ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIV2485 good C KOG2450 Energy production and conversion Aldehyde dehydrogenase
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIV2485 847239 848747 503
(503 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
SPAC922.07c [C] KOG2450 Aldehyde dehydrogenase 486 e-137
YMR170c [C] KOG2450 Aldehyde dehydrogenase 439 e-123
YMR169c [C] KOG2450 Aldehyde dehydrogenase 438 e-123
Hs10835045 [C] KOG2450 Aldehyde dehydrogenase 428 e-120
7297513 [C] KOG2450 Aldehyde dehydrogenase 422 e-118
SPAC9E9.09c [C] KOG2450 Aldehyde dehydrogenase 414 e-115
Hs11436533 [C] KOG2450 Aldehyde dehydrogenase 409 e-114
Hs19923115 [C] KOG2450 Aldehyde dehydrogenase 409 e-114
Hs4502041 [C] KOG2450 Aldehyde dehydrogenase 404 e-112
HsM4502031 [C] KOG2450 Aldehyde dehydrogenase 403 e-112
Hs21361176 [C] KOG2450 Aldehyde dehydrogenase 403 e-112
YOR374w [C] KOG2450 Aldehyde dehydrogenase 399 e-111
Hs4502033 [C] KOG2450 Aldehyde dehydrogenase 399 e-111
CE23852 [C] KOG2450 Aldehyde dehydrogenase 395 e-110
YER073w [C] KOG2450 Aldehyde dehydrogenase 387 e-107
7301524 [C] KOG2450 Aldehyde dehydrogenase 385 e-107
At1g23800 [C] KOG2450 Aldehyde dehydrogenase 379 e-105
CE29393 [C] KOG2450 Aldehyde dehydrogenase 377 e-104
YPL061w [C] KOG2450 Aldehyde dehydrogenase 375 e-104
At3g48000 [C] KOG2450 Aldehyde dehydrogenase 368 e-101
Hs18579349 [F] KOG2452 Formyltetrahydrofolate dehydrogenase 348 1e-95
Hs21614513 [F] KOG2452 Formyltetrahydrofolate dehydrogenase 343 3e-94
HsM7110595 [F] KOG2452 Formyltetrahydrofolate dehydrogenase 337 2e-92
At3g48170 [C] KOG2450 Aldehyde dehydrogenase 325 1e-88
At1g74920 [C] KOG2450 Aldehyde dehydrogenase 308 2e-83
Hs4502047 [C] KOG2450 Aldehyde dehydrogenase 303 3e-82
Hs12007648 [C] KOG2450 Aldehyde dehydrogenase 299 7e-81
CE07233 [C] KOG2450 Aldehyde dehydrogenase 298 1e-80
SPCC550.10 [C] KOG2450 Aldehyde dehydrogenase 287 2e-77
CE05817 [F] KOG2452 Formyltetrahydrofolate dehydrogenase 283 6e-76
CE24573 [C] KOG2450 Aldehyde dehydrogenase 278 2e-74
SPAC139.05 [C] KOG2451 Aldehyde dehydrogenase 268 1e-71
CE06980 [C] KOG2450 Aldehyde dehydrogenase 268 1e-71
7298784 [F] KOG2452 Formyltetrahydrofolate dehydrogenase 260 3e-69
At1g79440 [C] KOG2451 Aldehyde dehydrogenase 258 2e-68
YBR006w [C] KOG2451 Aldehyde dehydrogenase 253 4e-67
SPAC1002.12c [C] KOG2451 Aldehyde dehydrogenase 248 2e-65
7301355 [C] KOG2451 Aldehyde dehydrogenase 239 7e-63
Hs4507229 [C] KOG2451 Aldehyde dehydrogenase 236 5e-62
CE10542 [C] KOG2451 Aldehyde dehydrogenase 225 1e-58
CE02183 [EG] KOG2449 Methylmalonate semialdehyde dehydrogenase 211 2e-54
At2g14170 [EG] KOG2449 Methylmalonate semialdehyde dehydrogenase 206 5e-53
SPBC21C3.15c [C] KOG2454 Betaine aldehyde dehydrogenase 205 1e-52
At1g54100 [C] KOG2453 Aldehyde dehydrogenase 204 3e-52
Hs11095441 [EG] KOG2449 Methylmalonate semialdehyde dehydrogenase 202 7e-52
7290043 [EG] KOG2449 Methylmalonate semialdehyde dehydrogenase 201 2e-51
At3g66658 [C] KOG2454 Betaine aldehyde dehydrogenase 201 3e-51
CE01232 [C] KOG2453 Aldehyde dehydrogenase 200 4e-51
Hs4557343 [C] KOG2453 Aldehyde dehydrogenase 191 2e-48
7293810 [C] KOG2453 Aldehyde dehydrogenase 182 1e-45
YHR039c [C] KOG1772 Vacuolar H+-ATPase V1 sector subunit G 165 2e-40
At2g24270 [C] KOG2450 Aldehyde dehydrogenase 164 4e-40
HsM4502035 [C] KOG2456 Aldehyde dehydrogenase 152 1e-36
Hs21359829 [C] KOG2456 Aldehyde dehydrogenase 152 1e-36
Hs4557303 [C] KOG2456 Aldehyde dehydrogenase 147 4e-35
Hs18603595 [C] KOG2456 Aldehyde dehydrogenase 147 4e-35
CE13415 [C] KOG2456 Aldehyde dehydrogenase 142 1e-33
Hs4502037 [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrogenase 136 6e-32
CE27441 [C] KOG2456 Aldehyde dehydrogenase 136 8e-32
7296504 [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrogenase 135 2e-31
CE29047 [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrogenase 129 1e-29
YHR037w [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrogenase 127 4e-29
SPBC24C6.04 [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrog... 122 1e-27
At1g44170 [C] KOG2456 Aldehyde dehydrogenase 120 4e-27
Hs4502043 [C] KOG2456 Aldehyde dehydrogenase 119 8e-27
YMR110c [C] KOG2456 Aldehyde dehydrogenase 118 2e-26
Hs4502045 [C] KOG2456 Aldehyde dehydrogenase 114 3e-25
Hs20546780 [C] KOG2450 Aldehyde dehydrogenase 109 8e-24
7304212 [C] KOG2456 Aldehyde dehydrogenase 105 2e-22
7300788 [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrogenase 105 2e-22
At4g36250 [C] KOG2456 Aldehyde dehydrogenase 98 3e-20
7294423 [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrogenase 81 4e-15
Hs20481620 [C] KOG2456 Aldehyde dehydrogenase 79 2e-14
At4g34240 [C] KOG2456 Aldehyde dehydrogenase 64 4e-10
Hs20479244 [C] KOG2450 Aldehyde dehydrogenase 57 8e-08
At5g62530 [C] KOG2451 Aldehyde dehydrogenase 53 9e-07
Hs21614515 [F] KOG2452 Formyltetrahydrofolate dehydrogenase 52 3e-06
>SPAC922.07c [C] KOG2450 Aldehyde dehydrogenase
Length = 496
Score = 486 bits (1251), Expect = e-137
Identities = 247/502 (49%), Positives = 335/502 (66%), Gaps = 12/502 (2%)
Query: 3 FTSIKLADGTEYQQPLGLFINNEYVEAHGSETLTSYNPSSGEEICKVQCADPKIDVDLAV 62
F SI +G +QP+GL+IN E+ ++ +ET + +PS E I KV A K ++D AV
Sbjct: 6 FVSINFPNGKSVKQPIGLYINGEWHKS--AETWETVDPSIEEVIAKVYLAGEK-EIDYAV 62
Query: 63 KAARDAFPGWKATPAIEKRDLFYKLAGLLERDIDILSKIESLDTGKPIANNAKYDILEVV 122
K+A++AF WK P EK +L KLA L E+ D L+ IE++D+GKP+ +NA+ D+ +
Sbjct: 63 KSAKEAFKTWKKVPGSEKGELLMKLAELTEKHADTLAAIEAMDSGKPLVSNARGDVDGTI 122
Query: 123 EVLKYYAGWIDKAGGQSFAPSSEKLAYTLHQPLGVVGCIIPFNYPLAMMSWKWT-AIATG 181
+L+Y AGW DK GQ EKLAY P+GV G I+P+NYPL M WK A+A G
Sbjct: 123 ALLRYCAGWADKIYGQVIPTGPEKLAYAKRTPIGVCGQIVPWNYPLNMAGWKIAPALAAG 182
Query: 182 NTTVFKSADQTPLSILYFAKLVKEAGFPAGVFNVLSGTGASVGSAIVKHTGVDKIAFTGS 241
N + KSA+ TPLS+LYFA LV+EAGFP GV N++SG G GS + KH G+DKIAFTGS
Sbjct: 183 NCIIIKSAETTPLSLLYFATLVEEAGFPKGVVNIISGLGTVAGSYMAKHPGIDKIAFTGS 242
Query: 242 TAVGQIIQQQSAVNLKPITLECGGKSANMIFEDCDLEQAVKWSAWGIFNNMGQICSGTSR 301
T VG I+QQ +A NLK +TLECGGKS ++FED DL+QAVKW+A GI N GQIC+ SR
Sbjct: 243 TKVGVIVQQLAASNLKAVTLECGGKSPFLVFEDADLDQAVKWAALGIMYNSGQICTSNSR 302
Query: 302 VFVQESIYEEFVAQLADHVKKTYIVGAPSDDAVIVGPQVSKKQQERVLEYIKIGIEEGCK 361
++VQ+S+Y++F+ HV + YIVG P DD +VGP V+K Q R+ YI+ G +EG K
Sbjct: 303 IYVQDSVYDKFIELFKKHVIQDYIVGMPFDDNTVVGPVVNKTQYNRIKNYIEQGKKEGAK 362
Query: 362 VPLGGLGAPEPIANDPALANGYYVKPTILADVKASYRIAKEEIFGPVIVVGSFKDYKEAL 421
+ LG EP+ L GY++ PTI AD + I KEEIFGPV+ + FK EA+
Sbjct: 363 LVLG----DEPL----PLKQGYFISPTIFADCSENMTIVKEEIFGPVVAISKFKTEDEAI 414
Query: 422 DIANDSDYGLGSAIFSKDIVTCHKFAQDVEAGMVWINSSNDVDINVPFGGVKMSGHGREL 481
+ AN++ YGL + F+KD+ H+ + ++EAGMV+INS+ + DI PFGG+KMSG G EL
Sbjct: 415 EKANNTTYGLAAMCFTKDLERAHRVSDELEAGMVFINSTENSDIQAPFGGIKMSGIGNEL 474
Query: 482 GEYGLANFTNVKSVHVNLGRKL 503
G G+ +T +K+VH+N KL
Sbjct: 475 GSNGIEMYTQIKAVHINFNNKL 496
>YMR170c [C] KOG2450 Aldehyde dehydrogenase
Length = 506
Score = 439 bits (1130), Expect = e-123
Identities = 233/499 (46%), Positives = 321/499 (63%), Gaps = 28/499 (5%)
Query: 15 QQPLGLFINNEYVEAHGSETLTSYNPSSGEEICKVQCADPKIDVDLAVKAARDAFPG-WK 73
+QPLGLFINNE+ + +T+ + NP++GE I Q A+ K DVD AVKAAR AF W
Sbjct: 18 KQPLGLFINNEFCPSSDGKTIETVNPATGEPITSFQAANEK-DVDKAVKAARAAFDNVWS 76
Query: 74 ATPAIEKRDLFYKLAGLLERDIDILSKIESLDTGKPIANNAKYDILEVVEVLKYYAGWID 133
T + ++ L L+E + D L+ +E+LD GKP +NAK D+ +++++ +Y+AG D
Sbjct: 77 KTSSEQRGIYLSNLLKLIEEEQDTLAALETLDAGKPYHSNAKGDLAQILQLTRYFAGSAD 136
Query: 134 KAG-GQSFAPSSEKLAYTLHQPLGVVGCIIPFNYPLAMMSWKWT-AIATGNTTVFKSADQ 191
K G + + K AYTL P GVV I+P+NYPLAM WK A+A GNT + K A+
Sbjct: 137 KFDKGATIPLTFNKFAYTLKVPFGVVAQIVPWNYPLAMACWKLQGALAAGNTVIIKPAEN 196
Query: 192 TPLSILYFAKLVKEAGFPAGVFNVLSGTGASVGSAIVKHTGVDKIAFTGSTAVGQIIQQQ 251
T LS+LYFA L+K+AGFP GV N++ G G+ VG A+ H +DKI+FTGST VG + +
Sbjct: 197 TSLSLLYFATLIKKAGFPPGVVNIVPGYGSLVGQALASHMDIDKISFTGSTKVGGFVLEA 256
Query: 252 SAV-NLKPITLECGGKSANMIFEDCDLEQAVKWSAWGIFNNMGQICSGTSRVFVQESIYE 310
S NLK +TLECGGKS ++FED DL++A+ W A GIF N GQ C+ SRV+VQ SIY+
Sbjct: 257 SGQSNLKDVTLECGGKSPALVFEDADLDKAIDWIAAGIFYNSGQNCTANSRVYVQSSIYD 316
Query: 311 EFVAQLADHVKKTYIVGA---PSDDAVIVGPQVSKKQQERVLEYIKIGIEEG-------C 360
+FV + + KK + V P D+ IVGP +S Q +R+ YI+ G E
Sbjct: 317 KFVEKFKETAKKEWDVAGKFDPFDEKCIVGPVISSTQYDRIKSYIERGKREEKLDMFQTS 376
Query: 361 KVPLGGLGAPEPIANDPALANGYYVKPTILADVKASYRIAKEEIFGPVIVVGSFKDYKEA 420
+ P+GG A GY++ PTI DV + ++ ++EIFGPV+VV F +Y +A
Sbjct: 377 EFPIGG-------------AKGYFIPPTIFTDVPQTSKLLQDEIFGPVVVVSKFTNYDDA 423
Query: 421 LDIANDSDYGLGSAIFSKDIVTCHKFAQDVEAGMVWINSSNDVDINVPFGGVKMSGHGRE 480
L +AND+ YGL SA+F+KD+ H FA+D++AG VWINSSND D+ VPFGG KMSG GRE
Sbjct: 424 LKLANDTCYGLASAVFTKDVKKAHMFARDIKAGTVWINSSNDEDVTVPFGGFKMSGIGRE 483
Query: 481 LGEYGLANFTNVKSVHVNL 499
LG+ G+ + K+VH+NL
Sbjct: 484 LGQSGVDTYLQTKAVHINL 502
>YMR169c [C] KOG2450 Aldehyde dehydrogenase
Length = 506
Score = 438 bits (1127), Expect = e-123
Identities = 233/499 (46%), Positives = 323/499 (64%), Gaps = 28/499 (5%)
Query: 15 QQPLGLFINNEYVEAHGSETLTSYNPSSGEEICKVQCADPKIDVDLAVKAARDAFPG-WK 73
+QPLGLFINNE+ + +T+ + NP++GE I Q A+ K DVD AVKAAR AF W
Sbjct: 18 KQPLGLFINNEFCPSSDGKTIETVNPATGEPITSFQAANEK-DVDKAVKAARAAFDNVWS 76
Query: 74 ATPAIEKRDLFYKLAGLLERDIDILSKIESLDTGKPIANNAKYDILEVVEVLKYYAGWID 133
T + ++ L L+E + D L+ +E+LD GKP +NAK D+ +++E+ +YYAG +D
Sbjct: 77 KTSSEQRGIYLSNLLKLIEEEQDTLAALETLDAGKPFHSNAKQDLAQIIELTRYYAGAVD 136
Query: 134 KAG-GQSFAPSSEKLAYTLHQPLGVVGCIIPFNYPLAMMSWKWT-AIATGNTTVFKSADQ 191
K G++ + K AYTL P GVV I+P+NYPLAM K A+A GNT + K A+
Sbjct: 137 KFNMGETIPLTFNKFAYTLKVPFGVVAQIVPWNYPLAMACRKMQGALAAGNTVIIKPAEN 196
Query: 192 TPLSILYFAKLVKEAGFPAGVFNVLSGTGASVGSAIVKHTGVDKIAFTGSTAVG-QIIQQ 250
T LS+LYFA L+K+AGFP GV NV+ G G+ VG A+ H +DKI+FTGST VG +++
Sbjct: 197 TSLSLLYFATLIKKAGFPPGVVNVIPGYGSVVGKALGTHMDIDKISFTGSTKVGGSVLEA 256
Query: 251 QSAVNLKPITLECGGKSANMIFEDCDLEQAVKWSAWGIFNNMGQICSGTSRVFVQESIYE 310
NLK ITLECGGKS ++FED DL++A++W A GIF N GQIC+ SRV+VQ SIY+
Sbjct: 257 SGQSNLKDITLECGGKSPALVFEDADLDKAIEWVANGIFFNSGQICTANSRVYVQSSIYD 316
Query: 311 EFVAQLADHVKKTYIVGA---PSDDAVIVGPQVSKKQQERVLEYIKIGIEEG-------C 360
+FV + + KK + V P D+ IVGP +S Q +R+ YI+ G +E
Sbjct: 317 KFVEKFKETAKKEWDVAGKFDPFDEKCIVGPVISSTQYDRIKSYIERGKKEEKLDMFQTS 376
Query: 361 KVPLGGLGAPEPIANDPALANGYYVKPTILADVKASYRIAKEEIFGPVIVVGSFKDYKEA 420
+ P+GG A GY++ PTI DV + ++ ++EIFGPV+VV F +Y +A
Sbjct: 377 EFPIGG-------------AKGYFIPPTIFTDVPETSKLLRDEIFGPVVVVSKFTNYDDA 423
Query: 421 LDIANDSDYGLGSAIFSKDIVTCHKFAQDVEAGMVWINSSNDVDINVPFGGVKMSGHGRE 480
L +AND+ YGL SA+F+KD+ H FA+D++AG VWIN +N + VPFGG KMSG GRE
Sbjct: 424 LKLANDTCYGLASAVFTKDVKKAHMFARDIKAGTVWINQTNQEEAKVPFGGFKMSGIGRE 483
Query: 481 LGEYGLANFTNVKSVHVNL 499
G+ G+ N+ +KSVHV+L
Sbjct: 484 SGDTGVDNYLQIKSVHVDL 502
>Hs10835045 [C] KOG2450 Aldehyde dehydrogenase
Length = 518
Score = 428 bits (1101), Expect = e-120
Identities = 226/488 (46%), Positives = 313/488 (63%), Gaps = 16/488 (3%)
Query: 20 LFINNEYVEAHGSETLTSYNPSSGEEICKVQCADPKIDVDLAVKAARDAFP---GWKATP 76
+FINNE+ + YNP++GE++C+VQ AD K D+D AV+AAR AF W+
Sbjct: 40 IFINNEWQNSESGRVFPVYNPATGEQVCEVQEAD-KADIDKAVQAARLAFSLGSVWRRMD 98
Query: 77 AIEKRDLFYKLAGLLERDIDILSKIESLDTGKPIANNAKYDILEVVEVLKYYAGWIDKAG 136
A E+ L KLA L+ERD +L+ +ESL+ GKP D+ V++ +YYAGW DK
Sbjct: 99 ASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWADKIH 158
Query: 137 GQSFAPSSEKLAYTLHQPLGVVGCIIPFNYPLAMMSWKWT-AIATGNTTVFKSADQTPLS 195
G + + +T H+P+GV G IIP+N+PL M +WK A+ GNT V K A+QTPLS
Sbjct: 159 GMTIPVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQTPLS 218
Query: 196 ILYFAKLVKEAGFPAGVFNVLSGTGASVGSAIVKHTGVDKIAFTGSTAVGQIIQQQSA-V 254
LY L+KEAGFP GV N+L G G + G+AI H G+DKIAFTGST VG++IQ+ +
Sbjct: 219 ALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEAAGRS 278
Query: 255 NLKPITLECGGKSANMIFEDCDLEQAVKWSAWGIFNNMGQICSGTSRVFVQESIYEEFVA 314
NLK +TLE GGKS N+IF D DL+ AV+ + G+F N GQ C+ SR+FV+ESIYEEFV
Sbjct: 279 NLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIYEEFVR 338
Query: 315 QLADHVKKTYIVGAPSDDAVIVGPQVSKKQQERVLEYIKIGIEEGCKVPLGGLGAPEPIA 374
+ + K+ IVG+P D GPQ+ KKQ ++LE I+ G+ EG K+ GG G
Sbjct: 339 RSVERAKRR-IVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGKGLGR--- 394
Query: 375 NDPALANGYYVKPTILADVKASYRIAKEEIFGPVIVVGSFKDYKEALDIANDSDYGLGSA 434
G++++PT+ ++V RIAKEEIFGPV + FK E ++ AN+SD+GL +A
Sbjct: 395 ------KGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAA 448
Query: 435 IFSKDIVTCHKFAQDVEAGMVWINSSNDVDINVPFGGVKMSGHGRELGEYGLANFTNVKS 494
+F+ DI + ++AG VWIN N ++ PFGG KMSG+GRE+GE+GL ++ VK+
Sbjct: 449 VFTNDINKALTVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGLREYSEVKT 508
Query: 495 VHVNLGRK 502
V V + +K
Sbjct: 509 VTVKIPQK 516
>7297513 [C] KOG2450 Aldehyde dehydrogenase
Length = 520
Score = 422 bits (1086), Expect = e-118
Identities = 228/489 (46%), Positives = 321/489 (65%), Gaps = 16/489 (3%)
Query: 19 GLFINNEYVEAHGSETLTSYNPSSGEEICKVQCADPKIDVDLAVKAARDAFP---GWKAT 75
G+FINNE+ ++ + + NP++ E I ++QCAD K D+D+AV+AAR+AF W+
Sbjct: 41 GVFINNEWHKSKSGKIFETINPTTAEVIAEIQCAD-KEDIDIAVQAARNAFKLGSPWRRM 99
Query: 76 PAIEKRDLFYKLAGLLERDIDILSKIESLDTGKPIANNAKYDILEVVEVLKYYAGWIDKA 135
A E+ L Y+LA L+ERD L+ +E+LD GKP + + D+ ++ L+Y+AGW DK
Sbjct: 100 DASERGRLLYRLADLMERDQVYLASLETLDNGKPYSMSYNVDLPTAIKNLRYFAGWADKN 159
Query: 136 GGQSFAPSSEKLAYTLHQPLGVVGCIIPFNYPLAMMSWKW-TAIATGNTTVFKSADQTPL 194
G++ + YT H+P+GV G IIP+N+P+ MM+WK A+ATGNT V K A+QT L
Sbjct: 160 HGKTIPMDGDFFTYTRHEPVGVCGQIIPWNFPILMMAWKLGPALATGNTIVLKPAEQTSL 219
Query: 195 SILYFAKLVKEAGFPAGVFNVLSGTGASVGSAIVKHTGVDKIAFTGSTAVGQIIQQQSA- 253
+ LY A+LVKEAGFP GV NV+ G G + G+A+ H VDK+AFTGST VG++IQ S
Sbjct: 220 TALYIAQLVKEAGFPEGVVNVVPGFGTA-GAALANHCDVDKVAFTGSTDVGKLIQLASGN 278
Query: 254 VNLKPITLECGGKSANMIFEDCDLEQAVKWSAWGIFNNMGQICSGTSRVFVQESIYEEFV 313
NLK +TLE GGKS N+I D D++ AV+ + +G+F NMGQ C SR FV++ IY+EFV
Sbjct: 279 TNLKRVTLELGGKSPNIILSDTDMDYAVETAHFGLFFNMGQCCCAGSRTFVEDKIYDEFV 338
Query: 314 AQLADHVKKTYIVGAPSDDAVIVGPQVSKKQQERVLEYIKIGIEEGCKVPLGGLGAPEPI 373
+ A+ KK VG P D GPQV+++Q E++L IK G ++G K+ GG PE +
Sbjct: 339 ERSAERAKKR-TVGNPFDLNTEQGPQVNEEQMEKILGMIKTGKKQGAKLVAGG-SRPEGL 396
Query: 374 ANDPALANGYYVKPTILADVKASYRIAKEEIFGPVIVVGSFKDYKEALDIANDSDYGLGS 433
GY+V+PT+ ADV+ IA+EEIFGPV + FK E ++ AN+S+YGL +
Sbjct: 397 P-------GYFVQPTVFADVQDDMTIAREEIFGPVQQLIRFKKLDEVIERANNSEYGLAA 449
Query: 434 AIFSKDIVTCHKFAQDVEAGMVWINSSNDVDINVPFGGVKMSGHGRELGEYGLANFTNVK 493
A+F+KD+ + + AG VW+N+ N + PFGG KMSGHGRE GEY L+N+T VK
Sbjct: 450 AVFTKDLDKANYIVGGLRAGTVWVNTYNVLAAQAPFGGYKMSGHGRENGEYALSNYTEVK 509
Query: 494 SVHVNLGRK 502
SV V + +K
Sbjct: 510 SVIVKVAQK 518
>SPAC9E9.09c [C] KOG2450 Aldehyde dehydrogenase
Length = 503
Score = 414 bits (1063), Expect = e-115
Identities = 221/500 (44%), Positives = 311/500 (62%), Gaps = 17/500 (3%)
Query: 6 IKLADGTEYQQPLGLFINNEYVEAHGSETLTSYNPSSGEEICKVQCADPKIDVDLAVKAA 65
I + G Y QP+GLFINN++V++ + Y+PS+ + IC+V AD + DVD+AVK A
Sbjct: 11 ITVPTGKTYIQPVGLFINNQHVDSVHGGRVKVYSPSTEKLICEVADADEE-DVDIAVKVA 69
Query: 66 RDAFPG---WKATPAIEKRDLFYKLAGLLERDIDILSKIESLDTGKPIANNAKYDILEVV 122
R AF W+ + ++ +LA +E++++ L+ IE+LD GK I A+ D+
Sbjct: 70 RAAFQTDAPWRKFSSAQRGRCLSRLADCIEQNLEYLASIETLDNGKSITL-ARGDVQAAA 128
Query: 123 EVLKYYAGWIDKAGGQSFAPSSEKLAYTLHQPLGVVGCIIPFNYPLAMMSWKWT-AIATG 181
+ +YY GW DK GQ+ ++ AYT H+P+GV G IIP+N+P M +WK A+A G
Sbjct: 129 DCFRYYGGWADKDYGQTIETDIKRFAYTRHEPIGVCGQIIPWNFPFLMCAWKIAPAVACG 188
Query: 182 NTTVFKSADQTPLSILYFAKLVKEAGFPAGVFNVLSGTGASVGSAIVKHTGVDKIAFTGS 241
NT + K+A+ TPLS L K V E GFP GV NVLSG G G+AI H +DK+AFTGS
Sbjct: 189 NTIILKTAELTPLSALCLTKFVPECGFPPGVINVLSGDGRRCGNAISSHMDIDKVAFTGS 248
Query: 242 TAVGQIIQQQSAV-NLKPITLECGGKSANMIFEDCDLEQAVKWSAWGIFNNMGQICSGTS 300
T VG+++ + +A NLK +TLE GGKS N++F D DL+ A W+ +GIF N GQ+C S
Sbjct: 249 TGVGRMVMRAAASSNLKKVTLELGGKSPNIVFNDADLDSAAVWTNYGIFYNSGQVCCAGS 308
Query: 301 RVFVQESIYEEFVAQLADHVKKTYIVGAPSDDAVIVGPQVSKKQQERVLEYIKIGIEEGC 360
RV+VQE +Y+EF+ ++ K T VG P + G QVSK+Q ER++ YI+ GI G
Sbjct: 309 RVYVQEDVYDEFIKRMVAKAK-TLKVGDPFAEDTFQGAQVSKQQYERIVSYIESGIAHGA 367
Query: 361 KVPLGGLGAPEPIANDPALANGYYVKPTILADVKASYRIAKEEIFGPVIVVGSFKDYKEA 420
K+ +GG GY+V+PTIL++V + KEEIFGPV+ V FK +EA
Sbjct: 368 KLEIGGKRHGNL---------GYFVEPTILSNVTEDMAVGKEEIFGPVLAVIKFKTIEEA 418
Query: 421 LDIANDSDYGLGSAIFSKDIVTCHKFAQDVEAGMVWINSSNDVDINVPFGGVKMSGHGRE 480
+ N+S YGL + + + +I K + +EAG VW+N N + +PFGG K SG GRE
Sbjct: 419 IRRGNNSTYGLAAGVHTNNITNAIKVSNALEAGTVWVNCYNLLHHQIPFGGYKESGIGRE 478
Query: 481 LGEYGLANFTNVKSVHVNLG 500
LG YGL N+T K+VH+NLG
Sbjct: 479 LGSYGLTNYTQTKAVHINLG 498
>Hs11436533 [C] KOG2450 Aldehyde dehydrogenase
Length = 517
Score = 409 bits (1052), Expect = e-114
Identities = 226/488 (46%), Positives = 309/488 (63%), Gaps = 16/488 (3%)
Query: 20 LFINNEYVEAHGSETLTSYNPSSGEEICKVQCADPKIDVDLAVKAARDAFP---GWKATP 76
+FINNE+ +A +T + NPS+GE IC+V D K DVD AVKAAR AF W+
Sbjct: 39 IFINNEWHDAVSRKTFPTVNPSTGEVICQVAEGD-KEDVDKAVKAARAAFQLGSPWRRMD 97
Query: 77 AIEKRDLFYKLAGLLERDIDILSKIESLDTGKPIANNAKYDILEVVEVLKYYAGWIDKAG 136
A + L +LA L+ERD L+ +E+LD GKP + D+ V++ L+YYAGW DK
Sbjct: 98 ASHRGRLLNRLADLIERDRTYLAALETLDNGKPYVISYLVDLDMVLKCLRYYAGWADKYH 157
Query: 137 GQSFAPSSEKLAYTLHQPLGVVGCIIPFNYPLAMMSWKW-TAIATGNTTVFKSADQTPLS 195
G++ + +YT H+P+GV G IIP+N+PL M +WK A+ATGN V K A+QTPL+
Sbjct: 158 GKTIPIDGDFFSYTRHEPVGVCGQIIPWNFPLLMQAWKLGPALATGNVVVMKVAEQTPLT 217
Query: 196 ILYFAKLVKEAGFPAGVFNVLSGTGASVGSAIVKHTGVDKIAFTGSTAVGQIIQQQS-AV 254
LY A L+KEAGFP GV N++ G G + G+AI H VDK+AFTGST +G++IQ + +
Sbjct: 218 ALYVANLIKEAGFPPGVVNIVPGFGPTAGAAIASHEDVDKVAFTGSTEIGRVIQVAAGSS 277
Query: 255 NLKPITLECGGKSANMIFEDCDLEQAVKWSAWGIFNNMGQICSGTSRVFVQESIYEEFVA 314
NLK +TLE GGKS N+I D D++ AV+ + + +F N GQ C SR FVQE IY+EFV
Sbjct: 278 NLKRVTLELGGKSPNIIMSDADMDWAVEQAHFALFFNQGQCCCAGSRTFVQEDIYDEFVE 337
Query: 315 QLADHVKKTYIVGAPSDDAVIVGPQVSKKQQERVLEYIKIGIEEGCKVPLGGLGAPEPIA 374
+ K +VG P D GPQV + Q +++L YI G +EG K+ GG IA
Sbjct: 338 RSVARAKSR-VVGNPFDSKTEQGPQVDETQFKKILGYINTGKQEGAKLLCGG-----GIA 391
Query: 375 NDPALANGYYVKPTILADVKASYRIAKEEIFGPVIVVGSFKDYKEALDIANDSDYGLGSA 434
D GY+++PT+ DV+ IAKEEIFGPV+ + FK +E + AN+S YGL +A
Sbjct: 392 AD----RGYFIQPTVFGDVQDGMTIAKEEIFGPVMQILKFKTIEEVVGRANNSTYGLAAA 447
Query: 435 IFSKDIVTCHKFAQDVEAGMVWINSSNDVDINVPFGGVKMSGHGRELGEYGLANFTNVKS 494
+F+KD+ + +Q ++AG VW+N + PFGG KMSG GRELGEYGL +T VK+
Sbjct: 448 VFTKDLDKANYLSQALQAGTVWVNCYDVFGAQSPFGGYKMSGSGRELGEYGLQAYTEVKT 507
Query: 495 VHVNLGRK 502
V V + +K
Sbjct: 508 VTVKVPQK 515
>Hs19923115 [C] KOG2450 Aldehyde dehydrogenase
Length = 517
Score = 409 bits (1051), Expect = e-114
Identities = 225/488 (46%), Positives = 311/488 (63%), Gaps = 16/488 (3%)
Query: 20 LFINNEYVEAHGSETLTSYNPSSGEEICKVQCADPKIDVDLAVKAARDAF---PGWKATP 76
LFINNE+ +A +T + NP++GE I V D + DVD AVKAAR+AF W+
Sbjct: 39 LFINNEWQDAVSKKTFPTVNPTTGEVIGHVAEGD-RADVDRAVKAAREAFRLGSPWRRMD 97
Query: 77 AIEKRDLFYKLAGLLERDIDILSKIESLDTGKPIANNAKYDILEVVEVLKYYAGWIDKAG 136
A E+ L LA L+ERD L+ +E+LD GKP + D+ EV++V +Y+AGW DK
Sbjct: 98 ASERGRLLNLLADLVERDRVYLASLETLDNGKPFQESYALDLDEVIKVYRYFAGWADKWH 157
Query: 137 GQSFAPSSEKLAYTLHQPLGVVGCIIPFNYPLAMMSWKWT-AIATGNTTVFKSADQTPLS 195
G++ + +T H+P+GV G IIP+N+PL M WK A+ATGNT V K A+QTPLS
Sbjct: 158 GKTIPMDGQHFCFTRHEPVGVCGQIIPWNFPLVMQGWKLAPALATGNTVVMKVAEQTPLS 217
Query: 196 ILYFAKLVKEAGFPAGVFNVLSGTGASVGSAIVKHTGVDKIAFTGSTAVGQIIQQQSA-V 254
LY A L+KEAGFP GV N+++G G + G+AI +H VDK+AFTGST VG +IQ+ +
Sbjct: 218 ALYLASLIKEAGFPPGVVNIITGYGPTAGAAIAQHMDVDKVAFTGSTEVGHLIQKAAGDS 277
Query: 255 NLKPITLECGGKSANMIFEDCDLEQAVKWSAWGIFNNMGQICSGTSRVFVQESIYEEFVA 314
NLK +TLE GGKS +++ D D+E AV+ +F NMGQ C SR FV+ESIY EF+
Sbjct: 278 NLKRVTLELGGKSPSIVLADADMEHAVEQCHEALFFNMGQCCCAGSRTFVEESIYNEFLE 337
Query: 315 QLADHVKKTYIVGAPSDDAVIVGPQVSKKQQERVLEYIKIGIEEGCKVPLGGLGAPEPIA 374
+ + K+ VG P + GPQV K+Q ERVL YI++G +EG K+ GG E
Sbjct: 338 RTVEKAKQRK-VGNPFELDTQQGPQVDKEQFERVLGYIQLGQKEGAKLLCGGERFGE--- 393
Query: 375 NDPALANGYYVKPTILADVKASYRIAKEEIFGPVIVVGSFKDYKEALDIANDSDYGLGSA 434
G+++KPT+ V+ RIAKEEIFGPV + FK +E ++ AN++ YGL +A
Sbjct: 394 ------RGFFIKPTVFGGVQDDMRIAKEEIFGPVQPLFKFKKIEEVVERANNTRYGLAAA 447
Query: 435 IFSKDIVTCHKFAQDVEAGMVWINSSNDVDINVPFGGVKMSGHGRELGEYGLANFTNVKS 494
+F++D+ F Q ++AG VW+N+ N V + PFGG K SG+GRELGE GL +T VK+
Sbjct: 448 VFTRDLDKAMYFTQALQAGTVWVNTYNIVTCHTPFGGFKESGNGRELGEDGLKAYTEVKT 507
Query: 495 VHVNLGRK 502
V + + +K
Sbjct: 508 VTIKVPQK 515
>Hs4502041 [C] KOG2450 Aldehyde dehydrogenase
Length = 512
Score = 404 bits (1037), Expect = e-112
Identities = 215/488 (44%), Positives = 310/488 (63%), Gaps = 16/488 (3%)
Query: 20 LFINNEYVEAHGSETLTSYNPSSGEEICKVQCADPKIDVDLAVKAARDAFPG---WKATP 76
+FINNE+ E+ + + NPS+ E+IC+V+ D K DVD AV+AA+ AF W+
Sbjct: 34 IFINNEWHESKSGKKFATCNPSTREQICEVEEGD-KPDVDKAVEAAQVAFQRGSPWRRLD 92
Query: 77 AIEKRDLFYKLAGLLERDIDILSKIESLDTGKPIANNAKYDILEVVEVLKYYAGWIDKAG 136
A+ + L ++LA L+ERD L+ +E++DTGKP + D+ + L+Y+AGW DK
Sbjct: 93 ALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWADKIQ 152
Query: 137 GQSFAPSSEKLAYTLHQPLGVVGCIIPFNYPLAMMSWKWT-AIATGNTTVFKSADQTPLS 195
G++ + +T H+P+GV G I P+N+PL M+ WK A+ GNT V K A+QTPL+
Sbjct: 153 GKTIPTDDNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQTPLT 212
Query: 196 ILYFAKLVKEAGFPAGVFNVLSGTGASVGSAIVKHTGVDKIAFTGSTAVGQIIQQQ-SAV 254
LY L+KEAGFP GV N++ G G +VG+AI H ++KIAFTGST VG+++++ S
Sbjct: 213 ALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAASRS 272
Query: 255 NLKPITLECGGKSANMIFEDCDLEQAVKWSAWGIFNNMGQICSGTSRVFVQESIYEEFVA 314
NLK +TLE GGK+ ++ D DL+ AV+ + G+F N GQ C+ SRVFV+E +Y EFV
Sbjct: 273 NLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYSEFVR 332
Query: 315 QLADHVKKTYIVGAPSDDAVIVGPQVSKKQQERVLEYIKIGIEEGCKVPLGGLGAPEPIA 374
+ ++ KK VG P D GPQ+ +KQ +++LE I+ G +EG K+ GG +
Sbjct: 333 RSVEYAKKRP-VGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSAMED--- 388
Query: 375 NDPALANGYYVKPTILADVKASYRIAKEEIFGPVIVVGSFKDYKEALDIANDSDYGLGSA 434
G ++KPT+ ++V + RIAKEEIFGPV + FK +E + AN +DYGL +A
Sbjct: 389 ------KGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAA 442
Query: 435 IFSKDIVTCHKFAQDVEAGMVWINSSNDVDINVPFGGVKMSGHGRELGEYGLANFTNVKS 494
+F+K++ K A +E+G VWIN N + PFGG KMSG+GRELGEY LA +T VK+
Sbjct: 443 VFTKNLDKALKLASALESGTVWINCYNALYAQAPFGGFKMSGNGRELGEYALAEYTEVKT 502
Query: 495 VHVNLGRK 502
V + LG K
Sbjct: 503 VTIKLGDK 510
>HsM4502031 [C] KOG2450 Aldehyde dehydrogenase
Length = 501
Score = 403 bits (1035), Expect = e-112
Identities = 215/488 (44%), Positives = 309/488 (63%), Gaps = 16/488 (3%)
Query: 20 LFINNEYVEAHGSETLTSYNPSSGEEICKVQCADPKIDVDLAVKAARDAFP---GWKATP 76
+FINNE+ ++ + +NP++ EE+C+V+ D K DVD AVKAAR AF W+
Sbjct: 23 IFINNEWHDSVSGKKFPVFNPATEEELCQVEEGD-KEDVDKAVKAARQAFQIGSPWRTMD 81
Query: 77 AIEKRDLFYKLAGLLERDIDILSKIESLDTGKPIANNAKYDILEVVEVLKYYAGWIDKAG 136
A E+ L YKLA L+ERD +L+ +ES++ GK +N D+ ++ L+Y AGW DK
Sbjct: 82 ASERGRLLYKLADLIERDRLLLATMESMNGGKLYSNAYLSDLAGCIKTLRYCAGWADKIQ 141
Query: 137 GQSFAPSSEKLAYTLHQPLGVVGCIIPFNYPLAMMSWK-WTAIATGNTTVFKSADQTPLS 195
G++ YT H+P+GV G IIP+N+PL M+ WK A++ GNT V K A+QTPL+
Sbjct: 142 GRTIPIDGNFFTYTRHEPIGVCGQIIPWNFPLVMLIWKIGPALSCGNTVVVKPAEQTPLT 201
Query: 196 ILYFAKLVKEAGFPAGVFNVLSGTGASVGSAIVKHTGVDKIAFTGSTAVGQIIQQQSAV- 254
L+ A L+KEAGFP GV N++ G G + G+AI H +DK+AFTGST VG++I++ +
Sbjct: 202 ALHVASLIKEAGFPPGVVNIVPGYGPTAGAAISSHMDIDKVAFTGSTEVGKLIKEAAGKS 261
Query: 255 NLKPITLECGGKSANMIFEDCDLEQAVKWSAWGIFNNMGQICSGTSRVFVQESIYEEFVA 314
NLK +TLE GGKS ++ D DL+ AV+++ G+F + GQ C SR+FV+ESIY+EFV
Sbjct: 262 NLKRVTLELGGKSPCIVLADADLDNAVEFAHHGVFYHQGQCCIAASRIFVEESIYDEFVR 321
Query: 315 QLADHVKKTYIVGAPSDDAVIVGPQVSKKQQERVLEYIKIGIEEGCKVPLGGLGAPEPIA 374
+ + KK YI+G P V GPQ+ K+Q +++L+ I+ G +EG K+ GG
Sbjct: 322 RSVERAKK-YILGNPLTPGVTQGPQIDKEQYDKILDLIESGKKEGAKLECGG-------- 372
Query: 375 NDPALANGYYVKPTILADVKASYRIAKEEIFGPVIVVGSFKDYKEALDIANDSDYGLGSA 434
P GY+V+PT+ ++V RIAKEEIFGPV + FK + + AN++ YGL +
Sbjct: 373 -GPWGNKGYFVQPTVFSNVTDEMRIAKEEIFGPVQQIMKFKSLDDVIKRANNTFYGLSAG 431
Query: 435 IFSKDIVTCHKFAQDVEAGMVWINSSNDVDINVPFGGVKMSGHGRELGEYGLANFTNVKS 494
+F+KDI + ++AG VW+N V PFGG KMSG+GRELGEYG +T VK+
Sbjct: 432 VFTKDIDKAITISSALQAGTVWVNCYGVVSAQCPFGGFKMSGNGRELGEYGFHEYTEVKT 491
Query: 495 VHVNLGRK 502
V V + +K
Sbjct: 492 VTVKISQK 499
>Hs21361176 [C] KOG2450 Aldehyde dehydrogenase
Length = 501
Score = 403 bits (1035), Expect = e-112
Identities = 215/488 (44%), Positives = 309/488 (63%), Gaps = 16/488 (3%)
Query: 20 LFINNEYVEAHGSETLTSYNPSSGEEICKVQCADPKIDVDLAVKAARDAFP---GWKATP 76
+FINNE+ ++ + +NP++ EE+C+V+ D K DVD AVKAAR AF W+
Sbjct: 23 IFINNEWHDSVSGKKFPVFNPATEEELCQVEEGD-KEDVDKAVKAARQAFQIGSPWRTMD 81
Query: 77 AIEKRDLFYKLAGLLERDIDILSKIESLDTGKPIANNAKYDILEVVEVLKYYAGWIDKAG 136
A E+ L YKLA L+ERD +L+ +ES++ GK +N D+ ++ L+Y AGW DK
Sbjct: 82 ASERGRLLYKLADLIERDRLLLATMESMNGGKLYSNAYLNDLAGCIKTLRYCAGWADKIQ 141
Query: 137 GQSFAPSSEKLAYTLHQPLGVVGCIIPFNYPLAMMSWK-WTAIATGNTTVFKSADQTPLS 195
G++ YT H+P+GV G IIP+N+PL M+ WK A++ GNT V K A+QTPL+
Sbjct: 142 GRTIPIDGNFFTYTRHEPIGVCGQIIPWNFPLVMLIWKIGPALSCGNTVVVKPAEQTPLT 201
Query: 196 ILYFAKLVKEAGFPAGVFNVLSGTGASVGSAIVKHTGVDKIAFTGSTAVGQIIQQQSAV- 254
L+ A L+KEAGFP GV N++ G G + G+AI H +DK+AFTGST VG++I++ +
Sbjct: 202 ALHVASLIKEAGFPPGVVNIVPGYGPTAGAAISSHMDIDKVAFTGSTEVGKLIKEAAGKS 261
Query: 255 NLKPITLECGGKSANMIFEDCDLEQAVKWSAWGIFNNMGQICSGTSRVFVQESIYEEFVA 314
NLK +TLE GGKS ++ D DL+ AV+++ G+F + GQ C SR+FV+ESIY+EFV
Sbjct: 262 NLKRVTLELGGKSPCIVLADADLDNAVEFAHHGVFYHQGQCCIAASRIFVEESIYDEFVR 321
Query: 315 QLADHVKKTYIVGAPSDDAVIVGPQVSKKQQERVLEYIKIGIEEGCKVPLGGLGAPEPIA 374
+ + KK YI+G P V GPQ+ K+Q +++L+ I+ G +EG K+ GG
Sbjct: 322 RSVERAKK-YILGNPLTPGVTQGPQIDKEQYDKILDLIESGKKEGAKLECGG-------- 372
Query: 375 NDPALANGYYVKPTILADVKASYRIAKEEIFGPVIVVGSFKDYKEALDIANDSDYGLGSA 434
P GY+V+PT+ ++V RIAKEEIFGPV + FK + + AN++ YGL +
Sbjct: 373 -GPWGNKGYFVQPTVFSNVTDEMRIAKEEIFGPVQQIMKFKSLDDVIKRANNTFYGLSAG 431
Query: 435 IFSKDIVTCHKFAQDVEAGMVWINSSNDVDINVPFGGVKMSGHGRELGEYGLANFTNVKS 494
+F+KDI + ++AG VW+N V PFGG KMSG+GRELGEYG +T VK+
Sbjct: 432 VFTKDIDKAITISSALQAGTVWVNCYGVVSAQCPFGGFKMSGNGRELGEYGFHEYTEVKT 491
Query: 495 VHVNLGRK 502
V V + +K
Sbjct: 492 VTVKISQK 499
>YOR374w [C] KOG2450 Aldehyde dehydrogenase
Length = 519
Score = 399 bits (1025), Expect = e-111
Identities = 218/497 (43%), Positives = 306/497 (60%), Gaps = 15/497 (3%)
Query: 6 IKLADGTEYQQPLGLFINNEYVEAHGSETLTSYNPSSGEEICKVQCADPKIDVDLAVKAA 65
IKL +G EY+QP GLFINN++V + ++T NPS+ EEIC + + DV+ AV+AA
Sbjct: 33 IKLPNGLEYEQPTGLFINNKFVPSKQNKTFEVINPSTEEEICHIY-EGREDDVEEAVQAA 91
Query: 66 RDAFPG--WKATPAIEKRDLFYKLAGLLERDIDILSKIESLDTGKPIANNAKYDILEVVE 123
AF W I++ Y+LA L+E+D D+++ IE+LD GK I+++ + D+ V+
Sbjct: 92 DRAFSNGSWNGIDPIDRGKALYRLAELIEQDKDVIASIETLDNGKAISSS-RGDVDLVIN 150
Query: 124 VLKYYAGWIDKAGGQSFAPSSEKLAYTLHQPLGVVGCIIPFNYPLAMMSWKWT-AIATGN 182
LK AG+ DK G+ +YT QPLGV G IIP+N+PL M +WK A+ TGN
Sbjct: 151 YLKSSAGFADKIDGRMIDTGRTHFSYTKRQPLGVCGQIIPWNFPLLMWAWKIAPALVTGN 210
Query: 183 TTVFKSADQTPLSILYFAKLVKEAGFPAGVFNVLSGTGASVGSAIVKHTGVDKIAFTGST 242
T V K+A+ TPLS LY +K + +AG P GV N++SG G VG AI H + K+AFTGST
Sbjct: 211 TVVLKTAESTPLSALYVSKYIPQAGIPPGVINIVSGFGKIVGEAITNHPKIKKVAFTGST 270
Query: 243 AVGQIIQQQSAVNLKPITLECGGKSANMIFEDCDLEQAVKWSAWGIFNNMGQICSGTSRV 302
A G+ I Q +A LK +TLE GGKS N++F D +L++AV+ GI+ N G++C SRV
Sbjct: 271 ATGRHIYQSAAAGLKKVTLELGGKSPNIVFADAELKKAVQNIILGIYYNSGEVCCAGSRV 330
Query: 303 FVQESIYEEFVAQLADHVKKTYIVGAPSDDAVIVGPQVSKKQQERVLEYIKIGIEEGCKV 362
+V+ESIY++F+ + ++ VG P D++ G Q S+ Q ++L+Y+ IG EG +
Sbjct: 331 YVEESIYDKFIEEF-KAASESIKVGDPFDESTFQGAQTSQMQLNKILKYVDIGKNEGATL 389
Query: 363 PLGGLGAPEPIANDPALANGYYVKPTILADVKASYRIAKEEIFGPVIVVGSFKDYKEALD 422
GG + + GY++KPT+ DVK RI KEEIFGPV+ V FK E ++
Sbjct: 390 ITGG---------ERLGSKGYFIKPTVFGDVKEDMRIVKEEIFGPVVTVTKFKSADEVIN 440
Query: 423 IANDSDYGLGSAIFSKDIVTCHKFAQDVEAGMVWINSSNDVDINVPFGGVKMSGHGRELG 482
+ANDS+YGL + I + +I T K A V AG VWIN+ ND VPFGG SG GRE+
Sbjct: 441 MANDSEYGLAAGIHTSNINTALKVADRVNAGTVWINTYNDFHHAVPFGGFNASGLGREMS 500
Query: 483 EYGLANFTNVKSVHVNL 499
L N+ VK+V L
Sbjct: 501 VDALQNYLQVKAVRAKL 517
>Hs4502033 [C] KOG2450 Aldehyde dehydrogenase
Length = 516
Score = 399 bits (1025), Expect = e-111
Identities = 221/488 (45%), Positives = 304/488 (62%), Gaps = 16/488 (3%)
Query: 20 LFINNEYVEAHGSETLTSYNPSSGEEICKVQCADPKIDVDLAVKAARDAFP---GWKATP 76
+FINNE+ +A +T + NPS+GE IC+V D K DVD A + AF W+
Sbjct: 38 IFINNEWHDAVSRKTFPTVNPSTGEVICQVAEGD-KEDVDKAREGRPGAFQLGSPWRRMD 96
Query: 77 AIEKRDLFYKLAGLLERDIDILSKIESLDTGKPIANNAKYDILEVVEVLKYYAGWIDKAG 136
A L +LA L+ERD L+ +E+LD GKP + D+ V++ L+YYAGW DK
Sbjct: 97 ASHSGRLLNRLADLIERDRTYLAALETLDNGKPYVISYLVDLDMVLKCLRYYAGWADKYH 156
Query: 137 GQSFAPSSEKLAYTLHQPLGVVGCIIPFNYPLAMMSWKW-TAIATGNTTVFKSADQTPLS 195
G++ + +YT H+P+GV G IIP+N+PL M +WK A+ATGN V K A+QTPL+
Sbjct: 157 GKTIPIDGDFFSYTRHEPVGVCGQIIPWNFPLLMQAWKLGPALATGNVVVMKVAEQTPLT 216
Query: 196 ILYFAKLVKEAGFPAGVFNVLSGTGASVGSAIVKHTGVDKIAFTGSTAVGQIIQQQS-AV 254
LY A L+KEAGFP GV N++ G G + G+AI H VDK+AFTGST +G++IQ + +
Sbjct: 217 ALYVANLIKEAGFPPGVVNIVPGFGPTAGAAIASHEDVDKVAFTGSTEIGRVIQVAAGSS 276
Query: 255 NLKPITLECGGKSANMIFEDCDLEQAVKWSAWGIFNNMGQICSGTSRVFVQESIYEEFVA 314
NLK +TLE GGKS N+I D D++ AV+ + + +F N GQ C SR FVQE IY+EFV
Sbjct: 277 NLKRVTLELGGKSPNIIMSDADMDWAVEQAHFALFFNQGQCCCAGSRTFVQEDIYDEFVV 336
Query: 315 QLADHVKKTYIVGAPSDDAVIVGPQVSKKQQERVLEYIKIGIEEGCKVPLGGLGAPEPIA 374
+ K +VG P D GPQV + Q +++L YI G +EG K+ GG IA
Sbjct: 337 RSVARAKSR-VVGNPFDSKTEQGPQVDETQFKKILGYINTGKQEGAKLLCGG-----GIA 390
Query: 375 NDPALANGYYVKPTILADVKASYRIAKEEIFGPVIVVGSFKDYKEALDIANDSDYGLGSA 434
D GY+++PT+ DV+ IAKEEIFGPV+ + FK +E + AN+S YGL +A
Sbjct: 391 AD----RGYFIQPTVFGDVQDGMTIAKEEIFGPVMQILKFKTIEEVVGRANNSTYGLAAA 446
Query: 435 IFSKDIVTCHKFAQDVEAGMVWINSSNDVDINVPFGGVKMSGHGRELGEYGLANFTNVKS 494
+F+KD+ + +Q ++AG VW+N + PFGG KMSG GRELGEYGL +T VK+
Sbjct: 447 VFTKDLDKANYLSQALQAGTVWVNCYDVFGAQSPFGGYKMSGSGRELGEYGLQAYTEVKT 506
Query: 495 VHVNLGRK 502
V V + +K
Sbjct: 507 VTVKVPQK 514
>CE23852 [C] KOG2450 Aldehyde dehydrogenase
Length = 537
Score = 395 bits (1016), Expect = e-110
Identities = 215/488 (44%), Positives = 306/488 (62%), Gaps = 16/488 (3%)
Query: 20 LFINNEYVEAHGSETLTSYNPSSGEEICKVQCADPKIDVDLAVKAARDAFP---GWKATP 76
LFINNE+V+A +T NP++G+ + KV + + DVD+AV+AA+ AF W+
Sbjct: 59 LFINNEFVDAKSGKTFEFVNPANGKLLAKVAEGN-RDDVDIAVEAAKKAFKIGSEWRRMD 117
Query: 77 AIEKRDLFYKLAGLLERDIDILSKIESLDTGKPIANNAKYDILEVVEVLKYYAGWIDKAG 136
A + L +LA L+ERD IL+ +ESLD GKP D+ ++ +YYAG+ DK
Sbjct: 118 ASHRGVLLNRLADLMERDRVILASLESLDNGKPYKEAYNIDLPISIKTFRYYAGYADKNH 177
Query: 137 GQSFAPSSEKLAYTLHQPLGVVGCIIPFNYPLAMMSWKWT-AIATGNTTVFKSADQTPLS 195
G++ + YT H+P+GV G IIP+N+PL M +WK A+A GNT V K A +TPLS
Sbjct: 178 GKTIPVGGDYFTYTRHEPVGVCGQIIPWNFPLLMQAWKLAPALAMGNTVVMKVAVKTPLS 237
Query: 196 ILYFAKLVKEAGFPAGVFNVLSGTGASVGSAIVKHTGVDKIAFTGSTAVGQIIQQQSAV- 254
L+ A L+KEA FP GV N++ G G G AI H VDK+AFTGST VG+ I + +A
Sbjct: 238 ALHVASLIKEAQFPEGVVNIIPGRGTDAGEAIASHMDVDKVAFTGSTEVGKTIMKAAAES 297
Query: 255 NLKPITLECGGKSANMIFEDCDLEQAVKWSAWGIFNNMGQICSGTSRVFVQESIYEEFVA 314
N+K +TLE GGKS N++F D DLE+AV+ S +F N GQ CS SR FV+ IY+EFVA
Sbjct: 298 NVKKVTLELGGKSPNIVFADADLEEAVRQSHHALFFNQGQCCSAGSRTFVEGKIYDEFVA 357
Query: 315 QLADHVKKTYIVGAPSDDAVIVGPQVSKKQQERVLEYIKIGIEEGCKVPLGGLGAPEPIA 374
+ + V+KT ++G P D+ GPQ+ + Q E +++YI+ G +EG ++ GG+ +
Sbjct: 358 KAKELVEKT-VIGDPFDENTTQGPQIDESQVETIMKYIESGKKEGAQLVTGGVKHGD--- 413
Query: 375 NDPALANGYYVKPTILADVKASYRIAKEEIFGPVIVVGSFKDYKEALDIANDSDYGLGSA 434
GY+VKPTI A+V +IA+EEIFGPV++V F +E ++ AN++ YGL +
Sbjct: 414 ------QGYFVKPTIFANVNDQMKIAQEEIFGPVMIVIRFDSMEELIEKANNTIYGLAAG 467
Query: 435 IFSKDIVTCHKFAQDVEAGMVWINSSNDVDINVPFGGVKMSGHGRELGEYGLANFTNVKS 494
+ + D+ + A + AG VW+N + D PFGG K SG GRELGEYGLA +T VK+
Sbjct: 468 VVTNDLNKALQVANTIRAGSVWVNCYDVFDPAAPFGGFKQSGIGRELGEYGLAAYTEVKT 527
Query: 495 VHVNLGRK 502
V + + +K
Sbjct: 528 VTIKVPQK 535
>YER073w [C] KOG2450 Aldehyde dehydrogenase
Length = 520
Score = 387 bits (993), Expect = e-107
Identities = 214/500 (42%), Positives = 302/500 (59%), Gaps = 14/500 (2%)
Query: 6 IKLADGTEYQQPLGLFINNEYVEAHGSETLTSYNPSSGEEICKVQCADPKIDVDLAVKAA 65
I L +G Y+QP GLFIN E+V + +T NPS+ E+I V A + DVD AV AA
Sbjct: 32 ITLPNGFTYEQPTGLFINGEFVASKQKKTFDVINPSNEEKITTVYKA-MEDDVDEAVAAA 90
Query: 66 RDAFPG-WKATPAIEKRDLFYKLAGLLERDIDILSKIESLDTGKPIANNAKYDILEVVEV 124
+ AF W + + LA L+E+ + L+ IES+D GK + A+ D+ V +
Sbjct: 91 KKAFETKWSIVEPEVRAKALFNLADLVEKHQETLAAIESMDNGKSLFC-ARGDVALVSKY 149
Query: 125 LKYYAGWIDKAGGQSFAPSSEKLAYTLHQPLGVVGCIIPFNYPLAMMSWK-WTAIATGNT 183
L+ GW DK G Y++ +PLGV G IIP+N+PL M SWK A+ATGNT
Sbjct: 150 LRSCGGWADKIYGNVIDTGKNHFTYSIKEPLGVCGQIIPWNFPLLMWSWKIGPALATGNT 209
Query: 184 TVFKSADQTPLSILYFAKLVKEAGFPAGVFNVLSGTGASVGSAIVKHTGVDKIAFTGSTA 243
V K A+ TPLS L+ ++L +EAG PAGV N+L G+G VG + H V KIAFTGSTA
Sbjct: 210 VVLKPAETTPLSALFASQLCQEAGIPAGVVNILPGSGRVVGERLSAHPDVKKIAFTGSTA 269
Query: 244 VGQIIQQQSAVNLKPITLECGGKSANMIFEDCDLEQAVKWSAWGIFNNMGQICSGTSRVF 303
G+ I + +A +K +TLE GGKS N++F D DL++AVK A+GIF N G++C SR++
Sbjct: 270 TGRHIMKVAADTVKKVTLELGGKSPNIVFADADLDKAVKNIAFGIFYNSGEVCCAGSRIY 329
Query: 304 VQESIYEEFVAQLADHVKKTYIVGAPSDDAVIVGPQVSKKQQERVLEYIKIGIEEGCKVP 363
+Q+++YEE + +L D+ ++ VG P D+ V G Q S KQ ++L+Y+ + EG ++
Sbjct: 330 IQDTVYEEVLQKLKDYT-ESLKVGDPFDEEVFQGAQTSDKQLHKILDYVDVAKSEGARLV 388
Query: 364 LGGLGAPEPIANDPALANGYYVKPTILADVKASYRIAKEEIFGPVIVVGSFKDYKEALDI 423
GG + GY+VKPT+ ADVK RI KEE+FGP++ V F E + +
Sbjct: 389 TGGARHG---------SKGYFVKPTVFADVKGDMRIVKEEVFGPIVTVSKFSTVDEVIAM 439
Query: 424 ANDSDYGLGSAIFSKDIVTCHKFAQDVEAGMVWINSSNDVDINVPFGGVKMSGHGRELGE 483
ANDS YGL + I + DI ++ V+AG VWIN+ N+ NVPFGG SG GRE+GE
Sbjct: 440 ANDSQYGLAAGIHTNDINKAVDVSKRVKAGTVWINTYNNFHQNVPFGGFGQSGIGREMGE 499
Query: 484 YGLANFTNVKSVHVNLGRKL 503
L+N+T KSV + + + +
Sbjct: 500 AALSNYTQTKSVRIAIDKPI 519
>7301524 [C] KOG2450 Aldehyde dehydrogenase
Length = 659
Score = 385 bits (990), Expect = e-107
Identities = 216/502 (43%), Positives = 313/502 (62%), Gaps = 18/502 (3%)
Query: 3 FTSIKLADGTEYQQPLGLFINNEYVEAHGSETLTSYNPSSGEEICKVQCADPKIDVDLAV 62
+ S+ +AD + LFINNE+V++ +T ++NP++ +EI +V D K D+DLAV
Sbjct: 170 YISLNMADPNAKPKYTKLFINNEFVDSVSGKTFATFNPATSKEIVQVSEGD-KADIDLAV 228
Query: 63 KAARDAF---PGWKATPAIEKRDLFYKLAGLLERDIDILSKIESLDTGKPIANNAKYDIL 119
KAA+ AF W+ +++ +L KL L++RD L+ +E+ D GKP A A +D+
Sbjct: 229 KAAKKAFHRDSEWRKLSPLQRTNLMNKLCALMDRDKAFLASLETQDNGKPYAE-ALFDVT 287
Query: 120 EVVEVLKYYAGWIDKAGGQSFAPSSEKLAYTLHQPLGVVGCIIPFNYPLAMMSWKW-TAI 178
+ L+YYAGW DK G + P+ ++ T +P+GVVG IIP+NYPL M++WKW A+
Sbjct: 288 YSILTLQYYAGWTDKFFGDTI-PAGGFVSMTRKEPVGVVGQIIPWNYPLLMLAWKWGPAL 346
Query: 179 ATGNTTVFKSADQTPLSILYFAKLVKEAGFPAGVFNVLSGTGASVGSAIVKHTGVDKIAF 238
A G T + K A+QTPL+ L+ A L KEAGFPAGV NV++G G + G+AI H + K+AF
Sbjct: 347 AVGCTIIMKPAEQTPLTALHMAALAKEAGFPAGVINVVNGFGPTAGAAISAHPDIAKVAF 406
Query: 239 TGSTAVGQIIQQQSAV-NLKPITLECGGKSANMIFEDCDLEQAVKWSAWGIFNNMGQICS 297
TGS +G+I+ Q +A NLK ++LE GGKS ++F+D D++ AV+ + +F+N GQ C
Sbjct: 407 TGSVEIGRIVMQAAATSNLKRVSLELGGKSPVVVFDDADIDFAVETTHEALFSNHGQSCC 466
Query: 298 GTSRVFVQESIYEEFVAQLADHVKKTYIVGAPSDDAVIVGPQVSKKQQERVLEYIKIGIE 357
SR +V E IY+EFVA+ A K VG P + V GPQ+ +VL YI+ G +
Sbjct: 467 AGSRTYVHEKIYDEFVAKAAAKAKARK-VGNPFEQNVQQGPQIDDDMLTKVLGYIESGKK 525
Query: 358 EGCKVPLGGLGAPEPIANDPALANGYYVKPTILADVKASYRIAKEEIFGPVIVVGSFKDY 417
EG K+ GG + I N G++V+PT+ +DVK RIA+EEIFGPV + F
Sbjct: 526 EGAKLQAGG----KRIGNV-----GFFVEPTVFSDVKDDMRIAQEEIFGPVQSIFKFSSL 576
Query: 418 KEALDIANDSDYGLGSAIFSKDIVTCHKFAQDVEAGMVWINSSNDVDINVPFGGVKMSGH 477
+E +D AN+ YGL + + + DI KFA +V+AG VWIN + V + PFGG K SG
Sbjct: 577 EEMIDRANNVQYGLAAGVITNDINKALKFANNVDAGSVWINCYDAVLPSTPFGGYKHSGI 636
Query: 478 GRELGEYGLANFTNVKSVHVNL 499
GRELG+ GL N+ K++ + L
Sbjct: 637 GRELGKDGLDNYLETKTITMKL 658
>At1g23800 [C] KOG2450 Aldehyde dehydrogenase
Length = 508
Score = 379 bits (972), Expect = e-105
Identities = 207/484 (42%), Positives = 293/484 (59%), Gaps = 15/484 (3%)
Query: 20 LFINNEYVEAHGSETLTSYNPSSGEEICKVQCADPKIDVDLAVKAARDAFPG--WKATPA 77
L I +V+A +T + +P +GE I +V D + DV+ AV AAR AF W A
Sbjct: 30 LLIGGRFVDAVSGKTFPTLDPRNGEVIAQVSEGDAE-DVNRAVAAARKAFDEGPWPKMTA 88
Query: 78 IEKRDLFYKLAGLLERDIDILSKIESLDTGKPIANNAKYDILEVVEVLKYYAGWIDKAGG 137
E+ + ++ A L+E+ D ++ +E+ D GKP +A+ ++ + V +YYAGW DK G
Sbjct: 89 YERSKILFRFADLIEKHNDEIAALETWDNGKPYEQSAQIEVPMLARVFRYYAGWADKIHG 148
Query: 138 QSFAPSSEKLAYTLHQPLGVVGCIIPFNYPLAMMSWKW-TAIATGNTTVFKSADQTPLSI 196
+ TLH+P+GV G IIP+N+PL M+SWK A+A GNT V K+A+QTPLS
Sbjct: 149 MTMPGDGPHHVQTLHEPIGVAGQIIPWNFPLLMLSWKLGPALACGNTVVLKTAEQTPLSA 208
Query: 197 LYFAKLVKEAGFPAGVFNVLSGTGASVGSAIVKHTGVDKIAFTGSTAVGQIIQQ-QSAVN 255
L KL+ EAG P GV N++SG GA+ G+AI H VDK+AFTGST VG+II + S N
Sbjct: 209 LLVGKLLHEAGLPDGVVNIVSGFGATAGAAIASHMDVDKVAFTGSTDVGKIILELASKSN 268
Query: 256 LKPITLECGGKSANMIFEDCDLEQAVKWSAWGIFNNMGQICSGTSRVFVQESIYEEFVAQ 315
LK +TLE GGKS ++ ED D++QAV+ + + +F N GQ C SR FV E +Y+EFV +
Sbjct: 269 LKAVTLELGGKSPFIVCEDADVDQAVELAHFALFFNQGQCCCAGSRTFVHERVYDEFVEK 328
Query: 316 LADHVKKTYIVGAPSDDAVIVGPQVSKKQQERVLEYIKIGIEEGCKVPLGGLGAPEPIAN 375
K VG P + GPQV +Q ++L+YIK G+E G + GG
Sbjct: 329 AKARALKRN-VGDPFKSGIEQGPQVDSEQFNKILKYIKHGVEAGATLQAGG--------- 378
Query: 376 DPALANGYYVKPTILADVKASYRIAKEEIFGPVIVVGSFKDYKEALDIANDSDYGLGSAI 435
D + GYY++PT+ +DVK IA +EIFGPV + FKD E + AN+S YGL + +
Sbjct: 379 DRLGSKGYYIQPTVFSDVKDDMLIATDEIFGPVQTILKFKDLDEVIARANNSRYGLAAGV 438
Query: 436 FSKDIVTCHKFAQDVEAGMVWINSSNDVDINVPFGGVKMSGHGRELGEYGLANFTNVKSV 495
F++++ T H+ + + G VWIN + +D ++PFGG KMSG GRE G Y L N+ VK+V
Sbjct: 439 FTQNLDTAHRLMRALRVGTVWINCFDVLDASIPFGGYKMSGIGREKGIYSLNNYLQVKAV 498
Query: 496 HVNL 499
+L
Sbjct: 499 VTSL 502
>CE29393 [C] KOG2450 Aldehyde dehydrogenase
Length = 510
Score = 377 bits (969), Expect = e-104
Identities = 213/492 (43%), Positives = 299/492 (60%), Gaps = 16/492 (3%)
Query: 16 QPLGLFINNEYVEAHGSETLTSYNPSSGEEICKVQCADPKIDVDLAVKAARDAF---PGW 72
Q G+FINNE+V A +T + NP++G+ + +V D K DV++AVKAA++AF W
Sbjct: 28 QYTGIFINNEFVPAKSGKTFETINPANGKVLAQVAEGD-KTDVNIAVKAAQNAFRIGSEW 86
Query: 73 KATPAIEKRDLFYKLAGLLERDIDILSKIESLDTGKPIANNAKYDILEVVEVLKYYAGWI 132
+ A ++ L +LA L+ERD IL+ +ESLD GKP A D+ ++ L+
Sbjct: 87 RRMDASQRGVLLNRLADLMERDRVILASLESLDNGKPYAVAYNADLPLSIKTLRLLRRMA 146
Query: 133 DKAGGQSFAPSSEKLAYTLHQPLGVVGCIIPFNYPLAMMSWKW-TAIATGNTTVFKSADQ 191
DK G++ + YT H+P+GV G IIP+N+PL M +WK A+A GNT V K A+Q
Sbjct: 147 DKNHGKTIPIEGDYFTYTRHEPVGVCGQIIPWNFPLLMQAWKLGPALAMGNTVVMKVAEQ 206
Query: 192 TPLSILYFAKLVKEAGFPAGVFNVLSGTGASVGSAIVKHTGVDKIAFTGSTAVGQIIQQQ 251
TPLS L+ A L KEAGFP GV N++ G G + G AI H VDK+AFTGST VG+++ +
Sbjct: 207 TPLSALHVAALTKEAGFPDGVVNIIPGYGHTAGQAISSHMDVDKVAFTGSTEVGRLVMKA 266
Query: 252 SAV-NLKPITLECGGKSANMIFEDCDLEQAVKWSAWGIFNNMGQICSGTSRVFVQESIYE 310
+A N+K +TLE GGKS N+IF D DL +V + G+F N GQ C SR FV+ IY+
Sbjct: 267 AAESNVKKVTLELGGKSPNIIFADADLNDSVHQANHGLFFNQGQCCCAGSRTFVEGKIYD 326
Query: 311 EFVAQLADHVKKTYIVGAPSDDAVIVGPQVSKKQQERVLEYIKIGIEEGCKVPLGGLGAP 370
+FVA+ + +K ++G P D GPQV KQ E +L+YI G ++G ++ GG
Sbjct: 327 DFVARSKELAEKA-VIGDPFDLKTTQGPQVDGKQVETILKYIAAGKKDGAQLVTGGAKHG 385
Query: 371 EPIANDPALANGYYVKPTILADVKASYRIAKEEIFGPVIVVGSFKDYKEALDIANDSDYG 430
+ G++VKPTI A+VK IA+EEIFGPV+ + F +E ++ AN++ YG
Sbjct: 386 D---------QGHFVKPTIFANVKDQMTIAQEEIFGPVMTIIRFDTMEELVEKANNTIYG 436
Query: 431 LGSAIFSKDIVTCHKFAQDVEAGMVWINSSNDVDINVPFGGVKMSGHGRELGEYGLANFT 490
L + + +KDI A AG VW+N + D PFGG K SG GRELGEYGL +T
Sbjct: 437 LAAGVMTKDIDKALHIANATRAGSVWVNCYDVFDAAAPFGGFKQSGIGRELGEYGLEAYT 496
Query: 491 NVKSVHVNLGRK 502
VK+V + + +K
Sbjct: 497 EVKTVTIKVPQK 508
>YPL061w [C] KOG2450 Aldehyde dehydrogenase
Length = 500
Score = 375 bits (963), Expect = e-104
Identities = 207/498 (41%), Positives = 306/498 (60%), Gaps = 15/498 (3%)
Query: 6 IKLADGTEYQQPLGLFINNEYVEAHGSETLTSYNPSSGEEICKVQCADPKIDVDLAVKAA 65
I L +G Y+QP GLFINN++++A +T +PS+ +C+V A + DV+ A++ A
Sbjct: 14 ITLPNGLTYEQPTGLFINNKFMKAQDGKTYPVEDPSTENTVCEVSSATTE-DVEYAIECA 72
Query: 66 RDAFPG--WKATPAIEKRDLFYKLAGLLERDIDILSKIESLDTGKPIANNAKYDILEVVE 123
AF W E+ L KLA LE ID++S IE+LD GK +A A+ D+ +
Sbjct: 73 DRAFHDTEWATQDPRERGRLLSKLADELESQIDLVSSIEALDNGKTLAL-ARGDVTIAIN 131
Query: 124 VLKYYAGWIDKAGGQSFAPSSEKLAYTLHQPLGVVGCIIPFNYPLAMMSWKWT-AIATGN 182
L+ A + DK G++ + +T +P+GV G IIP+N+P+ M++WK A+A GN
Sbjct: 132 CLRDAAAYADKVNGRTINTGDGYMNFTTLEPIGVCGQIIPWNFPIMMLAWKIAPALAMGN 191
Query: 183 TTVFKSADQTPLSILYFAKLVKEAGFPAGVFNVLSGTGASVGSAIVKHTGVDKIAFTGST 242
+ K A TPL+ LYFA L K+ G PAGV N++ G G +VG+A+ + K+AFTGST
Sbjct: 192 VCILKPAAVTPLNALYFASLCKKVGIPAGVVNIVPGPGRTVGAALTNDPRIRKLAFTGST 251
Query: 243 AVGQIIQQQSAV-NLKPITLECGGKSANMIFEDCDLEQAVKWSAWGIFNNMGQICSGTSR 301
VG+ + S+ NLK ITLE GGKSA+++F+D ++++ + GIF N GQICS SR
Sbjct: 252 EVGKSVAVDSSESNLKKITLELGGKSAHLVFDDANIKKTLPNLVNGIFKNAGQICSSGSR 311
Query: 302 VFVQESIYEEFVAQLADHVKKTYIVGAPSDDAVIVGPQVSKKQQERVLEYIKIGIEEGCK 361
++VQE IY+E +A +++ VG P D A G +++Q + ++ YI IG +EG K
Sbjct: 312 IYVQEGIYDELLAAFKAYLETEIKVGNPFDKANFQGAITNRQQFDTIMNYIDIGKKEGAK 371
Query: 362 VPLGGLGAPEPIANDPALANGYYVKPTILADVKASYRIAKEEIFGPVIVVGSFKDYKEAL 421
+ GG E + + GY+++PT+ DV RI KEEIFGPV+ V FK +E +
Sbjct: 372 ILTGG----EKVGD-----KGYFIRPTVFYDVNEDMRIVKEEIFGPVVTVAKFKTLEEGV 422
Query: 422 DIANDSDYGLGSAIFSKDIVTCHKFAQDVEAGMVWINSSNDVDINVPFGGVKMSGHGREL 481
++AN S++GLGS I ++ + T K A+ ++AG VWIN+ ND D VPFGGVK SG+GRE+
Sbjct: 423 EMANSSEFGLGSGIETESLSTGLKVAKMLKAGTVWINTYNDFDSRVPFGGVKQSGYGREM 482
Query: 482 GEYGLANFTNVKSVHVNL 499
GE +T VK+V + L
Sbjct: 483 GEEVYHAYTEVKAVRIKL 500
>At3g48000 [C] KOG2450 Aldehyde dehydrogenase
Length = 538
Score = 368 bits (945), Expect = e-101
Identities = 198/486 (40%), Positives = 292/486 (59%), Gaps = 15/486 (3%)
Query: 20 LFINNEYVEAHGSETLTSYNPSSGEEICKVQCADPKIDVDLAVKAARDAFPG--WKATPA 77
L IN +V++ +T + +P +GE I V D + D++ AVKAAR AF W A
Sbjct: 60 LLINGNFVDSASGKTFPTLDPRTGEVIAHVAEGDAE-DINRAVKAARTAFDEGPWPKMSA 118
Query: 78 IEKRDLFYKLAGLLERDIDILSKIESLDTGKPIANNAKYDILEVVEVLKYYAGWIDKAGG 137
E+ + + A L+E+ + L+ +E+ D GKP + +I + +YYAGW DK G
Sbjct: 119 YERSRVLLRFADLVEKHSEELASLETWDNGKPYQQSLTAEIPMFARLFRYYAGWADKIHG 178
Query: 138 QSFAPSSEKLAYTLHQPLGVVGCIIPFNYPLAMMSWK-WTAIATGNTTVFKSADQTPLSI 196
+ +TLH+P+GV G IIP+N+PL M +WK A+A GNT V K+A+QTPL+
Sbjct: 179 LTIPADGNYQVHTLHEPIGVAGQIIPWNFPLLMFAWKVGPALACGNTIVLKTAEQTPLTA 238
Query: 197 LYFAKLVKEAGFPAGVFNVLSGTGASVGSAIVKHTGVDKIAFTGSTAVGQIIQQQSA-VN 255
Y KL EAG P GV N++SG GA+ G+A+ H VDK+AFTGST G++I +A N
Sbjct: 239 FYAGKLFLEAGLPPGVLNIVSGFGATAGAALASHMDVDKLAFTGSTDTGKVILGLAANSN 298
Query: 256 LKPITLECGGKSANMIFEDCDLEQAVKWSAWGIFNNMGQICSGTSRVFVQESIYEEFVAQ 315
LKP+TLE GGKS ++FED D+++AV+ + + +F N GQ C SR FV E +Y+EFV +
Sbjct: 299 LKPVTLELGGKSPFIVFEDADIDKAVELAHFALFFNQGQCCCAGSRTFVHEKVYDEFVEK 358
Query: 316 LADHVKKTYIVGAPSDDAVIVGPQVSKKQQERVLEYIKIGIEEGCKVPLGGLGAPEPIAN 375
K +VG P + GPQ+ KQ E+V++YIK GIE + GG
Sbjct: 359 SKARALKR-VVGDPFRKGIEQGPQIDLKQFEKVMKYIKSGIESNATLECGG--------- 408
Query: 376 DPALANGYYVKPTILADVKASYRIAKEEIFGPVIVVGSFKDYKEALDIANDSDYGLGSAI 435
D GY+++PT+ ++VK IA++EIFGPV + F D E + AN++ YGL + +
Sbjct: 409 DQIGDKGYFIQPTVFSNVKDDMLIAQDEIFGPVQSILKFSDVDEVIKRANETKYGLAAGV 468
Query: 436 FSKDIVTCHKFAQDVEAGMVWINSSNDVDINVPFGGVKMSGHGRELGEYGLANFTNVKSV 495
F+K++ T ++ ++ ++AG VW+N + D +PFGG KMSG+GRE G Y L N+ +K+V
Sbjct: 469 FTKNLDTANRVSRALKAGTVWVNCFDVFDAAIPFGGYKMSGNGREKGIYSLNNYLQIKAV 528
Query: 496 HVNLGR 501
L +
Sbjct: 529 VTALNK 534
>Hs18579349 [F] KOG2452 Formyltetrahydrofolate dehydrogenase
Length = 975
Score = 348 bits (892), Expect = 1e-95
Identities = 195/478 (40%), Positives = 283/478 (58%), Gaps = 21/478 (4%)
Query: 15 QQPLGLFINNEYVEAHGSETLTSYNPSSGEEICKVQCADPKIDVDLAVKAARDAFPG--W 72
+ P FIN ++ +A +T + NP+ G ICKV A DVD AV AA+DAF W
Sbjct: 440 KMPYQCFINGQFTDADDGKTYDTINPTDGSTICKVSYAS-LADVDKAVAAAKDAFENGEW 498
Query: 73 KATPAIEKRDLFYKLAGLLERDIDILSKIESLDTGKPIANNAKYDILEVVEVLKYYAGWI 132
A E+ L Y+LA LLE + + L+ IE+LD+G K I V+ +Y+AGW
Sbjct: 499 GRMNARERGRLMYRLADLLEENQEELATIEALDSGAVYTLALKTHIGMSVQTFRYFAGWC 558
Query: 133 DKAGGQSF----APSSEKLAYTLHQPLGVVGCIIPFNYPLAMMSWKWTA-IATGNTTVFK 187
DK G + A + L +T +PLGV IIP+NYPL M++WK A +A GNT V K
Sbjct: 559 DKIQGSTIPINQARPNRNLTFTKKEPLGVCAIIIPWNYPLMMLAWKSAACLAAGNTLVLK 618
Query: 188 SADQTPLSILYFAKLVKEAGFPAGVFNVLSGTGASVGSAIVKHTGVDKIAFTGSTAVGQI 247
A TPL+ L FA+L +AGFP GV N++ G+G G + +H + K+ FTGST +G+
Sbjct: 619 PAQVTPLTALKFAELSVKAGFPKGVINIIPGSGGIAGQRLSEHPDIRKLGFTGSTPIGKQ 678
Query: 248 IQQQSAV-NLKPITLECGGKSANMIFEDCDLEQAVKWSAWGIFNNMGQICSGTSRVFVQE 306
I + AV NLK ++LE GGKS +IF DC+L++AV+ +F N G+ C R+FV+E
Sbjct: 679 IMKSCAVSNLKKVSLELGGKSPLIIFNDCELDKAVRMGMGAVFFNKGENCIAAGRLFVEE 738
Query: 307 SIYEEFVAQLADHVKKTYIVGAPSDDAVIVGPQVSKKQQERVLEYIKIGIEEGCKVPLGG 366
SI++EFV ++ + +KK I G P D + GPQ K E++L+Y + G++EG + GG
Sbjct: 739 SIHDEFVTRVVEEIKKMKI-GDPLDRSTDHGPQNHKAHLEKLLQYCETGVKEGATLVYGG 797
Query: 367 LGAPEPIANDPALANGYYVKPTILADVKASYRIAKEEIFGPVIVVGSFK--DYKEALDIA 424
P G++++PT+ DV+ +AKEE FGP++V+ F+ D L A
Sbjct: 798 RQVQRP---------GFFMEPTVFTDVEDYMYLAKEESFGPIMVISKFQNGDIDGVLQRA 848
Query: 425 NDSDYGLGSAIFSKDIVTCHKFAQDVEAGMVWINSSNDVDINVPFGGVKMSGHGRELG 482
N ++YGL S +F++DI ++ +EAG V+IN+ N D+ PFGGVK SG G++LG
Sbjct: 849 NSTEYGLASGVFTRDINKAMYVSEKLEAGTVFINTYNKTDVAAPFGGVKQSGFGKDLG 906
>Hs21614513 [F] KOG2452 Formyltetrahydrofolate dehydrogenase
Length = 902
Score = 343 bits (881), Expect = 3e-94
Identities = 198/491 (40%), Positives = 285/491 (57%), Gaps = 21/491 (4%)
Query: 15 QQPLGLFINNEYVEAHGSETLTSYNPSSGEEICKVQCADPKIDVDLAVKAARDAFPG--W 72
+ P LFI E+V+A G++T + NP+ G IC+V A DVD AV AA+DAF W
Sbjct: 419 RMPHQLFIGGEFVDAEGAKTSETINPTDGSVICQVSLAQVT-DVDKAVAAAKDAFENGRW 477
Query: 73 KATPAIEKRDLFYKLAGLLERDIDILSKIESLDTGKPIANNAKYDILEVVEVLKYYAGWI 132
A ++ L Y+LA L+E+ + L+ IE+LD G K + ++ +Y+AGW
Sbjct: 478 GKISARDRGRLMYRLADLMEQHQEELATIEALDAGAVYTLALKTHVGMSIQTFRYFAGWC 537
Query: 133 DKAGGQSF----APSSEKLAYTLHQPLGVVGCIIPFNYPLAMMSWKWTA-IATGNTTVFK 187
DK G + A + L T +P+GV G IIP+NYPL M+SWK A +A GNT V K
Sbjct: 538 DKIQGSTIPINQARPNRNLTLTRKEPVGVCGIIIPWNYPLMMLSWKTAACLAAGNTVVIK 597
Query: 188 SADQTPLSILYFAKLVKEAGFPAGVFNVLSGTGASVGSAIVKHTGVDKIAFTGSTAVGQI 247
A TPL+ L FA+L +AG P GV NVL G+G+ VG + H V KI FTGST VG+
Sbjct: 598 PAQVTPLTALKFAELTLKAGIPKGVVNVLPGSGSLVGQRLSDHPDVRKIGFTGSTEVGKH 657
Query: 248 IQQQSAV-NLKPITLECGGKSANMIFEDCDLEQAVKWSAWGIFNNMGQICSGTSRVFVQE 306
I + A+ N+K ++LE GGKS +IF DCDL +AV+ +F N G+ C R+FV++
Sbjct: 658 IMKSCAISNVKKVSLELGGKSPLIIFADCDLNKAVQMGMSSVFFNKGENCIAAGRLFVED 717
Query: 307 SIYEEFVAQLADHVKKTYIVGAPSDDAVIVGPQVSKKQQERVLEYIKIGIEEGCKVPLGG 366
SI++EFV ++ + V+K VG P D GPQ +++EY + G++EG + GG
Sbjct: 718 SIHDEFVRRVVEEVRKMK-VGNPLDRDTDHGPQNHHAHLVKLMEYCQHGVKEGATLVCGG 776
Query: 367 LGAPEPIANDPALANGYYVKPTILADVKASYRIAKEEIFGPVIVVGSFK--DYKEALDIA 424
P P G++ +PT+ DV+ IAKEE FGPV+++ F D L A
Sbjct: 777 NQVPRP---------GFFFEPTVFTDVEDHMFIAKEESFGPVMIISRFADGDLDAVLSRA 827
Query: 425 NDSDYGLGSAIFSKDIVTCHKFAQDVEAGMVWINSSNDVDINVPFGGVKMSGHGRELGEY 484
N +++GL S +F++DI + ++AG V++N+ N D+ PFGG K SG G++LGE
Sbjct: 828 NATEFGLASGVFTRDINKALYVSDKLQAGTVFVNTYNKTDVAAPFGGFKQSGFGKDLGEA 887
Query: 485 GLANFTNVKSV 495
L + VK+V
Sbjct: 888 ALNEYLRVKTV 898
>HsM7110595 [F] KOG2452 Formyltetrahydrofolate dehydrogenase
Length = 902
Score = 337 bits (865), Expect = 2e-92
Identities = 195/491 (39%), Positives = 284/491 (57%), Gaps = 21/491 (4%)
Query: 15 QQPLGLFINNEYVEAHGSETLTSYNPSSGEEICKVQCADPKIDVDLAVKAARDAFPG--W 72
+ P LFI E+V+A G++T + NP+ G IC+V A DVD AV AA+ AF W
Sbjct: 419 RMPHQLFIGGEFVDAEGAKTSETINPTDGSVICQVSLAQVT-DVDKAVAAAKGAFENGRW 477
Query: 73 KATPAIEKRDLFYKLAGLLERDIDILSKIESLDTGKPIANNAKYDILEVVEVLKYYAGWI 132
A ++ L Y+LA L+E+ + L+ IE+LD G K + ++ +Y+AGW
Sbjct: 478 GKISARDRGRLMYRLADLMEQHQEELATIEALDAGAVYTLALKTHVGMSIQTFRYFAGWC 537
Query: 133 DKAGGQSF----APSSEKLAYTLHQPLGVVGCIIPFNYPLAMMSWKWTA-IATGNTTVFK 187
DK G + A + L T +P+GV G IIP+NYPL M+SWK A +A GNT V K
Sbjct: 538 DKIQGSTIPINQARPNRNLTLTRKEPVGVCGIIIPWNYPLMMLSWKTAACLAAGNTVVIK 597
Query: 188 SADQTPLSILYFAKLVKEAGFPAGVFNVLSGTGASVGSAIVKHTGVDKIAFTGSTAVGQI 247
A TPL+ L FA+L +AG P GV NVL G+G+ VG + H V KI FTGST VG+
Sbjct: 598 PAQVTPLTALKFAELTLKAGIPKGVVNVLPGSGSLVGQRLSDHPDVRKIGFTGSTEVGKH 657
Query: 248 IQQQSAV-NLKPITLECGGKSANMIFEDCDLEQAVKWSAWGIFNNMGQICSGTSRVFVQE 306
I + A+ N+K ++LE GG+S +IF DCDL +AV+ +F + G+ C R+FV++
Sbjct: 658 IMKSCAISNVKKVSLELGGESPFIIFADCDLNKAVQMGMSSVFFSKGENCIAAGRLFVED 717
Query: 307 SIYEEFVAQLADHVKKTYIVGAPSDDAVIVGPQVSKKQQERVLEYIKIGIEEGCKVPLGG 366
SI++EFV ++ + V+K VG P D GPQ +++EY + G++EG + GG
Sbjct: 718 SIHDEFVRRVVEEVRKMK-VGNPLDRDTDHGPQNHHAHLVKLMEYCQHGVKEGATLVCGG 776
Query: 367 LGAPEPIANDPALANGYYVKPTILADVKASYRIAKEEIFGPVIVVGSFK--DYKEALDIA 424
P P G++ +PT+ DV+ IAKEE FGPV+++ F D L A
Sbjct: 777 NQVPRP---------GFFFEPTVFTDVEDHMFIAKEESFGPVMIISRFADGDLDAVLSRA 827
Query: 425 NDSDYGLGSAIFSKDIVTCHKFAQDVEAGMVWINSSNDVDINVPFGGVKMSGHGRELGEY 484
N +++GL S +F++DI + ++AG V++N+ N D+ PFGG K SG G++LGE
Sbjct: 828 NATEFGLASGVFTRDINKALYVSDKLQAGTVFVNTYNKTDVAAPFGGFKQSGFGKDLGEA 887
Query: 485 GLANFTNVKSV 495
L + VK+V
Sbjct: 888 ALNEYLRVKTV 898
>At3g48170 [C] KOG2450 Aldehyde dehydrogenase
Length = 503
Score = 325 bits (832), Expect = 1e-88
Identities = 191/487 (39%), Positives = 282/487 (57%), Gaps = 22/487 (4%)
Query: 20 LFINNEYVEAHGSETLTSYNPSSGEEICKVQCADPKIDVDLAVKAARDAFP-----GW-K 73
LFI ++ E +TL NP++ + I + A + DV+LAV+AAR AF W +
Sbjct: 10 LFIGGQWTEPVLRKTLPVVNPATEDIIGYIPAATSE-DVELAVEAARKAFTRNNGKDWAR 68
Query: 74 ATPAIEKRDLFYKLAGLLERDIDILSKIESLDTGKPIANNAKYDILEVVEVLKYYAGWID 133
AT A+ + L A ++ER + L+ +E++D GKP+ + A +D+ +V +YYA +
Sbjct: 69 ATGAVRAKYLRAIAAKVIERKSE-LANLEAIDCGKPL-DEAAWDMDDVAGCFEYYADLAE 126
Query: 134 KAGGQSFAPSSEKL----AYTLHQPLGVVGCIIPFNYPLAMMSWKWT-AIATGNTTVFKS 188
+ P S + Y L +P+GVVG I P+NYPL M WK ++A G T + K
Sbjct: 127 GLDAKQKTPLSLPMDTFKGYILKEPIGVVGMITPWNYPLLMAVWKVAPSLAAGCTAILKP 186
Query: 189 ADQTPLSILYFAKLVKEAGFPAGVFNVLSGTGASVGSAIVKHTGVDKIAFTGSTAVGQII 248
++ L+ L A + +E G P GV N+L+G G G+ + H VDKI FTGST G I
Sbjct: 187 SELASLTCLELADICREVGLPPGVLNILTGLGTEAGAPLASHPHVDKIVFTGSTTTGSSI 246
Query: 249 QQQSAVNLKPITLECGGKSANMIFEDCDLEQAVKWSAWGIFNNMGQICSGTSRVFVQESI 308
+A +KP++LE GGKS ++F+D D+++AV+W+ +G F GQICS TSR+ V E I
Sbjct: 247 MTSAAKLVKPVSLELGGKSPIIVFDDVDIDKAVEWTMFGCFWTNGQICSATSRLLVHERI 306
Query: 309 YEEFVAQLADHVKKTYIVGAPSDDAVIVGPQVSKKQQERVLEYIKIGIEEGCKVPLGGLG 368
+EF+ +L K I P ++ +GP VSK Q ERVL+++ EG V GG+
Sbjct: 307 ADEFLDKLVKWTKNIKI-SDPFEEGCRLGPVVSKGQYERVLKFVSNARNEGATVLCGGV- 364
Query: 369 APEPIANDPALANGYYVKPTILADVKASYRIAKEEIFGPVIVVGSFKDYKEALDIANDSD 428
PE L GY+V+P I+++V S I +EE+FGP + V +F EA+ +ANDS
Sbjct: 365 RPE------HLKKGYFVEPAIVSNVTTSMEIWREEVFGPALCVKTFSTEDEAIQLANDSQ 418
Query: 429 YGLGSAIFSKDIVTCHKFAQDVEAGMVWINSSNDVDINVPFGGVKMSGHGRELGEYGLAN 488
YGL A+ S D+ C + ++ +AG+VW+N S P+GG K SG GRELGE+GL N
Sbjct: 419 YGLAGAVLSNDLERCDRVSKAFQAGIVWVNCSQPCFCQAPWGGTKRSGFGRELGEWGLEN 478
Query: 489 FTNVKSV 495
+ +VK V
Sbjct: 479 YLSVKQV 485
>At1g74920 [C] KOG2450 Aldehyde dehydrogenase
Length = 481
Score = 308 bits (788), Expect = 2e-83
Identities = 190/493 (38%), Positives = 274/493 (55%), Gaps = 54/493 (10%)
Query: 20 LFINNEYVEAHGSETLTSYNPSSGE------EICKVQCADPKIDVDLAVKAARDAFP--- 70
LFI+ E+ E + + NP++ E EI + A + DVD+AV AAR A
Sbjct: 10 LFIDGEWREPILKKRIPIVNPATEEDLYVLDEIGDIPAATTE-DVDVAVNAARRALSRNK 68
Query: 71 --GW-KATPAIEKRDLFYKLAGLLERDIDILSKIESLDTGKPIANNAKYDILEVVEVLKY 127
W KA A+ + L A + ER D L+K+E+LD GKP+ + A +D+ +V ++
Sbjct: 69 GKDWAKAPGAVRAKYLRAIAAKVNERKTD-LAKLEALDCGKPL-DEAVWDMDDVAGCFEF 126
Query: 128 YAGWIDKAGGQSFAPSSEKL----AYTLHQPLGVVGCIIPFNYPLAMMSWKWT-AIATGN 182
YA + + AP S + +Y L QPLGVVG I P+NYPL M WK ++A G
Sbjct: 127 YADLAEGLDAKQKAPVSLPMESFKSYVLKQPLGVVGLITPWNYPLLMAVWKVAPSLAAGC 186
Query: 183 TTVFKSADQTPLSILYFAKLVKEAGFPAGVFNVLSGTGASVGSAIVKHTGVDKIAFTGST 242
T + K ++ ++ L A + +E G P GV NVL+G G+ G+ + H GVDKIAFTGS
Sbjct: 187 TAILKPSELASVTCLELADICREVGLPPGVLNVLTGFGSEAGAPLASHPGVDKIAFTGSF 246
Query: 243 AVGQIIQQQSAVNLKPITLECGGKSANMIFEDCDLEQAVKWSAWGIFNNMGQICSGTSRV 302
A G + +A +KP+++E GGKS ++F+D DL++A +W+ +G F GQICS TSR+
Sbjct: 247 ATGSKVMTAAAQLVKPVSMELGGKSPLIVFDDVDLDKAAEWALFGCFWTNGQICSATSRL 306
Query: 303 FVQESIYEEFVAQLADHVKKTYIVGAPSDDAVIVGPQVSKKQQERVLEYIKIGIEEGCKV 362
V ESI EF+ +L K + P ++ +GP VSK Q
Sbjct: 307 LVHESIASEFIEKLVKW-SKNIKISDPMEEGCRLGPVVSKGQH----------------- 348
Query: 363 PLGGLGAPEPIANDPALANGYYVKPTILADVKASYRIAKEEIFGPVIVVGSFKDYKEALD 422
L G++++PTI+ DV S +I +EE+FGPV+ V +F EA++
Sbjct: 349 ----------------LEKGFFIEPTIITDVTTSMQIWREEVFGPVLCVKTFASEDEAIE 392
Query: 423 IANDSDYGLGSAIFSKDIVTCHKFAQDVEAGMVWINSSNDVDINVPFGGVKMSGHGRELG 482
+ANDS YGLG+A+ S D C + ++ EAG+VWIN S P+GGVK SG GRELG
Sbjct: 393 LANDSHYGLGAAVISNDTERCDRISEAFEAGIVWINCSQPCFTQAPWGGVKRSGFGRELG 452
Query: 483 EYGLANFTNVKSV 495
E+GL N+ +VK V
Sbjct: 453 EWGLDNYLSVKQV 465
>Hs4502047 [C] KOG2450 Aldehyde dehydrogenase
Length = 493
Score = 303 bits (777), Expect = 3e-82
Identities = 174/471 (36%), Positives = 267/471 (55%), Gaps = 10/471 (2%)
Query: 32 SETLTSYNPSSGEEICKVQCADPKIDVDLAVKAARDAFPGWKATPAIEKRDLFYKLAGLL 91
S T ++ P++G I C+ K +V+LAV+ A+ AF W +E+ + + A ++
Sbjct: 25 SGTEKAFEPATGRVIATFTCSGEK-EVNLAVQNAKAAFKIWSQKSGMERCRILLEAARII 83
Query: 92 ERDIDILSKIESLDTGKPIANNAKYDILEVVEVLKYYAGWIDKAGGQSFAPSSEKLAYTL 151
D ++ +E ++ GK I A+ DI + L+YYAG G+ YT
Sbjct: 84 REREDEIATMECINNGKSIFE-ARLDIDISWQCLEYYAGLAASMAGEHIQLPGGSFGYTR 142
Query: 152 HQPLGVVGCIIPFNYPLAMMSWKWT-AIATGNTTVFKSADQTPLSILYFAKLVKEAGFPA 210
+PLGV I +NYP + SWK A+A GN VFK + TP+S L A++ EAG P
Sbjct: 143 REPLGVCVGIGAWNYPFQIASWKSAPALACGNAMVFKPSPFTPVSALLLAEIYSEAGVPP 202
Query: 211 GVFNVLSGTGASVGSAIVKHTGVDKIAFTGSTAVGQIIQQQSAVNLKPITLECGGKSANM 270
G+FNV+ G GA+ G + +H V K++FTGS G I + SA +KP+TLE GGKS +
Sbjct: 203 GLFNVVQG-GAATGQFLCQHPDVAKVSFTGSVPTGMKIMEMSAKGIKPVTLELGGKSPLI 261
Query: 271 IFEDCDLEQAVKWSAWGIFNNMGQICSGTSRVFVQESIYEEFVAQLADHVKKTYIVGAPS 330
IF DCD+ AVK + F GQ+C +RVFVQ+ I ++F ++ ++ I G P
Sbjct: 262 IFSDCDMNNAVKGALMANFLTQGQVCCNGTRVFVQKEILDKFTEEVVKQTQRIKI-GDPL 320
Query: 331 DDAVIVGPQVSKKQQERVLEYIKIGIEEGCKVPLGG-LGAPEPIANDPALANGYYVKPTI 389
+ +GP +++ ERVL ++K+ E+G KV GG + PE DP L +GYY++P +
Sbjct: 321 LEDTRMGPLINRPHLERVLGFVKVAKEQGAKVLCGGDIYVPE----DPKLKDGYYMRPCV 376
Query: 390 LADVKASYRIAKEEIFGPVIVVGSFKDYKEALDIANDSDYGLGSAIFSKDIVTCHKFAQD 449
L + + KEEIFGPV+ + SF E L+ AND+ +GL + +F++DI H+ +
Sbjct: 377 LTNCRDDMTCVKEEIFGPVMSILSFDTEAEVLERANDTTFGLAAGVFTRDIQRAHRVVAE 436
Query: 450 VEAGMVWINSSNDVDINVPFGGVKMSGHGRELGEYGLANFTNVKSVHVNLG 500
++AG +IN+ N + +PFGG K SG GRE G + ++ +K+V V +G
Sbjct: 437 LQAGTCFINNYNVSPVELPFGGYKKSGFGRENGRVTIEYYSQLKTVCVEMG 487
>Hs12007648 [C] KOG2450 Aldehyde dehydrogenase
Length = 487
Score = 299 bits (765), Expect = 7e-81
Identities = 178/492 (36%), Positives = 281/492 (56%), Gaps = 14/492 (2%)
Query: 11 GTEYQQPLGLFINNEYVEAHGSETLTSYNPSSGEEICKVQCADPKIDVDLAVKAARDAFP 70
GT L FI+ +++ S + SY+PS+GE C+V + K +++ AVKAAR+AFP
Sbjct: 3 GTNALLMLENFIDGKFLPC--SSYIDSYDPSTGEVYCRVPNSG-KDEIEAAVKAAREAFP 59
Query: 71 GWKATPAIEKRDLFYKLAGLLERDIDILSKIESLDTGKPIANNAKYDILEVVEVLKYYAG 130
W + E+ + ++A LLE+ ++ ++ ES D GK +A DI V+ +++A
Sbjct: 60 SWSSRSPQERSRVLNQVADLLEQSLEEFAQAESKDQGKTLALARTMDIPRSVQNFRFFAS 119
Query: 131 WIDKAGGQSFAPSSEKLA---YTLHQPLGVVGCIIPFNYPLAMMSWKWT-AIATGNTTVF 186
S + L YT+ P+GV G I P+N PL +++WK A+A GNT +
Sbjct: 120 --SSLHHTSECTQMDHLGCMHYTVRAPVGVAGLISPWNLPLYLLTWKIAPAMAAGNTVIA 177
Query: 187 KSADQTPLSILYFAKLVKEAGFPAGVFNVLSGTGASVGSAIVKHTGVDKIAFTGSTAVGQ 246
K ++ T ++ KL+ +AG P GV N++ GTG VG A+V H V I+FTGS +
Sbjct: 178 KPSELTSVTAWMLCKLLDKAGVPPGVVNIVFGTGPRVGEALVSHPEVPLISFTGSQPTAE 237
Query: 247 IIQQQSAVNLKPITLECGGKSANMIFEDCDLEQAVKWSAWGIFNNMGQICSGTSRVFVQE 306
I Q SA + K ++LE GGK+ +IFED +L++ + + F N G+IC TSR+FVQ+
Sbjct: 238 RITQLSAPHCKKLSLELGGKNPAIIFEDANLDECIPATVRSSFANQGEICLCTSRIFVQK 297
Query: 307 SIYEEFVAQLADHVKKTYIVGAPSDDAVIVGPQVSKKQQERVLEYIKIGIEEGCKVPLG- 365
SIY EF+ + + +K + VG PSD V +G +SK E+V Y+K + EG ++ G
Sbjct: 298 SIYSEFLKRFVEATRK-WKVGIPSDPLVSIGALISKAHLEKVRSYVKRALAEGAQIWCGE 356
Query: 366 GLGAPEPIANDPALANGYYVKPTILADVKASYRIAKEEIFGPVIVVGSFKDYKEALDIAN 425
G+ A + A GY++ PT++ D+K EEIFGPV V F +E ++ AN
Sbjct: 357 GVDKLSLPARNQA---GYFMLPTVITDIKDESCCMTEEIFGPVTCVVPFDSEEEVIERAN 413
Query: 426 DSDYGLGSAIFSKDIVTCHKFAQDVEAGMVWINSSNDVDINVPFGGVKMSGHGRELGEYG 485
+ YGL + ++S ++ H+ A+ +++G+VW N ++N+PFGG+K SG GRE +
Sbjct: 414 NVKYGLAATVWSSNVGRVHRVAKKLQSGLVWTNCWLIRELNLPFGGMKSSGIGREGAKDS 473
Query: 486 LANFTNVKSVHV 497
FT +K++ V
Sbjct: 474 YDFFTEIKTITV 485
>CE07233 [C] KOG2450 Aldehyde dehydrogenase
Length = 687
Score = 298 bits (763), Expect = 1e-80
Identities = 176/482 (36%), Positives = 267/482 (54%), Gaps = 11/482 (2%)
Query: 21 FINNEYVEAHGSETLTSYNPSSGEEICKVQCADPKIDVDLAVKAARDAFPGWKATPAIEK 80
F+ +VE P SG+ + A + VDL VK A+ A W + +E+
Sbjct: 209 FVAGNHVEFPSDRKFEVIEPRSGKPMATWHYAT-RDQVDLTVKEAKKAQKQWAKSSWMER 267
Query: 81 RDLFYKLAGLLERDIDILSKIESLDTGKPIANNAKYDILEVVEVLKYYAGWIDKAGGQSF 140
++ K LL+ + ++ E + GKPIA AK D+L V+ +Y+G GQ
Sbjct: 268 SEILKKTGDLLKTHCNDIAYWECISNGKPIAE-AKADVLSCVDTFYFYSGIASDLLGQHV 326
Query: 141 APSSEKLAYTLHQPLGVVGCIIPFNYPLAMMSWKWT-AIATGNTTVFKSADQTPLSILYF 199
+ + AYT P+GVV I +NYP+ SWK A+A GN ++K + +P++ L
Sbjct: 327 PLDASRYAYTRRLPVGVVAAIGAWNYPIQTCSWKTAPALACGNAVIYKPSPLSPVTALIL 386
Query: 200 AKLVKEAGFPAGVFNVLSGTGASVGSAIVKHTGVDKIAFTGSTAVGQIIQQQSAV-NLKP 258
A+++K AG P GVFNV+ G A ++ H GV K++FTGS G+ I + A N+KP
Sbjct: 387 AEILKSAGLPDGVFNVIQGD-AETAQDLIHHDGVSKVSFTGSIPTGKKIMKACADRNIKP 445
Query: 259 ITLECGGKSANMIFEDCDLEQAVKWSAWGIFNNMGQICSGTSRVFVQESIYEEFVAQLAD 318
+TLE GGKSA ++F+D D++ AV + F + GQ+CS S+V V +S+ +EF +L D
Sbjct: 446 VTLELGGKSALIVFDDADIDSAVSCAMMANFYSQGQVCSNASKVLVHKSVLKEFTKKLVD 505
Query: 319 HVKKTYIVGAPSDDAVIVGPQVSKKQQERVLEYIKIGIEEGCKVPLGGLGAPEPIANDPA 378
H +K I G P + VG +S + + +V YI I EG GG + +A
Sbjct: 506 HTQKMKI-GDPLKEDTQVGSHISAEHRNKVEGYISTAIAEGATKLCGG----DRVAVH-G 559
Query: 379 LANGYYVKPTILADVKASYRIAKEEIFGPVIVVGSFKDYKEALDIANDSDYGLGSAIFSK 438
L NG+Y+ P IL + + +EEIFG V+++ F EA+ IAND+D GL + + +K
Sbjct: 560 LENGFYLSPCILTGITPKMTVYREEIFGSVLLIIPFDTEDEAIKIANDTDMGLAAGLVTK 619
Query: 439 DIVTCHKFAQDVEAGMVWINSSNDVDINVPFGGVKMSGHGRELGEYGLANFTNVKSVHVN 498
D+ ++ ++ + AG V++N+ NDV VPFGGV SG GRE G L ++T++KSV VN
Sbjct: 620 DLSRSYRVSEQLNAGNVYVNTYNDVSPLVPFGGVGESGFGRENGTAVLEHYTHLKSVFVN 679
Query: 499 LG 500
G
Sbjct: 680 TG 681
>SPCC550.10 [C] KOG2450 Aldehyde dehydrogenase
Length = 500
Score = 287 bits (735), Expect = 2e-77
Identities = 179/489 (36%), Positives = 271/489 (54%), Gaps = 19/489 (3%)
Query: 20 LFINNEYVEA--HGSETLTSYNPSSGEEICKVQCADPKIDVDLAVKAARDAFPG--WKAT 75
LFI+ ++V ++ + NP++ E I A K DVD AV+ A + F W
Sbjct: 23 LFIDGKFVSPIEPAAKPIPLINPATEEIIGTCANASAK-DVDSAVENAYNTFRSGIWAKW 81
Query: 76 PAIEKRDLFYKLAGLLERDIDILSKIESLDTGKPIANNAKYDILEVVEVLKYYAGWIDKA 135
P ++ + K+A ++ ++L+ I++++ GKP A +DI ++ +YYA +
Sbjct: 82 PGKQRGLVLRKIAKMMREKRELLAGIDTINCGKPTPY-ALFDIDSCADMFEYYAEVAETD 140
Query: 136 GGQSFAPSSEK---LAYTLHQPLGVVGCIIPFNYPLAMMSWKWT-AIATGNTTVFKSADQ 191
P A+ P GV+G I P+N+PL M WK AIA+GN V K ++
Sbjct: 141 NPTVKVPLPNNPGFCAFEKRFPRGVIGVITPWNFPLKMALWKLVPAIASGNCVVLKPSEL 200
Query: 192 TPLSILYFAKLVKEAGFPAGVFNVLSGTGASVGSAIVKHTGVDKIAFTGSTAVGQIIQQQ 251
P S L FA + KEAG P GV NV+ G+G G+A+ H + +AFTGS A G+ I
Sbjct: 201 APWSCLEFALICKEAGLPDGVLNVIIGSGKESGAALSCHPKIAYLAFTGSLATGKKIMHA 260
Query: 252 SAVNLKPITLECGGKSANMIFEDCDLEQAVKWSAWGIFNNMGQICSGTSRVFVQESIYEE 311
+A N+ P+TLE GGKS +I ED DL A+ +A+ IF N G+ C+ SR+ V ES+ +E
Sbjct: 261 AAENIVPLTLELGGKSPLIICEDADLSLAIPSAAFAIFFNQGEACTAASRLIVHESVADE 320
Query: 312 FVAQLADHVKKTYIVGAPSDDAVIVGPQVSKKQQERVLEYIKIGIEEGCKVPLGGLGAPE 371
+ L K I+G D V +GP VSK Q E+++ YI+ I EGCK +GGL E
Sbjct: 321 VLGGLVSEANK-LIIGNGLDPQVTLGPVVSKTQFEKIVSYIQSAINEGCKCVVGGLPRSE 379
Query: 372 PIANDPALANGYYVKPTILADVKASYRIAKEEIFGPVIVVGSFKDYKEALDIANDSDYGL 431
GY++ PT+ +V+ +I +EEIFGPV+ V +F +EAL++ANDS+YGL
Sbjct: 380 --------QKGYFIPPTVFTNVQTHNKIWREEIFGPVLAVKTFHTNEEALELANDSEYGL 431
Query: 432 GSAIFSKDIVTCHKFAQDVEAGMVWINSSNDVDINVPFGGVKMSGHGRELGEYGLANFTN 491
GS +FS + T F+ ++EAGM +N+ + V +P+ G K SG G L ++G +
Sbjct: 432 GSGVFSTNPKTLEFFSNNIEAGMCSLNNYHVVTHELPWIGWKHSGLGVGLSKHGYNEYMR 491
Query: 492 VKSVHVNLG 500
+K + +G
Sbjct: 492 LKQITQYVG 500
>CE05817 [F] KOG2452 Formyltetrahydrofolate dehydrogenase
Length = 887
Score = 283 bits (723), Expect = 6e-76
Identities = 170/494 (34%), Positives = 268/494 (53%), Gaps = 40/494 (8%)
Query: 13 EYQQPLGLFINNEYVEAHGSETLTSYNPSSGEEICKVQCADPKIDVDLAVKAARDAFPG- 71
E + P FI+ ++V + T + NP++ + IC++ A DVD AV+AA+ AF
Sbjct: 423 ELKFPHDQFIDGKFVGSSDGRTFKTINPATEKPICELPLATVA-DVDRAVRAAKKAFERG 481
Query: 72 -WKATPAIEKRDLFYKLAGLLERDIDILSKIESLDTGKPIANNAKYDILEVVEVLKYYAG 130
W+ A E+ YKLA L+E + L+ +ESLD G K + ++V +Y+AG
Sbjct: 482 EWRQMSARERGKRLYKLAELMEEHKEELATLESLDAGAVYTLALKTHVGMSIDVWRYFAG 541
Query: 131 WIDKAGGQSF----APSSEKLAYTLHQPLGVVGCIIPFNYPLAMMSWKWTAIATGNTTVF 186
W DK G++ A ++ L TL +P+GVVG I P+NYPL M+SWK A
Sbjct: 542 WCDKIQGKTIPISNARPNKNLCLTLREPIGVVGLITPWNYPLMMLSWKMAACLAAAKI-- 599
Query: 187 KSADQTPLSILYFAKLVKEAGFPAGVFNVLSGTGASVGSAIVKHTGVDKIAFTGSTAVGQ 246
KL++ +G V N+++G+G+ VG+ + H V KI FTGST +G
Sbjct: 600 --------------KLIEISG----VINIVTGSGSLVGNRLTAHPDVRKIGFTGSTEIGA 641
Query: 247 IIQQQSAV-NLKPITLECGGKSANMIFEDCDLEQAVKWSAWGIFNNMGQICSGTSRVFVQ 305
+ + A N+K ++LE GGKS +IF D DLE+AVK + +F N G+ C RVF+
Sbjct: 642 TVMESCAKSNIKKVSLELGGKSPLIIFADADLEKAVKQACGAVFFNKGENCIAAGRVFIA 701
Query: 306 ESIYEEFVAQLADHVKKTYIVGAPSDDAVIVGPQVSKKQQERVLEYIKIGIEEGCKVPLG 365
+SI+++FV +L + K+ Y +G P D + GPQ +++EY++ + G KV +G
Sbjct: 702 KSIHDDFVKKLVEEAKQ-YQIGDPLDRSTAHGPQNHLAHLNKLVEYVEKAVAGGAKVEVG 760
Query: 366 GLGAPEPIANDPALANGYYVKPTILADVKASYRIAKEEIFGPVIVVGSF--KDYKEALDI 423
G G Y PTIL+++ A EE FGP++ V SF D ++ L
Sbjct: 761 GKRLER---------EGLYFPPTILSNIDDENFAASEESFGPIMCVSSFDDDDIEDVLRR 811
Query: 424 ANDSDYGLGSAIFSKDIVTCHKFAQDVEAGMVWINSSNDVDINVPFGGVKMSGHGRELGE 483
AND+++GL + +F++D + A+ + AG V++N+ D+ PFGG K SG G+++GE
Sbjct: 812 ANDTEFGLAAGVFTRDSSKSLRVAEALHAGTVFVNTYQKTDVAAPFGGFKQSGFGKDMGE 871
Query: 484 YGLANFTNVKSVHV 497
L + K++ +
Sbjct: 872 EALNEYLVTKTITI 885
>CE24573 [C] KOG2450 Aldehyde dehydrogenase
Length = 574
Score = 278 bits (710), Expect = 2e-74
Identities = 168/485 (34%), Positives = 260/485 (52%), Gaps = 14/485 (2%)
Query: 21 FINNEYVEAHGSETLTSYNPSSGEEICKVQCADPKIDVDLAVKAARDAFPGWKATPAIEK 80
F+N + +ET P G+ + K A I VD VKAA DA W T A+++
Sbjct: 90 FLNGKRTTIESTETFDVIEPRIGQVVAKCPKATADI-VDQYVKAAADAQSAWGETTALDR 148
Query: 81 RDLFYKLAGLLERDIDILSKIESLDTGKPIANNAKYDILEVVEVLKYYAGWIDKA--GGQ 138
+ +K+A L+ + ++ E GKPI A+ DI + ++ G G
Sbjct: 149 GKVLHKVADLIREHAEEIAIWEVKTNGKPIYE-ARCDIASSADTFDFFGGIATAVLQGDS 207
Query: 139 SFAPS--SEKLAYTLHQPLGVVGCIIPFNYPLAMMSWKWT-AIATGNTTVFKSADQTPLS 195
P S+++AYT +P GVVGCI +NYP WK A+A GN V+K + P S
Sbjct: 208 LELPGGPSQRIAYTRREPYGVVGCIGAWNYPFQTCVWKVAPALAAGNAVVYKPSPFAPAS 267
Query: 196 ILYFAKLVKEAGFPAGVFNVLSGTGASVGSAIVKHTGVDKIAFTGSTAVGQIIQQQSAV- 254
+ +++ AG P GV+NV+ G G A+ +H V K++FTGS A G+ +Q+Q+A
Sbjct: 268 PVLLGEILTAAGVPKGVYNVIQGE-QEAGVALCEHNLVAKVSFTGSVASGEAVQRQAATK 326
Query: 255 NLKPITLECGGKSANMIFEDCDLEQAVKWSAWGIFNNMGQICSGTSRVFVQESIYEEFVA 314
N+KP+TLE GGKS +IF+D D++ AV + F N GQ+C+ +RVFVQ+ I F
Sbjct: 327 NVKPVTLELGGKSEIIIFDDSDVKSAVASAMLANFLNQGQVCTNATRVFVQKGILASFTE 386
Query: 315 QLADHVKKTYIVGAPSDDAVIVGPQVSKKQQERVLEYIKIGIEEGCKVPLGGLGAPEPIA 374
+ VG P + VG +++ +R+L Y++ +EG V GG+
Sbjct: 387 AIVQEANDKLKVGDPLLEDTRVGANINEGHLQRILGYVESAKQEGGVVLRGGVRV----- 441
Query: 375 NDPALANGYYVKPTILADVKASYRIAKEEIFGPVIVVGSFKDYKEALDIANDSDYGLGSA 434
+ + G Y +P I+ + R +EEIFG V+++ F+ +E + AN++ YGL +
Sbjct: 442 HPTGVEGGAYFEPAIITGLSDEARAVREEIFGAVMLILPFETEEEVIARANNTTYGLAAG 501
Query: 435 IFSKDIVTCHKFAQDVEAGMVWINSSNDVDINVPFGGVKMSGHGRELGEYGLANFTNVKS 494
+FS ++ H+ A ++AG V+IN+ ND ++NVPFGG K SGHGRE L T K+
Sbjct: 502 VFSGNLARGHRVAARLQAGTVFINTYNDTEVNVPFGGFKNSGHGRENCIDTLRAHTQTKA 561
Query: 495 VHVNL 499
++VN+
Sbjct: 562 IYVNV 566
>SPAC139.05 [C] KOG2451 Aldehyde dehydrogenase
Length = 493
Score = 268 bits (686), Expect = 1e-71
Identities = 164/483 (33%), Positives = 277/483 (56%), Gaps = 19/483 (3%)
Query: 21 FINNEYVEAHGSETLTSYNPSSGEEICKVQCADPKID-VDLAVKAARDAFPGWKATPAIE 79
F+ +++ + ++T NP++GE I KV AD ++ A+ AA +AF +K ++
Sbjct: 21 FVQGKWISSPNNKTFEVDNPATGEIIGKV--ADVSVEETKKAISAANEAFKTYKNFTHVQ 78
Query: 80 KRDLFYKLAGLLERDIDILSKIESLDTGKPIANNAKYDILEVVEVLKYYAGWIDKAGGQS 139
+ L + A L+ + D L K+ +L+ GKP++ A+ ++ LK+YA + G
Sbjct: 79 RSQLLERWAELIMENKDDLVKMLTLENGKPLSQ-AEMEVTTCSGYLKWYAAEAVRTFGD- 136
Query: 140 FAPSS---EKLAYTLHQPLGVVGCIIPFNYPLAMMSWKW-TAIATGNTTVFKSADQTPLS 195
APSS + ++ QP+GV I P+N+P AM++ K A+A G T +F A +TP
Sbjct: 137 VAPSSLQSQNFLISIKQPVGVSALITPWNFPAAMIARKGGAALAAGCTAIFLPAFRTPYV 196
Query: 196 ILYFAKLVKEAGFPAGVFNVLSGTGASV-GSAIVKHTGVDKIAFTGSTAVGQIIQQQSAV 254
L +L +EAGFP GV NV++ + AS G + + V K++FTGST VG+I+ QSA
Sbjct: 197 CLGLVRLAQEAGFPDGVLNVITSSDASAHGKELTTNPIVRKVSFTGSTNVGKILMGQSAS 256
Query: 255 NLKPITLECGGKSANMIFEDCDLEQAVKWSAWGIFNNMGQICSGTSRVFVQESIYEEFVA 314
+K +++E GG + ++F D ++QAV+ FN+ GQ+C +RV+V +++Y+EFV+
Sbjct: 257 TIKKVSMELGGNAPFIVFPDFPIDQAVESFCTIKFNSCGQVCVCPNRVYVHKNVYDEFVS 316
Query: 315 QLADHVKKTYIVGAPSDDAVIVGPQVSKKQQERVLEYIKIGIEEGCKVPLGGLGAPEPIA 374
+L + VK T VG D + VGP +S+ ++V ++I+ + +G K+ +GG
Sbjct: 317 KLTEKVK-TIKVGDGFDSSSAVGPLISQDGCKKVSKHIEDAVSKGAKITVGG-------- 367
Query: 375 NDPALANGYYVKPTILADVKASYRIAKEEIFGPVIVVGSFKDYKEALDIANDSDYGLGSA 434
+ + + GY+ +PT+L+ V +A EE FGP+ V F D +E ++ ANDSD GL
Sbjct: 368 KEISSSKGYFFEPTVLSGVTQDMLVASEETFGPLASVFKFDDTEEVIEWANDSDVGLAGY 427
Query: 435 IFSKDIVTCHKFAQDVEAGMVWINSSNDVDINVPFGGVKMSGHGRELGEYGLANFTNVKS 494
+F+ ++ T A+++E G+V N + + FGG+K SG G+E G G+ F VK
Sbjct: 428 VFTNNLSTMIHVAKELEVGLVGANIEMVDEPFISFGGIKQSGFGKEAGRLGVQEFMVVKE 487
Query: 495 VHV 497
+++
Sbjct: 488 INL 490
>CE06980 [C] KOG2450 Aldehyde dehydrogenase
Length = 506
Score = 268 bits (685), Expect = 1e-71
Identities = 173/501 (34%), Positives = 270/501 (53%), Gaps = 16/501 (3%)
Query: 7 KLADG-TEYQQPLGLFINNEYVEAHGSETLTSYNPSSGEEICKVQCADPKIDVDLAVKAA 65
KL D E PL FI NE+ A + + S NPS+G+ K+ + +VD AV+AA
Sbjct: 16 KLIDSPNEQHDPLTNFIGNEF--ARSEKLMDSVNPSTGKPWIKIPDGTAR-EVDQAVEAA 72
Query: 66 RDAFPGWKATPAIEKRDLFYKLAGLLERDIDILSKIESLDTGKPIANNAKYDILEVVEVL 125
++AF WK T ++ L K+A L+E D ++ +ES D GKPI DI V+
Sbjct: 73 KEAFKTWKKTTVQQRSALLNKVANLIEEFNDDIAILESRDQGKPIGLAKVMDIPRCVQNF 132
Query: 126 KYYAGWIDKAGGQSFA---PSSEKLAYTLHQPLGVVGCIIPFNYPLAMMSWKWT-AIATG 181
+ +A + S P+ + + Y + P+GV G I P+N PL ++S+K A+ G
Sbjct: 133 RDFANAALYSLSTSTILEQPTGKFVNYVKNDPVGVAGLISPWNLPLYLLSFKLAPALVAG 192
Query: 182 NTTVFKSADQTPLSILYFAKLVKEAGFPAGVFNVLSGTGASVGSAIVKHTGVDKIAFTGS 241
NT V K ++ T ++ K GFP GV N++ G G S G +V H V I+FTGS
Sbjct: 193 NTVVCKPSEMTSVTAWVLMHAFKLVGFPPGVVNMVIGEGKSAGQRLVDHVDVPLISFTGS 252
Query: 242 TAVGQIIQQQSAVNLKPITLECGGKSANMIFEDCDLEQAVKWSAWGIFNNMGQICSGTSR 301
T +G+ IQ+ A K ++LE GGK+ +++ + + + A F N G+IC TSR
Sbjct: 253 TVIGKKIQEDGAKLNKKVSLEMGGKNPGIVYSNYR-KSDIASIARSSFLNQGEICLCTSR 311
Query: 302 VFVQESIYEEFVAQLADHVKKTYIVGAPSDDAVIVGPQVSKKQQERVLEYIKIGIEEGCK 361
+FVQ+ I+ +FV + KK + VG P+ V +G SK E+V YI++ +EG
Sbjct: 312 LFVQKPIFADFVKSYVEEAKK-FTVGDPTTQ-VQIGAMNSKVHYEKVKSYIELAKKEGAD 369
Query: 362 VPLGGLGAPEPIANDPALANGYYVKPTILADVKASYRIAKEEIFGPVIVVGSFKDYKEAL 421
+ GG+ I N NGY++ PT++ + + ++ +EIFGPV+ + F +E +
Sbjct: 370 ILCGGVTT---IQN--GCENGYFITPTVIVGLHDASKVMTDEIFGPVVCITPFDTAEEVI 424
Query: 422 DIANDSDYGLGSAIFSKDIVTCHKFAQDVEAGMVWINSSNDVDINVPFGGVKMSGHGREL 481
+ AN + YGL + ++S D A ++ AG VW N+ D+++PFGG K SG+GRE
Sbjct: 425 ERANSTPYGLSATVWSSDSDELLNTANELRAGTVWCNTWLARDLSMPFGGCKQSGNGREG 484
Query: 482 GEYGLANFTNVKSVHVNLGRK 502
L +++ K+V VN+ K
Sbjct: 485 LHDSLHFYSDAKTVCVNIAAK 505
>7298784 [F] KOG2452 Formyltetrahydrofolate dehydrogenase
Length = 816
Score = 260 bits (665), Expect = 3e-69
Identities = 148/361 (40%), Positives = 212/361 (57%), Gaps = 9/361 (2%)
Query: 9 ADGTEYQQPLGLFINNEYVEAHGSETLTSYNPSSGEEICKVQCADPKIDVDLAVKAARDA 68
A+ E + P LFIN E+V+A TL NP++ E +CKV CA DVD AV+AA A
Sbjct: 420 ANKREIRVPTQLFINGEFVDAEAQRTLEIVNPTNEEVLCKVACASAT-DVDKAVRAAHSA 478
Query: 69 FPG-WKATPAIEKRDLFYKLAGLLERDIDILSKIESLDTGKPIANNAKYDILEVVEVLKY 127
F G W+ ++ L LA L+ER+ + L+ IES+D+G K + +E +Y
Sbjct: 479 FYGSWRQITPRQRGQLMLNLADLMERNKEELATIESVDSGAVYTLALKTHVGMSIEAWRY 538
Query: 128 YAGWIDKAGGQSF----APSSEKLAYTLHQPLGVVGCIIPFNYPLAMMSWKWTA-IATGN 182
+AGW DK G + A + L +T +P+GV G I P+NYPL M+SWK A IA GN
Sbjct: 539 FAGWCDKIQGNTIPVNPARPNNVLTFTRKEPIGVCGLITPWNYPLMMLSWKMAACIAAGN 598
Query: 183 TTVFKSADQTPLSILYFAKLVKEAGFPAGVFNVLSGTGASVGSAIVKHTGVDKIAFTGST 242
T + K A PL+ L FA+L AGFP GV NVL G G+ G A+ H V K+ FTGST
Sbjct: 599 TCLIKPAQTCPLTALKFAELTVRAGFPPGVINVLPGKGSDAGQAVADHELVRKLGFTGST 658
Query: 243 AVGQIIQQQSA-VNLKPITLECGGKSANMIFEDCDLEQAVKWSAWGIFNNMGQICSGTSR 301
+G+ I + A NLK +LE GGKS +IF DCD+++AVK +F N G+ C R
Sbjct: 659 PIGKHIMKSCADSNLKKCSLELGGKSPLIIFADCDMDKAVKHGMSSVFFNKGENCIAAGR 718
Query: 302 VFVQESIYEEFVAQLADHVKKTYIVGAPSDDAVIVGPQVSKKQQERVLEYIKIGIEEGCK 361
+FV++ I++EF+ ++ + +T +G P D + GPQ K +++LE+ + G++EG K
Sbjct: 719 LFVEDRIHDEFIRRVLKDL-RTMTIGDPLDRSTAHGPQNHKAHFDKLLEFCRRGVDEGAK 777
Query: 362 V 362
+
Sbjct: 778 L 778
>At1g79440 [C] KOG2451 Aldehyde dehydrogenase
Length = 528
Score = 258 bits (658), Expect = 2e-68
Identities = 159/476 (33%), Positives = 263/476 (54%), Gaps = 14/476 (2%)
Query: 22 INNEYVEAHGSETLTSYNPSSGEEICKVQCADPKIDVDLAVKAARDAFPGWKATPAIEKR 81
I ++++++ ++T+ NP++GE I V C K D A+ ++ +AF W A E+
Sbjct: 57 IGGKWLDSYDNKTIKVNNPATGEIIADVACMGTKETND-AIASSYEAFTSWSRLTAGERS 115
Query: 82 DLFYKLAGLLERDIDILSKIESLDTGKPIANNAKYDILEVVEVLKYYAGWIDKAGGQSFA 141
+ + LL + L ++ +L+ GKP+ A ++ ++YYA + G
Sbjct: 116 KVLRRWYDLLIAHKEELGQLITLEQGKPL-KEAIGEVAYGASFIEYYAEEAKRVYGDIIP 174
Query: 142 PS-SEKLAYTLHQPLGVVGCIIPFNYPLAMMSWK-WTAIATGNTTVFKSADQTPLSILYF 199
P+ S++ L QP+GVVG I P+N+PLAM++ K A+A+G T V K ++ TPL+ L
Sbjct: 175 PNLSDRRLLVLKQPVGVVGAITPWNFPLAMITRKVGPALASGCTVVVKPSELTPLTALAA 234
Query: 200 AKLVKEAGFPAGVFNVLSGTGASVGSAIVKHTGVDKIAFTGSTAVGQIIQQQSAVNLKPI 259
A+L +AG P G NV+ G +G A++ V KI FTGSTAVG+ + +A +K +
Sbjct: 235 AELALQAGVPPGALNVVMGNAPEIGDALLTSPQVRKITFTGSTAVGKKLMAAAAPTVKKV 294
Query: 260 TLECGGKSANMIFEDCDLEQAVKWSAWGIFNNMGQICSGTSRVFVQESIYEEFVAQLADH 319
+LE GG + +++F+D DL+ AVK + F N GQ C +RV VQ+ IY++F ++
Sbjct: 295 SLELGGNAPSIVFDDADLDVAVKGTLAAKFRNSGQTCVCANRVLVQDGIYDKFAEAFSEA 354
Query: 320 VKKTYIVGAPSDDAVIVGPQVSKKQQERVLEYIKIGIEEGCKVPLGGLGAPEPIANDPAL 379
V+K VG D GP ++ ++V +++ + +G K+ +GG +L
Sbjct: 355 VQKLE-VGDGFRDGTTQGPLINDAAVQKVETFVQDAVSKGAKIIIGG--------KRHSL 405
Query: 380 ANGYYVKPTILADVKASYRIAKEEIFGPVIVVGSFKDYKEALDIANDSDYGLGSAIFSKD 439
+Y +PT++ DV + ++KEEIFGPV + FK ++A+ IAND+ GL + IF+
Sbjct: 406 GMTFY-EPTVIRDVSDNMIMSKEEIFGPVAPLIRFKTEEDAIRIANDTIAGLAAYIFTNS 464
Query: 440 IVTCHKFAQDVEAGMVWINSSNDVDINVPFGGVKMSGHGRELGEYGLANFTNVKSV 495
+ + + +E G+V +N PFGGVK SG GRE +YG+ + +K V
Sbjct: 465 VQRSWRVFEALEYGLVGVNEGLISTEVAPFGGVKQSGLGREGSKYGMDEYLEIKYV 520
>YBR006w [C] KOG2451 Aldehyde dehydrogenase
Length = 497
Score = 253 bits (647), Expect = 4e-67
Identities = 162/481 (33%), Positives = 265/481 (54%), Gaps = 16/481 (3%)
Query: 21 FINNEYVEAHGSETLTSYNPSSGEEICKVQCADPKIDVDLAVKAARDAFPGWKATPAIEK 80
+I+ ++V+ E +P+SGE I +V P V+ A+ A + F +K T E+
Sbjct: 22 YIDGKWVKGT-DEVFEVVDPASGEIIARVP-EQPVSVVEEAIDVAYETFKTYKNTTPRER 79
Query: 81 RDLFYKLAGLLERDIDILSKIESLDTGKPIANNAKYDILEVVEVLKYYAGWIDKAGGQSF 140
+ L+ ++D L+ I +L+ GK + AK +I ++YA + G +
Sbjct: 80 AKWLRNMYNLMLENLDDLATIITLENGKALGE-AKGEIKYAASYFEWYAEEAPRLYGATI 138
Query: 141 AP-SSEKLAYTLHQPLGVVGCIIPFNYPLAMMSWKWTA-IATGNTTVFKSADQTPLSILY 198
P + +T+ QP+GV G I P+N+P AM++ K A +A G T V K QTPLS L
Sbjct: 139 QPLNPHNRVFTIRQPVGVCGIICPWNFPSAMITRKAAAALAVGCTVVIKPDSQTPLSALA 198
Query: 199 FAKLVKEAGFPAGVFNVL--SGTGASVGSAIVKHTGVDKIAFTGSTAVGQIIQQQSAVNL 256
A L ++AGFP G FNV+ +G + + V K+ FTGST VG+I+ +QS+ L
Sbjct: 199 MAYLAEKAGFPKGSFNVILSHANTPKLGKTLCESPKVKKVTFTGSTNVGKILMKQSSSTL 258
Query: 257 KPITLECGGKSANMIFEDCDLEQAVKWSAWGIFNNMGQICSGTSRVFVQESIYEEFVAQL 316
K ++ E GG + ++FED DL+QA++ + F +GQ C +R++V SI ++F L
Sbjct: 259 KKLSFELGGNAPFIVFEDADLDQALEQAMACKFRGLGQTCVCANRLYVHSSIIDKFAKLL 318
Query: 317 ADHVKKTYIVGAPSDDAVIVGPQVSKKQQERVLEYIKIGIEEGCKVPLGGLGAPEPIAND 376
A+ VKK +++G D G ++ E+V + + I++G KV L G E
Sbjct: 319 AERVKK-FVIGHGLDPKTTHGCVINSSAIEKVERHKQDAIDKGAKVVLEGGRLTE----- 372
Query: 377 PALANGYYVKPTILADVKASYRIAKEEIFGPVIVVGSFKDYKEALDIANDSDYGLGSAIF 436
L +Y P IL+ V ++ ++KEE FGP+ + SF +E + AND+++GL + +F
Sbjct: 373 --LGPNFYA-PVILSHVPSTAIVSKEETFGPLCPIFSFDTMEEVVGYANDTEFGLAAYVF 429
Query: 437 SKDIVTCHKFAQDVEAGMVWINSSNDVDINVPFGGVKMSGHGRELGEYGLANFTNVKSVH 496
SK++ T + ++ +E GMV N+ D ++PFGGVK SG GRE YG+ ++T +K++
Sbjct: 430 SKNVNTLYTVSEALETGMVSCNTGVFSDCSIPFGGVKESGFGREGSLYGIEDYTVLKTIT 489
Query: 497 V 497
+
Sbjct: 490 I 490
>SPAC1002.12c [C] KOG2451 Aldehyde dehydrogenase
Length = 498
Score = 248 bits (632), Expect = 2e-65
Identities = 156/485 (32%), Positives = 261/485 (53%), Gaps = 14/485 (2%)
Query: 17 PLGLFINNEYVEAHGSETLTSYNPSSGEEICKVQCADPKIDVDLAVKAARDAFPGWKATP 76
P +I ++V A +T NP E + V + + A+K A +AF ++ +
Sbjct: 23 PARSYIGGKWVTAASGKTFDVENPGLNETLAPVTDMSVE-ETRKAIKVAHEAFLSYRNSD 81
Query: 77 AIEKRDLFYKLAGLLERDIDILSKIESLDTGKPIANNAKYDILEVVEVLKYYAGWIDKAG 136
E+ + + L+ + D L+ + +L+ GK + + AK +++ + + ++AG +
Sbjct: 82 IKERYAILRRWYDLIMENADDLATMMTLENGKALGD-AKGEVVYAAKFIDWFAGEALRIS 140
Query: 137 GQSFAPSS-EKLAYTLHQPLGVVGCIIPFNYPLAMMSWK-WTAIATGNTTVFKSADQTPL 194
G S S+ + T+ QP+GVVG I P+N+P AM++ K A+A G T V + A +TP
Sbjct: 141 GDSSMSSNPQNRIITIKQPVGVVGIITPWNFPAAMITRKVGAALAAGCTVVIRPAAETPF 200
Query: 195 SILYFAKLVKEAGFPAGVFNVLSGTGASV-GSAIVKHTGVDKIAFTGSTAVGQIIQQQSA 253
+ L AKL + AG PAGV N+++ S G + + + K++FTGST VG+I+ +QS+
Sbjct: 201 TALALAKLAERAGVPAGVLNMVTANSPSEHGIELTTNPLIRKVSFTGSTNVGKILAKQSS 260
Query: 254 VNLKPITLECGGKSANMIFEDCDLEQAVKWSAWGIFNNMGQICSGTSRVFVQESIYEEFV 313
LK ++LE GG + ++FED DLE+A F GQ C +R++V S+Y+ FV
Sbjct: 261 STLKKLSLELGGNAPFIVFEDADLEKAADALMACKFRGSGQTCVCANRIYVHSSVYDAFV 320
Query: 314 AQLADHVKKTYIVGAPSDDAVIVGPQVSKKQQERVLEYIKIGIEEGCKVPLGGLGAPEPI 373
+ + V K + +G D V GP +S+K +V ++++ +++G V GG A
Sbjct: 321 DLVTERVSK-FKLGYGLDAGVTHGPLISEKAISKVKQHVEDAVQKGGVVVTGGKVASN-- 377
Query: 374 ANDPALANGYYVKPTILADVKASYRIAKEEIFGPVIVVGSFKDYKEALDIANDSDYGLGS 433
Y +PT++ + K I++EE FGPV + F E + ANDS GL
Sbjct: 378 ------LGPMYFEPTVIINAKQGMLISEEETFGPVGALFKFDTEDEVVAWANDSPVGLAG 431
Query: 434 AIFSKDIVTCHKFAQDVEAGMVWINSSNDVDINVPFGGVKMSGHGRELGEYGLANFTNVK 493
+FSKDI + + ++ GMV N+ D+ PFGGVK SG GRE +YG++ + ++K
Sbjct: 432 YLFSKDISRVFRVGEALQVGMVGCNTGLVSDVLSPFGGVKESGFGREGSKYGISEYLDIK 491
Query: 494 SVHVN 498
S+ ++
Sbjct: 492 SLTIS 496
>7301355 [C] KOG2451 Aldehyde dehydrogenase
Length = 509
Score = 239 bits (610), Expect = 7e-63
Identities = 154/474 (32%), Positives = 258/474 (53%), Gaps = 20/474 (4%)
Query: 29 AHGSETLTSYNPSSGEEICKVQCADPKIDVDLAVKAARDAFPG--WKATPAIEKRDLFYK 86
++ T NP++G I KV D A+ AA+ A+ W++ A ++ +L K
Sbjct: 41 SNAKATFEVRNPANGAVIGKVPNMTVA-DAQKAIDAAKQAYESKEWRSLTAKDRSNLLKK 99
Query: 87 LAGLLERDIDILSKIESLDTGKPIANNAKYDILEVVEVLKYYAGWIDKAGGQ---SFAPS 143
L+E+ +++I + ++GKPI N +K ++ ++++A + G+ S +P+
Sbjct: 100 WHKLIEQHSQEIAEIMTAESGKPI-NESKGEVAYGNAFVEWFAEEARRIYGEIVPSASPN 158
Query: 144 SEKLAYTLHQPLGVVGCIIPFNYPLAMMSWK-WTAIATGNTTVFKSADQTPLSILYFAKL 202
E + + QP+GV I P+N+P+AM++ K A+A G T V K ++ TPL+ L AKL
Sbjct: 159 REIIV--MKQPIGVAALITPWNFPMAMITRKAGAALAAGCTVVVKPSEDTPLTALAVAKL 216
Query: 203 VKEAGFPAGVFNVLS-GTGASVGSAIVKHTGVDKIAFTGSTAVGQIIQQQSAVNLKPITL 261
+AG P GV NV++ A +G K V I+FTGST VG+++ + SA +K I L
Sbjct: 217 AVDAGIPKGVINVVTTNKAAPIGDLFCKSPDVRGISFTGSTEVGKLLFRNSADGIKRICL 276
Query: 262 ECGGKSANMIFEDCDLEQAVKWSAWGIFNNMGQICSGTSRVFVQESIYEEFVAQLADHVK 321
E GG + ++F+ D+E+AV + F N GQ C +R FVQ+S+Y++FV QL V+
Sbjct: 277 ELGGNAPFIVFDSADIEKAVDGAMASKFRNCGQTCVSANRFFVQDSVYDKFVGQLKKRVE 336
Query: 322 KTYIVGAPSDDAVIVGPQVSKKQQERVLEYIKIGIEEGCKVPLGGLGAPEPIANDPALAN 381
I D V +GP +++ Q +V +++ + + LGG P+
Sbjct: 337 ALKIGDGQGCD-VQIGPLINEMQFNKVSGFVEDARSKKANIILGGQPLPDK--------G 387
Query: 382 GYYVKPTILADVKASYRIAKEEIFGPVIVVGSFKDYKEALDIANDSDYGLGSAIFSKDIV 441
+ PTI+ DV S ++ EE+FGPV+ + F+D +EA+ AND+ GL +S+++
Sbjct: 388 SLFYAPTIVTDVPPSAQLYSEEVFGPVVSIIRFRDEEEAVKKANDTRRGLAGYFYSENLQ 447
Query: 442 TCHKFAQDVEAGMVWINSSNDVDINVPFGGVKMSGHGRELGEYGLANFTNVKSV 495
+ A+ +E GMV +N PFGGVK SG GRE ++G+ ++ ++K +
Sbjct: 448 QVFRVAKRLEVGMVGVNEGIISAAEAPFGGVKESGVGREGSKHGIDDYVDIKYI 501
>Hs4507229 [C] KOG2451 Aldehyde dehydrogenase
Length = 535
Score = 236 bits (603), Expect = 5e-62
Identities = 154/480 (32%), Positives = 252/480 (52%), Gaps = 18/480 (3%)
Query: 21 FINNEYVEAHGSETLTSYNPSSGEEICKVQCADPKIDVDLAVKAARDAFPGWKATPAIEK 80
F+ ++ A + T +P+SG + V + + AV+AA +AF W+ A E+
Sbjct: 64 FVGGRWLPA--AATFPVQDPASGAALGMVADCGVR-EARAAVRAAYEAFCRWREVSAKER 120
Query: 81 RDLFYKLAGLLERDIDILSKIESLDTGKPIANNAKYDILEVVEVLKYYAGWIDKAGGQSF 140
L K L+ ++ D L++I + ++GKP+ A +IL L++++ + G
Sbjct: 121 SSLLRKWYNLMIQNKDDLARIITAESGKPL-KEAHGEILYSAFFLEWFSEEARRVYGDII 179
Query: 141 -APSSEKLAYTLHQPLGVVGCIIPFNYPLAMMSWK-WTAIATGNTTVFKSADQTPLSILY 198
P+ ++ A L QP+GV I P+N+P AM++ K A+A G T V K A+ TP S L
Sbjct: 180 HTPAKDRRALVLKQPIGVAAVITPWNFPSAMITRKVGAALAAGCTVVVKPAEDTPFSALA 239
Query: 199 FAKLVKEAGFPAGVFNVLSGT---GASVGSAIVKHTGVDKIAFTGSTAVGQIIQQQSAVN 255
A+L +AG P+GV+NV+ + VG AI V KI+FTGST G+I+ +A +
Sbjct: 240 LAELASQAGIPSGVYNVIPCSRKNAKEVGEAICTDPLVSKISFTGSTTTGKILLHHAANS 299
Query: 256 LKPITLECGGKSANMIFEDCDLEQAVKWSAWGIFNNMGQICSGTSRVFVQESIYEEFVAQ 315
+K +++E GG + ++F+ +++QAV + F N GQ C +++ VQ I++ FV
Sbjct: 300 VKRVSMELGGLAPFIVFDSANVDQAVAGAMASKFRNTGQTCVCSNQFLVQRGIHDAFVKA 359
Query: 316 LADHVKKTYIVGAPSDDAVIVGPQVSKKQQERVLEYIKIGIEEGCKVPLGGLGAPEPIAN 375
A+ +KK VG ++ GP +++K E+V + + + +G V GG
Sbjct: 360 FAEAMKKNLRVGNGFEEGTTQGPLINEKAVEKVEKQVNDAVSKGATVVTGG--------K 411
Query: 376 DPALANGYYVKPTILADVKASYRIAKEEIFGPVIVVGSFKDYKEALDIANDSDYGLGSAI 435
L ++ +PT+L +V EE FGP+ V F +EA+ IAN +D GL
Sbjct: 412 RHQLGKNFF-EPTLLCNVTQDMLCTHEETFGPLAPVIKFDTEEEAIAIANAADVGLAGYF 470
Query: 436 FSKDIVTCHKFAQDVEAGMVWINSSNDVDINVPFGGVKMSGHGRELGEYGLANFTNVKSV 495
+S+D + A+ +E GMV +N + PFGGVK SG GRE +YG+ + +K V
Sbjct: 471 YSQDPAQIWRVAEQLEVGMVGVNEGLISSVECPFGGVKQSGLGREGSKYGIDEYLELKYV 530
>CE10542 [C] KOG2451 Aldehyde dehydrogenase
Length = 569
Score = 225 bits (574), Expect = 1e-58
Identities = 149/478 (31%), Positives = 250/478 (52%), Gaps = 20/478 (4%)
Query: 21 FINNEYVEAHGSETLTSYNPSSGEEICKVQCADPKIDVDLAVKAARDAFPGWKATPAIEK 80
+I ++ + + NP + E + + K D + AV +A + F W T + ++
Sbjct: 21 YIGGKWTASETGNSFDVLNPFNNEVVDRATNCTVK-DAEKAVHSALEGFDKWAHTYSAKQ 79
Query: 81 RD-LFYKLAGLLERDIDILSKIESLDTGKPIANNAKYDILEVVEVLKYYAGWIDKAGGQS 139
R + +K +L + L+ + + + GKP+A A+ +I +YAG + GQ
Sbjct: 80 RGAILHKWFEILVQRETELATLLTKEQGKPLAE-ARGEIQYSAAYFDWYAGEARRVYGQ- 137
Query: 140 FAPSSEKLAYTLH--QPLGVVGCIIPFNYPLAMMSWKWTA-IATGNTTVFKSADQTPLSI 196
PS+ LH +P+GVV I P+N+P AM++ K A ++ G + V K + TPLS
Sbjct: 138 VVPSAVVNRLHLHTREPIGVVALIAPWNFPTAMIARKAAAALSVGCSAVVKPSGDTPLSA 197
Query: 197 LYFAKLVKEAGFPAGVFNVLSG---TGASVGSAIVKHTGVDKIAFTGSTAVGQIIQQQSA 253
L A+ +EAG PAGVFNV++ A + + + T V I+FTGST VG+++ QSA
Sbjct: 198 LALAQTAEEAGIPAGVFNVITADHSNTAEISKYLCESTDVSAISFTGSTPVGKLLLAQSA 257
Query: 254 VNLKPITLECGGKSANMIFEDCDLEQAVKWSAWGIFNNMGQICSGTSRVFVQESIYEEFV 313
+K + LE GG + ++F+D DL+ AV + F GQ C +R++V E I+++++
Sbjct: 258 STVKRVCLELGGNAPLIVFDDADLDVAVNGTMATKFRCSGQTCVSANRIYVHEKIHDQYI 317
Query: 314 AQLADHVKKTYIVGAPSDDAVIVGPQVSKKQQERVLEYIKIGIEEGCKVPLGGLGAPEPI 373
++LA +K+ ++G + GP V++K ++ + + +G ++ GG
Sbjct: 318 SKLAAAMKEKLVLGDGLNPKTTQGPLVNQKAVDKCELLLSDALGKGSELICGGKRG---- 373
Query: 374 ANDPALANGYYVKPTILADVKASYRIAKEEIFGPVIVVGSFKDYKEALDIANDSDYGLGS 433
+G +PT++ +V+++ IA EIFGP+ V F+D +E L+ AN+ GL
Sbjct: 374 ------EHGTSYEPTLITNVQSNTNIAHTEIFGPIASVQKFRDEQEVLEAANNCRVGLAG 427
Query: 434 AIFSKDIVTCHKFAQDVEAGMVWINSSNDVDINVPFGGVKMSGHGRELGEYGLANFTN 491
+F +D + A+ +E GMV +N FGGVK SG GRE G G+ FTN
Sbjct: 428 YVFGRDQSRLQRVARKLEVGMVGVNEGLISCAEAAFGGVKESGIGREGGAQGIDEFTN 485
>CE02183 [EG] KOG2449 Methylmalonate semialdehyde dehydrogenase
Length = 523
Score = 211 bits (537), Expect = 2e-54
Identities = 154/486 (31%), Positives = 252/486 (51%), Gaps = 25/486 (5%)
Query: 20 LFINNEYVEAHGSETLTSYNPSSGEEICKVQCADPKIDVDLAVKAARDAFPGWKATPAIE 79
L+I+ + VE+ ++ + NP++ E I V A + ++ AV +A++AF WK T +
Sbjct: 32 LWIDGQAVESKTTDFVELTNPATNEVIAMVPNAT-QAEMQAAVDSAKNAFNTWKNTSPLT 90
Query: 80 KRDLFYKLAGLLERDIDILSKIESLDTGKPIANNAKYDILEVVEVLKYYAGWIDKAGGQS 139
++ +KL L++RD+ L++ +++ GK + + A+ D+ ++V+++ G++
Sbjct: 91 RQQCMFKLQALIKRDMKKLAESITIEQGKTLPD-AEGDVSRGLQVVEHACSVPSLMMGET 149
Query: 140 FAPSSEKL-AYTLHQPLGVVGCIIPFNYPLAMMSWKW-TAIATGNTTVFKSADQTPLSIL 197
S + ++ PLGV I PFN+P + W + A+ATGNT V K ++Q P +
Sbjct: 150 LPNVSRDMDTHSYRIPLGVTAGICPFNFPAMIPLWMFPVALATGNTMVIKPSEQDPGAAQ 209
Query: 198 YFAKLVKEAGFPAGVFNVLSGTGASVGSAIVKHTGVDKIAFTGSTAVGQIIQQQSAVNLK 257
+L KEAG P G N++ G ++V + I + + I+F G A G+ I ++ A N K
Sbjct: 210 LLVELAKEAGVPDGCVNIIHGQHSAV-NFICDNPDIKAISFVGGDAAGKHIYERGAKNGK 268
Query: 258 PITLECGGKSANMIFEDCDLEQAVKWSAWGIFNNMGQICSG-TSRVFVQESIYEEFVAQL 316
+ G K+ +I D + EQ + F GQ C T+ V V E+ ++ +L
Sbjct: 269 RVQSNMGAKNHGVIMADANKEQTLNQLTAAAFGAAGQRCMALTTAVLVGEA--RAWLPEL 326
Query: 317 ADHVKKTYIVGAPSDDAVIVGPQVSKKQQERVLEYIKIGIEEGCKVPLGGLGAPEPIAND 376
+ K + D I GP +SK+ + RVL I+ +EG +VPL G P
Sbjct: 327 VEKAKNLKVNAGWKPDTDI-GPLISKQSKARVLRLIESAKKEGAQVPLDGSNITVP---- 381
Query: 377 PALANGYYVKPTILADVKASYRIAKEEIFGPVIVVGSFKDYKEALDIANDSDYGLGSAIF 436
NG +V PTILA VK + +EEIFGPV+VV ++ EA++I N++ YG G+AIF
Sbjct: 382 -GFENGNFVGPTILAGVKPNMTCYREEIFGPVLVVMEAENLNEAIEIINNNPYGNGTAIF 440
Query: 437 SKDIVTCHKFAQDVEAGMVWINSSNDVDINVPFGGVKMSG-HGRELGE---YGLAN---F 489
+ + T KF +V+ G + IN V I VP +G G LG+ YG A +
Sbjct: 441 TSNGATARKFTNEVDVGQIGIN----VPIPVPLPMFSFTGSRGSFLGDLNFYGKAGIQFY 496
Query: 490 TNVKSV 495
T K+V
Sbjct: 497 TQWKTV 502
>At2g14170 [EG] KOG2449 Methylmalonate semialdehyde dehydrogenase
Length = 607
Score = 206 bits (525), Expect = 5e-53
Identities = 154/507 (30%), Positives = 247/507 (48%), Gaps = 29/507 (5%)
Query: 2 SFTSIKLADGTEYQQPLGL--FINNEYVEAHGSETLTSYNPSSGEEICKVQCADPKIDVD 59
S+ S T+ Q P + I +VE+ S + NP++ E + KV + +
Sbjct: 96 SWLSTSPEQSTQPQMPPRVPNLIGGSFVESQSSSFIDVINPATQEVVSKVPLTTNE-EFK 154
Query: 60 LAVKAARDAFPGWKATPAIEKRDLFYKLAGLLERDIDILSKIESLDTGKPIANNAKYDIL 119
AV AA+ AFP W+ TP ++ + K L+ +++D L+ + + GK + ++ DI
Sbjct: 155 AAVSAAKQAFPLWRNTPITTRQRVMLKFQELIRKNMDKLAMNITTEQGKTL-KDSHGDIF 213
Query: 120 EVVEVLKYYAGWIDKAGGQSFAPSSEKL-AYTLHQPLGVVGCIIPFNYPLAMMSWKW-TA 177
+EV+++ G G+ S + Y++ +PLGV I PFN+P + W + A
Sbjct: 214 RGLEVVEHACGMATLQMGEYLPNVSNGVDTYSIREPLGVCAGICPFNFPAMIPLWMFPVA 273
Query: 178 IATGNTTVFKSADQTPLSILYFAKLVKEAGFPAGVFNVLSGTGASVGSAIVKHTGVDKIA 237
+ GNT + K +++ P + + A+L EAG P GV N++ GT +V +AI + ++
Sbjct: 274 VTCGNTFILKPSEKDPGASVILAELAMEAGLPDGVLNIVHGTNDTV-NAICDDEDIRAVS 332
Query: 238 FTGSTAVGQIIQQQSAVNLKPITLECGGKSANMIFEDCDLEQAVKWSAWGIFNNMGQICS 297
F GS G I ++A K I G K+ ++ D +++ + F GQ C
Sbjct: 333 FVGSNTAGMHIYARAAAKGKRIQSNMGAKNHGLVLPDANIDATLNALLAAGFGAAGQRCM 392
Query: 298 GTSRV-FVQESIYEEFVAQLADHVKKTYIVGAPSDDAVIVGPQVSKKQQERVLEYIKIGI 356
S V FV ++ + + +L + K + DA + GP +SK+ +ER+ I+ G+
Sbjct: 393 ALSTVVFVGDA--KSWEDKLVERAKALKVTCGSEPDADL-GPVISKQAKERICRLIQSGV 449
Query: 357 EEGCKVPLGGLGAPEPIANDPALANGYYVKPTILADVKASYRIAKEEIFGPVIVVGSFKD 416
++G K+ L G P G ++ PTIL+ V KEEIFGPV+V
Sbjct: 450 DDGAKLLLDGRDIVVP-----GYEKGNFIGPTILSGVTPDMECYKEEIFGPVLVCMQANS 504
Query: 417 YKEALDIANDSDYGLGSAIFSKDIVTCHKFAQDVEAGMVWINSSNDVDINVP-----FGG 471
+ EA+ I N + YG G+AIF+ KF D+EAG + IN V I VP F G
Sbjct: 505 FDEAISIINKNKYGNGAAIFTSSGAAARKFQMDIEAGQIGIN----VPIPVPLPFFSFTG 560
Query: 472 VKMSGHGRELGEYGLAN---FTNVKSV 495
K S G +L YG A FT +K+V
Sbjct: 561 NKASFAG-DLNFYGKAGVDFFTQIKTV 586
>SPBC21C3.15c [C] KOG2454 Betaine aldehyde dehydrogenase
Length = 522
Score = 205 bits (521), Expect = 1e-52
Identities = 138/478 (28%), Positives = 235/478 (48%), Gaps = 26/478 (5%)
Query: 32 SETLTSYNPSSGEEICKVQCADPKIDVDLAVKAARDAFPGWKATPAIEKRDLFYKLAGLL 91
S TLT Y P G + +V+ + K D+D ++ A +A WK+T E+R+ L +
Sbjct: 2 SSTLTCYCPGDGSLLGEVKLFN-KSDIDQSIILAEEAQKEWKSTSFAERRNFLKALKENI 60
Query: 92 ERDIDILSKIESLDTGKPIANNAKYDILEVVEVLKYYAGWIDKAGGQSFAPS-------- 143
R+ D ++I DTGK + + A +IL +E + W G QS P+
Sbjct: 61 IRNQDKYAEIACKDTGKTLVDAAFGEILVTLEKIN----WTLANGEQSLRPTKRPNSLLT 116
Query: 144 SEKLAYTLHQPLGVVGCIIPFNYPLA-MMSWKWTAIATGNTTVFKSADQTPLSILYFAKL 202
S K Y ++PLGV+ ++ +NYPL + +A+ GN V K ++ T S + ++
Sbjct: 117 SYKGGYVKYEPLGVIAALVSWNYPLHNALGPIISALFAGNAIVVKGSELTAWSTHQYCEM 176
Query: 203 VKEA----GFPAGVFNVLSGTGASVGSAIVKHTGVDKIAFTGSTAVGQIIQQQSAVNLKP 258
V+ G + ++ V + H+G+ I F GS + +++ +A L P
Sbjct: 177 VRSLLQSMGHSPELVQCITCL-PDVADHLTSHSGIKHITFIGSQPIAKLVAASAAKQLTP 235
Query: 259 ITLECGGKSANMIFEDCDLEQAVKWSAWGIFNNMGQICSGTSRVFVQESIYEEFVAQLAD 318
+ LE GGK ++ +D LE+ + G+F + GQ C G R+ + +Y+ + +L +
Sbjct: 236 LCLELGGKDPCILTDDHRLEEILSIVMRGVFQSAGQNCIGIERIIALDGVYDTIITKLYN 295
Query: 319 HVKKTYIVGAPSDDAVIVGPQVSKKQQERVLEYIKIGIEEGCKVPLGGLGAPEPIANDPA 378
+ T +G + + V +G VS + + + I+ + +G ++ GG P
Sbjct: 296 RIS-TMRLGMYTQNDVDMGAMVSNNRFDHLESLIQDAVSKGARLVYGGHRFQHP-----K 349
Query: 379 LANGYYVKPTILADVKASYRIAKEEIFGPVIVVGSFKDYKEALDIANDSDYGLGSAIFSK 438
G Y PT+L D +IA+EE F P+ +V K + AL+IAN +++GLG+++F +
Sbjct: 350 YPKGNYFLPTLLVDATNEMKIAQEECFAPIALVFRAKSPEHALEIANGTEFGLGASVFGR 409
Query: 439 DIVTCHKFAQDVEAGMVWINSSNDVD-INVPFGGVKMSGHGRELGEYGLANFTNVKSV 495
D C F ++E GMV +N + +PFGG K SG+GR G GL N K++
Sbjct: 410 DKQLCQYFTDNLETGMVAVNDFGAFYLLQMPFGGCKKSGYGRFAGYEGLRGICNSKAI 467
>At1g54100 [C] KOG2453 Aldehyde dehydrogenase
Length = 508
Score = 204 bits (518), Expect = 3e-52
Identities = 147/499 (29%), Positives = 249/499 (49%), Gaps = 33/499 (6%)
Query: 18 LGLFINNEYVEAHGSETLTSYNPSSGEEICKVQCADPKIDVDLAVKAARDAFPGWKATPA 77
LG ++ ++ +A+G +++ NP++ + I +V A + D + +KA +A W A
Sbjct: 21 LGSYVAGKW-QANGP-LVSTLNPANNQPIAQVVEASLE-DYEQGLKACEEAAKIWMQVTA 77
Query: 78 IEKRDLFYKLAGLLERDIDILSKIESLDTGKPIANNAKYDILEVVEVLKYYAGWIDKAGG 137
++ D+ ++ L +D L ++ SL+ GK +A ++ EV+++ + G + G
Sbjct: 78 PKRGDIVRQIGDALRSKLDYLGRLLSLEMGKILAEGIG-EVQEVIDMCDFAVGLSRQLNG 136
Query: 138 QSFAPSSEK--LAYTLHQPLGVVGCIIPFNYPLAMMSWK-WTAIATGNTTVFKSADQTPL 194
S PS + + PLG+VG I FN+P A++ W A+ GN V+K A TPL
Sbjct: 137 -SVIPSERPNHMMLEMWNPLGIVGVITAFNFPCAVLGWNACIALVCGNCVVWKGAPTTPL 195
Query: 195 SILYFAKLVKEA----GFPAGVFNVLSGTGASVGSAIVKHTGVDKIAFTGSTAVGQIIQQ 250
+ KLV E P +F + G GA +G AI K T + ++FTGS+ VG ++QQ
Sbjct: 196 ITIAMTKLVAEVLEKNNLPGAIFTAMCG-GAEIGEAIAKDTRIPLVSFTGSSRVGSMVQQ 254
Query: 251 QSAVNLKPITLECGGKSANMIFEDCDLEQAVKWSAWGIFNNMGQICSGTSRVFVQESIYE 310
LE G +A ++ +D D++ A + + GQ C+ R+ + ES+Y+
Sbjct: 255 TVNARSGKTLLELSGNNAIIVMDDADIQLAARSVLFAAVGTAGQRCTTCRRLLLHESVYD 314
Query: 311 EFVAQLADHVKKTYIVGAPSDDAVIVGP---QVSKKQQERVLEYIKIGIEEGCKVPLGGL 367
+ + QL K+ I G P + ++GP SKK E+ +E IK +G K+ GG
Sbjct: 315 KVLEQLLTSYKQVKI-GNPLEKGTLLGPLHTPESKKNFEKGIEVIK---SQGGKILTGGK 370
Query: 368 GAPEPIANDPALANGYYVKPTILADVKASYRIAKEEIFGPVIVVGSFKDYKEALDIANDS 427
G +V+PTI+ ++ A + KEE+F PV+ V FK + EA+ I N
Sbjct: 371 AVE---------GEGNFVEPTII-EISADAAVVKEELFAPVLYVLKFKSFGEAVAINNSV 420
Query: 428 DYGLGSAIFSKDIVTCHKFAQDV--EAGMVWIN-SSNDVDINVPFGGVKMSGHGRELGEY 484
GL S+IF+++ ++ + + G+V +N +N +I FGG K +G GRE G
Sbjct: 421 PQGLSSSIFTRNPENIFRWIGPLGSDCGIVNVNIPTNGAEIGGAFGGEKATGGGREAGSD 480
Query: 485 GLANFTNVKSVHVNLGRKL 503
+ + +N G +L
Sbjct: 481 SWKQYMRRSTCTINYGNEL 499
>Hs11095441 [EG] KOG2449 Methylmalonate semialdehyde dehydrogenase
Length = 535
Score = 202 bits (515), Expect = 7e-52
Identities = 139/486 (28%), Positives = 250/486 (50%), Gaps = 25/486 (5%)
Query: 20 LFINNEYVEAHGSETLTSYNPSSGEEICKVQCADPKIDVDLAVKAARDAFPGWKATPAIE 79
LFI ++VE+ + + +NP++ E I +V A K ++D A+ + + AFP W T +
Sbjct: 42 LFIGGKFVESKSDKWIDIHNPATNEVIGRVPQAT-KAEMDAAIASCKRAFPAWADTSVLS 100
Query: 80 KRDLFYKLAGLLERDIDILSKIESLDTGKPIANNAKYDILEVVEVLKYYAGWIDKAGGQS 139
++ + + L++ ++ ++K+ +L+ GK +A+ A+ D+ ++V+++ G++
Sbjct: 101 RQQVLLRYQQLIKENLKEIAKLITLEQGKTLAD-AEGDVFRGLQVVEHACSVTSLMMGET 159
Query: 140 FAPSSEKL-AYTLHQPLGVVGCIIPFNYPLAMMSWKWT-AIATGNTTVFKSADQTPLSIL 197
++ + Y+ PLGV I PFN+P + W + A+ GNT + K +++ P + +
Sbjct: 160 MPSITKDMDLYSYRLPLGVCAGIAPFNFPAMIPLWMFPMAMVCGNTFLMKPSERVPGATM 219
Query: 198 YFAKLVKEAGFPAGVFNVLSGTGASVGSAIVKHTGVDKIAFTGSTAVGQIIQQQSAVNLK 257
AKL++++G P G N++ G +V + I H + I+F GS G+ I ++ + + K
Sbjct: 220 LLAKLLQDSGAPDGTLNIIHGQHEAV-NFICDHPDIKAISFVGSNKAGEYIFERGSRHGK 278
Query: 258 PITLECGGKSANMIFEDCDLEQAVKWSAWGIFNNMGQICSGTSR-VFVQESIYEEFVAQL 316
+ G K+ ++ D + E + F GQ C S V V E+ ++++ +L
Sbjct: 279 RVQANMGAKNHGVVMPDANKENTLNQLVGAAFGAAGQRCMALSTAVLVGEA--KKWLPEL 336
Query: 317 ADHVKKTYIVGAPSDDAVIVGPQVSKKQQERVLEYIKIGIEEGCKVPLGGLGAPEPIAND 376
+H K V A +GP ++ + +ERV I G +EG + L G
Sbjct: 337 VEHAKNLR-VNAGDQPGADLGPLITPQAKERVCNLIDSGTKEGASILLDGRKIKVK---- 391
Query: 377 PALANGYYVKPTILADVKASYRIAKEEIFGPVIVVGSFKDYKEALDIANDSDYGLGSAIF 436
NG +V PTI+++VK + KEEIFGPV+VV + EA+ I N++ YG G+AIF
Sbjct: 392 -GYENGNFVGPTIISNVKPNMTCYKEEIFGPVLVVLETETLDEAIQIVNNNPYGNGTAIF 450
Query: 437 SKDIVTCHKFAQDVEAGMVWINSSNDVDINVP-----FGGVKMS--GHGRELGEYGLANF 489
+ + T K+A V+ G V +N V I VP F G + S G G+ G+ +
Sbjct: 451 TTNGATARKYAHLVDVGQVGVN----VPIPVPLPMFSFTGSRSSFRGDTNFYGKQGIQFY 506
Query: 490 TNVKSV 495
T +K++
Sbjct: 507 TQLKTI 512
>7290043 [EG] KOG2449 Methylmalonate semialdehyde dehydrogenase
Length = 552
Score = 201 bits (512), Expect = 2e-51
Identities = 142/486 (29%), Positives = 252/486 (51%), Gaps = 25/486 (5%)
Query: 20 LFINNEYVEAHGSETLTSYNPSSGEEICKVQCADPKIDVDLAVKAARDAFPGWKATPAIE 79
LFI+ ++VE+ +E + ++P++ + + +V A + ++ A+++ + AF W +
Sbjct: 60 LFIDGKFVESKTNEWIDVHDPATNQVVTRVPKAT-QAEMQAALESNKKAFRSWSNQSILT 118
Query: 80 KRDLFYKLAGLLERDIDILSKIESLDTGKPIANNAKYDILEVVEVLKYYAGWIDKAGGQS 139
++ + +KL L++ ++ L+K + + GK +A+ A+ D+L ++V+++ G++
Sbjct: 119 RQQVMFKLQALIKENMGELAKNITKEQGKTLAD-AEGDVLRGLQVVEHCCSIPSLQMGET 177
Query: 140 FAPSSEKL-AYTLHQPLGVVGCIIPFNYPLAMMSWKW-TAIATGNTTVFKSADQTPLSIL 197
A + + Y+L PLGV + PFN+P + W + AI TGNT + K +++ P + +
Sbjct: 178 VANVARDMDTYSLVLPLGVTAGVAPFNFPAMIPLWMFPVAITTGNTMLLKPSERVPGATM 237
Query: 198 YFAKLVKEAGFPAGVFNVLSGTGASVGSAIVKHTGVDKIAFTGSTAVGQIIQQQSAVNLK 257
+L+ EAG P GV NV+ G +V + I + ++F GS G+ I +++ N K
Sbjct: 238 LLMELLNEAGCPPGVVNVIHGQHDAV-NFICDAPEIKAVSFVGSDQAGKYIYERAGKNGK 296
Query: 258 PITLECGGKSANMIFEDCDLEQAVKWSAWGIFNNMGQICSGTSR-VFVQESIYEEFVAQL 316
+ G K+ +I D + E + A F GQ C S VFV ++ + ++ L
Sbjct: 297 RVQSNMGAKNHGIILGDANKENTLNQLAGAAFGAAGQRCMALSTAVFVGDA--QAWIPDL 354
Query: 317 ADHVKKTYIVGAPSDDAVIVGPQVSKKQQERVLEYIKIGIEEGCKVPLGGLGAPEPIAND 376
+ +K V A VGP +S ++R+ + I+ G++EG K+ L G P D
Sbjct: 355 VERAQKLK-VNAGHVPGTDVGPVISAASRQRINDLIESGVKEGAKLILDGRKITVPGYED 413
Query: 377 PALANGYYVKPTILADVKASYRIAKEEIFGPVIVVGSFKDYKEALDIANDSDYGLGSAIF 436
GY+V PTIL+DV S + EEIFGPV+V+ +A+ I N + YG G+A+F
Sbjct: 414 -----GYFVGPTILSDVTPSMKCYTEEIFGPVLVILKADTLDDAIGIVNANPYGNGTAVF 468
Query: 437 SKDIVTCHKFAQDVEAGMVWINSSNDVDINVP-----FGGVKMSGHGRE--LGEYGLANF 489
+ + KF +++AG V +N V I VP F G + S G G+ G+ +
Sbjct: 469 TTNGAAARKFVNEIDAGQVGVN----VPIPVPLPMFSFTGTRGSFRGDHHFYGKQGIKFY 524
Query: 490 TNVKSV 495
T K+V
Sbjct: 525 TQTKTV 530
>At3g66658 [C] KOG2454 Betaine aldehyde dehydrogenase
Length = 578
Score = 201 bits (510), Expect = 3e-51
Identities = 148/501 (29%), Positives = 243/501 (47%), Gaps = 41/501 (8%)
Query: 27 VEAHGSETLTS---YNPSSG---EEICKVQCADPKI-------------DVDLAVKAARD 67
V AHG +T + Y P G + KVQC +P +V+ V +R
Sbjct: 38 VLAHGKDTEENSFIYIPPRGRSQQSDKKVQCYEPATMKYLGYFPALSPTEVEERVTLSRK 97
Query: 68 AFPGWKATPAIEKRDLFYKLAGLLERDIDILSKIESLDTGKPIANNAKYDILEVVEVLKY 127
A W + +R L + +++ ++ S DTGK + + + +I+ E + +
Sbjct: 98 AQKTWAQSSFKLRRQFLRILLKYIIEHQELICEVSSRDTGKTMVDASLGEIMTTCEKITW 157
Query: 128 YAG----WIDKAGGQSFAPSSEKLAYTLHQPLGVVGCIIPFNYPLA-MMSWKWTAIATGN 182
W+ S K++ PLGV+G I+P+NYP + + A+ +GN
Sbjct: 158 LLSEGERWLKPESRSSGRAMLHKVSRVEFHPLGVIGAIVPWNYPFHNIFNPMLAAVFSGN 217
Query: 183 TTVFKSADQTPLSILYFAKLVKEA----GFPAGVFNVLSGTGASVGSAIVKHTGVDKIAF 238
V K ++ S ++ ++++ A G P + +V++G A G A+V + VDK+ F
Sbjct: 218 GIVIKVSEHASWSGCFYFRIIQAALAAVGAPENLVDVITGF-AETGEALV--SSVDKMIF 274
Query: 239 TGSTAVGQIIQQQSAVNLKPITLECGGKSANMIFEDCDLEQAVKWSAWGIFNNMGQICSG 298
GSTAVG++I + +A L P+TLE GGK A +I ED D+ + + G + GQ C+G
Sbjct: 275 VGSTAVGKMIMRNAAETLTPVTLELGGKDAFIICEDADVSHVAQVAVRGTLQSSGQNCAG 334
Query: 299 TSRVFVQESIYEEFVAQLADHVKKTYIVGAPSDDAVIVGPQVSKKQQERVLEYIKIGIEE 358
R +V + IY F+ Q+ + K+ G P +G ++ E + + +++
Sbjct: 335 AERFYVHKDIYTAFIGQVT-KIVKSVSAGPPLTGRYDMGAICLQEHSEHLQSLVNDALDK 393
Query: 359 GCKVPL-GGLGAPEPIANDPALANGYYVKPTILADVKASYRIAKEEIFGPVIVVGSFKDY 417
G ++ + G G A D Y PT+L +V + +I KEE FGP++ + F
Sbjct: 394 GAEIAVRGSFGHLGEDAVD------QYFPPTVLINVNHNMKIMKEEAFGPIMPIMQFSTD 447
Query: 418 KEALDIANDSDYGLGSAIFSKDIVTCHKFAQDVEAGMVWIN--SSNDVDINVPFGGVKMS 475
+E + +ANDS Y LG A+FS + A ++ G+ IN +SN + ++PFGGVK S
Sbjct: 448 EEVIKLANDSRYALGCAVFSGSKHRAKQIASQIQCGVAAINDFASNYMCQSLPFGGVKDS 507
Query: 476 GHGRELGEYGLANFTNVKSVH 496
G GR G GL VKSV+
Sbjct: 508 GFGRFAGIEGLRACCLVKSVY 528
>CE01232 [C] KOG2453 Aldehyde dehydrogenase
Length = 514
Score = 200 bits (509), Expect = 4e-51
Identities = 147/510 (28%), Positives = 250/510 (48%), Gaps = 38/510 (7%)
Query: 14 YQQPLGLFINNEYVE----AHGSETLTSYNPSSGEEICKVQCADPKIDVDLAVKAARDAF 69
+ + LGL NN V A + + S+ P++ I VQ + + D ++A+ A+ A+
Sbjct: 14 FLKELGLTENNAGVFHGKWAASGQVVQSFAPANNSPIANVQNGNVQ-DYEIAISEAKKAY 72
Query: 70 PGWKATPAIEKRDLFYKLAGLLERDIDILSKIESLDTGKPIANNAKYDILEVVEVLKYYA 129
W PA + ++ ++ L + L K+ SL+ GK I+ ++ E V++ Y
Sbjct: 73 NDWCEVPAPRRGEIVRQIGDKLRTQLQNLGKLVSLEMGK-ISAEGVGEVQEYVDICDYAT 131
Query: 130 GWIDKAGGQSFAPSSEKLAYTLHQ---PLGVVGCIIPFNYPLAMMSWKWT-AIATGNTTV 185
G G+ F SE+ + L + PLGVVG I FN+P A+ W A+ TGN+ V
Sbjct: 132 GLSRSLEGKIFP--SERPGHALLEQWNPLGVVGVISAFNFPCAVYGWNNALALVTGNSVV 189
Query: 186 FKSADQTPLSILYFAKLVKEA----GFPAGVFNVLSGTGASVGSAIVKHTGVDKIAFTGS 241
+K A TPL+ + KLV+E + +++ G G VG A+VK V+ ++FTGS
Sbjct: 190 WKPAPSTPLTAIAVTKLVEEVLVANNVNPALCSLVCGEG-DVGQALVKDKRVNLVSFTGS 248
Query: 242 TAVGQIIQQQSAVNLKPITLECGGKSANMIFEDCDLEQAVKWSAWGIFNNMGQICSGTSR 301
+ +G+I+ QQ + LE GG +A ++ ED DL V + + GQ C+ T R
Sbjct: 249 SEIGKIVGQQVQARFGKLLLELGGNNAIIVNEDADLNMVVPATVFAAVGTAGQRCTTTRR 308
Query: 302 VFVQESIYEEFVAQLADHVKKTYI-----VGAPSDDAVIVGPQVSKKQQERVLEYIKIGI 356
+ V + +Y+ Q+ + +KK Y +G P D I+GP +++ + + +
Sbjct: 309 LIVHDKVYD----QVLERLKKAYAQFESRIGCPLDSNTIIGPLHNQQAVGKYKASVAEAV 364
Query: 357 EEGCKVPLGGLGAPEPIANDPALANGYYVKPTILADVKASYRIAKEEIFGPVIVVGSFKD 416
G K+ GG + + D G +V PTI+ +K + E F P++ V F
Sbjct: 365 ASGGKIEYGG----KVLERD-----GNFVLPTIVTGLKHDSPVVLRETFAPILYVLKFST 415
Query: 417 YKEALDIANDSDYGLGSAIFSKDIVTCHKF--AQDVEAGMVWIN-SSNDVDINVPFGGVK 473
+EA+ I N+ D GL S++F+ +I K+ + + G+V +N ++ +I FGG K
Sbjct: 416 LEEAIAINNEVDQGLSSSLFTTNIQNVFKWMGPKGSDCGIVNVNIPTSGAEIGGAFGGEK 475
Query: 474 MSGHGRELGEYGLANFTNVKSVHVNLGRKL 503
+G GRE G + + +N ++L
Sbjct: 476 ETGGGRESGSDSWRQYMRRSTCTINYSKEL 505
>Hs4557343 [C] KOG2453 Aldehyde dehydrogenase
Length = 511
Score = 191 bits (486), Expect = 2e-48
Identities = 153/505 (30%), Positives = 245/505 (48%), Gaps = 38/505 (7%)
Query: 18 LGLFINNEYVEAHGS-----ETLTSYNPSSGEEICKVQCADPKIDVDLAVKAARDAFPGW 72
LGL NE V +GS E +T+Y P++ E I +V+ A D + VK AR+A+ W
Sbjct: 17 LGLREENEGVY-NGSWGGRGEVITTYCPANNEPIARVRQASVA-DYEETVKKAREAWKIW 74
Query: 73 KATPAIEKRDLFYKLAGLLERDIDILSKIESLDTGKPIANNAKYDILEVVEVLKYYAGWI 132
PA ++ ++ ++ L I +L + SL+ GK + ++ E V++ Y G
Sbjct: 75 ADIPAPKRGEIVRQIGDALREKIQVLGSLVSLEMGKILVEGVG-EVQEYVDICDYAVGLS 133
Query: 133 DKAGGQSFAPSSEKLAYTLHQ---PLGVVGCIIPFNYPLAMMSWKWT-AIATGNTTVFKS 188
GG SE+ + L + P+G+VG I FN+P+A+ W A+ GN ++K
Sbjct: 134 RMIGGPILP--SERSGHALIEQWNPVGLVGIITAFNFPVAVYGWNNAIAMICGNVCLWKG 191
Query: 189 ADQTPLSIL----YFAKLVKEAGFPAGVFNVLSGTGASVGSAIVKHTGVDKIAFTGSTAV 244
A T L + AK++++ P + ++ G GA +G+A+ K V+ ++FTGST V
Sbjct: 192 APTTSLISVAVTKIIAKVLEDNKLPGAICSLTCG-GADIGTAMAKDERVNLLSFTGSTQV 250
Query: 245 GQIIQQQSAVNLKPITLECGGKSANMIFEDCDLEQAVKWSAWGIFNNMGQICSGTSRVFV 304
G+ + LE GG +A + FED DL V + + GQ C+ R+F+
Sbjct: 251 GKQVGLMVQERFGRSLLELGGNNAIIAFEDADLSLVVPSALFAAVGTAGQRCTTARRLFI 310
Query: 305 QESIYEEFVAQLADHVKKTYI---VGAPSDDAVIVGPQVSKKQQERVLEYIKIGIEEGCK 361
ESI++E V +L KK Y VG P D V+ GP +K+ L ++ +EG
Sbjct: 311 HESIHDEVVNRL----KKAYAQIRVGNPWDPNVLYGPLHTKQAVSMFLGAVEEAKKEGGT 366
Query: 362 VPLGGLGAPEPIANDPALANGYYVKPTILADVKASYRIAKEEIFGPVIVVGSFKDYKEAL 421
V GG P G YV+PTI+ + IA E F P++ V FK+ +E
Sbjct: 367 VVYGGKVMDRP---------GNYVEPTIVTGLGHDASIAHTETFAPILYVFKFKNEEEVF 417
Query: 422 DIANDSDYGLGSAIFSKDIVTCHKF--AQDVEAGMVWIN-SSNDVDINVPFGGVKMSGHG 478
N+ GL S+IF+KD+ ++ + + G+V +N ++ +I FGG K +G G
Sbjct: 418 AWNNEVKQGLSSSIFTKDLGRIFRWLGPKGSDCGIVNVNIPTSGAEIGGAFGGEKHTGGG 477
Query: 479 RELGEYGLANFTNVKSVHVNLGRKL 503
RE G + + +N + L
Sbjct: 478 RESGSDAWKQYMRRSTCTINYSKDL 502
>7293810 [C] KOG2453 Aldehyde dehydrogenase
Length = 594
Score = 182 bits (461), Expect = 1e-45
Identities = 142/515 (27%), Positives = 255/515 (48%), Gaps = 33/515 (6%)
Query: 2 SFTSIKLADGTEYQ--QPLGLFINNEYVEAHGSE----TLTSYNPSSGEEICKVQCADPK 55
S +S L D EY + LGL +N V + + ++TSY+P +G+ I KV+ + +
Sbjct: 79 SSSSSYLIDQPEYSFLKELGLERDNPGVYSGQWQGRGPSVTSYDPGTGQPIAKVRQGNVQ 138
Query: 56 IDVDLAVKAARDAFPGWKATPAIEKRDLFYKLAGLLERDIDILSKIESLDTGKPIANNAK 115
+++ + A +A+ W+ PA + ++ ++ L + + L K+ SL+ GK I + +
Sbjct: 139 -ELEHTIGLAVEAYKQWRQVPAPVRGEIVRQIGDELRKYKEPLGKLVSLEVGK-IYSEGQ 196
Query: 116 YDILEVVEVLKYYAGWIDKAGGQSFAPSSEKLAYTLHQ---PLGVVGCIIPFNYPLAMMS 172
++ E +++ Y G GQ +SE+ +++ + PLGVVG I +N+P A+
Sbjct: 197 GEVQEFIDICDYAVGLSRIYSGQLI--NSERADHSILEAWRPLGVVGVISAYNFPNAVFG 254
Query: 173 WKWT-AIATGNTTVFKSADQTPLSILYFAKLVKEA----GFPAGVFNVLSGTGASVGSAI 227
W A+ TGN+ ++K A TPL + K+V E P V L G VG +
Sbjct: 255 WNAAIALTTGNSVLWKGAPSTPLVSVATTKIVAEVLRRNNLPPVV--TLCQGGTDVGQTL 312
Query: 228 VKHTGVDKIAFTGSTAVGQIIQQQSAVNLKPITLECGGKSANMIFEDCDLEQAVKWSAWG 287
V V+ ++FTGS G+ + + + LE GG +A +I E +++ A+ + +G
Sbjct: 313 VADKRVNLVSFTGSCQTGRDVGVEVQRRFGKVILELGGNNALIIDESANVKMALDAALFG 372
Query: 288 IFNNMGQICSGTSRVFVQESIYEEFVAQLADHVKKTYI-VGAPSDDAVIVGPQVSKKQQE 346
GQ C+ T R+ V E ++++FV +L K+ +G + +VGP +++
Sbjct: 373 CIGTSGQRCTTTRRIIVHEKLHDQFVKELVGKYKQLISKIGHQLEAQTLVGPVHTQQN-- 430
Query: 347 RVLEYIKIGIEEGCKVPLGGLGAPEPIANDPALANGYYVKPTILADVKASYRIAKEEIFG 406
+E K I E LG + +G+YV+PT++ + + E F
Sbjct: 431 --VENYKAAIAEA-----KSLGGTVAFGGNVIQRDGFYVEPTVITGLPHDASVVHRETFA 483
Query: 407 PVIVVGSFKDYKEALDIANDSDYGLGSAIFSKDIVTCHKF--AQDVEAGMVWIN-SSNDV 463
P++ + K+ +A++ N+ + GL SAIF+++I K+ A+ + G+V IN ++N
Sbjct: 484 PIVYILKAKNVDQAIEWNNEVEQGLSSAIFTENIGQAFKWIGAKGSDCGIVNINTTTNGA 543
Query: 464 DINVPFGGVKMSGHGRELGEYGLANFTNVKSVHVN 498
+I FGG K +G GRE G + ++ VN
Sbjct: 544 EIGGAFGGEKATGGGRESGSDAWKQYCKRATITVN 578
>YHR039c [C] KOG1772 Vacuolar H+-ATPase V1 sector subunit G
Length = 644
Score = 165 bits (417), Expect = 2e-40
Identities = 123/464 (26%), Positives = 214/464 (45%), Gaps = 34/464 (7%)
Query: 57 DVDLAVKAARDAFPGWKATPAIEKRDLFYKLAGLLERDIDILSKIESLDTGKPIANNAKY 116
D+D V A A W + + + L + + D+++++ D+GK + + +
Sbjct: 133 DIDEMVSKAGKAQSTWGNSDFSRRLRVLASLHDYILNNQDLIARVACRDSGKTMLDASMG 192
Query: 117 DILEVVEVLKYYAGWIDKAGGQSFAPSSE-----------KLAYTLHQPLGVVGCIIPFN 165
+IL +E ++ W K G ++ PS K A ++PLGV+ I+ +N
Sbjct: 193 EILVTLEKIQ----WTIKHGQRALQPSRRPGPTNFFMKWYKGAEIRYEPLGVISSIVSWN 248
Query: 166 YPLA-MMSWKWTAIATGNTTVFKSADQTPLSILYFAKLVKEA--------GFPAGVFNVL 216
YP ++ A+ TGN V K ++Q S +F +L+++ + +
Sbjct: 249 YPFHNLLGPIIAALFTGNAIVVKCSEQVVWSSEFFVELIRKCLEACDEDPDLVQLCYCLP 308
Query: 217 SGTGASVGSAIVKHTGVDKIAFTGSTAVGQIIQQQSAVNLKPITLECGGKSANMIFEDC- 275
+ H G I F GS V I + +A +L P+ +E GGK A ++ +
Sbjct: 309 PTENDDSANYFTSHPGFKHITFIGSQPVAHYILKCAAKSLTPVVVELGGKDAFIVLDSAK 368
Query: 276 DLEQAVKWSAWGIFNNMGQICSGTSRVFVQESIYEEFVAQLADHVKKTYI-VGAPSD--D 332
+L+ G F + GQ C G RV V + Y++ V L D + + G+ D +
Sbjct: 369 NLDALSSIIMRGTFQSSGQNCIGIERVIVSKENYDDLVKILNDRMTANPLRQGSDIDHLE 428
Query: 333 AVIVGPQVSKKQQERVLEYIKIGIEEGCKVPLGGLGAPEPIANDPALANGYYVKPTILAD 392
V +G +S + + + +K + +G ++ GG P G+Y +PT+L D
Sbjct: 429 NVDMGAMISDNRFDELEALVKDAVAKGARLLQGGSRFKHP-----KYPQGHYFQPTLLVD 483
Query: 393 VKASYRIAKEEIFGPVIVVGSFKDYKEALDIANDSDYGLGSAIFSKDIVTCHKFAQDVEA 452
V +IA+ E+FGP++V+ K+ + +AN + +GLG ++F DI C+ A ++
Sbjct: 484 VTPEMKIAQNEVFGPILVMMKAKNTDHCVQLANSAPFGLGGSVFGADIKECNYVANSLQT 543
Query: 453 GMVWINSSNDVDI-NVPFGGVKMSGHGRELGEYGLANFTNVKSV 495
G V IN + +PFGG+ SG+G+ GE GL N KSV
Sbjct: 544 GNVAINDFATFYVCQLPFGGINGSGYGKFGGEEGLLGLCNAKSV 587
>At2g24270 [C] KOG2450 Aldehyde dehydrogenase
Length = 496
Score = 164 bits (414), Expect = 4e-40
Identities = 146/508 (28%), Positives = 242/508 (46%), Gaps = 43/508 (8%)
Query: 7 KLADGTEYQQPLGLFINNEYVEAHGSETLTSYNPSSGEEICKVQCADPKIDVDLAVKAAR 66
++ DG Y+ + + E+ + +++ NP++ + KVQ + +V+ ++ A+
Sbjct: 9 EILDGEVYKY----YADGEWKTSSSGKSVAIMNPATRKTQYKVQACTQE-EVNAVMELAK 63
Query: 67 DAFPGWKATPAIEKRDLFYKLAGLLERDIDILSKIESLDTGKPIANNAKYDILEVV---E 123
A W TP ++ +L +K A +L+ + ++ ESL K IA AK + EVV +
Sbjct: 64 SAQKSWAKTPLWKRAELLHKAAAILKDNKAPMA--ESLV--KEIAKPAKDSVTEVVRSGD 119
Query: 124 VLKYYAGWIDKAGGQ-------SFAPSSEKLAYTLHQ--PLGVVGCIIPFNYPLAMMSWK 174
++ Y A + G+ SF P +++ Y L PLGVV I PFNYP+ + K
Sbjct: 120 LISYCAEEGVRILGEGKFLLSDSF-PGNDRTKYCLTSKIPLGVVLAIPPFNYPVNLAVSK 178
Query: 175 WT-AIATGNTTVFKSADQTPLSILYFAKLVKEAGFPAGVFNVLSGTGASVGSAIVKHTGV 233
A+ GN+ V K Q +S L+ AGFP G+ + ++G G+ +G + H V
Sbjct: 179 IAPALIAGNSLVLKPPTQGAVSCLHMVHCFHLAGFPKGLISCITGKGSEIGDFLTMHPAV 238
Query: 234 DKIAFTGSTAVGQIIQQQSAVNLKPITLECGGKSANMIFEDCDLEQAVKWSAWGIFNNMG 293
+ I+FTG I ++ + P+ +E GGK A ++ +D DL+ G F+ G
Sbjct: 239 NCISFTGGDTGISISKKAGMI---PLQMELGGKDACIVLDDADLDLVASNIIKGGFSYSG 295
Query: 294 QICSGTSRVFVQESIYEEFVAQLADHVKKTYIVGAPSDDAVIVGPQVSKKQQERVLEYIK 353
Q C+ V V ES+ +E V ++ V K VG P +++ I V + +E +
Sbjct: 296 QRCTAVKVVLVMESVADELVEKVKAKVAKL-TVGPPEENSDITA--VVSESSANFIEGLV 352
Query: 354 IGIEEGCKVPLGGLGAPEPIANDPALANGYYVKPTILADVKASYRIAKEEIFGPVIVVGS 413
+ +E G E G + P +L +V+ RIA EE FGPV+ V
Sbjct: 353 MDAKEK-----GATFCQE------YKREGNLIWPLLLDNVRPDMRIAWEEPFGPVVPVLR 401
Query: 414 FKDYKEALDIANDSDYGLGSAIFSKDIVTCHKFAQDVEAGMVWINS--SNDVDINVPFGG 471
+E ++ N S++GL +F+KDI + +E G V INS + D + PF G
Sbjct: 402 INSVEEGINHCNASNFGLQGCVFTKDINKAILISDAMETGTVQINSAPARGPD-HFPFQG 460
Query: 472 VKMSGHGRELGEYGLANFTNVKSVHVNL 499
+K SG G + + T VK+ +NL
Sbjct: 461 LKDSGIGSQGVTNSINLMTKVKTTVINL 488
>HsM4502035 [C] KOG2456 Aldehyde dehydrogenase
Length = 453
Score = 152 bits (384), Expect = 1e-36
Identities = 129/444 (29%), Positives = 203/444 (45%), Gaps = 33/444 (7%)
Query: 61 AVKAARDAFPGWKATPAIEKRDLFYKLAGLLERDIDILSKIESLDTGKPIANNAKYDILE 120
AVK AR AF + P + L L++ L + D K N +++
Sbjct: 7 AVKRARAAFSSGRTRPLQFRFQQLEALQRLIQEQEQELVGALAADLHKNEWNAYYEEVVY 66
Query: 121 VVEVLKYYAG----WIDKAGGQSFAPSSEKLAYTLHQPLGVVGCIIPFNYPLAMMSWKWT 176
V+E ++Y W + + + Y +PLGVV I +NYP +
Sbjct: 67 VLEEIEYMIQKLPEWAADEPVEKTPQTQQDELYIHSEPLGVVLVIGTWNYPFNLTIQPMV 126
Query: 177 -AIATGNTTVFKSADQTPLSILYFAKLVKEAGFPAGVFNVLSGTGASVGSAIVKHTGVDK 235
AIA GN V K ++ + A ++ + ++ V++G G + ++K D
Sbjct: 127 GAIAAGNAVVLKPSELSENMASLLATIIPQY-LDKDLYPVING-GVPETTELLKER-FDH 183
Query: 236 IAFTGSTAVGQIIQQQSAVNLKPITLECGGKSANMIFEDCDLEQAVKWSAWGIFNNMGQI 295
I +TGST VG+II +A +L P+TLE GGKS + ++CDL+ A + AWG F N GQ
Sbjct: 184 ILYTGSTGVGKIIMTAAAKHLTPVTLELGGKSPCYVDKNCDLDVACRRIAWGKFMNSGQT 243
Query: 296 CSGTSRVFVQESIYEEFVAQLADHVKKTYIVGAPSDDAVIVGPQVSKKQQERVLEYIKIG 355
C + SI + V +L +K+ Y G + + G +S + +RV+ G
Sbjct: 244 CVAPDYILCDPSIQNQIVEKLKKSLKEFY--GEDAKKSRDYGRIISARHFQRVM-----G 296
Query: 356 IEEGCKVPLGGLGAPEPIANDPALANGYYVKPTILADVKASYRIAKEEIFGPVIVVGSFK 415
+ EG KV GG G A Y+ PTIL DV + +EEIFGPV+ + +
Sbjct: 297 LIEGQKVAYGGTGD----------AATRYIAPTILTDVDPQSPVMQEEIFGPVLPIVCVR 346
Query: 416 DYKEALDIANDSDYGLGSAIFSKDIVTCHKFAQDVEAGMVWINSSNDVDINV-----PFG 470
+EA+ N + L +FS + K + +G V ++NDV +++ PFG
Sbjct: 347 SLEEAIQFINQREKPLALYMFSSNDKVIKKMIAETSSGGV---AANDVIVHITLHSLPFG 403
Query: 471 GVKMSGHGRELGEYGLANFTNVKS 494
GV SG G G+ F++ +S
Sbjct: 404 GVGNSGMGSYHGKKSFETFSHRRS 427
>Hs21359829 [C] KOG2456 Aldehyde dehydrogenase
Length = 453
Score = 152 bits (384), Expect = 1e-36
Identities = 129/444 (29%), Positives = 203/444 (45%), Gaps = 33/444 (7%)
Query: 61 AVKAARDAFPGWKATPAIEKRDLFYKLAGLLERDIDILSKIESLDTGKPIANNAKYDILE 120
AVK AR AF + P + L L++ L + D K N +++
Sbjct: 7 AVKRARAAFSSGRTRPLQFRIQQLEALQRLIQEQEQELVGALAADLHKNEWNAYYEEVVY 66
Query: 121 VVEVLKYYAG----WIDKAGGQSFAPSSEKLAYTLHQPLGVVGCIIPFNYPLAMMSWKWT 176
V+E ++Y W + + + Y +PLGVV I +NYP +
Sbjct: 67 VLEEIEYMIQKLPEWAADEPVEKTPQTQQDELYIHSEPLGVVLVIGTWNYPFNLTIQPMV 126
Query: 177 -AIATGNTTVFKSADQTPLSILYFAKLVKEAGFPAGVFNVLSGTGASVGSAIVKHTGVDK 235
AIA GN V K ++ + A ++ + ++ V++G G + ++K D
Sbjct: 127 GAIAAGNAVVLKPSELSENMASLLATIIPQY-LDKDLYPVING-GVPETTELLKER-FDH 183
Query: 236 IAFTGSTAVGQIIQQQSAVNLKPITLECGGKSANMIFEDCDLEQAVKWSAWGIFNNMGQI 295
I +TGST VG+II +A +L P+TLE GGKS + ++CDL+ A + AWG F N GQ
Sbjct: 184 ILYTGSTGVGKIIMTAAAKHLTPVTLELGGKSPCYVDKNCDLDVACRRIAWGKFMNSGQT 243
Query: 296 CSGTSRVFVQESIYEEFVAQLADHVKKTYIVGAPSDDAVIVGPQVSKKQQERVLEYIKIG 355
C + SI + V +L +K+ Y G + + G +S + +RV+ G
Sbjct: 244 CVAPDYILCDPSIQNQIVEKLKKSLKEFY--GEDAKKSRDYGRIISARHFQRVM-----G 296
Query: 356 IEEGCKVPLGGLGAPEPIANDPALANGYYVKPTILADVKASYRIAKEEIFGPVIVVGSFK 415
+ EG KV GG G A Y+ PTIL DV + +EEIFGPV+ + +
Sbjct: 297 LIEGQKVAYGGTGD----------AATRYIAPTILTDVDPQSPVMQEEIFGPVLPIVCVR 346
Query: 416 DYKEALDIANDSDYGLGSAIFSKDIVTCHKFAQDVEAGMVWINSSNDVDINV-----PFG 470
+EA+ N + L +FS + K + +G V ++NDV +++ PFG
Sbjct: 347 SLEEAIQFINQREKPLALYMFSSNDKVIKKMIAETSSGGV---AANDVIVHITLHSLPFG 403
Query: 471 GVKMSGHGRELGEYGLANFTNVKS 494
GV SG G G+ F++ +S
Sbjct: 404 GVGNSGMGSYHGKKSFETFSHRRS 427
>Hs4557303 [C] KOG2456 Aldehyde dehydrogenase
Length = 485
Score = 147 bits (371), Expect = 4e-35
Identities = 125/448 (27%), Positives = 215/448 (47%), Gaps = 41/448 (9%)
Query: 58 VDLAVKAARDAFPGWKATPAIEKRDLFYKLAGLL-ERDIDILSKIESLDTGKPIANNAKY 116
++L V+ R AF ++ P + L ++ ER+ DIL+ I + D K N
Sbjct: 1 MELEVRRVRQAFLSGRSRPLRFRLQQLEALRRMVQEREKDILTAIAA-DLCKSEFNVYSQ 59
Query: 117 DILEVVE----VLKYYAGWIDKAGGQSFAPSSEKLAYTLHQPLGVVGCIIPFNYPLAMMS 172
+++ V+ +L+ W+ + + AY QPLGVV I +NYP +
Sbjct: 60 EVITVLGEIDFMLENLPEWVTAKPVKKNVLTMLDEAYIQPQPLGVVLIIGAWNYPFVLTI 119
Query: 173 WKWT-AIATGNTTVFKSADQTPLSILYFAKLVKEAGFPAGVFNVLSGTGASVGSAIVKHT 231
AIA GN + K ++ + + AKL+ + ++ V++G G + ++K
Sbjct: 120 QPLIGAIAAGNAVIIKPSELSENTAKILAKLLPQY-LDQDLYIVING-GVEETTELLKQR 177
Query: 232 GVDKIAFTGSTAVGQIIQQQSAVNLKPITLECGGKSANMIFEDCDLEQAVKWSAWGIFNN 291
D I +TG+TAVG+I+ + +A +L P+TLE GGKS I +DCDL+ + WG + N
Sbjct: 178 -FDHIFYTGNTAVGKIVMEAAAKHLTPVTLELGGKSPCYIDKDCDLDIVCRRITWGKYMN 236
Query: 292 MGQICSGTSRVFVQESIYEEFVAQLADHVKKTY---IVGAPSDDAVIVGPQVSKKQQERV 348
GQ C + + S+ + V ++ + VK+ Y I +P + +I + + +R+
Sbjct: 237 CGQTCIAPDYILCEASLQNQIVWKIKETVKEFYGENIKESPDYERII-----NLRHFKRI 291
Query: 349 LEYIKIGIEEGCKVPLGGLGAPEPIANDPALANGYYVKPTILADVKASYRIAKEEIFGPV 408
L + EG K+ GG D A Y+ PT+L DV ++ +EEIFGP+
Sbjct: 292 LSLL-----EGQKIAFGG-------ETDEATR---YIAPTVLTDVDPKTKVMQEEIFGPI 336
Query: 409 IVVGSFKDYKEALDIANDSDYGLGSAIFSKDIVTCHKFAQDVEAGMVWINSSNDVDI--- 465
+ + K+ EA++ N+ + L +FS + + + +G V + NDV +
Sbjct: 337 LPIVPVKNVDEAINFINEREKPLALYVFSHNHKLIKRMIDETSSGGV---TGNDVIMHFT 393
Query: 466 --NVPFGGVKMSGHGRELGEYGLANFTN 491
+ PFGGV SG G G++ F++
Sbjct: 394 LNSFPFGGVGSSGMGAYHGKHSFDTFSH 421
>Hs18603595 [C] KOG2456 Aldehyde dehydrogenase
Length = 508
Score = 147 bits (371), Expect = 4e-35
Identities = 125/448 (27%), Positives = 215/448 (47%), Gaps = 41/448 (9%)
Query: 58 VDLAVKAARDAFPGWKATPAIEKRDLFYKLAGLL-ERDIDILSKIESLDTGKPIANNAKY 116
++L V+ R AF ++ P + L ++ ER+ DIL+ I + D K N
Sbjct: 1 MELEVRRVRQAFLSGRSRPLRFRLQQLEALRRMVQEREKDILTAIAA-DLCKSEFNVYSQ 59
Query: 117 DILEVVE----VLKYYAGWIDKAGGQSFAPSSEKLAYTLHQPLGVVGCIIPFNYPLAMMS 172
+++ V+ +L+ W+ + + AY QPLGVV I +NYP +
Sbjct: 60 EVITVLGEIDFMLENLPEWVTAKPVKKNVLTMLDEAYIQPQPLGVVLIIGAWNYPFVLTI 119
Query: 173 WKWT-AIATGNTTVFKSADQTPLSILYFAKLVKEAGFPAGVFNVLSGTGASVGSAIVKHT 231
AIA GN + K ++ + + AKL+ + ++ V++G G + ++K
Sbjct: 120 QPLIGAIAAGNAVIIKPSELSENTAKILAKLLPQY-LDQDLYIVING-GVEETTELLKQR 177
Query: 232 GVDKIAFTGSTAVGQIIQQQSAVNLKPITLECGGKSANMIFEDCDLEQAVKWSAWGIFNN 291
D I +TG+TAVG+I+ + +A +L P+TLE GGKS I +DCDL+ + WG + N
Sbjct: 178 -FDHIFYTGNTAVGKIVMEAAAKHLTPVTLELGGKSPCYIDKDCDLDIVCRRITWGKYMN 236
Query: 292 MGQICSGTSRVFVQESIYEEFVAQLADHVKKTY---IVGAPSDDAVIVGPQVSKKQQERV 348
GQ C + + S+ + V ++ + VK+ Y I +P + +I + + +R+
Sbjct: 237 CGQTCIAPDYILCEASLQNQIVWKIKETVKEFYGENIKESPDYERII-----NLRHFKRI 291
Query: 349 LEYIKIGIEEGCKVPLGGLGAPEPIANDPALANGYYVKPTILADVKASYRIAKEEIFGPV 408
L + EG K+ GG D A Y+ PT+L DV ++ +EEIFGP+
Sbjct: 292 LSLL-----EGQKIAFGG-------ETDEATR---YIAPTVLTDVDPKTKVMQEEIFGPI 336
Query: 409 IVVGSFKDYKEALDIANDSDYGLGSAIFSKDIVTCHKFAQDVEAGMVWINSSNDVDI--- 465
+ + K+ EA++ N+ + L +FS + + + +G V + NDV +
Sbjct: 337 LPIVPVKNVDEAINFINEREKPLALYVFSHNHKLIKRMIDETSSGGV---TGNDVIMHFT 393
Query: 466 --NVPFGGVKMSGHGRELGEYGLANFTN 491
+ PFGGV SG G G++ F++
Sbjct: 394 LNSFPFGGVGSSGMGAYHGKHSFDTFSH 421
>CE13415 [C] KOG2456 Aldehyde dehydrogenase
Length = 437
Score = 142 bits (358), Expect = 1e-33
Identities = 123/442 (27%), Positives = 211/442 (46%), Gaps = 25/442 (5%)
Query: 62 VKAARDAFPGWKATPAIEKRDLFYKLAGLLERDIDILSKIESLDTGKPIANNAKYDILEV 121
V+A R F PA +++ +L L+E + L+++ D + ++
Sbjct: 7 VEAQRAYFNTGATKPAEFRKEQLLQLKKLIEENRAALTEVVWKDLRRRHEVTEPMELGGS 66
Query: 122 VEVLKYYAGWIDKAGGQSFA-PSSEKLA----YTLHQPLGVVGCIIPFNYPLAMMSWKWT 176
+E + YY +D ++ P+ L Y + P GVV I P+NYP++M+
Sbjct: 67 LEEIAYYLKNLDDWMKPTYVEPTVATLPTDKPYIVKDPKGVVLVISPWNYPVSMVLLPMI 126
Query: 177 -AIATGNTTVFKSADQTPLSILYFAKLVKEAGFPAGVFNVLSGTGASVGSAIVKHTGVDK 235
+IA GNT V K ++ + + + F KL+ + P V +++G G + ++K D
Sbjct: 127 PSIAAGNTIVIKPSELSENTAILFEKLIPKYFDPKYV-TIVNG-GIPETTELLKER-FDH 183
Query: 236 IAFTGSTAVGQIIQQQSAVNLKPITLECGGKSANMIFEDCDLEQAVKWSAWGIFNNMGQI 295
I +TG V +II +A +L P+TLE GGK ++ +D D+E + + A G + N GQ
Sbjct: 184 IIYTGCPPVAKIIMAAAAKHLTPVTLELGGKCPVVVEDDADIEISAQRIARGKWLNCGQT 243
Query: 296 CSGTSRVFVQESIYEEFVAQLADHVKKTYIVGAPSDDAVIVGPQVSKKQQERVLEYIKIG 355
C + V + +FVA + +K+ Y A S+ +R + I
Sbjct: 244 CLAPDYILVSSATKPKFVAAIQKCLKEFYGGNAKE------SKDYSRVINQRHFDRISAL 297
Query: 356 IEEGCKVPLGGLGAPEPIANDPALANGYYVKPTILADVKASYRIAKEEIFGPVIVVGSFK 415
++E V L G + + ++ PT+L DV+ + +EIFGPV+ + + K
Sbjct: 298 LDESKGVVLAG-------NEESRDRSDRFIPPTVL-DVEKTDPFMHDEIFGPVLPIITVK 349
Query: 416 DYKEALDIANDSDYGLGSAIFSKDIVTCHKFAQDVEAGMVWINS--SNDVDINVPFGGVK 473
+ E++D N + L + IF+KD +F + +G V +N + I +PFGGV
Sbjct: 350 NLCESIDFINKGEKPLAAYIFTKDEAKVQRFLNETTSGGVTVNDVIMHVAVITLPFGGVG 409
Query: 474 MSGHGRELGEYGLANFTNVKSV 495
+SG GR G++G FT+ KSV
Sbjct: 410 VSGMGRYRGKFGFDTFTHEKSV 431
>Hs4502037 [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrogenase
Length = 563
Score = 136 bits (343), Expect = 6e-32
Identities = 123/480 (25%), Positives = 208/480 (42%), Gaps = 34/480 (7%)
Query: 43 GEEICKVQCADPKIDVDLAVKAARDAFPGWKATPAIEKRDLFYKLAGLLE--RDIDILSK 100
G ++ K AD + ++ A++AA A W P ++ +F K A +L R +IL+K
Sbjct: 88 GHKVAKFCYADKSL-LNKAIEAALAARKEWDLKPIADRAQIFLKAADMLSGPRRAEILAK 146
Query: 101 IESLDTGKPIANNAKYDILEVVEVLKYYAGWIDKAGGQ---SFAPSSEKLAYTLHQPLGV 157
+ GK + E+++ ++ A + + GQ S PS+ Y + G
Sbjct: 147 T-MVGQGKTVIQAEIDAAAELIDFFRFNAKYAVELEGQQPISVPPSTNSTVYRGLE--GF 203
Query: 158 VGCIIPFNYPLAMMSWKWTAIATGNTTVFKSADQTPLSILYFAKLVKEAGFPAGVFNVLS 217
V I PFN+ + GN ++K +D L+ ++++EAG P + +
Sbjct: 204 VAAISPFNFTAIGGNLAGAPALMGNVVLWKPSDTAMLASYAVYRILREAGLPPNIIQFVP 263
Query: 218 GTGASVGSAIVKHTGVDKIAFTGSTAVGQIIQQQSAVNLKP------ITLECGGKSANMI 271
G G + + I FTGS + + +Q A NL + ECGGK+ + +
Sbjct: 264 ADGPLFGDTVTSSEHLCGINFTGSVPTFKHLWKQVAQNLDRFHTFPRLAGECGGKNFHFV 323
Query: 272 FEDCDLEQAVKWSAWGIFNNMGQICSGTSRVFVQESIYEEFVAQLADHVKKTYIVGAPSD 331
D+E V + F GQ CS SR++V S++ + +L + + + D
Sbjct: 324 HRSADVESVVSGTLRSAFEYGGQKCSACSRLYVPHSLWPQIKGRLLEEHSRIKVGDPAED 383
Query: 332 DAVIVGPQVSKKQQERVLEYIKIGIEEGCKVPLGGLGAPEPIANDPALANGYYVKPTILA 391
+ K R+ ++++ L G + + GY+V+P I+
Sbjct: 384 FGTFFSAVIDAKSFARIKKWLEHARSSPSLTILAGGKCDDSV--------GYFVEPCIVE 435
Query: 392 DVKASYRIAKEEIFGPVIVVGSFKD--YKEALDIAND-SDYGLGSAIFS--KDIVTCHKF 446
I KEEIFGPV+ V + D YKE L + + + YGL A+FS KD+V
Sbjct: 436 SKDPQEPIMKEEIFGPVLSVYVYPDDKYKETLQLVDSTTSYGLTGAVFSQDKDVVQEATK 495
Query: 447 AQDVEAGMVWIN--SSNDVDINVPFGGVKMSG-HGRELGEYGLANFTN---VKSVHVNLG 500
AG +IN S+ + PFGG + SG + + G + + +T+ +K H LG
Sbjct: 496 VLRNAAGNFYINDKSTGSIVGQQPFGGARASGTNDKPGGPHYILRWTSPQVIKETHKPLG 555
>CE27441 [C] KOG2456 Aldehyde dehydrogenase
Length = 493
Score = 136 bits (342), Expect = 8e-32
Identities = 118/444 (26%), Positives = 207/444 (46%), Gaps = 32/444 (7%)
Query: 62 VKAARDAFPGWKATPAIEKRDLFYKLAGLLERDIDILSKIESLDTGKPIANNAKYDILEV 121
V+ R F + P ++ KL +E + + LS+ D + + +I
Sbjct: 7 VETQRKYFRTGETKPVKFRKQQLLKLKKFIEENREALSEAVWKDLRRRHESTEILEIGMT 66
Query: 122 VEVLKYYA----GWIDKAGGQSFAPSSEKLAYTLHQPLGVVGCIIPFNYPLAMMSWKWT- 176
++ + Y+ W+ + ++ P GVV I P+NYP++M+
Sbjct: 67 IQEIDYFLKNIDDWVKPTHVEKTFTTALDKPVIEKDPKGVVLIISPWNYPVSMILLPMVP 126
Query: 177 AIATGNTTVFKSADQTPLSILYFAKLVKEAGFPAGVFNVLSGTGASVGSAIVKHTGVDKI 236
AIA GNT V K ++ + F KL+ + F + V++G G + ++K D I
Sbjct: 127 AIAAGNTVVIKPSELSENVAATFEKLIPKY-FESKYVTVVNG-GIPETTDLLKER-FDHI 183
Query: 237 AFTGSTAVGQIIQQQSAVNLKPITLECGGKSANMIFEDCDLEQAVKWSAWGIFNNMGQIC 296
+TG V +II +A +L P+TLE GGK ++ +D D++ + K AWG + N GQ C
Sbjct: 184 LYTGCPPVAKIIMTAAAKHLTPVTLELGGKCPVVVEDDADIDISAKRIAWGKWLNCGQTC 243
Query: 297 SGTSRVFVQESIYEEFVAQLADHVKKTYIVGAPSDDAVIVGPQVSKKQQERVLEYIKIGI 356
+ V ++ + VA + +V + Y G + ++++ +R+ +
Sbjct: 244 LAPDYILVNSTVKPKLVAAIRKYVNEFY--GEDVKASKDYARMINQRHFDRISGLLD--- 298
Query: 357 EEGCKVPLGGLGAPEPIANDPALANGYYVKPTILADVKASYRIAKEEIFGPVIVVGSFKD 416
+ V +GG D A Y+ PT+L DV+ S +EIFGPV+ + + +
Sbjct: 299 KTQGAVLIGG-------ERDRA---DLYIPPTVL-DVEKSDPFMHDEIFGPVLPIITVQS 347
Query: 417 YKEALDIANDSDYGLGSAIFSKDIVTCHKFAQDVEAGMVWINSSNDVDINV-----PFGG 471
+ E+L+ D + L + IF+++ + + +G V + NDV +++ PFGG
Sbjct: 348 FSESLEYIADGEKPLAAYIFTRNEAKVKRLLNETSSGGVTV---NDVLMHITVDTLPFGG 404
Query: 472 VKMSGHGRELGEYGLANFTNVKSV 495
V +SG GR G+YG FT+ KSV
Sbjct: 405 VGVSGMGRYRGKYGFDTFTHEKSV 428
>7296504 [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrogenase
Length = 574
Score = 135 bits (339), Expect = 2e-31
Identities = 121/468 (25%), Positives = 208/468 (43%), Gaps = 40/468 (8%)
Query: 52 ADPKIDVDLAVKAARDAFPGWKATPAIEKRDLFYKLAGLL----ERDIDILSKIESLDTG 107
AD K+ ++ A+K A + P W ++ ++ K A L+ +D++ + + T
Sbjct: 106 ADKKL-IEKAIKTAVETQPKWDRVSIADRLKIWEKAADLMATTYRQDLNAATMLGQSKTA 164
Query: 108 KPIANNAKYDILEVVEVLKYYAGWIDKAGGQSFAPSSEKLAYTLHQPL-----GVVGCII 162
++ ++++ + + Y+ + K + P SE + T + G + +
Sbjct: 165 IQAEIDSAAELIDFIRMNAYFLKEVTK-----YQPISENIKVTKNSLRYRGIDGFIAAVS 219
Query: 163 PFNYPLAMMSWKWTAIATGNTTVFKSADQTPLSILYFAKLVKEAGFPAGVFNVLSGTGAS 222
PFN+ + +T GN ++K +D LS K+++EAG P GV N + G
Sbjct: 220 PFNFTAIGGNLSYTPALMGNGVLWKPSDTAMLSNWIIFKIMREAGVPDGVVNFVPADGPV 279
Query: 223 VGSAIVKHTGVDKIAFTGSTAVGQIIQQQ------SAVNLKPITLECGGKSANMIFEDCD 276
G I + I FTGS + +Q + VN +T ECGGK+ + I D
Sbjct: 280 FGDTITASPHLAGINFTGSVPTFNRLWKQVGNNIDNYVNFPRLTGECGGKNFHFIHASAD 339
Query: 277 LEQAVKWSAWGIFNNMGQICSGTSRVFVQESIYEEFVAQLADHVKKTYIVGAPSDDAVIV 336
+E V + F GQ CS SR++V ES++ + L K I G D +
Sbjct: 340 VESVVTSTIRSAFEYCGQKCSACSRMYVPESLWPQIKEGLVCEAAKLKI-GDVQDFSSFT 398
Query: 337 GPQVSKKQQERVLEYIKIGIEE-GCKVPLGGLGAPEPIANDPALANGYYVKPTILADVKA 395
+ K +R+ YI+ + ++ GG + + GY+V PTI+
Sbjct: 399 SAVIDDKAFKRITGYIEHAKKSPNLEILAGGTYSD---------SKGYFVNPTIVLSKDP 449
Query: 396 SYRIAKEEIFGPVIVVGSFK--DYKEALDIANDS-DYGLGSAIF--SKDIVTCHKFAQDV 450
RI EEIFGPV+ + +K D E + + + S + L A+F +D V C +
Sbjct: 450 KDRIMTEEIFGPVLSIYVYKESDLLETMKLVHTSTKFALTGAVFGQDEDFVKCALQEFKM 509
Query: 451 EAGMVWIN--SSNDVDINVPFGGVKMSG-HGRELGEYGLANFTNVKSV 495
AG +IN S+ V PFGG +MSG + + G + + +T+ +S+
Sbjct: 510 AAGNFYINDKSTGSVVGQQPFGGGRMSGTNDKAGGPHYILRWTSPQSI 557
>CE29047 [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrogenase
Length = 563
Score = 129 bits (324), Expect = 1e-29
Identities = 125/476 (26%), Positives = 215/476 (44%), Gaps = 49/476 (10%)
Query: 34 TLTSYNPSSGEEICKVQCADPKIDVDLAVKAARDAFPGWKATPAIEKRDLFYKLAGLLER 93
TL Y ++GE+I + IDV L + A W+ P E+ ++ + A L
Sbjct: 90 TLAKYTYATGEQIQEA------IDVALQARGA------WERKPLKERAEILLRAADLAAG 137
Query: 94 DIDI-LSKIESLDTGKPIANNAKYDILEVVEVLKYYAGWIDKAGGQSFAPSSEKLAYTLH 152
+ L+ L GK I E+++ ++ A + + + + P S K+
Sbjct: 138 KYRMKLNASTMLGQGKNIIQAEIDAACELIDFFRFNAVFAMEL--EHYEPISTKITKNTM 195
Query: 153 QPLGVVG---CIIPFNYPLAMMSWKWTAIATGNTTVFKSADQTPLSILYFAKLVKEAGFP 209
Q G+ G I PFN+ + GN +++K ++ LS +L++EAG P
Sbjct: 196 QFRGMEGFVAAIAPFNFTAIGGNLPTAPALMGNVSLWKPSNTAVLSNYIIYELLEEAGMP 255
Query: 210 AGVFNVLSGTGASVGSAIVKHTGVDKIAFTGSTAVGQIIQQQSAVNL------KPITLEC 263
G+ + L G G I + + FTGS + I ++ A NL + EC
Sbjct: 256 PGILSFLPSDGPVFGDVITASPHLSAVNFTGSVPTFKTIWRKVAENLDNYVTFPKLIGEC 315
Query: 264 GGKSANMIFEDCDLEQAVKWSAWGIFNNMGQICSGTSRVFVQESIYEEFVAQLADHVKKT 323
GGK+ + + ++ +A + GQ CS SR++ +SI+ + + +++ + K
Sbjct: 316 GGKNFHFVHPSAHVDAVAAGTARSAWEYSGQKCSACSRMYAPKSIWPKILEKIS-AIHKE 374
Query: 324 YIVGAPSDDAVIVGPQVSKKQQERVLEYI---KIGIEEGCKVPLGGLGAPEPIANDPALA 380
+G D +V + + K R+ YI K G +G V LGG +D
Sbjct: 375 IKLGDVRDGSVFLSAVIDDKAFARLKAYIDFAKTG-ADGANVVLGGK------CDD---K 424
Query: 381 NGYYVKPTILADVKASYRIAKEEIFGPVIVVGSFKDYK--EALDIAND-SDYGLGSAIFS 437
GY+++PT++ ++ EE+FGPV+ V ++D K E L D + YGL A+FS
Sbjct: 425 TGYFIEPTLITVTDPKSKLLTEEMFGPVVTVLVYEDSKVDEVLATVKDATPYGLTGAVFS 484
Query: 438 KDIVTCHKFAQDV---EAGMVWIN--SSNDVDINVPFGGVKMSGHGRELG--EYGL 486
+D ++ A+DV G +++N S+ + PFGG ++SG + G YGL
Sbjct: 485 QDKEFLYR-ARDVLRDAVGNMYLNDKSTGSIVGQQPFGGSRLSGTNDKAGGPHYGL 539
>YHR037w [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrogenase
Length = 575
Score = 127 bits (319), Expect = 4e-29
Identities = 131/512 (25%), Positives = 226/512 (43%), Gaps = 46/512 (8%)
Query: 20 LFINNEYVEAHGSETL-TSYNPSSGEEICKVQCADPKIDVDLAVKAARDAFPGWKATPAI 78
L IN E + + L NP++ +++ + DV AVKAA+DA W P
Sbjct: 63 LVINGERIYDNNERALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDAKKDWYNLPFY 122
Query: 79 EKRDLFYKLAGLLERDI--DILSKIESLDTGKPIANNAKYDILEVVEVLKYYAGWIDKAG 136
++ +F K A L+ D+L+ L GK + I E+ + +YY +
Sbjct: 123 DRSAIFLKAADLISTKYRYDMLAAT-MLGQGKNVYQAEIDCITELSDFFRYYVKYASDLY 181
Query: 137 GQSFAPSSE----KLAYTLHQPL-GVVGCIIPFNYPLAMMSWKWTAIATGNTTVFKSADQ 191
Q S++ K Y +PL G V + PFN+ + GNT V+K +
Sbjct: 182 AQQPVESADGTWNKAEY---RPLEGFVYAVSPFNFTAIAANLIGAPALMGNTVVWKPSQT 238
Query: 192 TPLSILYFAKLVKEAGFPAGVFNVLSGTGASVGSAIVKHTGVDKIAFTGSTAVGQII--Q 249
LS +++EAG P GV N + G V ++ + FTGST V + + +
Sbjct: 239 AALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGALHFTGSTNVFKSLYGK 298
Query: 250 QQSAV------NLKPITLECGGKSANMIFEDCDLEQAVKWSAWGIFNNMGQICSGTSRVF 303
QS V + I E GGK+ +++ ++ AV + G F GQ CS SR++
Sbjct: 299 IQSGVVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQKCSAASRLY 358
Query: 304 VQESIYEEFVAQLADHVKKTYIVGAPSDDAVI--------VGPQVSKKQQERVLEYIKIG 355
+ ES EEF++ + ++ +V + + I +GP + ++ +++++ I+
Sbjct: 359 LPESKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQSFDKLVKVIEDA 418
Query: 356 IEE-GCKVPLGGLGAPEPIANDPALANGYYVKPTILADVKASYRIAKEEIFGPVIVVGSF 414
++ ++ GG + G++V PT++ + + E FGP++ V +
Sbjct: 419 KKDPELEILYGG---------QYDKSQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEY 469
Query: 415 KD--YKEALDIA-NDSDYGLGSAIFSKDIVTCHKFAQDVE--AGMVWINS--SNDVDINV 467
D + E DI N S Y L AIF+KD + ++ AG +IN + V
Sbjct: 470 PDTEFNEICDIIDNTSQYALTGAIFAKDRKAIEYADEKLKFSAGNFYINDKCTGAVVSQQ 529
Query: 468 PFGGVKMSGHGRELGEYG-LANFTNVKSVHVN 498
FGG +MSG + G L+ F ++++ N
Sbjct: 530 WFGGARMSGTDDKAGGPNILSRFVSIRNTKEN 561
>SPBC24C6.04 [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrogenase
Length = 548
Score = 122 bits (307), Expect = 1e-27
Identities = 125/464 (26%), Positives = 206/464 (43%), Gaps = 40/464 (8%)
Query: 58 VDLAVKAARDAFPGWKATPAIEKRDLFYKLAGLLERDIDI-LSKIESLDTGKPIANNAKY 116
V+ A++AA W++ P ++ +F K A L+ L + GK I
Sbjct: 83 VEDAIEAALRGKKVWESLPFADRSAIFLKAAHLISTKYRYKLMAATMIGQGKNIWQAEID 142
Query: 117 DILEVVEVLKYYAGWIDKAGGQSFAPSSEKLAYTL-HQPL-GVVGCIIPFNYPLAMMSWK 174
+E+++ L++ + + ++ + + ++PL G V I PFN+ +
Sbjct: 143 AGMEIIDFLRFNTKYASELYASQPPENTPGVWNRMEYRPLEGFVYAITPFNFTAIAGNLA 202
Query: 175 WTAIATGNTTVFKSADQTPLSILYFAKLVKEAGFPAGVFNVLSGTGASVGSAIVKHTGVD 234
+ GN + K +D LS ++ +EAG PAG + G V H
Sbjct: 203 AAPLLMGNVVLMKPSDHAVLSSYIVYQIFREAGLPAGALQFIPGDAVEVSKVCFNHPEFA 262
Query: 235 KIAFTGSTAV--------GQIIQQQSAVNLKPITLECGGKSANMIFEDCDLEQAVKWSAW 286
+ FTGSTAV G+ + I E GGK+ +++ +++ AV +
Sbjct: 263 GLHFTGSTAVFRSLWGTIGENVANGKYRTYPKIVGETGGKNFHLVHSSAEIKSAVVNAVR 322
Query: 287 GIFNNMGQICSGTSRVFVQESIYEE-FVAQLADHVKKTYIVGAP-SDDAVIVGP---QVS 341
F GQ CS SR++V + +E F +L V K+ VGAP +D A VGP Q S
Sbjct: 323 AAFEYQGQKCSALSRLYVSKYAWENGFRDELTKQV-KSLKVGAPLTDFANFVGPVIHQAS 381
Query: 342 KKQQERVLEYIKIGIEEGCKVPLGGLGAPEPIANDPALANGYYVKPTILADVKASYRIAK 401
+ ++VLE + +V GG A+D + G++V+PT+L + I
Sbjct: 382 FNKLKKVLE--SAASDSEIEVLAGGK------ADD---SEGFFVEPTVLLSKNPKHDIFV 430
Query: 402 EEIFGPVIVVGSFKDYKEALDIAND-----SDYGLGSAIFSKDIVTCHKFAQDVE--AGM 454
E+FGPV+ V ++D + LD D + YGL +IF++D V K + AG
Sbjct: 431 NELFGPVLSVYVYED--DNLDAVCDLIDTTTPYGLTGSIFAQDRVVVRKLTDRLRNAAGN 488
Query: 455 VWINS--SNDVDINVPFGGVKMSGHGRELGE-YGLANFTNVKSV 495
+IN + V PFGG + SG + G L+ F + +S+
Sbjct: 489 FYINDKCTGAVVGEQPFGGARASGTNDKAGSGMILSRFVSPRSI 532
>At1g44170 [C] KOG2456 Aldehyde dehydrogenase
Length = 484
Score = 120 bits (302), Expect = 4e-27
Identities = 107/404 (26%), Positives = 184/404 (45%), Gaps = 34/404 (8%)
Query: 105 DTGKPIANNAKYDIL----EVVEVLKYYAGWIDKAGGQSFAPSSEKLAYTLHQPLGVVGC 160
D GKP ++ Y++ + LK W+ ++ + A + +PLGVV
Sbjct: 59 DLGKPELESSVYEVSLLRNSIKLALKQLKNWMAPEKAKTSLTTFPASAEIVSEPLGVVLV 118
Query: 161 IIPFNYP-LAMMSWKWTAIATGNTTVFKSADQTPLSILYFAKLVKEAGFPAGVFNVLSGT 219
I +NYP L + AI+ GN V K ++ P S KL+++ P+ V V
Sbjct: 119 ISAWNYPFLLSIDPVIGAISAGNAVVLKPSELAPASSALLTKLLEQYLDPSAVRVV---E 175
Query: 220 GASVGSAIVKHTGVDKIAFTGSTAVGQIIQQQSAVNLKPITLECGGKSANMIFEDCDLEQ 279
GA ++ + DKI +TGS+ +G++I +A +L P+ LE GGKS ++ D DL+
Sbjct: 176 GAVTETSALLEQKWDKIFYTGSSKIGRVIMAAAAKHLTPVVLELGGKSPVVVDSDTDLKV 235
Query: 280 AVK---WSAWGIFNNMGQICSGTSRVFVQESIYEEFVAQLADHVKKTYIVGAPSDDAVIV 336
V+ WG N GQ C + + + + + ++K Y G ++ +
Sbjct: 236 TVRRIIVGKWGC--NNGQACVSPDYILTTKEYAPKLIDAMKLELEKFY--GKNPIESKDM 291
Query: 337 GPQVSKKQQERVLEYIKIGIEEGCKVPLGGLGAPEPIANDPALANGYYVKPTILADVKAS 396
V+ +R+ + + E K+ GG E + + PTIL DV
Sbjct: 292 SRIVNSNHFDRLSKLLD-EKEVSDKIVYGGEKDRENLK----------IAPTILLDVPLD 340
Query: 397 YRIAKEEIFGPVIVVGSFKDYKEALDIANDSDYGLGSAIFSKDIVTCHKFAQDVEAGMVW 456
I EEIFGP++ + + + +E+ D+ L + +F+ + +FA V AG +
Sbjct: 341 SLIMSEEIFGPLLPILTLNNLEESFDVIRSRPKPLAAYLFTHNKKLKERFAATVSAGGIV 400
Query: 457 INSSNDVDIN-----VPFGGVKMSGHGRELGEYGLANFTNVKSV 495
+ ND+ ++ +PFGGV SG G G++ F++ K+V
Sbjct: 401 V---NDIAVHLALHTLPFGGVGESGMGAYHGKFSFDAFSHKKAV 441
>Hs4502043 [C] KOG2456 Aldehyde dehydrogenase
Length = 468
Score = 119 bits (299), Expect = 8e-27
Identities = 108/438 (24%), Positives = 192/438 (43%), Gaps = 29/438 (6%)
Query: 62 VKAARDAFPGWKATPAIEKRDLFYKLAGLLERDIDILSKIESLDTGKPIANNAKYDIL-- 119
++ R+AF + PA + L L+ + +L + D K + ++
Sbjct: 8 LRRLREAFHAGRTRPAEFRAAQLQGLGRFLQENKQLLHDALAQDLHKSAFESEVSEVAIS 67
Query: 120 --EVVEVLKYYAGWI-DKAGGQSFAPSSEKLAYTLHQPLGVVGCIIPFNYPLAMMSWKWT 176
EV L+ W+ D+ ++ A + A+ +P G+V I P+NYPL +
Sbjct: 68 QGEVTLALRNLRAWMKDERVPKNLATQLDS-AFIRKEPFGLVLIIAPWNYPLNLTLVPLV 126
Query: 177 -AIATGNTTVFKSADQTPLSILYFAKLVKEAGFPAGVFNVLSGTGASVGSAIVKHTGVDK 235
A+A GN V K ++ + A+++ + F V+ G G +++H D
Sbjct: 127 GALAAGNCVVLKPSEISKNVEKILAEVLPQY-VDQSCFAVVLGGPQETGQ-LLEHR-FDY 183
Query: 236 IAFTGSTAVGQIIQQQSAVNLKPITLECGGKSANMIFEDCDLEQAVKWSAWGIFNNMGQI 295
I FTGS VG+I+ +A +L P+TLE GGK+ + ++CD + AW + N GQ
Sbjct: 184 IFFTGSPRVGKIVMTAAAKHLTPVTLELGGKNPCYVDDNCDPQTVANRVAWFRYFNAGQT 243
Query: 296 CSGTSRVFVQESIYEEFVAQLADHVKKTYIVGAPSDDAVIVGPQVSKKQQERVLEYIKIG 355
C V + E + L + + Y G + +G +++KQ +R+ + G
Sbjct: 244 CVAPDYVLCSPEMQERLLPALQSTITRFY--GDDPQSSPNLGRIINQKQFQRLRALLGCG 301
Query: 356 IEEGCKVPLGGLGAPEPIANDPALANGYYVKPTILADVKASYRIAKEEIFGPVIVVGSFK 415
+V +GG + + Y+ PT+L DV+ + +EEIFGP++ + + +
Sbjct: 302 -----RVAIGG----------QSDESDRYIAPTVLVDVQEMEPVMQEEIFGPILPIVNVQ 346
Query: 416 DYKEALDIANDSDYGLGSAIFSKDIVTCHKFAQDVEAGMVWINSS--NDVDINVPFGGVK 473
EA++ N + L FS + +G N + ++PFGGV
Sbjct: 347 SLDEAIEFINRREKPLALYAFSNSSQVVKRVLTQTSSGGFCGNDGFMHMTLASLPFGGVG 406
Query: 474 MSGHGRELGEYGLANFTN 491
SG GR G++ F++
Sbjct: 407 ASGMGRYHGKFSFDTFSH 424
>YMR110c [C] KOG2456 Aldehyde dehydrogenase
Length = 532
Score = 118 bits (296), Expect = 2e-26
Identities = 98/351 (27%), Positives = 166/351 (46%), Gaps = 27/351 (7%)
Query: 156 GVVGCIIPFNYPLAM-MSWKWTAIATGNTTVFKSADQTPLSILYFAKLVKEAGFPAGVFN 214
G V I PFN+PL + + A+A GNT V K ++ TP + + L+ AGFP G+
Sbjct: 130 GSVLIIAPFNFPLLLAFAPLAAALAAGNTIVLKPSELTPHTAVVMENLLTTAGFPDGLIQ 189
Query: 215 VLSGTGASVGSAIVKHTGVDKIAFTGSTAVGQIIQQQSAVNLKPITLECGGKSANMI--- 271
V+ G + ++ D I +TGS VG I+ +++A +L P LE GGKS I
Sbjct: 190 VVQGA-IDETTRLLDCGKFDLIFYTGSPRVGSIVAEKAAKSLTPCVLELGGKSPTFITEN 248
Query: 272 FEDCDLEQAVKWSAWGIFNNMGQICSGTSRVFVQESIYEEFVAQLADHVKKTYIVGAPS- 330
F+ +++ A+K +G F N GQIC + V +SIY + + + + + Y PS
Sbjct: 249 FKASNIKIALKRIFFGAFGNSGQICVSPDYLLVHKSIYPKVIKECESVLNEFY----PSF 304
Query: 331 DDAVIVGPQVSKKQQERVLEYIKIGIEEGCKVPLGGLGAPEPIANDPALANGYYVKPTIL 390
D+ + + ++ + I G K+ P I+ + + V PTI+
Sbjct: 305 DEQTDFTRMIHEPAYKKAV--ASINSTNGSKI------VPSKISINSDTEDLCLVPPTIV 356
Query: 391 ADVKASYRIAKEEIFGPVIVVGSFKDYKEALD-IANDSDYGLGSAIFSKDIVTCHKFAQD 449
++ + K+E F PV+ + ++D E ++ I + D L IFS ++
Sbjct: 357 YNIGWDDPLMKQENFAPVLPIIEYEDLDETINKIIEEHDTPLVQYIFSDSQTEINRILTR 416
Query: 450 VEAGMVWINSSNDVDINV-----PFGGVKMSGHGRELGEYGLANFTNVKSV 495
+ +G + D I+V PFGG+ SG+G G YG F++ +++
Sbjct: 417 LRSGDCVV---GDTVIHVGITDAPFGGIGTSGYGNYGGYYGFNTFSHERTI 464
>Hs4502045 [C] KOG2456 Aldehyde dehydrogenase
Length = 385
Score = 114 bits (286), Expect = 3e-25
Identities = 89/342 (26%), Positives = 158/342 (46%), Gaps = 23/342 (6%)
Query: 153 QPLGVVGCIIPFNYPLAM-MSWKWTAIATGNTTVFKSADQTPLSILYFAKLVKEAGFPAG 211
+P G+V I P+NYPL + + + GN V K ++ + + A+++ +
Sbjct: 22 EPFGLVLIIAPWNYPLNLTLVLLVGTLPAGNCVVLKPSEISQGTEKVLAEVLPQY-LDQS 80
Query: 212 VFNVLSGTGASVGSAIVKHTGVDKIAFTGSTAVGQIIQQQSAVNLKPITLECGGKSANMI 271
F V+ G G +++H +D I FTGS VG+I+ + +L P+TLE GGK+ +
Sbjct: 81 CFAVVLGGPQETGQ-LLEHK-LDYIFFTGSPRVGKIVMTAATKHLTPVTLELGGKNPCYV 138
Query: 272 FEDCDLEQAVKWSAWGIFNNMGQICSGTSRVFVQESIYEEFVAQLADHVKKTYIVGAPSD 331
++CD + AW + N GQ C V + E + L + + Y G
Sbjct: 139 DDNCDPQTVANRVAWFCYFNAGQTCVAPDYVLCSPEMQERLLPALQSTITRFY--GDDPQ 196
Query: 332 DAVIVGPQVSKKQQERVLEYIKIGIEEGCKVPLGGLGAPEPIANDPALANGYYVKPTILA 391
+ +G +++KQ +R+ + G +V +GG + + Y+ PT+L
Sbjct: 197 SSPNLGRIINQKQFQRLRALLGCG-----RVAIGG----------QSNESDRYIAPTVLV 241
Query: 392 DVKASYRIAKEEIFGPVIVVGSFKDYKEALDIANDSDYGLGSAIFSKDIVTCHKFAQDVE 451
DV+ + + +EEIFGP++ + + + EA+ N + L FS ++ +
Sbjct: 242 DVQETEPVMQEEIFGPILPIVNVQSVDEAIKFINRQEKPLALYAFSNSRQVVNQMLERTS 301
Query: 452 AGMVWINSSNDVD--INVPFGGVKMSGHGRELGEYGLANFTN 491
+G N ++VPFGGV SG GR G++ F++
Sbjct: 302 SGSFGGNEGFTYISLLSVPFGGVGHSGMGRYHGKFTFDTFSH 343
>Hs20546780 [C] KOG2450 Aldehyde dehydrogenase
Length = 637
Score = 109 bits (273), Expect = 8e-24
Identities = 90/335 (26%), Positives = 164/335 (48%), Gaps = 23/335 (6%)
Query: 155 LGVVGCIIPFNYPLAMMSWK-WTAIATGNTTVFKSADQTPLSILYFAKLVKEAGFPAGVF 213
+GV+G I+P + M W+ A+A G T V +P +L A+L E G G+
Sbjct: 1 MGVIGLILPPTFSFLEMMWRICPALAVGCTVVALVPPASPAPLL-LAQLAGELGPFPGIL 59
Query: 214 NVLSGTGASVGSAIVKHTGVDKIAFTGSTAVGQIIQQQSAVNLKPITLECGGKSANMIFE 273
NVLSG AS+ + G+ K+AF G+ G+ +++ A + L G +S ++ +
Sbjct: 60 NVLSGP-ASLVPILASQPGIRKVAFCGAPEEGRALRRSLAGECAELGLALGTESLLLLTD 118
Query: 274 DCDLEQAVKWSAWGIFNNMGQICSGTSRVFVQESIYEEFVAQLADHVKKTYIVGAPSDDA 333
D++ AV+ +++ G G R+ +QES+++E + +L + + + G D A
Sbjct: 119 TADVDSAVEGVVDAAWSDRGP---GGLRLLIQESVWDEAMRRLQERMGRLRS-GRGLDGA 174
Query: 334 VIVGPQVSKKQQERVLEYIKIGIEEGCKV-PLGGLGAPEPIANDPALANGYYVKPTILAD 392
V +G + + V +++ +G +V G + + P + PT++++
Sbjct: 175 VDMGAR-GAAACDLVQRFVREAQSQGAQVFQAGDVPSERP-----------FYPPTLVSN 222
Query: 393 VKASYRIAKEEIFGPVIVVGSFKDYKEALDIANDSDYGLGSAIFSKDIVTCHKFAQDVEA 452
+ + A+ E+ PV+V F+ KEAL +AN + G ++++S+ + + ++
Sbjct: 223 LPPASPCAQVEVPWPVVVASPFRTAKEALLVANGTPRGGSASVWSERLGQALELGYGLQV 282
Query: 453 GMVWINSSNDVDINVPFGGVKMSG---HGRELGEY 484
G VWIN+ D +VP GG K SG HG G Y
Sbjct: 283 GTVWINAHGLRDPSVPTGGCKESGCSWHGGPDGLY 317
Score = 76.6 bits (187), Expect = 8e-14
Identities = 69/244 (28%), Positives = 105/244 (42%), Gaps = 6/244 (2%)
Query: 17 PLGLFINNEYVEAHGSETLTSYNPSSGEEICKVQCADPKIDVDLAVKAARDAFPGWKATP 76
P GLF+ + +A G+ + SSG V K D+ AV+AA AFPGW
Sbjct: 362 PYGLFVGGRF-QAPGARSSRPIRDSSGNLHGYVAEGGAK-DIRGAVEAAHQAFPGWAGQS 419
Query: 77 AIEKRDLFYKLAGLLERDIDILSKIESLDTGKPIANNAKYDILEVVEVLKYYAGWIDKAG 136
+ L + LA LER L+ + A A+ ++ L+ + + G
Sbjct: 420 PGARAALLWALAAALERRKSTLASRLERQGAELKAAEAEVELS--ARRLRAWGARVQAQG 477
Query: 137 GQSFAPSSEKLAYTLHQPLGVVGCIIPFNYPL-AMMSWKWTAIATGNTTVFKSADQTPLS 195
L +PLGV+ + P +PL A +S A+A GNT V + PL
Sbjct: 478 HTLQVAGLRGPVLRLREPLGVLAVVCPDEWPLLAFVSLLAPALAYGNTVVMVPSAACPLL 537
Query: 196 ILYFAKLVKEAGFPAGVFNVLSGTGASVGSAIVKHTGVDKIAFTGSTAVGQIIQQQSAVN 255
L + + FPAG+ NV++G + + H V + + GS Q ++ SA N
Sbjct: 538 ALEVCQDMATV-FPAGLANVVTGDRDHLTRCLALHQDVQAMWYFGSAQGSQFVEWASAGN 596
Query: 256 LKPI 259
LKP+
Sbjct: 597 LKPV 600
>7304212 [C] KOG2456 Aldehyde dehydrogenase
Length = 561
Score = 105 bits (262), Expect = 2e-22
Identities = 85/310 (27%), Positives = 144/310 (46%), Gaps = 21/310 (6%)
Query: 152 HQPLGVVGCIIPFNYPLAMMSWKW-TAIATGNTTVFKSADQTPLSILYFAKLVKEAGFPA 210
+ P GVV I +NYPL ++ +AIA GN V K ++ + A ++ +
Sbjct: 102 NDPFGVVLVIGAWNYPLQLLLVPVASAIAAGNCVVIKPSEIAANCAKFIADVIPKY-LDN 160
Query: 211 GVFNVLSGTGASVGSAIVKHTGVDKIAFTGSTAVGQIIQQQSAVNLKPITLECGGKSANM 270
+ V+ G + + + D I +TGST VG+II + L P TLE GGKS
Sbjct: 161 DCYPVVCGGPSETAELLNQR--FDYIFYTGSTRVGKIIHAAANKYLTPTTLELGGKSPCY 218
Query: 271 IFEDCDLEQAVKWSAWGIFNNMGQICSGTSRVFVQESIYEEFVAQLADHVKKTYIVGAPS 330
I + D+ AVK WG N GQ C + + + E+F+ + D +K+ Y G
Sbjct: 219 IDKSVDMRTAVKRILWGKLINCGQTCIAPDYILCSKEVQEKFIVEAKDVLKEWY--GENI 276
Query: 331 DDAVIVGPQVSKKQQERVLEYIKIGIEEGCKVPLGGLGAPEPIANDPALANGYYVKPTIL 390
+ + ++ +R+L +K G +V +GG A+ +++PTIL
Sbjct: 277 QSSPDLSRVINANNFQRLLGLMKSG-----RVAVGG----------NYDASERFIEPTIL 321
Query: 391 ADVKASYRIAKEEIFGPVIVVGSFKDYKEALDIANDSDYGLGSAIFSKDIVTCHKFAQDV 450
DVK + I +EEIFGP++ + + + +A+ N + L IF+ + F
Sbjct: 322 VDVKETDPIMEEEIFGPILPIFNVESAYDAIKFINARESPLVLYIFTPTAEVQNLFINGT 381
Query: 451 EAGMVWINSS 460
++G + +N +
Sbjct: 382 QSGGLCVNDT 391
>7300788 [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrogenase
Length = 1590
Score = 105 bits (261), Expect = 2e-22
Identities = 85/348 (24%), Positives = 158/348 (44%), Gaps = 37/348 (10%)
Query: 156 GVVGCIIPFNYPLAMMSWKWTAIATGNTTVFKSADQTPLSILYFAKLVKEAGFPAGVFNV 215
G V I PFN+ + +T GN+ ++K +D LS + K ++EAG P GV N
Sbjct: 235 GFVAAISPFNFTGIAANLAYTPALMGNSVIWKPSDSAILSNYFVFKALREAGVPDGVVNF 294
Query: 216 LSGTGASVGSAIVKHTGVDKIAFTGSTAVGQIIQQQSAVNLK------PITLECGGKSAN 269
+ + S + +H + I FTG++ V +++ Q A N+ + E GGK+ +
Sbjct: 295 VPAEETTFASVVTQHPKLAGINFTGTSTVLKVLWQLVAQNINFYQNYPRLVGEGGGKNFH 354
Query: 270 MIFEDCDLEQAVKWSAWGIFNNMGQICSGTSRVFVQESIYEEFVAQLADHVKKTYIVGAP 329
+ + E AV + F GQ CS S ++V ES+++ + + + + +V
Sbjct: 355 FVHSSAEPETAVACTIRAAFEYAGQKCSSCSMLYVPESLWQNHIREPLLEITASLVV--- 411
Query: 330 SDDAV----IVGPQVSKKQQERVLEYIK-IGIEEGCKVPLGGLGAPEPIANDPALANGYY 384
DA ++++ +R+ +++ I C++ +GG GYY
Sbjct: 412 RQDATYCDSFCSAVINRRAYDRIYMWLRYIDQSPSCQILVGG---------SCDKRRGYY 462
Query: 385 VKPTILADVKASYRIAKEEIFGPVIVVGSFKDY--KEALDIANDSDYGLGSAIFSKDIVT 442
V PT++ I +EE+ P++ V + D+ KE ++ ++GL ++F++D
Sbjct: 463 VDPTVVLVKDLDNIICREELLAPILGVYVYPDHKLKETMEKVAQINHGLTGSVFAQD--- 519
Query: 443 CHKFAQDV-EAGMVWINSSNDVDINV-------PFGGVKMSGHGRELG 482
F ++ +A V + + N D + PFG M+G +LG
Sbjct: 520 -QNFIEEAYDAFRVNVGNLNVNDKSTGLMVGQQPFGAGHMTGTSDKLG 566
>At4g36250 [C] KOG2456 Aldehyde dehydrogenase
Length = 433
Score = 98.2 bits (243), Expect = 3e-20
Identities = 93/362 (25%), Positives = 155/362 (42%), Gaps = 75/362 (20%)
Query: 140 FAPSSEKLAYTLHQPLGVVGCIIPFNYPLAM-MSWKWTAIATGNTTVFKSADQTPLSILY 198
F P+ K+ + +P G V + +N+P+++ + AIA GNT + KS++ +P + +
Sbjct: 97 FYPAKGKV---ISEPYGTVLVLSSWNFPISLSLDPLIGAIAAGNTVLLKSSELSPNASAF 153
Query: 199 FAKLVKEAGFPAGVFNVLSGTGASVGSAIVKHTGVDKIAFTGSTAVGQIIQQQSAVNLKP 258
AK + A V+ G G V + +++H DKI FTGS +G+II +A +L P
Sbjct: 154 LAKTIP-AYLDTKAIKVIEG-GPDVATILLQHQW-DKIFFTGSPKIGRIIMAAAAQHLTP 210
Query: 259 ITLECGGKSANMIFEDCDLEQAVKWSAWGIFNNMGQICSGTSRVFVQESIYEEFVAQLAD 318
+TLE GGKS C V +++S + L
Sbjct: 211 VTLELGGKS----------------------------CISVDYVLIEKSFAPTLIDMLKP 242
Query: 319 HVKKTYIVGAPSDDAVIVGPQVSKKQQERVLEYIKIGIEEGCKVPLGGLGAPEPIANDPA 378
+K + G ++ + +K +R+ + +DP
Sbjct: 243 TIKSFF--GENPKESGCLSRIANKHHVQRL----------------------SRLLSDP- 277
Query: 379 LANGYYVKPTILADVKASYRIAKEEIFGPVIVVGSFKDYKEALDIANDSDYGLGSAIFSK 438
+PTIL D I EEIFGP++ + + +D +E++ I N L F+
Sbjct: 278 -------RPTILLDPPLDSEIMNEEIFGPILPIITVRDIQESIGIINTKPKPLAIYAFTN 330
Query: 439 DIVTCHKFAQDVEAGMVWINSSNDVDIN-----VPFGGVKMSGHGRELGEYGLANFTNVK 493
D + + +G V + NDV I +PFGGV SG GR G+Y F++ K
Sbjct: 331 DENLKTRILSETSSGSV---TFNDVMIQYMCDALPFGGVGESGIGRYHGKYSFDCFSHEK 387
Query: 494 SV 495
++
Sbjct: 388 AI 389
>7294423 [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrogenase
Length = 560
Score = 80.9 bits (198), Expect = 4e-15
Identities = 102/450 (22%), Positives = 194/450 (42%), Gaps = 47/450 (10%)
Query: 58 VDLAVKAARDAFPGWKATPAIEKRDLFYKLAGLLERDIDILSKIESLDTGKPIANNAKYD 117
++ A+K+A A W P ++ ++ + A ++E D ++ ++ + T A++A D
Sbjct: 102 IEAAIKSALSAQGTWSLVPIAQRLAIWRRAATIIEED-ELRLRVFLMMTLSKTADDATRD 160
Query: 118 ILEVVEVLKYYAGWIDKAGGQSFAPSSEKLAY-TLH-QPL-GVVGCIIPFNYPLAMMSWK 174
I ++ L+ A +++ F + + + H +P+ G V + PF S
Sbjct: 161 IRRLLTSLRANADYLEHLSELRFEIQGDMNVFPSFHLRPMDGFVAALAPFESVALSSSLA 220
Query: 175 WTAIATGNTTVFK-SADQTPLSILYFAKLVKEAGFPAGVFNVLSGTGASVGSAIVKHTGV 233
GNT ++ S + P+S L F + +EAG P+GV N + + T
Sbjct: 221 LCPALMGNTVLWNPSLEVAPVSYLIF-RAFQEAGLPSGVINFV-----PANERLFLDTIT 274
Query: 234 DKIAFTGSTA---------VGQII--QQQSAVNLKPITLECGGKSANMIFEDCDLEQAVK 282
D + F G V +++ + + + + EC G++ + + +E V
Sbjct: 275 DAVHFAGLNTQASAAFYRHVHKLVSDRMERYICFPRLVAECPGQNFHFVHASAKVESVVS 334
Query: 283 WSAWGIFNNMGQICSGTSRVFVQESIYEEFVAQLADHVKKTYIVGAPSDDAVIVGPQV-- 340
+ F GQ + SR++V S++ +L + ++ +G P + +G V
Sbjct: 335 ATVQAAFGFAGQYANSLSRMYVPSSMWPRLREELVEATEQ-LTIGDPIESETDIGAMVHI 393
Query: 341 -SKKQQERVLEYIKIGIEEGCKVPLGGLGAPEPIANDPALANGYYVKPTILADVKASYRI 399
++ +++L+ K +E+ C GG +D + G +V PTI+ +
Sbjct: 394 NDFRRMQKLLQRTK-NMEQLC----GG------SCDD---STGRFVDPTIVRVSDPLDPL 439
Query: 400 AKEEIFGPVIVVGSFKD--YKEALDI-ANDSDYGLGSAIF-SKDIVTCHKFAQ-DVEAGM 454
E GP + V + D + EAL + AN S Y L +IF S+D V H Q + A
Sbjct: 440 LCEPCCGPFLPVFVYSDDSFSEALKLAANQSRYALSGSIFASQDEVILHCLNQLRMSASN 499
Query: 455 VWINS--SNDVDINVPFGGVKMSGHGRELG 482
+++N + PFGG ++SG + G
Sbjct: 500 LYVNERCTGSTYGLTPFGGNRLSGTNDKSG 529
>Hs20481620 [C] KOG2456 Aldehyde dehydrogenase
Length = 292
Score = 78.6 bits (192), Expect = 2e-14
Identities = 65/231 (28%), Positives = 105/231 (45%), Gaps = 12/231 (5%)
Query: 148 AYTLHQPLGVVGCIIPFNYPLAMMSWKWT-AIATGNTTVFKSADQTPLSILYFAKLVKEA 206
A+ +P G+V I P+NYPL + A+A GN V K ++ + A+++ +
Sbjct: 61 AFIRKEPFGLVLIIAPWNYPLNLTLVPLVGALAAGNCVVLKPSEISKNVEKILAEVLPQY 120
Query: 207 GFPAGVFNVLSGTGASVGSAIVKHTGVDKIAFTGSTAVGQIIQQQSAVNLKPITLECGGK 266
F V+ G G +++H D I FTGS VG+I+ +A +L P+TLE GGK
Sbjct: 121 -VDQSCFAVVLGGPQETGQ-LLEHR-FDYIFFTGSPRVGKIVMTAAAKHLTPVTLELGGK 177
Query: 267 SANMIFEDCDLEQAVKWSAWGIFNNMGQICSGTSRVFVQESIYEEFVAQLADHVKKTYIV 326
+ + ++CD + AW + N GQ C V + E + L + + Y
Sbjct: 178 NPCYVDDNCDPQTVANRVAWFRYFNAGQTCVAPDYVLCSPEMQERLLPALQSTITRFY-- 235
Query: 327 GAPSDDAVIVGPQVSKKQQERVLEYIKIGIEEGCKVPLGGLGAPEPIANDP 377
G + +G +++KQ +R+ + GC V G A IA P
Sbjct: 236 GDDPQSSPNLGRIINQKQFQRLRALL------GCGVWPLGARAMRAIATSP 280
>At4g34240 [C] KOG2456 Aldehyde dehydrogenase
Length = 533
Score = 64.3 bits (155), Expect = 4e-10
Identities = 79/326 (24%), Positives = 136/326 (41%), Gaps = 41/326 (12%)
Query: 177 AIATGNTTVFKSADQTPLSILYFAKLVKEAGFPAGVFNVLSGTGASVGSAIVKHTGVDKI 236
AIA GN V K ++ P + AKL E V+ G G +A++ DKI
Sbjct: 196 AIAAGNAVVLKPSEIAPAASSLLAKLFSEY-LDNTTIRVIEG-GVPETTALLDQKW-DKI 252
Query: 237 AFTGSTAV--GQIIQQQSAVNLKPITLECGGKSANMIFEDCDLEQAVKWSAWGIFNNMGQ 294
FT + + +I++ +S + + L+ + A KW+ N GQ
Sbjct: 253 FFTDLSLLLKHKIVKFRSHTLIVVLWLKVAARRII----------AGKWAC-----NSGQ 297
Query: 295 ICSGTSRVFVQESIYEEFVAQLADHVKKTYIVGA-PSDDAVIVGPQVSKKQQERVLEYIK 353
C G V + + + L ++ + A S D + K+ E +L+
Sbjct: 298 ACIGVDYVITTKDFASKLIDALKTELETFFGQNALESKDLSRIVNSFHFKRLESMLK--- 354
Query: 354 IGIEEGC--KVPLGGLGAPEPIANDPALANGYYVKPTILADVKASYRIAKEEIFGPVIVV 411
E G K+ GG + + + PTIL DV + + +EEIFGP++ +
Sbjct: 355 ---ENGVANKIVHGGRITEDKLK----------ISPTILLDVPEASSMMQEEIFGPLLPI 401
Query: 412 GSFKDYKEALDIANDSDYGLGSAIFSKDIVTCHKFAQDVEAGMVWINSS--NDVDINVPF 469
+ + ++ + L + +F+ + +F QDV AG + IN + + ++PF
Sbjct: 402 ITVQKIEDGFQVIRSKPKPLAAYLFTNNKELEKQFVQDVSAGGITINDTVLHVTVKDLPF 461
Query: 470 GGVKMSGHGRELGEYGLANFTNVKSV 495
GGV SG G G++ F++ K V
Sbjct: 462 GGVGESGIGAYHGKFSYETFSHKKGV 487
>Hs20479244 [C] KOG2450 Aldehyde dehydrogenase
Length = 292
Score = 56.6 bits (135), Expect = 8e-08
Identities = 33/104 (31%), Positives = 57/104 (54%), Gaps = 3/104 (2%)
Query: 384 YVKPTILADVKASYRIAKEEIFGPVIVVGSFKDYKEALDIANDSDYGLGSAIFSKDIVTC 443
+ PT+++++ + A+ E+ PV+V F+ KEAL +AN + G ++++S+ +
Sbjct: 60 FYPPTLVSNLPPASPCAQVEVPWPVVVASPFRTAKEALLVANGTPRGGSASVWSERLGQA 119
Query: 444 HKFAQDVEAGMVWINSSNDVDINVPFGGVKMSG---HGRELGEY 484
+ ++ G VWIN+ D +VP GG K SG HG G Y
Sbjct: 120 LELGYGLQVGTVWINAHGLRDPSVPTGGCKESGCSWHGGPDGLY 163
>At5g62530 [C] KOG2451 Aldehyde dehydrogenase
Length = 563
Score = 53.1 bits (126), Expect = 9e-07
Identities = 75/297 (25%), Positives = 127/297 (42%), Gaps = 39/297 (13%)
Query: 138 QSFAPSSEKLAYTLHQ---PLGVVGCIIPFNYPLAM-MSWKWTAIATGNTTVFKSADQTP 193
+SFA L H P G V + PFN+PL + + A+ GN + K +
Sbjct: 184 RSFAIPGNHLGQQSHGYRWPYGPVTIVTPFNFPLEIPLLQLMGALYMGNKPLLKVDSKVS 243
Query: 194 LSILYFAKLVKEAGFPAGVFNVLSGTGASVGSAIVKHTGVDKIAFTGSTAVGQIIQQQSA 253
+ + +L+ G PA + ++ G ++ +++ FTGS+ V + + A
Sbjct: 244 IVMEQMMRLLHYCGLPAEDVDFINSDGKTMNKILLE-ANPRMTLFTGSSRVAEKL----A 298
Query: 254 VNLKP-ITLECGGKSANMIFEDCDLEQAVKWSA-WGIFNNMGQICSGTSRVFVQESIYEE 311
++LK I LE G ++ D V W + GQ CS S +FV E+ +
Sbjct: 299 LDLKGRIRLEDAGFDWKVLGPDVQEVDYVAWQCDQDAYACSGQKCSAQSMLFVHENWSKT 358
Query: 312 -FVAQLADHVKKTYIVGAPSDDAVIVGPQVSKKQQERVLEYIKIGIE-EGCKVPLGG--- 366
V++L + ++ + + + +GP V E +LE+++ ++ G K+ GG
Sbjct: 359 PLVSKLKELAERRKL------EDLTIGP-VLTFTTEAMLEHMENLLQIPGSKLLFGGKEL 411
Query: 367 --------LGAPEPIANDPALANGYYVKPTILADVKASYRIAKEEIFGPVIVVGSFK 415
GA EP A Y IL D K +Y + +EIFGP +V +K
Sbjct: 412 KNHSIPSIYGALEPTAV-------YVPIEEILKDNK-TYELVTKEIFGPFQIVTEYK 460
>Hs21614515 [F] KOG2452 Formyltetrahydrofolate dehydrogenase
Length = 505
Score = 51.6 bits (122), Expect = 3e-06
Identities = 30/74 (40%), Positives = 42/74 (56%), Gaps = 3/74 (4%)
Query: 15 QQPLGLFINNEYVEAHGSETLTSYNPSSGEEICKVQCADPKIDVDLAVKAARDAFPG--W 72
+ P LFI E+V+A G++T + NP+ G IC+V A DVD AV AA+DAF W
Sbjct: 419 RMPHQLFIGGEFVDAEGAKTSETINPTDGSVICQVSLAQ-VTDVDKAVAAAKDAFENGRW 477
Query: 73 KATPAIEKRDLFYK 86
A ++ L Y+
Sbjct: 478 GKISARDRGRLMYR 491
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.317 0.136 0.399
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 31,269,541
Number of Sequences: 60738
Number of extensions: 1391179
Number of successful extensions: 3199
Number of sequences better than 1.0e-05: 77
Number of HSP's better than 0.0 without gapping: 65
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 2784
Number of HSP's gapped (non-prelim): 83
length of query: 503
length of database: 30,389,216
effective HSP length: 111
effective length of query: 392
effective length of database: 23,647,298
effective search space: 9269740816
effective search space used: 9269740816
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)