ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIV2505 good R KOG1577 General function prediction only Aldo/keto reductase family proteins
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIV2505 854495 855421 309
(309 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YOR120w [R] KOG1577 Aldo/keto reductase family proteins 362 e-100
YDR368w [R] KOG1577 Aldo/keto reductase family proteins 347 2e-95
SPBC8E4.04 [R] KOG1577 Aldo/keto reductase family proteins 212 5e-55
At2g37770 [R] KOG1577 Aldo/keto reductase family proteins 207 2e-53
At3g53880 [R] KOG1577 Aldo/keto reductase family proteins 204 2e-52
At2g37760 [R] KOG1577 Aldo/keto reductase family proteins 203 2e-52
At2g37790 [R] KOG1577 Aldo/keto reductase family proteins 199 3e-51
SPAC26F1.07 [R] KOG1577 Aldo/keto reductase family proteins 199 6e-51
Hs5174391 [R] KOG1577 Aldo/keto reductase family proteins 194 1e-49
Hs4502049 [R] KOG1577 Aldo/keto reductase family proteins 193 2e-49
At5g62420 [R] KOG1577 Aldo/keto reductase family proteins 187 2e-47
YBR149w [R] KOG1577 Aldo/keto reductase family proteins 186 4e-47
ECU01g0970 [R] KOG1577 Aldo/keto reductase family proteins 186 4e-47
Hs20127592 [R] KOG1577 Aldo/keto reductase family proteins 183 2e-46
CE24243 [R] KOG1577 Aldo/keto reductase family proteins 183 2e-46
7294702 [R] KOG1577 Aldo/keto reductase family proteins 183 3e-46
CE21733 [R] KOG1577 Aldo/keto reductase family proteins 182 4e-46
At2g21250 [R] KOG1577 Aldo/keto reductase family proteins 179 5e-45
7292407 [R] KOG1577 Aldo/keto reductase family proteins 179 5e-45
At2g21260 [R] KOG1577 Aldo/keto reductase family proteins 178 1e-44
At5g01670 [R] KOG1577 Aldo/keto reductase family proteins 177 2e-44
Hs11386205 [R] KOG1577 Aldo/keto reductase family proteins 177 2e-44
Hs4503285 [R] KOG1577 Aldo/keto reductase family proteins 176 5e-44
Hs5453543 [R] KOG1577 Aldo/keto reductase family proteins 174 1e-43
Hs13899261 [R] KOG1577 Aldo/keto reductase family proteins 174 1e-43
7294701 [R] KOG1577 Aldo/keto reductase family proteins 172 6e-43
Hs20127601 [R] KOG1577 Aldo/keto reductase family proteins 172 7e-43
SPAC2F3.05c [R] KOG1577 Aldo/keto reductase family proteins 171 9e-43
7298972 [R] KOG1577 Aldo/keto reductase family proteins 171 1e-42
7292408 [R] KOG1577 Aldo/keto reductase family proteins 169 4e-42
CE10936 [R] KOG1577 Aldo/keto reductase family proteins 163 3e-40
7302301 [R] KOG1577 Aldo/keto reductase family proteins 162 6e-40
YJR096w [R] KOG1577 Aldo/keto reductase family proteins 159 6e-39
SPAP32A8.02 [R] KOG1577 Aldo/keto reductase family proteins 158 1e-38
CE01200 [R] KOG1577 Aldo/keto reductase family proteins 157 2e-38
CE17230 [R] KOG1577 Aldo/keto reductase family proteins 155 5e-38
Hs17450865 [R] KOG1577 Aldo/keto reductase family proteins 153 3e-37
Hs5174695 [R] KOG1577 Aldo/keto reductase family proteins 152 5e-37
CE06776 [R] KOG1577 Aldo/keto reductase family proteins 152 5e-37
7294572 [R] KOG1577 Aldo/keto reductase family proteins 151 1e-36
Hs17465400 [R] KOG1577 Aldo/keto reductase family proteins 149 5e-36
CE10934 [R] KOG1577 Aldo/keto reductase family proteins 149 7e-36
CE24244 [R] KOG1577 Aldo/keto reductase family proteins 145 7e-35
7294573 [R] KOG1577 Aldo/keto reductase family proteins 145 7e-35
CE06751 [R] KOG1577 Aldo/keto reductase family proteins 145 9e-35
At1g59960 [R] KOG1577 Aldo/keto reductase family proteins 142 5e-34
SPAC19G12.09 [R] KOG1577 Aldo/keto reductase family proteins 141 1e-33
Hs22054710 [R] KOG1577 Aldo/keto reductase family proteins 140 2e-33
At1g59950 [R] KOG1577 Aldo/keto reductase family proteins 135 7e-32
YHR104w [R] KOG1577 Aldo/keto reductase family proteins 132 8e-31
CE27788 [R] KOG1577 Aldo/keto reductase family proteins 130 2e-30
Hs20545142 [R] KOG1577 Aldo/keto reductase family proteins 127 2e-29
YDL124w [R] KOG1577 Aldo/keto reductase family proteins 123 4e-28
Hs20470761 [R] KOG1577 Aldo/keto reductase family proteins 122 7e-28
CE15543 [R] KOG1577 Aldo/keto reductase family proteins 118 9e-27
CE06112 [R] KOG1577 Aldo/keto reductase family proteins 118 9e-27
SPBC28F2.05c [R] KOG1577 Aldo/keto reductase family proteins 98 2e-20
Hs20537171 [R] KOG1577 Aldo/keto reductase family proteins 93 4e-19
Hs16156291 [R] KOG1577 Aldo/keto reductase family proteins 87 3e-17
At4g33670 [C] KOG1576 Predicted oxidoreductase 69 9e-12
CE06775 [R] KOG1577 Aldo/keto reductase family proteins 60 3e-09
Hs22058392 [R] KOG1577 Aldo/keto reductase family proteins 58 2e-08
Hs22060498 [R] KOG1577 Aldo/keto reductase family proteins 57 3e-08
At5g53580 [C] KOG1575 Voltage-gated shaker-like K+ channel subun... 57 3e-08
SPAC1F7.12 [C] KOG1575 Voltage-gated shaker-like K+ channel subu... 57 4e-08
At1g04420 [C] KOG1575 Voltage-gated shaker-like K+ channel subun... 54 4e-07
SPCC965.06 [C] KOG1575 Voltage-gated shaker-like K+ channel subu... 49 7e-06
>YOR120w [R] KOG1577 Aldo/keto reductase family proteins
Length = 312
Score = 362 bits (928), Expect = e-100
Identities = 182/301 (60%), Positives = 222/301 (73%), Gaps = 2/301 (0%)
Query: 11 LKLNTGASIPQLGFGTWPSSHADAYTAVITALKTGYRHIDAAAMYGNEAAVGKGIRDSGI 70
L LNTGA IPQ+G GTW S DAY AV+TALK GYRHID AA+Y NE VG+ I+DSG+
Sbjct: 12 LSLNTGAQIPQIGLGTWQSKENDAYKAVLTALKDGYRHIDTAAIYRNEDQVGQAIKDSGV 71
Query: 71 PREEIFVTTKLWNTQQRDPASALDESLERLGLDYVDLFLIHWPVPLKPVG-GPENLLKYP 129
PREEIFVTTKLW TQ +P ALD+SL+RLGLDYVDL+L+HWP L P E++L P
Sbjct: 72 PREEIFVTTKLWCTQHHEPEVALDQSLKRLGLDYVDLYLMHWPARLDPAYIKNEDILSVP 131
Query: 130 TPGIKPQ-IDTEDWSFIKTWELMQTLPKTGKTRAVGVSNFSIKNLEDLLNSSPDVLVPAV 188
T + +D +W+FIKTWELMQ LPKTGKT+AVGVSNFSI NL+DLL S + L PA
Sbjct: 132 TKKDGSRAVDITNWNFIKTWELMQELPKTGKTKAVGVSNFSINNLKDLLASQGNKLTPAA 191
Query: 189 NQFEIHPQLPQTELINYCKSKGIVVEAYCPLGSSSSAMLSDPTIAEIADKYHVKPANVLI 248
NQ EIHP LPQ ELIN+CKSKGIVVEAY PLGS+ + +L +P I EIA K +V+P +V+I
Sbjct: 192 NQVEIHPLLPQDELINFCKSKGIVVEAYSPLGSTDAPLLKEPVILEIAKKNNVQPGHVVI 251
Query: 249 NWGISRGYCVLPKSFTPARIASNKTPVHLSREDTERITKLSETLGVKRYVHPDFEPYPLF 308
+W + RGY VLPKS P RI +N+ LS ED E I +S+ G KR VHP++ P+ +F
Sbjct: 252 SWHVQRGYVVLPKSVNPDRIKTNRKIFTLSTEDFEAINNISKEKGEKRVVHPNWSPFEVF 311
Query: 309 E 309
+
Sbjct: 312 K 312
>YDR368w [R] KOG1577 Aldo/keto reductase family proteins
Length = 312
Score = 347 bits (889), Expect = 2e-95
Identities = 176/302 (58%), Positives = 223/302 (73%), Gaps = 2/302 (0%)
Query: 10 SLKLNTGASIPQLGFGTWPSSHADAYTAVITALKTGYRHIDAAAMYGNEAAVGKGIRDSG 69
+LKLNTGASIP LGFGTW S + Y +VI ALK GYRHIDAAA+Y NE VG+ I+DSG
Sbjct: 11 TLKLNTGASIPVLGFGTWRSVDNNGYHSVIAALKAGYRHIDAAAIYLNEEEVGRAIKDSG 70
Query: 70 IPREEIFVTTKLWNTQQRDPASALDESLERLGLDYVDLFLIHWPVPLKPVGGPE-NLLKY 128
+PREEIF+TTKLW T+QRDP +AL++SL+RLGLDYVDL+L+HWPVPLK + N+L
Sbjct: 71 VPREEIFITTKLWGTEQRDPEAALNKSLKRLGLDYVDLYLMHWPVPLKTDRVTDGNVLCI 130
Query: 129 PT-PGIKPQIDTEDWSFIKTWELMQTLPKTGKTRAVGVSNFSIKNLEDLLNSSPDVLVPA 187
PT IDT++W+FIKTWELMQ LPKTGKT+AVGVSNFSI N+++LL S + +VPA
Sbjct: 131 PTLEDGTVDIDTKEWNFIKTWELMQELPKTGKTKAVGVSNFSINNIKELLESPNNKVVPA 190
Query: 188 VNQFEIHPQLPQTELINYCKSKGIVVEAYCPLGSSSSAMLSDPTIAEIADKYHVKPANVL 247
NQ EIHP LPQ ELI +CK KGIVVEAY P GS+++ +L + I ++A K+ V+PA ++
Sbjct: 191 TNQIEIHPLLPQDELIAFCKEKGIVVEAYSPFGSANAPLLKEQAIIDMAKKHGVEPAQLI 250
Query: 248 INWGISRGYCVLPKSFTPARIASNKTPVHLSREDTERITKLSETLGVKRYVHPDFEPYPL 307
I+W I RGY VL KS P RI SN L +D + I+ LS+ G KR V + +P+
Sbjct: 251 ISWSIQRGYVVLAKSVNPERIVSNFKIFTLPEDDFKTISNLSKVHGTKRVVDMKWGSFPI 310
Query: 308 FE 309
F+
Sbjct: 311 FQ 312
>SPBC8E4.04 [R] KOG1577 Aldo/keto reductase family proteins
Length = 325
Score = 212 bits (540), Expect = 5e-55
Identities = 123/307 (40%), Positives = 178/307 (57%), Gaps = 22/307 (7%)
Query: 13 LNTGASIPQLGFGTWPSSHADAYTAVITALKTGYRHIDAAAMYGNEAAVGKGIRDSGIPR 72
L G IP +G GTW S + AV ALK GYRHID A +YGNE +G+GIR+SG+PR
Sbjct: 17 LPNGDKIPSIGLGTWRSGKDETKNAVCAALKAGYRHIDTAHIYGNEKEIGEGIRESGVPR 76
Query: 73 EEIFVTTKLWNTQQRD--PASALDESLERLGLDYVDLFLIHWPVPLKPVGGPENLLKYPT 130
+I+VT+KLW R AL+++L+ L L+Y+D +LIHWP L + GPE L +
Sbjct: 77 TDIWVTSKLWCNAHRAGLVPLALEKTLQDLNLEYIDAYLIHWPFAL--LSGPEELPR--- 131
Query: 131 PGIKPQIDTEDWSFIKTWELMQTLPKTGKTRAVGVSNFSIKNLEDLLNSSPDVLVPAVNQ 190
K ++ ED +TW+ M+ L +TGK R +G+SNF+ + L+ +L + + P ++Q
Sbjct: 132 -NEKGELIYEDVPIEETWQAMEELLETGKVRYIGISNFNNEYLDRVLKIAK--VKPTIHQ 188
Query: 191 FEIHPQLPQTELINYCKSKGIVVEAYCPLGSSSSAMLSD-------PTIAEIADK--YHV 241
E+HP LPQTE + K I V AY PL + + A SD T+ +IA+ +
Sbjct: 189 MELHPYLPQTEYLEKHKKLQIHVSAYSPLANQNDAYNSDISKLIEHKTLVDIANARGEGI 248
Query: 242 KPANVLINWGISRGYCVLPKSFTPARIASNKTPVHLSREDTERITKLSETLGVKRYVHPD 301
PAN+ I+W + RG VLPKS +RI SN + L+ ++ E I + V+R+ H
Sbjct: 249 TPANIAISWAVKRGTSVLPKSVNESRIVSNFLYIPLTDKEMEAINNIGV---VRRFSHGK 305
Query: 302 FEPYPLF 308
F P P+F
Sbjct: 306 FAPKPMF 312
>At2g37770 [R] KOG1577 Aldo/keto reductase family proteins
Length = 290
Score = 207 bits (526), Expect = 2e-53
Identities = 122/274 (44%), Positives = 157/274 (56%), Gaps = 30/274 (10%)
Query: 12 KLNTGASIPQLGFGTWPSSHADAYTAVITALKTGYRHIDAAAMYGNEAAVG----KGIRD 67
KLNTGA P +G GTW +S AV A+K GYRHID A +YGNE +G K D
Sbjct: 9 KLNTGAKFPSVGLGTWQASPGLVGDAVAAAVKIGYRHIDCAQIYGNEKEIGAVLKKLFED 68
Query: 68 SGIPREEIFVTTKLWNTQQ--RDPASALDESLERLGLDYVDLFLIHWPVPLK--PVG-GP 122
+ RE++F+T+KLW T +D AL+ +L+ L L+YVDL+LIHWP +K VG P
Sbjct: 69 RVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARIKKGSVGIKP 128
Query: 123 ENLLKYPTPGIKPQIDTEDWSFIKTWELMQTLPKTGKTRAVGVSNFSIKNLEDLLNSSPD 182
ENLL P TW+ M+ L +GK RA+GVSNFS K L DLL +
Sbjct: 129 ENLLPVDIP--------------STWKAMEALYDSGKARAIGVSNFSTKKLADLLELAR- 173
Query: 183 VLVPAVNQFEIHPQLPQTELINYCKSKGIVVEAYCPLGSS-----SSAMLSDPTIAEIAD 237
+ PAVNQ E HP QT+L +CKSKG+ + AY PLGS S +L +P + +A+
Sbjct: 174 -VPPAVNQVECHPSWRQTKLQEFCKSKGVHLSAYSPLGSPGTTWLKSDVLKNPILNMVAE 232
Query: 238 KYHVKPANVLINWGISRGYCVLPKSFTPARIASN 271
K PA V + WG+ G+ VLPKS RI N
Sbjct: 233 KLGKSPAQVALRWGLQMGHSVLPKSTNEGRIKEN 266
>At3g53880 [R] KOG1577 Aldo/keto reductase family proteins
Length = 315
Score = 204 bits (518), Expect = 2e-52
Identities = 122/321 (38%), Positives = 173/321 (53%), Gaps = 34/321 (10%)
Query: 7 EFPSLKLNTGASIPQLGFGTWPSSHADAYTAVITALKTGYRHIDAAAMYGNEAAVGKGIR 66
E +LNTGA IP +G GTW ++ AV A+K GY+HID A+ YGNE +GK ++
Sbjct: 4 EIGFFQLNTGAKIPSVGLGTWQAAPGVVGDAVAAAVKIGYQHIDCASRYGNEIEIGKVLK 63
Query: 67 ----DSGIPREEIFVTTKLWNTQQRDP--ASALDESLERLGLDYVDLFLIHWPVPLKPVG 120
D + RE++F+T+K+W T P AL+ +L+ L LDYVDL+L+HWPV LK
Sbjct: 64 KLFDDGVVKREKLFITSKIWLTDLDPPDVQDALNRTLQDLQLDYVDLYLMHWPVRLKKGT 123
Query: 121 ---GPENLLKYPTPGIKPQIDTEDWSFIKTWELMQTLPKTGKTRAVGVSNFSIKNLEDLL 177
PEN++ P TW+ M+ L +GK RA+GVSNFS K L DL+
Sbjct: 124 VDFKPENIMPIDIP--------------STWKAMEALVDSGKARAIGVSNFSTKKLSDLV 169
Query: 178 NSSPDVLVPAVNQFEIHPQLPQTELINYCKSKGIVVEAYCPLGSSSSA-----MLSDPTI 232
++ + PAVNQ E HP Q +L +CKSKGI + Y PLGS + +L P I
Sbjct: 170 EAAR--VPPAVNQVECHPSWQQHKLHEFCKSKGIHLSGYSPLGSPGTTWVKADVLKSPVI 227
Query: 233 AEIADKYHVKPANVLINWGISRGYCVLPKSFTPARIASNKTPV--HLSREDTERITKLSE 290
IA + PA + WG+ G+ +LPKS RI N + + +E ++ +K+ +
Sbjct: 228 EMIAKEIGKSPAQTALRWGLQMGHSILPKSTNEGRIRENFDVLGWSIPKEMFDKFSKIEQ 287
Query: 291 TLGVK--RYVHPDFEPYPLFE 309
V+ +VH PY E
Sbjct: 288 ARLVQGTSFVHETLSPYKTLE 308
>At2g37760 [R] KOG1577 Aldo/keto reductase family proteins
Length = 294
Score = 203 bits (517), Expect = 2e-52
Identities = 119/271 (43%), Positives = 160/271 (58%), Gaps = 28/271 (10%)
Query: 12 KLNTGASIPQLGFGTWPSSHADAYTAVITALKTGYRHIDAAAMYGNEAAVG----KGIRD 67
+LNTGA +P +G GT+ A TA+ A+K GYRHID A++YGNE +G K I D
Sbjct: 9 ELNTGAKLPCVGLGTY----AMVATAIEQAIKIGYRHIDCASIYGNEKEIGGVLKKLIGD 64
Query: 68 SGIPREEIFVTTKLWNTQQ--RDPASALDESLERLGLDYVDLFLIHWPVPLKPVGGPENL 125
+ REE+F+T+KLW+ D AL+++L+ L +DYVDL+LIHWP LK E+L
Sbjct: 65 GFVKREELFITSKLWSNDHLPEDVPKALEKTLQDLQIDYVDLYLIHWPASLKK----ESL 120
Query: 126 LKYPTPGIKPQIDTEDWSFIKTWELMQTLPKTGKTRAVGVSNFSIKNLEDLLNSSPDVLV 185
+ P KP I + TW+ M+ L +GK RA+GVSNFS K L DLLN + +
Sbjct: 121 MPTPEMLTKPDITS-------TWKAMEALYDSGKARAIGVSNFSSKKLTDLLNVAR--VT 171
Query: 186 PAVNQFEIHPQLPQTELINYCKSKGIVVEAYCPLGSSSSA-----MLSDPTIAEIADKYH 240
PAVNQ E HP Q L CKSKG+ + Y PLGS S +L +P + E+A+K
Sbjct: 172 PAVNQVECHPVWQQQGLHELCKSKGVHLSGYSPLGSQSKGEVRLKVLQNPIVTEVAEKLG 231
Query: 241 VKPANVLINWGISRGYCVLPKSFTPARIASN 271
A V + WG+ G+ VLPKS + AR+ N
Sbjct: 232 KTTAQVALRWGLQTGHSVLPKSSSGARLKEN 262
>At2g37790 [R] KOG1577 Aldo/keto reductase family proteins
Length = 350
Score = 199 bits (507), Expect = 3e-51
Identities = 121/279 (43%), Positives = 158/279 (56%), Gaps = 30/279 (10%)
Query: 7 EFPSLKLNTGASIPQLGFGTWPSSHADAYTAVITALKTGYRHIDAAAMYGNEAAVG---K 63
E +LNTGA IP +G GTW + AV A+K GYRHID A +YGNE +G K
Sbjct: 4 EIRFFELNTGAKIPSVGLGTWQADPGLVGNAVDAAVKIGYRHIDCAQIYGNEKEIGLVLK 63
Query: 64 GIRDSG-IPREEIFVTTKLWNT--QQRDPASALDESLERLGLDYVDLFLIHWPVPLKPVG 120
+ D G + REE+F+T+KLW T ++ AL+ +L+ L LDYVDL+LIHWPV LK
Sbjct: 64 KLFDGGVVKREEMFITSKLWCTYHDPQEVPEALNRTLQDLQLDYVDLYLIHWPVSLKKGS 123
Query: 121 ---GPENLLKYPTPGIKPQIDTEDWSFIKTWELMQTLPKTGKTRAVGVSNFSIKNLEDLL 177
PEN+L P TW+ M++L +GK RA+GVSNFS K L DLL
Sbjct: 124 TGFKPENILPTDIP--------------STWKAMESLFDSGKARAIGVSNFSSKKLADLL 169
Query: 178 NSSPDVLVPAVNQFEIHPQLPQTELINYCKSKGIVVEAYCPLGSS-----SSAMLSDPTI 232
+ + PAVNQ E HP Q L ++CKSKG+ + Y PLGS +S +L +P +
Sbjct: 170 VVAR--VPPAVNQVECHPSWQQNVLRDFCKSKGVHLSGYSPLGSPGTTWLTSDVLKNPIL 227
Query: 233 AEIADKYHVKPANVLINWGISRGYCVLPKSFTPARIASN 271
+A+K PA V + WG+ G VLPKS RI N
Sbjct: 228 GGVAEKLGKTPAQVALRWGLQMGQSVLPKSTHEDRIKQN 266
>SPAC26F1.07 [R] KOG1577 Aldo/keto reductase family proteins
Length = 321
Score = 199 bits (505), Expect = 6e-51
Identities = 125/314 (39%), Positives = 176/314 (55%), Gaps = 36/314 (11%)
Query: 13 LNTGASIPQLGFGTWPSSHADAYTAVITALKTGYRHIDAAAMYGNEAAVGKGIRDSGIPR 72
L G+ IP LG GTW S AV TAL+ GYRHIDAAA+YGNE VG GI++SG+PR
Sbjct: 18 LADGSKIPGLGLGTWRSEPNQTKNAVKTALQYGYRHIDAAAIYGNEDEVGDGIKESGVPR 77
Query: 73 EEIFVTTKLWNTQQRDPA--SALDESLERLGLDYVDLFLIHWPVPLK------PVGGPEN 124
++I+VT+KLW A AL+++L+ L LDY+D +LIHWPV K P N
Sbjct: 78 KDIWVTSKLWCNAHAPEAVPKALEKTLKDLKLDYLDEYLIHWPVSFKTGEDKFPKDKDGN 137
Query: 125 LLKYPTPGIKPQIDTEDWSFIKTWELMQTLPKTGKTRAVGVSNFSIKNLEDLLNSSPDVL 184
L+ P +TW+ M+ L +TGK R +G+SNF+ NLE +L + +
Sbjct: 138 LIYEKNP------------IEETWKAMEKLLETGKVRHIGLSNFNDTNLERILKVAK--V 183
Query: 185 VPAVNQFEIHPQLPQTELINYCKSKGIVVEAYCPLGSSSS-------AMLSDPTIAEIAD 237
PAV+Q E+HP LPQTE + K GI V AY P G+ ++ ++ TI +IA
Sbjct: 184 KPAVHQMELHPFLPQTEFVEKHKKLGIHVTAYSPFGNQNTIYESKIPKLIEHETIQKIAK 243
Query: 238 K--YHVKPANVLINWGISRGYCVLPKSFTPARIASNKTPVHLSREDTERITKLSETLGVK 295
V A + ++W I+RG V+PKS RI SN + L++ED + I ++G++
Sbjct: 244 SKGEGVTGATIAVSWAITRGTSVIPKSVNEQRIKSNFKYIPLTKEDMDEI----NSIGIR 299
Query: 296 -RYVHPDFEPYPLF 308
R+ F P+F
Sbjct: 300 ARFNQATFSNEPVF 313
>Hs5174391 [R] KOG1577 Aldo/keto reductase family proteins
Length = 325
Score = 194 bits (494), Expect = 1e-49
Identities = 106/274 (38%), Positives = 159/274 (57%), Gaps = 23/274 (8%)
Query: 13 LNTGASIPQLGFGTWPSSHADAYTAVITALKTGYRHIDAAAMYGNEAAVGKGIRD----- 67
L+TG +P +G GTW S AV AL GYRHID AA+YGNE +G+ +++
Sbjct: 8 LHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPG 67
Query: 68 SGIPREEIFVTTKLWNTQQ--RDPASALDESLERLGLDYVDLFLIHWPVPLKPVGGPENL 125
+PREE+FVT+KLWNT+ D AL ++L L L+Y+DL+L+HWP + P
Sbjct: 68 KAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNP--- 124
Query: 126 LKYPTPGIKPQIDTEDWSFIKTWELMQTLPKTGKTRAVGVSNFSIKNLEDLLNSSPDVLV 185
+P I + + +TW+ ++ L G +A+G+SNF+ + ++D+L+ + +
Sbjct: 125 --FP-KNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVAS--VR 179
Query: 186 PAVNQFEIHPQLPQTELINYCKSKGIVVEAYCPLGSSSSA--------MLSDPTIAEIAD 237
PAV Q E HP L Q ELI +C+++G+ V AY PLGSS A +L +P + +A+
Sbjct: 180 PAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPDEPVLLEEPVVLALAE 239
Query: 238 KYHVKPANVLINWGISRGYCVLPKSFTPARIASN 271
KY PA +L+ W + R +PKS TP+RI N
Sbjct: 240 KYGRSPAQILLRWQVQRKVICIPKSITPSRILQN 273
>Hs4502049 [R] KOG1577 Aldo/keto reductase family proteins
Length = 316
Score = 193 bits (491), Expect = 2e-49
Identities = 117/275 (42%), Positives = 149/275 (53%), Gaps = 20/275 (7%)
Query: 11 LKLNTGASIPQLGFGTWPSSHADAYTAVITALKTGYRHIDAAAMYGNEAAVGKGI----R 66
L LN GA +P LG GTW S AV A+ GYRHID A +Y NE VG I R
Sbjct: 5 LLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 64
Query: 67 DSGIPREEIFVTTKLWNTQQRDPA--SALDESLERLGLDYVDLFLIHWPVPLKPVGGPEN 124
+ + REE+F+ +KLW T A ++L L LDY+DL+LIHWP KP G E
Sbjct: 65 EQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKP--GKEF 122
Query: 125 LLKYPTPGIKPQIDTEDWSFIKTWELMQTLPKTGKTRAVGVSNFSIKNLEDLLNSSPDVL 184
+ + P D + + TW M+ L G +A+G+SNF+ +E +LN
Sbjct: 123 FPLDESGNVVPS----DTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKY 178
Query: 185 VPAVNQFEIHPQLPQTELINYCKSKGIVVEAYCPLGS--------SSSAMLSDPTIAEIA 236
PAVNQ E HP L Q +LI YC+SKGIVV AY PLGS ++L DP I IA
Sbjct: 179 KPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIA 238
Query: 237 DKYHVKPANVLINWGISRGYCVLPKSFTPARIASN 271
K++ A VLI + + R V+PKS TP RIA N
Sbjct: 239 AKHNKTTAQVLIRFPMQRNLVVIPKSVTPERIAEN 273
>At5g62420 [R] KOG1577 Aldo/keto reductase family proteins
Length = 316
Score = 187 bits (475), Expect = 2e-47
Identities = 107/283 (37%), Positives = 161/283 (56%), Gaps = 21/283 (7%)
Query: 12 KLNTGASIPQLGFGTW--PSSHADAYTAVITALKTGYRHIDAAAMYGNE----AAVGKGI 65
+L G +IP LG GT+ +AV A+K GYRH D A +YG+E A+G+ I
Sbjct: 7 RLRCGETIPLLGMGTYCPQKDRESTISAVHQAIKIGYRHFDTAKIYGSEEALGTALGQAI 66
Query: 66 RDSGIPREEIFVTTKLWNTQQRDPASALDESLERLGLDYVDLFLIHWPVPLKPVGGPENL 125
+ R+++FVT+KLW++ DP SAL ++L+ +GLDY+D +L+HWP+ LKP
Sbjct: 67 SYGTVQRDDLFVTSKLWSSDHHDPISALIQTLKTMGLDYLDNYLVHWPIKLKPG------ 120
Query: 126 LKYPTPGIKPQIDTEDWSFIKTWELMQTLPKTGKTRAVGVSNFSIKNLEDLLNSSPDVLV 185
+ P P K +D +TW+ M+ + G R++GVSNFS K + DLL+ + +
Sbjct: 121 VSEPIP--KEDEFEKDLGIEETWQGMERCLEMGLCRSIGVSNFSSKKIFDLLDFAS--VS 176
Query: 186 PAVNQFEIHPQLPQTELINYCKSKGIVVEAYCPLGS-----SSSAMLSDPTIAEIADKYH 240
P+VNQ E+HP Q +L C+ I V Y PLG S+A++ P I IA K++
Sbjct: 177 PSVNQVEMHPLWRQRKLRKVCEENNIHVSGYSPLGGPGNCWGSTAVIEHPIIKSIALKHN 236
Query: 241 VKPANVLINWGISRGYCVLPKSFTPARIASNKTPVHLSREDTE 283
PA V + WG+S+G V+ KSF AR+ NK + + +D +
Sbjct: 237 ATPAQVALRWGMSKGASVIVKSFNGARMIENKRALEIKLDDQD 279
>YBR149w [R] KOG1577 Aldo/keto reductase family proteins
Length = 344
Score = 186 bits (472), Expect = 4e-47
Identities = 110/296 (37%), Positives = 168/296 (56%), Gaps = 16/296 (5%)
Query: 13 LNTGASIPQLGFGTWPSSH---ADAYTAVITALKTGYRHIDAAAMYGNEAAVGKGIR--- 66
LN G IP LG GT + H A+ AV A+K GYRHID A Y E VG+ I+
Sbjct: 27 LNNGVRIPALGLGT-ANPHEKLAETKQAVKAAIKAGYRHIDTAWAYETEPFVGEAIKELL 85
Query: 67 -DSGIPREEIFVTTKLWNTQQRDPASALDESLERLGLDYVDLFLIHWPVPLKPVGGPEN- 124
D I RE++F+TTK+W + +L+ESL+ LGL+YVDL L HWP+ + + P+
Sbjct: 86 EDGSIKREDLFITTKVWPVLWDEVDRSLNESLKALGLEYVDLLLQHWPLCFEKIKDPKGI 145
Query: 125 --LLKYPTPGIKPQIDTEDWSFIKTWELMQTL---PKTGKTRAVGVSNFSIKNLEDLLNS 179
L+K P + D +++T++ ++ + P + RA+GVSNFSI+ LE L+
Sbjct: 146 SGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLDPNDHRVRAIGVSNFSIEYLERLIKE 205
Query: 180 SPDVLVPAVNQFEIHPQLPQTELINYCKSKGIVVEAYCPLGSSSSAMLSDPTIAEIADKY 239
+ P VNQ E HP LPQ EL +C I++ AY PLGS + L P + ++A+KY
Sbjct: 206 CR--VKPTVNQVETHPHLPQMELRKFCFMHDILLTAYSPLGSHGAPNLKIPLVKKLAEKY 263
Query: 240 HVKPANVLINWGISRGYCVLPKSFTPARIASNKTPVHLSREDTERITKLSETLGVK 295
+V ++LI++ I +G V+P+S P RI+S+ L++++ + + E V+
Sbjct: 264 NVTGNDLLISYHIRQGTIVIPRSLNPVRISSSIEFASLTKDELQELNDFGEKYPVR 319
>ECU01g0970 [R] KOG1577 Aldo/keto reductase family proteins
Length = 301
Score = 186 bits (472), Expect = 4e-47
Identities = 117/297 (39%), Positives = 163/297 (54%), Gaps = 19/297 (6%)
Query: 12 KLNTGASIPQLGFGTWP-SSHADAYTAVITALKTGYRHIDAAAMYGNEAAVG---KGIRD 67
KLN G IP +G GTW A A+ AL GYRHID A +YGNE +G K + D
Sbjct: 7 KLNNGKEIPTVGLGTWGMEDEAVLEGAIRNALSLGYRHIDTAFIYGNEKMIGNILKKLFD 66
Query: 68 SGI-PREEIFVTTKLWNTQQRDPASALDESLERLGLDYVDLFLIHWPVPLKPVGGPENLL 126
G+ R+++F+T+KLWNT P L SL L +DYVDL+LIHWPV P P+ +
Sbjct: 67 EGVVQRKDLFITSKLWNTFHGCPEDGLRRSLNDLQMDYVDLYLIHWPVTFDP--APDGTV 124
Query: 127 KYPTPGIKPQIDTEDWSFIKTWELMQTLPKTGKTRAVGVSNFSIKNLEDLLNSSPDVLVP 186
+ + G K + D + W+ M+ L G +++G+SNF N E +L + + P
Sbjct: 125 E--SCGKKYNVGKFD--AVGVWKKMEALVDLGLAKSIGISNFGKANTEKILGTCR--ICP 178
Query: 187 AVNQFEIHPQLPQTELINYCKSKGIVVEAYCPLGS---SSSAMLSDPTIAEIADKYHVKP 243
A Q E+HP L Q EL+ + KSKGI V +Y LGS SS+ + D TI IA KY P
Sbjct: 179 AAIQIELHPYLNQKELVEFMKSKGIQVISYSSLGSAPGSSAKVRDDKTIKAIAKKYGCAP 238
Query: 244 ANVLINWGISRGYCVLPKSFTPARIASNKTPVHLSREDTERITKLSETLGVKRYVHP 300
+ +++++ ++G CV+PKS + + N LSRED I L+ RYV P
Sbjct: 239 SQIILSYITAQGICVIPKSRSKEHLRENIDLKELSREDISAIDALNTG---HRYVDP 292
>Hs20127592 [R] KOG1577 Aldo/keto reductase family proteins
Length = 316
Score = 183 bits (465), Expect = 2e-46
Identities = 116/293 (39%), Positives = 152/293 (51%), Gaps = 20/293 (6%)
Query: 11 LKLNTGASIPQLGFGTWPSSHADAYTAVITALKTGYRHIDAAAMYGNEAAVGKGIRDS-- 68
++L+T A +P +G GTW S AV A+ GYRHID A +Y NE VG+ I++
Sbjct: 5 VELSTKAKMPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQ 64
Query: 69 --GIPREEIFVTTKLWNTQQRDPA--SALDESLERLGLDYVDLFLIHWPVPLKPVGGPEN 124
+ RE++F+ +KLW T P A +++L+ L L Y+D++LIHWP K ++
Sbjct: 65 EKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFK---SGDD 121
Query: 125 LLKYPTPGIKPQIDTEDWSFIKTWELMQTLPKTGKTRAVGVSNFSIKNLEDLLNSSPDVL 184
L G +F+ WE M+ L G +A+GVSNFS +E LLN
Sbjct: 122 LFPKDDKG---NAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKY 178
Query: 185 VPAVNQFEIHPQLPQTELINYCKSKGIVVEAYCPLGS--------SSSAMLSDPTIAEIA 236
P NQ E HP L Q +LI YC SKGI V AY PLGS ++L DP I EIA
Sbjct: 179 KPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIA 238
Query: 237 DKYHVKPANVLINWGISRGYCVLPKSFTPARIASNKTPVHLSREDTERITKLS 289
K+ A VLI + I R V+PKS TPARI N D E T LS
Sbjct: 239 AKHKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILS 291
>CE24243 [R] KOG1577 Aldo/keto reductase family proteins
Length = 316
Score = 183 bits (465), Expect = 2e-46
Identities = 110/293 (37%), Positives = 161/293 (54%), Gaps = 25/293 (8%)
Query: 10 SLKLNTGASIPQLGFGTWPSSHADAYTAVITALKTGYRHIDAAAMYGNEAAVG---KGIR 66
SLKLN+G SIP +G GTW S + A+ TA+ GYRHID A +Y N+ VG K I
Sbjct: 4 SLKLNSGYSIPAIGLGTWQSKPGEVAAAIKTAVAAGYRHIDCAHVYQNQKEVGEALKEIL 63
Query: 67 DSG-IPREEIFVTTKLWNT--QQRDPASALDESLERLGLDYVDLFLIHWPVPLKPVGGPE 123
D G + REE+F+T+K+WNT + +D L L L YVDL LIHW P G E
Sbjct: 64 DEGKVKREELFITSKVWNTFHSEAKAHENIDIILSDLQLSYVDLMLIHW-----PQGYAE 118
Query: 124 NLLKYPTPGIKPQIDTEDWSFIKTWELMQTLPKTGKTRAVGVSNFSIKNLEDLLNSSPDV 183
+P G ++ D +++TW+ + K GK R++G+SNF+ ++ + +++
Sbjct: 119 GAELFPA-GENGKMRYSDVDYLETWKAFEAAQKAGKCRSIGLSNFTHSQIQRVWDAAE-- 175
Query: 184 LVPAVNQFEIHPQLPQTELINYCKSKGIVVEAYCPLGSSSSA---------MLSDPTIAE 234
+ PA Q E+HP Q +L +CK KGIVV Y PLG+ SA +L++ +A
Sbjct: 176 VKPACLQVELHPYFTQVKLREFCKEKGIVVVGYSPLGNPGSAFFRKDGDPNVLTNEVVAG 235
Query: 235 IADKYHVKPANVLINWGISRGYCVLPKSFTPARIASNKTPV--HLSREDTERI 285
IA + PA +++ W + G +PKS TP RI N + + LS E+ + I
Sbjct: 236 IAKAHGKTPAQIILRWFVDSGLSAIPKSVTPQRIIENISVIDFQLSAEEIQAI 288
>7294702 [R] KOG1577 Aldo/keto reductase family proteins
Length = 302
Score = 183 bits (464), Expect = 3e-46
Identities = 107/277 (38%), Positives = 151/277 (53%), Gaps = 22/277 (7%)
Query: 9 PSLKLNTGASIPQLGFGTWPSSHADAYTAVITALKTGYRHIDAAAMYGNEAAVGKG---- 64
P++K N G +P +G GTW S AV A+ GYRHID A +Y NE VG G
Sbjct: 4 PNVKFNNGKEVPIIGLGTWGSPKGQVTEAVKVAIDAGYRHIDCAYVYQNEDEVGDGVEAK 63
Query: 65 IRDSGIPREEIFVTTKLWNTQQRDP--ASALDESLERLGLDYVDLFLIHWPVPLKPVGGP 122
I++ + RE++F+T+KLWNT R SAL+ +L L L Y+DL+LIHW P+G
Sbjct: 64 IKEGVVKREDLFITSKLWNTFHRPDLVKSALENTLSSLKLKYLDLYLIHW-----PMGYK 118
Query: 123 ENLLKYPTPGIKPQIDTEDWSFIKTWELMQTLPKTGKTRAVGVSNFSIKNLEDLLNSSPD 182
E +PT + ++ TW+ M+ L + G +++GVSNF+ + +E +L +
Sbjct: 119 EGCDLFPTDKDGKTL-YSPVDYVDTWKAMEKLVEEGLVKSIGVSNFNRRQIERVLEVA-- 175
Query: 183 VLVPAVNQFEIHPQLPQTELINYCKSKGIVVEAYCPLGS--------SSSAMLSDPTIAE 234
+ P NQ E HP L Q +LI++CKSK I + AY PLGS +L + I E
Sbjct: 176 TIPPVTNQIECHPYLTQKKLIDFCKSKDITITAYSPLGSPNRPWAKAGDPVILEEAKIKE 235
Query: 235 IADKYHVKPANVLINWGISRGYCVLPKSFTPARIASN 271
IA K P +LI + + R V+PKS T RI SN
Sbjct: 236 IAAKKKKTPGQILIRYQVQRANIVIPKSVTKDRIESN 272
>CE21733 [R] KOG1577 Aldo/keto reductase family proteins
Length = 316
Score = 182 bits (463), Expect = 4e-46
Identities = 106/277 (38%), Positives = 154/277 (55%), Gaps = 23/277 (8%)
Query: 10 SLKLNTGASIPQLGFGTWPSSHADAYTAVITALKTGYRHIDAAAMYGNEAAVG---KGIR 66
SLKLN+G SIP +G GTW S + A+ TA+ GYRHID A +Y N+ VG K I
Sbjct: 4 SLKLNSGYSIPAIGLGTWQSKPGEVAAAIKTAVAAGYRHIDCAHVYQNQKEVGEALKEIL 63
Query: 67 DSG-IPREEIFVTTKLWNT--QQRDPASALDESLERLGLDYVDLFLIHWPVPLKPVGGPE 123
D G + REE+F+T+K+WNT + +D L L L YVDL LIHW P G E
Sbjct: 64 DEGKVKREELFITSKVWNTFHSEAKAHENIDIILSDLQLSYVDLMLIHW-----PQGYAE 118
Query: 124 NLLKYPTPGIKPQIDTEDWSFIKTWELMQTLPKTGKTRAVGVSNFSIKNLEDLLNSSPDV 183
+P G ++ D +++TW+ + K GK R++G+SNF+ ++ + +++
Sbjct: 119 GAELFPA-GENGKMRYSDVDYLETWKAFEAAQKAGKCRSIGLSNFTHSQIQRVWDAAE-- 175
Query: 184 LVPAVNQFEIHPQLPQTELINYCKSKGIVVEAYCPLGSSSSA---------MLSDPTIAE 234
+ PA Q E+HP Q +L +CK KGIVV Y PLG+ SA +L++ +A
Sbjct: 176 VKPACLQVELHPYFTQVKLREFCKEKGIVVVGYSPLGNPGSAFFRKDGDPNVLTNEVVAG 235
Query: 235 IADKYHVKPANVLINWGISRGYCVLPKSFTPARIASN 271
IA + PA +++ W + G +PKS TP RI+ N
Sbjct: 236 IAKAHGKTPAQIILRWFVDSGLSAIPKSVTPQRISEN 272
>At2g21250 [R] KOG1577 Aldo/keto reductase family proteins
Length = 309
Score = 179 bits (454), Expect = 5e-45
Identities = 105/292 (35%), Positives = 155/292 (52%), Gaps = 18/292 (6%)
Query: 11 LKLNTGASIPQLGFGTWPSSHADAYTAVITALKTGYRHIDAAAMYGNEAAVGKGIRDSG- 69
+ LN+G +P +G G W ++ A+K GYRH+D AA Y NE VG + ++
Sbjct: 3 ITLNSGFKMPIVGLGVWRMEKEGIRDLILNAIKIGYRHLDCAADYRNETEVGDALTEAFK 62
Query: 70 ---IPREEIFVTTKLWNTQQRDPASALDESLERLGLDYVDLFLIHWPVPLKPVGGPENLL 126
+ RE++F+TTKLWN+ A +SL++L LDY+DLFL+H+PV K G
Sbjct: 63 TGLVKREDLFITTKLWNSDHGHVIEACKDSLKKLQLDYLDLFLVHFPVATKHTGVGTTDS 122
Query: 127 KYPTPGIKPQIDTEDWSFIKTWELMQTLPKTGKTRAVGVSNFSIKNLEDLLNSSPDVLVP 186
G+ IDT S TW M+ L G R++G+SN+ + D L S + P
Sbjct: 123 ALGDDGVL-DIDT-TISLETTWHDMEKLVSMGLVRSIGISNYDVFLTRDCLAYSK--IKP 178
Query: 187 AVNQFEIHPQLPQTELINYCKSKGIVVEAYCPLGSSSS--------AMLSDPTIAEIADK 238
AVNQ E HP + L+ +C+ GI V A+ PLG +++ + L DP + ++A+K
Sbjct: 179 AVNQIETHPYFQRDSLVKFCQKHGICVTAHTPLGGATANAEWFGTVSCLDDPVLKDVAEK 238
Query: 239 YHVKPANVLINWGISRGYCVLPKSFTPARIASN--KTPVHLSREDTERITKL 288
Y A V++ WGI R V+PK+ PAR+ N LS+ED E I +
Sbjct: 239 YKKTVAQVVLRWGIQRKTVVIPKTSKPARLEENFQVFDFELSKEDMEVIKSM 290
>7292407 [R] KOG1577 Aldo/keto reductase family proteins
Length = 320
Score = 179 bits (454), Expect = 5e-45
Identities = 109/271 (40%), Positives = 151/271 (55%), Gaps = 17/271 (6%)
Query: 12 KLNTGASIPQLGFGTWPSSHADAYTAVITALKTGYRHIDAAAMYGNEAAVGKGIR----D 67
K N G I +G GT+ S+ D AV+ A+ GYRHID A YGNEA VG +R +
Sbjct: 10 KHNDGTHIQGIGLGTFASTEGDCERAVLHAIDVGYRHIDTAYFYGNEAEVGAAVRKKIAE 69
Query: 68 SGIPREEIFVTTKLW-NTQQRDPAS-ALDESLERLGLDYVDLFLIHWPVPLKPVGGPENL 125
I RE+IF+TTKLW N + + A ++L+ +GLDYVDL+LIHWP K G E +
Sbjct: 70 GVIKREDIFITTKLWCNFHEPERVEYACRKTLKNIGLDYVDLYLIHWPFSYKYRGDNELI 129
Query: 126 LKYPTPGIKPQIDTEDWSFIKTWELMQTLPKTGKTRAVGVSNFSIKNLEDLLNSSPDVLV 185
K +++ D ++ TW M+ L G T+++GVSNF+ + L LL + +
Sbjct: 130 PK----DANGEVELVDIDYLDTWGAMEKLVDLGLTKSIGVSNFNEEQLTRLLANCK--IK 183
Query: 186 PAVNQFEIHPQLPQTELINYCKSKGIVVEAYCPLGSSSSAM-----LSDPTIAEIADKYH 240
P NQ E+HP L Q +LI CK GI+V A+ PLG ++ + + D + IADKY+
Sbjct: 184 PIHNQIEVHPALDQKKLIALCKKNGILVTAFSPLGRHNAELRTPTFMYDGKVQAIADKYN 243
Query: 241 VKPANVLINWGISRGYCVLPKSFTPARIASN 271
A V+I + I G LPKS P RI N
Sbjct: 244 KSIAQVVIRYVIELGTIPLPKSSNPKRIEEN 274
>At2g21260 [R] KOG1577 Aldo/keto reductase family proteins
Length = 309
Score = 178 bits (451), Expect = 1e-44
Identities = 103/292 (35%), Positives = 156/292 (53%), Gaps = 18/292 (6%)
Query: 11 LKLNTGASIPQLGFGTWPSSHADAYTAVITALKTGYRHIDAAAMYGNEAAVGKGIRDSG- 69
+ LN+G +P +G G W + +I A+K GYRH+D AA Y NEA VG+ + ++
Sbjct: 3 ITLNSGFKMPIIGLGVWRMEKEELRDLIIDAIKIGYRHLDCAANYKNEAEVGEALTEAFT 62
Query: 70 ---IPREEIFVTTKLWNTQQRDPASALDESLERLGLDYVDLFLIHWPVPLKPVGGPENLL 126
+ RE++F+TTKLW++ A +SL++L LDY+DLFL+H P+ K G
Sbjct: 63 TGLVKREDLFITTKLWSSDHGHVIEACKDSLKKLQLDYLDLFLVHIPIATKHTGIGTTDS 122
Query: 127 KYPTPGIKPQIDTEDWSFIKTWELMQTLPKTGKTRAVGVSNFSIKNLEDLLNSSPDVLVP 186
G+ IDT S TW M+ L G R++G+SN+ + D L S + P
Sbjct: 123 ALGDDGVL-DIDT-TISLETTWHDMEKLVSMGLVRSIGISNYDVFLTRDCLAYSK--IKP 178
Query: 187 AVNQFEIHPQLPQTELINYCKSKGIVVEAYCPLGSSSS--------AMLSDPTIAEIADK 238
AVNQ E HP + L+ +C+ GI V A+ PLG +++ + L DP + ++A+K
Sbjct: 179 AVNQIETHPYFQRDSLVKFCQKHGICVTAHTPLGGATANAEWFGTVSCLDDPVLKDVAEK 238
Query: 239 YHVKPANVLINWGISRGYCVLPKSFTPARIASN--KTPVHLSREDTERITKL 288
Y A +++ WGI R V+PK+ P R+ N LS+ED E I +
Sbjct: 239 YKQTVAQIVLRWGIQRNTVVIPKTSKPERLEENFQVFDFQLSKEDMEVIKSM 290
>At5g01670 [R] KOG1577 Aldo/keto reductase family proteins
Length = 320
Score = 177 bits (449), Expect = 2e-44
Identities = 104/277 (37%), Positives = 146/277 (52%), Gaps = 21/277 (7%)
Query: 2 TSPSGEFPSLKLNTGASIPQLGFGTWPSSHADAYTAVITALKTGYRHIDAAAMYGNEAAV 61
TS S +L +G IP +G GTW S A+ V ++ GYRHID A YG++ V
Sbjct: 7 TSEGQNMESFRLLSGHKIPAVGLGTWRSGSQAAHAVVTAIVEGGYRHIDTAWEYGDQREV 66
Query: 62 GKGIR---DSGIPREEIFVTTKLWNTQ--QRDPASALDESLERLGLDYVDLFLIHWPVPL 116
G+GI+ +G+ R ++FVT+KLW T+ AL +L+ L L+Y+DL+LIHWP+ L
Sbjct: 67 GQGIKRAMHAGLERRDLFVTSKLWCTELSPERVRPALQNTLKELQLEYLDLYLIHWPIRL 126
Query: 117 KPVGGPENLLKYPTPGIKPQIDTEDWSFIKTWELMQTLPKTGKTRAVGVSNFSIKNLEDL 176
+ E K P G D D+ W M+ L K R +GV NF++ L L
Sbjct: 127 R-----EGASKPPKAG-----DVLDFDMEGVWREMENLSKDSLVRNIGVCNFTVTKLNKL 176
Query: 177 LNSSPDVLVPAVNQFEIHPQLPQTELINYCKSKGIVVEAYCPLGSSSSA--MLSDPTIAE 234
L + L+PAV Q E+HP ++ +CK I AY PLGS ++ D T+
Sbjct: 177 LGFAE--LIPAVCQMEMHPGWRNDRILEFCKKNEI--HAYSPLGSQEGGRDLIHDQTVDR 232
Query: 235 IADKYHVKPANVLINWGISRGYCVLPKSFTPARIASN 271
IA K + P +L+ WG+ RG V+PKS P RI N
Sbjct: 233 IAKKLNKTPGQILVKWGLQRGTSVIPKSLNPERIKEN 269
>Hs11386205 [R] KOG1577 Aldo/keto reductase family proteins
Length = 323
Score = 177 bits (448), Expect = 2e-44
Identities = 119/316 (37%), Positives = 171/316 (53%), Gaps = 29/316 (9%)
Query: 7 EFPSLKLNTGASIPQLGFGTWPSSHADAYTAVIT---ALKTGYRHIDAAAMYGNEAAVGK 63
++ ++LN G +P LGFGT+ AV A++ G+RHID+A +Y NE VG
Sbjct: 4 KYQRVELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGL 63
Query: 64 GIR----DSGIPREEIFVTTKLWNT--QQRDPASALDESLERLGLDYVDLFLIHWPVPLK 117
IR D + RE+IF T+KLW T Q + AL+ SL++L LDYVDL+L+H+P+ LK
Sbjct: 64 AIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALK 123
Query: 118 PVGGPENLLKYPTPGIKPQIDTEDWSFIKTWELMQTLPKTGKTRAVGVSNFSIKNLEDLL 177
P P L G K DT D S TWE+M+ G +++GVSNF+ + LE +L
Sbjct: 124 PGETP---LPKDENG-KVIFDTVDLS--ATWEVMEKCKDAGLAKSIGVSNFNCRQLEMIL 177
Query: 178 NSSPDVLVPAVNQFEIHPQLPQTELINYCKSKGIVVEAYCPLGS---------SSSAMLS 228
N P NQ E HP L Q++L+++CKSK IV+ A+ LG+ +S +L
Sbjct: 178 NKPGLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQRHKLWVDPNSPVLLE 237
Query: 229 DPTIAEIADKYHVKPANVLINWGISRGYCVLPKSFTPARIASN--KTPVHLSREDTERIT 286
DP + +A K+ PA + + + + RG VL KS+ RI N L+ ED + +
Sbjct: 238 DPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRENIQVFEFQLTSEDMKVLD 297
Query: 287 KLSETLGVKRYVHPDF 302
L+ RYV DF
Sbjct: 298 GLNRNY---RYVVMDF 310
>Hs4503285 [R] KOG1577 Aldo/keto reductase family proteins
Length = 323
Score = 176 bits (445), Expect = 5e-44
Identities = 110/283 (38%), Positives = 155/283 (53%), Gaps = 24/283 (8%)
Query: 7 EFPSLKLNTGASIPQLGFGTWPSSH---ADAYTAVITALKTGYRHIDAAAMYGNEAAVGK 63
++ +KLN G +P LGFGT+ + + A AV A++ G+ HID+A +Y NE VG
Sbjct: 4 KYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGL 63
Query: 64 GIR----DSGIPREEIFVTTKLWNTQQRDPA--SALDESLERLGLDYVDLFLIHWPVPLK 117
IR D + RE+IF T+KLW+ R AL+ SL+ L LDYVDL+LIH+PV +K
Sbjct: 64 AIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVK 123
Query: 118 PVGGPENLLKYPTPGIKPQIDTEDWSFIKTWELMQTLPKTGKTRAVGVSNFSIKNLEDLL 177
P E ++ G K DT D TWE M+ G +++GVSNF+ + LE +L
Sbjct: 124 P---GEEVIPKDENG-KILFDTVD--LCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMIL 177
Query: 178 NSSPDVLVPAVNQFEIHPQLPQTELINYCKSKGIVVEAYCPLGS---------SSSAMLS 228
N P NQ E HP Q +L+++CKSK IV+ AY LGS +S +L
Sbjct: 178 NKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLE 237
Query: 229 DPTIAEIADKYHVKPANVLINWGISRGYCVLPKSFTPARIASN 271
DP + +A K+ PA + + + + RG VL KS+ RI N
Sbjct: 238 DPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQN 280
>Hs5453543 [R] KOG1577 Aldo/keto reductase family proteins
Length = 323
Score = 174 bits (442), Expect = 1e-43
Identities = 109/283 (38%), Positives = 154/283 (53%), Gaps = 24/283 (8%)
Query: 7 EFPSLKLNTGASIPQLGFGTWPSSH---ADAYTAVITALKTGYRHIDAAAMYGNEAAVGK 63
++ +KLN G +P LGFGT+ + + A A A++ G+RHID+A +Y NE VG
Sbjct: 4 KYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGL 63
Query: 64 GIR----DSGIPREEIFVTTKLWNTQQRDPA--SALDESLERLGLDYVDLFLIHWPVPLK 117
IR D + RE+IF T+KLW R AL+ SL+ L LDYVDL+LIH+PV +K
Sbjct: 64 AIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVK 123
Query: 118 PVGGPENLLKYPTPGIKPQIDTEDWSFIKTWELMQTLPKTGKTRAVGVSNFSIKNLEDLL 177
P E ++ G K DT D TWE ++ G +++GVSNF+ + LE +L
Sbjct: 124 P---GEEVIPKDENG-KILFDTVD--LCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMIL 177
Query: 178 NSSPDVLVPAVNQFEIHPQLPQTELINYCKSKGIVVEAYCPLGS---------SSSAMLS 228
N P NQ E HP Q +L+++CKSK IV+ AY LGS +S +L
Sbjct: 178 NKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLE 237
Query: 229 DPTIAEIADKYHVKPANVLINWGISRGYCVLPKSFTPARIASN 271
DP + +A K+ PA + + + + RG VL KS+ RI N
Sbjct: 238 DPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQN 280
>Hs13899261 [R] KOG1577 Aldo/keto reductase family proteins
Length = 307
Score = 174 bits (442), Expect = 1e-43
Identities = 110/298 (36%), Positives = 154/298 (50%), Gaps = 25/298 (8%)
Query: 19 IPQLGFGTWPSSHADAYTAVITALKTGYRHIDAAAMYGNEAAVGKGIR----DSGIPREE 74
IP +G +W +S AV A+ GYRH D A Y NE VG GIR + + RE+
Sbjct: 4 IPAVGLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRRED 63
Query: 75 IFVTTKLWNTQQRDPA--SALDESLERLGLDYVDLFLIHWPVPLKPVGGPENL------- 125
+F+ TKLW T + +A +SL+ L L+Y+DL+LIHWP+ KP PE +
Sbjct: 64 LFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKPPH-PEWIMSCSELS 122
Query: 126 --LKYPTPGIKP-----QIDTEDWSFIKTWELMQTLPKTGKTRAVGVSNFSIKNLEDLLN 178
L +P P + D F+ TWE M+ L TG + +GVSNF+ + LE LLN
Sbjct: 123 FCLSHPRVQDLPLDESNMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLN 182
Query: 179 SSPDVLVPAVNQFEIHPQLPQTELINYCKSKGIVVEAYCPLGSSSSA--MLSDPTIAEIA 236
P NQ E HP L Q LI++C+S+ + V AY PLG S ++ +P I IA
Sbjct: 183 KPGLRFKPLTNQIECHPYLTQKNLISFCQSRDVSVTAYRPLGGSCEGVDLIDNPVIKRIA 242
Query: 237 DKYHVKPANVLINWGISRGYCVLPKSFTPARIASN--KTPVHLSREDTERITKLSETL 292
++ PA +LI + I R V+P S TP+ I N L++ D + I L+ L
Sbjct: 243 KEHGKSPAQILIRFQIQRNVIVIPGSITPSHIKENIQVFDFELTQHDMDNILSLNRNL 300
>7294701 [R] KOG1577 Aldo/keto reductase family proteins
Length = 305
Score = 172 bits (436), Expect = 6e-43
Identities = 109/297 (36%), Positives = 156/297 (51%), Gaps = 23/297 (7%)
Query: 9 PSLKLNTGASIPQLGFGTWPSSHADAYTAVITALKTGYRHIDAAAMYGNEAAVGKGIR-- 66
P+ L+ G ++P LG GTW S AV A+ GYRH D A +YGNEA VG +R
Sbjct: 4 PNFLLSNGKNMPMLGLGTWRSPPEVVTQAVKDAIDIGYRHFDCAHIYGNEAQVGAALREK 63
Query: 67 -DSG-IPREEIFVTTKLWNTQQRDP--ASALDESLERLGLDYVDLFLIHWPVPLKPVGGP 122
D G + R+E+F+T+KLWNT + A + S+ LG+ Y++L+L+HWP+ K G
Sbjct: 64 MDEGVVTRDELFITSKLWNTHHKPDLVRPACETSIRNLGVKYLNLYLMHWPMAYK--SGS 121
Query: 123 ENLLKYPTPGIKPQIDTEDWSFIKTWELMQTLPKTGKTRAVGVSNFSIKNLEDLLNSSPD 182
+NL YPT + ED ++ TW M+ L G +A+GVSNF+ + + LL+ +
Sbjct: 122 DNL--YPTCPDTNKAAFEDIDYVDTWRAMENLVDEGLCQAIGVSNFNEQQMNRLLSVAK- 178
Query: 183 VLVPAVNQFEIHPQLPQTELINYCKSKGIVVEAYCPLGSSSS--------AMLSDPTIAE 234
L P V Q E HP L Q LI C I V AY LGS + +L PTI
Sbjct: 179 -LKPVVLQIECHPYLSQKPLITLCYDNAIAVTAYSCLGSGHTPYEKPGAYPLLQHPTILA 237
Query: 235 IADKYHVKPANVLINWGISRGYCVLPKSFTPARIASNKTPV---HLSREDTERITKL 288
IA+KY A VL+ + G V+P+S + + N + L+ +D + I +L
Sbjct: 238 IAEKYERTAAQVLLRFQTQSGIIVIPRSVSKQHMLDNFKRIWDFELAVDDIQAINEL 294
>Hs20127601 [R] KOG1577 Aldo/keto reductase family proteins
Length = 323
Score = 172 bits (435), Expect = 7e-43
Identities = 117/304 (38%), Positives = 161/304 (52%), Gaps = 30/304 (9%)
Query: 11 LKLNTGASIPQLGFGTW-----PSSHADAYTAVITALKTGYRHIDAAAMYGNEAAVGKGI 65
+KLN G +P LGFGT+ P S A T + A++ G+RHID+A +Y NE VG I
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKL--AIEAGFRHIDSAHLYNNEEQVGLAI 65
Query: 66 R----DSGIPREEIFVTTKLWNTQQRDPA--SALDESLERLGLDYVDLFLIHWPVPLKPV 119
R D + RE+IF T+KLW+T R AL+ SL++ LDYVDL+LIH P+ LKP
Sbjct: 66 RSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKP- 124
Query: 120 GGPENLLKYPTPGIKPQIDTEDWSFIKTWELMQTLPKTGKTRAVGVSNFSIKNLEDLLNS 179
E L G K D D TWE M+ G +++GVSNF+ + LE +LN
Sbjct: 125 --GEELSPTDENG-KVIFDIVD--LCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNK 179
Query: 180 SPDVLVPAVNQFEIHPQLPQTELINYCKSKGIVVEAYCPLGS---------SSSAMLSDP 230
P NQ E HP +++L+++CKSK IV+ AY LGS +S +L DP
Sbjct: 180 PGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDP 239
Query: 231 TIAEIADKYHVKPANVLINWGISRGYCVLPKSFTPARIASNKT--PVHLSREDTERITKL 288
+ +A K+ PA + + + + RG VL KS+ RI N L+ ED + I L
Sbjct: 240 VLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTAEDMKAIDGL 299
Query: 289 SETL 292
L
Sbjct: 300 DRNL 303
>SPAC2F3.05c [R] KOG1577 Aldo/keto reductase family proteins
Length = 275
Score = 171 bits (434), Expect = 9e-43
Identities = 103/301 (34%), Positives = 161/301 (53%), Gaps = 43/301 (14%)
Query: 11 LKLNTGASIPQLGFGTWPSSHADAYTAVITALKTGYRHIDAAAMYGNEAAVGKGI----R 66
+KLN G PQ +G++ + + +V AL+ GYRHID+A MY NEA G+ I
Sbjct: 6 VKLNNGLKCPQFAYGSYMVNRTKCFDSVYAALQCGYRHIDSAQMYHNEADCGRAILKFME 65
Query: 67 DSGIPREEIFVTTKLWNTQ-QRDPASALDESLERLGLDYVDLFLIHWPVPLKPVGGPENL 125
++G RE+I+ T+KL + + S++D S++ GL Y+DLFL+H P +
Sbjct: 66 ETGTKREDIWFTSKLNDLSGYKSTLSSIDASVKACGLGYIDLFLLHSPYGDR-------- 117
Query: 126 LKYPTPGIKPQIDTEDWSFIKTWELMQTLPKTGKTRAVGVSNFSIKNLEDLLNSSPDVLV 185
I++W+ ++ + GK RA+GVSNF ++++LL+S P + +
Sbjct: 118 -------------------IESWKALEKGVEEGKLRAIGVSNFGPHHIQELLDSHPKI-I 157
Query: 186 PAVNQFEIHPQLPQTELINYCKSKGIVVEAYCPLGSSSSAMLSDPTIAEIADKYHVKPAN 245
P VNQ E+HP Q ++++YC+SKGI + AY PL + + IA KY+ A
Sbjct: 158 PCVNQIELHPFCSQQKVVDYCESKGIQLAAYAPLVHGEK--FGNKQLLAIASKYNKSEAQ 215
Query: 246 VLINWGISRGYCVLPKSFTPARIASNKT--PVHLSREDTERITKLSETLGVKRYVHPDFE 303
++I + + RG+ VLPKS TP RI N +S+ED E++ L E H D+
Sbjct: 216 IMIRYCLQRGFIVLPKSSTPRRIKENGDVFDFEISKEDMEKLYNLDED------YHSDWN 269
Query: 304 P 304
P
Sbjct: 270 P 270
>7298972 [R] KOG1577 Aldo/keto reductase family proteins
Length = 329
Score = 171 bits (433), Expect = 1e-42
Identities = 113/323 (34%), Positives = 168/323 (51%), Gaps = 39/323 (12%)
Query: 11 LKLNTGASIPQLGFGTWPSSHADAYTAVITALKTGYRHIDAAAMYGNEAAVGKGIR---D 67
L N G +P +G GTW +S + TA+ AL+ GYRHID A +YGNE A+G+ ++ D
Sbjct: 7 LTFNNGEKMPVIGIGTWQASDEEIETAIDAALEAGYRHIDTAPVYGNEKAIGRVLKRWLD 66
Query: 68 SG-IPREEIFVTTKLWNTQQR--DPASALDESLERLGLDYVDLFLIHWPVPLKPVGGPEN 124
+G + REE+F+ TK+ R + + +SLE L LDYVDL+L+H P + +
Sbjct: 67 AGKVKREELFIVTKVPPVSNRPHEVEPTIKKSLEDLQLDYVDLYLVHTPFTINI--NEDG 124
Query: 125 LLKYPTPGIKPQIDTEDWSFIKTWELMQTLPKTGKTRAVGVSNFSIKNLEDLLNSSPDVL 184
K G+ T + + I W M+ L + G T+++GVSNFS + LL + +
Sbjct: 125 SFKLDKEGLMEVDVTTNHAAI--WVAMEALVEKGLTKSIGVSNFSKDQVARLLKNCK--I 180
Query: 185 VPAVNQFEIHPQLPQTELINYCKSKGIVVEAYCPLGSSSSA--------------MLSDP 230
PA NQ E H L Q +L+++CKS+ I V AY PLGS A ++ P
Sbjct: 181 RPANNQIEHHVYLQQRDLVDFCKSENITVTAYSPLGSKGIAKFNAGAGIVRDLPDLMDIP 240
Query: 231 TIAEIADKYHVKPANVLINWGISRGYCVLPKSFTPARIASNKT--PVHLSREDTERITKL 288
+ EIA + PA VL+ W I G +PKS PAR+ N L+ E+ +++ L
Sbjct: 241 EVKEIAASHGKTPAQVLLRWIIDTGVSAIPKSTNPARLKQNLDVFDFELTAEEVAKLSSL 300
Query: 289 SETL---------GVKRYVHPDF 302
+ + GV+R HP+F
Sbjct: 301 DQNIRICDFAFFHGVER--HPEF 321
>7292408 [R] KOG1577 Aldo/keto reductase family proteins
Length = 316
Score = 169 bits (429), Expect = 4e-42
Identities = 107/278 (38%), Positives = 146/278 (52%), Gaps = 17/278 (6%)
Query: 5 SGEFPSLKLNTGASIPQLGFGTWPSSHADAYTAVITALKTGYRHIDAAAMYGNE----AA 60
S + P +K N G I +G GT+ S D A + A+ GYRHID A Y NE AA
Sbjct: 2 SSKIPYVKHNNGTQIQSIGLGTYTSLGGDCERATLHAIDVGYRHIDTAYFYENENEVGAA 61
Query: 61 VGKGIRDSGIPREEIFVTTKLW--NTQQRDPASALDESLERLGLDYVDLFLIHWPVPLKP 118
V + I + I RE+I +TTKLW + + A ++L+ GL YVDL+L+HWP
Sbjct: 62 VQRKIAEGVIKREDIHITTKLWCHFHEPKRVEYACRKTLQNFGLQYVDLYLMHWPYSYVY 121
Query: 119 VGGPENLLKYPTPGIKPQIDTEDWSFIKTWELMQTLPKTGKTRAVGVSNFSIKNLEDLLN 178
G E + PT K +++ D ++ TW M+ L + G T+++GVSNF+ + L LL
Sbjct: 122 RGDNEMM---PTDA-KGEVELNDIDYLDTWREMEKLVELGLTKSIGVSNFNSEQLTRLLA 177
Query: 179 SSPDVLVPAVNQFEIHPQLPQTELINYCKSKGIVVEAYCPLGSSSSA-----MLSDPTIA 233
+ + P NQ E HP L Q +LI CK IVV AYCPLG + A + D +
Sbjct: 178 NCK--IKPIHNQIECHPALNQKKLIALCKKNDIVVTAYCPLGRPNPAEKTPNYIYDAKVQ 235
Query: 234 EIADKYHVKPANVLINWGISRGYCVLPKSFTPARIASN 271
I DKY A V++ + I G LPKS P RI N
Sbjct: 236 AIGDKYKKSTAQVVLRYLIEIGTIPLPKSSNPKRIEEN 273
>CE10936 [R] KOG1577 Aldo/keto reductase family proteins
Length = 283
Score = 163 bits (412), Expect = 3e-40
Identities = 97/284 (34%), Positives = 142/284 (49%), Gaps = 20/284 (7%)
Query: 10 SLKLNTGASIPQLGFGTWPSSHADAYTAVITALKTGYRHIDAAAMYGNEAAVGKGIR--- 66
S+KLNTG P +G GT+ + AL GYR D A +Y NE +G +
Sbjct: 2 SIKLNTGYDCPLIGLGTYKIIGDQVLPVLDAALTAGYRLFDTAKVYNNEKEIGDALEILL 61
Query: 67 -DSGIPREEIFVTTKLWNTQQRDPASALDESLERLGLDYVDLFLIHWPVPLKPVGGPENL 125
+ RE+IF+TTK+ + +DESL L Y+D++LIH+P G + +
Sbjct: 62 PKHNLKREDIFITTKMHPNTVENVKKLVDESLSLLKTSYIDMYLIHYPKSFD-YGDQDPM 120
Query: 126 LKYPTPGIKPQIDTEDWSFIKTWELMQTLPKTGKTRAVGVSNFSIKNLEDLLNSSPDVLV 185
K I TW + GK R+VGVS+F I++LE+L + +
Sbjct: 121 NKTLR--------------IATWNDLWECKNAGKIRSVGVSSFEIRHLEELKDLGKN-FP 165
Query: 186 PAVNQFEIHPQLPQTELINYCKSKGIVVEAYCPLGSSSSAMLSDPTIAEIADKYHVKPAN 245
P NQ E HP + EL NYCKS+GI +A+ L + +LS I +A+KYHV
Sbjct: 166 PCCNQVEYHPHFTREELKNYCKSEGIFFQAFSSLARHNETLLSSEIITRLAEKYHVPKTT 225
Query: 246 VLINWGISRGYCVLPKSFTPARIASNKTPVHLSREDTERITKLS 289
VL++W S+ ++PKS P R+A N V L E+ ++I L+
Sbjct: 226 VLLSWATSQKVGIIPKSTNPERLAQNLKTVLLEEEEVKKICNLN 269
>7302301 [R] KOG1577 Aldo/keto reductase family proteins
Length = 311
Score = 162 bits (410), Expect = 6e-40
Identities = 103/275 (37%), Positives = 141/275 (50%), Gaps = 24/275 (8%)
Query: 9 PSLKLNTGASIPQLGFGTWPSSHADAYTAVITALKTGYRHIDAAAMYGNEAAVGKG---- 64
P+++LN G +P LG GTW S +DAY + AL GYRH+D A +Y NEA VG+
Sbjct: 6 PTIRLNNGREMPTLGLGTWKSFESDAYHSTRHALDVGYRHLDTAFVYENEAEVGQAISEK 65
Query: 65 IRDSGIPREEIFVTTKLWNTQQRDPA---SALDESLERLGLDYVDLFLIHWPVPLKPVGG 121
I + + REE+FVTTKL DPA A SL LGL+YVDL+L+H PV K
Sbjct: 66 IAEGVVTREEVFVTTKLGGI-HHDPALVERACRLSLSNLGLEYVDLYLMHMPVGQK---- 120
Query: 122 PENLLKYPTPGIKPQIDTEDWSFIKTWELMQTLPKTGKTRAVGVSNFSIKNLEDLLNSSP 181
+ + ++ D ++ TW M+ L G TR++G+SNF+ E +L +
Sbjct: 121 -----FHNDSNVHGTLELTDVDYLDTWREMEKLVDLGLTRSIGLSNFNAAQTERVLANCR 175
Query: 182 DVLVPAVNQFEIHPQLPQTELINYCKSKGIVVEAYCPLGSSSSA-----MLSDPTIAEIA 236
+ P VNQ E HP Q +L + K G+V+ AYCPL A L D +A
Sbjct: 176 --IRPVVNQVECHPGFQQRQLREHAKRHGLVICAYCPLARPQPARQWPPFLYDEHAQNLA 233
Query: 237 DKYHVKPANVLINWGISRGYCVLPKSFTPARIASN 271
KY A + + + + G LPKS ARI N
Sbjct: 234 KKYGRTTAQICLRYLVQLGVVPLPKSSNKARIEEN 268
>YJR096w [R] KOG1577 Aldo/keto reductase family proteins
Length = 282
Score = 159 bits (401), Expect = 6e-39
Identities = 105/303 (34%), Positives = 149/303 (48%), Gaps = 46/303 (15%)
Query: 12 KLNTGASIPQLGFGTWPSSHADAYTAVITALKTGYRHIDAAAMYGNEAAVGKGI-----R 66
KL+ G IP + GT+ + V +K GYRH D A +YGNE VG GI
Sbjct: 7 KLSNGFKIPSIALGTYDIPRSQTAEIVYEGVKCGYRHFDTAVLYGNEKEVGDGIIKWLNE 66
Query: 67 DSG-IPREEIFVTTKLWNTQQ--RDPASALDESLERL-GLDYVDLFLIHWPVPLKPVGGP 122
D G REEIF TTKLWN+Q + +A+ + L + GL Y+DL LIH P+
Sbjct: 67 DPGNHKREEIFYTTKLWNSQNGYKRAKAAIRQCLNEVSGLQYIDLLLIHSPL-------- 118
Query: 123 ENLLKYPTPGIKPQIDTEDWSFIKTWELMQTLPKTGKTRAVGVSNFSIKNLEDLLNSSPD 182
G K +++ TW MQ G +++GVSN+ K++++LLN
Sbjct: 119 --------EGSKLRLE--------TWRAMQEAVDEGLVKSIGVSNYGKKHIDELLNWPEL 162
Query: 183 VLVPAVNQFEIHPQLPQTELINYCKSKGIVVEAYCPLGSSSSAMLSDPTIAEIADKYHVK 242
P VNQ EI P + + EL +YCKSKG+VVEA+ PL +++P + ++ +
Sbjct: 163 KHKPVVNQIEISPWIMRQELADYCKSKGLVVEAFAPL--CHGYKMTNPDLLKVCKEVDRN 220
Query: 243 PANVLINWGISRGYCVLPKSFTPARIASNKTPVHLSREDTERITKLSETLGVKRYVHPD- 301
P VLI W + GY LPK+ T R+ N + D + +K HPD
Sbjct: 221 PGQVLIRWSLQHGYLPLPKTKTVKRLEGNLAAYNFELSDEQ----------MKFLDHPDA 270
Query: 302 FEP 304
+EP
Sbjct: 271 YEP 273
>SPAP32A8.02 [R] KOG1577 Aldo/keto reductase family proteins
Length = 283
Score = 158 bits (399), Expect = 1e-38
Identities = 97/267 (36%), Positives = 143/267 (53%), Gaps = 33/267 (12%)
Query: 1 MTSPSGEFPSLKLNTGASIPQLGFGTWPSSHADAYTAVITALKTGYRHIDAAAMYGNEAA 60
M+ E ++ L G IP++GFG + + + Y V AL +GYRHID AA+YGNE
Sbjct: 1 MSESQTESTTVTLTNGMVIPRIGFGAFMLKYNECYGLVTQALDSGYRHIDTAAVYGNEDI 60
Query: 61 VGKGIRD----SGIPREEIFVTTKLWN-TQQRDPASALDESLERLGLDYVDLFLIHWPVP 115
GK I D + + R +IF+T+KL N + +A+ SL LG Y+DLFLI
Sbjct: 61 CGKAIVDWCEKNNVKRTDIFLTSKLANCSDYYSTRAAIRSSLHHLG-TYIDLFLIQ---- 115
Query: 116 LKPVGGPENLLKYPTPGIKPQIDTEDWSFIKTWELMQTLPKTGKTRAVGVSNFSIKNLED 175
P GG + S I +W+ M+ +G R+VGVSN+ +K+L++
Sbjct: 116 -SPAGGKK-------------------SRIASWKAMEEFVDSGDIRSVGVSNYGVKHLQE 155
Query: 176 LLNSSPDVLVPAVNQFEIHPQLPQTELINYCKSKGIVVEAYCPLGSSSSAMLSDPTIAEI 235
L S+P P VNQ E+HP L Q +++ YC+S I +EAY PL + L+D + I
Sbjct: 156 LYASNPK-FYPCVNQIELHPFLSQDDIVKYCQSHDIAIEAYSPL--THGIRLNDEKLVPI 212
Query: 236 ADKYHVKPANVLINWGISRGYCVLPKS 262
A K ++ A +LI W + +GY + KS
Sbjct: 213 AKKLNISVAQLLIRWSLQKGYIPIIKS 239
>CE01200 [R] KOG1577 Aldo/keto reductase family proteins
Length = 287
Score = 157 bits (396), Expect = 2e-38
Identities = 99/283 (34%), Positives = 154/283 (53%), Gaps = 29/283 (10%)
Query: 18 SIPQLGFGTWPSSHADAYTAVITA-LKTGYRHIDAAAMYGNEAAVGKGIRD----SGIPR 72
++P +G GTW + VI A K GYR ID A +Y NEA +G+ + +G+ R
Sbjct: 10 NMPLIGIGTWQVQKEEILRQVIDAGFKEGYRFIDTAQVYNNEAKIGRILEKLLPANGLKR 69
Query: 73 EEIFVTTKLW--NTQQRDPASALDESLERLGLDYVDLFLIHWPVPLKPVGGPENLLKYPT 130
E+I++T+KL N + +++ESL L ++Y+DL LIHWP + LK
Sbjct: 70 EDIWITSKLAPSNAGVKKARESIEESLSNLKVEYLDLLLIHWP---------GSSLKSEN 120
Query: 131 PGIKPQIDTEDWSFIKTWELMQTLPKTGKTRAVGVSNFSIKNLEDLLNSSPDVLVPAVNQ 190
P K +++W +M + GK R+VGVSNF I +LE+L S +VPAVNQ
Sbjct: 121 PANKKLR-------VESWNVMCEMMAEGKLRSVGVSNFEICHLEELKKDSN--VVPAVNQ 171
Query: 191 FEIHPQLPQTELINYCKSKGIVVEAYCPLGSSS--SAMLSDPTIAEIADKYHVKPANVLI 248
E HP Q +L+ YC I +AY LGS + + +P I E+A KY+V+ +L+
Sbjct: 172 VEYHPHFHQDDLVKYCNENNIHFQAYSSLGSPTYRKQLSEEPLIKELAQKYNVEIPVLLL 231
Query: 249 NWGISRGYCVLPKSFTPARIASN--KTPVHLSREDTERITKLS 289
+ +G VLP++ P +A+N T + +++ED +R+ L+
Sbjct: 232 GFAYCQGISVLPRTTNPEHVATNFKVTKLAITQEDIDRLLALT 274
>CE17230 [R] KOG1577 Aldo/keto reductase family proteins
Length = 333
Score = 155 bits (393), Expect = 5e-38
Identities = 109/318 (34%), Positives = 153/318 (47%), Gaps = 26/318 (8%)
Query: 10 SLKLNTGASIPQLGFGTWP-SSHADAYTAVITALKTGYRHIDAAAMYGNEAAVGKGIRD- 67
S+ LNTGA +P G GTW A+ A+ AL GYR ID A +Y NE +GK + +
Sbjct: 5 SIPLNTGAQLPLFGLGTWQVKDEAELTVALRAALDAGYRLIDTAHLYQNEHIIGKVLHEY 64
Query: 68 --SG-IPREEIFVTTKLWNTQQ--RDPASALDESLERLGLDYVDLFLIHWPVPLKPVGGP 122
SG + RE+IFVT+KL T D ++ L+ L L+Y+DL+LIH P P K G
Sbjct: 65 ISSGKLKREDIFVTSKLPFTAHAPEDVPKCVESQLKALQLEYIDLYLIHCPFPFKHQEGS 124
Query: 123 ENLLKYPTPGIKPQIDTEDWSFIKTWELMQTLPKTGKTRAVGVSNFSIKNLEDLLNSSPD 182
L ++ + + I TW ++ L K GK +A+GVSNFS L+ L +++
Sbjct: 125 FAPLME-----NGELAVTEIAHIDTWRALEKLYKEGKLKALGVSNFSCNQLQALYDAAE- 178
Query: 183 VLVPAVNQFEIHPQLPQTELINYCKSKGIVVEAYCPLGSSSSAM------------LSDP 230
+ PA Q E H PQ EL CK G+ V AY PLGS L +P
Sbjct: 179 -VKPANQQVECHIYWPQQELRALCKKLGVTVTAYAPLGSPGRKAARPDGVWPEGDPLLEP 237
Query: 231 TIAEIADKYHVKPANVLINWGISRGYCVLPKSFTPARIASNKTPVHLSREDTERITKLSE 290
+ ++A KYH A +LI G +PKS +P RI N + D + T S
Sbjct: 238 IVKQLAAKYHKTAAQILIRHLTQHGISTIPKSVSPDRIVENISTFDFKLSDEDMHTLNSI 297
Query: 291 TLGVKRYVHPDFEPYPLF 308
+ ++ +P F
Sbjct: 298 ETRTRLFIADFAVKHPFF 315
>Hs17450865 [R] KOG1577 Aldo/keto reductase family proteins
Length = 310
Score = 153 bits (387), Expect = 3e-37
Identities = 115/316 (36%), Positives = 151/316 (47%), Gaps = 41/316 (12%)
Query: 10 SLKLNTGASIPQLGFGTWPSSH---ADAYTAVITALKTGYRHIDAAAMYGNEAAVGKGI- 65
S++LN G +P LGFGT+ H + A A A+ G+RHID+A +Y NE VG+ I
Sbjct: 9 SVRLNDGPFMPVLGFGTYAPDHTPKSQAAEATKVAIDVGFRHIDSAYLYQNEEEVGQAIW 68
Query: 66 ---RDSGIPREEIFVTTKLWNTQQRDPA--SALDESLERLGLDYVDLFLIHWPVPLKPVG 120
D + REEIF T KLW T R AL+ SL++LG DYVDLF+IH P +KP
Sbjct: 69 EKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPFAMKP-- 126
Query: 121 GPENLLKYPTPGIKPQIDTEDWSFIKTWELMQTLPKTGKTRAVGVSNFSIKNLEDLLNSS 180
G E L K D ++T EL T G K LE +LN
Sbjct: 127 GKELLPK----------DASGEIILETVELCDTWENQGDKH---------KLLELILNKP 167
Query: 181 PDVLVPAVNQFEIHPQLPQTELINYCKSKGIVVEAYCPLGSSSSA---------MLSDPT 231
P NQ E HP L Q++L+ +CKSK IV+ AY LGS +L +P
Sbjct: 168 GLRYKPTCNQVECHPYLNQSKLLEFCKSKDIVLVAYSALGSQRDPQWVDPDCPHLLEEPI 227
Query: 232 IAEIADKYHVKPANVLINWGISRGYCVLPKSFTPARIASNKT--PVHLSREDTERITKLS 289
+ IA K+ P V + + + RG VL KSF+ RI N L+ ED + I L+
Sbjct: 228 LKSIAKKHSRSPGQVALRYQLQRGVVVLAKSFSQERIKENFQIFDFELTPEDMKAIDGLN 287
Query: 290 ETLGVKRYVHPDFEPY 305
L + PY
Sbjct: 288 RNLRYDKLQFAANHPY 303
>Hs5174695 [R] KOG1577 Aldo/keto reductase family proteins
Length = 326
Score = 152 bits (385), Expect = 5e-37
Identities = 108/326 (33%), Positives = 160/326 (48%), Gaps = 38/326 (11%)
Query: 11 LKLNTGASIPQLGFGTWPSSHAD----AYTAVITALKTGYRHIDAAAMYGNEAAVGKGIR 66
+ L+ G SIP +G GT+ + T+V A+ TGYRHID A +Y NE VG+ IR
Sbjct: 10 IPLSDGNSIPIIGLGTYSEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEVGEAIR 69
Query: 67 DS----GIPREEIFVTTKLWNTQQRDPA--SALDESLERLGLDYVDLFLIHWPVPLKPVG 120
+ + RE+IF KLW T L+ +L L LDYVDL++I P+ KP
Sbjct: 70 EKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFKP-- 127
Query: 121 GPENLLKYPTPGIKPQIDTEDWSFIK-----TWELMQTLPKTGKTRAVGVSNFSIKNLED 175
G E I P+ + W + K TWE M+ G +++GVSNF+ + LE
Sbjct: 128 GDE---------IYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLEL 178
Query: 176 LLNSSPDVLVPAVNQFEIHPQLPQTELINYCKSKGIVVEAYCPLGS---------SSSAM 226
+LN P NQ E HP Q +L+ +C+ IV+ AY PLG+ SS +
Sbjct: 179 ILNKPGLKHKPVSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLGTSRNPIWVNVSSPPL 238
Query: 227 LSDPTIAEIADKYHVKPANVLINWGISRGYCVLPKSFTPARIASNKT--PVHLSREDTER 284
L D + + +Y+ A +++ + I RG V+PKSF RI N L+ E+ +
Sbjct: 239 LKDALLNSLGKRYNKTAAQIVLRFNIQRGVVVIPKSFNLERIKENFQIFDFSLTEEEMKD 298
Query: 285 ITKLSETLG-VKRYVHPDFEPYPLFE 309
I L++ + V+ + D YP +
Sbjct: 299 IEALNKNVRFVELLMWRDHPEYPFHD 324
>CE06776 [R] KOG1577 Aldo/keto reductase family proteins
Length = 317
Score = 152 bits (385), Expect = 5e-37
Identities = 106/318 (33%), Positives = 156/318 (48%), Gaps = 46/318 (14%)
Query: 10 SLKLNTGASIPQLGFGTWPSSHADAYTAVITALKTGYRHIDAAAMYGNEAAVGKGIR--- 66
S+KL+ G +P +G GTW SS A+ TAV TA+K GYR ID A++Y NE A+G I+
Sbjct: 7 SIKLSNGVEMPVIGLGTWQSSPAEVITAVKTAVKAGYRLIDTASVYQNEEAIGTAIKELL 66
Query: 67 -DSGIPREEIFVTTKLWNTQQRDPA---SALDESLERLGLDYVDLFLIHWPVPLKPVGGP 122
+ + REE+F+TTK W T + P L ESL++L L+YVDL+L H P
Sbjct: 67 EEGVVKREELFITTKAW-THELAPGKLEGGLRESLKKLQLEYVDLYLAHMPAAFN----- 120
Query: 123 ENLLKYPTPGIKPQIDTEDWSFIKTWELMQTLPKTGKTRAVGVSNFSIKNLEDLLNSSPD 182
+++ ++ ++ W + K G +AVGVSN+ N + + +
Sbjct: 121 DDMSEHIASPVE-----------DVWRQFDAVYKAGLAKAVGVSNW---NNDQISRALAL 166
Query: 183 VLVPAVN-QFEIHPQLPQTELINYCKSKGIVVEAYCPLGS-----------------SSS 224
L P N Q E+H PQ + +++CK I V +Y LGS +
Sbjct: 167 GLTPVHNSQVELHLYFPQHDHVDFCKKHNISVTSYATLGSPGRVNFTLPTGQKLDWAPAP 226
Query: 225 AMLSDPTIAEIADKYHVKPANVLINWGISRGYCVLPKSFTPARIASNKTPVHLSREDTER 284
+ L D + +A+K H PA VL+ + + RG +LPKS RI N S + E
Sbjct: 227 SDLQDQNVLALAEKTHKTPAQVLLRYALDRGCAILPKSIQENRIKENFEVFDFSLTE-ED 285
Query: 285 ITKLSETLGVKRYVHPDF 302
I KL E+ +R DF
Sbjct: 286 IAKLEESKNSQRLFLQDF 303
>7294572 [R] KOG1577 Aldo/keto reductase family proteins
Length = 317
Score = 151 bits (382), Expect = 1e-36
Identities = 98/275 (35%), Positives = 136/275 (48%), Gaps = 19/275 (6%)
Query: 9 PSLKLNTGASIPQLGFGTWPSSHADAYTAVITALKTGYRHIDAAAMYGNEAAVGKGIRD- 67
P++KLN G +P LG GT+ S + AV A+ GYRHID A Y NEA VGK IRD
Sbjct: 5 PTVKLNNGYEMPILGLGTYNSKDNEGEAAVKHAIDVGYRHIDTAYFYQNEAEVGKAIRDK 64
Query: 68 ---SGIPREEIFVTTKLWNTQQRDP---ASALDESLERLGLDYVDLFLIHWPVPLKPVGG 121
+ RE+IF+ TKLWN DP + L GLDY+DL+L+H PV K V
Sbjct: 65 IAEGVVKREDIFLVTKLWNI-FHDPERVEGICRKQLSNFGLDYIDLYLMHMPVGYKYVDD 123
Query: 122 PENLLKYPTPGIKPQIDTEDWSFIKTWELMQTLPKTGKTRAVGVSNFSIKNLEDLLNSSP 181
L K + D ++ T++ M+ L K G R++GVSNF+ + L +L +
Sbjct: 124 NTLLPK----NEDDVLQLSDVDYLDTYKAMEKLVKLGLVRSIGVSNFNSEQLARVLANCE 179
Query: 182 DVLVPAVNQFEIHPQLPQTELINYCKSKGIVVEAYCPLGS-----SSSAMLSDPTIAEIA 236
+ P NQ E P L Q L +CK + + Y PLG + P +A IA
Sbjct: 180 --IKPVTNQVECSPALNQKALTAFCKKNDVTLTGYTPLGKPKPDIQKPDFIYSPEVAVIA 237
Query: 237 DKYHVKPANVLINWGISRGYCVLPKSFTPARIASN 271
KY +++ + + G +PKS RI+ N
Sbjct: 238 KKYGKTTPQIVLRYLVGLGVIPIPKSSNTNRISEN 272
>Hs17465400 [R] KOG1577 Aldo/keto reductase family proteins
Length = 384
Score = 149 bits (376), Expect = 5e-36
Identities = 115/356 (32%), Positives = 155/356 (43%), Gaps = 78/356 (21%)
Query: 11 LKLNTGASIPQLGFGTWPSSHADAYTAVITALKTGYRHIDAAAMYGNEAAVGKGIRDS-- 68
++L+T A +P +G GTW S AV A+ YRHID A Y N+ VG+ I++
Sbjct: 5 VELSTKAKMPIVGLGTWRSLLGKVKEAVKVAIDAEYRHIDCAYFYENQHEVGEAIQEKIQ 64
Query: 69 --GIPREEIFVTTKL------WNTQQRDPA--SALDESLERLGLDYVDLFLIHWPVPLKP 118
+ RE++F+ +K+ W T P A +++L+ L L Y+D++LIHWP K
Sbjct: 65 EKAVMREDLFIVSKVHMAHLVWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKS 124
Query: 119 VG------------GPENLLK-----------------------YPTPGIKPQIDTEDWS 143
+ PE LL +P K + + +
Sbjct: 125 LKKWYADVVFSKHQDPETLLNRTKCPDADSSKLFILYLQTGDDFFPKDD-KGNMISGKGT 183
Query: 144 FIKTWELMQTLPKTGKTRAVGVSNFSIKNLEDLLNSSPDVLVPAVNQ------------- 190
F+ WE M+ L G +A+GVSNF+ +E LLN P NQ
Sbjct: 184 FLDAWEAMEELVDEGLVKALGVSNFNHFQIERLLNKPGLKYKPVTNQNSLGTMQNRAGFP 243
Query: 191 ---------FEIHPQLPQTELINYCKSKGIVVEAYCPLGS--------SSSAMLSDPTIA 233
E HP L Q +LI YC SKGI V AY PLGS ++L DP I
Sbjct: 244 RDEDCLLLQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIK 303
Query: 234 EIADKYHVKPANVLINWGISRGYCVLPKSFTPARIASNKTPVHLSREDTERITKLS 289
EIA K+ A VLI + I R V+PKS TPA I N D E T LS
Sbjct: 304 EIAAKHKKTTAQVLIRFHIQRNVTVIPKSMTPAHIVENIQVFDFKLSDEEMATILS 359
>CE10934 [R] KOG1577 Aldo/keto reductase family proteins
Length = 297
Score = 149 bits (375), Expect = 7e-36
Identities = 89/289 (30%), Positives = 147/289 (50%), Gaps = 28/289 (9%)
Query: 10 SLKLNTGASIPQLGFGTWPSSHADAYTAVITALKTGYRHIDAAAMYGNEAAVGKGIR--- 66
S KLN+G +IP +GFGT+ + + A+ AL GYR D A Y NE +G+ ++
Sbjct: 12 SQKLNSGYNIPFVGFGTYKVTGENVPPAIDAALTAGYRMFDTAKYYLNEKELGEALKILL 71
Query: 67 -DSGIPREEIFVTTKLWNTQQRDPASA---LDESLERLGLDYVDLFLIHWPVPLKPVGGP 122
G+ R ++F+T+K + + + ++ESL+ L DY+D++L+H
Sbjct: 72 PKHGLSRSDVFLTSKFFPESKNCREACRGFVEESLQSLQTDYIDMYLVH----------- 120
Query: 123 ENLLKYPTPGIKPQIDTEDWSFIK-TWELMQTLPKTGKTRAVGVSNFSIKNLEDLLNSSP 181
YP P D + + K +E+++ GK R++GVSN+ I +LE+L +
Sbjct: 121 -----YPKPNDSDNDDVNNAEYRKIAYEVLEEAKAAGKVRSIGVSNYEIVHLEELKTYAK 175
Query: 182 DVLVPAVNQFEIHPQLPQTELINYCKSKGIVVEAYCPLGSSSSAMLSDPTIAEIADKYHV 241
+ P NQ E HP + L YCK K I +A+ L ++ DP + E+A K++
Sbjct: 176 --VPPCANQLEYHPHFARIPLQKYCKEKNIFFQAFSSLARHEPKLIEDPVVVELAKKHNT 233
Query: 242 KPANVLINWGISRGYCVLPKSFTPARIASN--KTPVHLSREDTERITKL 288
VL+ W + + ++PKS TP+RI N + L+ ED + +T L
Sbjct: 234 SVPLVLLAWALRQNVGIVPKSVTPSRIVENFKVIDIALTPEDIQSLTAL 282
>CE24244 [R] KOG1577 Aldo/keto reductase family proteins
Length = 339
Score = 145 bits (366), Expect = 7e-35
Identities = 98/319 (30%), Positives = 159/319 (49%), Gaps = 26/319 (8%)
Query: 10 SLKLNTGASIPQLGFGTWPSSHADAYTAVITALKTGYRHIDAAAMYGNEAAVGKGIRD-- 67
++ LN+G +P +G+GTW A V AL+ GYRHID+A + N+ V GI+D
Sbjct: 6 TVTLNSGYEMPVIGYGTWQLPKNLAAERVRDALEAGYRHIDSALSFKNQEEVAAGIKDWC 65
Query: 68 --SGIPREEIFVTTKLWNT--QQRDPASALDESLERLGLDYVDLFLIHWPVPLKPVGGPE 123
+ REE+F+++K+WNT + +DE LE Y+DL +IHWP P
Sbjct: 66 KIRKVRREELFLSSKIWNTYHSRNRCMQQIDEMLEIFETTYMDLIVIHWPFGWAEDEPPG 125
Query: 124 NLLKYPTPGIKPQIDTEDWSFIKTWELMQTLPKTGKTRAVGVSNFSIKNLEDLLNSSPDV 183
+P G ++ D +++TW+ ++ ++GK R++G++NF+I +E + +
Sbjct: 126 ERGLWPR-GANGKMRYSDVDYLETWKALEDAHRSGKIRSIGLANFNIGQVEQVWTKG--L 182
Query: 184 LVPAVNQFEIHPQLPQTELINYCKSKGIVVEAYCPLGSSSSA---------MLSDPTIAE 234
+ PAV Q E++P L Q E+ +C+ KGI++ A+ G+ SA +L + T+
Sbjct: 183 IKPAVLQVEMNPFLDQEEIRQFCREKGIILTAFMLTGNPGSALYRKHEDPNLLYNETLQS 242
Query: 235 IADKYHVKPANVLINWGISRGYCVLPKSFTPARIASNKT--PVHLSREDTERITKLSETL 292
IA + VL+ W I L KS RI N L+ ++ RI L+
Sbjct: 243 IAKGHGKSVVQVLVRWAIDLRTTALVKSSESKRIRQNINIFKFRLTSQEIARIKALNIDF 302
Query: 293 GV-----KRYVHPDFEPYP 306
+ Y HP F P+P
Sbjct: 303 RILNPLLGNYDHPYF-PWP 320
>7294573 [R] KOG1577 Aldo/keto reductase family proteins
Length = 252
Score = 145 bits (366), Expect = 7e-35
Identities = 91/253 (35%), Positives = 136/253 (52%), Gaps = 18/253 (7%)
Query: 9 PSLKLNTGASIPQLGFGTWPSSHADAYTAVITALKTGYRHIDAAAMYGNEAAVGKG---- 64
P++KLN G +P LG GT+ + AV AL+ GYRHID A +Y NE +GK
Sbjct: 5 PTVKLNNGYEMPILGLGTYNLKKSRCEAAVCHALEMGYRHIDTAYLYRNEGIIGKVLAKL 64
Query: 65 IRDSGIPREEIFVTTKLWNT--QQRDPASALDESLERLGLDYVDLFLIHWPVPLKPVGGP 122
I D + RE++F+ TKLW+ + + A D L+ LG+DY+DL+L+H PV + +
Sbjct: 65 IGDQKLKREQVFLVTKLWDIYHEPKMVKYACDMQLKLLGVDYIDLYLMHSPVGVDYI-SD 123
Query: 123 ENLLKYPTPGIKPQIDTEDWSFIKTWELMQTLPKTGKTRAVGVSNFSIKNLEDLLNSSPD 182
E+L+ P Q+ T D ++ T+ M+ L G R++G+SNF+ L+ LL +
Sbjct: 124 EDLM----PHENGQLRTNDVDYVDTYRSMEQLVHLGLVRSLGLSNFNANQLKRLLENCQ- 178
Query: 183 VLVPAVNQFEIHPQLPQTELINYCKSKGIVVEAYCPLGSSSSA-----MLSDPTIAEIAD 237
+ PA Q E HP+L Q LI CK I V AY PLG + +D + +A
Sbjct: 179 -IKPANLQIECHPELVQVPLIELCKFHNITVVAYSPLGRPKACNPLPDYYTDSKLLALAA 237
Query: 238 KYHVKPANVLINW 250
KY PA +++ +
Sbjct: 238 KYGKTPAQIILRY 250
>CE06751 [R] KOG1577 Aldo/keto reductase family proteins
Length = 287
Score = 145 bits (365), Expect = 9e-35
Identities = 94/281 (33%), Positives = 140/281 (49%), Gaps = 27/281 (9%)
Query: 12 KLNTGASIPQLGFGTWPSSHADAYTAVITALKTGYRHIDAAAMYGNEAAVGKGIRDSGIP 71
KL G IP+L GT+ + + AV ALK GYR D A Y NE +G ++ +P
Sbjct: 3 KLKNGQEIPKLALGTYEAKGDQLFAAVDEALKVGYRSFDTAKYYENEKDLGLALKTL-LP 61
Query: 72 R-----EEIFVTTKLWNTQQRDPASAL----DESLERLGLDYVDLFLIHWPVPLKPVGGP 122
R E+I++T+K++ ++ A + +ESLE L Y+DL L+H+P PL
Sbjct: 62 RHNICSEDIYLTSKVFPYSSKNAAELIRKDVNESLELLDRKYLDLVLVHYPRPLDTEDLN 121
Query: 123 ENLLKYPTPGIKPQIDTEDWSFIKTWELMQTLPKTGKTRAVGVSNFSIKNLEDLLNSSPD 182
EN Y TW ++ L GK R++GVSN+ ++E++ S
Sbjct: 122 ENNKMYRKD---------------TWIALEKLHAEGKIRSIGVSNYEPHHIEEM--RSYI 164
Query: 183 VLVPAVNQFEIHPQLPQTELINYCKSKGIVVEAYCPLGSSSSAMLSDPTIAEIADKYHVK 242
+ P VNQ E HP + L YC I+ +A+ PLG + +L D T+ IA +
Sbjct: 165 TIEPQVNQIEYHPHFQRKVLRAYCNKNEILFQAFSPLGRGNKTLLGDSTMERIALCHKTT 224
Query: 243 PANVLINWGISRGYCVLPKSFTPARIASNKTPVHLSREDTE 283
ANV++ W + Y V+ KS TP+R+A N T + L D E
Sbjct: 225 VANVILAWIMKGKYGVVAKSVTPSRVAENYTSLSLELSDDE 265
>At1g59960 [R] KOG1577 Aldo/keto reductase family proteins
Length = 326
Score = 142 bits (359), Expect = 5e-34
Identities = 103/302 (34%), Positives = 151/302 (49%), Gaps = 38/302 (12%)
Query: 9 PSLKLNTGAS----IPQLGFGTWPSSHADAYT---AVITALKTGYRHIDAAAMYGNEAAV 61
P+L + +G S +P LGFGT S + VI A+K GYRH D + Y E +
Sbjct: 7 PTLAIRSGPSGHHSMPVLGFGTAASPLPEPTMLKETVIEAIKLGYRHFDTSPRYQTEEPI 66
Query: 62 GKGIRDS---GI--PREEIFVTTKLWNTQQRDP--ASALDESLERLGLDYVDLFLIHWPV 114
G+ + ++ G+ R E FVTTKLW A+ SL+ L LDY+DL++IHWPV
Sbjct: 67 GEALAEAVSLGLVRSRSEFFVTTKLWCADAHGGLVVPAIKRSLKNLKLDYLDLYIIHWPV 126
Query: 115 PLKPVGGPENLLKYPTPGIKPQIDTEDW---SFIKTWELMQTLPKTGKTRAVGVSNFSIK 171
KP KY P ID +D+ F W M+ + G + +GVSNFS K
Sbjct: 127 SSKPG-------KYKFP-----IDEDDFMPMDFEVVWSEMEECQRLGLAKCIGVSNFSCK 174
Query: 172 NLEDLLNSSPDVLVPAVNQFEIHPQLPQTELINYCKSKGIVVEAYCPLGS-----SSSAM 226
L+ +L+ + + P+VNQ E+ P Q +L C+S IVV AY LGS + +
Sbjct: 175 KLQHILSIA--TIPPSVNQVEMSPIWQQRKLRELCRSNDIVVTAYSVLGSRGAFWGTPKI 232
Query: 227 LSDPTIAEIADKYHVKPANVLINWGISRGYCVLPKSFTPARIASNKT--PVHLSREDTER 284
+ + EIA+ A V + W +G ++ KSFT R+ N L+ ++T+R
Sbjct: 233 MESDVLKEIAEAKEKTVAQVSMRWAYEQGVSMVVKSFTKERLEENLKIFDWSLTEDETQR 292
Query: 285 IT 286
I+
Sbjct: 293 IS 294
>SPAC19G12.09 [R] KOG1577 Aldo/keto reductase family proteins
Length = 284
Score = 141 bits (356), Expect = 1e-33
Identities = 86/234 (36%), Positives = 128/234 (53%), Gaps = 34/234 (14%)
Query: 37 AVITALKTGYRHIDAAAMYGNEAAVGKGIRDSGIPREEIFVTTKLWNTQQRDPASALDES 96
+V AL G+ HID A +YGNE VG ++++ +PR ++F+T+K+ + P AL+ES
Sbjct: 36 SVKNALAAGFIHIDCAEVYGNEEEVGVALKEANVPRSKLFITSKVMHNVDNIP-EALNES 94
Query: 97 LERLGLDYVDLFLIHWPVPLKPVGGPENLLKYPTPGIKPQIDTEDWSFIKTWELMQTLPK 156
L +LG DY+DL+L+H P+P P + W+ M+T
Sbjct: 95 LRKLGTDYLDLYLLHSPIPFYEKKIP---------------------ISEGWKAMETALG 133
Query: 157 TGKTRAVGVSNFSIKNLEDLLNSSPDVLVPAVNQFEIHPQLPQT--ELINYCKSKGIVVE 214
TG +VGVSNF I +LE+LL +S + P VNQ E HPQ+ + L+ +C+SKGI+VE
Sbjct: 134 TGLVHSVGVSNFRIPDLEELLKTS--TITPRVNQIEFHPQVYKAAKPLVEFCQSKGIIVE 191
Query: 215 AYCPLGSSSSAMLSDPTIAE----IADKYHVKPANVLINWGISRGYCVLPKSFT 264
Y PL S + +AE + KYHV +L+ W S+G V+P + T
Sbjct: 192 GYGPL--SPLVRDAQGPVAEFTKSLESKYHVSDTQILLKWAYSKG--VIPITTT 241
>Hs22054710 [R] KOG1577 Aldo/keto reductase family proteins
Length = 418
Score = 140 bits (353), Expect = 2e-33
Identities = 103/272 (37%), Positives = 140/272 (50%), Gaps = 46/272 (16%)
Query: 10 SLKLNTGASIPQLGFGTWPSSH---ADAYTAVITALKTGYRHIDAAAMYGNEAAVGKGIR 66
S++LN G +P LGFGT+ H + A A A+ G+RHIDAA Y NE VGK IR
Sbjct: 8 SVRLNDGHVMPMLGFGTYAPDHTPKSKAGEATEVAIDAGFRHIDAAFFYQNEEEVGKAIR 67
Query: 67 ----DSGIPREEIFVTTKLWNTQQRDPA--SALDESLERLGLDYVDLFLIHWPVPLKPVG 120
D + RE+IF TT+LW T R AL+ SL++L LDYVDLF+IH P+ +K +
Sbjct: 68 EKIADGPVKREDIFYTTELWTTFFRPELVRPALEGSLKKLQLDYVDLFIIHNPLAMKLLR 127
Query: 121 G--------PENLLKYPTPG--IKPQ-------IDTEDWSFIKTWELMQTLPKTGKTRAV 163
P +L PG + P+ DT D TWE ++ + G T+++
Sbjct: 128 RQKGNSHRKPSSLSSVFQPGEELLPKDASGNIIFDTVDLR--DTWEALEKCKEAGLTKSI 185
Query: 164 GVSNFSIKNLEDLLNSSPDVLVPAVNQFEIHPQLPQTELINYCKSKGIVVEAYCPLGS-- 221
GVSNF+ K LE +LN P N Q++L+ +CKSK IV+ AY L S
Sbjct: 186 GVSNFNHKLLELILNKPGLKYKPTCN---------QSKLLEFCKSKDIVLVAYRALASHR 236
Query: 222 -------SSSAMLSDPTIAEIADKYHVKPANV 246
S +L +PT+ IA KY+ P V
Sbjct: 237 DPNWMDPDSPYLLEEPTLKSIAKKYNRSPGQV 268
>At1g59950 [R] KOG1577 Aldo/keto reductase family proteins
Length = 320
Score = 135 bits (340), Expect = 7e-32
Identities = 99/294 (33%), Positives = 147/294 (49%), Gaps = 35/294 (11%)
Query: 19 IPQLGFGTWPSSHADAYT---AVITALKTGYRHIDAAAMYGNEAAVGKGIRDS---GI-- 70
+P L GT S + V+ A+K GYRH D + Y E +G+ + ++ G+
Sbjct: 15 MPVLALGTAASPPPEPIVLKRTVLEAIKLGYRHFDTSPRYQTEEPLGEALAEAVSLGLIQ 74
Query: 71 PREEIFVTTKLWNTQQRDP--ASALDESLERLGLDYVDLFLIHWPVPLKPVGGPENLLKY 128
R E+FVT+KLW A+ SLE L LDY+DL+LIHWPV KP KY
Sbjct: 75 SRSELFVTSKLWCADAHGGLVVPAIQRSLETLKLDYLDLYLIHWPVSSKPG-------KY 127
Query: 129 PTPGIKPQIDTEDW---SFIKTWELMQTLPKTGKTRAVGVSNFSIKNLEDLLNSSPDVLV 185
P I+ +D+ + W M+ + G + +GVSNFS K L+ +L+ + +
Sbjct: 128 KFP-----IEEDDFLPMDYETVWSEMEECQRLGVAKCIGVSNFSCKKLQHILSIAK--IP 180
Query: 186 PAVNQFEIHPQLPQTELINYCKSKGIVVEAYCPLGS-----SSSAMLSDPTIAEIADKYH 240
P+VNQ E+ P Q +L CKSKGIVV AY LGS + ++ + EIA+
Sbjct: 181 PSVNQVEMSPVWQQRKLRELCKSKGIVVTAYSVLGSRGAFWGTHKIMESDVLKEIAEAKG 240
Query: 241 VKPANVLINWGISRGYCVLPKSFTPARIASNKT--PVHLSREDTERI-TKLSET 291
A V + W G ++ KSF R+ N L+ E+ +RI T++S++
Sbjct: 241 KTVAQVSMRWAYEEGVSMVVKSFRKDRLEENLKIFDWSLTEEEKQRISTEISQS 294
>YHR104w [R] KOG1577 Aldo/keto reductase family proteins
Length = 327
Score = 132 bits (331), Expect = 8e-31
Identities = 92/286 (32%), Positives = 130/286 (45%), Gaps = 33/286 (11%)
Query: 13 LNTGASIPQLGFGTWPSSHADAYTAVITALKTGYRHIDAAAMYGNEAAVGKGIR----DS 68
LN G +P +G G W + A+K GYR D A YGNE VG+GIR +
Sbjct: 7 LNNGLKMPLVGLGCWKIDKKVCANQIYEAIKLGYRLFDGACDYGNEKEVGEGIRKAISEG 66
Query: 69 GIPREEIFVTTKLWNTQQRDP--ASALDESLERLGLDYVDLFLIHWPVPLKPVGGPENLL 126
+ R++IFV +KLWN AL ++L +GLDY+DL+ IH+P+ K V E
Sbjct: 67 LVSRKDIFVVSKLWNNFHHPDHVKLALKKTLSDMGLDYLDLYYIHFPIAFKYVPFEE--- 123
Query: 127 KYPTPGIKPQIDTEDWS--------FIKTWELMQTLPKTGKTRAVGVSNFSIKNLEDLLN 178
KYP PG D E I T+ ++ G +++GVSNF ++DLL
Sbjct: 124 KYP-PGFYTGADDEKKGHITEAHVPIIDTYRALEECVDEGLIKSIGVSNFQGSLIQDLLR 182
Query: 179 SSPDVLVPAVNQFEIHPQLPQTELINYCKSKGIVVEAYCPLGSSS------------SAM 226
+ P Q E HP L Q L+ +CK I V AY G S +
Sbjct: 183 GCR--IKPVALQIEHHPYLTQEHLVEFCKLHDIQVVAYSSFGPQSFIEMDLQLAKTTPTL 240
Query: 227 LSDPTIAEIADKY-HVKPANVLINWGISRGYCVLPKSFTPARIASN 271
+ I +++ + + VL+ W RG V+PKS R+ N
Sbjct: 241 FENDVIKKVSQNHPGSTTSQVLLRWATQRGIAVIPKSSKKERLLGN 286
>CE27788 [R] KOG1577 Aldo/keto reductase family proteins
Length = 320
Score = 130 bits (327), Expect = 2e-30
Identities = 91/293 (31%), Positives = 134/293 (45%), Gaps = 45/293 (15%)
Query: 5 SGEFPSLKLNTGASIPQLGFGTWPSSHADAYTAVITALKTGYRHIDAAAMYGNEAAVGKG 64
S + P L+ G +P +G GTW + + T + A+ GYRHID A +Y NE +G
Sbjct: 2 SSKVPIFTLSNGVLMPSIGLGTWQMTGEEGKTVIRNAVLAGYRHIDTATLYQNEHQIGDA 61
Query: 65 IRD---SGI-PREEIFVTTKLWNTQQRDPA--SALDESLERLGLDYVDLFLIHWPVPLKP 118
+ + GI RE+IF+TTK + + AL SL+RL LDYVDL+L H P K
Sbjct: 62 LAELFAEGILKREDIFITTKAFCHEVAPDVVEEALRNSLKRLRLDYVDLYLAHIPASTKD 121
Query: 119 VGGPENLLKYPTPGIKPQIDTEDWSFIKTWELMQTLPKTGKTRAVGVSNFSIKNLEDLLN 178
G + + ED W + + G T+A+GVSNF+ + ++N
Sbjct: 122 DG-----------SFRSDVKVED-----IWRGFEKVYGLGLTKAIGVSNFNESQIVRIMN 165
Query: 179 SSPDVLVPA-VNQFEIHPQLPQTELINYCKSKGIVVEAYCPLGS---------------- 221
VP +Q E+H LPQ CK I++ AY LGS
Sbjct: 166 IQK---VPIHASQLELHLYLPQKAHRELCKKHNILITAYATLGSPGRMSVVGSNGRPLFE 222
Query: 222 ---SSSAMLSDPTIAEIADKYHVKPANVLINWGISRGYCVLPKSFTPARIASN 271
+S ++D + +A KY PA +L+ + G V+PK+ P R+ N
Sbjct: 223 STQNSENEMNDKHVKALAQKYSKTPAQILLRATVEMGIIVIPKTTNPERMKEN 275
>Hs20545142 [R] KOG1577 Aldo/keto reductase family proteins
Length = 280
Score = 127 bits (320), Expect = 2e-29
Identities = 92/271 (33%), Positives = 125/271 (45%), Gaps = 56/271 (20%)
Query: 11 LKLNTGASIPQLGFGTWPSSHADAYTAVITALKTGYRHIDAAAMYGNEA--AVGKGIRDS 68
L LN G +P LG GTW S AV A+ GY HID A + NE A+ + +R+
Sbjct: 5 LVLNNGTKMPILGLGTWKSPPGRVTEAVNVAINVGYCHIDCAH-HENEVGVAIQEKLREQ 63
Query: 69 GIPREEIFVTTKLWNTQQRDPASALDESLERLGLDYVDLFLIHWPVPLKPVGGPENLLKY 128
+ REE+F+ T + +F PL +G
Sbjct: 64 VVKREELFIVT------------------------WEGIF------PLNELGN------- 86
Query: 129 PTPGIKPQIDTEDWSFIKTWELMQTLPKTGKTRAVGVSNFSIKNLEDLLNSSPDVLVPAV 188
+ D + + TW M+ L +A+G+SNF+ +E LLN P V
Sbjct: 87 --------VVPSDTNILDTWAAMEELVDEWLMKAIGISNFNHLQVERLLNKPGLKYKPVV 138
Query: 189 NQFEIHPQLPQTELINYCKSKGIVVEAYCPLGSSS--------SAMLSDPTIAEIADKYH 240
NQ E HP L Q +LI YC+SKGIVV AY P+G+ S ++L DP I IA K++
Sbjct: 139 NQIECHPYLTQEKLIQYCQSKGIVVTAYSPVGTPSRPWVNPEDPSLLRDPRIKAIAAKHN 198
Query: 241 VKPANVLINWGISRGYCVLPKSFTPARIASN 271
A VLI + + R V+PKS TP IA N
Sbjct: 199 KTTAQVLIRFPMQRNLGVIPKSVTPELIADN 229
>YDL124w [R] KOG1577 Aldo/keto reductase family proteins
Length = 312
Score = 123 bits (308), Expect = 4e-28
Identities = 96/301 (31%), Positives = 147/301 (47%), Gaps = 48/301 (15%)
Query: 13 LNTGASIPQL---GFGT--WPSSHADAYTA------VITALKT-GYRHIDAAAMYGNEAA 60
LN G IP + G GT + + DA + ++ ALK G HIDAA +Y
Sbjct: 10 LNNGNKIPAIAIIGTGTRWYKNEETDATFSNSLVEQIVYALKLPGIIHIDAAEIYRTYPE 69
Query: 61 VGKGIRDSGIPREEIFVTTKLWNTQQR---DPASALDESLERLGLDYVDLFLIHWPVPLK 117
VGK + + PR IF+T K ++ Q + PA LD +L+++G DYVDL+L+H P K
Sbjct: 70 VGKALSLTEKPRNAIFLTDK-YSPQIKMSDSPADGLDLALKKMGTDYVDLYLLHSPFVSK 128
Query: 118 PVGGPENLLKYPTPGIKPQIDTEDWSFIKTWELMQTLPKTGKTRAVGVSNFSIKNLEDLL 177
V G S + W+ M+ L K+GK + +GVSNF++++L+ +L
Sbjct: 129 EVNG--------------------LSLEEAWKDMEQLYKSGKAKNIGVSNFAVEDLQRIL 168
Query: 178 NSSPDVLVPAVNQFEIHPQLPQTE--LINYCKSKGIVVEAYCPLGSSSSAMLSDPT---- 231
+ + P VNQ E P L + +C+ I+VEAY PLG D +
Sbjct: 169 KVAE--VKPQVNQIEFSPFLQNQTPGIYKFCQEHDILVEAYSPLGPLQKKTAQDDSQPFF 226
Query: 232 --IAEIADKYHVKPANVLINWGISRGYCVLPKSFTPARI--ASNKTPVHLSREDTERITK 287
+ E+++KY A +++ W RG + S P RI A N L+ E+ ++IT+
Sbjct: 227 EYVKELSEKYIKSEAQIILRWVTKRGVLPVTTSSKPQRISDAQNLFSFDLTAEEVDKITE 286
Query: 288 L 288
L
Sbjct: 287 L 287
>Hs20470761 [R] KOG1577 Aldo/keto reductase family proteins
Length = 222
Score = 122 bits (306), Expect = 7e-28
Identities = 87/245 (35%), Positives = 112/245 (45%), Gaps = 43/245 (17%)
Query: 11 LKLNTGASIPQLGFGTWPSSHADAYTAVITALKTGYRHIDAAAMYGNEAAVGKGIRDS-- 68
++LNT A +P +G GTW S V A+ GYRHID A +Y NE VG+ I++
Sbjct: 5 VELNTKAKMPIVGLGTWKSPLGKVKEVVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQ 64
Query: 69 --GIPREEIFVTTKLWNTQQRDPASALDESLERLGLDYVDLFLIHWPVPLKPVGGPENLL 126
+ RE++F+ KLW T P LG D F +GG
Sbjct: 65 EKAVKREDLFIINKLWPTFFERP----------LGYKSGDDFF-RKDDKGNMIGGKA--- 110
Query: 127 KYPTPGIKPQIDTEDWSFIKTWELMQTLPKTGKTRAVGVSNFSIKNLEDLLNSSPDVLVP 186
F+ WE M+ L G +A+GVSNF+ +E LLN P
Sbjct: 111 ----------------MFLDAWEAMEELVDEGLVKALGVSNFNHFQIERLLNKPGLKYKP 154
Query: 187 AVNQFEIHPQLPQTELINYCKSKGIVVEAYCPLGS--------SSSAMLSDPTIAEIADK 238
NQ E HP L Q +LI YC SKGI + AY PLGS ++L DP I EIA +
Sbjct: 155 VTNQVECHPYLTQEKLIQYCHSKGITIMAYSPLGSPDRLWAKPEDPSLLEDPKIKEIAAR 214
Query: 239 YHVKP 243
H KP
Sbjct: 215 -HKKP 218
>CE15543 [R] KOG1577 Aldo/keto reductase family proteins
Length = 376
Score = 118 bits (296), Expect = 9e-27
Identities = 97/342 (28%), Positives = 149/342 (43%), Gaps = 86/342 (25%)
Query: 9 PSLKLNTGASIPQLGFGTWPSSHADAY--TAVITALKT-GYRHIDAAAMYGNEAAVGKGI 65
P+ L+ +P +G GT +H+ Y AV+ ++K GYR ID A YG E +G +
Sbjct: 3 PTTVLSNNVEMPLIGLGT---THSGGYYHDAVLHSIKKCGYRLIDTAKRYGVEKQLGIAV 59
Query: 66 RDSGIPREEIFVTTKLWNTQQRDPA-SALDESLERLGLDYVDLFLIHWPVPLKPVGGPEN 124
++ +PREE+F++TKLW D +A S E+L DY+D+++IH P
Sbjct: 60 KNCSVPREEMFLSTKLWPVDCGDEVYNAFQTSCEKLQTDYLDMYMIHMP----------- 108
Query: 125 LLKYPTPGIKPQIDTEDWSFIKTWELMQTLPKTGK---------------TRAVGV---- 165
+ P I Q +T++ KTW M+ L + GK T + +
Sbjct: 109 --QLP-DWIVNQKETKE----KTWRQMELLYEDGKFGFCFKCFKLAFGEATSYIALKISC 161
Query: 166 ---------------------SNFSI---------------KNLEDLLNSSPDVLVPAVN 189
+NF+I ++L++LL + ++P N
Sbjct: 162 NELCKLNLKLPMSISRSKNPQTNFTIITEHVRSIGVSNYSIEDLDELLEFAS--ILPHAN 219
Query: 190 QFEIHPQLPQTELINYCKSKGIVVEAYCPLGSSSSAMLSDPTIAEIADKYHVKPANVLIN 249
Q E+HP Q +L NYC GI+ YCPL + L D T+ +IA KY PA + +
Sbjct: 220 QVELHPWFHQADLKNYCDELGILTMGYCPL--AKGKYLEDETLCKIASKYQKSPAQICLR 277
Query: 250 WGISRGYCVLPKSFTPARIASNKT--PVHLSREDTERITKLS 289
W I + +PKS R+ N LS ED + S
Sbjct: 278 WSIQQNVPTVPKSTDCRRLKENTNVFDFELSAEDMNTLNSFS 319
>CE06112 [R] KOG1577 Aldo/keto reductase family proteins
Length = 301
Score = 118 bits (296), Expect = 9e-27
Identities = 75/270 (27%), Positives = 134/270 (48%), Gaps = 23/270 (8%)
Query: 10 SLKLNTGASIPQLGFG-TWPSSHADAYTAVITALKTGYRHIDAAAMYGNEAAVGKGIR-- 66
+ K + G +P++G G + + D ++ ALK+GYR D A +Y NE +G ++
Sbjct: 11 AFKFSDGYEMPKIGLGISRIETQQDLDVSIEAALKSGYRQFDTANLYKNETFLGNSLKKY 70
Query: 67 --DSGIPREEIFVTTKLWNTQQR---DPASALDESLERLGLDYVDLFLIHWPVPLKPVGG 121
G+ RE++F+TTK+ + + L SL L DYVDL LIH+P + G
Sbjct: 71 LPQFGLTREDVFITTKVRTLNENTVEETEKQLANSLATLQTDYVDLLLIHYPRD-RDTGN 129
Query: 122 PENLLKYPTPGIKPQIDTEDWSFIKTWELMQTLPKTGKTRAVGVSNFSIKNLEDLLNSSP 181
++ Y + +I W+ ++ ++G+ R++GVSN+ + +L ++ +
Sbjct: 130 DDD---YEINKSRRKI---------VWQTLEKAKESGRVRSIGVSNYEVYHLVEMFEYAK 177
Query: 182 DVLVPAVNQFEIHPQLPQTELINYCKSKGIVVEAYCPLGSSSSAMLSDPTIAEIADKYHV 241
+ P +NQ+E P L + L +C IVV++Y L +L + + ++ KY+
Sbjct: 178 --IRPVLNQYEYQPYLTRPTLKKFCDLNNIVVQSYSSLCWGDKEILQEKPLVDLCQKYNQ 235
Query: 242 KPANVLINWGISRGYCVLPKSFTPARIASN 271
P +L + ++PKS TP+RI N
Sbjct: 236 TPQAILYAFAHCSNTSMIPKSATPSRIHDN 265
>SPBC28F2.05c [R] KOG1577 Aldo/keto reductase family proteins
Length = 276
Score = 97.8 bits (242), Expect = 2e-20
Identities = 77/258 (29%), Positives = 128/258 (48%), Gaps = 38/258 (14%)
Query: 21 QLGFGTWPSSHADAYTAVITALKTGYRHIDAAAMYGNEAAVGKGIRDS-----GIPREEI 75
QL FG + D Y VI AL G R ID+A Y NE + I+D I RE+I
Sbjct: 15 QLCFGVYQLK--DCYQQVIEALSLGIRVIDSAITYRNEKECEQAIQDFCHQNVNIKREDI 72
Query: 76 FVTTKLWNTQQRDPAS--ALDESLERLGLDYVDLFLIHWPVPLKPVGGPENLLKYPTPGI 133
+ TK+ ++ Q + A+++SL R G +D+ LIH P K+P I
Sbjct: 73 TLITKIPDSLQGFERTWKAVEQSLRRTGRPKLDVVLIHSP-------------KWPVRRI 119
Query: 134 KPQIDTEDWSFIKTWELMQTLPKTGKTRAVGVSNFSIKNLEDLLNSSPDVLVPAVNQFEI 193
+ +W + K G+ +GVSN++I +LE+++ S + +PA+NQ E
Sbjct: 120 E------------SWRALLQHQKEGRINKIGVSNYNIHHLEEII--SLGLPLPAINQVEF 165
Query: 194 HPQLPQTELINYCKSKGIVVEAYCPLGSSSSAMLSDPTIAEIADKYHVKPANVLINWGIS 253
+ ++YC + GI+V+A+ PL + LSD + +++ KY+ PAN+L+ + +
Sbjct: 166 SAFNNRPTFLSYCFNHGILVQAFSPL--TRGYRLSDIRLLDLSLKYNKTPANILLRYCLQ 223
Query: 254 RGYCVLPKSFTPARIASN 271
+G + K+ + I N
Sbjct: 224 KGVSPIFKASSFVHIHEN 241
>Hs20537171 [R] KOG1577 Aldo/keto reductase family proteins
Length = 241
Score = 93.2 bits (230), Expect = 4e-19
Identities = 79/271 (29%), Positives = 109/271 (40%), Gaps = 76/271 (28%)
Query: 13 LNTGASIPQLGFGTWPSSHADAYTAVITALKTGYRHIDAAAMYGNEAAVGKGI----RDS 68
LN G +P LG GTW S AV A+ GY HID A +Y NE VG I R+
Sbjct: 7 LNNGTKMPILGLGTWNSPPGQVTEAVKVAINVGYCHIDCAHVYQNENDVGVAIREKLREQ 66
Query: 69 GIPREEIFVTTKLWNTQQRDPASALDESLERLGLDYVDLFLIHWPVPLKPVGGPENLLKY 128
+ EE+F+T+KL ++ P+ P N
Sbjct: 67 VVKCEELFITSKLCFKPGKE---------------------------FFPLDEPGNGNVV 99
Query: 129 PTPGIKPQIDTEDWSFIKTWELMQTLPKTGKTRAVGVSNFSIKNLEDLLNSSPDVLVPAV 188
P+ + + + TW M+ L G +A+G+SNF+
Sbjct: 100 PS----------NSNILDTWAGMEELVDEGLVKAIGISNFNHL----------------- 132
Query: 189 NQFEIHPQLPQTELINYCKSKGIVVEAYCPLGS--------SSSAMLSDPTIAEIADKYH 240
Q +LI YC+SKGI+V AY S ++L DP I I K++
Sbjct: 133 ----------QEKLIQYCQSKGIMVTAYSSFSSPDRPWAKPEDPSLLEDPRIKAITAKHN 182
Query: 241 VKPANVLINWGISRGYCVLPKSFTPARIASN 271
A VLI + + R V+PKS TP IA N
Sbjct: 183 KTTAQVLIWFPMQRNLVVIPKSVTPECIAEN 213
>Hs16156291 [R] KOG1577 Aldo/keto reductase family proteins
Length = 130
Score = 87.0 bits (214), Expect = 3e-17
Identities = 50/118 (42%), Positives = 73/118 (61%), Gaps = 9/118 (7%)
Query: 10 SLKLNTGASIPQLGFGTWPS---SHADAYTAVITALKTGYRHIDAAAMYGNEAAVGKGIR 66
S+KLN G +P LGFGT + + ++ AV A+ GYRHID+A + NE +G+ IR
Sbjct: 8 SVKLNDGKFMPILGFGTSVARKVAMSNVEEAVQVAIDVGYRHIDSAYTHLNEEGIGQAIR 67
Query: 67 ----DSGIPREEIFVTTKLWNTQQRDPA--SALDESLERLGLDYVDLFLIHWPVPLKP 118
+ + R++IF TTK+W T R L+ SL++L L Y+DL+L H+PVPL+P
Sbjct: 68 KKIANGTVKRKDIFYTTKVWGTFSRPELVQRGLEMSLKKLQLSYMDLYLFHFPVPLQP 125
>At4g33670 [C] KOG1576 Predicted oxidoreductase
Length = 319
Score = 68.9 bits (167), Expect = 9e-12
Identities = 61/224 (27%), Positives = 94/224 (41%), Gaps = 40/224 (17%)
Query: 14 NTGASIPQLGFGT-------WPSSHADAYTAVITALKTGYRHIDAAAMYG---NEAAVGK 63
NTG + +GFG P + DA V A + G D + YG +E +GK
Sbjct: 11 NTGLKVSAVGFGASPLGSVFGPVAEDDAVATVREAFRLGINFFDTSPYYGGTLSEKMLGK 70
Query: 64 GIRDSGIPREEIFVTTKLWNTQQRDPASA------LDESLERLGLDYVDLFLIHWPVPLK 117
G++ +PR + V TK ++ SA +DESLERL LDYVD+ H
Sbjct: 71 GLKALQVPRSDYIVATKCGRYKEGFDFSAERVRKSIDESLERLQLDYVDILHCH------ 124
Query: 118 PVGGPENLLKYPTPGIKPQIDTEDWSFIKTWELMQTLPKTGKTRAVGVSNFSIKNLEDLL 177
+ + D +T +Q L + GKTR +G++ + +L
Sbjct: 125 ----------------DIEFGSLDQIVSETIPALQKLKQEGKTRFIGITGLPLDIFTYVL 168
Query: 178 NSSPDVLVPAVNQFEIHPQLPQT--ELINYCKSKGIVVEAYCPL 219
+ P V + + + T +L+ Y KSKG+ V + PL
Sbjct: 169 DRVPPGTVDVILSYCHYGVNDSTLLDLLPYLKSKGVGVISASPL 212
>CE06775 [R] KOG1577 Aldo/keto reductase family proteins
Length = 134
Score = 60.5 bits (145), Expect = 3e-09
Identities = 31/77 (40%), Positives = 46/77 (59%), Gaps = 4/77 (5%)
Query: 11 LKLNTGASIPQLGFGTWPSSHADAYTAVITALKTGYRHIDAAAMYGNEAAVGKGIR---- 66
L L+ S+P +G GTW S+ D +AV A+K GY ID A+ Y NE +G I+
Sbjct: 48 LTLSNAHSMPAVGLGTWQSNAEDVISAVKAAVKNGYSLIDTASGYNNEEFIGTAIKEVIA 107
Query: 67 DSGIPREEIFVTTKLWN 83
+ + RE++F+TTK+ N
Sbjct: 108 EGVVKREDLFITTKVPN 124
>Hs22058392 [R] KOG1577 Aldo/keto reductase family proteins
Length = 156
Score = 57.8 bits (138), Expect = 2e-08
Identities = 46/162 (28%), Positives = 69/162 (42%), Gaps = 18/162 (11%)
Query: 151 MQTLPKTGKTRAVGVSNFSIKNLEDLLNSSPDVLVPAVNQFEIHPQLPQTELINYCKSKG 210
M+ L G +A+G+S F+ ++ +LN P V + E L Q +LI YC+SKG
Sbjct: 1 MKELVDEGLVKAIGISKFNYSHVRRILNKRGLKYQPMVKEIEFCTYLTQKKLIQYCQSKG 60
Query: 211 IVVEAYCPLGS--------SSSAMLSDPTIAEIADKYHVKPANVLINWGISRGYCVLPKS 262
I+V AY PL S++L D I K++ A R V PKS
Sbjct: 61 IMVTAYSPLDCLDRPWAKLKDSSVLEDARSKVITVKHNKTTA--------QRNLVVNPKS 112
Query: 263 FTPARIASNKTPVH--LSREDTERITKLSETLGVKRYVHPDF 302
T IA N + LS +D + + +K + +
Sbjct: 113 VTQKCIAENFKAFYFELSSKDMTTLPSYNRNCALKHLYYQGY 154
>Hs22060498 [R] KOG1577 Aldo/keto reductase family proteins
Length = 594
Score = 57.4 bits (137), Expect = 3e-08
Identities = 42/129 (32%), Positives = 58/129 (44%), Gaps = 16/129 (12%)
Query: 151 MQTLPKTGKTRAVGVSNFSIKNLEDLLNSSPDVLVPAVNQFEIHPQLPQTELINYCKSKG 210
M+ L G +A+G+S F+ ++ +LN P V + E L Q +LI YC+SKG
Sbjct: 1 MKELVDEGLVKAIGISKFNYSHVRRILNKRGLKYQPMVKEIEFCTYLTQKKLIQYCQSKG 60
Query: 211 IVVEAYCPLGS--------SSSAMLSDPTIAEIADKYHVKPANVLINWGISRGYCVLPKS 262
I+V AY PL S++L D I K++ A R V PKS
Sbjct: 61 IMVTAYSPLDCLDRPWAKLKDSSVLEDARSKVITVKHNKTTA--------QRNLVVNPKS 112
Query: 263 FTPARIASN 271
T IA N
Sbjct: 113 VTQKCIAEN 121
>At5g53580 [C] KOG1575 Voltage-gated shaker-like K+ channel subunit beta/KCNAB
Length = 324
Score = 57.4 bits (137), Expect = 3e-08
Identities = 75/296 (25%), Positives = 112/296 (37%), Gaps = 75/296 (25%)
Query: 18 SIPQLGFGTWP-----------SSHADAYTAVITALKTGYRHIDAAAMYG-------NEA 59
S+ +GFGTW S A AL+ G D A YG +E
Sbjct: 5 SVSPMGFGTWAWGNQLLWGYQTSMDDQLQQAFELALENGINLFDTADSYGTGRLNGQSER 64
Query: 60 AVGKGIRDS-GIP--REEIFVTTKL----WNTQQRDPASALDESLERLGLDYVDLFLIHW 112
+GK I++S G+ + E+ V TK W +A SL+RL +D + + +HW
Sbjct: 65 LLGKFIKESQGLKGKQNEVVVATKFAAYPWRLTSGQFVNACRASLDRLQIDQLGIGQLHW 124
Query: 113 PVPLKPVGGPENLLKYPTPGIKPQIDTEDWSFIKTWELMQTLPKTGKTRAVGVSNF---S 169
T P + + W+ + + + G RAVGVSN+
Sbjct: 125 S----------------TASYAPLQE------LVLWDGLVQMYEKGLVRAVGVSNYGPQQ 162
Query: 170 IKNLEDLLNSSPDVLVPAVNQFEIHPQ-LPQTELINYCKSKGIVVEAYCPLG-------S 221
+ + D L + L A QF + Q E+ + C GI + +Y PLG
Sbjct: 163 LVKIHDYLKTRGVPLCSAQVQFSLLSMGKEQLEIKSICDELGIRLISYSPLGLGMLTGKY 222
Query: 222 SSSAMLSDP-----------------TIAEIADKYHVKPANVLINWGISRGYCVLP 260
SSS + + P ++EIA K V INW I +G +P
Sbjct: 223 SSSKLPTGPRSLLFRQILPGLEPLLLALSEIAKKRGKTMPQVAINWCICKGTVPIP 278
>SPAC1F7.12 [C] KOG1575 Voltage-gated shaker-like K+ channel subunit beta/KCNAB
Length = 340
Score = 56.6 bits (135), Expect = 4e-08
Identities = 58/230 (25%), Positives = 94/230 (40%), Gaps = 57/230 (24%)
Query: 18 SIPQLGFGTW-------PSSHADAYTAVIT-ALKTGYRHIDAAAMYG---NEAAVGKGIR 66
++P +GFG PSS +A AV+T A G D++ MYG NE +G+ +
Sbjct: 12 TVPAIGFGCMGLHAMYGPSSE-EANQAVLTHAADLGCTFWDSSDMYGFGANEECIGRWFK 70
Query: 67 DSGIPREEIFVTTKLW------------NTQQRDPASALDESLERLGLDYVDLFLIH--- 111
+G R+EIF+ TK N + ALD SL+RLG+D +DL+ +H
Sbjct: 71 QTG-RRKEIFLATKFGYEKNPETGELSLNNEPDYIEKALDLSLKRLGIDCIDLYYVHRFS 129
Query: 112 WPVPLKPVGGPENLLKYPTPGIKPQIDTEDWSFIKTWELMQTLPKTGKTRAVGVSNFSIK 171
P++ + G ++ + GK R +G+S S
Sbjct: 130 GETPIEKIMG----------------------------ALKKCVEAGKIRYIGLSECSAN 161
Query: 172 NLEDLLNSSPDVLVPA-VNQFEIHPQLPQTELINYCKSKGIVVEAYCPLG 220
+ P V + F + + P+ ++ C+ I + Y PLG
Sbjct: 162 TIRRAAAVYPVSAVQVEYSPFSLEIERPEIGVMKACRENNITIVCYAPLG 211
>At1g04420 [C] KOG1575 Voltage-gated shaker-like K+ channel subunit beta/KCNAB
Length = 412
Score = 53.5 bits (127), Expect = 4e-07
Identities = 40/139 (28%), Positives = 66/139 (46%), Gaps = 15/139 (10%)
Query: 92 ALDESLERLGLDYVDLFLIHWPVPLKPVGGPENLLKYPTPGIKPQIDTEDWSFIKTWELM 151
++++SL+RLG DY+DL IHWP P+ G Y T +P + F +
Sbjct: 169 SVEKSLKRLGTDYIDLLQIHWPDRYVPLFGD---FYYETSKWRPSV-----PFAEQLRAF 220
Query: 152 QTLPKTGKTRAVGVSNFSIKNLEDLLNSSPDVLVPAVNQFEIHPQL-----PQTELINYC 206
Q L GK R +GVSN + + + +N++ +P + + L + +L+ C
Sbjct: 221 QDLIVEGKVRYIGVSNETSYGVTEFVNTAKLEGLPKIVSIQNGYSLLVRCRYEVDLVEVC 280
Query: 207 --KSKGIVVEAYCPLGSSS 223
K+ + + AY PLG S
Sbjct: 281 HPKNCNVGLLAYSPLGGGS 299
>SPCC965.06 [C] KOG1575 Voltage-gated shaker-like K+ channel subunit beta/KCNAB
Length = 344
Score = 49.3 bits (116), Expect = 7e-06
Identities = 37/125 (29%), Positives = 55/125 (43%), Gaps = 20/125 (16%)
Query: 15 TGASIPQLGFGTWPSSHADAYTAVIT------ALKTGYRHIDAAAMYGN---EAAVGKGI 65
+G + G W + + Y T A G D A +Y N E +GK I
Sbjct: 21 SGLKVSAFSLGGWLTYGNEGYDVEHTKNCLKQAWDLGINTFDTAEIYSNGNSETVMGKAI 80
Query: 66 RDSGIPREEIFVTTKLW--------NT---QQRDPASALDESLERLGLDYVDLFLIHWPV 114
++ G R E +TTK++ NT ++ L+ SL+RLGL YVD+ + H P
Sbjct: 81 KELGWDRSEYVITTKVFFGAGTKLPNTTGLSRKHIIEGLNASLKRLGLPYVDVIMAHRPD 140
Query: 115 PLKPV 119
P P+
Sbjct: 141 PSVPM 145
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.316 0.135 0.409
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,097,399
Number of Sequences: 60738
Number of extensions: 909072
Number of successful extensions: 2308
Number of sequences better than 1.0e-05: 67
Number of HSP's better than 0.0 without gapping: 50
Number of HSP's successfully gapped in prelim test: 17
Number of HSP's that attempted gapping in prelim test: 1982
Number of HSP's gapped (non-prelim): 77
length of query: 309
length of database: 30,389,216
effective HSP length: 106
effective length of query: 203
effective length of database: 23,950,988
effective search space: 4862050564
effective search space used: 4862050564
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)