ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIV2716 good TR KOG4561 General function prediction only Uncharacterized conserved protein, contains TBC domain
r_klactIV2716 good TR KOG4561 Signal transduction mechanisms Uncharacterized conserved protein, contains TBC domain
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIV2716 927829 926981 -283
(283 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YJR116w [TR] KOG4561 Uncharacterized conserved protein contains ... 267 1e-71
SPAC17A2.02c [TR] KOG4561 Uncharacterized conserved protein cont... 133 3e-31
YPR114w [TR] KOG4561 Uncharacterized conserved protein contains ... 98 2e-20
Hs18545963 [TR] KOG4561 Uncharacterized conserved protein contai... 56 5e-08
At1g31300 [TR] KOG4561 Uncharacterized conserved protein contain... 49 6e-06
>YJR116w [TR] KOG4561 Uncharacterized conserved protein contains TBC domain
Length = 279
Score = 267 bits (682), Expect = 1e-71
Identities = 133/279 (47%), Positives = 187/279 (66%), Gaps = 4/279 (1%)
Query: 6 SSYFTGPELSDPLLSWSFDPSSENLYYRHLHEALISFVVYQFILYPFVVPKLNEWFFKEH 65
+S T L+ P SF P S NL HLHE + SFV YQ + + V P LN+ F++H
Sbjct: 4 NSTTTAIGLTSPFEKLSFFPHSSNLILAHLHEIIFSFVFYQ-LAFSVVAPFLNKVVFRKH 62
Query: 66 YTE-RDEPDKINFDIHTVSMIQSVVSLYLIWPLLWIPFGFNVATYYNSYASMVSAVSIGY 124
YT RD KI+F++HTVSMIQ+VVS ++ P L P +NV TY +SY+SMVS++S GY
Sbjct: 63 YTTIRDPLLKIDFNVHTVSMIQAVVSNTVLLPTLTTPMHYNVVTYTDSYSSMVSSLSAGY 122
Query: 125 FMWDLYICLRYFKLFGIGXXXXXXXXXXXXTITLHPVCQAWIGRFLSFEASTPFVNINWY 184
F+WDL +C+RYFKL+G+ ++L P CQ WIGRFL +EASTPFVNINW+
Sbjct: 123 FIWDLTMCVRYFKLYGLEFTGHAIGSVYVMLLSLRPFCQPWIGRFLIYEASTPFVNINWF 182
Query: 185 IIQLSRGSSKQVVPTWFNVLNGFLLISVFFFVRLVWGFVAVAILIYEMWQVWDQIPLYMT 244
I+Q + SK +P WFNV+NG LL++VFF VR+ WG +A A+L +MW+V D++P +
Sbjct: 183 IMQCN-AKSKNSIPLWFNVVNGLLLMTVFFVVRICWGSIASALLFRQMWKVRDELPKFSA 241
Query: 245 AVILGINVSLDFLNIHWFSKMLKIAKKMANGSKRVSKID 283
++ +N+ ++ LN+ WF KM++IAKK+A + SK+D
Sbjct: 242 VTMMSLNIFMNLLNVLWFKKMIRIAKKLAKPAP-TSKLD 279
>SPAC17A2.02c [TR] KOG4561 Uncharacterized conserved protein contains TBC domain
Length = 290
Score = 133 bits (335), Expect = 3e-31
Identities = 80/249 (32%), Positives = 131/249 (52%), Gaps = 14/249 (5%)
Query: 33 RHLHEALISFVVYQFI--LYPFVVPKLNEWFFKEHYTERDEPDKINFDIHTVSMIQSVVS 90
RH+H L+S + YQ I L P + L+ HY + + ++N+D H VS +QS+V
Sbjct: 38 RHMHVILLSALFYQIINILSPVISRHLST-----HYAKLSKKTRLNWDAHVVSSVQSIVL 92
Query: 91 LYLIWPLLWIPFGFNVATY-YNSYASMVSAVSIGYFMWDLYICLRYFKLFGIGXXXXXXX 149
+ L + L F + Y+ A + A++ GYF+WDLYI +RY + GIG
Sbjct: 93 ICLGYTCLKEVNAFPDKLFGYSVVAGDIYALTAGYFVWDLYITVRYVHITGIGFVIHAIA 152
Query: 150 XXXXXTITLHPVCQAWIGRFLSFEASTPFVNINWYIIQLSRGSSKQVVPTWFNVLNGFLL 209
T + P + +LS+E STPF+NI++++ + +R SK F ++NGF+L
Sbjct: 153 ALFVITFSYRPYLMYYGPTYLSWELSTPFLNIHYFLDKTNRTGSK------FQMINGFIL 206
Query: 210 ISVFFFVRLVWGFVAVAILIYEMWQVWDQIPLYMTAVILGINVSLDFLNIHWFSKMLKIA 269
I F VR+ WG+ + E+ + P ++ L N+SL+ LN+ W SKM+
Sbjct: 207 IVTFICVRIAWGWFSAYSTAIEILNHINVAPWALSLFYLAANMSLNCLNLFWVSKMIDAI 266
Query: 270 KKMANGSKR 278
++ A+G K+
Sbjct: 267 RRRAHGEKK 275
>YPR114w [TR] KOG4561 Uncharacterized conserved protein contains TBC domain
Length = 315
Score = 97.8 bits (242), Expect = 2e-20
Identities = 70/234 (29%), Positives = 109/234 (45%), Gaps = 25/234 (10%)
Query: 64 EHYTERDEPDKINFDIHTVSMIQSVVSLYLIWPLLWIPFGFNVATYYNSYA--------- 114
+HY ++ +H +S++QS+V LY L P + Y S++
Sbjct: 87 QHYKKKYTSLINQSSVHLISLLQSIVVLYYSLKFLLDPKA-SAEPYQTSHSRVFTENRDT 145
Query: 115 SMVSAVSIGYFMWDLYICLRY----FKLFGIGXXXXXXXXXXXXTITLHPVCQAWIGRFL 170
++ +IGYF+WD+YI Y F + GI I L P Q + FL
Sbjct: 146 QVICIFAIGYFVWDIYISTMYSTFPFVVHGI-------ISTVVFCIGLKPYIQYYAPVFL 198
Query: 171 SFEASTPFVNINWYIIQLSRGSSKQVVPTWFNVLNGFLLISVFFFVRLVWGFVAVAILIY 230
FE S P +N W+ I+ SK + +LN L+ VFF R+ WG+ + L Y
Sbjct: 199 MFELSNPSLNFRWFGIKFLPQKSKFC--SLLLLLNNLTLMVVFFAARIAWGWFQIGKLCY 256
Query: 231 EMWQVWDQ--IPLYMTAVILGINVSLDFLNIHWFSKMLKIAKKMANGSKRVSKI 282
+ +QV ++ ++ T VIL N LD LN+ WFS M+ +A K+ + V K+
Sbjct: 257 DFYQVRNEPGFLVFDTIVILAGNFVLDILNVIWFSTMVSVAAKVLKKGESVDKV 310
>Hs18545963 [TR] KOG4561 Uncharacterized conserved protein contains TBC domain
Length = 263
Score = 56.2 bits (134), Expect = 5e-08
Identities = 74/281 (26%), Positives = 114/281 (40%), Gaps = 68/281 (24%)
Query: 40 ISFVVYQFILY-------PFVVPKLNEWFFKEHYTERDEPDKINFDIHTVSMIQSVV--- 89
ISF +Q + Y V P N FK+ KI ++ VS S+V
Sbjct: 14 ISFFTFQLLFYFVSYWFSAKVSPGFNSLSFKK---------KIEWNSRVVSTCHSLVVGI 64
Query: 90 -SLYLIWPLLWIPFGFNVATYYN------SYASMVSAVSIGYFMWDLYICLRYFKLFGIG 142
LY+ F F+ AT + S A++ A++ GY + DL I + Y+K+ G
Sbjct: 65 FGLYI--------FLFDEATKADPLWGGPSLANVNIAIASGYLISDLSIIILYWKVIGDK 116
Query: 143 XXXXXX-XXXXXXTITLHPVCQAWIGRF-LSFEASTPFVNINWYIIQLSRGSSKQVVPTW 200
+ L A+IG F L E S+PFVN W+ L + +
Sbjct: 117 FFIMHHCASLYAYYLVLKNGVLAYIGNFRLLAELSSPFVNQRWFFEALKYPKFSKAI--- 173
Query: 201 FNVLNGFLLISVFFFVRLV-----WGFVAVAILIYEMWQVWDQIPLYMTAVILGIN---- 251
V+NG L+ VFF VR+ +GF M+ V+ P V++ ++
Sbjct: 174 --VINGILMTVVFFIVRIASMLPHYGF---------MYSVYGTEPYIRLGVLIQLSWVIS 222
Query: 252 -VSLDFLNIHWFSKMLK--------IAKKMANGSKRVSKID 283
V LD +N+ W K+ K I ++ A S + K+D
Sbjct: 223 CVVLDVMNVMWMIKISKGCIKVISHIRQEKAKNSLQNGKLD 263
>At1g31300 [TR] KOG4561 Uncharacterized conserved protein contains TBC domain
Length = 278
Score = 49.3 bits (116), Expect = 6e-06
Identities = 54/208 (25%), Positives = 90/208 (42%), Gaps = 25/208 (12%)
Query: 76 NFDIHTVSMIQ-SVVSLYLI-WPLLWIPFGFNVATYYNS--YASMVSAVSIGYFMWDL-Y 130
N I TV I S +SLY + W L+ N + S +S+ +SIGYF+ DL
Sbjct: 76 NRGISTVHAIFISAMSLYFVFWSDLFSDRWHNDLVVFRSSRLSSLGLGISIGYFLADLGM 135
Query: 131 ICLRYFKLFGIGXXXXXXXXXXXXTITLHP-VCQAWIGRFLSFEASTPFVNINWYIIQLS 189
I +Y L GI +L Q + L E +TP +N+ WY+ +
Sbjct: 136 IFWKYPSLGGIEYIVHHSLSGVAVAYSLFSGEGQLYTYMVLISEITTPEINLRWYLD--T 193
Query: 190 RGSSKQVVPTWFNVLNGFLLISVFFFVRLVWGFVAVAILIYEMWQVW------DQIPLYM 243
G K + V+NG F+ L W + + IY + V+ ++ ++
Sbjct: 194 AGMKKSLA----YVVNG-------VFIFLAWLVARILLFIYMFYHVYLHYNQVMRMHIFG 242
Query: 244 TAVILGINVSLDFLNIHWFSKMLKIAKK 271
++ G+ +L +N+ WF K+++ KK
Sbjct: 243 YVLVFGVPAALGVMNLIWFGKIVRGVKK 270
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.329 0.143 0.469
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,260,331
Number of Sequences: 60738
Number of extensions: 632358
Number of successful extensions: 1814
Number of sequences better than 1.0e-05: 5
Number of HSP's better than 0.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 1798
Number of HSP's gapped (non-prelim): 5
length of query: 283
length of database: 30,389,216
effective HSP length: 105
effective length of query: 178
effective length of database: 24,011,726
effective search space: 4274087228
effective search space used: 4274087228
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.8 bits)