ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIV2654 check: MH I KOG3719 Lipid transport and metabolism Carnitine O-acyltransferase CPT2/YAT1
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIV2654 908257 905663 -865
(865 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YER024w [I] KOG3719 Carnitine O-acyltransferase CPT2/YAT1 884 0.0
YAR035w [I] KOG3719 Carnitine O-acyltransferase CPT2/YAT1 209 2e-53
Hs4503023 [I] KOG3719 Carnitine O-acyltransferase CPT2/YAT1 130 7e-30
7292290 [I] KOG3719 Carnitine O-acyltransferase CPT2/YAT1 127 6e-29
YML042w [I] KOG3717 Carnitine O-acyltransferase CRAT 108 4e-23
CE12132 [I] KOG3716 Carnitine O-acyltransferase CPTI 99 2e-20
CE27752 [I] KOG3716 Carnitine O-acyltransferase CPTI 98 6e-20
Hs4758050 [I] KOG3716 Carnitine O-acyltransferase CPTI 97 8e-20
Hs4503021 [I] KOG3716 Carnitine O-acyltransferase CPTI 97 8e-20
CE14398 [I] KOG3716 Carnitine O-acyltransferase CPTI 97 8e-20
CE18907 [I] KOG3719 Carnitine O-acyltransferase CPT2/YAT1 95 4e-19
Hs21618334 [I] KOG3717 Carnitine O-acyltransferase CRAT 89 3e-17
Hs21618331 [I] KOG3717 Carnitine O-acyltransferase CRAT 89 3e-17
Hs20546734 [I] KOG3716 Carnitine O-acyltransferase CPTI 89 4e-17
CE28125 [I] KOG3716 Carnitine O-acyltransferase CPTI 87 1e-16
HsM4755132 [I] KOG3717 Carnitine O-acyltransferase CRAT 87 1e-16
HsM4557487 [I] KOG3717 Carnitine O-acyltransferase CRAT 87 1e-16
7303736 [I] KOG3716 Carnitine O-acyltransferase CPTI 87 1e-16
CE20086 [I] KOG3718 Carnitine O-acyltransferase CROT 84 9e-16
Hs11038620 [I] KOG3717 Carnitine O-acyltransferase CRAT 82 3e-15
Hs10181098 [I] KOG3717 Carnitine O-acyltransferase CRAT 82 3e-15
CE03306 [I] KOG3718 Carnitine O-acyltransferase CROT 82 4e-15
7300431 [I] KOG3717 Carnitine O-acyltransferase CRAT 79 4e-14
Hs10863953 [I] KOG3718 Carnitine O-acyltransferase CROT 75 4e-13
CE21255 [I] KOG3716 Carnitine O-acyltransferase CPTI 75 6e-13
7298923 [I] KOG3717 Carnitine O-acyltransferase CRAT 70 1e-11
CE17308 [I] KOG3717 Carnitine O-acyltransferase CRAT 68 5e-11
7301624 [I] KOG3718 Carnitine O-acyltransferase CROT 65 3e-10
CE25326 [I] KOG3716 Carnitine O-acyltransferase CPTI 65 6e-10
Hs21618336 [I] KOG3717 Carnitine O-acyltransferase CRAT 60 2e-08
7298001 [I] KOG3717 Carnitine O-acyltransferase CRAT 57 1e-07
>YER024w [I] KOG3719 Carnitine O-acyltransferase CPT2/YAT1
Length = 923
Score = 884 bits (2285), Expect = 0.0
Identities = 486/942 (51%), Positives = 623/942 (65%), Gaps = 120/942 (12%)
Query: 5 TFINEKNLPKLPLPDLQKTLEEMEDSLKPLYYADGYYKHPLHPEESSELHENIEKFLHSN 64
TF +E+ LPKLPLP L TL+ +++SL+PLYYADGYY+HPL PE+ +L I F +
Sbjct: 16 TFKHEEELPKLPLPKLCDTLQRLKESLEPLYYADGYYQHPLDPEQIEKLSSIIRDFEENP 75
Query: 65 AAVKLQEKLKMFDRFNGCYLDKLHLDINNHTSTKEIQDDVLPRNPFLILAEDATSDISQA 124
+ KLQ KL+ + CYLD+LHLDINN TST+EIQDDVLPRNPFL+LA+DA +I+QA
Sbjct: 76 VSEKLQSKLQSYHDTRDCYLDELHLDINNQTSTREIQDDVLPRNPFLVLADDALPNITQA 135
Query: 125 VRSGVLCSSALRFVSALRQNHLPPDCGS-DGKPMSMLPYTNLFGTTRCPVFEHGEVESFD 183
RS VL SA RF+SAL+Q+ LPPD + +GKP+SM P+ NLFGTTR PVF+ GEVE+FD
Sbjct: 136 DRSAVLVHSAARFISALKQDLLPPDINATNGKPLSMAPFLNLFGTTRSPVFQRGEVENFD 195
Query: 184 LNRPYDESDLEAELNNLSAQRRPSTASSEASN-QPSANSDDDL------EFFNVHGITKK 236
LN+PY SDLE P +S E N +P+ DD + F +GIT K
Sbjct: 196 LNKPYTASDLED----------PDYSSDEDDNDEPTQKDFDDRKRKHEEDIFTGNGITIK 245
Query: 237 QYPDSKHIMIISKGQYYTLEVLDENDNALFTDSQLSRVFQHIIDDSTTSYSLKRATALGS 296
++PDSKHI+IIS+GQYYTLEVLD + ++T ++L+ +F HII DS+ ++++TALGS
Sbjct: 246 RHPDSKHILIISRGQYYTLEVLDSTNKIIYTAAELTTIFNHIIKDSS---GIEKSTALGS 302
Query: 297 LTSYSFKNWKYARKRLQKRYPQELNVIDSALFIVVLDESTS--------TSDINE----- 343
LTS+SF+NWKYARKRLQKRYP EL+ IDSALF++VLDES T+DI++
Sbjct: 303 LTSHSFRNWKYARKRLQKRYPNELHRIDSALFVLVLDESQEETTNDGDDTADISQMFNRT 362
Query: 344 -----------DCKRLYYGTSIVDDVTGFQVGSCTSRWYDKLQLVVTADSKAAVIWDSFT 392
+CKR++YGTSI++ G QVGSC SRWYDKLQLVVTAD+KA VIWDSFT
Sbjct: 363 ITERDKKCTSANCKRVFYGTSIINS-KGHQVGSCVSRWYDKLQLVVTADAKATVIWDSFT 421
Query: 393 CDGSVVLRFTSDIYAESILRLAREVHAGDPHFSLWPQVPKAS--SKDAWTEKFS------ 444
CDGSVVLRFTS+IY ES+LRLAR+V+AGDP FSLWP V + +K T S
Sbjct: 422 CDGSVVLRFTSEIYTESVLRLARDVNAGDPQFSLWPNVTQMDPETKKLMTATISADGGGP 481
Query: 445 ----------KITWSFSHILNTHVHLSETKLTDLISKHDIVHTTIPFGRRTAQKLGVRAD 494
KI WSFS+ILNTHVHLSETKL DLISK+DIV +IP GRR+AQ+LGV+ D
Sbjct: 482 SEIDPKLVVNKIDWSFSNILNTHVHLSETKLADLISKYDIVRASIPLGRRSAQRLGVKPD 541
Query: 495 SLIQIALQIAHYALYGKMVFSFEPVSTRFFQNSRSTFIPIQTQELLELCQLFISNSLNET 554
S++Q+ALQIAHYALYG+MVF EPVSTR F+NSRS+FI IQ+Q LLELCQLFIS+S++ T
Sbjct: 542 SMVQVALQIAHYALYGRMVFGLEPVSTRGFKNSRSSFINIQSQALLELCQLFISSSIDGT 601
Query: 555 GKLEKFITACNDHSERIQKAQRGTGFEKHFNAIKYLFKFHDHFDIGLSPEEFEISSKVFN 614
KL+KFI C H+ ++ A+ G G+EKHFNA+KYLFKFHDHF I LS +E + +F
Sbjct: 602 DKLDKFIQTCETHNNMVKHAKSGVGYEKHFNALKYLFKFHDHFGIHLSGDESSAAKDLFE 661
Query: 615 DAMLEPFSAPELIASNCGNSAMTAFGVTPAVPQGFGIGYIIKNEQCDITLTSQYRQGRRL 674
+ ++ PFS PELI +NCGN+A T FG+TPAVP GFGIGYIIK++Q D+T+TSQ+RQG RL
Sbjct: 662 NPLVLPFSQPELIVANCGNAATTTFGITPAVPHGFGIGYIIKDDQVDLTVTSQFRQGDRL 721
Query: 675 AFMLKWVLTEINNYWELXXXXXXXXXX-----XXDQLYEIDNAINQLKFNSLSTKPEIAK 729
FML WVL EI +YW + D+LYE+DNA+N
Sbjct: 722 MFMLSWVLGEIRSYWRMSRGTSHNKTGVKISPVVDKLYEMDNAVN--------------N 767
Query: 730 SPVQFAERPNLGXXXXXXXXXIFNGGHGFLELKGHLESRASSRPISRSGSNLKLSAMNTT 789
P + N N GF +L+GH++SR S+ + S NL+ T
Sbjct: 768 PPKRNGHTVNGSRKTSSSSQVNLNRYGGFFDLEGHIDSRNISK--TPSMKNLQ----KTF 821
Query: 790 NSLQPTLSNGLEDALTSTISITSEVLKQNAGHEILKIDASNIG--------ETQPQV--- 838
N L + N D +S +S+ +E K N GHEIL+I + ET ++
Sbjct: 822 NGLTMSADN---DHSSSAVSVPTEKEKLNTGHEILQIQPREVASNGLEADDETDIEIVAG 878
Query: 839 -----------------QKKNVVSSKFEINFDRSSVGRKVNT 863
+K+NV++S+F+I+FDRS VGRKV T
Sbjct: 879 NADGTSSSASSATSLNSKKRNVINSRFDIDFDRSRVGRKVAT 920
>YAR035w [I] KOG3719 Carnitine O-acyltransferase CPT2/YAT1
Length = 687
Score = 209 bits (531), Expect = 2e-53
Identities = 185/720 (25%), Positives = 304/720 (41%), Gaps = 115/720 (15%)
Query: 11 NLPKLPLPDLQKTLEEMEDSLKPLYYADGYYKHPLHPEESSELHENIEKFLHSNAAVKLQ 70
NL +LP+P LQ TL ++PL ++ + + +A L
Sbjct: 3 NLKRLPIPPLQDTLNRYLARVEPLQ----------DERQNRRTRRTVLSAENLDALNTLH 52
Query: 71 EKLKMFDRF------NGCYLDKLHLD---------INNHTSTKEIQDD-VLPRNPFLILA 114
E+L +D Y+++ D + N ++QDD + P
Sbjct: 53 ERLLEYDARLAESNPESSYIEQFWYDAYLLYDATVVLNVNPYFQLQDDPTIKDTPETAAQ 112
Query: 115 EDATSDISQAVRSGVLCSSALRFVSALRQNHLPPDCGSDGKPMSMLPYTNLFGTTRCPVF 174
+ Q R+ L +S L+F+ +R L D P+SM Y LFG++R P
Sbjct: 113 GPYGAHTVQVRRAARLTTSILKFIRQIRHGTLRTDTVRGKTPLSMDQYERLFGSSRIP-- 170
Query: 175 EHGEVESFDLNRPYDESDLEAELNNLSAQRRPSTASSEASNQPSANSDDDLEFFNVHGIT 234
+PS + D
Sbjct: 171 -------------------------------------PGPGEPSCHLQTDAT-------- 185
Query: 235 KKQYPDSKHIMIISKGQYYTLEVLDENDNALF-TDSQLSRVFQHIIDDSTTSYSLKRATA 293
S H++ + +GQ+Y +VLD + +F T QL II D+ ++ S +
Sbjct: 186 ------SHHVVAMYRGQFYWFDVLDTRNEPIFATPEQLEWNLYSIIMDAESAGS--GSAP 237
Query: 294 LGSLTSYSFKNWKYARKRLQKRYP----QELNVIDSALFIVVLDESTSTSDINEDCKR-L 348
G T+ S + W R L + L +IDSALF+V LD+ +D ++ R +
Sbjct: 238 FGVFTTESRRVWSNIRDYLFHADDCTNWRNLKLIDSALFVVCLDDVAFAADQQDELTRSM 297
Query: 349 YYGTSIVD-------DVTGFQVGSCTSRWYDKLQLVVTADSKAAVIWDSFTCDGSVVLRF 401
GTS ++ Q G+C +RWYDKLQL+VT + KA + ++ DG VLR
Sbjct: 298 LCGTSTINLDPHQHQPPLNVQTGTCLNRWYDKLQLIVTKNGKAGINFEHTGVDGHTVLRL 357
Query: 402 TSDIYAESILRLAREVHAGDPH-FSLWPQVPKASSKDAWTEKFSKIT------WSFSHIL 454
+DIY +SIL AR V FS P +SS + + IT W + L
Sbjct: 358 ATDIYTDSILSFARGVTKNVVDIFSDDDGKPSSSSLASAAHSANLITIPRKLEWRTDNFL 417
Query: 455 NTHVHLSETKLTDLISKHDIVHTTIPFGRRTAQKLGV----RADSLIQIALQIAHYALYG 510
+ +H +ET+++DLIS+++ V+ + F A + D+ +Q Q+A++ALYG
Sbjct: 418 QSSLHFAETRISDLISQYEFVN--LDFSNYGASHIKTVFKCSPDAFVQQVFQVAYFALYG 475
Query: 511 KMVFSFEPVSTRFFQNSRSTFIPIQTQELLELCQLFISNSLNETGKLEKFITACNDHSER 570
+ +EP T+ FQN R+ I T + + + ++ K++ AC HS+
Sbjct: 476 RFETVYEPAMTKAFQNGRTEAIRSVTGQSKLFVKSLLDQDASDATKIQLLHDACTAHSQI 535
Query: 571 IQKAQRGTGFEKHFNAIKYLFKFHDHFDIGLSPEEFEISSKVFNDAMLEPFSAPELIASN 630
++ +G G ++H A+ L+ + L P +F D L SN
Sbjct: 536 TRECSQGLGQDRHLYALYCLWNQWYKDKLELPP--------IFRDKSWTTMQNNVLSTSN 587
Query: 631 CGNSAMTAFGVTPAVPQGFGIGYIIKNEQCDITLTSQYRQGRRLAFMLKWVLTEINNYWE 690
CGN + +FG P GFGIGYII++ + ++S++RQ R A +++ L EI+ ++
Sbjct: 588 CGNPCLKSFGFGPVTANGFGIGYIIRDHSVSVVVSSRHRQTARFASLMEKSLLEIDRIFK 647
>Hs4503023 [I] KOG3719 Carnitine O-acyltransferase CPT2/YAT1
Length = 658
Score = 130 bits (328), Expect = 7e-30
Identities = 154/676 (22%), Positives = 284/676 (41%), Gaps = 112/676 (16%)
Query: 9 EKNLPKLPLPDLQKTLEEMEDSLKPLYYADGYYKHPLHPEESSELHEN-IEKFLHSNAAV 67
+ +LP+LP+P L+ T+ + KPL DG ++ E+ + EN I K LH V
Sbjct: 46 QDSLPRLPIPKLEDTIRRYLSAQKPLLN-DGQFRKT---EQFCKSFENGIGKELHEQL-V 100
Query: 68 KLQEKLKMFDRFNGCYLDKLHLDINNHTSTKEIQDDVLPRNPFLILAEDATSDIS-QAVR 126
L ++ K +G + D ++L + VL NPF+ D S+ + Q R
Sbjct: 101 ALDKQNKHTSYISGPWFD-MYLSARDSV--------VLNFNPFMAFNPDPKSEYNDQLTR 151
Query: 127 SGVLCSSALRFVSALRQNHLPPDCGSDGKPMSMLPYTNLFGTTRCPVFEHGEVESFDLNR 186
+ + SA+RF+ LR L P E F LN
Sbjct: 152 ATNMTVSAIRFLKTLRAGLLEP-------------------------------EVFHLNP 180
Query: 187 PYDESDLEAELNNLSAQRRPSTASSEASNQPSANSDDDLEFFNVHGITKKQYPD------ 240
++ L PS+ S + +A D ++F + T+ P
Sbjct: 181 AKSDTITFKRLIRFV----PSSLSWYGAYLVNAYPLDMSQYFRLFNSTRLPKPSRDELFT 236
Query: 241 ---SKHIMIISKGQYYTLEVLDENDNALFTDSQLSRVFQHIIDDSTTSYSLKRATALGSL 297
++H++++ KG +Y +VLD++ N + + S++ ++I+ DS+ + L L
Sbjct: 237 DDKARHLLVLRKGNFYIFDVLDQDGN-IVSPSEIQAHLKYILSDSSPAPEFP----LAYL 291
Query: 298 TSYSFKNWKYARKRLQKRYPQE-LNVIDSALFIVVLDESTSTSDINEDCKRLYYGTSIVD 356
TS + W R++L +E L +DSA+F + LD+ ++ L+
Sbjct: 292 TSENRDIWAELRQKLMSSGNEESLRKVDSAVFCLCLDDFPIKDLVHLSHNMLH------- 344
Query: 357 DVTGFQVGSCTSRWYDK-LQLVVTADSKAAVIWDSFTCDGSVVLRFTSDIYAESILRLAR 415
G T+RW+DK L++ D AV ++ DG VLRF ++++ +S A
Sbjct: 345 -------GDGTNRWFDKSFNLIIAKDGSTAVHFEHSWGDGVAVLRFFNEVFKDSTQTPA- 396
Query: 416 EVHAGDPHFSLWPQVPKASSKDAWTEKFSKITWSFSHILNTHVHLSETKLTDLISKHDIV 475
+ PQ A++ T + K+ + + L T + ++ K + I
Sbjct: 397 ----------VTPQSQPATTDSTVTVQ--KLNFELTDALKTGITAAKEKFDATMKTLTI- 443
Query: 476 HTTIPF---GRRTAQKLGVRADSLIQIALQIAHYALYGKMVFSFEPVSTRFFQNSRSTFI 532
+ F G+ +K + D++ Q+A Q+A YG+ V ++E ST F++ R+ I
Sbjct: 444 -DCVQFQRGGKEFLKKQKLSPDAVAQLAFQMAFLRQYGQTVATYESCSTAAFKHGRTETI 502
Query: 533 PIQTQELLELCQLFISN-SLNETGKLEKFITACND-HSERIQKAQRGTGFEKHFNAIKYL 590
+ + F+ S + G+L++ + C+ H + ++A G GF++H A+++
Sbjct: 503 RPASVYTKRCSEAFVREPSRHSAGELQQMMVECSKYHGQLTKEAAMGQGFDRHLFALRH- 561
Query: 591 FKFHDHFDIGLSPEEFEISSKVFNDAMLEPFSAPELIASNCGNSAMTAFGVTPAVPQGFG 650
L+ + I +++ D + L S + A+ G P V GFG
Sbjct: 562 ----------LAAAKGIILPELYLDPAYGQINHNVLSTSTLSSPAVNLGGFAPVVSDGFG 611
Query: 651 IGYIIKNEQCDITLTS 666
+GY + + ++S
Sbjct: 612 VGYAVHDNWIGCNVSS 627
>7292290 [I] KOG3719 Carnitine O-acyltransferase CPT2/YAT1
Length = 667
Score = 127 bits (320), Expect = 6e-29
Identities = 161/702 (22%), Positives = 281/702 (39%), Gaps = 119/702 (16%)
Query: 3 MSTFINEKNLPKLPLPDLQKTLEEMEDSLKPLYYADGYYKHPLHPEESSELHENIEKFLH 62
+ T +++LP+LP+P L+ + ++ KPL L P E ++ + +E+F
Sbjct: 36 LPTLYFQRSLPRLPIPLLENSCRRFLEATKPL----------LSPAEQAQTQQTVEQF-R 84
Query: 63 SNAAVKLQEKLKMFDRFNG--CYLDKLHLDINNHTSTKEIQDDVLPRNPFLILAEDATSD 120
++L KLK D N Y+ + D+ + L NP L++ DA +
Sbjct: 85 QGIGMELHAKLKSHDAENKHTSYISQPWFDMY----LADRAPLPLNYNPLLVMKSDARPE 140
Query: 121 ISQ-AVRSGVLCSSALRFVSALRQNHLPP----------DCGSDGKPMSMLPYTNLFGTT 169
Q VR+ L S+LRF +L+ + L P D S + M + P F T
Sbjct: 141 YQQQVVRATNLIISSLRFWRSLQADLLEPEVYHMNAKKSDTSSYRRWMKVAP--KAFATY 198
Query: 170 RCPVFEHGEVESFDLNRPYDESDLEAELNNLSAQRRPSTASSEASNQPSANSDDDLEFFN 229
F+ ++ NR + S + P D+ +
Sbjct: 199 ASYAFKAFPLDMSQYNRLFGTSRI-----------------------PRIGKDELV---- 231
Query: 230 VHGITKKQYPDSKHIMIISKGQYYTLEVLDENDNALFTDSQLSRVFQHIIDDSTTSYSLK 289
Q PD+KHI+++ +G Y + VLD + L R+ + D+ +
Sbjct: 232 -------QSPDAKHILVMRRGHMYAVNVLDSSGYIESPSVILGRLRAVLKLDADREAA-- 282
Query: 290 RATALGSLTSYSFKNWKYARKRL---QKRYPQELNVIDSALFIVVLD-ESTSTSDINEDC 345
+ LG LTS W R+ K +D+ALF V LD E + N+
Sbjct: 283 -SVPLGVLTSGQRDEWAKTRQHFVSNTKNADLLEREVDAALFCVCLDGEEDGVFNENQQE 341
Query: 346 KRLYYGTSIVDDVTGFQVGSCTSRWYDK-LQLVVTADSKAAVIWDSFTCDGSVVLRFTSD 404
L + G +RW+DK + L+++AD A+ ++ DG VLR+ ++
Sbjct: 342 PLLKH----------LLAGKAQNRWFDKSISLLISADGTTAINFEHSWGDGVAVLRYFNE 391
Query: 405 IYAESILRLAREVHAGDPHFSLWPQVPKASSKDAWTEKFSK---ITWSFSHILNTHVHLS 461
+Y +++ + P V + FS I + + V +
Sbjct: 392 LYKDTLKQ---------------PFVSTETVHTPAEGDFSNVRPINFEIDDATKSAVSEA 436
Query: 462 ETKLTDLISKHDIVHTTIP-FGRRTAQKLGVRADSLIQIALQIAHYALYGKMVFSFEPVS 520
K ++ D+ P + T ++ G+ DS+IQ++ Q+A+ Y V S+E S
Sbjct: 437 YNKNASIVDNLDMNVLKYPHINKPTCKQYGLSPDSIIQLSFQLAYRQAYSGYVGSYESCS 496
Query: 521 TRFFQNSRSTFIPIQTQELLELCQLFI--SNSLNETGKLEKFITACND-HSERIQKAQRG 577
T F++ R+ + T + C+ + S G+L I C+ H + ++A G
Sbjct: 497 TSAFRHGRTETMRPCTNATRDFCEAILQPERSKPSAGELRAMIDNCSKVHGQLTKEAAMG 556
Query: 578 TGFEKHFNAIKYLFKFHDHFDIGLS-PEEFEISS-KVFNDAMLEPFSAPELIASNCGNSA 635
GF++H A++ H G+ P+ +E + K N+ ++ S G+ A
Sbjct: 557 QGFDRHLFALR-----HTAQKEGIPIPDLYETEAYKRINNNIIS--------TSTLGSDA 603
Query: 636 MTAFGVTPAVPQGFGIGYIIKNEQCDITLTSQYRQGRRLAFM 677
+ A P V GFGIGY I+N+ +T+ Q F+
Sbjct: 604 LLAGSFGPVVKNGFGIGYSIQNDFAGAIVTTYKNQADGKVFI 645
>YML042w [I] KOG3717 Carnitine O-acyltransferase CRAT
Length = 670
Score = 108 bits (270), Expect = 4e-23
Identities = 129/673 (19%), Positives = 270/673 (39%), Gaps = 115/673 (17%)
Query: 5 TFINEKNLPKLPLPDLQKTLEEMEDSLKPLYYADGYYKHPLHPEESSELHENIEKFLHSN 64
TF +++LP LP+P+L+ TL++ +++P + E+ E + + K +
Sbjct: 67 TFAKQQDLPSLPVPELKSTLDKYLQTIRPF----------CNDVETFERQQLLCKDFSEH 116
Query: 65 AAVKLQEKLKMFDRFNGCYLDKLHLDINNHTSTKEIQDDVLPRNPFLILAEDATSDISQA 124
LQ++LK + ++ K + S + D ++P + + +S+
Sbjct: 117 MGPILQDRLKEYANDKRNWMAKFW----DEQSYLQYNDPIVPYVSYFYSHMPLPNHLSKI 172
Query: 125 -----VRSGVLCSSALRFVSALRQNHLPPDCGSDGKPMSMLPYTNLFGTTRCPVFEHGEV 179
+++ + S+ ++F+ A++ LP + G P M ++ +F T+R P
Sbjct: 173 DNDPLIKATAIISTVVKFIEAIKDESLPVEI-IKGMPFCMNSFSLMFNTSRLP------- 224
Query: 180 ESFDLNRPYDESDLEAELNNLSAQRRPSTASSEASNQPSANSDDDLEFFNVHGITKKQYP 239
+P N D ++ F++V+
Sbjct: 225 -----------------------------------GKPEDNQDTNI-FYSVY-------- 240
Query: 240 DSKHIMIISKGQYYTLEVLDENDNALFTDSQLSRVFQHIIDDSTTSYSLKRATALGSLTS 299
++ + I KG++Y L D ND L + +++ + S + L +GSLTS
Sbjct: 241 ENNFVTIAYKGKFYKLMTHDGNDKPLSENEIWRQLYSVVFQGSQSDPKLG---GIGSLTS 297
Query: 300 YSFKNWKYARKRLQKR--YPQELNVIDSALFIVVLDESTSTSDINEDCKRLYYGTSIVDD 357
W+ L K L I + F++ LD S + E + ++G I
Sbjct: 298 LPRDQWREVHLELMKDPISQDSLETIHKSSFMLCLDLDQSPVTLEEKSRNCWHGDGI--- 354
Query: 358 VTGFQVGSCTSRWYDK-LQLVVTADSKAAVIWDSFTCDGSVVLRFTSDIYAESILRLARE 416
+R+YDK LQ +VT + + + + DG+ L F ++ + + +L +
Sbjct: 355 ----------NRFYDKSLQFLVTGNGSSGFLAEHSKMDGTPTL-FLNNYVCQQLNKLDVD 403
Query: 417 VHAGDPHFSLWPQVPKASSKDAWTEKFSKITWSFSHILNTHVHLSETKLTDLISKHDI-V 475
+V SS A K ++ + + ++ + ++ + + I +HD+ V
Sbjct: 404 --------DFMRKVITPSSTVAM--KPMELPFIITPKIHKAIESAQLQFKETIGEHDLRV 453
Query: 476 HTTIPFGRRTAQKLGVRADSLIQIALQIAHYALYGKMVFSFEPVSTR-FFQNSRSTFIPI 534
+G+ ++ G+ D+ IQ +Q+A + + + ++E STR +F+ T +
Sbjct: 454 WHYNKYGKTFIKRHGMSPDAFIQQVIQLAVFKYLKRQLPTYEAASTRKYFKGRTETGRSV 513
Query: 535 QTQELLELCQLFISNSLNETGKLEKFITACNDHSERIQKAQRGTGFEKHFNAIKYLFKFH 594
T L E + + + K++ + +HS ++ A G G ++HF +K + K +
Sbjct: 514 STASL-EFVSKWQNGDVPIAEKIQALKHSAKEHSTYLKNAANGNGVDRHFFGLKNMLKSN 572
Query: 595 DHFDIGLSPEEFEISSKVFNDAMLEPFSAPELIASNCGNSAMTAFGVTPAVPQGFGIGYI 654
D + +F D + S + S + +G + GFG+ Y+
Sbjct: 573 D-----------DQIPPLFKDPLFNYSSTWLISTSQLSSEYFDGYGWSQVNDNGFGLAYM 621
Query: 655 IKNEQCDITLTSQ 667
+ NE I + ++
Sbjct: 622 LNNEWLHINIVNK 634
>CE12132 [I] KOG3716 Carnitine O-acyltransferase CPTI
Length = 748
Score = 99.4 bits (246), Expect = 2e-20
Identities = 95/385 (24%), Positives = 176/385 (45%), Gaps = 45/385 (11%)
Query: 228 FNVHGITKKQYPD------SKHIMIISKGQYYTLEVLDENDNALFTDSQLSRVFQHII-- 279
+N I KQY +KH++++ +Y +++ D N L+T QL+++ ++
Sbjct: 277 YNGCRIPGKQYDSFQWNKPAKHVILVHDCTWYKVDICDSNGQ-LYTVDQLAKIVAEVMGR 335
Query: 280 DDSTTSYSLKRATALGSLTSYSFKNWKYARKR--LQKRYPQEL-NVIDSALFIVVLDEST 336
DD + Y + SLT+ W R++ L+ ++ Q+L I++A F++ +D
Sbjct: 336 DDKSKGYLRN----IASLTTDRRTEWCSNRQKFFLENKHNQKLLQQIETAQFVMSVD--- 388
Query: 337 STSDINEDCKRLYYGTSIVDDVTGFQVGSCTSRWYDK-LQLVVTADSKAAVIWDSFTCDG 395
D+N + + + D+ GS ++RW DK + V A +A + CDG
Sbjct: 389 --GDLNWGVETTEQLSKYMKDMLA---GSGSNRWVDKTMNYAVDASGRAGATGEHSPCDG 443
Query: 396 SVVLRFTSDIYAESILRLAREVHAGDPHFSLWPQVPKASSKDAWTEKFS-----KITWSF 450
+ + D E++L + ++V P ++ K + +TEK S K+ +
Sbjct: 444 AEL-----DHLCENVLNVDKQVLVS-PSTEEQLEIIKMT----FTEKNSLRLAQKLDFQE 493
Query: 451 SHILNTHVHL---SETKLTDLISKHDIVHTTIPFGRRTAQKLGVRADSLIQIALQIAHYA 507
+ T V+ K +D + H I T FG+ +K G+ D +Q+A+Q+A+Y
Sbjct: 494 VDGMETEVNRCFEQHHKASDDLHMHSIAFTD--FGKGRVKKCGISPDGFLQMAIQLANYY 551
Query: 508 LYGKMVFSFEPVSTRFFQNSRSTFIPIQTQELLELCQLFISNSLNETGKLEKFITACNDH 567
GK V ++EP S RF+ NSR+ + T + Q +S+ + + + AC H
Sbjct: 552 DQGKFVLTYEPGSVRFYANSRTETLRPVTDYSCKFVQAMLSDESTQKERRDLLKKACEAH 611
Query: 568 SERIQKAQRGTGFEKHFNAIKYLFK 592
E ++ G G ++H + L K
Sbjct: 612 VENCKEVMTGKGVDRHLFVLCVLAK 636
>CE27752 [I] KOG3716 Carnitine O-acyltransferase CPTI
Length = 737
Score = 97.8 bits (242), Expect = 6e-20
Identities = 81/370 (21%), Positives = 165/370 (43%), Gaps = 41/370 (11%)
Query: 239 PDSKHIMIISKGQYYTLEVLDENDNALFTDSQLSRVFQHII--DDSTTSYSLKRATALGS 296
P SKH++++ KG +Y ++ D N L++ L+++ I+ D + K +GS
Sbjct: 294 PPSKHVLLVHKGTWYKVDTFDRNGK-LYSVDNLAKIVSEIMHRQDKADGFLSK----IGS 348
Query: 297 LTSYSFKNWKYARKRL---QKRYPQELNVIDSALFIVVLDESTSTSDINEDCKRLYYGTS 353
LT+ W R++ K + L +I++A F+V +D + ++G
Sbjct: 349 LTTDRRTEWSINREKFFLNNKNNKKLLEIIETAQFVVAIDGTN------------HWGVE 396
Query: 354 IVDDVTGFQ----VGSCTSRWYDK-LQLVVTADSKAAVIWDSFTCDGSVVLRFTSDIYAE 408
V+ + G T+RW+DK + V + + CDG+ + D E
Sbjct: 397 STKQVSRYMKDMLAGDGTNRWFDKTMNYAVDETGRGGATGEHSPCDGAEL-----DHLCE 451
Query: 409 SILRLAREVHAGDPHFSLWPQVPKASSKDAWTEKFS-KITWSFSHILNTHV---HLSETK 464
+ L + +++ P ++ + +D + K + K+ + + + + + + TK
Sbjct: 452 NFLNIDKQI-LKSPSKEEQLEIATVTEQDLKSLKLAEKLDFEIVDGMESEIERCYEAHTK 510
Query: 465 LTDLISKHDIVHTTIPFGRRTAQKLGVRADSLIQIALQIAHYAL--YGKMVFSFEPVSTR 522
+ + H +V + FG+ ++ G+ D +Q+A+Q+A+Y GK ++EP S R
Sbjct: 511 SFNDLHMHSMVF--LDFGKGKLKECGISPDGFVQMAIQLAYYKAGDQGKFTQTYEPGSIR 568
Query: 523 FFQNSRSTFIPIQTQELLELCQLFISNSLNETGKLEKFITACNDHSERIQKAQRGTGFEK 582
F+ NSR+ + T+ E + +S+ + + + AC H ++ G GF++
Sbjct: 569 FYANSRTETLRPVTKASCEFVEAMLSDKSDIASRRKLLKEACEVHVNNCKEIMLGNGFDR 628
Query: 583 HFNAIKYLFK 592
H + L K
Sbjct: 629 HLFVLCVLAK 638
>Hs4758050 [I] KOG3716 Carnitine O-acyltransferase CPTI
Length = 772
Score = 97.4 bits (241), Expect = 8e-20
Identities = 135/671 (20%), Positives = 243/671 (36%), Gaps = 132/671 (19%)
Query: 9 EKNLPKLPLPDLQKTLEEMEDSLKPLYYADGYYKHPLHPEESSELHENIEKFLHSNAAVK 68
+ +LPKLP+P + T++ +S++PL + YY+ L + K A +
Sbjct: 170 QTSLPKLPVPRVSATIQRYLESVRPLLDDEEYYRMEL-----------LAKEFQDKTAPR 218
Query: 69 LQEKLKMFDRFNGCYLD-----------KLHLDINNHTSTKEIQDDVLPRNPFLILAEDA 117
LQ+ L + + Y+ + L +N S + D VL +N
Sbjct: 219 LQKYLVLKSWWASNYVSDWWEEYIYLRGRSPLMVN---SNYYVMDLVLIKN--------- 266
Query: 118 TSDISQAVRSGVLCSSALRFVSALRQNHLPPDCGSDGKPMSMLPYTNLFGTTRCPVFEHG 177
+D+ QA R G + + + + L + + P PM +F TTR
Sbjct: 267 -TDV-QAARLGNIIHAMIMYRRKLDREEIKPVMALGIVPMCSYQMERMFNTTRI------ 318
Query: 178 EVESFDLNRPYDESDLEAELNNLSAQRRPSTASSEASNQPSANSDDDLEFFNVHGITKKQ 237
P ++D+ L +LS
Sbjct: 319 ---------PGKDTDV---LQHLS------------------------------------ 330
Query: 238 YPDSKHIMIISKGQYYTLEVLDENDNALFTDSQLSRVFQHIIDDSTTSYSLKRATALGSL 297
DS+H+ + KG+++ L + + L L FQ I+DD + + L +L
Sbjct: 331 --DSRHVAVYHKGRFFKLWLYE--GARLLKPQDLEMQFQRILDDPSPPQPGEEK--LAAL 384
Query: 298 TSYSFKNWKYARKRL--QKRYPQELNVIDSALFIVVLDESTSTSDINEDCKRLYYGTSIV 355
T+ W AR+ + L I+ A F V LDE + + D ++ YG +++
Sbjct: 385 TAGGRVEWAQARQAFFSSGKNKAALEAIERAAFFVALDEESYSYDPEDEASLSLYGKALL 444
Query: 356 DDVTGFQVGSCTSRWYDK-LQLVVTADSKAAVIWDSFTCDGSVVLRFTSDIYAESILRLA 414
G+C +RW+DK L+ + + + + D ++ + L
Sbjct: 445 H-------GNCYNRWFDKSFTLISFKNGQLGLNAEHAWADAPIIGHLWEFVLGTDSFHLG 497
Query: 415 REVHA---GDPHFSLWPQVPKASSKDAWTEKFSKITWSFSHILNTHVHLSETKLTDLISK 471
G P+ +L P +++ W + S L
Sbjct: 498 YTETGHCLGKPNPALAPP--------------TRLQWDIPKQCQAVIESSYQVAKALADD 543
Query: 472 HDIV-HTTIPFGRRTAQKLGVRADSLIQIALQIAHYALYGKMVFSFEPVSTRFFQNSRST 530
++ +PFG+ +K D+ +QIALQ+AH+ GK ++E TR F+ R+
Sbjct: 544 VELYCFQFLPFGKGLIKKCRTSPDAFVQIALQLAHFRDRGKFCLTYEASMTRMFREGRTE 603
Query: 531 FIPIQTQELLELCQLFISNSLNETGKLEKFITACNDHSERIQKAQRGTGFEKHFNAIKYL 590
+ T E Q + S + + F A H + A G G ++H + +
Sbjct: 604 TVRSCTSESTAFVQAMMEGSHTKADLRDLFQKAAKKHQNMYRLAMTGAGIDRHLFCLYLV 663
Query: 591 FKF---HDHFDIGLSPEEFEISSKVFNDAMLEPFSAPELIASNCGNSAMTAFGVTPAVPQ 647
K+ F + E + +S+ + + F PE ++ G G P
Sbjct: 664 SKYLGVSSPFLAEVLSEPWRLSTSQIPQSQIRMFD-PEQHPNHLGAGG----GFGPVADD 718
Query: 648 GFGIGYIIKNE 658
G+G+ Y+I E
Sbjct: 719 GYGVSYMIAGE 729
>Hs4503021 [I] KOG3716 Carnitine O-acyltransferase CPTI
Length = 773
Score = 97.4 bits (241), Expect = 8e-20
Identities = 101/430 (23%), Positives = 178/430 (40%), Gaps = 41/430 (9%)
Query: 240 DSKHIMIISKGQYYTLEVLDENDNALFTDSQLSRVFQHIIDDSTTSYSLKRATALGSLTS 299
DSKHI++ +G+Y+ + + +D L ++ + Q I+D+ TS L +LT+
Sbjct: 330 DSKHIVVYHRGRYFKVWLY--HDGRLLKPREMEQQMQRILDN--TSEPQPGEARLAALTA 385
Query: 300 YSFKNWKYARKRL--QKRYPQELNVIDSALFIVVLDESTSTSDINEDCKRLYYGTSIVDD 357
W R+ + + Q L+ ++ A F V LDE T +ED TS+
Sbjct: 386 GDRVPWARCRQAYFGRGKNKQSLDAVEKAAFFVTLDE-TEEGYRSEDPD-----TSMDSY 439
Query: 358 VTGFQVGSCTSRWYDK-LQLVVTADSKAAVIWDSFTCDGSVVLRFTSDIYAESILRLARE 416
G C RW+DK VV + K + + D +V + + L+L
Sbjct: 440 AKSLLHGRCYDRWFDKSFTFVVFKNGKMGLNAEHSWADAQIVAHLWEYVMSIDSLQLG-- 497
Query: 417 VHAGDPHFS--LWPQVPKASSKDAWTEKFSKITWSFSHILNTHVHLSETKLTDLISKHDI 474
+A D H + P +P + W I ++ T ++ + D + H
Sbjct: 498 -YAEDGHCKGDINPNIPYPTRLQ-WD-----IPGECQEVIETSLNTANLLAND-VDFHSF 549
Query: 475 VHTTIPFGRRTAQKLGVRADSLIQIALQIAHYALYGKMVFSFEPVSTRFFQNSRSTFIPI 534
+ FG+ +K D+ +Q+ALQ+AHY GK ++E TR F+ R+ +
Sbjct: 550 PF--VAFGKGIIKKCRTSPDTFVQLALQLAHYKDMGKFCLTYEASMTRLFREGRTETVRS 607
Query: 535 QTQELLELCQLFISNSLNETGKLEKFITACNDHSERIQKAQRGTGFEKHFNAIKYLFKF- 593
T E + + + + +L+ F A H + A G+G ++H + + K+
Sbjct: 608 CTTESCDFVRAMVDPAQTVEQRLKLFKLASEKHQHMYRLAMTGSGIDRHLFCLYVVSKYL 667
Query: 594 --HDHFDIGLSPEEFEISSKVFNDAMLEPF---SAPELIASNCGNSAMTAFGVTPAVPQG 648
F + E + +S+ +E F + PE ++S G FG P G
Sbjct: 668 AVESPFLKEVLSEPWRLSTSQTPQQQVELFDLENNPEYVSSGGG------FG--PVADDG 719
Query: 649 FGIGYIIKNE 658
+G+ YI+ E
Sbjct: 720 YGVSYILVGE 729
>CE14398 [I] KOG3716 Carnitine O-acyltransferase CPTI
Length = 746
Score = 97.4 bits (241), Expect = 8e-20
Identities = 91/368 (24%), Positives = 163/368 (43%), Gaps = 43/368 (11%)
Query: 230 VHGITKKQYPDSKHIMIISKGQYYTLEVLDENDNALFTDSQLSRVFQHIIDDSTTSYSLK 289
+HGI KHI+++ +G+YY + V+D+ +N ++T QL+++F +I +
Sbjct: 299 LHGI-------QKHIVVVLRGKYYKIHVVDDKNN-IYTVEQLTKIFHEMISRDEKEEGV- 349
Query: 290 RATALGSLTSYSFKNWKYARKRL---QKRYPQELNVIDSALFIVVLDESTSTSDINEDCK 346
+ +LT + +W R++ + Q L I+ A+F LDE+ D D K
Sbjct: 350 -IGKIAALTHDTRDSWHRNRQKYFLGNVKNAQILKEIECAVFFFTLDEN---DDYGYDEK 405
Query: 347 RLYYGTSIVDDVTGFQVGSCTSRWYDK-LQLVVTADSKAAVIWDSFTCDGSVVLRFTSDI 405
+ ++ + + G T+RW DK L + + +++ + DG+ D
Sbjct: 406 KPEVLSNFLANCLS---GDGTNRWVDKSLNYICSKNARCGGTTEHSIADGAEF-----DH 457
Query: 406 YAESILRLAREVHAGDPHFSLWPQVPKASSKDAWTEKFSKITWSFSHILNTHVHLSE--T 463
E+ + + EV L + + K A E+ K + + LN V E +
Sbjct: 458 IMENFVYVDLEV--------LKYKSIEEQEKMAVIEENDKKSLKLATPLNFEVPDQEMLS 509
Query: 464 KLTDLISKHDIVHTTIP--------FGRRTAQKLGVRADSLIQIALQIAHYALYGKMVFS 515
++T H I + FG+ +K GV D+ IQ+A+Q+A+Y GK V +
Sbjct: 510 EITRCYDAHQIAKNDLDLYALAFRDFGKGRIKKCGVSPDAFIQMAIQLANYRDQGKFVLT 569
Query: 516 FEPVSTRFFQNSRSTFIPIQTQELLELCQLFISNSLNETGKLEKFITACNDHSERIQKAQ 575
+EP S RFF NSR+ + E + ++ + + K+ AC H R +K
Sbjct: 570 YEPASARFFANSRTETLRTVNDHSCEFVEAMLNANETKEAKIALLKKACETHVLRNKKCM 629
Query: 576 RGTGFEKH 583
G G ++H
Sbjct: 630 VGQGVDRH 637
>CE18907 [I] KOG3719 Carnitine O-acyltransferase CPT2/YAT1
Length = 646
Score = 95.1 bits (235), Expect = 4e-19
Identities = 151/693 (21%), Positives = 258/693 (36%), Gaps = 129/693 (18%)
Query: 9 EKNLPKLPLPDLQKTLEEMEDSLKPLYYADGYYKHPLHPEESSELHENIEKFLHSNAAVK 68
+K+L +LP+P L T+ S K + L P+ ++ I F +N K
Sbjct: 39 QKSLRRLPIPKLPDTVNRYLASSKAV----------LSPDVFAKTEATIRSF-EANEGPK 87
Query: 69 LQEKLKMFDRFNG--CYLDKLHLDINNHTSTKEIQDDVLPRNPFLILAEDATSDIS-QAV 125
LQE L +D+ + Y+ + D+ + NPF++ A D + Q
Sbjct: 88 LQEALLEYDKAHRDTSYISEPWFDMYLRARVPV----AVNYNPFMMYAPDPNPKFNDQLT 143
Query: 126 RSGVLCSSALRFVSALRQNHLPPDC------GSDGKPMSML-----PYTNLFGTTRCPVF 174
R+ L S R +L +N L P+ SD K + P + FG F
Sbjct: 144 RATNLAISYARIKRSLDENLLGPEVFHMNPKKSDTKLFRTICKTLPPSLSWFGAVAFKAF 203
Query: 175 EHGEVESFDLNRPYDESDLEAELNNLSAQRRPSTASSEASNQPSANSDDDLEFFNVHGIT 234
P D S ++ R P + D+ + +
Sbjct: 204 ------------PLDMSQYKSLF---CGSRIPK-------------KEKDMLYLDA---- 231
Query: 235 KKQYPDSKHIMIISKGQYYTLEVLDENDNALFTDSQLSRVFQHIIDDSTTSYSLKRATAL 294
KH + KG Y + + D+ D L + I+ + + +++
Sbjct: 232 -----SQKHFVAFYKGHPYAVRIFDD-DGKLLDAEDVHASLAWILSNGKEAAP---ESSI 282
Query: 295 GSLTSYSFKNWKYARKRLQKRYPQE-LNVIDSALFIVVLDESTSTSDINEDCKRLYYGTS 353
GSLTS +W AR L+ E L ID LF + LD+ + E+ KRL
Sbjct: 283 GSLTSLDRDSWAEARVELENAGNGEYLKKIDGGLFAICLDDLKT-----EEHKRLVQSLL 337
Query: 354 IVDDVTGFQVGSCTSRWYDK-LQLVVTADSKAAVIWDSFTCDGSVVLRFTSDIYAESILR 412
I DD +RW+DK Q ++ A+ +A + ++ DG VLR + + ++
Sbjct: 338 IGDDAR--------NRWFDKCFQTIIDANGQATINFEHSWGDGVAVLRLMEESFKDT--- 386
Query: 413 LAREVHAGDPHFSLWPQVPKASSKDAWTEKFSKITWSFSHILNTHVHLSETKLTDLISKH 472
HF PK+ + K+T S ++K++D KH
Sbjct: 387 -------NKNHFVSPDDTPKSHNPAHVQALEFKLTDSL-----------KSKISDAQKKH 428
Query: 473 -----DIVHTTIPF---GRRTAQKLGVRADSLIQIALQIAHYALYGKMVFSFEPVSTRFF 524
D+ T+ F R +K + DS++Q+A+Q+A Y+LY + V ++E ST F
Sbjct: 429 VSANSDLDFATMEFEGLNRDLIKKTKLSPDSVMQLAIQMAFYSLYKEFVPTYESCSTAAF 488
Query: 525 QNSRSTFIPIQTQELLELCQLFISNSLNETGKLEKFITACN-DHSERIQKAQRGTGFEKH 583
R+ + T + + + +L +T C+ H + +++A G G+++H
Sbjct: 489 LKGRTECMRSATSATRAATLAILEENRKDVRQL---LTDCSTQHFQLVKEASMGQGYDRH 545
Query: 584 FNAIKYLFKFHDHFDIGLSPEEFEISSKVFNDAMLEPFSAPELIASNCGNSAMTAFGVTP 643
+K + + + F D L S + G P
Sbjct: 546 LLGLKI-----------TAQRLSQPTPDFFQDPGYTRMGHFVLSTSTLSTDTIVFGGFGP 594
Query: 644 AVPQGFGIGYIIKNEQCDITLTSQYRQGRRLAF 676
V GFGIGY + + ++S + AF
Sbjct: 595 VVQDGFGIGYNVVPNKLGAVISSNKSKRDAAAF 627
>Hs21618334 [I] KOG3717 Carnitine O-acyltransferase CRAT
Length = 605
Score = 89.0 bits (219), Expect = 3e-17
Identities = 137/651 (21%), Positives = 253/651 (38%), Gaps = 116/651 (17%)
Query: 12 LPKLPLPDLQKTLEEMEDSLKPLYYADGYYKHPLHPEESSELHENIEKFLHSNAA-VKLQ 70
LP+LP+P LQ++L+ +L+P+ + EE + + +++F S +LQ
Sbjct: 14 LPRLPVPPLQQSLDHYLKALQPI----------VSEEEWAHTKQLVDEFQASGGVGERLQ 63
Query: 71 EKLKMFDRFNGCYLDKLHLDINNHTSTKEIQDDVLPRNPFLILAEDATSDISQAVR-SGV 129
+ L+ R +L + L + Q V+ +P ++L + D+ +R +
Sbjct: 64 KGLERRARKTENWLSEWWLKT---AYLQYRQPVVIYSSPGVMLPKQDFVDLQGQLRFAAK 120
Query: 130 LCSSALRFVSALRQNHLPPDCGSDGKPMSMLPYTNLFGTTRCPVFEHGEVESFDLNRPYD 189
L L F + LP + GKP+ M Y + + R P
Sbjct: 121 LIEGVLDFKVMIDNETLPVEY-LGGKPLCMNQYYQILSSCRVP----------------- 162
Query: 190 ESDLEAELNNLSAQRRPSTASSEASNQPSANSDDDLEFFNVHGITKKQYPDSKHIMIISK 249
+ ++N S ++P T HI ++
Sbjct: 163 -GPKQDTVSNFSKTKKPPT----------------------------------HITVVHN 187
Query: 250 GQYYTLEVLDENDNALFTDS---QLSRVFQHIIDDSTTSYSLKRATALGSLTSYSFKNWK 306
Q++ L+V + L D QL +++ + + +G LTS +W
Sbjct: 188 YQFFELDVYHSDGTPLTADQIFVQLEKIWNSSLQTNKEP--------VGILTSNHRNSWA 239
Query: 307 YARKRLQKRYPQELNV--IDSALFIVVLDESTSTSDINEDCKRLYYGTSIVDDVTGFQVG 364
A L K +V I ++F V LD + ++ED R + ++ G ++
Sbjct: 240 KAYNTLIKDKVNRDSVRSIQKSIFTVCLDATMPR--VSEDVYRSHVAGQMLHG-GGSRLN 296
Query: 365 SCTSRWYDK-LQLVVTADSKAAVIWDSFTCDGSVVLRFTSDIYAESILRLAREVHAGDPH 423
S +RW+DK LQ +V D ++++ +G ++ + + P
Sbjct: 297 S-GNRWFDKTLQFIVAEDGSCGLVYEHAAAEGPPIVTLLDYVIE----------YTKKPE 345
Query: 424 FSLWPQVPKASSKDAWTEKFSKITWSFSHILNTHVHLSETKLTDLISKHDI-VHTTIPFG 482
P VP K K+ ++ + + + + ++ L+ +I DI V FG
Sbjct: 346 LVRSPMVPLPMPK--------KLRFNITPEIKSDIEKAKQNLSIMIQDLDITVMVFHHFG 397
Query: 483 RRTAQKLGVRADSLIQIALQIAHYALYGKMVFSFEPVSTRFFQNSRSTFIPIQTQELLEL 542
+ + + D+ IQ+ALQ+A+Y +YG+ ++E S R F R+ I + + L
Sbjct: 398 KDFPKSEKLSPDAFIQMALQLAYYRIYGQACATYESASLRMFHLGRTDTIRSASMDSLTF 457
Query: 543 CQLFISNSLNETGKLEKFITACNDHSERIQKAQRGTGFEKHFNAIKYLFKFHDHFDIGLS 602
+ +S+ E K+E A H +A RG F++H + K D+
Sbjct: 458 VKAMDDSSVTEHQKVELLRKAVQAHRGYTDRAIRGEAFDRHLLGL----KLQAIEDLVSM 513
Query: 603 PEEFEISSKVFNDAMLEPFSAPELIASNCGNSAMTAFGVTPAVPQGFGIGY 653
P+ F +S + AM S ++ A + FG P VP G+G+ Y
Sbjct: 514 PDIFMDTS--YAIAMHFHLSTSQVPAK---TDCVMFFG--PVVPDGYGVCY 557
>Hs21618331 [I] KOG3717 Carnitine O-acyltransferase CRAT
Length = 626
Score = 89.0 bits (219), Expect = 3e-17
Identities = 137/651 (21%), Positives = 253/651 (38%), Gaps = 116/651 (17%)
Query: 12 LPKLPLPDLQKTLEEMEDSLKPLYYADGYYKHPLHPEESSELHENIEKFLHSNAA-VKLQ 70
LP+LP+P LQ++L+ +L+P+ + EE + + +++F S +LQ
Sbjct: 35 LPRLPVPPLQQSLDHYLKALQPI----------VSEEEWAHTKQLVDEFQASGGVGERLQ 84
Query: 71 EKLKMFDRFNGCYLDKLHLDINNHTSTKEIQDDVLPRNPFLILAEDATSDISQAVR-SGV 129
+ L+ R +L + L + Q V+ +P ++L + D+ +R +
Sbjct: 85 KGLERRARKTENWLSEWWLKT---AYLQYRQPVVIYSSPGVMLPKQDFVDLQGQLRFAAK 141
Query: 130 LCSSALRFVSALRQNHLPPDCGSDGKPMSMLPYTNLFGTTRCPVFEHGEVESFDLNRPYD 189
L L F + LP + GKP+ M Y + + R P
Sbjct: 142 LIEGVLDFKVMIDNETLPVEY-LGGKPLCMNQYYQILSSCRVP----------------- 183
Query: 190 ESDLEAELNNLSAQRRPSTASSEASNQPSANSDDDLEFFNVHGITKKQYPDSKHIMIISK 249
+ ++N S ++P T HI ++
Sbjct: 184 -GPKQDTVSNFSKTKKPPT----------------------------------HITVVHN 208
Query: 250 GQYYTLEVLDENDNALFTDS---QLSRVFQHIIDDSTTSYSLKRATALGSLTSYSFKNWK 306
Q++ L+V + L D QL +++ + + +G LTS +W
Sbjct: 209 YQFFELDVYHSDGTPLTADQIFVQLEKIWNSSLQTNKEP--------VGILTSNHRNSWA 260
Query: 307 YARKRLQKRYPQELNV--IDSALFIVVLDESTSTSDINEDCKRLYYGTSIVDDVTGFQVG 364
A L K +V I ++F V LD + ++ED R + ++ G ++
Sbjct: 261 KAYNTLIKDKVNRDSVRSIQKSIFTVCLDATMPR--VSEDVYRSHVAGQMLHG-GGSRLN 317
Query: 365 SCTSRWYDK-LQLVVTADSKAAVIWDSFTCDGSVVLRFTSDIYAESILRLAREVHAGDPH 423
S +RW+DK LQ +V D ++++ +G ++ + + P
Sbjct: 318 S-GNRWFDKTLQFIVAEDGSCGLVYEHAAAEGPPIVTLLDYVIE----------YTKKPE 366
Query: 424 FSLWPQVPKASSKDAWTEKFSKITWSFSHILNTHVHLSETKLTDLISKHDI-VHTTIPFG 482
P VP K K+ ++ + + + + ++ L+ +I DI V FG
Sbjct: 367 LVRSPMVPLPMPK--------KLRFNITPEIKSDIEKAKQNLSIMIQDLDITVMVFHHFG 418
Query: 483 RRTAQKLGVRADSLIQIALQIAHYALYGKMVFSFEPVSTRFFQNSRSTFIPIQTQELLEL 542
+ + + D+ IQ+ALQ+A+Y +YG+ ++E S R F R+ I + + L
Sbjct: 419 KDFPKSEKLSPDAFIQMALQLAYYRIYGQACATYESASLRMFHLGRTDTIRSASMDSLTF 478
Query: 543 CQLFISNSLNETGKLEKFITACNDHSERIQKAQRGTGFEKHFNAIKYLFKFHDHFDIGLS 602
+ +S+ E K+E A H +A RG F++H + K D+
Sbjct: 479 VKAMDDSSVTEHQKVELLRKAVQAHRGYTDRAIRGEAFDRHLLGL----KLQAIEDLVSM 534
Query: 603 PEEFEISSKVFNDAMLEPFSAPELIASNCGNSAMTAFGVTPAVPQGFGIGY 653
P+ F +S + AM S ++ A + FG P VP G+G+ Y
Sbjct: 535 PDIFMDTS--YAIAMHFHLSTSQVPAK---TDCVMFFG--PVVPDGYGVCY 578
>Hs20546734 [I] KOG3716 Carnitine O-acyltransferase CPTI
Length = 803
Score = 88.6 bits (218), Expect = 4e-17
Identities = 100/475 (21%), Positives = 192/475 (40%), Gaps = 46/475 (9%)
Query: 198 NNLSAQRRPSTASSEASNQPSANSDDDLEFFNVHGITK---KQYPDSKHIMIISKGQYYT 254
+ L+ Q P T SA + + G+ K + DS+H+ + +G+++
Sbjct: 284 HRLNRQEIPPTLLMGMRPLCSAQYEKIFNTTRIPGVQKDYIRHLHDSQHVAVFHRGRFFR 343
Query: 255 LEVLDENDNALFTDSQLSRVFQHIIDDSTTSYSLKRATALGSLTSYSFKNWKYARKRLQK 314
+ + N+L + L + FQ I+DD S + L +LT+ W R L+
Sbjct: 344 MGT--HSRNSLLSPRALEQQFQRILDDP--SPACPHEEHLAALTAAPRGTWAQVRTSLKT 399
Query: 315 RYPQELNVIDSALFIVVLDESTSTSDINEDCKRL-YYGTSIVDDVTGFQVGSCTSRWYDK 373
+ + L ++ A F V LD + + L Y +++ G RW+DK
Sbjct: 400 QAAEALEAVEGAAFFVSLDAEPAGLTREDPAASLDAYAHALL-------AGRGHDRWFDK 452
Query: 374 -LQLVVTADSKAAVIWDSFTCDGSVVLRFTSDIYAESILRLAREVHAGDPHFSLWPQVPK 432
L+V ++ K + + D + A +L ++ D H P
Sbjct: 453 SFTLIVFSNGKLGLSVEHSWADCPISGHMWEFTLATECFQLG---YSTDGHCKGHP---- 505
Query: 433 ASSKDAWTEKFSKITWSFSHILNTHVHLSETKLTDLISKHDIVHTTIPF---GRRTAQKL 489
D + ++ W +++ + L+ + ++S++ H +PF G+ ++
Sbjct: 506 ----DPTLPQPQRLQWDLPDQIHSSISLA-LRGAKILSENVDCHV-VPFSLFGKSFIRRC 559
Query: 490 GVRADSLIQIALQIAHYALYGKMVFSFEPVSTRFFQNSRSTFIPIQTQELLELCQLFISN 549
+ +DS IQIALQ+AH+ G+ ++E TR F R+ + T+E +
Sbjct: 560 HLSSDSFIQIALQLAHFRDRGQFCLTYESAMTRLFLEGRTETVRSCTREACNFVRAMEDK 619
Query: 550 SLNETGKLEKFITACNDHSERIQKAQRGTGFEKHFNAIKYLFKF---HDHFDIGLSPEEF 606
+ L F A + H ++ A G G ++H A+ + +F F + E++
Sbjct: 620 EKTDPQCLALFRVAVDKHQALLKAAMSGQGVDRHLFALYIVSRFLHLQSPFLTQVHSEQW 679
Query: 607 EISSKVFNDAMLEPFSA---PELIASNCGNSAMTAFGVTPAVPQGFGIGYIIKNE 658
++S+ + F P+ ++S G FG PA G+G+ YI +
Sbjct: 680 QLSTSQIPVQQMHLFDVHNYPDYVSSGGG------FG--PADDHGYGVSYIFMGD 726
>CE28125 [I] KOG3716 Carnitine O-acyltransferase CPTI
Length = 728
Score = 87.0 bits (214), Expect = 1e-16
Identities = 94/436 (21%), Positives = 178/436 (40%), Gaps = 47/436 (10%)
Query: 238 YPDSKHIMIISKGQYYTLEVLDENDNALFTDSQLSRVFQHIIDDSTTSYSLKRATALGSL 297
+ D+KHI + +G ++ L V N L +L + I+ + T + L SL
Sbjct: 279 WDDAKHIAVYCRGVWFKLIV--HNGKRLLEACELQVQYDAIL--AHTHEPSEGEMHLASL 334
Query: 298 TSYSFKNWKYARKRLQKRYPQE--LNVIDSALFIVVLDESTSTSDINEDCKRLYYGTSIV 355
T+ +W R+ + + LN I+ A F+V+LD+ + D + K ++ +++
Sbjct: 335 TAGERADWAKTRRAHFRSGVNKTSLNDIERAAFVVILDDEETHYDPQDPSKLDHWAHNLL 394
Query: 356 DDVTGFQVGSCTSRWYDK-LQLVVTADSKAAVIWDSFTCDGSVVLRFTSDIYAESILRLA 414
G RW+DK L+++ + + + D +V+ FT + I+ +
Sbjct: 395 H-------GKAHDRWFDKSFNLIISKNGHVGINTEHSWGDAAVMAHFTEWSLLQDIVFIG 447
Query: 415 REVHA---GDPHFSLWPQVPKASSKDAWTEKFSKITWSFSHILNTHVHLSETKLTDLISK 471
+ + G+P L P+ K ++ K + ++ L V +S TD
Sbjct: 448 YDENGRCKGEPKEKLTPERLKWEIPAPALDQIRK-SMEVANALIADVEMSLLVWTD---- 502
Query: 472 HDIVHTTIPFGRRTAQKLGVRADSLIQIALQIAHYALYGKMVFSFEPVSTRFFQNSRSTF 531
+G+ A+KL V D+ +Q+ LQ ++ K ++E TR F+ R+
Sbjct: 503 ---------YGKGFAKKLKVSPDAFLQMTLQYTYFKNQNKFSLTYEASMTRLFREGRTET 553
Query: 532 IPIQTQELLELCQLFISNSLNETGKLEKFITACNDHSERIQKAQRGTGFEKHFNAI---- 587
+ T + + + + S +L+ AC+ H E + A G G ++H A+
Sbjct: 554 VRSCTVQSSDFVRSMLDASKTPQDRLQLLRKACDKHQELYRDAMCGQGVDRHLFALYVIK 613
Query: 588 KYLFKFHDHFDIGLSPEEFEISSKVFNDAMLEPFSAPELIASNCGNSAMTAF-----GVT 642
+YL + FD + P + +S+ P + E A N G
Sbjct: 614 RYLEEESPFFD-NIFPPTYLLSTS------QTPMNQCEADAKGLSNEVRLRLITAGGGFG 666
Query: 643 PAVPQGFGIGYIIKNE 658
P +G+G+ YI+ E
Sbjct: 667 PVADRGYGVSYIVAGE 682
>HsM4755132 [I] KOG3717 Carnitine O-acyltransferase CRAT
Length = 605
Score = 86.7 bits (213), Expect = 1e-16
Identities = 137/651 (21%), Positives = 252/651 (38%), Gaps = 116/651 (17%)
Query: 12 LPKLPLPDLQKTLEEMEDSLKPLYYADGYYKHPLHPEESSELHENIEKFLHSNAA-VKLQ 70
LP+LP+P LQ++L+ +L+P+ + EE + + +++F S +LQ
Sbjct: 14 LPRLPVPPLQQSLDHYLKALQPI----------VSEEEWAHTKQLVDEFQASGGVGERLQ 63
Query: 71 EKLKMFDRFNGCYLDKLHLDINNHTSTKEIQDDVLPRNPFLILAEDATSDISQAVR-SGV 129
+ L R +L + L + Q V+ +P ++L + D+ +R +
Sbjct: 64 KGLGRRARKTENWLSEWWLKT---AYLQYRQPVVIYSSPGVMLPKQDFVDLQGQLRFAAK 120
Query: 130 LCSSALRFVSALRQNHLPPDCGSDGKPMSMLPYTNLFGTTRCPVFEHGEVESFDLNRPYD 189
L L F + LP + GKP+ M Y + + R P
Sbjct: 121 LIEGVLDFKVMIDNETLPVEY-LXGKPLCMNQYYQILSSCRVP----------------- 162
Query: 190 ESDLEAELNNLSAQRRPSTASSEASNQPSANSDDDLEFFNVHGITKKQYPDSKHIMIISK 249
+ ++N S ++P T HI ++
Sbjct: 163 -GPKQDTVSNFSKTKKPPT----------------------------------HITVVHN 187
Query: 250 GQYYTLEVLDENDNALFTDS---QLSRVFQHIIDDSTTSYSLKRATALGSLTSYSFKNWK 306
Q++ L+V + L D QL +++ + + +G LTS +W
Sbjct: 188 YQFFELDVYHSDGTPLTADQIFVQLEKIWNSSLQTNKEP--------VGILTSNHRNSWA 239
Query: 307 YARKRLQKRYPQELNV--IDSALFIVVLDESTSTSDINEDCKRLYYGTSIVDDVTGFQVG 364
A L K +V I ++F V LD + ++ED R + ++ G ++
Sbjct: 240 KAYNTLIKDKVNRDSVRSIQKSIFTVCLDATMPR--VSEDVYRSHVAGQMLHG-GGSRLN 296
Query: 365 SCTSRWYDK-LQLVVTADSKAAVIWDSFTCDGSVVLRFTSDIYAESILRLAREVHAGDPH 423
S +RW+DK LQ +V D ++++ +G ++ + + P
Sbjct: 297 S-GNRWFDKTLQFIVAEDGSCGLVYEHAAAEGFPIVTLLDYVIE----------YTKKPE 345
Query: 424 FSLWPQVPKASSKDAWTEKFSKITWSFSHILNTHVHLSETKLTDLISKHDI-VHTTIPFG 482
P VP K K+ ++ + + + + ++ L+ +I DI V FG
Sbjct: 346 LVXSPMVPLPMPK--------KLRFNITPEIKSDIEKAKQNLSIMIXXLDITVMVFHHFG 397
Query: 483 RRTAQKLGVRADSLIQIALQIAHYALYGKMVFSFEPVSTRFFQNSRSTFIPIQTQELLEL 542
+ + + D+ IQ+ALQ+A+Y +YG+ ++E S R F R+ I + + L
Sbjct: 398 KDFPKSEKLSPDAFIQMALQLAYYRIYGQACATYESXSLRMFHLGRTDTIRSASMDSLTF 457
Query: 543 CQLFISNSLNETGKLEKFITACNDHSERIQKAQRGTGFEKHFNAIKYLFKFHDHFDIGLS 602
+ +S+ E K+E A H +A RG F +H + K D+ +
Sbjct: 458 VKAMDDSSVTEHQKVELLRKAVQAHRGYTDRAIRGEAFGRHLLGL----KLQAIEDLVST 513
Query: 603 PEEFEISSKVFNDAMLEPFSAPELIASNCGNSAMTAFGVTPAVPQGFGIGY 653
P+ F +S + AM S ++ A + FG P VP G+G+ Y
Sbjct: 514 PDIFMDTS--YAIAMHFHLSTSQVPAK---TDCVMFFG--PVVPDGYGVCY 557
>HsM4557487 [I] KOG3717 Carnitine O-acyltransferase CRAT
Length = 626
Score = 86.7 bits (213), Expect = 1e-16
Identities = 137/651 (21%), Positives = 252/651 (38%), Gaps = 116/651 (17%)
Query: 12 LPKLPLPDLQKTLEEMEDSLKPLYYADGYYKHPLHPEESSELHENIEKFLHSNAA-VKLQ 70
LP+LP+P LQ++L+ +L+P+ + EE + + +++F S +LQ
Sbjct: 35 LPRLPVPPLQQSLDHYLKALQPI----------VSEEEWAHTKQLVDEFQASGGVGERLQ 84
Query: 71 EKLKMFDRFNGCYLDKLHLDINNHTSTKEIQDDVLPRNPFLILAEDATSDISQAVR-SGV 129
+ L R +L + L + Q V+ +P ++L + D+ +R +
Sbjct: 85 KGLGRRARKTENWLSEWWLKT---AYLQYRQPVVIYSSPGVMLPKQDFVDLQGQLRFAAK 141
Query: 130 LCSSALRFVSALRQNHLPPDCGSDGKPMSMLPYTNLFGTTRCPVFEHGEVESFDLNRPYD 189
L L F + LP + GKP+ M Y + + R P
Sbjct: 142 LIEGVLDFKVMIDNETLPVEY-LXGKPLCMNQYYQILSSCRVP----------------- 183
Query: 190 ESDLEAELNNLSAQRRPSTASSEASNQPSANSDDDLEFFNVHGITKKQYPDSKHIMIISK 249
+ ++N S ++P T HI ++
Sbjct: 184 -GPKQDTVSNFSKTKKPPT----------------------------------HITVVHN 208
Query: 250 GQYYTLEVLDENDNALFTDS---QLSRVFQHIIDDSTTSYSLKRATALGSLTSYSFKNWK 306
Q++ L+V + L D QL +++ + + +G LTS +W
Sbjct: 209 YQFFELDVYHSDGTPLTADQIFVQLEKIWNSSLQTNKEP--------VGILTSNHRNSWA 260
Query: 307 YARKRLQKRYPQELNV--IDSALFIVVLDESTSTSDINEDCKRLYYGTSIVDDVTGFQVG 364
A L K +V I ++F V LD + ++ED R + ++ G ++
Sbjct: 261 KAYNTLIKDKVNRDSVRSIQKSIFTVCLDATMPR--VSEDVYRSHVAGQMLHG-GGSRLN 317
Query: 365 SCTSRWYDK-LQLVVTADSKAAVIWDSFTCDGSVVLRFTSDIYAESILRLAREVHAGDPH 423
S +RW+DK LQ +V D ++++ +G ++ + + P
Sbjct: 318 S-GNRWFDKTLQFIVAEDGSCGLVYEHAAAEGFPIVTLLDYVIE----------YTKKPE 366
Query: 424 FSLWPQVPKASSKDAWTEKFSKITWSFSHILNTHVHLSETKLTDLISKHDI-VHTTIPFG 482
P VP K K+ ++ + + + + ++ L+ +I DI V FG
Sbjct: 367 LVXSPMVPLPMPK--------KLRFNITPEIKSDIEKAKQNLSIMIXXLDITVMVFHHFG 418
Query: 483 RRTAQKLGVRADSLIQIALQIAHYALYGKMVFSFEPVSTRFFQNSRSTFIPIQTQELLEL 542
+ + + D+ IQ+ALQ+A+Y +YG+ ++E S R F R+ I + + L
Sbjct: 419 KDFPKSEKLSPDAFIQMALQLAYYRIYGQACATYESXSLRMFHLGRTDTIRSASMDSLTF 478
Query: 543 CQLFISNSLNETGKLEKFITACNDHSERIQKAQRGTGFEKHFNAIKYLFKFHDHFDIGLS 602
+ +S+ E K+E A H +A RG F +H + K D+ +
Sbjct: 479 VKAMDDSSVTEHQKVELLRKAVQAHRGYTDRAIRGEAFGRHLLGL----KLQAIEDLVST 534
Query: 603 PEEFEISSKVFNDAMLEPFSAPELIASNCGNSAMTAFGVTPAVPQGFGIGY 653
P+ F +S + AM S ++ A + FG P VP G+G+ Y
Sbjct: 535 PDIFMDTS--YAIAMHFHLSTSQVPAK---TDCVMFFG--PVVPDGYGVCY 578
>7303736 [I] KOG3716 Carnitine O-acyltransferase CPTI
Length = 782
Score = 86.7 bits (213), Expect = 1e-16
Identities = 97/476 (20%), Positives = 183/476 (38%), Gaps = 62/476 (13%)
Query: 238 YPDSKHIMIISKGQYYTLEVLDENDNALFTDSQLSRVFQHIIDDSTTSYSLKRATALGSL 297
Y DS HI+++ KG YY + + + + +L + I+ T ++ L +L
Sbjct: 327 YRDSNHIVVLHKGCYYKMLIYYKG--RILRPCELQVQIEEILKGKATP--VEGEEHLAAL 382
Query: 298 TSYSFKNWKYARKRLQKRYPQE--LNVIDSALFIVVLDESTSTSDINEDCKRLYYGTSIV 355
T+++ W AR + L I+SA F++ LD+ D+ +G ++
Sbjct: 383 TAWNRSKWAEARNTFFSWGVNQTSLRTIESAAFVLSLDDEPFEFDLARPELLDNFGKKLL 442
Query: 356 DDVTGFQVGSCTSRWYDKLQLV-VTADSKAAVIWDSFTCDGSVVLRFTSDIYAESILRLA 414
G+ +RW+DK V V + + + D ++ ++ + ++
Sbjct: 443 H-------GNGYNRWFDKCFTVCVGTNGRVGFNAEHTWSDAAIASHMWENLIVDDLVSDG 495
Query: 415 REVHA---GDPHFSLWPQVPKASSKDAWTEKFSKITWSFSHILNT--HVHLSETKLTDLI 469
+ G P F P P +++TW L + TKL + +
Sbjct: 496 YDETGNTKGTPAFQ--PPTP------------TRLTWDLKPCLAQIEEATIDVTKLINEV 541
Query: 470 SKHDIVHTTIPFGRRTAQKLGVRADSLIQIALQIAHYALYGKMVFSFEPVSTRFFQNSRS 529
+ +VH +G+ +K + D+ IQ+ALQ+A+Y G+ ++E TR F+ R+
Sbjct: 542 NLRILVHQD--YGKGFMKKCRISPDAYIQMALQLAYYRDAGRFSLTYEASMTRLFREGRT 599
Query: 530 TFIPIQTQELLELCQLFISNSLNETGKLEKFITACNDHSERIQKAQRGTGFEKHFNAIKY 589
+ T E + + + +++ AC+ H Q A G G ++H +
Sbjct: 600 ETVRPCTIESSAWVKAMQNPNTTNDERVKMMQAACDRHQLGYQDAMCGRGIDRHLFCLYV 659
Query: 590 LFKFHDHFDIGLSPEEFEISSKVFNDAMLEPF----------SAPELIASNCGNSAMTAF 639
+ K+ E+ S N+ + EP+ P++ N
Sbjct: 660 VSKY------------LEVDSPFLNEVLSEPWRLSTSQTPHGQTPKMDLKKHPNCISAGG 707
Query: 640 GVTPAVPQGFGIGYIIKNE-----QCDITLTSQYRQGRRLAFMLKWVLTEINNYWE 690
G P G+G+ YII E T Q R A + L++I + +E
Sbjct: 708 GFGPVADDGYGVSYIIAGENLIFFHISAKTTCQQTDVHRFAQNISQALSDIRSMFE 763
>CE20086 [I] KOG3718 Carnitine O-acyltransferase CROT
Length = 608
Score = 84.0 bits (206), Expect = 9e-16
Identities = 122/595 (20%), Positives = 226/595 (37%), Gaps = 108/595 (18%)
Query: 3 MSTFINEKNLPKLPLPDLQKTLEEMEDSLKPLYYADGYYKHPLHPEESSELHENIEKFLH 62
MSTF + LP LP+P L +TLE+ DS + L P E + + + +F H
Sbjct: 1 MSTFSRQDQLPSLPVPSLVETLEKYIDSASAI----------LTPAEKARVEKEAHEFQH 50
Query: 63 SNAAVKLQEKLKMFDRFNGCYLDKLHLDINNHTSTKEIQDDVLPRNPFLILAEDATS--- 119
S +LQ L+ + + +L+ N +T +E P P++ T+
Sbjct: 51 SELGAQLQSALENRAKNHKNWLEDWWY--NAYTEIRE------PLAPYVSFGAMNTAYNC 102
Query: 120 -DISQAVRSGVLCSSALRFVSALRQNHLPPDCGSDGKPMSMLPYTNLFGTTRCPVFEHGE 178
D Q R+ + L +R P S G M + +LF + R P
Sbjct: 103 VDGGQVSRAADVLHHWLSVWDKVRHGKWPVT-SSRGVTWDMQQFHHLFSSNRTP------ 155
Query: 179 VESFDLNRPYDESDLEAELNNLSAQRRPSTASSEASNQPSANSDDDLEFFNVHGITKKQY 238
R D D +F TK++
Sbjct: 156 ------QRTRDTMD---------------------------------RYFK----TKEEG 172
Query: 239 PDSKHIMIISKGQYYTLEVLDENDNALFTDSQLSRVFQHIIDDSTTSYSLKRATALGSLT 298
H++I G ++ L +L+E+D+ + + ++ + + + D+S+ S + LT
Sbjct: 173 DTPTHVIICCDGCFWKLNILNEDDDTIKSPDEIYNMLKFVRDNSSDESSC----CVSKLT 228
Query: 299 SYSFKNWKYARKRLQKRYPQELNVIDSALFIVVLDESTSTSDINEDCKRLYYGTSIVDDV 358
+ + W R L + + + A+ +L S +D ++L ++ + D
Sbjct: 229 TTNRDVWSLNRDELLRVSSANIEYV-RAVETSILFLSMVPKKGGDDQQKLM--SNALQDE 285
Query: 359 TGFQVGSCTSRWYDK-LQLVVTADSKAAVIWDSFTCDGSVVLRFTSDIYAESILRLAREV 417
+ F W DK + + + D++ V D D V+L+ D A + +
Sbjct: 286 SWFV-------WQDKSVNITIYEDAQVMVQGDHSNIDAIVLLQ-VGDYVASRVRK----- 332
Query: 418 HAGDPHFSLWPQVPKASSKDAWTEKFSKITWSFSHILNTHVHLSET---KLTDLISKHDI 474
LW P + D E ++ + F+ L + ++ K L +
Sbjct: 333 -------QLWH--PAKTGSDLHFEFPERLIFEFNEPLRHAISFADVEFYKSKQLYRARGV 383
Query: 475 VHTTIPFGRRTAQKLGVRADSLIQIALQIAHYALYGKMVFSFEPVSTRFFQNSRSTFIPI 534
H +G + V D+++Q+ALQ+A +G +E STR F + R+ +
Sbjct: 384 HHHG--YGNELCRTAKVYTDTVVQLALQLAFLKTHGSFAPIYETASTRKFFHGRTETVRG 441
Query: 535 QTQELLELCQLFISNSLNETGKLEK-FITACNDHSERIQKAQRGTGFEKHFNAIK 588
T + + + + + NE L+K F +A N H++ + G GF++H +K
Sbjct: 442 CTSQFVRFAKALLGDQTNEKEDLKKLFDSAINAHNQLMADCMDGRGFDRHLMGLK 496
>Hs11038620 [I] KOG3717 Carnitine O-acyltransferase CRAT
Length = 630
Score = 82.4 bits (202), Expect = 3e-15
Identities = 130/553 (23%), Positives = 218/553 (38%), Gaps = 123/553 (22%)
Query: 9 EKNLPKLPLPDLQKTLEEMEDSLKPLYYADGYYKHPLHPEESSE---LHENIEKFLHSNA 65
E LPKLP+P LQ+TL ++ L + + K ++ L E +++ L
Sbjct: 10 ESGLPKLPVPPLQQTLATYLQCMRHLVSEEQFRKSQAIVQQFGAPGGLGETLQQKL---- 65
Query: 66 AVKLQEKLKMFDRFNGCYLDKLHLDINNHTSTKEIQDDVLPRN--PFLILAEDATSDISQ 123
L+ + K + + +L+ ++L NN + LP N P +I A
Sbjct: 66 ---LERQEKTANWVSEYWLNDMYL--NNRLA--------LPVNSSPAVIFARQHFPGTDD 112
Query: 124 AVR-SGVLCSSALRFVSALRQNHLPPDCGS---DGKPMSMLPYTNLFGTTRCPVFEHGEV 179
+R + L S L + + L + +P DC G+P+ M Y LF
Sbjct: 113 QLRFAASLISGVLSYKALLDSHSIPTDCAKPELSGQPLCMKQYYGLF------------- 159
Query: 180 ESFDLNRPYDESDLEAELNNLSAQRRPSTASSEASNQPSANSDDDLEFFNVHGITKKQYP 239
S+ R P Q S+ P
Sbjct: 160 ---------------------SSYRLPGHTQDTLVAQNSSIM-----------------P 181
Query: 240 DSKHIMIISKGQYYTLEV------LDENDNALFTDSQLSRVFQHIIDDSTTSYSLKRATA 293
+ +H+++ Q++ L+V L E D LFT QL ++ + ++ +R
Sbjct: 182 EPEHVIVACCNQFFVLDVVINFRRLSEGD--LFT--QLRKIVKMASNED------ERLPP 231
Query: 294 LGSLTSYSFKNWKYARKRLQKRYPQE--LNVIDSALFIVVLDE--STSTSDINEDCKRLY 349
+G LTS W AR L K L++I+ + +V LD SD + + L+
Sbjct: 232 IGLLTSDGRSEWAEARTVLVKDSTNRDSLDMIERCICLVCLDGPGGVELSDTHRALQLLH 291
Query: 350 YGTSIVDDVTGFQVGSCTSRWYDK-LQLVVTADSKAAVIWDSFTCDGSVVLRFTSDIYAE 408
G G+ +RWYDK LQ VV D+ V+ + DG V+++ T + +
Sbjct: 292 GG--------GYSKNGA-NRWYDKSLQFVVGRDATCGVVCEHSPFDGIVLVQCTEHLL-K 341
Query: 409 SILRLAREVHAGDPHFSLWPQVPKASSKDAWTEKFSKITWSFSHILNTHVHLSETKLTDL 468
+ + +R++ D L P+ ++ W S + H+ S KL +
Sbjct: 342 HMTQSSRKLIRADSVSEL--PAPR------------RLRWKCSPEIQGHLASSAEKLQRI 387
Query: 469 ISKHD-IVHTTIPFGRRTAQKLGVRADSLIQIALQIAHYALYGKMVFSFEPVSTRFFQNS 527
+ D IV+ +G+ +K D+ IQ+ALQ+A Y L+ ++V ++E S R FQ
Sbjct: 388 VKNLDFIVYKFDNYGKTFIKKQKCSPDAFIQVALQLAFYRLHRRLVPTYESASIRRFQEG 447
Query: 528 RSTFIPIQTQELL 540
R I T E L
Sbjct: 448 RVDNIRSATPEAL 460
>Hs10181098 [I] KOG3717 Carnitine O-acyltransferase CRAT
Length = 748
Score = 82.4 bits (202), Expect = 3e-15
Identities = 130/553 (23%), Positives = 218/553 (38%), Gaps = 123/553 (22%)
Query: 9 EKNLPKLPLPDLQKTLEEMEDSLKPLYYADGYYKHPLHPEESSE---LHENIEKFLHSNA 65
E LPKLP+P LQ+TL ++ L + + K ++ L E +++ L
Sbjct: 128 ESGLPKLPVPPLQQTLATYLQCMRHLVSEEQFRKSQAIVQQFGAPGGLGETLQQKL---- 183
Query: 66 AVKLQEKLKMFDRFNGCYLDKLHLDINNHTSTKEIQDDVLPRN--PFLILAEDATSDISQ 123
L+ + K + + +L+ ++L NN + LP N P +I A
Sbjct: 184 ---LERQEKTANWVSEYWLNDMYL--NNRLA--------LPVNSSPAVIFARQHFPGTDD 230
Query: 124 AVR-SGVLCSSALRFVSALRQNHLPPDCGS---DGKPMSMLPYTNLFGTTRCPVFEHGEV 179
+R + L S L + + L + +P DC G+P+ M Y LF
Sbjct: 231 QLRFAASLISGVLSYKALLDSHSIPTDCAKPELSGQPLCMKQYYGLF------------- 277
Query: 180 ESFDLNRPYDESDLEAELNNLSAQRRPSTASSEASNQPSANSDDDLEFFNVHGITKKQYP 239
S+ R P Q S+ P
Sbjct: 278 ---------------------SSYRLPGHTQDTLVAQNSSIM-----------------P 299
Query: 240 DSKHIMIISKGQYYTLEV------LDENDNALFTDSQLSRVFQHIIDDSTTSYSLKRATA 293
+ +H+++ Q++ L+V L E D LFT QL ++ + ++ +R
Sbjct: 300 EPEHVIVACCNQFFVLDVVINFRRLSEGD--LFT--QLRKIVKMASNED------ERLPP 349
Query: 294 LGSLTSYSFKNWKYARKRLQKRYPQE--LNVIDSALFIVVLDE--STSTSDINEDCKRLY 349
+G LTS W AR L K L++I+ + +V LD SD + + L+
Sbjct: 350 IGLLTSDGRSEWAEARTVLVKDSTNRDSLDMIERCICLVCLDGPGGVELSDTHRALQLLH 409
Query: 350 YGTSIVDDVTGFQVGSCTSRWYDK-LQLVVTADSKAAVIWDSFTCDGSVVLRFTSDIYAE 408
G G+ +RWYDK LQ VV D+ V+ + DG V+++ T + +
Sbjct: 410 GG--------GYSKNGA-NRWYDKSLQFVVGRDATCGVVCEHSPFDGIVLVQCTEHLL-K 459
Query: 409 SILRLAREVHAGDPHFSLWPQVPKASSKDAWTEKFSKITWSFSHILNTHVHLSETKLTDL 468
+ + +R++ D L P+ ++ W S + H+ S KL +
Sbjct: 460 HMTQSSRKLIRADSVSEL--PAPR------------RLRWKCSPEIQGHLASSAEKLQRI 505
Query: 469 ISKHD-IVHTTIPFGRRTAQKLGVRADSLIQIALQIAHYALYGKMVFSFEPVSTRFFQNS 527
+ D IV+ +G+ +K D+ IQ+ALQ+A Y L+ ++V ++E S R FQ
Sbjct: 506 VKNLDFIVYKFDNYGKTFIKKQKCSPDAFIQVALQLAFYRLHRRLVPTYESASIRRFQEG 565
Query: 528 RSTFIPIQTQELL 540
R I T E L
Sbjct: 566 RVDNIRSATPEAL 578
>CE03306 [I] KOG3718 Carnitine O-acyltransferase CROT
Length = 557
Score = 82.0 bits (201), Expect = 4e-15
Identities = 130/601 (21%), Positives = 233/601 (38%), Gaps = 131/601 (21%)
Query: 1 MTMSTFINEKNLPKLPLPDLQKTLEEMEDSLKPLYYADGYYKHPLHPEE--SSELHENIE 58
MT STF + +LP LPLP+L++T+ + SL P+ D + SS+ + ++
Sbjct: 1 MTSSTFSEQNSLPSLPLPELEETIGKYLKSLVPIVPKDELETITTLANDFASSQNGQILQ 60
Query: 59 KFLHSNAAVKLQEKLKMFDRFNGCYLDKLHLDINNHTSTKEIQDDVLPRNPFLILAEDAT 118
+FL + K + D + YL +D +L +N ++ + +
Sbjct: 61 RFLKEKT---ISSKNWLEDWWYDAYLTN--------------RDSLLTQNMGAVVPKFSV 103
Query: 119 SDISQAVRSGVLCSSALRFVSALRQNHLPPDCGSDGKPMSMLPYTNLFGTTRCPVFEHGE 178
+D SQ + + + + S +RQ + S G M NLF R P
Sbjct: 104 NDSSQIESASHIIHHLMSYWSLIRQEKIEVT-KSRGNSWDMNQDYNLFNACRVPALPKDR 162
Query: 179 VESFDLNRPYDESDLEAELNNLSAQRRPSTASSEASNQPSANSDDDLEFFNVHGITKKQY 238
++ Y ++ E + PS
Sbjct: 163 IKR------YFRTEAEGKC-------------------PS-------------------- 177
Query: 239 PDSKHIMIISKGQYYTLEVLDENDNALFTDSQLSRVFQHIIDDSTTSYSLKRATALGSLT 298
H++I+ G + LE EN L ++ + I + S TS ++ LT
Sbjct: 178 ----HVIILCNGHVWKLETTCENSKFL-NIFEIQNALKRIKESSRTSVEC----SIVQLT 228
Query: 299 SYSFKNWKYARKRL---QKRYPQELNVIDSALFIVVLDESTSTSDINEDCKRLYYGTSIV 355
S NW R+ + R + + +DSA+F + L + D E+ + S +
Sbjct: 229 SLGRDNWAQIRESMIQNSNRNVELFHDVDSAVFCLTLSD-----DFVENESEVVRVRSTI 283
Query: 356 DDVTGFQV------GSCTSRWYDK-LQLVVTADSKAAVIWDSFTCDGSVVLRFTSDIYAE 408
Q+ GS + + DK L ++V D K TC + AE
Sbjct: 284 LHCLKLQLMKYSIFGSPLNAYCDKNLNIIVLRDGK--------TC-----------LQAE 324
Query: 409 SILRLAREVHAGDPHFSLWPQVPKASSKDAWTEKFSKITWSFSHILNTHVHLSETKLTDL 468
S + + S+ P +P KI + + ++ + +E L
Sbjct: 325 S---------SQNKSSSMQPVMPV------------KIEFLLTGSVSQKISEAERDFYFL 363
Query: 469 ISKHDI-VHTTIPFGRRTAQKLGVRADSLIQIALQIAHYALYGKMVFSFEPVSTRFFQNS 527
SK ++ V+ FG ++ + AD++IQIALQ+A+ + K+ ++E STR F +
Sbjct: 364 SSKTNVNVYHYTNFGATYCKQRTLYADTIIQIALQMAYLKTHNKLAPTYETASTRMFYHG 423
Query: 528 RSTFIPIQTQELLELCQLFISNSLNETGKLEKFITACNDHSERIQKAQRGTGFEKHFNAI 587
R+ + T ++ + +++ NET KL F A N H+ + A+ G G ++HF +
Sbjct: 424 RTETVRSLTTDMEKYLTACENSATNETLKL-LFFDAYNSHNTLMDAAREGKGIDRHFYGL 482
Query: 588 K 588
+
Sbjct: 483 R 483
>7300431 [I] KOG3717 Carnitine O-acyltransferase CRAT
Length = 622
Score = 78.6 bits (192), Expect = 4e-14
Identities = 105/466 (22%), Positives = 182/466 (38%), Gaps = 66/466 (14%)
Query: 240 DSKHIMIISKGQYYTLEVLDENDNALFTDSQLSRVFQHIIDDSTTSYSLKRATALGSLTS 299
+ +H+++I + Q Y + VL +D ++S+++ +++ D+ + + +G LT+
Sbjct: 159 EDRHVVVICRNQMYCV-VLQASDRGKLSESEIASQILYVLSDAPCLPA--KPVPVGLLTA 215
Query: 300 YSFKNWKYARKRLQK--RYPQELNVIDSALFIVVLDESTSTSDINEDCKRLYYGTSIVD- 356
W R+ LQ+ R + L +I++A ++ LDE + N + + T V
Sbjct: 216 EPRSTWARDREMLQEDERNQRNLELIETAQVVLCLDEPLAG---NFNARGFTGATPTVHR 272
Query: 357 ----DVT---------GFQVGSCTSRWYDK-LQLVVTADSKAAVIWDSFTCDGSVVLRFT 402
D T G + +RW+DK +QL++ D + ++ +G V++
Sbjct: 273 AGDRDETNMAHEMIHGGGSEYNSGNRWFDKTMQLIICTDGTWGLCYEHSCSEGIAVVQLL 332
Query: 403 SDIYAESILRLAREVHAGDPHFSLWPQVPKASSKDAWTEKFSKITWSFSHILNTHVHLSE 462
IY + + + G P L P ++ W L +
Sbjct: 333 EKIYKK--IEEHPDEDNGLPQHHLPPP--------------ERLEWHVGPQLQLRFAQAS 376
Query: 463 TKLTDLISKHDI-VHTTIPFGRRTAQKLGVRADSLIQIALQIAHYALYGKMVFSFEPVST 521
+ I D V+ +G+ + V D IQ+ALQ+AHY LYG++V ++E ST
Sbjct: 377 KSVDKCIDDLDFYVYRYQSYGKTFIKSCQVSPDVYIQLALQLAHYKLYGRLVATYESAST 436
Query: 522 RFFQNSRSTFIPIQTQELLE----LCQ-------LFISNSLNETGKLEKFITACNDHSER 570
R F + R I + E LE +CQ L E + KF DH
Sbjct: 437 RRFLHGRVDCIRAASTEALEWAKAMCQGEGANVPLESDREDEEESRKVKFSIYSKDHLRE 496
Query: 571 IQKAQRGTGFEKHFNAIKYLFKFHDHFDIGLSPEEFEISSKVFNDAMLEPFSAPELIASN 630
+ + E I L D +GL E++ + M E F I S
Sbjct: 497 LFRCAVARQTEVMVKNI--LGNGIDIPLLGLREASIEVTGE-----MHELFKDESYIISQ 549
Query: 631 C--------GNSAMTAFGVTPAVPQGFGIGYIIKNEQCDITLTSQY 668
C S + G P P+G+G Y EQ +++ Y
Sbjct: 550 CFLLSTSQVACSTDSFMGYGPVTPRGYGCSYNPHPEQIVFCVSAFY 595
>Hs10863953 [I] KOG3718 Carnitine O-acyltransferase CROT
Length = 612
Score = 75.1 bits (183), Expect = 4e-13
Identities = 119/598 (19%), Positives = 221/598 (36%), Gaps = 105/598 (17%)
Query: 5 TFINEKNLPKLPLPDLQKTLEEMEDSLKPLYYADGYYKHPLHPEESSELHENIEKFLHSN 64
TF + +LP LP+P L+++L++ +S+KP + EE + E ++KF S
Sbjct: 13 TFQYQDSLPSLPVPSLEESLKKYLESVKPF----------ANQEEYKKTEEIVQKF-QSG 61
Query: 65 AAVKLQEKLKMFDRFNGCYLDKLHLDINNHTSTKEIQDDVLPRNPFLILAEDATSDISQA 124
KL +KL + +L++ L++ A D+
Sbjct: 62 IGEKLHQKLLERAKGKRNWLEEWWLNV-------------------------AYLDVRIP 96
Query: 125 VRSGV-LCSSALRFVSALRQNHLPPDCGSDGKPMSM-----LPYTNLFGTTRCPVFEHGE 178
+ V A F +++ PP G+ + S+ L Y L + PV + G
Sbjct: 97 SQLNVNFAGPAAHF-----EHYWPPKEGTQLERGSITLWHNLNYWQLLRKEKVPVHKVG- 150
Query: 179 VESFDLNRPYDESDLEAELNNLSAQRRPSTASSEASNQPSANSDDDLEFFNVHGITKKQY 238
N P D + + P D + +F T+ +
Sbjct: 151 ------NTPLDMNQFRMLFSTCKG--------------PGITRDSIMNYFR----TESEG 186
Query: 239 PDSKHIMIISKGQYYTLEVLDENDNALFTDSQLSRVFQHIIDDSTTSYSLKRATALGSLT 298
HI+++ +G+ + +V+ E L T +L R +I +S + +LT
Sbjct: 187 RSPNHIVVLCRGRAFVFDVIHEG--CLVTPPELLRQLTYI---HKKCHSEPDGPGIAALT 241
Query: 299 SYSFKNWKYARKRLQKRYPQELNVID---SALFIVVLDESTSTSDINEDCKRLYYGTSIV 355
S W AR+ L P+ L +++ S+L + +++S S ED +
Sbjct: 242 SEERTRWAKAREYLIGLDPENLALLEKIQSSLLVYSMEDS-SPHVTPEDYSEI------- 293
Query: 356 DDVTGFQVGSCTSRWYDK-LQLVVTADSKAAVIWDSFTCDGSVVLRFTSDIYAESILRLA 414
+ +G T RW DK L+ ++ D D +++ + + +
Sbjct: 294 --IAAILIGDPTVRWGDKSYNLISFSNGVFGCNCDHAPFDAMIMVNISYYVDEKIFQNEG 351
Query: 415 REVHAGDPHFSLWPQVPKASSKDAWTEKFSKITWSFSHILNTHVHLSETKLTDLISKHDI 474
R W K E + +LN L +
Sbjct: 352 R-----------WKGSEKVRDIPLPEELIFIVD---EKVLNDINQAKAQYLREASDLQIA 397
Query: 475 VHTTIPFGRRTAQKLGVRADSLIQIALQIAHYALYGKMVFSFEPVSTRFFQNSRSTFIPI 534
+ FG++ + + D+ IQ+ALQ+A+Y L+G +E TR F + R+ +
Sbjct: 398 AYAFTSFGKKLTKNKMLHPDTFIQLALQLAYYRLHGHPGCCYETAMTRHFYHGRTETMRS 457
Query: 535 QTQELLELCQLFISNSLNETGKLEKFITACNDHSERIQKAQRGTGFEKHFNAIKYLFK 592
T E + CQ S+N + +K + A H++ ++ G GF++H + + K
Sbjct: 458 CTVEAVRWCQSMQDPSVNLRERQQKMLQAFAKHNKMMKDCSAGKGFDRHLLGLLLIAK 515
>CE21255 [I] KOG3716 Carnitine O-acyltransferase CPTI
Length = 746
Score = 74.7 bits (182), Expect = 6e-13
Identities = 88/365 (24%), Positives = 153/365 (41%), Gaps = 37/365 (10%)
Query: 239 PDSKHIMIISKGQYYTLEVLDENDNALFTDSQLSRVFQHIIDDSTTSYSLKRATALGSLT 298
PD+KHI + KG +Y +++ + + S+L + FQ I+D S S + L +LT
Sbjct: 301 PDAKHIAVYHKGCWYKIDIF--HGKRMVKPSELEKSFQEILD-SNDHISQQGEKYLSALT 357
Query: 299 SYSFKNWKYARKRLQKRYP-----QELNVIDSALFIVVLDESTSTSDINEDCKRLYYGTS 353
W AR R +K + L+ I+++L IV LDE D ++ K YG
Sbjct: 358 IGPRDLW--ARIRTEKFSKGGVNQESLSFIENSLEIVFLDEEERFFDEDDSTK---YGRE 412
Query: 354 IVDDVTGFQVGSCTSRWYDKLQLVV-TADSKAAVIWDSFTCDGSVVLRFTSDI-YAESIL 411
+ G W DK + + + + + + + CD + ++ I Y E
Sbjct: 413 YARALHG----DGYMLWCDKPSVYIFSKNGRFSSNAEHSPCDAMIYVQVREYIKYHEQF- 467
Query: 412 RLAREVHAGDPH-FSLWPQVPKASSK--DAWTEKFSKITWSFSHILNTHVHLSETKLTDL 468
+ D H VPKA D E I +F + + D
Sbjct: 468 ---ESPYGPDGHCVGSIEHVPKAERLCWDMDKETLDAIDEAF---------IISKGVADD 515
Query: 469 ISKHDIVHTTIPFGRRTAQKLGVRADSLIQIALQIAHYALYGKMVFSFEPVSTRFFQNSR 528
S ++V T +G+ +K V D+ IQ+ALQ+A++ GK ++EP R F+ R
Sbjct: 516 FSNANVVFTE--YGKDFMKKAKVSPDAYIQMALQMAYFKDQGKFEQTYEPAVMRLFKEGR 573
Query: 529 STFIPIQTQELLELCQLFISNSLNETGKLEKFITACNDHSERIQKAQRGTGFEKHFNAIK 588
+ + + + + + + KLEK AC+ H + + A G G ++H A+
Sbjct: 574 TETVRSCSIWSCDFVRTMLKKDVGAGKKLEKLKEACDHHQDYYRTAMAGKGVDRHLFALY 633
Query: 589 YLFKF 593
+ ++
Sbjct: 634 VVARY 638
>7298923 [I] KOG3717 Carnitine O-acyltransferase CRAT
Length = 638
Score = 70.5 bits (171), Expect = 1e-11
Identities = 84/362 (23%), Positives = 152/362 (41%), Gaps = 35/362 (9%)
Query: 239 PDSKHIMIISKGQYYTLEVLDENDNALFTDSQLSRVFQHIIDDSTTSYSLKRATALGSLT 298
PDS ++++I K +Y L++ + + L L+ ++I+ T + G LT
Sbjct: 207 PDSDYVVVIYKNHFYQLKIYSK-EGKLIAAPCLAAQLENIVLKET-----QVGVPYGILT 260
Query: 299 SYSFKNWKYARKRLQKRYPQE--LNVIDSALFIVVLDESTSTSDINEDCKRLYYGTSIVD 356
+ S NW A + L + L I ALF V LDE T + E + + S++
Sbjct: 261 TDSRDNWAEAYEYLVETPGNRDALKTIQGALFTVSLDEGTILKEGEETDELIL---SLIH 317
Query: 357 DVTGFQVGSCTSRWYDK-LQLVVTADSKAAVIWDSFTCDGSVVLRFTSDIYAESILRLAR 415
+G ++ S +RW DK +QLVV + ++ +G + + + +++ +
Sbjct: 318 G-SGSKINS-GNRWMDKTIQLVVNPNGNVGFTYEHSPAEGQPIA-----MMMDYVVQKMK 370
Query: 416 EVHAGDPHFSLWPQVPKASSKD---AWTEKFSKITWSFSHILNTHVHLSETKLTDLISKH 472
E DP F ++ S+D A +FS S LN + KL D +
Sbjct: 371 E----DPSFG------QSGSQDFAPAQKIQFSSSNKSLEKSLNV-AQENVDKLADALQMK 419
Query: 473 DIVHTTIPFGRRTAQKLGVRADSLIQIALQIAHYALYGKMVFSFEPVSTRFFQNSRSTFI 532
+ FG+ +K + DS +Q+ALQ+A Y ++ + +E R F R+ I
Sbjct: 420 VLKFNG--FGKDFIKKQRLGPDSFVQMALQLAFYKMHSEPPAQYESAHLRIFDGGRTETI 477
Query: 533 PIQTQELLELCQLFISNSLNETGKLEKFITACNDHSERIQKAQRGTGFEKHFNAIKYLFK 592
+ E L + ++ + + K A H + A +G G ++H +K +
Sbjct: 478 RSCSNESLAFSRAMQDPNVTDQERAAKLREAVVSHQTYAKLALQGKGVDRHLLGLKLMAL 537
Query: 593 FH 594
H
Sbjct: 538 EH 539
>CE17308 [I] KOG3717 Carnitine O-acyltransferase CRAT
Length = 627
Score = 68.2 bits (165), Expect = 5e-11
Identities = 82/349 (23%), Positives = 141/349 (39%), Gaps = 36/349 (10%)
Query: 323 IDSALFIVVLD----------ESTSTSDINEDCKRLYYGTSIVDDVTGFQVGSCTSRWYD 372
+ SALF+V LD ++ S S+ ++ Y T + F + +RWYD
Sbjct: 267 VKSALFVVCLDMEDPIDYGKNDTMSISEKEKEFVARGYSTLTGHGSSKFGL----NRWYD 322
Query: 373 K-LQLVVTADSKAAVIWDSFTCDGSVVLRFTSDIYAESILRLAREVHAGDPHFSLWPQVP 431
+QLVV++ + + T +G V++ AE+ +R A++ +W V
Sbjct: 323 ATIQLVVSSSGVNGLCIEHSTAEGIVIINM-----AETAIRYAQKYFKSK---MVWNDVR 374
Query: 432 KASSKDAWTEKFSKITWSFSHILNTHVHLSETKLTDLISKHDI-VHTTIPFGRRTAQKLG 490
K +TW FS + +L ++ ++ V FG+ + +
Sbjct: 375 NVHPKS--------LTWHFSENSRNILKKQAEVFDELANELELEVLIFNEFGKDSIKNWR 426
Query: 491 VRADSLIQIALQIAHYALYGKMVFSFEPVSTRFFQNSRSTFIPIQTQELLELCQLFISNS 550
V D IQ+ +Q+AHY +G +V ++E S R F R I TQE LE S
Sbjct: 427 VSPDGFIQLIMQLAHYKTHGHLVSTYESASVRRFGAGRVDNIRANTQEALEWVTAMASKK 486
Query: 551 LNETGKLEKFITACNDHSERIQKAQRGTGFEKHFNAIKYLFKFHDHFDIGLSPEEFEISS 610
++ KLE F A + + G G + H A+ L + + P F
Sbjct: 487 ESKERKLELFKKAVLKQVKVTLENISGYGVDNHLCALFCLAREREETTGEDIPSLF--LD 544
Query: 611 KVFNDAMLEPFSAPELIASNCGNSAMTAFGVTPAVPQGFGIGYIIKNEQ 659
++++ M P S ++ S +G V G+G Y I+ ++
Sbjct: 545 PLWSEVMRFPLSTSQVTTSLDIPDCYLTYGA--VVRDGYGCPYNIQPDR 591
>7301624 [I] KOG3718 Carnitine O-acyltransferase CROT
Length = 618
Score = 65.5 bits (158), Expect = 3e-10
Identities = 126/679 (18%), Positives = 244/679 (35%), Gaps = 127/679 (18%)
Query: 4 STFINEKNLPKLPLPDLQKTLEEMEDSLKPLYYADGYYKHPLHPEESSELHENIEKFLHS 63
+TF ++ LP LPLP+L+ T+E ++P EE ++ + I++F +
Sbjct: 15 NTFDFDETLPSLPLPELRDTMERYYSCIQPFGTK----------EELAQARKTIDEF-QN 63
Query: 64 NAAVKLQEKLKMFDRFNGCYLDKLHLDINNHTSTKEI---QDDVLPRNPFLILAEDATSD 120
+L E+LK +L D H + Q V+P ++ +
Sbjct: 64 GVGAQLHEQLKKRAAGMRNWLGTWWEDYGYHLIRMPLLPYQLMVMPSQLEMVGVPETPEY 123
Query: 121 ISQAVRSGVLCSSALRFVSALRQNHLPPDCGSDGK-PMSMLPYTNLFGTTRCPVFEHGEV 179
+ +++ + +L F R++ + P + GK S Y + F T R P E +
Sbjct: 124 MLKSLARHI--HHSLEFWDLTRKSSIKPLSSNGGKIKYSSALYKHFFSTCRVPGEEQDHI 181
Query: 180 ESFDLNRPYDESDLEAELNNLSAQRRPSTASSEASNQPSANSDDDLEFFNVHGITKKQYP 239
E H +TK +
Sbjct: 182 EK-------------------------------------------------HFLTKDEGK 192
Query: 240 DSKHIMIISKGQYYTLEVLDENDNALFTDS---QLSRVFQHIIDDSTTSYSLKRATALGS 296
H++I KG+ + + + E+D L L RV + I+D + +
Sbjct: 193 TPSHMLISGKGRQFIFDCVHEDDTILSAPEILVALQRV-RSILDYEPLG------DCVPT 245
Query: 297 LTSYSFKNWKYARKRLQK---RYPQELNVIDSALFIVVLDESTSTSDINEDCKRLYYGTS 353
L+ W R RL++ + L +++SA + E S D E C+ YG
Sbjct: 246 LSHDERSTWARNRNRLREISVANKETLLLVESACMEICWYEQ-SPKDYEESCQLGLYG-- 302
Query: 354 IVDDVTGFQVGSCTSRWYDKLQLVVTADSKAAVIWDSFTC-DGSVVLRFTSDIYAESILR 412
SRW D+ ++ + +C DG+V + + + + +
Sbjct: 303 -----------DLHSRWADRSSSIIAFRNGRCNWTGEHSCYDGTVSISYATFMQLSFL-- 349
Query: 413 LAREVHAGDPHFSLWPQVPKASSKDAWTEKFSKITWSFSHILNTHVHLSETKLTDLISKH 472
EV D W + K + + ++ + L + + + D
Sbjct: 350 ---EVPEPD-----WAEAEKGNVLEV-----KELHFQLDDTLKNEIKRVQKDIDDRGIDV 396
Query: 473 DIVHTTIP-FGRRTAQKLGVRADSLIQIALQIAHYALYGKMVFSFEPVSTRFFQNSRSTF 531
+ T +G+ + + DS +Q+ +Q A+Y ++ ++ ++E R + N R+
Sbjct: 397 TVTFTAFDDYGKDFMKTHRLHPDSFVQVVMQWAYYQMHKEIAPTYETALMRQYYNGRTET 456
Query: 532 IPIQTQELLELCQLFISNSLNETGKLEKFITACNDHSERIQKAQRGTGFEKHFNAIKYLF 591
+ T + E + + + + F A ++H + +A++G G ++H
Sbjct: 457 LRSCTSAVAEFLRASSNKQVGDMSLARAFRRAVDEHKHFMNEARKGHGIDRHL------- 509
Query: 592 KFHDHFDIGLSPEEFEISSKVFNDAMLEPFSAP----ELIASNCGNSAMTAFGVTPAVPQ 647
F + + E ++ F D + S L +S G +A F V P V
Sbjct: 510 -----FGLWCAAYESKMDIPAFYDDPMYTKSGGGGNFVLSSSTLGFTANVGF-VAPMVFD 563
Query: 648 GFGIGYIIKNEQCDITLTS 666
G+G+ Y I +E I T+
Sbjct: 564 GYGVFYSITSEAVFINTTA 582
>CE25326 [I] KOG3716 Carnitine O-acyltransferase CPTI
Length = 742
Score = 64.7 bits (156), Expect = 6e-10
Identities = 59/285 (20%), Positives = 127/285 (43%), Gaps = 32/285 (11%)
Query: 239 PDSKHIMIISKGQYYTLEVLDENDNALFTDSQLSRVFQHII--DDSTTSYSLKRATALGS 296
P S+H +++ KG +Y ++ DE D L++ ++L+++ + D +T + K + S
Sbjct: 281 PPSRHALVVHKGTWYKVDTCDE-DGRLYSVNELAKIVSELTTRQDKSTGFLCK----ISS 335
Query: 297 LTSYSFKNWKYARKRL---QKRYPQELNVIDSALFIVVLDESTSTSDINEDCKRLYYGTS 353
LT+ W R++ + L VI+++ +++ +D T+ + K Y
Sbjct: 336 LTADRRTEWSKNRRKFFLNNAHNKKLLEVIETSQYVISMD--TAKWGVETSDKMSVYMKD 393
Query: 354 IVDDVTGFQVGSCTSRWYDK-LQLVVTADSKAAVIWDSFTCDGSVVLRFTSDIYAESILR 412
++ G T+RW+DK + + A+ + + DG+ + D E+ L
Sbjct: 394 ML-------AGDGTNRWFDKTMNYAICANGRGGATGEHSPADGAEM-----DHVCENFLN 441
Query: 413 LAREVHAGDPHFSLWPQVPKASSKDAWTEKFSKITWSFSHILNTHV---HLSETKLTDLI 469
L +++ P ++ K + + K+ + L V + + TK +
Sbjct: 442 LDKQI-LKSPSKEEQLEIAKLDEPSNYLKLAEKLEFEVEEGLEEEVERCYEAHTKAVADL 500
Query: 470 SKHDIVHTTIPFGRRTAQKLGVRADSLIQIALQIAHYALYGKMVF 514
H I+ + FG+ +K G+ D +Q+A+Q+A++ + G+ F
Sbjct: 501 HVHSIIF--LDFGKGRLKKCGISPDGFVQMAIQLAYFEV-GRSAF 542
>Hs21618336 [I] KOG3717 Carnitine O-acyltransferase CRAT
Length = 544
Score = 59.7 bits (143), Expect = 2e-08
Identities = 53/210 (25%), Positives = 95/210 (45%), Gaps = 12/210 (5%)
Query: 445 KITWSFSHILNTHVHLSETKLTDLISKHDI-VHTTIPFGRRTAQKLGVRADSLIQIALQI 503
K+ ++ + + + + ++ L+ +I DI V FG+ + + D+ IQ+ALQ+
Sbjct: 298 KLRFNITPEIKSDIEKAKQNLSIMIQDLDITVMVFHHFGKDFPKSEKLSPDAFIQMALQL 357
Query: 504 AHYALYGKMVFSFEPVSTRFFQNSRSTFIPIQTQELLELCQLFISNSLNETGKLEKFITA 563
A+Y +YG+ ++E S R F R+ I + + L + +S+ E K+E A
Sbjct: 358 AYYRIYGQACATYESASLRMFHLGRTDTIRSASMDSLTFVKAMDDSSVTEHQKVELLRKA 417
Query: 564 CNDHSERIQKAQRGTGFEKHFNAIKYLFKFHDHFDIGLSPEEFEISSKVFNDAMLEPFSA 623
H +A RG F++H + K D+ P+ F +S + AM S
Sbjct: 418 VQAHRGYTDRAIRGEAFDRHLLGL----KLQAIEDLVSMPDIFMDTS--YAIAMHFHLST 471
Query: 624 PELIASNCGNSAMTAFGVTPAVPQGFGIGY 653
++ A + FG P VP G+G+ Y
Sbjct: 472 SQVPAK---TDCVMFFG--PVVPDGYGVCY 496
>7298001 [I] KOG3717 Carnitine O-acyltransferase CRAT
Length = 561
Score = 57.0 bits (136), Expect = 1e-07
Identities = 43/186 (23%), Positives = 83/186 (44%), Gaps = 11/186 (5%)
Query: 481 FGRRTAQKLGVRADSLIQIALQIAHYALYGKMVFSFEPVSTRFFQNSRSTFIPIQTQELL 540
+G+ + G+ DS IQ+AL +A+Y++YGK+ +E R F R+ I + E
Sbjct: 330 YGKCFIKAQGLNPDSYIQMALSLAYYSMYGKIPAQYESAHLRIFHEGRTETIRSTSNESK 389
Query: 541 ELCQLFISNSLNETGKLEKFITACNDHSERIQKAQRGTGFEKHFNAIKYLFKFHDHFDIG 600
S + + KL A + H + I++A G G ++H ++ + + G
Sbjct: 390 TFLLAMQSEKASMSEKLAALQKAVDAHEKLIKEAINGQGIDRHLFGLQEM-----ALEKG 444
Query: 601 LSPEEFEISSKVFNDAMLEPFSAPELIASNCGNSAMTAFGVTPAVPQGFGIGYIIKNEQC 660
+ EF S + F++ +A++ N A+G P + G+G+ Y K +
Sbjct: 445 MPIPEFFRSKGYVRSVTFQLFTSQ--VATS--NEGFMAYG--PLLSDGYGVCYNPKESKI 498
Query: 661 DITLTS 666
+++
Sbjct: 499 TFAISA 504
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.317 0.133 0.383
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 49,754,059
Number of Sequences: 60738
Number of extensions: 2123494
Number of successful extensions: 6373
Number of sequences better than 1.0e-05: 31
Number of HSP's better than 0.0 without gapping: 15
Number of HSP's successfully gapped in prelim test: 16
Number of HSP's that attempted gapping in prelim test: 6257
Number of HSP's gapped (non-prelim): 70
length of query: 865
length of database: 30,389,216
effective HSP length: 115
effective length of query: 750
effective length of database: 23,404,346
effective search space: 17553259500
effective search space used: 17553259500
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)