ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIV2394 good G KOG3893 Carbohydrate transport and metabolism Mannosyltransferase
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIV2394 816037 814832 -402
(402 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YJR013w [G] KOG3893 Mannosyltransferase 342 8e-94
SPBC13E7.05 [G] KOG3893 Mannosyltransferase 288 8e-78
Hs21553315 [G] KOG3893 Mannosyltransferase 249 7e-66
CE02103 [G] KOG3893 Mannosyltransferase 203 3e-52
7291318 [G] KOG3893 Mannosyltransferase 182 1e-45
>YJR013w [G] KOG3893 Mannosyltransferase
Length = 305
Score = 342 bits (876), Expect = 8e-94
Identities = 167/306 (54%), Positives = 220/306 (71%), Gaps = 4/306 (1%)
Query: 99 IKLLQGSCQLTKQLILASIWLLNPIVITISTRGNAESVLCFLIICALYFLKRDRLLISGL 158
+KLL + + LIL SIWLLNP+VITISTRGNAESVLC LI+ L+FL++ R ++G+
Sbjct: 1 MKLLNQAISRKRALILESIWLLNPMVITISTRGNAESVLCCLIMFTLFFLQKSRYTLAGI 60
Query: 159 FYGLSIHFKIYPIIYALPIGIYLLLSSHN---RNCIWRLFMIGISTLIGITAPTYFMYKL 215
YGLSIHFKIYPIIY +PI I++ + N R + L IG+STL + + MYK+
Sbjct: 61 LYGLSIHFKIYPIIYCIPIAIFIYYNKRNQGPRTQLTSLLNIGLSTLTTLLGCGWAMYKI 120
Query: 216 YGSEFIEHSYMYHLTRTDHRHNFSIWNLVLLLESAGIHLSQSIELSKLAFVPQLTLCAVL 275
YG EF++ +Y+YHL RTDHRHNFS+WN++L L+SA +S LS+ AFVPQL L V
Sbjct: 121 YGYEFLDQAYLYHLYRTDHRHNFSVWNMLLYLDSANKENGES-NLSRYAFVPQLLLVLVT 179
Query: 276 PYLLWKSQTFENLMNVLFVQTYAFVTFNKVCTSQYFIWYLVLSPFYFANTTITWRKGVVC 335
L W + TF+NL+ VLFVQT+AFVT+NKVCTSQYF+WYL+ PFY + T I W+KG++
Sbjct: 180 GCLEWWNPTFDNLLRVLFVQTFAFVTYNKVCTSQYFVWYLIFLPFYLSRTHIGWKKGLLM 239
Query: 336 IFLWILSQAVWLSQAYLLEFKGQNVFFPNLFFGNIVFFLINVYLLGVFITDIKSRTSFQD 395
LW+ +Q +WLSQ Y LEF+G+NVF+P LF +++FF+ NV+LLG FITDIK T
Sbjct: 240 ATLWVGTQGIWLSQGYYLEFEGKNVFYPGLFIASVLFFVTNVWLLGQFITDIKIPTQPTV 299
Query: 396 NQHKKN 401
+ K N
Sbjct: 300 SNKKNN 305
>SPBC13E7.05 [G] KOG3893 Mannosyltransferase
Length = 815
Score = 288 bits (738), Expect = 8e-78
Identities = 155/380 (40%), Positives = 218/380 (56%), Gaps = 18/380 (4%)
Query: 16 RIGFFSYGIFQDSHFDVKYTDIDYFVFHDAAGYVNNGQSPYLRDTXXXXXXXXXXXXXXX 75
R+ +YGI+ D +K+TDIDYFVF DA+ YV+ G SPY+RDT
Sbjct: 446 RLVLLNYGIWHDRRSALKFTDIDYFVFSDASKYVSIGMSPYMRDTYRYTPMLAILLLPTQ 505
Query: 76 XXKWIHMGKVFFVLFDLITGVMIIKLLQGSCQLTKQLILASIWLLNPIVITISTRGNAES 135
+ GK F + DLI G ++IKLL + LI +S W+LNP V ISTRGN E+
Sbjct: 506 YG-FPSWGKYLFSISDLIAGWLMIKLLSRRISYKRSLIYSSFWILNPFVAIISTRGNCEA 564
Query: 136 VLCFLIICALYFLKRDRLLISGLFYGLSIHFKIYPIIYALPIGIYLLLSSHNRNCIWRLF 195
+L L I LY +++ + ++ L G S+HFKIYP +Y + +Y + +
Sbjct: 565 ILGILSIALLYLIEKKSVWLASLILGFSVHFKIYPFMYGIAFLVYFSKPKKGSTFMEKFL 624
Query: 196 M--------IGISTLIGITAPTYFMYKLYGSEFIEHSYMYHLTRTDHRHNFSIWNLVLLL 247
I + +L T MY LYGS F+EH+Y+YH RTDHRHNFS+ +L L
Sbjct: 625 SLLSINQLKIVVGSLFMFTICNLLMYYLYGSPFLEHTYLYHFGRTDHRHNFSLHHLNLYY 684
Query: 248 ESAGIHLSQSIELSKLAFVPQLTLCAVLPYLLWKSQTFENLMNVLFVQTYAFVTFNKVCT 307
ES+ + S+ AF+PQL+LC ++P + K +NL LF QT+AFVTFNKVCT
Sbjct: 685 ESSFGAKASSL----FAFLPQLSLCMLIPLVFGK----KNLPGTLFAQTFAFVTFNKVCT 736
Query: 308 SQYFIWYLVLSPFYFANTTITWRKGVVCIFLWILSQAVWLSQAYLLEFKGQNVFFPNLFF 367
SQYF+WYLV P N+ + +KG++C+ LWI+ Q +WL AY LE G++VF P L+
Sbjct: 737 SQYFMWYLVFLPLVLPNSKLLSKKGLICLSLWIIGQLLWLISAYNLEMLGKSVFIP-LWL 795
Query: 368 GNIVFFLINVYLLGVFITDI 387
++FF NVY L + + +
Sbjct: 796 SGLLFFFFNVYELKIILDSL 815
>Hs21553315 [G] KOG3893 Mannosyltransferase
Length = 423
Score = 249 bits (635), Expect = 7e-66
Identities = 144/394 (36%), Positives = 210/394 (52%), Gaps = 31/394 (7%)
Query: 16 RIGFFSYGIFQDSHFDVKYTDIDYFVFHDAAGYVNNGQSPYLRDTXXXXXXXXXXXXXXX 75
R+ YG+FQD V+YTDIDY VF DAA +V G+SPYLR T
Sbjct: 29 RVALVFYGVFQDRTLHVRYTDIDYQVFTDAARFVTEGRSPYLRATYRYTPLLGWLLTPNI 88
Query: 76 XXKWIHMGKVFFVLFDLITGVMIIKLLQGSCQLTKQLI-LASIWLLNPIVITISTRGNAE 134
+ GK F+ DL+T ++ +LL +Q WLLNP+ + +S+RGNA+
Sbjct: 89 YLSEL-FGKFLFISCDLLTAFLLYRLLLLKGLGRRQACGYCVFWLLNPLPMAVSSRGNAD 147
Query: 135 SVLCFLIICALYFLKRDRLLISGLFYGLSIHFKIYPIIYALPIGIYLLLSSHN------- 187
S++ L++ LY +K+ + + +FYG ++H KIYP+ Y LPI ++LL N
Sbjct: 148 SIVASLVLMVLYLIKKRLVACAAVFYGFAVHMKIYPVTYILPITLHLLPDRDNDKSLRQF 207
Query: 188 ----RNCIW----RLFMIGISTLIGITAPTYF-----MYKLYGSEFIEHSYMYHLTRTDH 234
+ C++ RL + + + T+F Y YG EF+EH+Y YHLTR D
Sbjct: 208 RYTFQACLYELLKRLCNRAVLLFVAVAGLTFFALSFGFYYEYGWEFLEHTYFYHLTRRDI 267
Query: 235 RHNFSIWNLVLLLESAGIHLSQSIELSKLAFVPQLTLCAVLPYLLWKSQTFENLMNVLFV 294
RHNFS + +L L + S L AF+PQL L + + + ++ F F+
Sbjct: 268 RHNFSPYFYMLYLTAES---KWSFSLGIAAFLPQLILLSAVSFAYYRDLVF-----CCFL 319
Query: 295 QTYAFVTFNKVCTSQYFIWYLVLSPFYFANTTITWRKGVVCIFLWILSQAVWLSQAYLLE 354
T FVTFNKVCTSQYF+WYL L P + W++ VV + LW + QA+WL+ AY+LE
Sbjct: 320 HTSIFVTFNKVCTSQYFLWYLCLLPLVMPLVRMPWKRAVVLLMLWFIGQAMWLAPAYVLE 379
Query: 355 FKGQNVFFPNLFFGNIVFFLINVYLLGVFITDIK 388
F+G+N F ++ + F LIN +L I+ K
Sbjct: 380 FQGKNTFL-FIWLAGLFFLLINCSILIQIISHYK 412
>CE02103 [G] KOG3893 Mannosyltransferase
Length = 417
Score = 203 bits (517), Expect = 3e-52
Identities = 124/387 (32%), Positives = 195/387 (50%), Gaps = 33/387 (8%)
Query: 16 RIGFFSYGIFQDSHFDVKYTDIDYFVFHDAAGYVNNGQSPYLRDTXXXXXXXXXXXXXXX 75
RI Y D F V +TDIDY VF DAA +V+NG SP+ D
Sbjct: 26 RIILVFYAHIHDYLFKVNFTDIDYHVFSDAAKHVSNGGSPF--DRATYRYTPALAWILLP 83
Query: 76 XXKWIHMGKVFFVLFDLITGVMIIKLLQGSCQLTKQ-----------LILASIWLLNPIV 124
+ GK+ F +FD++ ++ K+++ TK + + WL NP+
Sbjct: 84 VVHFPDFGKILFCIFDILVAILYFKIMEKDLNETKSETREEMKDDQTMNVVIYWLANPLT 143
Query: 125 ITISTRGNAESVLCFLIICALYFLKRDRLLISGLFYG-LSIHFKIYPIIYALPIGIYLLL 183
IS RGNAES++ +++ + L++ + L +G L+I KIYP+IY LP L
Sbjct: 144 AIISARGNAESIVAAVVLLNIVLLQKGYWKSAALVHGALAIQLKIYPLIY-LPSVFLSLS 202
Query: 184 SSHNRNCI----------WRLFMIGISTLIGITAPTYFMYKLYGSEFIEHSYMYHLTRTD 233
+ ++C+ W+ F + TL A F +++YG F++ +YH+ R D
Sbjct: 203 TIGEQSCVVNKFKSLVSNWKGFAYMLVTLTSFAAVVLFFFQIYGQLFLDEYLIYHVKRRD 262
Query: 234 HRHNFSIWNLVLLLESAGIHLSQSIELSKLAFVPQLTLCAVLPYLLWKSQTFENLMNVLF 293
HNFS + +L L A +SQ I L AF+PQ+ L + + +++L F
Sbjct: 263 LAHNFSPYFYLLYLYEANPTMSQIIGLG--AFIPQIVLIVFFAF-----KHYDDLPFCWF 315
Query: 294 VQTYAFVTFNKVCTSQYFIWYLVLSPFYFANTTITWRKGVVCIFLWILSQAVWLSQAYLL 353
+ T+AFVT+NKVCTSQYF+WY+VL P ++ + + + W +Q +WL AYL
Sbjct: 316 ITTFAFVTYNKVCTSQYFVWYIVLLPLLAHKIMMSRQLALSLMAAWFATQGIWLLAAYLF 375
Query: 354 EFKGQNVFFPNLFFGNIVFFLINVYLL 380
EF+G N FF +F + +F + N ++L
Sbjct: 376 EFQGWNTFF-LMFLASCLFLIANSFIL 401
>7291318 [G] KOG3893 Mannosyltransferase
Length = 466
Score = 182 bits (461), Expect = 1e-45
Identities = 137/422 (32%), Positives = 189/422 (44%), Gaps = 66/422 (15%)
Query: 16 RIGFFSYGIFQDSHFDVKYTDIDYFVFHDAAGYVNNGQSPYLRDTXXXXXXXXXXXXXXX 75
RI YG DS V YTDIDY V D A V G +P+ R T
Sbjct: 34 RIALICYGQLHDSQSAVPYTDIDYKVVTDGARQVLAGDTPFARHTYRYSPIMAYLQTFNI 93
Query: 76 XXK--WIHMGKVFFVLFDLITGVMIIKL----LQGSCQLTKQLIL--------------- 114
W GK+ + FDL+ +I +L ++ Q T Q +L
Sbjct: 94 LLHPAW---GKLLYATFDLLIATLIYRLVHMEIKSQYQKTVQHLLSKFNRPRDSDQSLDA 150
Query: 115 --------------ASIWLLNPIVITISTRGNAESVLCFLIICALYFLKRDR-------- 152
A WL NP+ ISTRG+ + F +I +Y L +
Sbjct: 151 LDERSHPENLARASACFWLYNPLTAVISTRGSGDCFSSFFVILTIYLLLKSEHNVTRSYW 210
Query: 153 -LLISGLFYGLSIHFKIYPIIYALPIGIYLLLSSHN------------RNCIWRLFMIGI 199
+ +GL +GL IH ++YP++++L YL LS+ R +L +I
Sbjct: 211 LIFGAGLAHGLVIHLRLYPLLFSL--AYYLSLSTRLTQTPLDFLCQILRPNKQQLCLIS- 267
Query: 200 STLIGITAPTYFMYKLYGSEFIEHSYMYHLTRTDHRHNFSIWNLVLLLESAGIHLSQSIE 259
TLI + A T+ Y +YG E+I +Y+YH R D RHNFS+ L+ L SA S
Sbjct: 268 GTLISLVAFTWTFYTMYGWEYIYEAYLYHFVRKDPRHNFSLQFLLQYLGSASSVAEPSAI 327
Query: 260 LSKLAFVPQLTLCAVLPYLLWKSQTFENLMNVLFVQTYAFVTFNKVCTSQYFIWYLVLSP 319
L L PQ L +L L Q + L +F + VT+N V TSQYFIWYL + P
Sbjct: 328 LKTLVLAPQFLL--ILYLSLSFGQFRQTLPFCIFAVAFVIVTYNSVVTSQYFIWYLAILP 385
Query: 320 FYFAN-TTITWRKGVVCIFLWILSQAVWLSQAYLLEFKGQNVFFPNLFFGNIVFFLINVY 378
N ++WR+ +FLW+L+QA+WL AYLLEF N F+ + VFF N Y
Sbjct: 386 LCLNNFKMLSWRRCFGLLFLWLLAQALWLLPAYLLEFHTWNTFY-WIGLQGAVFFATNGY 444
Query: 379 LL 380
+L
Sbjct: 445 IL 446
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.333 0.146 0.466
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,157,794
Number of Sequences: 60738
Number of extensions: 883218
Number of successful extensions: 2119
Number of sequences better than 1.0e-05: 5
Number of HSP's better than 0.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 2091
Number of HSP's gapped (non-prelim): 6
length of query: 402
length of database: 30,389,216
effective HSP length: 109
effective length of query: 293
effective length of database: 23,768,774
effective search space: 6964250782
effective search space used: 6964250782
T: 11
A: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (22.0 bits)