ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIV2421 good A KOG2600 RNA processing and modification U3 small nucleolar ribonucleoprotein (snoRNP) subunit - Mpp10p
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIV2421 824125 822302 -608
(608 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YJR002w [A] KOG2600 U3 small nucleolar ribonucleoprotein (snoRNP... 489 e-138
SPAC23C11.03 [A] KOG2600 U3 small nucleolar ribonucleoprotein (s... 220 6e-57
Hs17462242 [A] KOG2600 U3 small nucleolar ribonucleoprotein (sno... 170 7e-42
At5g66540 [A] KOG2600 U3 small nucleolar ribonucleoprotein (snoR... 156 1e-37
7297429 [A] KOG2600 U3 small nucleolar ribonucleoprotein (snoRNP... 155 2e-37
CE23019 [A] KOG2600 U3 small nucleolar ribonucleoprotein (snoRNP... 116 9e-26
>YJR002w [A] KOG2600 U3 small nucleolar ribonucleoprotein (snoRNP) subunit -
Mpp10p
Length = 593
Score = 489 bits (1260), Expect = e-138
Identities = 277/615 (45%), Positives = 372/615 (60%), Gaps = 29/615 (4%)
Query: 1 MSQFLEILKTNPVGLLSQDALESKEPLSAVKTYFDEVINLNKNNG-NSKTTLDEIVVDGL 59
MS+ +LK+N ++ +D + + VK Y D VIN KN K LDEI VDGL
Sbjct: 1 MSELFGVLKSNAGRIILKDPSATSKD---VKAYIDSVINTCKNGSITKKAELDEITVDGL 57
Query: 60 DANQVWWQSKIILDNVQGDIMEKIAELKVXXXXXXXXXXXXXXXXXXXVENSNEMSADXX 119
DANQVWWQ K++LD++ GD+++ I ELK E+ E +
Sbjct: 58 DANQVWWQVKLVLDSIDGDLIQGIQELKDVVTPSHNLSDGSTLNSSSGEESELEEAESVF 117
Query: 120 XXXXXXXXXXXXXXXXXXXXXXXXXQQFXXXXXXXXXXXXXXXXXXXXXXXPDDQFVEAQ 179
++ + + Q
Sbjct: 118 KEKQMLSADVSEIEEQSNDSLSENDEE------PSMDDEKTSAEAAREEFAEEKRISSGQ 171
Query: 180 ESPQAIEDKFGVNDQFFNLDEFNRQTLEAENRSQXXXXXXXXXXXVDYFADVPSE-EDEE 238
+ + D +G+ND+FF+L++FNR TL AE+ ++ +DYF D+PS+ E+EE
Sbjct: 172 DERHSSPDPYGINDKFFDLEKFNRDTLAAEDSNEASEGSEDED--IDYFQDMPSDDEEEE 229
Query: 239 ALYYDDFFDKPSN---KKSSQDRRPGPXXXXXXXXXXXXXXXXXXXXMEEAKLDLFADED 295
A+YY+DFFDKP+ KK S + P M++ KLDLFADE+
Sbjct: 230 AIYYEDFFDKPTKEPVKKHSDVKDP--------KEDEELDEEEHDSAMDKVKLDLFADEE 281
Query: 296 DDFQGSDE-ETAEQPLSTFERQQLELKRQIESLEKEAVAEKKWALKGEVKARDRPEDALL 354
D+ E +++ LS+FE+QQ+E+++QIE LE EAVAEKKW+LKGEVKA+DRPEDALL
Sbjct: 282 DEPNAEGVGEASDKNLSSFEKQQIEIRKQIEQLENEAVAEKKWSLKGEVKAKDRPEDALL 341
Query: 355 TEDLEFERTAKPVPVITAEVTETLENMIRRRIKEEDFNDLQRRVISDISGYNNKPRFELS 414
TE+LEF+RTAKPVPVIT+EVTE+LE+MIRRRI++ +F+DLQRR + DI+ + +P+FELS
Sbjct: 342 TEELEFDRTAKPVPVITSEVTESLEDMIRRRIQDSNFDDLQRRTLLDITRKSQRPQFELS 401
Query: 415 DVKSSKSLAEIYEDDFKGVTEDTEISEELQKSHDEISELYKDLVYKLDALSSAHFIPKPI 474
DVKSSKSLAEIYEDD+ +++ +SEELQK+H EISELY +LVYKLD LSS HF+PKP
Sbjct: 402 DVKSSKSLAEIYEDDYTRAEDESALSEELQKAHSEISELYANLVYKLDVLSSVHFVPKPA 461
Query: 475 KKDLEVRVQTAAISMEDAQPLTMSSGSTLAPQEIYKVGKSENSNEITLKNGVVMSRDELS 534
LE+RV+T ISMEDAQPL MS+ S+LAPQEIY VGK+E EI LKNGV MS++EL+
Sbjct: 462 STSLEIRVETPTISMEDAQPLYMSNASSLAPQEIYNVGKAEKDGEIRLKNGVAMSKEELT 521
Query: 535 REDKNXXXXXXXXXXXXXXXXXXEQPRKKSKTDDVLNTLTKSKNITVIDKKGAKTDVKGN 594
REDKN K+SK +DV++TL+K+KNITVI++KG K DV G
Sbjct: 522 REDKN---RLRRALKRKRSKANLPNVNKRSKRNDVVDTLSKAKNITVINQKGEKKDVSGK 578
Query: 595 IKKDNAS-GNINFKL 608
KK + + N KL
Sbjct: 579 TKKSRSGPDSTNIKL 593
>SPAC23C11.03 [A] KOG2600 U3 small nucleolar ribonucleoprotein (snoRNP) subunit -
Mpp10p
Length = 598
Score = 220 bits (560), Expect = 6e-57
Identities = 142/449 (31%), Positives = 219/449 (48%), Gaps = 39/449 (8%)
Query: 180 ESPQAIEDK---FGVNDQFFNLDEFNRQTLEAENRSQXXXXXXXXXXXVDYFAD----VP 232
E Q IE K FG+ND FF++D FN+QTL E + +D D +
Sbjct: 146 EEGQQIEQKKDAFGLNDGFFDIDNFNKQTLALEEEAVEEGVLGDEDDGIDLLMDPDENME 205
Query: 233 SEEDE------EALYYDDFFDKPS-------NKKSSQDRRPGPXX-------XXXXXXXX 272
EDE +++ Y+DFF + KK ++ +R
Sbjct: 206 DSEDESNGPQADSIMYEDFFGPKTAAGRRELKKKKAESKRKRTSKPDFKNDVQQNVIEEN 265
Query: 273 XXXXXXXXXXMEEAKLDLFADEDDDFQGSDEETAEQPLSTFERQQLELKRQIESLEKEAV 332
+ K DLFA +++D +D+ LS++ER + L +QI LE E V
Sbjct: 266 NESSDNEYATFDRVKKDLFASDEEDDVSADQ------LSSYERDKARLTQQIRELEAENV 319
Query: 333 AEKKWALKGEVKARDRPEDALLTEDLEFERTAKPVPVITAEVTETLENMIRRRIKEEDFN 392
A+K W + GE ++ RP ++LL DLEFE AKPVPV T E TETLE++I+ RI + F+
Sbjct: 320 AKKSWTMMGEATSKGRPSNSLLDVDLEFETGAKPVPVQTEETTETLEDLIKNRIISKTFD 379
Query: 393 DLQRRVISDISGYNNKPRFELSDVKSSKSLAEIYEDDF----KGVTEDTEISEELQKSHD 448
D+ +R ++ + FEL++ KS +SLAE YE++F T +E ++ +K H+
Sbjct: 380 DVPKRAPVAVTEFRPSELFELNENKSQRSLAEEYEEEFLKKSNADTYKSEADKKKEKEHE 439
Query: 449 EISELYKDLVYKLDALSSAHFIPKPIKKDLEVRVQTAAISMEDAQPLTMSSGSTLAPQEI 508
EI L+ ++ LD+L+S H++P P + +E+ ++MED QP S LAPQE+
Sbjct: 440 EIKALFSEVSRTLDSLASWHYVPPPPESTVEIVSNAPTLAMEDVQPTAASDTMALAPQEV 499
Query: 509 YKVGKSENSNEITLKNGVVMSRDELSREDKNXXXXXXXXXXXXXXXXXXEQPRKKSKTDD 568
YK E ++G+ +S E+ + K E+ R+ S T+
Sbjct: 500 YKPSNENREGETITRSGIAISSTEMDHQQKQARRRRVRRKHAEKRKQMAEK-RRNSGTEQ 558
Query: 569 VLNTLTKSKNITVIDKKGAKTDVKGNIKK 597
V+ L+KS N+ VI K G + V N K
Sbjct: 559 VVRQLSKS-NVEVIGKGGERKKVASNSNK 586
>Hs17462242 [A] KOG2600 U3 small nucleolar ribonucleoprotein (snoRNP) subunit -
Mpp10p
Length = 681
Score = 170 bits (430), Expect = 7e-42
Identities = 125/456 (27%), Positives = 201/456 (43%), Gaps = 56/456 (12%)
Query: 187 DKFGVNDQFFNLDEFNRQTLEAENRSQXXXXXXXXXXXVDYFADVPSEEDEEALY----- 241
+K V+D+FF L E E + +D+F D+ S+EDE L+
Sbjct: 196 EKSIVDDKFFKLSEMEAYLENIEKEEERKDDNDEEEEDIDFFEDIDSDEDEGGLFGSKKL 255
Query: 242 ----------YDDFFDKPSNKKSSQDRRPGPXXXXXXXXXXXXXXXXXXXXMEEAKLDLF 291
Y DFFD + + + E
Sbjct: 256 KSGKSSRNLKYKDFFDPVESDEDITNVHDDELDSNKEDDEIAEEEAEELSISE------- 308
Query: 292 ADEDDDFQGSDE------------------------------ETAEQPLSTFERQQLELK 321
DEDDD Q +++ + +++ S+FE++Q ++
Sbjct: 309 TDEDDDLQENEDNKQHKESLKRVTFALPDDAETEDTGVLNVKKNSDEVKSSFEKRQEKMN 368
Query: 322 RQIESLEKEAVAEKKWALKGEVKARDRPEDALLTEDLEFERTAKPVPVITAEVTETLENM 381
+I SLEKE + +K W L+GEV A+ RPE++LL E L F+ + PVIT E T LE++
Sbjct: 369 EKIASLEKELLEKKPWQLQGEVTAQKRPENSLLEETLHFDHAVRMAPVITEETTLQLEDI 428
Query: 382 IRRRIKEEDFNDLQRRVISDISGYNNKPRFELSDVKSSKSLAEIYEDDFKGVTEDTEISE 441
I++RI+++ ++D+ R+ Y K R L KS SLAEIYE ++ + + + +E
Sbjct: 429 IKQRIRDQAWDDVVRKEKPKEDAYEYKKRLTLDHEKSKLSLAEIYEQEYIKLNQQ-KTAE 487
Query: 442 ELQKSHDEISELYKDLVYKLDALSSAHFIPKPIKKDLEVRVQTAAISMEDAQPLTMSSGS 501
E H EI ++ L KLDALS+ HFIPKP +++V AI+ME+ P+++S +
Sbjct: 488 EENPEHVEIQKMMDSLFLKLDALSNFHFIPKPPVPEIKVVSNLPAITMEEVAPVSVSDAA 547
Query: 502 TLAPQEIYKVGKSENSNEITLKNGVVMSRDELSRE-DKNXXXXXXXXXXXXXXXXXXEQP 560
LAP+EI + K+ + K R+ ++ K +Q
Sbjct: 548 LLAPEEIKEKNKAGDIKTAAEKTATDKKRERRKKKYQKRMKIKEKEKRRKLLEKSSVDQA 607
Query: 561 RKKSKT--DDVLNTLTKSKNITVIDKKGAKTDVKGN 594
K SKT + L LTK+ + I +G +K +
Sbjct: 608 GKYSKTVASEKLKQLTKTGKASFIKDEGKDKALKSS 643
>At5g66540 [A] KOG2600 U3 small nucleolar ribonucleoprotein (snoRNP) subunit -
Mpp10p
Length = 524
Score = 156 bits (394), Expect = 1e-37
Identities = 117/374 (31%), Positives = 181/374 (48%), Gaps = 37/374 (9%)
Query: 172 DDQFVEAQESPQAIEDKFGVNDQFFN---LDEFNRQTLEAENRSQXXXXXXXXXXXVDYF 228
+++ E +E + D G+ D+FF L+EF + E
Sbjct: 150 EEEEEEEEEEEEKDGDNEGIEDKFFKIKELEEFLEEGEAEEYGIDHKNKKGVAQRKKQNL 209
Query: 229 ADVPSEEDEEALYYDDFFDKPSNKKSSQDRRPGPXXXXXXXXXXXXXXXXXXXXMEEAKL 288
+D EED++ D FD + + + G +E K+
Sbjct: 210 SDDEDEEDDDDEEEDVEFDAFAGGDDEETDKLGKARYDDFFGGK-----------KETKM 258
Query: 289 DLFADEDDDFQGSDEETAEQPLSTFERQQLELKRQIESLEKEAVAEKKWALKGEVKARDR 348
L D +D + E + LST ER +L+L+ +IE +EK + K W ++GE+ A R
Sbjct: 259 KL-KDLSEDEEAEIENKGNEKLSTHERARLKLQSKIEQMEKANLDPKHWTMQGEITAAKR 317
Query: 349 PEDALLTEDLEFERTAKPVPVITAEVTETLENMIRRRIKEEDFNDLQRRVISDISGYNNK 408
P ++ L DL+FE A+P PVIT EVT +LE++I+ RI E F+D+QR G +
Sbjct: 318 PMNSALEVDLDFEHNARPAPVITEEVTASLEDLIKSRIIEARFDDVQRAPRLPTKG--KR 375
Query: 409 PRFELSDVKSSKSLAEIYEDDF----KGVTEDTEISEELQKSHDEISELYKDLVYKLDAL 464
EL + KS K LAE+YE ++ T S+EL+K E S L+K L KLDAL
Sbjct: 376 EAKELDESKSKKGLAEVYEAEYFQKANPAFAPTTHSDELKK---EASMLFKKLCLKLDAL 432
Query: 465 SSAHFIPKPIKKDLEVRVQTAAISMEDAQPLTMSSGSTLAPQEIYKVGKSENSNEITLKN 524
S HF PKP+ +++ + +AI+ME+ P+ +S + LAP+EI+ GK
Sbjct: 433 SHFHFTPKPVIEEMSI-PNVSAIAMEEVAPVAVSDAAMLAPEEIFS-GK----------- 479
Query: 525 GVVMSRDELSREDK 538
G + EL++ED+
Sbjct: 480 GDIKDESELTQEDR 493
>7297429 [A] KOG2600 U3 small nucleolar ribonucleoprotein (snoRNP) subunit -
Mpp10p
Length = 662
Score = 155 bits (392), Expect = 2e-37
Identities = 127/473 (26%), Positives = 205/473 (42%), Gaps = 73/473 (15%)
Query: 191 VNDQFFNLDEFNR---QTLEAENRSQXXXXXXXXXXXVDYFAD-----VPSEEDEEA-LY 241
V+D FF L+E N Q E R +D+FA+ E+DEE +
Sbjct: 168 VDDTFFKLEEMNEFLEQEDAKEMRRLNSKKRVEQADDIDHFAEDFGLGEDEEDDEEGNVN 227
Query: 242 YDDFFD---------KPSNK----------------KSSQDRRPGPXXXXXXXXXXXXXX 276
Y DFFD K NK + +D P
Sbjct: 228 YADFFDMNEELTEHSKKINKGKQKDFFNENESENENEPDEDANPKEGDSDQSEGDEGDDE 287
Query: 277 XXXXXXMEEAKLDLFADE-----------DDDFQGSDEETAEQPL-----STFERQQLEL 320
+EA ++ E D D EE QP S+ E ++ L
Sbjct: 288 PENDQDPDEAASEIDESEFVAKSGIEPASDSDSDSEKEEEEPQPTEPPSQSSNEMREARL 347
Query: 321 KRQIESLEKEAVAEKKWALKGEVKARDRPEDALLTEDLEFERTAKPVPVITAEVTETLEN 380
++I E + EK W LKGEVKA +RP+++LL E L+F+ T +P IT E ++E+
Sbjct: 348 FQRIRDYEDIVLGEKPWQLKGEVKAANRPQNSLLEEILDFDSTTRPTAPITEEDNRSIED 407
Query: 381 MIRRRIKEEDFNDLQRRVISDISGYNNKPRFELSDVKSSKSLAEIYEDDFKGVTEDTEIS 440
+I++RI+++ ++D++R V + + + L KS +SL++IYE ++ E + +
Sbjct: 408 IIKQRIRDKAWDDVERTVRPVNTPQEYRKQLVLDQEKSKQSLSQIYEAQYQREMEKLDPN 467
Query: 441 EELQ-------KSHDEISELYKDLVYKLDALSSAHFIPKPIKKDLEVRVQTAAISMEDAQ 493
+ K H EI + L KLDALS+ HF PKP+ ++++ T A+ ME+
Sbjct: 468 RDADDKTGPEPKEHQEIKRAMRSLFLKLDALSNFHFTPKPVAPEIKIVTNTPAVHMEEVA 527
Query: 494 PLTMSSGSTLAPQEIYK------VGKSENSNEITLKNGVVMSRDELSREDKNXXXXXXXX 547
PL +S LAP+E+++ +GK+E T KN R+ ++ K
Sbjct: 528 PLAVSDAKLLAPEEVFRGPKHAPLGKTERDR--TDKN-----RERRKKKQKQRAIHSALE 580
Query: 548 XXXXXXXXXXEQPRKKSKTDDVLNTLTKSKNITVIDKKGAKTDVKGNIKKDNA 600
+ P KK +L T+TK++N + K A ++ +G +K A
Sbjct: 581 QRELQRAKEGKAPTKKEADAKLLKTITKNRN---VQKINASSNDQGALKSSKA 630
>CE23019 [A] KOG2600 U3 small nucleolar ribonucleoprotein (snoRNP) subunit -
Mpp10p
Length = 648
Score = 116 bits (291), Expect = 9e-26
Identities = 91/384 (23%), Positives = 173/384 (44%), Gaps = 38/384 (9%)
Query: 173 DQFVEAQESPQAIEDKFGVNDQFFNLDEFNRQTLEAENRSQXXXXXXXXXXXVDYFADVP 232
++ +A E P+ + V+DQFFNLDE + + +++ F D
Sbjct: 176 EEVEKATEQPKKFKKSI-VDDQFFNLDEMH----DFLQKTERAGGKKAAQDEEMMFEDED 230
Query: 233 SEEDEEALYYDDFFDKPSN-----------KKSSQD--RRPGPXXXXXXXXXXXXXXXXX 279
S + + Y+DFF KK +D R+ G
Sbjct: 231 SWDGKTDYTYEDFFGSRETVAETEKMNGEKKKIEKDKKRKAGDKADLSLDDGKNKKRVRF 290
Query: 280 XXXMEEAKLDLFADEDDDFQGSDEETAEQPL------------STFERQQLELKRQIESL 327
E + ++ +E +D +E ++P+ S F ++Q ++K +I L
Sbjct: 291 AMDEEPEEEEVEDEEQEDINDEEEPPEDEPVLLGADLEEPKEESAFAKRQSKMKERIAKL 350
Query: 328 EKEAVAEKKWALKGEVKARDRPEDALLTEDLEFERTAKPVPVITAEVTETLENMIRRRIK 387
E+E +A K W L GEV A R ++ LL + ++F+ AK P +T E T+ LE++I++RI+
Sbjct: 351 EEENLAPKSWELSGEVAADQRDQNTLLEKHVDFDHGAKRAPEVTEEFTDRLESLIKQRIR 410
Query: 388 EEDFNDLQRRVISDISGYNNKPRFELSDVKSSKSLAEIYEDDFKGVT----EDTEISEEL 443
++ ++D+ R + G + + + SLAE+YE +++ T + + +
Sbjct: 411 DKAWDDVIRVKKVEAKGAKFETEAIENQMNQKTSLAEVYEKEYQNSTGNSADGAAGATKP 470
Query: 444 QKSHDEISELYKDLVYKLDALSSAHFIPKPIKKDLEVRVQTAAISMEDAQPLTMSSGSTL 503
++H+ I DL +DAL+ + P +++++V AA+ +E+ + +
Sbjct: 471 NEAHEAIKSKMGDLFRLIDALTHFEYKPDQAREEVKVVSNMAALRVEEVGITASTEAQLM 530
Query: 504 APQEIYK----VGKSENSNEITLK 523
AP+EI K + KS++ + T K
Sbjct: 531 APEEISKKMKAIEKSKDERDATDK 554
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.308 0.129 0.342
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,720,197
Number of Sequences: 60738
Number of extensions: 1121529
Number of successful extensions: 4347
Number of sequences better than 1.0e-05: 6
Number of HSP's better than 0.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 4315
Number of HSP's gapped (non-prelim): 13
length of query: 608
length of database: 30,389,216
effective HSP length: 112
effective length of query: 496
effective length of database: 23,586,560
effective search space: 11698933760
effective search space used: 11698933760
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)