ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIV2553 good L KOG2841 Replication, recombination and repair Structure-specific endonuclease ERCC1-XPF, ERCC1 component
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIV2553 872050 871352 -233
(233 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YML095c [L] KOG2841 Structure-specific endonuclease ERCC1-XPF ER... 150 1e-36
SPBC4F6.15c [L] KOG2841 Structure-specific endonuclease ERCC1-XP... 74 1e-13
Hs4503599 [L] KOG2841 Structure-specific endonuclease ERCC1-XPF ... 74 1e-13
CE09342 [L] KOG2841 Structure-specific endonuclease ERCC1-XPF ER... 66 4e-11
At3g05210 [L] KOG2841 Structure-specific endonuclease ERCC1-XPF ... 66 4e-11
7303131 [L] KOG2841 Structure-specific endonuclease ERCC1-XPF ER... 65 8e-11
ECU10g1330 [L] KOG2841 Structure-specific endonuclease ERCC1-XPF... 62 5e-10
>YML095c [L] KOG2841 Structure-specific endonuclease ERCC1-XPF ERCC1
component
Length = 210
Score = 150 bits (379), Expect = 1e-36
Identities = 91/232 (39%), Positives = 124/232 (53%), Gaps = 30/232 (12%)
Query: 4 DTTSFESILANVRKRRAEFNXXXXXXXXXXXXXXXXXXAPELTRKQNEHPNLRDASINSQ 63
D TSFESILA V K R E + T Q+ DAS Q
Sbjct: 5 DPTSFESILAGVAKLRKE------------------KSGADTTGSQSLE---IDASKLQQ 43
Query: 64 QRSVTTSK-PSGPVINSFNQQ--HDTSPGNAPVIHNQKKAVQEXXXXXXXXXXXXXXXXX 120
Q T+ + S VIN+FNQQ + + A +N+K+ +
Sbjct: 44 QEPQTSRRINSNQVINAFNQQKPEEWTDSKATDDYNRKRPFR------STRPGKTVLVNT 97
Query: 121 XQTGNPLLKSLVNVNWRYVKSTPTTQVHYDYQIRGRNVIFLSLKYHKLHPEYIGKKLLPF 180
Q NPLL L + NWRYV ST ++YDY +RGR+V+FL+L YHKL+ +YI +++ P
Sbjct: 98 TQKENPLLNHLKSTNWRYVSSTGINMIYYDYLVRGRSVLFLTLTYHKLYVDYISRRMQPL 157
Query: 181 KRTEGNVLLCVVDVENSEDILRELNKVCMFQGFTILLAFTFEQAGKYLTFMN 232
R E N+L+ +VD NSED L ++ K+CMF GFT+LLAF FEQA KY+ ++N
Sbjct: 158 SRNENNILIFIVDDNNSEDTLNDITKLCMFNGFTLLLAFNFEQAAKYIEYLN 209
>SPBC4F6.15c [L] KOG2841 Structure-specific endonuclease ERCC1-XPF ERCC1
component
Length = 252
Score = 74.3 bits (181), Expect = 1e-13
Identities = 43/110 (39%), Positives = 65/110 (59%), Gaps = 10/110 (9%)
Query: 122 QTGNPLLKSLVNVNWRYVKSTPTTQVHYDYQIRGRNV--IFLSLKYHKLHPEYIGKKLLP 179
Q GNPLL + NV W Y P D+ + G + +FLSLKYH LHPEYI ++
Sbjct: 49 QKGNPLLPHVRNVPWEYTDIVP------DF-VMGTGICSLFLSLKYHHLHPEYIYSRISK 101
Query: 180 FKRTEG-NVLLCVVDVENSEDILRELNKVCMFQGFTILLAFTFEQAGKYL 228
++ +LL +VDVEN + ++EL K + +T++LA++ E+A +YL
Sbjct: 102 LGKSYNLRILLILVDVENHQASIQELVKTSIVNQYTLILAWSSEEAARYL 151
>Hs4503599 [L] KOG2841 Structure-specific endonuclease ERCC1-XPF ERCC1
component
Length = 297
Score = 74.3 bits (181), Expect = 1e-13
Identities = 44/109 (40%), Positives = 65/109 (59%), Gaps = 8/109 (7%)
Query: 122 QTGNPLLKSLVNVNWRYVKSTPTTQVHYDYQI-RGRNVIFLSLKYHKLHPEYIGKKLLPF 180
Q GNP+LK + NV W + P DY + + +FLSL+YH LHP+YI +L
Sbjct: 107 QRGNPVLKFVRNVPWEFGDVIP------DYVLGQSTCALFLSLRYHNLHPDYIHGRLQSL 160
Query: 181 -KRTEGNVLLCVVDVENSEDILRELNKVCMFQGFTILLAFTFEQAGKYL 228
K VLL VDV++ + L+EL K+C+ T++LA++ E+AG+YL
Sbjct: 161 GKNFALRVLLVQVDVKDPQQALKELAKMCILADCTLILAWSPEEAGRYL 209
>CE09342 [L] KOG2841 Structure-specific endonuclease ERCC1-XPF ERCC1
component
Length = 296
Score = 66.2 bits (160), Expect = 4e-11
Identities = 36/109 (33%), Positives = 59/109 (54%), Gaps = 7/109 (6%)
Query: 122 QTGNPLLKSLVNVNWRYVKSTPTTQVHYDYQIRGRNVIFLSLKYHKLHPEYIGKKLL--P 179
Q GNP+LK + NV + + P + + V++LS KYHK HPEY+ ++
Sbjct: 92 QEGNPVLKYVRNVRYEWGDIGPDFECGPTF-----GVVYLSFKYHKQHPEYVYTRINGNA 146
Query: 180 FKRTEGNVLLCVVDVENSEDILRELNKVCMFQGFTILLAFTFEQAGKYL 228
R VLL ++E +LRELN +C + +T ++ +T E+A +Y+
Sbjct: 147 ENRYRNKVLLGYCNMEEPRHVLRELNMICFREAWTFVVVYTVEEAAEYI 195
>At3g05210 [L] KOG2841 Structure-specific endonuclease ERCC1-XPF ERCC1
component
Length = 410
Score = 66.2 bits (160), Expect = 4e-11
Identities = 48/168 (28%), Positives = 82/168 (48%), Gaps = 16/168 (9%)
Query: 66 SVTTSKPSGP--VINSFNQQHDTSPGNAPVIHNQKKAVQEXXXXXXXXXXXXXXXXXXQT 123
+ ++S+PSG V +S +Q H T ++ + Q
Sbjct: 78 AASSSQPSGASQVPHSSSQTHQTDGASS----SSTPVATGSVPSNTTQNRNAILVSHRQK 133
Query: 124 GNPLLKSLVNVNWRYVKSTPTTQVHYDYQIRGRN--VIFLSLKYHKLHPEYIGKKLLPFK 181
GNPLLK + NV W + P DY + G+N ++LSL+YH LHP+Y+ ++ +
Sbjct: 134 GNPLLKHIRNVKWVFSDIIP------DY-VLGQNSCALYLSLRYHLLHPDYLYFRIRELQ 186
Query: 182 RT-EGNVLLCVVDVENSEDILRELNKVCMFQGFTILLAFTFEQAGKYL 228
+ + +V+LC VDVE++ L E+ K + T+L A++ + +YL
Sbjct: 187 KNFKLSVVLCHVDVEDTVKPLLEVTKTALLHDCTLLCAWSMTECARYL 234
>7303131 [L] KOG2841 Structure-specific endonuclease ERCC1-XPF ERCC1
component
Length = 259
Score = 65.1 bits (157), Expect = 8e-11
Identities = 40/109 (36%), Positives = 62/109 (56%), Gaps = 7/109 (6%)
Query: 122 QTGNPLLKSLVNVNWRYVKSTPTTQVHYDYQI-RGRNVIFLSLKYHKLHPEYIGKKLLPF 180
Q GNP+LKS++NV + + DY + R V++LSLKYH L+P+YI ++L
Sbjct: 69 QRGNPILKSILNVPLEF-----RDDIVPDYVVGRTSCVLYLSLKYHNLNPDYICQRLKAL 123
Query: 181 -KRTEGNVLLCVVDVENSEDILRELNKVCMFQGFTILLAFTFEQAGKYL 228
K E VLL VD + L+ L ++ + T++LA+ E+AGK +
Sbjct: 124 GKMYELRVLLVQVDTPEPNNALKSLTRISLLADLTMMLAWNAEEAGKII 172
>ECU10g1330 [L] KOG2841 Structure-specific endonuclease ERCC1-XPF ERCC1
component
Length = 187
Score = 62.4 bits (150), Expect = 5e-10
Identities = 40/113 (35%), Positives = 60/113 (52%), Gaps = 11/113 (9%)
Query: 122 QTGNPLLKSLVNVNWRYVKS-TPTTQVHYDYQIRGR-NVIFLSLKYHKLHPEYIGKKLLP 179
Q GN +L L N +W Y S TP DY+I ++FLSL++H PEYI K++
Sbjct: 8 QKGNSVLGYLSNTSWHYDNSITP------DYEINSSVALLFLSLRFHSCKPEYIHKRISK 61
Query: 180 FKRTEGNVLLCVVDVENSEDILRELNKVCMFQGFTILLAFTFEQAGKYLTFMN 232
K + VLL VD+ N ++REL + T++L F+ E+ +Y+ N
Sbjct: 62 LKPYKTRVLLVHVDIPNYSKMIRELFET---TSLTMVLGFSVEECSRYIQGFN 111
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.317 0.133 0.383
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,251,893
Number of Sequences: 60738
Number of extensions: 459007
Number of successful extensions: 1005
Number of sequences better than 1.0e-05: 7
Number of HSP's better than 0.0 without gapping: 1
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 991
Number of HSP's gapped (non-prelim): 8
length of query: 233
length of database: 30,389,216
effective HSP length: 103
effective length of query: 130
effective length of database: 24,133,202
effective search space: 3137316260
effective search space used: 3137316260
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)