETKARGPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDG 274
I D+++ G L + I R +L GL +LH +IHRDIK N+LL++
Sbjct: 110 SIT----DLVKNTKGGS--LKEEWIAYICREILRGLYHLHQSKVIHRDIKGQNVLLTDSA 163
Query: 275 IVKISDFGVXXXXXXXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEP 334
VK+ DFGV GTP + APE+ ++ S E
Sbjct: 164 EVKLVDFGVSAQLDKTVGRRNTF-------IGTPYWMAPEVIACDE----------SPEA 206
Query: 335 IISFPTDIWAMGIT 348
+D+W++GIT
Sbjct: 207 TYDSRSDLWSLGIT 220
>CE25672 [T] KOG0587 Traf2- and Nck-interacting kinase and related germinal
center kinase (GCK) family protein kinases
Length = 1087
Score = 93.6 bits (231), Expect = 1e-18
Identities = 77/254 (30%), Positives = 119/254 (46%), Gaps = 48/254 (18%)
Query: 102 EYDPISKRKVLNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNR 161
E D S R +E+IE +G+G +G+V R + T QL AIKI+N ++
Sbjct: 8 EIDLNSLRDPAGIFELIEVVGNGTYGQVYKGRHVKTAQLAAIKIMNINED---------- 57
Query: 162 FKTPQSGIEDEKIKREIAIMKK-CHHEHVVK----LIEVLDDA--KSRKIYLVLEYCSKG 214
E+++IK EI ++KK HH +V I+ L + K +++LV+E+C G
Sbjct: 58 --------EEDEIKLEINMLKKHSHHRNVATYYGAFIKKLPSSTGKHDQLWLVMEFCGSG 109
Query: 215 EIKWCPGDVIETKARGPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDG 274
I D+++ G L + I R +L GL +LH +IHRDIK N+LL++
Sbjct: 110 SIT----DLVKNTKGGS--LKEEWIAYICREILRGLYHLHQSKVIHRDIKGQNVLLTDSA 163
Query: 275 IVKISDFGVXXXXXXXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEP 334
VK+ DFGV GTP + APE+ ++ S E
Sbjct: 164 EVKLVDFGVSAQLDKTVGRRNTF-------IGTPYWMAPEVIACDE----------SPEA 206
Query: 335 IISFPTDIWAMGIT 348
+D+W++GIT
Sbjct: 207 TYDSRSDLWSLGIT 220
>At1g60940 [T] KOG0583 Serine/threonine protein kinase
Length = 361
Score = 93.6 bits (231), Expect = 1e-18
Identities = 93/385 (24%), Positives = 157/385 (40%), Gaps = 80/385 (20%)
Query: 112 LNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIED 171
++ YE+++++G G G +L R +K+LVA+K + R K D
Sbjct: 1 MDKYELVKDIGAGNFGVARLMRVKNSKELVAMKYIERGPK------------------ID 42
Query: 172 EKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKARGP 231
E + REI + H ++++ EV+ I + +EY + GE+ + I + R
Sbjct: 43 ENVAREIINHRSLRHPNIIRFKEVV--LTPTHIAIAMEYAAGGEL----FERICSAGR-- 94
Query: 232 PLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLL--SEDGIVKISDFGVXXXXXX 289
S R F+ ++ G+ Y H I HRD+K N LL S +KI DFG
Sbjct: 95 --FSEDEARYFFQQLISGVSYCHAMQICHRDLKLENTLLDGSPAPRLKICDFG------- 145
Query: 290 XXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGITL 349
T GTPA+ APE+ + + + D D+W+ G+TL
Sbjct: 146 -YSKSSLLHSMPKSTVGTPAYIAPEV------LSRGEYDGKM--------ADVWSCGVTL 190
Query: 350 HCLLFGMLPFISDYELELFDKIVNEPLVFEPYQKIEQCQVSQVECKEEYEEAQXXXXXXX 409
+ +L G PF + + F K + + + Y+ + +SQ +CK
Sbjct: 191 YVMLVGAYPFEDQEDPKNFKKTIQRIMAVK-YKIPDYVHISQ-DCKH-------LLSRIF 241
Query: 410 XXXXXXRMAIQDAKKHPWVCWDFNHNDYMSDQEKSLKLIEQSNFHRSPS-----EQVEQI 464
R+ I D KKHPW ++ + + L I Q+ + R + + VE+I
Sbjct: 242 VTNSNKRITIGDIKKHPW---------FLKNLPRELTEIAQAAYFRKENPTFSLQSVEEI 292
Query: 465 CISEHEVDTAVGGIGHKIKNAVGKF 489
E T ++ ++G F
Sbjct: 293 MKIVEEAKTPA-----RVSRSIGAF 312
>At1g50230 [R] KOG0597 Serine-threonine protein kinase FUSED
Length = 269
Score = 93.6 bits (231), Expect = 1e-18
Identities = 68/264 (25%), Positives = 118/264 (43%), Gaps = 48/264 (18%)
Query: 115 YEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIEDEKI 174
Y +IE +G G G+V R T Q VA+K + + K DK + +
Sbjct: 6 YHVIELVGEGSFGRVYKGRRKYTGQTVAMKFIMKQGK---TDK------------DIHSL 50
Query: 175 KREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKARGPPLL 234
++EI I++K HE+++++++ ++A+ E+C E + G++ E L
Sbjct: 51 RQEIEILRKLKHENIIEMLDSFENAR--------EFCVVTE--FAQGELFEI-LEDDKCL 99
Query: 235 SFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXXXXXXXXXXX 294
++ + I + ++ L+YLH IIHRD+KP N+L+ +VK+ DFG
Sbjct: 100 PEEQVQAIAKQLVKALDYLHSNRIIHRDMKPQNILIGAGSVVKLCDFG-------FARAM 152
Query: 295 XXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGITLHCLLF 354
GTP + APE+ KE D+W++G+ L+ L
Sbjct: 153 STNTVVLRSIKGTPLYMAPELV---------------KEQPYDRTVDLWSLGVILYELYV 197
Query: 355 GMLPFISDYELELFDKIVNEPLVF 378
G PF ++ L IV +P+ +
Sbjct: 198 GQPPFYTNSVYALIRHIVKDPVKY 221
>7290147 [T] KOG0583 Serine/threonine protein kinase
Length = 291
Score = 93.6 bits (231), Expect = 1e-18
Identities = 57/186 (30%), Positives = 91/186 (48%), Gaps = 28/186 (15%)
Query: 174 IKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKARGPPL 233
IK E+ I+ + H H+V+ + A + + +V+EY G ++ DVI+ G
Sbjct: 55 IKEEVYIISQLRHPHIVEFLRSFSHAGT--VNIVMEYVPNGTLR----DVIQQLPSGTGG 108
Query: 234 LSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXXXXXXXXXX 293
++ +R FR +++GLEYLH + +IHRDIKP N+LL + VKI+DFG+
Sbjct: 109 VNQERLMGYFRDMVVGLEYLHIRCVIHRDIKPENMLLDANDRVKIADFGIANVHAPSTQL 168
Query: 294 XXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGITLHCLL 353
GTP + APE S + + F +D+W++G+ L+ L
Sbjct: 169 QAG--------MGTPMYMAPEAM--------------SSQGKVDFKSDVWSLGLVLYELC 206
Query: 354 FGMLPF 359
G PF
Sbjct: 207 LGRSPF 212
>Hs7661994 [T] KOG0579 Ste20-like serine/threonine protein kinase
Length = 1152
Score = 93.2 bits (230), Expect = 2e-18
Identities = 65/235 (27%), Positives = 106/235 (44%), Gaps = 43/235 (18%)
Query: 115 YEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIEDEKI 174
+EII ELG G GKV A++ T L A K+++ + D
Sbjct: 34 WEIIGELGDGAFGKVYKAQNKETSVLAAAKVIDTKSEEELEDYMV--------------- 78
Query: 175 KREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKARGPPLL 234
EI I+ C H ++VKL++ +++++E+C+ G + D + + P L
Sbjct: 79 --EIDILASCDHPNIVKLLDAF--YYENNLWILIEFCAGGAV-----DAVMLELERP--L 127
Query: 235 SFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXXXXXXXXXXX 294
+ + + + + L L YLH IIHRD+K N+L + DG +K++DFGV
Sbjct: 128 TESQIQVVCKQTLDALNYLHDNKIIHRDLKAGNILFTLDGDIKLADFGVSAKNTRTIQRR 187
Query: 295 XXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGITL 349
GTP + APE+ + E SK+ + D+W++GITL
Sbjct: 188 DSF-------IGTPYWMAPEVVMCE----------TSKDRPYDYKADVWSLGITL 225
>Hs4759178 [D] KOG0580 Serine/threonine protein kinase
Length = 344
Score = 93.2 bits (230), Expect = 2e-18
Identities = 82/280 (29%), Positives = 126/280 (44%), Gaps = 58/280 (20%)
Query: 104 DPISKRKVLNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFK 163
D +++ ++ +EI LG G+ G V LAR+ + +VA+K++ F ++ +
Sbjct: 66 DILTRHFTIDDFEIGRPLGKGKFGNVYLAREKKSHFIVALKVL-----------FKSQIE 114
Query: 164 TPQSGIEDEKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEI-----KW 218
+ G+E + ++REI I HH ++++L D R+IYL+LEY +GE+ K
Sbjct: 115 --KEGVEHQ-LRREIEIQAHLHHPNILRLYNYFYDR--RRIYLILEYAPRGELYKELQKS 169
Query: 219 CPGDVIETKARGPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKI 278
C D QRT I + L Y H + +IHRDIKP NLLL G +KI
Sbjct: 170 CTFDE-------------QRTATIMEELADALMYCHGKKVIHRDIKPENLLLGLKGELKI 216
Query: 279 SDFGVXXXXXXXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISF 338
+DFG GT + PE ++E + N K
Sbjct: 217 ADFG---------WSVHAPSLRRKTMCGTLDYLPPE--MIEGRMH------NEK------ 253
Query: 339 PTDIWAMGITLHCLLFGMLPFISDYELELFDKIVNEPLVF 378
D+W +G+ + LL G PF S E + +IV L F
Sbjct: 254 -VDLWCIGVLCYELLVGNPPFESASHNETYRRIVKVDLKF 292
>At5g66880 [T] KOG0583 Serine/threonine protein kinase
Length = 361
Score = 93.2 bits (230), Expect = 2e-18
Identities = 81/315 (25%), Positives = 127/315 (39%), Gaps = 61/315 (19%)
Query: 115 YEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIEDEKI 174
Y+ ++++G G G +L RD +TK+LVA+K + R DK DE +
Sbjct: 22 YDFVKDIGSGNFGVARLMRDKLTKELVAVKYIER------GDKI------------DENV 63
Query: 175 KREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKARGPPLL 234
+REI + H ++V+ EV+ + +++EY S GE + +
Sbjct: 64 QREIINHRSLRHPNIVRFKEVI--LTPTHLAIIMEYASGGE--------LYERICNAGRF 113
Query: 235 SFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLL--SEDGIVKISDFGVXXXXXXXXX 292
S R F+ +L G+ Y H I HRD+K N LL S +KI DFG
Sbjct: 114 SEDEARFFFQQLLSGVSYCHSMQICHRDLKLENTLLDGSPAPRLKICDFG--------YS 165
Query: 293 XXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGITLHCL 352
T GTPA+ APE+ L ++ K D+W+ G+TL+ +
Sbjct: 166 KSSVLHSQPKSTVGTPAYIAPEVLLRQEYDGKI--------------ADVWSCGVTLYVM 211
Query: 353 LFGMLPFISDYELELFDKIVNEPLVFEPYQKIEQCQVSQVECKEEYEEAQXXXXXXXXXX 412
L G PF E + K + L + Y + ++S C
Sbjct: 212 LVGAYPFEDPEEPRDYRKTIQRILSVK-YSIPDDIRISPECC--------HLISRIFVAD 262
Query: 413 XXXRMAIQDAKKHPW 427
R++I + K H W
Sbjct: 263 PATRISIPEIKTHSW 277
>CE16081 [T] KOG0583 Serine/threonine protein kinase
Length = 334
Score = 92.8 bits (229), Expect = 2e-18
Identities = 69/245 (28%), Positives = 112/245 (45%), Gaps = 47/245 (19%)
Query: 115 YEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIEDEKI 174
Y + +ELG G KVKL +TK+ VA+KI+++ K K +
Sbjct: 49 YRLGKELGAGNFSKVKLGVHQLTKEKVAVKIMDKAKMDAKAQKL---------------L 93
Query: 175 KREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKARGPPLL 234
REI M++ +H ++VKL EV++ +++LV+EY S GE+ T L
Sbjct: 94 SREIQAMEEMNHPNIVKLFEVVETLT--RVHLVIEYASGGELY--------TYVHERGKL 143
Query: 235 SFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXXXXXXXXXXX 294
+ + +F ++ + ++H + I+HRDIK N++ S VK+ DFG
Sbjct: 144 TEGDAKPLFAQIVSAVSHMHSRNIVHRDIKAENVMFSSPNTVKLVDFGFSCLVDREQMLR 203
Query: 295 XXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGITLHCLLF 354
G+P + APE L +DT +L D+WA+G+ L +L
Sbjct: 204 TF--------CGSPPYAAPE--LFQDTSYAGEL------------VDVWALGVLLFFMLI 241
Query: 355 GMLPF 359
G+ PF
Sbjct: 242 GVTPF 246
>YCR091w [R] KOG0610 Putative serine/threonine protein kinase
Length = 720
Score = 92.4 bits (228), Expect = 3e-18
Identities = 98/380 (25%), Positives = 152/380 (39%), Gaps = 57/380 (15%)
Query: 114 TYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIEDEK 173
++E I LG G GKV L R+ T Q+ A+K++N+H+ I+ +K
Sbjct: 323 SFEKIRLLGQGDVGKVYLMRERDTNQIFALKVLNKHEM-----------------IKRKK 365
Query: 174 IKR---EIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKARG 230
IKR E I+ H +V L +YL +EYC GE + R
Sbjct: 366 IKRVLTEQEILATSDHPFIVTLYHSFQTKDY--LYLCMEYCMGGEF------FRALQTRK 417
Query: 231 PPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXXXXXXX 290
++ + + V+ LEYLH G I+RD+KP N+LL + G V +SDF +
Sbjct: 418 SKCIAEEDAKFYASEVVAALEYLHLLGFIYRDLKPENILLHQSGHVMLSDFDLSIQATGS 477
Query: 291 XXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGITLH 350
+ F E+ + + N + D W +GI ++
Sbjct: 478 KKPTMKDSTYLDTKICSDGFRTNSFVGTEEYLAPEVIRGNGHTAAV----DWWTLGILIY 533
Query: 351 CLLFGMLPFISDYELELFDKIVNEPLVFEPYQKIEQCQVSQVECKEEYEEAQXXXXXXXX 410
+LFG PF D E F I+ + + F P+ K +VS+ CK+ ++
Sbjct: 534 EMLFGCTPFKGDNSNETFSNILTKDVKF-PHDK----EVSK-NCKDLIKK---LLNKNEA 584
Query: 411 XXXXXRMAIQDAKKHPW---VCWDFNHND------YMSDQEKSLKLIEQSNFH---RSPS 458
+ D K+HP+ V W F N ++D L I N H S S
Sbjct: 585 KRLGSKSGAADIKRHPFFKKVQWSFLRNQDPPLIPALNDNGCELPFILSCNKHPKRNSVS 644
Query: 459 EQ-VEQIC---ISEHEVDTA 474
EQ + C ++ E+D A
Sbjct: 645 EQETKMFCEKVANDDEIDEA 664
>At1g12580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 522
Score = 92.4 bits (228), Expect = 3e-18
Identities = 78/287 (27%), Positives = 134/287 (46%), Gaps = 54/287 (18%)
Query: 104 DPISKRKVLNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFK 163
+P++ + + Y + E+LG GQ G +++ D +T + +A K +++ + T +D S
Sbjct: 33 NPVNVSNLKDRYVLGEQLGWGQFGVIRVCSDKLTGERLACKSISKDRLVTQDDMKS---- 88
Query: 164 TPQSGIEDEKIKREIAIMKK-CHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGD 222
IK EIAIM K H +VV L V ++ S ++LV+E C+ GE+
Sbjct: 89 ----------IKLEIAIMAKLAGHPNVVNLKAVYEEKDS--VHLVMELCAGGELF----H 132
Query: 223 VIETKARGPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLL---LSEDGIVKIS 279
+E R S R R +F+ ++ +++ H GI+HRD+KP N+L +S +K++
Sbjct: 133 KLEKYGR----YSEVRARVLFKHLMQVVKFCHDSGIVHRDLKPENILMATMSSSSPIKLA 188
Query: 280 DFGVXXXXXXXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFP 339
DFG+ + T G+P + APE+ +
Sbjct: 189 DFGL--------ATYIKPGEKLSGTVGSPFYIAPEVLAGG----------------YNQA 224
Query: 340 TDIWAMGITLHCLLFGMLPFISDYELELFDKIVNEPLVF--EPYQKI 384
D+W+ G+ L+ LL G PF + ++FD + L F EP+ I
Sbjct: 225 ADVWSAGVILYILLSGAPPFWGKTKSKIFDAVRAADLRFSAEPWDNI 271
>YKL166c [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 398
Score = 92.0 bits (227), Expect = 4e-18
Identities = 79/335 (23%), Positives = 139/335 (40%), Gaps = 64/335 (19%)
Query: 101 LEYDPISKRKVLNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSN 160
L+Y S + L+ ++I+ LG G G+V L R + A+K + +H
Sbjct: 74 LQYRDTSGKYSLSDFQILRTLGTGSFGRVHLIRSNHNGRFYALKTLKKH----------- 122
Query: 161 RFKTPQSGIEDEKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCP 220
T + E E ++ H ++++ D S+++++V++Y GE+
Sbjct: 123 ---TIVKLKQVEHTNDERRMLSIVSHPFIIRMWGTFQD--SQQVFMVMDYIEGGELF--- 174
Query: 221 GDVIETKARGP-PLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKIS 279
++ R P P+ F V L LEYLH + II+RD+KP N+LL ++G +KI+
Sbjct: 175 -SLLRKSQRFPNPVAKFYAAE-----VCLALEYLHSKDIIYRDLKPENILLDKNGHIKIT 228
Query: 280 DFGVXXXXXXXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFP 339
DFG GTP + APE+ + P +K
Sbjct: 229 DFGFAKYVPDVTYT----------LCGTPDYIAPEVVSTK---------PYNKS------ 263
Query: 340 TDIWAMGITLHCLLFGMLPFISDYELELFDKIVNEPLVFEPYQKIEQCQVSQVECKEEYE 399
D W+ G+ ++ +L G PF + ++ ++ I+N L F P+ + + + +
Sbjct: 264 VDWWSFGVLIYEMLAGYTPFYNSNTMKTYENILNAELKFPPFFHPDAQDLLKKLITRDLS 323
Query: 400 EAQXXXXXXXXXXXXXRMAIQDAKKHPW---VCWD 431
E + +D K HPW V W+
Sbjct: 324 E----------RLGNLQNGSEDVKNHPWFNEVIWE 348
>YDR523c [T] KOG0201 Serine/threonine protein kinase
Length = 490
Score = 92.0 bits (227), Expect = 4e-18
Identities = 79/252 (31%), Positives = 115/252 (45%), Gaps = 50/252 (19%)
Query: 115 YEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIEDEKI 174
Y I +G G G V A D VT+++VAIK+VN S + E +
Sbjct: 18 YSIQSCIGRGNFGDVYKAVDRVTQEIVAIKVVNLE----------------HSDEDIELL 61
Query: 175 KREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKARGPPLL 234
+EI + + + I + + S +++V+EYC G C + + G P
Sbjct: 62 AQEIFFLAELKSPLITNYIATMLEDVS--MWIVMEYCGGGS---CSDLLKRSYVNGLPE- 115
Query: 235 SFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXXXXXXXXXXX 294
++ I V LGL+YLH Q IHRDIK AN+LL+E+G+VK+ DFGV
Sbjct: 116 --EKVSFIIHEVTLGLKYLHEQRKIHRDIKAANILLNEEGMVKLGDFGVSGHIRSTLKRD 173
Query: 295 XXXXXXXAKTAGTPAFFAPEI--CLVEDTIKKFDLDPNSKEPIISFPTDIWAMGITLHCL 352
GTP + APE+ C V+ +K DIW++GIT + L
Sbjct: 174 TF--------VGTPYWMAPEVVCCEVDGYNEK---------------ADIWSLGITTYEL 210
Query: 353 LFGMLPFISDYE 364
L G LP +S Y+
Sbjct: 211 LKG-LPPLSKYD 221
>Hs14141724 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 499
Score = 92.0 bits (227), Expect = 4e-18
Identities = 82/318 (25%), Positives = 130/318 (40%), Gaps = 61/318 (19%)
Query: 115 YEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIEDEKI 174
Y++ EELG G V+ + T Q A KI+N K S + +K+
Sbjct: 14 YQLFEELGKGAFSVVRRCMKIPTGQGYAAKIINTKKL---------------SARDHQKL 58
Query: 175 KREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKARGPPLL 234
+RE I + H ++V+L + + + YLV + + GE+ D++ +
Sbjct: 59 EREARICRLLKHPNIVRLHDSISEEGFH--YLVFDLVTGGELF---EDIVARE-----YY 108
Query: 235 SFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLL---SEDGIVKISDFGVXXXXXXXX 291
S + +L + + H GI+HRD+KP NLLL S+ VK++DFG+
Sbjct: 109 SEADASHCIQQILESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQ 168
Query: 292 XXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGITLHC 351
AGTP + +PE+ ++K DP K P D+WA G+ L+
Sbjct: 169 QAWFGF-------AGTPGYLSPEV------LRK---DPYGK------PVDMWACGVILYI 206
Query: 352 LLFGMLPFISDYELELFDKIVNEPLVFEPYQKIEQCQVSQVECKEEYEEAQXXXXXXXXX 411
LL G PF + + L+ +I K E EA+
Sbjct: 207 LLVGYPPFWDEDQHRLYQQI-----------KAGAYDFPSPEWDTVTPEAKDLINKMLTI 255
Query: 412 XXXXRMAIQDAKKHPWVC 429
R+ +A KHPW+C
Sbjct: 256 NPAKRITASEALKHPWIC 273
>CE28059 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 350
Score = 92.0 bits (227), Expect = 4e-18
Identities = 100/409 (24%), Positives = 163/409 (39%), Gaps = 72/409 (17%)
Query: 110 KVLNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGI 169
K + Y++ EELG G V+ T A KI+N K S
Sbjct: 7 KFSDNYDVKEELGKGAFSVVRRCVHKTTGLEFAAKIINTKKL---------------SAR 51
Query: 170 EDEKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKAR 229
+ +K++RE I +K H ++V+L + + + YLV + + GE+ D++ +
Sbjct: 52 DFQKLEREARICRKLQHPNIVRLHDSIQEESFH--YLVFDLVTGGELF---EDIVARE-- 104
Query: 230 GPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLL---SEDGIVKISDFGVXXX 286
S + +L + Y H GI+HRD+KP NLLL ++ VK++DFG+
Sbjct: 105 ---FYSEADASHCIQQILESIAYCHSNGIVHRDLKPENLLLASKAKGAAVKLADFGLAIE 161
Query: 287 XXXXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMG 346
AGTP + +PE+ +KK DP SK P DIWA G
Sbjct: 162 VNDSEAWHGF--------AGTPGYLSPEV------LKK---DPYSK------PVDIWACG 198
Query: 347 ITLHCLLFGMLPFISDYELELFDKIVNEPLVFEPYQKIEQCQVSQVECKEEYEEAQXXXX 406
+ L+ LL G PF + + L+ +I K E EA+
Sbjct: 199 VILYILLVGYPPFWDEDQHRLYAQI-----------KAGAYDYPSPEWDTVTPEAKSLID 247
Query: 407 XXXXXXXXXRMAIQDAKKHPWVCWDFNHNDYMS--DQEKSLKLIEQSNFHRSPSEQVEQI 464
R+ A K PW+C N S ++ ++ +++ N R +
Sbjct: 248 SMLTVNPKKRITADQALKVPWIC---NRERVASAIHRQDTVDCLKKFNARRKLKGAILTT 304
Query: 465 CISEHEVDTAVGGIGHKIKNAVGKFLPST-KSNDESNTNSVNEFNDSGN 512
I+ + +G + N + PST K + ES+ + ++ GN
Sbjct: 305 MIATRN----LSNLGRNLLNKKEQGPPSTIKESSESSQTIDDNDSEKGN 349
>7294265 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 2139
Score = 92.0 bits (227), Expect = 4e-18
Identities = 75/272 (27%), Positives = 121/272 (43%), Gaps = 47/272 (17%)
Query: 113 NTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIEDE 172
N ++I++ + +G +G V L + T+Q A+K +N++ N + E
Sbjct: 833 NDFDIVKLISNGAYGAVYLVKHKTTRQRFAMKKINKNNLILRN--------------QVE 878
Query: 173 KIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKARGPP 232
++ E I+ + VV + + K + LV+EY G+ G ++ K GP
Sbjct: 879 QVFAERDILSFADNPFVVSMYCSFETKKH--LCLVMEYVEGGDC----GTLL--KNIGP- 929
Query: 233 LLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXXXXXXXXX 292
L R F +L +EYLH GI+HRD+KP NLL++ G +K++DFG+
Sbjct: 930 -LPADMARFYFAETVLAVEYLHSYGIVHRDLKPDNLLITALGHIKLTDFGLSKMGLMSLA 988
Query: 293 XXXXXXXXXAKTA--------GTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWA 344
++T GTP + APE+ L + K P D W+
Sbjct: 989 TNLYEGYIDSETRQFSDKQVYGTPEYIAPEVILRQGYGK---------------PVDWWS 1033
Query: 345 MGITLHCLLFGMLPFISDYELELFDKIVNEPL 376
MGI L+ L G +PF + ELF VN+ +
Sbjct: 1034 MGIILYEFLIGCVPFFGETTEELFAHTVNDDI 1065
>HsM5454174 [T] KOG0201 Serine/threonine protein kinase
Length = 426
Score = 91.7 bits (226), Expect = 6e-18
Identities = 68/231 (29%), Positives = 105/231 (45%), Gaps = 49/231 (21%)
Query: 118 IEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIEDEKIKRE 177
++ +G G G+V D TK++VAIKI++ + E E I++E
Sbjct: 23 LDRIGKGSFGEVYKGIDNHTKEVVAIKIIDLEEAED----------------EIEDIQQE 66
Query: 178 IAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKARGPPLLSFQ 237
I ++ +C ++ + KS K+++++EY G ++ GP ++
Sbjct: 67 ITVLSQCDSPYITRYFGSY--LKSTKLWIIMEYLGGGS-------ALDLLKPGPLEETYI 117
Query: 238 RTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXXXXXXXXXXXXXX 297
T I R +L GL+YLH + IHRDIK AN+LLSE G VK++DFGV
Sbjct: 118 AT--ILREILKGLDYLHSERKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTF 175
Query: 298 XXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGIT 348
GTP + APE+ K+ F DIW++GIT
Sbjct: 176 -------VGTPFWMAPEVI---------------KQSAYDFKADIWSLGIT 204
>Hs21361358 [T] KOG0201 Serine/threonine protein kinase
Length = 426
Score = 91.7 bits (226), Expect = 6e-18
Identities = 68/231 (29%), Positives = 105/231 (45%), Gaps = 49/231 (21%)
Query: 118 IEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIEDEKIKRE 177
++ +G G G+V D TK++VAIKI++ + E E I++E
Sbjct: 23 LDRIGKGSFGEVYKGIDNHTKEVVAIKIIDLEEAED----------------EIEDIQQE 66
Query: 178 IAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKARGPPLLSFQ 237
I ++ +C ++ + KS K+++++EY G ++ GP ++
Sbjct: 67 ITVLSQCDSPYITRYFGSY--LKSTKLWIIMEYLGGGS-------ALDLLKPGPLEETYI 117
Query: 238 RTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXXXXXXXXXXXXXX 297
T I R +L GL+YLH + IHRDIK AN+LLSE G VK++DFGV
Sbjct: 118 AT--ILREILKGLDYLHSERKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTF 175
Query: 298 XXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGIT 348
GTP + APE+ K+ F DIW++GIT
Sbjct: 176 -------VGTPFWMAPEVI---------------KQSAYDFKADIWSLGIT 204
>Hs17455844 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 1139
Score = 91.7 bits (226), Expect = 6e-18
Identities = 77/281 (27%), Positives = 122/281 (43%), Gaps = 48/281 (17%)
Query: 107 SKRKVLNT-YEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTP 165
S+RK + +E I+ + +G +G V L R T+Q AIK +N+ N
Sbjct: 188 SRRKPCESDFETIKLISNGAYGAVYLVRHRDTRQRFAIKKINKQNLILRNQ--------- 238
Query: 166 QSGIEDEKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIE 225
I+ ++R+I + + VV + + R + +V+EY G+
Sbjct: 239 ---IQQVFVERDILTFAE--NPFVVSMFCSFETR--RHLCMVMEYVEGGDCATL------ 285
Query: 226 TKARGPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXX 285
K GP L R F +L LEYLH GI+HRD+KP NLL++ G +K++DFG+
Sbjct: 286 LKNMGP--LPVDMARLYFAETVLALEYLHNYGIVHRDLKPDNLLITSLGHIKLTDFGLSK 343
Query: 286 XXXXXXXX--------XXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIIS 337
+ GTP + APE+ + K
Sbjct: 344 IGLMSMATNLYEGHIEKDAREFIDKQVCGTPEYIAPEVIFRQGYGK-------------- 389
Query: 338 FPTDIWAMGITLHCLLFGMLPFISDYELELFDKIVNEPLVF 378
P D WAMG+ L+ L G +PF D ELF ++V++ +++
Sbjct: 390 -PVDWWAMGVVLYEFLVGCVPFFGDTPEELFGQVVSDEIMW 429
>CE28057 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 520
Score = 91.7 bits (226), Expect = 6e-18
Identities = 98/406 (24%), Positives = 162/406 (39%), Gaps = 72/406 (17%)
Query: 110 KVLNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGI 169
K + Y++ EELG G V+ T A KI+N K S
Sbjct: 7 KFSDNYDVKEELGKGAFSVVRRCVHKTTGLEFAAKIINTKKL---------------SAR 51
Query: 170 EDEKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKAR 229
+ +K++RE I +K H ++V+L + + + YLV + + GE+ D++ +
Sbjct: 52 DFQKLEREARICRKLQHPNIVRLHDSIQEESFH--YLVFDLVTGGELF---EDIVARE-- 104
Query: 230 GPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLL---SEDGIVKISDFGVXXX 286
S + +L + Y H GI+HRD+KP NLLL ++ VK++DFG+
Sbjct: 105 ---FYSEADASHCIQQILESIAYCHSNGIVHRDLKPENLLLASKAKGAAVKLADFGLAIE 161
Query: 287 XXXXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMG 346
AGTP + +PE+ +KK DP SK P DIWA G
Sbjct: 162 VNDSEAWHGF--------AGTPGYLSPEV------LKK---DPYSK------PVDIWACG 198
Query: 347 ITLHCLLFGMLPFISDYELELFDKIVNEPLVFEPYQKIEQCQVSQVECKEEYEEAQXXXX 406
+ L+ LL G PF + + L+ +I K E EA+
Sbjct: 199 VILYILLVGYPPFWDEDQHRLYAQI-----------KAGAYDYPSPEWDTVTPEAKSLID 247
Query: 407 XXXXXXXXXRMAIQDAKKHPWVCWDFNHNDYMS--DQEKSLKLIEQSNFHRSPSEQVEQI 464
R+ A K PW+C N S ++ ++ +++ N R +
Sbjct: 248 SMLTVNPKKRITADQALKVPWIC---NRERVASAIHRQDTVDCLKKFNARRKLKGAILTT 304
Query: 465 CISEHEVDTAVGGIGHKIKNAVGKFLPSTKSNDESNTNSVNEFNDS 510
I+ + +G + N + PST ++ ++++ NDS
Sbjct: 305 MIATRN----LSNLGRNLLNKKEQGPPSTIKESSESSQTIDD-NDS 345
>CE28054 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 482
Score = 91.7 bits (226), Expect = 6e-18
Identities = 98/406 (24%), Positives = 162/406 (39%), Gaps = 72/406 (17%)
Query: 110 KVLNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGI 169
K + Y++ EELG G V+ T A KI+N K S
Sbjct: 7 KFSDNYDVKEELGKGAFSVVRRCVHKTTGLEFAAKIINTKKL---------------SAR 51
Query: 170 EDEKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKAR 229
+ +K++RE I +K H ++V+L + + + YLV + + GE+ D++ +
Sbjct: 52 DFQKLEREARICRKLQHPNIVRLHDSIQEESFH--YLVFDLVTGGELF---EDIVARE-- 104
Query: 230 GPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLL---SEDGIVKISDFGVXXX 286
S + +L + Y H GI+HRD+KP NLLL ++ VK++DFG+
Sbjct: 105 ---FYSEADASHCIQQILESIAYCHSNGIVHRDLKPENLLLASKAKGAAVKLADFGLAIE 161
Query: 287 XXXXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMG 346
AGTP + +PE+ +KK DP SK P DIWA G
Sbjct: 162 VNDSEAWHGF--------AGTPGYLSPEV------LKK---DPYSK------PVDIWACG 198
Query: 347 ITLHCLLFGMLPFISDYELELFDKIVNEPLVFEPYQKIEQCQVSQVECKEEYEEAQXXXX 406
+ L+ LL G PF + + L+ +I K E EA+
Sbjct: 199 VILYILLVGYPPFWDEDQHRLYAQI-----------KAGAYDYPSPEWDTVTPEAKSLID 247
Query: 407 XXXXXXXXXRMAIQDAKKHPWVCWDFNHNDYMS--DQEKSLKLIEQSNFHRSPSEQVEQI 464
R+ A K PW+C N S ++ ++ +++ N R +
Sbjct: 248 SMLTVNPKKRITADQALKVPWIC---NRERVASAIHRQDTVDCLKKFNARRKLKGAILTT 304
Query: 465 CISEHEVDTAVGGIGHKIKNAVGKFLPSTKSNDESNTNSVNEFNDS 510
I+ + +G + N + PST ++ ++++ NDS
Sbjct: 305 MIATRN----LSNLGRNLLNKKEQGPPSTIKESSESSQTIDD-NDS 345
>CE00847 [T] KOG0583 Serine/threonine protein kinase
Length = 622
Score = 91.7 bits (226), Expect = 6e-18
Identities = 72/260 (27%), Positives = 111/260 (42%), Gaps = 46/260 (17%)
Query: 112 LNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIED 171
+ + I E +G G G VK + T VAIKI+NR + +
Sbjct: 21 IGNFVIKETIGKGAFGAVKRGTHIQTGYDVAIKILNRGRMKGLGTV-------------- 66
Query: 172 EKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKARGP 231
K + EI ++K H H+ +L V+ I+LV+E S GE+ I K P
Sbjct: 67 NKTRNEIDNLQKLTHPHITRLFRVISTPSD--IFLVMELVSGGELF----SYITRKGALP 120
Query: 232 PLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXXXXXXXX 291
+ +R F+ ++ G+ Y H I+HRD+KP NLLL + +KI+DFG+
Sbjct: 121 ----IRESRRYFQQIISGVSYCHNHMIVHRDLKPENLLLDANKNIKIADFGL-------- 168
Query: 292 XXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGITLHC 351
+ G+P + APE+ S + + D+W+ G+ L+
Sbjct: 169 SNYMTDGDLLSTACGSPNYAAPELI--------------SNKLYVGPEVDLWSCGVILYA 214
Query: 352 LLFGMLPFISDYELELFDKI 371
+L G LPF LF KI
Sbjct: 215 MLCGTLPFDDQNVPTLFAKI 234
>Hs16950621 [Z] KOG0613 Projectin/twitchin and related proteins
Length = 992
Score = 91.3 bits (225), Expect = 7e-18
Identities = 79/329 (24%), Positives = 142/329 (43%), Gaps = 66/329 (20%)
Query: 107 SKRKVLNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQ 166
+++KV + Y+I E LG G+ G+V ++V + ++ + KF +
Sbjct: 534 TEQKVSDFYDIEERLGSGKFGQV-------------FRLVEKKTRKVWAGKFFKAY---- 576
Query: 167 SGIEDEKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIET 226
S E E I++EI+IM HH +V+ ++ ++ + I +VLE S GE+ E
Sbjct: 577 SAKEKENIRQEISIMNCLHHPKLVQCVDAFEEKAN--IVMVLEIVSGGEL-------FER 627
Query: 227 KARGPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLL-LSEDGI-VKISDFGVX 284
L+ + + R + G+EY+H QGI+H D+KP N++ +++ G +K+ DFG+
Sbjct: 628 IIDEDFELTERECIKYMRQISEGVEYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFGLA 687
Query: 285 XXXXXXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWA 344
GTP F APE+ E I + TD+W+
Sbjct: 688 RRLENAGSLKVLF--------GTPEFVAPEVINYEP---------------IGYATDMWS 724
Query: 345 MGITLHCLLFGMLPFISDYELELFDKIVNEPLVF--EPYQKIEQCQVSQVECKEEYEEAQ 402
+G+ + L+ G+ PF+ D + E + + F E + +I ++A+
Sbjct: 725 IGVICYILVSGLSPFMGDNDNETLANVTSATWDFDDEAFDEIS-------------DDAK 771
Query: 403 XXXXXXXXXXXXXRMAIQDAKKHPWVCWD 431
R+ +HPW+ D
Sbjct: 772 DFISNLLKKDMKNRLDCTQCLQHPWLMKD 800
>Hs16950613 [Z] KOG0613 Projectin/twitchin and related proteins
Length = 1845
Score = 91.3 bits (225), Expect = 7e-18
Identities = 79/329 (24%), Positives = 142/329 (43%), Gaps = 66/329 (20%)
Query: 107 SKRKVLNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQ 166
+++KV + Y+I E LG G+ G+V ++V + ++ + KF +
Sbjct: 1387 TEQKVSDFYDIEERLGSGKFGQV-------------FRLVEKKTRKVWAGKFFKAY---- 1429
Query: 167 SGIEDEKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIET 226
S E E I++EI+IM HH +V+ ++ ++ + I +VLE S GE+ E
Sbjct: 1430 SAKEKENIRQEISIMNCLHHPKLVQCVDAFEEKAN--IVMVLEIVSGGEL-------FER 1480
Query: 227 KARGPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLL-LSEDGI-VKISDFGVX 284
L+ + + R + G+EY+H QGI+H D+KP N++ +++ G +K+ DFG+
Sbjct: 1481 IIDEDFELTERECIKYMRQISEGVEYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFGLA 1540
Query: 285 XXXXXXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWA 344
GTP F APE+ E I + TD+W+
Sbjct: 1541 RRLENAGSLKVLF--------GTPEFVAPEVINYEP---------------IGYATDMWS 1577
Query: 345 MGITLHCLLFGMLPFISDYELELFDKIVNEPLVF--EPYQKIEQCQVSQVECKEEYEEAQ 402
+G+ + L+ G+ PF+ D + E + + F E + +I ++A+
Sbjct: 1578 IGVICYILVSGLSPFMGDNDNETLANVTSATWDFDDEAFDEIS-------------DDAK 1624
Query: 403 XXXXXXXXXXXXXRMAIQDAKKHPWVCWD 431
R+ +HPW+ D
Sbjct: 1625 DFISNLLKKDMKNRLDCTQCLQHPWLMKD 1653
>Hs16950611 [Z] KOG0613 Projectin/twitchin and related proteins
Length = 1914
Score = 91.3 bits (225), Expect = 7e-18
Identities = 79/329 (24%), Positives = 142/329 (43%), Gaps = 66/329 (20%)
Query: 107 SKRKVLNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQ 166
+++KV + Y+I E LG G+ G+V ++V + ++ + KF +
Sbjct: 1456 TEQKVSDFYDIEERLGSGKFGQV-------------FRLVEKKTRKVWAGKFFKAY---- 1498
Query: 167 SGIEDEKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIET 226
S E E I++EI+IM HH +V+ ++ ++ + I +VLE S GE+ E
Sbjct: 1499 SAKEKENIRQEISIMNCLHHPKLVQCVDAFEEKAN--IVMVLEIVSGGEL-------FER 1549
Query: 227 KARGPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLL-LSEDGI-VKISDFGVX 284
L+ + + R + G+EY+H QGI+H D+KP N++ +++ G +K+ DFG+
Sbjct: 1550 IIDEDFELTERECIKYMRQISEGVEYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFGLA 1609
Query: 285 XXXXXXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWA 344
GTP F APE+ E I + TD+W+
Sbjct: 1610 RRLENAGSLKVLF--------GTPEFVAPEVINYEP---------------IGYATDMWS 1646
Query: 345 MGITLHCLLFGMLPFISDYELELFDKIVNEPLVF--EPYQKIEQCQVSQVECKEEYEEAQ 402
+G+ + L+ G+ PF+ D + E + + F E + +I ++A+
Sbjct: 1647 IGVICYILVSGLSPFMGDNDNETLANVTSATWDFDDEAFDEIS-------------DDAK 1693
Query: 403 XXXXXXXXXXXXXRMAIQDAKKHPWVCWD 431
R+ +HPW+ D
Sbjct: 1694 DFISNLLKKDMKNRLDCTQCLQHPWLMKD 1722
>Hs16950601 [Z] KOG0613 Projectin/twitchin and related proteins
Length = 991
Score = 91.3 bits (225), Expect = 7e-18
Identities = 79/329 (24%), Positives = 142/329 (43%), Gaps = 66/329 (20%)
Query: 107 SKRKVLNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQ 166
+++KV + Y+I E LG G+ G+V ++V + ++ + KF +
Sbjct: 534 TEQKVSDFYDIEERLGSGKFGQV-------------FRLVEKKTRKVWAGKFFKAY---- 576
Query: 167 SGIEDEKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIET 226
S E E I++EI+IM HH +V+ ++ ++ + I +VLE S GE+ E
Sbjct: 577 SAKEKENIRQEISIMNCLHHPKLVQCVDAFEEKAN--IVMVLEIVSGGEL-------FER 627
Query: 227 KARGPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLL-LSEDGI-VKISDFGVX 284
L+ + + R + G+EY+H QGI+H D+KP N++ +++ G +K+ DFG+
Sbjct: 628 IIDEDFELTERECIKYMRQISEGVEYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFGLA 687
Query: 285 XXXXXXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWA 344
GTP F APE+ E I + TD+W+
Sbjct: 688 RRLENAGSLKVLF--------GTPEFVAPEVINYEP---------------IGYATDMWS 724
Query: 345 MGITLHCLLFGMLPFISDYELELFDKIVNEPLVF--EPYQKIEQCQVSQVECKEEYEEAQ 402
+G+ + L+ G+ PF+ D + E + + F E + +I ++A+
Sbjct: 725 IGVICYILVSGLSPFMGDNDNETLANVTSATWDFDDEAFDEIS-------------DDAK 771
Query: 403 XXXXXXXXXXXXXRMAIQDAKKHPWVCWD 431
R+ +HPW+ D
Sbjct: 772 DFISNLLKKDMKNRLDCTQCLQHPWLMKD 800
>CE27965 [T] KOG0574 STE20-like serine/threonine kinase MST
Length = 525
Score = 91.3 bits (225), Expect = 7e-18
Identities = 79/261 (30%), Positives = 117/261 (44%), Gaps = 50/261 (19%)
Query: 115 YEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIEDEKI 174
++I+ +LG G +G V A + ++AIK K P E I
Sbjct: 63 FDIVGKLGEGSYGSVHKAIHRESGHVLAIK------------------KVPVDTDLQEII 104
Query: 175 KREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKARGPPLL 234
K EI+IM++C ++VVK K +++V+EYC G I D++ +AR PL
Sbjct: 105 K-EISIMQQCKSKYVVKYYGSY--FKHSDLWIVMEYCGAGSIS----DIM--RARRKPL- 154
Query: 235 SFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXXXXXXXXXXX 294
S Q + R L GL+YLH IHRDIK N+LL+ DGI K++DFGV
Sbjct: 155 SEQEISAVLRDTLKGLQYLHDLKKIHRDIKAGNILLNTDGIAKLADFGVAGQLTDTMAKR 214
Query: 295 XXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGITLHCLLF 354
GTP + APE+ I++ D + DIW++GIT +
Sbjct: 215 NT-------VIGTPFWMAPEV------IEEIGYDTKA---------DIWSLGITAIEMAE 252
Query: 355 GMLPFISDYELELFDKIVNEP 375
G P+ + + I +P
Sbjct: 253 GRPPYSDIHPMRAIFMIPTKP 273
>CE27726 [T] KOG0574 STE20-like serine/threonine kinase MST
Length = 640
Score = 91.3 bits (225), Expect = 7e-18
Identities = 79/261 (30%), Positives = 117/261 (44%), Gaps = 50/261 (19%)
Query: 115 YEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIEDEKI 174
++I+ +LG G +G V A + ++AIK K P E I
Sbjct: 35 FDIVGKLGEGSYGSVHKAIHRESGHVLAIK------------------KVPVDTDLQEII 76
Query: 175 KREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKARGPPLL 234
K EI+IM++C ++VVK K +++V+EYC G I D++ +AR PL
Sbjct: 77 K-EISIMQQCKSKYVVKYYGSY--FKHSDLWIVMEYCGAGSIS----DIM--RARRKPL- 126
Query: 235 SFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXXXXXXXXXXX 294
S Q + R L GL+YLH IHRDIK N+LL+ DGI K++DFGV
Sbjct: 127 SEQEISAVLRDTLKGLQYLHDLKKIHRDIKAGNILLNTDGIAKLADFGVAGQLTDTMAKR 186
Query: 295 XXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGITLHCLLF 354
GTP + APE+ I++ D + DIW++GIT +
Sbjct: 187 NT-------VIGTPFWMAPEV------IEEIGYDTKA---------DIWSLGITAIEMAE 224
Query: 355 GMLPFISDYELELFDKIVNEP 375
G P+ + + I +P
Sbjct: 225 GRPPYSDIHPMRAIFMIPTKP 245
>CE27082 [T] KOG0574 STE20-like serine/threonine kinase MST
Length = 421
Score = 91.3 bits (225), Expect = 7e-18
Identities = 79/261 (30%), Positives = 117/261 (44%), Gaps = 50/261 (19%)
Query: 115 YEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIEDEKI 174
++I+ +LG G +G V A + ++AIK K P E I
Sbjct: 35 FDIVGKLGEGSYGSVHKAIHRESGHVLAIK------------------KVPVDTDLQEII 76
Query: 175 KREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKARGPPLL 234
K EI+IM++C ++VVK K +++V+EYC G I D++ +AR PL
Sbjct: 77 K-EISIMQQCKSKYVVKYYGSY--FKHSDLWIVMEYCGAGSIS----DIM--RARRKPL- 126
Query: 235 SFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXXXXXXXXXXX 294
S Q + R L GL+YLH IHRDIK N+LL+ DGI K++DFGV
Sbjct: 127 SEQEISAVLRDTLKGLQYLHDLKKIHRDIKAGNILLNTDGIAKLADFGVAGQLTDTMAKR 186
Query: 295 XXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGITLHCLLF 354
GTP + APE+ I++ D + DIW++GIT +
Sbjct: 187 NT-------VIGTPFWMAPEV------IEEIGYDTKA---------DIWSLGITAIEMAE 224
Query: 355 GMLPFISDYELELFDKIVNEP 375
G P+ + + I +P
Sbjct: 225 GRPPYSDIHPMRAIFMIPTKP 245
>CE07064 [T] KOG0574 STE20-like serine/threonine kinase MST
Length = 523
Score = 91.3 bits (225), Expect = 7e-18
Identities = 79/261 (30%), Positives = 117/261 (44%), Gaps = 50/261 (19%)
Query: 115 YEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIEDEKI 174
++I+ +LG G +G V A + ++AIK K P E I
Sbjct: 63 FDIVGKLGEGSYGSVHKAIHRESGHVLAIK------------------KVPVDTDLQEII 104
Query: 175 KREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKARGPPLL 234
K EI+IM++C ++VVK K +++V+EYC G I D++ +AR PL
Sbjct: 105 K-EISIMQQCKSKYVVKYYGSY--FKHSDLWIVMEYCGAGSIS----DIM--RARRKPL- 154
Query: 235 SFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXXXXXXXXXXX 294
S Q + R L GL+YLH IHRDIK N+LL+ DGI K++DFGV
Sbjct: 155 SEQEISAVLRDTLKGLQYLHDLKKIHRDIKAGNILLNTDGIAKLADFGVAGQLTDTMAKR 214
Query: 295 XXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGITLHCLLF 354
GTP + APE+ I++ D + DIW++GIT +
Sbjct: 215 NT-------VIGTPFWMAPEV------IEEIGYDTKA---------DIWSLGITAIEMAE 252
Query: 355 GMLPFISDYELELFDKIVNEP 375
G P+ + + I +P
Sbjct: 253 GRPPYSDIHPMRAIFMIPTKP 273
>7299536 [D] KOG0580 Serine/threonine protein kinase
Length = 411
Score = 91.3 bits (225), Expect = 7e-18
Identities = 77/282 (27%), Positives = 124/282 (43%), Gaps = 52/282 (18%)
Query: 95 ETNTVSLEYDPISKRKV--LNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKR 152
E E P +K LN ++I LG G+ G V LAR+ ++ +VA+K++ + +
Sbjct: 132 EKEKTKTETQPQKPKKTWELNNFDIGRLLGRGKFGNVYLAREKESQFVVALKVLFKRQ-- 189
Query: 153 TFNDKFSNRFKTPQSGIEDEKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCS 212
+S +E + ++REI I H H+++L D +IYL+LEY
Sbjct: 190 -----------IGESNVEHQ-VRREIEIQSHLRHPHILRLYAYFHD--DVRIYLILEYAP 235
Query: 213 KGEIKWCPGDVIETKARGPPLLSF--QRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLL 270
+G + + P+ F +++ + + L YLH + IIHRDIKP NLLL
Sbjct: 236 QG--------TLFNALQAQPMKRFDERQSATYIQALCSALLYLHERDIIHRDIKPENLLL 287
Query: 271 SEDGIVKISDFGVXXXXXXXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPN 330
G++KI+DFG GT + PE+ + P+
Sbjct: 288 GHKGVLKIADFG---------WSVHEPNSMRMTLCGTVDYLPPEMVQGK---------PH 329
Query: 331 SKEPIISFPTDIWAMGITLHCLLFGMLPFISDYELELFDKIV 372
+K D+W++G+ LL G PF S E + KI+
Sbjct: 330 TKN------VDLWSLGVLCFELLVGHAPFYSKNYDETYKKIL 365
>Hs5454094 [T] KOG0574 STE20-like serine/threonine kinase MST
Length = 491
Score = 90.9 bits (224), Expect = 9e-18
Identities = 77/284 (27%), Positives = 124/284 (43%), Gaps = 51/284 (17%)
Query: 92 PVKETNTVSLEYDPISKRKVLNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKK 151
P ++ L D ++K+ ++++E+LG G +G V A + Q+VAIK V
Sbjct: 5 PAPKSKLKKLSEDSLTKQPE-EVFDVLEKLGEGSYGSVFKAIHKESGQVVAIKQV----- 58
Query: 152 RTFNDKFSNRFKTPQSGIEDEKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYC 211
+S +++ I +EI+IM++C +VVK K+ +++V+EYC
Sbjct: 59 ------------PVESDLQE--IIKEISIMQQCDSPYVVKYYGSY--FKNTDLWIVMEYC 102
Query: 212 SKGEIKWCPGDVIETKARGPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLS 271
G + D+I + + L I + L GLEYLHF IHRDIK N+LL+
Sbjct: 103 GAGSVS----DIIRLRNK---TLIEDEIATILKSTLKGLEYLHFMRKIHRDIKAGNILLN 155
Query: 272 EDGIVKISDFGVXXXXXXXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNS 331
+G K++DFGV GTP + APE+
Sbjct: 156 TEGHAKLADFGVAGQLTDTMAKRNT-------VIGTPFWMAPEVI--------------- 193
Query: 332 KEPIISFPTDIWAMGITLHCLLFGMLPFISDYELELFDKIVNEP 375
+E + DIW++GIT + G P+ + + I P
Sbjct: 194 QEIGYNCVADIWSLGITSIEMAEGKPPYADIHPMRAIFMIPTNP 237
>Hs16178962 [T] KOG0574 STE20-like serine/threonine kinase MST
Length = 491
Score = 90.9 bits (224), Expect = 9e-18
Identities = 77/284 (27%), Positives = 124/284 (43%), Gaps = 51/284 (17%)
Query: 92 PVKETNTVSLEYDPISKRKVLNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKK 151
P ++ L D ++K+ ++++E+LG G +G V A + Q+VAIK V
Sbjct: 5 PAPKSKLKKLSEDSLTKQPE-EVFDVLEKLGEGSYGSVFKAIHKESGQVVAIKQV----- 58
Query: 152 RTFNDKFSNRFKTPQSGIEDEKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYC 211
+S +++ I +EI+IM++C +VVK K+ +++V+EYC
Sbjct: 59 ------------PVESDLQE--IIKEISIMQQCDSPYVVKYYGSY--FKNTDLWIVMEYC 102
Query: 212 SKGEIKWCPGDVIETKARGPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLS 271
G + D+I + + L I + L GLEYLHF IHRDIK N+LL+
Sbjct: 103 GAGSVS----DIIRLRNK---TLIEDEIATILKSTLKGLEYLHFMRKIHRDIKAGNILLN 155
Query: 272 EDGIVKISDFGVXXXXXXXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNS 331
+G K++DFGV GTP + APE+
Sbjct: 156 TEGHAKLADFGVAGQLTDTMAKRNT-------VIGTPFWMAPEVI--------------- 193
Query: 332 KEPIISFPTDIWAMGITLHCLLFGMLPFISDYELELFDKIVNEP 375
+E + DIW++GIT + G P+ + + I P
Sbjct: 194 QEIGYNCVADIWSLGITSIEMAEGKPPYADIHPMRAIFMIPTNP 237
>CE28061 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 302
Score = 90.9 bits (224), Expect = 9e-18
Identities = 85/323 (26%), Positives = 130/323 (39%), Gaps = 62/323 (19%)
Query: 110 KVLNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGI 169
K + Y++ EELG G V+ T A KI+N K S
Sbjct: 7 KFSDNYDVKEELGKGAFSVVRRCVHKTTGLEFAAKIINTKKL---------------SAR 51
Query: 170 EDEKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKAR 229
+ +K++RE I +K H ++V+L + + + YLV + + GE+ D++ +
Sbjct: 52 DFQKLEREARICRKLQHPNIVRLHDSIQEESFH--YLVFDLVTGGELF---EDIVARE-- 104
Query: 230 GPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLL---SEDGIVKISDFGVXXX 286
S + +L + Y H GI+HRD+KP NLLL ++ VK++DFG+
Sbjct: 105 ---FYSEADASHCIQQILESIAYCHSNGIVHRDLKPENLLLASKAKGAAVKLADFGLAIE 161
Query: 287 XXXXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMG 346
AGTP + +PE+ +KK DP SK P DIWA G
Sbjct: 162 VNDSEAWHGF--------AGTPGYLSPEV------LKK---DPYSK------PVDIWACG 198
Query: 347 ITLHCLLFGMLPFISDYELELFDKIVNEPLVFEPYQKIEQCQVSQVECKEEYEEAQXXXX 406
+ L+ LL G PF + + L+ +I K E EA+
Sbjct: 199 VILYILLVGYPPFWDEDQHRLYAQI-----------KAGAYDYPSPEWDTVTPEAKSLID 247
Query: 407 XXXXXXXXXRMAIQDAKKHPWVC 429
R+ A K PW+C
Sbjct: 248 SMLTVNPKKRITADQALKVPWIC 270
>CE28060 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 302
Score = 90.9 bits (224), Expect = 9e-18
Identities = 85/323 (26%), Positives = 130/323 (39%), Gaps = 62/323 (19%)
Query: 110 KVLNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGI 169
K + Y++ EELG G V+ T A KI+N K S
Sbjct: 7 KFSDNYDVKEELGKGAFSVVRRCVHKTTGLEFAAKIINTKKL---------------SAR 51
Query: 170 EDEKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKAR 229
+ +K++RE I +K H ++V+L + + + YLV + + GE+ D++ +
Sbjct: 52 DFQKLEREARICRKLQHPNIVRLHDSIQEESFH--YLVFDLVTGGELF---EDIVARE-- 104
Query: 230 GPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLL---SEDGIVKISDFGVXXX 286
S + +L + Y H GI+HRD+KP NLLL ++ VK++DFG+
Sbjct: 105 ---FYSEADASHCIQQILESIAYCHSNGIVHRDLKPENLLLASKAKGAAVKLADFGLAIE 161
Query: 287 XXXXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMG 346
AGTP + +PE+ +KK DP SK P DIWA G
Sbjct: 162 VNDSEAWHGF--------AGTPGYLSPEV------LKK---DPYSK------PVDIWACG 198
Query: 347 ITLHCLLFGMLPFISDYELELFDKIVNEPLVFEPYQKIEQCQVSQVECKEEYEEAQXXXX 406
+ L+ LL G PF + + L+ +I K E EA+
Sbjct: 199 VILYILLVGYPPFWDEDQHRLYAQI-----------KAGAYDYPSPEWDTVTPEAKSLID 247
Query: 407 XXXXXXXXXRMAIQDAKKHPWVC 429
R+ A K PW+C
Sbjct: 248 SMLTVNPKKRITADQALKVPWIC 270
>CE28058 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 571
Score = 90.9 bits (224), Expect = 9e-18
Identities = 85/323 (26%), Positives = 130/323 (39%), Gaps = 62/323 (19%)
Query: 110 KVLNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGI 169
K + Y++ EELG G V+ T A KI+N K S
Sbjct: 7 KFSDNYDVKEELGKGAFSVVRRCVHKTTGLEFAAKIINTKKL---------------SAR 51
Query: 170 EDEKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKAR 229
+ +K++RE I +K H ++V+L + + + YLV + + GE+ D++ +
Sbjct: 52 DFQKLEREARICRKLQHPNIVRLHDSIQEESFH--YLVFDLVTGGELF---EDIVARE-- 104
Query: 230 GPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLL---SEDGIVKISDFGVXXX 286
S + +L + Y H GI+HRD+KP NLLL ++ VK++DFG+
Sbjct: 105 ---FYSEADASHCIQQILESIAYCHSNGIVHRDLKPENLLLASKAKGAAVKLADFGLAIE 161
Query: 287 XXXXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMG 346
AGTP + +PE+ +KK DP SK P DIWA G
Sbjct: 162 VNDSEAWHGF--------AGTPGYLSPEV------LKK---DPYSK------PVDIWACG 198
Query: 347 ITLHCLLFGMLPFISDYELELFDKIVNEPLVFEPYQKIEQCQVSQVECKEEYEEAQXXXX 406
+ L+ LL G PF + + L+ +I K E EA+
Sbjct: 199 VILYILLVGYPPFWDEDQHRLYAQI-----------KAGAYDYPSPEWDTVTPEAKSLID 247
Query: 407 XXXXXXXXXRMAIQDAKKHPWVC 429
R+ A K PW+C
Sbjct: 248 SMLTVNPKKRITADQALKVPWIC 270
>CE28056 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 518
Score = 90.9 bits (224), Expect = 9e-18
Identities = 85/323 (26%), Positives = 130/323 (39%), Gaps = 62/323 (19%)
Query: 110 KVLNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGI 169
K + Y++ EELG G V+ T A KI+N K S
Sbjct: 7 KFSDNYDVKEELGKGAFSVVRRCVHKTTGLEFAAKIINTKKL---------------SAR 51
Query: 170 EDEKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKAR 229
+ +K++RE I +K H ++V+L + + + YLV + + GE+ D++ +
Sbjct: 52 DFQKLEREARICRKLQHPNIVRLHDSIQEESFH--YLVFDLVTGGELF---EDIVARE-- 104
Query: 230 GPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLL---SEDGIVKISDFGVXXX 286
S + +L + Y H GI+HRD+KP NLLL ++ VK++DFG+
Sbjct: 105 ---FYSEADASHCIQQILESIAYCHSNGIVHRDLKPENLLLASKAKGAAVKLADFGLAIE 161
Query: 287 XXXXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMG 346
AGTP + +PE+ +KK DP SK P DIWA G
Sbjct: 162 VNDSEAWHGF--------AGTPGYLSPEV------LKK---DPYSK------PVDIWACG 198
Query: 347 ITLHCLLFGMLPFISDYELELFDKIVNEPLVFEPYQKIEQCQVSQVECKEEYEEAQXXXX 406
+ L+ LL G PF + + L+ +I K E EA+
Sbjct: 199 VILYILLVGYPPFWDEDQHRLYAQI-----------KAGAYDYPSPEWDTVTPEAKSLID 247
Query: 407 XXXXXXXXXRMAIQDAKKHPWVC 429
R+ A K PW+C
Sbjct: 248 SMLTVNPKKRITADQALKVPWIC 270
>CE28055 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 533
Score = 90.9 bits (224), Expect = 9e-18
Identities = 85/323 (26%), Positives = 130/323 (39%), Gaps = 62/323 (19%)
Query: 110 KVLNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGI 169
K + Y++ EELG G V+ T A KI+N K S
Sbjct: 7 KFSDNYDVKEELGKGAFSVVRRCVHKTTGLEFAAKIINTKKL---------------SAR 51
Query: 170 EDEKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKAR 229
+ +K++RE I +K H ++V+L + + + YLV + + GE+ D++ +
Sbjct: 52 DFQKLEREARICRKLQHPNIVRLHDSIQEESFH--YLVFDLVTGGELF---EDIVARE-- 104
Query: 230 GPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLL---SEDGIVKISDFGVXXX 286
S + +L + Y H GI+HRD+KP NLLL ++ VK++DFG+
Sbjct: 105 ---FYSEADASHCIQQILESIAYCHSNGIVHRDLKPENLLLASKAKGAAVKLADFGLAIE 161
Query: 287 XXXXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMG 346
AGTP + +PE+ +KK DP SK P DIWA G
Sbjct: 162 VNDSEAWHGF--------AGTPGYLSPEV------LKK---DPYSK------PVDIWACG 198
Query: 347 ITLHCLLFGMLPFISDYELELFDKIVNEPLVFEPYQKIEQCQVSQVECKEEYEEAQXXXX 406
+ L+ LL G PF + + L+ +I K E EA+
Sbjct: 199 VILYILLVGYPPFWDEDQHRLYAQI-----------KAGAYDYPSPEWDTVTPEAKSLID 247
Query: 407 XXXXXXXXXRMAIQDAKKHPWVC 429
R+ A K PW+C
Sbjct: 248 SMLTVNPKKRITADQALKVPWIC 270
>CE28053 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 720
Score = 90.9 bits (224), Expect = 9e-18
Identities = 85/323 (26%), Positives = 130/323 (39%), Gaps = 62/323 (19%)
Query: 110 KVLNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGI 169
K + Y++ EELG G V+ T A KI+N K S
Sbjct: 7 KFSDNYDVKEELGKGAFSVVRRCVHKTTGLEFAAKIINTKKL---------------SAR 51
Query: 170 EDEKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKAR 229
+ +K++RE I +K H ++V+L + + + YLV + + GE+ D++ +
Sbjct: 52 DFQKLEREARICRKLQHPNIVRLHDSIQEESFH--YLVFDLVTGGELF---EDIVARE-- 104
Query: 230 GPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLL---SEDGIVKISDFGVXXX 286
S + +L + Y H GI+HRD+KP NLLL ++ VK++DFG+
Sbjct: 105 ---FYSEADASHCIQQILESIAYCHSNGIVHRDLKPENLLLASKAKGAAVKLADFGLAIE 161
Query: 287 XXXXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMG 346
AGTP + +PE+ +KK DP SK P DIWA G
Sbjct: 162 VNDSEAWHGF--------AGTPGYLSPEV------LKK---DPYSK------PVDIWACG 198
Query: 347 ITLHCLLFGMLPFISDYELELFDKIVNEPLVFEPYQKIEQCQVSQVECKEEYEEAQXXXX 406
+ L+ LL G PF + + L+ +I K E EA+
Sbjct: 199 VILYILLVGYPPFWDEDQHRLYAQI-----------KAGAYDYPSPEWDTVTPEAKSLID 247
Query: 407 XXXXXXXXXRMAIQDAKKHPWVC 429
R+ A K PW+C
Sbjct: 248 SMLTVNPKKRITADQALKVPWIC 270
>CE28051 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 559
Score = 90.9 bits (224), Expect = 9e-18
Identities = 85/323 (26%), Positives = 130/323 (39%), Gaps = 62/323 (19%)
Query: 110 KVLNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGI 169
K + Y++ EELG G V+ T A KI+N K S
Sbjct: 7 KFSDNYDVKEELGKGAFSVVRRCVHKTTGLEFAAKIINTKKL---------------SAR 51
Query: 170 EDEKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKAR 229
+ +K++RE I +K H ++V+L + + + YLV + + GE+ D++ +
Sbjct: 52 DFQKLEREARICRKLQHPNIVRLHDSIQEESFH--YLVFDLVTGGELF---EDIVARE-- 104
Query: 230 GPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLL---SEDGIVKISDFGVXXX 286
S + +L + Y H GI+HRD+KP NLLL ++ VK++DFG+
Sbjct: 105 ---FYSEADASHCIQQILESIAYCHSNGIVHRDLKPENLLLASKAKGAAVKLADFGLAIE 161
Query: 287 XXXXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMG 346
AGTP + +PE+ +KK DP SK P DIWA G
Sbjct: 162 VNDSEAWHGF--------AGTPGYLSPEV------LKK---DPYSK------PVDIWACG 198
Query: 347 ITLHCLLFGMLPFISDYELELFDKIVNEPLVFEPYQKIEQCQVSQVECKEEYEEAQXXXX 406
+ L+ LL G PF + + L+ +I K E EA+
Sbjct: 199 VILYILLVGYPPFWDEDQHRLYAQI-----------KAGAYDYPSPEWDTVTPEAKSLID 247
Query: 407 XXXXXXXXXRMAIQDAKKHPWVC 429
R+ A K PW+C
Sbjct: 248 SMLTVNPKKRITADQALKVPWIC 270
>At3g50500 [T] KOG0583 Serine/threonine protein kinase
Length = 362
Score = 90.9 bits (224), Expect = 9e-18
Identities = 72/264 (27%), Positives = 111/264 (41%), Gaps = 52/264 (19%)
Query: 115 YEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIEDEKI 174
Y+ ++++G G G +L D VTK+LVA+K + R +K DE +
Sbjct: 23 YDFVKDIGSGNFGVARLMTDRVTKELVAVKYIERGEK------------------IDENV 64
Query: 175 KREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKARGPPLL 234
+REI + H ++V+ EV+ + +V+EY + GE + +
Sbjct: 65 QREIINHRSLRHPNIVRFKEVI--LTPSHLAIVMEYAAGGE--------LYERICNAGRF 114
Query: 235 SFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLL--SEDGIVKISDFGVXXXXXXXXX 292
S R F+ ++ G+ Y H I HRD+K N LL S +KI DFG
Sbjct: 115 SEDEARFFFQQLISGVSYCHAMQICHRDLKLENTLLDGSPAPRLKICDFG--------YS 166
Query: 293 XXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGITLHCL 352
T GTPA+ APEI L ++ K D+W+ G+TL+ +
Sbjct: 167 KSSVLHSQPKSTVGTPAYIAPEILLRQEYDGKL--------------ADVWSCGVTLYVM 212
Query: 353 LFGMLPFISDYELELFDKIVNEPL 376
L G PF E + K + L
Sbjct: 213 LVGAYPFEDPQEPRDYRKTIQRIL 236
>At3g07980 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 1367
Score = 90.9 bits (224), Expect = 9e-18
Identities = 77/269 (28%), Positives = 121/269 (44%), Gaps = 48/269 (17%)
Query: 108 KRKVL-NTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQ 166
K K L N Y + +E+G G +G+V + DL VAIK V+
Sbjct: 12 KSKTLDNKYMLGDEIGKGAYGRVYIGLDLENGDFVAIKQVSLEN---------------- 55
Query: 167 SGIED-EKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIE 225
G ED I +EI ++K +H+++VK + L ++++LEY G + ++I+
Sbjct: 56 IGQEDLNTIMQEIDLLKNLNHKNIVKYLGSLKT--KTHLHIILEYVENGSL----ANIIK 109
Query: 226 TKARGPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXX 285
GP S VL GL YLH QG+IHRDIK AN+L +++G+VK++DFGV
Sbjct: 110 PNKFGPFPESLVTV--YIAQVLEGLVYLHEQGVIHRDIKGANILTTKEGLVKLADFGVAT 167
Query: 286 XXXXXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAM 345
GTP + APE+ + + +DIW++
Sbjct: 168 KLNEADFNTH-------SVVGTPYWMAPEVIELSG---------------VCAASDIWSV 205
Query: 346 GITLHCLLFGMLPFISDYELELFDKIVNE 374
G T+ LL + P+ + +IV +
Sbjct: 206 GCTIIELLTCVPPYYDLQPMPALYRIVQD 234
>YPL150w [T] KOG0583 Serine/threonine protein kinase
Length = 901
Score = 90.5 bits (223), Expect = 1e-17
Identities = 78/307 (25%), Positives = 127/307 (40%), Gaps = 70/307 (22%)
Query: 69 LHQNHIRTVLGSHLNS-GQRITYGPVKETNTVSLEYDPISKRKVLNTYEIIEELGHGQHG 127
L QN+I++++GS N + T + E + Y+I++++G G G
Sbjct: 10 LEQNNIKSIIGSSYNRLYSQFTSDELTE----------------VGNYKILKQIGEGSFG 53
Query: 128 KVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIEDEKIKREIAIMKKCHHE 187
KV LA T + V +K +++ D I RE+ ++
Sbjct: 54 KVYLALHRPTHRKVCLKTSDKN---------------------DPNIVREVFYHRQFDFP 92
Query: 188 HVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKARGPPLLSFQRTREIFRGVL 247
++ KL EV+ K+++ LEYC PG + +S E+F +
Sbjct: 93 YITKLYEVI--VTESKVWMALEYC--------PGKELYDHLLSLRRISLLECGELFAQIS 142
Query: 248 LGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXXXXXXXXXXXXXXXXXXAKTAGT 307
+ Y H +HRD+K N+LL ++G K++DFG GT
Sbjct: 143 GAVYYAHSMHCVHRDLKLENILLDKNGNAKLTDFGFTRECMTKTTLET--------VCGT 194
Query: 308 PAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGITLHCLLFGMLPFISDYELEL 367
+ APE+ I++ D F DIW++G+ L+ L+ G LPF D E +
Sbjct: 195 TVYMAPEL------IERRTYD--------GFKIDIWSLGVILYTLITGYLPFDDDDEAKT 240
Query: 368 FDKIVNE 374
KIVNE
Sbjct: 241 KWKIVNE 247
>CE14798 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 422
Score = 90.5 bits (223), Expect = 1e-17
Identities = 72/269 (26%), Positives = 119/269 (43%), Gaps = 45/269 (16%)
Query: 108 KRKVLNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQS 167
K N ++ + +G G G+V R TK++ A+KI+++ R N+
Sbjct: 87 KTATANDFDYLTTIGKGSFGRVYQVRHKETKKIYAMKILSKEHIRKKNE----------- 135
Query: 168 GIEDEKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETK 227
++ +R + I H +V L + + K+Y VL++ + GE+ +
Sbjct: 136 -VKHVMAERNVLI-NNFKHPFLVSLHFSFQNKE--KLYFVLDHLNGGELF--------SH 183
Query: 228 ARGPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXXXX 287
+ S R+R + L YLH + II+RD+KP NLLL + G + ++DFG+
Sbjct: 184 LQREKHFSESRSRFYAAEIACALGYLHEKNIIYRDLKPENLLLDDKGYLVLTDFGLCKED 243
Query: 288 XXXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGI 347
GTP + APEI L K+P D W +G
Sbjct: 244 MQGSKTTSTF-------CGTPEYLAPEIIL--------------KKP-YDKTVDWWCLGS 281
Query: 348 TLHCLLFGMLPFISDYELELFDKIVNEPL 376
L+ ++FG+ PF S E++DKI+N+PL
Sbjct: 282 VLYEMIFGLPPFYSKDHNEMYDKIINQPL 310
>7304358 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 493
Score = 90.5 bits (223), Expect = 1e-17
Identities = 86/328 (26%), Positives = 134/328 (40%), Gaps = 61/328 (18%)
Query: 105 PISKRKVLNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKT 164
P + + + Y+I EELG G VK T A KI+N KK T D
Sbjct: 4 PAACTRFSDNYDIKEELGKGAFSIVKRCVQKSTGFEFAAKIINT-KKLTARDF------- 55
Query: 165 PQSGIEDEKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVI 224
+K++RE I +K HH ++V+L + + + YLV + + GE+ D++
Sbjct: 56 -------QKLEREARICRKLHHPNIVRLHDSIQEENYH--YLVFDLVTGGELF---EDIV 103
Query: 225 ETKARGPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLL---SEDGIVKISDF 281
+ S + +L + + H G++HRD+KP NLLL ++ VK++DF
Sbjct: 104 ARE-----FYSEADASHCIQQILESVNHCHQNGVVHRDLKPENLLLASKAKGAAVKLADF 158
Query: 282 GVXXXXXXXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTD 341
G+ AGTP + +PE+ +KK +P K D
Sbjct: 159 GLAIEVQGDHQAWFGF-------AGTPGYLSPEV------LKK---EPYGKS------VD 196
Query: 342 IWAMGITLHCLLFGMLPFISDYELELFDKIVNEPLVFEPYQKIEQCQVSQVECKEEYEEA 401
IWA G+ L+ LL G PF + + L+ +I K E EA
Sbjct: 197 IWACGVILYILLVGYPPFWDEDQHRLYSQI-----------KAGAYDYPSPEWDTVTPEA 245
Query: 402 QXXXXXXXXXXXXXRMAIQDAKKHPWVC 429
+ R+ +A KHPW+C
Sbjct: 246 KNLINQMLTVNPNKRITAAEALKHPWIC 273
>7298323 [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 514
Score = 90.1 bits (222), Expect = 2e-17
Identities = 97/400 (24%), Positives = 163/400 (40%), Gaps = 69/400 (17%)
Query: 105 PISKRKVLNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKT 164
P + R+ + + + + LG G +G+VKL + T + VA+K+V+ K
Sbjct: 12 PAATREFVEGWTLAQTLGEGAYGEVKLLINRQTGEAVAMKMVDLKKH------------- 58
Query: 165 PQSGIEDEKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVI 224
P + +++E+ I K +H+++ Y+ LEY + GE+ G+
Sbjct: 59 PDAA---NSVRKEVCIQKMLQDKHILRFFGKRSQGSVE--YIFLEYAAGGELFDRIGEEP 113
Query: 225 ETKARGPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVX 284
+ G P QR F +L GL YLH +GI HRD+KP NLLL E VKISDFG+
Sbjct: 114 DV---GMPQHEAQR---YFTQLLSGLNYLHQRGIAHRDLKPENLLLDEHDNVKISDFGMA 167
Query: 285 XXXXXXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWA 344
K GT + APE+ ++ + P D+W+
Sbjct: 168 TMFRCKGKERLLD-----KRCGTLPYVAPEVL---------------QKAYHAQPADLWS 207
Query: 345 MGITLHCLLFGMLPF--ISDYELELFDKIVNEPLVFE-PYQKIEQCQVSQVECKEEYEEA 401
G+ L +L G LP+ S E + N+ + P+ K++ +S +
Sbjct: 208 CGVILVTMLAGELPWDQPSTNCTEFTNWRDNDHWQLQTPWSKLDTLAISLLR-------- 259
Query: 402 QXXXXXXXXXXXXXRMAIQDAKKHPWVCWDFNHNDYMSDQEKSLKLIEQSNFHRSPSEQV 461
R+ ++ H W F N+ D S +E SP +
Sbjct: 260 -----KLLATSPGTRLTLEKTLDHKWCNMQFADNERSYDLVDSAAALEIC----SPKAKR 310
Query: 462 EQICISEHEVDTAVGGIGHKI-KNAVGKFLPSTKSNDESN 500
+++ S H G+ I +N + +P+ +S+D+ N
Sbjct: 311 QRLQSSAH----LSNGLDDSISRNYCSQPMPTMRSDDDFN 346
>Hs7657335 [T] KOG0587 Traf2- and Nck-interacting kinase and related germinal
center kinase (GCK) family protein kinases
Length = 1295
Score = 89.7 bits (221), Expect = 2e-17
Identities = 74/280 (26%), Positives = 125/280 (44%), Gaps = 48/280 (17%)
Query: 102 EYDPISKRKVLNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNR 161
+ D + R +E++E +G+G +G+V R + T QL AIK+++ +
Sbjct: 12 DIDLSALRDPAGIFELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTED---------- 61
Query: 162 FKTPQSGIEDEKIKREIAIMKK-CHHEHVVK----LIEVLDDAKSRKIYLVLEYCSKGEI 216
E+E+IK+EI ++KK HH ++ I+ +++LV+E+C G +
Sbjct: 62 --------EEEEIKQEINMLKKYSHHRNIATYYGAFIKKSPPGNDDQLWLVMEFCGAGSV 113
Query: 217 KWCPGDVIE-TKARGPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGI 275
D+++ TK L I R +L GL +LH +IHRDIK N+LL+E+
Sbjct: 114 T----DLVKNTKGNA---LKEDCIAYICREILRGLAHLHAHKVIHRDIKGQNVLLTENAE 166
Query: 276 VKISDFGVXXXXXXXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPI 335
VK+ DFGV GTP + APE+ ++ + +
Sbjct: 167 VKLVDFGVSAQLDRTVGRRNTF-------IGTPYWMAPEVIACDE----------NPDAT 209
Query: 336 ISFPTDIWAMGITLHCLLFGMLPFISDYELELFDKIVNEP 375
+ +DIW++GIT + G P + + I P
Sbjct: 210 YDYRSDIWSLGITAIEMAEGAPPLCDMHPMRALFLIPRNP 249
>7296128 [T] KOG0583 Serine/threonine protein kinase
Length = 550
Score = 89.7 bits (221), Expect = 2e-17
Identities = 65/251 (25%), Positives = 115/251 (44%), Gaps = 47/251 (18%)
Query: 112 LNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIED 171
+ Y ++G G KVKLA +T+ VAIK+V+ + +G++
Sbjct: 41 IGLYRFCGDIGRGNFSKVKLAVHQLTRDKVAIKVVDLDR----------------AGLDA 84
Query: 172 EKIKR---EIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKA 228
+ ++ EIA ++ HH ++++L EV++ ++YLV E+ GE+
Sbjct: 85 KALRMLSSEIATLECVHHPNILRLFEVVETLG--RVYLVTEWIRGGEL-------YNHIT 135
Query: 229 RGPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXXXXX 288
+G PL + + +LL ++++H G +HRDIK N+LL + +K++DFG
Sbjct: 136 QGGPLREIHAA-PLLKQLLLAVKHMHSLGYVHRDIKAENVLLLSEDRLKLADFGFSTQLI 194
Query: 289 XXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGIT 348
G+P + APE+ S + I P D+WA+GI
Sbjct: 195 NGTGANQKLDTF----CGSPPYAAPELF--------------SDDHYIGAPVDVWALGIL 236
Query: 349 LHCLLFGMLPF 359
L+ ++ G +PF
Sbjct: 237 LYFMVVGNMPF 247
>SPAC17G8.14c [T] KOG0694 Serine/threonine protein kinase
Length = 896
Score = 89.4 bits (220), Expect = 3e-17
Identities = 77/270 (28%), Positives = 119/270 (43%), Gaps = 44/270 (16%)
Query: 109 RKVLNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSG 168
R L+ + + LG G GKV LA V K+ AIK++ K+ ++ KT
Sbjct: 566 RVTLDDFTFLAVLGKGNFGKVMLAEYKVNKKFYAIKVLK--KEAILKNEELESLKT---- 619
Query: 169 IEDEKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKA 228
EK E+A +K H ++ L S ++Y V+EY G++ ++ +
Sbjct: 620 ---EKHVFEVANKEK--HPFLLNLFASFQT--STRVYFVMEYILGGDL------MVHIQR 666
Query: 229 RGPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXXXXX 288
+ S +R R V L L+Y H GI +RD+K N+LL DG ++I+D+G+
Sbjct: 667 QQ---FSVKRARFYGAEVCLALKYFHENGIAYRDLKLDNILLCPDGHIRIADYGLCKENM 723
Query: 289 XXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGIT 348
GTP F APEI L E S D WA G+
Sbjct: 724 LLGNTTSTF-------CGTPEFMAPEILL---------------EQQYSKDVDWWAFGVL 761
Query: 349 LHCLLFGMLPFISDYELELFDKIVNEPLVF 378
++ +L G PF + E E+FD I+++ +F
Sbjct: 762 MYQMLLGQSPFKGEDEEEIFDAILSDEPLF 791
>Hs4507273 [D] KOG0580 Serine/threonine protein kinase
Length = 275
Score = 89.4 bits (220), Expect = 3e-17
Identities = 78/271 (28%), Positives = 120/271 (43%), Gaps = 48/271 (17%)
Query: 108 KRKVLNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQS 167
+R ++ +EI LG G+ G V LAR + +VA+K++ F ++ + +
Sbjct: 2 RRLTVDDFEIGRPLGKGKFGNVYLARLKESHFIVALKVL-----------FKSQIE--KE 48
Query: 168 GIEDEKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETK 227
G+E + ++REI I H ++++L DA R++YL+LEY +GE+ +
Sbjct: 49 GLEHQ-LRREIEIQAHLQHPNILRLYNYFHDA--RRVYLILEYAPRGELY--------KE 97
Query: 228 ARGPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXXXX 287
+ L QRT I V L Y H + +IHRDIKP NLLL G VKI+DFG
Sbjct: 98 LQKSEKLDEQRTATIIEEVADALTYCHDKKVIHRDIKPENLLLGFRGEVKIADFG----- 152
Query: 288 XXXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGI 347
GT + PE+ +K DL W +G+
Sbjct: 153 ----WSVHTPLPERKTMCGTLDYLPPEMIEGRTYDEKVDL---------------WCIGV 193
Query: 348 TLHCLLFGMLPFISDYELELFDKIVNEPLVF 378
+ LL G PF S E + +I+ + F
Sbjct: 194 LCYELLVGYPPFESASHSETYRRILKVDVRF 224
>CE12518 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 391
Score = 89.4 bits (220), Expect = 3e-17
Identities = 69/269 (25%), Positives = 117/269 (42%), Gaps = 56/269 (20%)
Query: 115 YEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIEDEKI 174
YE++ +G G +V + VT++ A+K+VN + +
Sbjct: 71 YEVLAVVGKGSFSQVLRVQHRVTRKYFAVKVVNG---------------------DCGAV 109
Query: 175 KREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKARGPPLL 234
E+ I+ + H V++L EV S K+++V++ S GE+ D + K R
Sbjct: 110 NNELNILSRLSHPFVIRLEEVFKS--SSKLFIVMQMASGGEMY----DRVVAKGR----Y 159
Query: 235 SFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSE---DGIVKISDFGVXXXXXXXX 291
S + R + +L GL YLH + HRD+KP NLL ++ + + I+DFG+
Sbjct: 160 SEEEARNALKMLLTGLTYLHSIRVTHRDLKPENLLYADSRPEARLLITDFGL-------A 212
Query: 292 XXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGITLHC 351
+T GTP + APE+ L +K D+WA+G+ +
Sbjct: 213 YQATKPNETMTETCGTPEYIAPELLLRVPYTQK---------------VDMWAVGVIAYI 257
Query: 352 LLFGMLPFISDYELELFDKIVNEPLVFEP 380
L+ G++PF D L+ I+ V+ P
Sbjct: 258 LMSGIMPFDDDCRSRLYTHIITANYVYYP 286
>YJL164c [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 397
Score = 89.0 bits (219), Expect = 4e-17
Identities = 78/327 (23%), Positives = 135/327 (40%), Gaps = 68/327 (20%)
Query: 111 VLNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIE 170
V ++I+ LG G G+V L R + A+K++ + + R K +
Sbjct: 83 VYKNFQILRTLGTGSFGRVHLIRSRHNGRYYAMKVLKK--------EIVVRLKQVEH-TN 133
Query: 171 DEKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKARG 230
DE++ I H ++++ DA+ +I+++++Y GE+ ++ R
Sbjct: 134 DERLMLSIVT-----HPFIIRMWGTFQDAQ--QIFMIMDYIEGGELF----SLLRKSQRF 182
Query: 231 P-PLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXXXXXX 289
P P+ F V L LEYLH + II+RD+KP N+LL ++G +KI+DFG
Sbjct: 183 PNPVAKFYAAE-----VCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFAKYVPD 237
Query: 290 XXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGITL 349
GTP + APE+ + K D W+ GI +
Sbjct: 238 VTYT----------LCGTPDYIAPEVVSTKPYNKSIDW---------------WSFGILI 272
Query: 350 HCLLFGMLPFISDYELELFDKIVNEPLVFEPYQKIEQCQVSQVECKEEYEE--AQXXXXX 407
+ +L G PF ++ ++KI+N L F P+ E+ ++ ++
Sbjct: 273 YEMLAGYTPFYDSNTMKTYEKILNAELRFPPF------------FNEDVKDLLSRLITRD 320
Query: 408 XXXXXXXXRMAIQDAKKHPW---VCWD 431
+ +D K HPW V W+
Sbjct: 321 LSQRLGNLQNGTEDVKNHPWFKEVVWE 347
>YBL105c [T] KOG0694 Serine/threonine protein kinase
Length = 1151
Score = 89.0 bits (219), Expect = 4e-17
Identities = 76/271 (28%), Positives = 120/271 (44%), Gaps = 46/271 (16%)
Query: 108 KRKV-LNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQ 166
+RKV L+ + +++ LG G GKV L++ T +L AIK++ + +D S R +
Sbjct: 816 RRKVSLDNFVLLKVLGKGNFGKVILSKSKNTDRLCAIKVLKKDNIIQNHDIESARAE--- 872
Query: 167 SGIEDEKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIET 226
K+ + K H + L +IY +E+ G++ W +
Sbjct: 873 --------KKVFLLATKTKHPFLTNLY--CSFQTENRIYFAMEFIGGGDLMWHVQN---- 918
Query: 227 KARGPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXXX 286
LS +R + VLL L+Y H G+I+RD+K N+LL+ +G +KI+D+G+
Sbjct: 919 -----QRLSVRRAKFYAAEVLLALKYFHDNGVIYRDLKLENILLTPEGHIKIADYGLCKD 973
Query: 287 XXXXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMG 346
GTP F APEI KE + D WA G
Sbjct: 974 EMWYGNRTSTF-------CGTPEFMAPEIL---------------KEQEYTKAVDWWAFG 1011
Query: 347 ITLHCLLFGMLPFISDYELELFDKIV-NEPL 376
+ L+ +L PF D E E+F+ I+ +EPL
Sbjct: 1012 VLLYQMLLCQSPFSGDDEDEVFNAILTDEPL 1042
>SPBC4F6.06 [T] KOG0583 Serine/threonine protein kinase
Length = 891
Score = 89.0 bits (219), Expect = 4e-17
Identities = 77/289 (26%), Positives = 125/289 (42%), Gaps = 36/289 (12%)
Query: 97 NTVSLEYDPISKRKVLNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNR-HKKRTFN 155
++ S + P +RKV+ Y + + +G G GKVK+A L T + AIKIV R H T
Sbjct: 107 HSYSADEKPRERRKVIGNYVLGKTIGAGSMGKVKVAHHLKTGEQFAIKIVTRLHPDITKA 166
Query: 156 DKFSNRFKTPQSGIEDEK---IKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCS 212
++ T + E K RE A+ H ++ + +V + Y+V E+
Sbjct: 167 KAAASAEATKAAQSEKNKEIRTVREAALSTLLRHPYICEARDVY--ITNSHYYMVFEFVD 224
Query: 213 KGEIKWCPGDVIETKARGPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSE 272
G++ D I + + L ++ R+ R + L YLH ++HRD+K N+L+S+
Sbjct: 225 GGQML----DYIISHGK----LKEKQARKFVRQIGSALSYLHQNSVVHRDLKIENILISK 276
Query: 273 DGIVKISDFGVXXXXXXXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSK 332
G +KI DFG+ G+ F APE+ +
Sbjct: 277 TGDIKIIDFGLSNLYRRQSRLRTF--------CGSLYFAAPELL--------------NA 314
Query: 333 EPIISFPTDIWAMGITLHCLLFGMLPFISDYELELFDKIVNEPLVFEPY 381
+P I D+W+ GI L+ L+ G +PF L KI + + Y
Sbjct: 315 QPYIGPEVDVWSFGIVLYVLVCGKVPFDDQNMSALHAKIKKGTVEYPSY 363
>Hs4505695 [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 556
Score = 89.0 bits (219), Expect = 4e-17
Identities = 77/271 (28%), Positives = 115/271 (42%), Gaps = 50/271 (18%)
Query: 105 PISKRKVLNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKT 164
P ++K ++ + LG G V LAR+L T + AIKI+ + N K
Sbjct: 72 PQPRKKRPEDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKEN-------KV 124
Query: 165 PQSGIEDEKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEI-KWCP--G 221
P + RE +M + H VKL D K+Y L Y GE+ K+ G
Sbjct: 125 PY-------VTRERDVMSRLDHPFFVKLYFTFQD--DEKLYFGLSYAKNGELLKYIRKIG 175
Query: 222 DVIETKARGPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDF 281
ET TR ++ LEYLH +GIIHRD+KP N+LL+ED ++I+DF
Sbjct: 176 SFDETC-----------TRFYTAEIVSALEYLHGKGIIHRDLKPENILLNEDMHIQITDF 224
Query: 282 GVXXXXXXXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTD 341
G GT + +PE+ + K +D
Sbjct: 225 GTAKVLSPESKQARANSF-----VGTAQYVSPELLTEKSACKS---------------SD 264
Query: 342 IWAMGITLHCLLFGMLPFISDYELELFDKIV 372
+WA+G ++ L+ G+ PF + E +F KI+
Sbjct: 265 LWALGCIIYQLVAGLPPFRAGNEYLIFQKII 295
>CE21025 [D] KOG0580 Serine/threonine protein kinase
Length = 326
Score = 89.0 bits (219), Expect = 4e-17
Identities = 82/323 (25%), Positives = 136/323 (41%), Gaps = 73/323 (22%)
Query: 112 LNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTP--QSGI 169
L+ +++ LG G+ G V ++R+ TK+++A+K++ FKT Q G+
Sbjct: 41 LDDFDVGRPLGKGKFGNVFISREKKTKRIIALKVL---------------FKTQLLQLGV 85
Query: 170 EDEKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEI----KWCPGDVIE 225
+ +KREI I H +++ L D K +++++L+Y S+GE+ + PG +
Sbjct: 86 SHQ-LKREIEIQYHLRHPNILTLYGYFHDDK--RVFVILDYASRGELFNVLQSQPGHKVN 142
Query: 226 TKARGPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXX 285
G R + L Y H +G+IHRDIKP NLLL +K++DFG
Sbjct: 143 EVIAG----------RFVRQLANALHYCHSKGVIHRDIKPENLLLDSKLNLKLADFGWSV 192
Query: 286 XXXXXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAM 345
GT + APE+ S +P F DIWA+
Sbjct: 193 VADHSKRHT---------LCGTMDYLAPEMV--------------SNQP-HDFNVDIWAI 228
Query: 346 GITLHCLLFGMLPFISDYELELFDKIVNEPLVFEPYQKIEQCQVSQVECKEEYEEAQXXX 405
GI L +L G PF + + DK++ +I++C++ + A
Sbjct: 229 GILLFEMLVGYAPFAN----QTGDKLI---------ARIKECKIYIPSVVT--DGAASLI 273
Query: 406 XXXXXXXXXXRMAIQDAKKHPWV 428
R+ + D HPW+
Sbjct: 274 NAIIKKEPQERLPLVDIMAHPWI 296
>CE18454 [T] KOG4717 Serine/threonine protein kinase
Length = 1016
Score = 89.0 bits (219), Expect = 4e-17
Identities = 70/269 (26%), Positives = 122/269 (45%), Gaps = 48/269 (17%)
Query: 106 ISKRKVLNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTP 165
I ++ Y++ + +G G VKLA+ + T ++VA+KI++ KT
Sbjct: 18 IRDTRIAGLYDLEKTIGQGHFAVVKLAKHVFTGEMVAVKIID---------------KTK 62
Query: 166 QSGIEDEKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIE 225
+I +E+ MK H ++V+L EVLD KI+L+LE + D I
Sbjct: 63 MDEASTSQIMKEVRCMKLVQHANIVRLYEVLD--TQTKIFLILELGD-----YDLHDFII 115
Query: 226 TKARGPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSED-GIVKISDFGVX 284
+G + ++ F ++ ++Y H ++HRD+KP N++ E G+VK++DFG
Sbjct: 116 KHEKG---VCESLAQQYFCQIMTAIDYCHQLHVVHRDLKPENVVFFEKLGMVKLTDFGFS 172
Query: 285 XXXXXXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWA 344
+ G+ A+ APEI L + +D D+W+
Sbjct: 173 NSYEPGEQLNT--------SCGSLAYSAPEILLGD----SYDAP----------AVDVWS 210
Query: 345 MGITLHCLLFGMLPFISDYELELFDKIVN 373
+G+ L+ L+ G LPF + E KI++
Sbjct: 211 LGVILYMLVCGRLPFQEANDSETLTKILD 239
>7300106 [T] KOG0690 Serine/threonine protein kinase
Length = 530
Score = 89.0 bits (219), Expect = 4e-17
Identities = 75/271 (27%), Positives = 116/271 (42%), Gaps = 46/271 (16%)
Query: 108 KRKVLNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQS 167
K+ L +E ++ LG G GKV L R+ T +L AIKI+ KK K
Sbjct: 178 KKVTLENFEFLKVLGKGTFGKVILCREKATAKLYAIKIL---KKEVIIQKD--------- 225
Query: 168 GIEDEKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETK 227
E E ++K +H ++ L + ++ V++Y + GE+ W
Sbjct: 226 --EVAHTLTESRVLKSTNHPFLISLKYSFQT--NDRLCFVMQYVNGGELFW--------H 273
Query: 228 ARGPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXXXX 287
+ + RTR ++ L YLH QGII+RD+K NLLL +DG +K++DFG+
Sbjct: 274 LSHERIFTEDRTRFYGAEIISALGYLHSQGIIYRDLKLENLLLDKDGHIKVADFGLCKED 333
Query: 288 XXXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGI 347
GTP + APE+ LD N + D W G+
Sbjct: 334 ITYGRTTKTF-------CGTPEYLAPEV-----------LDDNDYGQAV----DWWGTGV 371
Query: 348 TLHCLLFGMLPFISDYELELFDKIVNEPLVF 378
++ ++ G LPF + LF I+ E + F
Sbjct: 372 VMYEMICGRLPFYNRDHDVLFTLILVEEVKF 402
>7293601 [T] KOG0577 Serine/threonine protein kinase
Length = 1039
Score = 89.0 bits (219), Expect = 4e-17
Identities = 73/245 (29%), Positives = 107/245 (42%), Gaps = 47/245 (19%)
Query: 104 DPISKRKVLNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFK 163
D +K +E + E+GHG G V AR +T+++VAIK K S K
Sbjct: 16 DLFNKHDPEKIFEDLREIGHGSFGAVYYARCNLTREIVAIK------------KMSYTGK 63
Query: 164 TPQSGIEDEKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDV 223
Q +D I +EI +++ +H + ++ + +LV+EYC D+
Sbjct: 64 QSQEKWQD--ILKEIRFLRQLNHPNTIEYKGCY--LRESTAWLVMEYCVGSA-----SDI 114
Query: 224 IETKARGPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGV 283
IE + L I GVL GL YLH G IHRDIK N+LL+++G+VK++DFG
Sbjct: 115 IEVHKKP---LHEDEIAAICLGVLSGLSYLHSLGRIHRDIKAGNILLTDNGVVKLADFG- 170
Query: 284 XXXXXXXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIW 343
GTP + APE+ L D E D+W
Sbjct: 171 ----------SAAIKCPANSFVGTPYWMAPEVILAMD------------EGQYDGKVDVW 208
Query: 344 AMGIT 348
++GIT
Sbjct: 209 SLGIT 213
>Hs20428779_1 [T] KOG0587 Traf2- and Nck-interacting kinase and related germinal
center kinase (GCK) family protein kinases
Length = 357
Score = 89.0 bits (219), Expect = 4e-17
Identities = 77/267 (28%), Positives = 124/267 (45%), Gaps = 43/267 (16%)
Query: 113 NTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIEDE 172
+T+EIIE +G G +GKV + L A+KI++ P S + DE
Sbjct: 25 DTWEIIETIGKGTYGKVYKVTNKRDGSLAAVKILD-----------------PVSDM-DE 66
Query: 173 KIKREIAIMKKC-HHEHVVKLIEVL---DDAKSRKIYLVLEYCSKGEIKWCPGDVIETKA 228
+I+ E I++ +H +VVK + D +++LVLE C+ G + ++++
Sbjct: 67 EIEAEYNILQFLPNHPNVVKFYGMFYKADHCVGGQLWLVLELCNGGSVT----ELVKGLL 122
Query: 229 RGPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXXXXX 288
R L I G LLGL++LH IIHRD+K N+LL+ +G VK+ DFGV
Sbjct: 123 RCGQRLDEAMISYILYGALLGLQHLHNNRIIHRDVKGNNILLTTEGGVKLVDFGVSAQLT 182
Query: 289 XXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGIT 348
+ GTP + APE+ E +++D +++ D+W++GIT
Sbjct: 183 STRLRRNT-------SVGTPFWMAPEVIACE---QQYDSSYDAR-------CDVWSLGIT 225
Query: 349 LHCLLFGMLPFISDYELELFDKIVNEP 375
L G P + ++ KI P
Sbjct: 226 AIELGDGDPPLFDMHPVKTLFKIPRNP 252
>HsM4758524 [T] KOG0587 Traf2- and Nck-interacting kinase and related germinal
center kinase (GCK) family protein kinases
Length = 1165
Score = 88.6 bits (218), Expect = 5e-17
Identities = 75/281 (26%), Positives = 124/281 (43%), Gaps = 48/281 (17%)
Query: 101 LEYDPISKRKVLNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSN 160
++ D S R +E++E +G+G +G+V R + T QL AIK+++ +
Sbjct: 11 VDIDLSSLRDPAGIFELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTED--------- 61
Query: 161 RFKTPQSGIEDEKIKREIAIMKK-CHHEHVVK----LIEVLDDAKSRKIYLVLEYCSKGE 215
E+E+IK EI ++KK HH ++ I+ +++LV+E+C G
Sbjct: 62 ---------EEEEIKLEINMLKKYSHHRNIATYYGAFIKKSPPGHDDQLWLVMEFCGAGS 112
Query: 216 IKWCPGDVIE-TKARGPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDG 274
I D+++ TK L I R +L GL +LH +IHRDIK N+LL+E+
Sbjct: 113 IT----DLVKNTKGN---TLKEDWIAYISREILRGLAHLHIHHVIHRDIKGQNVLLTENA 165
Query: 275 IVKISDFGVXXXXXXXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEP 334
VK+ DFGV GTP + APE+ ++ + +
Sbjct: 166 EVKLVDFGVSAQLDRTVGRRNTF-------IGTPYWMAPEVIACDE----------NPDA 208
Query: 335 IISFPTDIWAMGITLHCLLFGMLPFISDYELELFDKIVNEP 375
+ +D+W+ GIT + G P + + I P
Sbjct: 209 TYDYRSDLWSCGITAIEMAEGAPPLCDMHPMRALFLIPRNP 249
>Hs22035606 [T] KOG0587 Traf2- and Nck-interacting kinase and related germinal
center kinase (GCK) family protein kinases
Length = 1212
Score = 88.6 bits (218), Expect = 5e-17
Identities = 75/281 (26%), Positives = 124/281 (43%), Gaps = 48/281 (17%)
Query: 101 LEYDPISKRKVLNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSN 160
++ D S R +E++E +G+G +G+V R + T QL AIK+++ +
Sbjct: 11 VDIDLSSLRDPAGIFELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTED--------- 61
Query: 161 RFKTPQSGIEDEKIKREIAIMKK-CHHEHVVK----LIEVLDDAKSRKIYLVLEYCSKGE 215
E+E+IK EI ++KK HH ++ I+ +++LV+E+C G
Sbjct: 62 ---------EEEEIKLEINMLKKYSHHRNIATYYGAFIKKSPPGHDDQLWLVMEFCGAGS 112
Query: 216 IKWCPGDVIE-TKARGPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDG 274
I D+++ TK L I R +L GL +LH +IHRDIK N+LL+E+
Sbjct: 113 IT----DLVKNTKGN---TLKEDWIAYISREILRGLAHLHIHHVIHRDIKGQNVLLTENA 165
Query: 275 IVKISDFGVXXXXXXXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEP 334
VK+ DFGV GTP + APE+ ++ + +
Sbjct: 166 EVKLVDFGVSAQLDRTVGRRNTF-------IGTPYWMAPEVIACDE----------NPDA 208
Query: 335 IISFPTDIWAMGITLHCLLFGMLPFISDYELELFDKIVNEP 375
+ +D+W+ GIT + G P + + I P
Sbjct: 209 TYDYRSDLWSCGITAIEMAEGAPPLCDMHPMRALFLIPRNP 249
>Hs22035604 [T] KOG0587 Traf2- and Nck-interacting kinase and related germinal
center kinase (GCK) family protein kinases
Length = 1320
Score = 88.6 bits (218), Expect = 5e-17
Identities = 75/281 (26%), Positives = 124/281 (43%), Gaps = 48/281 (17%)
Query: 101 LEYDPISKRKVLNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSN 160
++ D S R +E++E +G+G +G+V R + T QL AIK+++ +
Sbjct: 11 VDIDLSSLRDPAGIFELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTED--------- 61
Query: 161 RFKTPQSGIEDEKIKREIAIMKK-CHHEHVVK----LIEVLDDAKSRKIYLVLEYCSKGE 215
E+E+IK EI ++KK HH ++ I+ +++LV+E+C G
Sbjct: 62 ---------EEEEIKLEINMLKKYSHHRNIATYYGAFIKKSPPGHDDQLWLVMEFCGAGS 112
Query: 216 IKWCPGDVIE-TKARGPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDG 274
I D+++ TK L I R +L GL +LH +IHRDIK N+LL+E+
Sbjct: 113 IT----DLVKNTKGN---TLKEDWIAYISREILRGLAHLHIHHVIHRDIKGQNVLLTENA 165
Query: 275 IVKISDFGVXXXXXXXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEP 334
VK+ DFGV GTP + APE+ ++ + +
Sbjct: 166 EVKLVDFGVSAQLDRTVGRRNTF-------IGTPYWMAPEVIACDE----------NPDA 208
Query: 335 IISFPTDIWAMGITLHCLLFGMLPFISDYELELFDKIVNEP 375
+ +D+W+ GIT + G P + + I P
Sbjct: 209 TYDYRSDLWSCGITAIEMAEGAPPLCDMHPMRALFLIPRNP 249
>Hs22035602 [T] KOG0587 Traf2- and Nck-interacting kinase and related germinal
center kinase (GCK) family protein kinases
Length = 1166
Score = 88.6 bits (218), Expect = 5e-17
Identities = 75/281 (26%), Positives = 124/281 (43%), Gaps = 48/281 (17%)
Query: 101 LEYDPISKRKVLNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSN 160
++ D S R +E++E +G+G +G+V R + T QL AIK+++ +
Sbjct: 11 VDIDLSSLRDPAGIFELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTED--------- 61
Query: 161 RFKTPQSGIEDEKIKREIAIMKK-CHHEHVVK----LIEVLDDAKSRKIYLVLEYCSKGE 215
E+E+IK EI ++KK HH ++ I+ +++LV+E+C G
Sbjct: 62 ---------EEEEIKLEINMLKKYSHHRNIATYYGAFIKKSPPGHDDQLWLVMEFCGAGS 112
Query: 216 IKWCPGDVIE-TKARGPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDG 274
I D+++ TK L I R +L GL +LH +IHRDIK N+LL+E+
Sbjct: 113 IT----DLVKNTKGN---TLKEDWIAYISREILRGLAHLHIHHVIHRDIKGQNVLLTENA 165
Query: 275 IVKISDFGVXXXXXXXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEP 334
VK+ DFGV GTP + APE+ ++ + +
Sbjct: 166 EVKLVDFGVSAQLDRTVGRRNTF-------IGTPYWMAPEVIACDE----------NPDA 208
Query: 335 IISFPTDIWAMGITLHCLLFGMLPFISDYELELFDKIVNEP 375
+ +D+W+ GIT + G P + + I P
Sbjct: 209 TYDYRSDLWSCGITAIEMAEGAPPLCDMHPMRALFLIPRNP 249
>Hs21361643 [T] KOG4717 Serine/threonine protein kinase
Length = 765
Score = 88.6 bits (218), Expect = 5e-17
Identities = 79/320 (24%), Positives = 139/320 (42%), Gaps = 62/320 (19%)
Query: 110 KVLNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGI 169
K+ Y++ + LG G VKLAR + T + VA+K++++ K T +
Sbjct: 11 KIAGLYDLDKTLGRGHFAVVKLARHVFTGEKVAVKVIDKTKLDT---------------L 55
Query: 170 EDEKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKAR 229
+ +E+ MK H ++V+L EV+D K+YL+LE +G++ D I
Sbjct: 56 ATGHLFQEVRCMKLVQHPNIVRLYEVID--TQTKLYLILELGDEGDM----FDYIMKHEE 109
Query: 230 GPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSE-DGIVKISDFGVXXXXX 288
G L+ ++ F ++ + Y H ++HRD+KP N++ E G+VK++DFG
Sbjct: 110 G---LNEDLPKKYFAQIVHAISYCHKLHVVHRDLKPENVVFFEKQGLVKLTDFGFSNKFQ 166
Query: 289 XXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGIT 348
+ G+ A+ APEI L ++ +D DIW++G+
Sbjct: 167 PGKKLTT--------SCGSLAYSAPEILLGDE----YDAP----------AVDIWSLGVI 204
Query: 349 LHCLLFGMLPFISDYELELFDKIVNEPLVFEPYQKIEQCQVSQVECKEEYEEAQXXXXXX 408
L L+ G PF + E I++ + VS+ ECK+
Sbjct: 205 LFMLVCGQPPFQEANDSETLTMIMDCKYTVPSH-------VSK-ECKD-------LITRM 249
Query: 409 XXXXXXXRMAIQDAKKHPWV 428
R ++++ + HPW+
Sbjct: 250 LQRDPKRRASLEEIENHPWL 269
>Hs20070158 [T] KOG0201 Serine/threonine protein kinase
Length = 443
Score = 88.6 bits (218), Expect = 5e-17
Identities = 69/231 (29%), Positives = 104/231 (44%), Gaps = 49/231 (21%)
Query: 118 IEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIEDEKIKRE 177
+E++G G G+V D T+++VAIKI++ + E E I++E
Sbjct: 39 LEKIGKGSFGEVFKGIDNRTQKVVAIKIIDLEEAED----------------EIEDIQQE 82
Query: 178 IAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKARGPPLLSFQ 237
I ++ +C +V K K K+++++EY G D++E P L
Sbjct: 83 ITVLSQCDSPYVTKYYGSY--LKDTKLWIIMEYLGGGSAL----DLLE-----PGPLDET 131
Query: 238 RTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXXXXXXXXXXXXXX 297
+ I R +L GL+YLH + IHRDIK AN+LLSE G VK++DFGV
Sbjct: 132 QIATILREILKGLDYLHSEKKIHRDIKAANVLLSEHGEVKLADFGVAGQLTDTQIKRNTF 191
Query: 298 XXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGIT 348
GTP + APE+ K+ DIW++GIT
Sbjct: 192 -------VGTPFWMAPEVI---------------KQSAYDSKADIWSLGIT 220
>SPCC320.12c [D] KOG0580 Serine/threonine protein kinase
Length = 384
Score = 88.2 bits (217), Expect = 6e-17
Identities = 77/317 (24%), Positives = 134/317 (41%), Gaps = 62/317 (19%)
Query: 112 LNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIED 171
+ +EI + LG G+ G+V LA++ T +VA+K + HK K +
Sbjct: 115 IGMFEIGKPLGKGKFGRVYLAKEKKTGFIVALKTL--HKSELVQSKI------------E 160
Query: 172 EKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKARGP 231
++++REI I H+++++L D K +IYL+LE+ +GE+ + R
Sbjct: 161 KQVRREIEIQSNLRHKNILRLYGHFHDEK--RIYLILEFAGRGEL-------YQHLRRAK 211
Query: 232 PLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXXXXXXXX 291
++ IF+ + L YLH + +IHRDIKP N+LL DG +K+SDFG
Sbjct: 212 RFSEEVASKYIFQ-MANALSYLHKKHVIHRDIKPENILLGIDGEIKLSDFGWSVHAPSNR 270
Query: 292 XXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGITLHC 351
GT + PE+ ++ +K DL W++G+ +
Sbjct: 271 RTTL---------CGTLDYLPPEMVEGKEHTEKVDL---------------WSLGVLTYE 306
Query: 352 LLFGMLPFISDYELELFDKIVNEPLVFEPYQKIEQCQVSQVECKEEYEEAQXXXXXXXXX 411
L G PF + + ++ K++ S V +A+
Sbjct: 307 FLVGAPPF---------EDMSGHSATYKRIAKVDLKIPSFVP-----PDARDLISRLLQH 352
Query: 412 XXXXRMAIQDAKKHPWV 428
RM+++ +HPW+
Sbjct: 353 NPEKRMSLEQVMRHPWI 369
>At5g50860 [D] KOG0600 Cdc2-related protein kinase
Length = 580
Score = 88.2 bits (217), Expect = 6e-17
Identities = 56/173 (32%), Positives = 93/173 (53%), Gaps = 29/173 (16%)
Query: 114 TYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIEDEK 173
TYE +E++G G + V A+DL++ ++VA+K V +F N +E E
Sbjct: 113 TYEKLEKIGQGTYSNVYKAKDLLSGKIVALKKV----------RFDN--------LEAES 154
Query: 174 IK---REIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKARG 230
+K REI ++++ +H +V+KL ++ S +YLV EY D+ A
Sbjct: 155 VKFMAREILVLRRLNHPNVIKLQGLVTSRVSCSLYLVFEYMEH--------DLSGLAATQ 206
Query: 231 PPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGV 283
+ + + +L GLE+ H +G++HRDIK +NLL+ DGI+KI+DFG+
Sbjct: 207 GLKFDLPQVKCFMKQLLSGLEHCHSRGVLHRDIKGSNLLIDNDGILKIADFGL 259
>7292249 [T] KOG0587 Traf2- and Nck-interacting kinase and related germinal
center kinase (GCK) family protein kinases
Length = 979
Score = 88.2 bits (217), Expect = 6e-17
Identities = 69/240 (28%), Positives = 114/240 (46%), Gaps = 48/240 (20%)
Query: 115 YEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIEDEKI 174
+E+IE +G+G +G+V R T QL AIK+++ + E+E+I
Sbjct: 32 FELIEVVGNGTYGQVYKGRHTKTGQLAAIKVMDVTED------------------EEEEI 73
Query: 175 KREIAIMKK-CHHEHVVK----LIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIE-TKA 228
K EI ++KK +H ++ I+ K +++LV+EYC G + D+++ TK
Sbjct: 74 KLEINVLKKYSNHRNIATYYGAFIKKSPPGKDDQLWLVMEYCGAGSVT----DLVKSTKG 129
Query: 229 RGPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXXXXX 288
+ L + I R +L GL YLH +IHRDIK N+LL+++ VK+ DFGV
Sbjct: 130 QS---LKEEWIAYICREILRGLSYLHSNKVIHRDIKGQNVLLTDNAEVKLVDFGVSAQLD 186
Query: 289 XXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGIT 348
GTP + APE+ ++ + + +D+W++GIT
Sbjct: 187 RTIGRRNTF-------IGTPYWMAPEVIACDE----------NPDATYDNRSDLWSLGIT 229
>Hs4557511 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 454
Score = 87.8 bits (216), Expect = 8e-17
Identities = 69/261 (26%), Positives = 116/261 (44%), Gaps = 48/261 (18%)
Query: 115 YEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIEDEKI 174
YE+ EELG GQ V+ R T + A K + KKR R + + G+ E+I
Sbjct: 13 YEMGEELGSGQFAIVRKCRQKGTGKEYAAKFI---KKR--------RLSSSRRGVSREEI 61
Query: 175 KREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKARGPPLL 234
+RE+ I+++ H +++ L ++ ++ + L+LE S GE+ D + K L
Sbjct: 62 EREVNILREIRHPNIITLHDIFENKTD--VVLILELVSGGELF----DFLAEKES----L 111
Query: 235 SFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGI----VKISDFGVXXXXXXX 290
+ + + +L G+ YLH + I H D+KP N++L + + +K+ DFG+
Sbjct: 112 TEDEATQFLKQILDGVHYLHSKRIAHFDLKPENIMLLDKNVPNPRIKLIDFGI------- 164
Query: 291 XXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGITLH 350
GTP F APEI E + D+W++G+ +
Sbjct: 165 -AHKIEAGNEFKNIFGTPEFVAPEIVNYEP---------------LGLEADMWSIGVITY 208
Query: 351 CLLFGMLPFISDYELELFDKI 371
LL G PF+ + + E I
Sbjct: 209 ILLSGASPFLGETKQETLTNI 229
>Hs20543401 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 2092
Score = 87.8 bits (216), Expect = 8e-17
Identities = 72/270 (26%), Positives = 115/270 (41%), Gaps = 47/270 (17%)
Query: 115 YEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIEDEKI 174
+E I+ + +G +G V R ++Q A+K +N+ N I+ +
Sbjct: 39 FETIKLISNGAYGAVYFVRHKESRQRFAMKKINKQNLILRNQ------------IQQAFV 86
Query: 175 KREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKARGPPLL 234
+R+I + + VV + + R + +V+EY G+ K GP L
Sbjct: 87 ERDILTFAE--NPFVVSMYCSFETR--RHLCMVMEYVEGGDCATL------MKNMGP--L 134
Query: 235 SFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXXXXXXXXXX- 293
R F +L LEYLH GI+HRD+KP NLL++ G +K++DFG+
Sbjct: 135 PVDMARMYFAETVLALEYLHNYGIVHRDLKPDNLLVTSMGHIKLTDFGLSKVGLMSMTTN 194
Query: 294 -------XXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMG 346
+ GTP + APE+ L + K P D WAMG
Sbjct: 195 LYEGHIEKDAREFLDKQVCGTPEYIAPEVILRQGYGK---------------PVDWWAMG 239
Query: 347 ITLHCLLFGMLPFISDYELELFDKIVNEPL 376
I L+ L G +PF D ELF +++++ +
Sbjct: 240 IILYEFLVGCVPFFGDTPEELFGQVISDEI 269
>7296450 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 769
Score = 87.8 bits (216), Expect = 8e-17
Identities = 75/276 (27%), Positives = 112/276 (40%), Gaps = 45/276 (16%)
Query: 110 KVLNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGI 169
+ + YE+ LG G V AR L T Q VAIK+++ KK +NR
Sbjct: 9 ETIEDYEVQHLLGKGGFATVYKARCLHTHQDVAIKMID--KKLIQGTGLTNR-------- 58
Query: 170 EDEKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKAR 229
+++E+ I + H V++L DA +YLVLE GE+ +
Sbjct: 59 ----VRQEVEIHSRLKHPSVLQLYTFFQDANY--VYLVLELAHNGELHRYMNHIARP--- 109
Query: 230 GPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXXXXXX 289
+ I + V+ GL YLH I+HRDI +NLLLS + VKI+DFG+
Sbjct: 110 ----FTETEAASILKQVVAGLLYLHSHNIMHRDISLSNLLLSREMHVKIADFGLATQLKR 165
Query: 290 XXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGITL 349
GTP + +PE+ P D+W++G L
Sbjct: 166 PDERHMT-------MCGTPNYISPEVV---------------SRTSHGLPADVWSVGCML 203
Query: 350 HCLLFGMLPFISDYELELFDKIVNEPLVFEPYQKIE 385
+ LL G PF +D +K+V + + E
Sbjct: 204 YTLLVGRPPFETDAVQSTLNKVVMSEYIMPAHLSYE 239
>Hs4502567_1 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 360
Score = 87.8 bits (216), Expect = 8e-17
Identities = 84/319 (26%), Positives = 124/319 (38%), Gaps = 55/319 (17%)
Query: 113 NTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIEDE 172
+ YE+ E +G G V+ + T Q A+KIV+ K T G+ E
Sbjct: 10 DVYELCEVIGKGPFSVVRRCINRETGQQFAVKIVDVAKF------------TSSPGLSTE 57
Query: 173 KIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKARGPP 232
+KRE +I H H+V+L+E + +Y+V E+ ++ + I +A
Sbjct: 58 DLKREASICHMLKHPHIVELLETY--SSDGMLYMVFEFMDGADLCF----EIVKRADAGF 111
Query: 233 LLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLS---EDGIVKISDFGVXXXXXX 289
+ S R +L L Y H IIHRD+KP +LL+ VK+ FGV
Sbjct: 112 VYSEAVASHYMRQILEALRYCHDNNIIHRDVKPHCVLLASKENSAPVKLGGFGV------ 165
Query: 290 XXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGITL 349
GTP F APE+ +K+ +P K P D+W G+ L
Sbjct: 166 -AIQLGESGLVAGGRVGTPHFMAPEV------VKR---EPYGK------PVDVWGCGVIL 209
Query: 350 HCLLFGMLPFISDYELELFDKIVNEPLVFEPYQKIEQCQVSQVECKEEYEEAQXXXXXXX 409
LL G LPF E LF+ I+ P Q E A+
Sbjct: 210 FILLSGCLPFYGTKE-RLFEGIIKGKYKMNPRQ-----------WSHISESAKDLVRRML 257
Query: 410 XXXXXXRMAIQDAKKHPWV 428
R+ + +A HPW+
Sbjct: 258 MLDPAERITVYEALNHPWL 276
>SPAC890.03 [T] KOG0583 Serine/threonine protein kinase
Length = 672
Score = 87.4 bits (215), Expect = 1e-16
Identities = 79/286 (27%), Positives = 115/286 (39%), Gaps = 51/286 (17%)
Query: 112 LNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIED 171
+ TY I +G G GKV LA L+T V +K R +
Sbjct: 28 VGTYRIESVVGEGSFGKVYLAAHLLTNTKVVLKSSCRKQAII------------------ 69
Query: 172 EKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKARGP 231
+ REI ++ H ++ +L EV+ +IYL +EYC GE+ D + + R
Sbjct: 70 --LAREIHHHRRLLHPNITRLYEVV--CTEDRIYLAMEYCPNGELY----DWVAREKR-- 119
Query: 232 PLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXXXXXXXX 291
L + T I + ++YLH QG +HRD+K N+ L + VK+ DFG
Sbjct: 120 --LDEKTTCRIMWQLCCAIQYLHRQGCVHRDLKLENIFLDKAYNVKLGDFGFSRDSDCSR 177
Query: 292 XXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGITLHC 351
GT A+ APE+ I DIW++GI ++
Sbjct: 178 RTFMNT------RCGTVAYCAPELV--------------QGHKYIGECVDIWSLGIIMYA 217
Query: 352 LLFGMLPFISDYELELFDKIVNE-PLVFEPYQKIEQCQVSQVECKE 396
LL G LPF D KI+NE P E K + + CK+
Sbjct: 218 LLIGRLPFDEDDVSLTEQKIINECPQYPETLSKNSSSLLKSLLCKD 263
>Hs7706401 [T] KOG0577 Serine/threonine protein kinase
Length = 1235
Score = 87.4 bits (215), Expect = 1e-16
Identities = 67/231 (29%), Positives = 102/231 (44%), Gaps = 47/231 (20%)
Query: 118 IEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIEDEKIKRE 177
+ E+GHG G V ARD+ ++VAIK K +++ K SN + + I +E
Sbjct: 31 LREIGHGSFGAVYFARDVRNSEVVAIK------KMSYSGKQSNE--------KWQDIIKE 76
Query: 178 IAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKARGPPLLSFQ 237
+ ++K H + ++ + +LV+EYC D++E + PL +
Sbjct: 77 VRFLQKLRHPNTIQYRGCY--LREHTAWLVMEYCLGSA-----SDLLEVHKK--PLQEVE 127
Query: 238 RTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXXXXXXXXXXXXXX 297
+ G L GL YLH +IHRD+K N+LLSE G+VK+ DFG
Sbjct: 128 -IAAVTHGALQGLAYLHSHNMIHRDVKAGNILLSEPGLVKLGDFG-----------SASI 175
Query: 298 XXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGIT 348
GTP + APE+ L D E D+W++GIT
Sbjct: 176 MAPANSFVGTPYWMAPEVILAMD------------EGQYDGKVDVWSLGIT 214
>Hs6005810 [T] KOG0576 Mitogen-activated protein kinase kinase kinase kinase
(MAP4K) germinal center kinase family
Length = 833
Score = 87.4 bits (215), Expect = 1e-16
Identities = 74/246 (30%), Positives = 115/246 (46%), Gaps = 47/246 (19%)
Query: 104 DP-ISKRKVLNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRF 162
DP I R + Y++++ LG G +G+V ARD V+ LVA+K+V K +D S
Sbjct: 5 DPDIFNRDPRDHYDLLQRLGGGTYGEVFKARDKVSGDLVALKMV----KMEPDDDVST-- 58
Query: 163 KTPQSGIEDEKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGD 222
+++EI I+K C H ++V +K+++ +E+C G ++ D
Sbjct: 59 -----------LQKEILILKTCRHANIVAYHGSY--LWLQKLWICMEFCGAGSLQ----D 101
Query: 223 VIETKARGPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFG 282
+ + LS + + R VL GL YLH Q IHRDIK AN+L+++ G V+++DFG
Sbjct: 102 IYQVTGS----LSELQISYVCREVLQGLAYLHSQKKIHRDIKGANILINDAGEVRLADFG 157
Query: 283 VXXXXXXXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDI 342
+ GTP + APE+ V L E DI
Sbjct: 158 ISAQIGATLARRLSF-------IGTPYWMAPEVAAVA-------LKGGYNE-----LCDI 198
Query: 343 WAMGIT 348
W++GIT
Sbjct: 199 WSLGIT 204
>Hs4759208 [T] KOG0577 Serine/threonine protein kinase
Length = 1049
Score = 87.4 bits (215), Expect = 1e-16
Identities = 67/231 (29%), Positives = 102/231 (44%), Gaps = 47/231 (20%)
Query: 118 IEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIEDEKIKRE 177
+ E+GHG G V ARD+ ++VAIK K +++ K SN + + I +E
Sbjct: 31 LREIGHGSFGAVYFARDVRNSEVVAIK------KMSYSGKQSNE--------KWQDIIKE 76
Query: 178 IAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKARGPPLLSFQ 237
+ ++K H + ++ + +LV+EYC D++E + PL +
Sbjct: 77 VRFLQKLRHPNTIQYRGCY--LREHTAWLVMEYCLGSA-----SDLLEVHKK--PLQEVE 127
Query: 238 RTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXXXXXXXXXXXXXX 297
+ G L GL YLH +IHRD+K N+LLSE G+VK+ DFG
Sbjct: 128 -IAAVTHGALQGLAYLHSHNMIHRDVKAGNILLSEPGLVKLGDFG-----------SASI 175
Query: 298 XXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGIT 348
GTP + APE+ L D E D+W++GIT
Sbjct: 176 MAPANSFVGTPYWMAPEVILAMD------------EGQYDGKVDVWSLGIT 214
>Hs22057171 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 456
Score = 87.4 bits (215), Expect = 1e-16
Identities = 82/327 (25%), Positives = 139/327 (42%), Gaps = 66/327 (20%)
Query: 122 GHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIEDEKIKREIAIM 181
G G+ G+V + T +A KI+ K R DK E++K EI++M
Sbjct: 181 GRGRFGQVHKCEETATGLKLAAKII---KTRGMKDK--------------EEVKNEISVM 223
Query: 182 KKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKARGPPLLSFQRTRE 241
+ H ++++L + + I LV+EY GE+ D I ++ L+ T
Sbjct: 224 NQLDHANLIQLYDAFESKND--IVLVMEYVDGGELF----DRIIDESYN---LTELDTIL 274
Query: 242 IFRGVLLGLEYLHFQGIIHRDIKPANLL-LSEDGI-VKISDFGVXXXXXXXXXXXXXXXX 299
+ + G+ ++H I+H D+KP N+L ++ D +KI DFG+
Sbjct: 275 FMKQICEGIRHMHQMYILHLDLKPENILCVNRDAKQIKIIDFGLARRYKPREKLKVNF-- 332
Query: 300 XXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGITLHCLLFGMLPF 359
GTP F APE+ + +SFPTD+W++G+ + LL G+ PF
Sbjct: 333 ------GTPEFLAPEVVNYD---------------FVSFPTDMWSVGVIAYMLLSGLSPF 371
Query: 360 ISDYELELFDKIV--NEPLVFEPYQKIEQCQVSQVECKEEYEEAQXXXXXXXXXXXXXRM 417
+ D + E + I+ L E +Q I EEA+ R+
Sbjct: 372 LGDNDAETLNNILACRWDLEDEEFQDIS-------------EEAKEFISKLLIKEKSWRI 418
Query: 418 AIQDAKKHPWVCWDFNHNDYMSDQEKS 444
+ +A KHPW+ H+ + ++K+
Sbjct: 419 SASEALKHPWLSDHKLHSRLNAQKKKN 445
>CE26076 [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 503
Score = 87.4 bits (215), Expect = 1e-16
Identities = 78/278 (28%), Positives = 127/278 (45%), Gaps = 52/278 (18%)
Query: 115 YEIIEELGHGQHGKVKLARDLVTKQLVAI--KIVNRHKKRTFNDKFSNRFKTPQSGIEDE 172
Y +++ LG G G+V L + ++ A KI +K + F D
Sbjct: 24 YRVVQTLGEGAFGEVLLIVNTKNPEVAAAMKKINIANKSKDFIDN--------------- 68
Query: 173 KIKREIAIMKKCH---HEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKAR 229
I++E + K+ H++V+++I + +D + YL LEY GE+ D IE
Sbjct: 69 -IRKEYLLQKRVSAVGHDNVIRMIGMRNDPQF--YYLFLEYADGGELF----DKIEPDCG 121
Query: 230 GPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXXXXXX 289
P+ + + F+ ++ GL+++H ++HRDIKP NLLL+ ++KISDFG+
Sbjct: 122 MSPVFA----QFYFKQLICGLKFIHDNDVVHRDIKPENLLLTGTHVLKISDFGMATLYRN 177
Query: 290 XXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGITL 349
+ GT + APE+C KK+ + P P D+W+ GI L
Sbjct: 178 KGEERLLDL-----SCGTIPYAAPELC----AGKKY------RGP----PVDVWSSGIVL 218
Query: 350 HCLLFGMLPF--ISDYELELFDKIVNEPLVFEPYQKIE 385
+L G LP+ SD I N L P++KI+
Sbjct: 219 IAMLTGELPWDRASDASQSYMGWISNTSLDERPWKKID 256
>CE04603 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 371
Score = 87.4 bits (215), Expect = 1e-16
Identities = 70/284 (24%), Positives = 117/284 (40%), Gaps = 49/284 (17%)
Query: 95 ETNTVSLEYDPISKRKVLNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTF 154
E + L P + L+ E I +G G G+V+LARD +T A+K++N +
Sbjct: 43 EETHMKLSITPTRESFSLSQLERIITIGKGTFGRVELARDKITGAHYALKVLNIRRVVDM 102
Query: 155 NDKFSNRFKTPQSGIEDEKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKG 214
+ + + E ++ + H +VK+ D S +Y+++E+
Sbjct: 103 R--------------QTQHVHNEKRVLLQLKHPFIVKMYASEKD--SNHLYMIMEFV--- 143
Query: 215 EIKWCPGDVIETKARGPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDG 274
PG + + R S R ++ LEY+H GI++RD+KP NL+LS++G
Sbjct: 144 -----PGGEMFSYLRASRSFSNSMARFYASEIVCALEYIHSLGIVYRDLKPENLMLSKEG 198
Query: 275 IVKISDFGVXXXXXXXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEP 334
+K++DFG GTP + APE K
Sbjct: 199 HIKMADFGFAKELRDRTYT----------ICGTPDYLAPESLARTGHNK----------- 237
Query: 335 IISFPTDIWAMGITLHCLLFGMLPFISDYELELFDKIVNEPLVF 378
D WA+GI ++ ++ G PF E++D I+ L F
Sbjct: 238 ----GVDWWALGILIYEMMVGKPPFRGKTTSEIYDAIIEHKLKF 277
>At1g03740 [D] KOG0600 Cdc2-related protein kinase
Length = 542
Score = 87.4 bits (215), Expect = 1e-16
Identities = 55/171 (32%), Positives = 92/171 (53%), Gaps = 23/171 (13%)
Query: 113 NTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIEDE 172
NT+E +E++G G + V ARDL+ ++VA+K V + ND S +F
Sbjct: 211 NTFEKLEKIGQGTYSSVYRARDLLHNKIVALKKV----RFDLNDMESVKF---------- 256
Query: 173 KIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKARGPP 232
+ REI +M++ H +V+KL ++ S +YLV EY D++ +
Sbjct: 257 -MAREIIVMRRLDHPNVLKLEGLITAPVSSSLYLVFEYMDH--------DLLGLSSLPGV 307
Query: 233 LLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGV 283
+ + + R +L GLE+ H +G++HRDIK +NLL+ G++KI+DFG+
Sbjct: 308 KFTEPQVKCYMRQLLSGLEHCHSRGVLHRDIKGSNLLIDSKGVLKIADFGL 358
>Hs5174701 [T] KOG0579 Ste20-like serine/threonine protein kinase
Length = 968
Score = 87.0 bits (214), Expect = 1e-16
Identities = 69/252 (27%), Positives = 114/252 (44%), Gaps = 46/252 (18%)
Query: 100 SLEYDPISKRKVLN-TYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKF 158
S EY+ + + N +EI+ ELG G GKV A++ T L A K++ + D
Sbjct: 20 SREYEHVRRDLDPNEVWEIVGELGDGAFGKVYKAKNKETGALAAAKVIETKSEEELEDYI 79
Query: 159 SNRFKTPQSGIEDEKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKW 218
EI I+ C H ++VKL+ K+++++E+C G +
Sbjct: 80 V-----------------EIEILATCDHPYIVKLLGAY--YHDGKLWIMIEFCPGGAV-- 118
Query: 219 CPGDVIETKA-RGPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVK 277
D I + RG L+ + + + R +L L +LH + IIHRD+K N+L++ +G ++
Sbjct: 119 ---DAIMLELDRG---LTEPQIQVVCRQMLEALNFLHSKRIIHRDLKAGNVLMTLEGDIR 172
Query: 278 ISDFGVXXXXXXXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIIS 337
++DFGV GTP + APE+ + E K+
Sbjct: 173 LADFGVSAKNLKTLQKRDSF-------IGTPYWMAPEVVMCE----------TMKDTPYD 215
Query: 338 FPTDIWAMGITL 349
+ DIW++GITL
Sbjct: 216 YKADIWSLGITL 227
>At3g17850 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 1263
Score = 87.0 bits (214), Expect = 1e-16
Identities = 79/311 (25%), Positives = 128/311 (40%), Gaps = 65/311 (20%)
Query: 92 PVKETNTVSLEYDPISKRK--VLNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRH 149
P+++ SL P+ R ++ +EII+ + G G+V LA+ T L AIK++
Sbjct: 865 PLEDDVVRSLRTSPVHPRDRTSIDDFEIIKPISRGAFGRVFLAKKRTTGDLFAIKVL--- 921
Query: 150 KKRTFNDKFSNRFKTPQSGIEDEKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLE 209
KK K + +E +R+I I + VV+ + +YLV+E
Sbjct: 922 KKADMIRK---------NAVESILAERDILI--NVRNPFVVRFFYSFTCRDN--LYLVME 968
Query: 210 YCSKGEIKWCPGDVIETKARGPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLL 269
Y + G++ + R L R V+L LEYLH +G++HRD+KP NLL
Sbjct: 969 YLNGGDLY--------SLLRNLGCLEEDIVRVYIAEVVLALEYLHSEGVVHRDLKPDNLL 1020
Query: 270 LSEDGIVKISDFGVXXXXXXXXXXXXXXXXXXA------------------------KTA 305
++ DG +K++DFG+
Sbjct: 1021 IAHDGHIKLTDFGLSKVGLINSTDDLAGPAVSGTSLLDEEESRLAASEEQLERRKKRSAV 1080
Query: 306 GTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGITLHCLLFGMLPFISDYEL 365
GTP + APEI L D W++GI L L+ G+ PF +++
Sbjct: 1081 GTPDYLAPEILLGTGH---------------GATADWWSVGIILFELIVGIPPFNAEHPQ 1125
Query: 366 ELFDKIVNEPL 376
++FD I+N +
Sbjct: 1126 QIFDNILNRKI 1136
>7303804 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 387
Score = 87.0 bits (214), Expect = 1e-16
Identities = 54/182 (29%), Positives = 97/182 (52%), Gaps = 23/182 (12%)
Query: 102 EYDPISKRKVLNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNR 161
E + + + ++ +E + +G G +G V ARD + ++VA+K V +++
Sbjct: 40 EQNLFGRCRPVSEFEKLNRVGEGSYGIVYRARDTRSNEIVALKKVRMDQEKD-------- 91
Query: 162 FKTPQSGIEDEKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPG 221
P SG+ REI I+K+CHHE++V+L EV+ I+LV+++C +
Sbjct: 92 -GLPISGL------REIMILKQCHHENIVRLREVVVGKSLDSIFLVMDFCEQ-------- 136
Query: 222 DVIETKARGPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDF 281
D+ + + I VL L+YLH + +IHRD+K +NLL+++ G +K++DF
Sbjct: 137 DLASVLDNMSQPFTESEVKCITLQVLKALKYLHSRFMIHRDLKVSNLLMTDKGCIKVADF 196
Query: 282 GV 283
G+
Sbjct: 197 GL 198
>7292679 [G] KOG0599 Phosphorylase kinase gamma subunit
Length = 560
Score = 87.0 bits (214), Expect = 1e-16
Identities = 75/253 (29%), Positives = 115/253 (44%), Gaps = 50/253 (19%)
Query: 115 YEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIED--- 171
YE E LG G V+ + T + A KI++ T +SG +
Sbjct: 23 YEPKEILGRGISSTVRRCIEKETGKEFAAKIIDLGA-------------TTESGETNPYH 69
Query: 172 --EKIKREIAIMKKCH-HEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKA 228
E ++EI+I+++ H +++ L +V + ++LV E C KGE+ V+
Sbjct: 70 MLEATRQEISILRQVMGHPYIIDLQDVFES--DAFVFLVFELCPKGELFDYLTSVVT--- 124
Query: 229 RGPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXXXXX 288
LS ++TR I R + G+EY+H + I+HRD+KP N+LL E+ VKI+DFG
Sbjct: 125 -----LSEKKTRTIMRQIFEGVEYIHAKSIVHRDLKPENILLDENHNVKITDFG------ 173
Query: 289 XXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIK--KFDLDPNSKEPIISFPTDIWAMG 346
GTP + APE T+K F+ P + + DIWA G
Sbjct: 174 --FAKQLQEGEKLTNLCGTPGYLAPE------TLKCNMFEGSPGYSQEV-----DIWACG 220
Query: 347 ITLHCLLFGMLPF 359
+ + LL G PF
Sbjct: 221 VIMFTLLVGCPPF 233
>Hs4507275 [D] KOG0580 Serine/threonine protein kinase
Length = 403
Score = 86.7 bits (213), Expect = 2e-16
Identities = 87/393 (22%), Positives = 156/393 (39%), Gaps = 67/393 (17%)
Query: 58 EKQRQRQLNHPLHQNHIRTVLGSHLNSGQRITYGPVK--ETNTVSLEYDPISKRK--VLN 113
+ Q+Q+QL + + L + S Q + P E S + + SK++ L
Sbjct: 72 QNQKQKQLQATSVPHPVSRPLNNTQKSKQPLPSAPENNPEEELASKQKNEESKKRQWALE 131
Query: 114 TYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIEDEK 173
+EI LG G+ G V LAR+ +K ++A+K++ + + ++G+E +
Sbjct: 132 DFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLE-------------KAGVEHQ- 177
Query: 174 IKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKARGPPL 233
++RE+ I H ++++L DA ++YL+LEY G + + +
Sbjct: 178 LRREVEIQSHLRHPNILRLYGYFHDAT--RVYLILEYAPLG--------TVYRELQKLSK 227
Query: 234 LSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXXXXXXXXXX 293
QRT + L Y H + +IHRDIKP NLLL G +KI+DFG
Sbjct: 228 FDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFG---------WS 278
Query: 294 XXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGITLHCLL 353
GT + PE ++E + D+W++G+ + L
Sbjct: 279 VHAPSSRRTTLCGTLDYLPPE--MIEGRMH-------------DEKVDLWSLGVLCYEFL 323
Query: 354 FGMLPFISDYELELFDKIVNEPLVFEPYQKIEQCQVSQVECKEEYEEAQXXXXXXXXXXX 413
G PF ++ E + +I F + E A+
Sbjct: 324 VGKPPFEANTYQETYKRISRVEFTFPDFVT---------------EGARDLISRLLKHNP 368
Query: 414 XXRMAIQDAKKHPWVCWDFNHNDYMSDQEKSLK 446
R +++ +HPW+ + + ++E + K
Sbjct: 369 SQRPMLREVLEHPWITANSSKPSNCQNKESASK 401
>Hs14776113 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 424
Score = 86.7 bits (213), Expect = 2e-16
Identities = 78/332 (23%), Positives = 135/332 (40%), Gaps = 70/332 (21%)
Query: 102 EYDPISKRKVLNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNR 161
++DP +V Y+I +G G +V T+Q AIK++ +
Sbjct: 89 KFDP----RVTAKYDIKALIGRGSFSRVVRVEHRATRQPYAIKMIETKYREG-------- 136
Query: 162 FKTPQSGIEDEKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPG 221
E + E+ ++++ H ++++L+EV + + ++Y+V+E + GE+
Sbjct: 137 ---------REVCESELRVLRRVRHANIIQLVEVFETQE--RVYMVMELATGGELF---- 181
Query: 222 DVIETKARGPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLL---SEDGIVKI 278
D I K + + + + VL G+ YLH GI HRD+KP NLL D + I
Sbjct: 182 DRIIAKGS----FTERDATRVLQMVLDGVRYLHALGITHRDLKPENLLYYHPGTDSKIII 237
Query: 279 SDFGVXXXXXXXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISF 338
+DFG+ T GTP + APE+ + ++P +
Sbjct: 238 TDFGLASARKKGDDCLMKT------TCGTPEYIAPEVLV--------------RKPYTN- 276
Query: 339 PTDIWAMGITLHCLLFGMLPFISDYELELFDKIVNEPLVF--EPYQKIEQCQVSQVECKE 396
D+WA+G+ + LL G +PF D L+ +I+ + EP+ +
Sbjct: 277 SVDMWALGVIAYILLSGTMPFEDDNRTRLYRQILRGKYSYSGEPWPSVSNL--------- 327
Query: 397 EYEEAQXXXXXXXXXXXXXRMAIQDAKKHPWV 428
A+ RM A +HPWV
Sbjct: 328 ----AKDFIDRLLTVDPGARMTALQALRHPWV 355
>At3g13530 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 1368
Score = 86.7 bits (213), Expect = 2e-16
Identities = 75/271 (27%), Positives = 126/271 (45%), Gaps = 52/271 (19%)
Query: 108 KRKVL-NTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQ 166
K K L N Y + +E+G G +G+V DL VAIK V+ +
Sbjct: 12 KSKTLDNKYMLGDEIGKGAYGRVYKGLDLENGDFVAIKQVSL-----------------E 54
Query: 167 SGIEDE--KIKREIAIMKKCHHEHVVKLIEVLDDAKSRK-IYLVLEYCSKGEIKWCPGDV 223
+ ++++ I +EI ++K +H+++VK L +K++ ++++LEY G + ++
Sbjct: 55 NIVQEDLNTIMQEIDLLKNLNHKNIVKY---LGSSKTKTHLHIILEYVENGSL----ANI 107
Query: 224 IETKARGPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGV 283
I+ GP S VL GL YLH QG+IHRDIK AN+L +++G+VK++DFGV
Sbjct: 108 IKPNKFGPFPESLVAV--YIAQVLEGLVYLHEQGVIHRDIKGANILTTKEGLVKLADFGV 165
Query: 284 XXXXXXXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIW 343
GTP + APE+ + + +DIW
Sbjct: 166 ATKLNEADVNTH-------SVVGTPYWMAPEVIEMSG---------------VCAASDIW 203
Query: 344 AMGITLHCLLFGMLPFISDYELELFDKIVNE 374
++G T+ LL + P+ + +IV +
Sbjct: 204 SVGCTVIELLTCVPPYYDLQPMPALFRIVQD 234
>At2g31500 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 582
Score = 86.7 bits (213), Expect = 2e-16
Identities = 109/481 (22%), Positives = 185/481 (37%), Gaps = 98/481 (20%)
Query: 115 YEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIEDEKI 174
Y++ +ELG G+ G ++ T++ A K +++ K RT I+ E +
Sbjct: 66 YDLGKELGRGEFGVTHECIEISTRERFACKRISKEKLRT--------------EIDVEDV 111
Query: 175 KREIAIMKKC-HHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKARGPPL 233
+RE+ IM+ H ++V E +D + +YLV+E C GE+ D I ++
Sbjct: 112 RREVEIMRCLPKHPNIVSFKEAFEDKDA--VYLVMEICEGGELF----DRIVSRGH---- 161
Query: 234 LSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLS---EDGIVKISDFGVXXXXXXX 290
+ + + + +L ++ H G+IHRD+KP N L S E +K DFG+
Sbjct: 162 YTERAAASVAKTILEVVKVCHEHGVIHRDLKPENFLFSNGTETAQLKAIDFGLSIFFKPA 221
Query: 291 XXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGITLH 350
+ G+P + APE+ L N I D+W+ G+ L+
Sbjct: 222 QRFN--------EIVGSPYYMAPEV-----------LRRNYGPEI-----DVWSAGVILY 257
Query: 351 CLLFGMLPFISDYELELFDKIVNEPLVFE--PYQKIEQCQVSQVECKEEYEEAQXXXXXX 408
LL G+ PF ++ E + IV + FE P+ K+ EA+
Sbjct: 258 ILLCGVPPFWAETEEGIAHAIVRGNIDFERDPWPKVS-------------HEAKELVKNM 304
Query: 409 XXXXXXXRMAIQDAKKHPWV-----CWDFNHNDYMSDQEKSLKLIEQSN-------FHRS 456
R+ +Q+ +HPW+ + N D + + + L+ +
Sbjct: 305 LDANPYSRLTVQEVLEHPWIRNAERAPNVNLGDNVRTKIQQFLLMNRFKKKVLRIVADNL 364
Query: 457 PSEQVEQICISEHEVDTAVGG-------------IGHKIKNAVGKFLPSTKSNDESNTNS 503
P+E++ I +DT G IG + + K L D + S
Sbjct: 365 PNEEIAAIVQMFQTMDTDKNGHLTFEELRDGLKKIGQVVPDGDVKMLMDAADTDGNGMLS 424
Query: 504 VNEFNDSGNNKYIDGC---LNSCASYTD---NGNLILSEETYISPKDSTGYGNEGTNLVE 557
+EF + GC L Y D NG + L E D G+ N ++
Sbjct: 425 CDEFVTLSIHLKRMGCDEHLQEAFKYFDKNGNGFIELDELKVALCDDKLGHANGNDQWIK 484
Query: 558 D 558
D
Sbjct: 485 D 485
>At1g54610 [D] KOG0600 Cdc2-related protein kinase
Length = 572
Score = 86.7 bits (213), Expect = 2e-16
Identities = 53/174 (30%), Positives = 94/174 (53%), Gaps = 29/174 (16%)
Query: 113 NTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIEDE 172
+T+E I+++G G + V A+D++T ++VA+K V +F N +E E
Sbjct: 116 DTFEKIDKIGQGTYSNVYKAKDMLTGKIVALKKV----------RFDN--------LEPE 157
Query: 173 KIK---REIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKAR 229
+K REI ++++ H +VVKL ++ S +YLV +Y V++
Sbjct: 158 SVKFMAREILVLRRLDHPNVVKLEGLVTSRMSCSLYLVFQYMDHDLAGLASSPVVK---- 213
Query: 230 GPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGV 283
S + + R ++ GLE+ H +G++HRDIK +NLL+ + G++KI+DFG+
Sbjct: 214 ----FSESEVKCLMRQLISGLEHCHSRGVLHRDIKGSNLLIDDGGVLKIADFGL 263
>At1g10940 [T] KOG0583 Serine/threonine protein kinase
Length = 363
Score = 86.7 bits (213), Expect = 2e-16
Identities = 78/318 (24%), Positives = 131/318 (40%), Gaps = 61/318 (19%)
Query: 112 LNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIED 171
++ YE+++++G G G +L + +K+LVA+K + R K D
Sbjct: 1 MDKYELVKDIGAGNFGVARLMKVKNSKELVAMKYIERGPK------------------ID 42
Query: 172 EKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKARGP 231
E + REI + H ++++ EV+ + + +EY + GE+ + I + R
Sbjct: 43 ENVAREIINHRSLRHPNIIRFKEVV--LTPTHLAIAMEYAAGGEL----FERICSAGR-- 94
Query: 232 PLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLL--SEDGIVKISDFGVXXXXXX 289
S R F+ ++ G+ Y H I HRD+K N LL S +KI DFG
Sbjct: 95 --FSEDEARYFFQQLISGVSYCHAMQICHRDLKLENTLLDGSPAPRLKICDFG------- 145
Query: 290 XXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGITL 349
T GTPA+ APE+ S+ D+W+ G+TL
Sbjct: 146 -YSKSSLLHSRPKSTVGTPAYIAPEVL--------------SRREYDGKMADVWSCGVTL 190
Query: 350 HCLLFGMLPFISDYELELFDKIVNEPLVFEPYQKIEQCQVSQVECKEEYEEAQXXXXXXX 409
+ +L G PF + + F K + + + + Y+ + +SQ +CK
Sbjct: 191 YVMLVGAYPFEDQEDPKNFRKTIQKIMAVQ-YKIPDYVHISQ-DCKN-------LLSRIF 241
Query: 410 XXXXXXRMAIQDAKKHPW 427
R+ I + KKH W
Sbjct: 242 VANSLKRITIAEIKKHSW 259
>CE28674 [T] KOG0201 Serine/threonine protein kinase
Length = 651
Score = 86.3 bits (212), Expect = 2e-16
Identities = 72/257 (28%), Positives = 109/257 (42%), Gaps = 49/257 (19%)
Query: 119 EELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIEDEKIKREI 178
E +G G G+V D T ++VAIKI++ Q+ E E I++EI
Sbjct: 36 ERIGRGSFGEVYKGIDNRTGRVVAIKIIDLE----------------QAEDEIEDIQQEI 79
Query: 179 AIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKARGPPLLSFQR 238
++ +C ++V K K K+++++EY G ++ G L
Sbjct: 80 QVLSQCDSQYVTKYFGSF--LKGSKLWIIMEYLGGGS-------ALDLTKSGK--LDESH 128
Query: 239 TREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXXXXXXXXXXXXXXX 298
I R +L GLEYLH + IHRDIK AN+L+SE G VK++DFGV
Sbjct: 129 IAVILREILKGLEYLHSERKIHRDIKAANVLVSEHGDVKVADFGVAGQLTETVKKRITF- 187
Query: 299 XXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGITLHCLLFGMLP 358
G+P + APE+ K+ + DIW++GIT L G P
Sbjct: 188 ------VGSPFWMAPELI---------------KQSSYDYKADIWSLGITAIELANGEPP 226
Query: 359 FISDYELELFDKIVNEP 375
+ + + I P
Sbjct: 227 HSDLHPMRVLFLIPKNP 243
>CE07510 [T] KOG0201 Serine/threonine protein kinase
Length = 653
Score = 86.3 bits (212), Expect = 2e-16
Identities = 72/257 (28%), Positives = 109/257 (42%), Gaps = 49/257 (19%)
Query: 119 EELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIEDEKIKREI 178
E +G G G+V D T ++VAIKI++ Q+ E E I++EI
Sbjct: 38 ERIGRGSFGEVYKGIDNRTGRVVAIKIIDLE----------------QAEDEIEDIQQEI 81
Query: 179 AIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKARGPPLLSFQR 238
++ +C ++V K K K+++++EY G ++ G L
Sbjct: 82 QVLSQCDSQYVTKYFGSF--LKGSKLWIIMEYLGGGS-------ALDLTKSGK--LDESH 130
Query: 239 TREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXXXXXXXXXXXXXXX 298
I R +L GLEYLH + IHRDIK AN+L+SE G VK++DFGV
Sbjct: 131 IAVILREILKGLEYLHSERKIHRDIKAANVLVSEHGDVKVADFGVAGQLTETVKKRITF- 189
Query: 299 XXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGITLHCLLFGMLP 358
G+P + APE+ K+ + DIW++GIT L G P
Sbjct: 190 ------VGSPFWMAPELI---------------KQSSYDYKADIWSLGITAIELANGEPP 228
Query: 359 FISDYELELFDKIVNEP 375
+ + + I P
Sbjct: 229 HSDLHPMRVLFLIPKNP 245
>At4g04720 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 531
Score = 86.3 bits (212), Expect = 2e-16
Identities = 82/323 (25%), Positives = 135/323 (41%), Gaps = 73/323 (22%)
Query: 115 YEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIEDEKI 174
Y + +ELG GQ G + +++ T A K + + K + DK E +
Sbjct: 80 YSLGKELGRGQFGITYMCKEIGTGNTYACKSILKRKLISKQDK--------------EDV 125
Query: 175 KREIAIMKKCHHE-HVVKLIEVLDDAKSRKIYLVLEYCSKGEIK---WCPGDVIETKARG 230
KREI IM+ + ++V++ +D +S I+LV+E C+ GE+ G E A G
Sbjct: 126 KREIQIMQYLSGQPNIVEIKGAYEDRQS--IHLVMELCAGGELFDRIIAQGHYSERAAAG 183
Query: 231 PPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLS---EDGIVKISDFGVXXXX 287
I R ++ ++ HF G++HRD+KP N LLS E+ ++K +DFG+
Sbjct: 184 -----------IIRSIVNVVQICHFMGVVHRDLKPENFLLSSKEENAMLKATDFGL---- 228
Query: 288 XXXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGI 347
G+ + APE+ KE DIW+ G+
Sbjct: 229 ----SVFIEEGKVYRDIVGSAYYVAPEVL----------RRSYGKE------IDIWSAGV 268
Query: 348 TLHCLLFGMLPFISDYELELFDKIVNEPLVF--EPYQKIEQCQVSQVECKEEYEEAQXXX 405
L+ LL G+ PF ++ E +FD+++ + F EP+ I E A+
Sbjct: 269 ILYILLSGVPPFWAENEKGIFDEVIKGEIDFVSEPWPSIS-------------ESAKDLV 315
Query: 406 XXXXXXXXXXRMAIQDAKKHPWV 428
R+ +HPW+
Sbjct: 316 RKMLTKDPKRRITAAQVLEHPWI 338
>7293666 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 576
Score = 86.3 bits (212), Expect = 2e-16
Identities = 76/266 (28%), Positives = 115/266 (42%), Gaps = 49/266 (18%)
Query: 106 ISKRKVLNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTP 165
I++RK TY+ + G G K D+ T + A KIV++ N K
Sbjct: 19 INQRK---TYKRMRFFGKGGFAKCYEIIDVETDDVFAGKIVSKKLMIKHNQK-------- 67
Query: 166 QSGIEDEKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIE 225
EK +EI I + +H ++VK +D S+ IY+VLE C K + +E
Sbjct: 68 ------EKTAQEITIHRSLNHPNIVKFHNYFED--SQNIYIVLELCKKRSM-------ME 112
Query: 226 TKARGPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXX 285
R + F+ I++ ++ G++YLH IIHRD+K NL L++ VKI DFG+
Sbjct: 113 LHKRRKSITEFECRYYIYQ-IIQGVKYLHDNRIIHRDLKLGNLFLNDLLHVKIGDFGLAT 171
Query: 286 XXXXXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAM 345
GTP + APEI + SF DIW++
Sbjct: 172 RIEYEGERKKT-------LCGTPNYIAPEILTKKGH---------------SFEVDIWSI 209
Query: 346 GITLHCLLFGMLPFISDYELELFDKI 371
G ++ LL G PF + + + KI
Sbjct: 210 GCVMYTLLVGQPPFETKTLKDTYSKI 235
>7293249 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1390
Score = 86.3 bits (212), Expect = 2e-16
Identities = 87/352 (24%), Positives = 148/352 (41%), Gaps = 63/352 (17%)
Query: 93 VKETNTVSLEYDPISK-----RKVLNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVN 147
+K + +Y P++ R + + I+ +G G G+V+L R + Q+ A+K ++
Sbjct: 60 LKNIEQYAAKYKPLAMQINQLRMNVEDFHFIKLIGAGAFGEVQLVRHKSSSQVYAMKRLS 119
Query: 148 RHKKRTFNDKFSNRFKTPQSGIEDEKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLV 207
+ + K P S E E IM + E +V+L DAK +Y+V
Sbjct: 120 KFEM----------MKRPDSAFFWE----ERHIMAHANSEWIVQLHFAFQDAKY--LYMV 163
Query: 208 LEYCSKGEIKWCPGDVIETKARGPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPAN 267
+++ G+I GD P + T E V+L L+ +H G +HRD+KP N
Sbjct: 164 MDFMPGGDIVSLMGDYDI-----PEKWAIFYTME----VVLALDTIHNMGFVHRDVKPDN 214
Query: 268 LLLSEDGIVKISDFGVXXXXXXXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDL 327
+LL G +K++DFG + GTP + +PE+ + ++
Sbjct: 215 MLLDSYGHLKLADFG------TCMRMGANGQVVSSNAVGTPDYISPEVLQSQGVDNEYGR 268
Query: 328 DPNSKEPIISFPTDIWAMGITLHCLLFGMLPFISDYELELFDKIVN--EPLVFEPYQKIE 385
+ D W++GI L+ +LFG PF +D + + KI++ L F P
Sbjct: 269 E-----------CDWWSVGIFLYEMLFGETPFYADSLVGTYGKIMDHKNSLSFPP----- 312
Query: 386 QCQVSQVECKEEYEEAQXXXXXXXXXXXXXRMAIQDAKKHPWV---CWDFNH 434
+VE E+ +A R I+D K HP+ W F++
Sbjct: 313 -----EVEISEQ-AKALIRAFLTDRTQRLGRYGIEDIKAHPFFRNDTWSFDN 358
>SPBC106.10 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 512
Score = 85.9 bits (211), Expect = 3e-16
Identities = 87/327 (26%), Positives = 132/327 (39%), Gaps = 61/327 (18%)
Query: 58 EKQRQRQLNHPLHQNHIRTVLGSHLNSGQRITYGPVKETNTVSLEYDPISKRKVLNTYEI 117
E +R L HIR V S L QR P T R + +
Sbjct: 153 EHGERRSAMDGLRDRHIRKVRVSQLLDLQRRRIRPADHTT---------KDRYGIQDFNF 203
Query: 118 IEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIEDEKIKRE 177
++ LG G G+V L + + AIK++ KK+ + K + E E
Sbjct: 204 LQTLGTGSFGRVHLVQSNHNRLYYAIKVLE--KKKIVDMK------------QIEHTCDE 249
Query: 178 IAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKARGPPLLSFQ 237
I+ + H + L DAK+ +++V+++ GE+ ++ R P ++
Sbjct: 250 RYILSRVQHPFITILWGTFQDAKN--LFMVMDFAEGGELF----SLLRKCHRFPEKVAKF 303
Query: 238 RTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXXXXXXXXXXXXXX 297
E V+L L+YLH I++RD+KP NLLL G +KI DFG
Sbjct: 304 YAAE----VILALDYLHHNQIVYRDLKPENLLLDRFGHLKIVDFG---------FAKRVS 350
Query: 298 XXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGITLHCLLFGML 357
GTP + APEI L P +K D W++GI + +L G
Sbjct: 351 TSNCCTLCGTPDYLAPEI---------ISLKPYNK------AADWWSLGILIFEMLAGYP 395
Query: 358 PFISDYELELFDKI----VNEPLVFEP 380
PF S+ ++L++ I VN P F P
Sbjct: 396 PFYSENPMKLYENILEGKVNYPSYFSP 422
>SPAC1F3.02c [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 1116
Score = 85.9 bits (211), Expect = 3e-16
Identities = 73/256 (28%), Positives = 114/256 (44%), Gaps = 35/256 (13%)
Query: 119 EELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIEDEKIKREI 178
E +G+G +GKV LA ++ T +L+A+K V + R + I D I EI
Sbjct: 829 ELIGNGTYGKVFLAMNINTGELIAVKQVE------IPQTINGRHDQLRKDIVDS-INAEI 881
Query: 179 AIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKARGPPLLSFQR 238
+++ H ++V+ + + I + LEY S G I C + GP Q
Sbjct: 882 SMIADLDHLNIVQYLGF--EKTETDISIFLEYVSGGSIGRC------LRNYGP--FEEQL 931
Query: 239 TREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXXXXXXXXXXXXXXX 298
R + R VL GL YLH +GIIHRD+K NLL+ DG+ KISDFG+
Sbjct: 932 VRFVSRQVLYGLSYLHSKGIIHRDLKADNLLIDFDGVCKISDFGI-----SKHSDNVYDN 986
Query: 299 XXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGITLHCLLFGMLP 358
G+ + APE+ ++ S D+W++G + +L G P
Sbjct: 987 DANLSMQGSIFWMAPEVI-------------HNDHQGYSAKVDVWSLGCVVLEMLAGRRP 1033
Query: 359 FISDYELELFDKIVNE 374
+ +D ++ K+ E
Sbjct: 1034 WSTDEAIQAMFKLGTE 1049
>Hs15011880 [T] KOG0201 Serine/threonine protein kinase
Length = 416
Score = 85.9 bits (211), Expect = 3e-16
Identities = 68/231 (29%), Positives = 103/231 (44%), Gaps = 49/231 (21%)
Query: 118 IEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIEDEKIKRE 177
+E +G G G+V D T+Q+VAIKI++ + E E I++E
Sbjct: 27 LERIGKGSFGEVFKGIDNRTQQVVAIKIIDLEEAED----------------EIEDIQQE 70
Query: 178 IAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKARGPPLLSFQ 237
I ++ +C +V K K K+++++EY G D++ R P FQ
Sbjct: 71 ITVLSQCDSSYVTKYYGSY--LKGSKLWIIMEYLGGGSAL----DLL----RAGPFDEFQ 120
Query: 238 RTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXXXXXXXXXXXXXX 297
+ + +L GL+YLH + IHRDIK AN+LLSE G VK++DFGV
Sbjct: 121 -IATMLKEILKGLDYLHSEKKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTF 179
Query: 298 XXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGIT 348
GTP + APE+ ++ DIW++GIT
Sbjct: 180 -------VGTPFWMAPEVI---------------QQSAYDSKADIWSLGIT 208
>At2g23030 [T] KOG0583 Serine/threonine protein kinase
Length = 339
Score = 85.9 bits (211), Expect = 3e-16
Identities = 73/265 (27%), Positives = 115/265 (42%), Gaps = 52/265 (19%)
Query: 112 LNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIED 171
+ YE++++LG G G +L R+ T +LVA+K ++R K D
Sbjct: 1 MEKYEMVKDLGFGNFGLARLMRNKQTNELVAVKFIDRGYK------------------ID 42
Query: 172 EKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKARGP 231
E + REI + +H ++V+ EV+ + +V+EY + GE+ + I + R
Sbjct: 43 ENVAREIINHRALNHPNIVRFKEVV--LTPTHLGIVMEYAAGGEL----FERISSVGR-- 94
Query: 232 PLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLL--SEDGIVKISDFGVXXXXXX 289
S R F+ ++ G+ YLH I HRD+K N LL S +KI DFG
Sbjct: 95 --FSEAEARYFFQQLICGVHYLHALQICHRDLKLENTLLDGSPAPRLKICDFG------- 145
Query: 290 XXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGITL 349
T GTPA+ APE+ + + D S D+W+ G+ L
Sbjct: 146 -YSKSSVLHSNPKSTVGTPAYIAPEV------FCRSEYDGKS--------VDVWSCGVAL 190
Query: 350 HCLLFGMLPFISDYELELFDKIVNE 374
+ +L G PF + F K V +
Sbjct: 191 YVMLVGAYPFEDPKDPRNFRKTVQK 215
>7297542 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 353
Score = 85.9 bits (211), Expect = 3e-16
Identities = 69/267 (25%), Positives = 114/267 (41%), Gaps = 49/267 (18%)
Query: 112 LNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIED 171
L+ +E I+ LG G G+V + + TK A+KI+++ K +
Sbjct: 43 LDDFERIKTLGTGSFGRVMIVQHKPTKDYYAMKILDKQKVVKLK--------------QV 88
Query: 172 EKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKARGP 231
E E I++ +V L D + +Y+VLEY PG + + R
Sbjct: 89 EHTLNEKRILQAIQFPFLVSLRYHFKD--NSNLYMVLEYV--------PGGEMFSHLRKV 138
Query: 232 PLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXXXXXXXX 291
S +R ++L EYLH+ +I+RD+KP NLL+ G +K++DFG
Sbjct: 139 GRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYLKVTDFGFAKRVKGRT 198
Query: 292 XXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGITLHC 351
GTP + APEI L + K D WA+G+ ++
Sbjct: 199 WT----------LCGTPEYLAPEIILSKGYNK---------------AVDWWALGVLVYE 233
Query: 352 LLFGMLPFISDYELELFDKIVNEPLVF 378
+ G PF +D +++++KIV+ + F
Sbjct: 234 MAAGYPPFFADQPIQIYEKIVSGKVRF 260
>7296166 [T] KOG0614 cGMP-dependent protein kinase
Length = 768
Score = 85.9 bits (211), Expect = 3e-16
Identities = 86/325 (26%), Positives = 126/325 (38%), Gaps = 60/325 (18%)
Query: 112 LNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIED 171
L E++ LG G G+V+L + ++ + K+ + K ++
Sbjct: 454 LTDLEVVSTLGIGGFGRVELVKAHHQDRVDIFALKCLKKRHIVDTK------------QE 501
Query: 172 EKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKARGP 231
E I E IM + +L D K +Y++LE C GEI W T R
Sbjct: 502 EHIFSERHIMLSSRSPFICRLYRTFRDEKY--VYMLLEACMGGEI-W-------TMLRDR 551
Query: 232 PLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXXXXXXXX 291
+ I VL EYLH +GII+RD+KP NL+L E G VKI DFG
Sbjct: 552 GSFEDNAAQFIIGCVLQAFEYLHARGIIYRDLKPENLMLDERGYVKIVDFGFAKQIGTSS 611
Query: 292 XXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGITLHC 351
GTP + APEI L + + D WA+GI +H
Sbjct: 612 KTWTF--------CGTPEYVAPEIILNKGHDR---------------AVDYWALGILIHE 648
Query: 352 LLFGMLPFISDYELELFDKIVN--EPLVFEPYQKIEQCQVSQVECKEEYEEAQXXXXXXX 409
LL G PF + ++ ++ I+ + + F + Q+ + C++ E
Sbjct: 649 LLNGTPPFSAPDPMQTYNLILKGIDMIAFPKHISRWAVQLIKRLCRDVPSERLGYQTG-- 706
Query: 410 XXXXXXRMAIQDAKKHPWVC---WD 431
IQD KKH W WD
Sbjct: 707 --------GIQDIKKHKWFLGFDWD 723
>HsM4507279 [D] KOG0580 Serine/threonine protein kinase
Length = 402
Score = 85.5 bits (210), Expect = 4e-16
Identities = 75/335 (22%), Positives = 135/335 (39%), Gaps = 63/335 (18%)
Query: 112 LNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIED 171
L +EI LG G+ G V LAR+ +K ++A+K++ + + ++G+E
Sbjct: 129 LEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLE-------------KAGVEH 175
Query: 172 EKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKARGP 231
+ ++RE+ I H ++++L DA ++YL+LEY G + + +
Sbjct: 176 Q-LRREVEIQSHLRHPNILRLYGYFHDAT--RVYLILEYAPLG--------TVYRELQKL 224
Query: 232 PLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXXXXXXXX 291
QRT ++ + L Y H + +IHRDIKP NLLL G +KI+DFG
Sbjct: 225 SKFDEQRTANLYNRIANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFG--------- 275
Query: 292 XXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGITLHC 351
GT + PE ++E + D+W++G+ +
Sbjct: 276 WSVHAPSSRRTTLCGTLDYLPPE--MIEGRMH-------------DEKVDLWSLGVLCYE 320
Query: 352 LLFGMLPFISDYELELFDKIVNEPLVFEPYQKIEQCQVSQVECKEEYEEAQXXXXXXXXX 411
L G PF ++ E + +I F + E A+
Sbjct: 321 FLVGKPPFEANTYQETYKRISRVEFTFPDFVT---------------EGARDLISRLLKH 365
Query: 412 XXXXRMAIQDAKKHPWVCWDFNHNDYMSDQEKSLK 446
R +++ +HPW+ + + ++E + K
Sbjct: 366 NPSQRPMLREVLEHPWITANSSKPSNCQNKESASK 400
>CE27573 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 1420
Score = 85.5 bits (210), Expect = 4e-16
Identities = 64/249 (25%), Positives = 110/249 (43%), Gaps = 47/249 (18%)
Query: 115 YEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIEDEKI 174
+ +++ + G G V A D+ + +++A K++ ++ + I
Sbjct: 1125 WALLDHIASGSFGSVHRAMDIDSHRVIAAKVMRIQREN------------------HKAI 1166
Query: 175 KREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEI-KWCPGDVIETKARGPPL 233
+ EI I ++ HE++VK V + + + +EYCS+G + + C G
Sbjct: 1167 ESEINIFRQLIHENLVKYYGV--QVEDSDVIIFMEYCSQGTLERICHGK----------- 1213
Query: 234 LSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXXXXXXXXXX 293
+ + R+ +L ++YLH IIHRDIKPAN+ L + ++K+ DFG
Sbjct: 1214 MDLKMVRQYTNSLLRAVQYLHSHKIIHRDIKPANIFLDKCTVLKLGDFGCSSRLVESSTV 1273
Query: 294 XXXXXXXXAKTAGTPAFFAPEICLV---EDTIKKFDLDPNSKEPIISFPTDIWAMGITLH 350
TAGTP F APEI ++T + S DIWA+G T+
Sbjct: 1274 YGEFQT----TAGTPQFMAPEIYSYGEKDETTGSYSGYGRS--------VDIWALGATVV 1321
Query: 351 CLLFGMLPF 359
++ G +PF
Sbjct: 1322 NMMTGKVPF 1330
>CE07737 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 1418
Score = 85.5 bits (210), Expect = 4e-16
Identities = 64/249 (25%), Positives = 110/249 (43%), Gaps = 47/249 (18%)
Query: 115 YEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIEDEKI 174
+ +++ + G G V A D+ + +++A K++ ++ + I
Sbjct: 1125 WALLDHIASGSFGSVHRAMDIDSHRVIAAKVMRIQREN------------------HKAI 1166
Query: 175 KREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEI-KWCPGDVIETKARGPPL 233
+ EI I ++ HE++VK V + + + +EYCS+G + + C G
Sbjct: 1167 ESEINIFRQLIHENLVKYYGV--QVEDSDVIIFMEYCSQGTLERICHGK----------- 1213
Query: 234 LSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXXXXXXXXXX 293
+ + R+ +L ++YLH IIHRDIKPAN+ L + ++K+ DFG
Sbjct: 1214 MDLKMVRQYTNSLLRAVQYLHSHKIIHRDIKPANIFLDKCTVLKLGDFGCSSRLVESSTV 1273
Query: 294 XXXXXXXXAKTAGTPAFFAPEICLV---EDTIKKFDLDPNSKEPIISFPTDIWAMGITLH 350
TAGTP F APEI ++T + S DIWA+G T+
Sbjct: 1274 YGEFQT----TAGTPQFMAPEIYSYGEKDETTGSYSGYGRS--------VDIWALGATVV 1321
Query: 351 CLLFGMLPF 359
++ G +PF
Sbjct: 1322 NMMTGKVPF 1330
>Hs20127418 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 664
Score = 85.1 bits (209), Expect = 5e-16
Identities = 83/344 (24%), Positives = 137/344 (39%), Gaps = 62/344 (18%)
Query: 115 YEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIEDEKI 174
Y++ E++G G V+ L T A KI+N K S + +K+
Sbjct: 14 YQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKL---------------SARDHQKL 58
Query: 175 KREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKARGPPLL 234
+RE I + H ++V+L + + + YLV + + GE+ D++ +
Sbjct: 59 EREARICRLLKHSNIVRLHDSISEEGFH--YLVFDLVTGGELF---EDIVARE-----YY 108
Query: 235 SFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLS---EDGIVKISDFGVXXXXXXXX 291
S + +L + + H G++HRD+KP NLLL+ + VK++DFG+
Sbjct: 109 SEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQ 168
Query: 292 XXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGITLHC 351
AGTP + +PE+ E K P DIWA G+ L+
Sbjct: 169 QAWFGF-------AGTPGYLSPEVLRKEAYGK---------------PVDIWACGVILYI 206
Query: 352 LLFGMLPFISDYELELFDKIVNEPLVFEPYQKIEQCQVSQVECKEEYEEAQXXXXXXXXX 411
LL G PF + + +L+ +I K E EA+
Sbjct: 207 LLVGYPPFWDEDQHKLYQQI-----------KAGAYDFPSPEWDTVTPEAKNLINQMLTI 255
Query: 412 XXXXRMAIQDAKKHPWVCWDFNHNDYMSDQEKSLKLIEQSNFHR 455
R+ +A KHPWVC M QE +++ +++ N R
Sbjct: 256 NPAKRITAHEALKHPWVCQRSTVASMMHRQE-TVECLKKFNARR 298
>At1g09000 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 666
Score = 85.1 bits (209), Expect = 5e-16
Identities = 75/276 (27%), Positives = 127/276 (45%), Gaps = 47/276 (17%)
Query: 89 TYGPVKETNTVSLEYDPISKRKVLNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNR 148
++ P NTV + PIS RK + +G G G V + +L + +L+A+K V
Sbjct: 51 SFSPPPPANTVDMA-PPISWRKG-------QLIGRGAFGTVYMGMNLDSGELLAVKQV-- 100
Query: 149 HKKRTFNDKFSNRFKTPQSGIEDEKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVL 208
F+++ KT Q+ I++ ++ E+ ++K H ++V+ + + + + I +L
Sbjct: 101 ----LIAANFASKEKT-QAHIQE--LEEEVKLLKNLSHPNIVRYLGTVREDDTLNI--LL 151
Query: 209 EYCSKGEIKWCPGDVIETKARGPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANL 268
E+ G I ++E P + TR++ LLGLEYLH I+HRDIK AN+
Sbjct: 152 EFVPGGSIS----SLLEKFGPFPESVVRTYTRQL----LLGLEYLHNHAIMHRDIKGANI 203
Query: 269 LLSEDGIVKISDFGVXXXXXXXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLD 328
L+ G +K++DFG GTP + APE+ L
Sbjct: 204 LVDNKGCIKLADFG-----ASKQVAELATMTGAKSMKGTPYWMAPEVIL----------- 247
Query: 329 PNSKEPIISFPTDIWAMGITLHCLLFGMLPFISDYE 364
+ SF DIW++G T+ ++ G P+ Y+
Sbjct: 248 ----QTGHSFSADIWSVGCTVIEMVTGKAPWSQQYK 279
>7297009 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 392
Score = 85.1 bits (209), Expect = 5e-16
Identities = 59/172 (34%), Positives = 83/172 (47%), Gaps = 27/172 (15%)
Query: 112 LNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIED 171
++ YE + LG G +G V RD T LVA+K RF +
Sbjct: 1 MDRYEKLSRLGEGSYGVVYKCRDRETGALVAVK----------------RFVESEDDPAI 44
Query: 172 EKIK-REIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKARG 230
KI REI ++K H ++V L+EV + R+++LV E+C V+ R
Sbjct: 45 RKIALREIRLLKNLKHPNLVSLLEVF--RRKRRLHLVFEFCEL--------TVLHELERH 94
Query: 231 PPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFG 282
P T++I LLG+ Y H QG +HRDIKP N+LL+ G VK+ DFG
Sbjct: 95 PQGCPEHLTKQICYQTLLGVAYCHKQGCLHRDIKPENILLTAQGQVKLCDFG 146
>Hs7661946 [T] KOG4250 TANK binding protein kinase TBK1
Length = 716
Score = 84.7 bits (208), Expect = 7e-16
Identities = 71/246 (28%), Positives = 114/246 (45%), Gaps = 44/246 (17%)
Query: 121 LGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIEDEKIKREIAI 180
LG G V AR+ + +LVA+K+ N + + P+ E RE +
Sbjct: 15 LGQGATASVYKARNKKSGELVAVKVFN-----------TTSYLRPR-----EVQVREFEV 58
Query: 181 MKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIET--KARGPPLLSFQR 238
++K +H+++VKL V + SR+ LV+EYCS G + V+E+ A G P F
Sbjct: 59 LRKLNHQNIVKLFAVEETGGSRQKVLVMEYCSSGSLL----SVLESPENAFGLPEDEF-- 112
Query: 239 TREIFRGVLLGLEYLHFQGIIHRDIKPANL--LLSEDG--IVKISDFGVXXXXXXXXXXX 294
+ R V+ G+ +L GI+HRDIKP N+ L+ E+G I K++DFG
Sbjct: 113 -LVVLRCVVAGMNHLRENGIVHRDIKPGNIMRLVGEEGQSIYKLTDFG--------AARE 163
Query: 295 XXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGITLHCLLF 354
GT + P+ + E + + ++ D+W++G+TL+
Sbjct: 164 LDDDEKFVSVYGTEEYLHPD--MYERAVLR-----KPQQKAFGVTVDLWSIGVTLYHAAT 216
Query: 355 GMLPFI 360
G LPFI
Sbjct: 217 GSLPFI 222
>Hs7019543 [T] KOG0582 Ste20-like serine/threonine protein kinase
Length = 547
Score = 84.7 bits (208), Expect = 7e-16
Identities = 72/249 (28%), Positives = 109/249 (42%), Gaps = 38/249 (15%)
Query: 113 NTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIEDE 172
+ YE+ E +G G V+ A ++ VAIK +N K +T D+
Sbjct: 63 DAYELQEVIGSGATAVVQAALCKPRQERVAIKRINLEKCQTSMDE--------------- 107
Query: 173 KIKREIAIMKKCHHEHVVKLIE--VLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKARG 230
+ +EI M +C H +VV V+ D +++LV++ S G + ++
Sbjct: 108 -LLKEIQAMSQCSHPNVVTYYTSFVVKD----ELWLVMKLLSGGSMLDIIKYIVNRGEHK 162
Query: 231 PPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXXXXXXX 290
+L I + VL GL+YLH G IHRD+K N+LL EDG V+I+DFGV
Sbjct: 163 NGVLEEAIIATILKEVLEGLDYLHRNGQIHRDLKAGNILLGEDGSVQIADFGVSAFLATG 222
Query: 291 XXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGITLH 350
GTP + APE V + ++ +D F D+W+ GIT
Sbjct: 223 GDVTRNKVRKT--FVGTPCWMAPE---VMEQVRGYD-----------FKADMWSFGITAI 266
Query: 351 CLLFGMLPF 359
L G P+
Sbjct: 267 ELATGAAPY 275
>CE26212 [T] KOG0582 Ste20-like serine/threonine protein kinase
Length = 545
Score = 84.7 bits (208), Expect = 7e-16
Identities = 72/254 (28%), Positives = 110/254 (42%), Gaps = 44/254 (17%)
Query: 113 NTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIEDE 172
+ Y++ E +G G V A L + VAIK +N K +T D+ S+
Sbjct: 55 SAYKLDESIGVGATATVFTAYCLPRNEKVAIKCINLEKCQTSVDELSH------------ 102
Query: 173 KIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKAR--G 230
EI M +C+H +VV ++++V+ + G + D+++ K + G
Sbjct: 103 ----EIQAMSQCNHPNVVSYYTSF--IAQEELWVVMRLLNCGSML----DILKRKVKAIG 152
Query: 231 PPLLSFQRTREI-----FRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXX 285
F E+ R VL GLEY H G IHRDIK N+LL++DG ++I+DFGV
Sbjct: 153 KEQAQFGVLDEVSIATVLREVLKGLEYFHLNGQIHRDIKAGNILLADDGTIQIADFGVSG 212
Query: 286 XXXXXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAM 345
GTP + APE V + ++ +D F DIW++
Sbjct: 213 WLASSGGDLSRQKVRHT-FVGTPCWMAPE---VMEQVQGYD-----------FKADIWSL 257
Query: 346 GITLHCLLFGMLPF 359
GI L G P+
Sbjct: 258 GILAIELATGTAPY 271
>At3g49370 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 594
Score = 84.7 bits (208), Expect = 7e-16
Identities = 66/261 (25%), Positives = 109/261 (41%), Gaps = 54/261 (20%)
Query: 115 YEIIEELGHGQHGKV---KLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIED 171
YE+ E+G G G K + + Q VA+KI+++ K S +
Sbjct: 142 YELGREVGRGHFGHTCWAKAKKGKIKGQTVAVKIISKSKMT--------------SALSI 187
Query: 172 EKIKREIAIMKKCH-HEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKARG 230
E ++RE+ ++K H H+VK +V +D S +++V+E C GE+ ++ R
Sbjct: 188 EDVRREVKLLKALSGHSHMVKFYDVFED--SDNVFVVMELCEGGELL---DSILARGGRY 242
Query: 231 PPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLL---SEDGIVKISDFGVXXXX 287
P + I +L + H QG++HRD+KP N L +ED ++K+ DFG+
Sbjct: 243 PEA----EAKRILVQILSATAFFHLQGVVHRDLKPENFLFTSKNEDAVLKVIDFGLSDYA 298
Query: 288 XXXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGI 347
G+ + APE+ S DIW++G+
Sbjct: 299 RFDQRLN--------DVVGSAYYVAPEVL----------------HRSYSTEADIWSIGV 334
Query: 348 TLHCLLFGMLPFISDYELELF 368
+ LL G PF E +F
Sbjct: 335 ISYILLCGSRPFYGRTESAIF 355
>At1g50700 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 521
Score = 84.7 bits (208), Expect = 7e-16
Identities = 88/343 (25%), Positives = 143/343 (41%), Gaps = 69/343 (20%)
Query: 92 PVKETNTVSLEYDPISKRKVLNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKK 151
P K + ++ P K+ Y + +ELG GQ G L + T + A K +++ K
Sbjct: 52 PAKHSGAAAILEKPYEDVKLF--YTLSKELGRGQFGVTYLCTEKSTGKRFACKSISKKKL 109
Query: 152 RTFNDKFSNRFKTPQSGIEDEKIKREIAIMKKCHHE-HVVKLIEVLDDAKSRKIYLVLEY 210
T DK E ++REI IM+ + ++V+ +D K+ + LV+E
Sbjct: 110 VTKGDK--------------EDMRREIQIMQHLSGQPNIVEFKGAYEDEKA--VNLVMEL 153
Query: 211 CSKGEIKWCPGDVIETKARGPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLL 270
C+ GE+ D I K S + + R ++ + HF G++HRD+KP N LL
Sbjct: 154 CAGGELF----DRILAKGH----YSERAAASVCRQIVNVVNICHFMGVMHRDLKPENFLL 205
Query: 271 S---EDGIVKISDFGVXXXXXXXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDL 327
S E ++K +DFG+ G+ + APE+ +K+
Sbjct: 206 SSKDEKALIKATDFGL--------SVFIEEGRVYKDIVGSAYYVAPEV------LKR--- 248
Query: 328 DPNSKEPIISFPTDIWAMGITLHCLLFGMLPFISDYELELFDKIVNEPLVFE--PYQKIE 385
KE DIW+ GI L+ LL G+ PF ++ E +FD I+ + FE P+ I
Sbjct: 249 -RYGKE------IDIWSAGIILYILLSGVPPFWAETEKGIFDAILEGEIDFESQPWPSIS 301
Query: 386 QCQVSQVECKEEYEEAQXXXXXXXXXXXXXRMAIQDAKKHPWV 428
A+ R++ + KHPW+
Sbjct: 302 -------------NSAKDLVRRMLTQDPKRRISAAEVLKHPWL 331
>7300224 [T] KOG0201 Serine/threonine protein kinase
Length = 642
Score = 84.7 bits (208), Expect = 7e-16
Identities = 70/232 (30%), Positives = 104/232 (44%), Gaps = 53/232 (22%)
Query: 119 EELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIEDEKIKREI 178
E +G G G+V D T+Q+VAIKI++ + E + I++EI
Sbjct: 17 ERIGKGSFGEVFKGIDNRTQQVVAIKIIDLEEAED----------------EIDDIQQEI 60
Query: 179 AIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKARGPPLLSFQR 238
++ +C +V K K K+++++EY G ++ G SF+
Sbjct: 61 MVLSQCDSPYVTKYYGSF--LKGTKLWIIMEYLGGGS-------ALDLMKAG----SFEE 107
Query: 239 TRE--IFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXXXXXXXXXXXXX 296
I R VL GL+YLH + +HRDIK AN+LLSE G VK++DFGV
Sbjct: 108 MHIGIILREVLKGLDYLHSERKLHRDIKAANVLLSEQGDVKLADFGVAGQLTNTTSKRNT 167
Query: 297 XXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGIT 348
GTP + APE+ IK+ D + DIW++GIT
Sbjct: 168 F-------VGTPFWMAPEV------IKQSQYDAKA---------DIWSLGIT 197
>YOL113w [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 655
Score = 84.3 bits (207), Expect = 9e-16
Identities = 66/266 (24%), Positives = 121/266 (44%), Gaps = 36/266 (13%)
Query: 115 YEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIEDEKI 174
++++E+ G G G V L++ + Q + + H R ++ + + + + I
Sbjct: 360 FQLVEKAGQGASGAVYLSKRIKLPQENDPRFLKSHCHRVVGERVAIKQIRLSEQPKKQLI 419
Query: 175 KREIAIMKKCHHEHVVKLIE--VLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKARG-- 230
E+ +M E++V +E ++DD ++++++EY G C D+++ AR
Sbjct: 420 MNELLVMNDSRQENIVNFLEAYIIDD---EELWVIMEYMEGG----CLTDILDAVARSNT 472
Query: 231 ---PPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXXXX 287
L+ + I + GL++LH + IIHRDIK N+LL+ G+VKI+DFG
Sbjct: 473 GEHSSPLNENQMAYIVKETCQGLKFLHNKKIIHRDIKSDNILLNSQGLVKITDFG----- 527
Query: 288 XXXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGI 347
A GTP + APEI + +K D+W++GI
Sbjct: 528 --FCVELTEKRSKRATMVGTPYWMAPEIVNQKGYDEK---------------VDVWSLGI 570
Query: 348 TLHCLLFGMLPFISDYELELFDKIVN 373
L ++ G P++++ L+ I N
Sbjct: 571 MLIEMIEGEPPYLNEDPLKALYLIAN 596
>HsM8923212 [T] KOG4717 Serine/threonine protein kinase
Length = 244
Score = 84.3 bits (207), Expect = 9e-16
Identities = 69/265 (26%), Positives = 119/265 (44%), Gaps = 47/265 (17%)
Query: 110 KVLNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGI 169
K+ Y++ + LG G VKLAR + T + VA+K++++ K T +
Sbjct: 11 KIAGLYDLDKTLGRGHFAVVKLARHVFTGEKVAVKVIDKTKLDT---------------L 55
Query: 170 EDEKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKAR 229
+ +E+ MK H ++V+L EV+D K+YL+LE G++ D I
Sbjct: 56 ATGHLFQEVRCMKLVQHPNIVRLYEVID--TQTKLYLILELGDGGDM----FDYIMKHEE 109
Query: 230 GPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSE-DGIVKISDFGVXXXXX 288
G L+ ++ F ++ + Y H ++HRD+KP N++ E G+VK++DFG
Sbjct: 110 G---LNEDLAKKYFAQIVHAISYCHKLHVVHRDLKPENVVFFEKQGLVKLTDFGFSNKFQ 166
Query: 289 XXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGIT 348
+ G+ A+ APEI L ++ +D DIW++G+
Sbjct: 167 PGKKLTT--------SCGSLAYSAPEILLGDE----YDAP----------AVDIWSLGVI 204
Query: 349 LHCLLFGMLPFISDYELELFDKIVN 373
L L+ PF + E I++
Sbjct: 205 LFMLVCEQPPFQEANDSETLTMIMD 229
>CE07285 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 615
Score = 84.3 bits (207), Expect = 9e-16
Identities = 66/206 (32%), Positives = 91/206 (44%), Gaps = 33/206 (16%)
Query: 172 EKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKARGP 231
EK+ RE+ I ++ H ++V+ +D S+ +Y LE CSK + K RGP
Sbjct: 78 EKLTREVEIHRQLSHRNIVQFHHFFED--SQNVYFTLELCSKNSLMEL------NKQRGP 129
Query: 232 PLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXXXXXXXX 291
L+ R V G+++LH IIHRD+K NL L+E VKI DFG+
Sbjct: 130 --LTEHEARFYTIQVAEGVKHLHNLQIIHRDLKLGNLFLNEHLQVKIGDFGLATFCEKNE 187
Query: 292 XXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGITLHC 351
GTP + APE+ E +F DIWA+G L+
Sbjct: 188 KKMT--------RGGTPNYIAPEVL---------------NETGHAFEVDIWAIGCILYV 224
Query: 352 LLFGMLPFISDYELELFDKIVNEPLV 377
LLFG PF S E + +I N V
Sbjct: 225 LLFGSPPFESRRVQETYVRIKNNDYV 250
>At5g62310 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 1168
Score = 84.3 bits (207), Expect = 9e-16
Identities = 77/302 (25%), Positives = 125/302 (40%), Gaps = 51/302 (16%)
Query: 95 ETNTVSLEYDPISKRKVLNT----YEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHK 150
E SL P++ R T +EII+ + G G+V LA+ T L AIK++ +
Sbjct: 730 EDTVRSLRASPLNPRAKDRTSIEDFEIIKPISRGAFGRVFLAKKRATGDLFAIKVLKKAD 789
Query: 151 KRTFNDKFSNRFKTPQSGIEDEKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEY 210
N E I E I+ + VV+ ++ +YLV+EY
Sbjct: 790 MIRKNAV--------------ESILAERNILISVRNPFVVRFFYSFTCREN--LYLVMEY 833
Query: 211 CSKGEIKWCPGDVIETKARGPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLL 270
+ G++ + R L R V+L LEYLH IIHRD+KP NLL+
Sbjct: 834 LNGGDLF--------SLLRNLGCLDEDMARIYIAEVVLALEYLHSVNIIHRDLKPDNLLI 885
Query: 271 SEDGIVKISDFGVXXXXXXXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPN 330
++DG +K++DFG+ + G FFA + + + K D
Sbjct: 886 NQDGHIKLTDFGL----SKVGLINSTDDLSGESSLGNSGFFAEDGSKAQHSQGK---DSR 938
Query: 331 SKEPIISFP----------------TDIWAMGITLHCLLFGMLPFISDYELELFDKIVNE 374
K ++ P D W++G+ L +L G+ PF ++ ++F+ I+N
Sbjct: 939 KKHAVVGTPDYLAPEILLGMGHGKTADWWSVGVILFEVLVGIPPFNAETPQQIFENIINR 998
Query: 375 PL 376
+
Sbjct: 999 DI 1000
>SPAC23H4.02 [T] KOG0583 Serine/threonine protein kinase
Length = 532
Score = 84.0 bits (206), Expect = 1e-15
Identities = 66/263 (25%), Positives = 117/263 (44%), Gaps = 47/263 (17%)
Query: 97 NTVSLEYDPISKRKVLNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFND 156
++ S E + S + + + LG G KVKL + T + VA+K+V +ND
Sbjct: 5 SSASAESEKDSGNTYVGPWLLGRTLGQGNLAKVKLGKHFQTNEKVALKMV-------YND 57
Query: 157 KFSNRFKTPQSGIEDEKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEI 216
+ ++ ++++RE+ I+++ HH +++ L +V K L LEY
Sbjct: 58 ELEDKDTW-------KRLQREVTILRQLHHPNIITLYQVFRVPKYT--VLALEYMDTD-- 106
Query: 217 KWCPGDVIETKARGPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIV 276
+ + L TR+IFR ++ ++Y H + HRD+K N+LL++D +V
Sbjct: 107 -------LHSMVVKHNRLDECTTRKIFRQIVHAIDYCHLHRVAHRDLKLENILLNKDLVV 159
Query: 277 KISDFGVXXXXXXXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPII 336
K++DFG+ + + GTP + APE+ + +D
Sbjct: 160 KLTDFGL--------SNFMLDGSFLSTSCGTPHYAAPEVI----QGRYYD---------- 197
Query: 337 SFPTDIWAMGITLHCLLFGMLPF 359
D+W GI L+ +L G PF
Sbjct: 198 GCDVDVWGCGILLYLMLVGEFPF 220
>Hs5730055 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 685
Score = 84.0 bits (206), Expect = 1e-15
Identities = 66/239 (27%), Positives = 104/239 (42%), Gaps = 46/239 (19%)
Query: 121 LGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIEDEKIKREIAI 180
LG G K DL ++ A KI+ +R P + EKI +EI +
Sbjct: 88 LGKGGFAKCYEMTDLTNNKVYAAKIIPH-----------SRVAKPH---QREKIDKEIEL 133
Query: 181 MKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKARGPPLLSFQRTR 240
+ HH+HVV+ +D ++ IY++LEYCS+ + KAR +L+ R
Sbjct: 134 HRILHHKHVVQFYHYFEDKEN--IYILLEYCSRRSMAHI------LKAR--KVLTEPEVR 183
Query: 241 EIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXXXXXXXXXXXXXXXXX 300
R ++ GL+YLH Q I+HRD+K N ++E +K+ DFG+
Sbjct: 184 YYLRQIVSGLKYLHEQEILHRDLKLGNFFINEAMELKVGDFGLAARLEPLEHRRRT---- 239
Query: 301 XAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGITLHCLLFGMLPF 359
GTP + +PE+ + +DIWA+G ++ +L G PF
Sbjct: 240 ---ICGTPNYLSPEVLNKQGH---------------GCESDIWALGCVMYTMLLGRPPF 280
>Hs4506057 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 351
Score = 84.0 bits (206), Expect = 1e-15
Identities = 68/275 (24%), Positives = 115/275 (41%), Gaps = 49/275 (17%)
Query: 104 DPISKRKVLNTYEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFK 163
+P L +E + LG G G+V L + T+Q A+KI+++ K
Sbjct: 33 NPTQNNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLK-------- 84
Query: 164 TPQSGIEDEKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDV 223
+ E E I++ + +V+L D + +Y+V+EY PG
Sbjct: 85 ------QIEHTLNEKRILQAVNFPFLVRLEYAFKD--NSNLYMVMEYV--------PGGE 128
Query: 224 IETKARGPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGV 283
+ + R S R ++L EYLH +I+RD+KP NLL+ G ++++DFG
Sbjct: 129 MFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGF 188
Query: 284 XXXXXXXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIW 343
GTP + APEI L + K D W
Sbjct: 189 AKRVKGRTWT----------LCGTPEYLAPEIILSKGYNK---------------AVDWW 223
Query: 344 AMGITLHCLLFGMLPFISDYELELFDKIVNEPLVF 378
A+G+ ++ + G PF +D +++++KIV+ + F
Sbjct: 224 ALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRF 258
>Hs14042966 [T] KOG0583 Serine/threonine protein kinase
Length = 273
Score = 84.0 bits (206), Expect = 1e-15
Identities = 66/246 (26%), Positives = 112/246 (44%), Gaps = 46/246 (18%)
Query: 115 YEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIEDEKI 174
Y++ +G G + KVK+A K VAIK+V+R R F N+F +
Sbjct: 12 YKLGRTIGEGSYSKVKVATSKKYKGTVAIKVVDR---RRAPPDFVNKF-----------L 57
Query: 175 KREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKARGPPLL 234
RE++I++ H H+V + E ++ K+Y+V+E + D+++ R +
Sbjct: 58 PRELSILRGVRHPHIVHVFEFIEVCNG-KLYIVMEAAAT--------DLLQAVQRNGRIP 108
Query: 235 SFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSED-GIVKISDFGVXXXXXXXXXX 293
Q R++F + + YLH ++HRD+K N+LLS D VK++DFG
Sbjct: 109 GVQ-ARDLFAQIAGAVRYLHDHHLVHRDLKCENVLLSPDERRVKLTDFGFGRQAHGYPDL 167
Query: 294 XXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGITLHCLL 353
G+ A+ +PE+ L DP D+W+MG+ L+ ++
Sbjct: 168 STTY-------CGSAAYASPEVLL------GIPYDPKK--------YDVWSMGVVLYVMV 206
Query: 354 FGMLPF 359
G +PF
Sbjct: 207 TGCMPF 212
>CE20167 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD and related
proteins
Length = 722
Score = 84.0 bits (206), Expect = 1e-15
Identities = 86/327 (26%), Positives = 144/327 (43%), Gaps = 74/327 (22%)
Query: 113 NTYEIIEE--LGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIE 170
N Y+++ + LG GQ G V A + + VA+K++++ RF SG E
Sbjct: 422 NLYQVLSDKTLGSGQFGTVYSAIQRHSGKEVAVKVISKE-----------RFSKKGSGAE 470
Query: 171 DEKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIET-KAR 229
++ E+AI+++ H +V L E + + K KI++V+E + GD++E ++
Sbjct: 471 S--MRAEVAILQQTCHPGIVCL-EFMCETKD-KIFVVMEKMN--------GDMLEMILSQ 518
Query: 230 GPPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGI----VKISDFGVXX 285
L+ + T+ + +L L+YLH QGI H D+KP N+LLS+ G KI DFG
Sbjct: 519 ELGRLNSRATKFLLVQILCALKYLHDQGIAHCDLKPENVLLSDMGSNFPQTKICDFGYAR 578
Query: 286 XXXXXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAM 345
GTPA+ PE+ + K D+ W++
Sbjct: 579 FIPESQFRKT--------VVGTPAYLPPEVLQRKGYNKSLDM---------------WSV 615
Query: 346 GITLHCLLFGMLPFISDYELELFDKIVNEPLVF--EPYQKIEQCQVSQVE--CKEEYEEA 401
G+ ++ L G PF E+ ++I N +F EP+ ++E V ++ K E E
Sbjct: 616 GVIIYVTLSGTFPFNEGEEIS--EQIQNASFMFPTEPWSEVEPLAVDLIQKLLKVEIE-- 671
Query: 402 QXXXXXXXXXXXXXRMAIQDAKKHPWV 428
RM+I+ H W+
Sbjct: 672 -------------ARMSIEQCLDHGWL 685
>CE18699 [T] KOG0694 Serine/threonine protein kinase
Length = 1018
Score = 84.0 bits (206), Expect = 1e-15
Identities = 73/275 (26%), Positives = 115/275 (41%), Gaps = 44/275 (16%)
Query: 115 YEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIEDEKI 174
+ +I LG G GKV L++ T A+K++ + R + +E
Sbjct: 690 FRLISVLGRGHFGKVILSQHNPTSNYYALKVLKK-------GDILGRDEVESLMVE---- 738
Query: 175 KREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKARGPPLL 234
KR + + H +V L + ++ +EY G++ D + + RG
Sbjct: 739 KRIFEVSSRARHPFLVNLNGCFQT--NEHVFFCMEYSMGGDLMRHIHDDVFDEVRGCFYA 796
Query: 235 SFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLLSEDGIVKISDFGVXXXXXXXXXXX 294
+ V+LGL++LH II+RDIK NLLL +G VKI+DFG+
Sbjct: 797 AC---------VVLGLDFLHKHNIIYRDIKLDNLLLDREGYVKIADFGLCKENMGPFDKT 847
Query: 295 XXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGITLHCLLF 354
GTP F APE+ L +S I D W +G+ + +L
Sbjct: 848 STF-------CGTPEFLAPEV-----------LSDSSYTRAI----DWWGLGVLIFEMLV 885
Query: 355 GMLPFISDYELELFDKIVNEPLVFEPYQKIEQCQV 389
G PF D E E+FD I++E + + Y +E +
Sbjct: 886 GEPPFSGDDEEEIFDSIISEDVRYPRYLSVESIAI 920
>At5g24430 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 594
Score = 84.0 bits (206), Expect = 1e-15
Identities = 81/323 (25%), Positives = 130/323 (40%), Gaps = 69/323 (21%)
Query: 115 YEIIEELGHGQHGKV---KLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGIED 171
YE+ +E+G G G K + + Q VA+KI+++ K T IED
Sbjct: 143 YELGKEVGRGHFGHTCWAKAKKGKMKNQTVAVKIISKAKM------------TSTLSIED 190
Query: 172 EKIKREIAIMKKCH-HEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKARG 230
++RE+ ++K H H+VK +V +DA + +++V+E C GE+ D I +
Sbjct: 191 --VRREVKLLKALSGHRHMVKFYDVYEDADN--VFVVMELCEGGELL----DRILARGGR 242
Query: 231 PPLLSFQRTREIFRGVLLGLEYLHFQGIIHRDIKPANLLL---SEDGIVKISDFGVXXXX 287
P + +R I +L + H QG++HRD+KP N L +ED I+K+ DFG+
Sbjct: 243 YPEVDAKR---ILVQILSATAFFHLQGVVHRDLKPENFLFTSRNEDAILKVIDFGLSDFI 299
Query: 288 XXXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGI 347
G+ + APE+ S D+W++G+
Sbjct: 300 RYDQRLN--------DVVGSAYYVAPEVL----------------HRSYSTEADMWSIGV 335
Query: 348 TLHCLLFGMLPFISDYELELFDKIVNEPLVFE--PYQKIEQCQVSQVECKEEYEEAQXXX 405
+ LL G PF E +F ++ FE P+ I A+
Sbjct: 336 ISYILLCGSRPFYGRTESAIFRCVLRANPNFEDMPWPSIS-------------PTAKDFV 382
Query: 406 XXXXXXXXXXRMAIQDAKKHPWV 428
RM A HPW+
Sbjct: 383 KRLLNKDHRKRMTAAQALAHPWL 405
>At5g20930 [T] KOG1151 Tousled-like protein kinase
Length = 799
Score = 84.0 bits (206), Expect = 1e-15
Identities = 83/278 (29%), Positives = 125/278 (44%), Gaps = 40/278 (14%)
Query: 111 VLNT-YEIIEELGHGQHGKVKLARDLVTKQLVAIKIVNRHKKRTFNDKFSNRFKTPQSGI 169
VLN+ Y ++ LG G +V A DLV + VA K+ N ++S K QS I
Sbjct: 404 VLNSRYALLNLLGKGGFSEVYKAYDLVDHRYVACKL------HGLNAQWSEEKK--QSYI 455
Query: 170 EDEKIKREIAIMKKCHHEHVVKLIEVLDDAKSRKIYLVLEYCSKGEIKWCPGDVIETKAR 229
RE I K H H+V+L + VLEYCS G ++ +
Sbjct: 456 RHAN--RECEIHKSLVHHHIVRLWDKFH-IDMHTFCTVLEYCS--------GKDLDAVLK 504
Query: 230 GPPLLSFQRTREIFRGVLLGLEYLH--FQGIIHRDIKPANLLLSEDGIVKISDFGVXXXX 287
L + R I ++ GL YL+ Q IIH D+KP N+L E G+ K++DFG+
Sbjct: 505 ATSNLPEKEARIIIVQIVQGLVYLNKKSQKIIHYDLKPGNVLFDEFGVAKVTDFGL--SK 562
Query: 288 XXXXXXXXXXXXXXAKTAGTPAFFAPEICLVEDTIKKFDLDPNSKEPIISFPTDIWAMGI 347
++ AGT + PE F+L +K P+IS D+W++G+
Sbjct: 563 IVEDNVGSQGMELTSQGAGTYWYLPPEC---------FEL---NKTPMISSKVDVWSVGV 610
Query: 348 TLHCLLFGMLPFISDYELELFDKIVNEPLVFEPYQKIE 385
+ +LFG PF D E +I+ E + + +K+E
Sbjct: 611 LFYQMLFGKRPFGHDQSQE---RILREDTIIKA-KKVE 644
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.314 0.132 0.381
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 65,639,481
Number of Sequences: 60738
Number of extensions: 3030086
Number of successful extensions: 11699
Number of sequences better than 1.0e-05: 1247
Number of HSP's better than 0.0 without gapping: 154
Number of HSP's successfully gapped in prelim test: 1093
Number of HSP's that attempted gapping in prelim test: 9056
Number of HSP's gapped (non-prelim): 1632
length of query: 1046
length of database: 30,389,216
effective HSP length: 117
effective length of query: 929
effective length of database: 23,282,870
effective search space: 21629786230
effective search space used: 21629786230
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)