ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIV2467 good L KOG1979 Replication, recombination and repair DNA mismatch repair protein - MLH1 family
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIV2467 839640 841811 724
(724 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YMR167w [L] KOG1979 DNA mismatch repair protein - MLH1 family 768 0.0
Hs4557757 [L] KOG1979 DNA mismatch repair protein - MLH1 family 490 e-138
SPBC1703.04 [L] KOG1979 DNA mismatch repair protein - MLH1 family 462 e-130
7304079 [L] KOG1979 DNA mismatch repair protein - MLH1 family 454 e-127
At4g09140 [L] KOG1979 DNA mismatch repair protein - MLH1 family 386 e-107
CE18978 [L] KOG1979 DNA mismatch repair protein - MLH1 family 303 6e-82
ECU05g0300 [L] KOG1979 DNA mismatch repair protein - MLH1 family 189 2e-47
Hs4505913 [L] KOG1978 DNA mismatch repair protein - MLH2/PMS1/Pm... 159 1e-38
SPAC19G12.02c [L] KOG1978 DNA mismatch repair protein - MLH2/PMS... 157 7e-38
7303075 [L] KOG1978 DNA mismatch repair protein - MLH2/PMS1/Pms2... 149 1e-35
At4g02460 [L] KOG1978 DNA mismatch repair protein - MLH2/PMS1/Pm... 147 7e-35
YNL082w [L] KOG1978 DNA mismatch repair protein - MLH2/PMS1/Pms2... 144 5e-34
Hs4505911 [L] KOG1978 DNA mismatch repair protein - MLH2/PMS1/Pm... 127 5e-29
CE19915 [L] KOG1978 DNA mismatch repair protein - MLH2/PMS1/Pms2... 124 4e-28
Hs4885551 [L] KOG1978 DNA mismatch repair protein - MLH2/PMS1/Pm... 109 1e-23
At4g35520 [L] KOG1977 DNA mismatch repair protein - MLH3 family 103 9e-22
Hs7657337 [L] KOG1977 DNA mismatch repair protein - MLH3 family 103 1e-21
YPL164c [L] KOG1977 DNA mismatch repair protein - MLH3 family 102 2e-21
Hs22046611 [L] KOG1978 DNA mismatch repair protein - MLH2/PMS1/P... 100 8e-21
YLR035c [R] KOG0017 FOG: Transposon-encoded proteins with TYA re... 100 1e-20
Hs22046253 [L] KOG1978 DNA mismatch repair protein - MLH2/PMS1/P... 77 1e-13
Hs4885553 [L] KOG1978 DNA mismatch repair protein - MLH2/PMS1/Pm... 70 1e-11
ECU11g1260 [L] KOG1978 DNA mismatch repair protein - MLH2/PMS1/P... 64 1e-09
>YMR167w [L] KOG1979 DNA mismatch repair protein - MLH1 family
Length = 769
Score = 768 bits (1982), Expect = 0.0
Identities = 414/776 (53%), Positives = 544/776 (69%), Gaps = 59/776 (7%)
Query: 1 MSGRIKPLDVSVVNKIAAGEIVIAPVNALKEMMENSIDAKATMVDILVKDGGIKLLQITD 60
MS RIK LD SVVNKIAAGEI+I+PVNALKEMMENSIDA ATM+DILVK+GGIK+LQITD
Sbjct: 1 MSLRIKALDASVVNKIAAGEIIISPVNALKEMMENSIDANATMIDILVKEGGIKVLQITD 60
Query: 61 NGCGIDKDDLPILCERFTTSKLEVFEDLSKIETFGFRGEALASISHIARVTVTTKTEKDQ 120
NG GI+K DLPILCERFTTSKL+ FEDLS+I+T+GFRGEALASISH+ARVTVTTK ++D+
Sbjct: 61 NGSGINKADLPILCERFTTSKLQKFEDLSQIQTYGFRGEALASISHVARVTVTTKVKEDR 120
Query: 121 CAWKASFSEGKILGQPKPVAGKTGTIITVEDLFYNIPSRLKALRSPGEEFNKILDVIGRY 180
CAW+ S++EGK+L PKPVAGK GT I VEDLF+NIPSRL+ALRS +E++KILDV+GRY
Sbjct: 121 CAWRVSYAEGKMLESPKPVAGKDGTTILVEDLFFNIPSRLRALRSHNDEYSKILDVVGRY 180
Query: 181 SINNNNVGFSCKKFGDSKVALMIKADLSTKDRVRIVFGANVSTNLMELNIDITDDVQRNG 240
+I++ ++GFSCKKFGDS +L +K + +DR+R VF +V++NL+ +I +D+
Sbjct: 181 AIHSKDIGFSCKKFGDSNYSLSVKPSYTVQDRIRTVFNKSVASNLITFHISKVEDL---N 237
Query: 241 LLSASGFVTNLDFTNKKPIPPAFFINGRLVSCDPMRRSFYQIYSNFLPKGNKPFIYFSLT 300
L S G V NL+F +KK I P FFIN RLV+CD +RR+ +YSN+LPKGN+PFIY +
Sbjct: 238 LESVDGKVCNLNFISKKSISPIFFINNRLVTCDLLRRALNSVYSNYLPKGNRPFIYLGIV 297
Query: 301 IKPQNVDVNIHPTKREVRFLNEEEIIDRLAILLQDKLASIDTSRTFKTASSVSN------ 354
I P VDVN+HPTKREVRFL+++EII+++A L +L++IDTSRTFK +S +N
Sbjct: 298 IDPAAVDVNVHPTKREVRFLSQDEIIEKIANQLHAELSAIDTSRTFKASSISTNKPESLI 357
Query: 355 PY--------------QVQLIGSSNESQDSPSTNLKMKRQENKLVRIDSSQVKITNYLRS 400
P+ Q Q++ +S + +S K KRQENKLVRID+SQ KIT++L S
Sbjct: 358 PFNDTIESDRNRKSLRQAQVVENSYTTANSQLR--KAKRQENKLVRIDASQAKITSFLSS 415
Query: 401 TK---FEFGASKNKTKKMNIEKIA----------------------DDNDTTLQNDGMEI 435
++ FE ++K + + + ++ +DND Q +
Sbjct: 416 SQQFNFEGSSTKRQLSEPKVTNVSHSQEAEKLTLNESEQPRDANTINDNDLKDQPKKKQK 475
Query: 436 ENDIEASYGDETSTQHTTLRNNTYYIVPKQRVQVNLTSIKKLKQAVDEQSHSELTNIFAN 495
D + + + + Y VPK+RV VNLTSIKKL++ VD+ H ELT+IFAN
Sbjct: 476 LGDYKVPSIADDEKNALPISKDGYIRVPKERVNVNLTSIKKLREKVDDSIHRELTDIFAN 535
Query: 496 LTYVGIVDETRRLASIQCDLKLFLVDYGSICNELFYQIGLSDFSNFGKIMLFDEDETEAG 555
L YVG+VDE RRLA+IQ DLKLFL+DYGS+C ELFYQIGL+DF+NFGKI L + ++
Sbjct: 536 LNYVGVVDEERRLAAIQHDLKLFLIDYGSVCYELFYQIGLTDFANFGKINLQSTNVSD-D 594
Query: 556 FNITKILENIDTLRIETIQE-IIEKLTSMKEMMNEYFSIEIETNDGGWN---KARIKSIP 611
+ +L D L + +E II K+ M M+NEY+SIE+ NDG N ++KS+P
Sbjct: 595 IVLYNLLSEFDELNDDASKEKIISKIWDMSSMLNEYYSIEL-VNDGLDNDLKSVKLKSLP 653
Query: 612 LLLKDYNPPLSKLPFFLYRLGTQVNWEDEMECLDGILRQLALFYIPPIIEKIHEND---P 668
LLLK Y P L KLPFF+YRLG +V+WEDE ECLDGILR++AL YIP ++ K+ +D
Sbjct: 654 LLLKGYIPSLVKLPFFIYRLGKEVDWEDEQECLDGILREIALLYIPDMVPKVDTSDASLS 713
Query: 669 EHLSSTYAAEMNELTDTMDHVVFPVIKRRLLAPKILLKDVVEVANLPGLYKVFERC 724
E + + ++ ++HV+FP IKRR LAP+ +LKDVVE+ANLP LYKVFERC
Sbjct: 714 EDEKAQFINRKEHISSLLEHVLFPCIKRRFLAPRHILKDVVEIANLPDLYKVFERC 769
>Hs4557757 [L] KOG1979 DNA mismatch repair protein - MLH1 family
Length = 756
Score = 490 bits (1261), Expect = e-138
Identities = 289/779 (37%), Positives = 455/779 (58%), Gaps = 81/779 (10%)
Query: 1 MSGRIKPLDVSVVNKIAAGEIVIAPVNALKEMMENSIDAKATMVDILVKDGGIKLLQITD 60
++G I+ LD +VVN+IAAGE++ P NA+KEM+EN +DAK+T + ++VK+GG+KL+QI D
Sbjct: 4 VAGVIRRLDETVVNRIAAGEVIQRPANAIKEMIENCLDAKSTSIQVIVKEGGLKLIQIQD 63
Query: 61 NGCGIDKDDLPILCERFTTSKLEVFEDLSKIETFGFRGEALASISHIARVTVTTKTEKDQ 120
NG GI K+DL I+CERFTTSKL+ FEDL+ I T+GFRGEALASISH+A VT+TTKT +
Sbjct: 64 NGTGIRKEDLDIVCERFTTSKLQSFEDLASISTYGFRGEALASISHVAHVTITTKTADGK 123
Query: 121 CAWKASFSEGKILGQPKPVAGKTGTIITVEDLFYNIPSRLKALRSPGEEFNKILDVIGRY 180
CA++AS+S+GK+ PKP AG GT ITVEDLFYNI +R KAL++P EE+ KIL+V+GRY
Sbjct: 124 CAYRASYSDGKLKAPPKPCAGNQGTQITVEDLFYNIATRRKALKNPSEEYGKILEVVGRY 183
Query: 181 SINNNNVGFSCKKFGDSKVALMIKADLSTKDRVRIVFGANVSTNLMELNIDITDDVQRNG 240
S++N + FS KK G++ + + ST D +R +FG VS L+E+ + +
Sbjct: 184 SVHNAGISFSVKKQGETVADVRTLPNASTVDNIRSIFGNAVSRELIEIGCE-----DKTL 238
Query: 241 LLSASGFVTNLDFTNKKPIPPAFFINGRLVSCDPMRRSFYQIYSNFLPKGNKPFIYFSLT 300
+G+++N +++ KK I FIN RLV +R++ +Y+ +LPK PF+Y SL
Sbjct: 239 AFKMNGYISNANYSVKKCI-FLLFINHRLVESTSLRKAIETVYAAYLPKNTHPFLYLSLE 297
Query: 301 IKPQNVDVNIHPTKREVRFLNEEEIIDRLAILLQDKLASIDTSRTFKTAS---SVSNPYQ 357
I PQNVDVN+HPTK EV FL+EE I++R+ ++ KL ++SR + T + ++ P
Sbjct: 298 ISPQNVDVNVHPTKHEVHFLHEESILERVQQHIESKLLGSNSSRMYFTQTLLPGLAGP-S 356
Query: 358 VQLIGSSNESQDSPSTNLKMKRQENKLVRIDSSQVKITNYLR-----------------S 400
+++ S+ S ++ K +++VR DS + K+ +L+
Sbjct: 357 GEMVKSTTSLTSSSTSGSSDKVYAHQMVRTDSREQKLDAFLQPLSKPLSSQPQAIVTEDK 416
Query: 401 TKFEFGASKNKTKKM----NIEKIADDNDTTLQNDGMEIENDIEASYGDETSTQHTTLRN 456
T G ++ + ++M ++A N +L+ D + +++ G +S R
Sbjct: 417 TDISSGRARQQDEEMLELPAPAEVAAKNQ-SLEGDTTKGTSEMSEKRGPTSSNPRKRHRE 475
Query: 457 N--------------TYYIVPKQRVQVNLTSIKKLKQAVDEQSHSELTNIFANLTYVGIV 502
+ T P++R+ +NLTS+ L++ ++EQ H L + N ++VG V
Sbjct: 476 DSDVEMVEDDSRKEMTAACTPRRRI-INLTSVLSLQEEINEQGHEVLREMLHNHSFVGCV 534
Query: 503 DETRRLASIQCDLKLFLVDYGSICNELFYQIGLSDFSNFGKIMLFDE-----------DE 551
+ LA Q KL+L++ + ELFYQI + DF+NFG + L + D
Sbjct: 535 NPQWALA--QHQTKLYLLNTTKLSEELFYQILIYDFANFGVLRLSEPAPLFDLAMLALDS 592
Query: 552 TEAGFNITKILENIDTLRIETIQEIIEKLTSMKEMMNEYFSIEIETNDGGWNKARIKSIP 611
E+G+ D + + I+E L EM+ +YFS+EI+ + + +P
Sbjct: 593 PESGWT------EEDGPKEGLAEYIVEFLKKKAEMLADYFSLEID------EEGNLIGLP 640
Query: 612 LLLKDYNPPLSKLPFFLYRLGTQVNWEDEMECLDGILRQLALFYIPPIIEKIHENDPEHL 671
LL+ +Y PPL LP F+ RL T+VNW++E EC + + ++ A+FY I K + ++ L
Sbjct: 641 LLIDNYVPPLEGLPIFILRLATEVNWDEEKECFESLSKECAMFY---SIRKQYISEESTL 697
Query: 672 SSTYAAEMNELTD----TMDHVVFPVIKRRLLAPKILLKD--VVEVANLPGLYKVFERC 724
S + + + T++H+V+ ++ +L PK +D ++++ANLP LYKVFERC
Sbjct: 698 SGQQSEVPGSIPNSWKWTVEHIVYKALRSHILPPKHFTEDGNILQLANLPDLYKVFERC 756
>SPBC1703.04 [L] KOG1979 DNA mismatch repair protein - MLH1 family
Length = 684
Score = 462 bits (1189), Expect = e-130
Identities = 277/733 (37%), Positives = 426/733 (57%), Gaps = 68/733 (9%)
Query: 4 RIKPLDVSVVNKIAAGEIVIAPVNALKEMMENSIDAKATMVDILVKDGGIKLLQITDNGC 63
+I+PLD V+NKIAAGEI+ P NA+KE++ENS+DA +T +D+L+KDGG+KLLQITDNG
Sbjct: 8 KIRPLDQLVINKIAAGEIIERPENAIKELIENSLDAGSTSIDVLLKDGGLKLLQITDNGS 67
Query: 64 GIDKDDLPILCERFTTSKLEVFEDLSKIETFGFRGEALASISHIARVTVTTKTEKDQCAW 123
GI DDLP LC+RF+TSK++ F DL ++TFGFRGEALASISH+A+VTV TK D AW
Sbjct: 68 GIQYDDLPYLCQRFSTSKIDNFNDLQHLQTFGFRGEALASISHVAKVTVVTKLSSDIHAW 127
Query: 124 KASFSEGKIL-------GQPKPVAGKTGTIITVEDLFYNIPSRLKALRSPGEEFNKILDV 176
KA + +G + P+P AGK GT+IT EDLFYN+ SR AL++ EEF +I+ +
Sbjct: 128 KAFYVDGALAPISPGMSPAPQPCAGKQGTVITAEDLFYNVRSRKSALKNGSEEFRRIMIL 187
Query: 177 IGRYSINNNNVGFSCKKFGDSKVALMIKADLSTKDRVRIVFGANVSTNLMELNIDITDDV 236
+ +Y+I+N+ V F+CKK GD+ +L + + LS D++R ++G V+++L + ++ +
Sbjct: 188 VQKYAIHNDQVSFNCKKVGDTVASLSLSSRLSKADKIRHIYGPRVASHLRDFSLG--EGQ 245
Query: 237 QRNGLLSASGFVTNLDFTNKKPIPPAFFINGRLVSCDPMRRSFYQIYSNFLPKGNKPFIY 296
SA+GF++N DF +KK FIN RLV +R + + Y+ +L KG F+Y
Sbjct: 246 SSIVGFSANGFISNADFQDKKS-NLILFINNRLVESVELRHALEETYAKYLHKGASYFVY 304
Query: 297 FSLTIKPQNVDVNIHPTKREVRFLNEEEIIDRLAILLQDKLASIDTSRTFKTASSVSNPY 356
SL + P+ +DVN+HP+KR V FL ++EI + L + L DT R++ P
Sbjct: 305 LSLNMSPEQLDVNVHPSKRIVHFLYDQEIATSICDKLGEILERTDTERSY--------PL 356
Query: 357 QVQLIGSSNESQDSPSTNLKMKRQENKLVRIDSSQVKITNYLRSTKFEFGASKNKTKKMN 416
Q + SN S+ ++ EN LVR D + I + L S F +S N ++
Sbjct: 357 QAMIPSISNTKNAESSSQKAVRTYENYLVRTDPRERSIKSML-SDNFLQRSSNNYDNEI- 414
Query: 417 IEKIADDNDTTLQNDGMEIENDIEASYGDETSTQHTTLRNNTYYIVPKQRVQVNLTSIKK 476
IEK+ N NDI+ + T+ N+ ++L SIK
Sbjct: 415 IEKVDS------ANSNKNATNDIK-----DLQTEEIVEEGNS----------IDLESIKS 453
Query: 477 LKQAVDEQSHSELTNIFANLTYVGIVDETRRLASIQCDLKLFLVDYGSICNELFYQIGLS 536
L++ V H TNI YVG+V TRR+A++Q ++ L++VDYG + LFYQI L+
Sbjct: 454 LQKQVINSMHVLATNILTEHKYVGLVCPTRRIAAVQHNIGLYVVDYGKLSYHLFYQICLT 513
Query: 537 DFSNFGKIMLFDEDETEAGFNITKILE--NIDTLRIETIQEIIEKLTSMKEMMNEYFSIE 594
+F N+G+ +L E +I+ + E N D + E+ ++ L S ++M+ +YFSI
Sbjct: 514 EFGNYGEFVL------ETPLSISDLFEIVNGDEDKSES-EKFTRLLVSRRDMLKDYFSIS 566
Query: 595 IETNDGGWNKARIKSIPLLLKDYNPPLSKLPFFLYRLGTQ-VNWEDEMECLDGILRQLAL 653
+ GG + ++P+L Y+PP +LP + L + +W DE CL+GI++ +A
Sbjct: 567 V--TSGG----LLTAVPMLSPKYHPPFEQLPLLISSLTPKFFDWLDEKSCLNGIMKAIAK 620
Query: 654 FYIPPIIEKIHENDPEHLSSTYAAEMNELTDTMDHVVFPVIKRRLLAPKILLKD--VVEV 711
FY+ P+ E+D + + S L ++ +FP +RR++ PK + ++ + ++
Sbjct: 621 FYV-PLPLSYEESDVKSIRS--------LESCLEDYLFPEFRRRVICPKKVFEEKCIYQI 671
Query: 712 ANLPGLYKVFERC 724
+LP LY VFERC
Sbjct: 672 TSLPRLYNVFERC 684
>7304079 [L] KOG1979 DNA mismatch repair protein - MLH1 family
Length = 664
Score = 454 bits (1169), Expect = e-127
Identities = 281/737 (38%), Positives = 412/737 (55%), Gaps = 95/737 (12%)
Query: 3 GRIKPLDVSVVNKIAAGEIVIAPVNALKEMMENSIDAKATMVDILVKDGGIKLLQITDNG 62
G I+ LD VVN+IAAGEI+ P NALKE++ENS+DA++T + + VK GG+KLLQI DNG
Sbjct: 8 GVIRKLDEVVVNRIAAGEIIQRPANALKELLENSLDAQSTHIQVQVKAGGLKLLQIQDNG 67
Query: 63 CGIDKDDLPILCERFTTSKLEVFEDLSKIETFGFRGEALASISHIARVTVTTKTEKDQCA 122
GI ++DL I+CERFTTSKL FEDLS+I TFGFRGEALASISH+A +++ TKT K++C
Sbjct: 68 TGIRREDLAIVCERFTTSKLTRFEDLSQIATFGFRGEALASISHVAHLSIQTKTAKEKCG 127
Query: 123 WKASFSEGKILGQPKPVAGKTGTIITVEDLFYNIPSRLKALRSPGEEFNKILDVIGRYSI 182
+KA++++GK+ GQPKP AG GTII +EDLFYN+P R +ALRSP EEF ++ +V+ RY++
Sbjct: 128 YKATYADGKLQGQPKPCAGNQGTIICIEDLFYNMPQRRQALRSPAEEFQRLSEVLARYAV 187
Query: 183 NNNNVGFSCKKFGDSKVALMIKADLSTKDRVRIVFGANVSTNLMELNIDITDDVQRNGLL 242
+N VGF+ +K GD++ AL S + +RI++GA +S L+E + D+V +
Sbjct: 188 HNPRVGFTLRKQGDAQPALRTPVASSRSENIRIIYGAAISKELLEFSH--RDEVYK---F 242
Query: 243 SASGFVTNLDFTNKKPIPPAFFINGRLVSCDPMRRSFYQIYSNFLPKGNKPFIYFSLTIK 302
A +T ++++ KK FIN RLV +R S IY+ +LP+G+ PF+Y SLT+
Sbjct: 243 EAECLITQVNYSAKK-CQMLLFINQRLVESTALRTSVDSIYATYLPRGHHPFVYMSLTLP 301
Query: 303 PQNVDVNIHPTKREVRFLNEEEIIDRLAILLQDKLASIDTSRTFKTASSVSNPYQVQLIG 362
PQN+DVN+HPTK EV FL +EEI+D + ++ +L + +RTF Q++L G
Sbjct: 302 PQNLDVNVHPTKHEVHFLYQEEIVDSIKQQVEARLLGSNATRTFYK--------QLRLPG 353
Query: 363 SSNESQDSPSTNLKMKRQE---NKLVRIDSSQVKITNYLRS-TKFEFGASKNKTKKMNIE 418
+ D T L K Q ++VR DS++ K+ +L K + G S + ++
Sbjct: 354 AP----DLDETQLADKTQRIYPKEMVRTDSTEQKLDKFLAPLVKSDSGVSSSSSQ----- 404
Query: 419 KIADDNDTTLQNDGMEIENDIEASYGDETSTQHTTLRNNTYYIVPKQRVQVNLTSIKKLK 478
EAS E S + T + + +V L+S+ ++
Sbjct: 405 ---------------------EASRLPEESFRVTAAKKSR---------EVRLSSVLDMR 434
Query: 479 QAVDEQSHSELTNIFANLTYVGIVDETRRLASIQCDLKLFLVDYGSICNELFYQIGLSDF 538
+ V+ Q +L + NL YVG VDE R L Q + +L++ + S ELFYQ + +F
Sbjct: 435 KRVERQCSVQLRSTLKNLVYVGCVDERRAL--FQHETRLYMCNTRSFSEELFYQRMIYEF 492
Query: 539 SNFGKI-----------MLFDEDETEAGFNITKILENIDTLRIETIQEIIEKLTSMKEMM 587
N +I ++ + AG+ D + E + L +M
Sbjct: 493 QNCSEITISPPLPLKELLILSLESEAAGWTPE------DGDKAELADGAADILLKKAPIM 546
Query: 588 NEYFSIEIETNDGGWNKARIKSIPLLLKDYNPPLSKLPFFLYRLGTQVNWEDEMECLDGI 647
EYF + I + DG ++S+P LL + P ++ LP +L RL T+V+WE E C +
Sbjct: 547 REYFGLRI-SEDG-----MLESLPSLLHQHRPCVAHLPVYLLRLATEVDWEQETRCFETF 600
Query: 648 LRQLALFYIPPIIEKIHENDPEHLSSTYAAEMNELTDTMDHVVFPVIKRRLLAPKILLKD 707
R+ A FY L A TM+HV+FP K+ LL P +
Sbjct: 601 CRETARFYA-------------QLDWREGATAGFSRWTMEHVLFPAFKKYLLPPPRIKDQ 647
Query: 708 VVEVANLPGLYKVFERC 724
+ E+ NLP LYKVFERC
Sbjct: 648 IYELTNLPTLYKVFERC 664
>At4g09140 [L] KOG1979 DNA mismatch repair protein - MLH1 family
Length = 737
Score = 386 bits (992), Expect = e-107
Identities = 259/772 (33%), Positives = 404/772 (51%), Gaps = 113/772 (14%)
Query: 4 RIKPLDVSVVNKIAAGEIVIAPVNALKEMMENSIDAKATMVDILVKDGGIKLLQITDNGC 63
+I+ L+ SVVN+IAAGE++ PV+A+KE++ENS+DA ++ + ++VKDGG+KL+Q++D+G
Sbjct: 28 KIQRLEESVVNRIAAGEVIQRPVSAVKELVENSLDADSSSISVVVKDGGLKLIQVSDDGH 87
Query: 64 GIDKDDLPILCERFTTSKLEVFEDLSKIETFGFRGEALASISHIARVTVTTKTEKDQCAW 123
GI ++DLPILCER TTSKL FEDL + + GFRGEALAS++++A VTVTT T+ +
Sbjct: 88 GIRREDLPILCERHTTSKLTKFEDLFSLSSMGFRGEALASMTYVAHVTVTTITKGQIHGY 147
Query: 124 KASFSEGKILGQPKPVAGKTGTIITVEDLFYNIPSRLKALRSPGEEFNKILDVIGRYSIN 183
+ S+ +G + +PK A GT I VE+LFYN+ +R K L++ +++ KI+D++ R +I+
Sbjct: 148 RVSYRDGVMEHEPKACAAVKGTQIMVENLFYNMIARRKTLQNSADDYGKIVDLLSRMAIH 207
Query: 184 NNNVGFSCKKFGDSKVALMIKADLSTKDRVRIVFGANVSTNLMELNIDITDDVQRNGLLS 243
NNV FSC+K G K + S D +R V+G +V+ NLM++ + D
Sbjct: 208 YNNVSFSCRKHGAVKADVHSVVSPSRLDSIRSVYGVSVAKNLMKVEVSSCD--SSGCTFD 265
Query: 244 ASGFVTNLDFTNKKPIPPAFFINGRLVSCDPMRRSFYQIYSNFLPKGNKPFIYFSLTIKP 303
GF++N ++ KK I FIN RLV C ++R+ +Y+ LPK +KPF+Y S+ +
Sbjct: 266 MEGFISNSNYVAKKTI-LVLFINDRLVECSALKRAIEIVYAATLPKASKPFVYMSINLPR 324
Query: 304 QNVDVNIHPTKREVRFLNEEEIIDRLAILLQDKLASIDTSRTFKTASSVSNPYQVQLIGS 363
++VD+NIHPTK+EV LN+E II+ + ++ KL + + +RTF+ +V+ I S
Sbjct: 325 EHVDINIHPTKKEVSLLNQEIIIEMIQSEVEVKLRNANDTRTFQ-------EQKVEYIQS 377
Query: 364 SNESQDS-------PSTNLKMKRQENKLVRIDSSQVKITNYLRSTKFEFGASKNKTKKMN 416
+ SQ S PS K NK+VR DSS
Sbjct: 378 TLTSQKSDSPVSQKPSGQKTQKVPVNKMVRTDSSDP------------------------ 413
Query: 417 IEKIADDNDTTLQNDGMEIENDIEASYGDETSTQHTTLRNNTYYIVPKQRVQVNLTSIKK 476
A LQ + + + + +S + R N PK+ +L+S+++
Sbjct: 414 ----AGRLHAFLQPKPQSLPDKVSSLSVVRSSVRQ---RRN-----PKE--TADLSSVQE 459
Query: 477 LKQAVDEQSHSELTNIFANLTYVGIVDETRRLASIQCDLKLFLVDYGSICNELFYQIGLS 536
L VD H + N TYVG+ D+ A +Q + L+L + ++ EL YQ L
Sbjct: 460 LIAGVDSCCHPGMLETVRNCTYVGMADDV--FALVQYNTHLYLANVVNLSKELMYQQTLR 517
Query: 537 DFSNFGKIMLFD-------------EDETEAGFNITKILENIDTLRIETIQEIIEKLTSM 583
F++F I L D E++ + G N TK D L+ + E L
Sbjct: 518 RFAHFNAIQLSDPAPLSELILLALKEEDLDPG-NDTK-----DDLKERIAEMNTELLKEK 571
Query: 584 KEMMNEYFSIEIETNDGGWNKARIKSIPLLLKDYNPPLSKLPFFLYRLGTQVNWEDEMEC 643
EM+ EYFS+ I+++ A + +P++L Y P + ++P FL LG V WEDE C
Sbjct: 572 AEMLEEYFSVHIDSS------ANLSRLPVILDQYTPDMDRVPEFLLCLGNDVEWEDEKSC 625
Query: 644 LDGILRQLALFYI--PPII-----------EKIHENDPEHLSSTYAAEMNELTD------ 684
G+ + FY PP++ K E+ E +M + D
Sbjct: 626 FQGVSAAIGNFYAMHPPLLPNPSGDGIQFYSKRGESSQEKSDLEGNVDMEDNLDQDLLSD 685
Query: 685 ----------TMDHVVFPVIKRRLLAPKILLKD--VVEVANLPGLYKVFERC 724
++ HV+FP ++ L P + + V+VA+L LYK+FERC
Sbjct: 686 AENAWAQREWSIQHVLFPSMRLFLKPPASMASNGTFVKVASLEKLYKIFERC 737
>CE18978 [L] KOG1979 DNA mismatch repair protein - MLH1 family
Length = 779
Score = 303 bits (776), Expect = 6e-82
Identities = 225/785 (28%), Positives = 392/785 (49%), Gaps = 89/785 (11%)
Query: 1 MSGRIKPLDVSVVNKIAAGEIVIAPVNALKEMMENSIDAKATMVDILVKDGGIKLLQITD 60
+ G I+ L VVN++AAGE++ P NA+KE++ENS+DA AT + + +++GG+KLLQ++D
Sbjct: 21 LMGLIQRLPQDVVNRMAAGEVLARPCNAIKELVENSLDAGATEIMVNMQNGGLKLLQVSD 80
Query: 61 NGCGIDKDDLPILCERFTTSKLEVFEDLSKIETFGFRGEALASISHIARVTVTTKTEKDQ 120
NG GI+++D ++CERF TSKL+ FEDL ++T+GFRGEALAS+SH+A+V + +K +
Sbjct: 81 NGKGIEREDFALVCERFATSKLQKFEDLMHMKTYGFRGEALASLSHVAKVNIVSKRADAK 140
Query: 121 CAWKASFSEGKILGQPKPVAGKTGTIITVEDLFYNIPSRLKALRSPGEEFNKILDVIGRY 180
CA++A+F +GK+ KP AGK GT IT DLFYN+P+R + + GEE + D + R+
Sbjct: 141 CAYQANFLDGKMTADTKPAAGKNGTCITATDLFYNLPTRRNKMTTHGEEAKMVNDTLLRF 200
Query: 181 SINNNNVGFSCK--KFGDSKVALMIKADLSTKDRVRIVFGANVSTNLMELNID------- 231
+I+ +V F+ + + GD + K D + +D V + G +V+ ++ L+++
Sbjct: 201 AIHRPDVSFALRQNQAGDFRT----KGDGNFRDVVCNLLGRDVADTILPLSLNSTRLKFT 256
Query: 232 ITDDVQRNGLLSASGFVTNLDFTNKKPIPPAFFINGRLVSCDPMRRSFYQIYSNFLPKGN 291
T + + + SA+ + T++ + FINGR V CD ++ ++ + +
Sbjct: 257 FTGHISK-PIASATAAIAQNRKTSRSFF--SVFINGRSVRCDILKHPIDEVLG--ARQLH 311
Query: 292 KPFIYFSLTIKPQNVDVNIHPTKREVRFLNEEEIIDRLAILLQ----------------- 334
F L I +DVN+HPTK V FL +EEII+ + +
Sbjct: 312 AQFCALHLQIDETRIDVNVHPTKNSVIFLEKEEIIEEIRAYFEKVIGEIFGFEALDVEKP 371
Query: 335 -------DKLASIDTSRTFKTASSVSNPYQVQLIGSSNESQDSPST-NLKMKRQENKLVR 386
+ L I S++ K+ ++ P + E + SPS KR + VR
Sbjct: 372 EEEQPDIENLVMIPMSQSLKSIEAIRKP------DTKPEFKSSPSAWKSDKKRVDYMEVR 425
Query: 387 IDSSQVKITNYL---------RSTKFEFGAS---KNKTKKMNIEKIADDNDTTLQNDGME 434
D+ + KI ++ S FG S K + + + D D +
Sbjct: 426 TDAKERKIDEFVTRGGAVGPTTSNDDIFGGSGILKRARTEDSTGGEKEPEDLNTDFDDVS 485
Query: 435 IENDIEASYGDE-TSTQHTTLRNNTYYIVPKQRVQVNLTSIKKLKQAVDEQSHSELTNIF 493
+ + + + G +Q ++ + K + + SI+ L++ + S L +F
Sbjct: 486 MVSLVSTADGRRLNESQDLGEDDDVDFEYGKTHREFHFESIEVLRKEIIANSSQSLREMF 545
Query: 494 ANLTYVGIVDETRRLASIQCDLKLFLVDYGSICNELFYQIGLSDFSNFGKIMLFDEDETE 553
T+VG ++ + L IQ L+ +D+ ++ E FYQI + F N+G L ++E
Sbjct: 546 KTSTFVGSINVKQVL--IQFGTSLYHLDFSTVLREFFYQISVFSFGNYGSYRL--DEEPP 601
Query: 554 AGFNITKILENIDT-----LRIETIQEIIEKLTSMK------EMMNEYFSIEIETNDGGW 602
A I ++L + T E + + + K +++++YF+I+++ + G
Sbjct: 602 AIIEILELLGELSTREPNYAAFEVFANVENRFAAEKLLAEHADLLHDYFAIKLDQLENG- 660
Query: 603 NKARIKSIPLLLKDYNPPLSKLPFFLYRLGTQVNWEDEMECLDGILRQLA-LFYIPPIIE 661
+ I IP L+ + P L KLPF + L V+++DE I R + LF +
Sbjct: 661 -RLHITEIPSLVHYFVPQLEKLPFLIATLVLNVDYDDEQNTFRTICRAIGDLFTLDTNFI 719
Query: 662 KIHENDPEHLSSTYAAEMNELTDTMDHVVFPVIKRRLLAPKILLKDVV--EVANLPGLYK 719
+ + +S+ A L + V+ P++KR+ + P+ + V ++A+ LYK
Sbjct: 720 TLDKK----ISAFSATPWKTL---IKEVLMPLVKRKFIPPEHFKQAGVIRQLADSHDLYK 772
Query: 720 VFERC 724
VFERC
Sbjct: 773 VFERC 777
>ECU05g0300 [L] KOG1979 DNA mismatch repair protein - MLH1 family
Length = 563
Score = 189 bits (479), Expect = 2e-47
Identities = 112/344 (32%), Positives = 188/344 (54%), Gaps = 18/344 (5%)
Query: 5 IKPLDVSVVNKIAAGEIVIAPVNALKEMMENSIDAKATMVDILVKDGGIKLLQITDNGCG 64
IK L V+++I+AGE++ P N LKE +ENS+DA +T + I ++ G+ L + D+G G
Sbjct: 3 IKRLPSDVISRISAGEVITRPYNILKETIENSLDANSTHITIKMEQDGLTLT-VEDDGDG 61
Query: 65 IDKDDLPILCERFTTSKLEVFEDLSKIETFGFRGEALASISHIARVTVTTKTEKDQCAWK 124
I + D +LC+++ TSKL E+L + ++GFRGEAL+SIS AR+ V +K + + ++
Sbjct: 62 IHESDFELLCKQYCTSKLTKEEELFSLSSYGFRGEALSSISRCARIKVRSKRREGEIGYE 121
Query: 125 ASFSEGKILGQPKPVAGKTGTIITVEDLFYNIPSRLKALRSPGEEFNKILDVIGRYSINN 184
A + + +++ K V K GTI+ ++++FYN R K EE +++ ++G YS+ N
Sbjct: 122 AVYRDTEMI-TIKGVGMKDGTIVEIKNIFYNNKVREKHFSKKREEIREMMWLVGMYSVFN 180
Query: 185 NNVGFSCKKFGDSKVALMIKADL-------STKDRVRIVFGANVSTNLMELNIDITDDVQ 237
+ + F F K+ + K+ + S +DRV+ G + + D +
Sbjct: 181 SRISFEL--FYGEKLQELPKSRVCVGEDGYSNEDRVKRKVGMLNELYKADGKLLFVSDKE 238
Query: 238 RNGLLSASGFVTNLDFTNKKPIPPAFFINGRLVSCDPMRRSFYQIYSNFLPKGNKPFIYF 297
+ S F F+NGRLV M+ S +++Y + LP +P IY
Sbjct: 239 YLVIFSTQQFCLRKGML-------VLFVNGRLVVSQEMKESLFKVYKDILPPQKQPLIYL 291
Query: 298 SLTIKPQNVDVNIHPTKREVRFLNEEEIIDRLAILLQDKLASID 341
L ++ VDVN+HP+KREV F NEE + RL + ++L+ +D
Sbjct: 292 ELYVEKSMVDVNVHPSKREVLFSNEESMTQRLCKCIAERLSKLD 335
>Hs4505913 [L] KOG1978 DNA mismatch repair protein - MLH2/PMS1/Pms2 family
Length = 862
Score = 159 bits (403), Expect = 1e-38
Identities = 107/357 (29%), Positives = 192/357 (52%), Gaps = 25/357 (7%)
Query: 5 IKPLDVSVVNKIAAGEIVIAPVNALKEMMENSIDAKATMVDILVKDGGIKLLQITDNGCG 64
IKP+D V++I +G++V++ A+KE++ENS+DA AT +D+ +KD G+ L++++DNGCG
Sbjct: 15 IKPIDRKSVHQICSGQVVLSLSTAVKELVENSLDAGATNIDLKLKDYGVDLIEVSDNGCG 74
Query: 65 IDKDDLPILCERFTTSKLEVFEDLSKIETFGFRGEALASISHIARVTVTTKTEKDQCAWK 124
+++++ L + TSK++ F DL+++ETFGFRGEAL+S+ ++ VT++T + +
Sbjct: 75 VEEENFEGLTLKHHTSKIQEFADLTQVETFGFRGEALSSLCALSDVTISTCHASAKVGTR 134
Query: 125 ASFSEGKILGQPKPVAGKTGTIITVEDLFYNIPSRLKAL-RSPGEEFNKILDVIGRYSIN 183
F + Q P GT ++V+ LF +P R K R+ +E+ K++ V+ Y I
Sbjct: 135 LMFDHNGKIIQKTPYPRPRGTTVSVQQLFSTLPVRHKEFQRNIKKEYAKMVQVLHAYCII 194
Query: 184 NNNVGFSCKK---FGDSKVALMIKADLSTKDRVRIVFGANVSTNLME-LNIDITDDVQRN 239
+ + SC G + + S K+ + VFG +L+ + + +D V
Sbjct: 195 SAGIRVSCTNQLGQGKRQPVVCTGGSPSIKENIGSVFGQKQLQSLIPFVQLPPSDSVCEE 254
Query: 240 GLLSASGFVTNLDFTN------------KKPIPPAFFINGRLVSCDPMR--RSFYQIYSN 285
LS S + NL + + FFIN R CDP + R ++Y +
Sbjct: 255 YGLSCSDALHNLFYISGFISQCTHGVGRSSTDRQFFFINRR--PCDPAKVCRLVNEVY-H 311
Query: 286 FLPKGNKPFIYFSLTIKPQNVDVNIHPTKREVRFLNEEEIIDRLAILLQDKLASIDT 342
+ PF+ ++++ + VD+N+ P KR++ L EE+++ LA+L + D+
Sbjct: 312 MYNRHQYPFVVLNISVDSECVDINVTPDKRQI-LLQEEKLL--LAVLKTSLIGMFDS 365
>SPAC19G12.02c [L] KOG1978 DNA mismatch repair protein - MLH2/PMS1/Pms2 family
Length = 794
Score = 157 bits (396), Expect = 7e-38
Identities = 109/370 (29%), Positives = 193/370 (51%), Gaps = 16/370 (4%)
Query: 5 IKPLDVSVVNKIAAGEIVIAPVNALKEMMENSIDAKATMVDILVKDGGIKLLQITDNGCG 64
+KP+D + V+KI +G+++ +A+KE++ENS+D+ AT ++I K+ GI +++ DNG G
Sbjct: 4 VKPIDANTVHKICSGQVITDVASAVKELVENSLDSGATTIEIRFKNYGINSIEVVDNGSG 63
Query: 65 IDKDDLPILCERFTTSKLEVFEDLSKIETFGFRGEALASISHIARVTVTTKTEKD-QCAW 123
ID D + ++ TSK+ FEDL ++TFGFRGEAL+S+ + +V ++T T+ +
Sbjct: 64 IDAGDYESIGKKHFTSKITDFEDLEALQTFGFRGEALSSLCAVGQVIISTATQNEAPKGV 123
Query: 124 KASFSEGKILGQPKPVAGKTGTIITVEDLFYNIPSRLKAL-RSPGEEFNKILDVIGRYSI 182
+ + L + + GT + V DLF +P R K L ++ EF+K + ++ Y+
Sbjct: 124 QLNLDHEGSLKDKLTIPFQRGTSVMVNDLFCTLPVRRKLLEKNYKREFSKAISLLQAYAT 183
Query: 183 NNNNVGFSCKKFGDSKVALMIKADLSTKD---RVRIVFGANVSTNLMELNIDITDDVQRN 239
+ N F + L+ + S KD + VFG VS++L+ N I +
Sbjct: 184 ISTNKRFMVYHQTKNSGKLLQLSTNSNKDMKLNIMNVFGTKVSSSLIPWNDGIIE----- 238
Query: 240 GLLSASGFVTNLDFTNKKPIPPAFFINGRLVSCDPMRRSFYQIYSNFLPKGNKPFIYFSL 299
G +S V + +N++ + FIN RLV+ + R +++ + PF +L
Sbjct: 239 GYISRP-HVGSTRASNERQM---LFINRRLVNLPKIARVIQEVFKPY-SMAQSPFFAINL 293
Query: 300 TIKPQNVDVNIHPTKREVRFLNEEEIIDRLAILLQDKLASIDTSRTFKTASSVSNPYQVQ 359
I +D+N+ P K+ V E+ II+ + LQ+ S + + + S+ + Y Q
Sbjct: 294 RITNGTIDINVSPDKKSVFLSEEDSIIEFIKNSLQNLCESCGHAISCSRSQSIFS-YSSQ 352
Query: 360 LIGSSNESQD 369
+ SS +S D
Sbjct: 353 IPDSSGDSTD 362
>7303075 [L] KOG1978 DNA mismatch repair protein - MLH2/PMS1/Pms2 family
Length = 899
Score = 149 bits (377), Expect = 1e-35
Identities = 106/392 (27%), Positives = 189/392 (48%), Gaps = 42/392 (10%)
Query: 1 MSGRIKPLDVSVVNKIAAGEIVIAPVNALKEMMENSIDAKATMVDILVKDGGIKLLQITD 60
+SG+IK + V+KI +G++V++ A+KE++ENSIDA AT+V+I +KD G++ ++++D
Sbjct: 23 LSGQIKAIGKDTVHKICSGQVVLSLAVAVKELVENSIDAGATLVEIKLKDQGLQSVEVSD 82
Query: 61 NGCGIDKDDLPILCERFTTSKLEVFEDLSKIETFGFRGEALASISHIARVTVTTKTEKDQ 120
NG G+++ +L + ++ TSK+ F DL +ETFGFRGEAL+S+ ++ + + T+ +
Sbjct: 83 NGSGVEEMNLEGMTAKYHTSKIREFVDLLGVETFGFRGEALSSLCALSDMVIQTRHKSTD 142
Query: 121 CAWKASFSEGKILGQPKPVAGKTGTIITVEDLFYNIPSRLKAL-RSPGEEFNKILDVIGR 179
K + + P A GT + + +LF +P R + R+ +EF K+ ++
Sbjct: 143 VGVKVELDHEGRIKKRSPCARGVGTTVLLANLFSTLPVRRRDFTRNIKKEFTKMCQILQA 202
Query: 180 YSINNNNVGFSCKKF---GDSKVALMIKADLSTKDRVRIVFGANVSTNLM---------- 226
Y + V C G + L D + +FGA + +L+
Sbjct: 203 YCLVTKGVRILCSNHTPKGAKTIVLQTHGDQEVMANISAIFGARQAADLVPLKSPFGQGQ 262
Query: 227 ----ELNIDI---------------TDDVQR--NGLLSASGFVTNLDFTNKKPIPPA--F 263
EL D+ T+DV+R GF+++ + F
Sbjct: 263 LTEAELRADLESGADLADTTSPQISTEDVERLNQADFQLEGFISSCRHGAGRSSRDRQFF 322
Query: 264 FINGRLVSCDP--MRRSFYQIYSNFLPKGNKPFIYFSLTIKPQNVDVNIHPTKREVRFLN 321
F+N R CDP + + ++Y + + +PFIY ++ +VDVN+ P KR++ N
Sbjct: 323 FVNSR--PCDPKNIAKVMNEVYHRYNVQ-QQPFIYLNIITARSDVDVNLTPDKRQLLINN 379
Query: 322 EEEIIDRLAILLQDKLASIDTSRTFKTASSVS 353
E ++ L L D + + + VS
Sbjct: 380 ERILLLALKKSLLDTFGQTPATFQMQNTTIVS 411
>At4g02460 [L] KOG1978 DNA mismatch repair protein - MLH2/PMS1/Pms2 family
Length = 779
Score = 147 bits (370), Expect = 7e-35
Identities = 102/354 (28%), Positives = 173/354 (48%), Gaps = 40/354 (11%)
Query: 5 IKPLDVSVVNKIAAGEIVIAPVNALKEMMENSIDAKATMVDILVKDGGIKLLQITDNGCG 64
I+P++ +V+++I +G++++ +A+KE++ENS+DA AT ++I ++D G Q+ DNGCG
Sbjct: 17 IRPINRNVIHRICSGQVILDLSSAVKELVENSLDAGATSIEINLRDYGEDYFQVIDNGCG 76
Query: 65 IDKDDLPI-----------LCERFTTSKLEVFEDLSKIETFGFRGEALASISHIARVTVT 113
I + + L + TSKLE F DL + T+GFRGEAL+S+ + +TV
Sbjct: 77 ISPTNFKVCVQILRRTFDVLALKHHTSKLEDFTDLLNLTTYGFRGEALSSLCALGNLTVE 136
Query: 114 TKTEKDQCAWKASFSEGKILGQPKPVAGKTGTIITVEDLFYNIPSRLKAL-RSPGEEFNK 172
T+T+ + A +F +L K A + GT +TV LF N+P R K R+ +E+ K
Sbjct: 137 TRTKNEPVATLLTFDHSGLLTAEKKTARQIGTTVTVRKLFSNLPVRSKEFKRNIRKEYGK 196
Query: 173 ILDVIGRYSINNNNVGFSCKKF---GDSKVALMIKADLSTKDRVRIVFGANVSTNLMELN 229
++ ++ Y++ V F C V L + S KD + VFG + T+L
Sbjct: 197 LVSLLNAYALIAKGVRFVCSNTTGKNPKSVVLNTQGRGSLKDNIITVFGISTFTSLQP-- 254
Query: 230 IDITDDVQRNGLLSASGFVTNLDFTNKKPIPPAFFINGRLVSCDPMRRSFYQIYSNFLPK 289
T + +++ FFINGR V + + ++Y + +
Sbjct: 255 ------------------GTGRNLADRQ----YFFINGRPVDMPKVSKLVNELYKDTSSR 292
Query: 290 GNKPFIYFSLTIKPQNVDVNIHPTKREVRFLNEEEIIDRLAILLQDKLASIDTS 343
P + D+N+ P KR+V F +E +I L L + +S + S
Sbjct: 293 -KYPVTILDFIVPGGACDLNVTPDKRKVFFSDETSVIGSLREGLNEIYSSSNAS 345
>YNL082w [L] KOG1978 DNA mismatch repair protein - MLH2/PMS1/Pms2 family
Length = 904
Score = 144 bits (363), Expect = 5e-34
Identities = 136/539 (25%), Positives = 239/539 (44%), Gaps = 63/539 (11%)
Query: 13 VNKIAAGEIVIAPVNALKEMMENSIDAKATMVDILVKDGGIKLLQITDNGCGIDKDDLPI 72
V++I +G+++ A+KE+++NSIDA A ++I+ KD G++ ++ +DNG GID +
Sbjct: 43 VHRITSGQVITDLTTAVKELVDNSIDANANQIEIIFKDYGLESIECSDNGDGIDPSNYEF 102
Query: 73 LCERFTTSKLEVFEDLSKIETFGFRGEALASISHIARVTVTTKTEKDQCAWKASFSEGKI 132
L + TSK+ F+D++K++T GFRGEAL+S+ IA+++V T T + A K +
Sbjct: 103 LALKHYTSKIAKFQDVAKVQTLGFRGEALSSLCGIAKLSVITTTSPPK-ADKLEYDMVGH 161
Query: 133 LGQPKPVAGKTGTIITVEDLFYNIPSRLKAL-RSPGEEFNKILDVIGRYSINNNNVGFSC 191
+ + GT + V LF+N+P R K ++ +F K L VI Y+I N + FS
Sbjct: 162 ITSKTTTSRNKGTTVLVSQLFHNLPVRQKEFSKTFKRQFTKCLTVIQGYAIINAAIKFSV 221
Query: 192 KKF---GDSKVALMIKADLSTKDRVRIVFGANVSTNLMELNIDI-------------TDD 235
G + L + S + + VFGA L E+++ + TDD
Sbjct: 222 WNITPKGKKNLILSTMRNSSMRKNISSVFGAGGMRGLEEVDLVLDLNPFKNRMLGKYTDD 281
Query: 236 ---------VQRNGLLSASGFVTNLDFTNKKPIPPAFFINGRLVSCDPMRRSFYQIYSNF 286
++ G +S + F + +++ I ++N R V + + ++Y F
Sbjct: 282 PDFLDLDYKIRVKGYISQNSFGCGRNSKDRQFI----YVNKRPVEYSTLLKCCNEVYKTF 337
Query: 287 LPKGNKPFIYFSLTIKPQNVDVNIHPTKREVRFLNEEEIIDRLAILLQDKLASIDTSRTF 346
P ++ +L + +DVN+ P KR + NE +ID L D + +
Sbjct: 338 -NNVQFPAVFLNLELPMSLIDVNVTPDKRVILLHNERAVIDIFKTTLSDYYNRQELALPK 396
Query: 347 KTASSVSNPYQVQLIGSSNESQDSPSTNLKMKRQENKLVRIDSSQVKITNYLRSTKFEFG 406
+ S Q +L E D ST + + R +S+Q ++ +T
Sbjct: 397 RMCSQSEQQAQKRL---KTEVFDDRSTTHESDNENYHTARSESNQSNHAHFNSTT----- 448
Query: 407 ASKNKTKKMNIEKIADDNDTTLQN-DGMEIENDIEASYGDETSTQHTTLRNNTYYIVPKQ 465
+K+ + + D N T + + G E E +++S + T +
Sbjct: 449 GVIDKSNGTELTSVMDGNYTNVTDVIGSECEVSVDSSVVLDEGNSSTPTK---------- 498
Query: 466 RVQVNLTSIKKLKQAVDEQSHSELT-NIFANLTYVGIV--DETRRLASIQCDLKLFLVD 521
L SIK D Q+ S+L N F+N + I D+ R L + + F +D
Sbjct: 499 ----KLPSIK-----TDSQNLSDLNLNNFSNPEFQNITSPDKARSLEKVVEEPVYFDID 548
>Hs4505911 [L] KOG1978 DNA mismatch repair protein - MLH2/PMS1/Pms2 family
Length = 932
Score = 127 bits (320), Expect = 5e-29
Identities = 103/365 (28%), Positives = 169/365 (46%), Gaps = 40/365 (10%)
Query: 5 IKPLDVSVVNKIAAGEIVIAPVNALKEMMENSIDAKATMVDILVKDGGIKLLQITDNGCG 64
+K L + V +++ +I+ + V+ +KE++ENS+DA AT VD+ +++ G +++ DNG G
Sbjct: 1 MKQLPAATVRLLSSSQIITSVVSVVKELIENSLDAGATSVDVKLENYGFDKIEVRDNGEG 60
Query: 65 IDKDDLPILCERFTTSKLEVFEDLSKIETFGFRGEALASISHIARVTVTTKTEKDQCAWK 124
I D P++ ++ TSK+ EDL + T+GFRGEAL SI IA V +TT+T D + +
Sbjct: 61 IKAVDAPVMAMKYYTSKINSHEDLENLTTYGFRGEALGSICCIAEVLITTRTAADNFSTQ 120
Query: 125 ASF-SEGKILGQPKPVAGKTGTIITVEDLFYNIPSR---LKALRSPGEEFNKILDVIGRY 180
G IL Q KP GT +T LF N+P R + +E KI D++ +
Sbjct: 121 YVLDGSGHILSQ-KPSHLGQGTTVTALRLFKNLPVRKQFYSTAKKCKDEIKKIQDLLMSF 179
Query: 181 SI----------NNNNVGFSCKKFGDSKVALMIKADLSTKDRVRIVFGANVSTNLMELNI 230
I +N V + + D K+ALM V G V N+
Sbjct: 180 GILKPDLRIVFVHNKAVIWQKSRVSDHKMALM------------SVLGTAVMNNMESFQY 227
Query: 231 DITDDVQRNGLLSASGFVTNLD----FTN-KKPIPPAFFINGRLVSCDPMRRSFYQIYSN 285
+ SGF+ D FT+ P FIN R V + + Y+
Sbjct: 228 H-----SEESQIYLSGFLPKCDADHSFTSLSTPERSFIFINSRPVHQKDILKLIRHHYNL 282
Query: 286 FLPKGNK---PFIYFSLTIKPQNVDVNIHPTKREVRFLNEEEIIDRLAILLQDKLASIDT 342
K + P + + + +VDVN+ P K +V N+E ++ L L+ + +
Sbjct: 283 KCLKESTRLYPVFFLKIDVPTADVDVNLTPDKSQVLLQNKESVLIALENLMTTCYGPLPS 342
Query: 343 SRTFK 347
+ +++
Sbjct: 343 TNSYE 347
>CE19915 [L] KOG1978 DNA mismatch repair protein - MLH2/PMS1/Pms2 family
Length = 805
Score = 124 bits (312), Expect = 4e-28
Identities = 88/348 (25%), Positives = 168/348 (47%), Gaps = 26/348 (7%)
Query: 4 RIKPLDVSVVNKIAAGEIVIAPVNALKEMMENSIDAKATMVDILVKDGGIKLLQITDNGC 63
+I+ + V ++ ++V++ +A++++++NSIDA +T++DI VK+ G + +++ DNG
Sbjct: 5 KIERISKEVAERLTTAQVVVSLSSAIRQLIDNSIDAGSTIIDIRVKNNGFESIEVQDNGS 64
Query: 64 GIDKDDLPILCERFTTSKLEVFEDLSKIETFGFRGEALASISHIARVTVTTKTEKDQCAW 123
GI+ + LC+ +TSKL F D K+ T GFRGEAL ++ ++ V++ T+ +
Sbjct: 65 GIEARNFDALCKPHSTSKLTQFSDFDKLATLGFRGEALNALCTVSSVSIFTRASDTEIGT 124
Query: 124 KASFSEGKILGQPKPVAGKTGTIITVEDLFYNIPSRLKAL-RSPGEEFNKILDVIGRYSI 182
+ ++ + + A + GT I V LF +P R K L RS EF K+L + +++
Sbjct: 125 RLTYDHSGNIICRQSAARELGTTIIVNKLFETLPVRRKELERSQKREFVKLLSTVQSFAL 184
Query: 183 NNNNVGFSCKKFGDSKVALMI---KADLSTKDRVRIVFG-------ANVSTNLMEL---- 228
++ C + K +I S +D V +FG + + + L+ +
Sbjct: 185 LCPHIKILCTNNINGKKTNLICTPGGTTSIQDVVANLFGIARKIENSKIGSGLIPIQQNQ 244
Query: 229 -NIDI-------TDDVQRNGLLSASGFVTNLDFTNKKPIPPAFF--INGRLVSCDPMRRS 278
+++I +++ L GFV++ + + F IN R V +
Sbjct: 245 PDVEIMTIHSVPMEEMHFFDLFKIRGFVSSCEHGCGRGTSDRQFVYINNRPVEYSRVCSV 304
Query: 279 FYQIYSNFLPKGNKPFIYFSLTIKPQNVDVNIHPTKREVRFLNEEEII 326
+Y F K P I + + P+ +DVN+ P K+ V E ++
Sbjct: 305 INDVYKQF-NKKQYPIIVLFIDVPPEKIDVNVTPDKKTVMLEKERHLL 351
>Hs4885551 [L] KOG1978 DNA mismatch repair protein - MLH2/PMS1/Pms2 family
Length = 389
Score = 109 bits (273), Expect = 1e-23
Identities = 60/156 (38%), Positives = 101/156 (64%), Gaps = 5/156 (3%)
Query: 5 IKPLDVSVVNKIAAGEIV--IAPVNALKEMMENSIDAKATMVDILVKDGGIKLLQITDNG 62
IKP+D V++I +G +V + P NA+KE++ENS+DA AT VD+ +KD G+ L++++ NG
Sbjct: 163 IKPIDRKSVHQICSGPVVPSLRP-NAVKELVENSLDAGATNVDLKLKDYGVDLIEVSGNG 221
Query: 63 CGIDKDDLPILCERFTTSKLEVFEDLSKIETFGFRGEALASISHIARVTVTTKTEKDQCA 122
CG+++++ + T K++ F DL+++ETFGFRGEAL+S+ ++ VT++T +
Sbjct: 222 CGVEEENFEGFTLKHHTCKIQEFADLTQVETFGFRGEALSSLCALSDVTISTCRVSAKVG 281
Query: 123 WKASFSE-GKILGQPKPVAGKTGTIITVEDLFYNIP 157
+ F GKI+ Q P G ++V+ LF +P
Sbjct: 282 TRLVFDHYGKII-QKTPYPRPRGMTVSVKQLFSTLP 316
>At4g35520 [L] KOG1977 DNA mismatch repair protein - MLH3 family
Length = 1151
Score = 103 bits (257), Expect = 9e-22
Identities = 80/247 (32%), Positives = 124/247 (49%), Gaps = 13/247 (5%)
Query: 5 IKPLDVSVVNKIAAGEIVIAPVNALKEMMENSIDAKATMVDILVKDGGIKL-LQITDNGC 63
IKPL V + + +G I+ ++E++ NS+DA AT V I V G + +++ D+G
Sbjct: 4 IKPLPEGVRHSMRSGIIMFDMARVVEELVFNSLDAGATKVSIFV--GVVSCSVKVVDDGS 61
Query: 64 GIDKDDLPILCERFTTSKLEVFEDLSKI-ETFGFRGEALASISHIARVTVTTKTEKDQCA 122
G+ +DDL +L ER+ TSK F ++ ETFGFRGEALASIS I+ + V TK
Sbjct: 62 GVSRDDLVLLGERYATSKFHDFTNVETASETFGFRGEALASISDISLLEVRTKAIGRPNG 121
Query: 123 WKASFSEGKILGQPKPVAGK-TGTIITVEDLFYNIPSRLKALR-SPGEEFNKILDVIGRY 180
++ K L K +GT +TV DLFY+ P R K ++ SP + I + R
Sbjct: 122 YRKVMKGSKCLHLGIDDDRKDSGTTVTVRDLFYSQPVRRKYMQSSPKKVLESIKKCVFRI 181
Query: 181 SINNNNVGFSCKKFGDSKVALMIKADLSTKDRVRIVFGANVSTNLMELNIDITDDVQRNG 240
++ ++NV FS + S + G +L ++N+ +G
Sbjct: 182 ALVHSNVSFSVLDIESDEELFQTNPSSSAFSLLMRDAGTEAVNSLCKVNV-------TDG 234
Query: 241 LLSASGF 247
+L+ SGF
Sbjct: 235 MLNVSGF 241
>Hs7657337 [L] KOG1977 DNA mismatch repair protein - MLH3 family
Length = 1429
Score = 103 bits (256), Expect = 1e-21
Identities = 88/338 (26%), Positives = 150/338 (44%), Gaps = 18/338 (5%)
Query: 5 IKPLDVSVVNKIAAGEIVIAPVNALKEMMENSIDAKATMVDILVKDGGIKLLQITDNGCG 64
IK L V V K+ +G + + ++E+ NSIDA+A V + V ++ Q+ DNG G
Sbjct: 2 IKCLSVEVQAKLRSGLAISSLGQCVEELALNSIDAEAKCVAVRVNMETFQV-QVIDNGFG 60
Query: 65 IDKDDLPILCERFTTSKLEVFEDLSKIETFGFRGEALASISHIA-RVTVTTKTEKDQCAW 123
+ DD+ + R+ TSK +DL +GFRGEALA+I+ +A V +++K + +
Sbjct: 61 MGSDDVEKVGNRYFTSKCHSVQDLENPRFYGFRGEALANIADMASAVEISSKKNRTMKTF 120
Query: 124 KASFSEGKILG--QPKPVAGKTGTIITVEDLFYNIPSRLKALRSPGEEFNKILDVIGRYS 181
F GK L + GT +TV +LFY +P R K + P EF K+ I S
Sbjct: 121 VKLFQSGKALKACEADVTRASAGTTVTVYNLFYQLPVRRKCM-DPRLEFEKVRQRIEALS 179
Query: 182 INNNNVGFSCKKFGDSKVALMIKADLSTKDRVRIVFGANVSTNLMELNIDITDDVQRNGL 241
+ + ++ FS + + L + R ++G S L E++ + +
Sbjct: 180 LMHPSISFSLRNDVSGSMVLQLPKTKDVCSRFCQIYGLGKSQKLREISFKYKEFELSGYI 239
Query: 242 LSASGFVTNLD--FTNKKPIPPA-------FFINGRLVSCDPMRRSFYQIYSNFLPKGNK 292
S + + N+ F NK+ + F + + C P + ++ L +
Sbjct: 240 SSEAHYNKNMQFLFVNKRLVLRTKLHKLIDFLLRKESIICKPKNGPTSRQMNSSLRHRST 299
Query: 293 PFIYFSLTIKPQ----NVDVNIHPTKREVRFLNEEEII 326
P +Y I Q DV + P K + F N + ++
Sbjct: 300 PELYGIYVINVQCQFCEYDVCMEPAKTLIEFQNWDTLL 337
>YPL164c [L] KOG1977 DNA mismatch repair protein - MLH3 family
Length = 715
Score = 102 bits (255), Expect = 2e-21
Identities = 102/454 (22%), Positives = 214/454 (46%), Gaps = 44/454 (9%)
Query: 1 MSGRIKPLDVSVVNKIAAGEIVIAPVNALKEMMENSIDAKATMVDILVKDGGIKLLQITD 60
MS I+ LD V ++ + ++ +A++E+++NS+DA AT +D+++ + + D
Sbjct: 1 MSQHIRKLDSDVSERLKSQACTVSLASAVREIVQNSVDAHATTIDVMIDLPNLSFA-VYD 59
Query: 61 NGCGIDKDDLPILCERFTTSKLEVFEDLSKIETFGFRGEALASISHIARVTVTTKTEKDQ 120
+G G+ + DL IL + TSK+ DL ++T+G+RG+AL SIS+++ + V +K +
Sbjct: 60 DGIGLTRSDLNILATQNYTSKIRKMNDLVTMKTYGYRGDALYSISNVSNLFVCSKKKDYN 119
Query: 121 CAWKASFSEGKILGQPKPV-------------AGKTGTIITVEDLFYNIPSRLKALRS-- 165
AW F ++ + K+GT++ VED+ YN+P R + L+
Sbjct: 120 SAWMRKFPSKSVMLSENTILPIDPFWKICPWSRTKSGTVVIVEDMLYNLPVRRRILKEEP 179
Query: 166 PGEEFNKI----LDVIGRYSINNNNVGFSCKKFGDSKVALMIK--ADLSTKDR-----VR 214
P + FN I L ++ + + + NV ++ K +++V K + TK + +R
Sbjct: 180 PFKTFNTIKADMLQILVMHPMISLNVQYTDKLRINTEVLFRSKNITEGLTKHQQMSQVLR 239
Query: 215 IVFGANVSTNLMELNIDITDDVQRNGLLSASGF-VTNLDF---TNKKPIPPAF--FINGR 268
VFGA + ++++ ++ Q G++S + +L F ++ AF +++
Sbjct: 240 NVFGAIIPPDMLKKVSLKFNEYQIEGIISKMPVGLKDLQFIYINGRRYADSAFQGYVDSL 299
Query: 269 LVSCDPMRRSFYQIYSNFLPKGNKPFIYFSLTIK-PQNVDVNIH-PTKREVRFLNEEEII 326
+ D + + + + K + F L ++ PQ +D + P K+ V+ I
Sbjct: 300 FQAQDFGEKGMSLLKTKSVGKPYRSHPVFILDVRCPQTIDDLLQDPAKKIVK----PSHI 355
Query: 327 DRLAILLQDKLASIDTSRTFKTASSVSNPYQVQLIGSSNESQDSPSTNLKMKRQENKLVR 386
+ L+ + S T + + T + +++ + S ++ P + +++ ++ N+++
Sbjct: 356 RTIEPLIVKTIRSFLTFQGYLTPDKSDSSFEI--VNCSQKTATLPDSRIQISKR-NQVLN 412
Query: 387 IDSSQVKITNYLRSTKFEFGASKNKTKKMNIEKI 420
+I +Y+ N T +N EKI
Sbjct: 413 SKMKIARINSYIGKPAVNGCRINNST--INYEKI 444
>Hs22046611 [L] KOG1978 DNA mismatch repair protein - MLH2/PMS1/Pms2 family
Length = 199
Score = 100 bits (249), Expect = 8e-21
Identities = 52/131 (39%), Positives = 87/131 (65%), Gaps = 2/131 (1%)
Query: 32 MMENSIDAKATMVDILVKDGGIKLLQITDNGCGIDKDDLPILCERFTTSKLEVFEDLSKI 91
M+ENS+DA AT +D+ +KD G+ L++++ NGCG+++++ L + TSK++ F DL+++
Sbjct: 1 MVENSLDAGATNIDLKLKDYGMDLIEVSGNGCGVEEENFEGLTLKHHTSKIQEFADLTRV 60
Query: 92 ETFGFRGEALASISHIARVTVTTKTEKDQCAWKASFS-EGKILGQPKPVAGKTGTIITVE 150
ETFGFRGEAL+S+ ++ VT++T + + F +GKI+ Q P GT ++V+
Sbjct: 61 ETFGFRGEALSSLCALSDVTISTCHVSAKVGTRLVFDHDGKII-QKTPYPHPRGTTVSVK 119
Query: 151 DLFYNIPSRLK 161
LF +P R K
Sbjct: 120 QLFSTLPVRHK 130
>YLR035c [R] KOG0017 FOG: Transposon-encoded proteins with TYA reverse
transcriptase integrase domains in various combinations
Length = 695
Score = 100 bits (248), Expect = 1e-20
Identities = 90/356 (25%), Positives = 162/356 (45%), Gaps = 40/356 (11%)
Query: 15 KIAAGEIVIAPVNALKEMMENSID--AKATMVDILVKDGGIKLLQITDNGCGIDKDDLPI 72
KI + + PV A++E+++NSID AK +D+ GG + + + D+G G+D D P
Sbjct: 13 KIVSSSFIYGPVAAVRELLDNSIDSGAKKVFIDVDSTTGGCEYISVKDDGSGVDIIDRPS 72
Query: 73 LCERFTTSKLEVFEDLSKIETFGFRGEALASISHIAR----VTVTTKTEKDQCA--WKAS 126
+C +TTSK+ D+S + T GFRGEAL +S++ + V TKT D W
Sbjct: 73 MCLEYTTSKMSSLGDISILTTLGFRGEALFLLSNLCNQKGSMQVETKTADDVIGEKWLVD 132
Query: 127 FSEGKILGQPKPVAGKTGTIITVEDLFYNIPSRLKALRS-PGEEFNKILDVIGRYSINNN 185
G G+ V+ GT + + L + +R + S P + F++++ +I YS+ +
Sbjct: 133 SKGGITNGKRYKVSCPVGTTVILRKLLGGLRARYLEISSRPRKTFDELIYLINHYSLIHR 192
Query: 186 NVGFSCKKFGDSKVALMIKADLSTKDRVRIVFGANVSTNLMELNIDITDDVQRNGLLSAS 245
N+ +F S V+L + K + + L + V N ++ +
Sbjct: 193 NI-----RFYFSLVSLQKNGAIERKQMQETLDPKISRARSLSLLARLKKPVPLNFIVEEN 247
Query: 246 GFV---TNLDFTNKKPIPPAFFINGR----------------LVSCDPMRRSFYQIYSNF 286
+ NLD + +P + IN + L + + + IY +F
Sbjct: 248 FVIDEKINLDLILPRMVPESDVINIKRRFKFLSVNERALSLNLETGKTISKLLSSIYRDF 307
Query: 287 LPKGNKPFIYF-SLTIKPQNVDVNIHPTKREVRFLNEE----EIIDRLAILLQDKL 337
P ++F +L + +DVNI P K +V + E +I ++L +LL++++
Sbjct: 308 --SLLDPMVWFINLNCDTKLLDVNIEPEKNDVMIKSFEVIFKKIENKLKLLLEERI 361
>Hs22046253 [L] KOG1978 DNA mismatch repair protein - MLH2/PMS1/Pms2 family
Length = 178
Score = 76.6 bits (187), Expect = 1e-13
Identities = 40/108 (37%), Positives = 69/108 (63%), Gaps = 2/108 (1%)
Query: 55 LLQITDNGCGIDKDDLPILCERFTTSKLEVFEDLSKIETFGFRGEALASISHIARVTVTT 114
L++++ NGCG+++++ L + TSK++ F DL+++ETFGFRGEAL+S+ ++ VT++T
Sbjct: 3 LIEVSGNGCGVEEENFKGLTLKHHTSKIQEFADLTRVETFGFRGEALSSLCALSDVTIST 62
Query: 115 KTEKDQCAWKASFS-EGKILGQPKPVAGKTGTIITVEDLFYNIPSRLK 161
+ + F +GKI+ Q P GT ++V+ LF +P R K
Sbjct: 63 CHVSAKVGTRLVFDHDGKII-QKTPYPHPRGTTVSVKQLFSTLPVRHK 109
>Hs4885553 [L] KOG1978 DNA mismatch repair protein - MLH2/PMS1/Pms2 family
Length = 264
Score = 70.1 bits (170), Expect = 1e-11
Identities = 28/65 (43%), Positives = 52/65 (79%)
Query: 5 IKPLDVSVVNKIAAGEIVIAPVNALKEMMENSIDAKATMVDILVKDGGIKLLQITDNGCG 64
IKP+D V++I +G +V++ A+KE++ENS+DA AT +D+ +KD G+ L++++DNGCG
Sbjct: 186 IKPIDRKSVHQICSGPVVLSLSTAVKELVENSLDAGATNIDLKLKDYGVDLIEVSDNGCG 245
Query: 65 IDKDD 69
+++++
Sbjct: 246 VEEEN 250
>ECU11g1260 [L] KOG1978 DNA mismatch repair protein - MLH2/PMS1/Pms2 family
Length = 630
Score = 63.5 bits (153), Expect = 1e-09
Identities = 93/374 (24%), Positives = 156/374 (40%), Gaps = 47/374 (12%)
Query: 5 IKPLDVSVVNKIAAGEIVIAPVNALKEMMENSIDAKATMVDILVKDGGIKLLQITDNGCG 64
I+ L V +I A V + +KE++EN+ID+ T + ILV D + + DNGCG
Sbjct: 2 IRKLPEDVGKRIRAQRSVQSIYIVVKELIENAIDSGCTWIRILVDDA----ITVEDNGCG 57
Query: 65 IDKDDLPILCERFTTSKLEV------FEDLSKIETFGFRGEALASISHIARVTVTTKTEK 118
I DL + TSK + + D + ++GFRG+AL+ ++ + + + +++E
Sbjct: 58 I--SDLDKVGVEGATSKESMAYYVLGYADRVEKFSYGFRGQALSCLAEVCDLEIISRSE- 114
Query: 119 DQCAWKASFSEGKILGQPKPVAGKTGTIITVEDLFYNIPSRLKALRSPG--EEFNKILDV 176
A + FS I A + GT + V +LF N P R + + G + KI +
Sbjct: 115 HSFALRKDFSTNAI----SKCARERGTTVHVRNLFKNCPLR-RPMADSGLKRDLGKICSL 169
Query: 177 IGRYSINNNNVGFSCKKFGDSKVALMIKADLSTKDRVRIVFGANVSTNLMELNIDITDDV 236
I Y N + F+ F KV L + VR F +N + + +
Sbjct: 170 IESYRC-ANKINFTL--FHKRKVLL----SCGGYETVREYFESNYPSFAGKCMEVCNGQM 222
Query: 237 QRNGLLSASGFVTNLDFTNKKPIPPAFFINGRLVSCDPMRRSFYQIYSNFLPKGNKPFIY 296
L L F+ ++PI +N +S + +Y P
Sbjct: 223 DLFMLPVCVKEPKQLMFSERRPISNRRILNA--------VKSEFGLYVEGSPT------- 267
Query: 297 FSLTIKPQNVDVNIHPTKREVRFLNEEEIIDRLAILLQDKLASIDTSRTFKTASSVSNPY 356
F L IK DVN+ K EV F +E I++ LL+ ++ +S + +S
Sbjct: 268 FVLVIKGYG-DVNVSADKSEVIFADEAGILN----LLRSEIGRFFSSEMYLNPASAVRRQ 322
Query: 357 QVQLIGSSNESQDS 370
+ + S+ +DS
Sbjct: 323 KSNVQERSDAGEDS 336
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.318 0.136 0.381
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 41,778,845
Number of Sequences: 60738
Number of extensions: 1814777
Number of successful extensions: 5531
Number of sequences better than 1.0e-05: 23
Number of HSP's better than 0.0 without gapping: 20
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 5439
Number of HSP's gapped (non-prelim): 36
length of query: 724
length of database: 30,389,216
effective HSP length: 114
effective length of query: 610
effective length of database: 23,465,084
effective search space: 14313701240
effective search space used: 14313701240
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)