ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIV2547 good U KOG2319 Intracellular trafficking, secretion, and vesicular transport Vacuolar assembly/sorting protein VPS9
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIV2547 869444 868134 -437
(437 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YML097c [U] KOG2319 Vacuolar assembly/sorting protein VPS9 360 2e-99
SPBC4F6.10 [U] KOG2319 Vacuolar assembly/sorting protein VPS9 202 6e-52
At5g09320_1 [U] KOG2319 Vacuolar assembly/sorting protein VPS9 127 4e-29
At3g19770 [U] KOG2319 Vacuolar assembly/sorting protein VPS9 123 5e-28
Hs20538500 [U] KOG2319 Vacuolar assembly/sorting protein VPS9 92 1e-18
Hs7657496_3 [U] KOG2319 Vacuolar assembly/sorting protein VPS9 90 6e-18
7292054_2 [U] KOG2319 Vacuolar assembly/sorting protein VPS9 90 6e-18
CE26367 [U] KOG2319 Vacuolar assembly/sorting protein VPS9 72 2e-12
7292625_2 [U] KOG2319 Vacuolar assembly/sorting protein VPS9 63 1e-09
Hs14149803 [U] KOG2319 Vacuolar assembly/sorting protein VPS9 60 8e-09
Hs18466802 [U] KOG2320 RAS effector RIN1 (contains VPS domain) 59 1e-08
HsM13376238 [U] KOG2320 RAS effector RIN1 (contains VPS domain) 57 4e-08
Hs4759040 [U] KOG2320 RAS effector RIN1 (contains VPS domain) 57 4e-08
Hs21314732 [U] KOG2320 RAS effector RIN1 (contains VPS domain) 57 4e-08
CE26468 [U] KOG2319 Vacuolar assembly/sorting protein VPS9 53 8e-07
>YML097c [U] KOG2319 Vacuolar assembly/sorting protein VPS9
Length = 451
Score = 360 bits (925), Expect = 2e-99
Identities = 192/434 (44%), Positives = 276/434 (63%), Gaps = 18/434 (4%)
Query: 5 DDKGFNASPETISEKPLADVGENLDEKNNYYDFQAFLKIMRDPKADPIVKHTKSFIRNFV 64
DD A+ ET + D G+ + +YDFQ F+K ++ P ADP+VK+TKSF+RNF+
Sbjct: 35 DDPNRAAAEETNRDISAQDKGD----EEPFYDFQIFIKQLQTPGADPLVKYTKSFLRNFL 90
Query: 65 SQRENWTTSEQEKLINDFKVFIYDKLLTNEAFRDLSDAQIKNAKEGIEKLVMGKLYYKCF 124
+QR WT SE+ KLI+DFK FIYDK E FR L +++++NAKEG+EKL+MGKLY +CF
Sbjct: 91 AQRLLWTVSEEIKLISDFKTFIYDKFTLYEPFRSLDNSKMRNAKEGMEKLIMGKLYSRCF 150
Query: 125 SPCLVNE-KRSSDATHEQDLLDDAKLRDKILEFRFLGPEHLDIIPDLINGKLHSFIALSA 183
SP L ++ D H +DL +D L +KI +RF+ P LDI + N +L+ F+ L++
Sbjct: 151 SPSLYEILQKPLDDEHMKDLTNDDTLLEKIRHYRFISPIMLDIPDTMPNARLNKFVHLAS 210
Query: 184 KELAKINQYRSPRDKMVCVLNSCKVLFGLLKHNNKLNGGADHFVPLLIFTLLKSDVPHLI 243
KEL KIN+++SPRDKMVCVLN+ KV+FGLLKH GAD F+P+LI+ +LK V +L+
Sbjct: 211 KELGKINRFKSPRDKMVCVLNASKVIFGLLKHTKLEQNGADSFIPVLIYCILKGQVRYLV 270
Query: 244 SNVRYIERFRFPSFLMGENAYYLSTLQGAVNFXXXXXXXXXXXXETDKDFNKKYSQNQEE 303
SNV YIERFR P F+ GE YYLS+LQ A+NF E +DF + Y +N ++
Sbjct: 271 SNVNYIERFRSPDFIRGEEEYYLSSLQAALNF-IMNLTERSLTIEDHEDFEEAYQRNFKQ 329
Query: 304 IKDLKKQELLNPKDSSTKFPHRTVSPSPSEYILKPLDDAANSVLTKLNDFWNXXXXXXXX 363
+ + K++E K + P P+ +LKPLD+ N V++K N+ ++
Sbjct: 330 LAEEKEEE---EKKKQLEIPDEL---QPNGTLLKPLDEVTNIVISKFNELFSPIGEPT-- 381
Query: 364 XXEYEDRSPRDHQEIDEHTATVLAQQMEHKEQENTLQTLQLMFPDLDPDLIRDVCIASKY 423
++ + + Q E + L +++E E+++TL TLQ MFPD+DP LI DVCIA K
Sbjct: 382 ----QEEALKSEQSNKEEDVSSLIKKIEENERKDTLNTLQNMFPDMDPSLIEDVCIAKKS 437
Query: 424 RVGVCVDSLLEMAE 437
R+G CVD+LL ++E
Sbjct: 438 RIGPCVDALLSLSE 451
>SPBC4F6.10 [U] KOG2319 Vacuolar assembly/sorting protein VPS9
Length = 537
Score = 202 bits (515), Expect = 6e-52
Identities = 121/323 (37%), Positives = 186/323 (57%), Gaps = 23/323 (7%)
Query: 10 NASPETISEKPLADV---GENLDEKNN---------YYDFQAFLKIMRDPKADPIVKHTK 57
++ E ++EK D +N+ +NN +DF FL+ +R A+P+ K+ K
Sbjct: 76 SSDQEVMNEKQSLDKENRNDNIPHENNPGQQEINEPIFDFHMFLEQLRSSSAEPVAKYLK 135
Query: 58 SFIRNFVSQRENWTTSEQEKLINDFKVFIYDKLLTNEAFRDLSDAQIKNAKEGIEKLVMG 117
SF+ F +R WT + Q KLI DF FI +K+ E + S A+I NAKEG+EKLV+
Sbjct: 136 SFLSEFTKRR--WTVNYQVKLIRDFLKFINEKIEQYEPWASGSQAEIDNAKEGMEKLVLN 193
Query: 118 KLYYKCFSPCLVNEKRSSDATHEQDLLDDAKLRDKILEFRFLGPEHLDIIPDLINGKLHS 177
+LY FSP + + H D+ +D L +K+ F+++ E+LDI + K
Sbjct: 194 RLYTSLFSPEIAKSGIPLSSEHSDDVEEDRVLSEKMELFQWITEENLDIKKQKSSSK--- 250
Query: 178 FIALSAKELAKINQYRSPRDKMVCVLNSCKVLFGLLKHNNKLNGGADHFVPLLIFTLLKS 237
F L+A EL +IN Y +PRDK++C+LN CKV+F L++ K AD FVP+LIF +L++
Sbjct: 251 FFKLAADELRRINDYHAPRDKIICLLNCCKVIFSYLRNVVK-EESADMFVPILIFVVLQA 309
Query: 238 DVPHLISNVRYIERFRFPSFLMGENAYYLSTLQGAVNFXXXXXXXXXXXXETDKDFNKKY 297
HL+SN++YI+RFR P L GE YYLSTL GA++F T+++FN
Sbjct: 310 RPAHLVSNIQYIQRFRSPEKLTGEVMYYLSTLMGAMSFIETLDCSSLTI--TEEEFN--- 364
Query: 298 SQNQEEIKDLKKQELLNPKDSST 320
+Q ++ IK +++++L +S T
Sbjct: 365 AQIEKSIKKMEERKLSEKSESKT 387
>At5g09320_1 [U] KOG2319 Vacuolar assembly/sorting protein VPS9
Length = 494
Score = 127 bits (318), Expect = 4e-29
Identities = 89/279 (31%), Positives = 140/279 (49%), Gaps = 34/279 (12%)
Query: 26 ENLDEKNNYYDFQAFLKIMRDPKADPIVKHTKSFIRNFVSQRENWTTSEQEK---LINDF 82
EN D + ++F + P A +K KSFI + ++ T + EK + DF
Sbjct: 2 ENTDVVSGLHNF------LSKPSAKDFIKSIKSFIVSILN-----TAPDPEKDCDAVQDF 50
Query: 83 KVFIYDKLLTNEAFRDLSDAQIKNAKEGIEKLVMGKLYYKCFSPCLVNEKRSSDATHEQD 142
+ + + SD ++ NA +G+EK VM KL+ + F A++ +D
Sbjct: 51 FYKMESAFRAHPLWSGCSDDELDNAGDGLEKYVMTKLFPRVF------------ASNTED 98
Query: 143 LLDDAKLRDKI-LEFRFLGPEHLDIIPDLINGKLHSFIALSAKELAKINQYRSPRDKMVC 201
++ D KL KI L +F+ PE+LDI P N + L+ KEL KIN Y +PRDK++C
Sbjct: 99 VISDEKLFQKISLVQQFISPENLDIQPTFQN---QTSWLLAQKELQKINMYNAPRDKLMC 155
Query: 202 VLNSCKVLFGLLKH----NNKLNGGADHFVPLLIFTLLKSDVPHLISNVRYIERFRFPSF 257
+L CKV+ LL + +N+ GAD F+P+LI+ +K++ P SN+ YI+R+R S
Sbjct: 156 ILRCCKVINNLLLNASIASNQNEPGADQFLPVLIYVTIKANPPQFHSNLLYIQRYRRQSK 215
Query: 258 LMGENAYYLSTLQGAVNFXXXXXXXXXXXXETDKDFNKK 296
L+GE Y + + A +F E D + K
Sbjct: 216 LVGEAGYLFTNILSAESFISNIDAKSLSMDEADFETKMK 254
>At3g19770 [U] KOG2319 Vacuolar assembly/sorting protein VPS9
Length = 472
Score = 123 bits (309), Expect = 5e-28
Identities = 82/242 (33%), Positives = 130/242 (52%), Gaps = 29/242 (11%)
Query: 100 SDAQIKNAKEGIEKLVMGKLYYKCFSPCLVNEKRSSDATHEQDLLDDAKLRDKI-LEFRF 158
S+ ++ +A +G+EK VM KL+ + F A++ ++++ D KL K+ L +F
Sbjct: 23 SEEELDSAGDGLEKYVMTKLFTRVF------------ASNTEEVIADEKLFQKMSLVQQF 70
Query: 159 LGPEHLDIIPDLINGKLHSFIALSAKELAKINQYRSPRDKMVCVLNSCKVLFGLLKH--- 215
+ PE+LDI P N S L+ KEL KIN Y++PRDK+VC+LN CKV+ LL +
Sbjct: 71 ISPENLDIQPTFQN---ESSWLLAQKELQKINMYKAPRDKLVCILNCCKVINNLLLNASI 127
Query: 216 -NNKLNGGADHFVPLLIFTLLKSDVPHLISNVRYIERFRFPSFLMGENAYYLSTLQGAVN 274
+N+ GAD F+P+LI+ +K++ P L SN+ YI+R+R S L+GE AY+ + + A +
Sbjct: 128 ASNENAPGADEFLPVLIYVTIKANPPQLHSNLLYIQRYRRESKLVGEAAYFFTNILSAES 187
Query: 275 FXXXXXXXXXXXXETDKDFNKKYSQNQEEIKDLKKQELLN-------PKDSSTKFPHRTV 327
F E +F K + I L Q P+D ST +++
Sbjct: 188 FISNIDAKSISLDEA--EFEKNMESARARISGLDSQTYQTGHGSAPPPRDESTLQKTQSL 245
Query: 328 SP 329
+P
Sbjct: 246 NP 247
>Hs20538500 [U] KOG2319 Vacuolar assembly/sorting protein VPS9
Length = 1292
Score = 92.4 bits (228), Expect = 1e-18
Identities = 65/220 (29%), Positives = 114/220 (51%), Gaps = 18/220 (8%)
Query: 60 IRNFVSQRENWTTSEQEKL-INDFKVFIYDKLLTNEAFRDLSDAQIKNAKEGIEKLVMGK 118
IR F+ + T ++ + + DF F+Y + + +++ S+ Q+++A+ IE+ VM +
Sbjct: 1079 IREFIQDFQKLTAADDKTAQVEDFLQFLYGAMAQDVIWQNASEEQLQDAQLAIERSVMNR 1138
Query: 119 LYYKCFSPCLVNEKRSSDATHEQDLLDDAKLRDKILEF-RFLGPEHLDI-IPDLINGKLH 176
++ F P + D+L D L + I + + H + IP++ +
Sbjct: 1139 IFKLAFYP-----------NQDGDILRDQVLHEHIQRLSKVVTANHRALQIPEVYLREAP 1187
Query: 177 SFIALSAKELAKINQYRSPRDKMVCVLNSCKVLFGLLKHNNKLN-GGADHFVPLLIFTLL 235
A S E+ I+ Y++PRDK+ C+L C + LL N+ + GAD FVP+L+F L+
Sbjct: 1188 WPSAQS--EIRTISAYKTPRDKVQCILRMCSTIMNLLSLANEDSVPGADDFVPVLVFVLI 1245
Query: 236 KSDVPHLISNVRYIERFRFPSFLMGENAYYLSTLQGAVNF 275
K++ P L+S V+YI F + S L GE +Y+ AV F
Sbjct: 1246 KANPPCLLSTVQYISSF-YASCLSGEESYWWMQFTAAVEF 1284
>Hs7657496_3 [U] KOG2319 Vacuolar assembly/sorting protein VPS9
Length = 379
Score = 90.1 bits (222), Expect = 6e-18
Identities = 67/258 (25%), Positives = 119/258 (45%), Gaps = 17/258 (6%)
Query: 36 DFQAFLKIMRDPKADPIVKHTKSFIRNFVSQRENWTTSEQEKLINDFKVFIYDKLLTNEA 95
+F FLK + I K TK F+ +R+ + EQ + DF + +++ T
Sbjct: 29 EFIEFLKTFHKTGQE-IYKQTKLFLEGMHYKRD-LSIEEQSECAQDFYHNVAERMQTRGK 86
Query: 96 FRDLSDAQIKNAKEGIEKLVMGKLYYKCFSPCLVNEKRSSDATHEQDLLDDAKLRDKILE 155
+ +++ + IEK +M +LY F P ++++ D ++ +I
Sbjct: 87 ---VPPERVEKIMDQIEKYIMTRLYKYVFCPETTDDEKK-----------DLAIQKRIRA 132
Query: 156 FRFLGPEHLDIIPDLINGKLHSFIALSAKELAKINQYRSPRDKMVCVLNSCKVLFGLLKH 215
R++ P+ L + + ++ + + ++ +++ R PRDK+ C+ K +F +K
Sbjct: 133 LRWVTPQMLCVPVNEDIPEVSDMVVKAITDIIEMDSKRVPRDKLACITKCSKHIFNAIKI 192
Query: 216 NNKLNGGADHFVPLLIFTLLKSDVPHLISNVRYIERFRFPSFLM-GENAYYLSTLQGAVN 274
AD F+P LI+ +LK + P L SN++YI RF PS LM GE+ YY + L AV
Sbjct: 193 TKNEPASADDFLPTLIYIVLKGNPPRLQSNIQYITRFCNPSRLMTGEDGYYFTNLCCAVA 252
Query: 275 FXXXXXXXXXXXXETDKD 292
F + D D
Sbjct: 253 FIEKLDAQSLNLSQEDFD 270
>7292054_2 [U] KOG2319 Vacuolar assembly/sorting protein VPS9
Length = 521
Score = 90.1 bits (222), Expect = 6e-18
Identities = 58/204 (28%), Positives = 101/204 (49%), Gaps = 12/204 (5%)
Query: 73 SEQEKLINDFKVFIYDKLLTNEAFRDLSDAQIKNAKEGIEKLVMGKLYYKCFSPCLVNEK 132
+E L+ + + D + + +F ++ +A + EK+VM + + FSP ++
Sbjct: 1 NELSDLVQNAYTKVSDIVHNDPSFEIATNEDRDSAIDFFEKVVMTQNHKFLFSPYFTTDE 60
Query: 133 RSSDATHEQDLLDDAKLRDKILEFRFLGPEHLDIIPDLINGKLHSFIALSAKELAKINQY 192
S D K++ +I + ++ +HLD D +N + + + EL I+ Y
Sbjct: 61 DS-----------DVKVQKRIRQLSWITAKHLDCSIDEVNSEARDLVYNAISELVGIDSY 109
Query: 193 RSPRDKMVCVLNSCKVLFGLLKHNNKLNGGADHFVPLLIFTLLKSDVPHLISNVRYIERF 252
SP++K+ C C+ +F LLK AD F+P LIF +LK++ L SN+ ++ RF
Sbjct: 110 YSPQEKLQCTWRCCRHIFELLKRATGGPASADDFLPALIFVVLKANPVRLHSNINFVTRF 169
Query: 253 RFPSFLM-GENAYYLSTLQGAVNF 275
S LM GE+ YY + L A+ F
Sbjct: 170 TNASRLMSGESGYYFTNLCSAIAF 193
>CE26367 [U] KOG2319 Vacuolar assembly/sorting protein VPS9
Length = 1109
Score = 72.0 bits (175), Expect = 2e-12
Identities = 55/205 (26%), Positives = 101/205 (48%), Gaps = 16/205 (7%)
Query: 74 EQEKLINDFKVFIYDKLLTNEAFRDLSDAQIKNAKEGIEKLVMGKLYYKCFSPCLVNEKR 133
E+ + + + F+ D+L+ N + +D + A IE+ V+ +Y F P
Sbjct: 913 ERAEFLKNLLTFLRDRLMQNVDWNFATDTMMSRAMTTIERYVIFAVYDNAFYP------- 965
Query: 134 SSDATHEQDLLDDAKLRDKILEFRFLGPEHLDI--IPDLINGKLHSFIALSAKELAKINQ 191
+ DA H +D L LR I + + D IP+ ++G+ A + EL+ ++
Sbjct: 966 NRDADHHRDKL----LRGTIAKVSDVVTPVNDFLKIPEHLHGEAPWPSAQA--ELSMLDI 1019
Query: 192 YRSPRDKMVCVLNSCKVLFGLLKHNNK-LNGGADHFVPLLIFTLLKSDVPHLISNVRYIE 250
Y + +DK+ CV+ C V+ L+ ++K AD P+L+F ++K++ L+SNV+++E
Sbjct: 1020 YVTAQDKLNCVVRCCDVINNLVALSSKNAVASADDLTPVLVFVIIKANPRALLSNVQFVE 1079
Query: 251 RFRFPSFLMGENAYYLSTLQGAVNF 275
F G +AYY + AV +
Sbjct: 1080 TFAGDRIESGRDAYYWVNFKSAVEY 1104
>7292625_2 [U] KOG2319 Vacuolar assembly/sorting protein VPS9
Length = 317
Score = 62.8 bits (151), Expect = 1e-09
Identities = 49/207 (23%), Positives = 101/207 (48%), Gaps = 20/207 (9%)
Query: 72 TSEQEKLINDFKVFIYDKLLTNEAFRDLSDAQIKNAKEGIEKLVMGKLYYKCFSPCLVNE 131
+ E+ +L +F + +L ++ +D + Q+ A+ IE++++ ++Y + P
Sbjct: 120 SDERVELTEEFVESLLQELRSSADLQD--EWQVDAARVAIERMLLEQMYEQVMFP----- 172
Query: 132 KRSSDATHEQDLLDDAKLRDKILEF-RFLGPEH--LDIIPDLINGKLHSFIALSAKELAK 188
+ D+ D L I + RF+ P H L I + + +F + ++L
Sbjct: 173 ------NEDADVSRDEVLSAHIGKLQRFVHPAHPALCIAQEYLGEAPWTF---AQQQLCH 223
Query: 189 INQYRSPRDKMVCVLNSCKVLFGLLKHNNKLNGGADHFVPLLIFTLLKSDVPHLISNVRY 248
+ Y++PR+K+ C++N + LL+ ++ AD +P+LI+ ++ ++ P+L+S V Y
Sbjct: 224 MAAYKTPREKLQCIINCISSIMSLLRMSSGRVPAADDLLPVLIYVVIMANPPYLLSTVEY 283
Query: 249 IERFRFPSFLMGENAYYLSTLQGAVNF 275
I F L GE+ +Y + V F
Sbjct: 284 ISCF-LGKKLEGEDEFYWTLFGSVVKF 309
>Hs14149803 [U] KOG2319 Vacuolar assembly/sorting protein VPS9
Length = 1050
Score = 59.7 bits (143), Expect = 8e-09
Identities = 56/233 (24%), Positives = 107/233 (45%), Gaps = 29/233 (12%)
Query: 54 KHTKSFIRNFVSQRENWTTSEQEKLIN--DFKVFIYDKLLTNEAFRDL-------SDAQI 104
+H++ F RN S + E++ L + D +Y K L + RD +AQ+
Sbjct: 147 RHSERFDRNIASFHRTFRECERKSLRHHIDSANALYTKCL-QQLLRDSHLKMLAKQEAQM 205
Query: 105 KNAKEGIEKLVMGKLYYKCFSPCLVNEKRSSDATHEQDLLDDAKLRDKILEFRFLGPEHL 164
K+ +E V ++Y F V +S+ DA + L + +
Sbjct: 206 NLMKQAVEIYVHHEIYNLIFK--YVGTMEASE---------DAAFNKITRSLQDLQQKDI 254
Query: 165 DIIPDLINGKLHSF-IALSAKELAKINQYRSPRDKMVCVLNSCKVLFGLLKHNNKLNGG- 222
+ P+ SF I + +ELA++N+ SP+ K+VC+ +++ L
Sbjct: 255 GVKPEF------SFNIPRAKRELAQLNKCTSPQQKLVCLRKVVQLITQSPSQRVNLETMC 308
Query: 223 ADHFVPLLIFTLLKSDVPHLISNVRYIERFRFPSFLMGENAYYLSTLQGAVNF 275
AD + +L++ L+K+++P+ ++N+ YI+ FRF S E Y L++ + A+ +
Sbjct: 309 ADDLLSVLLYLLVKTEIPNWMANLSYIKNFRFSSLAKDELGYCLTSFEAAIEY 361
>Hs18466802 [U] KOG2320 RAS effector RIN1 (contains VPS domain)
Length = 895
Score = 59.3 bits (142), Expect = 1e-08
Identities = 34/130 (26%), Positives = 69/130 (52%), Gaps = 9/130 (6%)
Query: 148 KLRDKILEFRFLGPEHLDII---PDLINGKLHSFIALSAKELAKINQYRSPRDKMVCVLN 204
+L++ + R P+ L + PD ++ + + K + Y SP K++ +L
Sbjct: 623 QLKENLQLVRQRNPQELGVFAPTPDFVDVE-----KIKVKFMTMQKMY-SPEKKVMLLLR 676
Query: 205 SCKVLFGLLKHNNKLNGGADHFVPLLIFTLLKSDVPHLISNVRYIERFRFPSFLMGENAY 264
CK+++ ++++N+ GAD F+P+L + + + D+ L + + Y+ PS L GE Y
Sbjct: 677 VCKLIYTVMENNSGRMYGADDFLPVLTYVIAQCDMLELDTEIEYMMELLDPSLLHGEGGY 736
Query: 265 YLSTLQGAVN 274
YL++ GA++
Sbjct: 737 YLTSAYGALS 746
>HsM13376238 [U] KOG2320 RAS effector RIN1 (contains VPS domain)
Length = 497
Score = 57.4 bits (137), Expect = 4e-08
Identities = 27/91 (29%), Positives = 54/91 (58%), Gaps = 1/91 (1%)
Query: 184 KELAKINQYRSPRDKMVCVLNSCKVLFGLLKHNNKLNG-GADHFVPLLIFTLLKSDVPHL 242
++ +++ SP K+ +L +CK+++ + N GAD F+P+L++ L +S++ +
Sbjct: 257 QKFTSMHKAYSPEKKISILLKTCKLIYDSMALGNPGKPYGADDFLPVLMYVLARSNLTEM 316
Query: 243 ISNVRYIERFRFPSFLMGENAYYLSTLQGAV 273
+ NV Y+ P+ +GE +YYL+T GA+
Sbjct: 317 LLNVEYMMELMDPALQLGEGSYYLTTTYGAL 347
>Hs4759040 [U] KOG2320 RAS effector RIN1 (contains VPS domain)
Length = 783
Score = 57.4 bits (137), Expect = 4e-08
Identities = 29/90 (32%), Positives = 49/90 (54%)
Query: 184 KELAKINQYRSPRDKMVCVLNSCKVLFGLLKHNNKLNGGADHFVPLLIFTLLKSDVPHLI 243
++L ++ + SP ++ +L +CK+L+ L+ GAD F+PLL L D+P L+
Sbjct: 497 QKLLQLVRTYSPSAQVKRLLQACKLLYMALRTQEGEGSGADGFLPLLSLVLAHCDLPELL 556
Query: 244 SNVRYIERFRFPSFLMGENAYYLSTLQGAV 273
Y+ PS L GE YYL++L ++
Sbjct: 557 LEAEYMSELLEPSLLTGEGGYYLTSLSASL 586
>Hs21314732 [U] KOG2320 RAS effector RIN1 (contains VPS domain)
Length = 497
Score = 57.4 bits (137), Expect = 4e-08
Identities = 27/91 (29%), Positives = 54/91 (58%), Gaps = 1/91 (1%)
Query: 184 KELAKINQYRSPRDKMVCVLNSCKVLFGLLKHNNKLNG-GADHFVPLLIFTLLKSDVPHL 242
++ +++ SP K+ +L +CK+++ + N GAD F+P+L++ L +S++ +
Sbjct: 257 QKFTSMHKAYSPEKKISILLKTCKLIYDSMALGNPGKPYGADDFLPVLMYVLARSNLTEM 316
Query: 243 ISNVRYIERFRFPSFLMGENAYYLSTLQGAV 273
+ NV Y+ P+ +GE +YYL+T GA+
Sbjct: 317 LLNVEYMMELMDPALQLGEGSYYLTTTYGAL 347
>CE26468 [U] KOG2319 Vacuolar assembly/sorting protein VPS9
Length = 94
Score = 53.1 bits (126), Expect = 8e-07
Identities = 27/85 (31%), Positives = 48/85 (55%), Gaps = 1/85 (1%)
Query: 192 YRSPRDKMVCVLNSCKVLFGLLKHNNK-LNGGADHFVPLLIFTLLKSDVPHLISNVRYIE 250
Y + +DK+ CV+ C V+ L+ ++K AD P+L+F ++K++ L+SNV+++E
Sbjct: 5 YVTAQDKLNCVVRCCDVINNLVALSSKNAVASADDLTPVLVFVIIKANPRALLSNVQFVE 64
Query: 251 RFRFPSFLMGENAYYLSTLQGAVNF 275
F G +AYY + AV +
Sbjct: 65 TFAGDRIESGRDAYYWVNFKSAVEY 89
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.318 0.136 0.391
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,086,283
Number of Sequences: 60738
Number of extensions: 1115250
Number of successful extensions: 3218
Number of sequences better than 1.0e-05: 15
Number of HSP's better than 0.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 3183
Number of HSP's gapped (non-prelim): 18
length of query: 437
length of database: 30,389,216
effective HSP length: 109
effective length of query: 328
effective length of database: 23,768,774
effective search space: 7796157872
effective search space used: 7796157872
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)