ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIV2349 good D KOG0834 Cell cycle control, cell division, chromosome partitioning CDK9 kinase-activating protein cyclin T
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIV2349 801309 800341 -323
(323 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YJL006c [D] KOG0834 CDK9 kinase-activating protein cyclin T 365 e-101
SPBC530.13 [D] KOG0834 CDK9 kinase-activating protein cyclin T 82 1e-15
Hs18583591 [D] KOG0834 CDK9 kinase-activating protein cyclin T 62 1e-09
At5g48640 [K] KOG0794 CDK8 kinase-activating protein cyclin C 52 1e-06
7302150 [D] KOG0834 CDK9 kinase-activating protein cyclin T 52 2e-06
At5g48630 [K] KOG0794 CDK8 kinase-activating protein cyclin C 51 3e-06
>YJL006c [D] KOG0834 CDK9 kinase-activating protein cyclin T
Length = 323
Score = 365 bits (937), Expect = e-101
Identities = 171/309 (55%), Positives = 229/309 (73%), Gaps = 1/309 (0%)
Query: 4 QSDLILSRPYLTKSQLQKSQKYNIPDRRTYNQKRILVFKYLCQLCVHLKLPRKVLEATMY 63
+S L SRP+L+K Q+Q++QK I D R YNQK++ VFK+L LCV LK PRK LE +Y
Sbjct: 6 ESQLFFSRPFLSKRQIQRAQKNTISDYRNYNQKKLAVFKFLSDLCVQLKFPRKTLETAVY 65
Query: 64 FYHRYHAFNKFETEMCYDVGTSCLFLSCKQVETFKRLGEVCSTALKIRNVPRVTPDMVDA 123
FY RYH FN+FETE+CY V TSCL L CK+VET K+ ++C+ +L++RNV ++ D+++
Sbjct: 66 FYQRYHLFNRFETEVCYTVATSCLTLGCKEVETIKKTNDICTLSLRLRNVVKINTDILEN 125
Query: 124 FKKRVMQMELRVLETCSFDYRVNNEVHIDEFIVKIGRELSLPYSCCRLAWLIAFDVLKLE 183
FKKRV Q+ELR+LE+CSFDYRVNN VHIDE+++KIGRELS Y C LAW+IA+D LKLE
Sbjct: 126 FKKRVFQIELRILESCSFDYRVNNYVHIDEYVIKIGRELSFDYKLCNLAWVIAYDALKLE 185
Query: 184 LLITVPPHTIALAVLKLACELLNETKWPNVRYNLFETDAASFHEAYFDILNFYINVFDAC 243
++ +P H+IALA+LK+A ELL+ W + RY+LFETD S +EAYFDI+NFYIN FD C
Sbjct: 186 TILVIPQHSIALAILKIAYELLDNKNWSSKRYSLFETDEKSVNEAYFDIVNFYINSFDMC 245
Query: 244 DLKDHETVKSLNLKIETFIEIKKTAGPEQGL-KVDPIALDKDDYVSKERNFAVKERRYVL 302
DL+ H L + +E F+E+KK AGPE GL ++ L+ D Y++ R+ V+ERRYVL
Sbjct: 246 DLQRHLPADLLPIGVERFMELKKNAGPESGLPQIPDHLLNADPYITITRDNNVQERRYVL 305
Query: 303 NQNSLQEES 311
+ + ES
Sbjct: 306 SLELINGES 314
>SPBC530.13 [D] KOG0834 CDK9 kinase-activating protein cyclin T
Length = 325
Score = 82.0 bits (201), Expect = 1e-15
Identities = 71/294 (24%), Positives = 130/294 (44%), Gaps = 17/294 (5%)
Query: 9 LSRPYLTKSQLQKSQKYNIPDRRTYNQKRILVFKYLCQLCVHLKLPRKVLEATMYFYHRY 68
+S PY ++ ++ + P N R+ F ++ L LK P + M Y R+
Sbjct: 13 MSHPYYSEKEISRILSTRDPKE---NNLRMQAFAWISTLSKTLKFPVRTSGLAMLLYSRF 69
Query: 69 HAFNKFETEMCYDVGTSCLFLSCKQVETFKRLGEVCSTALKIRNVPRVTPDMVDAF-KKR 127
F + T+CL ++ K +T K+ ++ L + + VDA +KR
Sbjct: 70 QLFFPVNEIPLLECATACLVVASKIEDTAKKFRDI----LLAHYLQKHPGSEVDAHSQKR 125
Query: 128 VMQMELRVLETCSFDYRVNNEVHIDEFIVKIGRELSLPYSCCRLAWLIAFDVLKLELLIT 187
++ +E LE FD+RV H ++VK + L S +AW + D K ++
Sbjct: 126 ILGLERMTLELICFDFRVR---HPHNYMVKFAKSLKFSSSTASIAWNVCTDAYKTYTMLK 182
Query: 188 VPPHTIALAVLKLACELLNETKWPNVRYNLFETDAASFHEAYFDILNFYINVF-DACDLK 246
P H +A+A + +AC+ L + P + + F A + DIL+ Y++ C
Sbjct: 183 YPAHIVAVASISIACK-LQQLPQPIIPRSFFAPPALT-EAVIADILDLYMHYQPHTCIGN 240
Query: 247 DHETVKSLNLKIETFIEIKKTAGPEQGLKVDPIALD-KDDYVSKERNFAVKERR 299
+ T K L L ++ K + P++ ++DP + D+Y +E N ++E +
Sbjct: 241 MYTTEKLLGLCVDFQRAQKNSGRPQKPPQIDPHSSSLADEY--RESNKRLQESK 292
>Hs18583591 [D] KOG0834 CDK9 kinase-activating protein cyclin T
Length = 354
Score = 61.6 bits (148), Expect = 1e-09
Identities = 47/167 (28%), Positives = 80/167 (47%), Gaps = 8/167 (4%)
Query: 42 KYLCQLCVHLKLPRKVLEATMYFYHRYHAFNKFETEMCYDVGTSCLFLSCKQVETFKRLG 101
+++ + L L L + ++HR++ F+ F+ Y G CLFL+ K ET K+
Sbjct: 55 RFIFDVGTRLGLHYDTLATGIIYFHRFYMFHSFKQFPRYVTGACCLFLAGKVEETPKKCK 114
Query: 102 EVCSTALKIRNVPRVTPDMVDAFKKRVMQMELRVLETCSFDYRVNNEVHIDEFIVKIGRE 161
++ TA + N + D K+ VM +E +L+T FD +V H +F++K ++
Sbjct: 115 DIIKTARSLLNDVQF-GQFGDDPKEEVMVLERILLQTIKFDLQVE---HPYQFLLKYAKQ 170
Query: 162 L----SLPYSCCRLAWLIAFDVLKLELLITVPPHTIALAVLKLACEL 204
L + ++AW D L L + P IA+AV+ LA L
Sbjct: 171 LKGDKNKIQKLVQMAWTFVNDSLCTTLSLQWEPEIIAVAVMYLAGRL 217
>At5g48640 [K] KOG0794 CDK8 kinase-activating protein cyclin C
Length = 259
Score = 52.0 bits (123), Expect = 1e-06
Identities = 49/226 (21%), Positives = 100/226 (43%), Gaps = 23/226 (10%)
Query: 43 YLCQLCVHLKLPRKVLEATMYFYHRYH---AFNKFETEMCYDVGTSCLFLSCKQVETFKR 99
++ +L H+K+ ++V+ + + R + + +FE + V +CL+L+ K E+ +
Sbjct: 47 HIMKLAQHIKVRQRVVATAITYMRRVYIRKSMVEFEPRL---VALTCLYLASKAEESIVQ 103
Query: 100 LGEVCSTALKIRNVPRVTPDMVDAFK-KRVMQMELRVLETCSF------DYRVNNEVHID 152
+ ++ N+ PD + ++ K ++ ME++VLE + YR +E D
Sbjct: 104 ARNLVFYIKRLCNIFFFYPDEYNKYELKDILGMEMKVLEALDYYLVVFHPYRSLSEFLQD 163
Query: 153 EFIVKIGRELSLPYSCCRLAWLIAFDVLKLELLITVPPHTIALAVLKLACELLNETKWPN 212
+ + ++ W I D K++L++ PP+ IALA + +A ++ K
Sbjct: 164 AALNDVNMN--------QITWGIVNDTYKMDLILVHPPYRIALACIYIAS--VHREKDIT 213
Query: 213 VRYNLFETDAASFHEAYFDILNFYINVFDACDLKDHETVKSLNLKI 258
+ D +IL+FY N + K + L LK+
Sbjct: 214 AWFEDLHEDMNLVKNIAMEILDFYENYRTITEEKVNSAFSKLALKL 259
>7302150 [D] KOG0834 CDK9 kinase-activating protein cyclin T
Length = 381
Score = 51.6 bits (122), Expect = 2e-06
Identities = 41/171 (23%), Positives = 78/171 (44%), Gaps = 16/171 (9%)
Query: 42 KYLCQLCVHLKLPRKVLEATMYFYHRYHAFNKFETEMCYDVGTSCLFLSCKQVETFKRLG 101
+++ + + L + + ++HR++ F+ F + Y CLF + K ET K+
Sbjct: 35 RFIMECGTKMGLGHNTMATGVVYFHRFYMFHSFRSFPRYVTACCCLFFAGKVEETPKKCR 94
Query: 102 EVCSTALKIRNVPRVTPDMVDAF----KKRVMQMELRVLETCSFDYRVNNEVHIDEFIVK 157
++ TA I +T + +F K+ VM +E +L+T FD +V H F++K
Sbjct: 95 DIIKTARGI-----LTDNYFYSFGDDPKEEVMTLERILLQTIKFDLQVE---HPYTFLLK 146
Query: 158 IGR----ELSLPYSCCRLAWLIAFDVLKLELLITVPPHTIALAVLKLACEL 204
+ + ++AW D L + + P IA+A++ LA +L
Sbjct: 147 YAKCFKGDQQKLQKMVQMAWNFVNDSLSTVVCLQWEPEIIAVALIHLASKL 197
>At5g48630 [K] KOG0794 CDK8 kinase-activating protein cyclin C
Length = 253
Score = 50.8 bits (120), Expect = 3e-06
Identities = 46/201 (22%), Positives = 94/201 (45%), Gaps = 19/201 (9%)
Query: 43 YLCQLCVHLKLPRKVLEATMYFYHRYH---AFNKFETEMCYDVGTSCLFLSCKQVETFKR 99
Y+ +L H+K+ ++V+ + + R + + ++E + V +CL+L+CK E+
Sbjct: 47 YISKLAQHIKIRQRVVATAVTYMRRVYTRKSLTEYEPRL---VAPTCLYLACKAEES--- 100
Query: 100 LGEVCSTALKIRNVPRVTPDMVDAFK-KRVMQMELRVLETCSFDYRVNNEVH-IDEFIVK 157
V L + + ++ D ++ K +++ME++VLE +F V + + EF+
Sbjct: 101 ---VVHAKLLVFYMKKLYADEKFRYEIKDILEMEMKVLEALNFYLVVFHPYRSLPEFLQD 157
Query: 158 IGRELSLPYSCCRLAWLIAFDVLKLELLITVPPHTIALAVLKLACELLNETKWPNVRYNL 217
G + S L W + D +++L++ PP I LA + +A +++ K +
Sbjct: 158 SGINDT---SMTHLTWGLVNDTYRMDLILIHPPFLITLACIYIAS--VHKEKDIKTWFEE 212
Query: 218 FETDAASFHEAYFDILNFYIN 238
D +IL+FY N
Sbjct: 213 LSVDMNIVKNIAMEILDFYEN 233
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.323 0.138 0.405
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,697,407
Number of Sequences: 60738
Number of extensions: 776621
Number of successful extensions: 1826
Number of sequences better than 1.0e-05: 6
Number of HSP's better than 0.0 without gapping: 1
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 1818
Number of HSP's gapped (non-prelim): 6
length of query: 323
length of database: 30,389,216
effective HSP length: 106
effective length of query: 217
effective length of database: 23,950,988
effective search space: 5197364396
effective search space used: 5197364396
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)