ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIV2621 check: MH D KOG0600 Cell cycle control, cell division, chromosome partitioning Cdc2-related protein kinase
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIV2621 892955 894889 645
(645 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YPR161c [D] KOG0600 Cdc2-related protein kinase 608 e-174
SPBC32H8.10 [D] KOG0600 Cdc2-related protein kinase 234 3e-61
7291442 [D] KOG0669 Cyclin T-dependent kinase CDK9 226 8e-59
At5g10270 [D] KOG0600 Cdc2-related protein kinase 225 1e-58
At5g64960 [D] KOG0600 Cdc2-related protein kinase 221 3e-57
SPAC2F3.15 [D] KOG0600 Cdc2-related protein kinase 217 4e-56
CE26422 [D] KOG0600 Cdc2-related protein kinase 217 4e-56
Hs4502747 [D] KOG0669 Cyclin T-dependent kinase CDK9 216 9e-56
At1g67580 [R] KOG0663 Protein kinase PITSLRE and related kinases 214 2e-55
Hs16357498 [R] KOG0663 Protein kinase PITSLRE and related kinases 212 2e-54
Hs16357496 [R] KOG0663 Protein kinase PITSLRE and related kinases 212 2e-54
Hs16357486 [R] KOG0663 Protein kinase PITSLRE and related kinases 212 2e-54
Hs16357484 [R] KOG0663 Protein kinase PITSLRE and related kinases 212 2e-54
Hs16357482 [R] KOG0663 Protein kinase PITSLRE and related kinases 212 2e-54
Hs16357480 [R] KOG0663 Protein kinase PITSLRE and related kinases 212 2e-54
Hs16332372 [R] KOG0663 Protein kinase PITSLRE and related kinases 212 2e-54
Hs16332370 [R] KOG0663 Protein kinase PITSLRE and related kinases 212 2e-54
Hs16332368 [R] KOG0663 Protein kinase PITSLRE and related kinases 212 2e-54
Hs16332366 [R] KOG0663 Protein kinase PITSLRE and related kinases 212 2e-54
Hs16332364 [R] KOG0663 Protein kinase PITSLRE and related kinases 212 2e-54
Hs16332362 [R] KOG0663 Protein kinase PITSLRE and related kinases 212 2e-54
Hs16332360 [R] KOG0663 Protein kinase PITSLRE and related kinases 212 2e-54
Hs16332358 [R] KOG0663 Protein kinase PITSLRE and related kinases 212 2e-54
Hs10835055 [R] KOG0663 Protein kinase PITSLRE and related kinases 212 2e-54
Hs16357494 [R] KOG0663 Protein kinase PITSLRE and related kinases 211 3e-54
Hs16357492 [R] KOG0663 Protein kinase PITSLRE and related kinases 211 3e-54
CE23826 [D] KOG0669 Cyclin T-dependent kinase CDK9 211 3e-54
7296451 [D] KOG0600 Cdc2-related protein kinase 210 5e-54
YKL139w [D] KOG0600 Cdc2-related protein kinase 209 1e-53
CE18824 [D] KOG0669 Cyclin T-dependent kinase CDK9 209 1e-53
Hs7706549 [D] KOG0600 Cdc2-related protein kinase 207 5e-53
CE01761 [R] KOG0663 Protein kinase PITSLRE and related kinases 202 1e-51
Hs4557439 [R] KOG0594 Protein kinase PCTAIRE and related kinases 200 6e-51
7296346 [R] KOG0663 Protein kinase PITSLRE and related kinases 200 6e-51
Hs14110390 [D] KOG0600 Cdc2-related protein kinase 199 8e-51
Hs14110387 [D] KOG0600 Cdc2-related protein kinase 199 1e-50
Hs4502731 [R] KOG0663 Protein kinase PITSLRE and related kinases 198 2e-50
At3g48750 [R] KOG0594 Protein kinase PCTAIRE and related kinases 198 2e-50
At1g74330 [D] KOG0600 Cdc2-related protein kinase 196 9e-50
Hs4502709 [R] KOG0594 Protein kinase PCTAIRE and related kinases 195 2e-49
At5g63370 [R] KOG0663 Protein kinase PITSLRE and related kinases 195 2e-49
Hs16936528 [R] KOG0594 Protein kinase PCTAIRE and related kinases 195 2e-49
Hs16950647 [R] KOG0663 Protein kinase PITSLRE and related kinases 192 1e-48
At1g18670 [D] KOG0600 Cdc2-related protein kinase 192 1e-48
At1g09600 [D] KOG0600 Cdc2-related protein kinase 191 4e-48
SPBC18H10.15 [R] KOG0663 Protein kinase PITSLRE and related kinases 187 3e-47
At1g73690 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymera... 187 3e-47
SPBC19F8.07 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polyme... 187 4e-47
CE03811 [R] KOG0663 Protein kinase PITSLRE and related kinases 187 4e-47
At5g50860 [D] KOG0600 Cdc2-related protein kinase 187 4e-47
At1g54610 [D] KOG0600 Cdc2-related protein kinase 186 1e-46
7300650 [R] KOG0594 Protein kinase PCTAIRE and related kinases 186 1e-46
CE00315 [R] KOG0594 Protein kinase PCTAIRE and related kinases 185 2e-46
At1g71530 [D] KOG0600 Cdc2-related protein kinase 185 2e-46
YBR160w [R] KOG0594 Protein kinase PCTAIRE and related kinases 184 3e-46
At1g53050 [D] KOG0600 Cdc2-related protein kinase 184 5e-46
At5g39420 [D] KOG0600 Cdc2-related protein kinase 183 8e-46
At1g33770 [D] KOG0600 Cdc2-related protein kinase 183 8e-46
At4g10010 [D] KOG0600 Cdc2-related protein kinase 182 1e-45
At1g18040 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymera... 182 1e-45
CE18009 [R] KOG0594 Protein kinase PCTAIRE and related kinases 182 2e-45
At1g66750 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymera... 179 1e-44
7297680 [R] KOG0594 Protein kinase PCTAIRE and related kinases 179 2e-44
At5g63610 [K] KOG0666 Cyclin C-dependent kinase CDK8 177 4e-44
7303804 [R] KOG0663 Protein kinase PITSLRE and related kinases 176 1e-43
At5g44290 [D] KOG0600 Cdc2-related protein kinase 175 2e-43
SPBC11B10.09 [R] KOG0594 Protein kinase PCTAIRE and related kinases 174 3e-43
YDL108w [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase... 174 4e-43
7303051 [UT] KOG0662 Cyclin-dependent kinase CDK5 174 4e-43
Hs7705551 [T] KOG0661 MAPK related serine/threonine protein kinase 174 5e-43
Hs7662388 [T] KOG0661 MAPK related serine/threonine protein kinase 174 5e-43
Hs4505649 [R] KOG0594 Protein kinase PCTAIRE and related kinases 172 1e-42
At4g22940 [D] KOG0600 Cdc2-related protein kinase 172 1e-42
At1g03740 [D] KOG0600 Cdc2-related protein kinase 172 1e-42
Hs4502743 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymera... 172 2e-42
Hs5453860 [R] KOG0594 Protein kinase PCTAIRE and related kinases 170 5e-42
Hs15011928 [R] KOG0594 Protein kinase PCTAIRE and related kinases 170 5e-42
YPL031c [R] KOG0594 Protein kinase PCTAIRE and related kinases 169 2e-41
At1g57700 [D] KOG0600 Cdc2-related protein kinase 169 2e-41
Hs4502741 [R] KOG0594 Protein kinase PCTAIRE and related kinases 168 3e-41
Hs11496279 [T] KOG0661 MAPK related serine/threonine protein kinase 168 3e-41
SPCC16C4.11 [R] KOG0594 Protein kinase PCTAIRE and related kinases 167 4e-41
Hs4826675 [UT] KOG0662 Cyclin-dependent kinase CDK5 167 4e-41
7290565 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase... 165 2e-40
At2g38620 [R] KOG0594 Protein kinase PCTAIRE and related kinases 162 2e-39
7297578 [T] KOG0661 MAPK related serine/threonine protein kinase 162 2e-39
Hs16160923 [R] KOG0594 Protein kinase PCTAIRE and related kinases 161 3e-39
CE21213 [UT] KOG0662 Cyclin-dependent kinase CDK5 160 6e-39
At3g05050 [D] KOG0600 Cdc2-related protein kinase 160 6e-39
CE12408 [T] KOG0661 MAPK related serine/threonine protein kinase 160 7e-39
At1g76540 [R] KOG0594 Protein kinase PCTAIRE and related kinases 159 1e-38
7292375 [R] KOG0594 Protein kinase PCTAIRE and related kinases 159 1e-38
ECU02g1450 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymer... 158 3e-38
ECU08g1920 [R] KOG0594 Protein kinase PCTAIRE and related kinases 156 8e-38
At1g20930 [R] KOG0594 Protein kinase PCTAIRE and related kinases 155 2e-37
Hs4506785 [T] KOG0660 Mitogen-activated protein kinase 154 4e-37
At3g54180 [R] KOG0594 Protein kinase PCTAIRE and related kinases 153 7e-37
CE29612 [R] KOG0594 Protein kinase PCTAIRE and related kinases 152 1e-36
Hs6912584 [R] KOG0594 Protein kinase PCTAIRE and related kinases 152 2e-36
Hs21040235 [R] KOG0594 Protein kinase PCTAIRE and related kinases 151 3e-36
Hs4506085 [T] KOG0660 Mitogen-activated protein kinase 150 8e-36
Hs4502745 [K] KOG0666 Cyclin C-dependent kinase CDK8 149 1e-35
CE29073 [R] KOG0594 Protein kinase PCTAIRE and related kinases 149 1e-35
CE06779 [R] KOG0594 Protein kinase PCTAIRE and related kinases 149 1e-35
At5g45430 [T] KOG0661 MAPK related serine/threonine protein kinase 149 1e-35
7294866 [K] KOG0666 Cyclin C-dependent kinase CDK8 149 1e-35
At4g13020 [T] KOG0661 MAPK related serine/threonine protein kinase 149 2e-35
Hs4507281 [R] KOG0593 Predicted protein kinase KKIAMRE 148 3e-35
7302908 [R] KOG0594 Protein kinase PCTAIRE and related kinases 146 1e-34
Hs4502735 [R] KOG0594 Protein kinase PCTAIRE and related kinases 145 1e-34
YBL016w [T] KOG0660 Mitogen-activated protein kinase 144 4e-34
Hs20551615 [K] KOG0666 Cyclin C-dependent kinase CDK8 144 4e-34
Hs4505569 [R] KOG0593 Predicted protein kinase KKIAMRE 144 5e-34
7291043 [T] KOG0660 Mitogen-activated protein kinase 143 7e-34
ECU11g0960 [D] KOG0600 Cdc2-related protein kinase 143 9e-34
7300773 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase... 142 1e-33
7298087 [T] KOG0660 Mitogen-activated protein kinase 141 3e-33
Hs7706059 [R] KOG0593 Predicted protein kinase KKIAMRE 141 4e-33
Hs4758652 [R] KOG0593 Predicted protein kinase KKIAMRE 140 5e-33
At4g19110 [T] KOG0661 MAPK related serine/threonine protein kinase 140 5e-33
ECU08g0230 [R] KOG0594 Protein kinase PCTAIRE and related kinases 140 6e-33
7301110 [T] KOG0660 Mitogen-activated protein kinase 140 6e-33
SPBC8D2.01 [G] KOG0658 Glycogen synthase kinase-3 139 1e-32
ECU08g1790 [D] KOG0600 Cdc2-related protein kinase 137 5e-32
CE11556 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase... 137 5e-32
YPL042c [K] KOG0666 Cyclin C-dependent kinase CDK8 136 9e-32
At3g59790 [T] KOG0660 Mitogen-activated protein kinase 136 9e-32
SPAC1687.15 [G] KOG0658 Glycogen synthase kinase-3 135 1e-31
At2g43790 [T] KOG0660 Mitogen-activated protein kinase 135 1e-31
At1g10210 [T] KOG0660 Mitogen-activated protein kinase 135 1e-31
Hs20986501 [T] KOG0660 Mitogen-activated protein kinase 135 3e-31
Hs20986497 [T] KOG0660 Mitogen-activated protein kinase 135 3e-31
CE18608 [R] KOG0594 Protein kinase PCTAIRE and related kinases 135 3e-31
At3g45640 [T] KOG0660 Mitogen-activated protein kinase 134 6e-31
7297009 [R] KOG0593 Predicted protein kinase KKIAMRE 133 7e-31
CE28918 [R] KOG0594 Protein kinase PCTAIRE and related kinases 133 1e-30
7295173 [T] KOG0664 Nemo-like MAPK-related serine/threonine prot... 132 2e-30
CE29478 [T] KOG0664 Nemo-like MAPK-related serine/threonine prot... 132 2e-30
CE29477 [T] KOG0664 Nemo-like MAPK-related serine/threonine prot... 132 2e-30
CE29476 [T] KOG0664 Nemo-like MAPK-related serine/threonine prot... 132 2e-30
At4g36450 [T] KOG0660 Mitogen-activated protein kinase 132 2e-30
At1g59580 [T] KOG0660 Mitogen-activated protein kinase 131 3e-30
CE17815 [K] KOG0666 Cyclin C-dependent kinase CDK8 131 4e-30
Hs7106269 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymera... 130 5e-30
Hs7657498 [T] KOG0661 MAPK related serine/threonine protein kinase 130 6e-30
Hs7706445 [T] KOG0664 Nemo-like MAPK-related serine/threonine pr... 130 8e-30
Hs16936530 [R] KOG0594 Protein kinase PCTAIRE and related kinases 129 1e-29
CE06762 [T] KOG0660 Mitogen-activated protein kinase 129 1e-29
At2g18170 [T] KOG0660 Mitogen-activated protein kinase 129 1e-29
CE26988 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase... 129 1e-29
CE24971 [T] KOG0660 Mitogen-activated protein kinase 129 1e-29
CE01583 [T] KOG0660 Mitogen-activated protein kinase 129 1e-29
YGR040w [T] KOG0660 Mitogen-activated protein kinase 128 3e-29
Hs20128774 [T] KOG0660 Mitogen-activated protein kinase 128 3e-29
Hs17461944 [R] KOG0593 Predicted protein kinase KKIAMRE 128 3e-29
CE21401 [G] KOG0658 Glycogen synthase kinase-3 128 3e-29
CE20258 [R] KOG0593 Predicted protein kinase KKIAMRE 128 3e-29
Hs4506091 [T] KOG0660 Mitogen-activated protein kinase 127 4e-29
YLR113w [T] KOG0660 Mitogen-activated protein kinase 127 5e-29
Hs20562757 [T] KOG0660 Mitogen-activated protein kinase 127 5e-29
ECU11g1290 [R] KOG0663 Protein kinase PITSLRE and related kinases 127 5e-29
CE08727 [G] KOG0658 Glycogen synthase kinase-3 127 7e-29
CE02602_1 [T] KOG0660 Mitogen-activated protein kinase 127 7e-29
SPAC31G5.09c [T] KOG0660 Mitogen-activated protein kinase 126 9e-29
Hs20986512 [T] KOG0660 Mitogen-activated protein kinase 126 9e-29
At3g61160 [G] KOG0658 Glycogen synthase kinase-3 126 9e-29
7290342 [G] KOG0658 Glycogen synthase kinase-3 126 9e-29
SPBPI064 [G] KOG0658 Glycogen synthase kinase-3 126 1e-28
YPR054w [T] KOG0660 Mitogen-activated protein kinase 125 2e-28
At1g07880 [T] KOG0660 Mitogen-activated protein kinase 125 2e-28
SPAC23H4.17c [K] KOG0666 Cyclin C-dependent kinase CDK8 125 2e-28
YMR139w [G] KOG0658 Glycogen synthase kinase-3 125 3e-28
Hs20986531 [T] KOG0660 Mitogen-activated protein kinase 124 3e-28
Hs20986529 [T] KOG0660 Mitogen-activated protein kinase 124 6e-28
At1g53510 [T] KOG0660 Mitogen-activated protein kinase 123 8e-28
Hs4503069 [T] KOG0660 Mitogen-activated protein kinase 122 1e-27
CE06686 [T] KOG0660 Mitogen-activated protein kinase 122 1e-27
Hs20986516 [T] KOG0660 Mitogen-activated protein kinase 122 2e-27
Hs20986514 [T] KOG0660 Mitogen-activated protein kinase 122 2e-27
SPAC24B11.06c [T] KOG0660 Mitogen-activated protein kinase 122 2e-27
At4g11330 [T] KOG0660 Mitogen-activated protein kinase 122 2e-27
At2g46070 [T] KOG0660 Mitogen-activated protein kinase 122 2e-27
At2g42880 [T] KOG0660 Mitogen-activated protein kinase 122 2e-27
At4g18710 [G] KOG0658 Glycogen synthase kinase-3 121 3e-27
At3g05840 [G] KOG0658 Glycogen synthase kinase-3 121 4e-27
At1g57870 [G] KOG0658 Glycogen synthase kinase-3 121 4e-27
Hs21237745 [T] KOG0665 Jun-N-terminal kinase (JNK) 120 5e-27
CE17062 [T] KOG0660 Mitogen-activated protein kinase 120 5e-27
At5g19010 [T] KOG0660 Mitogen-activated protein kinase 120 5e-27
Hs4506089 [T] KOG0660 Mitogen-activated protein kinase 120 6e-27
Hs21237736 [T] KOG0665 Jun-N-terminal kinase (JNK) 120 6e-27
At3g18040 [T] KOG0660 Mitogen-activated protein kinase 120 6e-27
At3g14720 [T] KOG0660 Mitogen-activated protein kinase 120 6e-27
At1g06390 [G] KOG0658 Glycogen synthase kinase-3 120 6e-27
At5g26751 [G] KOG0658 Glycogen synthase kinase-3 120 8e-27
CE29020 [T] KOG0660 Mitogen-activated protein kinase 119 1e-26
YNL307c [G] KOG0658 Glycogen synthase kinase-3 118 2e-26
HsM20070143 [T] KOG0665 Jun-N-terminal kinase (JNK) 118 2e-26
Hs17452757 [UT] KOG0662 Cyclin-dependent kinase CDK5 117 4e-26
SPBC119.08 [T] KOG0660 Mitogen-activated protein kinase 117 7e-26
Hs22051130 [G] KOG0658 Glycogen synthase kinase-3 117 7e-26
Hs21361340 [G] KOG0658 Glycogen synthase kinase-3 117 7e-26
Hs11995474 [G] KOG0658 Glycogen synthase kinase-3 117 7e-26
Hs21237742 [T] KOG0665 Jun-N-terminal kinase (JNK) 116 9e-26
At2g30980 [G] KOG0658 Glycogen synthase kinase-3 116 9e-26
Hs4506081 [T] KOG0665 Jun-N-terminal kinase (JNK) 116 1e-25
Hs21237739 [T] KOG0665 Jun-N-terminal kinase (JNK) 116 1e-25
Hs20986510 [T] KOG0665 Jun-N-terminal kinase (JNK) 116 1e-25
Hs20986506 [T] KOG0665 Jun-N-terminal kinase (JNK) 116 1e-25
At4g01370 [T] KOG0660 Mitogen-activated protein kinase 116 1e-25
At1g18150 [T] KOG0660 Mitogen-activated protein kinase 116 1e-25
YHR030c [T] KOG0660 Mitogen-activated protein kinase 115 2e-25
SPAC3C7.06c [T] KOG0661 MAPK related serine/threonine protein ki... 115 2e-25
HsM4504163 [G] KOG0658 Glycogen synthase kinase-3 115 2e-25
YDL079c [G] KOG0658 Glycogen synthase kinase-3 115 3e-25
Hs20502986 [T] KOG0660 Mitogen-activated protein kinase 115 3e-25
At2g23070 [TDK] KOG0668 Casein kinase II alpha subunit 115 3e-25
CE27220 [T] KOG0660 Mitogen-activated protein kinase 114 4e-25
Hs20986499 [T] KOG0660 Mitogen-activated protein kinase 114 5e-25
At1g73670 [T] KOG0660 Mitogen-activated protein kinase 113 1e-24
SPBC8D2.19 [T] KOG0661 MAPK related serine/threonine protein kinase 112 1e-24
Hs20986521 [T] KOG0665 Jun-N-terminal kinase (JNK) 112 1e-24
Hs20986519 [T] KOG0665 Jun-N-terminal kinase (JNK) 112 1e-24
At4g00720 [G] KOG0658 Glycogen synthase kinase-3 112 1e-24
Hs4506095 [T] KOG0665 Jun-N-terminal kinase (JNK) 112 2e-24
Hs20986523 [T] KOG0665 Jun-N-terminal kinase (JNK) 112 2e-24
At1g09840 [G] KOG0658 Glycogen synthase kinase-3 112 2e-24
Hs4503097 [TDK] KOG0668 Casein kinase II alpha subunit 111 3e-24
CE29466 [T] KOG0665 Jun-N-terminal kinase (JNK) 110 5e-24
Hs4503095 [TDK] KOG0668 Casein kinase II alpha subunit 110 7e-24
At5g14640 [G] KOG0658 Glycogen synthase kinase-3 110 7e-24
At3g50000 [TDK] KOG0668 Casein kinase II alpha subunit 110 9e-24
At2g01450 [T] KOG0660 Mitogen-activated protein kinase 110 9e-24
At2g23080 [TDK] KOG0668 Casein kinase II alpha subunit 109 1e-23
7297631 [T] KOG0665 Jun-N-terminal kinase (JNK) 108 2e-23
CE27574 [T] KOG0665 Jun-N-terminal kinase (JNK) 107 4e-23
ECU07g1270 [G] KOG0658 Glycogen synthase kinase-3 107 7e-23
7289745 [TDK] KOG0668 Casein kinase II alpha subunit 106 1e-22
At5g67380 [TDK] KOG0668 Casein kinase II alpha subunit 105 2e-22
SPAC23C11.11 [TDK] KOG0668 Casein kinase II alpha subunit 105 3e-22
YIL035c [TDK] KOG0668 Casein kinase II alpha subunit 104 5e-22
CE17321 [TDK] KOG0668 Casein kinase II alpha subunit 103 8e-22
SPAC9G1.02 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 an... 101 3e-21
At1g63700 [T] KOG0198 MEKK and related serine/threonine protein ... 101 4e-21
CE17305 [T] KOG0665 Jun-N-terminal kinase (JNK) 100 7e-21
YJL106w [T] KOG0661 MAPK related serine/threonine protein kinase 100 1e-20
ECU05g1510 [TDK] KOG0668 Casein kinase II alpha subunit 99 2e-20
CE29318 [T] KOG0660 Mitogen-activated protein kinase 98 3e-20
Hs16306492 [R] KOG0594 Protein kinase PCTAIRE and related kinases 98 4e-20
Hs15011880 [T] KOG0201 Serine/threonine protein kinase 97 6e-20
CE19302_1 [G] KOG0658 Glycogen synthase kinase-3 97 6e-20
YOR061w [TDK] KOG0668 Casein kinase II alpha subunit 97 1e-19
At1g53570 [T] KOG0198 MEKK and related serine/threonine protein ... 97 1e-19
YAR019c [T] KOG0198 MEKK and related serine/threonine protein ki... 95 3e-19
Hs5454096 [T] KOG0574 STE20-like serine/threonine kinase MST 95 3e-19
At3g13530 [T] KOG0198 MEKK and related serine/threonine protein ... 94 5e-19
YOL128c [G] KOG0658 Glycogen synthase kinase-3 94 6e-19
SPBC1D7.05c [T] KOG0198 MEKK and related serine/threonine protei... 94 6e-19
At1g50230 [R] KOG0597 Serine-threonine protein kinase FUSED 94 6e-19
At1g09000 [T] KOG0198 MEKK and related serine/threonine protein ... 94 6e-19
7299437 [R] KOG0586 Serine/threonine protein kinase 94 6e-19
YKL161c [T] KOG0660 Mitogen-activated protein kinase 94 8e-19
SPBC21.06c [T] KOG0198 MEKK and related serine/threonine protein... 93 1e-18
Hs20986508 [T] KOG0665 Jun-N-terminal kinase (JNK) 93 1e-18
Hs16178962 [T] KOG0574 STE20-like serine/threonine kinase MST 93 1e-18
SPBC1604.14c [T] KOG0578 p21-activated serine/threonine protein ... 92 2e-18
Hs20070158 [T] KOG0201 Serine/threonine protein kinase 92 3e-18
Hs22050308_2 [T] KOG0198 MEKK and related serine/threonine prote... 92 3e-18
At3g01090 [T] KOG0583 Serine/threonine protein kinase 91 4e-18
Hs5454094 [T] KOG0574 STE20-like serine/threonine kinase MST 91 5e-18
At3g07980 [T] KOG0198 MEKK and related serine/threonine protein ... 91 5e-18
At1g54960 [T] KOG0198 MEKK and related serine/threonine protein ... 91 5e-18
7298004 [G] KOG0658 Glycogen synthase kinase-3 91 5e-18
YJL095w [T] KOG0198 MEKK and related serine/threonine protein ki... 90 9e-18
YCR073c [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and r... 90 9e-18
At5g66850 [T] KOG0198 MEKK and related serine/threonine protein ... 90 1e-17
At3g06030 [T] KOG0198 MEKK and related serine/threonine protein ... 90 1e-17
SPAC1F5.09c [T] KOG0578 p21-activated serine/threonine protein k... 89 2e-17
YLR362w [T] KOG0198 MEKK and related serine/threonine protein ki... 88 4e-17
HsM5729922 [T] KOG0198 MEKK and related serine/threonine protein... 88 4e-17
7300224 [T] KOG0201 Serine/threonine protein kinase 88 4e-17
Hs4505153 [T] KOG0198 MEKK and related serine/threonine protein ... 88 5e-17
Hs18552621 [R] KOG0597 Serine-threonine protein kinase FUSED 88 5e-17
CE07510 [T] KOG0201 Serine/threonine protein kinase 88 5e-17
CE27177 [T] KOG4279 Serine/threonine protein kinase 87 6e-17
At4g14480 [T] KOG0582 Ste20-like serine/threonine protein kinase 87 6e-17
Hs5922001 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 87 8e-17
CE20405 [G] KOG0658 Glycogen synthase kinase-3 87 8e-17
YGL179c [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kin... 87 1e-16
SPAC1D4.11c [T] KOG0671 LAMMER dual specificity kinases 87 1e-16
Hs4503429 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 87 1e-16
Hs6005810 [T] KOG0576 Mitogen-activated protein kinase kinase ki... 86 1e-16
Hs5174547 [T] KOG4279 Serine/threonine protein kinase 86 2e-16
CE27951 [T] KOG1094 Discoidin domain receptor DDR1 86 2e-16
CE27950 [T] KOG1094 Discoidin domain receptor DDR1 86 2e-16
CE05377 [G] KOG0658 Glycogen synthase kinase-3 86 2e-16
CE01612 [G] KOG0658 Glycogen synthase kinase-3 86 2e-16
SPAC23H4.02 [T] KOG0583 Serine/threonine protein kinase 86 2e-16
Hs5922004 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 86 2e-16
Hs5921999 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 86 2e-16
Hs4503427 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 86 2e-16
Hs20550209 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 86 2e-16
At5g39440 [T] KOG0583 Serine/threonine protein kinase 86 2e-16
At3g29160 [T] KOG0583 Serine/threonine protein kinase 86 2e-16
7293496 [R] KOG0597 Serine-threonine protein kinase FUSED 86 2e-16
CE27965 [T] KOG0574 STE20-like serine/threonine kinase MST 85 3e-16
CE27726 [T] KOG0574 STE20-like serine/threonine kinase MST 85 3e-16
CE27082 [T] KOG0574 STE20-like serine/threonine kinase MST 85 3e-16
CE07064 [T] KOG0574 STE20-like serine/threonine kinase MST 85 3e-16
CE23605 [T] KOG0665 Jun-N-terminal kinase (JNK) 85 4e-16
At1g53165 [T] KOG0201 Serine/threonine protein kinase 85 4e-16
CE28674 [T] KOG0201 Serine/threonine protein kinase 84 5e-16
SPAC1F3.02c [T] KOG0198 MEKK and related serine/threonine protei... 84 7e-16
Hs21735556 [T] KOG0198 MEKK and related serine/threonine protein... 84 7e-16
CE09532 [G] KOG0658 Glycogen synthase kinase-3 84 9e-16
YNR031c [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and r... 83 1e-15
HsM5454174 [T] KOG0201 Serine/threonine protein kinase 83 1e-15
Hs21361358 [T] KOG0201 Serine/threonine protein kinase 83 1e-15
Hs14589909 [T] KOG0576 Mitogen-activated protein kinase kinase k... 83 1e-15
7298142 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 83 1e-15
CE19219 [T] KOG0665 Jun-N-terminal kinase (JNK) 82 2e-15
CE28643 [T] KOG0583 Serine/threonine protein kinase 82 3e-15
CE07458 [T] KOG0583 Serine/threonine protein kinase 82 3e-15
7302464 [R] KOG0586 Serine/threonine protein kinase 82 3e-15
7302458 [T] KOG0574 STE20-like serine/threonine kinase MST 82 3e-15
7297633 [TU] KOG1026 Nerve growth factor receptor TRKA and relat... 82 3e-15
YHL007c [T] KOG0578 p21-activated serine/threonine protein kinase 82 3e-15
HsM4505103 [R] KOG0586 Serine/threonine protein kinase 82 3e-15
Hs4758702 [T] KOG4279 Serine/threonine protein kinase 82 3e-15
Hs7661994 [T] KOG0579 Ste20-like serine/threonine protein kinase 81 4e-15
CE05866 [G] KOG0658 Glycogen synthase kinase-3 81 4e-15
7304358 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 81 4e-15
Hs4507271 [T] KOG0583 Serine/threonine protein kinase 81 6e-15
Hs4506103 [J] KOG1033 eIF-2alpha kinase PEK/EIF2AK3 81 6e-15
At1g69220 [T] KOG0576 Mitogen-activated protein kinase kinase ki... 81 6e-15
Hs4505599 [T] KOG0578 p21-activated serine/threonine protein kinase 80 7e-15
Hs5453966 [T] KOG0583 Serine/threonine protein kinase 80 1e-14
Hs19923464 [T] KOG0577 Serine/threonine protein kinase 80 1e-14
Hs14150045 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase ... 80 1e-14
At5g14720 [T] KOG0582 Ste20-like serine/threonine protein kinase 80 1e-14
7299793 [T] KOG0583 Serine/threonine protein kinase 80 1e-14
CE27670 [T] KOG0578 p21-activated serine/threonine protein kinase 80 1e-14
CE04430 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 80 1e-14
YDR283c [J] KOG1035 eIF-2alpha kinase GCN2 79 2e-14
SPAC2F7.03c [R] KOG0667 Dual-specificity tyrosine-phosphorylatio... 79 2e-14
Hs4885661 [T] KOG0197 Tyrosine kinases 79 2e-14
Hs13569922 [R] KOG0611 Predicted serine/threonine protein kinase 79 2e-14
7290150 [T] KOG0583 Serine/threonine protein kinase 79 2e-14
Hs4885609 [T] KOG0197 Tyrosine kinases 79 2e-14
At3g15220 [T] KOG0201 Serine/threonine protein kinase 79 2e-14
7298926 [T] KOG0578 p21-activated serine/threonine protein kinase 79 2e-14
Hs4758222 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 79 3e-14
CE23751 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 79 3e-14
CE21086 [D] KOG0590 Checkpoint kinase and related serine/threoni... 79 3e-14
CE19878 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 79 3e-14
CE05897 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 79 3e-14
7300435 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and r... 79 3e-14
ECU03g0980 [T] KOG0583 Serine/threonine protein kinase 78 4e-14
At3g20860 [R] KOG0589 Serine/threonine protein kinase 78 4e-14
7298508 [T] KOG1989 ARK protein kinase family 78 4e-14
7293601 [T] KOG0577 Serine/threonine protein kinase 78 4e-14
Hs5174701 [T] KOG0579 Ste20-like serine/threonine protein kinase 78 5e-14
7300149 [T] KOG0578 p21-activated serine/threonine protein kinase 78 5e-14
7291778 [T] KOG0579 Ste20-like serine/threonine protein kinase 78 5e-14
SPAC1E11.03 [R] KOG0667 Dual-specificity tyrosine-phosphorylatio... 77 6e-14
7300559 [T] KOG4279 Serine/threonine protein kinase 77 6e-14
YHR102w [T] KOG0201 Serine/threonine protein kinase 77 8e-14
Hs4505601 [T] KOG0578 p21-activated serine/threonine protein kinase 77 8e-14
At5g50000 [T] KOG0192 Tyrosine kinase specific for activated (GT... 77 8e-14
At1g54510 [R] KOG0589 Serine/threonine protein kinase 77 8e-14
7301213 [R] KOG0589 Serine/threonine protein kinase 77 8e-14
YJL141c [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 77 1e-13
Hs7382496 [T] KOG0578 p21-activated serine/threonine protein kinase 76 1e-13
Hs5453974 [T] KOG0694 Serine/threonine protein kinase 76 1e-13
CE04172 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 76 1e-13
At5g60550 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase k... 76 1e-13
At3g63260 [T] KOG0192 Tyrosine kinase specific for activated (GT... 76 1e-13
SPCC18B5.11c [D] KOG0615 Serine/threonine protein kinase Chk2 an... 76 2e-13
Hs13430860 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 76 2e-13
CE02377 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 76 2e-13
At5g57630 [T] KOG0583 Serine/threonine protein kinase 76 2e-13
At4g08500 [T] KOG0198 MEKK and related serine/threonine protein ... 76 2e-13
SPBC17F3.02 [T] KOG0201 Serine/threonine protein kinase 75 2e-13
At3g59410 [J] KOG1035 eIF-2alpha kinase GCN2 75 2e-13
YAL017w [T] KOG1152 Signal transduction serine/threonine kinase ... 75 3e-13
Hs5031927 [TU] KOG1026 Nerve growth factor receptor TRKA and rel... 75 3e-13
Hs13186251 [T] KOG0200 Fibroblast/platelet-derived growth factor... 75 3e-13
Hs13186249 [T] KOG0200 Fibroblast/platelet-derived growth factor... 75 3e-13
Hs13186236 [T] KOG0200 Fibroblast/platelet-derived growth factor... 75 3e-13
Hs13186234 [T] KOG0200 Fibroblast/platelet-derived growth factor... 75 3e-13
Hs11276087 [T] KOG0200 Fibroblast/platelet-derived growth factor... 75 3e-13
CE19749 [T] KOG0665 Jun-N-terminal kinase (JNK) 75 3e-13
At3g61960 [OUT] KOG0595 Serine/threonine-protein kinase involved... 75 3e-13
7296749 [J] KOG1033 eIF-2alpha kinase PEK/EIF2AK3 75 3e-13
YDR466w [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 75 4e-13
Hs18765758 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 75 4e-13
Hs18765756 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 75 4e-13
Hs18765754 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 75 4e-13
Hs18765752 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 75 4e-13
Hs18765750 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 75 4e-13
CE28251 [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 75 4e-13
CE21615 [T] KOG0578 p21-activated serine/threonine protein kinase 75 4e-13
CE18454 [T] KOG4717 Serine/threonine protein kinase 75 4e-13
Hs11386209 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 74 5e-13
CE27297 [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 74 5e-13
At4g10730 [T] KOG0582 Ste20-like serine/threonine protein kinase 74 5e-13
At4g12020_6 [T] KOG0198 MEKK and related serine/threonine protei... 74 5e-13
At4g28980 [R] KOG0594 Protein kinase PCTAIRE and related kinases 74 7e-13
At3g50310 [T] KOG0198 MEKK and related serine/threonine protein ... 74 7e-13
Hs7706401 [T] KOG0577 Serine/threonine protein kinase 74 9e-13
Hs4759208 [T] KOG0577 Serine/threonine protein kinase 74 9e-13
CE25585 [T] KOG0193 Serine/threonine protein kinase RAF 74 9e-13
CE24993 [D] KOG0669 Cyclin T-dependent kinase CDK9 74 9e-13
CE01405 [T] KOG0577 Serine/threonine protein kinase 74 9e-13
At4g35780 [T] KOG0192 Tyrosine kinase specific for activated (GT... 74 9e-13
At2g17700 [T] KOG0192 Tyrosine kinase specific for activated (GT... 74 9e-13
Hs4505785 [G] KOG0599 Phosphorylase kinase gamma subunit 73 1e-12
Hs20128768 [OUT] KOG0595 Serine/threonine-protein kinase involve... 73 1e-12
Hs18581346 [T] KOG0660 Mitogen-activated protein kinase 73 1e-12
CE27768 [R] KOG0586 Serine/threonine protein kinase 73 1e-12
CE23838 [R] KOG0586 Serine/threonine protein kinase 73 1e-12
7298698 [T] KOG4250 TANK binding protein kinase TBK1 73 1e-12
7293666 [D] KOG0575 Polo-like serine/threonine protein kinase 73 1e-12
HsM8923212 [T] KOG4717 Serine/threonine protein kinase 73 2e-12
Hs4503823 [T] KOG0197 Tyrosine kinases 73 2e-12
At4g14780 [T] KOG0192 Tyrosine kinase specific for activated (GT... 72 2e-12
At3g22750 [T] KOG0192 Tyrosine kinase specific for activated (GT... 72 2e-12
7296450 [D] KOG0575 Polo-like serine/threonine protein kinase 72 2e-12
Hs4505475 [TU] KOG1026 Nerve growth factor receptor TRKA and rel... 72 3e-12
ECU11g1500 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 72 3e-12
Hs4502883_2 [T] KOG0671 LAMMER dual specificity kinases 72 3e-12
ECU08g1480 [R] KOG0586 Serine/threonine protein kinase 71 4e-12
SPAC1B9.02c [RT] KOG0598 Ribosomal protein S6 kinase and related... 71 6e-12
Hs4826878 [T] KOG0582 Ste20-like serine/threonine protein kinase 71 6e-12
At4g02010 [T] KOG1187 Serine/threonine protein kinase 71 6e-12
At3g01490 [T] KOG0192 Tyrosine kinase specific for activated (GT... 71 6e-12
7303915 [T] KOG0694 Serine/threonine protein kinase 71 6e-12
7303914 [T] KOG0694 Serine/threonine protein kinase 71 6e-12
Hs20543419_2 [T] KOG1095 Protein tyrosine kinase 71 6e-12
YDL159w [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K) 70 8e-12
Hs21361643 [T] KOG4717 Serine/threonine protein kinase 70 8e-12
CE26212 [T] KOG0582 Ste20-like serine/threonine protein kinase 70 8e-12
CE28273 [T] KOG0587 Traf2- and Nck-interacting kinase and relate... 70 1e-11
CE25673 [T] KOG0587 Traf2- and Nck-interacting kinase and relate... 70 1e-11
CE25672 [T] KOG0587 Traf2- and Nck-interacting kinase and relate... 70 1e-11
Hs4557747_2 [T] KOG1095 Protein tyrosine kinase 70 1e-11
Hs22065797 [T] KOG0577 Serine/threonine protein kinase 69 2e-11
CE20636 [D] KOG0590 Checkpoint kinase and related serine/threoni... 69 2e-11
CE12478 [D] KOG0590 Checkpoint kinase and related serine/threoni... 69 2e-11
Hs5453814 [T] KOG1094 Discoidin domain receptor DDR1 69 2e-11
Hs4503709 [T] KOG0200 Fibroblast/platelet-derived growth factor ... 69 2e-11
Hs13186269 [T] KOG0200 Fibroblast/platelet-derived growth factor... 69 2e-11
Hs13186265 [T] KOG0200 Fibroblast/platelet-derived growth factor... 69 2e-11
Hs13186263 [T] KOG0200 Fibroblast/platelet-derived growth factor... 69 2e-11
Hs13186261 [T] KOG0200 Fibroblast/platelet-derived growth factor... 69 2e-11
Hs13186259 [T] KOG0200 Fibroblast/platelet-derived growth factor... 69 2e-11
Hs13186255 [T] KOG0200 Fibroblast/platelet-derived growth factor... 69 2e-11
Hs13186253 [T] KOG0200 Fibroblast/platelet-derived growth factor... 69 2e-11
Hs13186243 [T] KOG0200 Fibroblast/platelet-derived growth factor... 69 2e-11
At1g70740 [T] KOG1187 Serine/threonine protein kinase 69 2e-11
YNL298w [T] KOG0578 p21-activated serine/threonine protein kinase 69 3e-11
Hs4885231 [T] KOG0194 Protein tyrosine kinase 69 3e-11
At3g04810 [R] KOG0589 Serine/threonine protein kinase 69 3e-11
7292679 [G] KOG0599 Phosphorylase kinase gamma subunit 69 3e-11
Hs19743898 [TU] KOG1026 Nerve growth factor receptor TRKA and re... 68 4e-11
CE29341 [T] KOG1095 Protein tyrosine kinase 68 4e-11
CE28667 [T] KOG1095 Protein tyrosine kinase 68 4e-11
CE23001 [R] KOG0589 Serine/threonine protein kinase 68 4e-11
At5g38560 [T] KOG1187 Serine/threonine protein kinase 68 4e-11
At1g49180_1 [OUT] KOG0595 Serine/threonine-protein kinase involv... 68 4e-11
YDR523c [T] KOG0201 Serine/threonine protein kinase 68 5e-11
YOL113w [T] KOG0578 p21-activated serine/threonine protein kinase 67 6e-11
Hs4503711 [T] KOG0200 Fibroblast/platelet-derived growth factor ... 67 6e-11
Hs14771959 [T] KOG0578 p21-activated serine/threonine protein ki... 67 6e-11
Hs13112048 [T] KOG0200 Fibroblast/platelet-derived growth factor... 67 6e-11
CE18699 [T] KOG0694 Serine/threonine protein kinase 67 6e-11
CE06352 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 67 6e-11
CE05549 [T] KOG0671 LAMMER dual specificity kinases 67 6e-11
At5g67080 [T] KOG0198 MEKK and related serine/threonine protein ... 67 6e-11
At5g28290 [R] KOG0589 Serine/threonine protein kinase 67 6e-11
YOL100w [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 67 8e-11
Hs7669485 [T] KOG1094 Discoidin domain receptor DDR1 67 8e-11
Hs7019543 [T] KOG0582 Ste20-like serine/threonine protein kinase 67 8e-11
YDR247w [T] KOG0583 Serine/threonine protein kinase 67 1e-10
At2g45490 [D] KOG0580 Serine/threonine protein kinase 67 1e-10
Hs9910476 [T] KOG0578 p21-activated serine/threonine protein kinase 66 1e-10
Hs7669487 [T] KOG1094 Discoidin domain receptor DDR1 66 1e-10
Hs7669483 [T] KOG1094 Discoidin domain receptor DDR1 66 1e-10
CE19788 [T] KOG1095 Protein tyrosine kinase 66 1e-10
CE01554 [T] KOG0986 G protein-coupled receptor kinase 66 1e-10
At3g12200 [R] KOG0589 Serine/threonine protein kinase 66 1e-10
At1g76370 [T] KOG1187 Serine/threonine protein kinase 66 1e-10
Hs5453882 [G] KOG0599 Phosphorylase kinase gamma subunit 66 2e-10
Hs5031689 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD... 66 2e-10
Hs4502885_2 [T] KOG0671 LAMMER dual specificity kinases 66 2e-10
SPBC4F6.06 [T] KOG0583 Serine/threonine protein kinase 65 2e-10
HsM5453812 [TU] KOG1026 Nerve growth factor receptor TRKA and re... 65 2e-10
Hs4506075 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD... 65 2e-10
Hs4506073 [T] KOG0694 Serine/threonine protein kinase 65 2e-10
Hs22050729 [T] KOG0200 Fibroblast/platelet-derived growth factor... 65 2e-10
>YPR161c [D] KOG0600 Cdc2-related protein kinase
Length = 657
Score = 608 bits (1569), Expect = e-174
Identities = 326/624 (52%), Positives = 405/624 (64%), Gaps = 49/624 (7%)
Query: 12 KYKIGKVKQIPTVVKDDKTGLEYIQVQSRENEKVYGVTKFLNNYREEEKLGQGTFGEVFK 71
KYKIGKVK P + +D KT L YI+++ R +EKVYG T F N+YRE+EKLGQGTFGEV+K
Sbjct: 17 KYKIGKVKSTPAIQRDAKTNLTYIKLRKRSSEKVYGCTVFQNHYREDEKLGQGTFGEVYK 76
Query: 72 GIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNHKNIVKLIEIVYDESPTPKTD 131
GIHL T R+VA+K+I+V EKDLFPITAQREITILKR+NHKNI+KLIE+VYD SP
Sbjct: 77 GIHLETQRQVAMKKIIVSVEKDLFPITAQREITILKRLNHKNIIKLIEMVYDHSPDITNA 136
Query: 132 STSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGLLHNPRVEFGMADVKNIMLQ 191
++S N H K F+MILPYMV+DL+G+LHNPR+ M D+KN+MLQ
Sbjct: 137 ASS-----NLH-------------KSFYMILPYMVADLSGVLHNPRINLEMCDIKNMMLQ 178
Query: 192 LLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLARNYYGSPPNLKYPGGAGSGAK 251
+LEG+NYIHC KF+HRDIKTANILIDH GV+K+ADFGLAR YYG PPNLKYPGGAGSGAK
Sbjct: 179 ILEGLNYIHCAKFMHRDIKTANILIDHNGVLKLADFGLARLYYGCPPNLKYPGGAGSGAK 238
Query: 252 YTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFEKKPILQGQTDIDQGHVIFKL 311
YTSVVVTRWYRAPE+VLGD+ YTTAVDIWG+GCVFAEFFEKKPILQG+TDIDQGHVIFKL
Sbjct: 239 YTSVVVTRWYRAPELVLGDKQYTTAVDIWGVGCVFAEFFEKKPILQGKTDIDQGHVIFKL 298
Query: 312 MGTPSMDEWGLAYHLPGSELTKTNYKSTLQERFSKALNETGXXXXXXXXXXDPYKRVTAM 371
+GTP+ ++W +A +LPG+ELT TNYK TL+ERF K L+ETG DPYKR+TAM
Sbjct: 299 LGTPTEEDWAVARYLPGAELTTTNYKPTLRERFGKYLSETGLDFLGQLLALDPYKRLTAM 358
Query: 372 KAKKHPFFFEEPLPNAQLTLPNEECHESDIKRYKSEMNESMSQRPPSAPTGHTSTDNSIR 431
AK HP+F E+PLP+ ++TLP EE HE+DIKRYK EM++S+SQR P+AP GH
Sbjct: 359 SAKHHPWFKEDPLPSEKITLPTEESHEADIKRYKEEMHQSLSQRVPTAPRGHIVEKGESP 418
Query: 432 AVTGAAFPKEASIPKAPRPEHIKSTIPAQPSASRYNGAATQNIPKEPIP----------T 481
V +IP+ P+ + P++ ++ + + + + P P
Sbjct: 419 VVKNL-----GAIPRGPKKDDASFLPPSKNVLAKPPPSKIRELHQNPRPYHVNSGYAKTA 473
Query: 482 APLPKGPKNSIPTGPNKLPPNPRDSYASKYPAESRFGVNTRITTESYNAGKRYRN----- 536
P P P GPN N R S S P SR VN R E+ N +Y
Sbjct: 474 IPPPAAPAGVNRYGPNNSSRNNRFSGNSTAPNNSRNPVN-RFHPET-NVSSKYNKVPLPL 531
Query: 537 --RGGWETGRDSLNYNNNYAPPADRSHHPTIQRPSAPRGGSYPNRYQNQDYNTSRNTGYN 594
+ ++ + Y N +P R H+P P +Y Q+ N N YN
Sbjct: 532 GPQSRYQGNSNESRYKN--SPNDSRYHNPRYVNKPETNFNRQPQKYSRQESNAPINKNYN 589
Query: 595 ----QYSQAGD-RRSYRPGASENP 613
+ AGD + RP + P
Sbjct: 590 PSNGSRNMAGDHHQGSRPSHPQFP 613
>SPBC32H8.10 [D] KOG0600 Cdc2-related protein kinase
Length = 591
Score = 234 bits (597), Expect = 3e-61
Identities = 170/528 (32%), Positives = 251/528 (47%), Gaps = 57/528 (10%)
Query: 52 LNNYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNH 111
L +Y EKLG+GTFGEV+K + A+KRIL+ EK+ FPITA REI ILK + H
Sbjct: 33 LTDYHLMEKLGEGTFGEVYKSQRRKDGKVYALKRILMHTEKEGFPITAIREIKILKSIKH 92
Query: 112 KNIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTG 171
+NI+ P +D T R + + +M+ PYM DL+G
Sbjct: 93 ENII------------PLSDMTVVRADKKHRRRGS-----------IYMVTPYMDHDLSG 129
Query: 172 LLHNPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLAR 231
LL NP V+F +K M QL G Y+H LHRD+K AN+LID+ G++KIADFGLAR
Sbjct: 130 LLENPSVKFTEPQIKCYMKQLFAGTKYLHDQLILHRDLKAANLLIDNHGILKIADFGLAR 189
Query: 232 -----NYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVF 286
+Y P L P + +YT VVTRWYR+PE++LG+R YTTA+D+W +GC+
Sbjct: 190 VITEESYANKNPGLPPP----NRREYTGCVVTRWYRSPELLLGERRYTTAIDMWSVGCIM 245
Query: 287 AEFFEKKPILQGQTDIDQGHVIFKLMGTPSMDEWGLAYHLPGSELTKT--NYKSTLQERF 344
AE ++ +PILQG +D+DQ IF+L G+P+ LPG E ++ ++ TL+ F
Sbjct: 246 AEMYKGRPILQGSSDLDQLDKIFRLCGSPTQATMPNWEKLPGCEGVRSFPSHPRTLETAF 305
Query: 345 SKALNETGXXXXXXXXXXDPYKRVTAMKAKKHPFFFEEPLPNAQLTLPNEECHESDIKRY 404
+ +P +R++A A +H +F P P L + KR
Sbjct: 306 F-TFGKEMTSLCGAILTLNPDERLSASMALEHEYFTTPPYPANPSELQSYSASHEYDKRR 364
Query: 405 KSEMNESMSQRPPSAPTGHTSTDNSIRAVT----GAAFPKEASIPKAPRPEHIKS----- 455
K E ++ S G R + G P S P+ R + +
Sbjct: 365 KREQRDANSHAFEQTANGKRQFRFMTRGPSDPWYGIRRPNYNSQPQYQRGSYNREGGNMD 424
Query: 456 ---TIPAQPSASRYNGAATQNIPK---EPIPTAPLPKGPKNSIPTGPNKLPPNPRDSYAS 509
+ QP + T ++P+ E T + + +S G P S
Sbjct: 425 RSRNVNYQPKRQQNFKPLTSDLPQKNSEFSETNAMNQTSNHSHADGQRYYRPEQDRSQRL 484
Query: 510 KYPAESRFGVNTRITTES----YNAGKRYRNRGGWE-TGRDSLNYNNN 552
+ P++ +G R +++S +N RY+N + T R S N + N
Sbjct: 485 RNPSD--YGRQGRQSSQSQQPAWNVSSRYQNNSKVQTTSRASENADTN 530
>7291442 [D] KOG0669 Cyclin T-dependent kinase CDK9
Length = 404
Score = 226 bits (576), Expect = 8e-59
Identities = 137/339 (40%), Positives = 192/339 (56%), Gaps = 37/339 (10%)
Query: 53 NNYREEEKLGQGTFGEVFKGIHLGTNRK-VAIKRILVRAEKDLFPITAQREITILKRMNH 111
N Y + K+GQGTFGEVFK N+K VA+K++L+ EK+ FPITA REI IL+ + H
Sbjct: 48 NKYEKVAKIGQGTFGEVFKAREKKGNKKFVAMKKVLMDNEKEGFPITALREIRILQLLKH 107
Query: 112 KNIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTG 171
+N+V LIEI +T +T+ Y F+++ + DL G
Sbjct: 108 ENVVNLIEIC-------RTKATA---TNGYRST-------------FYLVFDFCEHDLAG 144
Query: 172 LLHNPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLAR 231
LL N V+F + ++K +M QLL G+ YIH NK LHRD+K AN+LI G++K+ADFGLAR
Sbjct: 145 LLSNMNVKFSLGEIKKVMQQLLNGLYYIHSNKILHRDMKAANVLITKHGILKLADFGLAR 204
Query: 232 NYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFE 291
+ P N S +YT+ VVT WYR PE++LGDR+Y VD+WG GC+ AE +
Sbjct: 205 -AFSIPKN-------ESKNRYTNRVVTLWYRPPELLLGDRNYGPPVDMWGAGCIMAEMWT 256
Query: 292 KKPILQGQTDIDQGHVIFKLMGTPSMDEWGLAYHL---PGSELTKTNYKSTLQERFSKAL 348
+ PI+QG T+ Q I +L G+ + D W L EL K N K ++ER +
Sbjct: 257 RSPIMQGNTEQQQLTFISQLCGSFTPDVWPGVEELELYKSIELPK-NQKRRVKERLRPYV 315
Query: 349 -NETGXXXXXXXXXXDPYKRVTAMKAKKHPFFFEEPLPN 386
++TG DP KR+ A A H FF+ +P+P+
Sbjct: 316 KDQTGCDLLDKLLTLDPKKRIDADTALNHDFFWTDPMPS 354
>At5g10270 [D] KOG0600 Cdc2-related protein kinase
Length = 505
Score = 225 bits (574), Expect = 1e-58
Identities = 174/572 (30%), Positives = 263/572 (45%), Gaps = 97/572 (16%)
Query: 36 QVQSRENEKVYGVTKFLNNYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLF 95
Q+ E ++G ++ ++ + + E++G+GT+G+V+ + T VA+K+I + E++ F
Sbjct: 8 QLNLEEPPPIWG-SRSVDCFEKLEQIGEGTYGQVYMAKEIKTGEIVALKKIRMDNEREGF 66
Query: 96 PITAQREITILKRMNHKNIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITG 155
PITA REI ILK+++H+N+++L EIV SP D Y G
Sbjct: 67 PITAIREIKILKKLHHENVIQLKEIV--TSPGRDRDDQGKPDNNKYKGG----------- 113
Query: 156 KHFFMILPYMVSDLTGLLHNPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANIL 215
+M+ YM DLTGL P + F + +K M QLL G++Y H N+ LHRDIK +N+L
Sbjct: 114 --IYMVFEYMDHDLTGLADRPGLRFTVPQIKCYMKQLLTGLHYCHVNQVLHRDIKGSNLL 171
Query: 216 IDHKGVVKIADFGLARNY-YGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYT 274
ID++G +K+ADFGLAR+Y + NL T+ V+T WYR PE++LG Y
Sbjct: 172 IDNEGNLKLADFGLARSYSHDHTGNL------------TNRVITLWYRPPELLLGATKYG 219
Query: 275 TAVDIWGIGCVFAEFFEKKPILQGQTDIDQGHVIFKLMGTPSMDEWGLAYHLPGSELTK- 333
A+D+W +GC+FAE KPIL G+ + +Q + IF+L G+P W +P K
Sbjct: 220 PAIDMWSVGCIFAELLHAKPILPGKNEQEQLNKIFELCGSPDEKLWPGVSKMPWFNNFKP 279
Query: 334 -TNYKSTLQERFSKALNETGXXXXXXXXXXDPYKRVTAMKAKKHPFFFEEPLPNAQLTLP 392
K ++E F + + DP +R++A A +F+ +PLP +LP
Sbjct: 280 ARPLKRRVRE-FFRHFDRHALELLEKMLVLDPAQRISAKDALDAEYFWTDPLPCDPKSLP 338
Query: 393 N-EECHE--SDIKRYKSEMNESMSQRP--PSAPTGHTSTDNSIRAVTGAAFPKEASIPKA 447
E HE + KR + NE ++R P H+ A P + P
Sbjct: 339 TYESSHEFQTKKKRQQQRQNEEAAKRQKLQHPPLQHSRLPPLQHGGQSHAAPHWPAGPNH 398
Query: 448 PRPEHIKSTIPAQPSASRYNGAATQNIPKEPIPTAPLPKGPKNSIPTGPNKLPPNPRDSY 507
P + +PA PS + Y P+G P GPN+ PP+ S
Sbjct: 399 P-TNNAPPQVPAGPSHNFYG----------------KPRG-----PPGPNRYPPSGNQS- 435
Query: 508 ASKYPAESRFGVNTRITTESYNAGKRYRNRGGWETGRDSLNYNNNYAPPADRSHHPTIQR 567
G ++RGG+ +G PP R P +
Sbjct: 436 -----------------------GGYNQSRGGYSSGS---------YPPQGRG-APYVAG 462
Query: 568 PSAPRGGSY----PNRYQNQDYNTSRNTGYNQ 595
P P GG Y PN Q Y S ++G Q
Sbjct: 463 PRGPSGGPYGVGPPNYTQGGQYGGSGSSGRGQ 494
>At5g64960 [D] KOG0600 Cdc2-related protein kinase
Length = 513
Score = 221 bits (562), Expect = 3e-57
Identities = 161/528 (30%), Positives = 254/528 (47%), Gaps = 66/528 (12%)
Query: 36 QVQSRENEKVYGVTKFLNNYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLF 95
Q+ E ++G ++ ++ + + E++G+GT+G+V+ + T VA+K+I + E++ F
Sbjct: 8 QLNLEEPPPIWG-SRSVDCFEKLEQIGEGTYGQVYMAKEIKTGEIVALKKIRMDNEREGF 66
Query: 96 PITAQREITILKRMNHKNIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITG 155
PITA REI ILK+++H+N++ L EIV SP D Y G
Sbjct: 67 PITAIREIKILKKLHHENVIHLKEIV--TSPGRDRDDQGKPDNNKYKGG----------- 113
Query: 156 KHFFMILPYMVSDLTGLLHNPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANIL 215
+M+ YM DLTGL P + F + +K M QLL G++Y H N+ LHRDIK +N+L
Sbjct: 114 --IYMVFEYMDHDLTGLADRPGLRFTVPQIKCYMKQLLTGLHYCHVNQVLHRDIKGSNLL 171
Query: 216 IDHKGVVKIADFGLARNY-YGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYT 274
ID++G +K+ADFGLAR+Y + NL T+ V+T WYR PE++LG Y
Sbjct: 172 IDNEGNLKLADFGLARSYSHDHTGNL------------TNRVITLWYRPPELLLGATKYG 219
Query: 275 TAVDIWGIGCVFAEFFEKKPILQGQTDIDQGHVIFKLMGTPSMDEWGLAYHLPGSELTKT 334
A+D+W +GC+FAE KPIL G+T+ +Q + I++L G+P W +P K+
Sbjct: 220 PAIDMWSVGCIFAELLNGKPILPGKTENEQLNKIYELCGSPDESNWPGVSKMPWYNQMKS 279
Query: 335 N--YKSTLQERFSKALNETGXXXXXXXXXXDPYKRVTAMKAKKHPFFFEEPLPNAQLTLP 392
+ K ++E + + + DP +R+ A A +F+ +PLP +LP
Sbjct: 280 SRPLKRRVREIY-RHFDRHALELLEKMLVLDPSQRICAKDALDAEYFWTDPLPCDPKSLP 338
Query: 393 N-EECHESDIKRYKSEMNESMSQRPPSAPTGHTSTDNSIRAVTGAAFPKEASIPKAPRPE 451
E HE K+ + +M + + H +S P++ + ++
Sbjct: 339 TYESSHEFQTKKKRQQMRHN-EEAAKKQKLQHPQQQHS------RLPPQQHGVGQS---- 387
Query: 452 HIKSTIPAQPSASRYNGAATQNIPKEPIPTAPLPKG--PKNSIPTGPNKLPPN------- 502
H PA P N N P IP G P+ P PN+ PP+
Sbjct: 388 HAAPLWPAGP-----NHPMNNNAPPPQIPAGGHYYGGKPRGGAPV-PNRYPPSGNQTGGY 441
Query: 503 ---PRDSYAS-KYPAESR---FGVNTRITTESYNAGKRYRNRGGWETG 543
R Y+S YP + R +G R + Y G ++GG + G
Sbjct: 442 NNQSRGGYSSGAYPPQGRGAPYGAGPRGPSGGYGVGPPNYSQGGGQYG 489
>SPAC2F3.15 [D] KOG0600 Cdc2-related protein kinase
Length = 593
Score = 217 bits (553), Expect = 4e-56
Identities = 129/358 (36%), Positives = 190/358 (53%), Gaps = 47/358 (13%)
Query: 55 YREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNHKNI 114
Y + +++G+GT+G+V+K I+ T VA+KRI + EKD FPIT RE+ IL+R+ HKNI
Sbjct: 277 YEKIDQIGEGTYGKVYKAINTVTGDLVALKRIRLEQEKDGFPITTVREVKILQRLRHKNI 336
Query: 115 VKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGLLH 174
V+L+EI+ ++S +M+ YM DLTG+L
Sbjct: 337 VRLLEIMVEKSSV-------------------------------YMVFEYMDHDLTGVLL 365
Query: 175 NPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLARNYY 234
N ++ F ++K++ Q+ E + Y+H LHRDIK +NIL+++ G +K ADFGLAR
Sbjct: 366 NSQLHFTPGNIKHLSKQIFEALAYLHHRGVLHRDIKGSNILLNNNGDLKFADFGLARFNT 425
Query: 235 GSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFEKKP 294
S A YT+ V+T W+R PE++LG+ Y TAVDIW GC+ E F KP
Sbjct: 426 SS-----------KSANYTNRVITLWFRPPELLLGETAYDTAVDIWSAGCIVMELFTGKP 474
Query: 295 ILQGQTDIDQGHVIFKLMGTPSMDEWGLAYHLPGSELTK--TNYKSTLQERFSKALNETG 352
QG+ +I Q VI+ +MGTP + W +LP EL K KS E F + L+
Sbjct: 475 FFQGRDEISQLEVIYDMMGTPDVHSWPEVKNLPWYELLKPVEEKKSRFVETFKEILSPAA 534
Query: 353 XXXXXXXXXXDPYKRVTAMKAKKHPFF-FEEPLPNAQLTLPNEE--CHESDIKRYKSE 407
+P+ R +A + H +F E P P + L N + HE + K+ KS+
Sbjct: 535 IDLCQKLLALNPFCRPSAHETLMHEYFTSESPPPEPAVILKNMQGSWHEWESKKRKSK 592
>CE26422 [D] KOG0600 Cdc2-related protein kinase
Length = 684
Score = 217 bits (553), Expect = 4e-56
Identities = 131/388 (33%), Positives = 205/388 (52%), Gaps = 44/388 (11%)
Query: 52 LNNYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNH 111
L +Y +++G+GT+G+V+K ++ T +VA+KR+ + EK+ FPITA REI IL++++H
Sbjct: 308 LTHYTMLDQIGEGTYGQVYKAVNNLTGEQVALKRVRLENEKEGFPITAIREIKILRQLHH 367
Query: 112 KNIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTG 171
KNIV+L++IV D+ + T +F+++ Y+ DL G
Sbjct: 368 KNIVRLMDIVIDDISMDELKRTRA---------------------NFYLVFEYVDHDLIG 406
Query: 172 LLHNPR-VEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLA 230
LL + V+F + ++ QLLEG+ YIH FLHRDIK +NIL+++KG +KIAD GLA
Sbjct: 407 LLESKELVDFNKDQICSLFKQLLEGLAYIHNTGFLHRDIKCSNILVNNKGELKIADLGLA 466
Query: 231 RNYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFF 290
R + YT+ V+T WYR PE++LGD Y A+D+W GC+ E F
Sbjct: 467 RLW------------EKESRLYTNRVITLWYRPPELLLGDERYGPAIDVWSTGCMLGELF 514
Query: 291 EKKPILQGQTDIDQGHVIFKLMGTPSMDEWGLAYHLPG--SELTKTNYKSTLQERFSKAL 348
+KP+ G + Q +I K+ G+P++D W L G + K Y+ ++E F +
Sbjct: 515 TRKPLFNGNNEFGQLELISKVCGSPNVDNWPELTELVGWNTFRMKRTYQRRIREEFEHIM 574
Query: 349 NETGXXXXXXXXXXDPYKRVTAMKAKKHPFFFEEPLPNAQ-LTLP-NEECHESDIKRYKS 406
+P KR++A +A HP+ Q L LP +++CHE K+ K
Sbjct: 575 PREAVDLLDKMLTLNPEKRISAKEALNHPWIRSLEHTTVQPLKLPQHQDCHEMWSKKQKK 634
Query: 407 EMNESMSQRPPSAPTGHTSTDNSIRAVT 434
S R G + + +SIRA +
Sbjct: 635 ------SARLGRQAEGSSGSGHSIRATS 656
>Hs4502747 [D] KOG0669 Cyclin T-dependent kinase CDK9
Length = 372
Score = 216 bits (550), Expect = 9e-56
Identities = 127/344 (36%), Positives = 186/344 (53%), Gaps = 46/344 (13%)
Query: 52 LNNYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNH 111
++ Y + K+GQGTFGEVFK H T +KVA+K++L+ EK+ FPITA REI IL+ + H
Sbjct: 16 VSKYEKLAKIGQGTFGEVFKARHRKTGQKVALKKVLMENEKEGFPITALREIKILQLLKH 75
Query: 112 KNIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTG 171
+N+V LIEI T P G+ +++ + DL G
Sbjct: 76 ENVVNLIEIC----------RTKASPYNRCKGS-------------IYLVFDFCEHDLAG 112
Query: 172 LLHNPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLAR 231
LL N V+F ++++K +M LL G+ YIH NK LHRD+K AN+LI GV+K+ADFGLAR
Sbjct: 113 LLSNVLVKFTLSEIKRVMQMLLNGLYYIHRNKILHRDMKAANVLITRDGVLKLADFGLAR 172
Query: 232 NY---YGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAE 288
+ S PN +YT+ VVT WYR PE++LG+R Y +D+WG GC+ AE
Sbjct: 173 AFSLAKNSQPN-----------RYTNRVVTLWYRPPELLLGERDYGPPIDLWGAGCIMAE 221
Query: 289 FFEKKPILQGQTDIDQGHVIFKLMGT------PSMDEWGLAYHLPGSELTKTNYKSTLQE 342
+ + PI+QG T+ Q +I +L G+ P++D + L L EL K +
Sbjct: 222 MWTRSPIMQGNTEQHQLALISQLCGSITPEVWPNVDNYELYEKL---ELVKGQKRKVKDR 278
Query: 343 RFSKALNETGXXXXXXXXXXDPYKRVTAMKAKKHPFFFEEPLPN 386
+ + DP +R+ + A H FF+ +P+P+
Sbjct: 279 LKAYVRDPYALDLIDKLLVLDPAQRIDSDDALNHDFFWSDPMPS 322
>At1g67580 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 752
Score = 214 bits (546), Expect = 2e-55
Identities = 124/360 (34%), Positives = 197/360 (54%), Gaps = 49/360 (13%)
Query: 52 LNNYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNH 111
++ + K+ +GT+G V++ T VA+K++ + E++ FP+T+ REI IL +H
Sbjct: 403 VDEFERLNKIDEGTYGVVYRAKDKKTGEIVALKKVKMEKEREGFPLTSLREINILLSFHH 462
Query: 112 KNIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTG 171
+IV + E+V S DS FM++ YM DL
Sbjct: 463 PSIVDVKEVVVGSS----LDS-------------------------IFMVMEYMEHDLKA 493
Query: 172 LLHNPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLAR 231
L+ + F ++VK +MLQLLEG+ Y+H N LHRD+KT+N+L++++G +KI DFGLAR
Sbjct: 494 LMETMKQRFSQSEVKCLMLQLLEGVKYLHDNWVLHRDLKTSNLLLNNRGELKICDFGLAR 553
Query: 232 NYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFE 291
Y GSP LK YT +VVT WYRAPE++LG + Y+TA+D+W +GC+ AE
Sbjct: 554 QY-GSP--LK---------PYTHLVVTLWYRAPELLLGAKQYSTAIDMWSLGCIMAELLM 601
Query: 292 KKPILQGQTDIDQGHVIFKLMGTPSMDEWGLAYHLPGSELTKTNYK-STLQERF------ 344
K P+ G+T+ DQ IF+++GTP+ W LPG ++ ++ + L+++F
Sbjct: 602 KAPLFNGKTEFDQLDKIFRILGTPNESIWPGFSKLPGVKVNFVKHQYNLLRKKFPATSFT 661
Query: 345 -SKALNETGXXXXXXXXXXDPYKRVTAMKAKKHPFFFEEPLPNAQLTLPNEECHESDIKR 403
+ L++ G DP +R+T +A KH +F E PLP ++ +P + +R
Sbjct: 662 GAPVLSDAGFDLLNKLLTYDPERRITVNEALKHDWFREVPLPKSKDFMPTFPAQHAQDRR 721
>Hs16357498 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 777
Score = 212 bits (539), Expect = 2e-54
Identities = 130/378 (34%), Positives = 200/378 (52%), Gaps = 48/378 (12%)
Query: 60 KLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNHKNIVKLIE 119
++ +GT+G V++ T+ VA+KR+ + EK+ FPIT+ REI + + H NIV + E
Sbjct: 425 RIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVRE 484
Query: 120 IVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGLLHNPRVE 179
IV VG +N K+ ++++ Y+ DL L+ +
Sbjct: 485 IV----------------VG-------SNMDKI------YIVMNYVEHDLKSLMETMKQP 515
Query: 180 FGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLARNYYGSPPN 239
F +VK +M+QLL G+ ++H N LHRD+KT+N+L+ H G++K+ DFGLAR YGSP
Sbjct: 516 FLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLARE-YGSP-- 572
Query: 240 LKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFEKKPILQGQ 299
LK YT VVVT+WYRAPE++LG + Y+TAVD+W +GC+F E +KP+ G
Sbjct: 573 LK---------AYTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGN 623
Query: 300 TDIDQGHVIFKLMGTPSMDEWGLAYHLP-GSELTKTNYK-STLQERFSKALNETGXXXXX 357
++IDQ + +FK +GTPS W LP ++T + + + L++RF L++ G
Sbjct: 624 SEIDQINKVFKELGTPSEKIWPGYSELPVVKKMTFSEHPYNNLRKRFGALLSDQGFDLMN 683
Query: 358 XXXXXDPYKRVTAMKAKKHPFFFEEPLPNAQLTLPNEECHESDIKRYKSEMNESMSQRPP 417
P +R++A KH +F E PLP P K + + S RPP
Sbjct: 684 KFLTYFPGRRISAEDGLKHEYFRETPLPIDPSMFPTWPA-----KSEQQRVKRGTSPRPP 738
Query: 418 SAPTGHTSTDNSIRAVTG 435
G++ + TG
Sbjct: 739 EGGLGYSQLGDDDLKETG 756
>Hs16357496 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 439
Score = 212 bits (539), Expect = 2e-54
Identities = 130/378 (34%), Positives = 200/378 (52%), Gaps = 48/378 (12%)
Query: 60 KLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNHKNIVKLIE 119
++ +GT+G V++ T+ VA+KR+ + EK+ FPIT+ REI + + H NIV + E
Sbjct: 87 RIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVRE 146
Query: 120 IVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGLLHNPRVE 179
IV VG +N K+ ++++ Y+ DL L+ +
Sbjct: 147 IV----------------VG-------SNMDKI------YIVMNYVEHDLKSLMETMKQP 177
Query: 180 FGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLARNYYGSPPN 239
F +VK +M+QLL G+ ++H N LHRD+KT+N+L+ H G++K+ DFGLAR YGSP
Sbjct: 178 FLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLARE-YGSP-- 234
Query: 240 LKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFEKKPILQGQ 299
LK YT VVVT WYRAPE++LG + Y+TAVD+W +GC+F E +KP+ G+
Sbjct: 235 LK---------AYTPVVVTLWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGK 285
Query: 300 TDIDQGHVIFKLMGTPSMDEWGLAYHLPG-SELTKTNYK-STLQERFSKALNETGXXXXX 357
++IDQ + +FK +GTPS W LP ++T + + + L++RF L++ G
Sbjct: 286 SEIDQINKVFKDLGTPSEKIWPGYSELPAVKKMTFSEHPYNNLRKRFGALLSDQGFDLMN 345
Query: 358 XXXXXDPYKRVTAMKAKKHPFFFEEPLPNAQLTLPNEECHESDIKRYKSEMNESMSQRPP 417
P +R++A KH +F E PLP P K + + S RPP
Sbjct: 346 KFLTYFPGRRISAEDGLKHEYFRETPLPIDPSMFPTWPA-----KSEQQRVKRGTSPRPP 400
Query: 418 SAPTGHTSTDNSIRAVTG 435
G++ + TG
Sbjct: 401 EGGLGYSQLGDDDLKETG 418
>Hs16357486 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 780
Score = 212 bits (539), Expect = 2e-54
Identities = 130/378 (34%), Positives = 200/378 (52%), Gaps = 48/378 (12%)
Query: 60 KLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNHKNIVKLIE 119
++ +GT+G V++ T+ VA+KR+ + EK+ FPIT+ REI + + H NIV + E
Sbjct: 428 RIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVRE 487
Query: 120 IVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGLLHNPRVE 179
IV VG +N K+ ++++ Y+ DL L+ +
Sbjct: 488 IV----------------VG-------SNMDKI------YIVMNYVEHDLKSLMETMKQP 518
Query: 180 FGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLARNYYGSPPN 239
F +VK +M+QLL G+ ++H N LHRD+KT+N+L+ H G++K+ DFGLAR YGSP
Sbjct: 519 FLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLARE-YGSP-- 575
Query: 240 LKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFEKKPILQGQ 299
LK YT VVVT+WYRAPE++LG + Y+TAVD+W +GC+F E +KP+ G
Sbjct: 576 LK---------AYTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGN 626
Query: 300 TDIDQGHVIFKLMGTPSMDEWGLAYHLP-GSELTKTNYK-STLQERFSKALNETGXXXXX 357
++IDQ + +FK +GTPS W LP ++T + + + L++RF L++ G
Sbjct: 627 SEIDQINKVFKELGTPSEKIWPGYSELPVVKKMTFSEHPYNNLRKRFGALLSDQGFDLMN 686
Query: 358 XXXXXDPYKRVTAMKAKKHPFFFEEPLPNAQLTLPNEECHESDIKRYKSEMNESMSQRPP 417
P +R++A KH +F E PLP P K + + S RPP
Sbjct: 687 KFLTYFPGRRISAEDGLKHEYFRETPLPIDPSMFPTWPA-----KSEQQRVKRGTSPRPP 741
Query: 418 SAPTGHTSTDNSIRAVTG 435
G++ + TG
Sbjct: 742 EGGLGYSQLGDDDLKETG 759
>Hs16357484 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 767
Score = 212 bits (539), Expect = 2e-54
Identities = 130/378 (34%), Positives = 200/378 (52%), Gaps = 48/378 (12%)
Query: 60 KLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNHKNIVKLIE 119
++ +GT+G V++ T+ VA+KR+ + EK+ FPIT+ REI + + H NIV + E
Sbjct: 415 RIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVRE 474
Query: 120 IVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGLLHNPRVE 179
IV VG +N K+ ++++ Y+ DL L+ +
Sbjct: 475 IV----------------VG-------SNMDKI------YIVMNYVEHDLKSLMETMKQP 505
Query: 180 FGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLARNYYGSPPN 239
F +VK +M+QLL G+ ++H N LHRD+KT+N+L+ H G++K+ DFGLAR YGSP
Sbjct: 506 FLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLARE-YGSP-- 562
Query: 240 LKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFEKKPILQGQ 299
LK YT VVVT+WYRAPE++LG + Y+TAVD+W +GC+F E +KP+ G
Sbjct: 563 LK---------AYTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGN 613
Query: 300 TDIDQGHVIFKLMGTPSMDEWGLAYHLP-GSELTKTNYK-STLQERFSKALNETGXXXXX 357
++IDQ + +FK +GTPS W LP ++T + + + L++RF L++ G
Sbjct: 614 SEIDQINKVFKELGTPSEKIWPGYSELPVVKKMTFSEHPYNNLRKRFGALLSDQGFDLMN 673
Query: 358 XXXXXDPYKRVTAMKAKKHPFFFEEPLPNAQLTLPNEECHESDIKRYKSEMNESMSQRPP 417
P +R++A KH +F E PLP P K + + S RPP
Sbjct: 674 KFLTYFPGRRISAEDGLKHEYFRETPLPIDPSMFPTWPA-----KSEQQRVKRGTSPRPP 728
Query: 418 SAPTGHTSTDNSIRAVTG 435
G++ + TG
Sbjct: 729 EGGLGYSQLGDDDLKETG 746
>Hs16357482 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 776
Score = 212 bits (539), Expect = 2e-54
Identities = 130/378 (34%), Positives = 200/378 (52%), Gaps = 48/378 (12%)
Query: 60 KLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNHKNIVKLIE 119
++ +GT+G V++ T+ VA+KR+ + EK+ FPIT+ REI + + H NIV + E
Sbjct: 424 RIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVRE 483
Query: 120 IVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGLLHNPRVE 179
IV VG +N K+ ++++ Y+ DL L+ +
Sbjct: 484 IV----------------VG-------SNMDKI------YIVMNYVEHDLKSLMETMKQP 514
Query: 180 FGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLARNYYGSPPN 239
F +VK +M+QLL G+ ++H N LHRD+KT+N+L+ H G++K+ DFGLAR YGSP
Sbjct: 515 FLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLARE-YGSP-- 571
Query: 240 LKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFEKKPILQGQ 299
LK YT VVVT+WYRAPE++LG + Y+TAVD+W +GC+F E +KP+ G
Sbjct: 572 LK---------AYTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGN 622
Query: 300 TDIDQGHVIFKLMGTPSMDEWGLAYHLP-GSELTKTNYK-STLQERFSKALNETGXXXXX 357
++IDQ + +FK +GTPS W LP ++T + + + L++RF L++ G
Sbjct: 623 SEIDQINKVFKELGTPSEKIWPGYSELPVVKKMTFSEHPYNNLRKRFGALLSDQGFDLMN 682
Query: 358 XXXXXDPYKRVTAMKAKKHPFFFEEPLPNAQLTLPNEECHESDIKRYKSEMNESMSQRPP 417
P +R++A KH +F E PLP P K + + S RPP
Sbjct: 683 KFLTYFPGRRISAEDGLKHEYFRETPLPIDPSMFPTWPA-----KSEQQRVKRGTSPRPP 737
Query: 418 SAPTGHTSTDNSIRAVTG 435
G++ + TG
Sbjct: 738 EGGLGYSQLGDDDLKETG 755
>Hs16357480 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 397
Score = 212 bits (539), Expect = 2e-54
Identities = 130/378 (34%), Positives = 200/378 (52%), Gaps = 48/378 (12%)
Query: 60 KLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNHKNIVKLIE 119
++ +GT+G V++ T+ VA+KR+ + EK+ FPIT+ REI + + H NIV + E
Sbjct: 45 RIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVRE 104
Query: 120 IVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGLLHNPRVE 179
IV VG +N K+ ++++ Y+ DL L+ +
Sbjct: 105 IV----------------VG-------SNMDKI------YIVMNYVEHDLKSLMETMKQP 135
Query: 180 FGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLARNYYGSPPN 239
F +VK +M+QLL G+ ++H N LHRD+KT+N+L+ H G++K+ DFGLAR YGSP
Sbjct: 136 FLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLARE-YGSP-- 192
Query: 240 LKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFEKKPILQGQ 299
LK YT VVVT+WYRAPE++LG + Y+TAVD+W +GC+F E +KP+ G
Sbjct: 193 LK---------AYTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGN 243
Query: 300 TDIDQGHVIFKLMGTPSMDEWGLAYHLP-GSELTKTNYK-STLQERFSKALNETGXXXXX 357
++IDQ + +FK +GTPS W LP ++T + + + L++RF L++ G
Sbjct: 244 SEIDQINKVFKELGTPSEKIWPGYSELPVVKKMTFSEHPYNNLRKRFGALLSDQGFDLMN 303
Query: 358 XXXXXDPYKRVTAMKAKKHPFFFEEPLPNAQLTLPNEECHESDIKRYKSEMNESMSQRPP 417
P +R++A KH +F E PLP P K + + S RPP
Sbjct: 304 KFLTYFPGRRISAEDGLKHEYFRETPLPIDPSMFPTWPA-----KSEQQRVKRGTSPRPP 358
Query: 418 SAPTGHTSTDNSIRAVTG 435
G++ + TG
Sbjct: 359 EGGLGYSQLGDDDLKETG 376
>Hs16332372 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 771
Score = 212 bits (539), Expect = 2e-54
Identities = 130/378 (34%), Positives = 200/378 (52%), Gaps = 48/378 (12%)
Query: 60 KLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNHKNIVKLIE 119
++ +GT+G V++ T+ VA+KR+ + EK+ FPIT+ REI + + H NIV + E
Sbjct: 419 RIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVRE 478
Query: 120 IVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGLLHNPRVE 179
IV VG +N K+ ++++ Y+ DL L+ +
Sbjct: 479 IV----------------VG-------SNMDKI------YIVMNYVEHDLKSLMETMKQP 509
Query: 180 FGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLARNYYGSPPN 239
F +VK +M+QLL G+ ++H N LHRD+KT+N+L+ H G++K+ DFGLAR YGSP
Sbjct: 510 FLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLARE-YGSP-- 566
Query: 240 LKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFEKKPILQGQ 299
LK YT VVVT WYRAPE++LG + Y+TAVD+W +GC+F E +KP+ G+
Sbjct: 567 LK---------AYTPVVVTLWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGK 617
Query: 300 TDIDQGHVIFKLMGTPSMDEWGLAYHLPG-SELTKTNYK-STLQERFSKALNETGXXXXX 357
++IDQ + +FK +GTPS W LP ++T + + + L++RF L++ G
Sbjct: 618 SEIDQINKVFKDLGTPSEKIWPGYSELPAVKKMTFSEHPYNNLRKRFGALLSDQGFDLMN 677
Query: 358 XXXXXDPYKRVTAMKAKKHPFFFEEPLPNAQLTLPNEECHESDIKRYKSEMNESMSQRPP 417
P +R++A KH +F E PLP P K + + S RPP
Sbjct: 678 KFLTYFPGRRISAEDGLKHEYFRETPLPIDPSMFPTWPA-----KSEQQRVKRGTSPRPP 732
Query: 418 SAPTGHTSTDNSIRAVTG 435
G++ + TG
Sbjct: 733 EGGLGYSQLGDDDLKETG 750
>Hs16332370 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 780
Score = 212 bits (539), Expect = 2e-54
Identities = 130/378 (34%), Positives = 200/378 (52%), Gaps = 48/378 (12%)
Query: 60 KLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNHKNIVKLIE 119
++ +GT+G V++ T+ VA+KR+ + EK+ FPIT+ REI + + H NIV + E
Sbjct: 428 RIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVRE 487
Query: 120 IVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGLLHNPRVE 179
IV VG +N K+ ++++ Y+ DL L+ +
Sbjct: 488 IV----------------VG-------SNMDKI------YIVMNYVEHDLKSLMETMKQP 518
Query: 180 FGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLARNYYGSPPN 239
F +VK +M+QLL G+ ++H N LHRD+KT+N+L+ H G++K+ DFGLAR YGSP
Sbjct: 519 FLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLARE-YGSP-- 575
Query: 240 LKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFEKKPILQGQ 299
LK YT VVVT WYRAPE++LG + Y+TAVD+W +GC+F E +KP+ G+
Sbjct: 576 LK---------AYTPVVVTLWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGK 626
Query: 300 TDIDQGHVIFKLMGTPSMDEWGLAYHLPG-SELTKTNYK-STLQERFSKALNETGXXXXX 357
++IDQ + +FK +GTPS W LP ++T + + + L++RF L++ G
Sbjct: 627 SEIDQINKVFKDLGTPSEKIWPGYSELPAVKKMTFSEHPYNNLRKRFGALLSDQGFDLMN 686
Query: 358 XXXXXDPYKRVTAMKAKKHPFFFEEPLPNAQLTLPNEECHESDIKRYKSEMNESMSQRPP 417
P +R++A KH +F E PLP P K + + S RPP
Sbjct: 687 KFLTYFPGRRISAEDGLKHEYFRETPLPIDPSMFPTWPA-----KSEQQRVKRGTSPRPP 741
Query: 418 SAPTGHTSTDNSIRAVTG 435
G++ + TG
Sbjct: 742 EGGLGYSQLGDDDLKETG 759
>Hs16332368 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 461
Score = 212 bits (539), Expect = 2e-54
Identities = 130/378 (34%), Positives = 200/378 (52%), Gaps = 48/378 (12%)
Query: 60 KLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNHKNIVKLIE 119
++ +GT+G V++ T+ VA+KR+ + EK+ FPIT+ REI + + H NIV + E
Sbjct: 109 RIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVRE 168
Query: 120 IVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGLLHNPRVE 179
IV VG +N K+ ++++ Y+ DL L+ +
Sbjct: 169 IV----------------VG-------SNMDKI------YIVMNYVEHDLKSLMETMKQP 199
Query: 180 FGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLARNYYGSPPN 239
F +VK +M+QLL G+ ++H N LHRD+KT+N+L+ H G++K+ DFGLAR YGSP
Sbjct: 200 FLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLARE-YGSP-- 256
Query: 240 LKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFEKKPILQGQ 299
LK YT VVVT WYRAPE++LG + Y+TAVD+W +GC+F E +KP+ G+
Sbjct: 257 LK---------AYTPVVVTLWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGK 307
Query: 300 TDIDQGHVIFKLMGTPSMDEWGLAYHLPG-SELTKTNYK-STLQERFSKALNETGXXXXX 357
++IDQ + +FK +GTPS W LP ++T + + + L++RF L++ G
Sbjct: 308 SEIDQINKVFKDLGTPSEKIWPGYSELPAVKKMTFSEHPYNNLRKRFGALLSDQGFDLMN 367
Query: 358 XXXXXDPYKRVTAMKAKKHPFFFEEPLPNAQLTLPNEECHESDIKRYKSEMNESMSQRPP 417
P +R++A KH +F E PLP P K + + S RPP
Sbjct: 368 KFLTYFPGRRISAEDGLKHEYFRETPLPIDPSMFPTWPA-----KSEQQRVKRGTSPRPP 422
Query: 418 SAPTGHTSTDNSIRAVTG 435
G++ + TG
Sbjct: 423 EGGLGYSQLGDDDLKETG 440
>Hs16332366 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 565
Score = 212 bits (539), Expect = 2e-54
Identities = 130/378 (34%), Positives = 200/378 (52%), Gaps = 48/378 (12%)
Query: 60 KLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNHKNIVKLIE 119
++ +GT+G V++ T+ VA+KR+ + EK+ FPIT+ REI + + H NIV + E
Sbjct: 213 RIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVRE 272
Query: 120 IVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGLLHNPRVE 179
IV VG +N K+ ++++ Y+ DL L+ +
Sbjct: 273 IV----------------VG-------SNMDKI------YIVMNYVEHDLKSLMETMKQP 303
Query: 180 FGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLARNYYGSPPN 239
F +VK +M+QLL G+ ++H N LHRD+KT+N+L+ H G++K+ DFGLAR YGSP
Sbjct: 304 FLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLARE-YGSP-- 360
Query: 240 LKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFEKKPILQGQ 299
LK YT VVVT WYRAPE++LG + Y+TAVD+W +GC+F E +KP+ G+
Sbjct: 361 LK---------AYTPVVVTLWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGK 411
Query: 300 TDIDQGHVIFKLMGTPSMDEWGLAYHLPG-SELTKTNYK-STLQERFSKALNETGXXXXX 357
++IDQ + +FK +GTPS W LP ++T + + + L++RF L++ G
Sbjct: 412 SEIDQINKVFKDLGTPSEKIWPGYSELPAVKKMTFSEHPYNNLRKRFGALLSDQGFDLMN 471
Query: 358 XXXXXDPYKRVTAMKAKKHPFFFEEPLPNAQLTLPNEECHESDIKRYKSEMNESMSQRPP 417
P +R++A KH +F E PLP P K + + S RPP
Sbjct: 472 KFLTYFPGRRISAEDGLKHEYFRETPLPIDPSMFPTWPA-----KSEQQRVKRGTSPRPP 526
Query: 418 SAPTGHTSTDNSIRAVTG 435
G++ + TG
Sbjct: 527 EGGLGYSQLGDDDLKETG 544
>Hs16332364 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 748
Score = 212 bits (539), Expect = 2e-54
Identities = 130/378 (34%), Positives = 200/378 (52%), Gaps = 48/378 (12%)
Query: 60 KLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNHKNIVKLIE 119
++ +GT+G V++ T+ VA+KR+ + EK+ FPIT+ REI + + H NIV + E
Sbjct: 396 RIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVRE 455
Query: 120 IVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGLLHNPRVE 179
IV VG +N K+ ++++ Y+ DL L+ +
Sbjct: 456 IV----------------VG-------SNMDKI------YIVMNYVEHDLKSLMETMKQP 486
Query: 180 FGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLARNYYGSPPN 239
F +VK +M+QLL G+ ++H N LHRD+KT+N+L+ H G++K+ DFGLAR YGSP
Sbjct: 487 FLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLARE-YGSP-- 543
Query: 240 LKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFEKKPILQGQ 299
LK YT VVVT WYRAPE++LG + Y+TAVD+W +GC+F E +KP+ G+
Sbjct: 544 LK---------AYTPVVVTLWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGK 594
Query: 300 TDIDQGHVIFKLMGTPSMDEWGLAYHLPG-SELTKTNYK-STLQERFSKALNETGXXXXX 357
++IDQ + +FK +GTPS W LP ++T + + + L++RF L++ G
Sbjct: 595 SEIDQINKVFKDLGTPSEKIWPGYSELPAVKKMTFSEHPYNNLRKRFGALLSDQGFDLMN 654
Query: 358 XXXXXDPYKRVTAMKAKKHPFFFEEPLPNAQLTLPNEECHESDIKRYKSEMNESMSQRPP 417
P +R++A KH +F E PLP P K + + S RPP
Sbjct: 655 KFLTYFPGRRISAEDGLKHEYFRETPLPIDPSMFPTWPA-----KSEQQRVKRGTSPRPP 709
Query: 418 SAPTGHTSTDNSIRAVTG 435
G++ + TG
Sbjct: 710 EGGLGYSQLGDDDLKETG 727
>Hs16332362 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 737
Score = 212 bits (539), Expect = 2e-54
Identities = 130/378 (34%), Positives = 200/378 (52%), Gaps = 48/378 (12%)
Query: 60 KLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNHKNIVKLIE 119
++ +GT+G V++ T+ VA+KR+ + EK+ FPIT+ REI + + H NIV + E
Sbjct: 385 RIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVRE 444
Query: 120 IVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGLLHNPRVE 179
IV VG +N K+ ++++ Y+ DL L+ +
Sbjct: 445 IV----------------VG-------SNMDKI------YIVMNYVEHDLKSLMETMKQP 475
Query: 180 FGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLARNYYGSPPN 239
F +VK +M+QLL G+ ++H N LHRD+KT+N+L+ H G++K+ DFGLAR YGSP
Sbjct: 476 FLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLARE-YGSP-- 532
Query: 240 LKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFEKKPILQGQ 299
LK YT VVVT WYRAPE++LG + Y+TAVD+W +GC+F E +KP+ G+
Sbjct: 533 LK---------AYTPVVVTLWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGK 583
Query: 300 TDIDQGHVIFKLMGTPSMDEWGLAYHLPG-SELTKTNYK-STLQERFSKALNETGXXXXX 357
++IDQ + +FK +GTPS W LP ++T + + + L++RF L++ G
Sbjct: 584 SEIDQINKVFKDLGTPSEKIWPGYSELPAVKKMTFSEHPYNNLRKRFGALLSDQGFDLMN 643
Query: 358 XXXXXDPYKRVTAMKAKKHPFFFEEPLPNAQLTLPNEECHESDIKRYKSEMNESMSQRPP 417
P +R++A KH +F E PLP P K + + S RPP
Sbjct: 644 KFLTYFPGRRISAEDGLKHEYFRETPLPIDPSMFPTWPA-----KSEQQRVKRGTSPRPP 698
Query: 418 SAPTGHTSTDNSIRAVTG 435
G++ + TG
Sbjct: 699 EGGLGYSQLGDDDLKETG 716
>Hs16332360 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 526
Score = 212 bits (539), Expect = 2e-54
Identities = 130/378 (34%), Positives = 200/378 (52%), Gaps = 48/378 (12%)
Query: 60 KLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNHKNIVKLIE 119
++ +GT+G V++ T+ VA+KR+ + EK+ FPIT+ REI + + H NIV + E
Sbjct: 174 RIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVRE 233
Query: 120 IVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGLLHNPRVE 179
IV VG +N K+ ++++ Y+ DL L+ +
Sbjct: 234 IV----------------VG-------SNMDKI------YIVMNYVEHDLKSLMETMKQP 264
Query: 180 FGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLARNYYGSPPN 239
F +VK +M+QLL G+ ++H N LHRD+KT+N+L+ H G++K+ DFGLAR YGSP
Sbjct: 265 FLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLARE-YGSP-- 321
Query: 240 LKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFEKKPILQGQ 299
LK YT VVVT WYRAPE++LG + Y+TAVD+W +GC+F E +KP+ G+
Sbjct: 322 LK---------AYTPVVVTLWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGK 372
Query: 300 TDIDQGHVIFKLMGTPSMDEWGLAYHLPG-SELTKTNYK-STLQERFSKALNETGXXXXX 357
++IDQ + +FK +GTPS W LP ++T + + + L++RF L++ G
Sbjct: 373 SEIDQINKVFKDLGTPSEKIWPGYSELPAVKKMTFSEHPYNNLRKRFGALLSDQGFDLMN 432
Query: 358 XXXXXDPYKRVTAMKAKKHPFFFEEPLPNAQLTLPNEECHESDIKRYKSEMNESMSQRPP 417
P +R++A KH +F E PLP P K + + S RPP
Sbjct: 433 KFLTYFPGRRISAEDGLKHEYFRETPLPIDPSMFPTWPA-----KSEQQRVKRGTSPRPP 487
Query: 418 SAPTGHTSTDNSIRAVTG 435
G++ + TG
Sbjct: 488 EGGLGYSQLGDDDLKETG 505
>Hs16332358 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 782
Score = 212 bits (539), Expect = 2e-54
Identities = 130/378 (34%), Positives = 200/378 (52%), Gaps = 48/378 (12%)
Query: 60 KLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNHKNIVKLIE 119
++ +GT+G V++ T+ VA+KR+ + EK+ FPIT+ REI + + H NIV + E
Sbjct: 430 RIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVRE 489
Query: 120 IVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGLLHNPRVE 179
IV VG +N K+ ++++ Y+ DL L+ +
Sbjct: 490 IV----------------VG-------SNMDKI------YIVMNYVEHDLKSLMETMKQP 520
Query: 180 FGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLARNYYGSPPN 239
F +VK +M+QLL G+ ++H N LHRD+KT+N+L+ H G++K+ DFGLAR YGSP
Sbjct: 521 FLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLARE-YGSP-- 577
Query: 240 LKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFEKKPILQGQ 299
LK YT VVVT WYRAPE++LG + Y+TAVD+W +GC+F E +KP+ G+
Sbjct: 578 LK---------AYTPVVVTLWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGK 628
Query: 300 TDIDQGHVIFKLMGTPSMDEWGLAYHLPG-SELTKTNYK-STLQERFSKALNETGXXXXX 357
++IDQ + +FK +GTPS W LP ++T + + + L++RF L++ G
Sbjct: 629 SEIDQINKVFKDLGTPSEKIWPGYSELPAVKKMTFSEHPYNNLRKRFGALLSDQGFDLMN 688
Query: 358 XXXXXDPYKRVTAMKAKKHPFFFEEPLPNAQLTLPNEECHESDIKRYKSEMNESMSQRPP 417
P +R++A KH +F E PLP P K + + S RPP
Sbjct: 689 KFLTYFPGRRISAEDGLKHEYFRETPLPIDPSMFPTWPA-----KSEQQRVKRGTSPRPP 743
Query: 418 SAPTGHTSTDNSIRAVTG 435
G++ + TG
Sbjct: 744 EGGLGYSQLGDDDLKETG 761
>Hs10835055 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 795
Score = 212 bits (539), Expect = 2e-54
Identities = 130/378 (34%), Positives = 200/378 (52%), Gaps = 48/378 (12%)
Query: 60 KLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNHKNIVKLIE 119
++ +GT+G V++ T+ VA+KR+ + EK+ FPIT+ REI + + H NIV + E
Sbjct: 443 RIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVRE 502
Query: 120 IVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGLLHNPRVE 179
IV VG +N K+ ++++ Y+ DL L+ +
Sbjct: 503 IV----------------VG-------SNMDKI------YIVMNYVEHDLKSLMETMKQP 533
Query: 180 FGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLARNYYGSPPN 239
F +VK +M+QLL G+ ++H N LHRD+KT+N+L+ H G++K+ DFGLAR YGSP
Sbjct: 534 FLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLARE-YGSP-- 590
Query: 240 LKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFEKKPILQGQ 299
LK YT VVVT WYRAPE++LG + Y+TAVD+W +GC+F E +KP+ G+
Sbjct: 591 LK---------AYTPVVVTLWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGK 641
Query: 300 TDIDQGHVIFKLMGTPSMDEWGLAYHLPG-SELTKTNYK-STLQERFSKALNETGXXXXX 357
++IDQ + +FK +GTPS W LP ++T + + + L++RF L++ G
Sbjct: 642 SEIDQINKVFKDLGTPSEKIWPGYSELPAVKKMTFSEHPYNNLRKRFGALLSDQGFDLMN 701
Query: 358 XXXXXDPYKRVTAMKAKKHPFFFEEPLPNAQLTLPNEECHESDIKRYKSEMNESMSQRPP 417
P +R++A KH +F E PLP P K + + S RPP
Sbjct: 702 KFLTYFPGRRISAEDGLKHEYFRETPLPIDPSMFPTWPA-----KSEQQRVKRGTSPRPP 756
Query: 418 SAPTGHTSTDNSIRAVTG 435
G++ + TG
Sbjct: 757 EGGLGYSQLGDDDLKETG 774
>Hs16357494 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 775
Score = 211 bits (537), Expect = 3e-54
Identities = 130/378 (34%), Positives = 199/378 (52%), Gaps = 48/378 (12%)
Query: 60 KLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNHKNIVKLIE 119
++ +GT+G V++ T+ VA+KR+ + E + FPIT+ REI + + H NIV + E
Sbjct: 423 RIEEGTYGVVYRAKDKKTDEIVALKRLKMEKENEGFPITSLREINTILKAQHPNIVTVRE 482
Query: 120 IVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGLLHNPRVE 179
IV VG +N K+ ++++ Y+ DL L+ +
Sbjct: 483 IV----------------VG-------SNMDKI------YIVMNYVEHDLKSLMETMKQP 513
Query: 180 FGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLARNYYGSPPN 239
F +VK +M+QLL G+ ++H N LHRD+KT+N+L+ H G++K+ DFGLAR YGSP
Sbjct: 514 FLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLARE-YGSP-- 570
Query: 240 LKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFEKKPILQGQ 299
LK YT VVVT+WYRAPE++LG + Y+TAVD+W +GC+F E +KP+ G
Sbjct: 571 LK---------AYTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGN 621
Query: 300 TDIDQGHVIFKLMGTPSMDEWGLAYHLP-GSELTKTNYK-STLQERFSKALNETGXXXXX 357
++IDQ + +FK +GTPS W LP ++T + + + L++RF L+E G
Sbjct: 622 SEIDQINKVFKELGTPSEKIWPGYSELPVVKKMTFSEHPYNNLRKRFGALLSEQGFDLMN 681
Query: 358 XXXXXDPYKRVTAMKAKKHPFFFEEPLPNAQLTLPNEECHESDIKRYKSEMNESMSQRPP 417
P +R++A KH +F E PLP P K + + S RPP
Sbjct: 682 KFLTYFPGRRISAEDGLKHEYFRETPLPIDPSMFPTWPA-----KSEQQRVKRGTSPRPP 736
Query: 418 SAPTGHTSTDNSIRAVTG 435
G++ + TG
Sbjct: 737 EGGLGYSQLGDDDLKETG 754
>Hs16357492 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 777
Score = 211 bits (537), Expect = 3e-54
Identities = 130/378 (34%), Positives = 199/378 (52%), Gaps = 48/378 (12%)
Query: 60 KLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNHKNIVKLIE 119
++ +GT+G V++ T+ VA+KR+ + E + FPIT+ REI + + H NIV + E
Sbjct: 425 RIEEGTYGVVYRAKDKKTDEIVALKRLKMEKENEGFPITSLREINTILKAQHPNIVTVRE 484
Query: 120 IVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGLLHNPRVE 179
IV VG +N K+ ++++ Y+ DL L+ +
Sbjct: 485 IV----------------VG-------SNMDKI------YIVMNYVEHDLKSLMETMKQP 515
Query: 180 FGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLARNYYGSPPN 239
F +VK +M+QLL G+ ++H N LHRD+KT+N+L+ H G++K+ DFGLAR YGSP
Sbjct: 516 FLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLARE-YGSP-- 572
Query: 240 LKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFEKKPILQGQ 299
LK YT VVVT+WYRAPE++LG + Y+TAVD+W +GC+F E +KP+ G
Sbjct: 573 LK---------AYTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGN 623
Query: 300 TDIDQGHVIFKLMGTPSMDEWGLAYHLP-GSELTKTNYK-STLQERFSKALNETGXXXXX 357
++IDQ + +FK +GTPS W LP ++T + + + L++RF L+E G
Sbjct: 624 SEIDQINKVFKELGTPSEKIWPGYSELPVVKKMTFSEHPYNNLRKRFGALLSEQGFDLMN 683
Query: 358 XXXXXDPYKRVTAMKAKKHPFFFEEPLPNAQLTLPNEECHESDIKRYKSEMNESMSQRPP 417
P +R++A KH +F E PLP P K + + S RPP
Sbjct: 684 KFLTYFPGRRISAEDGLKHEYFRETPLPIDPSMFPTWPA-----KSEQQRVKRGTSPRPP 738
Query: 418 SAPTGHTSTDNSIRAVTG 435
G++ + TG
Sbjct: 739 EGGLGYSQLGDDDLKETG 756
>CE23826 [D] KOG0669 Cyclin T-dependent kinase CDK9
Length = 489
Score = 211 bits (537), Expect = 3e-54
Identities = 131/401 (32%), Positives = 202/401 (49%), Gaps = 74/401 (18%)
Query: 42 NEKVYGVTKFLNNYREEEKLGQGTFG-----------EVFKGIHLGTNRKVAIKRILVRA 90
++ Y + ++ Y + K+GQGTFG EVFK T R VA+K+IL+
Sbjct: 72 DQATYPFIRDVSTYEKLNKIGQGTFGQVLQGRKSRNSEVFKARCKNTGRMVALKKILMEN 131
Query: 91 EKDLFPITAQREITILKRMNHKNIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQ 150
EK+ FPITA RE+ +L+++ H NI LIE+ S + G + A
Sbjct: 132 EKEGFPITALREVKMLEQLKHPNITDLIEVC------------SAKSTGTTGSKDRAT-- 177
Query: 151 KLITGKHFFMILPYMVSDLTGLLHNPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIK 210
F++++ DL GLL NP++ + +K +M L+ G+N +H +K LHRD+K
Sbjct: 178 -------FYLVMALCAHDLAGLLSNPKIRMSLVHIKTMMKHLMSGLNKLHRSKILHRDMK 230
Query: 211 TANILIDHKGVVKIADFGLARNYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGD 270
AN+LI G++K+ADFGLAR P ++ GAG YT+ VVT WYR PE++LGD
Sbjct: 231 AANVLISKDGILKLADFGLAR------PFVQRENGAGPRPLYTNRVVTLWYRPPELLLGD 284
Query: 271 RHYTTAVDIWGIGCVFAEFFEKKPILQGQTDIDQGHVIFKLMGTPSMDEWGLAYHL---- 326
R Y T +D+WG GC+ AE + ++PI+QG T+ Q +I L G+ + D W ++
Sbjct: 285 RQYGTKIDVWGAGCIMAEMWTRQPIMQGDTEQKQLQLISGLCGSINKDVWPNCVNMPLWS 344
Query: 327 -----PGSELTKTNYK---------------STLQERFSK-------ALNETGXXXXXXX 359
P S L + Y+ + + F K A ++
Sbjct: 345 AMSSEPNSALPQGKYRILPNKMKNLMKFDAPDSKTDPFGKNVKQHDSATDDDALHLLEIL 404
Query: 360 XXXDPYKRVTAMKAKKHPFFFEEPLPNAQL-----TLPNEE 395
DP KR T+ +A+ +FF++P+P A + T+PN +
Sbjct: 405 LAIDPDKRPTSDEAEDDIWFFKDPVPMANVQDLMDTIPNSQ 445
>7296451 [D] KOG0600 Cdc2-related protein kinase
Length = 1157
Score = 210 bits (535), Expect = 5e-54
Identities = 132/385 (34%), Positives = 202/385 (52%), Gaps = 39/385 (10%)
Query: 39 SRENEKVYGVTKFLNNYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPIT 98
SR N + +G + ++ + ++G+GT+G+V+K TN VA+K++ + EK+ FPIT
Sbjct: 789 SRNNVRDWG-ERCVDVFEMIAQIGEGTYGQVYKARDHHTNDMVALKKVRLEHEKEGFPIT 847
Query: 99 AQREITILKRMNHKNIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHF 158
A REI IL+++NH+NIV L EIV D K D+ R F
Sbjct: 848 AVREIKILRQLNHRNIVNLHEIVTD-----KQDAVEFRKDKG----------------SF 886
Query: 159 FMILPYMVSDLTGLLHNPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDH 218
+++ YM DL GLL + V+F + +IM QLL+G+NY H FLHRDIK +NIL+++
Sbjct: 887 YLVFEYMDHDLMGLLESGMVDFNEENNASIMKQLLDGLNYCHKKNFLHRDIKCSNILMNN 946
Query: 219 KGVVKIADFGLARNYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVD 278
+G VK+ADFGLAR Y YT+ V+T WYR PE++LG+ Y ++D
Sbjct: 947 RGKVKLADFGLARLYNADDRE----------RPYTNKVITLWYRPPELLLGEERYGPSID 996
Query: 279 IWGIGCVFAEFFEKKPILQGQTDIDQGHVIFKLMGTPSMDEWGLAYHLP--GSELTKTNY 336
+W GC+ E F K+P+ Q ++ Q I K+ G+P W LP + K +
Sbjct: 997 VWSCGCILGELFVKRPLFQANAEMAQLETISKICGSPVPAVWPNVIKLPLFHTLKQKKTH 1056
Query: 337 KSTLQERFSKALNETGXXXXXXXXXXDPYKRVTAMKAKKHPFFFE---EPLPNAQLTLPN 393
+ L+E F + + DP KR+TA A + P+ + + +P QL
Sbjct: 1057 RRRLREDF-EFMPAPALDLLDKMLDLDPDKRITAEDALRSPWLRKINPDEMPTPQLP-TW 1114
Query: 394 EECHESDIKRYKSEMNESMSQRPPS 418
++CHE K+ + +M E PP+
Sbjct: 1115 QDCHELWSKKRRRQMREQQESLPPT 1139
>YKL139w [D] KOG0600 Cdc2-related protein kinase
Length = 528
Score = 209 bits (532), Expect = 1e-53
Identities = 122/376 (32%), Positives = 195/376 (51%), Gaps = 49/376 (13%)
Query: 60 KLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNHKNIVKLIE 119
++G+GT+G+V+K + T + VA+K++ ++ E++ FPIT+ REI +L+ +H N+ + E
Sbjct: 188 QVGEGTYGKVYKAKNTNTEKLVALKKLRLQGEREGFPITSIREIKLLQSFDHPNVSTIKE 247
Query: 120 IVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGLLHNPRVE 179
I+ + T +MI Y +DL+GLL N V+
Sbjct: 248 IMVESQKT------------------------------VYMIFEYADNDLSGLLLNKEVQ 277
Query: 180 FGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLARNYYGSPPN 239
+ K++ QLL G+ Y+H NK LHRD+K +NILID++G +KI DFGLAR
Sbjct: 278 ISHSQCKHLFKQLLLGMEYLHDNKILHRDVKGSNILIDNQGNLKITDFGLARKM------ 331
Query: 240 LKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFEKKPILQGQ 299
S A YT+ V+T WYR PE++LG +Y T VD+WG GC+ E F K I QG
Sbjct: 332 -------NSRADYTNRVITLWYRPPELLLGTTNYGTEVDMWGCGCLLVELFNKTAIFQGS 384
Query: 300 TDIDQGHVIFKLMGTPSMDEWGLAYHLPGSEL----TKTNYKSTLQERFSKAL-NETGXX 354
+++Q IFK+MGTP+++ W Y +P + T Y + E+F L +
Sbjct: 385 NELEQIESIFKIMGTPTINSWPTLYDMPWFFMIMPQQTTKYVNNFSEKFKSVLPSSKCLQ 444
Query: 355 XXXXXXXXDPYKRVTAMKAKKHPFFFEEPLPNAQLTLPNEECHESDIKRYKSEMNES-MS 413
D KR +A +A + +F EEP P + CHE ++K + + + +S
Sbjct: 445 LAINLLCYDQTKRFSATEALQSDYFKEEPKPEPLVLDGLVSCHEYEVKLARKQKRPNILS 504
Query: 414 QRPPSAPTGHTSTDNS 429
+ G+++ +N+
Sbjct: 505 TNTNNKGNGNSNNNNN 520
>CE18824 [D] KOG0669 Cyclin T-dependent kinase CDK9
Length = 456
Score = 209 bits (531), Expect = 1e-53
Identities = 128/390 (32%), Positives = 197/390 (49%), Gaps = 69/390 (17%)
Query: 42 NEKVYGVTKFLNNYREEEKLGQGTFG-----------EVFKGIHLGTNRKVAIKRILVRA 90
++ Y + ++ Y + K+GQGTFG EVFK T R VA+K+IL+
Sbjct: 72 DQATYPFIRDVSTYEKLNKIGQGTFGQVLQGRKSRNSEVFKARCKNTGRMVALKKILMEN 131
Query: 91 EKDLFPITAQREITILKRMNHKNIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQ 150
EK+ FPITA RE+ +L+++ H NI LIE+ S + G + A
Sbjct: 132 EKEGFPITALREVKMLEQLKHPNITDLIEVC------------SAKSTGTTGSKDRAT-- 177
Query: 151 KLITGKHFFMILPYMVSDLTGLLHNPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIK 210
F++++ DL GLL NP++ + +K +M L+ G+N +H +K LHRD+K
Sbjct: 178 -------FYLVMALCAHDLAGLLSNPKIRMSLVHIKTMMKHLMSGLNKLHRSKILHRDMK 230
Query: 211 TANILIDHKGVVKIADFGLARNYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGD 270
AN+LI G++K+ADFGLAR P ++ GAG YT+ VVT WYR PE++LGD
Sbjct: 231 AANVLISKDGILKLADFGLAR------PFVQRENGAGPRPLYTNRVVTLWYRPPELLLGD 284
Query: 271 RHYTTAVDIWGIGCVFAEFFEKKPILQGQTDIDQGHVIFKLMGTPSMDEWGLAYHL---- 326
R Y T +D+WG GC+ AE + ++PI+QG T+ Q +I L G+ + D W ++
Sbjct: 285 RQYGTKIDVWGAGCIMAEMWTRQPIMQGDTEQKQLQLISGLCGSINKDVWPNCVNMPLWS 344
Query: 327 -----PGSELTKTNYK---------------STLQERFSK-------ALNETGXXXXXXX 359
P S L + Y+ + + F K A ++
Sbjct: 345 AMSSEPNSALPQGKYRILPNKMKNLMKFDAPDSKTDPFGKNVKQHDSATDDDALHLLEIL 404
Query: 360 XXXDPYKRVTAMKAKKHPFFFEEPLPNAQL 389
DP KR T+ +A+ +FF++P+P A +
Sbjct: 405 LAIDPDKRPTSDEAEDDIWFFKDPVPMANV 434
>Hs7706549 [D] KOG0600 Cdc2-related protein kinase
Length = 1490
Score = 207 bits (526), Expect = 5e-53
Identities = 133/395 (33%), Positives = 201/395 (50%), Gaps = 43/395 (10%)
Query: 61 LGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNHKNIVKLIEI 120
+G+GT+G+V+K T VA+K++ + EK+ FPITA REI IL+++ H+++V + EI
Sbjct: 733 IGEGTYGQVYKARDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQLIHRSVVNMKEI 792
Query: 121 VYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGLLHNPRVEF 180
V D K D+ ++ + A F+++ YM DL GLL + V F
Sbjct: 793 VTD-----KQDAL------DFKKDKGA----------FYLVFEYMDHDLMGLLESGLVHF 831
Query: 181 GMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLARNYYGSPPNL 240
+K+ M QL+EG+ Y H FLHRDIK +NIL+++ G +K+ADFGLAR Y
Sbjct: 832 SEDHIKSFMKQLMEGLEYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLY------- 884
Query: 241 KYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFEKKPILQGQT 300
+ YT+ V+T WYR PE++LG+ YT A+D+W GC+ E F KKPI Q
Sbjct: 885 ----NSEESRPYTNKVITLWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANL 940
Query: 301 DIDQGHVIFKLMGTPSMDEWGLAYHLP--GSELTKTNYKSTLQERFSKALNETGXXXXXX 358
++ Q +I +L G+P W LP + K Y+ L+E FS +
Sbjct: 941 ELAQLELISRLCGSPCPAVWPDVIKLPYFNTMKPKKQYRRRLREEFS-FIPSAALDLLDH 999
Query: 359 XXXXDPYKRVTAMKAKKHPFFFEEPLPN-AQLTLPN-EECHES-DIKRYKSEMNESMSQR 415
DP KR TA + + F + L A LP+ ++CHE KR + + + +
Sbjct: 1000 MLTLDPSKRCTAEQTLQSDFLKDVELSKMAPPDLPHWQDCHELWSKKRRRQRQSGVVVEE 1059
Query: 416 PPSAPTGHTSTDNSIRAVTGAAFPKEASIPKAPRP 450
PP + T T + + P + S P P+P
Sbjct: 1060 PPPSKTSRKETTSGT-----STEPVKNSSPAPPQP 1089
>CE01761 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 719
Score = 202 bits (514), Expect = 1e-51
Identities = 148/413 (35%), Positives = 212/413 (50%), Gaps = 69/413 (16%)
Query: 52 LNNYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREIT-ILKRMN 110
++ Y ++ +GTFG V++G T+ VA+KR+ + EK+ FPITA REI +LK N
Sbjct: 353 IDEYECVNRVDEGTFGVVYRGKDKRTDEIVALKRLKMEKEKEGFPITALREINMLLKAGN 412
Query: 111 HKNIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLT 170
H NIV + EI+ +N K+ +M + ++ D+
Sbjct: 413 HPNIVNVKEILLG-----------------------SNMDKI------YMAMEFVEHDMK 443
Query: 171 GLL---HNPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADF 227
LL F + + K ++ QLL GI ++H LHRD+KT+N+L+ HKG++KIADF
Sbjct: 444 SLLDTMSRRNKRFSIGEQKTLLQQLLSGIEHMHKLWILHRDLKTSNLLMSHKGILKIADF 503
Query: 228 GLARNYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFA 287
GLAR YG P LK K+TS+VVT WYR+PE++LG R Y+T VD+W +GC+ A
Sbjct: 504 GLARE-YGDP--LK---------KFTSIVVTLWYRSPELLLGTRLYSTPVDMWSVGCIMA 551
Query: 288 EFFEKKPILQGQTDIDQGHVIFKLMGTPSMDEWGLAYHLPG-SELTKTNYK-STLQERF- 344
EF KP+ G+ +++Q IF MGTP+ W L G LT Y + L++RF
Sbjct: 552 EFILLKPLFPGRGELEQIKKIFMEMGTPTESIWPGVTELDGWKALTFEKYPYNQLRKRFL 611
Query: 345 -SKALNETGXXXXXXXXXXDPYKRVTAMKAKKHPFFFEEPLPNAQLTLPNEECHESDIKR 403
+ LN+TG DP R +A +A H +F EEP P +P EE
Sbjct: 612 AGRLLNDTGFKLLNGLLTLDPKNRFSATQALDHEWFTEEPYP-----VPPEEFPTFPA-- 664
Query: 404 YKSEMNESMSQRPPSAPTGHTSTDNSIRAVTGAAFPKEASIPK--APRPEHIK 454
KSE N++ PP P +N I V P+ A + K RPE +K
Sbjct: 665 -KSEQNKA----PP--PAKQKQQENRISHVD----PETAKLLKQFEVRPEQVK 706
>Hs4557439 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 305
Score = 200 bits (508), Expect = 6e-51
Identities = 116/339 (34%), Positives = 182/339 (53%), Gaps = 45/339 (13%)
Query: 52 LNNYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNH 111
++ +++ EK+G+GT+G V+K + T + VA+K+I + E + P TA REI++LK + H
Sbjct: 1 MDMFQKVEKIGEGTYGVVYKAKNRETGQLVALKKIRLDLEMEGVPSTAIREISLLKELKH 60
Query: 112 KNIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTG 171
NIV+L+++V++E + +++ ++ DL
Sbjct: 61 PNIVRLLDVVHNE-------------------------------RKLYLVFEFLSQDLKK 89
Query: 172 LLHN-PRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLA 230
+ + P E + +K+ + QLL+G+++ H ++ +HRD+K N+LI+ G +K+ADFGLA
Sbjct: 90 YMDSTPGSELPLHLIKSYLFQLLQGVSFCHSHRVIHRDLKPQNLLINELGAIKLADFGLA 149
Query: 231 RNYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFF 290
R + G P YT VVT WYRAPEI+LG + YTTAVDIW IGC+FAE
Sbjct: 150 RAF-GVPLRT-----------YTHEVVTLWYRAPEILLGSKFYTTAVDIWSIGCIFAEMV 197
Query: 291 EKKPILQGQTDIDQGHVIFKLMGTPSMDEWGLAYHLPGSELTKTNYKSTLQERFSKALNE 350
+K + G ++IDQ IF+++GTPS D W LP + + + E L
Sbjct: 198 TRKALFPGDSEIDQLFRIFRMLGTPSEDTWPGVTQLPDYKGSFPKWTRKGLEEIVPNLEP 257
Query: 351 TGXXXXXXXXXXDPYKRVTAMKAKKHPFFFE-EPLPNAQ 388
G DP +R+TA A HP+F EP P A+
Sbjct: 258 EGRDLLMQLLQYDPSQRITAKTALAHPYFSSPEPSPAAR 296
>7296346 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 952
Score = 200 bits (508), Expect = 6e-51
Identities = 131/370 (35%), Positives = 197/370 (52%), Gaps = 57/370 (15%)
Query: 60 KLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNHKNIVKLIE 119
++ +GT+G V++ TN VA+KR+ + EK+ FPIT+ REI L + H NIV + E
Sbjct: 563 RIEEGTYGVVYRAKDKRTNEIVALKRLKMEKEKEGFPITSLREINTLLKGQHPNIVTVRE 622
Query: 120 IVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGLLH---NP 176
IV VG +N K+ F+++ Y+ DL L+ N
Sbjct: 623 IV----------------VG-------SNMDKI------FIVMDYVEHDLKSLMETMKNR 653
Query: 177 RVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLARNYYGS 236
+ F +VK + QLL + ++H N LHRD+KT+N+L+ HKG++K+ DFGLAR YGS
Sbjct: 654 KQSFFPGEVKCLTQQLLRAVAHLHDNWILHRDLKTSNLLLSHKGILKVGDFGLARE-YGS 712
Query: 237 PPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFEKKPIL 296
P KYTS+VVT WYRAPE++L Y+T +D+W +GC+FAEF + P+
Sbjct: 713 PIK-----------KYTSLVVTLWYRAPELLLCSPVYSTPIDVWSVGCIFAEFLQMLPLF 761
Query: 297 QGQTDIDQGHVIFKLMGTPSMDEWGLAYHLP--------GSELTKTNYKSTLQERFSKAL 348
G+++ID+ + IFK +GTP+ W LP S+ T+ S L++ F +
Sbjct: 762 PGKSEIDELNRIFKELGTPNEKIWPGYTELPAVKNMLSQNSQFTEYPV-SQLRKHFQEKT 820
Query: 349 NETGXXXXXXXXXXDPYKRVTAMKAKKHPFFFEEPLPNAQLTLPNEECHESDIKRYKSEM 408
+E G DP +R++A A KH FF E PLP P +S++ K+
Sbjct: 821 SEMGLSLLQGLLTYDPKQRLSADAALKHGFFKELPLPIDPSMFPTWPA-KSELGARKA-- 877
Query: 409 NESMSQRPPS 418
++ S +PPS
Sbjct: 878 -QASSPKPPS 886
>Hs14110390 [D] KOG0600 Cdc2-related protein kinase
Length = 1452
Score = 199 bits (507), Expect = 8e-51
Identities = 135/426 (31%), Positives = 210/426 (48%), Gaps = 56/426 (13%)
Query: 61 LGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNHKNIVKLIEI 120
+G+GT+G+V+K T VA+K++ + EK+ FPITA REI IL+++ H++I+ + EI
Sbjct: 711 IGEGTYGQVYKARDKDTGEMVALKKVRLDNEKEGFPITAIREIKILRQLTHQSIINMKEI 770
Query: 121 VYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGLLHNPRVEF 180
V D K D+ ++ + A F+++ YM DL GLL + V F
Sbjct: 771 VTD-----KEDAL------DFKKDKGA----------FYLVFEYMDHDLMGLLESGLVHF 809
Query: 181 GMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLARNYYGSPPNL 240
+K+ M QL+EG++Y H FLHRDIK +NIL++++G +K+ADFGLAR Y
Sbjct: 810 NENHIKSFMRQLMEGLDYCHKKNFLHRDIKCSNILLNNRGQIKLADFGLARLY------- 862
Query: 241 KYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFEKKPILQGQT 300
+ YT+ V+T WYR PE++LG+ YT A+D+W GC+ E F KKPI Q
Sbjct: 863 ----SSEESRPYTNKVITLWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANQ 918
Query: 301 DIDQGHVIFKLMGTPSMDEWGLAYHLP--GSELTKTNYKSTLQERFSKALNETGXXXXXX 358
++ Q +I ++ G+P W LP + K Y+ L+E F +
Sbjct: 919 ELAQLELISRICGSPCPAVWPDVIKLPYFNTMKPKKQYRRKLREEF-VFIPAAALDLFDY 977
Query: 359 XXXXDPYKRVTAMKAKKHPFFFE-EPLPNAQLTLPN-EECHE------------------ 398
DP KR TA +A + F + EP LP ++CHE
Sbjct: 978 MLALDPSKRCTAEQALQCEFLRDVEPSKMPPPDLPLWQDCHELWSKKRRRQKQMGMTDDV 1037
Query: 399 SDIKRYKSEMNESMSQRPPSAPTG-HTSTDNSIRAVTGAAFPKEASIPKAPRPEHIKSTI 457
S IK + +++ + + P G S+ + + A ++ + P P+ E K
Sbjct: 1038 STIKAPRKDLSLGLDDSRTNTPQGVLPSSQLKSQGSSNVAPGEKQTDPSTPQQESSKPLG 1097
Query: 458 PAQPSA 463
QPS+
Sbjct: 1098 GIQPSS 1103
>Hs14110387 [D] KOG0600 Cdc2-related protein kinase
Length = 1512
Score = 199 bits (506), Expect = 1e-50
Identities = 123/357 (34%), Positives = 188/357 (52%), Gaps = 37/357 (10%)
Query: 61 LGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNHKNIVKLIEI 120
+G+GT+G+V+K T VA+K++ + EK+ FPITA REI IL+++ H++I+ + EI
Sbjct: 711 IGEGTYGQVYKARDKDTGEMVALKKVRLDNEKEGFPITAIREIKILRQLTHQSIINMKEI 770
Query: 121 VYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGLLHNPRVEF 180
V D K D+ ++ + A F+++ YM DL GLL + V F
Sbjct: 771 VTD-----KEDAL------DFKKDKGA----------FYLVFEYMDHDLMGLLESGLVHF 809
Query: 181 GMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLARNYYGSPPNL 240
+K+ M QL+EG++Y H FLHRDIK +NIL++++G +K+ADFGLAR Y
Sbjct: 810 NENHIKSFMRQLMEGLDYCHKKNFLHRDIKCSNILLNNRGQIKLADFGLARLY------- 862
Query: 241 KYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFEKKPILQGQT 300
+ YT+ V+T WYR PE++LG+ YT A+D+W GC+ E F KKPI Q
Sbjct: 863 ----SSEESRPYTNKVITLWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANQ 918
Query: 301 DIDQGHVIFKLMGTPSMDEWGLAYHLP--GSELTKTNYKSTLQERFSKALNETGXXXXXX 358
++ Q +I ++ G+P W LP + K Y+ L+E F +
Sbjct: 919 ELAQLELISRICGSPCPAVWPDVIKLPYFNTMKPKKQYRRKLREEF-VFIPAAALDLFDY 977
Query: 359 XXXXDPYKRVTAMKAKKHPFFFE-EPLPNAQLTLPN-EECHESDIKRYKSEMNESMS 413
DP KR TA +A + F + EP LP ++CHE K+ + + M+
Sbjct: 978 MLALDPSKRCTAEQALQCEFLRDVEPSKMPPPDLPLWQDCHELWSKKRRRQKQMGMT 1034
>Hs4502731 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 360
Score = 198 bits (504), Expect = 2e-50
Identities = 128/371 (34%), Positives = 190/371 (50%), Gaps = 46/371 (12%)
Query: 47 GVTKFLNNYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITIL 106
G + + + + ++G+GT+G V++ T+ VA+K++ + EKD PI++ REIT+L
Sbjct: 31 GRCRSVKEFEKLNRIGEGTYGIVYRARDTQTDEIVALKKVRMDKEKDGIPISSLREITLL 90
Query: 107 KRMNHKNIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMV 166
R+ H NIV+L E+V VGN+ + F+++ Y
Sbjct: 91 LRLRHPNIVELKEVV----------------VGNHL-------------ESIFLVMGYCE 121
Query: 167 SDLTGLLHNPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIAD 226
DL LL N F A VK I+LQ+L G+ Y+H N +HRD+K +N+L+ KG VK AD
Sbjct: 122 QDLASLLENMPTPFSEAQVKCIVLQVLRGLQYLHRNFIIHRDLKVSNLLMTDKGCVKTAD 181
Query: 227 FGLARNYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVF 286
FGLAR YG P T VVT WYRAPE++LG TT++D+W +GC+
Sbjct: 182 FGLAR-AYGVPVK-----------PMTPKVVTLWYRAPELLLGTTTQTTSIDMWAVGCIL 229
Query: 287 AEFFEKKPILQGQTDIDQGHVIFKLMGTPSMDEWGLAYHLP--GSELTKTNYKSTLQERF 344
AE +P+L G ++I Q +I +L+GTPS + W LP G + + L+ +F
Sbjct: 230 AELLAHRPLLPGTSEIHQIDLIVQLLGTPSENIWPGFSKLPLVGQYSLRKQPYNNLKHKF 289
Query: 345 SKALNETGXXXXXXXXXXDPYKRVTAMKAKKHPFFFEEPLPNAQLTLPNEECHESDIKRY 404
L+E G DP KR TA + +F E+PLP +P H + KR
Sbjct: 290 -PWLSEAGLRLLHFLFMYDPKKRATAGDCLESSYFKEKPLPCEPELMPTFPHHRN--KRA 346
Query: 405 KSEMNESMSQR 415
+E S+R
Sbjct: 347 APATSEGQSKR 357
>At3g48750 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 294
Score = 198 bits (503), Expect = 2e-50
Identities = 117/330 (35%), Positives = 169/330 (50%), Gaps = 45/330 (13%)
Query: 52 LNNYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNH 111
++ Y + EK+G+GT+G V+K TN +A+K+I + E + P TA REI++LK M H
Sbjct: 1 MDQYEKVEKIGEGTYGVVYKARDKVTNETIALKKIRLEQEDEGVPSTAIREISLLKEMQH 60
Query: 112 KNIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTG 171
NIVK ++V+ E K +++ Y+ DL
Sbjct: 61 SNIVKYDDVVHSE-------------------------------KRLYLVFEYLDLDLKK 89
Query: 172 LLHN-PRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHK-GVVKIADFGL 229
+ + P + +K + Q+L GI Y H ++ LHRD+K N+LID + +K+ADFGL
Sbjct: 90 HMDSTPDFSKDLHMIKTYLYQILRGIAYCHSHRVLHRDLKPQNLLIDRRTNSLKLADFGL 149
Query: 230 ARNYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEF 289
AR + G P +T VVT WYRAPEI+LG HY+T VDIW +GC+FAE
Sbjct: 150 ARAF-GIPVRT-----------FTHEVVTLWYRAPEILLGSHHYSTPVDIWSVGCIFAEM 197
Query: 290 FEKKPILQGQTDIDQGHVIFKLMGTPSMDEWGLAYHLPGSELTKTNYKSTLQERFSKALN 349
+KP+ G ++IDQ IF++MGTP D W LP + +K T E F L+
Sbjct: 198 ISQKPLFPGDSEIDQLFKIFRIMGTPYEDTWRGVTSLPDYKSAFPKWKPTDLETFVPNLD 257
Query: 350 ETGXXXXXXXXXXDPYKRVTAMKAKKHPFF 379
G DP KR+ A A +H +F
Sbjct: 258 PDGVDLLSKMLLMDPTKRINARAALEHEYF 287
>At1g74330 [D] KOG0600 Cdc2-related protein kinase
Length = 445
Score = 196 bits (498), Expect = 9e-50
Identities = 126/343 (36%), Positives = 180/343 (51%), Gaps = 48/343 (13%)
Query: 55 YREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNHKNI 114
+ + EK+GQGT+ VF+ + T R VA+K++ + REI IL+R+NH NI
Sbjct: 121 FEKLEKIGQGTYSNVFRAVETETGRIVALKKVRFDNFEPESVKFMAREILILRRLNHPNI 180
Query: 115 VKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGK---HFFMILPYMVSDLTG 171
+KL + LIT K + ++ YM DLTG
Sbjct: 181 IKL--------------------------------EGLITSKLSCNIQLVFEYMEHDLTG 208
Query: 172 LLHNPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLAR 231
LL +P ++F +K M QLL G+++ H +HRDIK +N+L+ ++G++K+ADFGLA
Sbjct: 209 LLSSPDIKFTTPQIKCYMKQLLSGLDHCHSRGVMHRDIKGSNLLLSNEGILKVADFGLA- 267
Query: 232 NYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFE 291
N+ S + K P TS VVT WYR PE++LG Y +VD+W +GCVFAE
Sbjct: 268 NFSNSSGHKKKP--------LTSRVVTLWYRPPELLLGATDYGASVDLWSVGCVFAELLL 319
Query: 292 KKPILQGQTDIDQGHVIFKLMGTPSMDEWGLAYHLPGSELTK--TNYKSTLQERFSKALN 349
KPIL+G+T+++Q H IFKL G+P D W + LP + L K Y S L+E K L+
Sbjct: 320 GKPILRGRTEVEQLHKIFKLCGSPPEDYWKKS-KLPHAMLFKPQQTYDSCLRETL-KDLS 377
Query: 350 ETGXXXXXXXXXXDPYKRVTAMKAKKHPFFFEEPLPNAQLTLP 392
ET DP+KR TA A +F +P +LP
Sbjct: 378 ETEINLIETLLSIDPHKRGTASSALVSQYFTTKPFACDPSSLP 420
>Hs4502709 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 297
Score = 195 bits (496), Expect = 2e-49
Identities = 115/330 (34%), Positives = 172/330 (51%), Gaps = 45/330 (13%)
Query: 52 LNNYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNH 111
+ +Y + EK+G+GT+G V+KG H T + VA+K+I + +E++ P TA REI++LK + H
Sbjct: 1 MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRH 60
Query: 112 KNIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTG 171
NIV L +++ +S ++I ++ DL
Sbjct: 61 PNIVSLQDVLMQDS-------------------------------RLYLIFEFLSMDLKK 89
Query: 172 LLHN--PRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGL 229
L + P + VK+ + Q+L+GI + H + LHRD+K N+LID KG +K+ADFGL
Sbjct: 90 YLDSIPPGQYMDSSLVKSYLYQILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGL 149
Query: 230 ARNYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEF 289
AR + G P + YT VVT WYR+PE++LG Y+T VDIW IG +FAE
Sbjct: 150 ARAF-GIPIRV-----------YTHEVVTLWYRSPEVLLGSARYSTPVDIWSIGTIFAEL 197
Query: 290 FEKKPILQGQTDIDQGHVIFKLMGTPSMDEWGLAYHLPGSELTKTNYKSTLQERFSKALN 349
KKP+ G ++IDQ IF+ +GTP+ + W L + T +K K L+
Sbjct: 198 ATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNTFPKWKPGSLASHVKNLD 257
Query: 350 ETGXXXXXXXXXXDPYKRVTAMKAKKHPFF 379
E G DP KR++ A HP+F
Sbjct: 258 ENGLDLLSKMLIYDPAKRISGKMALNHPYF 287
>At5g63370 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 612
Score = 195 bits (496), Expect = 2e-49
Identities = 115/356 (32%), Positives = 192/356 (53%), Gaps = 52/356 (14%)
Query: 49 TKFLNNYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRA----EKDLFPITAQREIT 104
++ +N +++ K+ +GT+G V+K T VA+K+I ++ E+ FP+T+ REI
Sbjct: 291 SRSVNEFQKLNKINEGTYGIVYKARDEKTKEIVALKKIKMKEDRFEEEYGFPLTSLREIN 350
Query: 105 ILKRMNHKNIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPY 164
IL NH IV + E+V VG + N+ +M++ +
Sbjct: 351 ILLSCNHPAIVNVKEVV----------------VGGKNDNDV------------YMVMEH 382
Query: 165 MVSDLTGLLHNPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKI 224
+ DL G++ + F ++VK +M+QLL+G+ Y+H N +HRD+K +N+L+++ G +KI
Sbjct: 383 LEHDLRGVMDRRKEPFSTSEVKCLMMQLLDGLKYLHTNWIIHRDLKPSNLLMNNCGELKI 442
Query: 225 ADFGLARNYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGC 284
DFG+AR Y GSP YT +V+T+WYR PE++LG + Y+TAVD+W +GC
Sbjct: 443 CDFGMARQY-GSPIK-----------PYTQMVITQWYRPPELLLGAKEYSTAVDMWSVGC 490
Query: 285 VFAEFFEKKPILQGQTDIDQGHVIFKLMGTPSMDEWGLAYHLPGSELT-KTNYKSTLQER 343
+ AE +KP+ G++++DQ IF ++GTP+ W P ++ T + L+++
Sbjct: 491 IMAELLSQKPLFPGKSELDQLQKIFAVLGTPNEAIWPGFSSFPNAKAKFPTQPYNMLRKK 550
Query: 344 F-------SKALNETGXXXXXXXXXXDPYKRVTAMKAKKHPFFFEEPLPNAQLTLP 392
F + L+E G DP KR+T A H +F E PLP ++ +P
Sbjct: 551 FPAISFVGGQILSERGFDLLNSLLTLDPEKRLTVEDALNHGWFHEVPLPKSKDFMP 606
>Hs16936528 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 298
Score = 195 bits (495), Expect = 2e-49
Identities = 115/344 (33%), Positives = 186/344 (53%), Gaps = 52/344 (15%)
Query: 52 LNNYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNH 111
+ N+++ EK+G+GT+G V+K + T VA+K+I + E + P TA REI++LK +NH
Sbjct: 1 MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNH 60
Query: 112 KNIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTG 171
NIVKL+++++ E+ +++ ++ DL
Sbjct: 61 PNIVKLLDVIHTENK-------------------------------LYLVFEFLHQDLKK 89
Query: 172 LLHNPRVE-FGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLA 230
+ + + +K+ + QLL+G+ + H ++ LHRD+K N+LI+ +G +K+ADFGLA
Sbjct: 90 FMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLA 149
Query: 231 RNYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFF 290
R + G P YT VVT WYRAPEI+LG ++Y+TAVDIW +GC+FAE
Sbjct: 150 RAF-GVPVRT-----------YTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMV 197
Query: 291 EKKPILQGQTDIDQGHVIFKLMGTPSMDEWGLAYHLPGSELTKTNYKSTLQERFSKA--- 347
++ + G ++IDQ IF+ +GTP W +P K ++ ++ FSK
Sbjct: 198 TRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPD---YKPSFPKWARQDFSKVVPP 254
Query: 348 LNETGXXXXXXXXXXDPYKRVTAMKAKKHPFFFE--EPLPNAQL 389
L+E G DP KR++A A HPFF + +P+P+ +L
Sbjct: 255 LDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL 298
>Hs16950647 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 314
Score = 192 bits (488), Expect = 1e-48
Identities = 120/340 (35%), Positives = 178/340 (52%), Gaps = 44/340 (12%)
Query: 47 GVTKFLNNYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITIL 106
G + + + + ++G+GT+G V++ T+ VA+K++ + EKD PI++ REIT+L
Sbjct: 2 GRCRSVKEFEKLNRIGEGTYGIVYRARDTQTDEIVALKKVRMDKEKDGIPISSLREITLL 61
Query: 107 KRMNHKNIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMV 166
R+ H NIV+L E+V VGN+ + F+++ Y
Sbjct: 62 LRLRHPNIVELKEVV----------------VGNHL-------------ESIFLVMGYCE 92
Query: 167 SDLTGLLHNPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIAD 226
DL LL N F A VK I+LQ+L G+ Y+H N +HRD+K +N+L+ KG VK AD
Sbjct: 93 QDLASLLENMPTPFSEAQVKCIVLQVLRGLQYLHRNFIIHRDLKVSNLLMTDKGCVKTAD 152
Query: 227 FGLARNYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVF 286
FGLAR YG P T VVT WYRAPE++LG TT++D+W +GC+
Sbjct: 153 FGLAR-AYGVPVK-----------PMTPKVVTLWYRAPELLLGTTTQTTSIDMWAVGCIL 200
Query: 287 AEFFEKKPILQGQTDIDQGHVIFKLMGTPSMDEWGLAYHLP--GSELTKTNYKSTLQERF 344
AE +P+L G ++I Q +I +L+GTPS + W LP G + + L+ +F
Sbjct: 201 AELLAHRPLLPGTSEIHQIDLIVQLLGTPSENIWPGFSKLPLVGQYSLRKQPYNNLKHKF 260
Query: 345 SKALNETGXXXXXXXXXXDPYKRVTAMKAKKHPFFFEEPL 384
L+E G DP KR TA + +F E+PL
Sbjct: 261 -PWLSEAGLRLLHFLFMYDPKKRATAGDCLESSYFKEKPL 299
>At1g18670 [D] KOG0600 Cdc2-related protein kinase
Length = 662
Score = 192 bits (488), Expect = 1e-48
Identities = 123/354 (34%), Positives = 182/354 (50%), Gaps = 44/354 (12%)
Query: 43 EKVYGVTKFLNNYREE-EKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQR 101
E ++G F ++ E+ EK+GQGT+ VF+ T R VA+K++ + R
Sbjct: 118 EAIHGWVPFRSDAFEKLEKIGQGTYSSVFRARETETGRIVALKKVRFDNFEPESVRFMAR 177
Query: 102 EITILKRMNHKNIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMI 161
EI IL+++NH NI+KL IV KL H ++
Sbjct: 178 EILILRKLNHPNIIKLEGIV---------------------------TSKLSCSIH--LV 208
Query: 162 LPYMVSDLTGLLHNPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGV 221
YM DLTGLL +P ++F +K M QLL G+++ H +HRDIK +N+L++++G+
Sbjct: 209 FEYMEHDLTGLLSSPDIDFTTPQIKCYMKQLLSGLDHCHARGVMHRDIKGSNLLVNNEGI 268
Query: 222 VKIADFGLARNYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWG 281
+K+ADFGLA + +G+ TS VVT WYR PE++LG Y +VD+W
Sbjct: 269 LKVADFGLAN----------FCNASGNKQPLTSRVVTLWYRPPELLLGATEYGASVDLWS 318
Query: 282 IGCVFAEFFEKKPILQGQTDIDQGHVIFKLMGTPSMDEWGLAYHLPGSELTK--TNYKST 339
+GCVFAE KP+LQG+T+++Q H IFKL G+P D W + LP + L K +Y
Sbjct: 319 VGCVFAELLIGKPVLQGRTEVEQLHKIFKLCGSPPEDYWKKS-KLPHAMLFKPQQHYDGC 377
Query: 340 LQERFS-KALNETGXXXXXXXXXXDPYKRVTAMKAKKHPFFFEEPLPNAQLTLP 392
L+E K L++ P+KR TA A +F +P +LP
Sbjct: 378 LRETLKLKGLSDADINLIETLLSIQPHKRGTASTALVSQYFTSKPFACDPSSLP 431
>At1g09600 [D] KOG0600 Cdc2-related protein kinase
Length = 714
Score = 191 bits (484), Expect = 4e-48
Identities = 124/359 (34%), Positives = 181/359 (49%), Gaps = 47/359 (13%)
Query: 53 NNYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRI-LVRAEKDLFPITAQREITILKRMNH 111
+++ + EK+GQGT+ V+K L TN+ VA+K++ + D A REI IL+R++H
Sbjct: 161 DSFEKLEKIGQGTYSSVYKARDLETNQLVALKKVRFANMDPDSVRFMA-REIIILRRLDH 219
Query: 112 KNIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTG 171
N++KL ++ ++G ++I YM DL G
Sbjct: 220 PNVMKLEGLITSR----------------------------VSGS-MYLIFEYMEHDLAG 250
Query: 172 LLHNPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLAR 231
L P + F A +K M QLL G+ + H LHRDIK +N+L+DH +KI DFGLA
Sbjct: 251 LASTPGINFSEAQIKCYMKQLLHGLEHCHSRGVLHRDIKGSNLLLDHNNNLKIGDFGLAN 310
Query: 232 NYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFE 291
Y G + K P TS VVT WYR PE++LG Y VD+W GC+ AE F
Sbjct: 311 FYQG---HQKQP--------LTSRVVTLWYRPPELLLGSTDYGVTVDLWSTGCILAELFT 359
Query: 292 KKPILQGQTDIDQGHVIFKLMGTPSMDEWGLAYHLPGSELTKTN--YKSTLQERFSKALN 349
KPI+ G+T+++Q H IFKL G+PS + W ++ LP + + K YK + E F K+L
Sbjct: 360 GKPIMPGRTEVEQLHKIFKLCGSPSEEYWKIS-KLPHATIFKPQQPYKRCVAETF-KSLP 417
Query: 350 ETGXXXXXXXXXXDPYKRVTAMKAKKHPFFFEEPLPNAQLTLPN-EECHESDIKRYKSE 407
+ +P R T A + FF PL + +LP + E D+K + E
Sbjct: 418 SSALALVEVLLAVEPDARGTTASALESEFFTTSPLASDPSSLPKYQPRKEIDVKAQEEE 476
>SPBC18H10.15 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 398
Score = 187 bits (476), Expect = 3e-47
Identities = 119/369 (32%), Positives = 186/369 (50%), Gaps = 46/369 (12%)
Query: 52 LNNYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNH 111
+++Y EK+ +G++G V++G+ TN VA+K+I FPIT+ REI L + H
Sbjct: 71 IDDYEILEKIEEGSYGIVYRGLDKSTNTLVALKKIKFDPNGIGFPITSLREIESLSSIRH 130
Query: 112 KNIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTG 171
NIV+L ++V + K ++++ +M DL
Sbjct: 131 DNIVELEKVVVGKDL-----------------------------KDVYLVMEFMEHDLKT 161
Query: 172 LLHNPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLAR 231
LL N +F ++VK +MLQLL ++H + +LHRD+K +N+L+++ G +K+ADFGLAR
Sbjct: 162 LLDNMPEDFLQSEVKTLMLQLLAATAFMHHHWYLHRDLKPSNLLMNNTGEIKLADFGLAR 221
Query: 232 NYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFE 291
S P + T +VVT WYRAPE++LG Y +D+W IGC+FAE
Sbjct: 222 PV--SEPK----------SSLTRLVVTLWYRAPELLLGAPSYGKEIDMWSIGCIFAEMIT 269
Query: 292 KKPILQGQTDIDQGHVIFKLMGTPSMDEWGLAYHLPGSELTKTNYKSTLQERFSKALNET 351
+ P+ G++++DQ + IF L+G P+ +EW + LP + K T + + N T
Sbjct: 270 RTPLFSGKSELDQLYKIFNLLGYPTREEWPQYFLLPYANKIKHPTVPTHSKIRTSIPNLT 329
Query: 352 GXX--XXXXXXXXDPYKRVTAMKAKKHPFFFEEPLPNAQLTLPNEECHESDIKRYKSEMN 409
G +P KR++A +A +HP+F+E P P P S K E N
Sbjct: 330 GNAYDLLNRLLSLNPAKRISAKEALEHPYFYESPRPKDPKFFPT---FPSKAKGESKEKN 386
Query: 410 ESMSQRPPS 418
S R S
Sbjct: 387 VFQSFRSAS 395
>At1g73690 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 398
Score = 187 bits (476), Expect = 3e-47
Identities = 125/401 (31%), Positives = 187/401 (46%), Gaps = 52/401 (12%)
Query: 50 KFLNNYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRM 109
K + Y + E LGQGT+G VFK VAIK+I + EK+ +TA REI +LK +
Sbjct: 6 KVADRYLKREVLGQGTYGVVFKATDTKNGETVAIKKIRLGKEKEGVNVTALREIKLLKEL 65
Query: 110 NHKNIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDL 169
H +I++LI+ + N H ++ +M +DL
Sbjct: 66 KHPHIIELIDAFPHKE--------------NLH-----------------IVFEFMETDL 94
Query: 170 TGLLHNPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGL 229
++ + + DVK+ + +L+G+ Y H LHRD+K N+LI G +K+ADFGL
Sbjct: 95 EAVIRDRNLYLSPGDVKSYLQMILKGLEYCHGKWVLHRDMKPNNLLIGPNGQLKLADFGL 154
Query: 230 ARNYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEF 289
AR +GSP G K+T V RWYRAPE++ G + Y AVD+W GC+FAE
Sbjct: 155 AR-IFGSP-----------GRKFTHQVFARWYRAPELLFGAKQYDGAVDVWAAGCIFAEL 202
Query: 290 FEKKPILQGQTDIDQGHVIFKLMGTPSMDEWGLAYHLPGSELTKTNYKSTLQERFSKALN 349
++P LQG +DIDQ IF GTP D+W LP + +L+ ++
Sbjct: 203 LLRRPFLQGNSDIDQLSKIFAAFGTPKADQWPDMICLPDYVEYQFVPAPSLRS-LLPTVS 261
Query: 350 ETGXXXXXXXXXXDPYKRVTAMKAKKHPFFFEEPLPNAQLTLP----NEECHESDIK--- 402
E DP R++ +A KH +F P P L LP ++ SD K
Sbjct: 262 EDALDLLSKMFTYDPKSRISIQQALKHRYFTSAPSPTDPLKLPRPVSKQDAKSSDSKLEA 321
Query: 403 -RYKSEMNESMSQRPPSAPTGHTSTDNSIRAVTGAAFPKEA 442
+ S ++ P +G+ D S+ + A+ +A
Sbjct: 322 IKVLSPAHKFRRVMPDRGKSGNGFKDQSVDVMRQASHDGQA 362
>SPBC19F8.07 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 335
Score = 187 bits (475), Expect = 4e-47
Identities = 117/355 (32%), Positives = 180/355 (49%), Gaps = 46/355 (12%)
Query: 55 YREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNHKNI 114
Y +E K+G+GT+ VF G TNR+VAIK+I V KD I+A REI L+ H N+
Sbjct: 11 YVKERKVGEGTYAVVFLGRQKETNRRVAIKKIKVGQFKDGIDISALREIKFLRESRHDNV 70
Query: 115 VKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGLLH 174
++L+++ +S + +IL ++ SDL L+
Sbjct: 71 IELVDVFSTKS-------------------------------NLNIILEFLDSDLEMLIK 99
Query: 175 NPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLARNYY 234
+ + F A +K+ M+ LL G+++IH LHRD+K N+LI GV+K+ADFGL+R++
Sbjct: 100 DKFIVFQPAHIKSWMVMLLRGLHHIHSRFILHRDLKPNNLLISSDGVLKLADFGLSRDF- 158
Query: 235 GSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFEKKP 294
G+P ++ + V+TRWYR PE+ +G R Y T VD+W +GC+FAE + P
Sbjct: 159 GTPSHMSHQ------------VITRWYRPPELFMGCRSYGTGVDMWSVGCIFAELMLRTP 206
Query: 295 ILQGQTDIDQGHVIFKLMGTPSMDEWGLAYHLPG-SELTKTNYKSTLQERFSKALNETGX 353
L G++D+DQ +VIF+ +GTP + LP E+ + E A
Sbjct: 207 YLPGESDLDQLNVIFRALGTPEPEVIKSMQQLPNYVEMKHIPPPNGGMEALFSAAGHEEI 266
Query: 354 XXXXXXXXXDPYKRVTAMKAKKHPFFFEEPLPNAQLTLPNEECHESDIKRYKSEM 408
+PY+R TA +A +H +F P P LP + E IK S++
Sbjct: 267 DLLKMMLDYNPYRRPTAQQALEHHYFSALPKPTHPSLLPRKG-GEEGIKHVSSDL 320
>CE03811 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 763
Score = 187 bits (475), Expect = 4e-47
Identities = 119/331 (35%), Positives = 172/331 (51%), Gaps = 44/331 (13%)
Query: 61 LGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREIT-ILKRMNHKNIVKLIE 119
+ +GT+GEVF+G + T+ VA+KR + EK+ FPITA REI +LK H+NIV + E
Sbjct: 405 IAEGTYGEVFRGKNTRTDEVVALKRFKMEKEKEGFPITALREINMLLKAGAHENIVNVKE 464
Query: 120 IVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGLLHNPRVE 179
I+ + T +M + Y+ D+ L+ R
Sbjct: 465 ILVGSTKT-----------------------------EVYMAMEYVEHDVKSLIDKMRSR 495
Query: 180 ---FGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLARNYYGS 236
F K +M QLL GI ++H LHRD+KT+N+LI H G++KIADFGLAR Y G
Sbjct: 496 NQRFKTGQQKTLMSQLLSGIEHMHKLWILHRDLKTSNLLISHSGILKIADFGLAREY-GE 554
Query: 237 PPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFEKKPIL 296
+++ K T +VVT WYR+PE++L + Y+T VD+W IGC+ AEF KP+
Sbjct: 555 ARDIE------KRMKLTPIVVTLWYRSPELLLEPKTYSTPVDMWSIGCIMAEFIMMKPMF 608
Query: 297 QGQTDIDQGHVIFKLMGTPSMDEWGLAYHLPGSELTKTNYKSTLQER----FSKALNETG 352
QG ++ +Q H IF++MGTP+ W L + + Q R K +NETG
Sbjct: 609 QGDSEPNQVHQIFQMMGTPTEQIWPDIKELKVWNMVEFPPVKPGQLRRIFKGEKLVNETG 668
Query: 353 XXXXXXXXXXDPYKRVTAMKAKKHPFFFEEP 383
+P R+TA +A +H +F E P
Sbjct: 669 FDLLNGMLCLNPANRLTASEALQHDWFSEHP 699
>At5g50860 [D] KOG0600 Cdc2-related protein kinase
Length = 580
Score = 187 bits (475), Expect = 4e-47
Identities = 126/367 (34%), Positives = 180/367 (48%), Gaps = 64/367 (17%)
Query: 55 YREEEKLGQGTFGEVFKGIHLGTNRKVAIKRIL---VRAEKDLFPITAQREITILKRMNH 111
Y + EK+GQGT+ V+K L + + VA+K++ + AE F REI +L+R+NH
Sbjct: 114 YEKLEKIGQGTYSNVYKAKDLLSGKIVALKKVRFDNLEAESVKF---MAREILVLRRLNH 170
Query: 112 KNIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGK---HFFMILPYMVSD 168
N++KL Q L+T + +++ YM D
Sbjct: 171 PNVIKL--------------------------------QGLVTSRVSCSLYLVFEYMEHD 198
Query: 169 LTGLLHNPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFG 228
L+GL ++F + VK M QLL G+ + H LHRDIK +N+LID+ G++KIADFG
Sbjct: 199 LSGLAATQGLKFDLPQVKCFMKQLLSGLEHCHSRGVLHRDIKGSNLLIDNDGILKIADFG 258
Query: 229 LARNYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAE 288
LA Y P K TS VVT WYR PE++LG Y T VD+W GC+ AE
Sbjct: 259 LATFY---DPKQKQT--------MTSRVVTLWYRPPELLLGATSYGTGVDLWSAGCIMAE 307
Query: 289 FFEKKPILQGQTDIDQGHVIFKLMGTPSMDEWGLAYHLPGSELTKTN--YKSTLQERFSK 346
KP++ G+T+++Q H IFKL G+PS D + Y LP + L K YK + E F+
Sbjct: 308 LLAGKPVMPGRTEVEQLHKIFKLCGSPS-DSYWKKYRLPNATLFKPQHPYKRCVAEAFN- 365
Query: 347 ALNETGXXXXXXXXXXDPYKRVTAMKAKKHPFFFEEPLPNAQLTLP--------NEECHE 398
+ DP R T+ A FF EPLP +LP N + +
Sbjct: 366 GFTPSSVHLVETLLTIDPADRGTSTSALNSEFFTTEPLPCDPSSLPKYPPSKELNVKLRD 425
Query: 399 SDIKRYK 405
+++R K
Sbjct: 426 EELRRQK 432
>At1g54610 [D] KOG0600 Cdc2-related protein kinase
Length = 572
Score = 186 bits (471), Expect = 1e-46
Identities = 131/398 (32%), Positives = 191/398 (47%), Gaps = 54/398 (13%)
Query: 48 VTKFLNNYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILV-RAEKDLFPITAQREITIL 106
V + + + + +K+GQGT+ V+K + T + VA+K++ E + A REI +L
Sbjct: 111 VPRKADTFEKIDKIGQGTYSNVYKAKDMLTGKIVALKKVRFDNLEPESVKFMA-REILVL 169
Query: 107 KRMNHKNIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGK---HFFMILP 163
+R++H N+VKL + L+T + +++
Sbjct: 170 RRLDHPNVVKL--------------------------------EGLVTSRMSCSLYLVFQ 197
Query: 164 YMVSDLTGLLHNPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVK 223
YM DL GL +P V+F ++VK +M QL+ G+ + H LHRDIK +N+LID GV+K
Sbjct: 198 YMDHDLAGLASSPVVKFSESEVKCLMRQLISGLEHCHSRGVLHRDIKGSNLLIDDGGVLK 257
Query: 224 IADFGLARNYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIG 283
IADFGLA + PN K P TS VVT WYRAPE++LG Y +D+W G
Sbjct: 258 IADFGLATIF---DPNHKRP--------MTSRVVTLWYRAPELLLGATDYGVGIDLWSAG 306
Query: 284 CVFAEFFEKKPILQGQTDIDQGHVIFKLMGTPSMDEWGLAYHLPGS-ELTKTNYKSTLQE 342
C+ AE +PI+ G+T+++Q H I+KL G+PS D W G+ + YK +++E
Sbjct: 307 CILAELLAGRPIMPGRTEVEQLHKIYKLCGSPSEDYWKKGKFTHGAIYKPREPYKRSIRE 366
Query: 343 RFSKALNETGXXXXXXXXXXDPYKRVTAMKAKKHPFFFEEPLPNAQLTLPN-EECHESDI 401
F K + +P R TA A K FF EP LP E D
Sbjct: 367 TF-KDFPPSSLPLIDALLSIEPEDRQTASAALKSEFFTSEPYACEPADLPKYPPSKEIDA 425
Query: 402 KRYKSEMNESMSQRPPSAPTGHTSTDNSIRAVTGAAFP 439
KR E+ QR S G + N R + A P
Sbjct: 426 KR---RDEETRRQRAASKAQGDGARKNRHRDRSNRALP 460
>7300650 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 314
Score = 186 bits (471), Expect = 1e-46
Identities = 107/332 (32%), Positives = 168/332 (50%), Gaps = 45/332 (13%)
Query: 48 VTKFLNNYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILK 107
+T L+N++ EK+G+GT+G V+K T + VA+K+I + E + P TA REI++LK
Sbjct: 1 MTTILDNFQRAEKIGEGTYGIVYKARSNSTGQDVALKKIRLEGETEGVPSTAIREISLLK 60
Query: 108 RMNHKNIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVS 167
+ H N+V+L ++V I+G + +MI Y+
Sbjct: 61 NLKHPNVVQLFDVV-------------------------------ISGNNLYMIFEYLNM 89
Query: 168 DLTGLLHNPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADF 227
DL L+ + F +K+ M Q+L+ + + H N+ LHRD+K N+L+D G +K+ADF
Sbjct: 90 DLKKLMDKKKDVFTPQLIKSYMHQILDAVGFCHTNRILHRDLKPQNLLVDTAGKIKLADF 149
Query: 228 GLARNYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFA 287
GLAR + P A YT VVT WYRAPEI+LG + Y+T VDIW +GC+F+
Sbjct: 150 GLARAF-------NVPMRA-----YTHEVVTLWYRAPEILLGTKFYSTGVDIWSLGCIFS 197
Query: 288 EFFEKKPILQGQTDIDQGHVIFKLMGTPSMDEWGLAYHLPGSELTKTNYKSTLQERFSKA 347
E ++ + G ++IDQ + IF+ + TP W LP + ++ T +
Sbjct: 198 EMIMRRSLFPGDSEIDQLYRIFRTLSTPDETNWPGVTQLPDFKTKFPRWEGTNMPQ--PI 255
Query: 348 LNETGXXXXXXXXXXDPYKRVTAMKAKKHPFF 379
DP R++A A +H +F
Sbjct: 256 TEHEAHELIMSMLCYDPNLRISAKDALQHAYF 287
>CE00315 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 332
Score = 185 bits (469), Expect = 2e-46
Identities = 113/350 (32%), Positives = 180/350 (51%), Gaps = 56/350 (16%)
Query: 39 SRENEKVYGVTKFLNNYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPIT 98
+ E + VY LN++ + EK+G+GT+G V+KG + TN VA+K+I + +E + P T
Sbjct: 10 AHEGDSVYT----LNDFTKLEKIGEGTYGVVYKGKNRRTNAMVAMKKIRLESEDEGVPST 65
Query: 99 AQREITILKRMNHKNIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHF 158
A REI++LK + H N+V L ++ E+
Sbjct: 66 AVREISLLKELQHPNVVGLEAVIMQEN-------------------------------RL 94
Query: 159 FMILPYMVSDLTGLLHNPRVE--FGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILI 216
F+I ++ DL + + + +K+ Q+L+ + + H + +HRD+K N+L+
Sbjct: 95 FLIFEFLSFDLKRYMDQLGKDEYLPLETLKSYTFQILQAMCFCHQRRVIHRDLKPQNLLV 154
Query: 217 DHKGVVKIADFGLARNYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTA 276
D+ G +K+ADFGLAR G P + YT VVT WYRAPEI++G + Y+
Sbjct: 155 DNNGAIKLADFGLARAI-GIPIRV-----------YTHEVVTLWYRAPEILMGAQRYSMG 202
Query: 277 VDIWGIGCVFAEFFEKKPILQGQTDIDQGHVIFKLMGTPSMDEWGLAYHLPGSELTKTNY 336
VD+W IGC+FAE KKP+ QG ++ID+ IF+++GTP+ EW LP + T +
Sbjct: 203 VDMWSIGCIFAEMATKKPLFQGDSEIDELFRIFRVLGTPTELEWNGVESLPDYKATFPKW 262
Query: 337 KST-LQERF------SKALNETGXXXXXXXXXXDPYKRVTAMKAKKHPFF 379
+ L+++F L++T DP R+ A KA HP+F
Sbjct: 263 RENFLRDKFYDKKTGKHLLDDTAFSLLEGLLIYDPSLRLNAKKALVHPYF 312
>At1g71530 [D] KOG0600 Cdc2-related protein kinase
Length = 655
Score = 185 bits (469), Expect = 2e-46
Identities = 136/428 (31%), Positives = 203/428 (46%), Gaps = 65/428 (15%)
Query: 19 KQIPTVVKDDKTGLEYIQ----VQSRENEKVYG-VTKFLNNYREEEKLGQGTFGEVFKGI 73
+Q P V +KT L + + S E + G V + ++ + +K+GQGT+ V+K
Sbjct: 106 QQQPARVISNKTELPAAEWPSWLASVAGEAIKGWVPRCAESFEKLDKIGQGTYSSVYKAR 165
Query: 74 HLGTNRKVAIKRI-LVRAEKDLFPITAQREITILKRMNHKNIVKLIEIVYDESPTPKTDS 132
L T + VA+K++ V + + A REI IL++++H N++KL +V
Sbjct: 166 DLETGKIVAMKKVRFVNMDPESVRFMA-REILILRKLDHPNVMKLEGLVTSR-------- 216
Query: 133 TSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGLLHNPRVEFGMADVKNIMLQL 192
++G +++ YM DL GL P ++F +K M QL
Sbjct: 217 --------------------LSGS-LYLVFEYMEHDLAGLAATPGIKFSEPQIKCYMQQL 255
Query: 193 LEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLARNYYGSPPNLKYPGGAGSGAKY 252
G+ + H LHRDIK +N+LI+++GV+KI DFGLA Y G +
Sbjct: 256 FRGLEHCHRRGILHRDIKGSNLLINNEGVLKIGDFGLANFYRGD-----------GDLQL 304
Query: 253 TSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFEKKPILQGQTDIDQGHVIFKLM 312
TS VVT WYRAPE++LG Y A+D+W GC+ E F KPI+ G+T+++Q H IFKL
Sbjct: 305 TSRVVTLWYRAPELLLGATEYGPAIDLWSAGCILTELFAGKPIMPGRTEVEQMHKIFKLC 364
Query: 313 GTPSMDEWGLAYHLPGSELTKTN--YKSTLQERFSKALNETGXXXXXXXXXXDPYKRVTA 370
G+PS D W A LP + K + YK L E F+ + +P KR +A
Sbjct: 365 GSPSEDYWRRA-TLPLATSFKPSHPYKPVLAETFNH-FPSSALMLINKLLAIEPEKRGSA 422
Query: 371 MKAKKHPFFFEEPLPNAQLTLP-------------NEECHESDIKRYKSEMNESMSQ-RP 416
+ FF EPLP LP NEE + + K E++++ RP
Sbjct: 423 ASTLRSEFFTTEPLPANPSNLPRYPPSKELDAKLRNEEARKLRAEGNKRRGGETVTRGRP 482
Query: 417 PSAPTGHT 424
T T
Sbjct: 483 KDLKTAQT 490
>YBR160w [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 298
Score = 184 bits (468), Expect = 3e-46
Identities = 112/335 (33%), Positives = 174/335 (51%), Gaps = 47/335 (14%)
Query: 52 LNNYREEEKLGQGTFGEVFKGIHLGTN---RKVAIKRILVRAEKDLFPITAQREITILKR 108
L NY+ EK+G+GT+G V+K + L R VA+K+I + +E + P TA REI++LK
Sbjct: 5 LANYKRLEKVGEGTYGVVYKALDLRPGQGQRVVALKKIRLESEDEGVPSTAIREISLLKE 64
Query: 109 MNHKNIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSD 168
+ NIV+L +IV+ ++ +++ ++ D
Sbjct: 65 LKDDNIVRLYDIVHSDA------------------------------HKLYLVFEFLDLD 94
Query: 169 LTGLLHN-PRVE-FGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIAD 226
L + P+ + G VK M+QL +GI Y H ++ LHRD+K N+LI+ G +K+ D
Sbjct: 95 LKRYMEGIPKDQPLGADIVKKFMMQLCKGIAYCHSHRILHRDLKPQNLLINKDGNLKLGD 154
Query: 227 FGLARNYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVF 286
FGLAR + G P YT +VT WYRAPE++LG + Y+T VD W IGC+F
Sbjct: 155 FGLARAF-GVPLRA-----------YTHEIVTLWYRAPEVLLGGKQYSTGVDTWSIGCIF 202
Query: 287 AEFFEKKPILQGQTDIDQGHVIFKLMGTPSMDEWGLAYHLPGSELTKTNYKSTLQERFSK 346
AE +KPI G ++IDQ IF+++GTP+ W +LP + + ++ +
Sbjct: 203 AEMCNRKPIFSGDSEIDQIFKIFRVLGTPNEAIWPDIVYLPDFKPSFPQWRRKDLSQVVP 262
Query: 347 ALNETGXXXXXXXXXXDPYKRVTAMKAKKHPFFFE 381
+L+ G DP R++A +A HP+F E
Sbjct: 263 SLDPRGIDLLDKLLAYDPINRISARRAAIHPYFQE 297
>At1g53050 [D] KOG0600 Cdc2-related protein kinase
Length = 694
Score = 184 bits (466), Expect = 5e-46
Identities = 131/435 (30%), Positives = 199/435 (45%), Gaps = 66/435 (15%)
Query: 48 VTKFLNNYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILK 107
V + +++ + +K+GQGT+ V++ L + VA+K++ + REI IL+
Sbjct: 127 VPRRADSFEKLDKIGQGTYSNVYRARDLDQKKIVALKKVRFDNLEPESVRFMAREIQILR 186
Query: 108 RMNHKNIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGK---HFFMILPY 164
R++H NI+KL + L+T + +++ Y
Sbjct: 187 RLDHPNIIKL--------------------------------EGLVTSRMSCSLYLVFEY 214
Query: 165 MVSDLTGLLHNPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKI 224
M DL GL +P ++F + VK + QLL G+++ H LHRDIK +N+LID+ GV+KI
Sbjct: 215 MEHDLAGLASHPAIKFSESQVKCYLQQLLHGLDHCHSRGVLHRDIKGSNLLIDNSGVLKI 274
Query: 225 ADFGLARNYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGC 284
ADFGLA + P P TS VVT WYR PE++LG Y AVD+W GC
Sbjct: 275 ADFGLASFF---DPRQTQP--------LTSRVVTLWYRPPELLLGATRYGAAVDLWSAGC 323
Query: 285 VFAEFFEKKPILQGQTDIDQGHVIFKLMGTPSMDEWGLAYHLPGSELTKTN--YKSTLQE 342
+ AE + KPI+ G+T+++Q H IFKL G+P+ D W + LP + + K YK + E
Sbjct: 324 ILAELYAGKPIMPGRTEVEQLHKIFKLCGSPTEDYW-VKSRLPHATIFKPTQPYKRLVGE 382
Query: 343 RFSKALNETGXXXXXXXXXXDPYKRVTAMKAKKHPFFFEEPLPNAQLTLP--------NE 394
F K + +P R TA A K FF PLP +LP +
Sbjct: 383 TF-KEFPQPALALLETLLSVNPDDRGTATAALKSEFFSTRPLPCDPSSLPKYPPSKELDA 441
Query: 395 ECHESDIKRY--------KSEMNESMSQRPPSAPTGHTSTDNSIRAVTGAAFPKEASIPK 446
+ + +R E + R AP + S++ + + S
Sbjct: 442 RMRDEESRRQVGGNRDQRHQERRGTKESRAIPAPDANAELVASMQKRQSQSTNRSRSEKF 501
Query: 447 APRPEHIKSTIPAQP 461
P PE + S P P
Sbjct: 502 NPHPEEVASGFPIDP 516
>At5g39420 [D] KOG0600 Cdc2-related protein kinase
Length = 576
Score = 183 bits (464), Expect = 8e-46
Identities = 117/321 (36%), Positives = 168/321 (51%), Gaps = 44/321 (13%)
Query: 55 YREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNHKNI 114
+++ EK+GQGT+ VF+ + T + VA+K++ + REI IL+++NH NI
Sbjct: 105 FQKLEKIGQGTYSSVFRAREVETGKMVALKKVKFDNLQPESIRFMAREILILRKLNHPNI 164
Query: 115 VKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGLLH 174
+KL IV T + S+ +++ YM DL GL
Sbjct: 165 MKLEGIV-----TSRASSS------------------------IYLVFEYMEHDLAGLSS 195
Query: 175 NPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLARNYY 234
NP + F +K M QLL G+ + H +HRDIK +NIL+++KGV+K+ DFGLA
Sbjct: 196 NPDIRFTEPQIKCYMKQLLWGLEHCHMRGVIHRDIKASNILVNNKGVLKLGDFGLANVVT 255
Query: 235 GSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFEKKP 294
S N + TS VVT WYRAPE+++G Y +VD+W +GCVFAE KP
Sbjct: 256 PSNKN-----------QLTSRVVTLWYRAPELLMGSTSYGVSVDLWSVGCVFAEILMGKP 304
Query: 295 ILQGQTDIDQGHVIFKLMGTPSMDEWGLAYHLPGSELTKT--NYKSTLQERFSKALNETG 352
IL+G+T+I+Q H I+KL G+P W LP + K Y++TL+ER K L+ TG
Sbjct: 305 ILKGRTEIEQLHKIYKLCGSPQDSFWKRT-KLPHATSFKPQHTYEATLRER-CKDLSATG 362
Query: 353 XXXXXXXXXXDPYKRVTAMKA 373
+P KR TA A
Sbjct: 363 VYLLETLLSMEPDKRGTASSA 383
>At1g33770 [D] KOG0600 Cdc2-related protein kinase
Length = 614
Score = 183 bits (464), Expect = 8e-46
Identities = 132/413 (31%), Positives = 199/413 (47%), Gaps = 63/413 (15%)
Query: 48 VTKFLNNYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILK 107
V + +++ + +K+GQGT+ V+K L T + VA+K++ REI IL+
Sbjct: 134 VPRRADSFEKLDKIGQGTYSIVYKARDLETGKIVAMKKVRFANMDPESVRFMAREINILR 193
Query: 108 RMNHKNIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGK---HFFMILPY 164
+++H N++KL Q L+T K ++ Y
Sbjct: 194 KLDHPNVMKL--------------------------------QCLVTSKLSGSLHLVFEY 221
Query: 165 MVSDLTGLLHNPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKI 224
M DL+GL P V+F +K M QLL G+ + H LHRDIK +N+L+++ GV+KI
Sbjct: 222 MEHDLSGLALRPGVKFTEPQIKCFMKQLLCGLEHCHSRGILHRDIKGSNLLVNNDGVLKI 281
Query: 225 ADFGLARNYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGC 284
DFGLA Y P+ P TS VVT WYRAPE++LG Y A+D+W +GC
Sbjct: 282 GDFGLASFY---KPDQDQP--------LTSRVVTLWYRAPELLLGSTEYGPAIDLWSVGC 330
Query: 285 VFAEFFEKKPILQGQTDIDQGHVIFKLMGTPSMDEWGLA-YHLPGSELTKTNYKSTLQER 343
+ AE F KPI+ G+T+++Q H IFKL G+PS + W + S + YK L E
Sbjct: 331 ILAELFVCKPIMPGRTEVEQMHKIFKLCGSPSEEFWNTTKFPQATSYKPQHPYKRVLLET 390
Query: 344 FSKALNETGXXXXXXXXXXDPYKRVTAMKAKKHPFFFEEPLPNAQLTLP--------NEE 395
F K L+ + +P KR +A FF EPLP +LP + +
Sbjct: 391 F-KNLSSSSLDLLDKLLSVEPEKRCSASSTLLSEFFTTEPLPCHISSLPKYPPSKELDAK 449
Query: 396 CHESDIKRYKSEM-----NESMSQ--RPPSAPTGHTSTDNSIRAVTGAAFPKE 441
+ + KR K+E +ES+ + R ++ NS ++T +F KE
Sbjct: 450 VRDEEAKRKKAEAVKWRGHESVRRGLRDSKVTPEFIASGNSNVSLTTPSFKKE 502
>At4g10010 [D] KOG0600 Cdc2-related protein kinase
Length = 649
Score = 182 bits (463), Expect = 1e-45
Identities = 123/373 (32%), Positives = 182/373 (47%), Gaps = 58/373 (15%)
Query: 48 VTKFLNNYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRI-LVRAEKDLFPITAQREITIL 106
V + ++ + +K+GQGT+ V++ L T + VA+K++ V + + A REI IL
Sbjct: 149 VPRRAESFEKLDKIGQGTYSSVYRARDLETGKMVAMKKVRFVNMDPESVRFMA-REINIL 207
Query: 107 KRMNHKNIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGK---HFFMILP 163
++++H N++KL + L+T K +++
Sbjct: 208 RKLDHPNVMKL--------------------------------ECLVTSKLSGSLYLVFE 235
Query: 164 YMVSDLTGLLHNPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVK 223
YM DL+GL P V+F + +K M QLL G+ + H LHRDIK N+L+++ GV+K
Sbjct: 236 YMEHDLSGLALRPGVKFTESQIKCYMKQLLSGLEHCHSRGILHRDIKGPNLLVNNDGVLK 295
Query: 224 IADFGLARNYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIG 283
I DFGLA Y+ P P TS VVT WYRAPE++LG Y +D+W +G
Sbjct: 296 IGDFGLANIYH---PEQDQP--------LTSRVVTLWYRAPELLLGATEYGPGIDLWSVG 344
Query: 284 CVFAEFFEKKPILQGQTDIDQGHVIFKLMGTPSMDEW-GLAYHLPGSELTKTNYKSTLQE 342
C+ E F KPI+ G+T+++Q H IFK G+PS D W L S + YK L E
Sbjct: 345 CILTELFLGKPIMPGRTEVEQMHKIFKFCGSPSDDYWQKTKLPLATSFKPQQPYKRVLLE 404
Query: 343 RFSKALNETGXXXXXXXXXXDPYKRVTAMKAKKHPFFFEEPLPNAQLTLP--------NE 394
F K L + +P KR TA FF EPLP +LP +
Sbjct: 405 TF-KNLPPSALALVDKLLSLEPAKRGTASSTLSSKFFTMEPLPCNVSSLPKYPPSKELDA 463
Query: 395 ECHESDIKRYKSE 407
+ + + +R KSE
Sbjct: 464 KVRDEEARRKKSE 476
>At1g18040 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 391
Score = 182 bits (462), Expect = 1e-45
Identities = 112/343 (32%), Positives = 168/343 (48%), Gaps = 44/343 (12%)
Query: 50 KFLNNYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRM 109
K + Y ++E LGQGT+G VFK T + VAIK+I + +++ ITA REI +LK +
Sbjct: 7 KVADRYLKQEVLGQGTYGVVFKATDTKTEQTVAIKKIRLGKQREGVNITALREIKMLKEL 66
Query: 110 NHKNIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDL 169
H +I+ LI+ + N H ++ +M +DL
Sbjct: 67 KHPHIILLIDAFPHKE--------------NLH-----------------LVFEFMETDL 95
Query: 170 TGLLHNPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGL 229
++ + + AD+K+ +L +G+ Y H LHRD+K N+LI G +K+ADFGL
Sbjct: 96 EAVIRDSNIFLSPADIKSYLLMTFKGLAYCHDKWVLHRDMKPNNLLIGVDGQLKLADFGL 155
Query: 230 ARNYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEF 289
AR +GSP K+T V RWYRAPE++ G + Y AVD+W + C+FAE
Sbjct: 156 AR-IFGSP-----------NRKFTHQVFARWYRAPELLFGAKQYGAAVDVWAVACIFAEL 203
Query: 290 FEKKPILQGQTDIDQGHVIFKLMGTPSMDEWGLAYHLPGSELTKTNYKSTLQERFSKALN 349
++P LQG +DIDQ IF GTP D+W LP + +L+ F A++
Sbjct: 204 LLRRPFLQGNSDIDQLSKIFAAFGTPKADQWPDLTKLPDYVEYQFVPAPSLRSLF-PAVS 262
Query: 350 ETGXXXXXXXXXXDPYKRVTAMKAKKHPFFFEEPLPNAQLTLP 392
+ DP R++ +A +H +F P P LP
Sbjct: 263 DDALDLLSKMFTYDPKARISIKQALEHRYFTSAPAPTDPAKLP 305
>CE18009 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 384
Score = 182 bits (461), Expect = 2e-45
Identities = 105/326 (32%), Positives = 164/326 (50%), Gaps = 31/326 (9%)
Query: 60 KLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNHKNIVKLIE 119
++G+GT+G VFK IH+ N K A+K I +++ P T REI+ +K + H NIV L +
Sbjct: 50 RIGEGTYGVVFKAIHVRDNVKCALKMIRTDRDEEGIPSTCLREISCIKDLQHDNIVTLFD 109
Query: 120 IVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGLLHNPRVE 179
I+Y ++ N +K + +M+ ++ DL LL
Sbjct: 110 IIY---------------ASHFLNYNNIFFEKFSSNSKLYMVFEFIDRDLKNLLEMLEPT 154
Query: 180 FGMAD---VKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLARNYYGS 236
+ VK+ M QLL ++Y H + +HRD+K NIL+ GV+KIADFGLARN+
Sbjct: 155 NSVLPPNYVKSFMWQLLSALSYCHLRRIVHRDLKPQNILVSDSGVIKIADFGLARNF--- 211
Query: 237 PPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFEKKPIL 296
+P YT VVT WYR PEI+LG + Y+T++D+W +GC+F+E KP+
Sbjct: 212 ----SFPS-----RNYTHEVVTLWYRPPEILLGSQRYSTSLDMWSLGCIFSEIASNKPLF 262
Query: 297 QGQTDIDQGHVIFKLMGTPSMDEWGLAYHLPGSELTKTNYKSTLQE-RFSKALNETGXXX 355
G+ +I Q IF+++GTP++ W P + + L++ + L G
Sbjct: 263 PGECEISQLFKIFEIVGTPNIKSWPGVDSFPHYKAVFPQWPVNLKKLEETSCLTGNGLDV 322
Query: 356 XXXXXXXDPYKRVTAMKAKKHPFFFE 381
P +R+TA A H +F +
Sbjct: 323 LREILRYPPERRLTAKGALSHRYFLQ 348
>At1g66750 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 348
Score = 179 bits (454), Expect = 1e-44
Identities = 113/371 (30%), Positives = 173/371 (46%), Gaps = 44/371 (11%)
Query: 52 LNNYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNH 111
++ Y + LG+GT+G V+K T + VA+K+I + +K+ TA REI +LK +NH
Sbjct: 10 VDRYLRRQILGEGTYGVVYKATDTKTGKTVAVKKIRLGNQKEGVNFTALREIKLLKELNH 69
Query: 112 KNIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTG 171
+IV+LI+ + G+ H ++ YM +DL
Sbjct: 70 PHIVELIDAFPHD--------------GSLH-----------------LVFEYMQTDLEA 98
Query: 172 LLHNPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLAR 231
++ + + D+K+ ML L+G+ Y H LHRD+K N+LI G++K+ADFGLAR
Sbjct: 99 VIRDRNIFLSPGDIKSYMLMTLKGLAYCHKKWVLHRDMKPNNLLIGENGLLKLADFGLAR 158
Query: 232 NYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFE 291
+GSP ++T V WYRAPE++ G R Y VD+W GC+FAE
Sbjct: 159 -LFGSP-----------NRRFTHQVFATWYRAPELLFGSRQYGAGVDVWAAGCIFAELLL 206
Query: 292 KKPILQGQTDIDQGHVIFKLMGTPSMDEWGLAYHLPGSELTKTNYKSTLQERFSKALNET 351
++P L G T+IDQ IF+ GTP +W +LP L+ F A ++
Sbjct: 207 RRPFLPGSTEIDQLGKIFQAFGTPVPSQWSDMIYLPDYMEFSYTPAPPLRTIFPMA-SDD 265
Query: 352 GXXXXXXXXXXDPYKRVTAMKAKKHPFFFEEPLPNAQLTLPNEECHESDIKRYKSEMNES 411
DP +R+T +A H +F P P L ++ SE N+
Sbjct: 266 ALDLLAKMFIYDPRQRITIQQALDHRYFSSSPSPTEPGKLQIPASKGDALEPKASEQNQH 325
Query: 412 MSQRPPSAPTG 422
+ +P G
Sbjct: 326 GNSPAVLSPPG 336
>7297680 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 297
Score = 179 bits (453), Expect = 2e-44
Identities = 104/330 (31%), Positives = 172/330 (51%), Gaps = 45/330 (13%)
Query: 52 LNNYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNH 111
+ ++ + EK+G+GT+G V+KG + T + VA+K+I + ++ + P TA REI++LK + H
Sbjct: 1 MEDFEKIEKIGEGTYGVVYKGRNRLTGQIVAMKKIRLESDDEGVPSTAIREISLLKELKH 60
Query: 112 KNIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTG 171
+NIV L +++ +E+ ++I ++ DL
Sbjct: 61 ENIVCLEDVLMEEN-------------------------------RIYLIFEFLSMDLKK 89
Query: 172 LLHNPRVEFGMAD--VKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGL 229
+ + V+ M V++ + Q+ I + H + LHRD+K N+LID G++K+ADFGL
Sbjct: 90 YMDSLPVDKHMESELVRSYLYQITSAILFCHRRRVLHRDLKPQNLLIDKSGLIKVADFGL 149
Query: 230 ARNYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEF 289
R++ G P + YT +VT WYRAPE++LG Y+ VDIW IGC+FAE
Sbjct: 150 GRSF-GIPVRI-----------YTHEIVTLWYRAPEVLLGSPRYSCPVDIWSIGCIFAEM 197
Query: 290 FEKKPILQGQTDIDQGHVIFKLMGTPSMDEWGLAYHLPGSELTKTNYKSTLQERFSKALN 349
+KP+ QG ++IDQ +F+++ TP+ D W LP + T + + K L+
Sbjct: 198 ATRKPLFQGDSEIDQLFRMFRILKTPTEDIWPGVTSLPDYKNTFPCWSTNQLTNQLKNLD 257
Query: 350 ETGXXXXXXXXXXDPYKRVTAMKAKKHPFF 379
G DP R++A +HP+F
Sbjct: 258 ANGIDLIQKMLIYDPVHRISAKDILEHPYF 287
>At5g63610 [K] KOG0666 Cyclin C-dependent kinase CDK8
Length = 470
Score = 177 bits (449), Expect = 4e-44
Identities = 122/371 (32%), Positives = 176/371 (46%), Gaps = 86/371 (23%)
Query: 50 KFLNNYREEEKLGQGTFGEVFKG-IHLGTNRKVAIKRILVRAEKDLFPITAQREITILKR 108
++L Y K+G+GT+G VF R +AIK+ + D TA REI +L+
Sbjct: 20 EWLQQYNLVGKIGEGTYGLVFLARTKTPPKRPIAIKKFKQSKDGDGVSPTAIREIMLLRE 79
Query: 109 MNHKNIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSD 168
++H+N+VKL+ N H N ++ Y D
Sbjct: 80 ISHENVVKLV---------------------NVHIN--------FADMSLYLAFDYAEYD 110
Query: 169 LTGLLHNPRVEFGMA----DVKNIMLQLLEGINYIHCNKFLHRDIKTANILI----DHKG 220
L ++ + R + G + VK+++ QLL G+NY+H N +HRD+K +NIL+ + G
Sbjct: 111 LYEIIRHHRDKVGHSLNTYTVKSLLWQLLNGLNYLHSNWIIHRDLKPSNILVMGDAEEHG 170
Query: 221 VVKIADFGLARNYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIW 280
+VKIADFGLAR Y L G VVVT WYRAPE++LG +HYT+AVD+W
Sbjct: 171 IVKIADFGLARIYQAPLKPLSDNG----------VVVTIWYRAPELLLGSKHYTSAVDMW 220
Query: 281 GIGCVFAEFFEKKPILQGQT--------DIDQGHVIFKLMGTPSMDEWGLAYHLPG---- 328
+GC+FAE KP+ QG +DQ IFK++G P+MD+W +LP
Sbjct: 221 AVGCIFAELLTLKPLFQGAEAKSSQNPFQLDQLDKIFKILGHPTMDKWPTLVNLPHWQND 280
Query: 329 --------------SELTKTNYKSTLQERFSKALNETGXXXXXXXXXXDPYKRVTAMKAK 374
+ N KS + SK L DP KR+TA +A
Sbjct: 281 VQHIQAHKYDSVGLHNVVHLNQKSPAYDLLSKMLE------------YDPLKRITASQAL 328
Query: 375 KHPFFFEEPLP 385
+H +F +PLP
Sbjct: 329 EHEYFRMDPLP 339
>7303804 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 387
Score = 176 bits (446), Expect = 1e-43
Identities = 108/344 (31%), Positives = 178/344 (51%), Gaps = 46/344 (13%)
Query: 43 EKVYGVTKFLNNYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQRE 102
+ ++G + ++ + + ++G+G++G V++ +N VA+K++ + EKD PI+ RE
Sbjct: 41 QNLFGRCRPVSEFEKLNRVGEGSYGIVYRARDTRSNEIVALKKVRMDQEKDGLPISGLRE 100
Query: 103 ITILKRMNHKNIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMIL 162
I ILK+ +H+NIV+L E+V +S DS F+++
Sbjct: 101 IMILKQCHHENIVRLREVVVGKS----LDS-------------------------IFLVM 131
Query: 163 PYMVSDLTGLLHNPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVV 222
+ DL +L N F ++VK I LQ+L+ + Y+H +HRD+K +N+L+ KG +
Sbjct: 132 DFCEQDLASVLDNMSQPFTESEVKCITLQVLKALKYLHSRFMIHRDLKVSNLLMTDKGCI 191
Query: 223 KIADFGLARNYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGI 282
K+ADFGLAR + P + T +VT WYRAPE++LG R +TTAVD+W
Sbjct: 192 KVADFGLARMFSNPPKPM------------TPQMVTLWYRAPELLLGCRTHTTAVDMWAF 239
Query: 283 GCVFAEFFEKKPILQGQTDIDQGHVIFKLMGTPSMDEWGLAYHLPGSE---LTKTNYKST 339
GC+ E KP+L G ++I Q +I L+G PS W LP + L++ Y +
Sbjct: 240 GCILGELLLGKPLLPGNSEIAQLDMIIDLLGAPSESIWPGFADLPAVQNFTLSQQPY-NN 298
Query: 340 LQERFSKALNETGXXXXXXXXXXDPYKRVTAMKAKKHPFFFEEP 383
L +F + ++G +P R TA + K +F + P
Sbjct: 299 LTPKF-HMIGQSGRNLLNILFIYNPKTRATAEECLKSKYFVDPP 341
>At5g44290 [D] KOG0600 Cdc2-related protein kinase
Length = 644
Score = 175 bits (443), Expect = 2e-43
Identities = 119/343 (34%), Positives = 169/343 (48%), Gaps = 46/343 (13%)
Query: 53 NNYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQ-REITILKRMNH 111
+ + + EK+GQGT+ V+K L N+ VA+KR+ DL + REI +++R++H
Sbjct: 135 STFEKLEKIGQGTYSSVYKARDLTNNKIVALKRVRFDLS-DLESVKFMAREIIVMRRLDH 193
Query: 112 KNIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTG 171
N++KL ++ T S S +++ YM DL G
Sbjct: 194 PNVLKLEGLI--------TASVS---------------------SSLYLVFEYMDHDLVG 224
Query: 172 LLHNPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLAR 231
L P ++F VK M QLL G+++ H LHRDIK +N+LID GV+KIADFGLA
Sbjct: 225 LASIPGIKFSEPQVKCYMQQLLSGLHHCHSRGVLHRDIKGSNLLIDSNGVLKIADFGLAT 284
Query: 232 NYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFE 291
+ P N TS VVT WYR PE++LG HY VD+W GC+ E +
Sbjct: 285 FF--DPQNC---------VPLTSRVVTLWYRPPELLLGACHYGVGVDLWSTGCILGELYS 333
Query: 292 KKPILQGQTDIDQGHVIFKLMGTPSMDEWGLAYHLPGSELTK--TNYKSTLQERFSKALN 349
KPIL G+T+++Q H IFKL G+P+ D W LP S + Y + E F K L
Sbjct: 334 GKPILAGKTEVEQLHKIFKLCGSPTEDYW-RKLKLPPSAAFRPALPYGRRVAEMF-KDLP 391
Query: 350 ETGXXXXXXXXXXDPYKRVTAMKAKKHPFFFEEPLPNAQLTLP 392
DP +R +A +A + +F EP +LP
Sbjct: 392 TNVLSLLEALLSIDPDRRGSAARALESEYFRTEPFACDPSSLP 434
>SPBC11B10.09 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 297
Score = 174 bits (442), Expect = 3e-43
Identities = 103/292 (35%), Positives = 160/292 (54%), Gaps = 50/292 (17%)
Query: 52 LNNYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNH 111
+ NY++ EK+G+GT+G V+K H + R VA+K+I + E + P TA REI++LK +N
Sbjct: 1 MENYQKVEKIGEGTYGVVYKARHKLSGRIVAMKKIRLEDESEGVPSTAIREISLLKEVND 60
Query: 112 KN----IVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVS 167
+N V+L++I++ ES + Y +S
Sbjct: 61 ENNRSNCVRLLDILHAESKLYLVFEFLDMDLKKYMDR---------------------IS 99
Query: 168 DLTGLLHNPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADF 227
+ +PR+ V+ QL+ G+N+ H + +HRD+K N+LID +G +K+ADF
Sbjct: 100 ETGATSLDPRL------VQKFTYQLVNGVNFCHSRRIIHRDLKPQNLLIDKEGNLKLADF 153
Query: 228 GLARNYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFA 287
GLAR++ G P YT +VT WYRAPE++LG RHY+T VDIW +GC+FA
Sbjct: 154 GLARSF-GVPLR-----------NYTHEIVTLWYRAPEVLLGSRHYSTGVDIWSVGCIFA 201
Query: 288 EFFEKKPILQGQTDIDQGHVIFKLMGTPSMDEWGLAYHLPGSELTKTNYKST 339
E + P+ G ++ID+ IF+++GTP+ + W PG L + +YKST
Sbjct: 202 EMIRRSPLFPGDSEIDEIFKIFQVLGTPNEEVW------PGVTLLQ-DYKST 246
>YDL108w [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 306
Score = 174 bits (441), Expect = 4e-43
Identities = 111/339 (32%), Positives = 170/339 (49%), Gaps = 55/339 (16%)
Query: 55 YREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNHKNI 114
Y +E+K+G+GT+ V+ G T RK+AIK I KD ++A RE+ L+ M H N+
Sbjct: 7 YTKEKKVGEGTYAVVYLGCQHSTGRKIAIKEIKTSEFKDGLDMSAIREVKYLQEMQHPNV 66
Query: 115 VKLIEI--VYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGL 172
++LI+I YD + ++L ++ +DL +
Sbjct: 67 IELIDIFMAYD---------------------------------NLNLVLEFLPTDLEVV 93
Query: 173 LHNPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLARN 232
+ + + F AD+K ML L G+ + H N LHRD+K N+L G +K+ADFGLAR
Sbjct: 94 IKDKSILFTPADIKAWMLMTLRGVYHCHRNFILHRDLKPNNLLFSPDGQIKVADFGLARA 153
Query: 233 YYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFEK 292
L TS VVTRWYRAPE++ G +HYT+A+DIW +G +FAE +
Sbjct: 154 IPAPHEIL------------TSNVVTRWYRAPELLFGAKHYTSAIDIWSVGVIFAELMLR 201
Query: 293 KPILQGQTDIDQGHVIFKLMGTPSMDEWG-----LAYHLPGSELTKTNYKSTLQERFSKA 347
P L GQ D+DQ V F+ +GTP+ +W + Y+ ++ + L++RF A
Sbjct: 202 IPYLPGQNDVDQMEVTFRALGTPTDRDWPEVSSFMTYN--KLQIYPPPSRDELRKRFI-A 258
Query: 348 LNETGXXXXXXXXXXDPYKRVTAMKAKKHPFFFEEPLPN 386
+E +P KR TA++ + +F E P P+
Sbjct: 259 ASEYALDFMCGMLTMNPQKRWTAVQCLESDYFKELPPPS 297
>7303051 [UT] KOG0662 Cyclin-dependent kinase CDK5
Length = 294
Score = 174 bits (441), Expect = 4e-43
Identities = 104/329 (31%), Positives = 164/329 (49%), Gaps = 44/329 (13%)
Query: 52 LNNYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNH 111
+ Y + EK+G+GT+G VFKG + T VA+KR+ + + + P +A REI +LK + H
Sbjct: 1 MQKYDKMEKIGEGTYGTVFKGRNRDTMEIVALKRVRLDEDDEGVPSSALREICLLKELKH 60
Query: 112 KNIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTG 171
KNIV+LI++++ + K ++ + DL
Sbjct: 61 KNIVRLIDVLHSD-------------------------------KKLTLVFEHCDQDLKK 89
Query: 172 LLHNPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLAR 231
+ E MA ++ MLQLL G+ + H + LHRD+K N+LI+ G +K+ADFGLAR
Sbjct: 90 YFDSLNGEIDMAVCRSFMLQLLRGLAFCHSHNVLHRDLKPQNLLINKNGELKLADFGLAR 149
Query: 232 NYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFE 291
+G P Y++ VVT WYR P+++ G + YTT++D+W GC+ AE +
Sbjct: 150 -AFGIPVKC-----------YSAEVVTLWYRPPDVLFGAKLYTTSIDMWSAGCILAELAD 197
Query: 292 K-KPILQGQTDIDQGHVIFKLMGTPSMDEWGLAYHLPGSELTKTNYKSTLQERFSKALNE 350
+P+ G +DQ IF+++GTP+ D W HL + T + LN
Sbjct: 198 AGRPLFPGSDVLDQLMKIFRVLGTPNEDSWPGVSHLSDYVALPSFPAITSWSQLVPRLNS 257
Query: 351 TGXXXXXXXXXXDPYKRVTAMKAKKHPFF 379
G P +R++A A +HP+F
Sbjct: 258 KGRDLLQKLLICRPNQRISAEAAMQHPYF 286
>Hs7705551 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 632
Score = 174 bits (440), Expect = 5e-43
Identities = 118/421 (28%), Positives = 189/421 (44%), Gaps = 64/421 (15%)
Query: 52 LNNYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNH 111
+N Y +LG GT+G V G + + +AIK+ + R QRE+ LK++NH
Sbjct: 1 MNRYTTIRQLGDGTYGSVLLGRSIESGELIAIKK-MKRKFYSWEECMNQREVKSLKKLNH 59
Query: 112 KNIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTG 171
N+VKL E++ + H + I YM +L
Sbjct: 60 ANVVKLKEVIREND-------------------------------HLYFIFEYMKENLYQ 88
Query: 172 LLHNPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLAR 231
L+ F + ++NIM Q+L+G+ +IH F HRD+K N+L +VKIADFGLAR
Sbjct: 89 LIKERNKLFPESAIRNIMYQILQGLAFIHKLGFFHRDLKPENLLCMGPELVKIADFGLAR 148
Query: 232 NYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFE 291
PP YT V TRWYRAPE++L +Y++ +D+W +GC+ AE +
Sbjct: 149 EIRSKPP-------------YTDYVSTRWYRAPEVLLRSTNYSSPIDVWAVGCIMAEVYT 195
Query: 292 KKPILQGQTDIDQGHVIFKLMGTPSMDEWGLAYHLPGS------ELTKTNYKSTLQERFS 345
+P+ G ++ID I +++GTP +W Y L + + N K+ + S
Sbjct: 196 LRPLFPGASEIDTIFKICQVLGTPKKTDWPEGYQLSSAMNFRWPQCVPNNLKTLIPNASS 255
Query: 346 KALNETGXXXXXXXXXXDPYKRVTAMKAKKHPFF-FEEPLPNAQLTLPNEECHESDIKRY 404
+A+ DP KR TA +A ++P+F PL + L + E + I
Sbjct: 256 EAVQ-----LLRDMLQWDPKKRPTASQALRYPYFQVGHPLGSTTQNLQDSEKPQKGILE- 309
Query: 405 KSEMNESMSQRPPSAPTGHTSTDNSIRAVTGA------AFPKEASIPKAPRPEHIKSTIP 458
++ + PP+ P T S R + +P +A + + P H++ P
Sbjct: 310 RAGPPPYIKPVPPAQPPAKPHTRISSRQHQASQPPLHLTYPYKAEVSRTDHPSHLQEDKP 369
Query: 459 A 459
+
Sbjct: 370 S 370
>Hs7662388 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 632
Score = 174 bits (440), Expect = 5e-43
Identities = 118/421 (28%), Positives = 189/421 (44%), Gaps = 64/421 (15%)
Query: 52 LNNYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNH 111
+N Y +LG GT+G V G + + +AIK+ + R RE+ LK++NH
Sbjct: 1 MNRYTTIRQLGDGTYGSVLLGRSIESGELIAIKK-MKRKFYSWEECMNLREVKSLKKLNH 59
Query: 112 KNIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTG 171
N+VKL E++ + H + I YM +L
Sbjct: 60 ANVVKLKEVIREND-------------------------------HLYFIFEYMKENLYQ 88
Query: 172 LLHNPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLAR 231
L+ F + ++NIM Q+L+G+ +IH + F HRD+K N+L +VKIADFGLAR
Sbjct: 89 LIKERNKLFPESAIRNIMYQILQGLAFIHKHGFFHRDLKPENLLCMGPELVKIADFGLAR 148
Query: 232 NYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFE 291
PP YT V TRWYRAPE++L +Y++ +D+W +GC+ AE +
Sbjct: 149 EIRSKPP-------------YTDYVSTRWYRAPEVLLRSTNYSSPIDVWAVGCIMAEVYT 195
Query: 292 KKPILQGQTDIDQGHVIFKLMGTPSMDEWGLAYHLPGS------ELTKTNYKSTLQERFS 345
+P+ G ++ID I +++GTP +W Y L + + N K+ + S
Sbjct: 196 LRPLFPGASEIDTIFKICQVLGTPKKTDWPEGYQLSSAMNFRWPQCVPNNLKTLIPNASS 255
Query: 346 KALNETGXXXXXXXXXXDPYKRVTAMKAKKHPFF-FEEPLPNAQLTLPNEECHESDIKRY 404
+A+ DP KR TA +A ++P+F PL + L + E + I
Sbjct: 256 EAVQ-----LLRDMLQWDPKKRPTASQALRYPYFQVGHPLGSTTQNLQDSEKPQKGILE- 309
Query: 405 KSEMNESMSQRPPSAPTGHTSTDNSIRAVTGA------AFPKEASIPKAPRPEHIKSTIP 458
K+ + PP+ P T S R + +P +A + + P H++ P
Sbjct: 310 KAGPPPYIKPVPPAQPPAKPHTRISSRQHQASQPPLHLTYPYKAEVSRTDHPSHLQEDKP 369
Query: 459 A 459
+
Sbjct: 370 S 370
>Hs4505649 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 523
Score = 172 bits (437), Expect = 1e-42
Identities = 109/329 (33%), Positives = 162/329 (49%), Gaps = 45/329 (13%)
Query: 52 LNNYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNH 111
+ Y + EKLG+GT+ V+KG T VA+K I + E+ P TA RE+++LK + H
Sbjct: 189 METYIKLEKLGEGTYATVYKGRSKLTENLVALKEIRLEHEEGA-PCTAIREVSLLKDLKH 247
Query: 112 KNIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTG 171
NIV L +IV+ T K ++ Y+ DL
Sbjct: 248 ANIVTLHDIVH-------------------------------TDKSLTLVFEYLDKDLKQ 276
Query: 172 LLHNPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLAR 231
+ + M +VK + Q+L G+ Y H K LHRD+K N+LI+ KG +K+ADFGLAR
Sbjct: 277 YMDDCGNIMSMHNVKLFLYQILRGLAYCHRRKVLHRDLKPQNLLINEKGELKLADFGLAR 336
Query: 232 NYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFE 291
S P Y++ VVT WYR P+++LG Y T +D+WG+GC+F E
Sbjct: 337 AK--SVPT----------KTYSNEVVTLWYRPPDVLLGSSEYLTQIDMWGVGCIFFEMAS 384
Query: 292 KKPILQGQTDIDQGHVIFKLMGTPSMDEW-GLAYHLPGSELTKTNYKSTLQERFSKALNE 350
+P+ G T D+ H+IF+L+GTPS + W G++ + YK + L+
Sbjct: 385 GRPLFPGSTVEDELHLIFRLLGTPSQETWPGISSNEEFKNYNFPKYKPEPLINHAPRLDS 444
Query: 351 TGXXXXXXXXXXDPYKRVTAMKAKKHPFF 379
G + KRV+A +A KH +F
Sbjct: 445 EGIELIRKFLQYESKKRVSAEEAMKHVYF 473
>At4g22940 [D] KOG0600 Cdc2-related protein kinase
Length = 458
Score = 172 bits (437), Expect = 1e-42
Identities = 123/364 (33%), Positives = 171/364 (46%), Gaps = 51/364 (14%)
Query: 53 NNYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNHK 112
+++ ++E++G GTF +VFK L N+ VA+KRI REI IL++++H
Sbjct: 101 SHFEKQEQIGGGTFSKVFKARDLLRNKTVALKRIRFDINNSESIKCIAREIIILRKLDHP 160
Query: 113 NIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGL 172
N++KL ++ + H ++T ++I YM DL GL
Sbjct: 161 NVIKLEGLMLVD-----------------HDSST-----------LYLIFEYMEHDLLGL 192
Query: 173 LHNPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLARN 232
V F VK M QLL G+++ H N LHRD+K++N+LI+ GV+KIADFGLA
Sbjct: 193 SSLLGVHFSEPQVKCYMRQLLRGLDHCHTNHVLHRDMKSSNLLINGDGVLKIADFGLAT- 251
Query: 233 YYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFEK 292
+ P N T+ V T WYR PE++LG HY VD+W GCV E +
Sbjct: 252 -FFDPHN---------SVPLTTHVATLWYRPPELLLGASHYGIGVDLWSTGCVIGELYAG 301
Query: 293 KPILQGQTDIDQGHVIFKLMGTPSMDEW-GLAYHLPGSELTKTNYKSTLQERFSKALNET 351
KPIL G+ + DQ H IFKL G+PS D W L L Y S + E F K +
Sbjct: 302 KPILPGKNETDQLHKIFKLCGSPSDDYWTKLKLQLSTPLRPIYPYGSHIAETF-KQFPAS 360
Query: 352 GXXXXXXXXXXDPYKRVTAMKAKKHPFFFEEPLPNAQLTLPNEECHESDIKRYKSEMNES 411
DP R TA A K +F EPL C S + +Y S +
Sbjct: 361 VISLLETLLSIDPDFRGTAASALKSKYFKTEPL----------ACDPSCLPKYPSSKEIN 410
Query: 412 MSQR 415
+ R
Sbjct: 411 IKMR 414
>At1g03740 [D] KOG0600 Cdc2-related protein kinase
Length = 542
Score = 172 bits (437), Expect = 1e-42
Identities = 114/342 (33%), Positives = 164/342 (47%), Gaps = 44/342 (12%)
Query: 53 NNYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNHK 112
N + + EK+GQGT+ V++ L N+ VA+K++ REI +++R++H
Sbjct: 211 NTFEKLEKIGQGTYSSVYRARDLLHNKIVALKKVRFDLNDMESVKFMAREIIVMRRLDHP 270
Query: 113 NIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGL 172
N++KL ++ T+P +++ YM DL GL
Sbjct: 271 NVLKLEGLI-----------TAP------------------VSSSLYLVFEYMDHDLLGL 301
Query: 173 LHNPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLARN 232
P V+F VK M QLL G+ + H LHRDIK +N+LID KGV+KIADFGLA
Sbjct: 302 SSLPGVKFTEPQVKCYMRQLLSGLEHCHSRGVLHRDIKGSNLLIDSKGVLKIADFGLATF 361
Query: 233 YYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFEK 292
+ TS VVT WYR PE++LG HY VD+W GC+ E +
Sbjct: 362 F-----------DPAKSVSLTSHVVTLWYRPPELLLGASHYGVGVDLWSTGCILGELYAG 410
Query: 293 KPILQGQTDIDQGHVIFKLMGTPSMDEWGLAYHLPGSELTKT--NYKSTLQERFSKALNE 350
KPIL G+T+++Q H IFKL G+P+ + W LP S KT Y+ + E F K
Sbjct: 411 KPILPGKTEVEQLHKIFKLCGSPTENYW-RKQKLPSSAGFKTAIPYRRKVSEMF-KDFPA 468
Query: 351 TGXXXXXXXXXXDPYKRVTAMKAKKHPFFFEEPLPNAQLTLP 392
+ DP R +A +A + +F +P LP
Sbjct: 469 SVLSLLETLLSIDPDHRSSADRALESEYFKTKPFACDPSNLP 510
>Hs4502743 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 346
Score = 172 bits (435), Expect = 2e-42
Identities = 113/351 (32%), Positives = 173/351 (49%), Gaps = 47/351 (13%)
Query: 55 YREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILV--RAE-KDLFPITAQREITILKRMNH 111
Y + + LG+G F V+K TN+ VAIK+I + R+E KD TA REI +L+ ++H
Sbjct: 12 YEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSH 71
Query: 112 KNIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTG 171
NI+ L++ +S + ++ +M +DL
Sbjct: 72 PNIIGLLDAFGHKS-------------------------------NISLVFDFMETDLEV 100
Query: 172 LLHNPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLAR 231
++ + + + +K ML L+G+ Y+H + LHRD+K N+L+D GV+K+ADFGLA+
Sbjct: 101 IIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAK 160
Query: 232 NYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFE 291
++ GSP YT VVTRWYRAPE++ G R Y VD+W +GC+ AE
Sbjct: 161 SF-GSP-----------NRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLL 208
Query: 292 KKPILQGQTDIDQGHVIFKLMGTPSMDEWGLAYHLPGSELTKTNYKSTLQERFSKALNET 351
+ P L G +D+DQ IF+ +GTP+ ++W LP K+ L FS A ++
Sbjct: 209 RVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDL 268
Query: 352 GXXXXXXXXXXDPYKRVTAMKAKKHPFFFEEPLPNAQLTLPNEECHESDIK 402
+P R+TA +A K +F P P LP C +K
Sbjct: 269 -LDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLK 318
>Hs5453860 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 496
Score = 170 bits (431), Expect = 5e-42
Identities = 107/329 (32%), Positives = 162/329 (48%), Gaps = 45/329 (13%)
Query: 52 LNNYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNH 111
L Y + +KLG+GT+ V+KG T+ VA+K I + E+ P TA RE+++LK + H
Sbjct: 162 LETYIKLDKLGEGTYATVYKGKSKLTDNLVALKEIRLEHEEGA-PCTAIREVSLLKDLKH 220
Query: 112 KNIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTG 171
NIV L +I++ E K ++ Y+ DL
Sbjct: 221 ANIVTLHDIIHTE-------------------------------KSLTLVFEYLDKDLKQ 249
Query: 172 LLHNPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLAR 231
L + M +VK + QLL G+ Y H K LHRD+K N+LI+ +G +K+ADFGLAR
Sbjct: 250 YLDDCGNIINMHNVKLFLFQLLRGLAYCHRQKVLHRDLKPQNLLINERGELKLADFGLAR 309
Query: 232 NYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFE 291
S P Y++ VVT WYR P+I+LG Y+T +D+WG+GC+F E
Sbjct: 310 AK--SIPT----------KTYSNEVVTLWYRPPDILLGSTDYSTQIDMWGVGCIFYEMAT 357
Query: 292 KKPILQGQTDIDQGHVIFKLMGTPSMDEW-GLAYHLPGSELTKTNYKSTLQERFSKALNE 350
+P+ G T +Q H IF+++GTP+ + W G+ + Y++ + L+
Sbjct: 358 GRPLFPGSTVEEQLHFIFRILGTPTEETWPGILSNEEFKTYNYPKYRAEALLSHAPRLDS 417
Query: 351 TGXXXXXXXXXXDPYKRVTAMKAKKHPFF 379
G + R++A A KHPFF
Sbjct: 418 DGADLLTKLLQFEGRNRISAEDAMKHPFF 446
>Hs15011928 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 448
Score = 170 bits (431), Expect = 5e-42
Identities = 107/329 (32%), Positives = 162/329 (48%), Gaps = 45/329 (13%)
Query: 52 LNNYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNH 111
L Y + +KLG+GT+ V+KG T+ VA+K I + E+ P TA RE+++LK + H
Sbjct: 114 LETYIKLDKLGEGTYATVYKGKSKLTDNLVALKEIRLEHEEGA-PCTAIREVSLLKDLKH 172
Query: 112 KNIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTG 171
NIV L +I++ E K ++ Y+ DL
Sbjct: 173 ANIVTLHDIIHTE-------------------------------KSLTLVFEYLDKDLKQ 201
Query: 172 LLHNPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLAR 231
L + M +VK + QLL G+ Y H K LHRD+K N+LI+ +G +K+ADFGLAR
Sbjct: 202 YLDDCGNIINMHNVKLFLFQLLRGLAYCHRQKVLHRDLKPQNLLINERGELKLADFGLAR 261
Query: 232 NYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFE 291
S P Y++ VVT WYR P+I+LG Y+T +D+WG+GC+F E
Sbjct: 262 AK--SIPT----------KTYSNEVVTLWYRPPDILLGSTDYSTQIDMWGVGCIFYEMAT 309
Query: 292 KKPILQGQTDIDQGHVIFKLMGTPSMDEW-GLAYHLPGSELTKTNYKSTLQERFSKALNE 350
+P+ G T +Q H IF+++GTP+ + W G+ + Y++ + L+
Sbjct: 310 GRPLFPGSTVEEQLHFIFRILGTPTEETWPGILSNEEFKTYNYPKYRAEALLSHAPRLDS 369
Query: 351 TGXXXXXXXXXXDPYKRVTAMKAKKHPFF 379
G + R++A A KHPFF
Sbjct: 370 DGADLLTKLLQFEGRNRISAEDAMKHPFF 398
>YPL031c [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 305
Score = 169 bits (427), Expect = 2e-41
Identities = 105/335 (31%), Positives = 169/335 (50%), Gaps = 46/335 (13%)
Query: 53 NNYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNHK 112
+ +++ EKLG GT+ V+KG++ T VA+K + + +E+ P TA REI+++K + H+
Sbjct: 5 SQFKQLEKLGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGT-PSTAIREISLMKELKHE 63
Query: 113 NIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGL 172
NIV+L ++++ E+ + Y + T
Sbjct: 64 NIVRLYDVIHTENKLTLVFEFMDNDLKKYMDSRTVG------------------------ 99
Query: 173 LHNPR-VEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLAR 231
+ PR +E + VK QLL+G+ + H NK LHRD+K N+LI+ +G +K+ DFGLAR
Sbjct: 100 -NTPRGLELNL--VKYFQWQLLQGLAFCHENKILHRDLKPQNLLINKRGQLKLGDFGLAR 156
Query: 232 NYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFE 291
+ G P N ++S VVT WYRAP++++G R Y+T++DIW GC+ AE
Sbjct: 157 AF-GIPVNT-----------FSSEVVTLWYRAPDVLMGSRTYSTSIDIWSCGCILAEMIT 204
Query: 292 KKPILQGQTDIDQGHVIFKLMGTPSMDEWGLAYHLPG-----SELTKTNYKSTLQERFSK 346
KP+ G D +Q +IF +MGTP+ W LP + + + LQ +
Sbjct: 205 GKPLFPGTNDEEQLKLIFDIMGTPNESLWPSVTKLPKYNPNIQQRPPRDLRQVLQPHTKE 264
Query: 347 ALNETGXXXXXXXXXXDPYKRVTAMKAKKHPFFFE 381
L+ +P R++A +A HP+F E
Sbjct: 265 PLDGNLMDFLHGLLQLNPDMRLSAKQALHHPWFAE 299
>At1g57700 [D] KOG0600 Cdc2-related protein kinase
Length = 686
Score = 169 bits (427), Expect = 2e-41
Identities = 114/370 (30%), Positives = 176/370 (46%), Gaps = 54/370 (14%)
Query: 48 VTKFLNNYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILK 107
+ + +++ + E +GQGT+ V++ L TN+ VA+K++ REI IL+
Sbjct: 139 IPRSADSFEKLEMIGQGTYSSVYRARDLETNQIVALKKVRFANMDPESVRFMAREIIILR 198
Query: 108 RMNHKNIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVS 167
R+NH N++KL ++ ++ ++I YM
Sbjct: 199 RLNHPNVMKLEGLIISKA-----------------------------SGSMYLIFEYMDH 229
Query: 168 DLTGLLHNPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADF 227
DL GL P ++F A QLL G+ + H LHRDIK +N+L+D +KI DF
Sbjct: 230 DLAGLASTPGIKFSQAQ------QLLLGLEHCHSCGVLHRDIKCSNLLLDRNNNLKIGDF 283
Query: 228 GLARNYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFA 287
GL+ Y G K P TS VVT WYR PE++LG Y VD+W GC+ A
Sbjct: 284 GLSNFYRGQR---KQP--------LTSRVVTLWYRPPELLLGSTDYGVTVDLWSTGCILA 332
Query: 288 EFFEKKPILQGQTDIDQGHVIFKLMGTPSMDEWGLAYHLPGSELTKTN--YKSTLQERFS 345
E F KP+L G+T+++Q H IFKL G+PS + W + L + + K YK + + F
Sbjct: 333 ELFTGKPLLPGRTEVEQMHKIFKLCGSPSEEYWRRS-RLRHATIFKPQHPYKRCVADTF- 390
Query: 346 KALNETGXXXXXXXXXXDPYKRVTAMKAKKHPFFFEEPLPNAQLTLPNEECHESDIKRYK 405
K L + +P R TA A + FF +P P+ +LP + K +
Sbjct: 391 KDLPSSALALLEVLLAVEPDARGTASSALQSEFFTTKPFPSEPSSLPRYQPR----KEFD 446
Query: 406 SEMNESMSQR 415
+++ E ++R
Sbjct: 447 AKLREEEARR 456
>Hs4502741 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 326
Score = 168 bits (425), Expect = 3e-41
Identities = 114/385 (29%), Positives = 183/385 (46%), Gaps = 69/385 (17%)
Query: 47 GVTKFLNNYREEEKLGQGTFGEVFKGIHLGTN-RKVAIKRILVRAEKDLFPITAQREITI 105
G+ + Y ++G+G +G+VFK L R VA+KR+ V+ ++ P++ RE+ +
Sbjct: 5 GLCRADQQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIREVAV 64
Query: 106 LKRMN---HKNIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMIL 162
L+ + H N+V+L +D +TD + KL ++
Sbjct: 65 LRHLETFEHPNVVRL----FDVCTVSRTD----------------RETKLT------LVF 98
Query: 163 PYMVSDLTGLLHN-PRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGV 221
++ DLT L P +K++M QLL G++++H ++ +HRD+K NIL+ G
Sbjct: 99 EHVDQDLTTYLDKVPEPGVPTETIKDMMFQLLRGLDFLHSHRVVHRDLKPQNILVTSSGQ 158
Query: 222 VKIADFGLARNYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWG 281
+K+ADFGLAR Y TSVVVT WYRAPE++L Y T VD+W
Sbjct: 159 IKLADFGLARIY-------------SFQMALTSVVVTLWYRAPEVLL-QSSYATPVDLWS 204
Query: 282 IGCVFAEFFEKKPILQGQTDIDQGHVIFKLMGTPSMDEWGLAYHLPGSELTKTNYKSTLQ 341
+GC+FAE F +KP+ +G +D+DQ I ++G P ++W LP + +
Sbjct: 205 VGCIFAEMFRRKPLFRGSSDVDQLGKILDVIGLPGEEDWPRDVALPRQAFHSKSAQPI-- 262
Query: 342 ERFSKALNETGXXXXXXXXXXDPYKRVTAMKAKKHPFFFEEPLPNAQLTLPNEECHESDI 401
E+F ++E G +P KR++A A HP+F D+
Sbjct: 263 EKFVTDIDELGKDLLLKCLTFNPAKRISAYSALSHPYF-------------------QDL 303
Query: 402 KRYKSEMNESMSQRPPSAPTGHTST 426
+R K ++ S PPS T +T
Sbjct: 304 ERCKENLD---SHLPPSQNTSELNT 325
>Hs11496279 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 623
Score = 168 bits (425), Expect = 3e-41
Identities = 126/454 (27%), Positives = 198/454 (42%), Gaps = 78/454 (17%)
Query: 52 LNNYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNH 111
+N Y +LG GT+G V G + VAIKR + R RE+ LK++NH
Sbjct: 1 MNRYTTMRQLGDGTYGSVLMGKSNESGELVAIKR-MKRKFYSWDECMNLREVKSLKKLNH 59
Query: 112 KNIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTG 171
N++KL E++ + H + I YM +L
Sbjct: 60 ANVIKLKEVIREND-------------------------------HLYFIFEYMKENLYQ 88
Query: 172 LLHNPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLAR 231
L+ + F + ++NIM Q+L+G+ +IH + F HRD+K N+L +VKIADFGLAR
Sbjct: 89 LMKDRNKLFPESVIRNIMYQILQGLAFIHKHGFFHRDMKPENLLCMGPELVKIADFGLAR 148
Query: 232 NYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFE 291
PP YT V TRWYRAPE++L Y++ +D+W +G + AE +
Sbjct: 149 ELRSQPP-------------YTDYVSTRWYRAPEVLLRSSVYSSPIDVWAVGSIMAELYM 195
Query: 292 KKPILQGQTDIDQGHVIFKLMGTPSMDEWGLAYHLPGS------ELTKTNYKSTLQERFS 345
+P+ G +++D+ I +++GTP +W Y L S + N K+ + +
Sbjct: 196 LRPLFPGTSEVDEIFKICQVLGTPKKSDWPEGYQLASSMNFRFPQCVPINLKTLIPNASN 255
Query: 346 KALNETGXXXXXXXXXXDPYKRVTAMKAKKHPFFFEEPLPNAQLTLPNEECHESDIKRYK 405
+A+ DP KR TA +A KHP+F Q+ P+ ES K+
Sbjct: 256 EAIQ-----LMTEMLNWDPKKRPTASQALKHPYF-----QVGQVLGPSSNHLES--KQSL 303
Query: 406 SEMNESMSQRPPSAPTGHTSTDNSIRAVTGAAFPKEASIPKAP--RPEHIKSTIPAQPSA 463
++ + + +P + I V G PK + P P P+++ P + +
Sbjct: 304 NKQLQPLESKPSLVEVEPKPLPDIIDQVVGQPQPKTSQQPLQPIQPPQNLSVQQPPKQQS 363
Query: 464 SRYNGAATQNIPKEPIPTAPLPKGPKNSIPTGPN 497
+E P P KN +PT PN
Sbjct: 364 ------------QEKPPQTLFPSIVKN-MPTKPN 384
>SPCC16C4.11 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 288
Score = 167 bits (424), Expect = 4e-41
Identities = 106/328 (32%), Positives = 163/328 (49%), Gaps = 46/328 (14%)
Query: 54 NYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNHKN 113
NY+ EKLG+GT+ V+KG + T VA+K I + A++ P TA REI+++K + H N
Sbjct: 2 NYQRLEKLGEGTYAHVYKGQNRVTGEIVALKVIRIDADEGT-PSTAIREISLMKELRHPN 60
Query: 114 IVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGLL 173
I+ L +++ E+ ++ YM DL +
Sbjct: 61 IMSLSDVLQTENK-------------------------------LMLVFEYMEKDLKKYM 89
Query: 174 --HNPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLAR 231
+ + + VKN QLL+GI++ H N+ LHRD+K N+LI+ +G +K+ADFGLAR
Sbjct: 90 DTYGNQGALPPSQVKNFTQQLLKGISFCHENRVLHRDLKPQNLLINSRGELKLADFGLAR 149
Query: 232 NYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFE 291
+ G P N +++ VVT WYRAP+++LG R Y+T++DIW +GC+ AE
Sbjct: 150 SI-GIPVNT-----------FSNEVVTLWYRAPDVLLGSRVYSTSIDIWSVGCIMAEMAT 197
Query: 292 KKPILQGQTDIDQGHVIFKLMGTPSMDEWGLAYHLPGSELTKTNYKSTLQERFSKALNET 351
+P+ G + DQ IF+L+GTP+ W LP + T YK+ +
Sbjct: 198 GRPLFAGSNNEDQLLKIFRLLGTPTEQSWPGISLLPEYKPTFPIYKAQDLAYLFPTFDPL 257
Query: 352 GXXXXXXXXXXDPYKRVTAMKAKKHPFF 379
G P R T A +H +F
Sbjct: 258 GLDLLRRMLRLQPELRTTGQDALQHAWF 285
>Hs4826675 [UT] KOG0662 Cyclin-dependent kinase CDK5
Length = 292
Score = 167 bits (424), Expect = 4e-41
Identities = 100/329 (30%), Positives = 164/329 (49%), Gaps = 44/329 (13%)
Query: 52 LNNYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNH 111
+ Y + EK+G+GT+G VFK + T+ VA+KR+ + + + P +A REI +LK + H
Sbjct: 1 MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKH 60
Query: 112 KNIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTG 171
KNIV+L ++++ + K ++ + DL
Sbjct: 61 KNIVRLHDVLHSD-------------------------------KKLTLVFEFCDQDLKK 89
Query: 172 LLHNPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLAR 231
+ + VK+ + QLL+G+ + H LHRD+K N+LI+ G +K+ADFGLAR
Sbjct: 90 YFDSCNGDLDPEIVKSFLFQLLKGLGFCHSRNVLHRDLKPQNLLINRNGELKLADFGLAR 149
Query: 232 NYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFE 291
+G P Y++ VVT WYR P+++ G + Y+T++D+W GC+FAE
Sbjct: 150 -AFGIPVRC-----------YSAEVVTLWYRPPDVLFGAKLYSTSIDMWSAGCIFAELAN 197
Query: 292 K-KPILQGQTDIDQGHVIFKLMGTPSMDEWGLAYHLPGSELTKTNYKSTLQERFSKALNE 350
+P+ G DQ IF+L+GTP+ ++W LP + +T LN
Sbjct: 198 AGRPLFPGNDVDDQLKRIFRLLGTPTEEQWPSMTKLPDYKPYPMYPATTSLVNVVPKLNA 257
Query: 351 TGXXXXXXXXXXDPYKRVTAMKAKKHPFF 379
TG +P +R++A +A +HP+F
Sbjct: 258 TGRDLLQNLLKCNPVQRISAEEALQHPYF 286
>7290565 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 353
Score = 165 bits (417), Expect = 2e-40
Identities = 103/341 (30%), Positives = 164/341 (47%), Gaps = 47/341 (13%)
Query: 55 YREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDL---FPITAQREITILKRMNH 111
Y + LG+G F V+K TN+ VA+K+I + +D TA REI IL+ + H
Sbjct: 12 YAKLSFLGEGQFATVYKARDTVTNQIVAVKKIKKGSREDARDGINRTALREIKILQELQH 71
Query: 112 KNIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTG 171
+NI+ L+++ S + ++ +M +DL
Sbjct: 72 ENIIGLVDVFGQLS-------------------------------NVSLVFDFMDTDLEV 100
Query: 172 LLHNPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLAR 231
++ + ++ A++K + L+G+ Y+H N LHRD+K N+L++ G++KI DFGLA+
Sbjct: 101 IIKDNKIILTQANIKAYAIMTLKGLEYLHLNWILHRDLKPNNLLVNSDGILKIGDFGLAK 160
Query: 232 NYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFE 291
++ GSP + YT VVTRWYR+PE++ G R Y T VD+W +GC+ AE
Sbjct: 161 SF-GSPNRI-----------YTHHVVTRWYRSPELLFGARQYGTGVDMWAVGCILAELML 208
Query: 292 KKPILQGQTDIDQGHVIFKLMGTPSMDEWGLAYHLPGSELTKTNYKSTLQERFSKALNET 351
+ P + G +D+DQ IF +GTP+ EW L L N+ T + A
Sbjct: 209 RVPFMPGDSDLDQLTRIFSTLGTPTEAEWPHLSKL-HDYLQFRNFPGTPLDNIFTAAGND 267
Query: 352 GXXXXXXXXXXDPYKRVTAMKAKKHPFFFEEPLPNAQLTLP 392
+P +RV+ +A P+F +P P LP
Sbjct: 268 LIHLMQRLFAMNPLRRVSCREALSMPYFANKPAPTVGPKLP 308
>At2g38620 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 311
Score = 162 bits (409), Expect = 2e-39
Identities = 103/336 (30%), Positives = 173/336 (50%), Gaps = 41/336 (12%)
Query: 52 LNNYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNH 111
+ Y + EK+G+GT+G+V+K + T + VA+K+ + +++ P TA REI++L+ ++
Sbjct: 1 MEKYEKLEKVGEGTYGKVYKAMEKTTGKLVALKKTRLEMDEEGIPPTALREISLLQMLSQ 60
Query: 112 K-NIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLT 170
IV+L+ + + T S SP+ + +++ Y+ +DL
Sbjct: 61 SIYIVRLLCVEHVIQSKDSTVSHSPK-------------------SNLYLVFEYLDTDLK 101
Query: 171 GLLH------NPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDH-KGVVK 223
+ NPR + V+ M QL +G+ + H + LHRD+K N+L+D KG++K
Sbjct: 102 KFIDSHRKGSNPR-PLEASLVQRFMFQLFKGVAHCHSHGVLHRDLKPQNLLLDKDKGILK 160
Query: 224 IADFGLARNYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIG 283
IAD GL+R + P A YT +VT WYRAPE++LG HY+TAVDIW +G
Sbjct: 161 IADLGLSRAF-------TVPLKA-----YTHEIVTLWYRAPEVLLGSTHYSTAVDIWSVG 208
Query: 284 CVFAEFFEKKPILQGQTDIDQGHVIFKLMGTPSMDEWGLAYHLPGSELTKTNYKSTLQER 343
C+FAE ++ + G ++ Q IF+L+GTP+ +W L + ++ R
Sbjct: 209 CIFAEMIRRQALFPGDSEFQQLLHIFRLLGTPTEQQWPGVMALRDWHV-YPKWEPQDLSR 267
Query: 344 FSKALNETGXXXXXXXXXXDPYKRVTAMKAKKHPFF 379
+L+ G +P +R++A A HP+F
Sbjct: 268 AVPSLSPEGIDLLTQMLKYNPAERISAKAALDHPYF 303
>7297578 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 822
Score = 162 bits (409), Expect = 2e-39
Identities = 99/331 (29%), Positives = 159/331 (47%), Gaps = 50/331 (15%)
Query: 52 LNNYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNH 111
+N Y +LG GT+G V G T KVAIKR + R RE+ LK+++H
Sbjct: 1 MNRYITLTQLGDGTYGTVVLGQRKDTGEKVAIKR-MKRKYYSWEEAMNLREVKSLKKLSH 59
Query: 112 KNIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTG 171
NIVKL E++ + N+T + + YM +L
Sbjct: 60 PNIVKLKEVIRE--------------------NDT-----------LYFVFEYMKENLYQ 88
Query: 172 LLHNPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLAR 231
++ + ++K+I+ Q+L G+ ++H + F HRD+K N+L ++KIADFGLAR
Sbjct: 89 MIKDRDTHLPEPELKSILFQVLTGLAFMHRHGFFHRDLKPENLLCSGPDLIKIADFGLAR 148
Query: 232 NYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFE 291
PP +T V TRWYRAPE++L +Y + +D+W +GC+ AE +
Sbjct: 149 EIRSRPP-------------FTDYVSTRWYRAPEVLLHSTNYGSTIDLWAMGCIMAELYT 195
Query: 292 KKPILQGQTDIDQGHVIFKLMGTPSMDEWGLAYHLPGSELTKTNYKSTLQERFSKAL--- 348
+P+ G +++DQ I ++GTP D+W Y L + + Y ++ S +
Sbjct: 196 FRPLFPGSSEVDQLFKICSVLGTPDKDDWPDGYRL--ASMIHFRYPDCIKVPLSSVVSRC 253
Query: 349 NETGXXXXXXXXXXDPYKRVTAMKAKKHPFF 379
++ G DP KR TA ++ K+P+F
Sbjct: 254 SQNGLDLLEDMLAYDPDKRPTAQQSLKYPYF 284
>Hs16160923 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 472
Score = 161 bits (407), Expect = 3e-39
Identities = 106/335 (31%), Positives = 162/335 (47%), Gaps = 57/335 (17%)
Query: 52 LNNYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNH 111
L Y + +KLG+GT+ VFKG T VA+K I + E+ P TA RE+++LK + H
Sbjct: 139 LETYVKLDKLGEGTYATVFKGRSKLTENLVALKEIRLEHEEGA-PCTAIREVSLLKNLKH 197
Query: 112 KNIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTG 171
NIV L ++++ T + ++ Y+ SDL
Sbjct: 198 ANIVTLHDLIH-------------------------------TDRSLTLVFEYLDSDLKQ 226
Query: 172 LLHNPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLAR 231
L + M +VK M QLL G+ Y H K LHRD+K N+LI+ +G +K+ADFGLAR
Sbjct: 227 YLDHCGNLMSMHNVKIFMFQLLRGLAYCHHRKILHRDLKPQNLLINERGELKLADFGLAR 286
Query: 232 NYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFE 291
S P Y++ VVT WYR P+++LG Y+T +D+WG+GC+ E
Sbjct: 287 AK--SVPT----------KTYSNEVVTLWYRPPDVLLGSTEYSTPIDMWGVGCIHYEMAT 334
Query: 292 KKPILQGQTDIDQGHVIFKLMGTPSMDEWGLAYHLPG----SELTKTNYKSTLQE---RF 344
+P+ G T ++ H+IF+L+GTP+ + W PG SE ++ L +
Sbjct: 335 GRPLFPGSTVKEELHLIFRLLGTPTEETW------PGVTAFSEFRTYSFPCYLPQPLINH 388
Query: 345 SKALNETGXXXXXXXXXXDPYKRVTAMKAKKHPFF 379
+ L+ G + R++A A H +F
Sbjct: 389 APRLDTDGIHLLSSLLLYESKSRMSAEAALSHSYF 423
>CE21213 [UT] KOG0662 Cyclin-dependent kinase CDK5
Length = 292
Score = 160 bits (405), Expect = 6e-39
Identities = 97/327 (29%), Positives = 157/327 (47%), Gaps = 44/327 (13%)
Query: 54 NYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNHKN 113
NY + EK+G+GT+G VFK + + VA+KR+ + + + P +A REI IL+ + H+N
Sbjct: 3 NYDKMEKIGEGTYGTVFKARNKNSGEIVALKRVRLDDDDEGVPSSALREICILRELKHRN 62
Query: 114 IVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGLL 173
+V+L ++V+ E+ ++ Y DL
Sbjct: 63 VVRLYDVVHSENKLT-------------------------------LVFEYCDQDLKKFF 91
Query: 174 HNPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLARNY 233
+ +++MLQLL G+++ H + LHRD+K N+LI+ G +K+ADFGLAR
Sbjct: 92 DSLNGYMDAQTARSLMLQLLRGLSFCHAHHVLHRDLKPQNLLINTNGTLKLADFGLAR-A 150
Query: 234 YGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFEK- 292
+G P +++ VVT WYR P+++ G + Y T++D+W GC+FAE
Sbjct: 151 FGVPVRC-----------FSAEVVTLWYRPPDVLFGAKLYNTSIDMWSAGCIFAEISNAG 199
Query: 293 KPILQGQTDIDQGHVIFKLMGTPSMDEWGLAYHLPGSELTKTNYKSTLQERFSKALNETG 352
+P+ G DQ IFK +G+PS D W LP + + + + LN G
Sbjct: 200 RPLFPGADVDDQLKRIFKQLGSPSEDNWPSITQLPDYKPYPIYHPTLTWSQIVPNLNSRG 259
Query: 353 XXXXXXXXXXDPYKRVTAMKAKKHPFF 379
+P R+ A A +H +F
Sbjct: 260 RDLLQKLLVCNPAGRIDADAALRHAYF 286
>At3g05050 [D] KOG0600 Cdc2-related protein kinase
Length = 593
Score = 160 bits (405), Expect = 6e-39
Identities = 113/376 (30%), Positives = 171/376 (45%), Gaps = 48/376 (12%)
Query: 53 NNYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRA-EKDLFPITAQREITILKRMNH 111
+++ + +K+G GT+ V+K T VA+K++ E++ A REI IL+R++H
Sbjct: 136 DSFEKIDKIGSGTYSNVYKAKDSLTGNIVALKKVRCDVNERESLKFMA-REILILRRLDH 194
Query: 112 KNIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTG 171
N++KL +V T + S+ +++ YM DL G
Sbjct: 195 PNVIKLEGLV-----TSRMSSS------------------------LYLVFRYMDHDLAG 225
Query: 172 LLHNPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLAR 231
L +P ++F VK M QLL G+ + H LHRDIK +N+LID GV++I DFGLA
Sbjct: 226 LAASPEIKFTEQQVKCYMKQLLSGLEHCHNRGVLHRDIKGSNLLIDDGGVLRIGDFGLAT 285
Query: 232 NYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFE 291
+ A + T+ VVT WYR+PE++ G Y+ VD+W GC+ AE
Sbjct: 286 FF-----------DASKRQEMTNRVVTLWYRSPELLHGVVEYSVGVDLWSAGCILAELLA 334
Query: 292 KKPILQGQTDIDQGHVIFKLMGTPSMDEWGL----AYHLPGSELTKTNYKSTLQERFSKA 347
+ I+ G+ +++Q H I+KL G+PS + W + H YK ++E + K
Sbjct: 335 GRAIMPGRNEVEQLHRIYKLCGSPSEEYWKKIRLPSTHKHAHHKPLPQYKRRIREVY-KD 393
Query: 348 LNETGXXXXXXXXXXDPYKRVTAMKAKKHPFFFEEPLPNAQLTLPN-EECHESDIKRYKS 406
+ DP +R TA FF EPL LP E D KR
Sbjct: 394 FSPEALSLLDTLLALDPAERQTATDVLMSDFFTTEPLACQPSDLPKYPPSKEIDAKRRDE 453
Query: 407 EMNESMSQRPPSAPTG 422
E R +G
Sbjct: 454 EYRRQREARKAQGESG 469
>CE12408 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 527
Score = 160 bits (404), Expect = 7e-39
Identities = 98/329 (29%), Positives = 159/329 (47%), Gaps = 52/329 (15%)
Query: 55 YREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFP---ITAQREITILKRMNH 111
Y ++LG GTFGEV + T +VAIKR+ +K + + RE+ LK++NH
Sbjct: 45 YLMTKRLGDGTFGEVMLAKKIDTGDRVAIKRM----KKKFYSWEEAMSLREVKSLKKLNH 100
Query: 112 KNIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTG 171
NI+KL E++ + + + +M +L
Sbjct: 101 PNIIKLREVIRENDI-------------------------------LYFVFEFMQENLYE 129
Query: 172 LLHNPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLAR 231
L+ + F + ++NI+ Q+L+G+ ++H N F HRD+K NI+ + +VKIADFGLAR
Sbjct: 130 LMKDRDRYFPESVIRNIIYQVLQGLAFMHKNGFFHRDMKPENIMCNGTELVKIADFGLAR 189
Query: 232 NYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFE 291
PP YT V TRWYRAPEI+L Y + +D+W +GC+ AE +
Sbjct: 190 EIRSKPP-------------YTDYVSTRWYRAPEILLRSTSYNSPIDMWALGCIMAELYI 236
Query: 292 KKPILQGQTDIDQGHVIFKLMGTPSMDEWGLAYHLPGS-ELTKTNYKSTLQERFSKALNE 350
+P+ G +++DQ I ++GTP+ DEW Y L + +T E+ +++
Sbjct: 237 LRPLFPGTSEMDQLFKIISILGTPNKDEWPEGYQLASAMNFRFQQVVATPMEQVVNTISK 296
Query: 351 TGXXXXXXXXXXDPYKRVTAMKAKKHPFF 379
G +P KR A ++ ++ +F
Sbjct: 297 EGMKLMMDMMLWNPEKRPNANQSLRYKYF 325
>At1g76540 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 313
Score = 159 bits (403), Expect = 1e-38
Identities = 104/342 (30%), Positives = 171/342 (49%), Gaps = 54/342 (15%)
Query: 52 LNNYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRM-N 110
++ + + EK+G+GT+G+V++ T + VA+K+ + +++ P T REI+IL+ +
Sbjct: 11 MDAFEKLEKVGEGTYGKVYRAREKATGKIVALKKTRLHEDEEGVPSTTLREISILRMLAR 70
Query: 111 HKNIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLT 170
++V+L+++ S KT +++ YM +D+
Sbjct: 71 DPHVVRLMDVKQGLSKEGKTV--------------------------LYLVFEYMDTDVK 104
Query: 171 GLLHNPRV---EFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGV-VKIAD 226
+ + R +K++M QL +G+ + H + LHRD+K N+L+D K + +KIAD
Sbjct: 105 KFIRSFRSTGKNIPTQTIKSLMYQLCKGMAFCHGHGILHRDLKPHNLLMDPKTMRLKIAD 164
Query: 227 FGLARNYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVF 286
GLAR + KYT ++T WYRAPE++LG HY+TAVD+W +GC+F
Sbjct: 165 LGLARAF------------TLPMKKYTHEILTLWYRAPEVLLGATHYSTAVDMWSVGCIF 212
Query: 287 AEFFEKKPILQGQTDIDQGHVIFKLMGTPSMDEWGLAYHLPGSELTKT--NYKSTLQERF 344
AE + I QG +++ Q IFKL GTP+ + W PG K Y
Sbjct: 213 AELVTNQAIFQGDSELQQLLHIFKLFGTPNEEMW------PGVSTLKNWHEYPQWKPSTL 266
Query: 345 SKA---LNETGXXXXXXXXXXDPYKRVTAMKAKKHPFFFEEP 383
S A L+E G +P KR++A A +HP+F + P
Sbjct: 267 SSAVPNLDEAGVDLLSKMLQYEPAKRISAKMAMEHPYFDDLP 308
>7292375 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 509
Score = 159 bits (402), Expect = 1e-38
Identities = 110/345 (31%), Positives = 166/345 (47%), Gaps = 50/345 (14%)
Query: 55 YREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNHKNI 114
Y + E LG+G++ V+KG T ++VA+K I ++ E+ P TA RE ++LK + H NI
Sbjct: 192 YVKLEPLGEGSYATVYKGFSKLTYQRVALKEIRLQEEEGA-PFTAIREASLLKELKHSNI 250
Query: 115 VKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGLLH 174
V L +IV+ T + + Y+ +DL+ +
Sbjct: 251 VTLHDIVH-------------------------------TRETLTFVFEYVNTDLSQYME 279
Query: 175 NPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLARNYY 234
+V+ + QLL G++Y H + LHRD+K N+LI G +K+ADFGLAR
Sbjct: 280 KHPGGLDHRNVRLFLFQLLRGLSYCHKRRVLHRDVKPQNLLISDCGELKLADFGLARAK- 338
Query: 235 GSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFEKKP 294
S P+ Y+ VVT WYR P+++LG Y+T++D+WG+GC+F E P
Sbjct: 339 -SVPS----------HTYSHEVVTLWYRPPDVLLGSTEYSTSLDMWGVGCIFVEMVTGMP 387
Query: 295 ILQGQTD-IDQGHVIFKLMGTPSMDEWGLAYHLPGSELTKTNY--KSTLQERFSKALN-E 350
G D DQ IFKL+GTP+ D W H PG + K + L F + +
Sbjct: 388 TFPGIRDTYDQLDKIFKLLGTPTEDTWPGVTHFPGYKPHKLGFYRPRKLGHNFPRLYDII 447
Query: 351 TGXXXXXXXXXXDPYKRVTAMKAKKHPFFFEEPLPNAQLTLPNEE 395
G +P +R+ A A +HP+F + LP LP+ E
Sbjct: 448 EGETIANGFLQLNPEQRLGADDALQHPYFAQ--LPKKLYELPDGE 490
>ECU02g1450 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 308
Score = 158 bits (399), Expect = 3e-38
Identities = 114/355 (32%), Positives = 165/355 (46%), Gaps = 62/355 (17%)
Query: 52 LNNYREEEKLGQGTFGEVFKG----------IHLGTNRK---VAIKRILVRAEKDLFPIT 98
+ Y E +LG+GT+ ++ G + GT + VAIK+I I+
Sbjct: 1 MKTYIRERRLGEGTYAVIYLGYRALPQDKPLVSSGTRIEDVPVAIKKIKPTKYTQGHEIS 60
Query: 99 AQREITILKRMNHKNIVKLIE-IVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKH 157
A REI LKR++ K +V+LI+ VYD K
Sbjct: 61 AIREIKSLKRIDSKYVVRLIDTFVYD--------------------------------KC 88
Query: 158 FFMILPYMVSDLTGLLHNPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILID 217
++L Y+ ++L ++ N D+K +L +L G+ H +HRDIK NILI
Sbjct: 89 VHIVLEYVETNLENVIRNSDKIIMPGDIKAWILMVLRGVYECHRLFIIHRDIKPNNILIT 148
Query: 218 HKGVVKIADFGLARNYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAV 277
+G+VK+ADFGL R G G + T VTRWYRAPE+++G R Y + V
Sbjct: 149 SEGMVKLADFGLTR---------------GIGNRMTPQAVTRWYRAPELLMGSRDYGSPV 193
Query: 278 DIWGIGCVFAEFFEKKPILQGQTDIDQGHVIFKLMGTPSMDEWGLAYHLPGSELTKTNYK 337
D+W +GCVFAE F + P+ G TDI Q +IF+ +GTP EW LP + K
Sbjct: 194 DMWSVGCVFAELFLRVPLFAGDTDIQQLDMIFRALGTPVEREWPGVSTLPEFLDFQQYPK 253
Query: 338 STLQERFSKALNETGXXXXXXXXXXDPYKRVTAMKAKKHPFFFEEPLPNAQLTLP 392
++L FS A ++ +P R++ A KHP+F P P LP
Sbjct: 254 ASLNGLFSAASSD-ALDLLEKLLTLNPCNRISCDDAIKHPYFKSSPPPTPIGKLP 307
>ECU08g1920 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 296
Score = 156 bits (395), Expect = 8e-38
Identities = 105/346 (30%), Positives = 160/346 (45%), Gaps = 71/346 (20%)
Query: 54 NYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNHKN 113
++++ EK+G+GT+G V+K TNR VA+K+I + E + P T REI +LK + H
Sbjct: 4 SFQKLEKIGEGTYGVVYKARERNTNRVVALKKIRLENENEGIPATTIREILLLKNLKHST 63
Query: 114 IVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGLL 173
IV+L +++Y N K+ +++ Y+ DL L
Sbjct: 64 IVELSDVIY-------------------------NNNKM------YLVFEYVELDLRRYL 92
Query: 174 HNPRVEFGMAD---VKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLA 230
E + + V+ + QLL + Y H HRD+K NIL+D K +K+ADFGL
Sbjct: 93 DRMSDEGRLVEEGFVRKMSQQLLTAMEYCHSRNIFHRDLKPQNILVDPKENIKLADFGLG 152
Query: 231 RNYYGSPPNLKYPGGAGSGAK-YTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEF 289
R AG + YT+ VVT WYR PE++LG ++Y +VD+W C+ AE
Sbjct: 153 R-------------AAGIPLRTYTTEVVTLWYRPPELLLGCKYYDASVDVWSAACIMAEV 199
Query: 290 FEKKPILQGQTDIDQGHVIFKLMGTPSMDEWGLAYHLPGSEL---------TKTNYKS-- 338
+P G ++IDQ IFK++GTP+ W + P ++ KT ++
Sbjct: 200 VLMRPFFPGDSEIDQLFRIFKVLGTPNNSRWSNVENFPNYKVEFPVWDPVDLKTIFRGDP 259
Query: 339 TLQERFSKALNETGXXXXXXXXXXDPYKRVTAMKAKKHPFFFEEPL 384
+ SK L DP R+TA H +F PL
Sbjct: 260 DFVDLISKMLE------------YDPKMRMTAKNGLSHKYFEGMPL 293
>At1g20930 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 315
Score = 155 bits (392), Expect = 2e-37
Identities = 104/353 (29%), Positives = 174/353 (48%), Gaps = 54/353 (15%)
Query: 41 ENEKVYGVTKFLNNYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQ 100
+N V + + + EK+G+GT+G+V++ T VA+K+ + +++ P T
Sbjct: 2 DNNGVKPAVSAMEAFEKLEKVGEGTYGKVYRAREKATGMIVALKKTRLHEDEEGVPPTTL 61
Query: 101 REITILKRM-NHKNIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFF 159
REI+IL+ + +IV+L+++ + KT +
Sbjct: 62 REISILRMLARDPHIVRLMDVKQGINKEGKTV--------------------------LY 95
Query: 160 MILPYMVSDLTGLLHNPRV---EFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILI 216
++ Y+ +DL + + R VK +M QL +G+ + H + LHRD+K N+L+
Sbjct: 96 LVFEYVDTDLKKFIRSFRQAGQNIPQNTVKCLMYQLCKGMAFCHGHGVLHRDLKPHNLLM 155
Query: 217 DHKGV-VKIADFGLARNYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTT 275
D K + +KIAD GLAR + KYT ++T WYRAPE++LG HY+T
Sbjct: 156 DRKTMTLKIADLGLARAF------------TLPMKKYTHEILTLWYRAPEVLLGATHYST 203
Query: 276 AVDIWGIGCVFAEFFEKKPILQGQTDIDQGHVIFKLMGTPSMDEWGLAYHLPGSELTKTN 335
VD+W +GC+FAE K+ I G +++ Q IF+L+GTP+ + W PG K
Sbjct: 204 GVDMWSVGCIFAELVTKQAIFAGDSELQQLLRIFRLLGTPNEEVW------PGVSKLKDW 257
Query: 336 YKSTLQERFSKA-----LNETGXXXXXXXXXXDPYKRVTAMKAKKHPFFFEEP 383
++ + S + L+E G +P KR++A KA +HP+F + P
Sbjct: 258 HEYPQWKPLSLSTAVPNLDEAGLDLLSKMLEYEPAKRISAKKAMEHPYFDDLP 310
>Hs4506785 [T] KOG0660 Mitogen-activated protein kinase
Length = 367
Score = 154 bits (389), Expect = 4e-37
Identities = 101/333 (30%), Positives = 162/333 (48%), Gaps = 56/333 (16%)
Query: 55 YREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNHKNI 114
YR+ + +G G +G V + T KVAIK++ + +LF A RE+ +LK M H+N+
Sbjct: 27 YRDLQPVGSGAYGAVCSAVDGRTGAKVAIKKLYRPFQSELFAKRAYRELRLLKHMRHENV 86
Query: 115 VKLIEIVY-DESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGLL 173
+ L+++ DE+ TD F++++P+M +DL L+
Sbjct: 87 IGLLDVFTPDETLDDFTD--------------------------FYLVMPFMGTDLGKLM 120
Query: 174 HNPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLARNY 233
+ ++ G ++ ++ Q+L+G+ YIH +HRD+K N+ ++ +KI DFGLAR
Sbjct: 121 KHEKL--GEDRIQFLVYQMLKGLRYIHAAGIIHRDLKPGNLAVNEDCELKILDFGLARQ- 177
Query: 234 YGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFEKK 293
+ ++ T VVTRWYRAPE++L YT VDIW +GC+ AE K
Sbjct: 178 --------------ADSEMTGYVVTRWYRAPEVILNWMRYTQTVDIWSVGCIMAEMITGK 223
Query: 294 PILQGQTDIDQGHVIFKLMGTP------SMDEWGLAYHLPG-SELTKTNYKSTLQERFSK 346
+ +G +DQ I K+ GTP + ++ G EL K ++ S L
Sbjct: 224 TLFKGSDHLDQLKEIMKVTGTPPAEFVQRLQSDEAKNNMKGLPELEKKDFASILTNASPL 283
Query: 347 ALNETGXXXXXXXXXXDPYKRVTAMKAKKHPFF 379
A+N D +RVTA +A HP+F
Sbjct: 284 AVN-----LLEKMLVLDAEQRVTAGEALAHPYF 311
>At3g54180 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 309
Score = 153 bits (387), Expect = 7e-37
Identities = 97/340 (28%), Positives = 170/340 (49%), Gaps = 51/340 (15%)
Query: 52 LNNYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNH 111
+ Y + EK+G+GT+G+V+K + GT + VA+K+ + +++ P TA REI++L+ ++
Sbjct: 1 MEKYEKLEKVGEGTYGKVYKAMEKGTGKLVALKKTRLEMDEEGIPPTALREISLLQMLST 60
Query: 112 K-NIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLT 170
+V+L+ + + P+ K+ ST + +++ Y+ +DL
Sbjct: 61 SIYVVRLLCVEHVHQPSTKSQSTK---------------------SNLYLVFEYLDTDLK 99
Query: 171 GLLHNPRVEFGMAD-----VKNIMLQLLEGINYIHCNKFLHRDIKTANIL-IDHKGVVKI 224
+ + R ++ +M QL +G+ + H + LHRD+K N+L + K ++KI
Sbjct: 100 KFIDSYRKGPNPKPLEPFLIQKLMFQLCKGVAHCHSHGVLHRDLKPQNLLLVKDKELLKI 159
Query: 225 ADFGLARNYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGC 284
AD GL R + LK YT +VT WYRAPE++LG HY+T VD+W +GC
Sbjct: 160 ADLGLGRAF---TVPLK---------SYTHEIVTLWYRAPEVLLGSTHYSTGVDMWSVGC 207
Query: 285 VFAEFFEKKPILQGQTDIDQGHVIFKLMGTPSMDEWGLAYHLPGSELTKTNYKSTLQERF 344
+FAE ++ + G ++ Q IF+L+GTP+ +W PG + + E
Sbjct: 208 IFAEMVRRQALFPGDSEFQQLLHIFRLLGTPTEQQW------PGVSTLRDWHVYPKWEPQ 261
Query: 345 S-----KALNETGXXXXXXXXXXDPYKRVTAMKAKKHPFF 379
+L+ G +P +R++A A HP+F
Sbjct: 262 DLTLAVPSLSPQGVDLLTKMLKYNPAERISAKTALDHPYF 301
>CE29612 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 426
Score = 152 bits (385), Expect = 1e-36
Identities = 105/340 (30%), Positives = 158/340 (45%), Gaps = 56/340 (16%)
Query: 55 YREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNHKNI 114
Y+ +KLG+G++ V+K VA+K I ++ ++ L P TA RE ++L+ + H NI
Sbjct: 108 YKRIDKLGEGSYATVYKCESKLDGSIVALKEIKLQFQEGL-PFTAIREASLLRNLRHANI 166
Query: 115 VKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGLLH 174
V L +I Y Q +T + YM DL+ L
Sbjct: 167 VSLHDIFY--------------------------QHHQLT-----FVFEYMKMDLSKYLE 195
Query: 175 NPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLARNYY 234
D+K ++ QLL G+++ H K LHRD+K N+L+D GV+K+ADFGLAR
Sbjct: 196 QNVYGLDSIDIKLLLFQLLRGLDFCHRKKILHRDLKPQNLLLDEDGVLKLADFGLAR--- 252
Query: 235 GSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFEKKP 294
+ Y+ VVT WYR P++++G Y+T++D+WG+GC+FAE
Sbjct: 253 ---------AKSVPSRTYSHEVVTLWYRPPDVLMGSTDYSTSLDMWGVGCIFAEICTGAA 303
Query: 295 ILQGQTDI------DQGHVIFKLMGTPSMDEWGLAYHLPG-SELTKTNYKS----TLQER 343
+ G D DQ +IF + GTP +W LPG + Y+ +
Sbjct: 304 LFPGSKDSHYPGTKDQLDMIFSIRGTPDEKKWPEVKTLPGYTPELFPRYRELSFIAVNPM 363
Query: 344 FSKALNETGXXXXXXXXXXDPYKRVTAMKAKKHPFFFEEP 383
F+K L +TG P RV+A A HP+F P
Sbjct: 364 FTKIL-KTGQELLGMLLQLRPESRVSAASAMLHPYFASFP 402
>Hs6912584 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 451
Score = 152 bits (383), Expect = 2e-36
Identities = 114/384 (29%), Positives = 180/384 (46%), Gaps = 50/384 (13%)
Query: 6 KKPASLKYKIGKVKQIPTVVKDDKTGLEYIQVQSRENEKVYGVTKF--LNNYREEEKLGQ 63
+KPA+ ++ K TG E +V+ + KF ++Y + EKLG+
Sbjct: 66 EKPANQVKRVHSENNACINFKTSSTGKESPKVRRHSSPSSPTSPKFGKADSYEKLEKLGE 125
Query: 64 GTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNHKNIVKLIEIVYD 123
G++ V+KG + VA+K I ++ E+ P TA RE ++LK + H NIV L +I++
Sbjct: 126 GSYATVYKGKSKVNGKLVALKVIRLQEEEGT-PFTAIREASLLKGLKHANIVLLHDIIH- 183
Query: 124 ESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGLLHNPRVEFGMA 183
T + ++ Y+ +DL +
Sbjct: 184 ------------------------------TKETLTLVFEYVHTDLCQYMDKHPGGLHPD 213
Query: 184 DVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLARNYYGSPPNLKYP 243
+VK + QLL G++YIH LHRD+K N+LI G +K+ADFGLAR S P+
Sbjct: 214 NVKLFLFQLLRGLSYIHQRYILHRDLKPQNLLISDTGELKLADFGLARAK--SVPS---- 267
Query: 244 GGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFEKKPILQGQTDI- 302
Y++ VVT WYR P+++LG Y+T +D+WG+GC+F E + G DI
Sbjct: 268 ------HTYSNEVVTLWYRPPDVLLGSTEYSTCLDMWGVGCIFVEMIQGVAAFPGMKDIQ 321
Query: 303 DQGHVIFKLMGTPSMDEWGLAYHLPGSELTK-TNYKS-TLQERFSK-ALNETGXXXXXXX 359
DQ IF ++GTP+ D W + LP + + T Y S L++ ++K +
Sbjct: 322 DQLERIFLVLGTPNEDTWPGVHSLPHFKPERFTLYSSKNLRQAWNKLSYVNHAEDLASKL 381
Query: 360 XXXDPYKRVTAMKAKKHPFFFEEP 383
P R++A A H +F + P
Sbjct: 382 LQCSPKNRLSAQAALSHEYFSDLP 405
>Hs21040235 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 384
Score = 151 bits (381), Expect = 3e-36
Identities = 110/349 (31%), Positives = 164/349 (46%), Gaps = 54/349 (15%)
Query: 53 NNYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNHK 112
++Y EKLG+G++ V+KGI + VA+K I + AE+ + P TA RE ++LK + H
Sbjct: 50 SSYLNLEKLGEGSYATVYKGISRINGQLVALKVISMNAEEGV-PFTAIREASLLKGLKHA 108
Query: 113 NIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGL 172
NIV L +I++ T + + YM +DL
Sbjct: 109 NIVLLHDIIH-------------------------------TKETLTFVFEYMHTDLAQY 137
Query: 173 LHNPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLARN 232
+ +V+ M QLL G+ YIH LHRD+K N+LI H G +K+ADFGLAR
Sbjct: 138 MSQHPGGLHPHNVRLFMFQLLRGLAYIHHQHVLHRDLKPQNLLISHLGELKLADFGLARA 197
Query: 233 YYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFEK 292
S P+ Y+S VVT WYR P+ +LG Y++ +DIWG GC+F E F+
Sbjct: 198 K--SIPS----------QTYSSEVVTLWYRPPDALLGATEYSSELDIWGAGCIFIEMFQG 245
Query: 293 KPILQGQTDI-DQGHVIFKLMGTPSMDEWGLAYHLPGSE-----LTKTNYKSTLQERFSK 346
+P+ G ++I +Q I++++G P+ D W LP L + R +
Sbjct: 246 QPLFPGVSNILEQLEKIWEVLGVPTEDTWPGVSKLPNYNPEWFPLPTPRSLHVVWNRLGR 305
Query: 347 ALNETGXXXXXXXXXXDPYKRVTAMKAKKHPFFFEEPLPNAQLTLPNEE 395
P RV+A +A H +F LP+ LP+EE
Sbjct: 306 V--PEAEDLASQMLKGFPRDRVSAQEALVHDYF--SALPSQLYQLPDEE 350
>Hs4506085 [T] KOG0660 Mitogen-activated protein kinase
Length = 365
Score = 150 bits (378), Expect = 8e-36
Identities = 100/355 (28%), Positives = 168/355 (47%), Gaps = 57/355 (16%)
Query: 55 YREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNHKNI 114
Y +G G +G V I + KVAIK++ + ++F A RE+ +LK M H+N+
Sbjct: 25 YVSPTHVGSGAYGSVCSAIDKRSGEKVAIKKLSRPFQSEIFAKRAYRELLLLKHMQHENV 84
Query: 115 VKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGLLH 174
+ L+++ T ++S R N++ F++++P+M +DL ++
Sbjct: 85 IGLLDVF--------TPASSLR---NFYD--------------FYLVMPFMQTDLQKIMG 119
Query: 175 NPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLARNYY 234
+EF ++ ++ Q+L+G+ YIH +HRD+K N+ ++ +KI DFGLAR+
Sbjct: 120 ---MEFSEEKIQYLVYQMLKGLKYIHSAGVVHRDLKPGNLAVNEDCELKILDFGLARH-- 174
Query: 235 GSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFEKKP 294
+ A+ T VVTRWYRAPE++L HY VDIW +GC+ AE K
Sbjct: 175 -------------ADAEMTGYVVTRWYRAPEVILSWMHYNQTVDIWSVGCIMAEMLTGKT 221
Query: 295 ILQGQTDIDQGHVIFKLMGTPSMDEWGLAYHLPGSELTKTNYKSTLQERFSKALNET--- 351
+ +G+ +DQ I K+ G P G + ++ +Y +L + K +
Sbjct: 222 LFKGKDYLDQLTQILKVTGVP-----GTEFVQKLNDKAAKSYIQSLPQTPRKDFTQLFPR 276
Query: 352 ----GXXXXXXXXXXDPYKRVTAMKAKKHPFF--FEEPLPNAQLTLPNEECHESD 400
D KR+TA +A HPFF F +P + P ++ E +
Sbjct: 277 ASPQAADLLEKMLELDVDKRLTAAQALTHPFFEPFRDPEEETEAQQPFDDSLEHE 331
>Hs4502745 [K] KOG0666 Cyclin C-dependent kinase CDK8
Length = 464
Score = 149 bits (376), Expect = 1e-35
Identities = 126/432 (29%), Positives = 190/432 (43%), Gaps = 89/432 (20%)
Query: 39 SRENEKVYGVTKFLNNYREEEKLGQGTFGEVFKGIHLG--TNRKVAIKRILVRAEKDLFP 96
S E E+V + ++ E K+G+GT+G V+K ++ A+K+I E
Sbjct: 10 SSERERVEDLFEY-----EGCKVGRGTYGHVYKAKRKDGKDDKDYALKQI----EGTGIS 60
Query: 97 ITAQREITILKRMNHKNIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGK 156
++A REI +L+ + H N++ L ++ + +
Sbjct: 61 MSACREIALLRELKHPNVISLQKVFLSHAD-----------------------------R 91
Query: 157 HFFMILPYMVSDLTGLLHNPR--------VEFGMADVKNIMLQLLEGINYIHCNKFLHRD 208
+++ Y DL ++ R V+ VK+++ Q+L+GI+Y+H N LHRD
Sbjct: 92 KVWLLFDYAEHDLWHIIKFHRASKANKKPVQLPRGMVKSLLYQILDGIHYLHANWVLHRD 151
Query: 209 IKTANILI----DHKGVVKIADFGLARNYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAP 264
+K ANIL+ +G VKIAD G AR + L A VVVT WYRAP
Sbjct: 152 LKPANILVMGEGPERGRVKIADMGFARLFNSPLKPL---------ADLDPVVVTFWYRAP 202
Query: 265 EIVLGDRHYTTAVDIWGIGCVFAEFFEKKPILQ-GQTDI--------DQGHVIFKLMGTP 315
E++LG RHYT A+DIW IGC+FAE +PI Q DI DQ IF +MG P
Sbjct: 203 ELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPYHHDQLDRIFNVMGFP 262
Query: 316 SMDEWGLAYHLP-GSELTKTNYKST--------LQERFSKALNETGXXXXXXXXXXDPYK 366
+ +W +P S L K ++T E+ + DP K
Sbjct: 263 ADKDWEDIKKMPEHSTLMKDFRRNTYTNCSLIKYMEKHKVKPDSKAFHLLQKLLTMDPIK 322
Query: 367 RVTAMKAKKHPFFFEEPLPNA------QLTLPNEEC---HESDIKRYKSEMNESMSQRPP 417
R+T+ +A + P+F E+PLP + Q+ P E E D K K +
Sbjct: 323 RITSEQAMQDPYFLEDPLPTSDVFAGCQIPYPKREFLTEEEPDDKGDKKNQQQQQGNNHT 382
Query: 418 SAPTGHTSTDNS 429
+ TGH +S
Sbjct: 383 NG-TGHPGNQDS 393
>CE29073 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 700
Score = 149 bits (376), Expect = 1e-35
Identities = 98/328 (29%), Positives = 158/328 (47%), Gaps = 45/328 (13%)
Query: 52 LNNYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNH 111
L Y + +KLG+GT+ VF+G + TN+ VA+K I + E+ P TA RE+++L+ + H
Sbjct: 358 LETYEKLDKLGEGTYATVFRGRSILTNKFVALKEIRLEQEEGA-PCTAIREVSLLRNLRH 416
Query: 112 KNIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTG 171
N+V L +I++ + +L+T ++ Y+ DL
Sbjct: 417 ANVVTLHDIIHTD--------------------------RLLT-----LVFEYVDRDLKQ 445
Query: 172 LLHNPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLAR 231
+ + M +++ + QLL G+ Y H + LHRD+K N+LI KG +K+ADFGLAR
Sbjct: 446 YMDSCNNAMQMNNIRLFLYQLLRGLAYCHQRRVLHRDLKPQNLLITAKGELKLADFGLAR 505
Query: 232 NYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFE 291
S P Y++ VVT WYR P+++LG Y+T +D+WG+GC+ E
Sbjct: 506 AK--SVPT----------KTYSNEVVTLWYRPPDVLLGSTDYSTHIDMWGVGCILFEMIA 553
Query: 292 KKPILQGQTDIDQGHVIFKLMGTPSMDEWGLAYHLPG-SELTKTNYKSTLQERFSKALNE 350
+ + G T +Q +IF+ +G+P D P +Y R ++
Sbjct: 554 GRALFPGGTPTEQLGLIFRTLGSPRPDRHPTICEKPTFYPYANRHYNPDPLCRQIPRIDA 613
Query: 351 TGXXXXXXXXXXDPYKRVTAMKAKKHPF 378
G + RV+A +A KHPF
Sbjct: 614 HGFELLMKFLQYEGKDRVSAAEAVKHPF 641
>CE06779 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 577
Score = 149 bits (376), Expect = 1e-35
Identities = 98/328 (29%), Positives = 158/328 (47%), Gaps = 45/328 (13%)
Query: 52 LNNYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNH 111
L Y + +KLG+GT+ VF+G + TN+ VA+K I + E+ P TA RE+++L+ + H
Sbjct: 235 LETYEKLDKLGEGTYATVFRGRSILTNKFVALKEIRLEQEEGA-PCTAIREVSLLRNLRH 293
Query: 112 KNIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTG 171
N+V L +I++ + +L+T ++ Y+ DL
Sbjct: 294 ANVVTLHDIIHTD--------------------------RLLT-----LVFEYVDRDLKQ 322
Query: 172 LLHNPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLAR 231
+ + M +++ + QLL G+ Y H + LHRD+K N+LI KG +K+ADFGLAR
Sbjct: 323 YMDSCNNAMQMNNIRLFLYQLLRGLAYCHQRRVLHRDLKPQNLLITAKGELKLADFGLAR 382
Query: 232 NYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFE 291
S P Y++ VVT WYR P+++LG Y+T +D+WG+GC+ E
Sbjct: 383 AK--SVPT----------KTYSNEVVTLWYRPPDVLLGSTDYSTHIDMWGVGCILFEMIA 430
Query: 292 KKPILQGQTDIDQGHVIFKLMGTPSMDEWGLAYHLPG-SELTKTNYKSTLQERFSKALNE 350
+ + G T +Q +IF+ +G+P D P +Y R ++
Sbjct: 431 GRALFPGGTPTEQLGLIFRTLGSPRPDRHPTICEKPTFYPYANRHYNPDPLCRQIPRIDA 490
Query: 351 TGXXXXXXXXXXDPYKRVTAMKAKKHPF 378
G + RV+A +A KHPF
Sbjct: 491 HGFELLMKFLQYEGKDRVSAAEAVKHPF 518
>At5g45430 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 530
Score = 149 bits (376), Expect = 1e-35
Identities = 126/459 (27%), Positives = 199/459 (42%), Gaps = 97/459 (21%)
Query: 52 LNNYREEEKLGQGTFGEVFKGIHLGTNR--------KVAIKRILVRAEKDLFP---ITAQ 100
+ Y +++G GTFG V++ ++ TN +VAIKR+ +K F
Sbjct: 1 MERYTLLKEVGDGTFGNVWRAVNKQTNEVGTEVFYVQVAIKRM----KKKYFSWEECVNL 56
Query: 101 REITILKRMNHKNIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFM 160
RE+ L RMNH NIVKL E++ + +
Sbjct: 57 REVKSLSRMNHPNIVKLKEVIRENDI-------------------------------LYF 85
Query: 161 ILPYMVSDLTGLLHNPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKG 220
+ YM +L L+ + F +D++N Q+ +G++Y+H + HRD+K N+L+ K
Sbjct: 86 VFEYMECNLYQLMKDRPKHFAESDIRNWCFQVFQGLSYMHQRGYFHRDLKPENLLVS-KD 144
Query: 221 VVKIADFGLARNYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIW 280
V+KIAD GLAR SPP YT V TRWYRAPE++L YT+ VD+W
Sbjct: 145 VIKIADLGLAREIDSSPP-------------YTEYVSTRWYRAPEVLLQSYVYTSKVDMW 191
Query: 281 GIGCVFAEFFEKKPILQGQTDIDQGHVIFKLMGTPSMDEW--------GLAYHLPGSELT 332
+G + AE +P+ G ++ D+ + I ++G+P+ + W + Y P +
Sbjct: 192 AMGAIMAELLSLRPLFPGASEADEIYKICSVIGSPTEETWLEGLNLASVINYQFP--QFP 249
Query: 333 KTNYKSTLQERFSKALNETGXXXXXXXXXXDPYKRVTAMKAKKHPFF----FEEPLPNAQ 388
+ S + + A+N DP R T +A +HPFF + P +
Sbjct: 250 GVHLSSVMPYASADAVN-----LIERLCSWDPCNRPTTAEALQHPFFQSCYYIPPSLRPK 304
Query: 389 LTLPNEECHESDIKRYKSEMNESMSQRPPSAPT--GHTSTDNSIRAVTGAAFPKEAS--- 443
L+ P R E +S+ +R P+APT + + + T A F +
Sbjct: 305 LSEP----------RGSLEQQQSV-KRLPAAPTYNANKPLNTYVTPKTNAPFSNGVNSYV 353
Query: 444 IPK--APRPEHIKSTIPAQPSASRYNGAATQNIPKEPIP 480
PK AP + S + A+ +A NG PK P
Sbjct: 354 TPKTNAPFSNGVNSYVTAKTNAPFSNGVNNYVAPKMNAP 392
>7294866 [K] KOG0666 Cyclin C-dependent kinase CDK8
Length = 531
Score = 149 bits (376), Expect = 1e-35
Identities = 127/404 (31%), Positives = 184/404 (45%), Gaps = 85/404 (21%)
Query: 52 LNNYREEEKLGQGTFGEVFKGIHLGTN--RKVAIKRILVRAEKDLFPITAQREITILKRM 109
L NY E K+G+GT+G V+K T+ ++ A+K+I + ++A REI +L+ +
Sbjct: 96 LFNY-EGCKVGRGTYGHVYKAKWKETSDGKEYALKQI----DGTGLSMSACREIALLREL 150
Query: 110 NHKNIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDL 169
H+N++ LI + N +K+ F+++ Y DL
Sbjct: 151 KHQNVITLIRVFLSH-----------------------NDRKV------FLLIDYAEHDL 181
Query: 170 TGLLHNPR----------VEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILI--- 216
++ R V GM VK+++ Q+L+GI+Y+H N LHRD+K ANIL+
Sbjct: 182 WHIIKFHRAAKATKKQVVVPRGM--VKSLLYQILDGIHYLHSNWVLHRDLKPANILVMGD 239
Query: 217 -DHKGVVKIADFGLARNYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTT 275
+ +G VKIAD G AR + L A VVVT WYRAPE++LG RHYT
Sbjct: 240 GNERGRVKIADMGFARLFNAPLKPL---------ADLDPVVVTFWYRAPELLLGARHYTK 290
Query: 276 AVDIWGIGCVFAEFFEKKPILQ-GQTDI--------DQGHVIFKLMGTPSMDEWGLAYHL 326
A+DIW IGC+FAE +PI Q DI DQ IF +MG P +W +
Sbjct: 291 AIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPYHHDQLDRIFNVMGFPQDKDWEDIKKM 350
Query: 327 PGSE-LTKTNYKST--------LQERFSKALNETGXXXXXXXXXXDPYKRVTAMKAKKHP 377
P LTK +ST ER + DP KR+T+ +A +
Sbjct: 351 PEHHTLTKDFKRSTYSTCSLAKYMERHKIKPDSKAFHLLQKLLLMDPNKRITSEQAMQDQ 410
Query: 378 FFFEEPLP------NAQLTLPNEECHESDIKRYKSEMNESMSQR 415
+F EEP P + P E D + KS+ Q+
Sbjct: 411 YFQEEPQPTQDVFAGCPIPYPKREFLTDDDQEDKSDNKRQQQQQ 454
>At4g13020 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 443
Score = 149 bits (375), Expect = 2e-35
Identities = 112/381 (29%), Positives = 173/381 (45%), Gaps = 63/381 (16%)
Query: 55 YREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNHKNI 114
Y+ E+LG GT G V+K ++L T VA+K+ + R RE+ L+++NH +I
Sbjct: 12 YKILEELGDGTCGSVYKAVNLETYEVVAVKK-MKRKFYYWEECVNLREVKALRKLNHPHI 70
Query: 115 VKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGLLH 174
+KL EIV + + F I M +L ++
Sbjct: 71 IKLKEIVREHN-------------------------------ELFFIFECMDHNLYHIMK 99
Query: 175 NPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLARNYY 234
F ++++ M Q+L+G+ ++H N + HRD+K N+L+ + ++KIADFGLAR
Sbjct: 100 ERERPFSEGEIRSFMSQMLQGLAHMHKNGYFHRDLKPENLLVTNN-ILKIADFGLAREVA 158
Query: 235 GSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFEKKP 294
PP YT V TRWYRAPE++L YT AVD+W +G + AE + P
Sbjct: 159 SMPP-------------YTEYVSTRWYRAPEVLLQSSLYTPAVDMWAVGAILAELYALTP 205
Query: 295 ILQGQTDIDQGHVIFKLMGTPSMDEWGLAYHLPGSELTKTNYKSTLQERFSKALNETGXX 354
+ G+++IDQ + I ++G P + A + S + ++ Q R + L
Sbjct: 206 LFPGESEIDQLYKICCVLGKPDWTTFPEAKSI--SRIMSISHTEFPQTRIADLLPNAAPE 263
Query: 355 XXXXXX---XXDPYKRVTAMKAKKHPFF-----FEEPLPNAQL------TLPNEECHESD 400
DP KR TA +A HPFF P+ + +L LPN E + D
Sbjct: 264 AIDLINRLCSWDPLKRPTADEALNHPFFSMATQASYPIHDLELRLDNMAALPNLELNLWD 323
Query: 401 IKRYKSEMNESMSQR-PPSAP 420
R E ++ PSAP
Sbjct: 324 FNREPEECFLGLTLAVKPSAP 344
>Hs4507281 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 1030
Score = 148 bits (373), Expect = 3e-35
Identities = 122/487 (25%), Positives = 199/487 (40%), Gaps = 74/487 (15%)
Query: 44 KVYGVTKFLNNYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREI 103
K+ + +N + +G+G +G V K H T+ VAIK+ E + T RE+
Sbjct: 2 KIPNIGNVMNKFEILGVVGEGAYGVVLKCRHKETHEIVAIKKFKDSEENEEVKETTLREL 61
Query: 104 TILKRMNHKNIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILP 163
+L+ + +NIV+L E GK +++
Sbjct: 62 KMLRTLKQENIVELKEAFRRR------------------------------GK-LYLVFE 90
Query: 164 YMVSDLTGLLHNPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVK 223
Y+ ++ LL VK+ + QL++ I++ H N +HRDIK N+LI H V+K
Sbjct: 91 YVEKNMLELLEEMPNGVPPEKVKSYIYQLIKAIHWCHKNDIVHRDIKPENLLISHNDVLK 150
Query: 224 IADFGLARNYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIG 283
+ DFG ARN G+ A YT V TRWYR+PE++LG Y +VD+W +G
Sbjct: 151 LCDFGFARNL-----------SEGNNANYTEYVATRWYRSPELLLG-APYGKSVDMWSVG 198
Query: 284 CVFAEFFEKKPILQGQTDIDQGHVIFKLMGTPSMDEWGLAYHLP---GSELTKTNYKSTL 340
C+ E + +P+ G+++IDQ I K++G ++ L Y P G N+ +L
Sbjct: 199 CILGELSDGQPLFPGESEIDQLFTIQKVLGPLPSEQMKLFYSNPRFHGLRFPAVNHPQSL 258
Query: 341 QERFSKALNETGXXXXXXXXXXDPYKRVTAMKAKKHPFFFEEPLPNAQLTLPNEECHESD 400
+ R+ LN DP R + HP F Q L +
Sbjct: 259 ERRYLGILNSVLLDLMKNLLKLDPADRYLTEQCLNHPTF------QTQRLLDRSPSRSAK 312
Query: 401 IKRYKSE----MNESMSQRPPSAPTGHTSTDNSIRAVTGAAFPKEASIP----------- 445
K Y E N + + + + + H S I+ ++ + +P
Sbjct: 313 RKPYHVESSTLSNRNQAGKSTALQSHHRSNSKDIQNLSVGLPRADEGLPANESFLNGNLA 372
Query: 446 -KAPRPEHIKSTIPAQPSASRYNGAATQNIPKEPIPTAPLPKGPKNSIPTGPNKLPPNPR 504
+ P H K+ AS G+ ++++ IP PK K+ N + P P
Sbjct: 373 GASLSPLHTKTY-----QASSQPGSTSKDLTNNNIPHLLSPKEAKSKTEFDFN-IDPKPS 426
Query: 505 DSYASKY 511
+ +KY
Sbjct: 427 EGPGTKY 433
>7302908 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 317
Score = 146 bits (368), Expect = 1e-34
Identities = 95/335 (28%), Positives = 165/335 (48%), Gaps = 46/335 (13%)
Query: 54 NYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMN--- 110
NY+E +G+G +G V++ + T VA+K++ + ++ P++ REI++LK++N
Sbjct: 25 NYQELNIIGEGAYGTVYRARDVITGNIVALKKVRISLNENGVPMSTLREISLLKQLNASN 84
Query: 111 HKNIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLT 170
H NIVKL E+ + Q LI ++ ++ DL+
Sbjct: 85 HANIVKLYEVCQFLE---------------------RDGQLLI-----LLVFEHVEQDLS 118
Query: 171 GLLHN-PRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGL 229
L+ P+ ++ + +LL G++++H ++ +HRD+K N+L+ +G +KIADFGL
Sbjct: 119 DLIDRLPKSGMSPPTIQRLSRELLTGVDFLHSHRIIHRDLKPQNLLVSSQGHLKIADFGL 178
Query: 230 ARNYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEF 289
A+ Y GS K TSVVVT WYRAPE++L + Y + VDIW C+ E
Sbjct: 179 AKTY-------------GSEMKLTSVVVTLWYRAPEVLLA-QPYNSTVDIWSAACIIFEM 224
Query: 290 FEKKPILQGQTDIDQGHVIFKLMGTPSMDEWGLAYHLPGSELTKTNYKSTLQERFSKALN 349
F ++ + G ++ +Q IF+L G P+ +W + + + K + F L
Sbjct: 225 FNRRALFPGTSEKNQLDRIFELTGRPTEQQWPQTISVALEHFPQRHPKR--PKDFCPHLC 282
Query: 350 ETGXXXXXXXXXXDPYKRVTAMKAKKHPFFFEEPL 384
+ D + R +A+ +H +F +EPL
Sbjct: 283 KYADDLLNKMLSYDLHLRPSALACLEHDYFQQEPL 317
>Hs4502735 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 303
Score = 145 bits (367), Expect = 1e-34
Identities = 98/337 (29%), Positives = 159/337 (47%), Gaps = 49/337 (14%)
Query: 53 NNYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVR---AEKDLFPITAQREITILKRM 109
+ Y ++G G +G V+K + VA+K + V PI+ RE+ +L+R+
Sbjct: 4 SRYEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGGGGGGLPISTVREVALLRRL 63
Query: 110 N---HKNIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMV 166
H N+V+L+++ T +TD ++ +T ++ ++
Sbjct: 64 EAFEHPNVVRLMDVC----ATSRTD-----------------REIKVT-----LVFEHVD 97
Query: 167 SDLTGLLHN-PRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIA 225
DL L P +K++M Q L G++++H N +HRD+K NIL+ G VK+A
Sbjct: 98 QDLRTYLDKAPPPGLPAETIKDLMRQFLRGLDFLHANCIVHRDLKPENILVTSGGTVKLA 157
Query: 226 DFGLARNYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCV 285
DFGLAR Y T VVVT WYRAPE++L Y T VD+W +GC+
Sbjct: 158 DFGLARIY-------------SYQMALTPVVVTLWYRAPEVLLQST-YATPVDMWSVGCI 203
Query: 286 FAEFFEKKPILQGQTDIDQGHVIFKLMGTPSMDEWGLAYHLPGSELTKTNYKSTLQERFS 345
FAE F +KP+ G ++ DQ IF L+G P D+W LP + +
Sbjct: 204 FAEMFRRKPLFCGNSEADQLGKIFDLIGLPPEDDWPRDVSLPRGAFPPRGPRPV--QSVV 261
Query: 346 KALNETGXXXXXXXXXXDPYKRVTAMKAKKHPFFFEE 382
+ E+G +P+KR++A +A +H + ++
Sbjct: 262 PEMEESGAQLLLEMLTFNPHKRISAFRALQHSYLHKD 298
>YBL016w [T] KOG0660 Mitogen-activated protein kinase
Length = 353
Score = 144 bits (363), Expect = 4e-34
Identities = 106/345 (30%), Positives = 160/345 (45%), Gaps = 37/345 (10%)
Query: 45 VYGVTKFLNNYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREIT 104
VY ++ ++++ + LG+G +G V H T VAIK+I +K LF + REI
Sbjct: 6 VYNIS---SDFQLKSLLGEGAYGVVCSATHKPTGEIVAIKKI-EPFDKPLFALRTLREIK 61
Query: 105 ILKRMNHKNIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPY 164
ILK H+NI+ + I RP + N Q+L+ +I
Sbjct: 62 ILKHFKHENIITIFNI--------------QRPDSFENFNEVYIIQELMQTDLHRVISTQ 107
Query: 165 MVSDLTGLLHNPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKI 224
M+SD ++ + Q L + +H + +HRD+K +N+LI+ +K+
Sbjct: 108 MLSD--------------DHIQYFIYQTLRAVKVLHGSNVIHRDLKPSNLLINSNCDLKV 153
Query: 225 ADFGLARNYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGC 284
DFGLAR S + P G SG T V TRWYRAPE++L Y+ A+D+W GC
Sbjct: 154 CDFGLARIIDESAADNSEPTGQQSGM--TEYVATRWYRAPEVMLTSAKYSRAMDVWSCGC 211
Query: 285 VFAEFFEKKPILQGQTDIDQGHVIFKLMGTPSMDEWGLAYHLP-GSELTKT--NYKSTLQ 341
+ AE F ++PI G+ Q +IF ++GTP D P E K+ Y +
Sbjct: 212 ILAELFLRRPIFPGRDYRHQLLLIFGIIGTPHSDNDLRCIESPRAREYIKSLPMYPAAPL 271
Query: 342 ERFSKALNETGXXXXXXXXXXDPYKRVTAMKAKKHPFFFEEPLPN 386
E+ +N G DP KR+TA +A +HP+ PN
Sbjct: 272 EKMFPRVNPKGIDLLQRMLVFDPAKRITAKEALEHPYLQTYHDPN 316
>Hs20551615 [K] KOG0666 Cyclin C-dependent kinase CDK8
Length = 358
Score = 144 bits (363), Expect = 4e-34
Identities = 107/362 (29%), Positives = 166/362 (45%), Gaps = 74/362 (20%)
Query: 60 KLGQGTFGEVFKGIHLG--TNRKVAIKRILVRAEKDLFPITAQREITILKRMNHKNIVKL 117
K+G+GT+G V+K ++ A+K+I E ++A REI +L+ + H N++ L
Sbjct: 26 KVGRGTYGHVYKARRKDGKDEKEYALKQI----EGTGISMSACREIALLRELKHPNVIAL 81
Query: 118 IEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGLLHNPR 177
++ S + +++ Y DL ++ R
Sbjct: 82 QKVFLSHSD-----------------------------RKVWLLFDYAEHDLWHIIKFHR 112
Query: 178 --------VEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILI----DHKGVVKIA 225
++ + VK+++ Q+L+GI+Y+H N LHRD+K ANIL+ +G VKIA
Sbjct: 113 ASKANKKPMQLPRSMVKSLLYQILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIA 172
Query: 226 DFGLARNYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCV 285
D G AR + L A VVVT WYRAPE++LG RHYT A+DIW IGC+
Sbjct: 173 DMGFARLFNSPLKPL---------ADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCI 223
Query: 286 FAEFFEKKPILQ-GQTDI--------DQGHVIFKLMGTPSMDEWGLAYHLPGSELTKTNY 336
FAE +PI Q DI DQ IF +MG P+ +W +P + ++
Sbjct: 224 FAELLTSEPIFHCRQEDIKTSNPFHHDQLDRIFSVMGFPADKDWEDIRKMPEYPTLQKDF 283
Query: 337 KST---------LQERFSKALNETGXXXXXXXXXXDPYKRVTAMKAKKHPFFFEEPLPNA 387
+ T E+ + DP KR+T+ +A + P+F E+PLP
Sbjct: 284 RRTTYANSSLIKYMEKHKVKPDSKVFLLLQKLLTMDPTKRITSEQALQDPYFQEDPLPTL 343
Query: 388 QL 389
+
Sbjct: 344 DI 345
>Hs4505569 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 493
Score = 144 bits (362), Expect = 5e-34
Identities = 97/331 (29%), Positives = 146/331 (43%), Gaps = 47/331 (14%)
Query: 52 LNNYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNH 111
+ Y +G+G++G V K + T R VAIK+ L + + A REI +LK++ H
Sbjct: 1 MEKYENLGLVGEGSYGMVMKCRNKDTGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRH 60
Query: 112 KNIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTG 171
+N+V L+E+ + K ++++ ++ +
Sbjct: 61 ENLVNLLEVCKKK-------------------------------KRWYLVFEFVDHTILD 89
Query: 172 LLHNPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLAR 231
L V+ + Q++ GI + H + +HRDIK NIL+ GVVK+ DFG AR
Sbjct: 90 DLELFPNGLDYQVVQKYLFQIINGIGFCHSHNIIHRDIKPENILVSQSGVVKLCDFGFAR 149
Query: 232 NYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFE 291
A G YT V TRWYRAPE+++GD Y AVD+W IGC+ E F
Sbjct: 150 TL------------AAPGEVYTDYVATRWYRAPELLVGDVKYGKAVDVWAIGCLVTEMFM 197
Query: 292 KKPILQGQTDIDQGHVIFKLMGTPSMDEWGLAYHLP---GSELTKTNYKSTLQERFSKAL 348
+P+ G +DIDQ + I +G L P G L + + L+ R+ K L
Sbjct: 198 GEPLFPGDSDIDQLYHIMMCLGNLIPRHQELFNKNPVFAGVRLPEIKEREPLERRYPK-L 256
Query: 349 NETGXXXXXXXXXXDPYKRVTAMKAKKHPFF 379
+E DP KR + H FF
Sbjct: 257 SEVVIDLAKKCLHIDPDKRPFCAELLHHDFF 287
>7291043 [T] KOG0660 Mitogen-activated protein kinase
Length = 392
Score = 143 bits (361), Expect = 7e-34
Identities = 105/405 (25%), Positives = 180/405 (43%), Gaps = 55/405 (13%)
Query: 59 EKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMN-HKNIVKL 117
+++G+G +G V+K T VA+K++ + RE+ L+ H NIV+L
Sbjct: 29 KRMGKGAYGIVWKATDRRTKNTVALKKVFDAFRDETDAQRTYREVIFLRAFRCHPNIVRL 88
Query: 118 IEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGLLHNPR 177
++I K F+++ +M SDL ++
Sbjct: 89 VDIF-----------------------------KASNNLDFYLVFEFMESDLHNVIKRGN 119
Query: 178 VEFGMADVKN--IMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLARNYYG 235
V + DV +M QL+ I +IH +HRD+K +NILID K +K+ADFGLAR
Sbjct: 120 V---LKDVHKRFVMYQLINAIKFIHSGNVIHRDLKPSNILIDSKCRLKVADFGLARTL-- 174
Query: 236 SPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFEKKPI 295
+ + T V TRWYRAPEI++ R+YT +D+WG+GC+ E +KP+
Sbjct: 175 --SSRRIYDDLEQDGMLTDYVATRWYRAPEILVASRNYTKGIDMWGLGCILGEMIRQKPL 232
Query: 296 LQGQTDIDQGHVIFKLMGTPSMDEWGLAYHLP--GSELTKTNYKSTLQ---ERFSKALNE 350
QG + ++Q I + P++ + +A P GS L N + + + K +
Sbjct: 233 FQGTSTVNQIEKI--VTSLPNVTKLDIASIGPSFGSVLLSRNIQRDRRYSLDEMMKNCCD 290
Query: 351 TGXXXXXXXXXXDPYKRVTAMKAKKHPFFFEEPLPNAQLTL------PNEECHESDIKRY 404
G +P+ R+TA +A +HP+ +A++ L P ++ D+ +Y
Sbjct: 291 DGISLVKALLVLNPHNRLTAKEAIRHPYVSRFQYASAEMDLHMDVVPPLKDHVRYDVDQY 350
Query: 405 KSEMNESMSQRPPSAPTGHTSTDNSIRAVTGAAFPKEASIPKAPR 449
++ + E + + + + NS + PK + K R
Sbjct: 351 RNSLYELIDR---ETSCSNRTVSNSTPSSNRDELPKPVRVTKQAR 392
>ECU11g0960 [D] KOG0600 Cdc2-related protein kinase
Length = 329
Score = 143 bits (360), Expect = 9e-34
Identities = 100/349 (28%), Positives = 160/349 (45%), Gaps = 52/349 (14%)
Query: 37 VQSRENEKVYGVTKFLNNYREEEKL---GQGTFGEVFKGIHLGTNRKVAIKRILVRAEKD 93
++ E ++ +F E EK+ G+GTFG+V + + A+K+ V EK+
Sbjct: 1 MEPAEEGEILAHRRFTATKMEYEKIRIIGEGTFGQVI--LARKGRARYALKK--VSKEKE 56
Query: 94 LFPITAQREITILKRMNHKNIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLI 153
+T RE+ +L+ M H +IV+LIE+V +
Sbjct: 57 GLSVTTIREVQVLRAMGHPSIVRLIEVVVEP----------------------------- 87
Query: 154 TGKHFFMILPYMVSDLTGLLHNPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTAN 213
G +M+ PY DL + + ++ +++K+I Q+ +G+ YIH +HRD+K+AN
Sbjct: 88 -GGDIYMVFPYFPYDLNRFIRSNKMT--CSEIKHIFYQIAQGVCYIHSKGIMHRDLKSAN 144
Query: 214 ILIDHKGVVKIADFGLARNYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHY 273
IL+D K IADFG+AR Y G+ YT +VT WYRAPEI+LG Y
Sbjct: 145 ILLDQKLNASIADFGMAR----------YTTKTGA---YTPGMVTLWYRAPEILLGSSSY 191
Query: 274 TTAVDIWGIGCVFAEFFEKKPILQGQTDIDQGHVIFKLMGTPSMDEWGLAYHLPGSELTK 333
T AVDIW +GC+ E + I QG T++ Q ++ G+ + + + LPG +
Sbjct: 192 TYAVDIWSLGCILTEMYLGHMIFQGSTEMLQLEMVIHACGSINENSYPGVQDLPGFRNFR 251
Query: 334 TNYKSTLQERFSKALNETGXXXXXXXXXXDPYKRVTAMKAKKHPFFFEE 382
E + + + DP KR+T + +F E
Sbjct: 252 LPQSPRRIEGIIRKHDASAVELVSKMLCLDPSKRITVEQVVGSKYFEHE 300
>7300773 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 302
Score = 142 bits (359), Expect = 1e-33
Identities = 89/275 (32%), Positives = 133/275 (48%), Gaps = 41/275 (14%)
Query: 53 NNYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNHK 112
+ Y+ EK+G+G G VFK I L N++VAIK++ ++ + + REI L+ +
Sbjct: 7 SRYKMLEKIGEGVHGCVFKAIDLQRNKEVAIKKVALKNKFGNIALNTLREIKTLQLCKSE 66
Query: 113 NIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGL 172
I+ +I+I D +TG ++L Y L
Sbjct: 67 YILDIIDIYPD-----------------------------LTG--LSLVLEYQPDTLYNR 95
Query: 173 LHNPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLARN 232
L + V+ Q+ +GI Y+H +HRDIK AN+LI ++KIADFGLAR
Sbjct: 96 LKSEVNPLSRQQVRKFAHQMFKGIAYLHEAGLMHRDIKPANLLISDTDMLKIADFGLARL 155
Query: 233 YYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFEK 292
Y+ + Y+ V TRWYRAPEI+ G + Y T VD+W GCV AE
Sbjct: 156 YFPEDES----------RLYSPQVSTRWYRAPEILFGSQKYGTGVDMWAAGCVVAEMLRG 205
Query: 293 KPILQGQTDIDQGHVIFKLMGTPSMDEWGLAYHLP 327
P+ G TDI+Q +I + +G+P +++W LP
Sbjct: 206 VPLFAGTTDIEQLAIIIRTLGSPRLNQWPELTSLP 240
>7298087 [T] KOG0660 Mitogen-activated protein kinase
Length = 365
Score = 141 bits (356), Expect = 3e-33
Identities = 94/356 (26%), Positives = 163/356 (45%), Gaps = 53/356 (14%)
Query: 55 YREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNHKNI 114
Y+ + +GQG +G+V K + GT+ KVAIK++ + + RE+ +LK M+H+N+
Sbjct: 24 YQNLQPVGQGAYGQVCKAVVRGTSTKVAIKKLARPFQSAVHAKRTYRELRLLKHMDHENV 83
Query: 115 VKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGLLH 174
+ L+++ + P D + +M+ M +DL ++
Sbjct: 84 IGLLDVFHPGQPADSLDQF----------------------QQVYMVTHLMDADLNNIIR 121
Query: 175 NPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLARNYY 234
++ V+ ++ Q+L G+ YIH +HRD+K +NI ++ ++I DFGLAR
Sbjct: 122 TQKLSDD--HVQFLVYQILRGLKYIHSAGVIHRDLKPSNIAVNEDCELRILDFGLARP-- 177
Query: 235 GSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFEKKP 294
+ ++ T V TRWYRAPEI+L HY DIW +GC+ AE +
Sbjct: 178 -------------AESEMTGYVATRWYRAPEIMLNWMHYNQTADIWSVGCIMAELLTGRT 224
Query: 295 ILQGQTDIDQGHVIFKLMGTPSMDEWGLAYHLPGSELTKTNYKSTLQ-------ERFSKA 347
+ G I Q ++I +++GTP+ DE+ S + NY +L +
Sbjct: 225 LFPGTDHIHQLNLIMEVLGTPA-DEFMSRI----SSESARNYIRSLPVMPRRNFRDIFRG 279
Query: 348 LNETGXXXXXXXXXXDPYKRVTAMKAKKHPFF--FEEPLPNAQLTLPNEECHESDI 401
N D KR+TA +A HP+ + +P L ++ E+++
Sbjct: 280 ANPLAIDLLEKMLELDADKRITAEQALAHPYMEKYHDPTDEQTAALYDQSFEENEL 335
>Hs7706059 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 455
Score = 141 bits (355), Expect = 4e-33
Identities = 128/466 (27%), Positives = 190/466 (40%), Gaps = 78/466 (16%)
Query: 55 YREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNHKNI 114
Y K+G+G++G V K H T + VAIK R E+ + I A REI LK+ +H+N+
Sbjct: 4 YETLGKVGEGSYGTVMKCKHKNTGQIVAIKIFYERPEQSVNKI-AMREIKFLKQFHHENL 62
Query: 115 VKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGLLH 174
V LIE+ +QK F I ++ +L H
Sbjct: 63 VNLIEVF---------------------------RQKKKIHLVFEFIDHTVLDELQHYCH 95
Query: 175 NPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLARNYY 234
+ ++ + Q+L I+Y+H N +HRDIK NIL+ G+ K+ DFG AR
Sbjct: 96 GLESK----RLRKYLFQILRAIDYLHSNNIIHRDIKPENILVSQSGITKLCDFGFARTL- 150
Query: 235 GSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFEKKP 294
A G YT V TRWYRAPE+VL D Y VDIW +GC+ E P
Sbjct: 151 -----------AAPGDIYTDYVATRWYRAPELVLKDTSYGKPVDIWALGCMIIEMATGNP 199
Query: 295 ILQGQTDIDQGHVIFKLMGTPSMDEWGLAYHLP---GSELTKTNYKSTLQERFSKALNET 351
L +D+D H I +G S + P G L + + ++++ K LN
Sbjct: 200 YLPSSSDLDLLHKIVLKVGNLSPHLQNIFSKSPIFAGVVLPQVQHPKNARKKYPK-LNGL 258
Query: 352 GXXXXXXXXXXDPYKRVTAMKAKKHPF-----FFEEPLPNAQLTLPNEECHESDIKRYKS 406
DP R+++ H + F E+ +P + L E S IK +S
Sbjct: 259 LADIVHACLQIDPADRISSSDLLHHEYFTRDGFIEKFMPELKAKLLQEAKVNSLIKPKES 318
Query: 407 EMNESMSQRPPSAPTGHTSTDNSIRAVTGAAFPKEASIPKAPRPEHIKSTI--------- 457
+ R T +T+T ++ + +E I K +P+ IK +
Sbjct: 319 SKENEL--RKDERKTVYTNT-----LLSSSVLGEE--IEKEKKPKEIKVRVIKVKGGRGD 369
Query: 458 PAQPSASRYNGAATQNIPKEPIPTAPLPKGPKNSIPTGPNKLPPNP 503
++P Y G Q E + P P + T PPNP
Sbjct: 370 ISEPKKKEYEGGLGQQDANENVH----PMSPDTKLVTIE---PPNP 408
>Hs4758652 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 358
Score = 140 bits (354), Expect = 5e-33
Identities = 95/333 (28%), Positives = 152/333 (45%), Gaps = 51/333 (15%)
Query: 52 LNNYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNH 111
+ Y + K+G+G++G VFK + T + VAIK+ L + + A REI +LK++ H
Sbjct: 2 MEKYEKIGKIGEGSYGVVFKCRNRDTGQIVAIKKFLESEDDPVIKKIALREIRMLKQLKH 61
Query: 112 KNIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTG 171
N+V L+E+ + + ++ Y D T
Sbjct: 62 PNLVNLLEVFRRK-------------------------------RRLHLVFEYC--DHTV 88
Query: 172 LLHNPRVEFGMAD--VKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGL 229
L R + G+ + VK+I Q L+ +N+ H + +HRD+K NILI V+K+ DFG
Sbjct: 89 LHELDRYQRGVPEHLVKSITWQTLQAVNFCHKHNCIHRDVKPENILITKHSVIKLCDFGF 148
Query: 230 ARNYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEF 289
AR G YT V TRWYR+PE+++GD Y VD+W IGCVFAE
Sbjct: 149 ARLL------------TGPSDYYTDYVATRWYRSPELLVGDTQYGPPVDVWAIGCVFAEL 196
Query: 290 FEKKPILQGQTDIDQGHVIFKLMG---TPSMDEWGLAYHLPGSELTKTNYKSTLQERFSK 346
P+ G++D+DQ ++I K +G + + G ++ L+ +F
Sbjct: 197 LSGVPLWPGKSDVDQLYLIRKTLGDLIPRHQQVFSTNQYFSGVKIPDPEDMEPLELKFPN 256
Query: 347 ALNETGXXXXXXXXXXDPYKRVTAMKAKKHPFF 379
++ DP +R+T + HP+F
Sbjct: 257 -ISYPALGLLKGCLHMDPTERLTCEQLLHHPYF 288
>At4g19110 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 256
Score = 140 bits (354), Expect = 5e-33
Identities = 89/285 (31%), Positives = 133/285 (46%), Gaps = 56/285 (19%)
Query: 101 REITILKRMNHKNIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFM 160
RE+ L+RMNH NIVKL E++ + +
Sbjct: 15 REVKSLRRMNHPNIVKLKEVIRENDI-------------------------------LYF 43
Query: 161 ILPYMVSDLTGLLHNPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKG 220
+ YM +L L+ + + F AD+KN Q+ +G++Y+H + HRD+K N+L+ K
Sbjct: 44 VFEYMECNLYQLMKDRQKLFAEADIKNWCFQVFQGLSYMHQRGYFHRDLKPENLLVS-KD 102
Query: 221 VVKIADFGLARNYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIW 280
++KIADFGLAR SPP +T V TRWYRAPE++L YT+ VD+W
Sbjct: 103 IIKIADFGLAREVNSSPP-------------FTEYVSTRWYRAPEVLLQSYVYTSKVDMW 149
Query: 281 GIGCVFAEFFEKKPILQGQTDIDQGHVIFKLMGTPSMDEWGLAYHLPGSELTKT-NYK-- 337
+G + AE +PI G ++ D+ + I ++GTP+ + W L G L T NY+
Sbjct: 150 AMGAIMAELLSLRPIFPGASEADEIYKICSVIGTPTEETW-----LEGLNLANTINYQFP 204
Query: 338 ---STLQERFSKALNETGXXXXXXXXXXDPYKRVTAMKAKKHPFF 379
+ +E DP R TA + +HPFF
Sbjct: 205 QLPGVPLSSLMPSASEDAINLIERLCSWDPSSRPTAAEVLQHPFF 249
>ECU08g0230 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 265
Score = 140 bits (353), Expect = 6e-33
Identities = 89/257 (34%), Positives = 139/257 (53%), Gaps = 54/257 (21%)
Query: 61 LGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNHKNIVKLIEI 120
+G GT+GEV++ I T KVA+KRI + EK+ P TA REI+ILK+++H+NI+ L+ I
Sbjct: 10 IGSGTYGEVYEAIDTETKEKVALKRIRLN-EKEGMPGTALREISILKKLSHRNIISLVSI 68
Query: 121 VYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGLLHNPRVEF 180
++ ++ L+T M+ P++ +L +
Sbjct: 69 IHTDA--------------------------LLT-----MVFPFIDYELKKYI------- 90
Query: 181 GMADVKNIML---QLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLARNYYGSP 237
GM KNIM QL+ G++Y+H +HRD+K NIL+ GV+KIADFGL+R+
Sbjct: 91 GMNTGKNIMELVNQLICGVHYLHRMNVVHRDLKPQNILVTSDGVLKIADFGLSRSL---- 146
Query: 238 PNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFEKKPILQ 297
++ P Y+S VVT WYR+PE+++G Y VDIW +GC+ E +P+
Sbjct: 147 -EIRVP-------PYSSEVVTLWYRSPELLMGSTSYRFYVDIWSLGCIIYEMITLEPLFP 198
Query: 298 GQTDIDQGHVIFKLMGT 314
G++ +Q +I + GT
Sbjct: 199 GESKENQLTLIRRKAGT 215
>7301110 [T] KOG0660 Mitogen-activated protein kinase
Length = 366
Score = 140 bits (353), Expect = 6e-33
Identities = 93/345 (26%), Positives = 158/345 (44%), Gaps = 51/345 (14%)
Query: 55 YREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNHKNI 114
Y++ + +G G +G+V K + GTN VAIK++ + + RE+ +LK M+H+N+
Sbjct: 25 YQDLQPVGSGAYGQVSKAVVRGTNMHVAIKKLARPFQSAVHAKRTYRELRLLKHMDHENV 84
Query: 115 VKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGLLH 174
+ L++I + P P L + +++ M +DL ++
Sbjct: 85 IGLLDIFH------------PHPANG----------SLENFQQVYLVTHLMDADLNNIIR 122
Query: 175 NPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLARNYY 234
+ V+ ++ Q+L G+ YIH +HRD+K +NI ++ ++I DFGLAR
Sbjct: 123 MQHLSDD--HVQFLVYQILRGLKYIHSAGVIHRDLKPSNIAVNEDCELRILDFGLARP-- 178
Query: 235 GSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFEKKP 294
+ + T V TRWYRAPEI+L HY VDIW +GC+ AE ++
Sbjct: 179 -------------TENEMTGYVATRWYRAPEIMLNWMHYDQTVDIWSVGCIMAELITRRT 225
Query: 295 ILQGQTDIDQGHVIFKLMGTPSMD-------EWGLAYHLPGSELTKTNYKSTLQERFSKA 347
+ G I Q ++I +++GTP + E +Y + ++K+ K
Sbjct: 226 LFPGTDHIHQLNLIMEMLGTPPAEFLKKISSESARSYIQSLPPMKGRSFKNVF-----KN 280
Query: 348 LNETGXXXXXXXXXXDPYKRVTAMKAKKHPFFFEEPLPNAQLTLP 392
N D KR+TA +A HP+ + P+ + T P
Sbjct: 281 ANPLAIDLLEKMLELDAEKRITAEEALSHPYLEKYAEPSVEQTSP 325
>SPBC8D2.01 [G] KOG0658 Glycogen synthase kinase-3
Length = 381
Score = 139 bits (350), Expect = 1e-32
Identities = 98/346 (28%), Positives = 150/346 (43%), Gaps = 48/346 (13%)
Query: 54 NYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNHKN 113
+Y LG G+FG V + +GT +A+KR+L RE+ I++ ++H N
Sbjct: 24 SYEPCRVLGSGSFGVVIQAKLVGTPGFIAVKRVLQDKRYK------NRELQIMRAISHPN 77
Query: 114 IVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYM---VSDLT 170
I+KLI + +P+ D T H ++L YM V D
Sbjct: 78 IIKLIAFFHTHNPSK--DET-----------------------HLCLLLEYMPETVFDDM 112
Query: 171 GLLHNPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHK-GVVKIADFGL 229
R +K QL + Y+H HRDIK N+L+D+K G++K+ DFG
Sbjct: 113 RWYTRRRKSIPNLSIKLYAFQLFRALAYLHSTGVCHRDIKPQNLLVDYKTGILKLCDFGS 172
Query: 230 ARNYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEF 289
A+ S PN+ Y + +R+YRAPE+V G HYTT +D+W CV AE
Sbjct: 173 AKVLVPSEPNVSY-------------ICSRYYRAPELVFGATHYTTKIDVWSAACVIAEL 219
Query: 290 FEKKPILQGQTDIDQGHVIFKLMGTPSMDEWGLAYHLPGSELTKTNYKSTLQERFSKALN 349
F +P+ G + ++Q I +++GTPS E + + TL+
Sbjct: 220 FIGRPLFPGDSSVEQLVEIIRVLGTPSYHEISVMNPNYVNHSLPNVRPHTLESVMPHNCT 279
Query: 350 ETGXXXXXXXXXXDPYKRVTAMKAKKHPFFFEEPLPNAQLTLPNEE 395
+ P KR++A++ HPFF E PN +E
Sbjct: 280 KNAMDLLHKMLTYVPSKRISAIEVLTHPFFDELRDPNCMYHCSRDE 325
>ECU08g1790 [D] KOG0600 Cdc2-related protein kinase
Length = 309
Score = 137 bits (345), Expect = 5e-32
Identities = 102/355 (28%), Positives = 162/355 (44%), Gaps = 52/355 (14%)
Query: 52 LNNYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNH 111
+ Y +++G+G FG+V+K AIK++ V E FP TA REI + K + +
Sbjct: 1 MEKYENIKQVGEGAFGQVYKSRRTSDGAVFAIKKMPVDRETG-FPFTAIREIKLCKSVIN 59
Query: 112 KNIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTG 171
K+I+ L EIV++E F++L YM DLTG
Sbjct: 60 KHIIGLDEIVFEEG-------------------------------FIFVVLEYMPYDLTG 88
Query: 172 LLHNPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLAR 231
LL + + +++I QL+E ++ +H +HRDIK +NIL+D G++K+ DFGL R
Sbjct: 89 LLASG-AKLSTDQIRSITSQLIEAVSSMHGMGLVHRDIKPSNILLDCHGMLKLTDFGLTR 147
Query: 232 NYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFE 291
G T+ V T WYRAPE++LG+ Y+ VD W +GC+ E
Sbjct: 148 EISGM---------------MTNRVCTLWYRAPELLLGETSYSLKVDAWSVGCIMLEMRL 192
Query: 292 KKPILQGQTDIDQGHVIFKLMGTPSMDEWGLAYHLPGSELTKT-NYKSTLQERFSKALNE 350
+P +G ++ Q +IF+ +G P D++ + L +K+ + + + ER+ +E
Sbjct: 193 GRPPYRGSDEVSQIKLIFEELGIP-QDKYKWSDLLDVDIYSKSRSTEEIIAERYGHLFDE 251
Query: 351 TGXXXXXXXXXXDPYKRVTAMKAKKHPFFFEEPLPNAQLTLPNEECHESDIKRYK 405
KR++ A F N + L EE HE K K
Sbjct: 252 EELKVLSGFLCLTSRKRLSV--ANSRYFTVISSHKNTYIPLSFEEAHELYTKERK 304
>CE11556 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 305
Score = 137 bits (345), Expect = 5e-32
Identities = 88/266 (33%), Positives = 130/266 (48%), Gaps = 62/266 (23%)
Query: 55 YREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNHKNI 114
Y + G+G FG V T+++VAIKRI+V ++ ++ REI+ L+ ++H+NI
Sbjct: 8 YETIQVAGRGAFGLVVIARDTLTSKRVAIKRIMV---PNVSKVSLAREISCLRNLHHRNI 64
Query: 115 VKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGLLH 174
+KL++ P D S ++T + +PY
Sbjct: 65 LKLLDCF------PSADLMS-----------------IVTEE-----VPYTW-------- 88
Query: 175 NPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLARNYY 234
Q+L GI Y+H + +HRDIK NIL+ + VVKIADFG A Y
Sbjct: 89 -------------YYTQILSGIAYLHSKEIMHRDIKPENILVTSRNVVKIADFGQACFYM 135
Query: 235 GSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFEKKP 294
PN +Y V TRWYRAPE++ G + Y VDIW IGC+ AE KP
Sbjct: 136 PKDPNQEYDVN----------VATRWYRAPELLFGSKKYKPDVDIWAIGCILAELVRGKP 185
Query: 295 ILQGQTDIDQGHVIFKLMGTPSMDEW 320
I G+++++Q +IF ++GTP+ D W
Sbjct: 186 IFPGRSELEQISIIFGVLGTPNEDNW 211
>YPL042c [K] KOG0666 Cyclin C-dependent kinase CDK8
Length = 555
Score = 136 bits (343), Expect = 9e-32
Identities = 95/307 (30%), Positives = 144/307 (45%), Gaps = 59/307 (19%)
Query: 98 TAQREITILKRMNHKNIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKH 157
+A RE+ + + +++K++ L+EI + K
Sbjct: 203 SACREMALCRELHNKHLTTLVEIFLER-------------------------------KC 231
Query: 158 FFMILPYMVSDLTGLLH-NPRVEFGMAD---VKNIMLQLLEGINYIHCNKFLHRDIKTAN 213
M+ Y DL ++H + E M V++IM QLL+G++Y+H N LHRD+K AN
Sbjct: 232 VHMVYEYAEHDLLQIIHFHSHPEKRMIPPRMVRSIMWQLLDGVSYLHQNWVLHRDLKPAN 291
Query: 214 ILIDHKGVVKIADFGLARNYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHY 273
I++ G VKI D GLAR ++ L Y G VVVT WYRAPE++LG RHY
Sbjct: 292 IMVTIDGCVKIGDLGLARKFHNMLQTL-YTGD--------KVVVTIWYRAPELLLGARHY 342
Query: 274 TTAVDIWGIGCVFAEFFEKKPILQGQT-----------DIDQGHVIFKLMGTPSMDEWGL 322
T AVD+W +GC+FAE +PI +G+ ++Q I +++GTP W
Sbjct: 343 TPAVDLWSVGCIFAELIGLQPIFKGEEAKLDSKKTVPFQVNQLQRILEVLGTPDQKIWPY 402
Query: 323 AYHLPG-SELTK-TNYKSTLQERFSKA--LNETGXXXXXXXXXXDPYKRVTAMKAKKHPF 378
P ++TK Y+ L + A ++ DP KR+ A A +H +
Sbjct: 403 LEKYPEYDQITKFPKYRDNLATWYHSAGGRDKHALSLLYHLLNYDPIKRIDAFNALEHKY 462
Query: 379 FFEEPLP 385
F E +P
Sbjct: 463 FTESDIP 469
>At3g59790 [T] KOG0660 Mitogen-activated protein kinase
Length = 393
Score = 136 bits (343), Expect = 9e-32
Identities = 91/320 (28%), Positives = 148/320 (45%), Gaps = 43/320 (13%)
Query: 61 LGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNHKNIVKLIEI 120
+G+G G V + TN KVAIK+I + + REI +L+ +H+NIV + ++
Sbjct: 66 IGRGACGIVCSAVDSETNEKVAIKKITQVFDNTIEAKRTLREIKLLRHFDHENIVAIRDV 125
Query: 121 VYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGLLHNPRVEF 180
+ P+ DS + +++ M DL L + + E
Sbjct: 126 IL----PPQRDSF----------------------EDVYIVNELMEFDLYRTLKSDQ-EL 158
Query: 181 GMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLARNYYGSPPNL 240
M Q+L G+ YIH LHRD+K +N+L+ + +KI DFGLAR
Sbjct: 159 TKDHGMYFMYQILRGLKYIHSANVLHRDLKPSNLLLSTQCDLKICDFGLAR--------- 209
Query: 241 KYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFEKKPILQGQT 300
T VVTRWYRAPE++LG YT A+D+W +GC+F E ++P+ G+
Sbjct: 210 ----ATPESNLMTEYVVTRWYRAPELLLGSSDYTAAIDVWSVGCIFMEIMNREPLFPGKD 265
Query: 301 DIDQGHVIFKLMGTPSMDEWGLAYHLPGSELTK--TNYKSTLQERFSKALNETGXXXXXX 358
++Q ++ +L+GTPS +E G + + T + + E+F +
Sbjct: 266 QVNQLRLLLELIGTPSEEELGSLSEYAKRYIRQLPTLPRQSFTEKFPN-VPPLAIDLVEK 324
Query: 359 XXXXDPYKRVTAMKAKKHPF 378
DP +R++ +A HP+
Sbjct: 325 MLTFDPKQRISVKEALAHPY 344
>SPAC1687.15 [G] KOG0658 Glycogen synthase kinase-3
Length = 387
Score = 135 bits (341), Expect = 1e-31
Identities = 97/337 (28%), Positives = 146/337 (42%), Gaps = 42/337 (12%)
Query: 54 NYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNHKN 113
+Y + +G G+FG V + + ++ K AIKR+L RE+ I++ M H N
Sbjct: 31 SYTSSKVVGSGSFGVVMQVHLIESDSKAAIKRVLQDKR------FKNRELQIMRIMKHPN 84
Query: 114 IVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGLL 173
IV LI Y T + + +P + + L
Sbjct: 85 IVDLIAYYY----------------------TTGDNSDEVYLNLVLEFMPETIYRASRLY 122
Query: 174 HNPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILID-HKGVVKIADFGLARN 232
++ M +VK + QLL + YIH + HRDIK N+L+D G++K+ DFG A+
Sbjct: 123 TRQKLSMPMLEVKLYIYQLLRSLAYIHASGICHRDIKPQNLLLDPENGILKLCDFGSAKI 182
Query: 233 YYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFEK 292
PN+ Y + +R+YRAPE++ G YT A+DIW GCV AE
Sbjct: 183 LVAGEPNVSY-------------ICSRYYRAPELIFGATDYTHAIDIWSTGCVMAELMLG 229
Query: 293 KPILQGQTDIDQGHVIFKLMGTPSMDEWGLAYHLPGSELTKTNYKSTLQERFSKALNETG 352
P+ G++ IDQ I K++GTPS ++ L FS+++
Sbjct: 230 HPLFPGESGIDQLVEIIKILGTPSREQIKTMNPNYMEHRFPQIRPQPLSRVFSRSVPLDA 289
Query: 353 XXXXXXXXXXDPYKRVTAMKAKKHPFFFEEPLPNAQL 389
P R+TA +A HPFF E PN +L
Sbjct: 290 LDLLSKMLQYTPTDRLTAAEAMCHPFFDELRDPNTKL 326
>At2g43790 [T] KOG0660 Mitogen-activated protein kinase
Length = 395
Score = 135 bits (341), Expect = 1e-31
Identities = 88/320 (27%), Positives = 152/320 (47%), Gaps = 43/320 (13%)
Query: 61 LGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNHKNIVKLIEI 120
+G+G +G V ++ TN VAIK+I + + REI +L+ M+H+NIV + +I
Sbjct: 69 IGKGAYGIVCSAMNSETNESVAIKKIANAFDNKIDAKRTLREIKLLRHMDHENIVAIRDI 128
Query: 121 VYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGLLHNPRVEF 180
+ P P+ N + ++ M +DL ++ + +
Sbjct: 129 I-------------PPPLRNAFND-------------VYIAYELMDTDLHQIIRSNQA-L 161
Query: 181 GMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLARNYYGSPPNL 240
+ + Q+L G+ YIH LHRD+K +N+L++ +KI DFGLAR S
Sbjct: 162 SEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARVTSESDFMT 221
Query: 241 KYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFEKKPILQGQT 300
+Y VVTRWYRAPE++L YT A+D+W +GC+F E ++KP+ G+
Sbjct: 222 EY-------------VVTRWYRAPELLLNSSDYTAAIDVWSVGCIFMELMDRKPLFPGRD 268
Query: 301 DIDQGHVIFKLMGTPSMDEWGLAYHLPGSELTK--TNYKSTLQERFSKALNETGXXXXXX 358
+ Q ++ +L+GTPS +E + + + ++ ++F ++
Sbjct: 269 HVHQLRLLMELIGTPSEEELEFLNENAKRYIRQLPPYPRQSITDKF-PTVHPLAIDLIEK 327
Query: 359 XXXXDPYKRVTAMKAKKHPF 378
DP +R+T + A HP+
Sbjct: 328 MLTFDPRRRITVLDALAHPY 347
>At1g10210 [T] KOG0660 Mitogen-activated protein kinase
Length = 370
Score = 135 bits (341), Expect = 1e-31
Identities = 100/376 (26%), Positives = 172/376 (45%), Gaps = 45/376 (11%)
Query: 55 YREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNHKNI 114
Y + +G+G +G V ++ TN KVAIK+I E + + RE+ +L+ + H+N+
Sbjct: 32 YMPIKPIGRGAYGVVCSSVNSDTNEKVAIKKIHNVYENRIDALRTLRELKLLRHLRHENV 91
Query: 115 VKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGLLH 174
+ L +++ P K ++ K +++ M +DL ++
Sbjct: 92 IALKDVMM---PIHK-----------------------MSFKDVYLVYELMDTDLHQIIK 125
Query: 175 NPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLARNYY 234
+ +V + + QLL G+ YIH LHRD+K N+L++ +KI DFGLAR
Sbjct: 126 SSQV-LSNDHCQYFLFQLLRGLKYIHSANILHRDLKPGNLLVNANCDLKICDFGLAR--- 181
Query: 235 GSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFEKKP 294
N K G T VVTRWYRAPE++L +Y T++D+W +GC+FAE +KP
Sbjct: 182 --ASNTK-------GQFMTEYVVTRWYRAPELLLCCDNYGTSIDVWSVGCIFAELLGRKP 232
Query: 295 ILQGQTDIDQGHVIFKLMGTPSMDEWGLAYHLPGSELTKT-NYKSTLQ-ERFSKALNETG 352
I QG ++Q +I ++G+ ++ + ++ Y + R +
Sbjct: 233 IFQGTECLNQLKLIVNILGSQREEDLEFIDNPKAKRYIRSLPYSPGMSLSRLYPGAHVLA 292
Query: 353 XXXXXXXXXXDPYKRVTAMKAKKHPFF--FEEPLPNAQLTLPNEECHESDIKR--YKSEM 408
DP KR++ +A +HP+ +P N +P + + D++ + M
Sbjct: 293 IDLLQKMLVFDPSKRISVSEALQHPYMAPLYDPNANPPAQVPIDLDVDEDLREEMIREMM 352
Query: 409 NESMSQRPPSAPTGHT 424
M P A T +T
Sbjct: 353 WNEMLHYHPQASTLNT 368
>Hs20986501 [T] KOG0660 Mitogen-activated protein kinase
Length = 816
Score = 135 bits (339), Expect = 3e-31
Identities = 93/332 (28%), Positives = 150/332 (45%), Gaps = 44/332 (13%)
Query: 53 NNYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNHK 112
+ Y E +G G +G V T ++VAIK+I + RE+ ILK H
Sbjct: 53 DEYEIIETIGNGAYGVVSSARRRLTGQQVAIKKIPNAFDVVTNAKRTLRELKILKHFKHD 112
Query: 113 NIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGL 172
NI+ + +I+ PT P G + K +++L M SDL +
Sbjct: 113 NIIAIKDIL---RPTV--------PYGEF--------------KSVYVVLDLMESDLHQI 147
Query: 173 LHNPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLARN 232
+H+ + + V+ + QLL G+ Y+H + +HRD+K +N+L++ +KI DFG+AR
Sbjct: 148 IHSSQ-PLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIGDFGMARG 206
Query: 233 YYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFEK 292
SP +Y T V TRWYRAPE++L YT A+D+W +GC+F E +
Sbjct: 207 LCTSPAEHQY--------FMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLAR 258
Query: 293 KPILQGQTDIDQGHVIFKLMGTPSMDEWGLAYHLPGSELTKTNYKS------TLQERFSK 346
+ + G+ + Q +I ++GTPS G+E + +S E
Sbjct: 259 RQLFPGKNYVHQLQLIMMVLGTPS----PAVIQAVGAERVRAYIQSLPPRQPVPWETVYP 314
Query: 347 ALNETGXXXXXXXXXXDPYKRVTAMKAKKHPF 378
+ +P R++A A +HPF
Sbjct: 315 GADRQALSLLGRMLRFEPSARISAAAALRHPF 346
>Hs20986497 [T] KOG0660 Mitogen-activated protein kinase
Length = 816
Score = 135 bits (339), Expect = 3e-31
Identities = 93/332 (28%), Positives = 150/332 (45%), Gaps = 44/332 (13%)
Query: 53 NNYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNHK 112
+ Y E +G G +G V T ++VAIK+I + RE+ ILK H
Sbjct: 53 DEYEIIETIGNGAYGVVSSARRRLTGQQVAIKKIPNAFDVVTNAKRTLRELKILKHFKHD 112
Query: 113 NIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGL 172
NI+ + +I+ PT P G + K +++L M SDL +
Sbjct: 113 NIIAIKDIL---RPTV--------PYGEF--------------KSVYVVLDLMESDLHQI 147
Query: 173 LHNPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLARN 232
+H+ + + V+ + QLL G+ Y+H + +HRD+K +N+L++ +KI DFG+AR
Sbjct: 148 IHSSQ-PLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIGDFGMARG 206
Query: 233 YYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFEK 292
SP +Y T V TRWYRAPE++L YT A+D+W +GC+F E +
Sbjct: 207 LCTSPAEHQY--------FMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLAR 258
Query: 293 KPILQGQTDIDQGHVIFKLMGTPSMDEWGLAYHLPGSELTKTNYKS------TLQERFSK 346
+ + G+ + Q +I ++GTPS G+E + +S E
Sbjct: 259 RQLFPGKNYVHQLQLIMMVLGTPS----PAVIQAVGAERVRAYIQSLPPRQPVPWETVYP 314
Query: 347 ALNETGXXXXXXXXXXDPYKRVTAMKAKKHPF 378
+ +P R++A A +HPF
Sbjct: 315 GADRQALSLLGRMLRFEPSARISAAAALRHPF 346
>CE18608 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 342
Score = 135 bits (339), Expect = 3e-31
Identities = 89/353 (25%), Positives = 163/353 (45%), Gaps = 47/353 (13%)
Query: 32 LEYIQVQSRENEKVYGVTK---FLNNYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILV 88
+E +++Q N G + +++ + LG+G +G V++ L + A+K+I++
Sbjct: 12 MEILRLQKMMNNMTCGQMAKPLTMKDFQIHQALGKGAYGNVYRVRSLHDGKDYALKQIMI 71
Query: 89 RAEKDLFPITAQREITILK---RMNHKNIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNN 145
++ + P + REIT++K R H NI+ L + + P +
Sbjct: 72 SSKNEGIPQSVLREITVMKHLARKAHPNIISLKSVFHQLDPVRAILKIN----------- 120
Query: 146 TANQQKLITGKHFFMILPYMVSDLTGLLHNPRVEFGMADVKNIMLQLLEGINYIHCNKFL 205
MI+ DL L N K++ Q++ ++++H + +
Sbjct: 121 --------------MIMERCDWDLHTFLRNIPRGVPEQQAKHVTAQIVRALDFLHTHSII 166
Query: 206 HRDIKTANILIDHKGVVKIADFGLARNYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPE 265
HRD+K NIL++ VK+ADFGL++ Y + +T++VVT WYR+PE
Sbjct: 167 HRDLKPQNILLNRDQTVKLADFGLSKEYSNT-------------TAFTTLVVTLWYRSPE 213
Query: 266 IVLGDRHYTTAVDIWGIGCVFAEFFEKKPILQGQTDIDQGHVIFKLMGTPSMDEWGLAYH 325
++L +Y + VD+W +GC+ +E + ++P+ GQ + +Q IFK MGTP +W
Sbjct: 214 VLL-QSYYNSTVDMWALGCIVSEIYCRQPLFVGQNEAEQLTDIFKKMGTPVGKDWPSESV 272
Query: 326 LPGSELTKTNYKSTLQERFSKALNETGXXXXXXXXXXDPYKRVTAMKAKKHPF 378
+ + Y+ T + S +++ D KR++A A HPF
Sbjct: 273 IARDSFPQ--YRPTNLKDLSPQMSKQAIEFVQQCLRYDHSKRLSARGALSHPF 323
>At3g45640 [T] KOG0660 Mitogen-activated protein kinase
Length = 370
Score = 134 bits (336), Expect = 6e-31
Identities = 87/337 (25%), Positives = 150/337 (43%), Gaps = 49/337 (14%)
Query: 61 LGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNHKNIVKLIEI 120
+G+G +G V + TN VA+K+I + + REI +L+ ++H+NI+ + ++
Sbjct: 44 IGRGAYGIVCSVLDTETNELVAMKKIANAFDNHMDAKRTLREIKLLRHLDHENIIAIRDV 103
Query: 121 VYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGLLHNPRVEF 180
V P P+ + + + + T H + +S+
Sbjct: 104 V-------------PPPLRRQFSDVYISTELMDTDLHQIIRSNQSLSE------------ 138
Query: 181 GMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLARNYYGSPPNL 240
+ + QLL G+ YIH +HRD+K +N+L++ +KI DFGLAR
Sbjct: 139 --EHCQYFLYQLLRGLKYIHSANIIHRDLKPSNLLLNANCDLKICDFGLARP-------- 188
Query: 241 KYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFEKKPILQGQT 300
T VVTRWYRAPE++L YT A+D+W +GC+F E +KP+ G+
Sbjct: 189 -----TSENDFMTEYVVTRWYRAPELLLNSSDYTAAIDVWSVGCIFMELMNRKPLFPGKD 243
Query: 301 DIDQGHVIFKLMGTPSMDEWGLAYHLPGSELTK--TNYKSTLQERFSKALNETGXXXXXX 358
+ Q ++ +L+GTP+ + G ++ + N+ + +N
Sbjct: 244 HVHQMRLLTELLGTPTESDLGFTHNEDAKRYIRQLPNFPRQPLAKLFSHVNPMAIDLVDR 303
Query: 359 XXXXDPYKRVTAMKAKKHPFFFEEPLPNAQLTLPNEE 395
DP +R+T +A H + A+L PN+E
Sbjct: 304 MLTFDPNRRITVEQALNHQYL-------AKLHDPNDE 333
>7297009 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 392
Score = 133 bits (335), Expect = 7e-31
Identities = 102/335 (30%), Positives = 146/335 (43%), Gaps = 53/335 (15%)
Query: 52 LNNYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNH 111
++ Y + +LG+G++G V+K T VA+KR + + A REI +LK + H
Sbjct: 1 MDRYEKLSRLGEGSYGVVYKCRDRETGALVAVKRFVESEDDPAIRKIALREIRLLKNLKH 60
Query: 112 KNIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTG 171
N+V L+E+ R H L + +LT
Sbjct: 61 PNLVSLLEVF--------------RRKRRLH-------------------LVFEFCELTV 87
Query: 172 LLHNPRVEFGMAD--VKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGL 229
L R G + K I Q L G+ Y H LHRDIK NIL+ +G VK+ DFG
Sbjct: 88 LHELERHPQGCPEHLTKQICYQTLLGVAYCHKQGCLHRDIKPENILLTAQGQVKLCDFGF 147
Query: 230 ARNYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEF 289
AR SP G YT V TRWYRAPE+++GD Y T VD+W IGC+FAE
Sbjct: 148 ARML--SP-----------GENYTDYVATRWYRAPELLVGDTQYGTPVDVWAIGCLFAEL 194
Query: 290 FEKKPILQGQTDIDQGHVIFKLMG---TPSMDEWGLAYHLPGSELTKTNYKSTLQERF-- 344
+ + G++D+DQ ++I K +G + +G + G L L+++
Sbjct: 195 VRGEALWPGRSDVDQLYLIRKTLGDLLPRHIQIFGQNEYFKGITLPVPPTLEPLEDKMPA 254
Query: 345 SKALNETGXXXXXXXXXXDPYKRVTAMKAKKHPFF 379
N DP KR + K KH +F
Sbjct: 255 KSQQNPLTIDFLKKCLDKDPTKRWSCEKLTKHSYF 289
>CE28918 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 406
Score = 133 bits (334), Expect = 1e-30
Identities = 85/323 (26%), Positives = 151/323 (46%), Gaps = 44/323 (13%)
Query: 59 EKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILK---RMNHKNIV 115
+ LG+G +G V++ L + A+K+I++ ++ + P + REIT++K R H NI+
Sbjct: 106 QALGKGAYGNVYRVRSLHDGKDYALKQIMISSKNEGIPQSVLREITVMKHLARKAHPNII 165
Query: 116 KLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGLLHN 175
L + + P + MI+ DL L N
Sbjct: 166 SLKSVFHQLDPVRAILKIN-------------------------MIMERCDWDLHTFLRN 200
Query: 176 PRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLARNYYG 235
K++ Q++ ++++H + +HRD+K NIL++ VK+ADFGL++ Y
Sbjct: 201 IPRGVPEQQAKHVTAQIVRALDFLHTHSIIHRDLKPQNILLNRDQTVKLADFGLSKEYSN 260
Query: 236 SPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFEKKPI 295
+ +T++VVT WYR+PE++L +Y + VD+W +GC+ +E + ++P+
Sbjct: 261 T-------------TAFTTLVVTLWYRSPEVLL-QSYYNSTVDMWALGCIVSEIYCRQPL 306
Query: 296 LQGQTDIDQGHVIFKLMGTPSMDEWGLAYHLPGSELTKTNYKSTLQERFSKALNETGXXX 355
GQ + +Q IFK MGTP +W + + Y+ T + S +++
Sbjct: 307 FVGQNEAEQLTDIFKKMGTPVGKDWPSESVIARDSFPQ--YRPTNLKDLSPQMSKQAIEF 364
Query: 356 XXXXXXXDPYKRVTAMKAKKHPF 378
D KR++A A HPF
Sbjct: 365 VQQCLRYDHSKRLSARGALSHPF 387
>7295173 [T] KOG0664 Nemo-like MAPK-related serine/threonine protein kinase
Length = 474
Score = 132 bits (332), Expect = 2e-30
Identities = 93/328 (28%), Positives = 155/328 (46%), Gaps = 43/328 (13%)
Query: 58 EEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNHKNIVKL 117
+ +G G FG V+ R+VA+K++ + + RE+ +L H+N++
Sbjct: 43 DRPIGYGAFGVVWAVTDPRDGRRVALKKLPNVFQSLVSSKRVFRELKMLCFFKHENVLSA 102
Query: 118 IEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGLLHNPR 177
++I+ P D + ++I + SDL ++ +P+
Sbjct: 103 LDILQP----PHLDFF----------------------QEIYVITELLQSDLHKIIVSPQ 136
Query: 178 VEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLARNYYGSP 237
+K + Q+L G+ Y+H + LHRDIK N+L++ V+KI DFGLAR P
Sbjct: 137 -HLSADHIKVFLYQILRGLKYLHSARILHRDIKPGNLLVNSNCVLKICDFGLAR--VEEP 193
Query: 238 PNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFEKKPILQ 297
K+ T VVT++YRAPEI++G RHY++AVD+W +GC+F E ++ + Q
Sbjct: 194 DQAKH---------MTQEVVTQYYRAPEILMGARHYSSAVDVWSVGCIFGELLGRRILFQ 244
Query: 298 GQTDIDQGHVIFKLMGTPSMDEWGLAYHLPGSELTKTNYK----STLQERFSKALNETGX 353
Q + Q +I +L+GTP+M++ A + + + K S L S A +E
Sbjct: 245 AQNPVQQLELITELLGTPTMEDMRHACEGARTHMLRRAPKPPSFSVLYTLSSHATHE-AV 303
Query: 354 XXXXXXXXXDPYKRVTAMKAKKHPFFFE 381
DP KR++ A HP+ E
Sbjct: 304 HLLCQMLVFDPDKRISVTDALAHPYLDE 331
>CE29478 [T] KOG0664 Nemo-like MAPK-related serine/threonine protein kinase
Length = 437
Score = 132 bits (331), Expect = 2e-30
Identities = 89/329 (27%), Positives = 150/329 (45%), Gaps = 43/329 (13%)
Query: 58 EEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNHKNIVKL 117
+ +G G FG V+ + ++VA+K++ + REI +L H N++ L
Sbjct: 46 DRPIGYGAFGVVWSVTDPRSGKRVALKKMPNVFQNLASCKRVFREIKMLSSFRHDNVLSL 105
Query: 118 IEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGLLHNPR 177
++I+ +P+ + +++ M SDL ++ +P+
Sbjct: 106 LDILQPANPS--------------------------FFQELYVLTELMQSDLHKIIVSPQ 139
Query: 178 VEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLARNYYGSP 237
VK + Q+L G+ Y+H LHRDIK N+L++ ++KI DFGLAR +
Sbjct: 140 A-LTPDHVKVFVYQILRGLKYLHTANILHRDIKPGNLLVNSNCILKICDFGLARTW---- 194
Query: 238 PNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFEKKPILQ 297
T VVT++YRAPE+++G R YT AVDIW +GC+FAE ++K + Q
Sbjct: 195 -------DQRDRLNMTHEVVTQYYRAPELLMGARRYTGAVDIWSVGCIFAELLQRKILFQ 247
Query: 298 GQTDIDQGHVIFKLMGTPSMDEWGLAYHLPGSELTKTNYKSTLQERFSKAL-----NETG 352
I+Q +I L+GTPS + A + + + ++ +R K N
Sbjct: 248 AAGPIEQLQMIIDLLGTPSQEAMKYACEGAKNHVLRAGLRAPDTQRLYKIASPDDKNHEA 307
Query: 353 XXXXXXXXXXDPYKRVTAMKAKKHPFFFE 381
DP KR++ +A +H + E
Sbjct: 308 VDLLQKLLHFDPDKRISVEEALQHRYLEE 336
>CE29477 [T] KOG0664 Nemo-like MAPK-related serine/threonine protein kinase
Length = 462
Score = 132 bits (331), Expect = 2e-30
Identities = 89/329 (27%), Positives = 150/329 (45%), Gaps = 43/329 (13%)
Query: 58 EEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNHKNIVKL 117
+ +G G FG V+ + ++VA+K++ + REI +L H N++ L
Sbjct: 71 DRPIGYGAFGVVWSVTDPRSGKRVALKKMPNVFQNLASCKRVFREIKMLSSFRHDNVLSL 130
Query: 118 IEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGLLHNPR 177
++I+ +P+ + +++ M SDL ++ +P+
Sbjct: 131 LDILQPANPS--------------------------FFQELYVLTELMQSDLHKIIVSPQ 164
Query: 178 VEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLARNYYGSP 237
VK + Q+L G+ Y+H LHRDIK N+L++ ++KI DFGLAR +
Sbjct: 165 A-LTPDHVKVFVYQILRGLKYLHTANILHRDIKPGNLLVNSNCILKICDFGLARTW---- 219
Query: 238 PNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFEKKPILQ 297
T VVT++YRAPE+++G R YT AVDIW +GC+FAE ++K + Q
Sbjct: 220 -------DQRDRLNMTHEVVTQYYRAPELLMGARRYTGAVDIWSVGCIFAELLQRKILFQ 272
Query: 298 GQTDIDQGHVIFKLMGTPSMDEWGLAYHLPGSELTKTNYKSTLQERFSKAL-----NETG 352
I+Q +I L+GTPS + A + + + ++ +R K N
Sbjct: 273 AAGPIEQLQMIIDLLGTPSQEAMKYACEGAKNHVLRAGLRAPDTQRLYKIASPDDKNHEA 332
Query: 353 XXXXXXXXXXDPYKRVTAMKAKKHPFFFE 381
DP KR++ +A +H + E
Sbjct: 333 VDLLQKLLHFDPDKRISVEEALQHRYLEE 361
>CE29476 [T] KOG0664 Nemo-like MAPK-related serine/threonine protein kinase
Length = 634
Score = 132 bits (331), Expect = 2e-30
Identities = 89/329 (27%), Positives = 150/329 (45%), Gaps = 43/329 (13%)
Query: 58 EEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNHKNIVKL 117
+ +G G FG V+ + ++VA+K++ + REI +L H N++ L
Sbjct: 243 DRPIGYGAFGVVWSVTDPRSGKRVALKKMPNVFQNLASCKRVFREIKMLSSFRHDNVLSL 302
Query: 118 IEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGLLHNPR 177
++I+ +P+ + +++ M SDL ++ +P+
Sbjct: 303 LDILQPANPS--------------------------FFQELYVLTELMQSDLHKIIVSPQ 336
Query: 178 VEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLARNYYGSP 237
VK + Q+L G+ Y+H LHRDIK N+L++ ++KI DFGLAR +
Sbjct: 337 A-LTPDHVKVFVYQILRGLKYLHTANILHRDIKPGNLLVNSNCILKICDFGLARTW---- 391
Query: 238 PNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFEKKPILQ 297
T VVT++YRAPE+++G R YT AVDIW +GC+FAE ++K + Q
Sbjct: 392 -------DQRDRLNMTHEVVTQYYRAPELLMGARRYTGAVDIWSVGCIFAELLQRKILFQ 444
Query: 298 GQTDIDQGHVIFKLMGTPSMDEWGLAYHLPGSELTKTNYKSTLQERFSKAL-----NETG 352
I+Q +I L+GTPS + A + + + ++ +R K N
Sbjct: 445 AAGPIEQLQMIIDLLGTPSQEAMKYACEGAKNHVLRAGLRAPDTQRLYKIASPDDKNHEA 504
Query: 353 XXXXXXXXXXDPYKRVTAMKAKKHPFFFE 381
DP KR++ +A +H + E
Sbjct: 505 VDLLQKLLHFDPDKRISVEEALQHRYLEE 533
>At4g36450 [T] KOG0660 Mitogen-activated protein kinase
Length = 361
Score = 132 bits (331), Expect = 2e-30
Identities = 91/324 (28%), Positives = 149/324 (45%), Gaps = 52/324 (16%)
Query: 61 LGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNHKNIVKLIEI 120
+G+G +G V I+ TN +VAIK+I E + + RE+ +L+ + H+N++ L ++
Sbjct: 38 IGRGAYGVVCSSINSETNERVAIKKIHNVFENRIDALRTLRELKLLRHVRHENVISLKDV 97
Query: 121 VYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGLLHNPRVEF 180
+ P Y + + +++ M SDL ++ + +
Sbjct: 98 ML--------------PTHRY------------SFRDVYLVYELMDSDLNQIIKSSQ--- 128
Query: 181 GMAD--VKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLARNYYGSPP 238
++D K + QLL G+ Y+H LHRD+K N+L++ +KI DFGLAR Y
Sbjct: 129 SLSDDHCKYFLFQLLRGLKYLHSANILHRDLKPGNLLVNANCDLKICDFGLARTYEQF-- 186
Query: 239 NLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFEKKPILQG 298
T VVTRWYRAPE++L +Y T++D+W +GC+FAE +KPI G
Sbjct: 187 -------------MTEYVVTRWYRAPELLLCCDNYGTSIDVWSVGCIFAEILGRKPIFPG 233
Query: 299 QTDIDQGHVIFKLMGTPSMDEWGLAY--HLPGSELTKT--NYKSTLQERFSKALNETGXX 354
++Q +I ++G S +W L + + K+ K T N
Sbjct: 234 TECLNQLKLIINVVG--SQQDWDLQFIDNQKARRFIKSLPFSKGTHFSHIYPHANPLAID 291
Query: 355 XXXXXXXXDPYKRVTAMKAKKHPF 378
DP KR++ A HP+
Sbjct: 292 LLQRMLVFDPTKRISVSDALLHPY 315
>At1g59580 [T] KOG0660 Mitogen-activated protein kinase
Length = 376
Score = 131 bits (330), Expect = 3e-30
Identities = 90/336 (26%), Positives = 155/336 (45%), Gaps = 43/336 (12%)
Query: 61 LGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNHKNIVKLIEI 120
+G+G +G V ++ +N +VAIK+I E + + RE+ +L+ + H+N+V L ++
Sbjct: 38 IGRGAYGVVCSSVNRESNERVAIKKIHNVFENRIDALRTLRELKLLRHLRHENVVALKDV 97
Query: 121 VYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGLLHNPRVEF 180
+ AN ++ K +++ M +DL ++ + +V
Sbjct: 98 MM------------------------ANHKRSF--KDVYLVYELMDTDLHQIIKSSQV-L 130
Query: 181 GMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLARNYYGSPPNL 240
+ + QLL G+ YIH LHRD+K N+L++ +KI DFGLAR N
Sbjct: 131 SNDHCQYFLFQLLRGLKYIHSANILHRDLKPGNLLVNANCDLKICDFGLART-----SNT 185
Query: 241 KYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFEKKPILQGQT 300
K G T VVTRWYRAPE++L +Y T++D+W +GC+FAE +KP+ G
Sbjct: 186 K-------GQFMTEYVVTRWYRAPELLLCCDNYGTSIDVWSVGCIFAELLGRKPVFPGTE 238
Query: 301 DIDQGHVIFKLMGTPSMDEWGLAYHLPGSE-LTKTNYKSTLQ-ERFSKALNETGXXXXXX 358
++Q +I ++G+ ++ + + Y + R N
Sbjct: 239 CLNQIKLIINILGSQREEDLEFIDNPKAKRYIESLPYSPGISFSRLYPGANVLAIDLLQK 298
Query: 359 XXXXDPYKRVTAMKAKKHPFF--FEEPLPNAQLTLP 392
DP KR++ +A +HP+ +P N +P
Sbjct: 299 MLVLDPSKRISVTEALQHPYMAPLYDPSANPPAQVP 334
>CE17815 [K] KOG0666 Cyclin C-dependent kinase CDK8
Length = 622
Score = 131 bits (329), Expect = 4e-30
Identities = 101/362 (27%), Positives = 159/362 (43%), Gaps = 76/362 (20%)
Query: 55 YREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRA-EKDLFPITAQREITILKRMNHKN 113
+ +++G+GT+G V+K + N + K ++ E F ++A REI + + + H N
Sbjct: 26 FENSKEIGRGTYGLVYKAVPKKQNGQFPNKEYALKMIEGQGFSMSACREIALFRELRHPN 85
Query: 114 IVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGLL 173
++ L + L K +++L Y DL ++
Sbjct: 86 LICLQRVF------------------------------LTNEKKVWLLLDYAEHDLWHVI 115
Query: 174 HNPR--------VEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILI------DHK 219
+ R + VKNI+ Q+L G++Y+H N LHRD+K ANIL+ D +
Sbjct: 116 KHHRTAKSKKVPIMVPRNMVKNILFQILSGMHYLHSNWVLHRDLKPANILLMGDGPPDMR 175
Query: 220 GVVKIADFGLARNYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDI 279
G VKIAD G +R Y + A+ VVVT WYRAPE++LG +HYT A+D+
Sbjct: 176 GRVKIADLGFSRIYANPLKPM---------AELDPVVVTFWYRAPELLLGAKHYTKAIDV 226
Query: 280 WGIGCVFAEFFEKKPIL---------QGQTDIDQGHVIFKLMGTPSMDEWGLAYHLPGSE 330
W IGC+FAE +P+ Q DQ IF L+G PS +W +P +
Sbjct: 227 WAIGCIFAELLTAEPLFFCKEEDIKAQNPYHYDQVKRIFHLLGYPSDADWPDMKKMPDHQ 286
Query: 331 --LTKTNYKSTLQERFSKALN-----------ETGXXXXXXXXXXDPYKRVTAMKAKKHP 377
L+ + T + F +L+ + DP KRV+ +A
Sbjct: 287 RLLSDARNEGTPIQTFPNSLHRYFDKWKINSQSSPYRLLVKLLTVDPTKRVSCEEAMNDI 346
Query: 378 FF 379
+F
Sbjct: 347 YF 348
>Hs7106269 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 452
Score = 130 bits (328), Expect = 5e-30
Identities = 92/336 (27%), Positives = 143/336 (42%), Gaps = 67/336 (19%)
Query: 60 KLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNHKNIVKLIE 119
++G+G G VFK H+ T +A+K++ +R +D FP A REI L+ M V ++
Sbjct: 9 RIGEGAHGIVFKAKHVETGEIIALKKVALRRLEDGFPNQALREIKALQEMEDNQYVVQLK 68
Query: 120 IVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGLLHNPRVE 179
V+ HG F + +M+SDL ++ + +
Sbjct: 69 AVFP------------------HGGG------------FVLAFEFMLSDLAEVVRHAQRP 98
Query: 180 FGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLARNYYGSPPN 239
A VK+ + LL+G+ + H N +HRD+K AN+LI G +KIADFGLAR + SP
Sbjct: 99 LAQAQVKSYLQMLLKGVAFCHANNIVHRDLKPANLLISASGQLKIADFGLARVF--SPD- 155
Query: 240 LKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFEKKPILQGQ 299
G R YT V +GC+ E P+ G+
Sbjct: 156 -----------------------------GSRLYTHQVATRSVGCIMGELLNGSPLFPGK 186
Query: 300 TDIDQGHVIFKLMGTPSMDEWGLAYHLPGSELTKTNYKSTLQERFSKALNET---GXXXX 356
DI+Q + +++GTP+ W LP + K ++K + + L +
Sbjct: 187 NDIEQLCYVLRILGTPNPQVWPELTELP--DYNKISFKEQVPMPLEEVLPDVSPQALDLL 244
Query: 357 XXXXXXDPYKRVTAMKAKKHPFFFEEPLPNAQLTLP 392
P++R+ A KA H +FF PLP LP
Sbjct: 245 GQFLLYPPHQRIAASKALLHQYFFTAPLPAHPSELP 280
>Hs7657498 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 419
Score = 130 bits (327), Expect = 6e-30
Identities = 96/332 (28%), Positives = 146/332 (43%), Gaps = 45/332 (13%)
Query: 52 LNNYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMN- 110
+ NY+ K+G+GTF EV K L A K++ R E + + REI L+R+N
Sbjct: 1 MKNYKAIGKIGEGTFSEVMKMQSLRDGNYYACKQMKQRFES-IEQVNNLREIQALRRLNP 59
Query: 111 HKNIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLT 170
H NI+ L E+V+D K+ S + +I M ++
Sbjct: 60 HPNILMLHEVVFDR----KSGSLA-------------------------LICELMDMNIY 90
Query: 171 GLLHNPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLA 230
L+ R + + M QL + +++IH N HRD+K NILI + V+K+ DFG
Sbjct: 91 ELIRGRRYPLSEKKIMHYMYQLCKSLDHIHRNGIFHRDVKPENILIK-QDVLKLGDFGSC 149
Query: 231 RNYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFF 290
R+ Y P YT + TRWYRAPE +L D YT +D+W GCVF E
Sbjct: 150 RSVYSKQP-------------YTEYISTRWYRAPECLLTDGFYTYKMDLWSAGCVFYEIA 196
Query: 291 EKKPILQGQTDIDQGHVIFKLMGTPSMDEWGLAYHLPGSELTKTNYKSTLQERFSKALNE 350
+P+ G ++DQ I ++GTP+ K + + L+
Sbjct: 197 SLQPLFPGVNELDQISKIHDVIGTPAQKILTKFKQSRAMNFDFPFKKGSGIPLLTTNLSP 256
Query: 351 TGXXXXXXXXXXDPYKRVTAMKAKKHPFFFEE 382
DP +R+ A +A +HP+F E+
Sbjct: 257 QCLSLLHAMVAYDPDERIAAHQALQHPYFQEQ 288
>Hs7706445 [T] KOG0664 Nemo-like MAPK-related serine/threonine protein kinase
Length = 515
Score = 130 bits (326), Expect = 8e-30
Identities = 92/328 (28%), Positives = 152/328 (46%), Gaps = 43/328 (13%)
Query: 58 EEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNHKNIVKL 117
+ +G G FG V+ ++VA+K++ + + RE+ +L H N++
Sbjct: 129 DRPIGYGAFGVVWSVTDPRDGKRVALKKMPNVFQNLVSCKRVFRELKMLCFFKHDNVLSA 188
Query: 118 IEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGLLHNPR 177
++I+ P + + + +++ M SDL ++ +P+
Sbjct: 189 LDIL------------QPPHIDYF--------------EEIYVVTELMQSDLHKIIVSPQ 222
Query: 178 VEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLARNYYGSP 237
VK + Q+L G+ Y+H LHRDIK N+L++ V+KI DFGLAR
Sbjct: 223 -PLSSDHVKVFLYQILRGLKYLHSAGILHRDIKPGNLLVNSNCVLKICDFGLAR------ 275
Query: 238 PNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFEKKPILQ 297
T VVT++YRAPEI++G RHY+ A+DIW +GC+FAE ++ + Q
Sbjct: 276 -----VEELDESRHMTQEVVTQYYRAPEILMGSRHYSNAIDIWSVGCIFAELLGRRILFQ 330
Query: 298 GQTDIDQGHVIFKLMGTPSMDEWGLAYHLPGSELTKTNYKS----TLQERFSKALNETGX 353
Q+ I Q +I L+GTPS++ A + + + +K L S+A +E
Sbjct: 331 AQSPIQQLDLITDLLGTPSLEAMRTACEGAKAHILRGPHKQPSLPVLYTLSSQATHE-AV 389
Query: 354 XXXXXXXXXDPYKRVTAMKAKKHPFFFE 381
DP KR++A A HP+ E
Sbjct: 390 HLLCRMLVFDPSKRISAKDALAHPYLDE 417
>Hs16936530 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 264
Score = 129 bits (325), Expect = 1e-29
Identities = 94/344 (27%), Positives = 159/344 (45%), Gaps = 86/344 (25%)
Query: 52 LNNYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNH 111
+ N+++ EK+G+GT+G V+K + T VA+K+I + E + P TA REI++LK +NH
Sbjct: 1 MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNH 60
Query: 112 KNIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTG 171
NIVKL+++++ E+ +++ ++ DL
Sbjct: 61 PNIVKLLDVIHTEN-------------------------------KLYLVFEFLHQDLKK 89
Query: 172 LLH-NPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLA 230
+ + + +K+ + QLL+G+ + H ++ LHRD+K N+LI+ +G +K+ADFGLA
Sbjct: 90 FMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLA 149
Query: 231 RNYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFF 290
R +G P R YT V
Sbjct: 150 R-AFGVPV--------------------------------RTYTHEV------------- 163
Query: 291 EKKPILQGQTDIDQGHVIFKLMGTPSMDEWGLAYHLPGSELTKTNYKSTLQERFSKA--- 347
++ + G ++IDQ IF+ +GTP W +P K ++ ++ FSK
Sbjct: 164 TRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPD---YKPSFPKWARQDFSKVVPP 220
Query: 348 LNETGXXXXXXXXXXDPYKRVTAMKAKKHPFFFE--EPLPNAQL 389
L+E G DPYKR++A A HPFF + +P+P+ +L
Sbjct: 221 LDEDGRSLLSQMLHYDPYKRISAKAALAHPFFQDVTKPVPHLRL 264
>CE06762 [T] KOG0660 Mitogen-activated protein kinase
Length = 367
Score = 129 bits (325), Expect = 1e-29
Identities = 91/327 (27%), Positives = 147/327 (44%), Gaps = 35/327 (10%)
Query: 55 YREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNHKNI 114
Y EE +G G +G V K + ++VAIK+I + RE+ IL+ + H+NI
Sbjct: 57 YLAEENVGAGAYGVVCKAMDTRNKKQVAIKKIPRAFTAHTLAKRSLREVRILRELLHENI 116
Query: 115 VKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGLLH 174
+ ++++ E GK ++++ M +DL +LH
Sbjct: 117 IAVLDMFTAEG---------------------------AHGKDIYLVMDLMETDLHQILH 149
Query: 175 NPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLARNYY 234
+ R + QLL G+ Y+H +HRD+K +N+L++ +++IADFG+AR Y
Sbjct: 150 S-RQTLMEQHFQYFFYQLLRGLKYLHSAGIIHRDLKPSNLLLNGDCLLRIADFGMARAYA 208
Query: 235 GSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFEKKP 294
+ A G T V TRWYRAPEI+ Y T VD+W GC+FAE ++
Sbjct: 209 SAS---TVRDDANVGGHMTQYVSTRWYRAPEILFSMVEYDTKVDLWSAGCIFAEMLLRRQ 265
Query: 295 ILQGQTDIDQGHVIFKLMGTPSMDEWG-LAYHLPGSELTKTNYKSTL--QERFSKALNET 351
+ G+ + Q +I +G+P + + L + K+ L F KA E
Sbjct: 266 LFPGKDSVSQIKMIVYYLGSPEEEVINRITSDLVRDSIEACGRKTPLPFSAIFPKASPE- 324
Query: 352 GXXXXXXXXXXDPYKRVTAMKAKKHPF 378
P+KR +A + +HPF
Sbjct: 325 ARNMVSYLLQISPWKRYSADQILQHPF 351
>At2g18170 [T] KOG0660 Mitogen-activated protein kinase
Length = 368
Score = 129 bits (325), Expect = 1e-29
Identities = 87/322 (27%), Positives = 148/322 (45%), Gaps = 45/322 (13%)
Query: 61 LGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNHKNIVKLIEI 120
+G+G +G V I+ TN +VAIK+I E + + RE+ +L+ + H+N++ L ++
Sbjct: 38 IGRGAYGVVCSSINRETNERVAIKKIHNVFENRVDALRTLRELKLLRHVRHENVIALKDV 97
Query: 121 VYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGLLHNPRVEF 180
+ AN+ K +++ M +DL ++ + +
Sbjct: 98 MLP-----------------------ANRSSF---KDVYLVYELMDTDLHQIIKSSQ--- 128
Query: 181 GMAD--VKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLARNYYGSPP 238
++D K + QLL G+ Y+H LHRD+K N+L++ +KI DFGLAR G+
Sbjct: 129 SLSDDHCKYFLFQLLRGLKYLHSANILHRDLKPGNLLVNANCDLKICDFGLARTSQGNEQ 188
Query: 239 NLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFEKKPILQG 298
+ T VVTRWYRAPE++L +Y T++D+W +GC+FAE +KPI G
Sbjct: 189 FM------------TEYVVTRWYRAPELLLCCDNYGTSIDVWSVGCIFAEILGRKPIFPG 236
Query: 299 QTDIDQGHVIFKLMGTPSMDEWGLAYHLPGSELTKT--NYKSTLQERFSKALNETGXXXX 356
++Q +I ++G+ + + K+ + T N
Sbjct: 237 TECLNQLKLIINVVGSQQESDIRFIDNPKARRFIKSLPYSRGTHLSNLYPQANPLAIDLL 296
Query: 357 XXXXXXDPYKRVTAMKAKKHPF 378
DP KR++ A HP+
Sbjct: 297 QRMLVFDPTKRISVTDALLHPY 318
>CE26988 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 308
Score = 129 bits (324), Expect = 1e-29
Identities = 91/346 (26%), Positives = 153/346 (43%), Gaps = 70/346 (20%)
Query: 55 YREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAE---KDLFPITAQREITILKRMNH 111
Y + LG+G F V+ L + VAIK+I + + KD TA REI +LK ++H
Sbjct: 5 YDTIKHLGEGQFANVYLAQDLESGECVAIKKIKLGSREEAKDGINRTAIREIKLLKEIHH 64
Query: 112 KNIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTG 171
NI+ L +++ G+ T+ Q ++ +M +DL
Sbjct: 65 DNIIGLRDVI---------------------GHRTSIQ----------LVFDFMDTDLEH 93
Query: 172 LLHNPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLAR 231
++ + + A +KNI +Q+L G+ ++H + LHRD+K N+L++ G
Sbjct: 94 VIKDKEIILMPAHIKNITMQMLLGLEFLHVHWILHRDLKPNNLLMNKMG----------- 142
Query: 232 NYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFE 291
VVTRWYRAPE++ G R Y +DIW +GC+ AE
Sbjct: 143 -----------------------RVVTRWYRAPELLFGARSYGVGIDIWSVGCIIAELLL 179
Query: 292 KKPILQGQTDIDQGHVIFKLMGTPSMDEWGLAYHLPGSELTKTNYKSTLQERFSKALNET 351
+ PI G++DIDQ IF ++G P+ + W + + K + + A +
Sbjct: 180 RNPIFPGESDIDQLVKIFNILGCPTPETWPNMTEMNSYVIIKPQTEYMALNYYFSAAPQD 239
Query: 352 GXXXXXXXXXXDPYKRVTAMKAKKHPFFFEEPL--PNAQLTLPNEE 395
DP KR+T ++ + +F +P + +L LP ++
Sbjct: 240 LLDLMAGMWTFDPIKRLTCTQSLQMEYFRTQPFCCLDEELPLPKKQ 285
>CE24971 [T] KOG0660 Mitogen-activated protein kinase
Length = 444
Score = 129 bits (324), Expect = 1e-29
Identities = 88/275 (32%), Positives = 136/275 (49%), Gaps = 39/275 (14%)
Query: 43 EKVYG-VTKFLNNYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQR 101
E+V+G + + Y +G+G +G V + T +VAIK+I E F R
Sbjct: 83 EEVHGQLFEVAPRYVNLSYIGEGAYGMVASALDTITRDRVAIKKISP-FEHQTFCQRTLR 141
Query: 102 EITILKRMNHKNIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMI 161
EI IL R H+NI+ + EI+ E+ DS K +++
Sbjct: 142 EIKILNRFKHENIINIQEIIRSET----VDSL----------------------KDIYIV 175
Query: 162 LPYMVSDLTGLLHNPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGV 221
M +DL LL ++ V + Q+L G+ YIH LHRD+K +N+L++
Sbjct: 176 QCLMETDLYKLLKTQKL--SNDHVCYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCD 233
Query: 222 VKIADFGLARNYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWG 281
+KI DFGLAR + P + G T V TRWYRAPEI+L + YT ++D+W
Sbjct: 234 LKICDFGLAR---VTDPQTDHTG------FLTEYVATRWYRAPEIMLNSKGYTKSIDVWS 284
Query: 282 IGCVFAEFFEKKPILQGQTDIDQGHVIFKLMGTPS 316
+GC+ AE +P+ G+ +DQ ++I ++G+PS
Sbjct: 285 VGCILAEMLSNRPLFPGKHYLDQLNLILAVVGSPS 319
>CE01583 [T] KOG0660 Mitogen-activated protein kinase
Length = 376
Score = 129 bits (324), Expect = 1e-29
Identities = 88/275 (32%), Positives = 136/275 (49%), Gaps = 39/275 (14%)
Query: 43 EKVYG-VTKFLNNYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQR 101
E+V+G + + Y +G+G +G V + T +VAIK+I E F R
Sbjct: 15 EEVHGQLFEVAPRYVNLSYIGEGAYGMVASALDTITRDRVAIKKISP-FEHQTFCQRTLR 73
Query: 102 EITILKRMNHKNIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMI 161
EI IL R H+NI+ + EI+ E+ DS K +++
Sbjct: 74 EIKILNRFKHENIINIQEIIRSET----VDSL----------------------KDIYIV 107
Query: 162 LPYMVSDLTGLLHNPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGV 221
M +DL LL ++ V + Q+L G+ YIH LHRD+K +N+L++
Sbjct: 108 QCLMETDLYKLLKTQKL--SNDHVCYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCD 165
Query: 222 VKIADFGLARNYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWG 281
+KI DFGLAR + P + G T V TRWYRAPEI+L + YT ++D+W
Sbjct: 166 LKICDFGLAR---VTDPQTDHTG------FLTEYVATRWYRAPEIMLNSKGYTKSIDVWS 216
Query: 282 IGCVFAEFFEKKPILQGQTDIDQGHVIFKLMGTPS 316
+GC+ AE +P+ G+ +DQ ++I ++G+PS
Sbjct: 217 VGCILAEMLSNRPLFPGKHYLDQLNLILAVVGSPS 251
>YGR040w [T] KOG0660 Mitogen-activated protein kinase
Length = 368
Score = 128 bits (321), Expect = 3e-29
Identities = 101/339 (29%), Positives = 160/339 (46%), Gaps = 50/339 (14%)
Query: 53 NNYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMN-H 111
+ Y+ + +G+G +G V IH + KVAIK+I ++K LF REI +L+ + H
Sbjct: 11 SQYKLVDLIGEGAYGTVCSAIHKPSGIKVAIKKIQPFSKK-LFVTRTIREIKLLRYFHEH 69
Query: 112 KNIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTG 171
+NI+ +++ V RPV N +++ M +DL
Sbjct: 70 ENIISILDKV--------------RPVSIDKLNAV------------YLVEELMETDLQK 103
Query: 172 LLHNPRVEFGMAD---VKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFG 228
+++N F V+ Q+L + IH + +HRDIK +N+L++ +K+ DFG
Sbjct: 104 VINNQNSGFSTLSDDHVQYFTYQILRALKSIHSAQVIHRDIKPSNLLLNSNCDLKVCDFG 163
Query: 229 LARNYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAE 288
LAR S + + G T V TRWYRAPEI+L + YTTA+DIW GC+ AE
Sbjct: 164 LARCLASSSDSRETLVGF-----MTEYVATRWYRAPEIMLTFQEYTTAMDIWSCGCILAE 218
Query: 289 FFEKKPILQGQTDIDQGHVIFKLMGTPSMDEWGLAYHLPGSELTKTNYKSTLQER----- 343
KP+ G+ Q +I +++GTPS +++ E Y + L R
Sbjct: 219 MVSGKPLFPGRDYHHQLWLILEVLGTPSFEDFNQIKSKRAKE-----YIANLPMRPPLPW 273
Query: 344 ---FSKA-LNETGXXXXXXXXXXDPYKRVTAMKAKKHPF 378
+SK LN +P KR++A +A +HP+
Sbjct: 274 ETVWSKTDLNPDMIDLLDKMLQFNPDKRISAAEALRHPY 312
>Hs20128774 [T] KOG0660 Mitogen-activated protein kinase
Length = 364
Score = 128 bits (321), Expect = 3e-29
Identities = 106/396 (26%), Positives = 170/396 (42%), Gaps = 72/396 (18%)
Query: 42 NEKVYGVTKFLNNYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQR 101
N+ V+ V + L R +G G +G V +KVA+K++ + + R
Sbjct: 14 NKTVWEVPQRLQGLRP---VGSGAYGSVCSAYDARLRQKVAVKKLSRPFQSLIHARRTYR 70
Query: 102 EITILKRMNHKNIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMI 161
E+ +LK + H+N++ L+++ TP T V +++
Sbjct: 71 ELRLLKHLKHENVIGLLDVF-----TPATSIEDFSEV--------------------YLV 105
Query: 162 LPYMVSDLTGL-----LHNPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILI 216
M +DL + L + V+F ++ QLL G+ YIH +HRD+K +N+ +
Sbjct: 106 TTLMGADLNNIVKCQALSDEHVQF-------LVYQLLRGLKYIHSAGIIHRDLKPSNVAV 158
Query: 217 DHKGVVKIADFGLARNYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTA 276
+ ++I DFGLAR + + T V TRWYRAPEI+L HY
Sbjct: 159 NEDCELRILDFGLARQ---------------ADEEMTGYVATRWYRAPEIMLNWMHYNQT 203
Query: 277 VDIWGIGCVFAEFFEKKPILQGQTDIDQGHVIFKLMGTPSMDEWGLAYHLPGSELTKTNY 336
VDIW +GC+ AE + K + G IDQ I +++GTPS + SE +T
Sbjct: 204 VDIWSVGCIMAELLQGKALFPGSDYIDQLKRIMEVVGTPSPEVLAKI----SSEHARTYI 259
Query: 337 KS-------TLQERFSKALNETGXXXXXXXXXXDPYKRVTAMKAKKHPFFFE----EPLP 385
+S L F + N D +RV+A +A H +F + E P
Sbjct: 260 QSLPPMPQKDLSSIF-RGANPLAIDLLGRMLVLDSDQRVSAAEALAHAYFSQYHDPEDEP 318
Query: 386 NAQLTLPNEECHESDIKRYKS-EMNESMSQRPPSAP 420
A+ + E E ++ +K E +S +PP P
Sbjct: 319 EAEPYDESVEAKERTLEEWKELTYQEVLSFKPPEPP 354
>Hs17461944 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 385
Score = 128 bits (321), Expect = 3e-29
Identities = 91/299 (30%), Positives = 143/299 (47%), Gaps = 45/299 (15%)
Query: 52 LNNYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNH 111
+ Y + K G+G++G VFK + + + VA+K+ + + + A REI +LK++ H
Sbjct: 1 MEKYEKLAKTGEGSYGVVFKCRNKTSGQVVAVKKFVESEDDPVVKKIALREIRMLKQLKH 60
Query: 112 KNIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTG 171
N+V LIE+ + + N N + G
Sbjct: 61 PNLVNLIEVFRRKRKMHLVFEYCDHTLLNELERNPNGMDS---------------DSIVG 105
Query: 172 LLHNPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLAR 231
L + +A KN + +L+ I HRDIK NILI +G++KI DFG A+
Sbjct: 106 RLRSVADRSRLAP-KNNQIMILQCI---------HRDIKPENILITKQGIIKICDFGFAQ 155
Query: 232 NYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFE 291
+ PG A YT V TRWYRAPE+++GD Y ++VDIW IGCVFAE
Sbjct: 156 --------ILIPGDA-----YTDYVATRWYRAPELLVGDTQYGSSVDIWAIGCVFAELLT 202
Query: 292 KKPILQGQTDIDQGHVIFKLMGT-----PSMDEWGLAYHLPGSELTKTNYKSTLQERFS 345
+P+ G++D+DQ ++I + +G S+ + +H G + + TL+E+FS
Sbjct: 203 GQPLWPGKSDVDQLYLIIRTLGKLIPRHQSIFKSNGFFH--GISIPEPEDMETLEEKFS 259
>CE21401 [G] KOG0658 Glycogen synthase kinase-3
Length = 362
Score = 128 bits (321), Expect = 3e-29
Identities = 101/349 (28%), Positives = 154/349 (43%), Gaps = 66/349 (18%)
Query: 54 NYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNHKN 113
+Y +++ +G G+FG VF TN VAIK++L RE+ I++++NH N
Sbjct: 35 SYYDQKVIGNGSFGVVFLAKLSTTNEMVAIKKVLQDKR------FKNRELQIMRKLNHPN 88
Query: 114 IVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGLL 173
IVKL Y S K D + Y +P V +
Sbjct: 89 IVKLKYFFY--SSGEKKDELYLNLILEY--------------------VPETVYRVARHY 126
Query: 174 HNPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILID-HKGVVKIADFGLARN 232
R + M VK M QLL + YIH HRDIK N+LID GV+K+ DFG A+
Sbjct: 127 SKQRQQIPMIYVKLYMYQLLRSLAYIHSIGICHRDIKPQNLLIDPESGVLKLCDFGSAKY 186
Query: 233 YYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFEK 292
+ PN+ Y + +R+YRAPE++ G +YT ++D+W G V AE
Sbjct: 187 LVRNEPNVSY-------------ICSRYYRAPELIFGATNYTNSIDVWSAGTVMAELLLG 233
Query: 293 KPILQGQTDIDQGHVIFKLMGTPSMDE------------WGLAYHLPGSELTKTNYKSTL 340
+PI G + +DQ I K++GTP+ ++ + P +++ + + +
Sbjct: 234 QPIFPGDSGVDQLVEIIKVLGTPTREQIQSMNPNYKEFKFPQIKAHPWNKVFRVHTPAEA 293
Query: 341 QERFSKALNETGXXXXXXXXXXDPYKRVTAMKAKKHPFFFEEPLPNAQL 389
+ SK + T P R T A +H FF E P+A+L
Sbjct: 294 IDLISKIIEYT------------PTSRPTPQAACQHAFFDELRNPDARL 330
>CE20258 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 353
Score = 128 bits (321), Expect = 3e-29
Identities = 84/264 (31%), Positives = 128/264 (47%), Gaps = 48/264 (18%)
Query: 52 LNNYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNH 111
++ Y KLG+G++G V+K + T + VAIK+ + + A REI +LK++ H
Sbjct: 1 MDKYDRLSKLGEGSYGVVYKCKNRDTGQIVAIKKFVETEDDPHIKKIALREIRMLKQLKH 60
Query: 112 KNIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTG 171
+N+V LIE+ +KL L + + D T
Sbjct: 61 QNLVGLIEVF-------------------------KRNRKLH--------LVFELCDRTV 87
Query: 172 LLHNPRVEFGMAD--VKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGL 229
L + G+ D +K I+ QLLE + + H +K +HRD+K NI + VK+ DFG
Sbjct: 88 LHELEKNPHGVNDELIKKIIYQLLEALKFCHSHKCIHRDVKPENIFLTRNDQVKLGDFGF 147
Query: 230 ARNYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEF 289
AR + YT V TRWYR+PE+++GD Y VDIW +GCV+AE
Sbjct: 148 ARII-------------NTTEMYTDYVATRWYRSPELLVGDVQYGPPVDIWAVGCVYAEL 194
Query: 290 FEKKPILQGQTDIDQGHVIFKLMG 313
+ + G++DIDQ + I K +G
Sbjct: 195 LTGEALWPGRSDIDQLYHIRKTLG 218
>Hs4506091 [T] KOG0660 Mitogen-activated protein kinase
Length = 721
Score = 127 bits (320), Expect = 4e-29
Identities = 102/354 (28%), Positives = 171/354 (47%), Gaps = 46/354 (12%)
Query: 53 NNYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNHK 112
+ Y + + LG G G VF + +++VAIK+I++ + + A REI I++R++H
Sbjct: 18 SRYMDLKPLGCGGNGLVFSAVDNDCDKRVAIKKIVLTDPQSVKH--ALREIKIIRRLDHD 75
Query: 113 NIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGL 172
NIVK+ EI+ S + TD VG+ N+ +++ YM +DL +
Sbjct: 76 NIVKVFEIL-GPSGSQLTDD-----VGSLTELNSV-----------YIVQEYMETDLANV 118
Query: 173 LHN-PRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVV-KIADFGLA 230
L P +E + M QLL G+ YIH LHRD+K AN+ I+ + +V KI DFGLA
Sbjct: 119 LEQGPLLE---EHARLFMYQLLRGLKYIHSANVLHRDLKPANLFINTEDLVLKIGDFGLA 175
Query: 231 RNYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFF 290
R P+ + G G +VT+WYR+P ++L +YT A+D+W GC+FAE
Sbjct: 176 RIM---DPHYSHKGHLSEG------LVTKWYRSPRLLLSPNNYTKAIDMWAAGCIFAEML 226
Query: 291 EKKPILQGQTDIDQGHVIFK-LMGTPSMDEWGLAYHLP---GSELTKTNYKSTLQERFSK 346
K + G +++Q +I + + D L +P +++T+ + T +
Sbjct: 227 TGKTLFAGAHELEQMQLILESIPVVHEEDRQELLSVIPVYIRNDMTEPHKPLT---QLLP 283
Query: 347 ALNETGXXXXXXXXXXDPYKRVTAMKAKKHPFF------FEEPLPNAQLTLPNE 394
++ P R+TA +A HP+ +EP+ + + +E
Sbjct: 284 GISREALDFLEQILTFSPMDRLTAEEALSHPYMSIYSFPMDEPISSHPFHIEDE 337
>YLR113w [T] KOG0660 Mitogen-activated protein kinase
Length = 435
Score = 127 bits (319), Expect = 5e-29
Identities = 102/353 (28%), Positives = 157/353 (43%), Gaps = 58/353 (16%)
Query: 30 TGLEYIQVQSRENEKVYG-VTKFLNNYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILV 88
T E+I+ Q ++G V + N Y + +G G FG V T++ VAIK+I+
Sbjct: 3 TNEEFIRTQ------IFGTVFEITNRYNDLNPVGMGAFGLVCSATDTLTSQPVAIKKIMK 56
Query: 89 RAEKDLFPITAQREITILKRMNHKNIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTAN 148
+ RE+ +LK + H+N++ L +I +P D
Sbjct: 57 PFSTAVLAKRTYRELKLLKHLRHENLICLQDIFL----SPLED----------------- 95
Query: 149 QQKLITGKHFFMILPYMVSDLTGLLHNPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRD 208
+ + +DL LL +E V+ + Q+L G+ Y+H +HRD
Sbjct: 96 ---------IYFVTELQGTDLHRLLQTRPLEKQF--VQYFLYQILRGLKYVHSAGVIHRD 144
Query: 209 IKTANILIDHKGVVKIADFGLARNYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVL 268
+K +NILI+ +KI DFGLAR ++ P + T V TR+YRAPEI+L
Sbjct: 145 LKPSNILINENCDLKICDFGLAR--------IQDP-------QMTGYVSTRYYRAPEIML 189
Query: 269 GDRHYTTAVDIWGIGCVFAEFFEKKPILQGQTDIDQGHVIFKLMGTPSMDEWG-LAYHLP 327
+ Y VDIW GC+FAE E KP+ G+ + Q +I L+G+P D +
Sbjct: 190 TWQKYDVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVINTICSENT 249
Query: 328 GSELTKTNYKSTL--QERFSKALNETGXXXXXXXXXXDPYKRVTAMKAKKHPF 378
+T ++ + ERF K + DP KR+TA A HP+
Sbjct: 250 LKFVTSLPHRDPIPFSERF-KTVEPDAVDLLEKMLVFDPKKRITAADALAHPY 301
>Hs20562757 [T] KOG0660 Mitogen-activated protein kinase
Length = 379
Score = 127 bits (319), Expect = 5e-29
Identities = 93/331 (28%), Positives = 150/331 (45%), Gaps = 50/331 (15%)
Query: 55 YREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNHKNI 114
Y + + +G+G +G V +VAIK+I E + REI IL R H+N+
Sbjct: 42 YTQLQYIGEGAYGMVSSAYDHVRKTRVAIKKISP-FEHQTYCQRTLREIQILLRFRHENV 100
Query: 115 VKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGLLH 174
+ + +I+ L + +++ M +DL LL
Sbjct: 101 IGIRDIL--------------------------RASTLEAMRDVYIVQDLMETDLYKLLK 134
Query: 175 NPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLARNYY 234
+ ++ + + Q+L G+ YIH LHRD+K +N+LI+ +KI DFGLAR
Sbjct: 135 SQQLSND--HICYFLYQILRGLKYIHSANVLHRDLKPSNLLINTTCDLKICDFGLARI-- 190
Query: 235 GSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFEKKP 294
+ P + G T V TRWYRAPEI+L + YT ++DIW +GC+ AE +P
Sbjct: 191 -ADPEHDHTGFL------TEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRP 243
Query: 295 ILQGQTDIDQGHVIFKLMGTPSMDEWGLAYHLPGSEL-------TKTNYKSTLQERFSKA 347
I G+ +DQ + I ++G+PS ++ ++ TK + + SKA
Sbjct: 244 IFPGKHYLDQLNHILGILGSPSQEDLNCIINMKARNYLQSLPSKTKVAWAKLFPKSDSKA 303
Query: 348 LNETGXXXXXXXXXXDPYKRVTAMKAKKHPF 378
L+ +P KR+T +A HP+
Sbjct: 304 LD-----LLDRMLTFNPNKRITVEEALAHPY 329
>ECU11g1290 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 328
Score = 127 bits (319), Expect = 5e-29
Identities = 95/325 (29%), Positives = 150/325 (45%), Gaps = 55/325 (16%)
Query: 52 LNNYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDL--FPITAQREITILKRM 109
+ NY + ++ G+FG V++ NR A+KR+ D F I RE+ ILK +
Sbjct: 23 IENYEKVCRISSGSFGNVYRVRRKTDNRVFALKRMNPSMCYDTNGFSILYIREVMILKHI 82
Query: 110 NHKNIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDL 169
H+NI+++ E+V FF+++ +DL
Sbjct: 83 RHRNIMEIEEVVEG-----------------------------CEINDFFIVMECCDTDL 113
Query: 170 TGLLHNPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGL 229
++H+ + GM + + Q+L+G+ ++H +HRD+K +NIL+ G ++IADFGL
Sbjct: 114 RSVIHSVG-KIGMKAARFLTCQMLKGLKFLHGAGIVHRDLKPSNILLMRDGGLRIADFGL 172
Query: 230 ARNYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEF 289
AR ++ T++VVT WYR EI+LG Y ++D+W +GCV E
Sbjct: 173 AR---------------AIESQMTNLVVTLWYRPIEILLGSETYDESIDMWSVGCVVGEM 217
Query: 290 FEKKPILQGQTDIDQGHVIFKLMGTPS-MDEWGLAYHLPGSELTKTNYKSTLQERFS--- 345
+PIL G+ ++DQ IF+L+G P+ D GL LP ST + F
Sbjct: 218 LRGEPILAGEGEMDQLDRIFRLLGYPTDADFEGL--DLP--HFKNIRRPSTFEASFEGDF 273
Query: 346 KALNETGXXXXXXXXXXDPYKRVTA 370
+ E DP KR TA
Sbjct: 274 ECYGEEAASFVRNLLSFDPRKRCTA 298
>CE08727 [G] KOG0658 Glycogen synthase kinase-3
Length = 367
Score = 127 bits (318), Expect = 7e-29
Identities = 93/338 (27%), Positives = 151/338 (44%), Gaps = 62/338 (18%)
Query: 61 LGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNHKNIVKLIEI 120
+G G+FG V+K + + +AIK+I V D F RE+TI+ M+H NI++L+
Sbjct: 43 IGTGSFGAVYKAVLRENDEPIAIKKIKV---DDRF---KSRELTIMHEMDHPNIIRLLYY 96
Query: 121 VYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLT----GLLHNP 176
+ N N ++ +M DL HN
Sbjct: 97 YVMQQ------------------ENCLN-----------FVMEFMPKDLAYVHRQFAHND 127
Query: 177 RVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDH-KGVVKIADFGLARNYYG 235
+ + +K M QLL GI ++H + +HRDIK N+L+D G++KI DFG A+
Sbjct: 128 K-QMPAYSIKLYMFQLLRGIGFLHLHNIVHRDIKPKNLLVDESNGILKICDFGSAKRLEK 186
Query: 236 SPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFEKKPI 295
+ PN+ Y + +R+YRAPE++ G ++Y T++D W +G V E PI
Sbjct: 187 NEPNITY-------------ICSRYYRAPELIFGSKNYDTSIDTWSVGTVVGELLHNSPI 233
Query: 296 LQGQTDIDQGHVIFKLMGTPS---MDEWGLAY-HLPGSELTKTNYKSTLQERFSKALNET 351
+ +D + K GTPS M +W Y H+P +T +Q+ + L+ +
Sbjct: 234 FLADSAVDILALQIKAFGTPSKEDMAKWNYEYVHIPYDTITGVG----IQKFIGRKLSLS 289
Query: 352 GXXXXXXXXXXDPYKRVTAMKAKKHPFFFEEPLPNAQL 389
DP R+ +A P+F + P+ +L
Sbjct: 290 TLELLNSLMKMDPKLRIKPYEALTLPYFDDLRDPHYKL 327
>CE02602_1 [T] KOG0660 Mitogen-activated protein kinase
Length = 342
Score = 127 bits (318), Expect = 7e-29
Identities = 77/261 (29%), Positives = 124/261 (47%), Gaps = 28/261 (10%)
Query: 55 YREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNHKNI 114
Y +E LG G FG V + I N++VAIK+I + A REI I + ++H+NI
Sbjct: 44 YLAQENLGAGAFGVVCRAIDSKLNKQVAIKKITRVFKNQSTAKCALREIRITRELSHENI 103
Query: 115 VKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGLLH 174
+ +++ ES + G+ ++++ M +DL +L
Sbjct: 104 INSTDVLMRESGS---------------------------GQDIYIVMDLMETDLLSVLK 136
Query: 175 NPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLARNYY 234
+ + + Q+L+G+ Y+H +HRD+K AN+L++ +KIADFG++R+
Sbjct: 137 SNQT-LNEKHFQYFFYQILKGLKYLHSAGIIHRDLKPANLLLNEDCSLKIADFGMSRSGP 195
Query: 235 GSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFEKKP 294
+ A + V T WYRAPEI+L Y T VDIW GC+ AE +P
Sbjct: 196 STKTTPNTSPNAHISGDLSQYVSTLWYRAPEILLSMGEYDTQVDIWSAGCILAEMLLLRP 255
Query: 295 ILQGQTDIDQGHVIFKLMGTP 315
I G Q ++ + +GTP
Sbjct: 256 IFTGTDSYSQIQLLIEYLGTP 276
>SPAC31G5.09c [T] KOG0660 Mitogen-activated protein kinase
Length = 372
Score = 126 bits (317), Expect = 9e-29
Identities = 88/321 (27%), Positives = 152/321 (46%), Gaps = 42/321 (13%)
Query: 61 LGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNHKNIVKLIEI 120
+GQG +G V +H + KVA+K+I +F + REI +L+ H+NI+ +++I
Sbjct: 45 IGQGAYGVVCAALHKPSGLKVAVKKIHP-FNHPVFCLRTLREIKLLRHFRHENIISILDI 103
Query: 121 VYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGLLHNPRVEF 180
+ P P + Q+L + +++ M +DL ++ + +
Sbjct: 104 L----PPP-------------------SYQEL---EDVYIVQELMETDLYRVIRSQPLSD 137
Query: 181 GMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLARNYYGSPPNL 240
Q+L + +H +HRD+K +N+L++ +K+ADFGLAR+
Sbjct: 138 DHCQY--FTYQILRALKAMHSAGVVHRDLKPSNLLLNANCDLKVADFGLARSTTAQ---- 191
Query: 241 KYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFEKKPILQGQT 300
G+ T V TRWYRAPEI+L R Y+ A+D+W GC+ AE +P+ G+
Sbjct: 192 -----GGNPGFMTEYVATRWYRAPEIMLSFREYSKAIDLWSTGCILAEMLSARPLFPGKD 246
Query: 301 DIDQGHVIFKLMGTPSMDEWGLAYHLPGSELTKT---NYKSTLQERFSKALNETGXXXXX 357
Q +I ++GTP+MD++ + K+ K + + F +A +
Sbjct: 247 YHSQITLILNILGTPTMDDFSRIKSARARKYIKSLPFTPKVSFKALFPQA-SPDAIDLLE 305
Query: 358 XXXXXDPYKRVTAMKAKKHPF 378
+P KR+TA +A KHP+
Sbjct: 306 KLLTFNPDKRITAEEALKHPY 326
>Hs20986512 [T] KOG0660 Mitogen-activated protein kinase
Length = 360
Score = 126 bits (317), Expect = 9e-29
Identities = 97/375 (25%), Positives = 166/375 (43%), Gaps = 59/375 (15%)
Query: 55 YREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNHKNI 114
Y+ +G G +G V T +VA+K++ + + RE+ +LK M H+N+
Sbjct: 24 YQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENV 83
Query: 115 VKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGLLH 174
+ L+++ T R + ++ +++ M +DL ++
Sbjct: 84 IGLLDVF-----------TPARSLEEFND--------------VYLVTHLMGADLNNIVK 118
Query: 175 NPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLARNYY 234
++ V+ ++ Q+L G+ YIH +HRD+K +N+ ++ +KI DFGLAR+
Sbjct: 119 CQKLTDD--HVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARH-- 174
Query: 235 GSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFEKKP 294
+ + T V TRWYRAPEI+L HY VDIW +GC+ AE +
Sbjct: 175 -------------TDDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRT 221
Query: 295 ILQGQTDIDQGHVIFKLMGTPSMD-------EWGLAYHLPGSELTKTNYKSTLQERFSKA 347
+ G IDQ +I +L+GTP + E Y +++ K N+ +
Sbjct: 222 LFPGTDHIDQLKLILRLVGTPGAELLKKISSESARNYIQSLTQMPKMNFANVF-----IG 276
Query: 348 LNETGXXXXXXXXXXDPYKRVTAMKAKKHPFFFEEPLPNAQ-LTLPNEECHESD---IKR 403
N D KR+TA +A H +F + P+ + + P ++ ES I
Sbjct: 277 ANPLAVDLLEKMLVLDSDKRITAAQALAHAYFAQYHDPDDEPVADPYDQSFESRDLLIDE 336
Query: 404 YKS-EMNESMSQRPP 417
+KS +E +S PP
Sbjct: 337 WKSLTYDEVISFVPP 351
>At3g61160 [G] KOG0658 Glycogen synthase kinase-3
Length = 431
Score = 126 bits (317), Expect = 9e-29
Identities = 97/348 (27%), Positives = 154/348 (43%), Gaps = 58/348 (16%)
Query: 54 NYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNHKN 113
+YR E +G G+FG VF+ L T KVAIK++L RE+ I++ ++H N
Sbjct: 101 SYRAEHVIGTGSFGVVFQAKCLETEEKVAIKKVLQDKRYK------NRELQIMRMLDHPN 154
Query: 114 IVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGLL 173
+V+L + T + D V Y + T + M L Y
Sbjct: 155 VVELKHSFFS---TTEKDELYLNLVLEYVPETIYRASRSYTKMNQHMPLIY--------- 202
Query: 174 HNPRVEFGMADVKNIMLQLLEGINYIH-CNKFLHRDIKTANILIDH-KGVVKIADFGLAR 231
++ Q+ +NY+H HRDIK N+L+++ VKI DFG A+
Sbjct: 203 -----------IQLYTYQICRAMNYLHQVVGVCHRDIKPQNLLVNNVTHEVKICDFGSAK 251
Query: 232 NYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFE 291
PN+ Y + +R+YRAPE++ G YT+A+D+W +GCV AE F
Sbjct: 252 MLIPGEPNISY-------------ICSRYYRAPELIFGATEYTSAIDMWSVGCVMAELFL 298
Query: 292 KKPILQGQTDIDQGHVIFKLMGTPSMDEWGLAYHLPGSELTKTNYK------STLQERFS 345
P+ G+T +DQ I K++GTP+ +E + ++K + F
Sbjct: 299 GHPLFPGETSVDQLVEIIKILGTPAREE------IKNMNPRYNDFKFPQIKAQPWHKIFR 352
Query: 346 KALNETGXXXXXXXXXXDPYKRVTAMKAKKHPFFFEEPLPNAQLTLPN 393
+ ++ P R TA++A HPFF + L + + +LPN
Sbjct: 353 RQVSPEAMDLASRLLQYSPNLRCTALEACAHPFF--DDLRDPRASLPN 398
>7290342 [G] KOG0658 Glycogen synthase kinase-3
Length = 1008
Score = 126 bits (317), Expect = 9e-29
Identities = 98/343 (28%), Positives = 151/343 (43%), Gaps = 47/343 (13%)
Query: 54 NYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNHKN 113
+Y + + +G G+FG VF+ T VAIK++L RE+ I++++ H N
Sbjct: 547 SYTDTKVIGNGSFGVVFQAKLCDTGELVAIKKVLQDRR------FKNRELQIMRKLEHCN 600
Query: 114 IVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGLL 173
IVKL+ Y S K D V Y +P V +
Sbjct: 601 IVKLLYFFY--SSGEKRDEVFLNLVLEY--------------------IPETVYKVARQY 638
Query: 174 HNPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHK-GVVKIADFGLARN 232
+ + ++ M QL + YIH HRDIK N+L+D + V+K+ DFG A+
Sbjct: 639 AKTKQTIPINFIRLYMYQLFRSLAYIHSLGICHRDIKPQNLLLDPETAVLKLCDFGSAKQ 698
Query: 233 YYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFEK 292
PN+ Y + +R+YRAPE++ G +YTT +D+W GCV AE
Sbjct: 699 LLHGEPNVSY-------------ICSRYYRAPELIFGAINYTTKIDVWSAGCVLAELLLG 745
Query: 293 KPILQGQTDIDQGHVIFKLMGTPSMDEWGLAYHLPG-SELTKTNYKSTLQERFSKALNET 351
+PI G + +DQ + K++GTP+ ++ + P +E KS ++ + T
Sbjct: 746 QPIFPGDSGVDQLVEVIKVLGTPTREQ--IREMNPNYTEFKFPQIKSHPWQKVFRIRTPT 803
Query: 352 -GXXXXXXXXXXDPYKRVTAMKAKKHPFFFEEPLPNAQLTLPN 393
P R+T +KA HP FF+E TLPN
Sbjct: 804 EAINLVSLLLEYTPSARITPLKACAHP-FFDELRMEGNHTLPN 845
>SPBPI064 [G] KOG0658 Glycogen synthase kinase-3
Length = 350
Score = 126 bits (316), Expect = 1e-28
Identities = 85/299 (28%), Positives = 130/299 (43%), Gaps = 42/299 (14%)
Query: 101 REITILKRMNHKNIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFM 160
RE+ I++ ++H NI+KLI + +P+ D T H +
Sbjct: 34 RELQIMRAISHPNIIKLIAFFHTHNPSK--DET-----------------------HLCL 68
Query: 161 ILPYM---VSDLTGLLHNPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILID 217
+L YM V D R +K QL + Y+H HRDIK N+L+D
Sbjct: 69 LLEYMPETVFDDMRWYTRRRKSIPNLSIKLYAFQLFRALAYLHSTGVCHRDIKPQNLLVD 128
Query: 218 HK-GVVKIADFGLARNYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTA 276
+K G++K+ DFG A+ S PN+ Y + +R+YRAPE+V G HYTT
Sbjct: 129 YKTGILKLCDFGSAKVLVPSEPNVSY-------------ICSRYYRAPELVFGATHYTTK 175
Query: 277 VDIWGIGCVFAEFFEKKPILQGQTDIDQGHVIFKLMGTPSMDEWGLAYHLPGSELTKTNY 336
+D+W CV AE F +P+ G + ++Q I +++GTPS E + +
Sbjct: 176 IDVWSAACVIAELFIGRPLFPGDSSVEQLVEIIRVLGTPSYHEISVMNPNYVNHSLPNVR 235
Query: 337 KSTLQERFSKALNETGXXXXXXXXXXDPYKRVTAMKAKKHPFFFEEPLPNAQLTLPNEE 395
TL+ + P KR++A++ HPFF E PN +E
Sbjct: 236 PHTLESVMPHNCTKNAMDLLHKMLTYVPSKRISAIEVLTHPFFDELRDPNCMYHCSRDE 294
>YPR054w [T] KOG0660 Mitogen-activated protein kinase
Length = 388
Score = 125 bits (315), Expect = 2e-28
Identities = 107/357 (29%), Positives = 166/357 (45%), Gaps = 54/357 (15%)
Query: 61 LGQGTFGEV----FKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMN----HK 112
LG+G +G V FKG ++A+K+I K+ I +R I LK MN HK
Sbjct: 44 LGKGAYGTVCSVKFKG--RSPAARIAVKKISNIFNKE---ILLKRAIRELKFMNFFKGHK 98
Query: 113 NIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGL 172
NIV LI++ + ++SP Y G + ++ Y DL +
Sbjct: 99 NIVNLIDL--------EIVTSSP-----YDGLYCYQE-----------LIDY---DLAKV 131
Query: 173 LHNPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLARN 232
+H+ V+ +K + Q+L G+ YIH +HRD+K NIL G +KI DFGLAR
Sbjct: 132 IHSS-VQLSEFHIKYFLYQILCGLKYIHSADVIHRDLKPGNILCTLNGCLKICDFGLARG 190
Query: 233 YYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFEK 292
+ + + T+ V TRWYRAPE++L ++ Y+ +VDIW +GC+ AEF+ +
Sbjct: 191 IHAG----FFKCHSTVQPHITNYVATRWYRAPELLLSNQPYSKSVDIWAVGCILAEFYAR 246
Query: 293 KPILQGQTDIDQGHVIFKLMGTPSMD---EWGL--AYHLPGSELTKTNYKSTLQERFSKA 347
KP+ G+ + Q I K++GTP D ++G A++L G YK
Sbjct: 247 KPVFMGRDSMHQIFEIIKVLGTPDKDILIKFGTIKAWNL-GKNSNNPVYKKIPWSNIFPF 305
Query: 348 LNETGXXXXXXXXXXDPYKRVTAMKAKKHPFFFEEPLPNAQ---LTLPNEECHESDI 401
+ D R+ +A HPF E P+ + L P + +ES++
Sbjct: 306 ASHEAINLIESLLHWDSTHRLNVEQAISHPFLNEVRKPDDEPVCLQGPFDFTYESEL 362
>At1g07880 [T] KOG0660 Mitogen-activated protein kinase
Length = 363
Score = 125 bits (315), Expect = 2e-28
Identities = 96/357 (26%), Positives = 159/357 (43%), Gaps = 56/357 (15%)
Query: 59 EKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNHKNIVKLI 118
E +G+G +G V + TN +VAIK+I + + REI +L M+H N++K+
Sbjct: 37 EPIGRGAYGIVCCATNSETNEEVAIKKIANAFDNRVDAKRTLREIKLLSHMDHDNVIKIK 96
Query: 119 EIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGLLHNPRV 178
+I+ E P + + +++ M +DL ++ + +
Sbjct: 97 DII--ELPEKERF------------------------EDVYIVYELMDTDLHQIIRSTQT 130
Query: 179 EFGMAD--VKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLARNYYGS 236
+ D + + Q+L G+ YIH LHRD+K +N++++ +KI DFGLAR
Sbjct: 131 ---LTDDHCQYFLYQILRGLKYIHSANVLHRDLKPSNLVLNTNCDLKICDFGLART---- 183
Query: 237 PPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFEKKPIL 296
+ T VVTRWYRAPE++L YT A+DIW +GC+F E ++ +
Sbjct: 184 ---------SNETEIMTEYVVTRWYRAPELLLNSSEYTGAIDIWSVGCIFMEILRRETLF 234
Query: 297 QGQTDIDQGHVIFKLMGTPSMDEWGLAYHLPGSELTKT---NYKSTLQERFSKALNETGX 353
G+ + Q +I +L+G+P + + K K + +E+F ++
Sbjct: 235 PGKDYVQQLKLITELLGSPDDSDLDFLRSDNARKYVKQLPHVQKQSFREKFPN-ISPMAL 293
Query: 354 XXXXXXXXXDPYKRVTAMKAKKHPFFF------EEPLPNAQLTLPNEE--CHESDIK 402
DP KR+T +A K P+ EEP + EE E DIK
Sbjct: 294 DLAEKMLVFDPSKRITVDEALKQPYLASLHEINEEPTCPTPFSFDFEETALDEQDIK 350
>SPAC23H4.17c [K] KOG0666 Cyclin C-dependent kinase CDK8
Length = 352
Score = 125 bits (314), Expect = 2e-28
Identities = 97/356 (27%), Positives = 158/356 (44%), Gaps = 74/356 (20%)
Query: 61 LGQGTFGEVFKGIHLGTNRK---------VAIKRILVRAEKDLFPITAQREITILKRMNH 111
+ GT+G+V+K + +N K K++ A++ +A RE+ + + + H
Sbjct: 11 ISSGTYGKVYKAVSSNSNDKRLFAIKKFKAESKQVSSNAQQTGVSQSAIREMMLCREIQH 70
Query: 112 KNIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTG 171
+NIV L++++ + M+ Y DL
Sbjct: 71 ENIVSLVQVLLKDGTIS-------------------------------MVFEYAEHDLLQ 99
Query: 172 LLH----NPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADF 227
++H + + + +K+I+ Q++ G+ Y+H N +HRD+K ANI+I G VKI D
Sbjct: 100 IIHFHSRSRTRQIPPSILKSILWQIINGVAYLHENWIMHRDLKPANIMITATGKVKIGDL 159
Query: 228 GLARNYYGSPPNLKYPGGAGSGAKYTS--VVVTRWYRAPEIVLGDRHYTTAVDIWGIGCV 285
GL R P L + Y+S VVVT WYRAPE++LG YT A+D+W IGC+
Sbjct: 160 GLGRLI--RDPILPF---------YSSDRVVVTIWYRAPELLLGAHDYTPAIDVWAIGCI 208
Query: 286 FAEFFEKKPILQG-QTDIDQGHV----------IFKLMGTPSMDEW-GLA-----YHLPG 328
+ E P+ +G + ++ V I +L+GTP+ + W GL Y L
Sbjct: 209 YGEMLALSPLFKGDEIKMEDKKVVPFQSTQMLRIMELLGTPTEERWPGLKNYPEYYQLSS 268
Query: 329 SELTKTNYKSTLQERFSKALNETGXXXXXXXXXXDPYKRVTAMKAKKHPFFFEEPL 384
E+ N + K + G DP R+TA +A +H FF + L
Sbjct: 269 FEVRYWNNLLPQWYQTVKNRDPQGLDLLMKMLQYDPKSRITAKQALEHVFFTSDKL 324
>YMR139w [G] KOG0658 Glycogen synthase kinase-3
Length = 370
Score = 125 bits (313), Expect = 3e-28
Identities = 106/387 (27%), Positives = 168/387 (43%), Gaps = 66/387 (17%)
Query: 59 EKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNHKNIVKLI 118
E +G G+FG VF + TN KVAIK++L RE+ I+K ++H NI+ L
Sbjct: 43 EVVGHGSFGVVFATVIQETNEKVAIKKVLQDKR------FKNRELEIMKMLSHINIIDLK 96
Query: 119 EIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGLLHN--- 175
Y+ +Q ++ + +IL YM L L +
Sbjct: 97 YFFYERD----------------------SQDEI----YLNLILEYMPQSLYQRLRHFVH 130
Query: 176 PRVEFGMADVKNIMLQLLEGINYIH-CNKFLHRDIKTANILIDHKG-VVKIADFGLARNY 233
R ++K M QL + +NY+H HRDIK N+L+D + +K+ DFG A+
Sbjct: 131 QRTPMSRLEIKYYMFQLFKSLNYLHHFANVCHRDIKPQNLLVDPETWSLKLCDFGSAKQL 190
Query: 234 YGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFEKK 293
+ PN+ Y + +R+YRAPE++ G +YT +DIW GCV AE +
Sbjct: 191 KPTEPNVSY-------------ICSRYYRAPELIFGATNYTNQIDIWSSGCVMAELLLGQ 237
Query: 294 PILQGQTDIDQGHVIFKLMGTPSMDEWGLAYHLPGSELTKTNYKSTLQERFSKALNETGX 353
P+ G++ IDQ I K++GTPS E + + E K R K ++
Sbjct: 238 PMFPGESGIDQLVEIIKILGTPSKQEI-CSMNPNYMEHKFPQIKPIPLSRVFKKEDDQTV 296
Query: 354 XXXXXXXXXDPYKRVTAMKAKKHPFFFEEPLPNAQLTLPNEECHESDIKRYKSEMNESMS 413
DP +R A++ P+F E L + ++ +D+K + + N +
Sbjct: 297 EFLADVLKYDPLERFNALQCLCSPYFDELKLDDGKINQIT-----TDLKLLEFDENVEL- 350
Query: 414 QRPPSAPTGHTSTDNSIRAVTGAAFPK 440
GH S D + +V +PK
Sbjct: 351 --------GHLSPD-ELSSVKKKLYPK 368
>Hs20986531 [T] KOG0660 Mitogen-activated protein kinase
Length = 360
Score = 124 bits (312), Expect = 3e-28
Identities = 94/331 (28%), Positives = 148/331 (44%), Gaps = 50/331 (15%)
Query: 55 YREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNHKNI 114
Y +G+G +G V +VAIK+I E + REI IL R H+NI
Sbjct: 25 YTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKISP-FEHQTYCQRTLREIKILLRFRHENI 83
Query: 115 VKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGLLH 174
+ + +I+ +PT + K +++ M +DL LL
Sbjct: 84 IGINDII--RAPT------------------------IEQMKDVYIVQDLMETDLYKLLK 117
Query: 175 NPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLARNYY 234
+ + + Q+L G+ YIH LHRD+K +N+L++ +KI DFGLAR
Sbjct: 118 TQHL--SNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLAR--- 172
Query: 235 GSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFEKKP 294
+ P+ + G T V TRWYRAPEI+L + YT ++DIW +GC+ AE +P
Sbjct: 173 VADPDHDHTG------FLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRP 226
Query: 295 ILQGQTDIDQGHVIFKLMGTPSMDEWGLAYHLPGSEL-------TKTNYKSTLQERFSKA 347
I G+ +DQ + I ++G+PS ++ +L K + SKA
Sbjct: 227 IFPGKHYLDQLNHILGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNADSKA 286
Query: 348 LNETGXXXXXXXXXXDPYKRVTAMKAKKHPF 378
L+ +P+KR+ +A HP+
Sbjct: 287 LD-----LLDKMLTFNPHKRIEVEQALAHPY 312
>Hs20986529 [T] KOG0660 Mitogen-activated protein kinase
Length = 360
Score = 124 bits (310), Expect = 6e-28
Identities = 94/331 (28%), Positives = 147/331 (44%), Gaps = 50/331 (15%)
Query: 55 YREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNHKNI 114
Y +G+G +G V +VAIK+I E + REI IL R H+NI
Sbjct: 25 YTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKISP-FEHQTYCQRTLREIKILLRFRHENI 83
Query: 115 VKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGLLH 174
+ + +I+ +PT + K +++ M +DL LL
Sbjct: 84 IGINDII--RAPT------------------------IEQMKDVYIVQDLMETDLYKLLK 117
Query: 175 NPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLARNYY 234
+ + + Q+L G+ YIH LHRD+K +N+L++ +KI DFGLAR
Sbjct: 118 TQHL--SNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLAR--- 172
Query: 235 GSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFEKKP 294
+ P+ + G T V TRWYRAPEI+L + YT ++DIW +GC+ AE +P
Sbjct: 173 VADPDHDHTG------FLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRP 226
Query: 295 ILQGQTDIDQGHVIFKLMGTPSMDEWGLAYHLPGSEL-------TKTNYKSTLQERFSKA 347
I G+ +DQ I ++G+PS ++ +L K + SKA
Sbjct: 227 IFPGKHYLDQLKHILGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNADSKA 286
Query: 348 LNETGXXXXXXXXXXDPYKRVTAMKAKKHPF 378
L+ +P+KR+ +A HP+
Sbjct: 287 LD-----LLDKMLTFNPHKRIEVEQALAHPY 312
>At1g53510 [T] KOG0660 Mitogen-activated protein kinase
Length = 603
Score = 123 bits (309), Expect = 8e-28
Identities = 95/331 (28%), Positives = 148/331 (44%), Gaps = 41/331 (12%)
Query: 53 NNYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNHK 112
N YR E +G+G++G V I T KVAIK+I E + RE+ +L+ + H
Sbjct: 11 NRYRILEVIGKGSYGVVCAAIDTHTGEKVAIKKINDVFEHISDALRILREVKLLRLLRHP 70
Query: 113 NIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGL 172
+IV++ I+ P K + K +++ M SDL +
Sbjct: 71 DIVEIKSIML---PPSKREF-----------------------KDIYVVFELMESDLHQV 104
Query: 173 LHNPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLARN 232
+ + + + Q+L + ++H HRD+K NIL + +K+ DFGLAR
Sbjct: 105 I-KANDDLTREHHQFFLYQMLRALKFMHTANVYHRDLKPKNILANANCKLKVCDFGLARV 163
Query: 233 YYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGD-RHYTTAVDIWGIGCVFAEFFE 291
+ P + +T V TRWYRAPE+ YT A+D+W IGC+FAE
Sbjct: 164 AFNDTPTTVF---------WTDYVATRWYRAPELCGSFFSKYTPAIDVWSIGCIFAEVLT 214
Query: 292 KKPILQGQTDIDQGHVIFKLMGTPSMDE-WGLAYHLPGSELTKTNYKS--TLQERFSKAL 348
KP+ G++ + Q +I L+GTP + G+ LT+ K+ T ++FSKA
Sbjct: 215 GKPLFPGKSVVHQLELITDLLGTPKSETISGVRNDKARKYLTEMRKKNPVTFSQKFSKA- 273
Query: 349 NETGXXXXXXXXXXDPYKRVTAMKAKKHPFF 379
+ DP R T +A P+F
Sbjct: 274 DPLALRLLQRLLAFDPKDRPTPAEALADPYF 304
>Hs4503069 [T] KOG0660 Mitogen-activated protein kinase
Length = 360
Score = 122 bits (307), Expect = 1e-27
Identities = 97/373 (26%), Positives = 162/373 (43%), Gaps = 55/373 (14%)
Query: 55 YREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNHKNI 114
Y+ +G G +G V T +VA+K++ + + RE+ +LK M H+N+
Sbjct: 24 YQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENV 83
Query: 115 VKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGLLH 174
+ L+++ T R + ++ +++ M +DL ++
Sbjct: 84 IGLLDVF-----------TPARSLEEFND--------------VYLVTHLMGADLNNIVK 118
Query: 175 NPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLARNYY 234
++ V+ ++ Q+L G+ YIH +HRD+K +N+ ++ +KI DFGLAR+
Sbjct: 119 CQKLTDD--HVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARH-- 174
Query: 235 GSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFEKKP 294
+ + T V TRWYRAPEI+L HY VDIW +GC+ AE +
Sbjct: 175 -------------TDDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRT 221
Query: 295 ILQGQTDIDQGHVIFKLMGTPSMDEWGLAYHLPGSELTKTNYKSTLQERFSKA-----LN 349
+ G I+Q I +L GTP L +P E T + + A N
Sbjct: 222 LFPGTDHINQLQQIMRLTGTPPA---YLINRMPSHEARNYIQSLTQMPKMNFANVFIGAN 278
Query: 350 ETGXXXXXXXXXXDPYKRVTAMKAKKHPFFFEEPLPNAQ-LTLPNEECHESD---IKRYK 405
D KR+TA +A H +F + P+ + + P ++ ES I +K
Sbjct: 279 PLAVDLLEKMLVLDSDKRITAAQALAHAYFAQYHDPDDEPVADPYDQSFESRDLLIDEWK 338
Query: 406 S-EMNESMSQRPP 417
S +E +S PP
Sbjct: 339 SLTYDEVISFVPP 351
>CE06686 [T] KOG0660 Mitogen-activated protein kinase
Length = 377
Score = 122 bits (307), Expect = 1e-27
Identities = 101/372 (27%), Positives = 163/372 (43%), Gaps = 58/372 (15%)
Query: 53 NNYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNHK 112
N Y +G G +G V + +VAIK+ + + RE+ +L+ M H+
Sbjct: 33 NYYINLTPIGTGAYGTVCAAECTRSGTRVAIKKFNRPFQSIIHARRTYRELRLLRCMCHE 92
Query: 113 NIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGL 172
NI+ L+++ TP N N I +F +L M +DL+ +
Sbjct: 93 NIIDLLDVF-----TP---------------NENVND---IEDVYFVSML--MGADLSNI 127
Query: 173 LHNPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLARN 232
L R+ ++ ++ Q+L G+ YIH +HRD+K +NI ++ +KI DFGLAR
Sbjct: 128 LKIQRLNDD--HIQFLVYQILRGLKYIHSADIIHRDLKPSNIAVNEDCELKILDFGLARQ 185
Query: 233 YYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFEK 292
+ ++ T V TRWYRAPEI+L HYT VD+W +GC+ AE
Sbjct: 186 ---------------TDSEMTGYVATRWYRAPEIMLNWMHYTQTVDVWSVGCILAELITG 230
Query: 293 KPILQGQTDIDQGHVIFKLMGTPSMD-------EWGLAYHLPGSELTKTNYKSTLQERFS 345
K + G IDQ I + GTP + E Y ++T+ ++K +
Sbjct: 231 KTLFPGSDHIDQLTRIMSVTGTPDEEFLKKISSEEARNYIRNLPKMTRRDFKRLFAQATP 290
Query: 346 KALNETGXXXXXXXXXXDPYKRVTAMKAKKHPFFF----EEPLPNAQLTLPNEECHESDI 401
+A++ DP +R TA +A +H + E P A+ N++ I
Sbjct: 291 QAID-----LLEKMLHLDPDRRPTAKEAMEHEYLAAYHDETDEPIAEEMDLNDDVRADTI 345
Query: 402 KRYKSEMNESMS 413
+K + E +S
Sbjct: 346 DEWKKIIWEEIS 357
>Hs20986516 [T] KOG0660 Mitogen-activated protein kinase
Length = 307
Score = 122 bits (306), Expect = 2e-27
Identities = 73/264 (27%), Positives = 125/264 (46%), Gaps = 42/264 (15%)
Query: 55 YREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNHKNI 114
Y+ +G G +G V T +VA+K++ + + RE+ +LK M H+N+
Sbjct: 24 YQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENV 83
Query: 115 VKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGLLH 174
+ L+++ T R + ++ +++ M +DL ++
Sbjct: 84 IGLLDVF-----------TPARSLEEFND--------------VYLVTHLMGADLNNIVK 118
Query: 175 NPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLARNYY 234
++ V+ ++ Q+L G+ YIH +HRD+K +N+ ++ +KI DFGLAR+
Sbjct: 119 CQKLTDD--HVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARH-- 174
Query: 235 GSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFEKKP 294
+ + T V TRWYRAPEI+L HY VDIW +GC+ AE +
Sbjct: 175 -------------TDDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRT 221
Query: 295 ILQGQTDIDQGHVIFKLMGTPSMD 318
+ G IDQ +I +L+GTP +
Sbjct: 222 LFPGTDHIDQLKLILRLVGTPGAE 245
>Hs20986514 [T] KOG0660 Mitogen-activated protein kinase
Length = 297
Score = 122 bits (306), Expect = 2e-27
Identities = 73/264 (27%), Positives = 125/264 (46%), Gaps = 42/264 (15%)
Query: 55 YREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNHKNI 114
Y+ +G G +G V T +VA+K++ + + RE+ +LK M H+N+
Sbjct: 24 YQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENV 83
Query: 115 VKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGLLH 174
+ L+++ T R + ++ +++ M +DL ++
Sbjct: 84 IGLLDVF-----------TPARSLEEFND--------------VYLVTHLMGADLNNIVK 118
Query: 175 NPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLARNYY 234
++ V+ ++ Q+L G+ YIH +HRD+K +N+ ++ +KI DFGLAR+
Sbjct: 119 CQKLTDD--HVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARH-- 174
Query: 235 GSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFEKKP 294
+ + T V TRWYRAPEI+L HY VDIW +GC+ AE +
Sbjct: 175 -------------TDDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRT 221
Query: 295 ILQGQTDIDQGHVIFKLMGTPSMD 318
+ G IDQ +I +L+GTP +
Sbjct: 222 LFPGTDHIDQLKLILRLVGTPGAE 245
>SPAC24B11.06c [T] KOG0660 Mitogen-activated protein kinase
Length = 349
Score = 122 bits (305), Expect = 2e-27
Identities = 94/333 (28%), Positives = 146/333 (43%), Gaps = 63/333 (18%)
Query: 55 YREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNHKNI 114
Y + + +G G FG V T VA+K+I+ + RE+ +LK + H+NI
Sbjct: 20 YSDLQPIGMGAFGLVCSAKDQLTGMNVAVKKIMKPFSTPVLAKRTYRELKLLKHLRHENI 79
Query: 115 VKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGLLH 174
+ L +I +P D + + + +DL LL
Sbjct: 80 ISLSDIFI----SPFED--------------------------IYFVTELLGTDLHRLLT 109
Query: 175 NPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLARNYY 234
+ +E ++ + Q+L G+ ++H +HRD+K +NILI+ +KI DFGLAR
Sbjct: 110 SRPLETQF--IQYFLYQILRGLKFVHSAGVIHRDLKPSNILINENCDLKICDFGLAR--- 164
Query: 235 GSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFEKKP 294
++ P + T V TR+YRAPEI+L + Y VDIW GC+FAE E KP
Sbjct: 165 -----IQDP-------QMTGYVSTRYYRAPEIMLTWQKYNVEVDIWSAGCIFAEMIEGKP 212
Query: 295 ILQGQTDIDQGHVIFKLMGTPSMD---------EWGLAYHLPGSELTKTNYKSTLQERFS 345
+ G+ ++Q +I +L+GTP M+ LP E K E+F
Sbjct: 213 LFPGRDHVNQFSIITELLGTPPMEVIETICSKNTLRFVQSLPQKE------KVPFAEKFK 266
Query: 346 KALNETGXXXXXXXXXXDPYKRVTAMKAKKHPF 378
A + DP KR++A A H +
Sbjct: 267 NA-DPDAIDLLEKMLVFDPRKRISAADALAHNY 298
>At4g11330 [T] KOG0660 Mitogen-activated protein kinase
Length = 373
Score = 122 bits (305), Expect = 2e-27
Identities = 83/305 (27%), Positives = 141/305 (46%), Gaps = 44/305 (14%)
Query: 77 TNRKVAIKRILVRAEKDLFPITAQREITILKRMNHKNIVKLIEIVYDESPTPKTDSTSPR 136
T+ ++AIK+I + + REI +L+ + H+N+V + +I+ P K D
Sbjct: 62 THEEIAIKKIGKAFDNKVDAKRTLREIKLLRHLEHENVVVIKDII---RPPKKEDFVD-- 116
Query: 137 PVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGLLHNPRVEFGMADVKNIMLQLLEGI 196
+++ M +DL ++ + + + + Q+L G+
Sbjct: 117 ---------------------VYIVFELMDTDLHQIIRSNQ-SLNDDHCQYFLYQILRGL 154
Query: 197 NYIHCNKFLHRDIKTANILIDHKGVVKIADFGLARNYYGSPPNLKYPGGAGSGAKY-TSV 255
YIH LHRD+K +N+L++ +KI DFGLAR S +Y T
Sbjct: 155 KYIHSANVLHRDLKPSNLLLNSNCDLKITDFGLARTT--------------SETEYMTEY 200
Query: 256 VVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFEKKPILQGQTDIDQGHVIFKLMGTP 315
VVTRWYRAPE++L YT+A+D+W +GC+FAE ++P+ G+ + Q +I +L+G+P
Sbjct: 201 VVTRWYRAPELLLNSSEYTSAIDVWSVGCIFAEIMTREPLFPGKDYVHQLKLITELIGSP 260
Query: 316 SMDEWGLAYHLPGSELTKTNYKSTLQERFSK--ALNETGXXXXXXXXXXDPYKRVTAMKA 373
+ K K Q ++ ++N T DP KR+T +A
Sbjct: 261 DGASLEFLRSANARKYVKELPKFPRQNFSARFPSMNSTAIDLLEKMLVFDPVKRITVEEA 320
Query: 374 KKHPF 378
+P+
Sbjct: 321 LCYPY 325
>At2g46070 [T] KOG0660 Mitogen-activated protein kinase
Length = 406
Score = 122 bits (305), Expect = 2e-27
Identities = 95/353 (26%), Positives = 156/353 (43%), Gaps = 52/353 (14%)
Query: 61 LGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNHKNIVKLIEI 120
+G+G G V ++ T KVAIK+I + + REI +L+ M+H+N++ + +I
Sbjct: 81 IGRGACGIVCAAVNSVTGEKVAIKKIGNAFDNIIDAKRTLREIKLLRHMDHENVITIKDI 140
Query: 121 VYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGLLHNPRVEF 180
V RP N+ +++ M +DL +L + +
Sbjct: 141 V--------------RPPQRDIFNDV------------YIVYELMDTDLQRILRSNQT-L 173
Query: 181 GMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLARNYYGSPPNL 240
+ ++ QLL G+ Y+H LHRD++ +N+L++ K +KI DFGLAR +
Sbjct: 174 TSDQCRFLVYQLLRGLKYVHSANILHRDLRPSNVLLNSKNELKIGDFGLARTTSDTDFMT 233
Query: 241 KYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFEKKPILQGQT 300
+Y VVTRWYRAPE++L YT A+DIW +GC+ E +P+ G+
Sbjct: 234 EY-------------VVTRWYRAPELLLNCSEYTAAIDIWSVGCILGEIMTGQPLFPGKD 280
Query: 301 DIDQGHVIFKLMGTPSMDEWGLAYHLPGSELTK--TNY-KSTLQERFSKALNETGXXXXX 357
+ Q +I +L+G+P G + Y K RF K + T
Sbjct: 281 YVHQLRLITELVGSPDNSSLGFLRSDNARRYVRQLPRYPKQQFAARFPK-MPTTAIDLLE 339
Query: 358 XXXXXDPYKRVTAMKAKKHPFF------FEEPLPNAQLTLPNE--ECHESDIK 402
DP +R++ +A H + +EP+ + + E C E IK
Sbjct: 340 RMLVFDPNRRISVDEALGHAYLSPHHDVAKEPVCSTPFSFDFEHPSCTEEHIK 392
>At2g42880 [T] KOG0660 Mitogen-activated protein kinase
Length = 594
Score = 122 bits (305), Expect = 2e-27
Identities = 122/463 (26%), Positives = 183/463 (39%), Gaps = 78/463 (16%)
Query: 53 NNYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNHK 112
N ++ +E +G+G++G V I T KVAIK+I E REI +L+ + H
Sbjct: 11 NRFKVQEVIGKGSYGVVCSAIDTLTGEKVAIKKIHDIFEHISDAARILREIKLLRLLRHP 70
Query: 113 NIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGL 172
+IV++ I+ S D +++ M SDL +
Sbjct: 71 DIVEIKHIMLPPSRREFKD--------------------------IYVVFELMESDLHQV 104
Query: 173 LHNPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLARN 232
+ + + + QLL + YIH HRD+K NIL + +KI DFGLAR
Sbjct: 105 I-KANDDLTREHYQFFLYQLLRALKYIHTANVYHRDLKPKNILANANCKLKICDFGLARV 163
Query: 233 YYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRH--YTTAVDIWGIGCVFAEFF 290
+ P + +T V TRWYRAPE+ G + YT A+DIW IGC+FAE
Sbjct: 164 AFNDTPTTIF---------WTDYVATRWYRAPELC-GSFYSKYTPAIDIWSIGCIFAEVL 213
Query: 291 EKKPILQGQTDIDQGHVIFKLMGTPSMDEWGLAYHLPGSE-LTKTNYKSTL--QERFSKA 347
KP+ G+ + Q ++ L+GTPS+D + LT K + ++F A
Sbjct: 214 MGKPLFPGKNVVHQLDLMTDLLGTPSLDTISRVRNEKARRYLTSMRKKPPIPFAQKFPNA 273
Query: 348 LNETGXXXXXXXXXXDPYKRVTAMKAKKHPFFFE----------EPLPNAQLTLPNEECH 397
+ DP R TA +A P+F +P+ + +
Sbjct: 274 -DPLSLKLLERLLAFDPKDRPTAEEALADPYFKGLAKVEREPSCQPITKMEFEFERRKVT 332
Query: 398 ESDIK--------RYKSEMNESMSQRPPSAPTGHTSTDNSIR----------AVTGAAFP 439
+ DI+ Y ++ + A + S + R TG P
Sbjct: 333 KEDIRELISREILEYHPQLLKDHMNGADKASFLYPSAVDQFRRQFAHLEENSGKTGPVAP 392
Query: 440 KEASIPKAPRPEHIKSTIPA---QP----SASRYNGAATQNIP 475
E PR I ST A QP + + N TQNIP
Sbjct: 393 LERKHASLPRSTVIHSTAVARGGQPKLMNNTNTLNPETTQNIP 435
>At4g18710 [G] KOG0658 Glycogen synthase kinase-3
Length = 380
Score = 121 bits (304), Expect = 3e-27
Identities = 101/352 (28%), Positives = 156/352 (43%), Gaps = 58/352 (16%)
Query: 47 GVTKFLNNYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILV-RAEKDLFPITAQREITI 105
G K +Y E +G G+FG VF+ L T VAIK++L R K+ RE+ +
Sbjct: 32 GEPKQTISYMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKN-------RELQL 84
Query: 106 LKRMNHKNIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYM 165
++ M+H N+V L + +T ++ +L +++ Y+
Sbjct: 85 MRVMDHPNVVCLKHCFF----------------------STTSKDELFLN----LVMEYV 118
Query: 166 VSDLTGLL---HNPRVEFGMADVKNIMLQLLEGINYIH-CNKFLHRDIKTANILID---H 218
L +L + + VK M Q+ G+ YIH HRD+K N+L+D H
Sbjct: 119 PESLYRVLKHYSSANQRMPLVYVKLYMYQIFRGLAYIHNVAGVCHRDLKPQNLLVDPLTH 178
Query: 219 KGVVKIADFGLARNYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVD 278
+ VKI DFG A+ N+ Y + +R+YRAPE++ G YTT++D
Sbjct: 179 Q--VKICDFGSAKQLVKGEANISY-------------ICSRFYRAPELIFGATEYTTSID 223
Query: 279 IWGIGCVFAEFFEKKPILQGQTDIDQGHVIFKLMGTPSMDEWG-LAYHLPGSELTKTNYK 337
IW GCV AE +P+ G+ +DQ I K++GTP+ +E + H +
Sbjct: 224 IWSAGCVLAELLLGQPLFPGENAVDQLVEIIKVLGTPTREEIRCMNPHYTDFRFPQIK-A 282
Query: 338 STLQERFSKALNETGXXXXXXXXXXDPYKRVTAMKAKKHPFFFEEPLPNAQL 389
+ F K + P R TA++A HPFF E PNA+L
Sbjct: 283 HPWHKIFHKRMPPEAIDFASRLLQYSPSLRCTALEACAHPFFDELREPNARL 334
>At3g05840 [G] KOG0658 Glycogen synthase kinase-3
Length = 409
Score = 121 bits (303), Expect = 4e-27
Identities = 99/352 (28%), Positives = 150/352 (42%), Gaps = 58/352 (16%)
Query: 47 GVTKFLNNYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILV-RAEKDLFPITAQREITI 105
G K +Y E +G G+FG VF+ L T VAIK++L R K+ RE+
Sbjct: 65 GQPKQTISYMAERVVGHGSFGVVFQAKCLETGETVAIKKVLQDRRYKN-------RELQT 117
Query: 106 LKRMNHKNIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYM 165
++ ++H N+V L + T + D V Y +P
Sbjct: 118 MRLLDHPNVVSLKHCFFS---TTEKDELYLNLVLEY--------------------VPET 154
Query: 166 VSDLTGLLHNPRVEFGMADVKNIMLQLLEGINYIH-CNKFLHRDIKTANILID-HKGVVK 223
V + + + VK Q+ ++YIH C HRDIK N+L++ H VK
Sbjct: 155 VHRVIKHYNKLNQRMPLVYVKLYTYQIFRSLSYIHRCIGVCHRDIKPQNLLVNPHTHQVK 214
Query: 224 IADFGLARNYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIG 283
+ DFG A+ PN+ Y + +R+YRAPE++ G YTTA+D+W G
Sbjct: 215 LCDFGSAKVLVKGEPNISY-------------ICSRYYRAPELIFGATEYTTAIDVWSAG 261
Query: 284 CVFAEFFEKKPILQGQTDIDQGHVIFKLMGTPSMDEWGLAYHLPGSELTKTNYK------ 337
CV AE +P+ G++ +DQ I K++GTP+ +E + T +K
Sbjct: 262 CVLAELLLGQPLFPGESGVDQLVEIIKVLGTPTREE------IKCMNPNYTEFKFPQIKA 315
Query: 338 STLQERFSKALNETGXXXXXXXXXXDPYKRVTAMKAKKHPFFFEEPLPNAQL 389
+ F K + P R A+ + HPFF E PNA+L
Sbjct: 316 HPWHKIFHKRMPPEAVDLVSRLLQYSPNLRCAALDSLVHPFFDELRDPNARL 367
>At1g57870 [G] KOG0658 Glycogen synthase kinase-3
Length = 420
Score = 121 bits (303), Expect = 4e-27
Identities = 99/344 (28%), Positives = 147/344 (41%), Gaps = 56/344 (16%)
Query: 54 NYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNHKN 113
+Y E +G G+FG VF+ T VAIK++L RE+ I++ ++H N
Sbjct: 81 SYIAEHVVGTGSFGMVFQAKCRETGEVVAIKKVLQDKRYK------NRELQIMQMLDHPN 134
Query: 114 IVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGLL 173
+V L Y + + N TA ++ L L+
Sbjct: 135 VVCLKHSFYSRTENEEVYLNLVLEFVPETVNRTARSYS-------------RMNQLMPLI 181
Query: 174 HNPRVEFGMADVKNIMLQLLEGINYIH-CNKFLHRDIKTANILID-HKGVVKIADFGLAR 231
+ VK Q+ G+ Y+H C HRDIK N+L++ H +KI DFG A+
Sbjct: 182 Y----------VKLYTYQICRGLAYLHNCCGLCHRDIKPQNLLVNPHTHQLKICDFGSAK 231
Query: 232 NYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFE 291
PN+ Y + +R+YRAPE++ G YTTA+DIW GCV AE
Sbjct: 232 VLVKGEPNISY-------------ICSRYYRAPELIFGATEYTTAIDIWSTGCVMAELLL 278
Query: 292 KKPILQGQTDIDQGHVIFKLMGTPSMDEWGLAYHLPGSELTKTNYK------STLQERFS 345
+P+ G++ +DQ I K++GTP+ +E + T +K + F
Sbjct: 279 GQPLFPGESGVDQLVEIIKVLGTPTREE------IKCMNPNYTEFKFPQIKPHPWHKVFQ 332
Query: 346 KALNETGXXXXXXXXXXDPYKRVTAMKAKKHPFFFEEPLPNAQL 389
K L P R TA++A HPFF E PNA+L
Sbjct: 333 KRLPPEAVDLLCRFFQYSPNLRCTAVEACIHPFFDELRDPNARL 376
>Hs21237745 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 424
Score = 120 bits (302), Expect = 5e-27
Identities = 110/444 (24%), Positives = 182/444 (40%), Gaps = 78/444 (17%)
Query: 25 VKDDKTGLEYIQVQSRENEKVYGVTKFLNNYREEEKLGQGTFGEVFKGIHLGTNRKVAIK 84
+ D K ++ VQ ++ L Y++ + +G G G V VA+K
Sbjct: 1 MSDSKCDSQFYSVQVADS-----TFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVK 55
Query: 85 RILVRAEKDLFPITAQREITILKRMNHKNIVKLIEIVYDESPTPKTDSTSPRPVGNYHGN 144
++ + A RE+ +LK +NHKNI+ L+ + TP
Sbjct: 56 KLSRPFQNQTHAKRAYRELVLLKCVNHKNIISLLNVF-----TP---------------- 94
Query: 145 NTANQQKLITGKHFFMILPYMVSDLTGLLHNPRVEFGMADVKNIMLQLLEGINYIHCNKF 204
Q+ L + ++++ M ++L ++H +E + ++ Q+L GI ++H
Sbjct: 95 ----QKTLEEFQDVYLVMELMDANLCQVIH---MELDHERMSYLLYQMLCGIKHLHSAGI 147
Query: 205 LHRDIKTANILIDHKGVVKIADFGLARNYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAP 264
+HRD+K +NI++ +KI DFGLAR A + T VVTR+YRAP
Sbjct: 148 IHRDLKPSNIVVKSDCTLKILDFGLART-------------ACTNFMMTPYVVTRYYRAP 194
Query: 265 EIVLGDRHYTTAVDIWGIGCVFAEFFEKKPILQGQTDIDQGHVIFKLMGTPSMDEWGLAY 324
E++LG Y VDIW +GC+ AE K + G+ IDQ + + + +GTPS A
Sbjct: 195 EVILG-MGYKENVDIWSVGCIMAEMVLHKVLFPGRDYIDQWNKVIEQLGTPS------AE 247
Query: 325 HLPGSELTKTNYKST--------LQERF-----------SKALNETGXXXXXXXXXXDPY 365
+ + T NY +E F K DP
Sbjct: 248 FMKKLQPTVRNYVENRPKYPGIKFEELFPDWIFPSESERDKIKTSQARDLLSKMLVIDPD 307
Query: 366 KRVTAMKAKKHPFF------FEEPLPNAQLTLPNEECHESDIKRYKSEMNESMSQRPPSA 419
KR++ +A +HP+ E P Q+ E E I+ +K + + + +
Sbjct: 308 KRISVDEALRHPYITVWYDPAEAEAPPPQIYDAQLEEREHAIEEWKELIYKEVMDWEERS 367
Query: 420 PTGHTSTDNSIRAVTGAAFPKEAS 443
G S AV+ A P ++S
Sbjct: 368 KNGVVKDQPSDAAVSSNATPSQSS 391
>CE17062 [T] KOG0660 Mitogen-activated protein kinase
Length = 448
Score = 120 bits (302), Expect = 5e-27
Identities = 95/362 (26%), Positives = 154/362 (42%), Gaps = 54/362 (14%)
Query: 55 YREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNHKNI 114
Y + LG+G +G V + T +VAIK+ + + RE+ +L+ + H N+
Sbjct: 49 YNSLKPLGEGAYGVVCTAEYEPTGDRVAIKKFFRPFQSTIHAKRTYRELKLLRTLQHDNV 108
Query: 115 VKLIEIVYDESPTPKTDSTSPRPV---GNYHGNNTANQQKL--ITGKHFFMILPYMVSDL 169
+++I++ TP D++S V G++ N K+ +T + +++ Y V L
Sbjct: 109 LEMIDVF-----TPDPDASSLNNVYFVSVLMGSDLQNIMKIQRLTDEQIQLLI-YQV--L 160
Query: 170 TGLLHNPRVEFGMADVKNIMLQLLEGIN-----YIHCNKFLHRDIKTANILIDHKGVVK- 223
GL + F + ++ + N YIH +HRD+K +NI ++ + VK
Sbjct: 161 RGLKYMSHQNFNSTIILKKLMHPFQRRNTRFRLYIHSAGIIHRDLKPSNIAVNERCEVKV 220
Query: 224 ----------------IADFGLARNYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIV 267
I DFGLAR A+ T V TRWYRAPEI+
Sbjct: 221 FLSFSQLSFLILSFFKILDFGLAR---------------AQDAEMTGYVATRWYRAPEIM 265
Query: 268 LGDRHYTTAVDIWGIGCVFAEFFEKKPILQGQTDIDQGHVIFKLMGTPSMDEWGLAYHLP 327
L HYT VD+W +GC+ AE +P+ G IDQ I ++GTP + W
Sbjct: 266 LNWMHYTQTVDVWSVGCILAELVSGRPLFPGDDHIDQLTKIMSVVGTPKEEFWSKIQSEE 325
Query: 328 GSELTKTNYKSTLQERFSKAL---NETGXXXXXXXXXXDPYKRVTAMKAKKHPFFFEEPL 384
K N +++ F + DP +R++ A +H + E +
Sbjct: 326 ARNYIK-NRSPIIRQDFVTLFPMASPYALELLEMMLILDPDRRISVSSALRHDYLREYSV 384
Query: 385 PN 386
PN
Sbjct: 385 PN 386
>At5g19010 [T] KOG0660 Mitogen-activated protein kinase
Length = 567
Score = 120 bits (302), Expect = 5e-27
Identities = 84/270 (31%), Positives = 123/270 (45%), Gaps = 37/270 (13%)
Query: 53 NNYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNHK 112
+ YR EE +G+G++G V T KVAIK+I E REI +L+ + H
Sbjct: 23 SRYRIEEVIGKGSYGVVCSAYDTHTGEKVAIKKINDIFEHVSDATRILREIKLLRLLRHP 82
Query: 113 NIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGL 172
+IV++ I+ S D +++ M SDL +
Sbjct: 83 DIVEIKHILLPPSRREFRD--------------------------IYVVFELMESDLHQV 116
Query: 173 LHNPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLARN 232
+ + + + QLL G+ YIH HRD+K NIL + +KI DFGLAR
Sbjct: 117 I-KANDDLTPEHYQFFLYQLLRGLKYIHTANVFHRDLKPKNILANADCKLKICDFGLARV 175
Query: 233 YYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGD-RHYTTAVDIWGIGCVFAEFFE 291
+ P + +T V TRWYRAPE+ YT A+DIW IGC+FAE
Sbjct: 176 AFNDTPTAIF---------WTDYVATRWYRAPELCGSFFSKYTPAIDIWSIGCIFAELLT 226
Query: 292 KKPILQGQTDIDQGHVIFKLMGTPSMDEWG 321
KP+ G+ + Q ++ ++GTPS + G
Sbjct: 227 GKPLFPGKNVVHQLDLMTDMLGTPSAEAIG 256
>Hs4506089 [T] KOG0660 Mitogen-activated protein kinase
Length = 557
Score = 120 bits (301), Expect = 6e-27
Identities = 94/333 (28%), Positives = 149/333 (44%), Gaps = 34/333 (10%)
Query: 59 EKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNHKNIVKLI 118
+ LG G G V + RKVA+K+I + + + A REI I++R++H NIVK+
Sbjct: 24 QPLGFGVNGLVLSAVDSRACRKVAVKKIALSDARSMKH--ALREIKIIRRLDHDNIVKVY 81
Query: 119 EIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGLLHNPRV 178
E++ PK T Q +L +++ YM +DL LL +
Sbjct: 82 EVL-----GPK---------------GTDLQGELFKFSVAYIVQEYMETDLARLLEQGTL 121
Query: 179 EFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVV-KIADFGLARNYYGSP 237
A K M QLL G+ YIH LHRD+K ANI I + +V KI DFGLAR
Sbjct: 122 AEEHA--KLFMYQLLRGLKYIHSANVLHRDLKPANIFISTEDLVLKIGDFGLARIV---D 176
Query: 238 PNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFEKKPILQ 297
+ + G G +VT+WYR+P ++L +YT A+D+W GC+ AE + +
Sbjct: 177 QHYSHKGYLSEG------LVTKWYRSPRLLLSPNNYTKAIDMWAAGCILAEMLTGRMLFA 230
Query: 298 GQTDIDQGHVIFKLMGTPSMDEWGLAYHLPGSELTKTNYKSTLQERFSKALNETGXXXXX 357
G +++Q +I + + ++ + S ++ T + +N
Sbjct: 231 GAHELEQMQLILETIPVIREEDKDELLRVMPSFVSSTWEVKRPLRKLLPEVNSEAIDFLE 290
Query: 358 XXXXXDPYKRVTAMKAKKHPFFFEEPLPNAQLT 390
+P R+TA +HP+ P + T
Sbjct: 291 KILTFNPMDRLTAEMGLQHPYMSPYSCPEDEPT 323
>Hs21237736 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 424
Score = 120 bits (301), Expect = 6e-27
Identities = 110/444 (24%), Positives = 181/444 (39%), Gaps = 78/444 (17%)
Query: 25 VKDDKTGLEYIQVQSRENEKVYGVTKFLNNYREEEKLGQGTFGEVFKGIHLGTNRKVAIK 84
+ D K ++ VQ ++ L Y++ + +G G G V VA+K
Sbjct: 1 MSDSKCDSQFYSVQVADS-----TFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVK 55
Query: 85 RILVRAEKDLFPITAQREITILKRMNHKNIVKLIEIVYDESPTPKTDSTSPRPVGNYHGN 144
++ + A RE+ +LK +NHKNI+ L+ + TP
Sbjct: 56 KLSRPFQNQTHAKRAYRELVLLKCVNHKNIISLLNVF-----TP---------------- 94
Query: 145 NTANQQKLITGKHFFMILPYMVSDLTGLLHNPRVEFGMADVKNIMLQLLEGINYIHCNKF 204
Q+ L + ++++ M ++L ++H +E + ++ Q+L GI ++H
Sbjct: 95 ----QKTLEEFQDVYLVMELMDANLCQVIH---MELDHERMSYLLYQMLCGIKHLHSAGI 147
Query: 205 LHRDIKTANILIDHKGVVKIADFGLARNYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAP 264
+HRD+K +NI++ +KI DFGLAR A + T VVTR+YRAP
Sbjct: 148 IHRDLKPSNIVVKSDCTLKILDFGLART-------------ACTNFMMTPYVVTRYYRAP 194
Query: 265 EIVLGDRHYTTAVDIWGIGCVFAEFFEKKPILQGQTDIDQGHVIFKLMGTPSMDEWGLAY 324
E++LG Y VDIW +GC+ E + I QG IDQ + + + +GTPS A
Sbjct: 195 EVILG-MGYKENVDIWSVGCIMGELVKGCVIFQGTDHIDQWNKVIEQLGTPS------AE 247
Query: 325 HLPGSELTKTNYKST--------LQERF-----------SKALNETGXXXXXXXXXXDPY 365
+ + T NY +E F K DP
Sbjct: 248 FMKKLQPTVRNYVENRPKYPGIKFEELFPDWIFPSESERDKIKTSQARDLLSKMLVIDPD 307
Query: 366 KRVTAMKAKKHPFF------FEEPLPNAQLTLPNEECHESDIKRYKSEMNESMSQRPPSA 419
KR++ +A +HP+ E P Q+ E E I+ +K + + + +
Sbjct: 308 KRISVDEALRHPYITVWYDPAEAEAPPPQIYDAQLEEREHAIEEWKELIYKEVMDWEERS 367
Query: 420 PTGHTSTDNSIRAVTGAAFPKEAS 443
G S AV+ A P ++S
Sbjct: 368 KNGVVKDQPSDAAVSSNATPSQSS 391
>At3g18040 [T] KOG0660 Mitogen-activated protein kinase
Length = 613
Score = 120 bits (301), Expect = 6e-27
Identities = 90/301 (29%), Positives = 137/301 (44%), Gaps = 44/301 (14%)
Query: 23 TVVKD-DKTGLEYIQVQSRENEKVYGVTKFLNNYRE------EEKLGQGTFGEVFKGIHL 75
++V+D D +GL I+V R + KF Y E +E +G+G++G V I
Sbjct: 87 SLVRDFDLSGLNCIRVSRRNYILMDPHKKFFTEYGEASRYQIQEVIGKGSYGVVASAIDT 146
Query: 76 GTNRKVAIKRILVRAEKDLFPITAQREITILKRMNHKNIVKLIEIVYDESPTPKTDSTSP 135
+ KVAIK+I E REI +L+ + H +IV++ ++ S D
Sbjct: 147 HSGEKVAIKKINDVFEHVSDATRILREIKLLRLLRHPDIVEIKHVMLPPSRREFRD---- 202
Query: 136 RPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGLLHNPRVEFGMADVKNIMLQLLEG 195
+++ M SDL ++ + + + QLL G
Sbjct: 203 ----------------------IYVVFELMESDLHQVI-KANDDLTPEHYQFFLYQLLRG 239
Query: 196 INYIHCNKFLHRDIKTANILIDHKGVVKIADFGLARNYYGSPPNLKYPGGAGSGAKYTSV 255
+ +IH HRD+K NIL + +KI DFGLAR + P+ + +T
Sbjct: 240 LKFIHTANVFHRDLKPKNILANSDCKLKICDFGLARVSFNDAPSAIF---------WTDY 290
Query: 256 VVTRWYRAPEIVLGD-RHYTTAVDIWGIGCVFAEFFEKKPILQGQTDIDQGHVIFKLMGT 314
V TRWYRAPE+ YT A+DIW IGC+FAE KP+ G+ + Q ++ L+GT
Sbjct: 291 VATRWYRAPELCGSFFSKYTPAIDIWSIGCIFAEMLTGKPLFPGKNVVHQLDIMTDLLGT 350
Query: 315 P 315
P
Sbjct: 351 P 351
>At3g14720 [T] KOG0660 Mitogen-activated protein kinase
Length = 586
Score = 120 bits (301), Expect = 6e-27
Identities = 139/576 (24%), Positives = 222/576 (38%), Gaps = 104/576 (18%)
Query: 53 NNYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNHK 112
N YR E +G+G++G V I T KVAIK+I E + RE+ +L+ + H
Sbjct: 11 NRYRILEVIGKGSYGVVCAAIDTQTGEKVAIKKINDVFEHVSDALRILREVKLLRLLRHP 70
Query: 113 NIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGL 172
+IV++ I+ P K + K +++ M SDL +
Sbjct: 71 DIVEIKSIML---PPSKREF-----------------------KDIYVVFELMESDLHQV 104
Query: 173 LHNPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLARN 232
+ + + + Q+L + Y+H HRD+K NIL + +K+ DFGLAR
Sbjct: 105 I-KANDDLTREHHQFFLYQMLRALKYMHTANVYHRDLKPKNILANANCKLKVCDFGLARV 163
Query: 233 YYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGD-RHYTTAVDIWGIGCVFAEFFE 291
+ P + +T V TRWYRAPE+ YT A+DIW IGC+FAE
Sbjct: 164 SFNDTPTTVF---------WTDYVATRWYRAPELCGSFCSKYTPAIDIWSIGCIFAEVLT 214
Query: 292 KKPILQGQTDIDQGHVIFKLMGTPSMDE-WGLAYHLPGSELTKTNYKSTL--QERFSKAL 348
KP+ G++ + Q +I L+GTP + G+ L + K+ + ++F A
Sbjct: 215 GKPLFPGKSVVHQLDLITDLLGTPKSETIAGVRNEKARKYLNEMRKKNLVPFSQKFPNA- 273
Query: 349 NETGXXXXXXXXXXDPYKRVTAMKAKKHPFF----------FEEPLPNAQLTLPNEECHE 398
+ DP R TA +A P+F +P+ + +
Sbjct: 274 DPLALRLLQRLLAFDPKDRPTAAEALADPYFKCLAKVEREPSCQPISKMEFEFERRRLTK 333
Query: 399 SDIKR-------------YKSEMNESMSQRPPSAPTGHTS------TDNSIRAVTGAAFP 439
DI+ K MN S + GH +NS +G P
Sbjct: 334 DDIRELIYREILEYHPQLLKDYMNSEGSSFLYPSAIGHLRKQFAYLEENS--GKSGPVIP 391
Query: 440 KEASIPKAPRPEHIKSTI--PAQPSASRYNGAATQNIPKEP-----IPT----APLPKGP 488
+ PR S + AQPS N + ++ + EP +P+ + P GP
Sbjct: 392 PDRKHASLPRSAVHSSAVNSNAQPS---LNASDSRRVSIEPSRNGVVPSTSAYSTKPLGP 448
Query: 489 KNSIPTG-PNKLP------PNPRDSYASKYPAESRF-----------GVNTRITTESYNA 530
+P+G P ++ N R+ S Y A + + N + N
Sbjct: 449 PPRVPSGKPGRVVESSVTYENDRNLKESSYDARTSYYRSTVLPPQTVSPNCYFLPNTMNQ 508
Query: 531 GKRYRNRGGWETGRDSLNYNNNYAPPADRSHHPTIQ 566
KR + + N A PA+ + +P +Q
Sbjct: 509 EKRSGTEAASQPKPQFVPTQCNSAKPAELNPNPYVQ 544
>At1g06390 [G] KOG0658 Glycogen synthase kinase-3
Length = 407
Score = 120 bits (301), Expect = 6e-27
Identities = 98/355 (27%), Positives = 155/355 (43%), Gaps = 64/355 (18%)
Query: 47 GVTKFLNNYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILV-RAEKDLFPITAQREITI 105
G K +Y E +G G+FG VF+ L T VAIK++L R K+ RE+ +
Sbjct: 62 GEPKQTISYMAERVVGTGSFGIVFQAKCLETGESVAIKKVLQDRRYKN-------RELQL 114
Query: 106 LKRMNHKNIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYM 165
++ M+H N++ L + +T ++ +L +++ Y+
Sbjct: 115 MRPMDHPNVISLKHCFF----------------------STTSRDELFLN----LVMEYV 148
Query: 166 VSDLTGLLHN---PRVEFGMADVKNIMLQLLEGINYIHCNKFL-HRDIKTANILID---H 218
L +L + + VK Q+ G+ YIH + HRD+K N+L+D H
Sbjct: 149 PETLYRVLRHYTSSNQRMPIFYVKLYTYQIFRGLAYIHTVPGVCHRDVKPQNLLVDPLTH 208
Query: 219 KGVVKIADFGLARNYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVD 278
+ VK+ DFG A+ PN+ Y + +R+YRAPE++ G YT ++D
Sbjct: 209 Q--VKLCDFGSAKVLVKGEPNISY-------------ICSRYYRAPELIFGATEYTASID 253
Query: 279 IWGIGCVFAEFFEKKPILQGQTDIDQGHVIFKLMGTPSMDEWGLAYHLPGSELTKTNYKS 338
IW GCV AE +P+ G+ +DQ I K++GTP+ +E T +
Sbjct: 254 IWSAGCVLAELLLGQPLFPGENSVDQLVEIIKVLGTPTREE----IRCMNPNYTDFRFPQ 309
Query: 339 ----TLQERFSKALNETGXXXXXXXXXXDPYKRVTAMKAKKHPFFFEEPLPNAQL 389
+ F K + P R TA++A HPFF E PNA+L
Sbjct: 310 IKAHPWHKVFHKRMPPEAIDLASRLLQYSPSLRCTALEACAHPFFNELREPNARL 364
>At5g26751 [G] KOG0658 Glycogen synthase kinase-3
Length = 413
Score = 120 bits (300), Expect = 8e-27
Identities = 99/352 (28%), Positives = 149/352 (42%), Gaps = 58/352 (16%)
Query: 47 GVTKFLNNYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILV-RAEKDLFPITAQREITI 105
G K +Y E +G G+FG VF+ L T VAIK++L R K+ RE+
Sbjct: 61 GQPKQTISYMAERVVGHGSFGVVFQAKCLETGETVAIKKVLQDRRYKN-------RELQT 113
Query: 106 LKRMNHKNIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYM 165
++ ++H N+V L + T + D V Y +P
Sbjct: 114 MRLLDHPNVVSLKHCFFS---TTEKDELYLNLVLEY--------------------VPET 150
Query: 166 VSDLTGLLHNPRVEFGMADVKNIMLQLLEGINYIH-CNKFLHRDIKTANILID-HKGVVK 223
V + + + VK Q+ ++YIH C HRDIK N+L++ H VK
Sbjct: 151 VHRVIKHYNKLNQRMPLIYVKLYTYQIFRALSYIHRCIGVCHRDIKPQNLLVNPHTHQVK 210
Query: 224 IADFGLARNYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIG 283
+ DFG A+ PN+ Y + +R+YRAPE++ G YTTA+D+W G
Sbjct: 211 LCDFGSAKVLVKGEPNISY-------------ICSRYYRAPELIFGATEYTTAIDVWSAG 257
Query: 284 CVFAEFFEKKPILQGQTDIDQGHVIFKLMGTPSMDEWGLAYHLPGSELTKTNYK------ 337
CV AE +P+ G++ +DQ I K++GTP+ +E + T +K
Sbjct: 258 CVLAELLLGQPLFPGESGVDQLVEIIKVLGTPTREE------IKCMNPNYTEFKFPQIKA 311
Query: 338 STLQERFSKALNETGXXXXXXXXXXDPYKRVTAMKAKKHPFFFEEPLPNAQL 389
+ F K + P R A+ HPFF E PNA+L
Sbjct: 312 HPWHKIFHKRMPPEAVDLVSRLLQYSPNLRSAALDTLVHPFFDELRDPNARL 363
>CE29020 [T] KOG0660 Mitogen-activated protein kinase
Length = 470
Score = 119 bits (298), Expect = 1e-26
Identities = 97/372 (26%), Positives = 157/372 (42%), Gaps = 47/372 (12%)
Query: 58 EEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMN-HKNIVK 116
+++LG+G +G V+K + VA+K+I RE+ L+ H N++K
Sbjct: 16 QKRLGKGAYGIVWKAYDKRSRETVALKKIFDAFRNPTDSQRTFREVMFLQEFGKHPNVIK 75
Query: 117 LIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGLLHNP 176
L I + +N + ++ +M +DL ++
Sbjct: 76 LYNI--------------------FRADND---------RDIYLAFEFMEADLHNVIKKG 106
Query: 177 RVEFGMADVKN--IMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLARNYY 234
+ + DV IM QL I ++H LHRD+K +N+L+D VK+ADFGLAR+
Sbjct: 107 SI---LKDVHKQYIMCQLFRAIRFLHSGNVLHRDLKPSNVLLDADCRVKLADFGLARSLS 163
Query: 235 GSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFEKKP 294
YP G T V TRWYR+PEI+L + YT VD+W +GC+ AE +
Sbjct: 164 SLED---YPEGQKM-PDLTEYVATRWYRSPEILLAAKRYTKGVDMWSLGCILAEMLIGRA 219
Query: 295 ILQGQTDIDQGHVIFKLMGTPS-MDEWGLAYHLPGSELTKTNYKSTLQERFSKALNETGX 353
+ G + I+Q I + PS D + H S L K + ++T
Sbjct: 220 LFPGSSTINQIERIMNTIAKPSRADIASIGSHYAASVLEKMPQRPRKPLDLIITQSQTAA 279
Query: 354 -XXXXXXXXXDPYKRVTAMKAKKHPFFF------EEPLPNAQLTLPNEECHESDIKRYKS 406
P KR+T + HP+ EEP+ N ++ P + + I Y+
Sbjct: 280 IDMVQRLLIFAPQKRLTVEQCLVHPYVVQFHNPSEEPVLNYEVYPPLPDHIQLSIDDYRD 339
Query: 407 EMNESMSQRPPS 418
+ E + ++ S
Sbjct: 340 RLYEMIDEKKAS 351
>YNL307c [G] KOG0658 Glycogen synthase kinase-3
Length = 375
Score = 118 bits (296), Expect = 2e-26
Identities = 98/349 (28%), Positives = 154/349 (44%), Gaps = 58/349 (16%)
Query: 56 REEEKLGQGTFGEVFKGIHLGTNRK-----VAIKRILVRAEKDLFPITAQREITILKRMN 110
+E K+G+G FG V + +L ++K AIK++ E RE+ IL+ +
Sbjct: 36 KEYRKIGRGAFGTVVQA-YLTQDKKNWLGPFAIKKVPAHTEYK------SRELQILRIAD 88
Query: 111 HKNIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLT 170
H NIVKL Y + + Q + LP +
Sbjct: 89 HPNIVKL----------------------QYFFTHLSPQDNKVYQHLAMECLPETLQIEI 126
Query: 171 GLLHNPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHK-GVVKIADFGL 229
++E + ++ Q+ G+ Y+H HRDIK +N+L+D + GV+KI DFG
Sbjct: 127 NRYVTNKLEMPLKHIRLYTYQIARGMLYLHGLGVCHRDIKPSNVLVDPETGVLKICDFGS 186
Query: 230 ARNYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEF 289
A+ + P++ Y + +R+YRAPE+++G YTT +DIWG+GCV E
Sbjct: 187 AKKLEHNQPSISY-------------ICSRFYRAPELIIGCTQYTTQIDIWGLGCVMGEM 233
Query: 290 FEKKPILQGQTDIDQGHVIFKLMGTPSMDEWGLAYHLP---GSELTKTNYKSTLQERFSK 346
K I QGQ + Q I KL+G P D+ + + P G +K + + Q+RF K
Sbjct: 234 LIGKAIFQGQEPLLQLREIAKLLGPP--DKRFIFFSNPAYDGPLFSKPLFSGSSQQRFEK 291
Query: 347 ALNET---GXXXXXXXXXXDPYKRVTAMKAKKHPFFFEEPLPNAQLTLP 392
+ G +P +R++ + H FF E L N LP
Sbjct: 292 YFGHSGPDGIDLLMKILVYEPQQRLSPRRILAHQFFNE--LRNDDTFLP 338
>HsM20070143 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 424
Score = 118 bits (296), Expect = 2e-26
Identities = 109/444 (24%), Positives = 180/444 (39%), Gaps = 78/444 (17%)
Query: 25 VKDDKTGLEYIQVQSRENEKVYGVTKFLNNYREEEKLGQGTFGEVFKGIHLGTNRKVAIK 84
+ D K ++ VQ ++ L Y++ + +G G G V VA+K
Sbjct: 1 MSDSKCDSQFYSVQVADS-----TFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVK 55
Query: 85 RILVRAEKDLFPITAQREITILKRMNHKNIVKLIEIVYDESPTPKTDSTSPRPVGNYHGN 144
++ + A RE+ +LK +NHKNI+ L+ + TP
Sbjct: 56 KLSRPFQNQTHAKRAYRELVLLKCVNHKNIISLLNVF-----TP---------------- 94
Query: 145 NTANQQKLITGKHFFMILPYMVSDLTGLLHNPRVEFGMADVKNIMLQLLEGINYIHCNKF 204
Q+ L + ++++ M ++L ++H +E + ++ Q+L GI ++H
Sbjct: 95 ----QKTLEEFQDVYLVMELMDANLCQVIH---MELDHERMSYLLYQMLCGIKHLHSAGI 147
Query: 205 LHRDIKTANILIDHKGVVKIADFGLARNYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAP 264
+HRD+K +NI++ +KI DFGLAR A + T VVTR+YRAP
Sbjct: 148 IHRDLKPSNIVVKSDCTLKILDFGLART-------------ACTNFMMTPYVVTRYYRAP 194
Query: 265 EIVLGDRHYTTAVDIWGIGCVFAEFFEKKPILQGQTDIDQGHVIFKLMGTPSMDEWGLAY 324
E++LG Y VDIW +GC+ E + I QG IDQ + + + +GTPS A
Sbjct: 195 EVILG-MGYKENVDIWSVGCIMGELVKGCVIFQGTDHIDQWNKVIEQLGTPS------AE 247
Query: 325 HLPGSELTKTNYKST--------LQERF-----------SKALNETGXXXXXXXXXXDPY 365
+ + T NY +E F K DP
Sbjct: 248 FMKKLQPTVRNYVENRPKYPGIKFEELFPDWIFPSESERDKIKTSQARDLLSKMLVIDPD 307
Query: 366 KRVTAMKAKKHPFF------FEEPLPNAQLTLPNEECHESDIKRYKSEMNESMSQRPPSA 419
KR++ +A +HP+ E P Q+ E E I+ +K + + + +
Sbjct: 308 KRISVDEALRHPYITVWYDPAEAEAPPPQIYDAQLEEREHAIEEWKELIYKEVMDWEERS 367
Query: 420 PTGHTSTDNSIRAVTGAAFPKEAS 443
G AV+ A P ++S
Sbjct: 368 KNGVVKDQPPDAAVSSNATPSQSS 391
>Hs17452757 [UT] KOG0662 Cyclin-dependent kinase CDK5
Length = 366
Score = 117 bits (294), Expect = 4e-26
Identities = 96/378 (25%), Positives = 165/378 (43%), Gaps = 62/378 (16%)
Query: 12 KYKIGKVKQIPTVVKDDKTGLEYIQVQSRENEKVYGVTKFLNNYREEEKLGQGTFGEVFK 71
+Y +GK K + D K Y+ + +R + + ++ EK+G+GT+G VFK
Sbjct: 36 EYHLGKRK---SQQDDSKMAGNYV-LWARVTVLASNILSREDEQKKLEKIGEGTYGTVFK 91
Query: 72 GIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNHKNIVKLIEIVYDESPTPKTD 131
+ T+ VA+K + + D P +A REI +LK + HKNIV+L ++++ +
Sbjct: 92 AKNWETHEIVALKWVRLDDNDDGVPSSALREICLLKELKHKNIVRLHDLLHSD------- 144
Query: 132 STSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGLLHNPRVEFGMADVKNIMLQ 191
K ++ + L + + VK+ + Q
Sbjct: 145 ------------------------KKLTLVFKFCHQHLKKYFDSCNGDLDPEIVKSFLFQ 180
Query: 192 LLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLARNYYGSPPNLKYPGGAGSGAK 251
LL+G+ + H L RD+K N+LI+ G +K+ADFGL+R +G P + Y
Sbjct: 181 LLKGLGFCHSRNVLRRDLKPQNLLINRNGELKLADFGLSR-AFGIP--ICY--------- 228
Query: 252 YTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFEKK-PILQGQTDIDQGHVIFK 310
+ G + Y+T++D+W GC+FAE P+ G DQ IF
Sbjct: 229 --------------VFFGAKLYSTSIDLWSAGCIFAELANAGWPLFPGNDVDDQLKRIFW 274
Query: 311 LMGTPSMDEWGLAYHLPGSELTKTNYKSTLQERFSKALNETGXXXXXXXXXXDPYKRVTA 370
L+G + ++W LP +L +T L+ TG +P + ++A
Sbjct: 275 LLGMLTKEQWPSMTKLPDYKLYPLYPATTSLVNIVPKLSATGRDLLQNLLKCNPCQCISA 334
Query: 371 MKAKKHPFFFEEPLPNAQ 388
+A ++P+F + P AQ
Sbjct: 335 EEALQYPYFSDFCPPWAQ 352
>SPBC119.08 [T] KOG0660 Mitogen-activated protein kinase
Length = 422
Score = 117 bits (292), Expect = 7e-26
Identities = 94/331 (28%), Positives = 151/331 (45%), Gaps = 43/331 (12%)
Query: 54 NYREEEKLGQGTFGEVFKGIHLGTNRK--VAIKRILVRAEKDLFPITAQREITILKRM-N 110
N++ ++LGQG +G V ++ + + VAIK+I K + A REI +L N
Sbjct: 20 NFKVVKELGQGAYGIVCAARNVASKDQEAVAIKKITNVFSKSILTKRALREIKLLIHFRN 79
Query: 111 HKNIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLT 170
H+NI +YD D +P Y+ N ++L M +DL
Sbjct: 80 HRNIT----CIYD------LDIINP-----YNFNEVYIYEEL------------MEADLN 112
Query: 171 GLLHNPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLA 230
++ + + A ++ + Q+L G+ YIH +HRD+K N+L++ +KI DFGLA
Sbjct: 113 AIIKSGQ-PLTDAHFQSFIYQILCGLKYIHSANVIHRDLKPGNLLVNADCELKICDFGLA 171
Query: 231 RNYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFF 290
R +P + PG T V TRWYRAPEI+L Y +D+W +GC+ AE
Sbjct: 172 RGCSENPE--ENPGFM------TEYVATRWYRAPEIMLSFSSYHKGIDVWSVGCILAELL 223
Query: 291 EKKPILQGQTDIDQGHVIFKLMGTPSMDEWGLAYHLPGSELTKTNYKS---TLQERFSKA 347
P+ +G+ + Q ++I +GTP + E ++ K + F KA
Sbjct: 224 GGTPLFKGKDFVHQLNLILHQLGTPDEETLSHISSSRAQEYVRSLPKQRPIPFETNFPKA 283
Query: 348 LNETGXXXXXXXXXXDPYKRVTAMKAKKHPF 378
N DP +R++ A +HP+
Sbjct: 284 -NPLALDLLAKLLAFDPNRRISVDDALEHPY 313
>Hs22051130 [G] KOG0658 Glycogen synthase kinase-3
Length = 483
Score = 117 bits (292), Expect = 7e-26
Identities = 79/266 (29%), Positives = 123/266 (45%), Gaps = 42/266 (15%)
Query: 55 YREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNHKNI 114
Y + + +G G+FG V++ T VAIK++L RE+ I+++++H NI
Sbjct: 119 YTDIKVIGNGSFGVVYQARLAETRELVAIKKVLQDKR------FKNRELQIMRKLDHCNI 172
Query: 115 VKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGLLH 174
V+L Y S K D V Y +P V +
Sbjct: 173 VRLRYFFY--SSGEKKDELYLNLVLEY--------------------VPETVYRVARHFT 210
Query: 175 NPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILID-HKGVVKIADFGLARNY 233
++ + VK M QL + YIH HRDIK N+L+D V+K+ DFG A+
Sbjct: 211 KAKLTIPILYVKVYMYQLFRSLAYIHSQGVCHRDIKPQNLLVDPDTAVLKLCDFGSAKQL 270
Query: 234 YGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFEKK 293
PN+ Y + +R+YRAPE++ G YT+++D+W GCV AE +
Sbjct: 271 VRGEPNVSY-------------ICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQ 317
Query: 294 PILQGQTDIDQGHVIFKLMGTPSMDE 319
PI G + +DQ I K++GTP+ ++
Sbjct: 318 PIFPGDSGVDQLVEIIKVLGTPTREQ 343
>Hs21361340 [G] KOG0658 Glycogen synthase kinase-3
Length = 433
Score = 117 bits (292), Expect = 7e-26
Identities = 100/384 (26%), Positives = 158/384 (41%), Gaps = 69/384 (17%)
Query: 54 NYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNHKN 113
+Y + + +G G+FG V++ + VAIK++L RE+ I+++++H N
Sbjct: 55 SYTDTKVIGNGSFGVVYQAKLCDSGELVAIKKVLQDKR------FKNRELQIMRKLDHCN 108
Query: 114 IVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGLL 173
IV+L Y S K D V +Y +P V +
Sbjct: 109 IVRLRYFFY--SSGEKKDEVYLNLVLDY--------------------VPETVYRVARHY 146
Query: 174 HNPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILID-HKGVVKIADFGLARN 232
+ + VK M QL + YIH HRDIK N+L+D V+K+ DFG A+
Sbjct: 147 SRAKQTLPVIYVKLYMYQLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQ 206
Query: 233 YYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFEK 292
PN+ Y + +R+YRAPE++ G YT+++D+W GCV AE
Sbjct: 207 LVRGEPNVSY-------------ICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLG 253
Query: 293 KPILQGQTDIDQGHVIFKLMGTPSMDEWGLAYHLPGSELTKTNYKSTLQERFSKALNETG 352
+PI G + +DQ I K++GTP+ ++ T+ + ++K + TG
Sbjct: 254 QPIFPGDSGVDQLVEIIKVLGTPTREQ----IREMNPNYTEFKFPQIKAHPWTKDSSGTG 309
Query: 353 XXXX-----------------XXXXXXDPYKRVTAMKAKKHPFFFEEPLPNAQLTLPNEE 395
P R+T ++A H FF E PN + LPN
Sbjct: 310 HFTSGVRVFRPRTPPEAIALCSRLLEYTPTARLTPLEACAHSFFDELRDPNVK--LPNGR 367
Query: 396 CHESDIKRYKSEMNESMSQRPPSA 419
D + + +S PP A
Sbjct: 368 ----DTPALFNFTTQELSSNPPLA 387
>Hs11995474 [G] KOG0658 Glycogen synthase kinase-3
Length = 483
Score = 117 bits (292), Expect = 7e-26
Identities = 79/266 (29%), Positives = 123/266 (45%), Gaps = 42/266 (15%)
Query: 55 YREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNHKNI 114
Y + + +G G+FG V++ T VAIK++L RE+ I+++++H NI
Sbjct: 119 YTDIKVIGNGSFGVVYQARLAETRELVAIKKVLQDKR------FKNRELQIMRKLDHCNI 172
Query: 115 VKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGLLH 174
V+L Y S K D V Y +P V +
Sbjct: 173 VRLRYFFY--SSGEKKDELYLNLVLEY--------------------VPETVYRVARHFT 210
Query: 175 NPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILID-HKGVVKIADFGLARNY 233
++ + VK M QL + YIH HRDIK N+L+D V+K+ DFG A+
Sbjct: 211 KAKLTIPILYVKVYMYQLFRSLAYIHSQGVCHRDIKPQNLLVDPDTAVLKLCDFGSAKQL 270
Query: 234 YGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFEKK 293
PN+ Y + +R+YRAPE++ G YT+++D+W GCV AE +
Sbjct: 271 VRGEPNVSY-------------ICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQ 317
Query: 294 PILQGQTDIDQGHVIFKLMGTPSMDE 319
PI G + +DQ I K++GTP+ ++
Sbjct: 318 PIFPGDSGVDQLVEIIKVLGTPTREQ 343
>Hs21237742 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 382
Score = 116 bits (291), Expect = 9e-26
Identities = 82/294 (27%), Positives = 137/294 (45%), Gaps = 47/294 (15%)
Query: 25 VKDDKTGLEYIQVQSRENEKVYGVTKFLNNYREEEKLGQGTFGEVFKGIHLGTNRKVAIK 84
+ D K ++ VQ ++ L Y++ + +G G G V VA+K
Sbjct: 1 MSDSKCDSQFYSVQVADS-----TFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVK 55
Query: 85 RILVRAEKDLFPITAQREITILKRMNHKNIVKLIEIVYDESPTPKTDSTSPRPVGNYHGN 144
++ + A RE+ +LK +NHKNI+ L+ + TP
Sbjct: 56 KLSRPFQNQTHAKRAYRELVLLKCVNHKNIISLLNVF-----TP---------------- 94
Query: 145 NTANQQKLITGKHFFMILPYMVSDLTGLLHNPRVEFGMADVKNIMLQLLEGINYIHCNKF 204
Q+ L + ++++ M ++L ++H +E + ++ Q+L GI ++H
Sbjct: 95 ----QKTLEEFQDVYLVMELMDANLCQVIH---MELDHERMSYLLYQMLCGIKHLHSAGI 147
Query: 205 LHRDIKTANILIDHKGVVKIADFGLARNYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAP 264
+HRD+K +NI++ +KI DFGLAR A + T VVTR+YRAP
Sbjct: 148 IHRDLKPSNIVVKSDCTLKILDFGLART-------------ACTNFMMTPYVVTRYYRAP 194
Query: 265 EIVLGDRHYTTAVDIWGIGCVFAEFFEKKPILQGQTDIDQGHVIFKLMGTPSMD 318
E++LG Y VDIW +GC+ AE K + G+ IDQ + + + +GTPS +
Sbjct: 195 EVILG-MGYKENVDIWSVGCIMAEMVLHKVLFPGRDYIDQWNKVIEQLGTPSAE 247
>At2g30980 [G] KOG0658 Glycogen synthase kinase-3
Length = 412
Score = 116 bits (291), Expect = 9e-26
Identities = 100/352 (28%), Positives = 148/352 (41%), Gaps = 58/352 (16%)
Query: 47 GVTKFLNNYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILV-RAEKDLFPITAQREITI 105
G K +Y E +G G+FG VF+ L T VAIK++L R K+ RE+ +
Sbjct: 64 GEPKQTISYMAERVVGTGSFGIVFQAKCLETGESVAIKKVLQDRRYKN-------RELQL 116
Query: 106 LKRMNHKNIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYM 165
++ M+H N+V L + T D V Y K T + M + Y
Sbjct: 117 MRLMDHPNVVSLKHCFFS---TTTRDELFLNLVMEYVPETLYRVLKHYTSSNQRMPIFY- 172
Query: 166 VSDLTGLLHNPRVEFGMADVKNIMLQLLEGINYIHCNKFL-HRDIKTANILID---HKGV 221
VK Q+ G+ YIH + HRD+K N+L+D H+
Sbjct: 173 -------------------VKLYTYQIFRGLAYIHTAPGVCHRDVKPQNLLVDPLTHQ-- 211
Query: 222 VKIADFGLARNYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWG 281
K+ DFG A+ N+ Y + +R+YRAPE++ G YT+++DIW
Sbjct: 212 CKLCDFGSAKVLVKGEANISY-------------ICSRYYRAPELIFGATEYTSSIDIWS 258
Query: 282 IGCVFAEFFEKKPILQGQTDIDQGHVIFKLMGTPSMDEWGLAYHLPGSELTKTNYKS--- 338
GCV AE +P+ G+ +DQ I K++GTP+ +E T +
Sbjct: 259 AGCVLAELLLGQPLFPGENSVDQLVEIIKVLGTPTREE----IRCMNPNYTDFRFPQIKA 314
Query: 339 -TLQERFSKALNETGXXXXXXXXXXDPYKRVTAMKAKKHPFFFEEPLPNAQL 389
+ F K + P R TA++A HPFF E PNA+L
Sbjct: 315 HPWHKVFHKRMPPEAIDLASRLLQYSPSLRCTALEACAHPFFNELREPNARL 366
>Hs4506081 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 422
Score = 116 bits (290), Expect = 1e-25
Identities = 77/264 (29%), Positives = 127/264 (47%), Gaps = 42/264 (15%)
Query: 52 LNNYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNH 111
L Y+ + +G G G V +R VAIK++ + A RE+ ++K +NH
Sbjct: 61 LKRYQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNH 120
Query: 112 KNIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTG 171
KNI+ L+ + TP Q+ L + ++++ M ++L
Sbjct: 121 KNIISLLNVF-----TP--------------------QKTLEEFQDVYLVMELMDANLCQ 155
Query: 172 LLHNPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLAR 231
++ ++E + ++ Q+L GI ++H +HRD+K +NI++ +KI DFGLAR
Sbjct: 156 VI---QMELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLAR 212
Query: 232 NYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFE 291
AG+ T VVTR+YRAPE++LG Y VDIW +GC+ E
Sbjct: 213 T-------------AGTSFMMTPYVVTRYYRAPEVILG-MGYKENVDIWSVGCIMGEMVR 258
Query: 292 KKPILQGQTDIDQGHVIFKLMGTP 315
K + G+ IDQ + + + +GTP
Sbjct: 259 HKILFPGRDYIDQWNKVIEQLGTP 282
>Hs21237739 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 382
Score = 116 bits (290), Expect = 1e-25
Identities = 82/294 (27%), Positives = 136/294 (45%), Gaps = 47/294 (15%)
Query: 25 VKDDKTGLEYIQVQSRENEKVYGVTKFLNNYREEEKLGQGTFGEVFKGIHLGTNRKVAIK 84
+ D K ++ VQ ++ L Y++ + +G G G V VA+K
Sbjct: 1 MSDSKCDSQFYSVQVADS-----TFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVK 55
Query: 85 RILVRAEKDLFPITAQREITILKRMNHKNIVKLIEIVYDESPTPKTDSTSPRPVGNYHGN 144
++ + A RE+ +LK +NHKNI+ L+ + TP
Sbjct: 56 KLSRPFQNQTHAKRAYRELVLLKCVNHKNIISLLNVF-----TP---------------- 94
Query: 145 NTANQQKLITGKHFFMILPYMVSDLTGLLHNPRVEFGMADVKNIMLQLLEGINYIHCNKF 204
Q+ L + ++++ M ++L ++H +E + ++ Q+L GI ++H
Sbjct: 95 ----QKTLEEFQDVYLVMELMDANLCQVIH---MELDHERMSYLLYQMLCGIKHLHSAGI 147
Query: 205 LHRDIKTANILIDHKGVVKIADFGLARNYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAP 264
+HRD+K +NI++ +KI DFGLAR A + T VVTR+YRAP
Sbjct: 148 IHRDLKPSNIVVKSDCTLKILDFGLART-------------ACTNFMMTPYVVTRYYRAP 194
Query: 265 EIVLGDRHYTTAVDIWGIGCVFAEFFEKKPILQGQTDIDQGHVIFKLMGTPSMD 318
E++LG Y VDIW +GC+ E + I QG IDQ + + + +GTPS +
Sbjct: 195 EVILG-MGYKENVDIWSVGCIMGELVKGCVIFQGTDHIDQWNKVIEQLGTPSAE 247
>Hs20986510 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 464
Score = 116 bits (290), Expect = 1e-25
Identities = 77/264 (29%), Positives = 127/264 (47%), Gaps = 42/264 (15%)
Query: 52 LNNYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNH 111
L Y+ + +G G G V +R VAIK++ + A RE+ ++K +NH
Sbjct: 61 LKRYQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNH 120
Query: 112 KNIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTG 171
KNI+ L+ + TP Q+ L + ++++ M ++L
Sbjct: 121 KNIISLLNVF-----TP--------------------QKTLEEFQDVYLVMELMDANLCQ 155
Query: 172 LLHNPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLAR 231
++ ++E + ++ Q+L GI ++H +HRD+K +NI++ +KI DFGLAR
Sbjct: 156 VI---QMELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLAR 212
Query: 232 NYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFE 291
AG+ T VVTR+YRAPE++LG Y VDIW +GC+ E
Sbjct: 213 T-------------AGTSFMMTPYVVTRYYRAPEVILG-MGYKENVDIWSVGCIMGEMVR 258
Query: 292 KKPILQGQTDIDQGHVIFKLMGTP 315
K + G+ IDQ + + + +GTP
Sbjct: 259 HKILFPGRDYIDQWNKVIEQLGTP 282
>Hs20986506 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 426
Score = 116 bits (290), Expect = 1e-25
Identities = 77/264 (29%), Positives = 127/264 (47%), Gaps = 42/264 (15%)
Query: 52 LNNYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNH 111
L Y+ + +G G G V +R VAIK++ + A RE+ ++K +NH
Sbjct: 23 LKRYQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNH 82
Query: 112 KNIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTG 171
KNI+ L+ + TP Q+ L + ++++ M ++L
Sbjct: 83 KNIISLLNVF-----TP--------------------QKTLEEFQDVYLVMELMDANLCQ 117
Query: 172 LLHNPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLAR 231
++ ++E + ++ Q+L GI ++H +HRD+K +NI++ +KI DFGLAR
Sbjct: 118 VI---QMELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLAR 174
Query: 232 NYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFE 291
AG+ T VVTR+YRAPE++LG Y VDIW +GC+ E
Sbjct: 175 T-------------AGTSFMMTPYVVTRYYRAPEVILG-MGYKENVDIWSVGCIMGEMVR 220
Query: 292 KKPILQGQTDIDQGHVIFKLMGTP 315
K + G+ IDQ + + + +GTP
Sbjct: 221 HKILFPGRDYIDQWNKVIEQLGTP 244
>At4g01370 [T] KOG0660 Mitogen-activated protein kinase
Length = 376
Score = 116 bits (290), Expect = 1e-25
Identities = 84/327 (25%), Positives = 150/327 (45%), Gaps = 56/327 (17%)
Query: 61 LGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNHKNIVKLIEI 120
+G+G +G V + T +VAIK+I + + REI +LK M+H+N++ + +I
Sbjct: 49 IGRGAYGIVCAATNSETGEEVAIKKIGNAFDNIIDAKRTLREIKLLKHMDHENVIAVKDI 108
Query: 121 VYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGLLHNPRVEF 180
+ +P + N+ +++ M +DL ++ + +
Sbjct: 109 I--------------KPPQRENFNDV------------YIVYELMDTDLHQIIRSNQP-- 140
Query: 181 GMAD--VKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLARNYYGSPP 238
+ D + + QLL G+ Y+H LHRD+K +N+L++ +K+ DFGLAR +
Sbjct: 141 -LTDDHCRFFLYQLLRGLKYVHSANVLHRDLKPSNLLLNANCDLKLGDFGLARTKSETDF 199
Query: 239 NLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFEKKPILQG 298
+Y VVTRWYRAPE++L YT A+DIW +GC+ E ++P+ G
Sbjct: 200 MTEY-------------VVTRWYRAPELLLNCSEYTAAIDIWSVGCILGETMTREPLFPG 246
Query: 299 QTDIDQGHVIFKLMGTPSMDEWGL-------AYHLPGSELTKTNYKSTLQERFSKALNET 351
+ + Q +I +L+G+P G Y + + N+ + + A++
Sbjct: 247 KDYVHQLRLITELIGSPDDSSLGFLRSDNARRYVRQLPQYPRQNFAARFPNMSAGAVD-- 304
Query: 352 GXXXXXXXXXXDPYKRVTAMKAKKHPF 378
DP +R+T +A HP+
Sbjct: 305 ---LLEKMLVFDPSRRITVDEALCHPY 328
>At1g18150 [T] KOG0660 Mitogen-activated protein kinase
Length = 589
Score = 116 bits (290), Expect = 1e-25
Identities = 86/299 (28%), Positives = 133/299 (43%), Gaps = 47/299 (15%)
Query: 28 DKTGLEYIQVQSRENEKV----YGVTKFL------NNYREEEKLGQGTFGEVFKGIHLGT 77
D +GL I V R + + G T+F N Y+ +E +G+G++G V + T
Sbjct: 67 DFSGLTLINVPKRNHLPMDPHKKGETEFFTEYGEANRYQIQEVVGKGSYGVVASAVDSHT 126
Query: 78 NRKVAIKRILVRAEKDLFPITAQREITILKRMNHKNIVKLIEIVYDESPTPKTDSTSPRP 137
+VAIK+I E REI +L+ + H ++V++ I+ S D
Sbjct: 127 GERVAIKKINDVFEHVSDATRILREIKLLRLLRHPDVVEIKHIMLPPSRREFRD------ 180
Query: 138 VGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGLLHNPRVEFGMADVKNIMLQLLEGIN 197
+++ M SDL ++ + + + QLL G+
Sbjct: 181 --------------------IYVVFELMESDLHQVI-KANDDLTPEHYQFFLYQLLRGLK 219
Query: 198 YIHCNKFLHRDIKTANILIDHKGVVKIADFGLARNYYGSPPNLKYPGGAGSGAKYTSVVV 257
Y+H HRD+K NIL + +KI DFGLAR + P + +T V
Sbjct: 220 YVHAANVFHRDLKPKNILANADCKLKICDFGLARVSFNDAPTAIF---------WTDYVA 270
Query: 258 TRWYRAPEIVLG-DRHYTTAVDIWGIGCVFAEFFEKKPILQGQTDIDQGHVIFKLMGTP 315
TRWYRAPE+ YT A+DIW +GC+FAE KP+ G+ + Q ++ +GTP
Sbjct: 271 TRWYRAPELCGSFFSKYTPAIDIWSVGCIFAEMLLGKPLFPGKNVVHQLDLMTDFLGTP 329
>YHR030c [T] KOG0660 Mitogen-activated protein kinase
Length = 484
Score = 115 bits (288), Expect = 2e-25
Identities = 115/472 (24%), Positives = 194/472 (40%), Gaps = 99/472 (20%)
Query: 59 EKLGQGTFGEVFKG--IHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMN-HKNIV 115
+++G G +G V + VAIK++ K L + RE+ +L+ HKNI
Sbjct: 27 KEIGHGAYGIVCSARFAEAAEDTTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRGHKNIT 86
Query: 116 KL--IEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGLL 173
L ++IV+ P G+ +G ++ M D+ ++
Sbjct: 87 CLYDMDIVF-------------YPDGSING--------------LYLYEELMECDMHQII 119
Query: 174 HNPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLARNY 233
+ + A ++ Q+L G+ YIH LHRD+K N+L++ +KI DFGLAR Y
Sbjct: 120 KSGQ-PLTDAHYQSFTYQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGY 178
Query: 234 YGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFEKK 293
+P + T V TRWYRAPEI+L + YT A+D+W GC+ AEF K
Sbjct: 179 SENPVE--------NSQFLTEYVATRWYRAPEIMLSYQGYTKAIDVWSAGCILAEFLGGK 230
Query: 294 PILQGQTDIDQGHVIFKLMGTP---------SMDEWGLAYHLPGSELTKTNYKSTLQERF 344
PI +G+ ++Q + I +++GTP S + + L + K + +
Sbjct: 231 PIFKGKDYVNQLNQILQVLGTPPDETLRRIGSKNVQDYIHQL--GFIPKVPFVNLYPNAN 288
Query: 345 SKALNETGXXXXXXXXXXDPYKRVTAMKAKKHPFF------FEEPLPNAQLTLPNEECHE 398
S+AL+ DP KR+T +A +HP+ +EP+ + + E ++
Sbjct: 289 SQALD-----LLEQMLAFDPQKRITVDEALEHPYLSIWHDPADEPVCSEKFEFSFESVND 343
Query: 399 -SDIK-----------------------RYKSEMNESMSQRPPSAPTGHTSTDNSIRAVT 434
D+K + + + + Q+ + DN A +
Sbjct: 344 MEDLKQMVIQEVQDFRLFVRQPLLEEQRQLQLQQQQQQQQQQQQQQQQPSDVDNGNAAAS 403
Query: 435 GAAFPKEASIPKAPRPEHIKSTIPAQPSASRYNGAATQNIPKEPIPTAPLPK 486
+PK+ + S P Q S G +QN+P+ P P+
Sbjct: 404 EENYPKQMATS--------NSVAPQQESF----GIHSQNLPRHDADFPPRPQ 443
>SPAC3C7.06c [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 650
Score = 115 bits (288), Expect = 2e-25
Identities = 78/268 (29%), Positives = 127/268 (47%), Gaps = 50/268 (18%)
Query: 55 YREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMN-HKN 113
Y K+G GTFG V+ +++V + + + + T RE+ L R++ ++N
Sbjct: 36 YNVVRKVGDGTFGSVYLATTKTPSKEVVAIKSMKKKLAKVSDATRLREVHSLLRLSENEN 95
Query: 114 IVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGLL 173
IV + ++ D+ + +++ ++ +L L+
Sbjct: 96 IVNIFDLYIDQF------------------------------RCLHIVMEFLDCNLYQLI 125
Query: 174 HNPRVE-FGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGV-----VKIADF 227
+ + + V++IM Q+ +G+N+IH N F HRD+K NILI VKIADF
Sbjct: 126 STRKNDPLTLEQVQDIMRQIFKGLNHIHTNGFFHRDMKPENILISSNSDSSSFNVKIADF 185
Query: 228 GLARNYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFA 287
GLAR PP YT V TRWYRAPE++L D +Y+ VDI+ GC+
Sbjct: 186 GLAREINSRPP-------------YTEYVSTRWYRAPELLLRDSYYSFPVDIYAAGCMAF 232
Query: 288 EFFEKKPILQGQTDIDQGHVIFKLMGTP 315
E +PI G D DQ + + +++G+P
Sbjct: 233 EIATLQPIFPGNDDFDQLYKMCEILGSP 260
>HsM4504163 [G] KOG0658 Glycogen synthase kinase-3
Length = 420
Score = 115 bits (288), Expect = 2e-25
Identities = 78/267 (29%), Positives = 124/267 (46%), Gaps = 42/267 (15%)
Query: 54 NYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNHKN 113
+Y + + +G G+FG V++ + VAIK++L RE+ I+++++H N
Sbjct: 55 SYTDTKVIGNGSFGVVYQAKLCDSGELVAIKKVLQDKR------FKNRELQIMRKLDHCN 108
Query: 114 IVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGLL 173
IV+L Y S K D V +Y +P V +
Sbjct: 109 IVRLRYFFY--SSGEKKDEVYLNLVLDY--------------------VPETVYRVARHY 146
Query: 174 HNPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILID-HKGVVKIADFGLARN 232
+ + VK M QL + YIH HRDIK N+L+D V+K+ DFG A+
Sbjct: 147 SRAKQTLPVIYVKLYMYQLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQ 206
Query: 233 YYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFEK 292
PN+ Y + +R+YRAPE++ G YT+++D+W GCV AE
Sbjct: 207 LVRGEPNVSY-------------ICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLG 253
Query: 293 KPILQGQTDIDQGHVIFKLMGTPSMDE 319
+PI G + +DQ I K++GTP+ ++
Sbjct: 254 QPIFPGDSGVDQLVEIIKVLGTPTREQ 280
>YDL079c [G] KOG0658 Glycogen synthase kinase-3
Length = 501
Score = 115 bits (287), Expect = 3e-25
Identities = 82/272 (30%), Positives = 126/272 (46%), Gaps = 52/272 (19%)
Query: 54 NYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILV-RAEKDLFPITAQREITILKRMNHK 112
+Y E +G G+FG V + + TN+KVAIK++L R K+ RE+ +K + H
Sbjct: 163 SYPTTEVVGHGSFGVVVTTVIIETNQKVAIKKVLQDRRYKN-------RELETMKMLCHP 215
Query: 113 NIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGL 172
N V L Y++ + + ++L YM L
Sbjct: 216 NTVGLQYYFYEKDEEDEV--------------------------YLNLVLDYMPQSLYQR 249
Query: 173 LH---NPRVEFGMADVKNIMLQLLEGINYIH-CNKFLHRDIKTANILIDHKGV-VKIADF 227
L N +++ ++K QL + +NY+H + HRDIK N+L+D KI DF
Sbjct: 250 LRHFVNLKMQMPRVEIKFYAYQLFKALNYLHNVPRICHRDIKPQNLLVDPTTFSFKICDF 309
Query: 228 GLARNYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFA 287
G A+ PN+ Y + +R+YRAPE++ G +Y+ VD+W CV A
Sbjct: 310 GSAKCLKPDQPNVSY-------------ICSRYYRAPELMFGATNYSNQVDVWSSACVIA 356
Query: 288 EFFEKKPILQGQTDIDQGHVIFKLMGTPSMDE 319
E KP+ G++ IDQ I K+MG P+ DE
Sbjct: 357 ELLLGKPLFSGESGIDQLVEIIKIMGIPTKDE 388
>Hs20502986 [T] KOG0660 Mitogen-activated protein kinase
Length = 277
Score = 115 bits (287), Expect = 3e-25
Identities = 80/285 (28%), Positives = 124/285 (43%), Gaps = 49/285 (17%)
Query: 50 KFLNNYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRM 109
+ + Y +LGQG +G V+K + T VAIK+I REIT+L+
Sbjct: 8 RIVRRYLLRRQLGQGAYGIVWKAVDRRTGEVVAIKKIFDAFRDKTDAQRTFREITLLQEF 67
Query: 110 -NHKNIVKLIEIVYDES--------------PTPKTDSTSPRPVGNYHGNNTANQQKLIT 154
+H NI+ L++++ E+ P+P P V + N
Sbjct: 68 GDHPNIISLLDVIRAENDRDIYLVFEFMGCPPSPPP----PTAVRTLSADTDLNA----- 118
Query: 155 GKHFFMILPYMVSDLTGLLHNPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANI 214
V GLL + V++I QLL ++H +HRD K +N+
Sbjct: 119 -----------VIRKGGLLQD-------VHVRSIFYQLLRATRFLHSGHVVHRDQKPSNV 160
Query: 215 LIDHKGVVKIADFGLARNYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYT 274
L+D VK+ DFGLAR+ P + T V TRWYRAPE++L YT
Sbjct: 161 LLDANCTVKLCDFGLARSLGDLPEGPE-------DQAVTEYVATRWYRAPEVLLSSHRYT 213
Query: 275 TAVDIWGIGCVFAEFFEKKPILQGQTDIDQGHVIFKLMGTPSMDE 319
VD+W +GC+ E +P+ G + + Q +I + + PS ++
Sbjct: 214 LGVDMWSLGCILGEMLRGRPLFPGTSTLHQLELILETIPPPSEED 258
>At2g23070 [TDK] KOG0668 Casein kinase II alpha subunit
Length = 432
Score = 115 bits (287), Expect = 3e-25
Identities = 98/348 (28%), Positives = 161/348 (46%), Gaps = 65/348 (18%)
Query: 53 NNYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRM-NH 111
++Y K+G+G + EVF+GIH N K IK + +K + +REI IL+ +
Sbjct: 130 DDYEVVRKVGRGKYSEVFEGIHATDNEKCVIKILKPVKKKKI-----KREIKILQNLCGG 184
Query: 112 KNIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTG 171
NIVKL++IV D+ KT S V N K F ++ P + SD
Sbjct: 185 PNIVKLLDIVRDQQS--KTPSLIFEHVNN---------------KDFKVLYPTL-SDY-- 224
Query: 172 LLHNPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKG-VVKIADFGLA 230
DV+ + +LL+ +++ H +HRD+K N++IDH+ +++ D+GLA
Sbjct: 225 ------------DVRYYIFELLKALDFCHSRGIMHRDVKPHNVMIDHEQRKLRLIDWGLA 272
Query: 231 RNYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFA-EF 289
Y+ G +Y V +R+++ PE+++ + Y ++D+W +GC+FA
Sbjct: 273 EFYH-------------PGKEYNVRVASRYFKGPELLVDLQDYDYSLDLWSLGCMFAGMI 319
Query: 290 FEKKPILQGQTDIDQGHVIFKLMGTPSMDEWGLAYH---------LPGSELTKTNYKSTL 340
F K+P G + DQ I K++GT ++ + Y L G K K
Sbjct: 320 FRKEPFFYGHDNYDQLVKIAKVLGTDELNAYLNKYRIELDPNLTSLVGRHSRKPWTKFIN 379
Query: 341 QERFSKALNETGXXXXXXXXXXDPYKRVTAMKAKKHPFFFEEPLPNAQ 388
E A+ E D +R TA +A HP+F+ P+ NA+
Sbjct: 380 SENQHLAVPE-AVDFVDKLLRYDHQERPTAKEAMAHPYFY--PIRNAE 424
>CE27220 [T] KOG0660 Mitogen-activated protein kinase
Length = 472
Score = 114 bits (286), Expect = 4e-25
Identities = 73/282 (25%), Positives = 130/282 (45%), Gaps = 30/282 (10%)
Query: 37 VQSRENEKVYGVTKFLNNYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFP 96
++ R+ + + + + Y + +G G FG V + + +N+KVAIK++ +
Sbjct: 64 LKKRQLQHDFKLERAAETYEPTQNIGSGAFGIVCEAVETSSNQKVAIKKVAHASATPTLA 123
Query: 97 ITAQREITILKRMNHKNIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGK 156
REI +L+ +NH NIV L +I + P G
Sbjct: 124 RRTLREIRVLRYINHPNIVPLRDIFRTKGPL---------------------------GI 156
Query: 157 HFFMILPYMVSDLTGLLHNPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILI 216
F+++ M ++L +++ + + QLL G+ Y+H HRD+K +N+L+
Sbjct: 157 DVFLVMDLMQNNLHHIIYGNEDPLEEHYINAFLGQLLRGLEYLHAACIAHRDLKPSNLLV 216
Query: 217 DHKGVVKIADFGLARNYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTA 276
+ G ++IADFG+A+ S K T V T YRAPE++ ++TA
Sbjct: 217 NQDGTLRIADFGMAKCADNSS---KKHDDEEHCYYMTQHVATLPYRAPELLFVLPEHSTA 273
Query: 277 VDIWGIGCVFAEFFEKKPILQGQTDIDQGHVIFKLMGTPSMD 318
VD+W +GC+F E + IL G++ Q ++ ++G P +
Sbjct: 274 VDMWAVGCIFGEMVIRNEILPGRSVQGQIKMLLTMLGQPPQE 315
>Hs20986499 [T] KOG0660 Mitogen-activated protein kinase
Length = 677
Score = 114 bits (285), Expect = 5e-25
Identities = 66/220 (30%), Positives = 107/220 (48%), Gaps = 19/220 (8%)
Query: 165 MVSDLTGLLHNPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKI 224
M SDL ++H+ + + V+ + QLL G+ Y+H + +HRD+K +N+L++ +KI
Sbjct: 1 MESDLHQIIHSSQ-PLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKI 59
Query: 225 ADFGLARNYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGC 284
DFG+AR SP +Y T V TRWYRAPE++L YT A+D+W +GC
Sbjct: 60 GDFGMARGLCTSPAEHQY--------FMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGC 111
Query: 285 VFAEFFEKKPILQGQTDIDQGHVIFKLMGTPSMDEWGLAYHLPGSELTKTNYKS------ 338
+F E ++ + G+ + Q +I ++GTPS G+E + +S
Sbjct: 112 IFGEMLARRQLFPGKNYVHQLQLIMMVLGTPS----PAVIQAVGAERVRAYIQSLPPRQP 167
Query: 339 TLQERFSKALNETGXXXXXXXXXXDPYKRVTAMKAKKHPF 378
E + +P R++A A +HPF
Sbjct: 168 VPWETVYPGADRQALSLLGRMLRFEPSARISAAAALRHPF 207
>At1g73670 [T] KOG0660 Mitogen-activated protein kinase
Length = 576
Score = 113 bits (282), Expect = 1e-24
Identities = 86/304 (28%), Positives = 134/304 (43%), Gaps = 57/304 (18%)
Query: 28 DKTGLEYIQVQSRE----------NEKVYGVTKFLNNYREEEKLGQGTFGEVFKGIHLGT 77
D + L I+VQ R N + + N Y+ +E +G+G++G V I T
Sbjct: 53 DPSKLRQIKVQQRNHLPMEKKGIPNAEFFTEYGEANRYQIQEVVGKGSYGVVGSAIDTHT 112
Query: 78 NRKVAIKRILVRAEKDLFPITAQ-----REITILKRMNHKNIVKLIEIVYDESPTPKTDS 132
+VAIK+I D+F + REI +L+ + H ++V++ I+ S D
Sbjct: 113 GERVAIKKI-----NDVFDHISDATRILREIKLLRLLLHPDVVEIKHIMLPPSRREFRD- 166
Query: 133 TSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGLLHNPRVEFGMADVKNIMLQL 192
+++ M SDL ++ + + + QL
Sbjct: 167 -------------------------VYVVFELMESDLHQVI-KANDDLTPEHHQFFLYQL 200
Query: 193 LEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLARNYYGSPPNLKYPGGAGSGAKY 252
L G+ Y+H HRD+K NIL + +KI DFGLAR + P + +
Sbjct: 201 LRGLKYVHAANVFHRDLKPKNILANADCKLKICDFGLARVSFNDAPTAIF---------W 251
Query: 253 TSVVVTRWYRAPEIVLG-DRHYTTAVDIWGIGCVFAEFFEKKPILQGQTDIDQGHVIFKL 311
T V TRWYRAPE+ YT A+DIW +GC+FAE KP+ G+ + Q ++
Sbjct: 252 TDYVATRWYRAPELCGSFFSKYTPAIDIWSVGCIFAEMLLGKPLFPGKNVVHQLDIMTDF 311
Query: 312 MGTP 315
+GTP
Sbjct: 312 LGTP 315
>SPBC8D2.19 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 559
Score = 112 bits (281), Expect = 1e-24
Identities = 88/312 (28%), Positives = 141/312 (44%), Gaps = 63/312 (20%)
Query: 42 NEKVYGVTK-----FLNNYREEEKLGQGTFGEVFKGIHLGTN---RKVAIKRILVRAE-K 92
NE +Y V F + Y ++KLG G+FG V+ N VA+K++ ++ K
Sbjct: 3 NESIYSVLDLTQVIFEDRYLVKQKLGDGSFGTVYLAQRKEKNGLYETVAVKKLKNSSKPK 62
Query: 93 DLFPITAQREITILKRMN-HKNIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQK 151
+ RE L++++ H ++ L+E D
Sbjct: 63 PKHELLKLRESLALRKISKHPCLIDLLETFMDPY-------------------------- 96
Query: 152 LITGKHFFMILPYMVSDLTGLLHNPRVE-FGMADVKNIMLQLLEGINYIHCNKFLHRDIK 210
++ F+++ +M +L L + F NI+LQ++ GI +IH + F+HRDIK
Sbjct: 97 ----RNIFLVMEFMDCNLFQLFKRRQGRLFTKETAFNILLQIISGIEHIHKHGFMHRDIK 152
Query: 211 TANIL--------IDHKGVVKIADFGLARNYYGSPPNLKYPGGAGSGAKYTSVVVTRWYR 262
NIL I + +K+ DFGLAR S P +Y V TRWYR
Sbjct: 153 PENILVKRISPKPISSRYSIKLGDFGLARPSVSSDPLTEY-------------VSTRWYR 199
Query: 263 APEIVLGDRHYTTAVDIWGIGCVFAEFFEKKPILQGQTDIDQGHVIFKLMGTPSMDEWG- 321
APE++L Y +VD++ GC+ E + KP+ G+ + DQ + + +++G P +DE
Sbjct: 200 APELLLRSGSYNHSVDLYAFGCIVFEIYSLKPLFPGRNETDQLNRVCEILGNPGIDELDT 259
Query: 322 LAYHLPGSELTK 333
L Y EL K
Sbjct: 260 LHYWSQAKELAK 271
>Hs20986521 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 427
Score = 112 bits (281), Expect = 1e-24
Identities = 76/264 (28%), Positives = 125/264 (46%), Gaps = 42/264 (15%)
Query: 52 LNNYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNH 111
L Y+ + +G G G V R VAIK++ + A RE+ ++K +NH
Sbjct: 23 LKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNH 82
Query: 112 KNIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTG 171
KNI+ L+ + TP Q+ L + ++++ M ++L
Sbjct: 83 KNIIGLLNVF-----TP--------------------QKSLEEFQDVYIVMELMDANLCQ 117
Query: 172 LLHNPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLAR 231
++ ++E + ++ Q+L GI ++H +HRD+K +NI++ +KI DFGLAR
Sbjct: 118 VI---QMELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLAR 174
Query: 232 NYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFE 291
AG+ T VVTR+YRAPE++LG Y VDIW +GC+ E +
Sbjct: 175 T-------------AGTSFMMTPYVVTRYYRAPEVILG-MGYKENVDIWSVGCIMGEMIK 220
Query: 292 KKPILQGQTDIDQGHVIFKLMGTP 315
+ G IDQ + + + +GTP
Sbjct: 221 GGVLFPGTDHIDQWNKVIEQLGTP 244
>Hs20986519 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 384
Score = 112 bits (281), Expect = 1e-24
Identities = 76/264 (28%), Positives = 125/264 (46%), Gaps = 42/264 (15%)
Query: 52 LNNYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNH 111
L Y+ + +G G G V R VAIK++ + A RE+ ++K +NH
Sbjct: 23 LKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNH 82
Query: 112 KNIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTG 171
KNI+ L+ + TP Q+ L + ++++ M ++L
Sbjct: 83 KNIIGLLNVF-----TP--------------------QKSLEEFQDVYIVMELMDANLCQ 117
Query: 172 LLHNPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLAR 231
++ ++E + ++ Q+L GI ++H +HRD+K +NI++ +KI DFGLAR
Sbjct: 118 VI---QMELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLAR 174
Query: 232 NYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFE 291
AG+ T VVTR+YRAPE++LG Y VDIW +GC+ E +
Sbjct: 175 T-------------AGTSFMMTPYVVTRYYRAPEVILG-MGYKENVDIWSVGCIMGEMIK 220
Query: 292 KKPILQGQTDIDQGHVIFKLMGTP 315
+ G IDQ + + + +GTP
Sbjct: 221 GGVLFPGTDHIDQWNKVIEQLGTP 244
>At4g00720 [G] KOG0658 Glycogen synthase kinase-3
Length = 472
Score = 112 bits (281), Expect = 1e-24
Identities = 95/353 (26%), Positives = 149/353 (41%), Gaps = 54/353 (15%)
Query: 47 GVTKFLNNYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITIL 106
G K +Y + +G G+FG VF+ L T +VAIK++L RE+ I+
Sbjct: 130 GKPKQTISYMAQRVVGTGSFGVVFQAKCLETGEQVAIKKVLQDKRYK------NRELQIM 183
Query: 107 KRMNHKNIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMV 166
+ +H N+V+L + T D V Y K T + M + +
Sbjct: 184 RLQDHPNVVRLRHSFFS---TTDKDELYLNLVLEYVPETVYRASKHYTKMNQHMPIIF-- 238
Query: 167 SDLTGLLHNPRVEFGMADVKNIMLQLLEGINYIH-CNKFLHRDIKTANILIDHKG-VVKI 224
V+ Q+ +NY+H HRDIK N+L++ + +KI
Sbjct: 239 ------------------VQLYTYQICRALNYLHRVVGVCHRDIKPQNLLVNPQTHQLKI 280
Query: 225 ADFGLARNYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGC 284
DFG A+ PN+ Y + +R+YRAPE++ G YT A+D+W GC
Sbjct: 281 CDFGSAKMLVPGEPNISY-------------ICSRYYRAPELIFGATEYTNAIDMWSGGC 327
Query: 285 VFAEFFEKKPILQGQTDIDQGHVIFKLMGTPSMDEWGLAYHLPGSELTKTNYKS----TL 340
V AE +P+ G++ IDQ I K++GTP+ +E T+ +
Sbjct: 328 VMAELLLGQPLFPGESGIDQLVEIIKILGTPTREE----IRCMNPNYTEFKFPQIKAHPW 383
Query: 341 QERFSKALNETGXXXXXXXXXXDPYKRVTAMKAKKHPFFFEEPLPNAQLTLPN 393
+ F K + P R TA++A HPFF + L + ++LPN
Sbjct: 384 HKIFHKRMPPEAVDLVSRLLQYSPNLRCTALEACAHPFF--DDLRDPNVSLPN 434
>Hs4506095 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 384
Score = 112 bits (280), Expect = 2e-24
Identities = 76/264 (28%), Positives = 126/264 (46%), Gaps = 42/264 (15%)
Query: 52 LNNYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNH 111
L Y+ + +G G G V R VAIK++ + A RE+ ++K +NH
Sbjct: 23 LKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNH 82
Query: 112 KNIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTG 171
KNI+ L+ + TP Q+ L + ++++ M ++L
Sbjct: 83 KNIIGLLNVF-----TP--------------------QKSLEEFQDVYIVMELMDANLCQ 117
Query: 172 LLHNPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLAR 231
++ ++E + ++ Q+L GI ++H +HRD+K +NI++ +KI DFGLAR
Sbjct: 118 VI---QMELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLAR 174
Query: 232 NYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFE 291
AG+ T VVTR+YRAPE++LG Y VD+W +GC+ E
Sbjct: 175 T-------------AGTSFMMTPYVVTRYYRAPEVILG-MGYKENVDLWSVGCIMGEMVC 220
Query: 292 KKPILQGQTDIDQGHVIFKLMGTP 315
K + G+ IDQ + + + +GTP
Sbjct: 221 HKILFPGRDYIDQWNKVIEQLGTP 244
>Hs20986523 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 427
Score = 112 bits (280), Expect = 2e-24
Identities = 76/264 (28%), Positives = 126/264 (46%), Gaps = 42/264 (15%)
Query: 52 LNNYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNH 111
L Y+ + +G G G V R VAIK++ + A RE+ ++K +NH
Sbjct: 23 LKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNH 82
Query: 112 KNIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTG 171
KNI+ L+ + TP Q+ L + ++++ M ++L
Sbjct: 83 KNIIGLLNVF-----TP--------------------QKSLEEFQDVYIVMELMDANLCQ 117
Query: 172 LLHNPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLAR 231
++ ++E + ++ Q+L GI ++H +HRD+K +NI++ +KI DFGLAR
Sbjct: 118 VI---QMELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLAR 174
Query: 232 NYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFE 291
AG+ T VVTR+YRAPE++LG Y VD+W +GC+ E
Sbjct: 175 T-------------AGTSFMMTPYVVTRYYRAPEVILG-MGYKENVDLWSVGCIMGEMVC 220
Query: 292 KKPILQGQTDIDQGHVIFKLMGTP 315
K + G+ IDQ + + + +GTP
Sbjct: 221 HKILFPGRDYIDQWNKVIEQLGTP 244
>At1g09840 [G] KOG0658 Glycogen synthase kinase-3
Length = 421
Score = 112 bits (280), Expect = 2e-24
Identities = 97/345 (28%), Positives = 146/345 (42%), Gaps = 58/345 (16%)
Query: 54 NYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNHKN 113
+Y E +G G+FG VF+ T VAIK++L RE+ I++ ++H N
Sbjct: 82 SYISEHVVGTGSFGMVFQAKCRETGEVVAIKKVLQDKRYK------NRELQIMQMLDHPN 135
Query: 114 IVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGLL 173
V L + + T N++ + F+ P V+ +
Sbjct: 136 AVALKHSFF---------------------SRTDNEEVYLNLVLEFV--PETVNRVARSY 172
Query: 174 HNPRVEFGMADVKNIMLQLLEGINYIHCNKF--LHRDIKTANILID-HKGVVKIADFGLA 230
+ VK Q+ + YIH N F HRDIK N+L++ H +KI DFG A
Sbjct: 173 SRTNQLMPLIYVKLYTYQICRALAYIH-NSFGLCHRDIKPQNLLVNPHTHQLKICDFGSA 231
Query: 231 RNYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFF 290
+ PN+ Y + +R+YRAPE++ G YTTA+DIW GCV AE
Sbjct: 232 KVLVKGEPNVSY-------------ICSRYYRAPELIFGASEYTTAIDIWSTGCVMAELL 278
Query: 291 EKKPILQGQTDIDQGHVIFKLMGTPSMDEWGLAYHLPGSELTKTNYK------STLQERF 344
+P+ G++ +DQ I K++GTP+ +E + T +K + F
Sbjct: 279 LGQPLFPGESGVDQLVEIIKVLGTPTREE------IKCMNPNYTEFKFPQIKPHPWHKVF 332
Query: 345 SKALNETGXXXXXXXXXXDPYKRVTAMKAKKHPFFFEEPLPNAQL 389
K L P R TA++A HP F E PN +L
Sbjct: 333 QKRLPPEAVDLLCRFFQYSPNLRCTALEACIHPLFDELRDPNTRL 377
>Hs4503097 [TDK] KOG0668 Casein kinase II alpha subunit
Length = 350
Score = 111 bits (278), Expect = 3e-24
Identities = 84/339 (24%), Positives = 158/339 (45%), Gaps = 61/339 (17%)
Query: 53 NNYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNH- 111
++Y+ KLG+G + EVF+ I++ N +V +K + +K + +RE+ IL+ +
Sbjct: 38 DDYQLVRKLGRGKYSEVFEAINITNNERVVVKILKPVKKKKI-----KREVKILENLRGG 92
Query: 112 KNIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTG 171
NI+KLI+ V D P KT P V Y N Q
Sbjct: 93 TNIIKLIDTVKD--PVSKT----PALVFEYINNTDFKQ---------------------- 124
Query: 172 LLHNPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDH-KGVVKIADFGLA 230
L+ +F D++ M +LL+ ++Y H +HRD+K N++IDH + +++ D+GLA
Sbjct: 125 -LYQILTDF---DIRFYMYELLKALDYCHSKGIMHRDVKPHNVMIDHQQKKLRLIDWGLA 180
Query: 231 RNYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAE-F 289
Y+ +Y V +R+++ PE+++ + Y ++D+W +GC+ A
Sbjct: 181 EFYH-------------PAQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMI 227
Query: 290 FEKKPILQGQTDIDQGHVIFKLMGTPSMDEWGLAYHLP--------GSELTKTNYKSTLQ 341
F ++P GQ + DQ I K++GT + + YH+ + ++ +++ +
Sbjct: 228 FRREPFFHGQDNYDQLVRIAKVLGTEELYGYLKKYHIDLDPHFNDILGQHSRKRWENFIH 287
Query: 342 ERFSKALNETGXXXXXXXXXXDPYKRVTAMKAKKHPFFF 380
++ D +R+TA +A +HP+F+
Sbjct: 288 SENRHLVSPEALDLLDKLLRYDHQQRLTAKEAMEHPYFY 326
>CE29466 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 390
Score = 110 bits (276), Expect = 5e-24
Identities = 74/255 (29%), Positives = 122/255 (47%), Gaps = 39/255 (15%)
Query: 61 LGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNHKNIVKLIEI 120
L G G V L T ++VAIK++ + A RE +L + H NI++L+
Sbjct: 44 LNAGAQGTVVMADDLVTTQRVAIKKMQQPFVMTMSAKRAYREFILLTTIKHPNIIRLLNA 103
Query: 121 VYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGLLHNPRVEF 180
TP T L T + ++++ M +L ++H R++
Sbjct: 104 F-----TPDTS--------------------LSTFREVYLVMELMTHNLHEVIHRLRLDH 138
Query: 181 GMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLARNYYGSPPNL 240
+ + Q L I ++H + +HRD+K +NI+++ + V+K+ DFGLAR
Sbjct: 139 --KTLSFFVYQSLCAIKHLHNSGVIHRDLKPSNIVVNDRCVLKVLDFGLARKK------- 189
Query: 241 KYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFEKKPILQGQT 300
+ + + VVTR+YRAPE++LG Y+ VDIW +GC+FAE + G+
Sbjct: 190 ----NVDTSMRMSDYVVTRYYRAPEVILG-LPYSEKVDIWSVGCIFAEMINHTVLFPGKD 244
Query: 301 DIDQGHVIFKLMGTP 315
IDQ I+ ++GTP
Sbjct: 245 RIDQWTKIYSVLGTP 259
>Hs4503095 [TDK] KOG0668 Casein kinase II alpha subunit
Length = 391
Score = 110 bits (275), Expect = 7e-24
Identities = 97/402 (24%), Positives = 179/402 (44%), Gaps = 63/402 (15%)
Query: 53 NNYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRM-NH 111
++Y+ KLG+G + EVF+ I++ N KV +K + +K + +REI IL+ +
Sbjct: 37 DDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKI-----KREIKILENLRGG 91
Query: 112 KNIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTG 171
NI+ L +IV D P +T + + H NNT +Q
Sbjct: 92 PNIITLADIVKD--PVSRTPA-----LVFEHVNNTDFKQ--------------------- 123
Query: 172 LLHNPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHK-GVVKIADFGLA 230
L+ ++ D++ M ++L+ ++Y H +HRD+K N++IDH+ +++ D+GLA
Sbjct: 124 -LYQTLTDY---DIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLA 179
Query: 231 RNYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAE-F 289
Y+ G +Y V +R+++ PE+++ + Y ++D+W +GC+ A
Sbjct: 180 EFYH-------------PGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMI 226
Query: 290 FEKKPILQGQTDIDQGHVIFKLMGTPSMDEWGLAYHL---PGSELTKTNYKSTLQERFSK 346
F K+P G + DQ I K++GT + ++ Y++ P + ERF
Sbjct: 227 FRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVH 286
Query: 347 ALNE-----TGXXXXXXXXXXDPYKRVTAMKAKKHPFFFEEPLPNAQLTLPNEECHESDI 401
+ N+ D R+TA +A +HP+F+ A++ + + +
Sbjct: 287 SENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTVVKDQARMGSSSMPGGSTPV 346
Query: 402 KRYKSEMNESMSQRPPSAPTGHTSTDNSIRAVTGAAFPKEAS 443
+ M +S P +P G + I A P A+
Sbjct: 347 S--SANMMSGISSVPTPSPLGPLAGSPVIAAANPLGMPVPAA 386
>At5g14640 [G] KOG0658 Glycogen synthase kinase-3
Length = 408
Score = 110 bits (275), Expect = 7e-24
Identities = 82/275 (29%), Positives = 123/275 (43%), Gaps = 44/275 (16%)
Query: 47 GVTKFLNNYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITIL 106
G K +Y E +GQG+FG VF+ L T VAIK++L RE+ +
Sbjct: 66 GQPKQTISYMAERIVGQGSFGIVFQAKCLETGETVAIKKVLQDKRYK------NRELQTM 119
Query: 107 KRMNHKNIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMV 166
+ ++H N+V L + T + D V Y K + + M + Y
Sbjct: 120 RLLDHPNVVSLKHCFFS---TTEKDELYLNLVLEYVPETVYRVSKHYSRANQRMPIIY-- 174
Query: 167 SDLTGLLHNPRVEFGMADVKNIMLQLLEGINYIHCNKFL-HRDIKTANILID-HKGVVKI 224
VK Q+ + YIH + HRDIK N+L++ H VK+
Sbjct: 175 ------------------VKLYTYQICRALAYIHGGVGVCHRDIKPQNLLVNPHTHQVKL 216
Query: 225 ADFGLARNYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGC 284
DFG A+ PN+ Y + +R+YRAPE++ G YTT +DIW GC
Sbjct: 217 CDFGSAKVLVKGEPNISY-------------ICSRYYRAPELIFGATEYTTTIDIWSAGC 263
Query: 285 VFAEFFEKKPILQGQTDIDQGHVIFKLMGTPSMDE 319
V AE +P+ G++ +DQ I K++GTP+ +E
Sbjct: 264 VLAELLLGQPLFPGESGVDQLVEIIKVLGTPTREE 298
>At3g50000 [TDK] KOG0668 Casein kinase II alpha subunit
Length = 333
Score = 110 bits (274), Expect = 9e-24
Identities = 86/339 (25%), Positives = 157/339 (45%), Gaps = 63/339 (18%)
Query: 53 NNYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRM-NH 111
++Y K+G+G + EVF+GI++ N K IK + +K + +REI IL+ +
Sbjct: 32 DDYEVVRKVGRGKYSEVFEGINMNNNEKCIIKILKPVKKKKI-----RREIKILQNLCGG 86
Query: 112 KNIVKLIEIVYDE-SPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLT 170
NIVKL+++V D+ S TP +I Y+ S
Sbjct: 87 PNIVKLLDVVRDQHSKTPS------------------------------LIFEYVNSTDF 116
Query: 171 GLLHNPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHK-GVVKIADFGL 229
+L+ ++ D++ + +LL+ +++ H +HRD+K N++IDH+ +++ D+GL
Sbjct: 117 KVLYPTLTDY---DIRYYIYELLKALDFCHSQGIMHRDVKPHNVMIDHELRKLRLIDWGL 173
Query: 230 ARNYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFA-E 288
A Y+ G +Y V +R+++ PE+++ + Y ++D+W +GC+FA
Sbjct: 174 AEFYH-------------PGKEYNVRVASRYFKGPELLVDLQDYDYSLDMWSLGCMFAGM 220
Query: 289 FFEKKPILQGQTDIDQGHVIFKLMGTPSMDEWGLAYHLPGSELTKTNYKSTLQERFSKAL 348
F K+P G + DQ I K++GT ++ + Y L + ++ +SK +
Sbjct: 221 IFRKEPFFYGHDNQDQLVKIAKVLGTDELNAYLNKYQLELDTQLEALVGRHSRKPWSKFI 280
Query: 349 NETGXXXXX--------XXXXXDPYKRVTAMKAKKHPFF 379
N D R+TA +A HP+F
Sbjct: 281 NADNRHLVSPEAIDYLDKLLRYDHQDRLTAKEAMAHPYF 319
>At2g01450 [T] KOG0660 Mitogen-activated protein kinase
Length = 516
Score = 110 bits (274), Expect = 9e-24
Identities = 80/267 (29%), Positives = 126/267 (46%), Gaps = 41/267 (15%)
Query: 53 NNYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNHK 112
+ Y+ +E +G+G++G V T KVAIK++ E I REI +L+ + H
Sbjct: 14 SQYQIQEVVGKGSYGVVASAECPHTGGKVAIKKMTNVFEHVSDAIRILREIKLLRLLRHP 73
Query: 113 NIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGL 172
+IV++ I+ P K K +++ M SDL +
Sbjct: 74 DIVEIKHIMLP--PCRKEF------------------------KDIYVVFELMESDLHHV 107
Query: 173 LHNPRVEFGMADVKN--IMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLA 230
L +V + + + QLL G+ ++H HRD+K NIL + +KI D GLA
Sbjct: 108 L---KVNDDLTPQHHQFFLYQLLRGLKFMHSAHVFHRDLKPKNILANADCKIKICDLGLA 164
Query: 231 RNYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGD-RHYTTAVDIWGIGCVFAEF 289
R + P+ + +T V TRWYRAPE+ +YT A+D+W +GC+FAE
Sbjct: 165 RVSFTDSPSAVF---------WTDYVATRWYRAPELCGSFYSNYTPAIDMWSVGCIFAEM 215
Query: 290 FEKKPILQGQTDIDQGHVIFKLMGTPS 316
KP+ G+ + Q ++ L+GTPS
Sbjct: 216 LTGKPLFPGKNVVHQLELVTDLLGTPS 242
>At2g23080 [TDK] KOG0668 Casein kinase II alpha subunit
Length = 333
Score = 109 bits (273), Expect = 1e-23
Identities = 86/338 (25%), Positives = 152/338 (44%), Gaps = 61/338 (18%)
Query: 53 NNYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRM-NH 111
++Y K+G+G + EVF+G ++ TN + IK + +K + +REI IL+ +
Sbjct: 32 DDYEVVRKVGRGKYSEVFEGKNVNTNERCVIKILKPVKKKKI-----KREIKILQNLCGG 86
Query: 112 KNIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTG 171
NIVKL +IV DE H + + + F ++ P +
Sbjct: 87 PNIVKLYDIVRDE-----------------HSKTPSLVFEFVNSVDFKVLYPTLTD---- 125
Query: 172 LLHNPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHK-GVVKIADFGLA 230
D++ + +LL+ +++ H +HRD+K N++IDH+ +++ D+GLA
Sbjct: 126 -----------YDIRYYIYELLKALDFCHSQGIMHRDVKPHNVMIDHQLRKLRLIDWGLA 174
Query: 231 RNYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFA-EF 289
Y+ G +Y V +R+++ PE+++ + Y ++D+W +GC+FA
Sbjct: 175 EFYH-------------PGKEYNVRVASRYFKGPELLVDLQDYDYSLDMWSLGCMFAGMI 221
Query: 290 FEKKPILQGQTDIDQGHVIFKLMGTPSMDEWGLAYHL---PGSELTKTNYKSTLQERFSK 346
F K+P G + DQ I K++GT +D + Y L P E + +F
Sbjct: 222 FRKEPFFYGHDNHDQLVKIAKVLGTNELDHYLNKYQLDLDPQLEALVGRHVPKPWSKFIN 281
Query: 347 ALNE-----TGXXXXXXXXXXDPYKRVTAMKAKKHPFF 379
A N+ D R+TA +A HP+F
Sbjct: 282 ADNQHLVSPEAIDFLDKLLQYDHQDRLTAREAMDHPYF 319
>7297631 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 372
Score = 108 bits (271), Expect = 2e-23
Identities = 76/264 (28%), Positives = 122/264 (45%), Gaps = 42/264 (15%)
Query: 53 NNYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNHK 112
+ Y +G G G V T + VAIK++ + A RE ++K +NHK
Sbjct: 22 SRYINLRPIGSGAQGIVCAAYDTITQQNVAIKKLSRPFQNVTHAKRAYREFKLMKLVNHK 81
Query: 113 NIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGL 172
NI+ L+ N Q+ L + ++++ M ++L +
Sbjct: 82 NIIGLL-------------------------NAFTPQRNLEEFQDVYLVMELMDANLCQV 116
Query: 173 LHNPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLARN 232
+ +++ + ++ Q+L GI ++H +HRD+K +NI++ +KI DFGLAR
Sbjct: 117 I---QMDLDHDRMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKADCTLKILDFGLART 173
Query: 233 YYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFEK 292
AG+ T VVTR+YRAPE++LG YT VDIW +GC+ E
Sbjct: 174 -------------AGTTFMMTPYVVTRYYRAPEVILG-MGYTENVDIWSVGCIMGEMIRG 219
Query: 293 KPILQGQTDIDQGHVIFKLMGTPS 316
+ G IDQ + I + +GTPS
Sbjct: 220 GVLFPGTDHIDQWNKIIEQLGTPS 243
>CE27574 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 463
Score = 107 bits (268), Expect = 4e-23
Identities = 92/368 (25%), Positives = 154/368 (41%), Gaps = 60/368 (16%)
Query: 52 LNNYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNH 111
L Y+ +G G G V N +VAIK++ + A RE+ ++ +NH
Sbjct: 116 LKRYQNLRLIGSGAQGIVCSAFDTVRNEQVAIKKLSRPFQNVTHAKRAYRELKLMSLVNH 175
Query: 112 KNIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTG 171
KNI+ ++ TP Q+KL ++++ M ++L
Sbjct: 176 KNIIGILNCF-----TP--------------------QKKLDEFNDLYIVMELMDANLCQ 210
Query: 172 LLHNPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLAR 231
++ +++ + ++ Q+L GI ++H +HRD+K +NI++ +KI DFGLAR
Sbjct: 211 VI---QMDLDHERLSYLLYQMLCGIRHLHSAGIIHRDLKPSNIVVRSDCTLKILDFGLAR 267
Query: 232 NYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFE 291
A T VVTR+YRAPE++LG Y VD+W IGC+F E
Sbjct: 268 T-------------AIEAFMMTPYVVTRYYRAPEVILG-MGYKENVDVWSIGCIFGELIR 313
Query: 292 KKPILQGQTDIDQGHVIFKLMGTPSMD-------------EWGLAYHLPGSELTKTNYKS 338
+ + G IDQ I + +GTP E Y E+ ++
Sbjct: 314 GRVLFPGGDHIDQWTRIIEQLGTPDRSFLERLQPTVRNYVENRPRYQATPFEVLFSDNMF 373
Query: 339 TLQERFSKALNETGXXXXXXXXXXDPYKRVTAMKAKKHPF---FFEEPLPNAQLTLPNEE 395
+ S+ DP +R++ A +HP+ +F+E A LP +
Sbjct: 374 PMTADSSRLTGAQARDLLSRMLVIDPERRISVDDALRHPYVNVWFDEIEVYAPPPLPYD- 432
Query: 396 CHESDIKR 403
H D+++
Sbjct: 433 -HNMDVEQ 439
>ECU07g1270 [G] KOG0658 Glycogen synthase kinase-3
Length = 334
Score = 107 bits (266), Expect = 7e-23
Identities = 82/269 (30%), Positives = 126/269 (46%), Gaps = 49/269 (18%)
Query: 55 YREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNHKNI 114
YR E +G+G+FG V K I + A+KR+ RE+ IL ++H NI
Sbjct: 56 YRYVEMIGRGSFGVVVK-IMDDRHNFFALKRVYQDRRYH------NRELGILMEVDHPNI 108
Query: 115 VKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGLLH 174
V+L+ + TD TS +G + +I ++ +L +
Sbjct: 109 VRLVSYFH-------TDKTS-------------------SGAYLNIITDFVGMNLEEYIK 142
Query: 175 -NPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLARNY 233
N VE +++++ Q+LEG+ Y+H HRD+K +NILID G+VKI D G A+
Sbjct: 143 ANRGVE--TEEIRSVYRQILEGLRYLHEKNICHRDMKPSNILIDTNGLVKICDLGSAKVI 200
Query: 234 YGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFEKK 293
N+ Y + +R+YRAPE +L + Y +DIW +GCV AEF
Sbjct: 201 KSGERNITY-------------ICSRFYRAPENLLDYKEYDFKIDIWSVGCVIAEFRHPG 247
Query: 294 PILQGQTDIDQGHVIFKLMGTPSMDEWGL 322
PI +G T + I +++ S D GL
Sbjct: 248 PIFKGDTSGSTLNRILEIVRVTSDDLIGL 276
>7289745 [TDK] KOG0668 Casein kinase II alpha subunit
Length = 336
Score = 106 bits (264), Expect = 1e-22
Identities = 88/354 (24%), Positives = 162/354 (44%), Gaps = 63/354 (17%)
Query: 53 NNYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNH- 111
++Y+ KLG+G + EVF+ I++ T K +K + +K + +REI IL+ +
Sbjct: 35 DDYQLVRKLGRGKYSEVFEAINITTTEKCVVKILKPVKKKKI-----KREIKILENLRGG 89
Query: 112 KNIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTG 171
NI+ L+ +V D P +T + H NNT +Q
Sbjct: 90 TNIITLLAVVKD--PVSRTPALIFE-----HVNNTDFKQ--------------------- 121
Query: 172 LLHNPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKG-VVKIADFGLA 230
L+ ++ +++ + +LL+ ++Y H +HRD+K N++IDH+ +++ D+GLA
Sbjct: 122 -LYQTLTDY---EIRYYLFELLKALDYCHSMGIMHRDVKPHNVMIDHENRKLRLIDWGLA 177
Query: 231 RNYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAE-F 289
Y+ G +Y V +R+++ PE+++ + Y ++D+W +GC+ A
Sbjct: 178 EFYH-------------PGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMI 224
Query: 290 FEKKPILQGQTDIDQGHVIFKLMGTPSMDEWGLAYHL---PGSELTKTNYKSTLQERFSK 346
F K+P G + DQ I K++GT + + Y++ P + ERF
Sbjct: 225 FRKEPFFHGHDNYDQLVRIAKVLGTEELYAYLDKYNIDLDPRFHDILQRHSRKRWERFVH 284
Query: 347 ALNE-----TGXXXXXXXXXXDPYKRVTAMKAKKHPFFFEEPLPNAQLTLPNEE 395
+ N+ D R+TA +A HP+F P+ N Q+ N++
Sbjct: 285 SDNQHLVSPEALDFLDKLLRYDHVDRLTAREAMAHPYFL--PIVNGQMNPNNQQ 336
>At5g67380 [TDK] KOG0668 Casein kinase II alpha subunit
Length = 333
Score = 105 bits (263), Expect = 2e-22
Identities = 86/339 (25%), Positives = 156/339 (45%), Gaps = 63/339 (18%)
Query: 53 NNYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRM-NH 111
++Y K+G+G + EVF+GI++ + K IK + +K + +REI IL+ +
Sbjct: 32 DDYEVVRKVGRGKYSEVFEGINVNSKEKCIIKILKPVKKKKI-----RREIKILQNLCGG 86
Query: 112 KNIVKLIEIVYDE-SPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLT 170
NIVKL+++V D+ S TP +I Y+ S
Sbjct: 87 PNIVKLLDVVRDQHSKTPS------------------------------LIFEYVNSTDF 116
Query: 171 GLLHNPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHK-GVVKIADFGL 229
+L+ ++ D++ + +LL+ +++ H +HRD+K N++IDH+ +++ D+GL
Sbjct: 117 KVLYPTLTDY---DIRYYIYELLKALDFCHSQGIMHRDVKPHNVMIDHELRKLRLIDWGL 173
Query: 230 ARNYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFA-E 288
A Y+ G +Y V +R+++ PE+++ + Y ++D+W +GC+FA
Sbjct: 174 AEFYH-------------PGKEYNVRVASRYFKGPELLVDLQDYDYSLDMWSLGCMFAGM 220
Query: 289 FFEKKPILQGQTDIDQGHVIFKLMGTPSMDEWGLAYHL---PGSELTKTNYKSTLQERFS 345
F K+P G + DQ I K++GT ++ + Y L P E + +F
Sbjct: 221 IFRKEPFFYGHDNQDQLVKIAKVLGTDELNAYLNKYQLELDPQLEALVGRHSRKPWSKFI 280
Query: 346 KALNE-----TGXXXXXXXXXXDPYKRVTAMKAKKHPFF 379
A N+ D R+TA +A H +F
Sbjct: 281 NADNQHLVSPEAIDFLDKLLRYDHQDRLTAKEAMAHAYF 319
>SPAC23C11.11 [TDK] KOG0668 Casein kinase II alpha subunit
Length = 332
Score = 105 bits (261), Expect = 3e-22
Identities = 89/348 (25%), Positives = 154/348 (43%), Gaps = 61/348 (17%)
Query: 43 EKVYGVTKFLNNYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQRE 102
E + V + +NY K+G+G + EVF+G+++ N K IK + K + +RE
Sbjct: 31 ENMQEVFGYQDNYEIIRKVGRGKYSEVFEGLNVLNNSKCIIKVLKPVKYKKI-----KRE 85
Query: 103 ITILKRM-NHKNIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMI 161
I IL+ + NI+ L++IV D P KT S V N F
Sbjct: 86 IKILQNLAGGPNIISLLDIVRD--PESKTPSLIFEFVDNID----------------FRT 127
Query: 162 LPYMVSDLTGLLHNPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKG- 220
L +SD D++ +LL+ +++ H +HRD+K N++IDHK
Sbjct: 128 LYPTLSDY--------------DIRYYSYELLKALDFCHSRGIMHRDVKPHNVMIDHKKR 173
Query: 221 VVKIADFGLARNYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIW 280
+++ D+GLA Y+ +G +Y V +R+++ PE+++ R Y ++DIW
Sbjct: 174 KLRLIDWGLAEFYH-------------AGMEYNVRVASRYFKGPELLVDFREYDYSLDIW 220
Query: 281 GIGCVFAE-FFEKKPILQGQTDIDQGHVIFKLMGTPSMDEWGLAYHLP--------GSEL 331
G +FA F+K +G+ + DQ I K++GT + + Y + +
Sbjct: 221 SFGVMFAALIFKKDTFFRGRDNYDQLVKIAKVLGTDELFAYVQKYQIVLDRQYDNILGQY 280
Query: 332 TKTNYKSTLQERFSKALNETGXXXXXXXXXXDPYKRVTAMKAKKHPFF 379
K ++ S + N+ D +R+T +A HP+F
Sbjct: 281 PKRDWYSFVNRDNRSLANDEAIDLLNRLLRYDHQERLTCQEAMAHPYF 328
>YIL035c [TDK] KOG0668 Casein kinase II alpha subunit
Length = 372
Score = 104 bits (259), Expect = 5e-22
Identities = 91/358 (25%), Positives = 156/358 (43%), Gaps = 65/358 (18%)
Query: 54 NYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNHKN 113
+Y E K+G+G + EVF+G+ L + K+ IK +LK + K
Sbjct: 39 DYEIENKVGRGKYSEVFQGVKLDSKVKIVIK--------------------MLKPVKKKK 78
Query: 114 IVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGK-------------HFFM 160
I + I+I+ D S +T P Y+ N + K I H F
Sbjct: 79 IKREIKILTDLSNEKVPPTTLPFQKDQYYTNQKEDVLKFIRPYIFDQPHNGHANIIHLFD 138
Query: 161 ILPYMVSDLTGLLHN--PRVEFGMA-------DVKNIMLQLLEGINYIHCNKFLHRDIKT 211
I+ +S L+ V+F + +++ M +LL+ ++Y H +HRD+K
Sbjct: 139 IIKDPISKTPALVFEYVDNVDFRILYPKLTDLEIRFYMFELLKALDYCHSMGIMHRDVKP 198
Query: 212 ANILIDHKG-VVKIADFGLARNYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGD 270
N++IDHK +++ D+GLA Y+ +Y V +R+++ PE+++
Sbjct: 199 HNVMIDHKNKKLRLIDWGLAEFYH-------------VNMEYNVRVASRFFKGPELLVDY 245
Query: 271 RHYTTAVDIWGIGCVFAE-FFEKKPILQGQTDIDQGHVIFKLMGTPSMDEWGLAYH--LP 327
R Y ++D+W G + A F+++P G ++ DQ I K++GT +++ L Y LP
Sbjct: 246 RMYDYSLDLWSFGTMLASMIFKREPFFHGTSNTDQLVKIVKVLGTSDFEKYLLKYEITLP 305
Query: 328 GSELTKTNYKSTLQERF----SKAL--NETGXXXXXXXXXXDPYKRVTAMKAKKHPFF 379
Y RF +K L N+ D +R+TA +A HP+F
Sbjct: 306 REFYDMDQYIRKPWHRFINDGNKHLSGNDEIIDLIDNLLRYDHQERLTAKEAMGHPWF 363
>CE17321 [TDK] KOG0668 Casein kinase II alpha subunit
Length = 360
Score = 103 bits (257), Expect = 8e-22
Identities = 87/339 (25%), Positives = 155/339 (45%), Gaps = 61/339 (17%)
Query: 52 LNNYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNH 111
+++Y+ KLG+G + EVF+G + T+ KV +K + +K + +REI IL+ +
Sbjct: 35 IDDYQLVRKLGRGKYSEVFEGFKMSTDEKVVVKILKPVKKKKI-----KREIKILENLRG 89
Query: 112 -KNIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLT 170
NI+ L+++V D P +T + H NN+ +Q T +SD
Sbjct: 90 GTNIITLLDVVKD--PISRTPALIFE-----HVNNSDFKQLYQT-----------LSDY- 130
Query: 171 GLLHNPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILID-HKGVVKIADFGL 229
D++ + +LL+ +++ H +HRD+K N++ID K +++ D+GL
Sbjct: 131 -------------DIRYYLYELLKALDFCHSQGIMHRDVKPHNVMIDAEKRELRLIDWGL 177
Query: 230 ARNYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAE- 288
A Y+ Y V +R+++ PE+++ + Y ++D+W +GC+ A
Sbjct: 178 AEFYHPRQD-------------YNVRVASRYFKGPELLVDYQCYDYSLDMWSLGCMLASM 224
Query: 289 FFEKKPILQGQTDIDQGHVIFKLMGTPSMDEWGLAYHL---PGSELTKTNYKSTLQERFS 345
F K+P G + DQ I K++GT + E+ YH+ P + ERF
Sbjct: 225 IFRKEPFFHGHDNYDQLVRIAKVLGTDELYEYIARYHIDLDPRFNDILGRHSRKRWERFI 284
Query: 346 KALNE-----TGXXXXXXXXXXDPYKRVTAMKAKKHPFF 379
A N+ D +R+TA +A H +F
Sbjct: 285 HAENQHLVTPEALDFLDKLLRYDHAERLTAQEAMGHEYF 323
>SPAC9G1.02 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and related
serine/threonine protein kinases
Length = 1401
Score = 101 bits (252), Expect = 3e-21
Identities = 83/267 (31%), Positives = 123/267 (45%), Gaps = 55/267 (20%)
Query: 64 GTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQ--REITILKRMNHKNIVKLIEIV 121
G FG+V+ G+++ T +A+K I ++ + Q E+T+L+R+NH N+V
Sbjct: 1046 GMFGDVYTGVNMETGDLLAVKEIKLQDSRTFRSTVDQIHNEMTVLERLNHPNVV------ 1099
Query: 122 YDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGLLHNPRVEFG 181
Y+G ++ I FM L LL + R+E
Sbjct: 1100 ------------------TYYGVEVHREKVYI-----FMEF-CQGGSLADLLAHGRIEDE 1135
Query: 182 MADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLARNYYGSPPNLK 241
+K ++QLLEG+ YIH LHRDIK ANIL+DH+G++K +DFG A Y SPP
Sbjct: 1136 NV-LKVYVVQLLEGLAYIHSQHILHRDIKPANILLDHRGMIKYSDFGSA--LYVSPPTDP 1192
Query: 242 YPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYT-TAVDIWGIGCVFAEFFEKKPILQGQT 300
+ + T Y APEI+LG + A+DIW +GCV E ++ G T
Sbjct: 1193 EVRYEDIQPELQHLAGTPMYMAPEIILGTKKGDFGAMDIWSLGCVILE------MMTGST 1246
Query: 301 DIDQGHVIFKLMGTPSMD-EWGLAYHL 326
+ MD EW + YH+
Sbjct: 1247 PWSE------------MDNEWAIMYHV 1261
>At1g63700 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 883
Score = 101 bits (251), Expect = 4e-21
Identities = 66/245 (26%), Positives = 112/245 (44%), Gaps = 47/245 (19%)
Query: 53 NNYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQR---EITILKRM 109
+ +++ LG G+FG V+ G + + A+K + + ++ +AQ+ EI++L R+
Sbjct: 398 SRWKKGRLLGMGSFGHVYLGFNSESGEMCAMKEVTLCSDDPKSRESAQQLGQEISVLSRL 457
Query: 110 NHKNIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDL 169
H+NIV+ Y+G+ T + + ++ L Y+
Sbjct: 458 RHQNIVQ------------------------YYGSETVDDK-------LYIYLEYVSGGS 486
Query: 170 TGLLHNPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGL 229
L +FG ++N Q+L G+ Y+H +HRDIK ANIL+D G VK+ADFG+
Sbjct: 487 IYKLLQEYGQFGENAIRNYTQQILSGLAYLHAKNTVHRDIKGANILVDPHGRVKVADFGM 546
Query: 230 ARNYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEF 289
A++ L + G + ++ APE++ AVDIW +GC E
Sbjct: 547 AKHITAQSGPLSFKG-------------SPYWMAPEVIKNSNGSNLAVDIWSLGCTVLEM 593
Query: 290 FEKKP 294
KP
Sbjct: 594 ATTKP 598
>CE17305 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 375
Score = 100 bits (249), Expect = 7e-21
Identities = 85/361 (23%), Positives = 152/361 (41%), Gaps = 68/361 (18%)
Query: 61 LGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNHKNIVKLIEI 120
L G G V L T ++VAIK++ + A RE +L + H NI++L+
Sbjct: 35 LNVGAQGIVVMADDLVTTQRVAIKKMQQPFLLTMSARRAYREFILLTTLKHPNIIRLLNA 94
Query: 121 VYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGLLHNPRVEF 180
TP T +S + V ++++ +M +L ++H R++
Sbjct: 95 F-----TPDTSLSSFQEV--------------------YLVMEFMTHNLHEVIHRLRLDH 129
Query: 181 GMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLARNYYGSPPNL 240
+ ++ Q L I ++H F+HRD+K +NI+++ + V+K+ DFGLAR
Sbjct: 130 --ETLSFLVYQSLCAIKHLHNLGFIHRDLKPSNIVVNERCVLKVLDFGLARR-------- 179
Query: 241 KYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFEKKPILQGQT 300
+ + V TR+YRAPE++LG +Y+ VDIW +GC+ AE + G+
Sbjct: 180 -----RNVDMRMSDYVGTRYYRAPEVILG-LNYSEKVDIWSVGCILAEMINHTVLFPGKD 233
Query: 301 DIDQGHVIFKLMGTPSMDEWGLAYHLPGSELTKTNYKSTLQERFSKALNE---------- 350
DQ I ++ TP + + E Y +L + ++A NE
Sbjct: 234 IRDQWTQISSVLRTPD------DHFINQLEPIGAVYVRSLPQHLARAFNEIVPDSNFLPE 287
Query: 351 -----------TGXXXXXXXXXXDPYKRVTAMKAKKHPFFFEEPLPNAQLTLPNEECHES 399
+P +R + A HP+ ++ + +P++E ++
Sbjct: 288 TENPKDHLTLHMARDLLFNMLKINPEERYSVEDALNHPYTMDDEVNAPASEIPDDEVNDI 347
Query: 400 D 400
D
Sbjct: 348 D 348
>YJL106w [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 645
Score = 99.8 bits (247), Expect = 1e-20
Identities = 57/159 (35%), Positives = 81/159 (50%), Gaps = 30/159 (18%)
Query: 174 HNPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILI----------------- 216
H R F + +K+I+ Q+L G+ +IH + F HRD+K NILI
Sbjct: 159 HRRRRVFSIPSLKSILSQILAGLKHIHEHNFFHRDLKPENILITPSTQYFEKEYMNQIGY 218
Query: 217 DHKGVVKIADFGLARNYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTA 276
V+K+ADFGLAR+ P YT+ V TRWYR+PEI+L +Y+
Sbjct: 219 QDNYVIKLADFGLARHVENKNP-------------YTAYVSTRWYRSPEILLRSGYYSKP 265
Query: 277 VDIWGIGCVFAEFFEKKPILQGQTDIDQGHVIFKLMGTP 315
+DIW GCV E + + G +IDQ I +++GTP
Sbjct: 266 LDIWAFGCVAVEVTVFRALFPGANEIDQIWKILEVLGTP 304
>ECU05g1510 [TDK] KOG0668 Casein kinase II alpha subunit
Length = 319
Score = 99.0 bits (245), Expect = 2e-20
Identities = 70/288 (24%), Positives = 137/288 (47%), Gaps = 55/288 (19%)
Query: 42 NEKVYGVTK-FLNNYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQ 100
N + Y +T + Y+ +++G+G + EVF+G + ++I+++A K +
Sbjct: 23 NYECYTITTGSIEKYQIYQRMGRGKYSEVFEG-------RKDREKIVIKALKPVRKAKIC 75
Query: 101 REITILKRMNHKNIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFM 160
RE+ IL+ ++HKNI+KL+++V D + + +
Sbjct: 76 REVLILRNLSHKNIIKLMDVVVDPE-----------------------------SQIYSL 106
Query: 161 ILPYMVSDLTGLLHNPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDH-K 219
I Y+ + + + D+ Q+L ++Y H +HRDIK N++I+ +
Sbjct: 107 IFEYIEHEDYAKIFE---KLCYKDIVEYSRQILSALSYCHSMGIIHRDIKPQNMVINQAR 163
Query: 220 GVVKIADFGLARNYYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDI 279
+KI D+GLA Y+ +Y+ V +R+Y+ PE+++ +Y ++DI
Sbjct: 164 RELKIIDWGLAEFYHPKK-------------EYSVRVASRYYKGPELLVDYPYYDYSLDI 210
Query: 280 WGIGCVFAEF-FEKKPILQGQTDIDQGHVIFKLMGTPSMDEWGLAYHL 326
W GCV AE F+K+P G+++ DQ I +++G + ++ Y +
Sbjct: 211 WSFGCVLAELVFKKRPFFHGESNSDQLVKIARILGYTHLKKYVRKYKM 258
>CE29318 [T] KOG0660 Mitogen-activated protein kinase
Length = 474
Score = 98.2 bits (243), Expect = 3e-20
Identities = 93/342 (27%), Positives = 143/342 (41%), Gaps = 53/342 (15%)
Query: 59 EKLGQGTFGEVFKGIHL---GTNRKVAIKRILVRAEKDLFPITAQR---EITILKRMNHK 112
E LG G+FG V K + G R VAIK++ E P A+R E +L+ M H
Sbjct: 122 EYLGGGSFGNVIKTSAVCRDGLRRYVAIKKM---REPFFDPHHARRIFRETKLLQLMRHD 178
Query: 113 NIVKLIEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMVSDLTGL 172
NI+ ++I +P + D V + G+ + IL +
Sbjct: 179 NIICALDIY---TPDEENDFRDVYVVTEF------------AGRSLYQILKQQRDYGRRV 223
Query: 173 LHNPRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLARN 232
L + ++F I+ Q++ + YIH +HRD+K N+ + + I DFGLAR+
Sbjct: 224 LTDEHIKF-------IIYQIIRALKYIHSANIIHRDLKPGNLALTDDSDLMILDFGLARS 276
Query: 233 YYGSPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGD-RHYTTAVDIWGIGCVFAEFFE 291
+L T V TRWYR+PE++ YT D+W +GC+ AE
Sbjct: 277 LEKKDTSL------------TQYVQTRWYRSPEVIYWKIDSYTNLADMWSLGCIAAELLT 324
Query: 292 KKPILQGQTDIDQGHVIFKLMGTPSMDEWGLAYHLPGSELTK-------TNYKSTLQERF 344
+P+ G Q I +L G+P +E S K T+ + ++ F
Sbjct: 325 GEPLFPGDEPNAQYQRITQLCGSPD-EELLTKIENDNSSAIKAVIQSYTTHKRRNFRDVF 383
Query: 345 S-KALNETGXXXXXXXXXXDPYKRVTAMKAKKHPFFFEEPLP 385
S +E DP KR+T +A +HP+ E LP
Sbjct: 384 SAHNPSEDFIDLLEKLLVLDPEKRITVEEAIQHPYLAEFSLP 425
>Hs16306492 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 240
Score = 97.8 bits (242), Expect = 4e-20
Identities = 49/124 (39%), Positives = 67/124 (53%)
Query: 256 VVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFEKKPILQGQTDIDQGHVIFKLMGTP 315
VVT WYR+PE++LG Y+T VDIW IG +FAE KKP+ G ++IDQ IF+ +GTP
Sbjct: 107 VVTLWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTP 166
Query: 316 SMDEWGLAYHLPGSELTKTNYKSTLQERFSKALNETGXXXXXXXXXXDPYKRVTAMKAKK 375
+ + W L + T +K K L+E G DP KR++ A
Sbjct: 167 NNEVWPEVESLQDYKNTFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALN 226
Query: 376 HPFF 379
HP+F
Sbjct: 227 HPYF 230
Score = 67.4 bits (163), Expect = 6e-11
Identities = 31/74 (41%), Positives = 52/74 (69%)
Query: 52 LNNYREEEKLGQGTFGEVFKGIHLGTNRKVAIKRILVRAEKDLFPITAQREITILKRMNH 111
+ +Y + EK+G+GT+G V+KG H T + VA+K+I + +E++ P TA REI++LK + H
Sbjct: 1 MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRH 60
Query: 112 KNIVKLIEIVYDES 125
NIV L +++ +S
Sbjct: 61 PNIVSLQDVLMQDS 74
>Hs15011880 [T] KOG0201 Serine/threonine protein kinase
Length = 416
Score = 97.4 bits (241), Expect = 6e-20
Identities = 101/374 (27%), Positives = 160/374 (42%), Gaps = 85/374 (22%)
Query: 59 EKLGQGTFGEVFKGIHLGTNRKVAIKRI-LVRAEKDLFPITAQREITILKRMNHKNIVKL 117
E++G+G+FGEVFKGI T + VAIK I L AE ++ I Q+EIT+L + + + K
Sbjct: 28 ERIGKGSFGEVFKGIDNRTQQVVAIKIIDLEEAEDEIEDI--QQEITVLSQCDSSYVTK- 84
Query: 118 IEIVYDESPTPKTDSTSPRPVGNYHGNNTANQQKLITGKHFFMILPYMV--SDLTGLLHN 175
Y+G+ + G ++I+ Y+ S L L
Sbjct: 85 -----------------------YYGS-------YLKGSKLWIIMEYLGGGSALDLLRAG 114
Query: 176 PRVEFGMADVKNIMLQLLEGINYIHCNKFLHRDIKTANILIDHKGVVKIADFGLARNYYG 235
P EF +A ++ ++L+G++Y+H K +HRDIK AN+L+ +G VK+ADFG+A
Sbjct: 115 PFDEFQIA---TMLKEILKGLDYLHSEKKIHRDIKAANVLLSEQGDVKLADFGVAGQL-- 169
Query: 236 SPPNLKYPGGAGSGAKYTSVVVTRWYRAPEIVLGDRHYTTAVDIWGIGCVFAEFFEKKPI 295
+ K + V T ++ APE V+ Y + DIW +G E + +P
Sbjct: 170 ----------TDTQIKRNTFVGTPFWMAPE-VIQQSAYDSKADIWSLGITAIELAKGEP- 217
Query: 296 LQGQTDIDQGHVIFKLMGTPSMDEWGLAYHLPGSELTKTNYKSTLQERFSKALNETGXXX 355
+D+ V+F L N TL F+K+ E
Sbjct: 218 --PNSDMHPMRVLF---------------------LIPKNNPPTLVGDFTKSFKE----F 250
Query: 356 XXXXXXXDPYKRVTAMKAKKHPFFFEEPLPNAQLTLPNEECHESDIKRYKSEMNESMSQR 415
DP R TA + KH F + + LT + KR+K+E +
Sbjct: 251 IDACLNKDPSFRPTAKELLKHKFIVKNSKKTSYLTELIDR-----FKRWKAEGHSDDESD 305
Query: 416 PPSAPTGHTSTDNS 429
+ + TS +N+
Sbjct: 306 SEGSDSESTSRENN 319
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.314 0.134 0.398
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 41,975,380
Number of Sequences: 60738
Number of extensions: 2039054
Number of successful extensions: 10663
Number of sequences better than 1.0e-05: 1032
Number of HSP's better than 0.0 without gapping: 324
Number of HSP's successfully gapped in prelim test: 708
Number of HSP's that attempted gapping in prelim test: 8028
Number of HSP's gapped (non-prelim): 1923
length of query: 645
length of database: 30,389,216
effective HSP length: 113
effective length of query: 532
effective length of database: 23,525,822
effective search space: 12515737304
effective search space used: 12515737304
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)