ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIV2366 good O KOG0100 Posttranslational modification, protein turnover, chaperones Molecular chaperones GRP78/BiP/KAR2, HSP70 superfamily
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIV2366 805969 805577 -131
(131 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YJL034w [O] KOG0100 Molecular chaperones GRP78/BiP/KAR2 HSP70 su... 80 7e-16
At3g12580 [O] KOG0101 Molecular chaperones HSP70/HSC70 HSP70 sup... 55 3e-08
At5g02500 [O] KOG0101 Molecular chaperones HSP70/HSC70 HSP70 sup... 54 4e-08
At3g09440 [O] KOG0101 Molecular chaperones HSP70/HSC70 HSP70 sup... 54 4e-08
Hs18546205 [O] KOG0100 Molecular chaperones GRP78/BiP/KAR2 HSP70... 53 9e-08
Hs16507237 [O] KOG0100 Molecular chaperones GRP78/BiP/KAR2 HSP70... 53 9e-08
At5g02490 [O] KOG0101 Molecular chaperones HSP70/HSC70 HSP70 sup... 53 1e-07
CE08177 [O] KOG0100 Molecular chaperones GRP78/BiP/KAR2 HSP70 su... 52 2e-07
At1g16030 [O] KOG0101 Molecular chaperones HSP70/HSC70 HSP70 sup... 52 3e-07
SPCC1739.13 [O] KOG0101 Molecular chaperones HSP70/HSC70 HSP70 s... 51 5e-07
At5g28540 [O] KOG0100 Molecular chaperones GRP78/BiP/KAR2 HSP70 ... 49 1e-06
SPAC22A12.15c [O] KOG0100 Molecular chaperones GRP78/BiP/KAR2 HS... 49 2e-06
SPAC13G7.02c [O] KOG0101 Molecular chaperones HSP70/HSC70 HSP70 ... 49 2e-06
YAL005c [O] KOG0101 Molecular chaperones HSP70/HSC70 HSP70 super... 48 4e-06
Hs5729877 [O] KOG0101 Molecular chaperones HSP70/HSC70 HSP70 sup... 48 4e-06
Hs20550194 [O] KOG0101 Molecular chaperones HSP70/HSC70 HSP70 su... 47 5e-06
At5g42020 [O] KOG0100 Molecular chaperones GRP78/BiP/KAR2 HSP70 ... 47 5e-06
At1g09080 [O] KOG0100 Molecular chaperones GRP78/BiP/KAR2 HSP70 ... 47 9e-06
>YJL034w [O] KOG0100 Molecular chaperones GRP78/BiP/KAR2 HSP70 superfamily
Length = 682
Score = 80.1 bits (196), Expect = 7e-16
Identities = 36/70 (51%), Positives = 49/70 (69%)
Query: 36 NTFENFVHYVKNSVNGELAEIMDEDDKETVLDNVNESLEWLEDNSDVAEAEDFEEKMASF 95
N EN+ H +KN VNG+L E ++E+DKET+LD N+ LEWL+DN + A AEDF+EK S
Sbjct: 583 NKLENYAHSLKNQVNGDLGEKLEEEDKETLLDAANDVLEWLDDNFETAIAEDFDEKFESL 642
Query: 96 KESVEPILAK 105
+ PI +K
Sbjct: 643 SKVAYPITSK 652
>At3g12580 [O] KOG0101 Molecular chaperones HSP70/HSC70 HSP70 superfamily
Length = 650
Score = 54.7 bits (130), Expect = 3e-08
Identities = 25/77 (32%), Positives = 48/77 (61%), Gaps = 2/77 (2%)
Query: 36 NTFENFVHYVKNSVNGE-LAEIMDEDDKETVLDNVNESLEWLEDNSDVAEAEDFEEKMAS 94
N EN+ + ++N++ E +A +D DK+ + D +++++EWL+ N +AEA++FE+KM
Sbjct: 546 NALENYAYNMRNTIKDEKIASKLDAADKKKIEDAIDQAIEWLDGNQ-LAEADEFEDKMKE 604
Query: 95 FKESVEPILAKASASQG 111
+ PI+A+ G
Sbjct: 605 LESLCNPIIARMYQGAG 621
>At5g02500 [O] KOG0101 Molecular chaperones HSP70/HSC70 HSP70 superfamily
Length = 651
Score = 54.3 bits (129), Expect = 4e-08
Identities = 25/77 (32%), Positives = 47/77 (60%), Gaps = 2/77 (2%)
Query: 36 NTFENFVHYVKNSVNGE-LAEIMDEDDKETVLDNVNESLEWLEDNSDVAEAEDFEEKMAS 94
N EN+ + ++N++ E + E + DK+ + D++ ++++WLE N +AEA++FE+KM
Sbjct: 546 NALENYAYNMRNTIQDEKIGEKLPAADKKKIEDSIEQAIQWLEGNQ-LAEADEFEDKMKE 604
Query: 95 FKESVEPILAKASASQG 111
+ PI+AK G
Sbjct: 605 LESICNPIIAKMYQGAG 621
>At3g09440 [O] KOG0101 Molecular chaperones HSP70/HSC70 HSP70 superfamily
Length = 649
Score = 54.3 bits (129), Expect = 4e-08
Identities = 25/71 (35%), Positives = 45/71 (63%), Gaps = 2/71 (2%)
Query: 36 NTFENFVHYVKNSVNGE-LAEIMDEDDKETVLDNVNESLEWLEDNSDVAEAEDFEEKMAS 94
N EN+ + ++N++ E + E + DDK+ + D++ ++EWLE N +AE ++FE+KM
Sbjct: 546 NALENYAYNMRNTIRDEKIGEKLAGDDKKKIEDSIEAAIEWLEAN-QLAECDEFEDKMKE 604
Query: 95 FKESVEPILAK 105
+ PI+AK
Sbjct: 605 LESICNPIIAK 615
>Hs18546205 [O] KOG0100 Molecular chaperones GRP78/BiP/KAR2 HSP70 superfamily
Length = 573
Score = 53.1 bits (126), Expect = 9e-08
Identities = 28/78 (35%), Positives = 44/78 (55%), Gaps = 3/78 (3%)
Query: 36 NTFENFVHYVKNSVNGE--LAEIMDEDDKETVLDNVNESLEWLEDNSDVAEAEDFEEKMA 93
N E++ + +KN + + L + +DKET+ V E EWLE + D A+ EDF+ K
Sbjct: 482 NELESYAYSLKNQIGDKEKLGGKLSSEDKETMEKTVEEKTEWLESHQD-ADTEDFKAKKK 540
Query: 94 SFKESVEPILAKASASQG 111
+E V+PI++K S G
Sbjct: 541 ELEEIVQPIISKLYGSAG 558
>Hs16507237 [O] KOG0100 Molecular chaperones GRP78/BiP/KAR2 HSP70 superfamily
Length = 654
Score = 53.1 bits (126), Expect = 9e-08
Identities = 28/78 (35%), Positives = 45/78 (56%), Gaps = 3/78 (3%)
Query: 36 NTFENFVHYVKNSVNGE--LAEIMDEDDKETVLDNVNESLEWLEDNSDVAEAEDFEEKMA 93
N E++ + +KN + + L + +DKET+ V E +EWLE + D A+ EDF+ K
Sbjct: 563 NELESYAYSLKNQIGDKEKLGGKLSSEDKETMEKAVEEKIEWLESHQD-ADIEDFKAKKK 621
Query: 94 SFKESVEPILAKASASQG 111
+E V+PI++K S G
Sbjct: 622 ELEEIVQPIISKLYGSAG 639
>At5g02490 [O] KOG0101 Molecular chaperones HSP70/HSC70 HSP70 superfamily
Length = 653
Score = 52.8 bits (125), Expect = 1e-07
Identities = 24/71 (33%), Positives = 45/71 (62%), Gaps = 2/71 (2%)
Query: 36 NTFENFVHYVKNSVNGE-LAEIMDEDDKETVLDNVNESLEWLEDNSDVAEAEDFEEKMAS 94
N EN+ + ++N++ E + E + DK+ V D++ E+++WL+ N + EA++FE+KM
Sbjct: 546 NALENYAYNMRNTIRDEKIGEKLPAADKKKVEDSIEEAIQWLDGNQ-LGEADEFEDKMKE 604
Query: 95 FKESVEPILAK 105
+ PI+AK
Sbjct: 605 LESVCNPIIAK 615
>CE08177 [O] KOG0100 Molecular chaperones GRP78/BiP/KAR2 HSP70 superfamily
Length = 661
Score = 52.0 bits (123), Expect = 2e-07
Identities = 26/84 (30%), Positives = 50/84 (58%), Gaps = 3/84 (3%)
Query: 31 RAKLVNTFENFVHYVKNSVNGE--LAEIMDEDDKETVLDNVNESLEWLEDNSDVAEAEDF 88
+A+ N E++ + +KN + + L +DEDDK+T+ + V E++ WL N++ A AE+
Sbjct: 563 KAEARNELESYAYNLKNQIEDKEKLGGKLDEDDKKTIEEAVEEAISWLGSNAE-ASAEEL 621
Query: 89 EEKMASFKESVEPILAKASASQGS 112
+E+ + V+PI++K G+
Sbjct: 622 KEQKKDLESKVQPIVSKLYKDAGA 645
>At1g16030 [O] KOG0101 Molecular chaperones HSP70/HSC70 HSP70 superfamily
Length = 646
Score = 51.6 bits (122), Expect = 3e-07
Identities = 28/106 (26%), Positives = 63/106 (59%), Gaps = 7/106 (6%)
Query: 1 MTRVDCLRMISTEWSKKLKSMQLKMPNSRLRAKLVNTFENFVHYVKNSVNGE-LAEIMDE 59
+++ + +M+ K + Q+K ++ AK N+ EN+ + ++N++ E LA+ + +
Sbjct: 515 LSKEEIEKMVQDAEKYKAEDEQVK---KKVEAK--NSLENYAYNMRNTIKDEKLAQKLTQ 569
Query: 60 DDKETVLDNVNESLEWLEDNSDVAEAEDFEEKMASFKESVEPILAK 105
+DK+ + ++E++EW+E N +AE ++FE K+ + PI++K
Sbjct: 570 EDKQKIEKAIDETIEWIEGN-QLAEVDEFEYKLKELEGICNPIISK 614
>SPCC1739.13 [O] KOG0101 Molecular chaperones HSP70/HSC70 HSP70 superfamily
Length = 647
Score = 50.8 bits (120), Expect = 5e-07
Identities = 29/87 (33%), Positives = 52/87 (59%), Gaps = 4/87 (4%)
Query: 27 NSRLRAKLVNTFENFVHYVKNSVNG-ELAEIMDEDDKETVLDNVNESLEWLEDNSDVAEA 85
+ R++AK N E++ + ++NS++ L + +D DKETV V E++EWL+ N+ A+
Sbjct: 531 SGRIQAK--NHLESYAYSLRNSLDDPNLKDKVDASDKETVDKAVKETIEWLDSNTTAAK- 587
Query: 86 EDFEEKMASFKESVEPILAKASASQGS 112
++FE K + PI+AK + G+
Sbjct: 588 DEFEAKQKELESVANPIMAKIYQAGGA 614
>At5g28540 [O] KOG0100 Molecular chaperones GRP78/BiP/KAR2 HSP70 superfamily
Length = 669
Score = 49.3 bits (116), Expect = 1e-06
Identities = 25/78 (32%), Positives = 45/78 (57%), Gaps = 3/78 (3%)
Query: 36 NTFENFVHYVKNSVNGE--LAEIMDEDDKETVLDNVNESLEWLEDNSDVAEAEDFEEKMA 93
N E +V+ +KN VN + LA+ ++ D+KE + E+LEWL++N + +E E+++EK+
Sbjct: 571 NALETYVYNMKNQVNDKDKLADKLEGDEKEKIEAATKEALEWLDENQN-SEKEEYDEKLK 629
Query: 94 SFKESVEPILAKASASQG 111
+ PI+ G
Sbjct: 630 EVEAVCNPIITAVYQRSG 647
>SPAC22A12.15c [O] KOG0100 Molecular chaperones GRP78/BiP/KAR2 HSP70 superfamily
Length = 663
Score = 48.9 bits (115), Expect = 2e-06
Identities = 28/84 (33%), Positives = 45/84 (53%), Gaps = 4/84 (4%)
Query: 24 KMPNSRLRAKLVNTFENFVHYVKNSVNGE--LAEIMDEDDKETVLDNVNESLEWLEDNSD 81
K+ R+ A+ NT EN+ + +K + + L +D +DK+ VLD V + EWLE + +
Sbjct: 558 KILKERIEAR--NTLENYAYSLKGQFDDDEQLGGKVDPEDKQAVLDAVEDVAEWLEIHGE 615
Query: 82 VAEAEDFEEKMASFKESVEPILAK 105
A E+FE++ V PI K
Sbjct: 616 DASKEEFEDQRQKLDAVVHPITQK 639
>SPAC13G7.02c [O] KOG0101 Molecular chaperones HSP70/HSC70 HSP70 superfamily
Length = 644
Score = 48.5 bits (114), Expect = 2e-06
Identities = 27/86 (31%), Positives = 52/86 (60%), Gaps = 4/86 (4%)
Query: 28 SRLRAKLVNTFENFVHYVKNSVNG-ELAEIMDEDDKETVLDNVNESLEWLEDNSDVAEAE 86
SR++AK N E++ + ++NS++ L + +D DKE + V E++EWL+ N+ A+ +
Sbjct: 532 SRIQAK--NHLESYAYSLRNSLDDPNLKDKVDASDKEAIDKAVKETIEWLDHNTTAAK-D 588
Query: 87 DFEEKMASFKESVEPILAKASASQGS 112
++E+K + PI+AK + G+
Sbjct: 589 EYEDKQKELEGVANPIMAKIYQAGGA 614
>YAL005c [O] KOG0101 Molecular chaperones HSP70/HSC70 HSP70 superfamily
Length = 642
Score = 47.8 bits (112), Expect = 4e-06
Identities = 28/112 (25%), Positives = 64/112 (57%), Gaps = 7/112 (6%)
Query: 1 MTRVDCLRMISTEWSKKLKSMQLKMPNSRLRAKLVNTFENFVHYVKNSVNGELAEIMDED 60
+++ D +M++ ++K K K + R+ +K N E+ + +KN+++ E + +++
Sbjct: 507 LSKEDIEKMVAE--AEKFKEEDEK-ESQRIASK--NQLESIAYSLKNTIS-EAGDKLEQA 560
Query: 61 DKETVLDNVNESLEWLEDNSDVAEAEDFEEKMASFKESVEPILAKASASQGS 112
DK+TV E++ WL+ N+ A E+F++K+ ++ PI++K + G+
Sbjct: 561 DKDTVTKKAEETISWLDSNT-TASKEEFDDKLKELQDIANPIMSKLYQAGGA 611
>Hs5729877 [O] KOG0101 Molecular chaperones HSP70/HSC70 HSP70 superfamily
Length = 646
Score = 47.8 bits (112), Expect = 4e-06
Identities = 32/112 (28%), Positives = 58/112 (51%), Gaps = 7/112 (6%)
Query: 1 MTRVDCLRMISTEWSKKLKSMQLKMPNSRLRAKLVNTFENFVHYVKNSVNGE-LAEIMDE 59
+++ D RM+ ++K K+ K R + N+ E++ +K +V E L +++
Sbjct: 510 LSKEDIERMVQE--AEKYKAEDEKQ---RDKVSSKNSLESYAFNMKATVEDEKLQGKIND 564
Query: 60 DDKETVLDNVNESLEWLEDNSDVAEAEDFEEKMASFKESVEPILAKASASQG 111
+DK+ +LD NE + WL D + AE E+FE + ++ PI+ K S G
Sbjct: 565 EDKQKILDKCNEIINWL-DKNQTAEKEEFEHQQKELEKVCNPIITKLYQSAG 615
>Hs20550194 [O] KOG0101 Molecular chaperones HSP70/HSC70 HSP70 superfamily
Length = 198
Score = 47.4 bits (111), Expect = 5e-06
Identities = 32/112 (28%), Positives = 59/112 (52%), Gaps = 7/112 (6%)
Query: 1 MTRVDCLRMISTEWSKKLKSMQLKMPNSRLRAKLVNTFENFVHYVKNSVNGE-LAEIMDE 59
+++ D RM+ ++K K+ K R + N+ E++ +K +V E L +++
Sbjct: 62 LSKEDIERMVQE--AEKYKAEDEKQ---RDKVSSKNSLESYAFNMKATVEDEKLQGKIND 116
Query: 60 DDKETVLDNVNESLEWLEDNSDVAEAEDFEEKMASFKESVEPILAKASASQG 111
+DKE +LD NE + WL +N + A+ E+FE + ++ PI+ K S G
Sbjct: 117 EDKEKILDKCNEIIIWLNEN-ETAKKEEFEHQQKELEKVCNPIITKLYQSAG 167
>At5g42020 [O] KOG0100 Molecular chaperones GRP78/BiP/KAR2 HSP70 superfamily
Length = 668
Score = 47.4 bits (111), Expect = 5e-06
Identities = 24/78 (30%), Positives = 45/78 (56%), Gaps = 3/78 (3%)
Query: 36 NTFENFVHYVKNSVNGE--LAEIMDEDDKETVLDNVNESLEWLEDNSDVAEAEDFEEKMA 93
N E +V+ +KN V+ + LA+ ++ D+KE + E+LEWL++N + +E E+++EK+
Sbjct: 571 NALETYVYNMKNQVSDKDKLADKLEGDEKEKIEAATKEALEWLDENQN-SEKEEYDEKLK 629
Query: 94 SFKESVEPILAKASASQG 111
+ PI+ G
Sbjct: 630 EVEAVCNPIITAVYQRSG 647
>At1g09080 [O] KOG0100 Molecular chaperones GRP78/BiP/KAR2 HSP70 superfamily
Length = 678
Score = 46.6 bits (109), Expect = 9e-06
Identities = 24/70 (34%), Positives = 46/70 (65%), Gaps = 3/70 (4%)
Query: 36 NTFENFVHYVKNSV--NGELAEIMDEDDKETVLDNVNESLEWLEDNSDVAEAEDFEEKMA 93
N E +V+ +K++V +LA+ + ++DKE + + E+LEWLE+N + AE ED++EK+
Sbjct: 585 NKLETYVYNMKSTVADKEKLAKKISDEDKEKMEGVLKEALEWLEENVN-AEKEDYDEKLK 643
Query: 94 SFKESVEPIL 103
+ +P++
Sbjct: 644 EVELVCDPVI 653
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.309 0.124 0.331
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,224,654
Number of Sequences: 60738
Number of extensions: 233228
Number of successful extensions: 1351
Number of sequences better than 1.0e-05: 18
Number of HSP's better than 0.0 without gapping: 1
Number of HSP's successfully gapped in prelim test: 17
Number of HSP's that attempted gapping in prelim test: 1334
Number of HSP's gapped (non-prelim): 18
length of query: 131
length of database: 30,389,216
effective HSP length: 94
effective length of query: 37
effective length of database: 24,679,844
effective search space: 913154228
effective search space used: 913154228
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)