ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIV2511 good G KOG2504 Carbohydrate transport and metabolism Monocarboxylate transporter
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIV2511 857342 855954 -463
(463 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YKL221w [G] KOG2504 Monocarboxylate transporter 397 e-110
YNL125c [G] KOG2504 Monocarboxylate transporter 172 1e-42
YOR306c [G] KOG2504 Monocarboxylate transporter 69 2e-11
YOL119c [G] KOG2504 Monocarboxylate transporter 66 1e-10
Hs18699730 [G] KOG2504 Monocarboxylate transporter 64 4e-10
Hs22064599 [G] KOG2504 Monocarboxylate transporter 61 3e-09
7292012 [G] KOG2504 Monocarboxylate transporter 59 1e-08
Hs4759112 [G] KOG2504 Monocarboxylate transporter 59 2e-08
Hs4759120 [G] KOG2504 Monocarboxylate transporter 55 2e-07
Hs7019529 [G] KOG2504 Monocarboxylate transporter 54 6e-07
7290288 [G] KOG2504 Monocarboxylate transporter 53 1e-06
Hs4759118 [G] KOG2504 Monocarboxylate transporter 52 2e-06
>YKL221w [G] KOG2504 Monocarboxylate transporter
Length = 473
Score = 397 bits (1021), Expect = e-110
Identities = 205/439 (46%), Positives = 269/439 (60%), Gaps = 14/439 (3%)
Query: 11 TEKTIQIPDGGYGWVITFAFFLYNFCTWGANAGYAVYLATYLSRDVFPGGGKLDYXXXXX 70
T +I++PDGGYGW I AF LYNF TWGAN+GYA+YLA YL + F GG KLDY
Sbjct: 29 TSISIEVPDGGYGWFILLAFILYNFSTWGANSGYAIYLAHYLENNTFAGGSKLDYASIGG 88
Query: 71 XXXXXXXXXXPVIIYFSRNYGVHVVIGLGIICQCXXXXXXXFSKKLWQIYLTQGLLISFG 130
PVI + + + +IGLGI+ Q FS LW+IYLTQG+LI FG
Sbjct: 89 LAFSCGLFFAPVITWLYHIFSIQFIIGLGILFQGAALLLAAFSVTLWEIYLTQGVLIGFG 148
Query: 131 LALICTPSMGLIPQWFRKRRTXXXXXXXXXXXXXXXXXXXXMQKIIEVKSVKWALIVQCI 190
LA I PS+ LIP WFR +R+ MQ I++ + VKWALI QCI
Sbjct: 149 LAFIFIPSVTLIPLWFRNKRSLASGIGTAGSGLGGIVFNLGMQSILQKRGVKWALIAQCI 208
Query: 191 ICTSLSTLALILTRTRNQHIHGSAEQTQPLGAAFKEHISVFKVVG---MWALCSWVSFTM 247
ICTSLST+AL+LTRT +Q + ++K + + V+ +W L +VSF M
Sbjct: 209 ICTSLSTIALMLTRTTHQGLRQHKR-------SYKFELLDYDVLSNFAVWLLFGFVSFAM 261
Query: 248 LGYVILLYSLSAFTQSLGYDSEEGSYVSCMISVGSLIGRPLIGHIADRYGPITVGALVNL 307
LGYV+LLYSLS FT SLGY S++GSYVSCM+SVGSL+GRP++GHIAD+YG +TVG +++L
Sbjct: 262 LGYVVLLYSLSDFTVSLGYTSKQGSYVSCMVSVGSLLGRPIVGHIADKYGSLTVGMILHL 321
Query: 308 VVAILCWAMWIPCRSLSVAIVFALLQGGLMGTVWVIFGSATARVVGLKKIDKAFSVMWIF 367
V+AILCWAMWIPC++L+ AI F LL G +MGT+W S R+VGL+K+ F WIF
Sbjct: 322 VMAILCWAMWIPCKNLATAIRFGLLVGSIMGTIWPTIASIVTRIVGLQKLPGTFGSTWIF 381
Query: 368 IALFGIPAPVIGLQLRSNVANSKTNYEKTXXXXXXXXXXXXXXXXXXXXYILSRDKVASI 427
+A F + AP+IGL+LRS N +Y +T +I++RD++A
Sbjct: 382 MAAFALVAPIIGLELRSTDTNG-NDYYRTAIFVGFAYFGVSLCQWLLRGFIIARDEIAVR 440
Query: 428 HAKGEDSMDHDETHYSVTL 446
A S D +E H +V L
Sbjct: 441 EAY---SADQNELHLNVKL 456
>YNL125c [G] KOG2504 Monocarboxylate transporter
Length = 673
Score = 172 bits (436), Expect = 1e-42
Identities = 105/377 (27%), Positives = 173/377 (45%), Gaps = 14/377 (3%)
Query: 6 KKPSVTEKTIQI---PDGGYGWVITFAFFLYNFCTWGANAGYAVYLATYLSRDVFPGGGK 62
KK + T Q+ PDGGYGWV+TF FL F TWG NA + V LA YL+ D +PG K
Sbjct: 192 KKVFTNKSTGQLELPPDGGYGWVVTFCVFLTMFSTWGCNASFGVDLAYYLNHDTYPGASK 251
Query: 63 LDYXXXXXXXXXXXXXXXPVIIYFSRNYGVHVVIGLGIICQCXXXXXXXFSKKLWQIYLT 122
DY P+++ R G+ + G F+ KLWQ+Y+T
Sbjct: 252 YDYALIAGLTVFLGQLLSPLVMALMRIIGLRTTMLFGDAVMLAAYLLASFTTKLWQLYVT 311
Query: 123 QGLLISFGLALICTPSMGLIPQWFRKRRTXXXXXXXXXXXXXXXXXXXXMQKII-EVKSV 181
QG ++ ++LI P+ ++P WF K+R K++ + +
Sbjct: 312 QGFMVGCSISLIFVPATTVLPGWFLKKRAVAMGVSLLGTGAGGVVYGLATNKMLSDFGNT 371
Query: 182 KWALIVQCIICTSLSTLALILTRTRNQ----HIHGSAEQTQPLGAAFKEHISVFKVVGMW 237
+W L + I C+ +A+ L + RN + + L A F + V +
Sbjct: 372 RWCLRIIGISCSISVLVAIALLKERNPTPAIGLKSPRAMFEQLKAMFSLKVITKPFVVLI 431
Query: 238 ALCSWVSFTMLGYVILLYSLSAFTQSLGYDSEEGSYVSCMISVGSLIGRPLIGHIADRYG 297
AL W F + Y +++++LS++ S G S + S ++ +++ IGRPL+G D++G
Sbjct: 432 AL--WFMFALFAYNMMVFTLSSYAISKGLSSHDASTLTAILNGSQSIGRPLMGLAGDKFG 489
Query: 298 PITVGALVNLVVAILCWAMWIPCRSLSVAIVFALLQGGLMGTVWVIFGSATARVVGLKKI 357
V ++ ++ I +A WIP + I F++L G +G V+ T + + K
Sbjct: 490 RANVTIVLTTLLTIYMFAFWIPAHTFVQLIFFSILVGSCVGVANVM---NTVLIADMVKP 546
Query: 358 DKAFSVMWIFIALFGIP 374
++ F W F+ G P
Sbjct: 547 EE-FLPAWAFVNYCGAP 562
>YOR306c [G] KOG2504 Monocarboxylate transporter
Length = 521
Score = 68.6 bits (166), Expect = 2e-11
Identities = 81/414 (19%), Positives = 162/414 (38%), Gaps = 39/414 (9%)
Query: 3 DLEKKPSVTEKTIQIPDGGY-GWVITFAFFLYNFCTWGANAGYAVYLATYLSRDVFPGGG 61
D +K+ E+ P+GG+ WV+TF FL +G V + ++L +D
Sbjct: 85 DSDKEEDSNEEIESFPEGGFKAWVVTFGCFLGLIACFGLLNSTGV-IESHL-QDNQLSSE 142
Query: 62 KLDYXXXXXXXXXXXXXXXPVI--IYFSRNYGVHVVIGLGIICQCXXXXXXXFSKKLWQI 119
+ +I YF RN G ++ +G + S K W
Sbjct: 143 SVSTIGWLFSLFLFVCSASCIISGTYFDRN-GFRTIMIVGTVFHVAGLFATANSTKYWHF 201
Query: 120 YLTQGLLISFGLALICTPSMGLIPQWFRKRRTXXXXXXXXXXXXXXXXXXXXMQKIIEVK 179
L+ ++ FG ++ +P + + +F KRR ++ +K
Sbjct: 202 ILSFAIVCGFGNGIVLSPLVSVPAHYFFKRRGTALAMATIGGSVGGVVFPIMLRSFFSMK 261
Query: 180 S-------VKWALIVQCIICTSLSTLALILTRTRNQHIHGSAEQTQPL------------ 220
S W + + +L TL++IL + R H+ +++ +
Sbjct: 262 SDTDPTYGFVWGIRTLGFLDLALLTLSIILVKERLPHVIENSKDGESRWRYILRVYILQC 321
Query: 221 --GAAFKEHISVFKVVGMWALCSWVSFTMLGYVILLYSLSAFTQSLGYDSEEGSYVSCMI 278
AF + +F V+G F+ L L ++ S G + + + +I
Sbjct: 322 FDAKAFLDMKYLFCVLG-------TVFSELSINSALTYYGSYATSHGISANDAYTLIMII 374
Query: 279 SVGSLIGRPLIGHIADRYGPITVGALVNLVVAILCWAMWIPC-RSLSVAIVFALLQGGLM 337
+V + GR + G+++D++G V L + I+ + W+P +L+ V + L G
Sbjct: 375 NVCGIPGRWVPGYLSDKFGRFNVAIATLLTLFIVMFVGWLPFGTNLTNMYVISALYGFCS 434
Query: 338 GTVWVIFGSATARVVGLKKIDKAFSVMWIFIALFGIPAPVIGLQLRSNVANSKT 391
G+V+ + ++ ++ K +S M+ F+ FG ++G+ + + + KT
Sbjct: 435 GSVFSLLPVCCGQISKTEEFGKRYSTMY-FVVGFG---TLVGIPITGAIISIKT 484
>YOL119c [G] KOG2504 Monocarboxylate transporter
Length = 501
Score = 66.2 bits (160), Expect = 1e-10
Identities = 69/327 (21%), Positives = 127/327 (38%), Gaps = 40/327 (12%)
Query: 85 YFSRNYGVHVVIGLGIICQCXXXXXXXFSKKLWQIYLTQGLLISFGLALICTPSMGLIPQ 144
YF RN + ++ G + K +WQ L + G ++ TP +G +
Sbjct: 158 YFDRNGSIGLMC-TGTVIYAGGLFALANCKSVWQFILAFSVCSGLGTGILMTPLIGTVAT 216
Query: 145 WFRKRRTXXXXXXXXXXXXXXXXXXXXMQKIIEVKSVKWALIVQCIICTSLSTLALILTR 204
WF KRR ++K+ + +WA+ + IC + A +L R
Sbjct: 217 WFLKRRGIATSISTMGGSIGGIVFPIMLRKLYKEVGFQWAIRILSFICLTCLICASVLAR 276
Query: 205 TRNQHIHGSAEQTQPLGAAFKEHISV------------------FKVVGMWALCSWVSFT 246
E+T+P+ FK V F V + A + S T
Sbjct: 277 ----------ERTKPVVQPFKSKAEVAKWYISSVFNWRYFLEGKFLFVAIGASFAESSLT 326
Query: 247 MLGYVILLYSLS-AFTQSLGYDSEEGSYVSCMISVGSLIGRPLIGHIADRY-GPITVGAL 304
+ YS++ T+++ Y + ++ +VG ++GR + G+ AD++ G V +
Sbjct: 327 SCATYLASYSMTRGNTENVAY-----TMITASNAVG-ILGRYIPGYFADKFIGRFNVEII 380
Query: 305 VNLVVAILCWAMWIPC-RSLSVAIVFALLQGGLMGTVWVIFGSATARVVGLKKIDKAFSV 363
+ A+ + MW+P + V + L G G++ + ++ K ++
Sbjct: 381 TISMAALFNFVMWLPFGGNTKVLWAYVCLWGFSTGSILSLTPVCIGQISKTTDFGKRYAT 440
Query: 364 MWIFIALFGIPAPVIGLQL--RSNVAN 388
+++ AL IP IG L + VAN
Sbjct: 441 VYLLQALVTIPVLPIGGTLIGKGTVAN 467
>Hs18699730 [G] KOG2504 Monocarboxylate transporter
Length = 515
Score = 64.3 bits (155), Expect = 4e-10
Identities = 77/378 (20%), Positives = 133/378 (34%), Gaps = 17/378 (4%)
Query: 18 PDGGYGWVITFAFFLYNFCTWGANAGYAVYLATYLSRDVFPGGGKLDYXXXXXXXXXXXX 77
P+GG+GW++ A N +G V + L K+ +
Sbjct: 65 PEGGWGWLVMLAAMWCNGSVFGIQNACGVLFVSMLETFGSKDDDKMVFKTAWVGSLSMGM 124
Query: 78 XXX--PVIIYFSRNYGVHVVIGLGIICQCXXXXXXXFSKKLWQIYLTQGLLISFGLALIC 135
P++ F+ +G +G F + +YLT G++ + G +
Sbjct: 125 IFFCCPIVSVFTDLFGCRKTAVVGAAVGFVGLMSSSFVSSIEPLYLTYGIIFACGCSFAY 184
Query: 136 TPSMGLIPQWFRKRRTXXXXXXXXXXXXXXXXXXXXMQKIIEVKSVKWALIVQCIICTSL 195
PS+ ++ +F+KR ++ +I+ + + L V CI L
Sbjct: 185 QPSLVILGHYFKKRLGLVNGIVTAGSSVFTILLPLLLRVLIDSVGLFYTLRVLCIFMFVL 244
Query: 196 ----STLALILTRTRNQHIHGSA------EQTQPLGAAFKEHISVFKVVGMWALCSWVSF 245
T + T T+++ GS ++ P F + ++FKV +
Sbjct: 245 FLAGFTYRPLATSTKDKESGGSGSSLFSRKKFSPPKKIF--NFAIFKVTAYAVWAVGIPL 302
Query: 246 TMLGYVILLYSLSAFTQSLGYDSEEGSYVSCMISVGSLIGRPLIGHIADRY-GPITVGAL 304
+ GY + L D + V I V S +GR L G IAD G V
Sbjct: 303 ALFGYFVPYVHLMKHVNERFQDEKNKEVVLMCIGVTSGVGRLLFGRIADYVPGVKKVYLQ 362
Query: 305 VNLVVAILCWAMWIP-CRSLSVAIVFALLQGGLMGTVWVIFGSATARVVGLKKIDKAFSV 363
V I +M IP C I L+ G G I +VG + + +A
Sbjct: 363 VLSFFFIGLMSMMIPLCSIFGALIAVCLIMGLFDGCFISIMAPIAFELVGAQDVSQAIGF 422
Query: 364 MWIFIAL-FGIPAPVIGL 380
+ F+++ + P+ GL
Sbjct: 423 LLGFMSIPMTVGPPIAGL 440
>Hs22064599 [G] KOG2504 Monocarboxylate transporter
Length = 579
Score = 61.2 bits (147), Expect = 3e-09
Identities = 78/394 (19%), Positives = 145/394 (36%), Gaps = 35/394 (8%)
Query: 18 PDGGYGWVITFAFFLYNFCTWGANAGYAVY---LATYLSRDVFPGGGKLDYXXXXXXXXX 74
PDGG+GWV+ A F N ++G + LA + R D
Sbjct: 141 PDGGWGWVVAAAAFAINGLSYGLLRSLGLAFPDLAEHFDRSA------QDTAWISALALA 194
Query: 75 XXXXXXPVIIYFSRNYGVHVVIGLGIICQCXXXXXXXFSKKLWQIYLTQGLLISFGLALI 134
PV S +G V+ +G + F+ L +YL GLL FG AL+
Sbjct: 195 VQQAASPVGSALSTRWGARPVVMVGGVLASLGFVFSAFASDLLHLYLGLGLLAGFGWALV 254
Query: 135 CTPSMGLIPQWFRKRRTXXXXXXXXXXXXXXXXXXXXMQKIIEVKSVKWALIVQCIICTS 194
P++G + ++F +RR +Q +++ + AL++ I
Sbjct: 255 FAPALGTLSRYFSRRRVLAVGLALTGNGASSLLLAPALQLLLDTFGWRGALLLLGAITLH 314
Query: 195 LSTLALILTRTRNQHIHGS--AEQTQPLGAAFKEHISVFKVVGMWALCSWVSFTMLGYVI 252
L+ +L + G A PL A +S+F + GY +
Sbjct: 315 LTPCGALLLPL---VLPGDPPAPPRSPLAAL---GLSLFTRRAFSIFALGTALVGGGYFV 368
Query: 253 LLYSLSAFTQSLGYDSEEGSYVSCMISVGSLIGRPLIGHIADRYGPITVGALVNLVVAIL 312
L+ G + V + ++G R + G +AD+ G + + L+ + A+
Sbjct: 369 PYVHLAPHALDRGLGGYGAALVVAVAAMGDAGARLVCGWLADQ-GWVPLPRLLAVFGALT 427
Query: 313 CWAMW----IPCRS---------LSVAIVFALLQGGLMGTVWVIFGSATARVVGLKKIDK 359
+W +P L+ A+ + L G V+ + +VG+ + +
Sbjct: 428 GLGLWVVGLVPVVGGEESWGGPLLAAAVAYGLSAGSYAPLVFGVLPG----LVGVGGVVQ 483
Query: 360 AFSVMWIFIALFGIPAPVIGLQLRSNVANSKTNY 393
A ++ + ++L G+ P + LR + ++
Sbjct: 484 ATGLVMMLMSLGGLLGPPLSGFLRDETGDFTASF 517
>7292012 [G] KOG2504 Monocarboxylate transporter
Length = 816
Score = 59.3 bits (142), Expect = 1e-08
Identities = 34/134 (25%), Positives = 55/134 (40%), Gaps = 3/134 (2%)
Query: 18 PDGGYGWVITFAFFLYNFCTWGANAGYAVYLATYLSRDVFPGGGKLDYXXXXXXXXXXXX 77
PDGGYGWVI FA F+ N G + ++L +++ + GK
Sbjct: 72 PDGGYGWVICFASFMCNMIVDGIAYTFGIFLEEFVA---YFHEGKGTVAWVGSLLSGVYL 128
Query: 78 XXXPVIIYFSRNYGVHVVIGLGIICQCXXXXXXXFSKKLWQIYLTQGLLISFGLALICTP 137
P++ + YG V G I C FS + + T G + FG +I P
Sbjct: 129 SAGPIVSALANKYGCRAVCIAGSIIACIAFVLSTFSTNVSMLMATYGFMGGFGFGMIYLP 188
Query: 138 SMGLIPQWFRKRRT 151
++ + +F +R+
Sbjct: 189 AVVAVGYYFETKRS 202
>Hs4759112 [G] KOG2504 Monocarboxylate transporter
Length = 465
Score = 58.5 bits (140), Expect = 2e-08
Identities = 69/383 (18%), Positives = 137/383 (35%), Gaps = 33/383 (8%)
Query: 15 IQIPDGGYGWVITFAFFLYNFCTWGANAGYAVYLATYLSRDVFPGGGKLDYXXXXXXXXX 74
++ PDGG+GW + F F+ ++ +V+ + G G D
Sbjct: 13 VKAPDGGWGWAVLFGCFVITGFSYAFPKAVSVFFKELIQEF---GIGYSDTAWISSILLA 69
Query: 75 XXXXXXPVIIYFSRNYGVHVVIGLGIICQCXXXXXXXFSKKLWQIYLTQGLLISFGLALI 134
P+ +G V+ +G + F + + Q+YLT G++ GLAL
Sbjct: 70 MLYGTGPLCSVCVNRFGCRPVMLVGGLFASLGMVAASFCRSIIQVYLTTGVITGLGLALN 129
Query: 135 CTPSMGLIPQWFRKRRTXXXXXXXXXXXXXXXXXXXXMQKIIEVKS------VKWALIVQ 188
PS+ ++ ++F KRR Q + + + L++
Sbjct: 130 FQPSLIMLNRYFSKRRPMANGLAAAGSPVFLCALSPLGQLLQDRYGWRGGFLILGGLLLN 189
Query: 189 CIICTSLSTLALILTRTRNQHIHGSAEQTQPLGAAFKEHISVFKVVGMWALCSWVSFTML 248
C +C +L ++ + GS P + +SVF+ G S +L
Sbjct: 190 CCVCAALMRPLVVTAQP------GSGP---PRPSRRLLDLSVFRDRGFVLYAVAASVMVL 240
Query: 249 GYVILLYSLSAFTQSLGYDSEEGSYVSCMISVGSLIGRPLIGHIADRYGPITVGALVNLV 308
G + + ++ + LG + +++ ++ + RP G +A +G +
Sbjct: 241 GLFVPPVFVVSYAKDLGVPDTKAAFLLTILGFIDIFARPAAGFVAG------LGKVRPYS 294
Query: 309 VAILCWAMWI---------PCRSLSVAIVFALLQGGLMGTVWVIFGSATARVVGLKKIDK 359
V + ++M+ +VF + G G V + +VG K
Sbjct: 295 VYLFSFSMFFNGLADLAGSTAGDYGGLVVFCIFFGISYGMVGALQFEVLMAIVGTHKFSS 354
Query: 360 AFSVMWIFIALFGIPAPVIGLQL 382
A ++ + A+ + P G +L
Sbjct: 355 AIGLVLLMEAVAVLVGPPSGGKL 377
>Hs4759120 [G] KOG2504 Monocarboxylate transporter
Length = 478
Score = 55.1 bits (131), Expect = 2e-07
Identities = 68/371 (18%), Positives = 137/371 (36%), Gaps = 26/371 (7%)
Query: 18 PDGGYGWVITFAFFLYNFCTWGANAGYAVYLATYLSRDVFPGGGKLDYXXXXXXXXXXXX 77
PDGG+GW++ A F+ ++ V+ + +F +
Sbjct: 14 PDGGWGWIVVGAAFISIGFSYAFPKAVTVFFKEI--QQIFHTTYS-EIAWISSIMLAVMY 70
Query: 78 XXXPVIIYFSRNYGVH-VVIGLGIICQCXXXXXXXFSKKLWQIYLTQGLLISFGLALICT 136
PV YG VVI G++C C FS + Q+YLT G + GLA
Sbjct: 71 AGGPVSSVLVNKYGSRPVVIAGGLLC-CLGMVLASFSSSVVQLYLTMGFITGLGLAFNLQ 129
Query: 137 PSMGLIPQWFRKRRTXXXXXXXXXXXXXXXXXXXXMQKIIEVKSVKWALIV-------QC 189
P++ +I ++F ++R Q + K + ++ C
Sbjct: 130 PALTIIGKYFYRKRPMANGLAMAGSPVFLSSLAPFNQYLFNTFGWKGSFLILGSLLLNAC 189
Query: 190 IICTSLSTLALILTRTRNQHIHGSAE-QTQPLGAAFKE----------HISVFKVVGMWA 238
+ + + L T +++++ G E + P K+ S+FK G
Sbjct: 190 VAGSLMRPLGPNQTTSKSKNKTGKTEDDSSPKKIKTKKSTWEKVNKYLDFSLFKHRGFLI 249
Query: 239 LCSWVSFTMLGYVILLYSLSAFTQSLGYDSEEGSYVSCMISVGSLIGRPLIGHIAD-RYG 297
S LG+ + L+ + + G D +++ +++ + RP +G IA+ +Y
Sbjct: 250 YLSGNVIMFLGFFAPIIFLAPYAKDQGIDEYSAAFLLSVMAFVDMFARPSVGLIANSKYI 309
Query: 298 PITVGALVNLVVAI--LCWAMWIPCRSLSVAIVFALLQGGLMGTVWVIFGSATARVVGLK 355
+ + + +C + + + +++A+ G G+V + +VG
Sbjct: 310 RPRIQYFFSFAIMFNGVCHLLCPLAQDYTSLVLYAVFFGLGFGSVSSVLFETLMDLVGAP 369
Query: 356 KIDKAFSVMWI 366
+ A ++ I
Sbjct: 370 RFSSAVGLVTI 380
>Hs7019529 [G] KOG2504 Monocarboxylate transporter
Length = 504
Score = 53.5 bits (127), Expect = 6e-07
Identities = 37/133 (27%), Positives = 56/133 (41%), Gaps = 3/133 (2%)
Query: 18 PDGGYGWVITFAFFLYNFCTWGANAGYAVYLATYLSRDVFPGGGKLDYXXXXXXXXXXXX 77
PDGG+GWV+ A F+ +G +V+ L RD G D
Sbjct: 13 PDGGWGWVVLGACFVVTGFAYGFPKAVSVFFRA-LMRDF--DAGYSDTAWVSSIMLAMLY 69
Query: 78 XXXPVIIYFSRNYGVHVVIGLGIICQCXXXXXXXFSKKLWQIYLTQGLLISFGLALICTP 137
PV +G V+ G + F+ +L ++YLT G+L GLAL P
Sbjct: 70 GTGPVSSILVTRFGCRPVMLAGGLLASAGMILASFATRLLELYLTAGVLTGLGLALNFQP 129
Query: 138 SMGLIPQWFRKRR 150
S+ ++ +F +RR
Sbjct: 130 SLIMLGLYFERRR 142
>7290288 [G] KOG2504 Monocarboxylate transporter
Length = 715
Score = 52.8 bits (125), Expect = 1e-06
Identities = 36/149 (24%), Positives = 60/149 (40%), Gaps = 10/149 (6%)
Query: 3 DLEKKPSVTEKTIQIPDGGYGWVITFAFFLYNFCTWGANAGYAVYLATYLSRDVFPGGGK 62
D+E++P+ PDGG+GWV+ F F+ + T G + ++ +L D F GK
Sbjct: 110 DMERQPTP-------PDGGWGWVVVFGSFMIHIVTDGMTYSFGIFYNEFL--DYF-NEGK 159
Query: 63 LDYXXXXXXXXXXXXXXXPVIIYFSRNYGVHVVIGLGIICQCXXXXXXXFSKKLWQIYLT 122
P+ F YG V G I F++ + + +T
Sbjct: 160 GYTAWIASIMVGVTFSSGPISSSFVNRYGCRAVTIAGSILAASCIIVSMFAQNVLTLIIT 219
Query: 123 QGLLISFGLALICTPSMGLIPQWFRKRRT 151
G G LI P++ + Q+F +R+
Sbjct: 220 IGFGTGLGFGLIYLPAIVSVTQYFEAKRS 248
>Hs4759118 [G] KOG2504 Monocarboxylate transporter
Length = 523
Score = 52.0 bits (123), Expect = 2e-06
Identities = 30/137 (21%), Positives = 60/137 (42%), Gaps = 5/137 (3%)
Query: 16 QIPDGGYGWVITFAFFLYNFCTWGANAGYAVYLATYLSRDVF-PGGGKLDYXXXXXXXXX 74
++PDGG+GW + +FF T+G + V+ + D F ++ +
Sbjct: 17 EVPDGGWGWAVAVSFFFVEVFTYGIIKTFGVFFNDLM--DSFNESNSRISWIISICVFVL 74
Query: 75 XXXXXXPVIIYFSRNYGVHVVIGLGIICQCXXXXXXXFSKKLWQIYLTQGLLISFGLALI 134
P+ S +G +V+ LG + FS+++ +Y+ G++ G
Sbjct: 75 TFSA--PLATVLSNRFGHRLVVMLGGLLVSTGMVAASFSQEVSHMYVAIGIISGLGYCFS 132
Query: 135 CTPSMGLIPQWFRKRRT 151
P++ ++ Q+F KRR+
Sbjct: 133 FLPTVTILSQYFGKRRS 149
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.326 0.140 0.441
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,680,045
Number of Sequences: 60738
Number of extensions: 848152
Number of successful extensions: 2243
Number of sequences better than 1.0e-05: 12
Number of HSP's better than 0.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 2221
Number of HSP's gapped (non-prelim): 17
length of query: 463
length of database: 30,389,216
effective HSP length: 110
effective length of query: 353
effective length of database: 23,708,036
effective search space: 8368936708
effective search space used: 8368936708
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)