ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIV2478 good C KOG2450 Energy production and conversion Aldehyde dehydrogenase
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIV2478 845873 844371 -501
(501 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YMR170c [C] KOG2450 Aldehyde dehydrogenase 704 0.0
YMR169c [C] KOG2450 Aldehyde dehydrogenase 676 0.0
SPAC922.07c [C] KOG2450 Aldehyde dehydrogenase 473 e-133
YER073w [C] KOG2450 Aldehyde dehydrogenase 431 e-120
SPAC9E9.09c [C] KOG2450 Aldehyde dehydrogenase 431 e-120
HsM4502031 [C] KOG2450 Aldehyde dehydrogenase 427 e-119
Hs10835045 [C] KOG2450 Aldehyde dehydrogenase 427 e-119
Hs21361176 [C] KOG2450 Aldehyde dehydrogenase 426 e-119
CE23852 [C] KOG2450 Aldehyde dehydrogenase 424 e-118
Hs11436533 [C] KOG2450 Aldehyde dehydrogenase 422 e-118
Hs4502041 [C] KOG2450 Aldehyde dehydrogenase 419 e-117
Hs19923115 [C] KOG2450 Aldehyde dehydrogenase 418 e-117
CE29393 [C] KOG2450 Aldehyde dehydrogenase 417 e-116
YOR374w [C] KOG2450 Aldehyde dehydrogenase 415 e-116
7297513 [C] KOG2450 Aldehyde dehydrogenase 414 e-115
Hs4502033 [C] KOG2450 Aldehyde dehydrogenase 411 e-114
At3g48000 [C] KOG2450 Aldehyde dehydrogenase 406 e-113
7301524 [C] KOG2450 Aldehyde dehydrogenase 400 e-111
At1g23800 [C] KOG2450 Aldehyde dehydrogenase 393 e-109
YPL061w [C] KOG2450 Aldehyde dehydrogenase 384 e-106
Hs18579349 [F] KOG2452 Formyltetrahydrofolate dehydrogenase 369 e-102
Hs21614513 [F] KOG2452 Formyltetrahydrofolate dehydrogenase 362 e-100
HsM7110595 [F] KOG2452 Formyltetrahydrofolate dehydrogenase 355 7e-98
At3g48170 [C] KOG2450 Aldehyde dehydrogenase 353 4e-97
At1g74920 [C] KOG2450 Aldehyde dehydrogenase 337 2e-92
SPCC550.10 [C] KOG2450 Aldehyde dehydrogenase 337 3e-92
CE05817 [F] KOG2452 Formyltetrahydrofolate dehydrogenase 323 5e-88
Hs12007648 [C] KOG2450 Aldehyde dehydrogenase 300 3e-81
CE06980 [C] KOG2450 Aldehyde dehydrogenase 288 1e-77
At1g79440 [C] KOG2451 Aldehyde dehydrogenase 280 5e-75
Hs4502047 [C] KOG2450 Aldehyde dehydrogenase 279 8e-75
7298784 [F] KOG2452 Formyltetrahydrofolate dehydrogenase 275 1e-73
CE07233 [C] KOG2450 Aldehyde dehydrogenase 274 2e-73
SPAC139.05 [C] KOG2451 Aldehyde dehydrogenase 261 1e-69
CE24573 [C] KOG2450 Aldehyde dehydrogenase 260 4e-69
7301355 [C] KOG2451 Aldehyde dehydrogenase 256 6e-68
SPAC1002.12c [C] KOG2451 Aldehyde dehydrogenase 246 4e-65
Hs4507229 [C] KOG2451 Aldehyde dehydrogenase 243 6e-64
CE10542 [C] KOG2451 Aldehyde dehydrogenase 240 3e-63
YBR006w [C] KOG2451 Aldehyde dehydrogenase 235 1e-61
At3g66658 [C] KOG2454 Betaine aldehyde dehydrogenase 207 2e-53
At2g24270 [C] KOG2450 Aldehyde dehydrogenase 201 2e-51
CE02183 [EG] KOG2449 Methylmalonate semialdehyde dehydrogenase 197 2e-50
At2g14170 [EG] KOG2449 Methylmalonate semialdehyde dehydrogenase 193 6e-49
Hs11095441 [EG] KOG2449 Methylmalonate semialdehyde dehydrogenase 189 8e-48
7290043 [EG] KOG2449 Methylmalonate semialdehyde dehydrogenase 187 3e-47
SPBC21C3.15c [C] KOG2454 Betaine aldehyde dehydrogenase 181 2e-45
CE01232 [C] KOG2453 Aldehyde dehydrogenase 178 2e-44
CE13415 [C] KOG2456 Aldehyde dehydrogenase 166 6e-41
Hs4557343 [C] KOG2453 Aldehyde dehydrogenase 163 5e-40
YHR039c [C] KOG1772 Vacuolar H+-ATPase V1 sector subunit G 157 3e-38
At1g54100 [C] KOG2453 Aldehyde dehydrogenase 156 8e-38
HsM4502035 [C] KOG2456 Aldehyde dehydrogenase 155 2e-37
7293810 [C] KOG2453 Aldehyde dehydrogenase 155 2e-37
Hs21359829 [C] KOG2456 Aldehyde dehydrogenase 154 2e-37
CE27441 [C] KOG2456 Aldehyde dehydrogenase 147 5e-35
Hs4557303 [C] KOG2456 Aldehyde dehydrogenase 144 2e-34
Hs18603595 [C] KOG2456 Aldehyde dehydrogenase 144 2e-34
At1g44170 [C] KOG2456 Aldehyde dehydrogenase 140 4e-33
CE29047 [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrogenase 137 4e-32
YHR037w [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrogenase 135 2e-31
Hs4502045 [C] KOG2456 Aldehyde dehydrogenase 134 2e-31
Hs4502043 [C] KOG2456 Aldehyde dehydrogenase 133 5e-31
7296504 [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrogenase 133 7e-31
7304212 [C] KOG2456 Aldehyde dehydrogenase 130 3e-30
Hs4502037 [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrogenase 127 4e-29
YMR110c [C] KOG2456 Aldehyde dehydrogenase 125 1e-28
Hs20546780 [C] KOG2450 Aldehyde dehydrogenase 122 1e-27
SPBC24C6.04 [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrog... 112 1e-24
At4g36250 [C] KOG2456 Aldehyde dehydrogenase 98 3e-20
7300788 [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrogenase 95 3e-19
Hs20481620 [C] KOG2456 Aldehyde dehydrogenase 90 7e-18
At4g34240 [C] KOG2456 Aldehyde dehydrogenase 83 1e-15
7294423 [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrogenase 82 1e-15
Hs20479244 [C] KOG2450 Aldehyde dehydrogenase 79 2e-14
At5g62530 [C] KOG2451 Aldehyde dehydrogenase 62 2e-09
Hs21614515 [F] KOG2452 Formyltetrahydrofolate dehydrogenase 55 2e-07
>YMR170c [C] KOG2450 Aldehyde dehydrogenase
Length = 506
Score = 704 bits (1818), Expect = 0.0
Identities = 340/501 (67%), Positives = 412/501 (81%), Gaps = 3/501 (0%)
Query: 2 SLYETVNIPQLNITYEQPLGLFINNEFVKSSDGKKIESINPSTEESIVSFFAASEKDVNS 61
+LY + IPQL I+ +QPLGLFINNEF SSDGK IE++NP+T E I SF AA+EKDV+
Sbjct: 3 TLYTDIEIPQLKISLKQPLGLFINNEFCPSSDGKTIETVNPATGEPITSFQAANEKDVDK 62
Query: 62 AVTAARDAFENNWSKTSGEQRGILLSKLFDLIERDKLLLAAIETLDSGKPYHSNSLADLE 121
AV AAR AF+N WSKTS EQRGI LS L LIE ++ LAA+ETLD+GKPYHSN+ DL
Sbjct: 63 AVKAARAAFDNVWSKTSSEQRGIYLSNLLKLIEEEQDTLAALETLDAGKPYHSNAKGDLA 122
Query: 122 QILQLTRYYAGGADKFTGGEYIPLNQDKYAYTMKVPYGVVAQIVPWNYPLAMASWKIQSC 181
QILQLTRY+AG ADKF G IPL +K+AYT+KVP+GVVAQIVPWNYPLAMA WK+Q
Sbjct: 123 QILQLTRYFAGSADKFDKGATIPLTFNKFAYTLKVPFGVVAQIVPWNYPLAMACWKLQGA 182
Query: 182 LAAGNTIVIKPAENTSLSLLYFAQLVKEAGFPPGVLNILPGYGSVTGTAMASHTDIDKIA 241
LAAGNT++IKPAENTSLSLLYFA L+K+AGFPPGV+NI+PGYGS+ G A+ASH DIDKI+
Sbjct: 183 LAAGNTVIIKPAENTSLSLLYFATLIKKAGFPPGVVNIVPGYGSLVGQALASHMDIDKIS 242
Query: 242 FTGSTAVGQKVMSLAAQSNLKAVTLECGGKSPCLIFADANLDEAIPWVAGGIFYNSGQNC 301
FTGST VG V+ + QSNLK VTLECGGKSP L+F DA+LD+AI W+A GIFYNSGQNC
Sbjct: 243 FTGSTKVGGFVLEASGQSNLKDVTLECGGKSPALVFEDADLDKAIDWIAAGIFYNSGQNC 302
Query: 302 TANSRIYVHEDIYEEFLTKFEEYAKSNWKFGAKFDPFDKDCTLGPVISKVQYDRIQSYVE 361
TANSR+YV IY++F+ KF+E AK W KFDPFD+ C +GPVIS QYDRI+SY+E
Sbjct: 303 TANSRVYVQSSIYDKFVEKFKETAKKEWDVAGKFDPFDEKCIVGPVISSTQYDRIKSYIE 362
Query: 362 HGKASEKLGFKEFAEYP---SKGYFIPPTIFSDVPNSSKLSQEEIFGPVGVVASFSTYEE 418
GK EKL + +E+P +KGYFIPPTIF+DVP +SKL Q+EIFGPV VV+ F+ Y++
Sbjct: 363 RGKREEKLDMFQTSEFPIGGAKGYFIPPTIFTDVPQTSKLLQDEIFGPVVVVSKFTNYDD 422
Query: 419 AIKLANDSSYGLASCVFSENARTTAQFARDIRAGTVWINSSNDEEISVPFGGFKMSGIGR 478
A+KLAND+ YGLAS VF+++ + FARDI+AGTVWINSSNDE+++VPFGGFKMSGIGR
Sbjct: 423 ALKLANDTCYGLASAVFTKDVKKAHMFARDIKAGTVWINSSNDEDVTVPFGGFKMSGIGR 482
Query: 479 ELGRNGVDSYLQTKAVHVNIA 499
ELG++GVD+YLQTKAVH+N++
Sbjct: 483 ELGQSGVDTYLQTKAVHINLS 503
>YMR169c [C] KOG2450 Aldehyde dehydrogenase
Length = 506
Score = 676 bits (1743), Expect = 0.0
Identities = 327/501 (65%), Positives = 401/501 (79%), Gaps = 3/501 (0%)
Query: 2 SLYETVNIPQLNITYEQPLGLFINNEFVKSSDGKKIESINPSTEESIVSFFAASEKDVNS 61
+LY + IPQL I+ +QPLGLFINNEF SSDGK IE++NP+T E I SF AA+EKDV+
Sbjct: 3 TLYTDIEIPQLKISLKQPLGLFINNEFCPSSDGKTIETVNPATGEPITSFQAANEKDVDK 62
Query: 62 AVTAARDAFENNWSKTSGEQRGILLSKLFDLIERDKLLLAAIETLDSGKPYHSNSLADLE 121
AV AAR AF+N WSKTS EQRGI LS L LIE ++ LAA+ETLD+GKP+HSN+ DL
Sbjct: 63 AVKAARAAFDNVWSKTSSEQRGIYLSNLLKLIEEEQDTLAALETLDAGKPFHSNAKQDLA 122
Query: 122 QILQLTRYYAGGADKFTGGEYIPLNQDKYAYTMKVPYGVVAQIVPWNYPLAMASWKIQSC 181
QI++LTRYYAG DKF GE IPL +K+AYT+KVP+GVVAQIVPWNYPLAMA K+Q
Sbjct: 123 QIIELTRYYAGAVDKFNMGETIPLTFNKFAYTLKVPFGVVAQIVPWNYPLAMACRKMQGA 182
Query: 182 LAAGNTIVIKPAENTSLSLLYFAQLVKEAGFPPGVLNILPGYGSVTGTAMASHTDIDKIA 241
LAAGNT++IKPAENTSLSLLYFA L+K+AGFPPGV+N++PGYGSV G A+ +H DIDKI+
Sbjct: 183 LAAGNTVIIKPAENTSLSLLYFATLIKKAGFPPGVVNVIPGYGSVVGKALGTHMDIDKIS 242
Query: 242 FTGSTAVGQKVMSLAAQSNLKAVTLECGGKSPCLIFADANLDEAIPWVAGGIFYNSGQNC 301
FTGST VG V+ + QSNLK +TLECGGKSP L+F DA+LD+AI WVA GIF+NSGQ C
Sbjct: 243 FTGSTKVGGSVLEASGQSNLKDITLECGGKSPALVFEDADLDKAIEWVANGIFFNSGQIC 302
Query: 302 TANSRIYVHEDIYEEFLTKFEEYAKSNWKFGAKFDPFDKDCTLGPVISKVQYDRIQSYVE 361
TANSR+YV IY++F+ KF+E AK W KFDPFD+ C +GPVIS QYDRI+SY+E
Sbjct: 303 TANSRVYVQSSIYDKFVEKFKETAKKEWDVAGKFDPFDEKCIVGPVISSTQYDRIKSYIE 362
Query: 362 HGKASEKLGFKEFAEYP---SKGYFIPPTIFSDVPNSSKLSQEEIFGPVGVVASFSTYEE 418
GK EKL + +E+P +KGYFIPPTIF+DVP +SKL ++EIFGPV VV+ F+ Y++
Sbjct: 363 RGKKEEKLDMFQTSEFPIGGAKGYFIPPTIFTDVPETSKLLRDEIFGPVVVVSKFTNYDD 422
Query: 419 AIKLANDSSYGLASCVFSENARTTAQFARDIRAGTVWINSSNDEEISVPFGGFKMSGIGR 478
A+KLAND+ YGLAS VF+++ + FARDI+AGTVWIN +N EE VPFGGFKMSGIGR
Sbjct: 423 ALKLANDTCYGLASAVFTKDVKKAHMFARDIKAGTVWINQTNQEEAKVPFGGFKMSGIGR 482
Query: 479 ELGRNGVDSYLQTKAVHVNIA 499
E G GVD+YLQ K+VHV+++
Sbjct: 483 ESGDTGVDNYLQIKSVHVDLS 503
>SPAC922.07c [C] KOG2450 Aldehyde dehydrogenase
Length = 496
Score = 473 bits (1216), Expect = e-133
Identities = 249/496 (50%), Positives = 339/496 (68%), Gaps = 10/496 (2%)
Query: 3 LYETVNIPQLNITYEQPLGLFINNEFVKSSDGKKIESINPSTEESIVSFFAASEKDVNSA 62
L+ ++N P + +QP+GL+IN E+ KS++ E+++PS EE I + A EK+++ A
Sbjct: 5 LFVSINFPN-GKSVKQPIGLYINGEWHKSAE--TWETVDPSIEEVIAKVYLAGEKEIDYA 61
Query: 63 VTAARDAFENNWSKTSGEQRGILLSKLFDLIERDKLLLAAIETLDSGKPYHSNSLADLEQ 122
V +A++AF+ W K G ++G LL KL +L E+ LAAIE +DSGKP SN+ D++
Sbjct: 62 VKSAKEAFKT-WKKVPGSEKGELLMKLAELTEKHADTLAAIEAMDSGKPLVSNARGDVDG 120
Query: 123 ILQLTRYYAGGADKFTGGEYIPLNQDKYAYTMKVPYGVVAQIVPWNYPLAMASWKIQSCL 182
+ L RY AG ADK G + IP +K AY + P GV QIVPWNYPL MA WKI L
Sbjct: 121 TIALLRYCAGWADKIYG-QVIPTGPEKLAYAKRTPIGVCGQIVPWNYPLNMAGWKIAPAL 179
Query: 183 AAGNTIVIKPAENTSLSLLYFAQLVKEAGFPPGVLNILPGYGSVTGTAMASHTDIDKIAF 242
AAGN I+IK AE T LSLLYFA LV+EAGFP GV+NI+ G G+V G+ MA H IDKIAF
Sbjct: 180 AAGNCIIIKSAETTPLSLLYFATLVEEAGFPKGVVNIISGLGTVAGSYMAKHPGIDKIAF 239
Query: 243 TGSTAVGQKVMSLAAQSNLKAVTLECGGKSPCLIFADANLDEAIPWVAGGIFYNSGQNCT 302
TGST VG V LAA SNLKAVTLECGGKSP L+F DA+LD+A+ W A GI YNSGQ CT
Sbjct: 240 TGSTKVGVIVQQLAA-SNLKAVTLECGGKSPFLVFEDADLDQAVKWAALGIMYNSGQICT 298
Query: 303 ANSRIYVHEDIYEEFLTKFEEYAKSNWKFGAKFDPFDKDCTLGPVISKVQYDRIQSYVEH 362
+NSRIYV + +Y++F+ F+++ ++ G PFD + +GPV++K QY+RI++Y+E
Sbjct: 299 SNSRIYVQDSVYDKFIELFKKHVIQDYIVGM---PFDDNTVVGPVVNKTQYNRIKNYIEQ 355
Query: 363 G-KASEKLGFKEFAEYPSKGYFIPPTIFSDVPNSSKLSQEEIFGPVGVVASFSTYEEAIK 421
G K KL + +GYFI PTIF+D + + +EEIFGPV ++ F T +EAI+
Sbjct: 356 GKKEGAKLVLGDEPLPLKQGYFISPTIFADCSENMTIVKEEIFGPVVAISKFKTEDEAIE 415
Query: 422 LANDSSYGLASCVFSENARTTAQFARDIRAGTVWINSSNDEEISVPFGGFKMSGIGRELG 481
AN+++YGLA+ F+++ + + ++ AG V+INS+ + +I PFGG KMSGIG ELG
Sbjct: 416 KANNTTYGLAAMCFTKDLERAHRVSDELEAGMVFINSTENSDIQAPFGGIKMSGIGNELG 475
Query: 482 RNGVDSYLQTKAVHVN 497
NG++ Y Q KAVH+N
Sbjct: 476 SNGIEMYTQIKAVHIN 491
>YER073w [C] KOG2450 Aldehyde dehydrogenase
Length = 520
Score = 431 bits (1108), Expect = e-120
Identities = 229/486 (47%), Positives = 312/486 (64%), Gaps = 7/486 (1%)
Query: 15 TYEQPLGLFINNEFVKSSDGKKIESINPSTEESIVSFFAASEKDVNSAVTAARDAFENNW 74
TYEQP GLFIN EFV S K + INPS EE I + + A E DV+ AV AA+ AFE W
Sbjct: 39 TYEQPTGLFINGEFVASKQKKTFDVINPSNEEKITTVYKAMEDDVDEAVAAAKKAFETKW 98
Query: 75 SKTSGEQRGILLSKLFDLIERDKLLLAAIETLDSGKPYHSNSLADLEQILQLTRYYAGGA 134
S E R L L DL+E+ + LAAIE++D+GK + D+ + + R G A
Sbjct: 99 SIVEPEVRAKALFNLADLVEKHQETLAAIESMDNGKSLFC-ARGDVALVSKYLRSCGGWA 157
Query: 135 DKFTGGEYIPLNQDKYAYTMKVPYGVVAQIVPWNYPLAMASWKIQSCLAAGNTIVIKPAE 194
DK G I ++ + Y++K P GV QI+PWN+PL M SWKI LA GNT+V+KPAE
Sbjct: 158 DKIYGN-VIDTGKNHFTYSIKEPLGVCGQIIPWNFPLLMWSWKIGPALATGNTVVLKPAE 216
Query: 195 NTSLSLLYFAQLVKEAGFPPGVLNILPGYGSVTGTAMASHTDIDKIAFTGSTAVGQKVMS 254
T LS L+ +QL +EAG P GV+NILPG G V G +++H D+ KIAFTGSTA G+ +M
Sbjct: 217 TTPLSALFASQLCQEAGIPAGVVNILPGSGRVVGERLSAHPDVKKIAFTGSTATGRHIMK 276
Query: 255 LAAQSNLKAVTLECGGKSPCLIFADANLDEAIPWVAGGIFYNSGQNCTANSRIYVHEDIY 314
+AA + +K VTLE GGKSP ++FADA+LD+A+ +A GIFYNSG+ C A SRIY+ + +Y
Sbjct: 277 VAADT-VKKVTLELGGKSPNIVFADADLDKAVKNIAFGIFYNSGEVCCAGSRIYIQDTVY 335
Query: 315 EEFLTKFEEYAKSNWKFGAKFDPFDKDCTLGPVISKVQYDRIQSYVEHGKASEKLGFKEF 374
EE L K ++Y +S K G DPFD++ G S Q +I YV+ K+
Sbjct: 336 EEVLQKLKDYTES-LKVG---DPFDEEVFQGAQTSDKQLHKILDYVDVAKSEGARLVTGG 391
Query: 375 AEYPSKGYFIPPTIFSDVPNSSKLSQEEIFGPVGVVASFSTYEEAIKLANDSSYGLASCV 434
A + SKGYF+ PT+F+DV ++ +EE+FGP+ V+ FST +E I +ANDS YGLA+ +
Sbjct: 392 ARHGSKGYFVKPTVFADVKGDMRIVKEEVFGPIVTVSKFSTVDEVIAMANDSQYGLAAGI 451
Query: 435 FSENARTTAQFARDIRAGTVWINSSNDEEISVPFGGFKMSGIGRELGRNGVDSYLQTKAV 494
+ + ++ ++AGTVWIN+ N+ +VPFGGF SGIGRE+G + +Y QTK+V
Sbjct: 452 HTNDINKAVDVSKRVKAGTVWINTYNNFHQNVPFGGFGQSGIGREMGEAALSNYTQTKSV 511
Query: 495 HVNIAK 500
+ I K
Sbjct: 512 RIAIDK 517
>SPAC9E9.09c [C] KOG2450 Aldehyde dehydrogenase
Length = 503
Score = 431 bits (1107), Expect = e-120
Identities = 239/489 (48%), Positives = 312/489 (62%), Gaps = 14/489 (2%)
Query: 15 TYEQPLGLFINNEFVKSSDGKKIESINPSTEESIVSFFAASEKDVNSAVTAARDAFENN- 73
TY QP+GLFINN+ V S G +++ +PSTE+ I A E+DV+ AV AR AF+ +
Sbjct: 18 TYIQPVGLFINNQHVDSVHGGRVKVYSPSTEKLICEVADADEEDVDIAVKVARAAFQTDA 77
Query: 74 -WSKTSGEQRGILLSKLFDLIERDKLLLAAIETLDSGKPYHSNSLADLEQILQLTRYYAG 132
W K S QRG LS+L D IE++ LA+IETLD+GK + + D++ RYY G
Sbjct: 78 PWRKFSSAQRGRCLSRLADCIEQNLEYLASIETLDNGKSI-TLARGDVQAAADCFRYYGG 136
Query: 133 GADKFTGGEYIPLNQDKYAYTMKVPYGVVAQIVPWNYPLAMASWKIQSCLAAGNTIVIKP 192
ADK G+ I + ++AYT P GV QI+PWN+P M +WKI +A GNTI++K
Sbjct: 137 WADK-DYGQTIETDIKRFAYTRHEPIGVCGQIIPWNFPFLMCAWKIAPAVACGNTIILKT 195
Query: 193 AENTSLSLLYFAQLVKEAGFPPGVLNILPGYGSVTGTAMASHTDIDKIAFTGSTAVGQKV 252
AE T LS L + V E GFPPGV+N+L G G G A++SH DIDK+AFTGST VG+ V
Sbjct: 196 AELTPLSALCLTKFVPECGFPPGVINVLSGDGRRCGNAISSHMDIDKVAFTGSTGVGRMV 255
Query: 253 MSLAAQSNLKAVTLECGGKSPCLIFADANLDEAIPWVAGGIFYNSGQNCTANSRIYVHED 312
M AA SNLK VTLE GGKSP ++F DA+LD A W GIFYNSGQ C A SR+YV ED
Sbjct: 256 MRAAASSNLKKVTLELGGKSPNIVFNDADLDSAAVWTNYGIFYNSGQVCCAGSRVYVQED 315
Query: 313 IYEEFLTKFEEYAKSNWKFGAKFDPFDKDCTLGPVISKVQYDRIQSYVEHG---KASEKL 369
+Y+EF+ + AK+ K G DPF +D G +SK QY+RI SY+E G A ++
Sbjct: 316 VYDEFIKRMVAKAKT-LKVG---DPFAEDTFQGAQVSKQQYERIVSYIESGIAHGAKLEI 371
Query: 370 GFKEFAEYPSKGYFIPPTIFSDVPNSSKLSQEEIFGPVGVVASFSTYEEAIKLANDSSYG 429
G K + + GYF+ PTI S+V + +EEIFGPV V F T EEAI+ N+S+YG
Sbjct: 372 GGK---RHGNLGYFVEPTILSNVTEDMAVGKEEIFGPVLAVIKFKTIEEAIRRGNNSTYG 428
Query: 430 LASCVFSENARTTAQFARDIRAGTVWINSSNDEEISVPFGGFKMSGIGRELGRNGVDSYL 489
LA+ V + N + + + AGTVW+N N +PFGG+K SGIGRELG G+ +Y
Sbjct: 429 LAAGVHTNNITNAIKVSNALEAGTVWVNCYNLLHHQIPFGGYKESGIGRELGSYGLTNYT 488
Query: 490 QTKAVHVNI 498
QTKAVH+N+
Sbjct: 489 QTKAVHINL 497
>HsM4502031 [C] KOG2450 Aldehyde dehydrogenase
Length = 501
Score = 427 bits (1099), Expect = e-119
Identities = 228/496 (45%), Positives = 312/496 (61%), Gaps = 10/496 (2%)
Query: 7 VNIPQLNITYEQPLGLFINNEFVKSSDGKKIESINPSTEESIVSFFAASEKDVNSAVTAA 66
V + L I Y + +FINNE+ S GKK NP+TEE + ++DV+ AV AA
Sbjct: 11 VLLTDLKIQYTK---IFINNEWHDSVSGKKFPVFNPATEEELCQVEEGDKEDVDKAVKAA 67
Query: 67 RDAFE--NNWSKTSGEQRGILLSKLFDLIERDKLLLAAIETLDSGKPYHSNSLADLEQIL 124
R AF+ + W +RG LL KL DLIERD+LLLA +E+++ GK Y + L+DL +
Sbjct: 68 RQAFQIGSPWRTMDASERGRLLYKLADLIERDRLLLATMESMNGGKLYSNAYLSDLAGCI 127
Query: 125 QLTRYYAGGADKFTGGEYIPLNQDKYAYTMKVPYGVVAQIVPWNYPLAMASWKIQSCLAA 184
+ RY AG ADK G IP++ + + YT P GV QI+PWN+PL M WKI L+
Sbjct: 128 KTLRYCAGWADKIQG-RTIPIDGNFFTYTRHEPIGVCGQIIPWNFPLVMLIWKIGPALSC 186
Query: 185 GNTIVIKPAENTSLSLLYFAQLVKEAGFPPGVLNILPGYGSVTGTAMASHTDIDKIAFTG 244
GNT+V+KPAE T L+ L+ A L+KEAGFPPGV+NI+PGYG G A++SH DIDK+AFTG
Sbjct: 187 GNTVVVKPAEQTPLTALHVASLIKEAGFPPGVVNIVPGYGPTAGAAISSHMDIDKVAFTG 246
Query: 245 STAVGQKVMSLAAQSNLKAVTLECGGKSPCLIFADANLDEAIPWVAGGIFYNSGQNCTAN 304
ST VG+ + A +SNLK VTLE GGKSPC++ ADA+LD A+ + G+FY+ GQ C A
Sbjct: 247 STEVGKLIKEAAGKSNLKRVTLELGGKSPCIVLADADLDNAVEFAHHGVFYHQGQCCIAA 306
Query: 305 SRIYVHEDIYEEFLTKFEEYAKSNWKFGAKFDPFDKDCTLGPVISKVQYDRIQSYVEHGK 364
SRI+V E IY+EF+ + E AK + G +P T GP I K QYD+I +E GK
Sbjct: 307 SRIFVEESIYDEFVRRSVERAK-KYILG---NPLTPGVTQGPQIDKEQYDKILDLIESGK 362
Query: 365 ASEKLGFKEFAEYPSKGYFIPPTIFSDVPNSSKLSQEEIFGPVGVVASFSTYEEAIKLAN 424
+ +KGYF+ PT+FS+V + ++++EEIFGPV + F + ++ IK AN
Sbjct: 363 KEGAKLECGGGPWGNKGYFVQPTVFSNVTDEMRIAKEEIFGPVQQIMKFKSLDDVIKRAN 422
Query: 425 DSSYGLASCVFSENARTTAQFARDIRAGTVWINSSNDEEISVPFGGFKMSGIGRELGRNG 484
++ YGL++ VF+++ + ++AGTVW+N PFGGFKMSG GRELG G
Sbjct: 423 NTFYGLSAGVFTKDIDKAITISSALQAGTVWVNCYGVVSAQCPFGGFKMSGNGRELGEYG 482
Query: 485 VDSYLQTKAVHVNIAK 500
Y + K V V I++
Sbjct: 483 FHEYTEVKTVTVKISQ 498
>Hs10835045 [C] KOG2450 Aldehyde dehydrogenase
Length = 518
Score = 427 bits (1097), Expect = e-119
Identities = 233/494 (47%), Positives = 307/494 (61%), Gaps = 16/494 (3%)
Query: 10 PQLNITYEQPLGLFINNEFVKSSDGKKIESINPSTEESIVSFFAASEKDVNSAVTAARDA 69
P L I Y + +FINNE+ S G+ NP+T E + A + D++ AV AAR A
Sbjct: 31 PNLEIKYTK---IFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLA 87
Query: 70 FE--NNWSKTSGEQRGILLSKLFDLIERDKLLLAAIETLDSGKPYHSNSLADLEQILQLT 127
F + W + +RG LL KL DL+ERD+ +LA +E+L+ GKP+ DL+ +++
Sbjct: 88 FSLGSVWRRMDASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTF 147
Query: 128 RYYAGGADKFTGGEYIPLNQDKYAYTMKVPYGVVAQIVPWNYPLAMASWKIQSCLAAGNT 187
RYYAG ADK G IP++ D + +T P GV QI+PWN+PL M +WKI L GNT
Sbjct: 148 RYYAGWADKIHGMT-IPVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNT 206
Query: 188 IVIKPAENTSLSLLYFAQLVKEAGFPPGVLNILPGYGSVTGTAMASHTDIDKIAFTGSTA 247
+VIKPAE T LS LY L+KEAGFPPGV+NILPGYG G A+ASH IDKIAFTGST
Sbjct: 207 VVIKPAEQTPLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTE 266
Query: 248 VGQKVMSLAAQSNLKAVTLECGGKSPCLIFADANLDEAIPWVAGGIFYNSGQNCTANSRI 307
VG+ + A +SNLK VTLE GGKSP +IFADA+LD A+ G+F+N GQ CTA SRI
Sbjct: 267 VGKLIQEAAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRI 326
Query: 308 YVHEDIYEEFLTKFEEYAKSNWKFGAKFDPFDKDCTLGPVISKVQYDRIQSYVEHGKASE 367
+V E IYEEF+ + E AK G+ FDP + GP I K QY++I ++ G A
Sbjct: 327 FVEESIYEEFVRRSVERAKRR-IVGSPFDPTTEQ---GPQIDKKQYNKILELIQSGVAEG 382
Query: 368 ---KLGFKEFAEYPSKGYFIPPTIFSDVPNSSKLSQEEIFGPVGVVASFSTYEEAIKLAN 424
+ G K KG+FI PT+FS+V + ++++EEIFGPV + F T +E I+ AN
Sbjct: 383 AKLECGGKGLGR---KGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERAN 439
Query: 425 DSSYGLASCVFSENARTTAQFARDIRAGTVWINSSNDEEISVPFGGFKMSGIGRELGRNG 484
+S +GL + VF+ + + ++AGTVWIN N PFGGFKMSG GRE+G G
Sbjct: 440 NSDFGLVAAVFTNDINKALTVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFG 499
Query: 485 VDSYLQTKAVHVNI 498
+ Y + K V V I
Sbjct: 500 LREYSEVKTVTVKI 513
>Hs21361176 [C] KOG2450 Aldehyde dehydrogenase
Length = 501
Score = 426 bits (1096), Expect = e-119
Identities = 228/496 (45%), Positives = 311/496 (61%), Gaps = 10/496 (2%)
Query: 7 VNIPQLNITYEQPLGLFINNEFVKSSDGKKIESINPSTEESIVSFFAASEKDVNSAVTAA 66
V + L I Y + +FINNE+ S GKK NP+TEE + ++DV+ AV AA
Sbjct: 11 VLLTDLKIQYTK---IFINNEWHDSVSGKKFPVFNPATEEELCQVEEGDKEDVDKAVKAA 67
Query: 67 RDAFE--NNWSKTSGEQRGILLSKLFDLIERDKLLLAAIETLDSGKPYHSNSLADLEQIL 124
R AF+ + W +RG LL KL DLIERD+LLLA +E+++ GK Y + L DL +
Sbjct: 68 RQAFQIGSPWRTMDASERGRLLYKLADLIERDRLLLATMESMNGGKLYSNAYLNDLAGCI 127
Query: 125 QLTRYYAGGADKFTGGEYIPLNQDKYAYTMKVPYGVVAQIVPWNYPLAMASWKIQSCLAA 184
+ RY AG ADK G IP++ + + YT P GV QI+PWN+PL M WKI L+
Sbjct: 128 KTLRYCAGWADKIQG-RTIPIDGNFFTYTRHEPIGVCGQIIPWNFPLVMLIWKIGPALSC 186
Query: 185 GNTIVIKPAENTSLSLLYFAQLVKEAGFPPGVLNILPGYGSVTGTAMASHTDIDKIAFTG 244
GNT+V+KPAE T L+ L+ A L+KEAGFPPGV+NI+PGYG G A++SH DIDK+AFTG
Sbjct: 187 GNTVVVKPAEQTPLTALHVASLIKEAGFPPGVVNIVPGYGPTAGAAISSHMDIDKVAFTG 246
Query: 245 STAVGQKVMSLAAQSNLKAVTLECGGKSPCLIFADANLDEAIPWVAGGIFYNSGQNCTAN 304
ST VG+ + A +SNLK VTLE GGKSPC++ ADA+LD A+ + G+FY+ GQ C A
Sbjct: 247 STEVGKLIKEAAGKSNLKRVTLELGGKSPCIVLADADLDNAVEFAHHGVFYHQGQCCIAA 306
Query: 305 SRIYVHEDIYEEFLTKFEEYAKSNWKFGAKFDPFDKDCTLGPVISKVQYDRIQSYVEHGK 364
SRI+V E IY+EF+ + E AK + G +P T GP I K QYD+I +E GK
Sbjct: 307 SRIFVEESIYDEFVRRSVERAK-KYILG---NPLTPGVTQGPQIDKEQYDKILDLIESGK 362
Query: 365 ASEKLGFKEFAEYPSKGYFIPPTIFSDVPNSSKLSQEEIFGPVGVVASFSTYEEAIKLAN 424
+ +KGYF+ PT+FS+V + ++++EEIFGPV + F + ++ IK AN
Sbjct: 363 KEGAKLECGGGPWGNKGYFVQPTVFSNVTDEMRIAKEEIFGPVQQIMKFKSLDDVIKRAN 422
Query: 425 DSSYGLASCVFSENARTTAQFARDIRAGTVWINSSNDEEISVPFGGFKMSGIGRELGRNG 484
++ YGL++ VF+++ + ++AGTVW+N PFGGFKMSG GRELG G
Sbjct: 423 NTFYGLSAGVFTKDIDKAITISSALQAGTVWVNCYGVVSAQCPFGGFKMSGNGRELGEYG 482
Query: 485 VDSYLQTKAVHVNIAK 500
Y + K V V I++
Sbjct: 483 FHEYTEVKTVTVKISQ 498
>CE23852 [C] KOG2450 Aldehyde dehydrogenase
Length = 537
Score = 424 bits (1089), Expect = e-118
Identities = 219/479 (45%), Positives = 309/479 (63%), Gaps = 7/479 (1%)
Query: 22 LFINNEFVKSSDGKKIESINPSTEESIVSFFAASEKDVNSAVTAARDAFE--NNWSKTSG 79
LFINNEFV + GK E +NP+ + + + DV+ AV AA+ AF+ + W +
Sbjct: 59 LFINNEFVDAKSGKTFEFVNPANGKLLAKVAEGNRDDVDIAVEAAKKAFKIGSEWRRMDA 118
Query: 80 EQRGILLSKLFDLIERDKLLLAAIETLDSGKPYHSNSLADLEQILQLTRYYAGGADKFTG 139
RG+LL++L DL+ERD+++LA++E+LD+GKPY DL ++ RYYAG ADK
Sbjct: 119 SHRGVLLNRLADLMERDRVILASLESLDNGKPYKEAYNIDLPISIKTFRYYAGYADK-NH 177
Query: 140 GEYIPLNQDKYAYTMKVPYGVVAQIVPWNYPLAMASWKIQSCLAAGNTIVIKPAENTSLS 199
G+ IP+ D + YT P GV QI+PWN+PL M +WK+ LA GNT+V+K A T LS
Sbjct: 178 GKTIPVGGDYFTYTRHEPVGVCGQIIPWNFPLLMQAWKLAPALAMGNTVVMKVAVKTPLS 237
Query: 200 LLYFAQLVKEAGFPPGVLNILPGYGSVTGTAMASHTDIDKIAFTGSTAVGQKVMSLAAQS 259
L+ A L+KEA FP GV+NI+PG G+ G A+ASH D+DK+AFTGST VG+ +M AA+S
Sbjct: 238 ALHVASLIKEAQFPEGVVNIIPGRGTDAGEAIASHMDVDKVAFTGSTEVGKTIMKAAAES 297
Query: 260 NLKAVTLECGGKSPCLIFADANLDEAIPWVAGGIFYNSGQNCTANSRIYVHEDIYEEFLT 319
N+K VTLE GGKSP ++FADA+L+EA+ +F+N GQ C+A SR +V IY+EF+
Sbjct: 298 NVKKVTLELGGKSPNIVFADADLEEAVRQSHHALFFNQGQCCSAGSRTFVEGKIYDEFVA 357
Query: 320 KFEEYAKSNWKFGAKFDPFDKDCTLGPVISKVQYDRIQSYVEHGKASEKLGFKEFAEYPS 379
K +E + DPFD++ T GP I + Q + I Y+E GK ++
Sbjct: 358 KAKELVEKT----VIGDPFDENTTQGPQIDESQVETIMKYIESGKKEGAQLVTGGVKHGD 413
Query: 380 KGYFIPPTIFSDVPNSSKLSQEEIFGPVGVVASFSTYEEAIKLANDSSYGLASCVFSENA 439
+GYF+ PTIF++V + K++QEEIFGPV +V F + EE I+ AN++ YGLA+ V + +
Sbjct: 414 QGYFVKPTIFANVNDQMKIAQEEIFGPVMIVIRFDSMEELIEKANNTIYGLAAGVVTNDL 473
Query: 440 RTTAQFARDIRAGTVWINSSNDEEISVPFGGFKMSGIGRELGRNGVDSYLQTKAVHVNI 498
Q A IRAG+VW+N + + + PFGGFK SGIGRELG G+ +Y + K V + +
Sbjct: 474 NKALQVANTIRAGSVWVNCYDVFDPAAPFGGFKQSGIGRELGEYGLAAYTEVKTVTIKV 532
>Hs11436533 [C] KOG2450 Aldehyde dehydrogenase
Length = 517
Score = 422 bits (1084), Expect = e-118
Identities = 218/479 (45%), Positives = 303/479 (62%), Gaps = 7/479 (1%)
Query: 22 LFINNEFVKSSDGKKIESINPSTEESIVSFFAASEKDVNSAVTAARDAFE--NNWSKTSG 79
+FINNE+ + K ++NPST E I ++DV+ AV AAR AF+ + W +
Sbjct: 39 IFINNEWHDAVSRKTFPTVNPSTGEVICQVAEGDKEDVDKAVKAARAAFQLGSPWRRMDA 98
Query: 80 EQRGILLSKLFDLIERDKLLLAAIETLDSGKPYHSNSLADLEQILQLTRYYAGGADKFTG 139
RG LL++L DLIERD+ LAA+ETLD+GKPY + L DL+ +L+ RYYAG ADK+ G
Sbjct: 99 SHRGRLLNRLADLIERDRTYLAALETLDNGKPYVISYLVDLDMVLKCLRYYAGWADKYHG 158
Query: 140 GEYIPLNQDKYAYTMKVPYGVVAQIVPWNYPLAMASWKIQSCLAAGNTIVIKPAENTSLS 199
+ IP++ D ++YT P GV QI+PWN+PL M +WK+ LA GN +V+K AE T L+
Sbjct: 159 -KTIPIDGDFFSYTRHEPVGVCGQIIPWNFPLLMQAWKLGPALATGNVVVMKVAEQTPLT 217
Query: 200 LLYFAQLVKEAGFPPGVLNILPGYGSVTGTAMASHTDIDKIAFTGSTAVGQKVMSLAAQS 259
LY A L+KEAGFPPGV+NI+PG+G G A+ASH D+DK+AFTGST +G+ + A S
Sbjct: 218 ALYVANLIKEAGFPPGVVNIVPGFGPTAGAAIASHEDVDKVAFTGSTEIGRVIQVAAGSS 277
Query: 260 NLKAVTLECGGKSPCLIFADANLDEAIPWVAGGIFYNSGQNCTANSRIYVHEDIYEEFLT 319
NLK VTLE GGKSP +I +DA++D A+ +F+N GQ C A SR +V EDIY+EF+
Sbjct: 278 NLKRVTLELGGKSPNIIMSDADMDWAVEQAHFALFFNQGQCCCAGSRTFVQEDIYDEFVE 337
Query: 320 KFEEYAKSNWKFGAKFDPFDKDCTLGPVISKVQYDRIQSYVEHGKASEKLGFKEFAEYPS 379
+ AKS +PFD GP + + Q+ +I Y+ GK
Sbjct: 338 RSVARAKSR----VVGNPFDSKTEQGPQVDETQFKKILGYINTGKQEGAKLLCGGGIAAD 393
Query: 380 KGYFIPPTIFSDVPNSSKLSQEEIFGPVGVVASFSTYEEAIKLANDSSYGLASCVFSENA 439
+GYFI PT+F DV + +++EEIFGPV + F T EE + AN+S+YGLA+ VF+++
Sbjct: 394 RGYFIQPTVFGDVQDGMTIAKEEIFGPVMQILKFKTIEEVVGRANNSTYGLAAAVFTKDL 453
Query: 440 RTTAQFARDIRAGTVWINSSNDEEISVPFGGFKMSGIGRELGRNGVDSYLQTKAVHVNI 498
++ ++AGTVW+N + PFGG+KMSG GRELG G+ +Y + K V V +
Sbjct: 454 DKANYLSQALQAGTVWVNCYDVFGAQSPFGGYKMSGSGRELGEYGLQAYTEVKTVTVKV 512
>Hs4502041 [C] KOG2450 Aldehyde dehydrogenase
Length = 512
Score = 419 bits (1077), Expect = e-117
Identities = 219/479 (45%), Positives = 295/479 (60%), Gaps = 7/479 (1%)
Query: 22 LFINNEFVKSSDGKKIESINPSTEESIVSFFAASEKDVNSAVTAARDAFENN--WSKTSG 79
+FINNE+ +S GKK + NPST E I + DV+ AV AA+ AF+ W +
Sbjct: 34 IFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWRRLDA 93
Query: 80 EQRGILLSKLFDLIERDKLLLAAIETLDSGKPYHSNSLADLEQILQLTRYYAGGADKFTG 139
RG LL +L DL+ERD+ LAA+ET+D+GKP+ DLE ++ RY+AG ADK G
Sbjct: 94 LSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWADKIQG 153
Query: 140 GEYIPLNQDKYAYTMKVPYGVVAQIVPWNYPLAMASWKIQSCLAAGNTIVIKPAENTSLS 199
+ IP + + +T P GV I PWN+PL M WK+ L GNT+V+KPAE T L+
Sbjct: 154 -KTIPTDDNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQTPLT 212
Query: 200 LLYFAQLVKEAGFPPGVLNILPGYGSVTGTAMASHTDIDKIAFTGSTAVGQKVMSLAAQS 259
LY L+KEAGFPPGV+NI+PG+G G A++SH I+KIAFTGST VG+ V A++S
Sbjct: 213 ALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAASRS 272
Query: 260 NLKAVTLECGGKSPCLIFADANLDEAIPWVAGGIFYNSGQNCTANSRIYVHEDIYEEFLT 319
NLK VTLE GGK+PC++ ADA+LD A+ G+F+N GQ CTA SR++V E +Y EF+
Sbjct: 273 NLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYSEFVR 332
Query: 320 KFEEYAKSNWKFGAKFDPFDKDCTLGPVISKVQYDRIQSYVEHGKASEKLGFKEFAEYPS 379
+ EYAK DPFD GP I + Q+D+I +E GK +
Sbjct: 333 RSVEYAKKR----PVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSAMED 388
Query: 380 KGYFIPPTIFSDVPNSSKLSQEEIFGPVGVVASFSTYEEAIKLANDSSYGLASCVFSENA 439
KG FI PT+FS+V ++ ++++EEIFGPV + F + EE IK AN + YGL + VF++N
Sbjct: 389 KGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTKNL 448
Query: 440 RTTAQFARDIRAGTVWINSSNDEEISVPFGGFKMSGIGRELGRNGVDSYLQTKAVHVNI 498
+ A + +GTVWIN N PFGGFKMSG GRELG + Y + K V + +
Sbjct: 449 DKALKLASALESGTVWINCYNALYAQAPFGGFKMSGNGRELGEYALAEYTEVKTVTIKL 507
>Hs19923115 [C] KOG2450 Aldehyde dehydrogenase
Length = 517
Score = 418 bits (1075), Expect = e-117
Identities = 219/491 (44%), Positives = 310/491 (62%), Gaps = 16/491 (3%)
Query: 13 NITYEQPLGLFINNEFVKSSDGKKIESINPSTEESIVSFFAASEKDVNSAVTAARDAFE- 71
+I Y Q LFINNE+ + K ++NP+T E I DV+ AV AAR+AF
Sbjct: 33 DIPYNQ---LFINNEWQDAVSKKTFPTVNPTTGEVIGHVAEGDRADVDRAVKAAREAFRL 89
Query: 72 -NNWSKTSGEQRGILLSKLFDLIERDKLLLAAIETLDSGKPYHSNSLADLEQILQLTRYY 130
+ W + +RG LL+ L DL+ERD++ LA++ETLD+GKP+ + DL++++++ RY+
Sbjct: 90 GSPWRRMDASERGRLLNLLADLVERDRVYLASLETLDNGKPFQESYALDLDEVIKVYRYF 149
Query: 131 AGGADKFTGGEYIPLNQDKYAYTMKVPYGVVAQIVPWNYPLAMASWKIQSCLAAGNTIVI 190
AG ADK+ G + IP++ + +T P GV QI+PWN+PL M WK+ LA GNT+V+
Sbjct: 150 AGWADKWHG-KTIPMDGQHFCFTRHEPVGVCGQIIPWNFPLVMQGWKLAPALATGNTVVM 208
Query: 191 KPAENTSLSLLYFAQLVKEAGFPPGVLNILPGYGSVTGTAMASHTDIDKIAFTGSTAVGQ 250
K AE T LS LY A L+KEAGFPPGV+NI+ GYG G A+A H D+DK+AFTGST VG
Sbjct: 209 KVAEQTPLSALYLASLIKEAGFPPGVVNIITGYGPTAGAAIAQHMDVDKVAFTGSTEVGH 268
Query: 251 KVMSLAAQSNLKAVTLECGGKSPCLIFADANLDEAIPWVAGGIFYNSGQNCTANSRIYVH 310
+ A SNLK VTLE GGKSP ++ ADA+++ A+ +F+N GQ C A SR +V
Sbjct: 269 LIQKAAGDSNLKRVTLELGGKSPSIVLADADMEHAVEQCHEALFFNMGQCCCAGSRTFVE 328
Query: 311 EDIYEEFLTKFEEYAKSNWKFGAKFDPFDKDCTLGPVISKVQYDRIQSYVEHG-KASEKL 369
E IY EFL + E AK K G +PF+ D GP + K Q++R+ Y++ G K KL
Sbjct: 329 ESIYNEFLERTVEKAKQR-KVG---NPFELDTQQGPQVDKEQFERVLGYIQLGQKEGAKL 384
Query: 370 --GFKEFAEYPSKGYFIPPTIFSDVPNSSKLSQEEIFGPVGVVASFSTYEEAIKLANDSS 427
G + F E +G+FI PT+F V + ++++EEIFGPV + F EE ++ AN++
Sbjct: 385 LCGGERFGE---RGFFIKPTVFGGVQDDMRIAKEEIFGPVQPLFKFKKIEEVVERANNTR 441
Query: 428 YGLASCVFSENARTTAQFARDIRAGTVWINSSNDEEISVPFGGFKMSGIGRELGRNGVDS 487
YGLA+ VF+ + F + ++AGTVW+N+ N PFGGFK SG GRELG +G+ +
Sbjct: 442 YGLAAAVFTRDLDKAMYFTQALQAGTVWVNTYNIVTCHTPFGGFKESGNGRELGEDGLKA 501
Query: 488 YLQTKAVHVNI 498
Y + K V + +
Sbjct: 502 YTEVKTVTIKV 512
>CE29393 [C] KOG2450 Aldehyde dehydrogenase
Length = 510
Score = 417 bits (1073), Expect = e-116
Identities = 218/491 (44%), Positives = 310/491 (62%), Gaps = 7/491 (1%)
Query: 10 PQLNITYEQPLGLFINNEFVKSSDGKKIESINPSTEESIVSFFAASEKDVNSAVTAARDA 69
P L+ Q G+FINNEFV + GK E+INP+ + + + DVN AV AA++A
Sbjct: 20 PGLSNMKPQYTGIFINNEFVPAKSGKTFETINPANGKVLAQVAEGDKTDVNIAVKAAQNA 79
Query: 70 FE--NNWSKTSGEQRGILLSKLFDLIERDKLLLAAIETLDSGKPYHSNSLADLEQILQLT 127
F + W + QRG+LL++L DL+ERD+++LA++E+LD+GKPY ADL ++
Sbjct: 80 FRIGSEWRRMDASQRGVLLNRLADLMERDRVILASLESLDNGKPYAVAYNADLPLSIKTL 139
Query: 128 RYYAGGADKFTGGEYIPLNQDKYAYTMKVPYGVVAQIVPWNYPLAMASWKIQSCLAAGNT 187
R ADK G+ IP+ D + YT P GV QI+PWN+PL M +WK+ LA GNT
Sbjct: 140 RLLRRMADK-NHGKTIPIEGDYFTYTRHEPVGVCGQIIPWNFPLLMQAWKLGPALAMGNT 198
Query: 188 IVIKPAENTSLSLLYFAQLVKEAGFPPGVLNILPGYGSVTGTAMASHTDIDKIAFTGSTA 247
+V+K AE T LS L+ A L KEAGFP GV+NI+PGYG G A++SH D+DK+AFTGST
Sbjct: 199 VVMKVAEQTPLSALHVAALTKEAGFPDGVVNIIPGYGHTAGQAISSHMDVDKVAFTGSTE 258
Query: 248 VGQKVMSLAAQSNLKAVTLECGGKSPCLIFADANLDEAIPWVAGGIFYNSGQNCTANSRI 307
VG+ VM AA+SN+K VTLE GGKSP +IFADA+L++++ G+F+N GQ C A SR
Sbjct: 259 VGRLVMKAAAESNVKKVTLELGGKSPNIIFADADLNDSVHQANHGLFFNQGQCCCAGSRT 318
Query: 308 YVHEDIYEEFLTKFEEYAKSNWKFGAKFDPFDKDCTLGPVISKVQYDRIQSYVEHGKASE 367
+V IY++F+ + +E A+ DPFD T GP + Q + I Y+ GK
Sbjct: 319 FVEGKIYDDFVARSKELAEK----AVIGDPFDLKTTQGPQVDGKQVETILKYIAAGKKDG 374
Query: 368 KLGFKEFAEYPSKGYFIPPTIFSDVPNSSKLSQEEIFGPVGVVASFSTYEEAIKLANDSS 427
A++ +G+F+ PTIF++V + ++QEEIFGPV + F T EE ++ AN++
Sbjct: 375 AQLVTGGAKHGDQGHFVKPTIFANVKDQMTIAQEEIFGPVMTIIRFDTMEELVEKANNTI 434
Query: 428 YGLASCVFSENARTTAQFARDIRAGTVWINSSNDEEISVPFGGFKMSGIGRELGRNGVDS 487
YGLA+ V +++ A RAG+VW+N + + + PFGGFK SGIGRELG G+++
Sbjct: 435 YGLAAGVMTKDIDKALHIANATRAGSVWVNCYDVFDAAAPFGGFKQSGIGRELGEYGLEA 494
Query: 488 YLQTKAVHVNI 498
Y + K V + +
Sbjct: 495 YTEVKTVTIKV 505
>YOR374w [C] KOG2450 Aldehyde dehydrogenase
Length = 519
Score = 415 bits (1066), Expect = e-116
Identities = 223/486 (45%), Positives = 305/486 (61%), Gaps = 8/486 (1%)
Query: 14 ITYEQPLGLFINNEFVKSSDGKKIESINPSTEESIVSFFAASEKDVNSAVTAARDAFEN- 72
+ YEQP GLFINN+FV S K E INPSTEE I + E DV AV AA AF N
Sbjct: 39 LEYEQPTGLFINNKFVPSKQNKTFEVINPSTEEEICHIYEGREDDVEEAVQAADRAFSNG 98
Query: 73 NWSKTSGEQRGILLSKLFDLIERDKLLLAAIETLDSGKPYHSNSLADLEQILQLTRYYAG 132
+W+ RG L +L +LIE+DK ++A+IETLD+GK S+S D++ ++ + AG
Sbjct: 99 SWNGIDPIDRGKALYRLAELIEQDKDVIASIETLDNGKAI-SSSRGDVDLVINYLKSSAG 157
Query: 133 GADKFTGGEYIPLNQDKYAYTMKVPYGVVAQIVPWNYPLAMASWKIQSCLAAGNTIVIKP 192
ADK G I + ++YT + P GV QI+PWN+PL M +WKI L GNT+V+K
Sbjct: 158 FADKIDG-RMIDTGRTHFSYTKRQPLGVCGQIIPWNFPLLMWAWKIAPALVTGNTVVLKT 216
Query: 193 AENTSLSLLYFAQLVKEAGFPPGVLNILPGYGSVTGTAMASHTDIDKIAFTGSTAVGQKV 252
AE+T LS LY ++ + +AG PPGV+NI+ G+G + G A+ +H I K+AFTGSTA G+ +
Sbjct: 217 AESTPLSALYVSKYIPQAGIPPGVINIVSGFGKIVGEAITNHPKIKKVAFTGSTATGRHI 276
Query: 253 MSLAAQSNLKAVTLECGGKSPCLIFADANLDEAIPWVAGGIFYNSGQNCTANSRIYVHED 312
AA + LK VTLE GGKSP ++FADA L +A+ + GI+YNSG+ C A SR+YV E
Sbjct: 277 YQSAA-AGLKKVTLELGGKSPNIVFADAELKKAVQNIILGIYYNSGEVCCAGSRVYVEES 335
Query: 313 IYEEFLTKFEEYAKSNWKFGAKFDPFDKDCTLGPVISKVQYDRIQSYVEHGKASEKLGFK 372
IY++F+ +F+ A + K G DPFD+ G S++Q ++I YV+ GK
Sbjct: 336 IYDKFIEEFKA-ASESIKVG---DPFDESTFQGAQTSQMQLNKILKYVDIGKNEGATLIT 391
Query: 373 EFAEYPSKGYFIPPTIFSDVPNSSKLSQEEIFGPVGVVASFSTYEEAIKLANDSSYGLAS 432
SKGYFI PT+F DV ++ +EEIFGPV V F + +E I +ANDS YGLA+
Sbjct: 392 GGERLGSKGYFIKPTVFGDVKEDMRIVKEEIFGPVVTVTKFKSADEVINMANDSEYGLAA 451
Query: 433 CVFSENARTTAQFARDIRAGTVWINSSNDEEISVPFGGFKMSGIGRELGRNGVDSYLQTK 492
+ + N T + A + AGTVWIN+ ND +VPFGGF SG+GRE+ + + +YLQ K
Sbjct: 452 GIHTSNINTALKVADRVNAGTVWINTYNDFHHAVPFGGFNASGLGREMSVDALQNYLQVK 511
Query: 493 AVHVNI 498
AV +
Sbjct: 512 AVRAKL 517
>7297513 [C] KOG2450 Aldehyde dehydrogenase
Length = 520
Score = 414 bits (1063), Expect = e-115
Identities = 220/486 (45%), Positives = 314/486 (64%), Gaps = 15/486 (3%)
Query: 21 GLFINNEFVKSSDGKKIESINPSTEESIVSFFAASEKDVNSAVTAARDAFE--NNWSKTS 78
G+FINNE+ KS GK E+INP+T E I A ++D++ AV AAR+AF+ + W +
Sbjct: 41 GVFINNEWHKSKSGKIFETINPTTAEVIAEIQCADKEDIDIAVQAARNAFKLGSPWRRMD 100
Query: 79 GEQRGILLSKLFDLIERDKLLLAAIETLDSGKPYHSNSLADLEQILQLTRYYAGGADKFT 138
+RG LL +L DL+ERD++ LA++ETLD+GKPY + DL ++ RY+AG ADK
Sbjct: 101 ASERGRLLYRLADLMERDQVYLASLETLDNGKPYSMSYNVDLPTAIKNLRYFAGWADK-N 159
Query: 139 GGEYIPLNQDKYAYTMKVPYGVVAQIVPWNYPLAMASWKIQSCLAAGNTIVIKPAENTSL 198
G+ IP++ D + YT P GV QI+PWN+P+ M +WK+ LA GNTIV+KPAE TSL
Sbjct: 160 HGKTIPMDGDFFTYTRHEPVGVCGQIIPWNFPILMMAWKLGPALATGNTIVLKPAEQTSL 219
Query: 199 SLLYFAQLVKEAGFPPGVLNILPGYGSVTGTAMASHTDIDKIAFTGSTAVGQKVMSLAAQ 258
+ LY AQLVKEAGFP GV+N++PG+G+ G A+A+H D+DK+AFTGST VG+ + +
Sbjct: 220 TALYIAQLVKEAGFPEGVVNVVPGFGT-AGAALANHCDVDKVAFTGSTDVGKLIQLASGN 278
Query: 259 SNLKAVTLECGGKSPCLIFADANLDEAIPWVAGGIFYNSGQNCTANSRIYVHEDIYEEFL 318
+NLK VTLE GGKSP +I +D ++D A+ G+F+N GQ C A SR +V + IY+EF+
Sbjct: 279 TNLKRVTLELGGKSPNIILSDTDMDYAVETAHFGLFFNMGQCCCAGSRTFVEDKIYDEFV 338
Query: 319 TKFEEYAKSNWKFGAKFDPFDKDCTLGPVISKVQYDRIQSYVEHGKASEKLGFKEFA--E 376
+ E AK +PFD + GP +++ Q ++I ++ GK K G K A
Sbjct: 339 ERSAERAKKR----TVGNPFDLNTEQGPQVNEEQMEKILGMIKTGK---KQGAKLVAGGS 391
Query: 377 YPS--KGYFIPPTIFSDVPNSSKLSQEEIFGPVGVVASFSTYEEAIKLANDSSYGLASCV 434
P GYF+ PT+F+DV + +++EEIFGPV + F +E I+ AN+S YGLA+ V
Sbjct: 392 RPEGLPGYFVQPTVFADVQDDMTIAREEIFGPVQQLIRFKKLDEVIERANNSEYGLAAAV 451
Query: 435 FSENARTTAQFARDIRAGTVWINSSNDEEISVPFGGFKMSGIGRELGRNGVDSYLQTKAV 494
F+++ +RAGTVW+N+ N PFGG+KMSG GRE G + +Y + K+V
Sbjct: 452 FTKDLDKANYIVGGLRAGTVWVNTYNVLAAQAPFGGYKMSGHGRENGEYALSNYTEVKSV 511
Query: 495 HVNIAK 500
V +A+
Sbjct: 512 IVKVAQ 517
>Hs4502033 [C] KOG2450 Aldehyde dehydrogenase
Length = 516
Score = 411 bits (1057), Expect = e-114
Identities = 213/479 (44%), Positives = 298/479 (61%), Gaps = 7/479 (1%)
Query: 22 LFINNEFVKSSDGKKIESINPSTEESIVSFFAASEKDVNSAVTAARDAFE--NNWSKTSG 79
+FINNE+ + K ++NPST E I ++DV+ A AF+ + W +
Sbjct: 38 IFINNEWHDAVSRKTFPTVNPSTGEVICQVAEGDKEDVDKAREGRPGAFQLGSPWRRMDA 97
Query: 80 EQRGILLSKLFDLIERDKLLLAAIETLDSGKPYHSNSLADLEQILQLTRYYAGGADKFTG 139
G LL++L DLIERD+ LAA+ETLD+GKPY + L DL+ +L+ RYYAG ADK+ G
Sbjct: 98 SHSGRLLNRLADLIERDRTYLAALETLDNGKPYVISYLVDLDMVLKCLRYYAGWADKYHG 157
Query: 140 GEYIPLNQDKYAYTMKVPYGVVAQIVPWNYPLAMASWKIQSCLAAGNTIVIKPAENTSLS 199
+ IP++ D ++YT P GV QI+PWN+PL M +WK+ LA GN +V+K AE T L+
Sbjct: 158 -KTIPIDGDFFSYTRHEPVGVCGQIIPWNFPLLMQAWKLGPALATGNVVVMKVAEQTPLT 216
Query: 200 LLYFAQLVKEAGFPPGVLNILPGYGSVTGTAMASHTDIDKIAFTGSTAVGQKVMSLAAQS 259
LY A L+KEAGFPPGV+NI+PG+G G A+ASH D+DK+AFTGST +G+ + A S
Sbjct: 217 ALYVANLIKEAGFPPGVVNIVPGFGPTAGAAIASHEDVDKVAFTGSTEIGRVIQVAAGSS 276
Query: 260 NLKAVTLECGGKSPCLIFADANLDEAIPWVAGGIFYNSGQNCTANSRIYVHEDIYEEFLT 319
NLK VTLE GGKSP +I +DA++D A+ +F+N GQ C A SR +V EDIY+EF+
Sbjct: 277 NLKRVTLELGGKSPNIIMSDADMDWAVEQAHFALFFNQGQCCCAGSRTFVQEDIYDEFVV 336
Query: 320 KFEEYAKSNWKFGAKFDPFDKDCTLGPVISKVQYDRIQSYVEHGKASEKLGFKEFAEYPS 379
+ AKS +PFD GP + + Q+ +I Y+ GK
Sbjct: 337 RSVARAKSR----VVGNPFDSKTEQGPQVDETQFKKILGYINTGKQEGAKLLCGGGIAAD 392
Query: 380 KGYFIPPTIFSDVPNSSKLSQEEIFGPVGVVASFSTYEEAIKLANDSSYGLASCVFSENA 439
+GYFI PT+F DV + +++EEIFGPV + F T EE + AN+S+YGLA+ VF+++
Sbjct: 393 RGYFIQPTVFGDVQDGMTIAKEEIFGPVMQILKFKTIEEVVGRANNSTYGLAAAVFTKDL 452
Query: 440 RTTAQFARDIRAGTVWINSSNDEEISVPFGGFKMSGIGRELGRNGVDSYLQTKAVHVNI 498
++ ++AGTVW+N + PFGG+KMSG GRELG G+ +Y + K V V +
Sbjct: 453 DKANYLSQALQAGTVWVNCYDVFGAQSPFGGYKMSGSGRELGEYGLQAYTEVKTVTVKV 511
>At3g48000 [C] KOG2450 Aldehyde dehydrogenase
Length = 538
Score = 406 bits (1043), Expect = e-113
Identities = 216/491 (43%), Positives = 305/491 (61%), Gaps = 10/491 (2%)
Query: 5 ETVNIPQLNITYEQPLGLFINNEFVKSSDGKKIESINPSTEESIVSFFAASEKDVNSAVT 64
E +N P + +++ Q L IN FV S+ GK +++P T E I +D+N AV
Sbjct: 47 EIIN-PSVQVSHTQ---LLINGNFVDSASGKTFPTLDPRTGEVIAHVAEGDAEDINRAVK 102
Query: 65 AARDAF-ENNWSKTSGEQRGILLSKLFDLIERDKLLLAAIETLDSGKPYHSNSLADLEQI 123
AAR AF E W K S +R +L + DL+E+ LA++ET D+GKPY + A++
Sbjct: 103 AARTAFDEGPWPKMSAYERSRVLLRFADLVEKHSEELASLETWDNGKPYQQSLTAEIPMF 162
Query: 124 LQLTRYYAGGADKFTGGEYIPLNQDKYAYTMKVPYGVVAQIVPWNYPLAMASWKIQSCLA 183
+L RYYAG ADK G IP + + +T+ P GV QI+PWN+PL M +WK+ LA
Sbjct: 163 ARLFRYYAGWADKIHGLT-IPADGNYQVHTLHEPIGVAGQIIPWNFPLLMFAWKVGPALA 221
Query: 184 AGNTIVIKPAENTSLSLLYFAQLVKEAGFPPGVLNILPGYGSVTGTAMASHTDIDKIAFT 243
GNTIV+K AE T L+ Y +L EAG PPGVLNI+ G+G+ G A+ASH D+DK+AFT
Sbjct: 222 CGNTIVLKTAEQTPLTAFYAGKLFLEAGLPPGVLNIVSGFGATAGAALASHMDVDKLAFT 281
Query: 244 GSTAVGQKVMSLAAQSNLKAVTLECGGKSPCLIFADANLDEAIPWVAGGIFYNSGQNCTA 303
GST G+ ++ LAA SNLK VTLE GGKSP ++F DA++D+A+ +F+N GQ C A
Sbjct: 282 GSTDTGKVILGLAANSNLKPVTLELGGKSPFIVFEDADIDKAVELAHFALFFNQGQCCCA 341
Query: 304 NSRIYVHEDIYEEFLTKFEEYAKSNWKFGAKFDPFDKDCTLGPVISKVQYDRIQSYVEHG 363
SR +VHE +Y+EF+ K + A DPF K GP I Q++++ Y++ G
Sbjct: 342 GSRTFVHEKVYDEFVEKSKARALKR----VVGDPFRKGIEQGPQIDLKQFEKVMKYIKSG 397
Query: 364 KASEKLGFKEFAEYPSKGYFIPPTIFSDVPNSSKLSQEEIFGPVGVVASFSTYEEAIKLA 423
S + KGYFI PT+FS+V + ++Q+EIFGPV + FS +E IK A
Sbjct: 398 IESNATLECGGDQIGDKGYFIQPTVFSNVKDDMLIAQDEIFGPVQSILKFSDVDEVIKRA 457
Query: 424 NDSSYGLASCVFSENARTTAQFARDIRAGTVWINSSNDEEISVPFGGFKMSGIGRELGRN 483
N++ YGLA+ VF++N T + +R ++AGTVW+N + + ++PFGG+KMSG GRE G
Sbjct: 458 NETKYGLAAGVFTKNLDTANRVSRALKAGTVWVNCFDVFDAAIPFGGYKMSGNGREKGIY 517
Query: 484 GVDSYLQTKAV 494
+++YLQ KAV
Sbjct: 518 SLNNYLQIKAV 528
>7301524 [C] KOG2450 Aldehyde dehydrogenase
Length = 659
Score = 400 bits (1029), Expect = e-111
Identities = 220/482 (45%), Positives = 306/482 (62%), Gaps = 15/482 (3%)
Query: 22 LFINNEFVKSSDGKKIESINPSTEESIVSFFAASEKDVNSAVTAARDAF--ENNWSKTSG 79
LFINNEFV S GK + NP+T + IV + D++ AV AA+ AF ++ W K S
Sbjct: 187 LFINNEFVDSVSGKTFATFNPATSKEIVQVSEGDKADIDLAVKAAKKAFHRDSEWRKLSP 246
Query: 80 EQRGILLSKLFDLIERDKLLLAAIETLDSGKPYHSNSLADLEQILQLTRYYAGGADKFTG 139
QR L++KL L++RDK LA++ET D+GKPY + +L D+ + +YYAG DKF G
Sbjct: 247 LQRTNLMNKLCALMDRDKAFLASLETQDNGKPY-AEALFDVTYSILTLQYYAGWTDKFFG 305
Query: 140 GEYIPLNQDKYAYTMKVPYGVVAQIVPWNYPLAMASWKIQSCLAAGNTIVIKPAENTSLS 199
+ IP + T K P GVV QI+PWNYPL M +WK LA G TI++KPAE T L+
Sbjct: 306 -DTIPAG-GFVSMTRKEPVGVVGQIIPWNYPLLMLAWKWGPALAVGCTIIMKPAEQTPLT 363
Query: 200 LLYFAQLVKEAGFPPGVLNILPGYGSVTGTAMASHTDIDKIAFTGSTAVGQKVMSLAAQS 259
L+ A L KEAGFP GV+N++ G+G G A+++H DI K+AFTGS +G+ VM AA S
Sbjct: 364 ALHMAALAKEAGFPAGVINVVNGFGPTAGAAISAHPDIAKVAFTGSVEIGRIVMQAAATS 423
Query: 260 NLKAVTLECGGKSPCLIFADANLDEAIPWVAGGIFYNSGQNCTANSRIYVHEDIYEEFLT 319
NLK V+LE GGKSP ++F DA++D A+ +F N GQ+C A SR YVHE IY+EF+
Sbjct: 424 NLKRVSLELGGKSPVVVFDDADIDFAVETTHEALFSNHGQSCCAGSRTYVHEKIYDEFVA 483
Query: 320 KFEEYAKSNWKFGAKFDPFDKDCTLGPVISKVQYDRIQSYVEHGK---ASEKLGFKEFAE 376
K AK+ K G +PF+++ GP I ++ Y+E GK A + G K
Sbjct: 484 KAAAKAKAR-KVG---NPFEQNVQQGPQIDDDMLTKVLGYIESGKKEGAKLQAGGKRIG- 538
Query: 377 YPSKGYFIPPTIFSDVPNSSKLSQEEIFGPVGVVASFSTYEEAIKLANDSSYGLASCVFS 436
+ G+F+ PT+FSDV + +++QEEIFGPV + FS+ EE I AN+ YGLA+ V +
Sbjct: 539 --NVGFFVEPTVFSDVKDDMRIAQEEIFGPVQSIFKFSSLEEMIDRANNVQYGLAAGVIT 596
Query: 437 ENARTTAQFARDIRAGTVWINSSNDEEISVPFGGFKMSGIGRELGRNGVDSYLQTKAVHV 496
+ +FA ++ AG+VWIN + S PFGG+K SGIGRELG++G+D+YL+TK + +
Sbjct: 597 NDINKALKFANNVDAGSVWINCYDAVLPSTPFGGYKHSGIGRELGKDGLDNYLETKTITM 656
Query: 497 NI 498
+
Sbjct: 657 KL 658
>At1g23800 [C] KOG2450 Aldehyde dehydrogenase
Length = 508
Score = 393 bits (1009), Expect = e-109
Identities = 211/491 (42%), Positives = 298/491 (59%), Gaps = 9/491 (1%)
Query: 5 ETVNIPQLNITYEQPLGLFINNEFVKSSDGKKIESINPSTEESIVSFFAASEKDVNSAVT 64
E P + + + Q L I FV + GK +++P E I +DVN AV
Sbjct: 16 ENTITPPVKVEHTQ---LLIGGRFVDAVSGKTFPTLDPRNGEVIAQVSEGDAEDVNRAVA 72
Query: 65 AARDAF-ENNWSKTSGEQRGILLSKLFDLIERDKLLLAAIETLDSGKPYHSNSLADLEQI 123
AAR AF E W K + +R +L + DLIE+ +AA+ET D+GKPY ++ ++ +
Sbjct: 73 AARKAFDEGPWPKMTAYERSKILFRFADLIEKHNDEIAALETWDNGKPYEQSAQIEVPML 132
Query: 124 LQLTRYYAGGADKFTGGEYIPLNQDKYAYTMKVPYGVVAQIVPWNYPLAMASWKIQSCLA 183
++ RYYAG ADK G +P + + T+ P GV QI+PWN+PL M SWK+ LA
Sbjct: 133 ARVFRYYAGWADKIHGMT-MPGDGPHHVQTLHEPIGVAGQIIPWNFPLLMLSWKLGPALA 191
Query: 184 AGNTIVIKPAENTSLSLLYFAQLVKEAGFPPGVLNILPGYGSVTGTAMASHTDIDKIAFT 243
GNT+V+K AE T LS L +L+ EAG P GV+NI+ G+G+ G A+ASH D+DK+AFT
Sbjct: 192 CGNTVVLKTAEQTPLSALLVGKLLHEAGLPDGVVNIVSGFGATAGAAIASHMDVDKVAFT 251
Query: 244 GSTAVGQKVMSLAAQSNLKAVTLECGGKSPCLIFADANLDEAIPWVAGGIFYNSGQNCTA 303
GST VG+ ++ LA++SNLKAVTLE GGKSP ++ DA++D+A+ +F+N GQ C A
Sbjct: 252 GSTDVGKIILELASKSNLKAVTLELGGKSPFIVCEDADVDQAVELAHFALFFNQGQCCCA 311
Query: 304 NSRIYVHEDIYEEFLTKFEEYAKSNWKFGAKFDPFDKDCTLGPVISKVQYDRIQSYVEHG 363
SR +VHE +Y+EF+ K AK+ DPF GP + Q+++I Y++HG
Sbjct: 312 GSRTFVHERVYDEFVEK----AKARALKRNVGDPFKSGIEQGPQVDSEQFNKILKYIKHG 367
Query: 364 KASEKLGFKEFAEYPSKGYFIPPTIFSDVPNSSKLSQEEIFGPVGVVASFSTYEEAIKLA 423
+ SKGY+I PT+FSDV + ++ +EIFGPV + F +E I A
Sbjct: 368 VEAGATLQAGGDRLGSKGYYIQPTVFSDVKDDMLIATDEIFGPVQTILKFKDLDEVIARA 427
Query: 424 NDSSYGLASCVFSENARTTAQFARDIRAGTVWINSSNDEEISVPFGGFKMSGIGRELGRN 483
N+S YGLA+ VF++N T + R +R GTVWIN + + S+PFGG+KMSGIGRE G
Sbjct: 428 NNSRYGLAAGVFTQNLDTAHRLMRALRVGTVWINCFDVLDASIPFGGYKMSGIGREKGIY 487
Query: 484 GVDSYLQTKAV 494
+++YLQ KAV
Sbjct: 488 SLNNYLQVKAV 498
>YPL061w [C] KOG2450 Aldehyde dehydrogenase
Length = 500
Score = 384 bits (986), Expect = e-106
Identities = 209/486 (43%), Positives = 294/486 (60%), Gaps = 6/486 (1%)
Query: 14 ITYEQPLGLFINNEFVKSSDGKKIESINPSTEESIVSFFAASEKDVNSAVTAARDAF-EN 72
+TYEQP GLFINN+F+K+ DGK +PSTE ++ +A+ +DV A+ A AF +
Sbjct: 20 LTYEQPTGLFINNKFMKAQDGKTYPVEDPSTENTVCEVSSATTEDVEYAIECADRAFHDT 79
Query: 73 NWSKTSGEQRGILLSKLFDLIERDKLLLAAIETLDSGKPYHSNSLADLEQILQLTRYYAG 132
W+ +RG LLSKL D +E L+++IE LD+GK + + D+ + R A
Sbjct: 80 EWATQDPRERGRLLSKLADELESQIDLVSSIEALDNGKTL-ALARGDVTIAINCLRDAAA 138
Query: 133 GADKFTGGEYIPLNQDKYAYTMKVPYGVVAQIVPWNYPLAMASWKIQSCLAAGNTIVIKP 192
ADK G I +T P GV QI+PWN+P+ M +WKI LA GN ++KP
Sbjct: 139 YADK-VNGRTINTGDGYMNFTTLEPIGVCGQIIPWNFPIMMLAWKIAPALAMGNVCILKP 197
Query: 193 AENTSLSLLYFAQLVKEAGFPPGVLNILPGYGSVTGTAMASHTDIDKIAFTGSTAVGQKV 252
A T L+ LYFA L K+ G P GV+NI+PG G G A+ + I K+AFTGST VG+ V
Sbjct: 198 AAVTPLNALYFASLCKKVGIPAGVVNIVPGPGRTVGAALTNDPRIRKLAFTGSTEVGKSV 257
Query: 253 MSLAAQSNLKAVTLECGGKSPCLIFADANLDEAIPWVAGGIFYNSGQNCTANSRIYVHED 312
+++SNLK +TLE GGKS L+F DAN+ + +P + GIF N+GQ C++ SRIYV E
Sbjct: 258 AVDSSESNLKKITLELGGKSAHLVFDDANIKKTLPNLVNGIFKNAGQICSSGSRIYVQEG 317
Query: 313 IYEEFLTKFEEYAKSNWKFGAKFDPFDKDCTLGPVISKVQYDRIQSYVEHGKASEKLGFK 372
IY+E L F+ Y ++ K G +PFDK G + ++ Q+D I +Y++ GK
Sbjct: 318 IYDELLAAFKAYLETEIKVG---NPFDKANFQGAITNRQQFDTIMNYIDIGKKEGAKILT 374
Query: 373 EFAEYPSKGYFIPPTIFSDVPNSSKLSQEEIFGPVGVVASFSTYEEAIKLANDSSYGLAS 432
+ KGYFI PT+F DV ++ +EEIFGPV VA F T EE +++AN S +GL S
Sbjct: 375 GGEKVGDKGYFIRPTVFYDVNEDMRIVKEEIFGPVVTVAKFKTLEEGVEMANSSEFGLGS 434
Query: 433 CVFSENARTTAQFARDIRAGTVWINSSNDEEISVPFGGFKMSGIGRELGRNGVDSYLQTK 492
+ +E+ T + A+ ++AGTVWIN+ ND + VPFGG K SG GRE+G +Y + K
Sbjct: 435 GIETESLSTGLKVAKMLKAGTVWINTYNDFDSRVPFGGVKQSGYGREMGEEVYHAYTEVK 494
Query: 493 AVHVNI 498
AV + +
Sbjct: 495 AVRIKL 500
>Hs18579349 [F] KOG2452 Formyltetrahydrofolate dehydrogenase
Length = 975
Score = 369 bits (947), Expect = e-102
Identities = 205/502 (40%), Positives = 295/502 (57%), Gaps = 25/502 (4%)
Query: 14 ITYEQPLGLFINNEFVKSSDGKKIESINPSTEESIVSFFAASEKDVNSAVTAARDAFENN 73
I + P FIN +F + DGK ++INP+ +I AS DV+ AV AA+DAFEN
Sbjct: 437 IMVKMPYQCFINGQFTDADDGKTYDTINPTDGSTICKVSYASLADVDKAVAAAKDAFENG 496
Query: 74 -WSKTSGEQRGILLSKLFDLIERDKLLLAAIETLDSGKPYHSNSLADLEQILQLTRYYAG 132
W + + +RG L+ +L DL+E ++ LA IE LDSG Y + +Q RY+AG
Sbjct: 497 EWGRMNARERGRLMYRLADLLEENQEELATIEALDSGAVYTLALKTHIGMSVQTFRYFAG 556
Query: 133 GADKFTGGEYIPLNQDK----YAYTMKVPYGVVAQIVPWNYPLAMASWKIQSCLAAGNTI 188
DK G IP+NQ + +T K P GV A I+PWNYPL M +WK +CLAAGNT+
Sbjct: 557 WCDKIQGST-IPINQARPNRNLTFTKKEPLGVCAIIIPWNYPLMMLAWKSAACLAAGNTL 615
Query: 189 VIKPAENTSLSLLYFAQLVKEAGFPPGVLNILPGYGSVTGTAMASHTDIDKIAFTGSTAV 248
V+KPA+ T L+ L FA+L +AGFP GV+NI+PG G + G ++ H DI K+ FTGST +
Sbjct: 616 VLKPAQVTPLTALKFAELSVKAGFPKGVINIIPGSGGIAGQRLSEHPDIRKLGFTGSTPI 675
Query: 249 GQKVMSLAAQSNLKAVTLECGGKSPCLIFADANLDEAIPWVAGGIFYNSGQNCTANSRIY 308
G+++M A SNLK V+LE GGKSP +IF D LD+A+ G +F+N G+NC A R++
Sbjct: 676 GKQIMKSCAVSNLKKVSLELGGKSPLIIFNDCELDKAVRMGMGAVFFNKGENCIAAGRLF 735
Query: 309 VHEDIYEEFLTKFEEYAKSNWKFGAKFDPFDKDCTLGPVISKVQYDRIQSYVEHGKASEK 368
V E I++EF+T+ E K K G DP D+ GP K +++ Y E G
Sbjct: 736 VEESIHDEFVTRVVEEIK-KMKIG---DPLDRSTDHGPQNHKAHLEKLLQYCETGVKEGA 791
Query: 369 LGFKEFAEYPSKGYFIPPTIFSDVPNSSKLSQEEIFGPVGVVASFST--YEEAIKLANDS 426
+ G+F+ PT+F+DV + L++EE FGP+ V++ F + ++ AN +
Sbjct: 792 TLVYGGRQVQRPGFFMEPTVFTDVEDYMYLAKEESFGPIMVISKFQNGDIDGVLQRANST 851
Query: 427 SYGLASCVFSENARTTAQFARDIRAGTVWINSSNDEEISVPFGGFKMSGIGRELGRNGVD 486
YGLAS VF+ + + + AGTV+IN+ N +++ PFGG K SG G++LG V+
Sbjct: 852 EYGLASGVFTRDINKAMYVSEKLEAGTVFINTYNKTDVAAPFGGVKQSGFGKDLGI--VN 909
Query: 487 SYLQT-----------KAVHVN 497
++L+T KA H+N
Sbjct: 910 AFLRTLNRRIHCSNVSKAPHIN 931
>Hs21614513 [F] KOG2452 Formyltetrahydrofolate dehydrogenase
Length = 902
Score = 362 bits (929), Expect = e-100
Identities = 198/487 (40%), Positives = 284/487 (57%), Gaps = 12/487 (2%)
Query: 15 TYEQPLGLFINNEFVKSSDGKKIESINPSTEESIVSFFAASEKDVNSAVTAARDAFENN- 73
T P LFI EFV + K E+INP+ I A DV+ AV AA+DAFEN
Sbjct: 417 TVRMPHQLFIGGEFVDAEGAKTSETINPTDGSVICQVSLAQVTDVDKAVAAAKDAFENGR 476
Query: 74 WSKTSGEQRGILLSKLFDLIERDKLLLAAIETLDSGKPYHSNSLADLEQILQLTRYYAGG 133
W K S RG L+ +L DL+E+ + LA IE LD+G Y + +Q RY+AG
Sbjct: 477 WGKISARDRGRLMYRLADLMEQHQEELATIEALDAGAVYTLALKTHVGMSIQTFRYFAGW 536
Query: 134 ADKFTGGEYIPLNQDK----YAYTMKVPYGVVAQIVPWNYPLAMASWKIQSCLAAGNTIV 189
DK G IP+NQ + T K P GV I+PWNYPL M SWK +CLAAGNT+V
Sbjct: 537 CDKIQGST-IPINQARPNRNLTLTRKEPVGVCGIIIPWNYPLMMLSWKTAACLAAGNTVV 595
Query: 190 IKPAENTSLSLLYFAQLVKEAGFPPGVLNILPGYGSVTGTAMASHTDIDKIAFTGSTAVG 249
IKPA+ T L+ L FA+L +AG P GV+N+LPG GS+ G ++ H D+ KI FTGST VG
Sbjct: 596 IKPAQVTPLTALKFAELTLKAGIPKGVVNVLPGSGSLVGQRLSDHPDVRKIGFTGSTEVG 655
Query: 250 QKVMSLAAQSNLKAVTLECGGKSPCLIFADANLDEAIPWVAGGIFYNSGQNCTANSRIYV 309
+ +M A SN+K V+LE GGKSP +IFAD +L++A+ +F+N G+NC A R++V
Sbjct: 656 KHIMKSCAISNVKKVSLELGGKSPLIIFADCDLNKAVQMGMSSVFFNKGENCIAAGRLFV 715
Query: 310 HEDIYEEFLTKFEEYAKSNWKFGAKFDPFDKDCTLGPVISKVQYDRIQSYVEHGKASEKL 369
+ I++EF+ + E + K G +P D+D GP ++ Y +HG
Sbjct: 716 EDSIHDEFVRRVVEEVR-KMKVG---NPLDRDTDHGPQNHHAHLVKLMEYCQHGVKEGAT 771
Query: 370 GFKEFAEYPSKGYFIPPTIFSDVPNSSKLSQEEIFGPVGVVASFS--TYEEAIKLANDSS 427
+ P G+F PT+F+DV + +++EE FGPV +++ F+ + + AN +
Sbjct: 772 LVCGGNQVPRPGFFFEPTVFTDVEDHMFIAKEESFGPVMIISRFADGDLDAVLSRANATE 831
Query: 428 YGLASCVFSENARTTAQFARDIRAGTVWINSSNDEEISVPFGGFKMSGIGRELGRNGVDS 487
+GLAS VF+ + + ++AGTV++N+ N +++ PFGGFK SG G++LG ++
Sbjct: 832 FGLASGVFTRDINKALYVSDKLQAGTVFVNTYNKTDVAAPFGGFKQSGFGKDLGEAALNE 891
Query: 488 YLQTKAV 494
YL+ K V
Sbjct: 892 YLRVKTV 898
>HsM7110595 [F] KOG2452 Formyltetrahydrofolate dehydrogenase
Length = 902
Score = 355 bits (912), Expect = 7e-98
Identities = 195/487 (40%), Positives = 283/487 (58%), Gaps = 12/487 (2%)
Query: 15 TYEQPLGLFINNEFVKSSDGKKIESINPSTEESIVSFFAASEKDVNSAVTAARDAFENN- 73
T P LFI EFV + K E+INP+ I A DV+ AV AA+ AFEN
Sbjct: 417 TVRMPHQLFIGGEFVDAEGAKTSETINPTDGSVICQVSLAQVTDVDKAVAAAKGAFENGR 476
Query: 74 WSKTSGEQRGILLSKLFDLIERDKLLLAAIETLDSGKPYHSNSLADLEQILQLTRYYAGG 133
W K S RG L+ +L DL+E+ + LA IE LD+G Y + +Q RY+AG
Sbjct: 477 WGKISARDRGRLMYRLADLMEQHQEELATIEALDAGAVYTLALKTHVGMSIQTFRYFAGW 536
Query: 134 ADKFTGGEYIPLNQDK----YAYTMKVPYGVVAQIVPWNYPLAMASWKIQSCLAAGNTIV 189
DK G IP+NQ + T K P GV I+PWNYPL M SWK +CLAAGNT+V
Sbjct: 537 CDKIQGST-IPINQARPNRNLTLTRKEPVGVCGIIIPWNYPLMMLSWKTAACLAAGNTVV 595
Query: 190 IKPAENTSLSLLYFAQLVKEAGFPPGVLNILPGYGSVTGTAMASHTDIDKIAFTGSTAVG 249
IKPA+ T L+ L FA+L +AG P GV+N+LPG GS+ G ++ H D+ KI FTGST VG
Sbjct: 596 IKPAQVTPLTALKFAELTLKAGIPKGVVNVLPGSGSLVGQRLSDHPDVRKIGFTGSTEVG 655
Query: 250 QKVMSLAAQSNLKAVTLECGGKSPCLIFADANLDEAIPWVAGGIFYNSGQNCTANSRIYV 309
+ +M A SN+K V+LE GG+SP +IFAD +L++A+ +F++ G+NC A R++V
Sbjct: 656 KHIMKSCAISNVKKVSLELGGESPFIIFADCDLNKAVQMGMSSVFFSKGENCIAAGRLFV 715
Query: 310 HEDIYEEFLTKFEEYAKSNWKFGAKFDPFDKDCTLGPVISKVQYDRIQSYVEHGKASEKL 369
+ I++EF+ + E + K G +P D+D GP ++ Y +HG
Sbjct: 716 EDSIHDEFVRRVVEEVR-KMKVG---NPLDRDTDHGPQNHHAHLVKLMEYCQHGVKEGAT 771
Query: 370 GFKEFAEYPSKGYFIPPTIFSDVPNSSKLSQEEIFGPVGVVASFS--TYEEAIKLANDSS 427
+ P G+F PT+F+DV + +++EE FGPV +++ F+ + + AN +
Sbjct: 772 LVCGGNQVPRPGFFFEPTVFTDVEDHMFIAKEESFGPVMIISRFADGDLDAVLSRANATE 831
Query: 428 YGLASCVFSENARTTAQFARDIRAGTVWINSSNDEEISVPFGGFKMSGIGRELGRNGVDS 487
+GLAS VF+ + + ++AGTV++N+ N +++ PFGGFK SG G++LG ++
Sbjct: 832 FGLASGVFTRDINKALYVSDKLQAGTVFVNTYNKTDVAAPFGGFKQSGFGKDLGEAALNE 891
Query: 488 YLQTKAV 494
YL+ K V
Sbjct: 892 YLRVKTV 898
>At3g48170 [C] KOG2450 Aldehyde dehydrogenase
Length = 503
Score = 353 bits (905), Expect = 4e-97
Identities = 201/482 (41%), Positives = 283/482 (58%), Gaps = 15/482 (3%)
Query: 22 LFINNEFVKSSDGKKIESINPSTEESIVSFFAASEKDVNSAVTAARDAFENN----WSKT 77
LFI ++ + K + +NP+TE+ I AA+ +DV AV AAR AF N W++
Sbjct: 10 LFIGGQWTEPVLRKTLPVVNPATEDIIGYIPAATSEDVELAVEAARKAFTRNNGKDWARA 69
Query: 78 SGEQRGILLSKLFDLIERDKLLLAAIETLDSGKPYHSNSLADLEQILQLTRYYAGGADKF 137
+G R L + + K LA +E +D GKP + D++ + YYA A+
Sbjct: 70 TGAVRAKYLRAIAAKVIERKSELANLEAIDCGKPL-DEAAWDMDDVAGCFEYYADLAEGL 128
Query: 138 TGGEYIPLN--QDKY-AYTMKVPYGVVAQIVPWNYPLAMASWKIQSCLAAGNTIVIKPAE 194
+ PL+ D + Y +K P GVV I PWNYPL MA WK+ LAAG T ++KP+E
Sbjct: 129 DAKQKTPLSLPMDTFKGYILKEPIGVVGMITPWNYPLLMAVWKVAPSLAAGCTAILKPSE 188
Query: 195 NTSLSLLYFAQLVKEAGFPPGVLNILPGYGSVTGTAMASHTDIDKIAFTGSTAVGQKVMS 254
SL+ L A + +E G PPGVLNIL G G+ G +ASH +DKI FTGST G +M+
Sbjct: 189 LASLTCLELADICREVGLPPGVLNILTGLGTEAGAPLASHPHVDKIVFTGSTTTGSSIMT 248
Query: 255 LAAQSNLKAVTLECGGKSPCLIFADANLDEAIPWVAGGIFYNSGQNCTANSRIYVHEDIY 314
AA+ +K V+LE GGKSP ++F D ++D+A+ W G F+ +GQ C+A SR+ VHE I
Sbjct: 249 SAAKL-VKPVSLELGGKSPIIVFDDVDIDKAVEWTMFGCFWTNGQICSATSRLLVHERIA 307
Query: 315 EEFLTKFEEYAKSNWKFGAKFDPFDKDCTLGPVISKVQYDRIQSYVEHGK--ASEKLGFK 372
+EFL K ++ K N K DPF++ C LGPV+SK QY+R+ +V + + + L
Sbjct: 308 DEFLDKLVKWTK-NIKIS---DPFEEGCRLGPVVSKGQYERVLKFVSNARNEGATVLCGG 363
Query: 373 EFAEYPSKGYFIPPTIFSDVPNSSKLSQEEIFGPVGVVASFSTYEEAIKLANDSSYGLAS 432
E+ KGYF+ P I S+V S ++ +EE+FGP V +FST +EAI+LANDS YGLA
Sbjct: 364 VRPEHLKKGYFVEPAIVSNVTTSMEIWREEVFGPALCVKTFSTEDEAIQLANDSQYGLAG 423
Query: 433 CVFSENARTTAQFARDIRAGTVWINSSNDEEISVPFGGFKMSGIGRELGRNGVDSYLQTK 492
V S + + ++ +AG VW+N S P+GG K SG GRELG G+++YL K
Sbjct: 424 AVLSNDLERCDRVSKAFQAGIVWVNCSQPCFCQAPWGGTKRSGFGRELGEWGLENYLSVK 483
Query: 493 AV 494
V
Sbjct: 484 QV 485
>At1g74920 [C] KOG2450 Aldehyde dehydrogenase
Length = 481
Score = 337 bits (865), Expect = 2e-92
Identities = 197/486 (40%), Positives = 275/486 (56%), Gaps = 43/486 (8%)
Query: 22 LFINNEFVKSSDGKKIESINPSTEESIV------SFFAASEKDVNSAVTAARDAFENN-- 73
LFI+ E+ + K+I +NP+TEE + AA+ +DV+ AV AAR A N
Sbjct: 10 LFIDGEWREPILKKRIPIVNPATEEDLYVLDEIGDIPAATTEDVDVAVNAARRALSRNKG 69
Query: 74 --WSKTSGEQRGILLSKLFDLIERDKLLLAAIETLDSGKPYHSNSLADLEQILQLTRYYA 131
W+K G R L + + K LA +E LD GKP ++ D++ + +YA
Sbjct: 70 KDWAKAPGAVRAKYLRAIAAKVNERKTDLAKLEALDCGKPL-DEAVWDMDDVAGCFEFYA 128
Query: 132 GGADKFTGGEYIPLN---QDKYAYTMKVPYGVVAQIVPWNYPLAMASWKIQSCLAAGNTI 188
A+ + P++ + +Y +K P GVV I PWNYPL MA WK+ LAAG T
Sbjct: 129 DLAEGLDAKQKAPVSLPMESFKSYVLKQPLGVVGLITPWNYPLLMAVWKVAPSLAAGCTA 188
Query: 189 VIKPAENTSLSLLYFAQLVKEAGFPPGVLNILPGYGSVTGTAMASHTDIDKIAFTGSTAV 248
++KP+E S++ L A + +E G PPGVLN+L G+GS G +ASH +DKIAFTGS A
Sbjct: 189 ILKPSELASVTCLELADICREVGLPPGVLNVLTGFGSEAGAPLASHPGVDKIAFTGSFAT 248
Query: 249 GQKVMSLAAQSNLKAVTLECGGKSPCLIFADANLDEAIPWVAGGIFYNSGQNCTANSRIY 308
G KVM+ AAQ +K V++E GGKSP ++F D +LD+A W G F+ +GQ C+A SR+
Sbjct: 249 GSKVMTAAAQL-VKPVSMELGGKSPLIVFDDVDLDKAAEWALFGCFWTNGQICSATSRLL 307
Query: 309 VHEDIYEEFLTKFEEYAKSNWKFGAKFDPFDKDCTLGPVISKVQYDRIQSYVEHGKASEK 368
VHE I EF+ K +++K N K DP ++ C LGPV+SK
Sbjct: 308 VHESIASEFIEKLVKWSK-NIKIS---DPMEEGCRLGPVVSK------------------ 345
Query: 369 LGFKEFAEYPSKGYFIPPTIFSDVPNSSKLSQEEIFGPVGVVASFSTYEEAIKLANDSSY 428
++ KG+FI PTI +DV S ++ +EE+FGPV V +F++ +EAI+LANDS Y
Sbjct: 346 ------GQHLEKGFFIEPTIITDVTTSMQIWREEVFGPVLCVKTFASEDEAIELANDSHY 399
Query: 429 GLASCVFSENARTTAQFARDIRAGTVWINSSNDEEISVPFGGFKMSGIGRELGRNGVDSY 488
GL + V S + + + AG VWIN S P+GG K SG GRELG G+D+Y
Sbjct: 400 GLGAAVISNDTERCDRISEAFEAGIVWINCSQPCFTQAPWGGVKRSGFGRELGEWGLDNY 459
Query: 489 LQTKAV 494
L K V
Sbjct: 460 LSVKQV 465
>SPCC550.10 [C] KOG2450 Aldehyde dehydrogenase
Length = 500
Score = 337 bits (863), Expect = 3e-92
Identities = 200/479 (41%), Positives = 286/479 (58%), Gaps = 12/479 (2%)
Query: 22 LFINNEFVKSSD--GKKIESINPSTEESIVSFFAASEKDVNSAVTAARDAFENN-WSKTS 78
LFI+ +FV + K I INP+TEE I + AS KDV+SAV A + F + W+K
Sbjct: 23 LFIDGKFVSPIEPAAKPIPLINPATEEIIGTCANASAKDVDSAVENAYNTFRSGIWAKWP 82
Query: 79 GEQRGILLSKLFDLIERDKLLLAAIETLDSGKPYHSNSLADLEQILQLTRYYAGGADKFT 138
G+QRG++L K+ ++ + LLA I+T++ GKP +L D++ + YYA A+
Sbjct: 83 GKQRGLVLRKIAKMMREKRELLAGIDTINCGKPT-PYALFDIDSCADMFEYYAEVAETDN 141
Query: 139 GGEYIPL--NQDKYAYTMKVPYGVVAQIVPWNYPLAMASWKIQSCLAAGNTIVIKPAENT 196
+PL N A+ + P GV+ I PWN+PL MA WK+ +A+GN +V+KP+E
Sbjct: 142 PTVKVPLPNNPGFCAFEKRFPRGVIGVITPWNFPLKMALWKLVPAIASGNCVVLKPSELA 201
Query: 197 SLSLLYFAQLVKEAGFPPGVLNILPGYGSVTGTAMASHTDIDKIAFTGSTAVGQKVMSLA 256
S L FA + KEAG P GVLN++ G G +G A++ H I +AFTGS A G+K+M A
Sbjct: 202 PWSCLEFALICKEAGLPDGVLNVIIGSGKESGAALSCHPKIAYLAFTGSLATGKKIMHAA 261
Query: 257 AQSNLKAVTLECGGKSPCLIFADANLDEAIPWVAGGIFYNSGQNCTANSRIYVHEDIYEE 316
A+ N+ +TLE GGKSP +I DA+L AIP A IF+N G+ CTA SR+ VHE + +E
Sbjct: 262 AE-NIVPLTLELGGKSPLIICEDADLSLAIPSAAFAIFFNQGEACTAASRLIVHESVADE 320
Query: 317 FLTKFEEYAKSNWKFGAKFDPFDKDCTLGPVISKVQYDRIQSYVEHG-KASEKLGFKEFA 375
L A + G DP TLGPV+SK Q+++I SY++ K
Sbjct: 321 VLGGLVSEA-NKLIIGNGLDP---QVTLGPVVSKTQFEKIVSYIQSAINEGCKCVVGGLP 376
Query: 376 EYPSKGYFIPPTIFSDVPNSSKLSQEEIFGPVGVVASFSTYEEAIKLANDSSYGLASCVF 435
KGYFIPPT+F++V +K+ +EEIFGPV V +F T EEA++LANDS YGL S VF
Sbjct: 377 RSEQKGYFIPPTVFTNVQTHNKIWREEIFGPVLAVKTFHTNEEALELANDSEYGLGSGVF 436
Query: 436 SENARTTAQFARDIRAGTVWINSSNDEEISVPFGGFKMSGIGRELGRNGVDSYLQTKAV 494
S N +T F+ +I AG +N+ + +P+ G+K SG+G L ++G + Y++ K +
Sbjct: 437 STNPKTLEFFSNNIEAGMCSLNNYHVVTHELPWIGWKHSGLGVGLSKHGYNEYMRLKQI 495
>CE05817 [F] KOG2452 Formyltetrahydrofolate dehydrogenase
Length = 887
Score = 323 bits (827), Expect = 5e-88
Identities = 183/503 (36%), Positives = 288/503 (56%), Gaps = 39/503 (7%)
Query: 4 YETVNIPQLNITYEQPLGLFINNEFVKSSDGKKIESINPSTEESIVSFFAASEKDVNSAV 63
Y+ + + N+ + P FI+ +FV SSDG+ ++INP+TE+ I A+ DV+ AV
Sbjct: 412 YDPIVLNVNNMELKFPHDQFIDGKFVGSSDGRTFKTINPATEKPICELPLATVADVDRAV 471
Query: 64 TAARDAFENN-WSKTSGEQRGILLSKLFDLIERDKLLLAAIETLDSGKPYHSNSLADLEQ 122
AA+ AFE W + S +RG L KL +L+E K LA +E+LD+G Y +
Sbjct: 472 RAAKKAFERGEWRQMSARERGKRLYKLAELMEEHKEELATLESLDAGAVYTLALKTHVGM 531
Query: 123 ILQLTRYYAGGADKFTGGEYIPLNQDK----YAYTMKVPYGVVAQIVPWNYPLAMASWKI 178
+ + RY+AG DK G + IP++ + T++ P GVV I PWNYPL M SWK+
Sbjct: 532 SIDVWRYFAGWCDKIQG-KTIPISNARPNKNLCLTLREPIGVVGLITPWNYPLMMLSWKM 590
Query: 179 QSCLAAGNTIVIKPAENTSLSLLYFAQLVKEAGFPPGVLNILPGYGSVTGTAMASHTDID 238
+CLAA +I+ + GV+NI+ G GS+ G + +H D+
Sbjct: 591 AACLAAAKIKLIEIS---------------------GVINIVTGSGSLVGNRLTAHPDVR 629
Query: 239 KIAFTGSTAVGQKVMSLAAQSNLKAVTLECGGKSPCLIFADANLDEAIPWVAGGIFYNSG 298
KI FTGST +G VM A+SN+K V+LE GGKSP +IFADA+L++A+ G +F+N G
Sbjct: 630 KIGFTGSTEIGATVMESCAKSNIKKVSLELGGKSPLIIFADADLEKAVKQACGAVFFNKG 689
Query: 299 QNCTANSRIYVHEDIYEEFLTKFEEYAKSNWKFGAKFDPFDKDCTLGPVISKVQYDRIQS 358
+NC A R+++ + I+++F+ K E AK ++ G DP D+ GP +++
Sbjct: 690 ENCIAAGRVFIAKSIHDDFVKKLVEEAK-QYQIG---DPLDRSTAHGPQNHLAHLNKLVE 745
Query: 359 YVEH---GKASEKLGFKEFAEYPSKGYFIPPTIFSDVPNSSKLSQEEIFGPVGVVASF-- 413
YVE G A ++G K +G + PPTI S++ + + + EE FGP+ V+SF
Sbjct: 746 YVEKAVAGGAKVEVGGKRLER---EGLYFPPTILSNIDDENFAASEESFGPIMCVSSFDD 802
Query: 414 STYEEAIKLANDSSYGLASCVFSENARTTAQFARDIRAGTVWINSSNDEEISVPFGGFKM 473
E+ ++ AND+ +GLA+ VF+ ++ + + A + AGTV++N+ +++ PFGGFK
Sbjct: 803 DDIEDVLRRANDTEFGLAAGVFTRDSSKSLRVAEALHAGTVFVNTYQKTDVAAPFGGFKQ 862
Query: 474 SGIGRELGRNGVDSYLQTKAVHV 496
SG G+++G ++ YL TK + +
Sbjct: 863 SGFGKDMGEEALNEYLVTKTITI 885
>Hs12007648 [C] KOG2450 Aldehyde dehydrogenase
Length = 487
Score = 300 bits (769), Expect = 3e-81
Identities = 176/481 (36%), Positives = 268/481 (55%), Gaps = 15/481 (3%)
Query: 23 FINNEFVKSSDGKKIESINPSTEESIVSFFAASEKDVNSAVTAARDAFENNWSKTSGEQR 82
FI+ +F+ S I+S +PST E + + ++ +AV AAR+AF + WS S ++R
Sbjct: 13 FIDGKFLPCSS--YIDSYDPSTGEVYCRVPNSGKDEIEAAVKAAREAFPS-WSSRSPQER 69
Query: 83 GILLSKLFDLIERDKLLLAAIETLDSGKPYHSNSLADLEQILQLTRYYAGGADKFTGGEY 142
+L+++ DL+E+ A E+ D GK D+ + +Q R++A + T
Sbjct: 70 SRVLNQVADLLEQSLEEFAQAESKDQGKTLALARTMDIPRSVQNFRFFASSSLHHTSECT 129
Query: 143 IPLNQDKYAYTMKVPYGVVAQIVPWNYPLAMASWKIQSCLAAGNTIVIKPAENTSLSLLY 202
+ YT++ P GV I PWN PL + +WKI +AAGNT++ KP+E TS++
Sbjct: 130 QMDHLGCMHYTVRAPVGVAGLISPWNLPLYLLTWKIAPAMAAGNTVIAKPSELTSVTAWM 189
Query: 203 FAQLVKEAGFPPGVLNILPGYGSVTGTAMASHTDIDKIAFTGSTAVGQKVMSLAAQSNLK 262
+L+ +AG PPGV+NI+ G G G A+ SH ++ I+FTGS +++ L+A + K
Sbjct: 190 LCKLLDKAGVPPGVVNIVFGTGPRVGEALVSHPEVPLISFTGSQPTAERITQLSA-PHCK 248
Query: 263 AVTLECGGKSPCLIFADANLDEAIPWVAGGIFYNSGQNCTANSRIYVHEDIYEEFLTKFE 322
++LE GGK+P +IF DANLDE IP F N G+ C SRI+V + IY EFL +F
Sbjct: 249 KLSLELGGKNPAIIFEDANLDECIPATVRSSFANQGEICLCTSRIFVQKSIYSEFLKRFV 308
Query: 323 EYAKSNWKFGAKFDPFDKDCTLGPVISKVQYDRIQSYVEHGKA-------SEKLGFKEFA 375
E A WK G DP ++G +ISK ++++SYV+ A E +
Sbjct: 309 E-ATRKWKVGIPSDPL---VSIGALISKAHLEKVRSYVKRALAEGAQIWCGEGVDKLSLP 364
Query: 376 EYPSKGYFIPPTIFSDVPNSSKLSQEEIFGPVGVVASFSTYEEAIKLANDSSYGLASCVF 435
GYF+ PT+ +D+ + S EEIFGPV V F + EE I+ AN+ YGLA+ V+
Sbjct: 365 ARNQAGYFMLPTVITDIKDESCCMTEEIFGPVTCVVPFDSEEEVIERANNVKYGLAATVW 424
Query: 436 SENARTTAQFARDIRAGTVWINSSNDEEISVPFGGFKMSGIGRELGRNGVDSYLQTKAVH 495
S N + A+ +++G VW N E+++PFGG K SGIGRE ++ D + + K +
Sbjct: 425 SSNVGRVHRVAKKLQSGLVWTNCWLIRELNLPFGGMKSSGIGREGAKDSYDFFTEIKTIT 484
Query: 496 V 496
V
Sbjct: 485 V 485
>CE06980 [C] KOG2450 Aldehyde dehydrogenase
Length = 506
Score = 288 bits (738), Expect = 1e-77
Identities = 179/487 (36%), Positives = 274/487 (55%), Gaps = 16/487 (3%)
Query: 19 PLGLFINNEFVKSSDGKKIESINPSTEESIVSFFAASEKDVNSAVTAARDAFENNWSKTS 78
PL FI NEF +S K ++S+NPST + + + ++V+ AV AA++AF+ W KT+
Sbjct: 27 PLTNFIGNEFARSE--KLMDSVNPSTGKPWIKIPDGTAREVDQAVEAAKEAFKT-WKKTT 83
Query: 79 GEQRGILLSKLFDLIERDKLLLAAIETLDSGKPYHSNSLADLEQILQLTRYYAGGA-DKF 137
+QR LL+K+ +LIE +A +E+ D GKP + D+ + +Q R +A A
Sbjct: 84 VQQRSALLNKVANLIEEFNDDIAILESRDQGKPIGLAKVMDIPRCVQNFRDFANAALYSL 143
Query: 138 TGGEYIPLNQDKYA-YTMKVPYGVVAQIVPWNYPLAMASWKIQSCLAAGNTIVIKPAENT 196
+ + K+ Y P GV I PWN PL + S+K+ L AGNT+V KP+E T
Sbjct: 144 STSTILEQPTGKFVNYVKNDPVGVAGLISPWNLPLYLLSFKLAPALVAGNTVVCKPSEMT 203
Query: 197 SLSLLYFAQLVKEAGFPPGVLNILPGYGSVTGTAMASHTDIDKIAFTGSTAVGQKVMSLA 256
S++ K GFPPGV+N++ G G G + H D+ I+FTGST +G+K+
Sbjct: 204 SVTAWVLMHAFKLVGFPPGVVNMVIGEGKSAGQRLVDHVDVPLISFTGSTVIGKKIQEDG 263
Query: 257 AQSNLKAVTLECGGKSPCLIFADANLDEAIPWVAGGIFYNSGQNCTANSRIYVHEDIYEE 316
A+ N K V+LE GGK+P +++++ + I +A F N G+ C SR++V + I+ +
Sbjct: 264 AKLN-KKVSLEMGGKNPGIVYSNYRKSD-IASIARSSFLNQGEICLCTSRLFVQKPIFAD 321
Query: 317 FLTKFEEYAKSNWKFGAKFDPFDKDCTLGPVISKVQYDRIQSYVEHGK--ASEKL--GFK 372
F+ + E AK KF DP + +G + SKV Y++++SY+E K ++ L G
Sbjct: 322 FVKSYVEEAK---KFTVG-DPTTQ-VQIGAMNSKVHYEKVKSYIELAKKEGADILCGGVT 376
Query: 373 EFAEYPSKGYFIPPTIFSDVPNSSKLSQEEIFGPVGVVASFSTYEEAIKLANDSSYGLAS 432
GYFI PT+ + ++SK+ +EIFGPV + F T EE I+ AN + YGL++
Sbjct: 377 TIQNGCENGYFITPTVIVGLHDASKVMTDEIFGPVVCITPFDTAEEVIERANSTPYGLSA 436
Query: 433 CVFSENARTTAQFARDIRAGTVWINSSNDEEISVPFGGFKMSGIGRELGRNGVDSYLQTK 492
V+S ++ A ++RAGTVW N+ ++S+PFGG K SG GRE + + Y K
Sbjct: 437 TVWSSDSDELLNTANELRAGTVWCNTWLARDLSMPFGGCKQSGNGREGLHDSLHFYSDAK 496
Query: 493 AVHVNIA 499
V VNIA
Sbjct: 497 TVCVNIA 503
>At1g79440 [C] KOG2451 Aldehyde dehydrogenase
Length = 528
Score = 280 bits (715), Expect = 5e-75
Identities = 165/471 (35%), Positives = 257/471 (54%), Gaps = 7/471 (1%)
Query: 24 INNEFVKSSDGKKIESINPSTEESIVSFFAASEKDVNSAVTAARDAFENNWSKTSGEQRG 83
I +++ S D K I+ NP+T E I K+ N A+ ++ +AF +WS+ + +R
Sbjct: 57 IGGKWLDSYDNKTIKVNNPATGEIIADVACMGTKETNDAIASSYEAF-TSWSRLTAGERS 115
Query: 84 ILLSKLFDLIERDKLLLAAIETLDSGKPYHSNSLADLEQILQLTRYYAGGADKFTGGEYI 143
+L + +DL+ K L + TL+ GKP ++ ++ YYA A + G
Sbjct: 116 KVLRRWYDLLIAHKEELGQLITLEQGKPL-KEAIGEVAYGASFIEYYAEEAKRVYGDIIP 174
Query: 144 PLNQDKYAYTMKVPYGVVAQIVPWNYPLAMASWKIQSCLAAGNTIVIKPAENTSLSLLYF 203
P D+ +K P GVV I PWN+PLAM + K+ LA+G T+V+KP+E T L+ L
Sbjct: 175 PNLSDRRLLVLKQPVGVVGAITPWNFPLAMITRKVGPALASGCTVVVKPSELTPLTALAA 234
Query: 204 AQLVKEAGFPPGVLNILPGYGSVTGTAMASHTDIDKIAFTGSTAVGQKVMSLAAQSNLKA 263
A+L +AG PPG LN++ G G A+ + + KI FTGSTAVG+K+M+ AA + +K
Sbjct: 235 AELALQAGVPPGALNVVMGNAPEIGDALLTSPQVRKITFTGSTAVGKKLMAAAAPT-VKK 293
Query: 264 VTLECGGKSPCLIFADANLDEAIPWVAGGIFYNSGQNCTANSRIYVHEDIYEEFLTKFEE 323
V+LE GG +P ++F DA+LD A+ F NSGQ C +R+ V + IY++F F E
Sbjct: 294 VSLELGGNAPSIVFDDADLDVAVKGTLAAKFRNSGQTCVCANRVLVQDGIYDKFAEAFSE 353
Query: 324 YAKSNWKFGAKFDPFDKDCTLGPVISKVQYDRIQSYVEHGKASEKLGFKEFAEYPSKGYF 383
A + G D F T GP+I+ +++++V+ + + F
Sbjct: 354 -AVQKLEVG---DGFRDGTTQGPLINDAAVQKVETFVQDAVSKGAKIIIGGKRHSLGMTF 409
Query: 384 IPPTIFSDVPNSSKLSQEEIFGPVGVVASFSTYEEAIKLANDSSYGLASCVFSENARTTA 443
PT+ DV ++ +S+EEIFGPV + F T E+AI++AND+ GLA+ +F+ + + +
Sbjct: 410 YEPTVIRDVSDNMIMSKEEIFGPVAPLIRFKTEEDAIRIANDTIAGLAAYIFTNSVQRSW 469
Query: 444 QFARDIRAGTVWINSSNDEEISVPFGGFKMSGIGRELGRNGVDSYLQTKAV 494
+ + G V +N PFGG K SG+GRE + G+D YL+ K V
Sbjct: 470 RVFEALEYGLVGVNEGLISTEVAPFGGVKQSGLGREGSKYGMDEYLEIKYV 520
>Hs4502047 [C] KOG2450 Aldehyde dehydrogenase
Length = 493
Score = 279 bits (713), Expect = 8e-75
Identities = 165/467 (35%), Positives = 261/467 (55%), Gaps = 15/467 (3%)
Query: 38 ESINPSTEESIVSFFAASEKDVNSAVTAARDAFENNWSKTSGEQRGILLSKLFDLIERDK 97
++ P+T I +F + EK+VN AV A+ AF+ WS+ SG +R +L + +I +
Sbjct: 29 KAFEPATGRVIATFTCSGEKEVNLAVQNAKAAFKI-WSQKSGMERCRILLEAARIIRERE 87
Query: 98 LLLAAIETLDSGKPYHSNSLADLEQILQLTRYYAGGADKFTGGEYIPLNQDKYAYTMKVP 157
+A +E +++GK L D++ Q YYAG A G E+I L + YT + P
Sbjct: 88 DEIATMECINNGKSIFEARL-DIDISWQCLEYYAGLAASMAG-EHIQLPGGSFGYTRREP 145
Query: 158 YGVVAQIVPWNYPLAMASWKIQSCLAAGNTIVIKPAENTSLSLLYFAQLVKEAGFPPGVL 217
GV I WNYP +ASWK LA GN +V KP+ T +S L A++ EAG PPG+
Sbjct: 146 LGVCVGIGAWNYPFQIASWKSAPALACGNAMVFKPSPFTPVSALLLAEIYSEAGVPPGLF 205
Query: 218 NILPGYGSVTGTAMASHTDIDKIAFTGSTAVGQKVMSLAAQSNLKAVTLECGGKSPCLIF 277
N++ G G+ TG + H D+ K++FTGS G K+M ++A+ +K VTLE GGKSP +IF
Sbjct: 206 NVVQG-GAATGQFLCQHPDVAKVSFTGSVPTGMKIMEMSAKG-IKPVTLELGGKSPLIIF 263
Query: 278 ADANLDEAIPWVAGGIFYNSGQNCTANSRIYVHEDIYEEFLTKFEEYAKSNWKFGAKFDP 337
+D +++ A+ F GQ C +R++V ++I ++F EE K + DP
Sbjct: 264 SDCDMNNAVKGALMANFLTQGQVCCNGTRVFVQKEILDKFT---EEVVKQTQRIKIG-DP 319
Query: 338 FDKDCTLGPVISKVQYDRIQSYVEHGK---ASEKLGFKEFAEYPSK---GYFIPPTIFSD 391
+D +GP+I++ +R+ +V+ K A G + K GY++ P + ++
Sbjct: 320 LLEDTRMGPLINRPHLERVLGFVKVAKEQGAKVLCGGDIYVPEDPKLKDGYYMRPCVLTN 379
Query: 392 VPNSSKLSQEEIFGPVGVVASFSTYEEAIKLANDSSYGLASCVFSENARTTAQFARDIRA 451
+ +EEIFGPV + SF T E ++ AND+++GLA+ VF+ + + + +++A
Sbjct: 380 CRDDMTCVKEEIFGPVMSILSFDTEAEVLERANDTTFGLAAGVFTRDIQRAHRVVAELQA 439
Query: 452 GTVWINSSNDEEISVPFGGFKMSGIGRELGRNGVDSYLQTKAVHVNI 498
GT +IN+ N + +PFGG+K SG GRE GR ++ Y Q K V V +
Sbjct: 440 GTCFINNYNVSPVELPFGGYKKSGFGRENGRVTIEYYSQLKTVCVEM 486
>7298784 [F] KOG2452 Formyltetrahydrofolate dehydrogenase
Length = 816
Score = 275 bits (703), Expect = 1e-73
Identities = 146/349 (41%), Positives = 207/349 (58%), Gaps = 9/349 (2%)
Query: 19 PLGLFINNEFVKSSDGKKIESINPSTEESIVSFFAASEKDVNSAVTAARDAFENNWSKTS 78
P LFIN EFV + + +E +NP+ EE + AS DV+ AV AA AF +W + +
Sbjct: 428 PTQLFINGEFVDAEAQRTLEIVNPTNEEVLCKVACASATDVDKAVRAAHSAFYGSWRQIT 487
Query: 79 GEQRGILLSKLFDLIERDKLLLAAIETLDSGKPYHSNSLADLEQILQLTRYYAGGADKFT 138
QRG L+ L DL+ER+K LA IE++DSG Y + ++ RY+AG DK
Sbjct: 488 PRQRGQLMLNLADLMERNKEELATIESVDSGAVYTLALKTHVGMSIEAWRYFAGWCDKIQ 547
Query: 139 GGEYIPLNQDK----YAYTMKVPYGVVAQIVPWNYPLAMASWKIQSCLAAGNTIVIKPAE 194
G IP+N + +T K P GV I PWNYPL M SWK+ +C+AAGNT +IKPA+
Sbjct: 548 GNT-IPVNPARPNNVLTFTRKEPIGVCGLITPWNYPLMMLSWKMAACIAAGNTCLIKPAQ 606
Query: 195 NTSLSLLYFAQLVKEAGFPPGVLNILPGYGSVTGTAMASHTDIDKIAFTGSTAVGQKVMS 254
L+ L FA+L AGFPPGV+N+LPG GS G A+A H + K+ FTGST +G+ +M
Sbjct: 607 TCPLTALKFAELTVRAGFPPGVINVLPGKGSDAGQAVADHELVRKLGFTGSTPIGKHIMK 666
Query: 255 LAAQSNLKAVTLECGGKSPCLIFADANLDEAIPWVAGGIFYNSGQNCTANSRIYVHEDIY 314
A SNLK +LE GGKSP +IFAD ++D+A+ +F+N G+NC A R++V + I+
Sbjct: 667 SCADSNLKKCSLELGGKSPLIIFADCDMDKAVKHGMSSVFFNKGENCIAAGRLFVEDRIH 726
Query: 315 EEFLTKFEEYAKSNWKFGAKFDPFDKDCTLGPVISKVQYDRIQSYVEHG 363
+EF+ + + ++ G DP D+ GP K +D++ + G
Sbjct: 727 DEFIRRVLKDLRT-MTIG---DPLDRSTAHGPQNHKAHFDKLLEFCRRG 771
>CE07233 [C] KOG2450 Aldehyde dehydrogenase
Length = 687
Score = 274 bits (701), Expect = 2e-73
Identities = 157/479 (32%), Positives = 263/479 (54%), Gaps = 12/479 (2%)
Query: 23 FINNEFVKSSDGKKIESINPSTEESIVSFFAASEKDVNSAVTAARDAFENNWSKTSGEQR 82
F+ V+ +K E I P + + + ++ A+ V+ V A+ A + W+K+S +R
Sbjct: 209 FVAGNHVEFPSDRKFEVIEPRSGKPMATWHYATRDQVDLTVKEAKKA-QKQWAKSSWMER 267
Query: 83 GILLSKLFDLIERDKLLLAAIETLDSGKPYHSNSLADLEQILQLTRYYAGGADKFTGGEY 142
+L K DL++ +A E + +GKP + + AD+ + +Y+G A G ++
Sbjct: 268 SEILKKTGDLLKTHCNDIAYWECISNGKPI-AEAKADVLSCVDTFYFYSGIASDLLG-QH 325
Query: 143 IPLNQDKYAYTMKVPYGVVAQIVPWNYPLAMASWKIQSCLAAGNTIVIKPAENTSLSLLY 202
+PL+ +YAYT ++P GVVA I WNYP+ SWK LA GN ++ KP+ + ++ L
Sbjct: 326 VPLDASRYAYTRRLPVGVVAAIGAWNYPIQTCSWKTAPALACGNAVIYKPSPLSPVTALI 385
Query: 203 FAQLVKEAGFPPGVLNILPGYGSVTGTAMASHTDIDKIAFTGSTAVGQKVMSLAAQSNLK 262
A+++K AG P GV N++ G + T + H + K++FTGS G+K+M A N+K
Sbjct: 386 LAEILKSAGLPDGVFNVIQG-DAETAQDLIHHDGVSKVSFTGSIPTGKKIMKACADRNIK 444
Query: 263 AVTLECGGKSPCLIFADANLDEAIPWVAGGIFYNSGQNCTANSRIYVHEDIYEEFLTKFE 322
VTLE GGKS ++F DA++D A+ FY+ GQ C+ S++ VH+ + +EF K
Sbjct: 445 PVTLELGGKSALIVFDDADIDSAVSCAMMANFYSQGQVCSNASKVLVHKSVLKEFTKKLV 504
Query: 323 EYAKSNWKFGAKFDPFDKDCTLGPVISKVQYDRIQSYVEH--GKASEKL--GFKEFAEYP 378
++ + K G DP +D +G IS ++++ Y+ + + KL G +
Sbjct: 505 DHTQ-KMKIG---DPLKEDTQVGSHISAEHRNKVEGYISTAIAEGATKLCGGDRVAVHGL 560
Query: 379 SKGYFIPPTIFSDVPNSSKLSQEEIFGPVGVVASFSTYEEAIKLANDSSYGLASCVFSEN 438
G+++ P I + + + +EEIFG V ++ F T +EAIK+AND+ GLA+ + +++
Sbjct: 561 ENGFYLSPCILTGITPKMTVYREEIFGSVLLIIPFDTEDEAIKIANDTDMGLAAGLVTKD 620
Query: 439 ARTTAQFARDIRAGTVWINSSNDEEISVPFGGFKMSGIGRELGRNGVDSYLQTKAVHVN 497
+ + + + AG V++N+ ND VPFGG SG GRE G ++ Y K+V VN
Sbjct: 621 LSRSYRVSEQLNAGNVYVNTYNDVSPLVPFGGVGESGFGRENGTAVLEHYTHLKSVFVN 679
>SPAC139.05 [C] KOG2451 Aldehyde dehydrogenase
Length = 493
Score = 261 bits (668), Expect = 1e-69
Identities = 167/480 (34%), Positives = 259/480 (53%), Gaps = 16/480 (3%)
Query: 23 FINNEFVKSSDGKKIESINPSTEESIVSFFAASEKDVNSAVTAARDAFENNWSKTSGEQR 82
F+ +++ S + K E NP+T E I S ++ A++AA +AF+ + + QR
Sbjct: 21 FVQGKWISSPNNKTFEVDNPATGEIIGKVADVSVEETKKAISAANEAFKT-YKNFTHVQR 79
Query: 83 GILLSKLFDLIERDKLLLAAIETLDSGKPYHSNSLADLEQILQLTRYYAGGADKFTGGEY 142
LL + +LI +K L + TL++GKP S + ++ ++YA A + T G+
Sbjct: 80 SQLLERWAELIMENKDDLVKMLTLENGKPL-SQAEMEVTTCSGYLKWYAAEAVR-TFGDV 137
Query: 143 IP--LNQDKYAYTMKVPYGVVAQIVPWNYPLAMASWKIQSCLAAGNTIVIKPAENTSLSL 200
P L + ++K P GV A I PWN+P AM + K + LAAG T + PA T
Sbjct: 138 APSSLQSQNFLISIKQPVGVSALITPWNFPAAMIARKGGAALAAGCTAIFLPAFRTPYVC 197
Query: 201 LYFAQLVKEAGFPPGVLNILPGY-GSVTGTAMASHTDIDKIAFTGSTAVGQKVMSLAAQS 259
L +L +EAGFP GVLN++ S G + ++ + K++FTGST VG+ +M +A S
Sbjct: 198 LGLVRLAQEAGFPDGVLNVITSSDASAHGKELTTNPIVRKVSFTGSTNVGKILMGQSA-S 256
Query: 260 NLKAVTLECGGKSPCLIFADANLDEAIPWVAGGIFYNSGQNCTANSRIYVHEDIYEEFLT 319
+K V++E GG +P ++F D +D+A+ F + GQ C +R+YVH+++Y+EF++
Sbjct: 257 TIKKVSMELGGNAPFIVFPDFPIDQAVESFCTIKFNSCGQVCVCPNRVYVHKNVYDEFVS 316
Query: 320 KFEEYAKSNWKFGAKFDPFDKDCTLGPVISKVQYDRIQSYVEHGK---ASEKLGFKEFAE 376
K E K+ K G D FD +GP+IS+ ++ ++E A +G KE +
Sbjct: 317 KLTEKVKTI-KVG---DGFDSSSAVGPLISQDGCKKVSKHIEDAVSKGAKITVGGKEISS 372
Query: 377 YPSKGYFIPPTIFSDVPNSSKLSQEEIFGPVGVVASFSTYEEAIKLANDSSYGLASCVFS 436
SKGYF PT+ S V ++ EE FGP+ V F EE I+ ANDS GLA VF+
Sbjct: 373 --SKGYFFEPTVLSGVTQDMLVASEETFGPLASVFKFDDTEEVIEWANDSDVGLAGYVFT 430
Query: 437 ENARTTAQFARDIRAGTVWINSSNDEEISVPFGGFKMSGIGRELGRNGVDSYLQTKAVHV 496
N T A+++ G V N +E + FGG K SG G+E GR GV ++ K +++
Sbjct: 431 NNLSTMIHVAKELEVGLVGANIEMVDEPFISFGGIKQSGFGKEAGRLGVQEFMVVKEINL 490
>CE24573 [C] KOG2450 Aldehyde dehydrogenase
Length = 574
Score = 260 bits (664), Expect = 4e-69
Identities = 165/483 (34%), Positives = 248/483 (51%), Gaps = 13/483 (2%)
Query: 23 FINNEFVKSSDGKKIESINPSTEESIVSFFAASEKDVNSAVTAARDAFENNWSKTSGEQR 82
F+N + + + I P + + A+ V+ V AA DA ++ W +T+ R
Sbjct: 90 FLNGKRTTIESTETFDVIEPRIGQVVAKCPKATADIVDQYVKAAADA-QSAWGETTALDR 148
Query: 83 GILLSKLFDLIERDKLLLAAIETLDSGKPYHSNSLADLEQILQLTRYYAGGADKFTGGEY 142
G +L K+ DLI +A E +GKP + + D+ ++ G A G+
Sbjct: 149 GKVLHKVADLIREHAEEIAIWEVKTNGKPIYE-ARCDIASSADTFDFFGGIATAVLQGDS 207
Query: 143 IPLN---QDKYAYTMKVPYGVVAQIVPWNYPLAMASWKIQSCLAAGNTIVIKPAENTSLS 199
+ L + AYT + PYGVV I WNYP WK+ LAAGN +V KP+ S
Sbjct: 208 LELPGGPSQRIAYTRREPYGVVGCIGAWNYPFQTCVWKVAPALAAGNAVVYKPSPFAPAS 267
Query: 200 LLYFAQLVKEAGFPPGVLNILPGYGSVTGTAMASHTDIDKIAFTGSTAVGQKVMSLAAQS 259
+ +++ AG P GV N++ G G A+ H + K++FTGS A G+ V AA
Sbjct: 268 PVLLGEILTAAGVPKGVYNVIQGEQEA-GVALCEHNLVAKVSFTGSVASGEAVQRQAATK 326
Query: 260 NLKAVTLECGGKSPCLIFADANLDEAIPWVAGGIFYNSGQNCTANSRIYVHEDIYEEFLT 319
N+K VTLE GGKS +IF D+++ A+ F N GQ CT +R++V + I F
Sbjct: 327 NVKPVTLELGGKSEIIIFDDSDVKSAVASAMLANFLNQGQVCTNATRVFVQKGILASFTE 386
Query: 320 KFEEYAKSNWKFGAKFDPFDKDCTLGPVISKVQYDRIQSYVEHGKASEKL----GFKEFA 375
+ A K G DP +D +G I++ RI YVE K + G +
Sbjct: 387 AIVQEANDKLKVG---DPLLEDTRVGANINEGHLQRILGYVESAKQEGGVVLRGGVRVHP 443
Query: 376 EYPSKGYFIPPTIFSDVPNSSKLSQEEIFGPVGVVASFSTYEEAIKLANDSSYGLASCVF 435
G + P I + + + ++ +EEIFG V ++ F T EE I AN+++YGLA+ VF
Sbjct: 444 TGVEGGAYFEPAIITGLSDEARAVREEIFGAVMLILPFETEEEVIARANNTTYGLAAGVF 503
Query: 436 SENARTTAQFARDIRAGTVWINSSNDEEISVPFGGFKMSGIGRELGRNGVDSYLQTKAVH 495
S N + A ++AGTV+IN+ ND E++VPFGGFK SG GRE + + ++ QTKA++
Sbjct: 504 SGNLARGHRVAARLQAGTVFINTYNDTEVNVPFGGFKNSGHGRENCIDTLRAHTQTKAIY 563
Query: 496 VNI 498
VN+
Sbjct: 564 VNV 566
>7301355 [C] KOG2451 Aldehyde dehydrogenase
Length = 509
Score = 256 bits (654), Expect = 6e-68
Identities = 156/475 (32%), Positives = 255/475 (52%), Gaps = 10/475 (2%)
Query: 24 INNEFVKSSDGKK-IESINPSTEESIVSFFAASEKDVNSAVTAARDAFENN-WSKTSGEQ 81
++ +V SS+ K E NP+ I + D A+ AA+ A+E+ W + +
Sbjct: 33 VDGAWVDSSNAKATFEVRNPANGAVIGKVPNMTVADAQKAIDAAKQAYESKEWRSLTAKD 92
Query: 82 RGILLSKLFDLIERDKLLLAAIETLDSGKPYHSNSLADLEQILQLTRYYAGGADKFTGGE 141
R LL K LIE+ +A I T +SGKP + S ++ ++A A + G
Sbjct: 93 RSNLLKKWHKLIEQHSQEIAEIMTAESGKPINE-SKGEVAYGNAFVEWFAEEARRIYGEI 151
Query: 142 YIPLNQDKYAYTMKVPYGVVAQIVPWNYPLAMASWKIQSCLAAGNTIVIKPAENTSLSLL 201
+ ++ MK P GV A I PWN+P+AM + K + LAAG T+V+KP+E+T L+ L
Sbjct: 152 VPSASPNREIIVMKQPIGVAALITPWNFPMAMITRKAGAALAAGCTVVVKPSEDTPLTAL 211
Query: 202 YFAQLVKEAGFPPGVLNILP-GYGSVTGTAMASHTDIDKIAFTGSTAVGQKVMSLAAQSN 260
A+L +AG P GV+N++ + G D+ I+FTGST VG K++ +
Sbjct: 212 AVAKLAVDAGIPKGVINVVTTNKAAPIGDLFCKSPDVRGISFTGSTEVG-KLLFRNSADG 270
Query: 261 LKAVTLECGGKSPCLIFADANLDEAIPWVAGGIFYNSGQNCTANSRIYVHEDIYEEFLTK 320
+K + LE GG +P ++F A++++A+ F N GQ C + +R +V + +Y++F+ +
Sbjct: 271 IKRICLELGGNAPFIVFDSADIEKAVDGAMASKFRNCGQTCVSANRFFVQDSVYDKFVGQ 330
Query: 321 FEEYAKSNWKFGAKFDPFDKDCTLGPVISKVQYDRIQSYVEHGKASEKLGFKEFAEYPSK 380
++ ++ K G D D +GP+I+++Q++++ +VE ++ + P K
Sbjct: 331 LKKRVEA-LKIG---DGQGCDVQIGPLINEMQFNKVSGFVEDARSKKANIILGGQPLPDK 386
Query: 381 G-YFIPPTIFSDVPNSSKLSQEEIFGPVGVVASFSTYEEAIKLANDSSYGLASCVFSENA 439
G F PTI +DVP S++L EE+FGPV + F EEA+K AND+ GLA +SEN
Sbjct: 387 GSLFYAPTIVTDVPPSAQLYSEEVFGPVVSIIRFRDEEEAVKKANDTRRGLAGYFYSENL 446
Query: 440 RTTAQFARDIRAGTVWINSSNDEEISVPFGGFKMSGIGRELGRNGVDSYLQTKAV 494
+ + A+ + G V +N PFGG K SG+GRE ++G+D Y+ K +
Sbjct: 447 QQVFRVAKRLEVGMVGVNEGIISAAEAPFGGVKESGVGREGSKHGIDDYVDIKYI 501
>SPAC1002.12c [C] KOG2451 Aldehyde dehydrogenase
Length = 498
Score = 246 bits (629), Expect = 4e-65
Identities = 159/506 (31%), Positives = 261/506 (51%), Gaps = 31/506 (6%)
Query: 6 TVNIPQLNI--TYEQPLGLFINNEFVKSSDGKKIESINPSTEESIVSFFAASEKDVNSAV 63
+ NI L++ E P +I ++V ++ GK + NP E++ S ++ A+
Sbjct: 8 STNIKDLSLFDLEEFPARSYIGGKWVTAASGKTFDVENPGLNETLAPVTDMSVEETRKAI 67
Query: 64 TAARDAFENNWSKTSGEQRGILLSKLFDLIERDKLLLAAIETLDSGKPYHSNSLADLEQI 123
A +AF + + + ++R +L + +DLI + LA + TL++GK ++ ++
Sbjct: 68 KVAHEAFLS-YRNSDIKERYAILRRWYDLIMENADDLATMMTLENGKAL-GDAKGEVVYA 125
Query: 124 LQLTRYYAGGADKFTGGEYIPLNQDKYAYTMKVPYGVVAQIVPWNYPLAMASWKIQSCLA 183
+ ++AG A + +G + N T+K P GVV I PWN+P AM + K+ + LA
Sbjct: 126 AKFIDWFAGEALRISGDSSMSSNPQNRIITIKQPVGVVGIITPWNFPAAMITRKVGAALA 185
Query: 184 AGNTIVIKPAENTSLSLLYFAQLVKEAGFPPGVLNILPGYG-SVTGTAMASHTDIDKIAF 242
AG T+VI+PA T + L A+L + AG P GVLN++ S G + ++ I K++F
Sbjct: 186 AGCTVVIRPAAETPFTALALAKLAERAGVPAGVLNMVTANSPSEHGIELTTNPLIRKVSF 245
Query: 243 TGSTAVGQKVMSLAAQSNLKAVTLECGGKSPCLIFADANLDEAIPWVAGGIFYNSGQNCT 302
TGST VG K+++ + S LK ++LE GG +P ++F DA+L++A + F SGQ C
Sbjct: 246 TGSTNVG-KILAKQSSSTLKKLSLELGGNAPFIVFEDADLEKAADALMACKFRGSGQTCV 304
Query: 303 ANSRIYVHEDIYEEFLTKFEEYAKSNWKFGAKFDPFDKDCTLGPVISKVQYDRIQSYVEH 362
+RIYVH +Y+ F+ E S +K G D T GP+IS+ +++ +VE
Sbjct: 305 CANRIYVHSSVYDAFVDLVTERV-SKFKLGYGLDA---GVTHGPLISEKAISKVKQHVED 360
Query: 363 -----------GKASEKLGFKEFAEYPSKGYFIPPTIFSDVPNSSKLSQEEIFGPVGVVA 411
GK + LG + PT+ + +S+EE FGPVG +
Sbjct: 361 AVQKGGVVVTGGKVASNLG----------PMYFEPTVIINAKQGMLISEEETFGPVGALF 410
Query: 412 SFSTYEEAIKLANDSSYGLASCVFSENARTTAQFARDIRAGTVWINSSNDEEISVPFGGF 471
F T +E + ANDS GLA +FS++ + ++ G V N+ ++ PFGG
Sbjct: 411 KFDTEDEVVAWANDSPVGLAGYLFSKDISRVFRVGEALQVGMVGCNTGLVSDVLSPFGGV 470
Query: 472 KMSGIGRELGRNGVDSYLQTKAVHVN 497
K SG GRE + G+ YL K++ ++
Sbjct: 471 KESGFGREGSKYGISEYLDIKSLTIS 496
>Hs4507229 [C] KOG2451 Aldehyde dehydrogenase
Length = 535
Score = 243 bits (619), Expect = 6e-64
Identities = 146/441 (33%), Positives = 233/441 (52%), Gaps = 9/441 (2%)
Query: 57 KDVNSAVTAARDAFENNWSKTSGEQRGILLSKLFDLIERDKLLLAAIETLDSGKPYHSNS 116
++ +AV AA +AF W + S ++R LL K ++L+ ++K LA I T +SGKP +
Sbjct: 96 REARAAVRAAYEAF-CRWREVSAKERSSLLRKWYNLMIQNKDDLARIITAESGKPL-KEA 153
Query: 117 LADLEQILQLTRYYAGGADKFTGGEYIPLNQDKYAYTMKVPYGVVAQIVPWNYPLAMASW 176
++ +++ A + G +D+ A +K P GV A I PWN+P AM +
Sbjct: 154 HGEILYSAFFLEWFSEEARRVYGDIIHTPAKDRRALVLKQPIGVAAVITPWNFPSAMITR 213
Query: 177 KIQSCLAAGNTIVIKPAENTSLSLLYFAQLVKEAGFPPGVLNILP---GYGSVTGTAMAS 233
K+ + LAAG T+V+KPAE+T S L A+L +AG P GV N++P G A+ +
Sbjct: 214 KVGAALAAGCTVVVKPAEDTPFSALALAELASQAGIPSGVYNVIPCSRKNAKEVGEAICT 273
Query: 234 HTDIDKIAFTGSTAVGQKVMSLAAQSNLKAVTLECGGKSPCLIFADANLDEAIPWVAGGI 293
+ KI+FTGST G+ ++ AA S +K V++E GG +P ++F AN+D+A+
Sbjct: 274 DPLVSKISFTGSTTTGKILLHHAANS-VKRVSMELGGLAPFIVFDSANVDQAVAGAMASK 332
Query: 294 FYNSGQNCTANSRIYVHEDIYEEFLTKFEEYAKSNWKFGAKFDPFDKDCTLGPVISKVQY 353
F N+GQ C +++ V I++ F+ F E K N + G + F++ T GP+I++
Sbjct: 333 FRNTGQTCVCSNQFLVQRGIHDAFVKAFAEAMKKNLRVG---NGFEEGTTQGPLINEKAV 389
Query: 354 DRIQSYVEHGKASEKLGFKEFAEYPSKGYFIPPTIFSDVPNSSKLSQEEIFGPVGVVASF 413
++++ V + + F PT+ +V + EE FGP+ V F
Sbjct: 390 EKVEKQVNDAVSKGATVVTGGKRHQLGKNFFEPTLLCNVTQDMLCTHEETFGPLAPVIKF 449
Query: 414 STYEEAIKLANDSSYGLASCVFSENARTTAQFARDIRAGTVWINSSNDEEISVPFGGFKM 473
T EEAI +AN + GLA +S++ + A + G V +N + PFGG K
Sbjct: 450 DTEEEAIAIANAADVGLAGYFYSQDPAQIWRVAEQLEVGMVGVNEGLISSVECPFGGVKQ 509
Query: 474 SGIGRELGRNGVDSYLQTKAV 494
SG+GRE + G+D YL+ K V
Sbjct: 510 SGLGREGSKYGIDEYLELKYV 530
>CE10542 [C] KOG2451 Aldehyde dehydrogenase
Length = 569
Score = 240 bits (613), Expect = 3e-63
Identities = 152/472 (32%), Positives = 245/472 (51%), Gaps = 15/472 (3%)
Query: 23 FINNEFVKSSDGKKIESINPSTEESIVSFFAASEKDVNSAVTAARDAFENNWSKT-SGEQ 81
+I ++ S G + +NP E + + KD AV +A + F+ W+ T S +Q
Sbjct: 21 YIGGKWTASETGNSFDVLNPFNNEVVDRATNCTVKDAEKAVHSALEGFDK-WAHTYSAKQ 79
Query: 82 RGILLSKLFDLIERDKLLLAAIETLDSGKPYHSNSLADLEQILQLTRYYAGGADKFTGGE 141
RG +L K F+++ + + LA + T + GKP + + +++ +YAG A + G
Sbjct: 80 RGAILHKWFEILVQRETELATLLTKEQGKPL-AEARGEIQYSAAYFDWYAGEARRVYGQV 138
Query: 142 YIPLNQDKYAYTMKVPYGVVAQIVPWNYPLAMASWKIQSCLAAGNTIVIKPAENTSLSLL 201
++ + P GVVA I PWN+P AM + K + L+ G + V+KP+ +T LS L
Sbjct: 139 VPSAVVNRLHLHTREPIGVVALIAPWNFPTAMIARKAAAALSVGCSAVVKPSGDTPLSAL 198
Query: 202 YFAQLVKEAGFPPGVLNILPGYGSVTGTA---MASHTDIDKIAFTGSTAVGQKVMSLAAQ 258
AQ +EAG P GV N++ S T + TD+ I+FTGST VG+ +++ +A
Sbjct: 199 ALAQTAEEAGIPAGVFNVITADHSNTAEISKYLCESTDVSAISFTGSTPVGKLLLAQSA- 257
Query: 259 SNLKAVTLECGGKSPCLIFADANLDEAIPWVAGGIFYNSGQNCTANSRIYVHEDIYEEFL 318
S +K V LE GG +P ++F DA+LD A+ F SGQ C + +RIYVHE I+++++
Sbjct: 258 STVKRVCLELGGNAPLIVFDDADLDVAVNGTMATKFRCSGQTCVSANRIYVHEKIHDQYI 317
Query: 319 TKFEEYAKSNWKFGAKFDPFDKDCTLGPVISKVQYDRIQSYVEH--GKASEKLGFKEFAE 376
+K K G +P T GP++++ D+ + + GK SE + + E
Sbjct: 318 SKLAAAMKEKLVLGDGLNP---KTTQGPLVNQKAVDKCELLLSDALGKGSELICGGKRGE 374
Query: 377 YPSKGYFIPPTIFSDVPNSSKLSQEEIFGPVGVVASFSTYEEAIKLANDSSYGLASCVFS 436
+ G PT+ ++V +++ ++ EIFGP+ V F +E ++ AN+ GLA VF
Sbjct: 375 H---GTSYEPTLITNVQSNTNIAHTEIFGPIASVQKFRDEQEVLEAANNCRVGLAGYVFG 431
Query: 437 ENARTTAQFARDIRAGTVWINSSNDEEISVPFGGFKMSGIGRELGRNGVDSY 488
+ + AR + G V +N FGG K SGIGRE G G+D +
Sbjct: 432 RDQSRLQRVARKLEVGMVGVNEGLISCAEAAFGGVKESGIGREGGAQGIDEF 483
>YBR006w [C] KOG2451 Aldehyde dehydrogenase
Length = 497
Score = 235 bits (599), Expect = 1e-61
Identities = 151/477 (31%), Positives = 240/477 (49%), Gaps = 11/477 (2%)
Query: 23 FINNEFVKSSDGKKIESINPSTEESIVSFFAASEKDVNSAVTAARDAFENNWSKTSGEQR 82
+I+ ++VK +D + E ++P++ E I V A+ A + F+ + T+ +R
Sbjct: 22 YIDGKWVKGTD-EVFEVVDPASGEIIARVPEQPVSVVEEAIDVAYETFKT-YKNTTPRER 79
Query: 83 GILLSKLFDLIERDKLLLAAIETLDSGKPYHSNSLADLEQILQLTRYYAGGADKFTGGEY 142
L +++L+ + LA I TL++GK + +++ +YA A + G
Sbjct: 80 AKWLRNMYNLMLENLDDLATIITLENGKAL-GEAKGEIKYAASYFEWYAEEAPRLYGATI 138
Query: 143 IPLNQDKYAYTMKVPYGVVAQIVPWNYPLAMASWKIQSCLAAGNTIVIKPAENTSLSLLY 202
PLN +T++ P GV I PWN+P AM + K + LA G T+VIKP T LS L
Sbjct: 139 QPLNPHNRVFTIRQPVGVCGIICPWNFPSAMITRKAAAALAVGCTVVIKPDSQTPLSALA 198
Query: 203 FAQLVKEAGFPPGVLNILPGYGSVT--GTAMASHTDIDKIAFTGSTAVGQKVMSLAAQSN 260
A L ++AGFP G N++ + + G + + K+ FTGST VG K++ + S
Sbjct: 199 MAYLAEKAGFPKGSFNVILSHANTPKLGKTLCESPKVKKVTFTGSTNVG-KILMKQSSST 257
Query: 261 LKAVTLECGGKSPCLIFADANLDEAIPWVAGGIFYNSGQNCTANSRIYVHEDIYEEFLTK 320
LK ++ E GG +P ++F DA+LD+A+ F GQ C +R+YVH I ++F
Sbjct: 258 LKKLSFELGGNAPFIVFEDADLDQALEQAMACKFRGLGQTCVCANRLYVHSSIIDKFAKL 317
Query: 321 FEEYAKSNWKFGAKFDPFDKDCTLGPVISKVQYDRIQSYVEHGKASEKLGFKEFAEYPSK 380
E K + G DP T G VI+ ++++ + + E
Sbjct: 318 LAERVKK-FVIGHGLDP---KTTHGCVINSSAIEKVERHKQDAIDKGAKVVLEGGRLTEL 373
Query: 381 G-YFIPPTIFSDVPNSSKLSQEEIFGPVGVVASFSTYEEAIKLANDSSYGLASCVFSENA 439
G F P I S VP+++ +S+EE FGP+ + SF T EE + AND+ +GLA+ VFS+N
Sbjct: 374 GPNFYAPVILSHVPSTAIVSKEETFGPLCPIFSFDTMEEVVGYANDTEFGLAAYVFSKNV 433
Query: 440 RTTAQFARDIRAGTVWINSSNDEEISVPFGGFKMSGIGRELGRNGVDSYLQTKAVHV 496
T + + G V N+ + S+PFGG K SG GRE G++ Y K + +
Sbjct: 434 NTLYTVSEALETGMVSCNTGVFSDCSIPFGGVKESGFGREGSLYGIEDYTVLKTITI 490
>At3g66658 [C] KOG2454 Betaine aldehyde dehydrogenase
Length = 578
Score = 207 bits (528), Expect = 2e-53
Identities = 152/475 (32%), Positives = 236/475 (49%), Gaps = 24/475 (5%)
Query: 35 KKIESINPSTEESIVSFFAASEKDVNSAVTAARDAFENNWSKTSGEQRGILLSKLFDLIE 94
KK++ P+T + + F A S +V VT +R A + W+++S + R L L I
Sbjct: 64 KKVQCYEPATMKYLGYFPALSPTEVEERVTLSRKA-QKTWAQSSFKLRRQFLRILLKYII 122
Query: 95 RDKLLLAAIETLDSGKPYHSNSLADLEQILQLTRYYAGGADKFTGGEYIPLNQDKYAYTM 154
+ L+ + + D+GK SL ++ + + +++ E +
Sbjct: 123 EHQELICEVSSRDTGKTMVDASLGEIMTTCEKITWLLSEGERWLKPESRSSGRAMLHKVS 182
Query: 155 KV---PYGVVAQIVPWNYPLAMASWKIQSCLAAGNTIVIKPAENTSLSLLYFAQLVKEA- 210
+V P GV+ IVPWNYP + + + +GN IVIK +E+ S S ++ ++++ A
Sbjct: 183 RVEFHPLGVIGAIVPWNYPFHNIFNPMLAAVFSGNGIVIKVSEHASWSGCFYFRIIQAAL 242
Query: 211 ---GFPPGVLNILPGYGSVTGTAMASHTDIDKIAFTGSTAVGQKVMSLAAQSNLKAVTLE 267
G P +++++ G+ TG A+ S +DK+ F GSTAVG+ +M AA++ L VTLE
Sbjct: 243 AAVGAPENLVDVITGFAE-TGEALVS--SVDKMIFVGSTAVGKMIMRNAAET-LTPVTLE 298
Query: 268 CGGKSPCLIFADANLDEAIPWVAGGIFYNSGQNCTANSRIYVHEDIYEEFLTKFEEYAKS 327
GGK +I DA++ G +SGQNC R YVH+DIY F+ + + KS
Sbjct: 299 LGGKDAFIICEDADVSHVAQVAVRGTLQSSGQNCAGAERFYVHKDIYTAFIGQVTKIVKS 358
Query: 328 NWKFGAKFDPFDKDCTLGPVISKVQYDRIQSYVEHG--KASE---KLGFKEFAEYPSKGY 382
+ P +G + + + +QS V K +E + F E Y
Sbjct: 359 V----SAGPPLTGRYDMGAICLQEHSEHLQSLVNDALDKGAEIAVRGSFGHLGEDAVDQY 414
Query: 383 FIPPTIFSDVPNSSKLSQEEIFGPVGVVASFSTYEEAIKLANDSSYGLASCVFSENARTT 442
F PPT+ +V ++ K+ +EE FGP+ + FST EE IKLANDS Y L VFS +
Sbjct: 415 F-PPTVLINVNHNMKIMKEEAFGPIMPIMQFSTDEEVIKLANDSRYALGCAVFSGSKHRA 473
Query: 443 AQFARDIRAGTVWIN--SSNDEEISVPFGGFKMSGIGRELGRNGVDSYLQTKAVH 495
Q A I+ G IN +SN S+PFGG K SG GR G G+ + K+V+
Sbjct: 474 KQIASQIQCGVAAINDFASNYMCQSLPFGGVKDSGFGRFAGIEGLRACCLVKSVY 528
>At2g24270 [C] KOG2450 Aldehyde dehydrogenase
Length = 496
Score = 201 bits (511), Expect = 2e-51
Identities = 144/485 (29%), Positives = 243/485 (49%), Gaps = 24/485 (4%)
Query: 23 FINNEFVKSSDGKKIESINPSTEESIVSFFAASEKDVNSAVTAARDAFENNWSKTSGEQR 82
+ + E+ SS GK + +NP+T ++ A ++++VN+ + A+ A + +W+KT +R
Sbjct: 19 YADGEWKTSSSGKSVAIMNPATRKTQYKVQACTQEEVNAVMELAKSA-QKSWAKTPLWKR 77
Query: 83 GILLSKLFDLIERDKLLLAAIETLDSGKPYHSNSLADLEQILQLTRYYAG------GADK 136
LL K +++ +K +A + KP +S+ ++ + L Y A G K
Sbjct: 78 AELLHKAAAILKDNKAPMAESLVKEIAKPA-KDSVTEVVRSGDLISYCAEEGVRILGEGK 136
Query: 137 FTGGEYIPLN-QDKYAYTMKVPYGVVAQIVPWNYPLAMASWKIQSCLAAGNTIVIKPAEN 195
F + P N + KY T K+P GVV I P+NYP+ +A KI L AGN++V+KP
Sbjct: 137 FLLSDSFPGNDRTKYCLTSKIPLGVVLAIPPFNYPVNLAVSKIAPALIAGNSLVLKPPTQ 196
Query: 196 TSLSLLYFAQLVKEAGFPPGVLNILPGYGSVTGTAMASHTDIDKIAFTGSTAVGQKVMSL 255
++S L+ AGFP G+++ + G GS G + H ++ I+FTG G +S+
Sbjct: 197 GAVSCLHMVHCFHLAGFPKGLISCITGKGSEIGDFLTMHPAVNCISFTG----GDTGISI 252
Query: 256 AAQSNLKAVTLECGGKSPCLIFADANLDEAIPWVAGGIFYNSGQNCTANSRIYVHEDIYE 315
+ ++ + + +E GGK C++ DA+LD + G F SGQ CTA + V E + +
Sbjct: 253 SKKAGMIPLQMELGGKDACIVLDDADLDLVASNIIKGGFSYSGQRCTAVKVVLVMESVAD 312
Query: 316 EFLTKFE-EYAKSNWKFGAKFDPFDKDCTLGPVISKVQYDRIQSYVEHGKASEKLGFKEF 374
E + K + + AK P +++ + V+S+ + I+ V K + G
Sbjct: 313 ELVEKVKAKVAK------LTVGPPEENSDITAVVSESSANFIEGLVMDAK---EKGATFC 363
Query: 375 AEYPSKGYFIPPTIFSDVPNSSKLSQEEIFGPVGVVASFSTYEEAIKLANDSSYGLASCV 434
EY +G I P + +V +++ EE FGPV V ++ EE I N S++GL CV
Sbjct: 364 QEYKREGNLIWPLLLDNVRPDMRIAWEEPFGPVVPVLRINSVEEGINHCNASNFGLQGCV 423
Query: 435 FSENARTTAQFARDIRAGTVWINSSNDE-EISVPFGGFKMSGIGRELGRNGVDSYLQTKA 493
F+++ + + GTV INS+ PF G K SGIG + N ++ + K
Sbjct: 424 FTKDINKAILISDAMETGTVQINSAPARGPDHFPFQGLKDSGIGSQGVTNSINLMTKVKT 483
Query: 494 VHVNI 498
+N+
Sbjct: 484 TVINL 488
>CE02183 [EG] KOG2449 Methylmalonate semialdehyde dehydrogenase
Length = 523
Score = 197 bits (502), Expect = 2e-50
Identities = 155/493 (31%), Positives = 237/493 (47%), Gaps = 42/493 (8%)
Query: 22 LFINNEFVKSSDGKKIESINPSTEESIVSFFAASEKDVNSAVTAARDAFENNWSKTSGEQ 81
L+I+ + V+S +E NP+T E I A++ ++ +AV +A++AF N W TS
Sbjct: 32 LWIDGQAVESKTTDFVELTNPATNEVIAMVPNATQAEMQAAVDSAKNAF-NTWKNTSPLT 90
Query: 82 RGILLSKLFDLIERDKLLLAAIETLDSGKPYHSNSLADLEQILQLTRYYAGGADKFTGGE 141
R + KL LI+RD LA T++ GK ++ D+ + LQ+ + A GE
Sbjct: 91 RQQCMFKLQALIKRDMKKLAESITIEQGKTL-PDAEGDVSRGLQVVEH-ACSVPSLMMGE 148
Query: 142 YIP-LNQDKYAYTMKVPYGVVAQIVPWNYPLAMASWKIQSCLAAGNTIVIKPAENTSLSL 200
+P +++D ++ ++P GV A I P+N+P + W LA GNT+VIKP+E +
Sbjct: 149 TLPNVSRDMDTHSYRIPLGVTAGICPFNFPAMIPLWMFPVALATGNTMVIKPSEQDPGAA 208
Query: 201 LYFAQLVKEAGFPPGVLNILPGYGSVTGTAMASHTDIDKIAFTGSTAVGQKVMSLAAQSN 260
+L KEAG P G +NI+ G S + + DI I+F G A G+ + A+ N
Sbjct: 209 QLLVELAKEAGVPDGCVNIIHGQHSAV-NFICDNPDIKAISFVGGDAAGKHIYERGAK-N 266
Query: 261 LKAVTLECGGKSPCLIFADANLDEAIPWVAGGIFYNSGQNCTA-NSRIYVHEDIYEEFLT 319
K V G K+ +I ADAN ++ + + F +GQ C A + + V E +L
Sbjct: 267 GKRVQSNMGAKNHGVIMADANKEQTLNQLTAAAFGAAGQRCMALTTAVLVGE--ARAWLP 324
Query: 320 KFEEYAKSNWKFGAKFDPFDKDCTLGPVISKVQYDRIQSYVEHGKASEKLGFKEFAEYP- 378
+ E AK N K A + P D +GP+ISK R+ +E K KE A+ P
Sbjct: 325 ELVEKAK-NLKVNAGWKP---DTDIGPLISKQSKARVLRLIESAK-------KEGAQVPL 373
Query: 379 ----------SKGYFIPPTIFSDVPNSSKLSQEEIFGPVGVVASFSTYEEAIKLANDSSY 428
G F+ PTI + V + +EEIFGPV VV EAI++ N++ Y
Sbjct: 374 DGSNITVPGFENGNFVGPTILAGVKPNMTCYREEIFGPVLVVMEAENLNEAIEIINNNPY 433
Query: 429 GLASCVFSENARTTAQFARDIRAGTVWINSSNDEEISVPFGGFKMSGIGREL-------G 481
G + +F+ N T +F ++ G + IN I VP F +G G
Sbjct: 434 GNGTAIFTSNGATARKFTNEVDVGQIGIN----VPIPVPLPMFSFTGSRGSFLGDLNFYG 489
Query: 482 RNGVDSYLQTKAV 494
+ G+ Y Q K V
Sbjct: 490 KAGIQFYTQWKTV 502
>At2g14170 [EG] KOG2449 Methylmalonate semialdehyde dehydrogenase
Length = 607
Score = 193 bits (490), Expect = 6e-49
Identities = 156/483 (32%), Positives = 231/483 (47%), Gaps = 26/483 (5%)
Query: 24 INNEFVKSSDGKKIESINPSTEESIVSFFAASEKDVNSAVTAARDAFENNWSKTSGEQRG 83
I FV+S I+ INP+T+E + + ++ +AV+AA+ AF W T R
Sbjct: 118 IGGSFVESQSSSFIDVINPATQEVVSKVPLTTNEEFKAAVSAAKQAFPL-WRNTPITTRQ 176
Query: 84 ILLSKLFDLIERDKLLLAAIETLDSGKPYHSNSLADLEQILQLTRYYAGGADKFTGGEYI 143
++ K +LI ++ LA T + GK +S D+ + L++ + G A GEY+
Sbjct: 177 RVMLKFQELIRKNMDKLAMNITTEQGKTL-KDSHGDIFRGLEVVEHACGMAT-LQMGEYL 234
Query: 144 P-LNQDKYAYTMKVPYGVVAQIVPWNYPLAMASWKIQSCLAAGNTIVIKPAENTSLSLLY 202
P ++ Y+++ P GV A I P+N+P + W + GNT ++KP+E + +
Sbjct: 235 PNVSNGVDTYSIREPLGVCAGICPFNFPAMIPLWMFPVAVTCGNTFILKPSEKDPGASVI 294
Query: 203 FAQLVKEAGFPPGVLNILPGYGSVTGTAMASHTDIDKIAFTGSTAVGQKVMSLAAQSNLK 262
A+L EAG P GVLNI+ G T A+ DI ++F GS G + + AA K
Sbjct: 295 LAELAMEAGLPDGVLNIVHGTND-TVNAICDDEDIRAVSFVGSNTAGMHIYARAAAKG-K 352
Query: 263 AVTLECGGKSPCLIFADANLDEAIPWVAGGIFYNSGQNCTANSRIYVHEDIYEEFLTKFE 322
+ G K+ L+ DAN+D + + F +GQ C A S + D + + K
Sbjct: 353 RIQSNMGAKNHGLVLPDANIDATLNALLAAGFGAAGQRCMALSTVVFVGDA-KSWEDKLV 411
Query: 323 EYAKSNWKFGAKFDPFDKDCTLGPVISKVQYDR----IQSYVEHGKASEKLGFKEFAEYP 378
E AK+ K +P D LGPVISK +R IQS V+ G G
Sbjct: 412 ERAKA-LKVTCGSEP---DADLGPVISKQAKERICRLIQSGVDDGAKLLLDGRDIVVPGY 467
Query: 379 SKGYFIPPTIFSDVPNSSKLSQEEIFGPVGVVASFSTYEEAIKLANDSSYGLASCVFSEN 438
KG FI PTI S V + +EEIFGPV V ++++EAI + N + YG + +F+ +
Sbjct: 468 EKGNFIGPTILSGVTPDMECYKEEIFGPVLVCMQANSFDEAISIINKNKYGNGAAIFTSS 527
Query: 439 ARTTAQFARDIRAGTVWINSSNDEEISVP-----FGGFKMSGIG--RELGRNGVDSYLQT 491
+F DI AG + IN I VP F G K S G G+ GVD + Q
Sbjct: 528 GAAARKFQMDIEAGQIGIN----VPIPVPLPFFSFTGNKASFAGDLNFYGKAGVDFFTQI 583
Query: 492 KAV 494
K V
Sbjct: 584 KTV 586
>Hs11095441 [EG] KOG2449 Methylmalonate semialdehyde dehydrogenase
Length = 535
Score = 189 bits (480), Expect = 8e-48
Identities = 137/485 (28%), Positives = 236/485 (48%), Gaps = 26/485 (5%)
Query: 22 LFINNEFVKSSDGKKIESINPSTEESIVSFFAASEKDVNSAVTAARDAFENNWSKTSGEQ 81
LFI +FV+S K I+ NP+T E I A++ ++++A+ + + AF W+ TS
Sbjct: 42 LFIGGKFVESKSDKWIDIHNPATNEVIGRVPQATKAEMDAAIASCKRAFPA-WADTSVLS 100
Query: 82 RGILLSKLFDLIERDKLLLAAIETLDSGKPYHSNSLADLEQILQLTRYYAGGADKFTGGE 141
R +L + LI+ + +A + TL+ GK +++ D+ + LQ+ + G
Sbjct: 101 RQQVLLRYQQLIKENLKEIAKLITLEQGKTL-ADAEGDVFRGLQVVEHACSVTSLMMGET 159
Query: 142 YIPLNQDKYAYTMKVPYGVVAQIVPWNYPLAMASWKIQSCLAAGNTIVIKPAENTSLSLL 201
+ +D Y+ ++P GV A I P+N+P + W + GNT ++KP+E + +
Sbjct: 160 MPSITKDMDLYSYRLPLGVCAGIAPFNFPAMIPLWMFPMAMVCGNTFLMKPSERVPGATM 219
Query: 202 YFAQLVKEAGFPPGVLNILPGYGSVTGTAMASHTDIDKIAFTGSTAVGQKVMSLAAQSNL 261
A+L++++G P G LNI+ G + H DI I+F GS G+ + ++
Sbjct: 220 LLAKLLQDSGAPDGTLNIIHGQHEAV-NFICDHPDIKAISFVGSNKAGEYIFERGSRHG- 277
Query: 262 KAVTLECGGKSPCLIFADANLDEAIPWVAGGIFYNSGQNCTA-NSRIYVHEDIYEEFLTK 320
K V G K+ ++ DAN + + + G F +GQ C A ++ + V E +++L +
Sbjct: 278 KRVQANMGAKNHGVVMPDANKENTLNQLVGAAFGAAGQRCMALSTAVLVGE--AKKWLPE 335
Query: 321 FEEYAKSNWKFGAKFDPFDKDCTLGPVISKVQYDRIQSYVEHGKASEKLGFKEFAEYPSK 380
E+AK N + A P LGP+I+ +R+ + ++ G + + K
Sbjct: 336 LVEHAK-NLRVNAGDQP---GADLGPLITPQAKERVCNLIDSGTKEGASILLDGRKIKVK 391
Query: 381 GY----FIPPTIFSDVPNSSKLSQEEIFGPVGVVASFSTYEEAIKLANDSSYGLASCVFS 436
GY F+ PTI S+V + +EEIFGPV VV T +EAI++ N++ YG + +F+
Sbjct: 392 GYENGNFVGPTIISNVKPNMTCYKEEIFGPVLVVLETETLDEAIQIVNNNPYGNGTAIFT 451
Query: 437 ENARTTAQFARDIRAGTVWINSSNDEEISVPFGGFKMSGIGREL-------GRNGVDSYL 489
N T ++A + G V +N I VP F +G G+ G+ Y
Sbjct: 452 TNGATARKYAHLVDVGQVGVN----VPIPVPLPMFSFTGSRSSFRGDTNFYGKQGIQFYT 507
Query: 490 QTKAV 494
Q K +
Sbjct: 508 QLKTI 512
>7290043 [EG] KOG2449 Methylmalonate semialdehyde dehydrogenase
Length = 552
Score = 187 bits (475), Expect = 3e-47
Identities = 145/484 (29%), Positives = 229/484 (46%), Gaps = 24/484 (4%)
Query: 22 LFINNEFVKSSDGKKIESINPSTEESIVSFFAASEKDVNSAVTAARDAFENNWSKTSGEQ 81
LFI+ +FV+S + I+ +P+T + + A++ ++ +A+ + + AF + WS S
Sbjct: 60 LFIDGKFVESKTNEWIDVHDPATNQVVTRVPKATQAEMQAALESNKKAFRS-WSNQSILT 118
Query: 82 RGILLSKLFDLIERDKLLLAAIETLDSGKPYHSNSLADLEQILQLTRYYAGGADKFTGGE 141
R ++ KL LI+ + LA T + GK +++ D+ + LQ+ + G
Sbjct: 119 RQQVMFKLQALIKENMGELAKNITKEQGKTL-ADAEGDVLRGLQVVEHCCSIPSLQMGET 177
Query: 142 YIPLNQDKYAYTMKVPYGVVAQIVPWNYPLAMASWKIQSCLAAGNTIVIKPAENTSLSLL 201
+ +D Y++ +P GV A + P+N+P + W + GNT+++KP+E + +
Sbjct: 178 VANVARDMDTYSLVLPLGVTAGVAPFNFPAMIPLWMFPVAITTGNTMLLKPSERVPGATM 237
Query: 202 YFAQLVKEAGFPPGVLNILPGYGSVTGTAMASHTDIDKIAFTGSTAVGQKVMSLAAQSNL 261
+L+ EAG PPGV+N++ G + +I ++F GS G+ + A + N
Sbjct: 238 LLMELLNEAGCPPGVVNVIHGQHDAVNF-ICDAPEIKAVSFVGSDQAGKYIYERAGK-NG 295
Query: 262 KAVTLECGGKSPCLIFADANLDEAIPWVAGGIFYNSGQNCTANSRIYVHEDIYEEFLTKF 321
K V G K+ +I DAN + + +AG F +GQ C A S D + ++
Sbjct: 296 KRVQSNMGAKNHGIILGDANKENTLNQLAGAAFGAAGQRCMALSTAVFVGDA-QAWIPDL 354
Query: 322 EEYAKSNWKFGAKFDPFDKDCTLGPVISKVQYDRIQSYVEHG-KASEKL---GFKEFAEY 377
E A+ K A P +GPVIS RI +E G K KL G K
Sbjct: 355 VERAQK-LKVNAGHVP---GTDVGPVISAASRQRINDLIESGVKEGAKLILDGRKITVPG 410
Query: 378 PSKGYFIPPTIFSDVPNSSKLSQEEIFGPVGVVASFSTYEEAIKLANDSSYGLASCVFSE 437
GYF+ PTI SDV S K EEIFGPV V+ T ++AI + N + YG + VF+
Sbjct: 411 YEDGYFVGPTILSDVTPSMKCYTEEIFGPVLVILKADTLDDAIGIVNANPYGNGTAVFTT 470
Query: 438 NARTTAQFARDIRAGTVWINSSNDEEISVPFGGFKMSGIGREL-------GRNGVDSYLQ 490
N +F +I AG V +N I VP F +G G+ G+ Y Q
Sbjct: 471 NGAAARKFVNEIDAGQVGVN----VPIPVPLPMFSFTGTRGSFRGDHHFYGKQGIKFYTQ 526
Query: 491 TKAV 494
TK V
Sbjct: 527 TKTV 530
>SPBC21C3.15c [C] KOG2454 Betaine aldehyde dehydrogenase
Length = 522
Score = 181 bits (460), Expect = 2e-45
Identities = 128/453 (28%), Positives = 216/453 (47%), Gaps = 21/453 (4%)
Query: 55 SEKDVNSAVTAARDAFENNWSKTSGEQRGILLSKLFDLIERDKLLLAAIETLDSGKPYHS 114
++ D++ ++ A +A + W TS +R L L + I R++ A I D+GK
Sbjct: 23 NKSDIDQSIILAEEA-QKEWKSTSFAERRNFLKALKENIIRNQDKYAEIACKDTGKTLVD 81
Query: 115 NSLADLEQILQLTRYYAGGADKFTGGEYIP---LNQDKYAYTMKVPYGVVAQIVPWNYPL 171
+ ++ L+ + ++ P L K Y P GV+A +V WNYPL
Sbjct: 82 AAFGEILVTLEKINWTLANGEQSLRPTKRPNSLLTSYKGGYVKYEPLGVIAALVSWNYPL 141
Query: 172 AMASWKIQSCLAAGNTIVIKPAENTSLSLLYFAQLVKEA----GFPPGVLNILPGYGSVT 227
A I S L AGN IV+K +E T+ S + ++V+ G P ++ + V
Sbjct: 142 HNALGPIISALFAGNAIVVKGSELTAWSTHQYCEMVRSLLQSMGHSPELVQCITCLPDVA 201
Query: 228 GTAMASHTDIDKIAFTGSTAVGQKVMSLAAQSNLKAVTLECGGKSPCLIFADANLDEAIP 287
+ SH+ I I F GS + K+++ +A L + LE GGK PC++ D L+E +
Sbjct: 202 DH-LTSHSGIKHITFIGSQPIA-KLVAASAAKQLTPLCLELGGKDPCILTDDHRLEEILS 259
Query: 288 WVAGGIFYNSGQNCTANSRIYVHEDIYEEFLTKFEEYAKSNWKFGAKFDPFDKDCTLGPV 347
V G+F ++GQNC RI + +Y+ +TK S + G D +G +
Sbjct: 260 IVMRGVFQSAGQNCIGIERIIALDGVYDTIITKLYNRI-STMRLGMY---TQNDVDMGAM 315
Query: 348 ISKVQYDRIQSYVEHG-KASEKLGFK----EFAEYPSKGYFIPPTIFSDVPNSSKLSQEE 402
+S ++D ++S ++ +L + + +YP YF+ PT+ D N K++QEE
Sbjct: 316 VSNNRFDHLESLIQDAVSKGARLVYGGHRFQHPKYPKGNYFL-PTLLVDATNEMKIAQEE 374
Query: 403 IFGPVGVVASFSTYEEAIKLANDSSYGLASCVFSENARTTAQFARDIRAGTVWINSSND- 461
F P+ +V + E A+++AN + +GL + VF + + F ++ G V +N
Sbjct: 375 CFAPIALVFRAKSPEHALEIANGTEFGLGASVFGRDKQLCQYFTDNLETGMVAVNDFGAF 434
Query: 462 EEISVPFGGFKMSGIGRELGRNGVDSYLQTKAV 494
+ +PFGG K SG GR G G+ +KA+
Sbjct: 435 YLLQMPFGGCKKSGYGRFAGYEGLRGICNSKAI 467
>CE01232 [C] KOG2453 Aldehyde dehydrogenase
Length = 514
Score = 178 bits (451), Expect = 2e-44
Identities = 135/499 (27%), Positives = 246/499 (49%), Gaps = 31/499 (6%)
Query: 20 LGLFINNEFVK----SSDGKKIESINPSTEESIVSFFAASEKDVNSAVTAARDAFENNWS 75
LGL NN V ++ G+ ++S P+ I + + +D A++ A+ A+ N+W
Sbjct: 18 LGLTENNAGVFHGKWAASGQVVQSFAPANNSPIANVQNGNVQDYEIAISEAKKAY-NDWC 76
Query: 76 KTSGEQRGILLSKLFDLIERDKLLLAAIETLDSGKPYHSNSLADLEQILQLTRYYAGGAD 135
+ +RG ++ ++ D + L + +L+ GK + + ++++ + + Y A G
Sbjct: 77 EVPAPRRGEIVRQIGDKLRTQLQNLGKLVSLEMGK-ISAEGVGEVQEYVDICDY-ATGLS 134
Query: 136 KFTGGEYIPLNQDKYAYTMKV-PYGVVAQIVPWNYPLAMASWKIQSCLAAGNTIVIKPAE 194
+ G+ P + +A + P GVV I +N+P A+ W L GN++V KPA
Sbjct: 135 RSLEGKIFPSERPGHALLEQWNPLGVVGVISAFNFPCAVYGWNNALALVTGNSVVWKPAP 194
Query: 195 NTSLSLLYFAQLVKEA----GFPPGVLNILPGYGSVTGTAMASHTDIDKIAFTGSTAVGQ 250
+T L+ + +LV+E P + +++ G G V G A+ ++ ++FTGS+ +G
Sbjct: 195 STPLTAIAVTKLVEEVLVANNVNPALCSLVCGEGDV-GQALVKDKRVNLVSFTGSSEIG- 252
Query: 251 KVMSLAAQSNLKAVTLECGGKSPCLIFADANLDEAIPWVAGGIFYNSGQNCTANSRIYVH 310
K++ Q+ + LE GG + ++ DA+L+ +P +GQ CT R+ VH
Sbjct: 253 KIVGQQVQARFGKLLLELGGNNAIIVNEDADLNMVVPATVFAAVGTAGQRCTTTRRLIVH 312
Query: 311 EDIYEEFLTKFEE-YAKSNWKFGAKFDPFDKDCTLGPVISKVQYDRIQSYVEHGKASEKL 369
+ +Y++ L + ++ YA+ + G P D + +GP+ ++ + ++ V AS
Sbjct: 313 DKVYDQVLERLKKAYAQFESRIGC---PLDSNTIIGPLHNQQAVGKYKASVAEAVAS--- 366
Query: 370 GFKEFAEYPSK-----GYFIPPTIFSDVPNSSKLSQEEIFGPVGVVASFSTYEEAIKLAN 424
G K EY K G F+ PTI + + + S + E F P+ V FST EEAI + N
Sbjct: 367 GGK--IEYGGKVLERDGNFVLPTIVTGLKHDSPVVLRETFAPILYVLKFSTLEEAIAINN 424
Query: 425 DSSYGLASCVFSENARTTAQF--ARDIRAGTVWIN-SSNDEEISVPFGGFKMSGIGRELG 481
+ GL+S +F+ N + ++ + G V +N ++ EI FGG K +G GRE G
Sbjct: 425 EVDQGLSSSLFTTNIQNVFKWMGPKGSDCGIVNVNIPTSGAEIGGAFGGEKETGGGRESG 484
Query: 482 RNGVDSYLQTKAVHVNIAK 500
+ Y++ +N +K
Sbjct: 485 SDSWRQYMRRSTCTINYSK 503
>CE13415 [C] KOG2456 Aldehyde dehydrogenase
Length = 437
Score = 166 bits (421), Expect = 6e-41
Identities = 129/439 (29%), Positives = 211/439 (47%), Gaps = 20/439 (4%)
Query: 63 VTAARDAFENNWSKTSGEQRGILLSKLFDLIERDKLLLAAIETLDSGKPYHSNSLADLEQ 122
+ A+ A+ N + E R L +L LIE ++ L + D + + +L
Sbjct: 6 IVEAQRAYFNTGATKPAEFRKEQLLQLKKLIEENRAALTEVVWKDLRRRHEVTEPMELGG 65
Query: 123 ILQLTRYYAGGADKFTGGEYIP-----LNQDKYAYTMKVPYGVVAQIVPWNYPLAMASWK 177
L+ YY D + Y+ L DK Y +K P GVV I PWNYP++M
Sbjct: 66 SLEEIAYYLKNLDDWMKPTYVEPTVATLPTDK-PYIVKDPKGVVLVISPWNYPVSMVLLP 124
Query: 178 IQSCLAAGNTIVIKPAENTSLSLLYFAQLVKEAGFPPGVLNILPGYGSVTGTAMASHTDI 237
+ +AAGNTIVIKP+E + + + F +L+ + F P + I+ G + T
Sbjct: 125 MIPSIAAGNTIVIKPSELSENTAILFEKLIPKY-FDPKYVTIV--NGGIPETTELLKERF 181
Query: 238 DKIAFTGSTAVGQKVMSLAAQSNLKAVTLECGGKSPCLIFADANLDEAIPWVAGGIFYNS 297
D I +TG V + +M+ AA+ +L VTLE GGK P ++ DA+++ + +A G + N
Sbjct: 182 DHIIYTGCPPVAKIIMAAAAK-HLTPVTLELGGKCPVVVEDDADIEISAQRIARGKWLNC 240
Query: 298 GQNCTANSRIYVHEDIYEEFLTKFEEYAKSNWKFGAKFDPFDKDCTLGPVISKVQYDRIQ 357
GQ C A I V +F+ ++ K + AK + VI++ +DRI
Sbjct: 241 GQTCLAPDYILVSSATKPKFVAAIQKCLKEFYGGNAK-----ESKDYSRVINQRHFDRIS 295
Query: 358 SYVEHGKASEKLGFKEFAEYPSKGYFIPPTIFSDVPNSSKLSQEEIFGPVGVVASFSTYE 417
+ ++ K G +E + + FIPPT+ DV + +EIFGPV + +
Sbjct: 296 ALLDESKGVVLAGNEESRDRSDR--FIPPTVL-DVEKTDPFMHDEIFGPVLPIITVKNLC 352
Query: 418 EAIKLANDSSYGLASCVFSENARTTAQFARDIRAGTVWINS--SNDEEISVPFGGFKMSG 475
E+I N LA+ +F+++ +F + +G V +N + I++PFGG +SG
Sbjct: 353 ESIDFINKGEKPLAAYIFTKDEAKVQRFLNETTSGGVTVNDVIMHVAVITLPFGGVGVSG 412
Query: 476 IGRELGRNGVDSYLQTKAV 494
+GR G+ G D++ K+V
Sbjct: 413 MGRYRGKFGFDTFTHEKSV 431
>Hs4557343 [C] KOG2453 Aldehyde dehydrogenase
Length = 511
Score = 163 bits (413), Expect = 5e-40
Identities = 132/506 (26%), Positives = 233/506 (45%), Gaps = 19/506 (3%)
Query: 6 TVNIPQLNITYEQPLGLFINNEFVKSSD----GKKIESINPSTEESIVSFFAASEKDVNS 61
T+ I Q + + LGL NE V + G+ I + P+ E I AS D
Sbjct: 3 TLLINQPQYAWLKELGLREENEGVYNGSWGGRGEVITTYCPANNEPIARVRQASVADYEE 62
Query: 62 AVTAARDAFENNWSKTSGEQRGILLSKLFDLIERDKLLLAAIETLDSGKPYHSNSLADLE 121
V AR+A++ W+ +RG ++ ++ D + +L ++ +L+ GK + +++
Sbjct: 63 TVKKAREAWKI-WADIPAPKRGEIVRQIGDALREKIQVLGSLVSLEMGKIL-VEGVGEVQ 120
Query: 122 QILQLTRYYAGGADKFTGGEYIPLNQDKYAYTMKV-PYGVVAQIVPWNYPLAMASWKIQS 180
+ + + Y A G + GG +P + +A + P G+V I +N+P+A+ W
Sbjct: 121 EYVDICDY-AVGLSRMIGGPILPSERSGHALIEQWNPVGLVGIITAFNFPVAVYGWNNAI 179
Query: 181 CLAAGNTIVIKPAENTSLSLLYFAQLVK---EAGFPPGVLNILPGYGSVTGTAMASHTDI 237
+ GN + K A TSL + +++ E PG + L G+ GTAMA +
Sbjct: 180 AMICGNVCLWKGAPTTSLISVAVTKIIAKVLEDNKLPGAICSLTCGGADIGTAMAKDERV 239
Query: 238 DKIAFTGSTAVGQKVMSLAAQSNLKAVTLECGGKSPCLIFADANLDEAIPWVAGGIFYNS 297
+ ++FTGST VG++V L Q LE GG + + F DA+L +P +
Sbjct: 240 NLLSFTGSTQVGKQV-GLMVQERFGRSLLELGGNNAIIAFEDADLSLVVPSALFAAVGTA 298
Query: 298 GQNCTANSRIYVHEDIYEEFLTKFEEYAKSNWKFGAKFDPFDKDCTLGPVISKVQYDRIQ 357
GQ CT R+++HE I++E + + ++ A + + G +P+D + GP+ +K
Sbjct: 299 GQRCTTARRLFIHESIHDEVVNRLKK-AYAQIRVG---NPWDPNVLYGPLHTKQAVSMFL 354
Query: 358 SYVEHGKASEKLGFKEFAEYPSKGYFIPPTIFSDVPNSSKLSQEEIFGPVGVVASFSTYE 417
VE K G ++ PTI + + + + ++ E F P+ V F E
Sbjct: 355 GAVEEAKKEGGTVVYGGKVMDRPGNYVEPTIVTGLGHDASIAHTETFAPILYVFKFKNEE 414
Query: 418 EAIKLANDSSYGLASCVFSENARTTAQF--ARDIRAGTVWIN-SSNDEEISVPFGGFKMS 474
E N+ GL+S +F+++ ++ + G V +N ++ EI FGG K +
Sbjct: 415 EVFAWNNEVKQGLSSSIFTKDLGRIFRWLGPKGSDCGIVNVNIPTSGAEIGGAFGGEKHT 474
Query: 475 GIGRELGRNGVDSYLQTKAVHVNIAK 500
G GRE G + Y++ +N +K
Sbjct: 475 GGGRESGSDAWKQYMRRSTCTINYSK 500
>YHR039c [C] KOG1772 Vacuolar H+-ATPase V1 sector subunit G
Length = 644
Score = 157 bits (398), Expect = 3e-38
Identities = 126/475 (26%), Positives = 218/475 (45%), Gaps = 26/475 (5%)
Query: 42 PSTEESIVSFFAASEKDVNSAVTAARDAFENNWSKTSGEQRGILLSKLFDLIERDKLLLA 101
P+T + + SF + +E D++ V+ A A ++ W + +R +L+ L D I ++ L+A
Sbjct: 117 PATGQYLGSFPSKTEADIDEMVSKAGKA-QSTWGNSDFSRRLRVLASLHDYILNNQDLIA 175
Query: 102 AIETLDSGKPYHSNSLADLEQILQLTRYYAGGADKFTGGEYIP------LNQDKYAYTMK 155
+ DSGK S+ ++ L+ ++ + P + K A
Sbjct: 176 RVACRDSGKTMLDASMGEILVTLEKIQWTIKHGQRALQPSRRPGPTNFFMKWYKGAEIRY 235
Query: 156 VPYGVVAQIVPWNYPLAMASWKIQSCLAAGNTIVIKPAENTSLSLLYFAQLVKEA----G 211
P GV++ IV WNYP I + L GN IV+K +E S +F +L+++
Sbjct: 236 EPLGVISSIVSWNYPFHNLLGPIIAALFTGNAIVVKCSEQVVWSSEFFVELIRKCLEACD 295
Query: 212 FPPGVLNIL----PGYGSVTGTAMASHTDIDKIAFTGSTAVGQKVMSLAAQSNLKAVTLE 267
P ++ + P + SH I F GS V ++ AA+S L V +E
Sbjct: 296 EDPDLVQLCYCLPPTENDDSANYFTSHPGFKHITFIGSQPVAHYILKCAAKS-LTPVVVE 354
Query: 268 CGGKSPCLIFADA-NLDEAIPWVAGGIFYNSGQNCTANSRIYVHEDIYEEFLTKFEEYAK 326
GGK ++ A NLD + G F +SGQNC R+ V ++ Y++ + +
Sbjct: 355 LGGKDAFIVLDSAKNLDALSSIIMRGTFQSSGQNCIGIERVIVSKENYDDLVKILNDRMT 414
Query: 327 SN-WKFGAKFDPFDKDCTLGPVISKVQYDRIQSYVEHGKASEKL---GFKEFA--EYPSK 380
+N + G+ D + + +G +IS ++D +++ V+ A G F +YP +
Sbjct: 415 ANPLRQGSDIDHLE-NVDMGAMISDNRFDELEALVKDAVAKGARLLQGGSRFKHPKYP-Q 472
Query: 381 GYFIPPTIFSDVPNSSKLSQEEIFGPVGVVASFSTYEEAIKLANDSSYGLASCVFSENAR 440
G++ PT+ DV K++Q E+FGP+ V+ + ++LAN + +GL VF + +
Sbjct: 473 GHYFQPTLLVDVTPEMKIAQNEVFGPILVMMKAKNTDHCVQLANSAPFGLGGSVFGADIK 532
Query: 441 TTAQFARDIRAGTVWINS-SNDEEISVPFGGFKMSGIGRELGRNGVDSYLQTKAV 494
A ++ G V IN + +PFGG SG G+ G G+ K+V
Sbjct: 533 ECNYVANSLQTGNVAINDFATFYVCQLPFGGINGSGYGKFGGEEGLLGLCNAKSV 587
>At1g54100 [C] KOG2453 Aldehyde dehydrogenase
Length = 508
Score = 156 bits (394), Expect = 8e-38
Identities = 122/486 (25%), Positives = 224/486 (45%), Gaps = 20/486 (4%)
Query: 20 LGLFINNEFVKSSDGKKIESINPSTEESIVSFFAASEKDVNSAVTAARDAFENNWSKTSG 79
LG ++ ++ ++G + ++NP+ + I AS +D + A +A + W + +
Sbjct: 21 LGSYVAGKW--QANGPLVSTLNPANNQPIAQVVEASLEDYEQGLKACEEAAKI-WMQVTA 77
Query: 80 EQRGILLSKLFDLIERDKLLLAAIETLDSGKPYHSNSLADLEQILQLTRYYAGGADKFTG 139
+RG ++ ++ D + L + +L+ GK + + ++++++ + + A G +
Sbjct: 78 PKRGDIVRQIGDALRSKLDYLGRLLSLEMGKIL-AEGIGEVQEVIDMCDF-AVGLSRQLN 135
Query: 140 GEYIPLNQDKYAYT-MKVPYGVVAQIVPWNYPLAMASWKIQSCLAAGNTIVIKPAENTSL 198
G IP + + M P G+V I +N+P A+ W L GN +V K A T L
Sbjct: 136 GSVIPSERPNHMMLEMWNPLGIVGVITAFNFPCAVLGWNACIALVCGNCVVWKGAPTTPL 195
Query: 199 SLLYFAQLVKEA----GFPPGVLNILPGYGSVTGTAMASHTDIDKIAFTGSTAVGQKVMS 254
+ +LV E P + + G G+ G A+A T I ++FTGS+ VG V
Sbjct: 196 ITIAMTKLVAEVLEKNNLPGAIFTAMCG-GAEIGEAIAKDTRIPLVSFTGSSRVGSMVQQ 254
Query: 255 LAAQSNLKAVTLECGGKSPCLIFADANLDEAIPWVAGGIFYNSGQNCTANSRIYVHEDIY 314
+ K + LE G + ++ DA++ A V +GQ CT R+ +HE +Y
Sbjct: 255 TVNARSGKTL-LELSGNNAIIVMDDADIQLAARSVLFAAVGTAGQRCTTCRRLLLHESVY 313
Query: 315 EEFLTKFEEYAKSNWKFGAKFDPFDKDCTLGPVISKVQYDRIQSYVEHGKASEKLGFKEF 374
++ L E +++K +P +K LGP+ + + +E K+
Sbjct: 314 DKVL----EQLLTSYKQVKIGNPLEKGTLLGPLHTPESKKNFEKGIEVIKSQGGKILTGG 369
Query: 375 AEYPSKGYFIPPTIFSDVPNSSKLSQEEIFGPVGVVASFSTYEEAIKLANDSSYGLASCV 434
+G F+ PTI ++ + + +EE+F PV V F ++ EA+ + N GL+S +
Sbjct: 370 KAVEGEGNFVEPTII-EISADAAVVKEELFAPVLYVLKFKSFGEAVAINNSVPQGLSSSI 428
Query: 435 FSENARTTAQFARDIRA--GTVWIN-SSNDEEISVPFGGFKMSGIGRELGRNGVDSYLQT 491
F+ N ++ + + G V +N +N EI FGG K +G GRE G + Y++
Sbjct: 429 FTRNPENIFRWIGPLGSDCGIVNVNIPTNGAEIGGAFGGEKATGGGREAGSDSWKQYMRR 488
Query: 492 KAVHVN 497
+N
Sbjct: 489 STCTIN 494
>HsM4502035 [C] KOG2456 Aldehyde dehydrogenase
Length = 453
Score = 155 bits (391), Expect = 2e-37
Identities = 131/442 (29%), Positives = 203/442 (45%), Gaps = 35/442 (7%)
Query: 59 VNSAVTAARDAFENNWSKTSGEQRGILLSKLFDLIERDKLLLAAIETLDSGKPYHSNSLA 118
++ AV AR AF + ++ + R L L LI+ + L D K +
Sbjct: 4 ISEAVKRARAAFSSGRTRPL-QFRFQQLEALQRLIQEQEQELVGALAADLHKNEWNAYYE 62
Query: 119 DLEQILQLTRYYAGGADKFTGGEYI---PLNQDKYAYTMKVPYGVVAQIVPWNYPLAMAS 175
++ +L+ Y ++ E + P Q Y P GVV I WNYP +
Sbjct: 63 EVVYVLEEIEYMIQKLPEWAADEPVEKTPQTQQDELYIHSEPLGVVLVIGTWNYPFNLTI 122
Query: 176 WKIQSCLAAGNTIVIKPAENT----SLSLLYFAQLVKEAGFPPGVLNILPGYGSVTGTAM 231
+ +AAGN +V+KP+E + SL Q + + +P V+N G V T
Sbjct: 123 QPMVGAIAAGNAVVLKPSELSENMASLLATIIPQYLDKDLYP--VIN-----GGVPETTE 175
Query: 232 ASHTDIDKIAFTGSTAVGQKVMSLAAQSNLKAVTLECGGKSPCLIFADANLDEAIPWVAG 291
D I +TGST VG+ +M+ AA+ +L VTLE GGKSPC + + +LD A +A
Sbjct: 176 LLKERFDHILYTGSTGVGKIIMTAAAK-HLTPVTLELGGKSPCYVDKNCDLDVACRRIAW 234
Query: 292 GIFYNSGQNCTANSRIYVHEDIYEEFLTKFEEYAKSNWKFGAKFDPFDKDCTLGPVISKV 351
G F NSGQ C A I I + + K ++ K + AK K G +IS
Sbjct: 235 GKFMNSGQTCVAPDYILCDPSIQNQIVEKLKKSLKEFYGEDAK-----KSRDYGRIISAR 289
Query: 352 QYDRIQSYVEHGKASEKLGFKEFAEYPSKGYFIPPTIFSDVPNSSKLSQEEIFGPVGVVA 411
+ R+ +E +K+ + + ++ +I PTI +DV S + QEEIFGPV +
Sbjct: 290 HFQRVMGLIE----GQKVAYGGTGDAATR--YIAPTILTDVDPQSPVMQEEIFGPVLPIV 343
Query: 412 SFSTYEEAIKLANDSSYGLASCVFSENARTTAQFARDIRAGTVWINSSNDEEI-----SV 466
+ EEAI+ N LA +FS N + + + +G V ++ND + S+
Sbjct: 344 CVRSLEEAIQFINQREKPLALYMFSSNDKVIKKMIAETSSGGV---AANDVIVHITLHSL 400
Query: 467 PFGGFKMSGIGRELGRNGVDSY 488
PFGG SG+G G+ +++
Sbjct: 401 PFGGVGNSGMGSYHGKKSFETF 422
>7293810 [C] KOG2453 Aldehyde dehydrogenase
Length = 594
Score = 155 bits (391), Expect = 2e-37
Identities = 125/501 (24%), Positives = 229/501 (44%), Gaps = 20/501 (3%)
Query: 9 IPQLNITYEQPLGLFINNEFVKSSD----GKKIESINPSTEESIVSFFAASEKDVNSAVT 64
I Q ++ + LGL +N V S G + S +P T + I + +++ +
Sbjct: 86 IDQPEYSFLKELGLERDNPGVYSGQWQGRGPSVTSYDPGTGQPIAKVRQGNVQELEHTIG 145
Query: 65 AARDAFENNWSKTSGEQRGILLSKLFDLIERDKLLLAAIETLDSGKPYHSNSLADLEQIL 124
A +A++ W + RG ++ ++ D + + K L + +L+ GK Y S ++++ +
Sbjct: 146 LAVEAYKQ-WRQVPAPVRGEIVRQIGDELRKYKEPLGKLVSLEVGKIY-SEGQGEVQEFI 203
Query: 125 QLTRYYAGGADKFTGGEYIPLNQDKYAYTMKVPYGVVAQIVPWNYPLAMASWKIQSCLAA 184
+ Y G + ++G D P GVV I +N+P A+ W L
Sbjct: 204 DICDYAVGLSRIYSGQLINSERADHSILEAWRPLGVVGVISAYNFPNAVFGWNAAIALTT 263
Query: 185 GNTIVIKPAENTSLSLLYFAQLVKEA----GFPPGVLNILPGYGSVTGTAMASHTDIDKI 240
GN+++ K A +T L + ++V E PP V+ + G G+ G + + ++ +
Sbjct: 264 GNSVLWKGAPSTPLVSVATTKIVAEVLRRNNLPP-VVTLCQG-GTDVGQTLVADKRVNLV 321
Query: 241 AFTGSTAVGQKVMSLAAQSNLKAVTLECGGKSPCLIFADANLDEAIPWVAGGIFYNSGQN 300
+FTGS G+ V + Q V LE GG + +I AN+ A+ G SGQ
Sbjct: 322 SFTGSCQTGRDV-GVEVQRRFGKVILELGGNNALIIDESANVKMALDAALFGCIGTSGQR 380
Query: 301 CTANSRIYVHEDIYEEFLTKFE-EYAKSNWKFGAKFDPFDKDCTLGPVISKVQYDRIQSY 359
CT RI VHE ++++F+ + +Y + K G + + +GPV ++ + ++
Sbjct: 381 CTTTRRIIVHEKLHDQFVKELVGKYKQLISKIGHQLEA---QTLVGPVHTQQNVENYKAA 437
Query: 360 VEHGKASEKLGFKEFAEYPSKGYFIPPTIFSDVPNSSKLSQEEIFGPVGVVASFSTYEEA 419
+ K+ G+++ PT+ + +P+ + + E F P+ + ++A
Sbjct: 438 IAEAKSLGGTVAFGGNVIQRDGFYVEPTVITGLPHDASVVHRETFAPIVYILKAKNVDQA 497
Query: 420 IKLANDSSYGLASCVFSENARTTAQF--ARDIRAGTVWIN-SSNDEEISVPFGGFKMSGI 476
I+ N+ GL+S +F+EN ++ A+ G V IN ++N EI FGG K +G
Sbjct: 498 IEWNNEVEQGLSSAIFTENIGQAFKWIGAKGSDCGIVNINTTTNGAEIGGAFGGEKATGG 557
Query: 477 GRELGRNGVDSYLQTKAVHVN 497
GRE G + Y + + VN
Sbjct: 558 GRESGSDAWKQYCKRATITVN 578
>Hs21359829 [C] KOG2456 Aldehyde dehydrogenase
Length = 453
Score = 154 bits (390), Expect = 2e-37
Identities = 131/442 (29%), Positives = 203/442 (45%), Gaps = 35/442 (7%)
Query: 59 VNSAVTAARDAFENNWSKTSGEQRGILLSKLFDLIERDKLLLAAIETLDSGKPYHSNSLA 118
++ AV AR AF + ++ + R L L LI+ + L D K +
Sbjct: 4 ISEAVKRARAAFSSGRTRPL-QFRIQQLEALQRLIQEQEQELVGALAADLHKNEWNAYYE 62
Query: 119 DLEQILQLTRYYAGGADKFTGGEYI---PLNQDKYAYTMKVPYGVVAQIVPWNYPLAMAS 175
++ +L+ Y ++ E + P Q Y P GVV I WNYP +
Sbjct: 63 EVVYVLEEIEYMIQKLPEWAADEPVEKTPQTQQDELYIHSEPLGVVLVIGTWNYPFNLTI 122
Query: 176 WKIQSCLAAGNTIVIKPAENT----SLSLLYFAQLVKEAGFPPGVLNILPGYGSVTGTAM 231
+ +AAGN +V+KP+E + SL Q + + +P V+N G V T
Sbjct: 123 QPMVGAIAAGNAVVLKPSELSENMASLLATIIPQYLDKDLYP--VIN-----GGVPETTE 175
Query: 232 ASHTDIDKIAFTGSTAVGQKVMSLAAQSNLKAVTLECGGKSPCLIFADANLDEAIPWVAG 291
D I +TGST VG+ +M+ AA+ +L VTLE GGKSPC + + +LD A +A
Sbjct: 176 LLKERFDHILYTGSTGVGKIIMTAAAK-HLTPVTLELGGKSPCYVDKNCDLDVACRRIAW 234
Query: 292 GIFYNSGQNCTANSRIYVHEDIYEEFLTKFEEYAKSNWKFGAKFDPFDKDCTLGPVISKV 351
G F NSGQ C A I I + + K ++ K + AK K G +IS
Sbjct: 235 GKFMNSGQTCVAPDYILCDPSIQNQIVEKLKKSLKEFYGEDAK-----KSRDYGRIISAR 289
Query: 352 QYDRIQSYVEHGKASEKLGFKEFAEYPSKGYFIPPTIFSDVPNSSKLSQEEIFGPVGVVA 411
+ R+ +E +K+ + + ++ +I PTI +DV S + QEEIFGPV +
Sbjct: 290 HFQRVMGLIE----GQKVAYGGTGDAATR--YIAPTILTDVDPQSPVMQEEIFGPVLPIV 343
Query: 412 SFSTYEEAIKLANDSSYGLASCVFSENARTTAQFARDIRAGTVWINSSNDEEI-----SV 466
+ EEAI+ N LA +FS N + + + +G V ++ND + S+
Sbjct: 344 CVRSLEEAIQFINQREKPLALYMFSSNDKVIKKMIAETSSGGV---AANDVIVHITLHSL 400
Query: 467 PFGGFKMSGIGRELGRNGVDSY 488
PFGG SG+G G+ +++
Sbjct: 401 PFGGVGNSGMGSYHGKKSFETF 422
>CE27441 [C] KOG2456 Aldehyde dehydrogenase
Length = 493
Score = 147 bits (370), Expect = 5e-35
Identities = 115/418 (27%), Positives = 197/418 (46%), Gaps = 27/418 (6%)
Query: 86 LSKLFDLIERDKLLLAAIETLDSGKPYHSNSLADLEQILQLTRYYAGGADKFTGGEYIPL 145
L KL IE ++ L+ D + + S + ++ +Q Y+ D + P
Sbjct: 29 LLKLKKFIEENREALSEAVWKDLRRRHESTEILEIGMTIQEIDYFLKNIDDWVK----PT 84
Query: 146 NQDKYAYTM-------KVPYGVVAQIVPWNYPLAMASWKIQSCLAAGNTIVIKPAENTSL 198
+ +K T K P GVV I PWNYP++M + +AAGNT+VIKP+E +
Sbjct: 85 HVEKTFTTALDKPVIEKDPKGVVLIISPWNYPVSMILLPMVPAIAAGNTVVIKPSELSEN 144
Query: 199 SLLYFAQLVKEAGFPPGVLNILPGYGSVTGTAMASHTDIDKIAFTGSTAVGQKVMSLAAQ 258
F +L+ + F + ++ G + T D I +TG V + +M+ AA+
Sbjct: 145 VAATFEKLIPKY-FESKYVTVVNG--GIPETTDLLKERFDHILYTGCPPVAKIIMTAAAK 201
Query: 259 SNLKAVTLECGGKSPCLIFADANLDEAIPWVAGGIFYNSGQNCTANSRIYVHEDIYEEFL 318
+L VTLE GGK P ++ DA++D + +A G + N GQ C A I V+ + + +
Sbjct: 202 -HLTPVTLELGGKCPVVVEDDADIDISAKRIAWGKWLNCGQTCLAPDYILVNSTVKPKLV 260
Query: 319 TKFEEYAKSNWKFGAKFDPFDKDCTLGPVISKVQYDRIQSYVEHGKASEKLGFKEFAEYP 378
+Y +F + KD +I++ +DRI ++ + + +G E
Sbjct: 261 AAIRKYVN---EFYGEDVKASKD--YARMINQRHFDRISGLLDKTQGAVLIG----GERD 311
Query: 379 SKGYFIPPTIFSDVPNSSKLSQEEIFGPVGVVASFSTYEEAIKLANDSSYGLASCVFSEN 438
+IPPT+ DV S +EIFGPV + + ++ E+++ D LA+ +F+ N
Sbjct: 312 RADLYIPPTVL-DVEKSDPFMHDEIFGPVLPIITVQSFSESLEYIADGEKPLAAYIFTRN 370
Query: 439 ARTTAQFARDIRAGTVWINS--SNDEEISVPFGGFKMSGIGRELGRNGVDSYLQTKAV 494
+ + +G V +N + ++PFGG +SG+GR G+ G D++ K+V
Sbjct: 371 EAKVKRLLNETSSGGVTVNDVLMHITVDTLPFGGVGVSGMGRYRGKYGFDTFTHEKSV 428
>Hs4557303 [C] KOG2456 Aldehyde dehydrogenase
Length = 485
Score = 144 bits (364), Expect = 2e-34
Identities = 110/343 (32%), Positives = 162/343 (47%), Gaps = 23/343 (6%)
Query: 151 AYTMKVPYGVVAQIVPWNYPLAMASWKIQSCLAAGNTIVIKPAENTSLSLLYFAQLVKEA 210
AY P GVV I WNYP + + +AAGN ++IKP+E + + A+L+ +
Sbjct: 95 AYIQPQPLGVVLIIGAWNYPFVLTIQPLIGAIAAGNAVIIKPSELSENTAKILAKLLPQ- 153
Query: 211 GFPPGVLNILPGYGSVTGTAMASHTDIDKIAFTGSTAVGQKVMSLAAQSNLKAVTLECGG 270
+ L I+ G V T D I +TG+TAVG+ VM AA+ +L VTLE GG
Sbjct: 154 -YLDQDLYIVIN-GGVEETTELLKQRFDHIFYTGNTAVGKIVMEAAAK-HLTPVTLELGG 210
Query: 271 KSPCLIFADANLDEAIPWVAGGIFYNSGQNCTANSRIYVHEDIYEEFLTKFEEYAKSNWK 330
KSPC I D +LD + G + N GQ C A I + + + K +E K +
Sbjct: 211 KSPCYIDKDCDLDIVCRRITWGKYMNCGQTCIAPDYILCEASLQNQIVWKIKETVKEFYG 270
Query: 331 FGAKFDPFDKDCTLGPVISKVQYDRIQSYVEHGKASEKLGFKEFAEYPSKGYFIPPTIFS 390
K P +I+ + RI S +E +K+ F E +I PT+ +
Sbjct: 271 ENIKESP-----DYERIINLRHFKRILSLLE----GQKIAFG--GETDEATRYIAPTVLT 319
Query: 391 DVPNSSKLSQEEIFGPVGVVASFSTYEEAIKLANDSSYGLASCVFSENARTTAQFARDIR 450
DV +K+ QEEIFGP+ + +EAI N+ LA VFS N + + +
Sbjct: 320 DVDPKTKVMQEEIFGPILPIVPVKNVDEAINFINEREKPLALYVFSHNHKLIKRMIDETS 379
Query: 451 AGTVWINSSNDEEI-----SVPFGGFKMSGIGRELGRNGVDSY 488
+G V + ND + S PFGG SG+G G++ D++
Sbjct: 380 SGGV---TGNDVIMHFTLNSFPFGGVGSSGMGAYHGKHSFDTF 419
>Hs18603595 [C] KOG2456 Aldehyde dehydrogenase
Length = 508
Score = 144 bits (364), Expect = 2e-34
Identities = 110/343 (32%), Positives = 162/343 (47%), Gaps = 23/343 (6%)
Query: 151 AYTMKVPYGVVAQIVPWNYPLAMASWKIQSCLAAGNTIVIKPAENTSLSLLYFAQLVKEA 210
AY P GVV I WNYP + + +AAGN ++IKP+E + + A+L+ +
Sbjct: 95 AYIQPQPLGVVLIIGAWNYPFVLTIQPLIGAIAAGNAVIIKPSELSENTAKILAKLLPQ- 153
Query: 211 GFPPGVLNILPGYGSVTGTAMASHTDIDKIAFTGSTAVGQKVMSLAAQSNLKAVTLECGG 270
+ L I+ G V T D I +TG+TAVG+ VM AA+ +L VTLE GG
Sbjct: 154 -YLDQDLYIVIN-GGVEETTELLKQRFDHIFYTGNTAVGKIVMEAAAK-HLTPVTLELGG 210
Query: 271 KSPCLIFADANLDEAIPWVAGGIFYNSGQNCTANSRIYVHEDIYEEFLTKFEEYAKSNWK 330
KSPC I D +LD + G + N GQ C A I + + + K +E K +
Sbjct: 211 KSPCYIDKDCDLDIVCRRITWGKYMNCGQTCIAPDYILCEASLQNQIVWKIKETVKEFYG 270
Query: 331 FGAKFDPFDKDCTLGPVISKVQYDRIQSYVEHGKASEKLGFKEFAEYPSKGYFIPPTIFS 390
K P +I+ + RI S +E +K+ F E +I PT+ +
Sbjct: 271 ENIKESP-----DYERIINLRHFKRILSLLE----GQKIAFG--GETDEATRYIAPTVLT 319
Query: 391 DVPNSSKLSQEEIFGPVGVVASFSTYEEAIKLANDSSYGLASCVFSENARTTAQFARDIR 450
DV +K+ QEEIFGP+ + +EAI N+ LA VFS N + + +
Sbjct: 320 DVDPKTKVMQEEIFGPILPIVPVKNVDEAINFINEREKPLALYVFSHNHKLIKRMIDETS 379
Query: 451 AGTVWINSSNDEEI-----SVPFGGFKMSGIGRELGRNGVDSY 488
+G V + ND + S PFGG SG+G G++ D++
Sbjct: 380 SGGV---TGNDVIMHFTLNSFPFGGVGSSGMGAYHGKHSFDTF 419
>At1g44170 [C] KOG2456 Aldehyde dehydrogenase
Length = 484
Score = 140 bits (353), Expect = 4e-33
Identities = 114/443 (25%), Positives = 212/443 (47%), Gaps = 18/443 (4%)
Query: 58 DVNSAVTAARDAFENNWSKTSGEQRGILLSKLFDLIERDKLLLAAIETLDSGKPYHSNSL 117
+ ++ VT R +F++ ++ E R L KL + + + + A D GKP +S+
Sbjct: 11 EASNLVTELRRSFDDGVTR-GYEWRVTQLKKLMIICDNHEPEIVAALRDDLGKPELESSV 69
Query: 118 ADLEQILQLTRYYAGGADKFTGGEYIPLNQDKYAYTMKV---PYGVVAQIVPWNYPLAMA 174
++ + + + E + + + ++ P GVV I WNYP ++
Sbjct: 70 YEVSLLRNSIKLALKQLKNWMAPEKAKTSLTTFPASAEIVSEPLGVVLVISAWNYPFLLS 129
Query: 175 SWKIQSCLAAGNTIVIKPAENTSLSLLYFAQLVKEAGFPPGVLNILPGYGSVTGTAMASH 234
+ ++AGN +V+KP+E S +L+++ P V + G+VT T+
Sbjct: 130 IDPVIGAISAGNAVVLKPSELAPASSALLTKLLEQYLDPSAVRVV---EGAVTETSALLE 186
Query: 235 TDIDKIAFTGSTAVGQKVMSLAAQSNLKAVTLECGGKSPCLIFADANLDEAIPWVAGGIF 294
DKI +TGS+ +G+ +M+ AA+ +L V LE GGKSP ++ +D +L + + G +
Sbjct: 187 QKWDKIFYTGSSKIGRVIMAAAAK-HLTPVVLELGGKSPVVVDSDTDLKVTVRRIIVGKW 245
Query: 295 -YNSGQNCTANSRIYVHEDIYEEFLTKFEEYAKSNWKFGAKFDPFDKDCTLGPVISKVQY 353
N+GQ C + I ++ + + + + KF K KD + +++ +
Sbjct: 246 GCNNGQACVSPDYILTTKEYAPKLIDAMKLELE---KFYGKNPIESKD--MSRIVNSNHF 300
Query: 354 DRIQSYVEHGKASEKLGFKEFAEYPSKGYFIPPTIFSDVPNSSKLSQEEIFGPVGVVASF 413
DR+ ++ + S+K+ + E + I PTI DVP S + EEIFGP+ + +
Sbjct: 301 DRLSKLLDEKEVSDKIVYG--GEKDRENLKIAPTILLDVPLDSLIMSEEIFGPLLPILTL 358
Query: 414 STYEEAIKLANDSSYGLASCVFSENARTTAQFARDIRAGTVWIN--SSNDEEISVPFGGF 471
+ EE+ + LA+ +F+ N + +FA + AG + +N + + ++PFGG
Sbjct: 359 NNLEESFDVIRSRPKPLAAYLFTHNKKLKERFAATVSAGGIVVNDIAVHLALHTLPFGGV 418
Query: 472 KMSGIGRELGRNGVDSYLQTKAV 494
SG+G G+ D++ KAV
Sbjct: 419 GESGMGAYHGKFSFDAFSHKKAV 441
>CE29047 [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrogenase
Length = 563
Score = 137 bits (345), Expect = 4e-32
Identities = 128/464 (27%), Positives = 206/464 (43%), Gaps = 30/464 (6%)
Query: 38 ESINPSTEESIVSFFA-ASEKDVNSAVTAARDAFENNWSKTSGEQRGILLSKLFDLIE-R 95
+ + PS S ++ + A+ + + A+ A A W + ++R +L + DL +
Sbjct: 80 KQVIPSDHRSTLAKYTYATGEQIQEAIDVALQA-RGAWERKPLKERAEILLRAADLAAGK 138
Query: 96 DKLLLAAIETLDSGKPYHSNSLADLEQILQLTRYYAGGADKFTGGEYIPLNQDKYAYTMK 155
++ L A L GK + +++ R+ A A + E I K +
Sbjct: 139 YRMKLNASTMLGQGKNIIQAEIDAACELIDFFRFNAVFAMELEHYEPISTKITKNTMQFR 198
Query: 156 VPYGVVAQIVPWNYPLAMASWKIQSCLAAGNTIVIKPAENTSLSLLYFAQLVKEAGFPPG 215
G VA I P+N+ + L GN + KP+ LS +L++EAG PPG
Sbjct: 199 GMEGFVAAIAPFNFTAIGGNLPTAPALM-GNVSLWKPSNTAVLSNYIIYELLEEAGMPPG 257
Query: 216 VLNILPGYGSVTGTAMASHTDIDKIAFTGSTAVGQKVMSLAAQSNLKAVTL-----ECGG 270
+L+ LP G V G + + + + FTGS + + A++ VT ECGG
Sbjct: 258 ILSFLPSDGPVFGDVITASPHLSAVNFTGSVPTFKTIWRKVAENLDNYVTFPKLIGECGG 317
Query: 271 KSPCLIFADANLDEAIPWVAGGIFYNSGQNCTANSRIYVHEDIYEEFLTKFEEYAKSNWK 330
K+ + A++D A + SGQ C+A SR+Y + I+ + L K K K
Sbjct: 318 KNFHFVHPSAHVDAVAAGTARSAWEYSGQKCSACSRMYAPKSIWPKILEKISAIHK-EIK 376
Query: 331 FGAKFDPFDKDCTLGPVISKVQYDRIQSYVEHGK-----ASEKLGFKEFAEYPSKGYFIP 385
G D D L VI + R+++Y++ K A+ LG K GYFI
Sbjct: 377 LG---DVRDGSVFLSAVIDDKAFARLKAYIDFAKTGADGANVVLGGK---CDDKTGYFIE 430
Query: 386 PTIFSDVPNSSKLSQEEIFGPVGVVASF--STYEEAIKLANDSS-YGLASCVFSENARTT 442
PT+ + SKL EE+FGPV V + S +E + D++ YGL VFS++
Sbjct: 431 PTLITVTDPKSKLLTEEMFGPVVTVLVYEDSKVDEVLATVKDATPYGLTGAVFSQDKEFL 490
Query: 443 AQFARDI---RAGTVWINSSNDEEI--SVPFGGFKMSGIGRELG 481
+ ARD+ G +++N + I PFGG ++SG + G
Sbjct: 491 YR-ARDVLRDAVGNMYLNDKSTGSIVGQQPFGGSRLSGTNDKAG 533
>YHR037w [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrogenase
Length = 575
Score = 135 bits (339), Expect = 2e-31
Identities = 127/490 (25%), Positives = 216/490 (43%), Gaps = 38/490 (7%)
Query: 22 LFINNEFVKSSDGKKI-ESINPSTEESIVSFFA-ASEKDVNSAVTAARDAFENNWSKTSG 79
L IN E + ++ + + NP+ + +++ A+EKDV +AV AA+DA + +W
Sbjct: 63 LVINGERIYDNNERALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDA-KKDWYNLPF 121
Query: 80 EQRGILLSKLFDLIE-RDKLLLAAIETLDSGKPYHSNSLADLEQILQLTRYYAGGADKFT 138
R + K DLI + + + A L GK + + + ++ RYY A
Sbjct: 122 YDRSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQAEIDCITELSDFFRYYVKYASDLY 181
Query: 139 GGEYIPLNQDKYAYTMKVPY-GVVAQIVPWNYPLAMASWKIQSCLAAGNTIVIKPAENTS 197
+ + + P G V + P+N+ A+A+ I + GNT+V KP++ +
Sbjct: 182 AQQPVESADGTWNKAEYRPLEGFVYAVSPFNFT-AIAANLIGAPALMGNTVVWKPSQTAA 240
Query: 198 LSLLYFAQLVKEAGFPPGVLNILPGYGSVTGTAMASHTDIDKIAFTGSTAVGQ----KVM 253
LS +++EAG P GV+N +PG + + D + FTGST V + K+
Sbjct: 241 LSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGALHFTGSTNVFKSLYGKIQ 300
Query: 254 SLAAQSNLK---AVTLECGGKSPCLIFADANLDEAIPWVAGGIFYNSGQNCTANSRIYVH 310
S + + + E GGK+ L+ AN+ A+ G F GQ C+A SR+Y+
Sbjct: 301 SGVVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQKCSAASRLYLP 360
Query: 311 EDIYEEFLTKFEEYAKSNWKFGAKFDPFDKDCT----------LGPVISKVQYDRIQSYV 360
E EEFL+ +S P + + +GPVI + +D++ +
Sbjct: 361 ESKSEEFLSDMFGILQSQ-----NVVPMNTSASPISGGNLRGFMGPVIHEQSFDKLVKVI 415
Query: 361 EHGKASEKLGFKEFAEY-PSKGYFIPPTIFSDVPNSSKLSQEEIFGPVGVVASF--STYE 417
E K +L +Y S+G+F+ PT+ E FGP+ V + + +
Sbjct: 416 EDAKKDPELEILYGGQYDKSQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYPDTEFN 475
Query: 418 EAIKLA-NDSSYGLASCVFSENARTTAQFARD---IRAGTVWINSSNDEEISVP--FGGF 471
E + N S Y L +F+++ R ++A + AG +IN + FGG
Sbjct: 476 EICDIIDNTSQYALTGAIFAKD-RKAIEYADEKLKFSAGNFYINDKCTGAVVSQQWFGGA 534
Query: 472 KMSGIGRELG 481
+MSG + G
Sbjct: 535 RMSGTDDKAG 544
>Hs4502045 [C] KOG2456 Aldehyde dehydrogenase
Length = 385
Score = 134 bits (338), Expect = 2e-31
Identities = 99/339 (29%), Positives = 161/339 (47%), Gaps = 17/339 (5%)
Query: 152 YTMKVPYGVVAQIVPWNYPLAMASWKIQSCLAAGNTIVIKPAENTSLSLLYFAQLVKEAG 211
+ K P+G+V I PWNYPL + + L AGN +V+KP+E + + A+++ +
Sbjct: 18 FIWKEPFGLVLIIAPWNYPLNLTLVLLVGTLPAGNCVVLKPSEISQGTEKVLAEVLPQY- 76
Query: 212 FPPGVLNILPGYGSVTGTAMASHTDIDKIAFTGSTAVGQKVMSLAAQSNLKAVTLECGGK 271
++ G TG + +D I FTGS VG+ VM+ AA +L VTLE GGK
Sbjct: 77 LDQSCFAVVLGGPQETGQLLEHK--LDYIFFTGSPRVGKIVMT-AATKHLTPVTLELGGK 133
Query: 272 SPCLIFADANLDEAIPWVAGGIFYNSGQNCTANSRIYVHEDIYEEFLTKFEEYAKSNWKF 331
+PC + + + VA ++N+GQ C A + ++ E L + +
Sbjct: 134 NPCYVDDNCDPQTVANRVAWFCYFNAGQTCVAPDYVLCSPEMQERLLPALQSTITRFYGD 193
Query: 332 GAKFDPFDKDCTLGPVISKVQYDRIQSYVEHGKASEKLGFKEFAEYPSKGYFIPPTIFSD 391
+ P LG +I++ Q+ R+++ + G+ + E Y I PT+ D
Sbjct: 194 DPQSSP-----NLGRIINQKQFQRLRALLGCGRVAIGGQSNESDRY------IAPTVLVD 242
Query: 392 VPNSSKLSQEEIFGPVGVVASFSTYEEAIKLANDSSYGLASCVFSENARTTAQFARDIRA 451
V + + QEEIFGP+ + + + +EAIK N LA FS + + Q +
Sbjct: 243 VQETEPVMQEEIFGPILPIVNVQSVDEAIKFINRQEKPLALYAFSNSRQVVNQMLERTSS 302
Query: 452 GTVWINS--SNDEEISVPFGGFKMSGIGRELGRNGVDSY 488
G+ N + +SVPFGG SG+GR G+ D++
Sbjct: 303 GSFGGNEGFTYISLLSVPFGGVGHSGMGRYHGKFTFDTF 341
>Hs4502043 [C] KOG2456 Aldehyde dehydrogenase
Length = 468
Score = 133 bits (335), Expect = 5e-31
Identities = 102/358 (28%), Positives = 169/358 (46%), Gaps = 20/358 (5%)
Query: 141 EYIPLN---QDKYAYTMKVPYGVVAQIVPWNYPLAMASWKIQSCLAAGNTIVIKPAENTS 197
E +P N Q A+ K P+G+V I PWNYPL + + LAAGN +V+KP+E +
Sbjct: 85 ERVPKNLATQLDSAFIRKEPFGLVLIIAPWNYPLNLTLVPLVGALAAGNCVVLKPSEISK 144
Query: 198 LSLLYFAQLVKEAGFPPGVLNILPGYGSVTGTAMASHTDIDKIAFTGSTAVGQKVMSLAA 257
A+++ + ++ G TG + D I FTGS VG+ VM+ AA
Sbjct: 145 NVEKILAEVLPQY-VDQSCFAVVLGGPQETGQLLEHR--FDYIFFTGSPRVGKIVMTAAA 201
Query: 258 QSNLKAVTLECGGKSPCLIFADANLDEAIPWVAGGIFYNSGQNCTANSRIYVHEDIYEEF 317
+ +L VTLE GGK+PC + + + VA ++N+GQ C A + ++ E
Sbjct: 202 K-HLTPVTLELGGKNPCYVDDNCDPQTVANRVAWFRYFNAGQTCVAPDYVLCSPEMQERL 260
Query: 318 LTKFEEYAKSNWKFGAKFDPFDKDCTLGPVISKVQYDRIQSYVEHGKASEKLGFKEFAEY 377
L + + + P LG +I++ Q+ R+++ + G+ + +G +
Sbjct: 261 LPALQSTITRFYGDDPQSSP-----NLGRIINQKQFQRLRALLGCGRVA--IG----GQS 309
Query: 378 PSKGYFIPPTIFSDVPNSSKLSQEEIFGPVGVVASFSTYEEAIKLANDSSYGLASCVFSE 437
+I PT+ DV + QEEIFGP+ + + + +EAI+ N LA FS
Sbjct: 310 DESDRYIAPTVLVDVQEMEPVMQEEIFGPILPIVNVQSLDEAIEFINRREKPLALYAFSN 369
Query: 438 NARTTAQFARDIRAGTVWINSS--NDEEISVPFGGFKMSGIGRELGRNGVDSYLQTKA 493
+++ + +G N + S+PFGG SG+GR G+ D++ +A
Sbjct: 370 SSQVVKRVLTQTSSGGFCGNDGFMHMTLASLPFGGVGASGMGRYHGKFSFDTFSHHRA 427
>7296504 [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrogenase
Length = 574
Score = 133 bits (334), Expect = 7e-31
Identities = 122/455 (26%), Positives = 199/455 (42%), Gaps = 26/455 (5%)
Query: 45 EESIVSFFAASEKDVNSAVTAARDAFENNWSKTSGEQRGILLSKLFDLIERD-KLLLAAI 103
+ + SF+ A +K + A+ A + + W + S R + K DL+ + L A
Sbjct: 97 QHKLASFYYADKKLIEKAIKTAVET-QPKWDRVSIADRLKIWEKAADLMATTYRQDLNAA 155
Query: 104 ETLDSGKPY---HSNSLADLEQILQLTRYYAGGADKFTG-GEYIPLNQDKYAYTMKVPYG 159
L K +S A+L +++ Y+ K+ E I + ++ Y + G
Sbjct: 156 TMLGQSKTAIQAEIDSAAELIDFIRMNAYFLKEVTKYQPISENIKVTKNSLRY--RGIDG 213
Query: 160 VVAQIVPWNYPLAMASWKIQSCLAAGNTIVIKPAENTSLSLLYFAQLVKEAGFPPGVLNI 219
+A + P+N+ + L GN ++ KP++ LS ++++EAG P GV+N
Sbjct: 214 FIAAVSPFNFTAIGGNLSYTPALM-GNGVLWKPSDTAMLSNWIIFKIMREAGVPDGVVNF 272
Query: 220 LPGYGSVTGTAMASHTDIDKIAFTGSTAVGQKVMSLAAQS-----NLKAVTLECGGKSPC 274
+P G V G + + + I FTGS ++ + N +T ECGGK+
Sbjct: 273 VPADGPVFGDTITASPHLAGINFTGSVPTFNRLWKQVGNNIDNYVNFPRLTGECGGKNFH 332
Query: 275 LIFADANLDEAIPWVAGGIFYNSGQNCTANSRIYVHEDIYEEFLTKFEEYAKSNWKFGAK 334
I A A+++ + F GQ C+A SR+YV E ++ + A + K G
Sbjct: 333 FIHASADVESVVTSTIRSAFEYCGQKCSACSRMYVPESLWPQIKEGLVCEA-AKLKIG-- 389
Query: 335 FDPFDKDCTLGPVISKVQYDRIQSYVEHGKASEKLGFKEFAEY-PSKGYFIPPTIFSDVP 393
D D VI + RI Y+EH K S L Y SKGYF+ PTI
Sbjct: 390 -DVQDFSSFTSAVIDDKAFKRITGYIEHAKKSPNLEILAGGTYSDSKGYFVNPTIVLSKD 448
Query: 394 NSSKLSQEEIFGPVGVVASF--STYEEAIKLANDSS-YGLASCVFSENARTTAQFARDIR 450
++ EEIFGPV + + S E +KL + S+ + L VF ++ ++ +
Sbjct: 449 PKDRIMTEEIFGPVLSIYVYKESDLLETMKLVHTSTKFALTGAVFGQDEDFVKCALQEFK 508
Query: 451 --AGTVWINSSNDEEI--SVPFGGFKMSGIGRELG 481
AG +IN + + PFGG +MSG + G
Sbjct: 509 MAAGNFYINDKSTGSVVGQQPFGGGRMSGTNDKAG 543
>7304212 [C] KOG2456 Aldehyde dehydrogenase
Length = 561
Score = 130 bits (328), Expect = 3e-30
Identities = 107/400 (26%), Positives = 179/400 (44%), Gaps = 25/400 (6%)
Query: 66 ARDAFENNWSKTSGEQRGILLSKLFDLIERDKLLLAAIETLDSGKPYHSNSLADLEQILQ 125
AR AF + ++ +R L + L E + +++A+E D +P + + + E +
Sbjct: 11 ARLAFSSGKTRNVSFRRKQLENLLRCYEEHENEIISALEA-DLRRPKQESLIVETEFMKN 69
Query: 126 LTRYYAGGADKFTGGEYIP---LNQDKYAYTMKVPYGVVAQIVPWNYPLAMASWKIQSCL 182
R+ D++ E P +N P+GVV I WNYPL + + S +
Sbjct: 70 DIRHILFQLDEWVQSEKPPKSFVNMMDDVQIYNDPFGVVLVIGAWNYPLQLLLVPVASAI 129
Query: 183 AAGNTIVIKPAENTSLSLLYFAQLVK---EAGFPPGVLNILPGYGSVTGTAMASHTDIDK 239
AAGN +VIKP+E + + A ++ + P V G + TA + D
Sbjct: 130 AAGNCVVIKPSEIAANCAKFIADVIPKYLDNDCYPVVC------GGPSETAELLNQRFDY 183
Query: 240 IAFTGSTAVGQKVMSLAAQSNLKAVTLECGGKSPCLIFADANLDEAIPWVAGGIFYNSGQ 299
I +TGST VG K++ AA L TLE GGKSPC I ++ A+ + G N GQ
Sbjct: 184 IFYTGSTRVG-KIIHAAANKYLTPTTLELGGKSPCYIDKSVDMRTAVKRILWGKLINCGQ 242
Query: 300 NCTANSRIYVHEDIYEEFLTKFEEYAKSNWKFGAKFDPFDKDCTLGPVISKVQYDRIQSY 359
C A I +++ E+F+ + ++ K + + P L VI+ + R+
Sbjct: 243 TCIAPDYILCSKEVQEKFIVEAKDVLKEWYGENIQSSP-----DLSRVINANNFQRLLGL 297
Query: 360 VEHGKASEKLGFKEFAEYPSKGYFIPPTIFSDVPNSSKLSQEEIFGPVGVVASFSTYEEA 419
++ G+ + Y + FI PTI DV + + +EEIFGP+ + + + +A
Sbjct: 298 MKSGRVAVG------GNYDASERFIEPTILVDVKETDPIMEEEIFGPILPIFNVESAYDA 351
Query: 420 IKLANDSSYGLASCVFSENARTTAQFARDIRAGTVWINSS 459
IK N L +F+ A F ++G + +N +
Sbjct: 352 IKFINARESPLVLYIFTPTAEVQNLFINGTQSGGLCVNDT 391
>Hs4502037 [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrogenase
Length = 563
Score = 127 bits (319), Expect = 4e-29
Identities = 112/448 (25%), Positives = 193/448 (43%), Gaps = 19/448 (4%)
Query: 48 IVSFFAASEKDVNSAVTAARDAFENNWSKTSGEQRGILLSKLFDLIERDKLLLAAIETL- 106
+ F A + +N A+ AA A W R + K D++ + +T+
Sbjct: 91 VAKFCYADKSLLNKAIEAALAA-RKEWDLKPIADRAQIFLKAADMLSGPRRAEILAKTMV 149
Query: 107 DSGKPYHSNSLADLEQILQLTRYYAGGADKFTGGEYIPLNQDKYAYTMKVPYGVVAQIVP 166
GK + +++ R+ A A + G + I + + + G VA I P
Sbjct: 150 GQGKTVIQAEIDAAAELIDFFRFNAKYAVELEGQQPISVPPSTNSTVYRGLEGFVAAISP 209
Query: 167 WNYPLAMASWKIQSCLAAGNTIVIKPAENTSLSLLYFAQLVKEAGFPPGVLNILPGYGSV 226
+N+ A+ + GN ++ KP++ L+ ++++EAG PP ++ +P G +
Sbjct: 210 FNFT-AIGGNLAGAPALMGNVVLWKPSDTAMLASYAVYRILREAGLPPNIIQFVPADGPL 268
Query: 227 TGTAMASHTDIDKIAFTGSTAVGQKVMSLAAQS-----NLKAVTLECGGKSPCLIFADAN 281
G + S + I FTGS + + AQ+ + ECGGK+ + A+
Sbjct: 269 FGDTVTSSEHLCGINFTGSVPTFKHLWKQVAQNLDRFHTFPRLAGECGGKNFHFVHRSAD 328
Query: 282 LDEAIPWVAGGIFYNSGQNCTANSRIYVHEDIYEEFLTKFEEYAKSNWKFGAKFDPFDKD 341
++ + F GQ C+A SR+YV ++ + + E S K G + F
Sbjct: 329 VESVVSGTLRSAFEYGGQKCSACSRLYVPHSLWPQIKGRLLE-EHSRIKVGDPAEDF--G 385
Query: 342 CTLGPVISKVQYDRIQSYVEHGKASEKLGFKEFAEY-PSKGYFIPPTIFSDVPNSSKLSQ 400
VI + RI+ ++EH ++S L + S GYF+ P I + +
Sbjct: 386 TFFSAVIDAKSFARIKKWLEHARSSPSLTILAGGKCDDSVGYFVEPCIVESKDPQEPIMK 445
Query: 401 EEIFGPVGVVASF--STYEEAIKLAND-SSYGLASCVFSENARTTAQFARDIR--AGTVW 455
EEIFGPV V + Y+E ++L + +SYGL VFS++ + + +R AG +
Sbjct: 446 EEIFGPVLSVYVYPDDKYKETLQLVDSTTSYGLTGAVFSQDKDVVQEATKVLRNAAGNFY 505
Query: 456 INSSNDEEI--SVPFGGFKMSGIGRELG 481
IN + I PFGG + SG + G
Sbjct: 506 INDKSTGSIVGQQPFGGARASGTNDKPG 533
>YMR110c [C] KOG2456 Aldehyde dehydrogenase
Length = 532
Score = 125 bits (315), Expect = 1e-28
Identities = 125/485 (25%), Positives = 209/485 (42%), Gaps = 43/485 (8%)
Query: 31 SSDGKKIESINPSTE-ESIV----SFFAASEKDVNSAVTAARDAFENNWSKTSGEQRGIL 85
S+DG KI + P ++ + IV +FF + ++ ENN K E R +
Sbjct: 2 SNDGSKILNYTPVSKIDEIVEISRNFFFEKQLKLSH---------ENNPRKKDLEFRQLQ 52
Query: 86 LSKLFDLI-ERDKLLLAAIETLDSGKPYHSNSLAD--------LEQILQLTRYYAGGADK 136
L KL+ + + ++ L+ A+ K +H N + + IL L
Sbjct: 53 LKKLYYAVKDHEEELIDAMY-----KDFHRNKIESVLNETTKLMNDILHLIEILPKLIKP 107
Query: 137 FTGGEYIPLNQDKYAYTMKVPYGVVAQIVPWNYPLAMASWKIQSCLAAGNTIVIKPAENT 196
+ P K+ G V I P+N+PL +A + + LAAGNTIV+KP+E T
Sbjct: 108 RRVSDSSPPFMFGKTIVEKISRGSVLIIAPFNFPLLLAFAPLAAALAAGNTIVLKPSELT 167
Query: 197 SLSLLYFAQLVKEAGFPPGVLNILPGYGSVTGTAMASHTDIDKIAFTGSTAVGQKVMSLA 256
+ + L+ AGFP G++ ++ G T T + D I +TGS VG V A
Sbjct: 168 PHTAVVMENLLTTAGFPDGLIQVVQGAIDET-TRLLDCGKFDLIFYTGSPRVGSIVAEKA 226
Query: 257 AQSNLKAVTLECGGKSPCLI---FADANLDEAIPWVAGGIFYNSGQNCTANSRIYVHEDI 313
A+S L LE GGKSP I F +N+ A+ + G F NSGQ C + + VH+ I
Sbjct: 227 AKS-LTPCVLELGGKSPTFITENFKASNIKIALKRIFFGAFGNSGQICVSPDYLLVHKSI 285
Query: 314 YEEFLTKFEEYAKSNWKFGAKFDPFDKDCTLGPVISKVQYDRIQSYVEHGKASEKLGFKE 373
Y + + + E + FD+ +I + Y + + + S+ + K
Sbjct: 286 YPKVIKECESV------LNEFYPSFDEQTDFTRMIHEPAYKKAVASINSTNGSKIVPSKI 339
Query: 374 FAEYPSKGY-FIPPTIFSDVPNSSKLSQEEIFGPVGVVASFSTYEEAI-KLANDSSYGLA 431
++ +PPTI ++ L ++E F PV + + +E I K+ + L
Sbjct: 340 SINSDTEDLCLVPPTIVYNIGWDDPLMKQENFAPVLPIIEYEDLDETINKIIEEHDTPLV 399
Query: 432 SCVFSENARTTAQFARDIRAGTVWINSS--NDEEISVPFGGFKMSGIGRELGRNGVDSYL 489
+FS++ + +R+G + + + PFGG SG G G G +++
Sbjct: 400 QYIFSDSQTEINRILTRLRSGDCVVGDTVIHVGITDAPFGGIGTSGYGNYGGYYGFNTFS 459
Query: 490 QTKAV 494
+ +
Sbjct: 460 HERTI 464
>Hs20546780 [C] KOG2450 Aldehyde dehydrogenase
Length = 637
Score = 122 bits (306), Expect = 1e-27
Identities = 101/346 (29%), Positives = 164/346 (47%), Gaps = 18/346 (5%)
Query: 159 GVVAQIVPWNYPLAMASWKIQSCLAAGNTIV--IKPAENTSLSLLYFAQLVKEAGFPPGV 216
GV+ I+P + W+I LA G T+V + PA L L AQL E G PG+
Sbjct: 2 GVIGLILPPTFSFLEMMWRICPALAVGCTVVALVPPASPAPLLL---AQLAGELGPFPGI 58
Query: 217 LNILPGYGSVTGTAMASHTDIDKIAFTGSTAVGQKVM-SLAAQSNLKAVTLECGGKSPCL 275
LN+L G S+ +AS I K+AF G+ G+ + SLA + + L G +S L
Sbjct: 59 LNVLSGPASLV-PILASQPGIRKVAFCGAPEEGRALRRSLAGEC--AELGLALGTESLLL 115
Query: 276 IFADANLDEAIPWVAGGIFYNSGQNCTANSRIYVHEDIYEEFLTKFEEYAKSNWKFGAKF 335
+ A++D A+ V + + G R+ + E +++E + + +E + G
Sbjct: 116 LTDTADVDSAVEGVVDAAWSDRGPG---GLRLLIQESVWDEAMRRLQE-RMGRLRSGRGL 171
Query: 336 DPFDKDCTLGPVISKVQYDRIQSYVEHGKASEKLGFKEFAEYPSKGYFIPPTIFSDVPNS 395
D G D +Q +V ++ F+ + PS+ F PPT+ S++P +
Sbjct: 172 DGAVDMGARGAAAC----DLVQRFVREAQSQGAQVFQA-GDVPSERPFYPPTLVSNLPPA 226
Query: 396 SKLSQEEIFGPVGVVASFSTYEEAIKLANDSSYGLASCVFSENARTTAQFARDIRAGTVW 455
S +Q E+ PV V + F T +EA+ +AN + G ++ V+SE + ++ GTVW
Sbjct: 227 SPCAQVEVPWPVVVASPFRTAKEALLVANGTPRGGSASVWSERLGQALELGYGLQVGTVW 286
Query: 456 INSSNDEEISVPFGGFKMSGIGRELGRNGVDSYLQTKAVHVNIAKL 501
IN+ + SVP GG K SG G +G+ YL+ ++ L
Sbjct: 287 INAHGLRDPSVPTGGCKESGCSWHGGPDGLYEYLRPSGTPARLSCL 332
Score = 65.9 bits (159), Expect = 1e-10
Identities = 69/256 (26%), Positives = 106/256 (40%), Gaps = 9/256 (3%)
Query: 10 PQLNITYEQPLGLFINNEFVKSSDGKKIESINPSTEESIVSFFAASEKDVNSAVTAARDA 69
P++ + P GLF+ F ++ + I S+ KD+ AV AA A
Sbjct: 353 PEIGPSPAPPYGLFVGGRF-QAPGARSSRPIRDSSGNLHGYVAEGGAKDIRGAVEAAHQA 411
Query: 70 FENNWSKTSGEQRGILLSKLFDLIERDKLLLAAIETLDSGKPYHSNSLADLEQILQLTRY 129
F W+ S R LL L +ER K LA+ + A+ E L R
Sbjct: 412 FPG-WAGQSPGARAALLWALAAALERRKSTLASRLERQGAEL----KAAEAEVELSARRL 466
Query: 130 YAGGADKFTGGEYIPLNQDKY-AYTMKVPYGVVAQIVPWNYPLAMASWKIQSCLAAGNTI 188
A GA G + + + ++ P GV+A + P +PL + LA GNT+
Sbjct: 467 RAWGARVQAQGHTLQVAGLRGPVLRLREPLGVLAVVCPDEWPLLAFVSLLAPALAYGNTV 526
Query: 189 VIKPAENTSLSLLYFAQLVKEAGFPPGVLNILPGYGSVTGTAMASHTDIDKIAFTGSTAV 248
V+ P+ L L Q + FP G+ N++ G +A H D+ + + GS A
Sbjct: 527 VMVPSAACPLLALEVCQDMATV-FPAGLANVVTGDRDHLTRCLALHQDVQAMWYFGS-AQ 584
Query: 249 GQKVMSLAAQSNLKAV 264
G + + A+ NLK V
Sbjct: 585 GSQFVEWASAGNLKPV 600
>SPBC24C6.04 [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrogenase
Length = 548
Score = 112 bits (280), Expect = 1e-24
Identities = 122/491 (24%), Positives = 203/491 (40%), Gaps = 64/491 (13%)
Query: 33 DGKKIESIN------PSTEESIVS-FFAASEKDVNSAVTAARDAFENNWSKTSGEQRGIL 85
DGK++E+ P + +V+ + A K V A+ AA + W R +
Sbjct: 50 DGKEVETNTIGEQRCPFEHKKVVARYHRAGAKHVEDAIEAALRG-KKVWESLPFADRSAI 108
Query: 86 LSKLFDLIE---RDKLLLAAIETLDSGKPYHSNSLADLEQILQLTRY--------YAGGA 134
K LI R KL+ A + + GK + +I+ R+ YA
Sbjct: 109 FLKAAHLISTKYRYKLMAATM--IGQGKNIWQAEIDAGMEIIDFLRFNTKYASELYASQP 166
Query: 135 DKFTGG-----EYIPLNQDKYAYTMKVPYGVVAQIVPWNYPLAMASWKIQSCLAAGNTIV 189
+ T G EY PL G V I P+N+ A+A + L GN ++
Sbjct: 167 PENTPGVWNRMEYRPLE------------GFVYAITPFNFT-AIAGNLAAAPLLMGNVVL 213
Query: 190 IKPAENTSLSLLYFAQLVKEAGFPPGVLNILPGYGSVTGTAMASHTDIDKIAFTGSTAVG 249
+KP+++ LS Q+ +EAG P G L +PG +H + + FTGSTAV
Sbjct: 214 MKPSDHAVLSSYIVYQIFREAGLPAGALQFIPGDAVEVSKVCFNHPEFAGLHFTGSTAVF 273
Query: 250 QKVMSLAAQS-------NLKAVTLECGGKSPCLIFADANLDEAIPWVAGGIFYNSGQNCT 302
+ + ++ + E GGK+ L+ + A + A+ F GQ C+
Sbjct: 274 RSLWGTIGENVANGKYRTYPKIVGETGGKNFHLVHSSAEIKSAVVNAVRAAFEYQGQKCS 333
Query: 303 ANSRIYVHEDIYEE-FLTKFEEYAKSNWKFGAKFDPFDKDCTLGPVISKVQYDRIQSYVE 361
A SR+YV + +E F + + KS K GA F +GPVI + +++++ +E
Sbjct: 334 ALSRLYVSKYAWENGFRDELTKQVKS-LKVGAPLTDFAN--FVGPVIHQASFNKLKKVLE 390
Query: 362 HGKASEKLGFKEFAEY-PSKGYFIPPTIFSDVPNSSKLSQEEIFGPVGVVASFSTYEE-- 418
+ ++ + S+G+F+ PT+ + E+FGP V S YE+
Sbjct: 391 SAASDSEIEVLAGGKADDSEGFFVEPTVLLSKNPKHDIFVNELFGP---VLSVYVYEDDN 447
Query: 419 ----AIKLANDSSYGLASCVFSENARTTAQFARDIR--AGTVWINSSNDEEI--SVPFGG 470
+ + YGL +F+++ + +R AG +IN + PFGG
Sbjct: 448 LDAVCDLIDTTTPYGLTGSIFAQDRVVVRKLTDRLRNAAGNFYINDKCTGAVVGEQPFGG 507
Query: 471 FKMSGIGRELG 481
+ SG + G
Sbjct: 508 ARASGTNDKAG 518
>At4g36250 [C] KOG2456 Aldehyde dehydrogenase
Length = 433
Score = 97.8 bits (242), Expect = 3e-20
Identities = 105/448 (23%), Positives = 189/448 (41%), Gaps = 68/448 (15%)
Query: 54 ASEKDVNSAVTAARDAFENNWSKTSGEQRGILLSKLFDLIE--RDKLLLAAIETLDSGKP 111
A ++ V ++ R+ F + ++ S + R + ++++++ DK+ A + D GK
Sbjct: 3 AMKETVEESLREMRETFASGRTR-SLKWRKAQIGAIYEMVKDNEDKICNALFQ--DLGKH 59
Query: 112 YHSNSLADLEQILQLTRYYAGGADKFTGGEYIPLNQDKYAYTMKV---PYGVVAQIVPWN 168
+L +L+ DK+ ++ L Y KV PYG V + WN
Sbjct: 60 STEAFRDELGVVLRTATVAINCLDKWAVPKHSKLPLLFYPAKGKVISEPYGTVLVLSSWN 119
Query: 169 YPLAMASWKIQSCLAAGNTIVIKPAENTSLSLLYFAQLVKEAGFPPGVLNILPGYGSVTG 228
+P++++ + +AAGNT+++K +E + + + A+ + A + ++ G G
Sbjct: 120 FPISLSLDPLIGAIAAGNTVLLKSSELSPNASAFLAKTI-PAYLDTKAIKVIEG-GPDVA 177
Query: 229 TAMASHTDIDKIAFTGSTAVGQKVMSLAAQSNLKAVTLECGGKSPCLIFADANLDEAIPW 288
T + H DKI FTGS +G+ +M+ AAQ +L VTLE GGKS
Sbjct: 178 TILLQH-QWDKIFFTGSPKIGRIIMAAAAQ-HLTPVTLELGGKS---------------- 219
Query: 289 VAGGIFYNSGQNCTANSRIYVHEDIYEEFLTKFEEYAKSNWKFGAKFDPFDKDCTLGPVI 348
C + + + + + + KS FG +P + C L +
Sbjct: 220 ------------CISVDYVLIEKSFAPTLIDMLKPTIKS--FFGE--NPKESGC-LSRIA 262
Query: 349 SKVQYDRIQSYVEHGKASEKLGFKEFAEYPSKGYFIPPTIFSDVPNSSKLSQEEIFGPVG 408
+K R+ + + PTI D P S++ EEIFGP+
Sbjct: 263 NKHHVQRLSRLLSDPR---------------------PTILLDPPLDSEIMNEEIFGPIL 301
Query: 409 VVASFSTYEEAIKLANDSSYGLASCVFSENARTTAQFARDIRAGTVWINSSNDEEI--SV 466
+ + +E+I + N LA F+ + + + +G+V N + + ++
Sbjct: 302 PIITVRDIQESIGIINTKPKPLAIYAFTNDENLKTRILSETSSGSVTFNDVMIQYMCDAL 361
Query: 467 PFGGFKMSGIGRELGRNGVDSYLQTKAV 494
PFGG SGIGR G+ D + KA+
Sbjct: 362 PFGGVGESGIGRYHGKYSFDCFSHEKAI 389
>7300788 [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrogenase
Length = 1590
Score = 94.7 bits (234), Expect = 3e-19
Identities = 81/335 (24%), Positives = 151/335 (44%), Gaps = 15/335 (4%)
Query: 159 GVVAQIVPWNYPLAMASWKIQSCLAAGNTIVIKPAENTSLSLLYFAQLVKEAGFPPGVLN 218
G VA I P+N+ A+ L GN+++ KP+++ LS + + ++EAG P GV+N
Sbjct: 235 GFVAAISPFNFTGIAANLAYTPALM-GNSVIWKPSDSAILSNYFVFKALREAGVPDGVVN 293
Query: 219 ILPGYGSVTGTAMASHTDIDKIAFTGSTAVGQKVMSLAAQS-----NLKAVTLECGGKSP 273
+P + + + H + I FTG++ V + + L AQ+ N + E GGK+
Sbjct: 294 FVPAEETTFASVVTQHPKLAGINFTGTSTVLKVLWQLVAQNINFYQNYPRLVGEGGGKNF 353
Query: 274 CLIFADANLDEAIPWVAGGIFYNSGQNCTANSRIYVHEDIYEEFLTKFEEYAKSNWKFGA 333
+ + A + A+ F +GQ C++ S +YV E +++ + E +
Sbjct: 354 HFVHSSAEPETAVACTIRAAFEYAGQKCSSCSMLYVPESLWQNHIR--EPLLEITASLVV 411
Query: 334 KFDPFDKDCTLGPVISKVQYDRIQSYVEHGKASEKLGFKEFAEYPS-KGYFIPPTIFSDV 392
+ D D VI++ YDRI ++ + S +GY++ PT+
Sbjct: 412 RQDATYCDSFCSAVINRRAYDRIYMWLRYIDQSPSCQILVGGSCDKRRGYYVDPTVVLVK 471
Query: 393 PNSSKLSQEEIFGPVGVVASFSTY--EEAIKLANDSSYGLASCVFS--ENARTTAQFARD 448
+ + +EE+ P+ V + + +E ++ ++GL VF+ +N A A
Sbjct: 472 DLDNIICREELLAPILGVYVYPDHKLKETMEKVAQINHGLTGSVFAQDQNFIEEAYDAFR 531
Query: 449 IRAGTVWINSSNDEEI--SVPFGGFKMSGIGRELG 481
+ G + +N + + PFG M+G +LG
Sbjct: 532 VNVGNLNVNDKSTGLMVGQQPFGAGHMTGTSDKLG 566
>Hs20481620 [C] KOG2456 Aldehyde dehydrogenase
Length = 292
Score = 90.1 bits (222), Expect = 7e-18
Identities = 63/213 (29%), Positives = 104/213 (48%), Gaps = 9/213 (4%)
Query: 151 AYTMKVPYGVVAQIVPWNYPLAMASWKIQSCLAAGNTIVIKPAENTSLSLLYFAQLVKEA 210
A+ K P+G+V I PWNYPL + + LAAGN +V+KP+E + A+++ +
Sbjct: 61 AFIRKEPFGLVLIIAPWNYPLNLTLVPLVGALAAGNCVVLKPSEISKNVEKILAEVLPQY 120
Query: 211 GFPPGVLNILPGYGSVTGTAMASHTDIDKIAFTGSTAVGQKVMSLAAQSNLKAVTLECGG 270
++ G TG + D I FTGS VG+ VM+ AA+ +L VTLE GG
Sbjct: 121 -VDQSCFAVVLGGPQETGQLLEHR--FDYIFFTGSPRVGKIVMTAAAK-HLTPVTLELGG 176
Query: 271 KSPCLIFADANLDEAIPWVAGGIFYNSGQNCTANSRIYVHEDIYEEFLTKFEEYAKSNWK 330
K+PC + + + VA ++N+GQ C A + ++ E L + +
Sbjct: 177 KNPCYVDDNCDPQTVANRVAWFRYFNAGQTCVAPDYVLCSPEMQERLLPALQSTITRFYG 236
Query: 331 FGAKFDPFDKDCTLGPVISKVQYDRIQSYVEHG 363
+ P LG +I++ Q+ R+++ + G
Sbjct: 237 DDPQSSP-----NLGRIINQKQFQRLRALLGCG 264
>At4g34240 [C] KOG2456 Aldehyde dehydrogenase
Length = 533
Score = 82.8 bits (203), Expect = 1e-15
Identities = 82/318 (25%), Positives = 140/318 (43%), Gaps = 32/318 (10%)
Query: 182 LAAGNTIVIKPAENTSLSLLYFAQLVKEAGFPPGVLNILPGYGSVTGTAMASHTDIDKIA 241
+AAGN +V+KP+E + A+L E + ++ G V T DKI
Sbjct: 197 IAAGNAVVLKPSEIAPAASSLLAKLFSEY-LDNTTIRVIEG--GVPETTALLDQKWDKIF 253
Query: 242 FTG-STAVGQKVMSLAAQSNLKAVTLECGGKSPCLIFADANLDEAIPWVAGGIFYNSGQN 300
FT S + K++ + + + + L+ + +AG NSGQ
Sbjct: 254 FTDLSLLLKHKIVKFRSHTLIVVLWLKVAARRI---------------IAGKWACNSGQA 298
Query: 301 CTANSRIYVHEDIYEEFLTKFEEYAKSNWK-FGAKFDPFDKDCTLGPVISKVQYDRIQSY 359
C + +D F +K + K+ + F + KD L +++ + R++S
Sbjct: 299 CIGVDYVITTKD----FASKLIDALKTELETFFGQNALESKD--LSRIVNSFHFKRLESM 352
Query: 360 V-EHGKASEKLGFKEFAEYPSKGYFIPPTIFSDVPNSSKLSQEEIFGPVGVVASFSTYEE 418
+ E+G A++ + E K I PTI DVP +S + QEEIFGP+ + + E+
Sbjct: 353 LKENGVANKIVHGGRITEDKLK---ISPTILLDVPEASSMMQEEIFGPLLPIITVQKIED 409
Query: 419 AIKLANDSSYGLASCVFSENARTTAQFARDIRAGTVWINSS--NDEEISVPFGGFKMSGI 476
++ LA+ +F+ N QF +D+ AG + IN + + +PFGG SGI
Sbjct: 410 GFQVIRSKPKPLAAYLFTNNKELEKQFVQDVSAGGITINDTVLHVTVKDLPFGGVGESGI 469
Query: 477 GRELGRNGVDSYLQTKAV 494
G G+ +++ K V
Sbjct: 470 GAYHGKFSYETFSHKKGV 487
>7294423 [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrogenase
Length = 560
Score = 82.4 bits (202), Expect = 1e-15
Identities = 105/457 (22%), Positives = 192/457 (41%), Gaps = 35/457 (7%)
Query: 45 EESIVSFFAASEKDVNSAVTAARDAFENNWSKTSGEQRGILLSKLFDLIERDKLLLAAIE 104
+ ++ + A+ K + +A+ +A A + WS QR + + +IE D+L L
Sbjct: 88 QTNLAHVYYANRKQIEAAIKSALSA-QGTWSLVPIAQRLAIWRRAATIIEEDELRLRVFL 146
Query: 105 TLDSGKPYHSNSLADLEQILQLTRYYAGGADKFTGGEY-IPLNQDKY-AYTMKVPYGVVA 162
+ K ++ D+ ++L R A + + + I + + + ++ ++ G VA
Sbjct: 147 MMTLSKTA-DDATRDIRRLLTSLRANADYLEHLSELRFEIQGDMNVFPSFHLRPMDGFVA 205
Query: 163 QIVPWNYPLAMASWKIQSCLAAGNTIVIKPA-ENTSLSLLYFAQLVKEAGFPPGVLNILP 221
+ P+ +S + L GNT++ P+ E +S L F + +EAG P GV+N +P
Sbjct: 206 ALAPFESVALSSSLALCPALM-GNTVLWNPSLEVAPVSYLIF-RAFQEAGLPSGVINFVP 263
Query: 222 GYGSVTGTAMASHTDIDKIAFTG-----STAVGQKVMSLAAQSNLKAV-----TLECGGK 271
+ T D + F G S A + V L + + + EC G+
Sbjct: 264 -----ANERLFLDTITDAVHFAGLNTQASAAFYRHVHKLVSDRMERYICFPRLVAECPGQ 318
Query: 272 SPCLIFADANLDEAIPWVAGGIFYNSGQNCTANSRIYVHEDIYEEFLTKFEEYAKSNWKF 331
+ + A A ++ + F +GQ + SR+YV ++ + E A
Sbjct: 319 NFHFVHASAKVESVVSATVQAAFGFAGQYANSLSRMYVPSSMWPRLREELVE-ATEQLTI 377
Query: 332 GAKFDPFDKDCTLGPVISKVQYDRIQSYVEHGKASEKLGFKEFAEYPSKGYFIPPTIFSD 391
G DP + + +G ++ + R+Q ++ K E+L + S G F+ PTI
Sbjct: 378 G---DPIESETDIGAMVHINDFRRMQKLLQRTKNMEQLCGGSCDD--STGRFVDPTIVRV 432
Query: 392 VPNSSKLSQEEIFGPVGVVASFS--TYEEAIKL-ANDSSYGLASCVFSENARTTAQFARD 448
L E GP V +S ++ EA+KL AN S Y L+ +F+
Sbjct: 433 SDPLDPLLCEPCCGPFLPVFVYSDDSFSEALKLAANQSRYALSGSIFASQDEVILHCLNQ 492
Query: 449 IR--AGTVWINS--SNDEEISVPFGGFKMSGIGRELG 481
+R A +++N + PFGG ++SG + G
Sbjct: 493 LRMSASNLYVNERCTGSTYGLTPFGGNRLSGTNDKSG 529
>Hs20479244 [C] KOG2450 Aldehyde dehydrogenase
Length = 292
Score = 78.6 bits (192), Expect = 2e-14
Identities = 47/148 (31%), Positives = 78/148 (51%), Gaps = 1/148 (0%)
Query: 354 DRIQSYVEHGKASEKLGFKEFAEYPSKGYFIPPTIFSDVPNSSKLSQEEIFGPVGVVASF 413
D +Q +V ++ F+ + PS+ F PPT+ S++P +S +Q E+ PV V + F
Sbjct: 32 DLVQRFVREAQSQGAQVFQA-GDVPSERPFYPPTLVSNLPPASPCAQVEVPWPVVVASPF 90
Query: 414 STYEEAIKLANDSSYGLASCVFSENARTTAQFARDIRAGTVWINSSNDEEISVPFGGFKM 473
T +EA+ +AN + G ++ V+SE + ++ GTVWIN+ + SVP GG K
Sbjct: 91 RTAKEALLVANGTPRGGSASVWSERLGQALELGYGLQVGTVWINAHGLRDPSVPTGGCKE 150
Query: 474 SGIGRELGRNGVDSYLQTKAVHVNIAKL 501
SG G +G+ YL+ ++ L
Sbjct: 151 SGCSWHGGPDGLYEYLRPSGTPARLSCL 178
>At5g62530 [C] KOG2451 Aldehyde dehydrogenase
Length = 563
Score = 62.0 bits (149), Expect = 2e-09
Identities = 66/283 (23%), Positives = 124/283 (43%), Gaps = 30/283 (10%)
Query: 145 LNQDKYAYTMKVPYGVVAQIVPWNYPLAMASWKIQSCLAAGNTIVIKPAENTSLSLLYFA 204
L Q + Y + PYG V + P+N+PL + ++ L GN ++K S+ +
Sbjct: 193 LGQQSHGY--RWPYGPVTIVTPFNFPLEIPLLQLMGALYMGNKPLLKVDSKVSIVMEQMM 250
Query: 205 QLVKEAGFPPGVLNILPGYGSVTGTAMASHTDIDKIAFTGSTAVGQKVMSLAAQSNLKAV 264
+L+ G P ++ + G T + + FTGS+ V +K ++L + ++
Sbjct: 251 RLLHYCGLPAEDVDFINSDGK-TMNKILLEANPRMTLFTGSSRVAEK-LALDLKGRIR-- 306
Query: 265 TLECGGKSPCLIFADANLDEAIPWVAGGIFYN-SGQNCTANSRIYVHEDIYE-EFLTKFE 322
LE G ++ D + + W Y SGQ C+A S ++VHE+ + ++K +
Sbjct: 307 -LEDAGFDWKVLGPDVQEVDYVAWQCDQDAYACSGQKCSAQSMLFVHENWSKTPLVSKLK 365
Query: 323 EYAKSNWKFGAKFDPFDKDCTLGPVI---SKVQYDRIQSYVEHGKASEKLGFKEFAEY-- 377
E A+ +D T+GPV+ ++ + +++ ++ + G KE +
Sbjct: 366 ELAERRKL---------EDLTIGPVLTFTTEAMLEHMENLLQIPGSKLLFGGKELKNHSI 416
Query: 378 PS-KGYFIPPTIFSDVPNSSK------LSQEEIFGPVGVVASF 413
PS G P ++ + K L +EIFGP +V +
Sbjct: 417 PSIYGALEPTAVYVPIEEILKDNKTYELVTKEIFGPFQIVTEY 459
>Hs21614515 [F] KOG2452 Formyltetrahydrofolate dehydrogenase
Length = 505
Score = 55.5 bits (132), Expect = 2e-07
Identities = 32/73 (43%), Positives = 38/73 (51%), Gaps = 1/73 (1%)
Query: 15 TYEQPLGLFINNEFVKSSDGKKIESINPSTEESIVSFFAASEKDVNSAVTAARDAFEN-N 73
T P LFI EFV + K E+INP+ I A DV+ AV AA+DAFEN
Sbjct: 417 TVRMPHQLFIGGEFVDAEGAKTSETINPTDGSVICQVSLAQVTDVDKAVAAAKDAFENGR 476
Query: 74 WSKTSGEQRGILL 86
W K S RG L+
Sbjct: 477 WGKISARDRGRLM 489
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.315 0.133 0.386
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 30,262,914
Number of Sequences: 60738
Number of extensions: 1306563
Number of successful extensions: 3512
Number of sequences better than 1.0e-05: 77
Number of HSP's better than 0.0 without gapping: 58
Number of HSP's successfully gapped in prelim test: 19
Number of HSP's that attempted gapping in prelim test: 3138
Number of HSP's gapped (non-prelim): 83
length of query: 501
length of database: 30,389,216
effective HSP length: 111
effective length of query: 390
effective length of database: 23,647,298
effective search space: 9222446220
effective search space used: 9222446220
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)