ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIV2341 good U KOG2180 Intracellular trafficking, secretion, and vesicular transport Late Golgi protein sorting complex, subunit Vps53
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIV2341 795025 797433 803
(803 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YJL029c [U] KOG2180 Late Golgi protein sorting complex subunit V... 674 0.0
SPAC3A12.15 [U] KOG2180 Late Golgi protein sorting complex subun... 172 2e-42
7295717 [U] KOG2180 Late Golgi protein sorting complex subunit V... 144 4e-34
Hs21361728 [U] KOG2180 Late Golgi protein sorting complex subuni... 120 6e-27
CE21152 [U] KOG2180 Late Golgi protein sorting complex subunit V... 110 7e-24
At1g50500 [U] KOG2180 Late Golgi protein sorting complex subunit... 99 3e-20
HsM8922802 [U] KOG2180 Late Golgi protein sorting complex subuni... 65 4e-10
>YJL029c [U] KOG2180 Late Golgi protein sorting complex subunit Vps53
Length = 822
Score = 674 bits (1740), Expect = 0.0
Identities = 359/787 (45%), Positives = 514/787 (64%), Gaps = 36/787 (4%)
Query: 1 MISESLEYDPLHDLQQIFSKQESLSDIDNLVLLTEKCKFNLEERVRESNNTSSE--VNSL 58
M+ +++YDPL D+ I +ESL++ID L+ +T K L+E + + N E NS
Sbjct: 1 MLEGTVDYDPLEDITNILFSKESLNNIDELISITRSYKKQLQEDILKEENELKEHPKNSA 60
Query: 59 EDNYDFHKLFEKINSTKSLSQITEATISDLTHDISDLDNAKRNITRSMTCFENLKILSDA 118
E K+F+ T+ +S TE TIS+LT IS LD AK+N+T S+T F+NLKIL+D+
Sbjct: 61 EIEASLRKVFQDFKETQDVSASTELTISNLTEGISYLDIAKKNLTHSLTLFQNLKILTDS 120
Query: 119 YVNSKKYMQAEKYIEMCGPFKVMHSLSVS-FHEYKSLDEFCKFLNQIHRLESDTLLVCER 177
Y+ + + + +M P+K+M SL+ + F YKSLDE L+ I RL+ DTL ++
Sbjct: 121 YIQCNELLSQGSFKKMVSPYKIMCSLAENTFISYKSLDEINYLLSSISRLKGDTLSKIKQ 180
Query: 178 VTKEVLRDGSNSKYDSKT---MKDGICCLADTNKHYKERIVQLCLDSLLYEIKEIFQIDD 234
+ G+ S++D+ +++G C L D + + +++ CLD LL+E+KEIF++DD
Sbjct: 181 NYNALFSGGNISEHDTALTMELREGACELLDCDTSTRAQMIDWCLDKLLFEMKEIFRVDD 240
Query: 235 EAGSLENLSRRYIFFKKVLNNFQSTFSEYFPSEWEIPLKLTDSFFTMTSNDLKTLLKRDL 294
EAGSLENLSRRYI+FKK+LNNF S F++YF +WE+ ++LT +F+ +T DL+TLLKR+
Sbjct: 241 EAGSLENLSRRYIYFKKILNNFNSKFADYFLKDWEMAVRLTTTFYHITHKDLQTLLKREF 300
Query: 295 SGTT-SIDLFMQSLQTTLEFEKYISVKFSH-IYEGKISTCFEPYLKLWVRHQDSSLNAKM 352
SIDLFM +LQ+TL+FEKYI V+FS I E K+S+CFEPYL LWV HQ+ + K
Sbjct: 301 KDKNPSIDLFMTALQSTLDFEKYIDVRFSKKIKEPKLSSCFEPYLTLWVSHQNQMMEKKF 360
Query: 353 LTYLNETKLPA-KNESLVVPSSADLFRTYRHILSQTFSLIEGGNKSTIMVELAVFFVKWL 411
L+Y++E K P+ + ESLV+PSSADLFRTYR +L+QT LI+ +I+ LA FF +WL
Sbjct: 361 LSYMSEPKYPSNETESLVLPSSADLFRTYRSVLTQTLELIDNNANDSILTSLANFFSRWL 420
Query: 412 NEYYEKILKPLLLPEDTQIDDKNEVVKYTVLLVNTADYCANTIDQLQDKLCEYLENDEPN 471
Y +KIL PLLLP++ ++ DK E KYTVLL+NTADYCA TIDQL+DKL E+ N E
Sbjct: 421 QTYSQKILLPLLLPDNIEVQDKLEAAKYTVLLINTADYCATTIDQLEDKLSEFSGNRE-- 478
Query: 472 INKVAAIFEPTRQKYMDLVSGGINLLLNRILKKDLEFVWREFTNTNWANTMVEDYSRYVT 531
K+A F T+ Y DL++ G + LLNR++ DL FVWREF N +W+N +EDYSRY+
Sbjct: 479 --KLANSFTKTKNIYDDLLAKGTSFLLNRVIPLDLNFVWREFINNDWSNAAIEDYSRYMV 536
Query: 532 TLQSIL-LPT---------RSENSTFYSTVSQFNRDLYGWNFIDKTIDLIAISFESQIIK 581
TL+S+L +P + + ST +SQFNRD+Y WNF+DK ID+I +F S I+
Sbjct: 537 TLKSVLKMPALTDASIKQQQEQPSTLAFILSQFNRDVYKWNFLDKVIDIITTNFVSNTIR 596
Query: 582 LLKPALPYGTLNSKRQFDVKQVINIAEXXXXXXXXXXXXXHSLPESLP-----QHDTSAK 636
LL+P P+ SKR+F+ + V+NI E H+LPES+ + +TS K
Sbjct: 597 LLQPVPPFSLAGSKRKFETRTVVNIGEQLLLDLELLKEIFHTLPESVSNDSDLRENTSYK 656
Query: 637 RVTKHIDSNVEKLMHLLKLLVSPIDPDTTYLETYYAITASQNTNSNFWAFILALKGVPWD 696
RV +H D+N+++L+ +KLL++P+D Y ETY +T + N +S W+F+LALKG+PWD
Sbjct: 657 RVKRHADNNIDQLLKFIKLLMAPLDSADDYYETYSKLT-NNNPDSAVWSFVLALKGIPWD 715
Query: 697 LALWKRVWSEFQQSDDDT-QPMKPD---DLI---FNPRELQNFIYNLSRVSDPSWKTFLE 749
LALWK++WS + DDT + +PD DL ++ L F NL+R+ DP+W F+
Sbjct: 716 LALWKKLWSAYNLETDDTDEGSRPDSNRDLFIFKWDKVLLGQFENNLARMQDPNWSKFVR 775
Query: 750 EDLKIKP 756
+DLKI P
Sbjct: 776 QDLKISP 782
>SPAC3A12.15 [U] KOG2180 Late Golgi protein sorting complex subunit Vps53
Length = 756
Score = 172 bits (436), Expect = 2e-42
Identities = 178/755 (23%), Positives = 322/755 (42%), Gaps = 108/755 (14%)
Query: 1 MISESLEYDPLHDLQQIFSK--QESLSDIDNLVLLTEKCKFNLEERVRESNNTSSEVNSL 58
++ E + YD L L+ S+ QES+ +D E K ++ E++ + N++
Sbjct: 28 LLPEDITYDDLGSLRLSLSERLQESVKKLDANKKTYEDAKLSMGEKMDDLNSS------- 80
Query: 59 EDNYDFHKLFEKINSTKSLSQITEATISDLTHDISDLDNAKRNITRSMTCFENLKILSDA 118
L +++++ +S+++ T+++I +T +I +LD AK+N+ SMT + L++L A
Sbjct: 81 -----IVSLLQELSTLQSVAENTQSSIVQMTSEIKNLDFAKQNLATSMTMLKRLQMLVTA 135
Query: 119 YVNSKKYMQAEKYIEMCGPFKVMHSLSVSFHEYKSLDEFCKFLNQIHRLES-------DT 171
Y + Q +K+ E + L F +Y+S++ I + DT
Sbjct: 136 YEKLRTLRQNQKFGEAISLMQATLQLLNFFKKYRSVERIASLSRSISEFQKSFYEQVFDT 195
Query: 172 LLVCERVTKEVLRDGSNSKYDSKTMKDGICCLADTNK-HYKERIVQLCLDSLLYEIKEIF 230
+ KE G S + + + +C D E +++ L + ++F
Sbjct: 196 FQ--SQFKKESGMRGGFSPSSVQYLNE-LCRFIDIFAGDPPESVIRWYCRHQLEDFMKVF 252
Query: 231 QIDDEAGSLENLSRRYIFFKKVLNNFQSTFSEYFPSEWEIPLKLTDSFFTMTSNDLKTLL 290
+ ++EAGSLENL RRY +FKK+L + FP W++ +L + F T NDL LL
Sbjct: 253 RENEEAGSLENLPRRYTWFKKLLQTYDQLHKPIFPPHWKVDFRLYEVFCEETKNDLSKLL 312
Query: 291 KRDLSGTTSIDLFMQSLQTTLEFEKYI-------SVKFSHIYEGK-------ISTCFEPY 336
K D S+ +F+ SL+ TLEFE +I +F+ +E K +S+ FEP+
Sbjct: 313 KDD---RLSLQVFVASLEQTLEFESFIDHRFYNTKSRFNSNFEPKERQAYNALSSVFEPH 369
Query: 337 LKLWVRHQDSSLNAKMLTYLNETKLPAKNESLVVPSSADLFRTYRHILSQTFSLIEGGNK 396
L+ Q + + E + S V+ SS LF+ YR L+Q L +
Sbjct: 370 YTLYFNQQSQEFSILFENFALEKQTSTDESSQVLSSSIKLFQAYRKTLTQFVRL----TR 425
Query: 397 STIMVELAVFFVKWLNEYYEKILKPLLLPEDTQID----DKNEVVKYTVLLVNTADYCAN 452
S+ +V L F+KWL Y TQ++ ++ K + +NTA+Y
Sbjct: 426 SSPLVGLKNLFIKWLRRY-------------TQVELLDYQESSTFKDIAIRLNTAEYIYR 472
Query: 453 TIDQLQDKLCEYLE---NDEPNINKVAAIFEPTRQKYMDLVSGGINLLLNRIL----KKD 505
T +L+ + E D+ + ++V + +R + +G +LN L K D
Sbjct: 473 TTIELEKRFQEISNKEFKDKMSFSEVLEVISSSRGTLLKFATGKFENVLNSDLEPLSKMD 532
Query: 506 LEFVWREFTNTNWANTMVEDYSRYVTTLQSILLPTRSENSTFYSTVSQFNRDLYGWNFID 565
L+ + V D S YV + SE F S V + +++ NF D
Sbjct: 533 LKNI-----------ETVGDQSSYVGGAVQNMTAKASE---FLSVV---DLNMFARNFCD 575
Query: 566 KTIDLIAISFESQIIKLLKPALPYGTLNSKRQFDVKQVINIAEXXXXXXXXXXXXXHSLP 625
++ + SF Q + + A P + AE LP
Sbjct: 576 RSCE----SFTRQFLNAIYLAKPISEVG-------------AEQLLLDLYSFKNALLKLP 618
Query: 626 ESLPQHDTSAKRVTKHIDSNVEKLMHLLKLLVSPIDPDTTYLETYYAITASQNTNSNFWA 685
+ L Q + H+ + + +LK L++P P ++++Y + ++ + +
Sbjct: 619 D-LKQDYSITDSYINHLTIFMGYIETVLKTLLTPASPKAGFIQSYIFLVKDRSVTN--FT 675
Query: 686 FILALKGV-PWDLALWKRVWSEFQQSDDDTQPMKP 719
+L LKGV D++ + + +S+F + + P
Sbjct: 676 VLLELKGVGKSDISSFLQQFSDFVKKTPQLEESSP 710
>7295717 [U] KOG2180 Late Golgi protein sorting complex subunit Vps53
Length = 868
Score = 144 bits (364), Expect = 4e-34
Identities = 131/610 (21%), Positives = 267/610 (43%), Gaps = 98/610 (16%)
Query: 7 EYDPLHDLQQIFSKQESLSDIDNLVLLTEKCKF-----NLEERVRESNNTSSE--VNSLE 59
+++ + + Q+F ++SL+ ID + + C+ N+ VR NT + + E
Sbjct: 44 DFNTVDYINQLFPNEQSLAGIDETIQKMQ-CEVSLIDDNIRSVVRGQTNTGQDGQLALCE 102
Query: 60 DNYDFHKLFEKINSTKSLSQITEATISDLTHDISDLDNAKRNITRSMTCFENLKILSDAY 119
LF I K+ ++ TE + ++T DI LD AKRN+T ++T +L +L
Sbjct: 103 AQKVISSLFSHIIDVKTRAERTEEMVKEITRDIKQLDCAKRNLTAAITTLNHLHMLVGGI 162
Query: 120 VNSKKYMQAEKYIEMCGPFKVMHSLSVSFHEYKSLDEFCKFLNQIHRLESDTLLVCERVT 179
+ K ++ Y E+ P + + ++ F ++ ++E + +++ + + +++T
Sbjct: 163 ESLNKLIERRSYGEILNPLQAITEVNQHFQQFSDIEEIKNLSQSVDKIQ---VTLAQQIT 219
Query: 180 KEVLRDGSNSKYDSKTMKDGICCLADTNK-------HYKERIVQLCLDSLLYEIKEIFQI 232
++ S + G+ LAD K K+ +++ + L E +F
Sbjct: 220 EDFKEAFSAKPSSQNQHRLGLNQLADACKVMSVLDPKVKKELLKWFIAQQLEEYTHLFHE 279
Query: 233 DDEAGSLENLSRRYIFFKKVLNNFQSTFSEYFPSEWEIPLKLTDSFFTMTSNDLKTLLKR 292
+ + L+ + +RY + K+ L +F+ + FP +WE+ ++T F T L ++ +
Sbjct: 280 NQDIAWLDKIDKRYAWLKRHLLDFEDKYGPVFPLDWEVSERITVEFCRQTREQLAQIMAK 339
Query: 293 DLSGTTSIDLFMQSLQTTLEFEKYISVKFS---------------------------HIY 325
+ + L + ++ T FE+ +S +F+ ++
Sbjct: 340 -RTNEIDVRLLLFAINKTQAFEQLLSKRFTGVTLGAQPTDKARVLAEPTTTDGAVGLTVF 398
Query: 326 EGKISTCFEPYLKLWVRHQDSSLNAKMLTYLNETKLP---AKNESLVVPSSADLFRTYRH 382
+I CF+P+L +++R D +L+ M ++ ++ P A+ ++ V PSS DLF Y+
Sbjct: 399 HDQIGQCFKPHLDIYIRSIDRNLSELMDKFVEMSREPYKFAEAKTTVYPSSGDLFVFYKK 458
Query: 383 ILSQTFSLIEGGNKSTIMVELAVFFVKWLNEYYEKILK---PLLLPE------------- 426
+ Q L + M +LA+ F K+L EY K+L+ P L+P
Sbjct: 459 CMVQCNQL----SNEQPMYDLALVFKKYLREYASKVLEGSTPKLVPATTSSSIGKSVSLL 514
Query: 427 ----------------------DTQIDDKNEVVKYTVLLVNTADYCANTIDQLQDKLCEY 464
DTQ ++++V+ +L T +YC T+ QL+DKL E
Sbjct: 515 TRDMQNLSTAAGQVFHNFLKEGDTQRFARDDLVRICCVL-TTGEYCLETVQQLEDKLKEK 573
Query: 465 LENDEPNINKVAAIFEPTRQKYMDLVSGGINLLLNRILKKDLEFVWREFTNTNWAN-TMV 523
+ + ++K+ E + + ++S I LL+ + L+ E + W + V
Sbjct: 574 VTS--AYVSKIDMSEE--KDVFHRIISNCIQLLV-QDLEAGCEASLQAMAKVQWQHINNV 628
Query: 524 EDYSRYVTTL 533
D S ++++L
Sbjct: 629 GDQSAFISSL 638
>Hs21361728 [U] KOG2180 Late Golgi protein sorting complex subunit Vps53
Length = 670
Score = 120 bits (302), Expect = 6e-27
Identities = 137/613 (22%), Positives = 255/613 (41%), Gaps = 120/613 (19%)
Query: 14 LQQIFSKQESLSDID-------NLVLLTEKCKFNLEERVRESNNTSSEVNSLEDNYDFHK 66
++Q+F Q+ L D N + TE+ N++E V N ++ L+DN
Sbjct: 27 IEQVFPSQDPLDRADFNAVEYINTLFPTEQSLANIDEVV---NKIRLKIRRLDDN----- 78
Query: 67 LFEKINSTKSLSQITEATISDLTHDISDLDNAKRNITRSMTCFENLKILSDAYVNSKKYM 126
+ + ++ Q + ++T DI LD+AKR++T S+T +L +L+ + +
Sbjct: 79 IRTVVRGQTNVGQ-DGRQVKEITRDIKQLDHAKRHLTTSITTLNHLHMLAGGVDSLEAMT 137
Query: 127 QAEKYIEMCGPFKVMHSLSVSFHEYKSLDEFCKFLNQIHRLESDTLLVCERVTKEVLRDG 186
+ +Y E+ + + ++ FH+Y + QI +L + +++L D
Sbjct: 138 RRRQYGEVANLLQGVMNVLEHFHKYMGIP-------QIRQLSERVKAAQTELGQQILADF 190
Query: 187 SNSKYDSKTMKDG--------ICCLADT-NKHYKERIVQLCLDSLLYEIKEIFQIDDEAG 237
+ T + G C +A+ + K+ I++ + L E +FQ + +
Sbjct: 191 EEAFPSQGTKRPGGPSNVLRDACLVANILDPRIKQEIIKKFIKQHLSEYLVLFQENQDVA 250
Query: 238 SLENLSRRYIFFKKVLNNFQSTFSEYFPSEWEIPLKLTDSFFTMTSNDLKTLLKRDLSGT 297
L+ + RRY + K+ L +++ + FP EW + ++ F +T +L ++ R +
Sbjct: 251 WLDKIDRRYAWIKRQLVDYEEKYGRMFPREWCMAERIAVEFCHVTRAELAKIM-RTRAKE 309
Query: 298 TSIDLFMQSLQTTLEFEKYISVKFS----------------------------------- 322
+ L + ++Q T FE +++ +FS
Sbjct: 310 IEVKLLLFAIQRTTNFEGFLAKRFSGCTLTDGTLKKLESPPPSTNPFLEDEPTPEMEELA 369
Query: 323 ----------------HIYEGKISTCFEPYLKLWVRHQDSSLNAKMLTYLNETKL---PA 363
+ + G +S CFEP+L +++ QD +L + ++ + K P
Sbjct: 370 TEKGDLDQPKKPKAPDNPFHGIVSKCFEPHLYVYIESQDKNLGELIDRFVADFKAQGPPK 429
Query: 364 KNE---SLVVPSSADLFRTYRHILSQTFSLIEGGNKSTIMVELAVFFVKWLNEYYEKILK 420
N V+PS ADLF Y+ + Q L G M+ L F K+L EY KIL
Sbjct: 430 PNTDEGGAVLPSCADLFVYYKKCMVQCSQLSTG----EPMIALTTIFQKYLREYAWKILS 485
Query: 421 PLLLPEDT------------QIDDKNEVVKYTV-------LLVNTADYCANTIDQLQDKL 461
LP+ T + + +EV K+T+ +++TA+YC T QL++KL
Sbjct: 486 G-NLPKTTTSSGGLTISSLLKEKEGSEVAKFTLEELCLICNILSTAEYCLATTQQLEEKL 544
Query: 462 CEYLENDEPNINKVAAIFEPTRQKYMDLVSGGINLLLNRILKKDLEFVWREFTNTNWANT 521
E + D I ++ E + ++S I LL+ + L + + W N
Sbjct: 545 KEKV--DVSLIERINLTGE--MDTFSTVISSSIQLLV-QDLDAACDPALTAMSKMQWQNV 599
Query: 522 -MVEDYSRYVTTL 533
V D S YVT++
Sbjct: 600 EHVGDQSPYVTSV 612
>CE21152 [U] KOG2180 Late Golgi protein sorting complex subunit Vps53
Length = 808
Score = 110 bits (276), Expect = 7e-24
Identities = 114/513 (22%), Positives = 221/513 (42%), Gaps = 45/513 (8%)
Query: 14 LQQIFSKQESLSDIDNLVLLTEKCKFNLEERVRESNNTSSEVNSLEDNYDFHKLFEKINS 73
+ ++F ++SL+ +D+++ E L+ + T++ V+ + H I
Sbjct: 38 INELFPTEQSLTQLDSIIASVEGEIGELDNELAYLVETNANVSERGEEALKHAQDAMIEL 97
Query: 74 TKSLSQITEAT------ISDLTHDISDLDNAKRNITRSMTCFENLKILSDAYVNSKKYMQ 127
KS+ I E T + ++T DI LD AKRN+T S+T +L IL + ++
Sbjct: 98 EKSIGSIRERTKSSDEIVREMTRDIKQLDIAKRNLTASITTLHHLHILLTGVESLGAWVD 157
Query: 128 AEKYIEMCGPFKVMHSLSVSFHEYKSLDEFCKFLNQIHRLESDTLLVCERVTKEVLRDGS 187
+ Y + + ++ F YK D+ Q+ +L++ + + K + G
Sbjct: 158 KKDYSSIARQLPAILNVLQLFDAYKESDQIANLSGQLDKLKASLTIQLAKDLKNAFQTGQ 217
Query: 188 NSKYDSKTMKDGICCLADTNKHYKERIVQLCLDSLLYEIKEIFQIDDEAGSLENLSRRYI 247
S + D A + KE V+ ++ L E I+ ++E L+ + RY
Sbjct: 218 L----SDRITDMCRVAAALEGNVKENFVKWFIEQQLSEYVIIYADNEEGAWLDKVDDRYK 273
Query: 248 FFKKVLNNFQ-STFSEYFPSEWEIPLKLTDSFFTMTSNDLKTLLKRDLSGTTSIDLFMQS 306
+F + L +F+ + S FP++W + +LT F T+T + L ++ R L +
Sbjct: 274 WFVRKLTDFERAGLSNIFPADWHMGRRLTSEFCTVTRDILYRIMTRRRQ-DLDWKLLGHA 332
Query: 307 LQTTLEFEKYISVKFSH----IYEGKISTCFEPYLKLWVRHQDSSLNAKMLTYLNETK-- 360
+Q T FE ++ +F +E I + F+ +L +++ Q+ +LN + T ++ +
Sbjct: 333 IQHTKMFEALLTKRFPEKDGISFEKAIWSVFDTFLDVFINAQEKTLNEFLDTCASKIRSG 392
Query: 361 --LPAKNES---LVVPSSADLFRTYRHILSQTFSLIEGGNKSTIMVELAVFFVKWLNEYY 415
P++ S + PSSAD+F + +++++ L ++ ++ + V+ Y
Sbjct: 393 EEKPSRESSTHAVPFPSSADMFLLLKKVITESSKL---SSEPDALIRDVIGVVRVCLRGY 449
Query: 416 EKILKPLLLPE--DTQIDDKN------EVVKYTVL----------LVNTADYCANTIDQL 457
LP Q N E + Y L ++ TAD+CA T QL
Sbjct: 450 ATSCLVAFLPSLGSQQSGAANLFSLIREEIAYPRLTPDQQFLVCCILATADWCAETSIQL 509
Query: 458 QDKLCEYLENDEPNINKVAAIFEPTRQKYMDLV 490
Q+KL + + + + + A + T Q LV
Sbjct: 510 QEKLSQRIPGVDIS-QETEAFYSITNQSLQVLV 541
>At1g50500 [U] KOG2180 Late Golgi protein sorting complex subunit Vps53
Length = 822
Score = 98.6 bits (244), Expect = 3e-20
Identities = 156/754 (20%), Positives = 297/754 (38%), Gaps = 117/754 (15%)
Query: 3 SESLEYDPLHDLQQIFSKQESLSDIDNLVLLTE----KCKFNLEERVRESNNTSSEVNSL 58
S SL +D + L+ IF SL+ ++ L+ + + ++ VR+ +N+ ++
Sbjct: 25 SYSLYFD--YGLELIFVAAASLTGVEPLMQKIQGEIRRVDASILSAVRQQSNSGTKAK-- 80
Query: 59 EDNYD----FHKLFEKINSTKSLSQITEATISDLTHDISDLDNAKRNITRSMTCFENLKI 114
ED D +L KI KS ++ +EA + ++ DI LD AK+NIT ++T L +
Sbjct: 81 EDLADATRAVEELSHKIQEIKSKAEQSEAMVQEICRDIKKLDFAKKNITTTITALHRLTM 140
Query: 115 LSDAYVNSKKYMQAEKYIEMCGPFKVMHSLSVSFHEYKSLDEFCKFLNQIHRLESDTLLV 174
L A + +Y E + ++ L F Y+ + + + +++ ++ ++
Sbjct: 141 LVSAVEQLQVMASKRQYKEAAAQLEAVNQLCNHFEAYRDVPKITELREKLNNIKQ---IL 197
Query: 175 CERVTKEVLRDGSNSKYDSKTMKDGI---CCLADT-NKHYKERIVQLCLDSLLYEIKEIF 230
V + G+ + + + + C + D +E +V L ++IF
Sbjct: 198 KSHVFSDFSSLGTGKETEETNLLQKLSDSCLVVDALEPSVREELVNNFCSRELTSYEQIF 257
Query: 231 QIDDEAGSLENLSRRYIFFKKVLNNFQSTFSEYFPSEWEIPLKLTDSFFTMTSNDLKTLL 290
+ E L+ RRY + K+ + + + + FP+ W +P +L F T ++++L
Sbjct: 258 E-GAELAKLDKTERRYAWIKRRIRTNEEIW-KIFPASWHVPYRLCIQFCKQTRKQVESIL 315
Query: 291 KRDLSGTTSIDLFMQSLQTTLEFEKYISVKFSHIYEGKISTCFEPYLKLWVRHQDSSLNA 350
++ + + + +LQ+T+EFEK + KF G + E ++ +D+S N
Sbjct: 316 V-NMKEKPVVAILLLALQSTVEFEKELEKKFG---GGVPTKDIEDDIEEIGTWEDNSQNI 371
Query: 351 KMLTYLNETKLPAK----------NESLVVPSSADLFR---------------------- 378
+ E K A N+ L V + FR
Sbjct: 372 SKIRKKYEKKFAASQETEENEKTGNKDLSVTGAGFNFRGMISSCFEPHLTPYIELEEKTL 431
Query: 379 --TYRHILSQTFSLIEGGNKSTIMVELAVFFVKWLNEYYEKILKPLLLPE---------- 426
I+ + +E G+++ ++ F + L Y K+ LP+
Sbjct: 432 MDDLEKIVQEESWDVEDGSQNNVLSSSTQVFQRVLKAYATKLF--FKLPKGGTGIVAAAT 489
Query: 427 --DTQIDDKNEVVKYTVLLVNTADYCANTIDQLQDKLCEYLE---NDEPNINKVAAIFEP 481
D QI + +VN+A+YC T +L + + E ++ D ++++V F
Sbjct: 490 GMDGQIKVSERDERVICYIVNSAEYCHKTSGELAENVSEIIDPHYADGVDMSEVQDEFSA 549
Query: 482 TRQKYMDLVSGGINLLLNRILKKDLEFVWREFTNTNWAN-TMVEDYSRYVTTLQSILLPT 540
K + + L+L K D E T W+ V D S YV + ++L
Sbjct: 550 VITKAL------VTLVLGLETKFDTEMA--VMTRVPWSTLESVGDQSGYVNGINTVL--- 598
Query: 541 RSENSTFYSTVSQFNRDLYGWNFIDKTIDLIAISFESQIIKLLKPALPYGTLNSKRQFDV 600
S + + +Y F+DK + F + I F
Sbjct: 599 ----SGSIPVLGKLLTPVYFQFFLDKLASSLGPRFYANI------------------FRC 636
Query: 601 KQVINI-AEXXXXXXXXXXXXXHSLPESLPQHDTSAKRVTKHIDSNVEKLMHLLKLLVSP 659
KQ+ A+ +P SL + ++A +K + + + LLK+++SP
Sbjct: 637 KQLSETGAQQMLLDTQAVKSILLEIP-SLARQTSTAASYSKFVSREMSRAEALLKVILSP 695
Query: 660 IDPDTTYLETYYAITASQNTNSNFWAFILALKGV 693
ID + +TY A+ + T F IL LKG+
Sbjct: 696 ID---SVADTYRAL-FPEGTPMEFQR-ILELKGL 724
>HsM8922802 [U] KOG2180 Late Golgi protein sorting complex subunit Vps53
Length = 368
Score = 65.1 bits (157), Expect = 4e-10
Identities = 67/235 (28%), Positives = 107/235 (45%), Gaps = 36/235 (15%)
Query: 325 YEGKISTCFEPYLKLWVRHQDSSLNAKMLTYLNETKL---PAKNE---SLVVPSSADLFR 378
+ G +S CFEP+L +++ QD +L + ++ + K P N V+PS ADLF
Sbjct: 86 FHGIVSKCFEPHLYVYIESQDKNLGELIDRFVADFKAQGPPKPNTDEGGAVLPSCADLFV 145
Query: 379 TYRHILSQTFSLIEGGNKSTIMVELAVFFVKWLNEYYEKILKPLLLPEDT---------- 428
Y+ + Q L G M+ L F K+L EY KIL LP+ T
Sbjct: 146 YYKKCMVQCSQLSTG----EPMIALTTIFQKYLREYAWKILSG-NLPKTTTSSGGLTISS 200
Query: 429 --QIDDKNEVVKYTV-------LLVNTADYCANTIDQLQDKLCEYLENDEPNINKVAAIF 479
+ + +EV K+T+ +++TA+YC T QL++KL E + D I ++
Sbjct: 201 LLKEKEGSEVAKFTLEELCLICNILSTAEYCLATTQQLEEKLKEKV--DVSLIERINLTG 258
Query: 480 EPTRQKYMDLVSGGINLLLNRILKKDLEFVWREFTNTNWANT-MVEDYSRYVTTL 533
E + ++S I LL+ + L + + W N V D S YVT++
Sbjct: 259 E--MDTFSTVISSSIQLLV-QDLDAACDPALTAMSKMQWQNVEHVGDQSPYVTSV 310
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.318 0.134 0.386
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 46,381,777
Number of Sequences: 60738
Number of extensions: 1988232
Number of successful extensions: 6089
Number of sequences better than 1.0e-05: 7
Number of HSP's better than 0.0 without gapping: 3
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 6048
Number of HSP's gapped (non-prelim): 13
length of query: 803
length of database: 30,389,216
effective HSP length: 115
effective length of query: 688
effective length of database: 23,404,346
effective search space: 16102190048
effective search space used: 16102190048
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)