ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIV2777 check: MH T KOG1165 Signal transduction mechanisms Casein kinase (serine/threonine/tyrosine protein kinase)
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIV2777 944068 942461 -536
(536 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YNL154c [T] KOG1165 Casein kinase (serine/threonine/tyrosine pro... 631 0.0
YHR135c [T] KOG1165 Casein kinase (serine/threonine/tyrosine pro... 614 e-175
SPBP35G2.05c [T] KOG1165 Casein kinase (serine/threonine/tyrosin... 449 e-126
SPBC1347.06c [T] KOG1165 Casein kinase (serine/threonine/tyrosin... 442 e-124
YER123w [T] KOG1165 Casein kinase (serine/threonine/tyrosine pro... 439 e-123
SPAC1805.05 [T] KOG1165 Casein kinase (serine/threonine/tyrosine... 422 e-118
HsM5579454 [T] KOG1165 Casein kinase (serine/threonine/tyrosine ... 354 2e-97
Hs21314778 [T] KOG1165 Casein kinase (serine/threonine/tyrosine ... 354 2e-97
Hs4758080 [T] KOG1165 Casein kinase (serine/threonine/tyrosine p... 349 7e-96
7300125 [T] KOG1165 Casein kinase (serine/threonine/tyrosine pro... 344 2e-94
CE29604 [T] KOG1165 Casein kinase (serine/threonine/tyrosine pro... 340 3e-93
Hs11545751 [T] KOG1165 Casein kinase (serine/threonine/tyrosine ... 338 2e-92
Hs19923746 [T] KOG1163 Casein kinase (serine/threonine/tyrosine ... 312 7e-85
At3g23340 [T] KOG1164 Casein kinase (serine/threonine/tyrosine p... 309 8e-84
Hs4503093 [T] KOG1164 Casein kinase (serine/threonine/tyrosine p... 308 1e-83
Hs21624639 [T] KOG1163 Casein kinase (serine/threonine/tyrosine ... 308 1e-83
At5g43320 [T] KOG1164 Casein kinase (serine/threonine/tyrosine p... 308 1e-83
SPBC3H7.15 [T] KOG1164 Casein kinase (serine/threonine/tyrosine ... 308 2e-83
Hs17475657 [T] KOG1163 Casein kinase (serine/threonine/tyrosine ... 307 3e-83
At2g19470 [T] KOG1164 Casein kinase (serine/threonine/tyrosine p... 306 4e-83
YPL204w [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 306 7e-83
CE00872 [T] KOG1163 Casein kinase (serine/threonine/tyrosine pro... 306 7e-83
At4g14340 [T] KOG1164 Casein kinase (serine/threonine/tyrosine p... 306 7e-83
At1g04440 [T] KOG1164 Casein kinase (serine/threonine/tyrosine p... 306 7e-83
Hs20544145 [T] KOG1164 Casein kinase (serine/threonine/tyrosine ... 305 9e-83
Hs20149530 [T] KOG1164 Casein kinase (serine/threonine/tyrosine ... 305 9e-83
At1g72710 [T] KOG1164 Casein kinase (serine/threonine/tyrosine p... 305 1e-82
7302004 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 305 1e-82
At4g26100 [T] KOG1164 Casein kinase (serine/threonine/tyrosine p... 303 4e-82
At4g28540 [T] KOG1164 Casein kinase (serine/threonine/tyrosine p... 301 1e-81
CE05879 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 299 6e-81
At1g03930 [T] KOG1164 Casein kinase (serine/threonine/tyrosine p... 298 1e-80
At5g44100 [T] KOG1164 Casein kinase (serine/threonine/tyrosine p... 298 2e-80
At4g28880 [T] KOG1164 Casein kinase (serine/threonine/tyrosine p... 296 7e-80
At4g28860 [T] KOG1164 Casein kinase (serine/threonine/tyrosine p... 294 2e-79
SPAC23C4.12 [T] KOG1164 Casein kinase (serine/threonine/tyrosine... 293 4e-79
7292798 [T] KOG1163 Casein kinase (serine/threonine/tyrosine pro... 286 7e-77
7292762 [T] KOG1163 Casein kinase (serine/threonine/tyrosine pro... 251 1e-66
ECU03g0910 [T] KOG1164 Casein kinase (serine/threonine/tyrosine ... 246 8e-65
At4g08800 [T] KOG1164 Casein kinase (serine/threonine/tyrosine p... 243 7e-64
7296752 [T] KOG1163 Casein kinase (serine/threonine/tyrosine pro... 242 9e-64
7295933 [T] KOG1163 Casein kinase (serine/threonine/tyrosine pro... 229 8e-60
7298405 [T] KOG1163 Casein kinase (serine/threonine/tyrosine pro... 214 3e-55
At2g25760 [T] KOG1164 Casein kinase (serine/threonine/tyrosine p... 192 8e-49
At5g18190 [T] KOG1164 Casein kinase (serine/threonine/tyrosine p... 185 1e-46
At3g13670 [T] KOG1164 Casein kinase (serine/threonine/tyrosine p... 184 3e-46
At3g03940 [T] KOG1164 Casein kinase (serine/threonine/tyrosine p... 176 8e-44
CE06325 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 151 2e-36
ECU11g1980 [T] KOG1164 Casein kinase (serine/threonine/tyrosine ... 143 6e-34
Hs4507903 [T] KOG1164 Casein kinase (serine/threonine/tyrosine p... 135 2e-31
CE09021 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 127 4e-29
CE16557 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 127 6e-29
CE08953 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 121 2e-27
CE25045 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 120 5e-27
CE01965 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 120 5e-27
CE29490 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 119 1e-26
CE14562 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 119 1e-26
CE03499 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 118 3e-26
CE02210 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 118 3e-26
CE01289 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 117 4e-26
CE06942 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 115 2e-25
CE18365 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 115 2e-25
Hs20555151 [T] KOG1164 Casein kinase (serine/threonine/tyrosine ... 114 3e-25
CE22097 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 114 5e-25
CE02312 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 114 5e-25
CE28799 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 112 1e-24
CE08640 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 111 3e-24
CE05253 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 111 3e-24
CE06632 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 110 4e-24
CE05474 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 110 7e-24
CE06688 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 108 2e-23
7304307 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 107 6e-23
CE04522 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 106 1e-22
CE20743 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 105 2e-22
CE02393 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 103 9e-22
CE02142 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 102 1e-21
CE14744 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 102 1e-21
CE01982 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 102 1e-21
CE03754 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 101 2e-21
CE19439 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 100 4e-21
CE18539 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 100 4e-21
CE15320 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 100 6e-21
CE06796 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 100 6e-21
CE15237 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 99 2e-20
CE13469 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 99 2e-20
CE12108 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 99 2e-20
Hs5454164 [T] KOG1164 Casein kinase (serine/threonine/tyrosine p... 99 2e-20
CE27672 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 97 5e-20
CE09980 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 97 5e-20
CE07450 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 97 5e-20
CE05212 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 97 5e-20
CE04892 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 96 2e-19
CE00935 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 96 2e-19
CE09979 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 95 2e-19
CE07449 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 95 2e-19
CE15314 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 94 4e-19
CE04980 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 94 4e-19
CE19741 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 93 1e-18
CE22732 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 92 2e-18
CE20236 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 91 4e-18
CE12416 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 91 4e-18
CE16168 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 91 6e-18
CE17237 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 89 1e-17
CE09897 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 89 2e-17
CE00873 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 89 2e-17
CE16891 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 87 8e-17
CE24572 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 83 9e-16
CE02965 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 80 1e-14
CE02499 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 79 1e-14
CE24727 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 79 2e-14
CE17143 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 78 3e-14
CE07685 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 78 3e-14
CE01404 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 78 3e-14
CE24851 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 78 4e-14
CE12690 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 77 9e-14
CE03487 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 76 1e-13
At5g66210 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 74 6e-13
Hs7705993 [T] KOG1164 Casein kinase (serine/threonine/tyrosine p... 72 2e-12
CE04290 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 72 2e-12
Hs4759052 [T] KOG0603 Ribosomal protein S6 kinase 72 2e-12
YDR490c [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 70 6e-12
CE29038 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 70 6e-12
7303521 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 70 6e-12
CE09428 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 70 1e-11
At2g46700 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 69 1e-11
CE04444 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 69 2e-11
SPCC576.15c [T] KOG0592 3-phosphoinositide-dependent protein kin... 68 4e-11
CE24636 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 68 4e-11
CE02704 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 67 7e-11
At3g50530 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 66 2e-10
CE18967 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD a... 65 2e-10
CE02376 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 65 2e-10
At3g19100 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 65 3e-10
CE05552 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 64 4e-10
CE24516 [OUT] KOG0595 Serine/threonine-protein kinase involved i... 64 7e-10
SPCC320.12c [D] KOG0580 Serine/threonine protein kinase 63 1e-09
YDR466w [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 63 1e-09
CE07205 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 63 1e-09
CE07204 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 63 1e-09
At3g56760 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 63 1e-09
SPBC18H10.15 [R] KOG0663 Protein kinase PITSLRE and related kinases 62 2e-09
At4g21940 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 62 2e-09
At1g09000 [T] KOG0198 MEKK and related serine/threonine protein ... 62 2e-09
At1g54960 [T] KOG0198 MEKK and related serine/threonine protein ... 62 2e-09
7302202 [D] KOG1166 Mitotic checkpoint serine/threonine protein ... 62 2e-09
CE05507 [T] KOG0603 Ribosomal protein S6 kinase 62 3e-09
CE03889 [T] KOG1345 Serine/threonine kinase 62 3e-09
Hs6031180 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and... 61 4e-09
Hs5803088 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and... 61 4e-09
CE25557 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 61 4e-09
CE08836 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 61 4e-09
At2g17890 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 61 4e-09
YJL095w [T] KOG0198 MEKK and related serine/threonine protein ki... 61 5e-09
SPACUNK12.02c [T] KOG0032 Ca2+/calmodulin-dependent protein kina... 60 6e-09
Hs4505811 [T] KOG0583 Serine/threonine protein kinase 60 6e-09
At5g24430 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 60 6e-09
At4g36070 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 60 6e-09
At2g41140 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 60 6e-09
Hs4507831 [OUT] KOG0595 Serine/threonine-protein kinase involved... 60 8e-09
CE18169 [T] KOG0603 Ribosomal protein S6 kinase 60 8e-09
CE13014 [T] KOG0603 Ribosomal protein S6 kinase 60 8e-09
CE29300 [T] KOG0694 Serine/threonine protein kinase 60 1e-08
CE29299 [T] KOG0694 Serine/threonine protein kinase 60 1e-08
At1g49580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 60 1e-08
YGL158w [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 59 1e-08
SPAC9G1.02 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 an... 59 1e-08
At1g50230 [R] KOG0597 Serine-threonine protein kinase FUSED 59 2e-08
7297611 [T] KOG0614 cGMP-dependent protein kinase 59 2e-08
YOL100w [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 59 2e-08
HsM7657627 [D] KOG0575 Polo-like serine/threonine protein kinase 59 2e-08
Hs4507719 [D] KOG0596 Dual specificity; serine/threonine and tyr... 59 2e-08
Hs4505695 [T] KOG0592 3-phosphoinositide-dependent protein kinas... 59 2e-08
Hs20547712 [D] KOG0596 Dual specificity; serine/threonine and ty... 59 2e-08
CE20142 [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 59 2e-08
YCR073c [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and r... 58 3e-08
SPBC4C3.11 [T] KOG0592 3-phosphoinositide-dependent protein kina... 58 3e-08
Hs5174547 [T] KOG4279 Serine/threonine protein kinase 58 3e-08
CE26076 [D] KOG0590 Checkpoint kinase and related serine/threoni... 58 3e-08
At3g49370 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 58 4e-08
YPL209c [D] KOG0580 Serine/threonine protein kinase 57 5e-08
Hs21361433 [D] KOG0575 Polo-like serine/threonine protein kinase 57 5e-08
Hs4759050 [T] KOG0603 Ribosomal protein S6 kinase 57 7e-08
Hs20149547 [T] KOG0603 Ribosomal protein S6 kinase 57 7e-08
At5g50180 [T] KOG0192 Tyrosine kinase specific for activated (GT... 57 7e-08
At1g76040 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 57 7e-08
Hs7657526 [T] KOG0603 Ribosomal protein S6 kinase 57 9e-08
Hs5730055 [D] KOG0575 Polo-like serine/threonine protein kinase 57 9e-08
Hs14042966 [T] KOG0583 Serine/threonine protein kinase 57 9e-08
7295431 [D] KOG0601 Cyclin-dependent kinase WEE1 57 9e-08
Hs4758652 [R] KOG0593 Predicted protein kinase KKIAMRE 56 1e-07
Hs20479818 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 56 1e-07
CE24761 [D] KOG0580 Serine/threonine protein kinase 56 1e-07
7302570 [R] KOG0586 Serine/threonine protein kinase 56 1e-07
7300559 [T] KOG4279 Serine/threonine protein kinase 56 1e-07
Hs18552621 [R] KOG0597 Serine-threonine protein kinase FUSED 56 2e-07
ECU07g0360 [D] KOG0580 Serine/threonine protein kinase 56 2e-07
At4g23650 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 56 2e-07
At3g27560 [T] KOG0192 Tyrosine kinase specific for activated (GT... 56 2e-07
At3g06030 [T] KOG0198 MEKK and related serine/threonine protein ... 56 2e-07
At2g31500 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 56 2e-07
At1g61950 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 56 2e-07
At3g61960 [OUT] KOG0595 Serine/threonine-protein kinase involved... 55 2e-07
At2g35890 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 55 2e-07
YOR061w [TDK] KOG0668 Casein kinase II alpha subunit 55 3e-07
SPBC8D2.19 [T] KOG0661 MAPK related serine/threonine protein kinase 55 3e-07
Hs22068996 [T] KOG1345 Serine/threonine kinase 55 3e-07
7298698 [T] KOG4250 TANK binding protein kinase TBK1 55 3e-07
Hs4506735 [T] KOG0603 Ribosomal protein S6 kinase 55 3e-07
ECU07g0520 [T] KOG0616 cAMP-dependent protein kinase catalytic s... 55 3e-07
At4g04720 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 55 3e-07
At3g20410 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 55 3e-07
At2g38910 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 55 3e-07
YHR205w [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 54 5e-07
Hs4826948 [T] KOG0616 cAMP-dependent protein kinase catalytic su... 54 5e-07
At2g34290 [T] KOG0198 MEKK and related serine/threonine protein ... 54 5e-07
At5g55090 [T] KOG0198 MEKK and related serine/threonine protein ... 54 6e-07
At4g35780 [T] KOG0192 Tyrosine kinase specific for activated (GT... 54 6e-07
7300435 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and r... 54 6e-07
7298323 [D] KOG0590 Checkpoint kinase and related serine/threoni... 54 6e-07
Hs8923754 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 54 8e-07
Hs10835065 [T] KOG0616 cAMP-dependent protein kinase catalytic s... 54 8e-07
CE17284 [T] KOG0583 Serine/threonine protein kinase 54 8e-07
CE12478 [D] KOG0590 Checkpoint kinase and related serine/threoni... 54 8e-07
Hs8393810_1 [T] KOG0587 Traf2- and Nck-interacting kinase and re... 54 8e-07
Hs20544910_1 [T] KOG0587 Traf2- and Nck-interacting kinase and r... 54 8e-07
SPBC106.10 [T] KOG0616 cAMP-dependent protein kinase catalytic s... 53 1e-06
Hs19923570 [T] KOG0603 Ribosomal protein S6 kinase 53 1e-06
CE28218 [D] KOG0588 Serine/threonine protein kinase 53 1e-06
CE20258 [R] KOG0593 Predicted protein kinase KKIAMRE 53 1e-06
Hs4502803 [D] KOG0590 Checkpoint kinase and related serine/threo... 53 1e-06
CE06635 [Z] KOG0613 Projectin/twitchin and related proteins 53 1e-06
CE06634 [Z] KOG0613 Projectin/twitchin and related proteins 53 1e-06
At2g17290 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 53 1e-06
YBR028c [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 52 2e-06
CE28744 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 52 2e-06
CE28571 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 52 2e-06
CE27220 [T] KOG0660 Mitogen-activated protein kinase 52 2e-06
CE26649 [D] KOG0575 Polo-like serine/threonine protein kinase 52 2e-06
At3g57530 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 52 2e-06
At3g06620 [T] KOG0192 Tyrosine kinase specific for activated (GT... 52 2e-06
7302199 [T] KOG0197 Tyrosine kinases 52 2e-06
YPL203w [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 52 2e-06
YFR014c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 52 2e-06
Hs20545245 [D] KOG0588 Serine/threonine protein kinase 52 2e-06
Hs19923468 [T] KOG4236 Serine/threonine protein kinase PKC mu/PK... 52 2e-06
ECU10g0120 [L] KOG1167 Serine/threonine protein kinase of the CD... 52 2e-06
ECU08g1960 [L] KOG1167 Serine/threonine protein kinase of the CD... 52 2e-06
CE06762 [T] KOG0660 Mitogen-activated protein kinase 52 2e-06
CE04173 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 52 2e-06
CE02377 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 52 2e-06
At4g04700 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 52 2e-06
At2g41860 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 52 2e-06
At1g50700 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 52 2e-06
7300551 [T] KOG1027 Serine/threonine protein kinase and endoribo... 52 2e-06
7299536 [D] KOG0580 Serine/threonine protein kinase 52 2e-06
7292519 [T] KOG0197 Tyrosine kinases 52 2e-06
Hs19923407 [D] KOG0591 NIMA (never in mitosis)-related G2-specif... 52 3e-06
ECU08g1480 [R] KOG0586 Serine/threonine protein kinase 52 3e-06
At4g28980 [R] KOG0594 Protein kinase PCTAIRE and related kinases 52 3e-06
At3g53570 [T] KOG0671 LAMMER dual specificity kinases 52 3e-06
YPL153c [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 51 4e-06
YOL016c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 51 4e-06
CE28168 [T] KOG0194 Protein tyrosine kinase 51 4e-06
At5g40540 [T] KOG0192 Tyrosine kinase specific for activated (GT... 51 4e-06
At5g19450 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 51 4e-06
At5g12180 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 51 4e-06
At4g35310 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 51 4e-06
At3g04530 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 51 4e-06
7295638 [T] KOG0603 Ribosomal protein S6 kinase 51 4e-06
SPCC777.14 [A] KOG0670 U4/U6-associated splicing factor PRP4 51 5e-06
SPAC890.03 [T] KOG0583 Serine/threonine protein kinase 51 5e-06
CE03492 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 51 5e-06
At5g19360 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 51 5e-06
At3g08730 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 51 5e-06
7302861 [T] KOG0696 Serine/threonine protein kinase 51 5e-06
7300437 [TR] KOG0606 Microtubule-associated serine/threonine kin... 51 5e-06
7291910 [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 51 5e-06
SPCC74.03c [T] KOG0583 Serine/threonine protein kinase 50 7e-06
Hs5031689 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD... 50 7e-06
Hs20070158 [T] KOG0201 Serine/threonine protein kinase 50 7e-06
Hs18250298 [T] KOG0197 Tyrosine kinases 50 7e-06
Hs15011880 [T] KOG0201 Serine/threonine protein kinase 50 7e-06
At5g58940 [T] KOG1187 Serine/threonine protein kinase 50 7e-06
At3g08720 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 50 7e-06
At3g06630 [T] KOG0192 Tyrosine kinase specific for activated (GT... 50 7e-06
At2g11520 [T] KOG1187 Serine/threonine protein kinase 50 7e-06
At1g12680 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 50 7e-06
7290249 [R] KOG0586 Serine/threonine protein kinase 50 7e-06
Hs4758702 [T] KOG4279 Serine/threonine protein kinase 50 9e-06
Hs4506529 [T] KOG0986 G protein-coupled receptor kinase 50 9e-06
Hs14249562 [TR] KOG0606 Microtubule-associated serine/threonine ... 50 9e-06
CE03584 [T] KOG0607 MAP kinase-interacting kinase and related se... 50 9e-06
At3g06640 [T] KOG0192 Tyrosine kinase specific for activated (GT... 50 9e-06
At1g74740 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 50 9e-06
>YNL154c [T] KOG1165 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 546
Score = 631 bits (1627), Expect = 0.0
Identities = 330/551 (59%), Positives = 360/551 (64%), Gaps = 20/551 (3%)
Query: 1 MSITAGPKVTTTAALVNTDRKMN----NHHSTQVLHGSGQHGMQPSXXXXXXXXXXXXXX 56
MS P T + L + MN N + ++++G+ P
Sbjct: 1 MSQVQSPLTATNSGLAVNNNTMNSQMPNRSNVRLVNGT-----LPPSLHVSSNLNHNTGN 55
Query: 57 XQXXXXXXXXXXXXXIVGLHYKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPRKTDAPQ 116
IVGLHYKIGKKIGEGSFGVLFEG NMIN +PVAIKFEPRKT+APQ
Sbjct: 56 SSASYSGSQSRDDSTIVGLHYKIGKKIGEGSFGVLFEGTNMINGLPVAIKFEPRKTEAPQ 115
Query: 117 LKDEYRTYKILSGSEGIPQAYYFGQEGLHNILVIDLLGPSLEDLFDWCGRRFSIKTVVHV 176
LKDEYRTYKIL+G+ GIPQ YYFGQEGLHNILVIDLLGPSLEDLFDWCGRRFS+KTVV V
Sbjct: 116 LKDEYRTYKILAGTPGIPQEYYFGQEGLHNILVIDLLGPSLEDLFDWCGRRFSVKTVVQV 175
Query: 177 AIQMITLIEELHDHDLIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIP 236
A+QMITLIE+LH HDLIYRDIKPDNFLIGRP QPDAN VHLIDFGMAK YRDPKTKQHIP
Sbjct: 176 AVQMITLIEDLHAHDLIYRDIKPDNFLIGRPGQPDANKVHLIDFGMAKQYRDPKTKQHIP 235
Query: 237 YREKKSLSGTARYMSINTHLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKAANNKLKYE 296
YREKKSLSGTARYMSINTHLGREQSRRDDMEA+GHVFFYFLRGQLPWQGLKA NNK KYE
Sbjct: 236 YREKKSLSGTARYMSINTHLGREQSRRDDMEAMGHVFFYFLRGQLPWQGLKAPNNKQKYE 295
Query: 297 KIGEKKRSTNVYDLSQGLPVQFGRYLEIVRNLGFEETPDYEGYRKLLLSVLDELGQKLDG 356
KIGEKKR TNVYDL+QGLP+QFGRYLEIVRNL FEETPDYEGYR LLLSVLD+LG+ DG
Sbjct: 296 KIGEKKRLTNVYDLAQGLPIQFGRYLEIVRNLSFEETPDYEGYRMLLLSVLDDLGETADG 355
Query: 357 EYDWMKLNGGRGWDLAINKKPNLHGYGHPTPPNEKSKRHRNKFNQV--PLAVNNLNGSNV 414
+YDWMKLNGGRGWDL+INKKPNLHGYGHP PPNEKSKRHR+K +Q P ++ N
Sbjct: 356 QYDWMKLNGGRGWDLSINKKPNLHGYGHPNPPNEKSKRHRSKNHQYSSPDHHHHYNQQQQ 415
Query: 415 PLQSHSPLPGGTDL---------TQGVSNAPXXXXXXXXXXXXXXXXXXRLDPMSYEXXX 465
Q+ + Q A +LDP SYE
Sbjct: 416 QQQAQAQAQAQAQAKVQQQQLQQAQAQQQANRYQLQPDDSHYDEEREASKLDPTSYEAYQ 475
Query: 466 XXXXXXXXXXXXXXXXXXXXXXNNDTXXXXXXXXXXXXXXXXXXXXXXXNGKVQVADSNS 525
N N + S
Sbjct: 476 QQTQQKYAQQQQKQMQQKSKQFANTGANGQTNKYPYNAQPTANDEQNAKNAAQDRNSNKS 535
Query: 526 EKGFFSKLGCC 536
KGFFSKLGCC
Sbjct: 536 SKGFFSKLGCC 546
>YHR135c [T] KOG1165 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 538
Score = 614 bits (1583), Expect = e-175
Identities = 290/327 (88%), Positives = 307/327 (93%)
Query: 72 IVGLHYKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPRKTDAPQLKDEYRTYKILSGSE 131
IVGLHYKIGKKIGEGSFGVLFEG NMIN VPVAIKFEPRKT+APQL+DEY+TYKIL+G+
Sbjct: 64 IVGLHYKIGKKIGEGSFGVLFEGTNMINGVPVAIKFEPRKTEAPQLRDEYKTYKILNGTP 123
Query: 132 GIPQAYYFGQEGLHNILVIDLLGPSLEDLFDWCGRRFSIKTVVHVAIQMITLIEELHDHD 191
IP AYYFGQEGLHNILVIDLLGPSLEDLFDWCGR+FS+KTVV VA+QMITLIE+LH HD
Sbjct: 124 NIPYAYYFGQEGLHNILVIDLLGPSLEDLFDWCGRKFSVKTVVQVAVQMITLIEDLHAHD 183
Query: 192 LIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTARYMS 251
LIYRDIKPDNFLIGRP QPDAN +HLIDFGMAK YRDPKTKQHIPYREKKSLSGTARYMS
Sbjct: 184 LIYRDIKPDNFLIGRPGQPDANNIHLIDFGMAKQYRDPKTKQHIPYREKKSLSGTARYMS 243
Query: 252 INTHLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKAANNKLKYEKIGEKKRSTNVYDLS 311
INTHLGREQSRRDDMEALGHVFFYFLRG LPWQGLKA NNK KYEKIGEKKRSTNVYDL+
Sbjct: 244 INTHLGREQSRRDDMEALGHVFFYFLRGHLPWQGLKAPNNKQKYEKIGEKKRSTNVYDLA 303
Query: 312 QGLPVQFGRYLEIVRNLGFEETPDYEGYRKLLLSVLDELGQKLDGEYDWMKLNGGRGWDL 371
QGLPVQFGRYLEIVR+L FEE PDYEGYRKLLLSVLD+LG+ DG+YDWMKLN GRGWDL
Sbjct: 304 QGLPVQFGRYLEIVRSLSFEECPDYEGYRKLLLSVLDDLGETADGQYDWMKLNDGRGWDL 363
Query: 372 AINKKPNLHGYGHPTPPNEKSKRHRNK 398
INKKPNLHGYGHP PPNEKS++HRNK
Sbjct: 364 NINKKPNLHGYGHPNPPNEKSRKHRNK 390
>SPBP35G2.05c [T] KOG1165 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 435
Score = 449 bits (1154), Expect = e-126
Identities = 205/299 (68%), Positives = 253/299 (84%)
Query: 72 IVGLHYKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPRKTDAPQLKDEYRTYKILSGSE 131
+VG+HY++G+KIGEGSFGV+F+G+N++NN +AIKFEP+K++APQL+DEYRTYK+L G+
Sbjct: 7 VVGVHYRVGRKIGEGSFGVIFDGMNLLNNQLIAIKFEPKKSEAPQLRDEYRTYKLLVGNA 66
Query: 132 GIPQAYYFGQEGLHNILVIDLLGPSLEDLFDWCGRRFSIKTVVHVAIQMITLIEELHDHD 191
GIP YYFGQEGLHNILVIDLLGPSLEDLF+WCGRRFS+KTV A QM++ ++ +H+ +
Sbjct: 67 GIPNVYYFGQEGLHNILVIDLLGPSLEDLFEWCGRRFSVKTVAMTAKQMLSRVQTIHEKN 126
Query: 192 LIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTARYMS 251
L+YRDIKPDNFLIGRP+ +ANMV+++DFGMAK YRDPKTKQHIPY E+KSLSGTARYMS
Sbjct: 127 LVYRDIKPDNFLIGRPSSRNANMVYMVDFGMAKYYRDPKTKQHIPYSERKSLSGTARYMS 186
Query: 252 INTHLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKAANNKLKYEKIGEKKRSTNVYDLS 311
INTHLGREQSRRDD+E+LGHVF YFLRG LPWQGLKAANNK KYEKI EKK+ST++ +L
Sbjct: 187 INTHLGREQSRRDDLESLGHVFMYFLRGSLPWQGLKAANNKHKYEKISEKKQSTSISELC 246
Query: 312 QGLPVQFGRYLEIVRNLGFEETPDYEGYRKLLLSVLDELGQKLDGEYDWMKLNGGRGWD 370
G P +F +Y+ VR+L F+E PDY ++L VL G DG YDWM LN G+GW+
Sbjct: 247 AGFPNEFSKYMTYVRSLEFDEEPDYAFLQELFDDVLRANGDTNDGVYDWMLLNDGKGWE 305
>SPBC1347.06c [T] KOG1165 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 446
Score = 442 bits (1137), Expect = e-124
Identities = 205/320 (64%), Positives = 248/320 (77%)
Query: 72 IVGLHYKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPRKTDAPQLKDEYRTYKILSGSE 131
+VG+HYK+G++IGEGSFGV+FEG N++NN VAIKFEPR++DAPQL+DEYRTYK+L+G
Sbjct: 7 VVGVHYKVGRRIGEGSFGVIFEGTNLLNNQQVAIKFEPRRSDAPQLRDEYRTYKLLAGCT 66
Query: 132 GIPQAYYFGQEGLHNILVIDLLGPSLEDLFDWCGRRFSIKTVVHVAIQMITLIEELHDHD 191
GIP YYFGQEGLHNILVIDLLGPSLEDL D CGR+FS+KTV A QM+ ++ +H+
Sbjct: 67 GIPNVYYFGQEGLHNILVIDLLGPSLEDLLDLCGRKFSVKTVAMAAKQMLARVQSIHEKS 126
Query: 192 LIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTARYMS 251
L+YRDIKPDNFLIGRPN +ANM++++DFGM K YRDP TKQHIPYREKK+LSGTARYMS
Sbjct: 127 LVYRDIKPDNFLIGRPNSKNANMIYVVDFGMVKFYRDPVTKQHIPYREKKNLSGTARYMS 186
Query: 252 INTHLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKAANNKLKYEKIGEKKRSTNVYDLS 311
INTHLGREQSRRDD+EALGHVF YFLRG LPWQGLKAA NK KYE+IGEKK+ST + +L
Sbjct: 187 INTHLGREQSRRDDLEALGHVFMYFLRGSLPWQGLKAATNKQKYERIGEKKQSTPLRELC 246
Query: 312 QGLPVQFGRYLEIVRNLGFEETPDYEGYRKLLLSVLDELGQKLDGEYDWMKLNGGRGWDL 371
G P +F +Y+ RNL F+ TPDY+ + L VL+ L D +DW LN G+GW
Sbjct: 247 AGFPEEFYKYMHYARNLAFDATPDYDYLQGLFSKVLERLNTTEDENFDWNLLNNGKGWQS 306
Query: 372 AINKKPNLHGYGHPTPPNEK 391
++ PP K
Sbjct: 307 LKSRNAETENQRSSKPPAPK 326
>YER123w [T] KOG1165 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 524
Score = 439 bits (1128), Expect = e-123
Identities = 214/351 (60%), Positives = 257/351 (72%), Gaps = 35/351 (9%)
Query: 72 IVGLHYKIGKKIGEGSFGVLFEGVNMIN-----------------NVPVAIKFEPRKTDA 114
IVG+HY +G KIGEGSFGV+FEG N+++ N PVAIKFEPR +DA
Sbjct: 9 IVGIHYAVGPKIGEGSFGVIFEGENILHSCQAQTGSKRDSSIIMANEPVAIKFEPRHSDA 68
Query: 115 PQLKDEYRTYKILSGSEGIPQAYYFGQEGLHNILVIDLLGPSLEDLFDWCGRRFSIKTVV 174
PQL+DE+R Y+IL+G GIP AYYFGQEG+HNIL+IDLLGPSLEDLF+WCGR+FS+KT
Sbjct: 69 PQLRDEFRAYRILNGCVGIPHAYYFGQEGMHNILIIDLLGPSLEDLFEWCGRKFSVKTTC 128
Query: 175 HVAIQMITLIEELHDHDLIYRDIKPDNFLIGR----------------PNQPDANMVHLI 218
VA QMI + +HDHDLIYRDIKPDNFLI + + D N+++++
Sbjct: 129 MVAKQMIDRVRAIHDHDLIYRDIKPDNFLISQYQRISPEGKVIKSCASSSNNDPNLIYMV 188
Query: 219 DFGMAKLYRDPKTKQHIPYREKKSLSGTARYMSINTHLGREQSRRDDMEALGHVFFYFLR 278
DFGMAK YRDP+TKQHIPYRE+KSLSGTARYMSINTH GREQSRRDD+E+LGHVFFYFLR
Sbjct: 189 DFGMAKQYRDPRTKQHIPYRERKSLSGTARYMSINTHFGREQSRRDDLESLGHVFFYFLR 248
Query: 279 GQLPWQGLKAANNKLKYEKIGEKKRSTNVYD--LSQGLPVQFGRYLEIVRNLGFEETPDY 336
G LPWQGLKA NNKLKYEKIG K+ N D L+ +P QF YL+ R+L F+E PDY
Sbjct: 249 GSLPWQGLKAPNNKLKYEKIGMTKQKLNPDDLLLNNAIPYQFATYLKYARSLKFDEDPDY 308
Query: 337 EGYRKLLLSVLDELGQKLDGEYDWMKLNGGRGWDLAINKKPNLHGYGHPTP 387
+ L+ L K DG YDWM LNGG+GW++ IN++ NLHGYG+P P
Sbjct: 309 DYLISLMDDALRLNDLKDDGHYDWMDLNGGKGWNIKINRRANLHGYGNPNP 359
>SPAC1805.05 [T] KOG1165 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 439
Score = 422 bits (1085), Expect = e-118
Identities = 207/362 (57%), Positives = 262/362 (72%), Gaps = 10/362 (2%)
Query: 72 IVGLHYKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPRKTDAPQLKDEYRTYKILSGSE 131
+VG+HY++GKKIGEGSFG+LF+GVN+INN P+A+KFE RK++ PQL+DEY TYK+L G
Sbjct: 10 VVGVHYRVGKKIGEGSFGMLFQGVNLINNQPIALKFESRKSEVPQLRDEYLTYKLLMGLP 69
Query: 132 GIPQAYYFGQEGLHNILVIDLLGPSLEDLFDWCGRRFSIKTVVHVAIQMITLIEELHDHD 191
GIP YY+GQEG++N+LV+DLLGPSLEDLFD+CGRRFS KTV +A QMIT I+ +H+
Sbjct: 70 GIPSVYYYGQEGMYNLLVMDLLGPSLEDLFDYCGRRFSPKTVAMIAKQMITRIQSVHERH 129
Query: 192 LIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTARYMS 251
IYRDIKPDNFLIG P N+++ +DFGMAK YRDPKT H PY E KSLSGTARYMS
Sbjct: 130 FIYRDIKPDNFLIGFPGSKTENVIYAVDFGMAKQYRDPKTHVHRPYNEHKSLSGTARYMS 189
Query: 252 INTHLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKAANNKLKYEKIGEKKRSTNVYDLS 311
INTHLGREQSRRDD+E++GHVF YFLRG LPWQGLKAA NK KYEKIGEKK+ T + +L
Sbjct: 190 INTHLGREQSRRDDLESMGHVFMYFLRGSLPWQGLKAATNKQKYEKIGEKKQVTPLKELC 249
Query: 312 QGLPVQFGRYLEIVRNLGFEETPDYEGYRKLLLSVLDELGQKLDGEYDWMKLNGGRGWDL 371
+G P +F +Y+ RNLG+EE PDY+ R L S+L + + DG+YDW LN G+GW
Sbjct: 250 EGYPKEFLQYMIYARNLGYEEAPDYDYLRSLFDSLLLRINETDDGKYDWTLLNNGKGWQY 309
Query: 372 AINKK---PNLHGYG------HPTPPNEKSKRHRNKFNQVPLAVNNLNGSNVPLQSHSPL 422
+ K+ H G PP +++++ VNN+ ++V Q +
Sbjct: 310 SAAKQHVVQRRHTQGTNNRRQSTIPPYARTRQNLLSSPSKQTPVNNVVDASVATQKDG-I 368
Query: 423 PG 424
PG
Sbjct: 369 PG 370
>HsM5579454 [T] KOG1165 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 415
Score = 354 bits (909), Expect = 2e-97
Identities = 188/365 (51%), Positives = 239/365 (64%), Gaps = 21/365 (5%)
Query: 72 IVGLHYKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPRKTDAPQLKDEYRTYKILSGSE 131
+VG ++++GKKIG G+FG L G N+ N VAIK EP K+ APQL EYR YK LS +E
Sbjct: 41 MVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLSATE 100
Query: 132 GIPQAYYFGQEGLHNILVIDLLGPSLEDLFDWCGRRFSIKTVVHVAIQMITLIEELHDHD 191
G+PQ YYFG G +N +V++LLGPSLEDLFD C R F++KTV+ +AIQ+IT +E +H
Sbjct: 101 GVPQVYYFGPCGKYNAMVLELLGPSLEDLFDLCDRTFTLKTVLMIAIQLITRMEYVHTKS 160
Query: 192 LIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTARYMS 251
LIYRD+KP+NFL+GRP + +H+IDFG+AK Y DP+TK+HIPYRE KSL+GTARYMS
Sbjct: 161 LIYRDVKPENFLVGRPGTKRQHAIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMS 220
Query: 252 INTHLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKAANNKLKYEKIGEKKRSTNVYDLS 311
INTHLG+EQSRRDD+EALGH+F YFLRG LPWQGLKA K +Y+KIG+ KR+T + L
Sbjct: 221 INTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLC 280
Query: 312 QGLPVQFGRYLEIVRNLGFEETPDYEGYRKLLLSVLDELGQKLDGEYDWMKLNGGRGWDL 371
+ P + YL VR L F E PDY+ RKL + D G D EYDW
Sbjct: 281 ENFPEEMATYLRYVRRLDFFEKPDYDYLRKLFTDLFDRSGFVFDYEYDW----------- 329
Query: 372 AINKKPNLHGYGHPTPPNEKSKRHRNKFNQVPLAVNNLNGSNVPLQSHSPLPGGTDLTQG 431
A P G H P++ R + + + A+N+ NG L + P T G
Sbjct: 330 AGKPLPTPIGTVHTDLPSQPQLRDKTQPHSKNQALNSTNGE---LNADDP-------TAG 379
Query: 432 VSNAP 436
SNAP
Sbjct: 380 HSNAP 384
>Hs21314778 [T] KOG1165 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 415
Score = 354 bits (908), Expect = 2e-97
Identities = 188/365 (51%), Positives = 239/365 (64%), Gaps = 21/365 (5%)
Query: 72 IVGLHYKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPRKTDAPQLKDEYRTYKILSGSE 131
+VG ++++GKKIG G+FG L G N+ N VAIK EP K+ APQL EYR YK LS +E
Sbjct: 41 MVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLSATE 100
Query: 132 GIPQAYYFGQEGLHNILVIDLLGPSLEDLFDWCGRRFSIKTVVHVAIQMITLIEELHDHD 191
G+PQ YYFG G +N +V++LLGPSLEDLFD C R F++KTV+ +AIQ+IT +E +H
Sbjct: 101 GVPQVYYFGPCGNYNAMVLELLGPSLEDLFDLCDRTFTLKTVLMIAIQLITRMEYVHTKS 160
Query: 192 LIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTARYMS 251
LIYRD+KP+NFL+GRP + +H+IDFG+AK Y DP+TK+HIPYRE KSL+GTARYMS
Sbjct: 161 LIYRDVKPENFLVGRPGTKRQHAIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMS 220
Query: 252 INTHLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKAANNKLKYEKIGEKKRSTNVYDLS 311
INTHLG+EQSRRDD+EALGH+F YFLRG LPWQGLKA K +Y+KIG+ KR+T + L
Sbjct: 221 INTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLC 280
Query: 312 QGLPVQFGRYLEIVRNLGFEETPDYEGYRKLLLSVLDELGQKLDGEYDWMKLNGGRGWDL 371
+ P + YL VR L F E PDY+ RKL + D G D EYDW
Sbjct: 281 ENFPEEMATYLRYVRRLDFFEKPDYDYLRKLFTDLFDRSGFVFDYEYDW----------- 329
Query: 372 AINKKPNLHGYGHPTPPNEKSKRHRNKFNQVPLAVNNLNGSNVPLQSHSPLPGGTDLTQG 431
A P G H P++ R + + + A+N+ NG L + P T G
Sbjct: 330 AGKPLPTPIGTVHTDLPSQPQLRDKTQPHSKNQALNSTNGE---LNADDP-------TAG 379
Query: 432 VSNAP 436
SNAP
Sbjct: 380 HSNAP 384
>Hs4758080 [T] KOG1165 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 447
Score = 349 bits (895), Expect = 7e-96
Identities = 181/332 (54%), Positives = 230/332 (68%), Gaps = 13/332 (3%)
Query: 72 IVGLHYKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPRKTDAPQLKDEYRTYKILSGSE 131
+VG ++++GKKIG G+FG L G N+ N VAIK EP K+ APQL EYR YK L +
Sbjct: 38 MVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPMKSRAPQLHLEYRFYKQLGSGD 97
Query: 132 GIPQAYYFGQEGLHNILVIDLLGPSLEDLFDWCGRRFSIKTVVHVAIQMITLIEELHDHD 191
GIPQ YYFG G +N +V++LLGPSLEDLFD C R FS+KTV+ +AIQ+I+ +E +H +
Sbjct: 98 GIPQVYYFGPCGKYNAMVLELLGPSLEDLFDLCDRTFSLKTVLMIAIQLISRMEYVHSKN 157
Query: 192 LIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTARYMS 251
LIYRD+KP+NFLIGRP ++H+IDFG+AK Y DP+TK+HIPYRE KSL+GTARYMS
Sbjct: 158 LIYRDVKPENFLIGRPRNKTQQVIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMS 217
Query: 252 INTHLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKAANNKLKYEKIGEKKRSTNVYDLS 311
INTHLG+EQSRRDD+EALGH+F YFLRG LPWQGLKA K +Y+KIG+ KR+T + L
Sbjct: 218 INTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLC 277
Query: 312 QGLPVQFGRYLEIVRNLGFEETPDYEGYRKLLLSVLDELGQKLDGEYDWM--KLNGGRGW 369
+ P + YL VR L F E PDYE RKL + D G D EYDW+ +L G
Sbjct: 278 ENFP-EMATYLRYVRRLDFFEKPDYEYLRKLFTDLFDRKGYMFDYEYDWIGKQLPTPVG- 335
Query: 370 DLAINKKPNLHGYGHPTPPNEKSKRHRNKFNQ 401
A+ + P L N ++ +HR+K Q
Sbjct: 336 --AVQQDPALSS-------NREAHQHRDKMQQ 358
>7300125 [T] KOG1165 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 422
Score = 344 bits (883), Expect = 2e-94
Identities = 170/290 (58%), Positives = 216/290 (73%), Gaps = 1/290 (0%)
Query: 72 IVGLHYKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPRKTDAPQLKDEYRTYKIL-SGS 130
+VG ++++GKKIG G+FG L G N+ NN VAIK EP K+ APQL EYR YK+L S +
Sbjct: 16 MVGPNFRVGKKIGCGNFGELRLGKNLYNNEHVAIKMEPMKSKAPQLHLEYRFYKLLGSHA 75
Query: 131 EGIPQAYYFGQEGLHNILVIDLLGPSLEDLFDWCGRRFSIKTVVHVAIQMITLIEELHDH 190
EG+P+ YYFG G +N LV++LLGPSLEDLFD CGRRF++K+V+ +AIQ++ IE +H
Sbjct: 76 EGVPEVYYFGPCGKYNALVMELLGPSLEDLFDICGRRFTLKSVLLIAIQLLHRIEYVHSR 135
Query: 191 DLIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTARYM 250
LIYRD+KP+NFLIGR + ++H+IDFG+AK Y D T +HIPYRE KSL+GTARYM
Sbjct: 136 HLIYRDVKPENFLIGRTSTKREKIIHIIDFGLAKEYIDLDTNRHIPYREHKSLTGTARYM 195
Query: 251 SINTHLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKAANNKLKYEKIGEKKRSTNVYDL 310
SINTH+GREQSRRDD+EALGH+F YFLRG LPWQGLKA K +Y+KIG+ KR+T + L
Sbjct: 196 SINTHMGREQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVL 255
Query: 311 SQGLPVQFGRYLEIVRNLGFEETPDYEGYRKLLLSVLDELGQKLDGEYDW 360
G P +F YL VR L F ETPDY+ R+L + D G +GE+DW
Sbjct: 256 CDGHPEEFATYLRYVRRLDFFETPDYDFLRRLFQDLFDRKGYTDEGEFDW 305
>CE29604 [T] KOG1165 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 407
Score = 340 bits (872), Expect = 3e-93
Identities = 175/294 (59%), Positives = 214/294 (72%), Gaps = 1/294 (0%)
Query: 72 IVGLHYKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPRKTDAPQLKDEYRTYKILSGSE 131
+VG ++K+GKKIG G+FG L G N+ NN VAIK EP K+ APQL EYR YK+L +E
Sbjct: 23 MVGPNFKVGKKIGCGNFGELRLGKNLYNNEHVAIKLEPMKSKAPQLHLEYRFYKLLGQAE 82
Query: 132 GIPQAYYFGQEGLHNILVIDLLGPSLEDLFDWCGRRFSIKTVVHVAIQMITLIEELHDHD 191
G+PQ +YFG G +N LV++LLG SLEDLFD C R FS+KTV VA+Q+I IE +H
Sbjct: 83 GLPQVHYFGPCGKYNALVMELLGHSLEDLFDLCDRHFSLKTVAMVAMQLIRRIEYVHTKH 142
Query: 192 LIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTARYMS 251
LIYRD+KP+NFLIGR + +++H+IDFG+AK Y D T +HI YRE KSL+GTARYMS
Sbjct: 143 LIYRDVKPENFLIGRYSTRKQHVLHIIDFGLAKEYIDCDTGKHIAYREHKSLTGTARYMS 202
Query: 252 INTHLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKAANNKLKYEKIGEKKRSTNVYDLS 311
INTHLG+EQSRRDD+EALGH+F YFLRG LPWQGLKA K +Y+KIG+ KR T V L
Sbjct: 203 INTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRQTAVEVLC 262
Query: 312 QGLPVQFGRYLEIVRNLGFEETPDYEGYRKLLLSVLDELGQKLDGEYDWM-KLN 364
+G P +F +YL R L F ETPDY+ L SVLD LG D E+DW KLN
Sbjct: 263 EGFPDEFAQYLRYARRLDFFETPDYDFCYNLFKSVLDRLGATYDYEFDWTPKLN 316
>Hs11545751 [T] KOG1165 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 393
Score = 338 bits (866), Expect = 2e-92
Identities = 166/291 (57%), Positives = 213/291 (73%), Gaps = 1/291 (0%)
Query: 72 IVGLHYKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPRKTDAPQLKDEYRTYKIL-SGS 130
+VG ++++GKKIG G+FG L G N+ N VAIK EP K+ APQL EYR YK L S
Sbjct: 39 MVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLGSAG 98
Query: 131 EGIPQAYYFGQEGLHNILVIDLLGPSLEDLFDWCGRRFSIKTVVHVAIQMITLIEELHDH 190
EG+PQ YYFG G +N +V++LLGPSLEDLFD C R F++KTV+ +AIQ+++ +E +H
Sbjct: 99 EGLPQVYYFGPCGKYNAMVLELLGPSLEDLFDLCDRTFTLKTVLMIAIQLLSRMEYVHSK 158
Query: 191 DLIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTARYM 250
+LIYRD+KP+NFLIGR +++H+IDFG+AK Y DP+TK+HIPYRE KSL+GTARYM
Sbjct: 159 NLIYRDVKPENFLIGRQGNKKEHVIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYM 218
Query: 251 SINTHLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKAANNKLKYEKIGEKKRSTNVYDL 310
SINTHLG+EQSRRDD+EALGH+F YFLRG LPWQGLKA K +Y+KIG+ KR+T + L
Sbjct: 219 SINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRNTPIEAL 278
Query: 311 SQGLPVQFGRYLEIVRNLGFEETPDYEGYRKLLLSVLDELGQKLDGEYDWM 361
+ P + YL VR L F E PDYE R L + ++ G D YDW+
Sbjct: 279 CENFPEEMATYLRYVRRLDFFEKPDYEYLRTLFTDLFEKKGYTFDYAYDWV 329
>Hs19923746 [T] KOG1163 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 337
Score = 312 bits (800), Expect = 7e-85
Identities = 162/292 (55%), Positives = 201/292 (68%), Gaps = 2/292 (0%)
Query: 72 IVGLHYKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPRKTDAPQLKDEYRTYKILSGSE 131
IVG YK+ +KIG GSFG ++ +N+ N VA+K E +K PQL E + YKIL G
Sbjct: 12 IVGGKYKLVRKIGSGSFGDIYLAINITNGEEVAVKLESQKARHPQLLYESKLYKILQGGV 71
Query: 132 GIPQAYYFGQEGLHNILVIDLLGPSLEDLFDWCGRRFSIKTVVHVAIQMITLIEELHDHD 191
GIP ++GQE +N+LV+DLLGPSLEDLF++C RRF++KTV+ +A QMI+ IE +H +
Sbjct: 72 GIPHIRWYGQEKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMISRIEYVHTKN 131
Query: 192 LIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTARYMS 251
I+RDIKPDNFL+G N + LIDFG+AK YRD +T+QHIPYRE K+L+GTARY S
Sbjct: 132 FIHRDIKPDNFLMGIGRH--CNKLFLIDFGLAKKYRDNRTRQHIPYREDKNLTGTARYAS 189
Query: 252 INTHLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKAANNKLKYEKIGEKKRSTNVYDLS 311
IN HLG EQSRRDDME+LG+V YF R LPWQGLKAA K KYEKI EKK ST V L
Sbjct: 190 INAHLGIEQSRRDDMESLGYVLMYFNRTSLPWQGLKAATKKKKYEKISEKKMSTPVEVLC 249
Query: 312 QGLPVQFGRYLEIVRNLGFEETPDYEGYRKLLLSVLDELGQKLDGEYDWMKL 363
+G P +F YL R L FEE PDY R+L + L + D +DW L
Sbjct: 250 KGFPAEFAMYLNYCRGLRFEEAPDYMYLRQLFRILFRTLNHQYDYTFDWTML 301
>At3g23340 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 442
Score = 309 bits (791), Expect = 8e-84
Identities = 164/353 (46%), Positives = 219/353 (61%), Gaps = 5/353 (1%)
Query: 72 IVGLHYKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPRKTDAPQLKDEYRTYKILSGSE 131
++G +K+G+KIG GSFG L+ G+N+ VA+K EP KT PQL E + Y +L G
Sbjct: 4 VIGGKFKLGRKIGSGSFGELYIGINVQTGEEVALKLEPVKTKHPQLHYESKVYMLLQGGT 63
Query: 132 GIPQAYYFGQEGLHNILVIDLLGPSLEDLFDWCGRRFSIKTVVHVAIQMITLIEELHDHD 191
G+P +FG EG +N + IDLLGPSLEDLF++C R FS+KTV+ +A Q+I +E +H
Sbjct: 64 GVPHIKWFGVEGNYNCMAIDLLGPSLEDLFNYCTRSFSLKTVLMLADQLINRVEYMHSRG 123
Query: 192 LIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTARYMS 251
++RDIKPDNFL+G + AN V++ID+G+AK YRD +T +HIPYRE K+L+GTARY S
Sbjct: 124 FLHRDIKPDNFLMGLGRK--ANQVYIIDYGLAKKYRDLQTHKHIPYRENKNLTGTARYAS 181
Query: 252 INTHLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKAANNKLKYEKIGEKKRSTNVYDLS 311
+NTHLG EQSRRDD+E+LG+V YF+RG LPWQGLKA K KYEKI EKK T V L
Sbjct: 182 VNTHLGIEQSRRDDLESLGYVLMYFIRGSLPWQGLKAGTKKQKYEKISEKKMLTPVEVLC 241
Query: 312 QGLPVQFGRYLEIVRNLGFEETPDYEGYRKLLLSVLDELGQKLDGEYDWMKLNGGRGWDL 371
+ P +F Y R+L FE+ PDY ++L + G + D +DW L + +
Sbjct: 242 KSYPSEFTSYFHYCRSLRFEDKPDYSYLKRLFRDLFIREGYQFDYVFDWTILKYPQSGSI 301
Query: 372 A---INKKPNLHGYGHPTPPNEKSKRHRNKFNQVPLAVNNLNGSNVPLQSHSP 421
+ N KP L G NEK ++ + AV NVP P
Sbjct: 302 SKPRPNPKPALDPPGPSAERNEKPIVGQDLRERFSGAVEAFARRNVPSHGIRP 354
>Hs4503093 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 416
Score = 308 bits (789), Expect = 1e-83
Identities = 154/294 (52%), Positives = 205/294 (69%), Gaps = 2/294 (0%)
Query: 73 VGLHYKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPRKTDAPQLKDEYRTYKILSGSEG 132
VG Y++G+KIG GSFG ++ G N+ + VAIK E KT PQL E + YK++ G G
Sbjct: 5 VGNKYRLGRKIGSGSFGDIYLGANIASGEEVAIKLECVKTKHPQLHIESKFYKMMQGGVG 64
Query: 133 IPQAYYFGQEGLHNILVIDLLGPSLEDLFDWCGRRFSIKTVVHVAIQMITLIEELHDHDL 192
IP + G EG +N++V++LLGPSLEDLF++C R+FS+KTV+ +A QMI+ IE +H +
Sbjct: 65 IPSIKWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNF 124
Query: 193 IYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTARYMSI 252
I+RD+KPDNFL+G + N+V++IDFG+AK YRD +T QHIPYRE K+L+GTARY SI
Sbjct: 125 IHRDVKPDNFLMGLGKK--GNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASI 182
Query: 253 NTHLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKAANNKLKYEKIGEKKRSTNVYDLSQ 312
NTHLG EQSRRDD+E+LG+V YF G LPWQGLKAA + KYE+I EKK ST + L +
Sbjct: 183 NTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVLCK 242
Query: 313 GLPVQFGRYLEIVRNLGFEETPDYEGYRKLLLSVLDELGQKLDGEYDWMKLNGG 366
G P +F YL R+L F++ PDY R+L ++ G D +DW L G
Sbjct: 243 GYPSEFSTYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKFG 296
>Hs21624639 [T] KOG1163 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 337
Score = 308 bits (789), Expect = 1e-83
Identities = 164/329 (49%), Positives = 207/329 (62%), Gaps = 7/329 (2%)
Query: 72 IVGLHYKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPRKTDAPQLKDEYRTYKILSGSE 131
+VG YK+ +KIG GSFG ++ G+ N VA+K E +K PQL E + Y IL G
Sbjct: 12 VVGGKYKLVRKIGSGSFGDVYLGITTTNGEEVAVKLESQKVKHPQLLYESKLYTILQGGV 71
Query: 132 GIPQAYYFGQEGLHNILVIDLLGPSLEDLFDWCGRRFSIKTVVHVAIQMITLIEELHDHD 191
GIP +++GQE +N+LV+DLLGPSLEDLF++C RRF++KTV+ +A QMI+ IE +H +
Sbjct: 72 GIPHMHWYGQEKDNNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMISRIEYVHTKN 131
Query: 192 LIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTARYMS 251
++RDIKPDNFL+G N + LIDFG+AK YRD +T+QHIPYRE K L GT RY S
Sbjct: 132 FLHRDIKPDNFLMGTGRH--CNKLFLIDFGLAKKYRDNRTRQHIPYREDKHLIGTVRYAS 189
Query: 252 INTHLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKAANNKLKYEKIGEKKRSTNVYDLS 311
IN HLG EQSRRDDME+LG+VF YF R LPWQGLKA K KYEKI EKK ST V L
Sbjct: 190 INAHLGIEQSRRDDMESLGYVFMYFNRTSLPWQGLKAMTKKQKYEKISEKKMSTPVEVLC 249
Query: 312 QGLPVQFGRYLEIVRNLGFEETPDYEGYRKLLLSVLDELGQKLDGEYDWMKLNGGRGWDL 371
+G P +F YL R L FEE PDY R+L + L + D +DW L
Sbjct: 250 KGFPAEFAMYLNYCRGLRFEEVPDYMYLRQLFRILFRTLNHQYDYTFDWTMLK-----QK 304
Query: 372 AINKKPNLHGYGHPTPPNEKSKRHRNKFN 400
A + + G G + +NK N
Sbjct: 305 AAQQAASSSGQGQQAQTQTGKQTEKNKNN 333
>At5g43320 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 480
Score = 308 bits (789), Expect = 1e-83
Identities = 152/289 (52%), Positives = 201/289 (68%), Gaps = 2/289 (0%)
Query: 72 IVGLHYKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPRKTDAPQLKDEYRTYKILSGSE 131
+VG YK+G+K+G GSFG LF GVN+ VA+K EP + PQL E + Y +L G
Sbjct: 4 VVGGKYKLGRKLGSGSFGELFLGVNVQTGEEVAVKLEPARARHPQLHYESKLYMLLQGGT 63
Query: 132 GIPQAYYFGQEGLHNILVIDLLGPSLEDLFDWCGRRFSIKTVVHVAIQMITLIEELHDHD 191
GIP ++G EG +N +VIDLLGPS+EDLF++C RRF++KTV+ +A QMI +E +H
Sbjct: 64 GIPHLKWYGVEGEYNCMVIDLLGPSMEDLFNYCSRRFNLKTVLMLADQMINRVEYMHVRG 123
Query: 192 LIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTARYMS 251
++RDIKPDNFL+G + AN V++ID+G+AK YRD +T +HIPYRE K+L+GTARY S
Sbjct: 124 FLHRDIKPDNFLMGLGRK--ANQVYIIDYGLAKKYRDLQTHRHIPYRENKNLTGTARYAS 181
Query: 252 INTHLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKAANNKLKYEKIGEKKRSTNVYDLS 311
+NTHLG EQSRRDD+E+LG+V YFLRG LPWQGL+A K KY+KI EKKR T V L
Sbjct: 182 VNTHLGIEQSRRDDLESLGYVLMYFLRGSLPWQGLRAGTKKQKYDKISEKKRLTPVEVLC 241
Query: 312 QGLPVQFGRYLEIVRNLGFEETPDYEGYRKLLLSVLDELGQKLDGEYDW 360
+ P +F Y VR+L FE+ PDY ++L + G + D +DW
Sbjct: 242 KSFPPEFTSYFLYVRSLRFEDKPDYPYLKRLFRDLFIREGYQFDYVFDW 290
>SPBC3H7.15 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 365
Score = 308 bits (788), Expect = 2e-83
Identities = 156/288 (54%), Positives = 200/288 (69%), Gaps = 2/288 (0%)
Query: 73 VGLHYKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPRKTDAPQLKDEYRTYKILSGSEG 132
+G Y+IG+KIG GSFG ++ G N+++ VAIK E + PQL+ EYR Y+ILSG G
Sbjct: 7 IGNKYRIGRKIGSGSFGDIYLGTNVVSGEEVAIKLESTRAKHPQLEYEYRVYRILSGGVG 66
Query: 133 IPQAYYFGQEGLHNILVIDLLGPSLEDLFDWCGRRFSIKTVVHVAIQMITLIEELHDHDL 192
IP +FG E +N +V+DLLGPSLEDLF++C R+FS+KTV+ +A Q+I+ IE +H
Sbjct: 67 IPFVRWFGVECDYNAMVMDLLGPSLEDLFNFCNRKFSLKTVLLLADQLISRIEFIHSKSF 126
Query: 193 IYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTARYMSI 252
++RDIKPDNFL+G + N V++IDFG+AK YRD KT HIPYRE K+L+GTARY SI
Sbjct: 127 LHRDIKPDNFLMGIGKR--GNQVNIIDFGLAKKYRDHKTHLHIPYRENKNLTGTARYASI 184
Query: 253 NTHLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKAANNKLKYEKIGEKKRSTNVYDLSQ 312
NTHLG EQSRRDD+E+LG+V YF RG LPWQGLKA K KYEKI EKK ST L +
Sbjct: 185 NTHLGIEQSRRDDLESLGYVLVYFCRGSLPWQGLKATTKKQKYEKIMEKKISTPTEVLCR 244
Query: 313 GLPVQFGRYLEIVRNLGFEETPDYEGYRKLLLSVLDELGQKLDGEYDW 360
G P +F YL R+L F++ PDY RKL + + D +DW
Sbjct: 245 GFPQEFSIYLNYTRSLRFDDKPDYAYLRKLFRDLFCRQSYEFDYMFDW 292
>Hs17475657 [T] KOG1163 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 337
Score = 307 bits (786), Expect = 3e-83
Identities = 163/329 (49%), Positives = 207/329 (62%), Gaps = 7/329 (2%)
Query: 72 IVGLHYKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPRKTDAPQLKDEYRTYKILSGSE 131
+VG YK+ +KIG GSFG ++ G+ N VA+K E +K PQL E + Y IL G
Sbjct: 12 VVGGKYKLVRKIGSGSFGDVYLGITTTNGEDVAVKLESQKVKHPQLLYESKLYTILQGGV 71
Query: 132 GIPQAYYFGQEGLHNILVIDLLGPSLEDLFDWCGRRFSIKTVVHVAIQMITLIEELHDHD 191
GIP +++GQE +N+LV+DLLGPSLEDLF++C RRF++KTV+ +A QMI+ IE +H +
Sbjct: 72 GIPHMHWYGQEKDNNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMISRIEYVHTKN 131
Query: 192 LIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTARYMS 251
++RDIKPDNFL+G N + LIDFG+AK YRD +T+QHIPYRE K L GT RY S
Sbjct: 132 FLHRDIKPDNFLMGTGRH--CNKLFLIDFGLAKKYRDNRTRQHIPYREDKHLIGTVRYAS 189
Query: 252 INTHLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKAANNKLKYEKIGEKKRSTNVYDLS 311
IN HLG EQSRRDDME+LG+VF YF R LPWQGL+A K KYEKI EKK ST V L
Sbjct: 190 INAHLGIEQSRRDDMESLGYVFMYFNRTSLPWQGLRAMTKKQKYEKISEKKMSTPVEVLC 249
Query: 312 QGLPVQFGRYLEIVRNLGFEETPDYEGYRKLLLSVLDELGQKLDGEYDWMKLNGGRGWDL 371
+G P +F YL R L FEE PDY R+L + L + D +DW L
Sbjct: 250 KGFPAEFAMYLNYCRGLRFEEVPDYMYLRQLFRILFRTLNHQYDYTFDWTMLK-----QK 304
Query: 372 AINKKPNLHGYGHPTPPNEKSKRHRNKFN 400
A + + G G + +NK N
Sbjct: 305 AAQQAASSSGQGQQAQTQTGKQTEKNKNN 333
>At2g19470 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 433
Score = 306 bits (785), Expect = 4e-83
Identities = 164/364 (45%), Positives = 227/364 (62%), Gaps = 10/364 (2%)
Query: 73 VGLHYKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPRKTDAPQLKDEYRTYKILSGSEG 132
VG +++G+KIG GSFG ++ G ++ N VAIK E KT PQL E R Y++L G G
Sbjct: 5 VGNKFRLGRKIGSGSFGEIYLGTDVQTNEEVAIKLESVKTAHPQLSYESRIYRVLQGGTG 64
Query: 133 IPQAYYFGQEGLHNILVIDLLGPSLEDLFDWCGRRFSIKTVVHVAIQMITLIEELHDHDL 192
IP ++G EG +N+LV+DLLGPSLEDLF +C R+FS+KTV+ +A QMI +E +H
Sbjct: 65 IPNMKWYGVEGDYNVLVMDLLGPSLEDLFSYCKRQFSLKTVLMLADQMINRLEFIHSKSY 124
Query: 193 IYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTARYMSI 252
++RDIKPDNFL+G + AN V++ID+G+AK YRD T +HIPYRE KSL GT RY S+
Sbjct: 125 LHRDIKPDNFLMGLGRR--ANQVYIIDYGLAKKYRDSSTHRHIPYRENKSLIGTPRYASL 182
Query: 253 NTHLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKAANNKLKYEKIGEKKRSTNVYDLSQ 312
NTHLG EQSRRDD+E+LG++ YFL+G LPWQGLKA N K KY+KI EKK ST++ L +
Sbjct: 183 NTHLGIEQSRRDDIESLGYILMYFLKGSLPWQGLKAGNKKQKYDKISEKKVSTSIETLCR 242
Query: 313 GLPVQFGRYLEIVRNLGFEETPDYEGYRKLLLSVLDELGQKLDGEYDWMKLNGGRGWDLA 372
G P +F Y R+L F++ PDY ++L ++ G + D +DW +
Sbjct: 243 GHPTEFASYFHYCRSLRFDDKPDYAYLKRLFRNLFIREGFQFDFVFDWTVYKYQQSQSGN 302
Query: 373 INKKPNLHGYGHPT---PPNEKSKRHRNKFNQ-----VPLAVNNLNGSNVPLQSHSPLPG 424
+P+ G G + P S++ + NQ L + NG++ + LPG
Sbjct: 303 PQPRPHDGGVGTSSGLNPAVGNSEKRPDVPNQRTNPDFTLKQKDKNGNDSAIAKDKLLPG 362
Query: 425 GTDL 428
+L
Sbjct: 363 SLNL 366
>YPL204w [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 494
Score = 306 bits (783), Expect = 7e-83
Identities = 161/337 (47%), Positives = 218/337 (63%), Gaps = 8/337 (2%)
Query: 73 VGLHYKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPRKTDAPQLKDEYRTYKILSGSEG 132
VG ++IG+KIG GSFG ++ G N+I+ VAIK E ++ PQL E R Y+ LSG G
Sbjct: 5 VGRKFRIGRKIGSGSFGDIYHGTNLISGEEVAIKLESIRSRHPQLDYESRVYRYLSGGVG 64
Query: 133 IPQAYYFGQEGLHNILVIDLLGPSLEDLFDWCGRRFSIKTVVHVAIQMITLIEELHDHDL 192
IP +FG+EG +N +VIDLLGPSLEDLF++C RRFS KTV+ +A+QM I+ +H
Sbjct: 65 IPFIRWFGREGEYNAMVIDLLGPSLEDLFNYCHRRFSFKTVIMLALQMFCRIQYIHGRSF 124
Query: 193 IYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTARYMSI 252
I+RDIKPDNFL+G + + VH+IDFG++K YRD T +HIPYRE KSL+GTARY S+
Sbjct: 125 IHRDIKPDNFLMGVGRR--GSTVHVIDFGLSKKYRDFNTHRHIPYRENKSLTGTARYASV 182
Query: 253 NTHLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKAANNKLKYEKIGEKKRSTNVYDLSQ 312
NTHLG EQSRRDD+E+LG+V YF +G LPWQGLKA K KY++I EKK + +V L
Sbjct: 183 NTHLGIEQSRRDDLESLGYVLIYFCKGSLPWQGLKATTKKQKYDRIMEKKLNVSVETLCS 242
Query: 313 GLPVQFGRYLEIVRNLGFEETPDYEGYRKLLLSVLDELGQKLDGEYDWMKLNGGRGW--- 369
GLP++F Y+ +NL F+E PDY +L + +L D +DW L +
Sbjct: 243 GLPLEFQEYMAYCKNLKFDEKPDYLFLARLFKDLSIKLEYHNDHLFDWTMLRYTKAMVEK 302
Query: 370 --DLAINKKPNLHGYGHPTPPNEKSKRHRNKFNQVPL 404
DL I +K +L+ + + + FN++ L
Sbjct: 303 QRDLLI-EKGDLNANSNAASASNSTDNKSETFNKIKL 338
>CE00872 [T] KOG1163 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 341
Score = 306 bits (783), Expect = 7e-83
Identities = 157/292 (53%), Positives = 199/292 (67%), Gaps = 2/292 (0%)
Query: 72 IVGLHYKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPRKTDAPQLKDEYRTYKILSGSE 131
IV YK+ +KIG GSFG ++ +N+ N VAIK E + PQL E + Y+IL G
Sbjct: 11 IVATKYKLIRKIGSGSFGDIYVSINVTNGEEVAIKLESNRARHPQLLYESKVYRILQGGV 70
Query: 132 GIPQAYYFGQEGLHNILVIDLLGPSLEDLFDWCGRRFSIKTVVHVAIQMITLIEELHDHD 191
GIP ++G E +N+LV+DLLGPSLEDLF++C RRF++KTV+ +A QMI IE +H +
Sbjct: 71 GIPHIRWYGTEREYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMIGRIEYVHVKN 130
Query: 192 LIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTARYMS 251
I+RDIKPDNFL+G N + LIDFG+AK YRD +T+ HIPYRE K+L+GTARY S
Sbjct: 131 FIHRDIKPDNFLMGIGRH--CNKLFLIDFGLAKKYRDSRTRTHIPYREDKNLTGTARYAS 188
Query: 252 INTHLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKAANNKLKYEKIGEKKRSTNVYDLS 311
IN HLG EQSRRDDME+LG+V YF RG LPWQGLKAA K KYEKI EKK +T+V L
Sbjct: 189 INAHLGIEQSRRDDMESLGYVLMYFNRGTLPWQGLKAATKKQKYEKISEKKMTTSVEHLC 248
Query: 312 QGLPVQFGRYLEIVRNLGFEETPDYEGYRKLLLSVLDELGQKLDGEYDWMKL 363
+G P +F YL R L F+E+PDY R+L + L + D +DW L
Sbjct: 249 KGFPAEFPMYLSYTRGLRFDESPDYMYLRQLFRILFRTLNHQYDYTFDWTML 300
>At4g14340 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 457
Score = 306 bits (783), Expect = 7e-83
Identities = 153/316 (48%), Positives = 209/316 (65%), Gaps = 13/316 (4%)
Query: 72 IVGLHYKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPRKTDAPQLKDEYRTYKILSGSE 131
++G +K+G+K+G GSFG L+ G+N+ VA+K EP KT PQL+ E + Y L G
Sbjct: 10 VIGGKFKLGRKLGSGSFGELYLGINIQTGEEVAVKLEPVKTRHPQLQYESKIYMFLQGGT 69
Query: 132 GIPQAYYFGQEGLHNILVIDLLGPSLEDLFDWCGRRFSIKTVVHVAIQMITLIEELHDHD 191
G+P +FG EG ++ +VIDLLGPSLEDLF++C R FS+K+V+ +A Q+I +E +H
Sbjct: 70 GVPHLKWFGVEGEYSCMVIDLLGPSLEDLFNYCKRIFSLKSVLMLADQLICRVEYMHSRG 129
Query: 192 LIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTARYMS 251
++RDIKPDNFL+G + AN V++ID+G+AK Y+D +T++HIPYRE K+L+GTARY S
Sbjct: 130 FLHRDIKPDNFLMGLGRR--ANQVYIIDYGLAKKYKDLQTQKHIPYRENKNLTGTARYAS 187
Query: 252 INTHLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKAANNKLKYEKIGEKKRSTNVYDLS 311
+NTHLG EQSRRDD+E+LG+V YFLRG LPWQGLKA K KY+KI EKK T+V L
Sbjct: 188 VNTHLGIEQSRRDDLESLGYVLMYFLRGSLPWQGLKAGTKKQKYDKISEKKMLTSVETLC 247
Query: 312 QGLPVQFGRYLEIVRNLGFEETPDYEGYRKLLLSVLDELGQKLDGEYDWMKLNGGRGWDL 371
+ P +F Y R+L FE+ PDY R+L + G +LD +DW
Sbjct: 248 KSYPSEFTSYFHYCRSLRFEDKPDYSYLRRLFRDLFIREGYQLDYVFDW----------- 296
Query: 372 AINKKPNLHGYGHPTP 387
I+K P + P P
Sbjct: 297 TISKYPQIGSSSRPRP 312
>At1g04440 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 468
Score = 306 bits (783), Expect = 7e-83
Identities = 164/357 (45%), Positives = 224/357 (61%), Gaps = 12/357 (3%)
Query: 72 IVGLHYKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPRKTDAPQLKDEYRTYKILSGSE 131
+VG +K+G+K+G GSFG +F GVN+ VA+K EP + PQL E + Y +L G
Sbjct: 4 VVGGKFKLGRKLGSGSFGEIFLGVNVQTGEEVAVKLEPLRARHPQLHYESKLYMLLQGGT 63
Query: 132 GIPQAYYFGQEGLHNILVIDLLGPSLEDLFDWCGRRFSIKTVVHVAIQMITLIEELHDHD 191
GIP +FG EG N +VIDLLGPS+E+ F++C R FS+KTV+ +A QMI +E +H
Sbjct: 64 GIPHLKWFGVEGEFNCMVIDLLGPSMEEFFNYCSRSFSLKTVLMLADQMINRVEYMHVKG 123
Query: 192 LIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTARYMS 251
++RDIKPDNFL+G + AN V++ID+G+AK YRD +T +HIPYRE K+L+GTARY S
Sbjct: 124 FLHRDIKPDNFLMGLGRK--ANQVYIIDYGLAKKYRDLQTHKHIPYRENKNLTGTARYAS 181
Query: 252 INTHLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKAANNKLKYEKIGEKKRSTNVYDLS 311
+NTHLG EQSRRDD+E+LG++ YFLRG LPWQGL+A K KY+KI EKKR T V L
Sbjct: 182 VNTHLGIEQSRRDDLESLGYLLMYFLRGSLPWQGLRAGTKKQKYDKISEKKRLTPVEVLC 241
Query: 312 QGLPVQFGRYLEIVRNLGFEETPDYEGYRKLLLSVLDELGQKLDGEYDWMKLNGGR-GWD 370
+ P +F Y VR+L FE+ PDY ++L + G + D +DW L + G
Sbjct: 242 KNFPPEFTSYFLYVRSLRFEDKPDYSYLKRLFRDLFIREGYQFDYVFDWTILRYPQFGSS 301
Query: 371 LAINKKPN---LHGYGHPTPPNEKSKR------HRNKFNQVPLAVNNLNGSNVPLQS 418
+ N KP P P +K+++ R +F+ V A NGS +Q+
Sbjct: 302 SSSNSKPRPTLRPAMNIPVPSADKAEKPPIGQDSRERFSGVFEAYTRRNGSGTGVQA 358
>Hs20544145 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 409
Score = 305 bits (782), Expect = 9e-83
Identities = 153/294 (52%), Positives = 204/294 (69%), Gaps = 2/294 (0%)
Query: 73 VGLHYKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPRKTDAPQLKDEYRTYKILSGSEG 132
VG Y++G+KIG GSFG ++ G ++ VAIK E KT PQL E + YK++ G G
Sbjct: 5 VGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQGGVG 64
Query: 133 IPQAYYFGQEGLHNILVIDLLGPSLEDLFDWCGRRFSIKTVVHVAIQMITLIEELHDHDL 192
IP + G EG +N++V++LLGPSLEDLF++C R+FS+KTV+ +A QMI+ IE +H +
Sbjct: 65 IPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNF 124
Query: 193 IYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTARYMSI 252
I+RD+KPDNFL+G + N+V++IDFG+AK YRD +T QHIPYRE K+L+GTARY SI
Sbjct: 125 IHRDVKPDNFLMGLGKK--GNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASI 182
Query: 253 NTHLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKAANNKLKYEKIGEKKRSTNVYDLSQ 312
NTHLG EQSRRDD+E+LG+V YF G LPWQGLKAA + KYE+I EKK ST + L +
Sbjct: 183 NTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVLCK 242
Query: 313 GLPVQFGRYLEIVRNLGFEETPDYEGYRKLLLSVLDELGQKLDGEYDWMKLNGG 366
G P +F YL R+L F++ PDY R+L ++ G D +DW L G
Sbjct: 243 GYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKFG 296
>Hs20149530 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 415
Score = 305 bits (782), Expect = 9e-83
Identities = 153/294 (52%), Positives = 204/294 (69%), Gaps = 2/294 (0%)
Query: 73 VGLHYKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPRKTDAPQLKDEYRTYKILSGSEG 132
VG Y++G+KIG GSFG ++ G ++ VAIK E KT PQL E + YK++ G G
Sbjct: 5 VGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQGGVG 64
Query: 133 IPQAYYFGQEGLHNILVIDLLGPSLEDLFDWCGRRFSIKTVVHVAIQMITLIEELHDHDL 192
IP + G EG +N++V++LLGPSLEDLF++C R+FS+KTV+ +A QMI+ IE +H +
Sbjct: 65 IPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNF 124
Query: 193 IYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTARYMSI 252
I+RD+KPDNFL+G + N+V++IDFG+AK YRD +T QHIPYRE K+L+GTARY SI
Sbjct: 125 IHRDVKPDNFLMGLGKK--GNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASI 182
Query: 253 NTHLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKAANNKLKYEKIGEKKRSTNVYDLSQ 312
NTHLG EQSRRDD+E+LG+V YF G LPWQGLKAA + KYE+I EKK ST + L +
Sbjct: 183 NTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVLCK 242
Query: 313 GLPVQFGRYLEIVRNLGFEETPDYEGYRKLLLSVLDELGQKLDGEYDWMKLNGG 366
G P +F YL R+L F++ PDY R+L ++ G D +DW L G
Sbjct: 243 GYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKFG 296
>At1g72710 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 465
Score = 305 bits (780), Expect = 1e-82
Identities = 154/288 (53%), Positives = 200/288 (68%), Gaps = 3/288 (1%)
Query: 73 VGLHYKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPRKTDAPQLKDEYRTYKILSGSEG 132
VG +++G+KIG GSFG ++ G N+ N VAIK E KT PQL E + YK+L G G
Sbjct: 5 VGNKFRLGRKIGGGSFGEIYLGTNIQTNEEVAIKLENVKTKHPQLLYESKLYKVLQGGTG 64
Query: 133 IPQAYYFGQEGLHNILVIDLLGPSLEDLFDWCGRRFSIKTVVHVAIQMITLIEELHDHDL 192
+P ++G EG +N+LVIDLLGPSLEDLF++C R+ S+KTV+ +A QMI IE +H
Sbjct: 65 VPNVKWYGVEGDYNVLVIDLLGPSLEDLFNFCSRKLSLKTVLMLADQMINRIEFVHQKSF 124
Query: 193 IYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTARYMSI 252
++RDIKPDNFL+G + AN V++IDFG+AK YRD QHIPYRE K+L+GTARY S+
Sbjct: 125 LHRDIKPDNFLMGLGRR--ANQVYVIDFGLAKKYRD-SNHQHIPYRENKNLTGTARYASM 181
Query: 253 NTHLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKAANNKLKYEKIGEKKRSTNVYDLSQ 312
NTHLG EQSRRDD+E+LG V YFL+G LPWQGLKA N K KYEKI EKK ST++ L +
Sbjct: 182 NTHLGIEQSRRDDLESLGFVLMYFLKGSLPWQGLKAGNKKQKYEKISEKKVSTSIEALCR 241
Query: 313 GLPVQFGRYLEIVRNLGFEETPDYEGYRKLLLSVLDELGQKLDGEYDW 360
G P +F Y R+L F++ PDY ++L + G + D +DW
Sbjct: 242 GYPSEFASYFHYCRSLRFDDKPDYAYLKRLFRDLFIREGFQFDYVFDW 289
>7302004 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 440
Score = 305 bits (780), Expect = 1e-82
Identities = 153/294 (52%), Positives = 205/294 (69%), Gaps = 2/294 (0%)
Query: 73 VGLHYKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPRKTDAPQLKDEYRTYKILSGSEG 132
VG Y++G+KIG GSFG ++ G + VAIK E +T PQL E + YK + G G
Sbjct: 5 VGNKYRLGRKIGSGSFGDIYLGTTINTGEEVAIKLECIRTKHPQLHIESKFYKTMQGGIG 64
Query: 133 IPQAYYFGQEGLHNILVIDLLGPSLEDLFDWCGRRFSIKTVVHVAIQMITLIEELHDHDL 192
IP+ + G EG +N++V++LLGPSLEDLF++C RRFS+KTV+ +A QMI+ I+ +H D
Sbjct: 65 IPRIIWCGSEGDYNVMVMELLGPSLEDLFNFCSRRFSLKTVLLLADQMISRIDYIHSRDF 124
Query: 193 IYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTARYMSI 252
I+RDIKPDNFL+G + N+V++IDFG+AK +RD ++ +HIPYRE K+L+GTARY SI
Sbjct: 125 IHRDIKPDNFLMGLGKK--GNLVYIIDFGLAKKFRDARSLKHIPYRENKNLTGTARYASI 182
Query: 253 NTHLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKAANNKLKYEKIGEKKRSTNVYDLSQ 312
NTHLG EQSRRDD+E+LG+V YF G LPWQGLKAAN + KYE+I EKK ST++ L +
Sbjct: 183 NTHLGIEQSRRDDLESLGYVLMYFNLGALPWQGLKAANKRQKYERISEKKLSTSIVVLCK 242
Query: 313 GLPVQFGRYLEIVRNLGFEETPDYEGYRKLLLSVLDELGQKLDGEYDWMKLNGG 366
G P +F YL R + F++ PDY RKL ++ LG D +DW L G
Sbjct: 243 GFPSEFVNYLNFCRQMHFDQRPDYCHLRKLFRNLFHRLGFTYDYVFDWNLLKFG 296
>At4g26100 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 450
Score = 303 bits (776), Expect = 4e-82
Identities = 147/288 (51%), Positives = 200/288 (69%), Gaps = 2/288 (0%)
Query: 73 VGLHYKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPRKTDAPQLKDEYRTYKILSGSEG 132
VG +++G+KIG GSFG ++ G N+ N +AIK E KT PQL E + Y+IL G G
Sbjct: 5 VGNKFRLGRKIGSGSFGEIYLGTNIHTNEELAIKLENVKTKHPQLLYESKLYRILQGGTG 64
Query: 133 IPQAYYFGQEGLHNILVIDLLGPSLEDLFDWCGRRFSIKTVVHVAIQMITLIEELHDHDL 192
+P +FG EG +N+LV+DLLGPSLEDLF++C R+ S+K+V+ +A QMI +E H
Sbjct: 65 VPNVKWFGVEGDYNVLVMDLLGPSLEDLFNFCSRKLSLKSVLMLADQMINRVEFFHSKSF 124
Query: 193 IYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTARYMSI 252
++RD+KPDNFL+G + AN V++IDFG+AK YRD T QHIPYRE K+L+GTARY S+
Sbjct: 125 LHRDLKPDNFLMGLGRR--ANQVYIIDFGLAKKYRDSTTHQHIPYRENKNLTGTARYASM 182
Query: 253 NTHLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKAANNKLKYEKIGEKKRSTNVYDLSQ 312
NTHLG EQSRRDD+E+LG++ YFL+G LPWQGLKA K KYE+I EKK ST++ L +
Sbjct: 183 NTHLGIEQSRRDDLESLGYILMYFLKGSLPWQGLKAGTKKQKYERISEKKVSTSIEALCR 242
Query: 313 GLPVQFGRYLEIVRNLGFEETPDYEGYRKLLLSVLDELGQKLDGEYDW 360
G P +F Y R+L F++ PDY +++ + G + D +DW
Sbjct: 243 GYPSEFASYFHYCRSLRFDDKPDYAYLKRIFRDLFIREGFQFDYVFDW 290
>At4g28540 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 321
Score = 301 bits (772), Expect = 1e-81
Identities = 148/292 (50%), Positives = 200/292 (67%), Gaps = 2/292 (0%)
Query: 72 IVGLHYKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPRKTDAPQLKDEYRTYKILSGSE 131
++G +K+G+KIG GSFG LF V++ A+K EP KT PQL E + Y +L G
Sbjct: 4 VIGGKFKLGRKIGGGSFGELFLAVSLQTGEEAAVKLEPAKTKHPQLHYESKIYMLLQGGS 63
Query: 132 GIPQAYYFGQEGLHNILVIDLLGPSLEDLFDWCGRRFSIKTVVHVAIQMITLIEELHDHD 191
GIP +FG +G +N +VIDLLGPSLEDLF++C RR ++K V+ +A Q+I+ +E +H
Sbjct: 64 GIPSLKWFGVQGDYNAMVIDLLGPSLEDLFNYCNRRLTLKAVLMLADQLISRVEYMHSRG 123
Query: 192 LIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTARYMS 251
++RDIKPDNFL+G + AN V++IDFG+AK YRD +T +HIPYRE K+L+GTARY S
Sbjct: 124 FLHRDIKPDNFLMGLGRK--ANQVYIIDFGLAKKYRDLQTHRHIPYRENKNLTGTARYAS 181
Query: 252 INTHLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKAANNKLKYEKIGEKKRSTNVYDLS 311
+NTHLG EQSRRDD+E+LG+V YFLRG LPWQGLKA K KY++I EKK ST + L
Sbjct: 182 VNTHLGVEQSRRDDLESLGYVLMYFLRGSLPWQGLKAGTKKQKYDRISEKKVSTPIEVLC 241
Query: 312 QGLPVQFGRYLEIVRNLGFEETPDYEGYRKLLLSVLDELGQKLDGEYDWMKL 363
+ P +F Y + R+L FE+ PDY ++L + G + D +DW L
Sbjct: 242 KSYPPEFVSYFQYCRSLRFEDKPDYSYLKRLFRDLFIREGYQFDYVFDWTAL 293
>CE05879 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 578
Score = 299 bits (766), Expect = 6e-81
Identities = 156/292 (53%), Positives = 202/292 (68%), Gaps = 3/292 (1%)
Query: 73 VGLHYKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPRKTDAPQLKDEYRTYKILSGSEG 132
VG +++G+KIG GSFG ++ G N+ N VA+K E K+ PQL E R Y+I+ G G
Sbjct: 184 VGNRFRLGRKIGSGSFGDIYLGQNIQTNEEVAVKLECVKSKHPQLHIESRLYRIMLGGIG 243
Query: 133 IPQAYYFGQEGLHNILVIDLLGPSLEDLFDWCGRRFSIKTVVHVAIQMITLIEELHDHDL 192
IP+ + GQEG +N++V++LLGPSLEDLF++C R+FS+KTV+ +A QM++ +E +H D
Sbjct: 244 IPEIRWCGQEGDYNVMVMELLGPSLEDLFNFCQRKFSLKTVLLLADQMLSRVEFIHCRDY 303
Query: 193 IYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTARYMSI 252
I+RDIKPDNFL+G + N+V++IDFG+AK YRD K QHI YRE K+L+GTARY SI
Sbjct: 304 IHRDIKPDNFLMGLGKR--GNLVYIIDFGLAKRYRDSK-HQHIAYRENKNLTGTARYASI 360
Query: 253 NTHLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKAANNKLKYEKIGEKKRSTNVYDLSQ 312
NTH G EQSRRDD+E+LG+VF YF RG LPWQGLKA + KYE I EKK ST V DL
Sbjct: 361 NTHRGIEQSRRDDIESLGYVFMYFNRGTLPWQGLKAVTKRQKYELISEKKISTRVDDLCA 420
Query: 313 GLPVQFGRYLEIVRNLGFEETPDYEGYRKLLLSVLDELGQKLDGEYDWMKLN 364
G P F +YL R+LGFEE PDY R L ++ D +DW N
Sbjct: 421 GYPEAFAQYLNYCRSLGFEEQPDYGYLRNLFRTLFHRQQFCYDYVFDWNTYN 472
>At1g03930 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 471
Score = 298 bits (764), Expect = 1e-80
Identities = 145/292 (49%), Positives = 200/292 (67%), Gaps = 2/292 (0%)
Query: 72 IVGLHYKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPRKTDAPQLKDEYRTYKILSGSE 131
++G +K+G+KIG GSFG L+ G+N+ VA+K E KT PQL E + Y +L G
Sbjct: 4 VIGGKFKLGRKIGSGSFGELYLGINVQTGEEVAVKLESVKTKHPQLHYESKLYMLLQGGT 63
Query: 132 GIPQAYYFGQEGLHNILVIDLLGPSLEDLFDWCGRRFSIKTVVHVAIQMITLIEELHDHD 191
G+P ++G EG +N++VIDLLGPSLEDLF++C R+ S+KTV+ +A Q+I +E +H
Sbjct: 64 GVPNLKWYGVEGDYNVMVIDLLGPSLEDLFNYCNRKLSLKTVLMLADQLINRVEFMHTRG 123
Query: 192 LIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTARYMS 251
++RDIKPDNFL+G + AN V++IDFG+ K YRD +T +HIPYRE K+L+GTARY S
Sbjct: 124 FLHRDIKPDNFLMGLGRK--ANQVYIIDFGLGKKYRDLQTHRHIPYRENKNLTGTARYAS 181
Query: 252 INTHLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKAANNKLKYEKIGEKKRSTNVYDLS 311
+NTHLG EQSRRDD+EALG+V YFL+G LPWQGLKA K KY++I EKK +T + L
Sbjct: 182 VNTHLGVEQSRRDDLEALGYVLMYFLKGSLPWQGLKAGTKKQKYDRISEKKVATPIEVLC 241
Query: 312 QGLPVQFGRYLEIVRNLGFEETPDYEGYRKLLLSVLDELGQKLDGEYDWMKL 363
+ P +F Y R+L F++ PDY ++L + G + D +DW L
Sbjct: 242 KNQPSEFVSYFRYCRSLRFDDKPDYSYLKRLFRDLFIREGYQFDYVFDWTVL 293
>At5g44100 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 476
Score = 298 bits (762), Expect = 2e-80
Identities = 146/292 (50%), Positives = 200/292 (68%), Gaps = 2/292 (0%)
Query: 72 IVGLHYKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPRKTDAPQLKDEYRTYKILSGSE 131
++G +K+GKKIG GSFG L+ GVN+ VA+K E KT PQL E + Y +L G
Sbjct: 4 VIGGKFKLGKKIGSGSFGELYLGVNVQTGEEVAVKLENVKTKHPQLHYESKLYMLLQGGS 63
Query: 132 GIPQAYYFGQEGLHNILVIDLLGPSLEDLFDWCGRRFSIKTVVHVAIQMITLIEELHDHD 191
GIP +FG EG ++++VIDLLGPSLEDLF++C R+ ++KTV+ +A Q++ +E +H
Sbjct: 64 GIPNIKWFGVEGDYSVMVIDLLGPSLEDLFNYCNRKLTLKTVLMLADQLLNRVEFMHTRG 123
Query: 192 LIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTARYMS 251
++RDIKPDNFL+G + AN V++IDFG+ K YRD +T +HIPYRE K+L+GTARY S
Sbjct: 124 FLHRDIKPDNFLMGLGRK--ANQVYIIDFGLGKKYRDLQTHKHIPYRENKNLTGTARYAS 181
Query: 252 INTHLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKAANNKLKYEKIGEKKRSTNVYDLS 311
+NTHLG EQSRRDD+E+LG+V YFL+G LPWQGLKA K KY++I EKK ST + L
Sbjct: 182 VNTHLGVEQSRRDDLESLGYVLMYFLKGSLPWQGLKAGTKKQKYDRISEKKVSTPIEVLC 241
Query: 312 QGLPVQFGRYLEIVRNLGFEETPDYEGYRKLLLSVLDELGQKLDGEYDWMKL 363
+ P +F Y R+L F++ PDY ++L + G + D +DW L
Sbjct: 242 KNQPSEFVSYFHYCRSLRFDDKPDYSYLKRLFRDLFIREGYQFDYVFDWTVL 293
>At4g28880 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 307
Score = 296 bits (757), Expect = 7e-80
Identities = 155/290 (53%), Positives = 199/290 (68%), Gaps = 4/290 (1%)
Query: 72 IVGLHYKIGKKIGEGSFGVLFEGVNMINNVPVAIKF-EPRKTDAPQLKDEYRTYKILSGS 130
I+G YK+G+KIG GSFG +F G + ++V V + F E KT PQL E + Y+IL G
Sbjct: 4 IIGGKYKLGRKIGGGSFGEIFLGF-VFSSVLVPLVFRENSKTKHPQLLYEAKLYRILEGG 62
Query: 131 EGIPQAYYFGQEGLHNILVIDLLGPSLEDLFDWCGRRFSIKTVVHVAIQMITLIEELHDH 190
GIP+ +FG +G N LV+DLLGPSLEDLF +CGR+FS KTV+ +A QM+T IE +H
Sbjct: 63 SGIPRIKWFGVDGTENALVMDLLGPSLEDLFVYCGRKFSPKTVLMLADQMLTRIEFVHSK 122
Query: 191 DLIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTARYM 250
++RDIKPDNFL+G + AN V+LIDFG+AK YRD T +HIPYRE K+L+GTARY
Sbjct: 123 GYLHRDIKPDNFLMGLGRK--ANQVYLIDFGLAKRYRDANTNRHIPYRENKNLTGTARYA 180
Query: 251 SINTHLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKAANNKLKYEKIGEKKRSTNVYDL 310
S NTHLG EQSRRDD+E+LG+V YFLRG LPWQGLKA + K KY+KI EKK ST + L
Sbjct: 181 SCNTHLGIEQSRRDDLESLGYVLLYFLRGSLPWQGLKAVDKKQKYDKICEKKISTPIEVL 240
Query: 311 SQGLPVQFGRYLEIVRNLGFEETPDYEGYRKLLLSVLDELGQKLDGEYDW 360
+ PV+F Y L F++ PDY ++L + G + D +DW
Sbjct: 241 CKNHPVEFASYFHYCHTLTFDQRPDYGFLKRLFRDLFSREGYEFDYIFDW 290
>At4g28860 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 307
Score = 294 bits (753), Expect = 2e-79
Identities = 152/289 (52%), Positives = 193/289 (66%), Gaps = 2/289 (0%)
Query: 72 IVGLHYKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPRKTDAPQLKDEYRTYKILSGSE 131
I+G YK+G+KIG GSFG +F GV + + E KT PQL E + Y+ L G
Sbjct: 4 IIGGKYKLGRKIGGGSFGEIFLGVFSLILEFCSSSLENSKTKHPQLLYEAKLYRTLEGGS 63
Query: 132 GIPQAYYFGQEGLHNILVIDLLGPSLEDLFDWCGRRFSIKTVVHVAIQMITLIEELHDHD 191
GIP+ +FG +G N LV+DLLGPSLEDLF +CGR+FS KTV+ +A QM+T IE +H
Sbjct: 64 GIPRIRWFGVDGTENALVMDLLGPSLEDLFVYCGRKFSPKTVLMLADQMLTRIEYVHSKG 123
Query: 192 LIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTARYMS 251
++RDIKPDNFL+G + AN V+LIDFG+AK YRD T +HIPYRE K+L+GTARY S
Sbjct: 124 YLHRDIKPDNFLMGLGRK--ANQVYLIDFGLAKRYRDANTNRHIPYRENKNLTGTARYAS 181
Query: 252 INTHLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKAANNKLKYEKIGEKKRSTNVYDLS 311
NTHLG EQ RRDD+E+LG+V YFLRG LPWQGLKA + K KY+KI EKK ST + L
Sbjct: 182 CNTHLGIEQGRRDDLESLGYVLLYFLRGSLPWQGLKAVDKKQKYDKICEKKISTPIEVLC 241
Query: 312 QGLPVQFGRYLEIVRNLGFEETPDYEGYRKLLLSVLDELGQKLDGEYDW 360
+ PV+F Y L F++ PDY ++L + G + D YDW
Sbjct: 242 KSHPVEFASYFHYCHTLTFDQRPDYGFLKRLFRDLFSREGYEFDYIYDW 290
>SPAC23C4.12 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 400
Score = 293 bits (750), Expect = 4e-79
Identities = 148/291 (50%), Positives = 200/291 (67%), Gaps = 4/291 (1%)
Query: 73 VGLHYKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPRKTDAPQLKDEYRTYKILSGSEG 132
+G Y+IG+KIG GSFG ++ G+N +N VA+K EP K QL+ E+R Y IL G+ G
Sbjct: 8 IGNKYRIGRKIGSGSFGQIYLGLNTVNGEQVAVKLEPLKARHHQLEYEFRVYNILKGNIG 67
Query: 133 IPQAYYFGQEGLHNILVIDLLGPSLEDLFDWCGRRFSIKTVVHVAIQMITLIEELHDHDL 192
IP +FG +N +V+DLLGPSLEDLF +CGR+F++KTV+ +A Q+I+ IE +H
Sbjct: 68 IPTIRWFGVTNSYNAMVMDLLGPSLEDLFCYCGRKFTLKTVLLLADQLISRIEYVHSKSF 127
Query: 193 IYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTARYMSI 252
++RDIKPDNFL+ + +N+V +IDFG+AK YRD KT HIPYR+ K+L+GTARY SI
Sbjct: 128 LHRDIKPDNFLMKK----HSNVVTMIDFGLAKKYRDFKTHVHIPYRDNKNLTGTARYASI 183
Query: 253 NTHLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKAANNKLKYEKIGEKKRSTNVYDLSQ 312
NTH+G EQSRRDD+E+LG+V YF RG LPWQGL+A + KY++I + K T + L +
Sbjct: 184 NTHIGIEQSRRDDLESLGYVLLYFCRGSLPWQGLQADTKEQKYQRIRDTKIGTPLEVLCK 243
Query: 313 GLPVQFGRYLEIVRNLGFEETPDYEGYRKLLLSVLDELGQKLDGEYDWMKL 363
GLP +F Y+ R L F E P+Y RKL +L G + D +DWM L
Sbjct: 244 GLPEEFITYMCYTRQLSFTEKPNYAYLRKLFRDLLIRKGYQYDYVFDWMIL 294
>7292798 [T] KOG1163 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 337
Score = 286 bits (731), Expect = 7e-77
Identities = 160/333 (48%), Positives = 206/333 (61%), Gaps = 13/333 (3%)
Query: 72 IVGLHYKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPRKTDAPQLKDEYRTYKILSGSE 131
IVG Y++ +KIG GSFG ++ G+++ + VAIK E PQL E + Y+ILSG
Sbjct: 15 IVGGKYRVIRKIGSGSFGDIYLGMSIQSGEEVAIKMESAHARHPQLLYEAKLYRILSGGV 74
Query: 132 GIPQAYYFGQEGLHNILVIDLLGPSLEDLFDWCGRRFSIKTVVHVAIQMITLIEELHDHD 191
G P+ + G+E N LV+DLLGPSLEDLF++C R F+IKTV+ + QMI +E +H
Sbjct: 75 GFPRIRHHGKEKNFNTLVMDLLGPSLEDLFNFCTRHFTIKTVLMLVDQMIGRLEYIHLKC 134
Query: 192 LIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTARYMS 251
I+RDIKPDNFL+G N + LIDFG+AK +RDP T+ HI YRE K+L+GTARY S
Sbjct: 135 FIHRDIKPDNFLMGIGRH--CNKLFLIDFGLAKKFRDPHTRHHIVYREDKNLTGTARYAS 192
Query: 252 INTHLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKAANNKLKYEKIGEKKRSTNVYDLS 311
IN HLG EQSRRDDME+LG+V YF RG LPWQG+KA + KYEKI EKK ST + L
Sbjct: 193 INAHLGIEQSRRDDMESLGYVMMYFNRGVLPWQGMKANTKQQKYEKISEKKMSTPIEVLC 252
Query: 312 QGLPVQFGRYLEIVRNLGFEETPDYEGYRKLLLSVLDELGQKLDGEYDWMKLNGGRGWDL 371
+G P +F YL R+L FEE PDY R+L + L + D YDW L
Sbjct: 253 KGSPAEFSMYLNYCRSLRFEEQPDYMYLRQLFRILFRTLNHQYDYIYDWTML-------- 304
Query: 372 AINKKPNLHGYGHPTPPNEKSKRHRNKFNQVPL 404
K+ G +P E+ + + K N PL
Sbjct: 305 ---KQKTHQGQPNPAILLEQLDKDKEKQNGKPL 334
>7292762 [T] KOG1163 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 344
Score = 251 bits (642), Expect = 1e-66
Identities = 131/285 (45%), Positives = 184/285 (63%), Gaps = 2/285 (0%)
Query: 76 HYKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPRKTDAPQLKDEYRTYKILSGSEGIPQ 135
+YK+ +KIG GSFG ++ G+ + + VAIK E K PQL E R Y+ L + G+P+
Sbjct: 16 NYKVVRKIGCGSFGDIYLGIYIHSGERVAIKVESSKVRHPQLNYERRIYRALRPAHGLPR 75
Query: 136 AYYFGQEGLHNILVIDLLGPSLEDLFDWCGRRFSIKTVVHVAIQMITLIEELHDHDLIYR 195
YF +E + +V+DLLGPSLE LF +C R F+IKTV+ +A QM+ +E +H+ ++R
Sbjct: 76 IRYFHKEEHYQAMVMDLLGPSLERLFQFCERAFTIKTVLLLAEQMLRRVEYVHNRGFLHR 135
Query: 196 DIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTARYMSINTH 255
DIKPDNFL+G + V+LIDFG++K Y D T HIPYRE++SL+GTARY SI H
Sbjct: 136 DIKPDNFLMGLGTM--SKQVYLIDFGLSKKYLDITTGVHIPYREERSLTGTARYASIGAH 193
Query: 256 LGREQSRRDDMEALGHVFFYFLRGQLPWQGLKAANNKLKYEKIGEKKRSTNVYDLSQGLP 315
G E +RRDDM A+G+V YF RG LPWQ LKA+ + KYE+I EKK S ++ L +G P
Sbjct: 194 AGVESARRDDMVAVGYVLMYFNRGSLPWQDLKASTKQQKYERIHEKKISVSIEVLCEGFP 253
Query: 316 VQFGRYLEIVRNLGFEETPDYEGYRKLLLSVLDELGQKLDGEYDW 360
+F YL R +GF + P+Y+ ++ + + L + YDW
Sbjct: 254 CEFTMYLNYCRGMGFYDKPNYDFICRMFRMLRNGLNLRPGLIYDW 298
>ECU03g0910 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 327
Score = 246 bits (627), Expect = 8e-65
Identities = 130/288 (45%), Positives = 184/288 (63%), Gaps = 10/288 (3%)
Query: 78 KIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPRKTDAPQLKDEYRTYKILSGSEGIPQAY 137
K+ +KI G+FG +F G N + N VA+K E +K QLK EY YK L G+ P+ Y
Sbjct: 32 KLVQKIASGAFGDIFIGQNTVTNQTVAVKLE-KKAHYGQLKHEYGVYKALGGTR-TPRIY 89
Query: 138 YFGQEGLHNI----LVIDLLGPSLEDLFDWCGRRFSIKTVVHVAIQMITLIEELHDHDLI 193
+G+ N+ LV++L+G SLE LF C RRFS+KTV+ + +M+ +E LH + +
Sbjct: 90 EYGKILYENVYVNGLVMELMGKSLEQLFVTCSRRFSLKTVLMLGERMVDNVEYLHHRNYV 149
Query: 194 YRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTARYMSIN 253
+RDIKPDNF+ + ++LID+G+AK +R+P T +H R KSL+GTARY S+
Sbjct: 150 HRDIKPDNFVF----DVQGDRLYLIDYGLAKEFRNPMTFKHREMRTDKSLTGTARYASLR 205
Query: 254 THLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKAANNKLKYEKIGEKKRSTNVYDLSQG 313
TH G EQSRRDD+E++G YFL+G+LPWQGLKA + KY++I E K S ++Y+L G
Sbjct: 206 THQGYEQSRRDDLESVGFCMVYFLKGRLPWQGLKAKTKQEKYDRIRESKESISLYELCMG 265
Query: 314 LPVQFGRYLEIVRNLGFEETPDYEGYRKLLLSVLDELGQKLDGEYDWM 361
LP + + VRNLG+E+ P+Y R LL L + G + DG +DWM
Sbjct: 266 LPKEIHSFCFYVRNLGYEDMPNYAYLRTLLSDALRQRGLRSDGVFDWM 313
>At4g08800 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 285
Score = 243 bits (619), Expect = 7e-64
Identities = 124/291 (42%), Positives = 177/291 (60%), Gaps = 34/291 (11%)
Query: 73 VGLHYKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPRKTDAPQLKDEYRTYKILSGSEG 132
+G +++G+KIG G+FG ++ G ++ +N VAIKFE KT PQL E R Y++L G
Sbjct: 5 IGNKFRLGRKIGSGAFGEIYLGTDVQSNEDVAIKFESVKTVHPQLAYESRIYRVLQSGNG 64
Query: 133 IPQAYYFGQEGLHNILVIDLLGPSLEDLFDWCGRRFSIKTVVHVAIQMITLIEELHDHDL 192
IP ++G +FS+KTV+ +A QMI +E +H
Sbjct: 65 IPNMKWYG--------------------------KFSLKTVLMLADQMINRLEFIHSKSF 98
Query: 193 IYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTARYMSI 252
++RDIKPDNFL+G+ + D FG+A+ YRD + +HIPYRE KSL+GT Y S+
Sbjct: 99 LHRDIKPDNFLMGKAGKSD--------FGLARKYRDSSSYRHIPYRENKSLTGTPAYASL 150
Query: 253 NTHLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKAANNKLKYEKIGEKKRSTNVYDLSQ 312
NTHLG EQSRRDD+E+LG++ YFL+G LPW+GLKA N K KY+KI EKK ST++ L +
Sbjct: 151 NTHLGIEQSRRDDVESLGYILMYFLKGSLPWKGLKAGNKKQKYDKISEKKVSTSIETLCE 210
Query: 313 GLPVQFGRYLEIVRNLGFEETPDYEGYRKLLLSVLDELGQKLDGEYDWMKL 363
G P++F Y+ R+L F++ PDY ++L + G + D +DW L
Sbjct: 211 GHPIEFATYIHYCRSLRFDDKPDYAYLKRLFRDLFIREGFQFDFVFDWTVL 261
>7296752 [T] KOG1163 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 477
Score = 242 bits (618), Expect = 9e-64
Identities = 136/327 (41%), Positives = 190/327 (57%), Gaps = 4/327 (1%)
Query: 72 IVGLHYKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPRKTDAPQLKDEYRTYKILSGSE 131
IV Y++ K+IG GSFG LF+ + + VAIK E P L E R Y IL G
Sbjct: 63 IVAGKYRLLKRIGNGSFGELFQAEGLKYHEKVAIKLESSTVKHPLLPREARIYGILQGGL 122
Query: 132 GIPQAYYFGQEGLHNILVIDLLGPSLEDLFDWCGRRFSIKTVVHVAIQMITLIEELHDHD 191
GIP ++ EG +N++V+DLLGP+LEDL + C R FS+KT + +A Q++ +E LH
Sbjct: 123 GIPHVKHYATEGAYNVMVMDLLGPTLEDLLNLCSRSFSMKTTLMLADQILARVELLHRRC 182
Query: 192 LIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTARYMS 251
I+RDIKPDNFL+G V++IDFG+AK + +T++HI Y E + L GTARY S
Sbjct: 183 FIHRDIKPDNFLMGLNRH--QTQVYMIDFGLAKKFYSLRTQKHIGYTENRDLVGTARYAS 240
Query: 252 INTHLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKAANNKLKYEKIGEKKRSTNVYDLS 311
+ H EQSRRDD+E++G++ YF RG+LPWQG++A + KYEKI E K + + L
Sbjct: 241 VRAHYA-EQSRRDDLESVGYLLLYFQRGRLPWQGIRAQSQAQKYEKIAEYKANIPLQQLC 299
Query: 312 QGLPVQFGRYLEIVRNLGFEETPDYEGYRKLLLSVLDELGQKLDGEYDWMKLNGGRGWDL 371
GLPV+F YL+ R L F E PDY ++L + + D +DW+ L +
Sbjct: 300 SGLPVEFFMYLKYCRKLHFAEKPDYVYLQQLFKVLFRNQYKVCDFLFDWVVLK-RESPEQ 358
Query: 372 AINKKPNLHGYGHPTPPNEKSKRHRNK 398
+K G + +RHRNK
Sbjct: 359 QSQQKGRERDRGGKRNVVVQKERHRNK 385
>7295933 [T] KOG1163 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 319
Score = 229 bits (584), Expect = 8e-60
Identities = 126/280 (45%), Positives = 166/280 (59%), Gaps = 2/280 (0%)
Query: 81 KKIGEGSFGVLFEGVNMINNVPVAIKFEPRKTDAPQLKDEYRTYKILSGSEGIPQAYYFG 140
+K+G GSFG ++E +M + + VA+K E + L E Y +L GIP Y F
Sbjct: 19 RKLGSGSFGDIYEAKHMGSGLHVALKVERKNAGQSHLSIESTVYNLLRHGMGIPMTYQFF 78
Query: 141 QEGLHNILVIDLLGPSLEDLFDWCGRRFSIKTVVHVAIQMITLIEELHDHDLIYRDIKPD 200
H++LV++LLGPSLE LF C RRFS+KTV+ +A QM+ +E LH H ++RDIKP+
Sbjct: 79 SNRRHDVLVMELLGPSLETLFTMCNRRFSMKTVLMLADQMVDRLEYLHLHHYVHRDIKPE 138
Query: 201 NFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTARYMSINTHLGREQ 260
NFL+G + +HLIDFG++K Y D K +H+P R +GTARY S+N + Q
Sbjct: 139 NFLMGVGLT--RHRLHLIDFGLSKRYWDMKENRHVPQRRGTKWAGTARYASVNALCCKVQ 196
Query: 261 SRRDDMEALGHVFFYFLRGQLPWQGLKAANNKLKYEKIGEKKRSTNVYDLSQGLPVQFGR 320
SRRDD+E++G+V Y LRG LPWQGL + K E I E K ST L G P +F
Sbjct: 197 SRRDDLESVGYVLIYLLRGSLPWQGLLPNSKLQKAEMILEMKLSTLPNSLCAGYPNEFYN 256
Query: 321 YLEIVRNLGFEETPDYEGYRKLLLSVLDELGQKLDGEYDW 360
Y+ R LGFEE PDY R LS+L L D YDW
Sbjct: 257 YIIYTRQLGFEEEPDYRMIRCTFLSLLFNLKFTNDLIYDW 296
>7298405 [T] KOG1163 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 367
Score = 214 bits (544), Expect = 3e-55
Identities = 115/292 (39%), Positives = 167/292 (56%), Gaps = 25/292 (8%)
Query: 72 IVGLHYKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPRKTDAPQLKDEYRTYKILSGSE 131
++G Y++ K IG GSFG ++ G+++ + VAIK E PQL E + Y+ L+
Sbjct: 22 LIGGKYRLVKPIGSGSFGDIYLGLSITDGSEVAIKVEKNDAKYPQLIYEAKVYEQLARCP 81
Query: 132 GIPQAYYFGQEGLHNILVIDLLGPSLEDLFDWCGRRFSIKTVVHVAIQMITLIEELHDHD 191
G P ++G C + ++ TV+ + Q++ IE +H+
Sbjct: 82 GFPTLLHYG-----------------------CEKNYNAMTVLMLTDQLLMRIECVHERG 118
Query: 192 LIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTARYMS 251
I+RDIKPDNFL+G N ++LIDFG++K Y+D +++ HIPYR ++L+GT RY S
Sbjct: 119 FIHRDIKPDNFLMGLDRH--CNKLYLIDFGLSKRYKDIESEIHIPYRTDRNLTGTVRYAS 176
Query: 252 INTHLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKAANNKLKYEKIGEKKRSTNVYDLS 311
IN +G EQSRRDDME++ + YF G+LPWQG+ AAN K KYEKI EKK S + L
Sbjct: 177 INAQIGVEQSRRDDMESMSYCLMYFNLGKLPWQGITAANKKQKYEKILEKKTSVTIAQLC 236
Query: 312 QGLPVQFGRYLEIVRNLGFEETPDYEGYRKLLLSVLDELGQKLDGEYDWMKL 363
+G P +F + VRNLGF+E PD+ R++ + L D YDW L
Sbjct: 237 KGFPSEFCLLMTYVRNLGFKEPPDHTYLRQIFRILFRSLNHHYDYIYDWTAL 288
>At2g25760 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 304
Score = 192 bits (489), Expect = 8e-49
Identities = 100/279 (35%), Positives = 165/279 (58%), Gaps = 13/279 (4%)
Query: 77 YKIGKKIGEGSFGVLFEGVNMINN----------VPVAIKFEPRKTDAPQLKD--EYRTY 124
YK+ +K+G+G FG ++ G M + + VA+KFE R + E++ Y
Sbjct: 2 YKLDRKLGKGGFGQVYVGRKMGTSTSNARFGPGALEVALKFEHRTSKGCNYGPPYEWQVY 61
Query: 125 KILSGSEGIPQAYYFGQEGLHNILVIDLLGPSLEDLFDWCGRRFSIKTVVHVAIQMITLI 184
L GS G+P+ ++ G++G ++V+D+LGPSL D+++ + S + V +AI+ I+++
Sbjct: 62 NALGGSHGVPRVHFKGRQGDFYVMVMDILGPSLWDVWNSTTQAMSTEMVACIAIEAISIL 121
Query: 185 EELHDHDLIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSL- 243
E++H ++ D+KP+NFL+G P P+ + L+D G+A +RD T H+ Y ++ +
Sbjct: 122 EKMHSRGYVHGDVKPENFLLGPPGTPEEKKLFLVDLGLASKWRDTATGLHVEYDQRPDVF 181
Query: 244 SGTARYMSINTHLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKAANNKLKYEKIGEKKR 303
GT RY S++ HLGR SRRDD+E+L + + LRG+LPWQG + + K K + +KK
Sbjct: 182 RGTVRYASVHAHLGRTCSRRDDLESLAYTLVFLLRGRLPWQGYQVGDTKNKGFLVCKKKM 241
Query: 304 STNVYDLSQGLPVQFGRYLEIVRNLGFEETPDYEGYRKL 342
+T+ L P F +++E V NL F+E PDY Y L
Sbjct: 242 ATSPETLCCFCPQPFRQFVEYVVNLKFDEEPDYAKYVSL 280
>At5g18190 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 691
Score = 185 bits (470), Expect = 1e-46
Identities = 102/285 (35%), Positives = 166/285 (57%), Gaps = 18/285 (6%)
Query: 77 YKIGKKIGEGSFGVLFEGVNMINN--------VPVAIKFEPRKTDAPQLKD--EYRTYKI 126
YK +K+G+G FG +F G + + VA+KFE R + E++ Y
Sbjct: 130 YKTERKLGKGGFGQVFVGRRVSGGSDRIGADAIEVALKFEHRNSKGCNFGPPYEWQVYNT 189
Query: 127 LSGSEGIPQAYYFGQEGLHNILVIDLLGPSLEDLFDWCGRRFSIKTVVHVAIQMITLIEE 186
L+G G+P ++ G++G ILV+D+LGPSL D+++ G+ S V +A++ I+++E+
Sbjct: 190 LNGCYGVPAVHHKGRQGDFYILVMDMLGPSLWDVWNSSGQSMSPNMVACIAVESISILEK 249
Query: 187 LHDHDLIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSL-SG 245
LH ++ D+KP+NFL+G+P D ++LID G+A ++D + QH+ Y ++ + G
Sbjct: 250 LHMKGFVHGDVKPENFLLGQPGTADEKKLYLIDLGLASKWKDSHSGQHVEYDQRPDVFRG 309
Query: 246 TARYMSINTHLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKAANNKLKYEKIGEKKRST 305
T RY S++ HLGR SRRDD+E+L + + L+G+LPWQG + N K + +KK ST
Sbjct: 310 TIRYASVHAHLGRTGSRRDDLESLAYTLIFLLKGRLPWQGYQGDN---KSFLVCKKKMST 366
Query: 306 NVYDLSQGLPVQFGRYLEIVRNLGFEETPDYEGYRKLLLSVLDEL 350
+ + P F +LE V N+ F+E P+Y L+S+ D L
Sbjct: 367 SPELMCCFCPPPFKLFLEAVTNMKFDEEPNY----AKLISIFDSL 407
>At3g13670 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 703
Score = 184 bits (467), Expect = 3e-46
Identities = 98/285 (34%), Positives = 167/285 (58%), Gaps = 15/285 (5%)
Query: 77 YKIGKKIGEGSFGVLFEGVNMINN---------VPVAIKFEPRKTDAPQL--KDEYRTYK 125
YK+ +K+G+G FG +F G + + VA+KFE R + E++ Y
Sbjct: 137 YKVERKLGKGGFGQVFVGRRISGGNDRSAGASILEVALKFEHRSSKGCNYGPPHEWQVYN 196
Query: 126 ILSGSEGIPQAYYFGQEGLHNILVIDLLGPSLEDLFDWCGRRFSIKTVVHVAIQMITLIE 185
L GS G+P+ ++ G++G + ++V+D+LGPSL DL++ G+ S + V +A++ ++++E
Sbjct: 197 TLGGSHGVPRVHFKGRQGDYYVMVMDMLGPSLWDLWNTSGQAMSSEMVACIAVESLSILE 256
Query: 186 ELHDHDLIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSL-S 244
++H ++ D+KP+NFL+G+P+ + L+D G+A +R+ + QH+ Y ++ +
Sbjct: 257 KMHAKGYVHGDVKPENFLLGQPSTSQEKKLFLVDLGLATKWREGGSGQHVEYDQRPDMFR 316
Query: 245 GTARYMSINTHLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKAANNKLKYEKIGEKKRS 304
GT RY S + HLGR SRRDD+E+L + + RG+LPWQG + N K + +KK +
Sbjct: 317 GTVRYASAHAHLGRTASRRDDLESLAYTLIFLHRGRLPWQGYQGDN---KSFLVCKKKMA 373
Query: 305 TNVYDLSQGLPVQFGRYLEIVRNLGFEETPDYEGYRKLLLSVLDE 349
T+ L P F ++LEIV N+ F+E P+Y L +L E
Sbjct: 374 TSPDMLCCFCPPPFKQFLEIVVNMKFDEEPNYGKLVSLFQDLLGE 418
>At3g03940 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 701
Score = 176 bits (446), Expect = 8e-44
Identities = 99/285 (34%), Positives = 162/285 (56%), Gaps = 18/285 (6%)
Query: 77 YKIGKKIGEGSFGVLFEGVNMINN--------VPVAIKFEPRKTDAPQLKD--EYRTYKI 126
YK +K+G+G FG ++ G + + VA+K E R + E++ Y
Sbjct: 140 YKTERKLGKGGFGQVYVGRRVSGGSDRIGADAIEVALKLEHRNSKGCNFGPPYEWQVYNT 199
Query: 127 LSGSEGIPQAYYFGQEGLHNILVIDLLGPSLEDLFDWCGRRFSIKTVVHVAIQMITLIEE 186
L+ GIP ++ G++G ILV+D+LGPSL D+++ + S V +A++ I+++E+
Sbjct: 200 LNSCYGIPAVHHKGRQGDFYILVMDMLGPSLWDVWNSLAQSMSPNMVACIAVEAISILEK 259
Query: 187 LHDHDLIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSL-SG 245
LH ++ D+KP+NFL+G+P D ++LID G+A ++D + QH+ Y ++ + G
Sbjct: 260 LHMKGFVHGDVKPENFLLGQPGTADEKKLYLIDLGLASRWKDSHSGQHVEYDQRPDVFRG 319
Query: 246 TARYMSINTHLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKAANNKLKYEKIGEKKRST 305
T RY S + HLGR SRRDD+E+L + + +RG+LPWQG + N K + +KK ST
Sbjct: 320 TIRYASCHAHLGRTGSRRDDLESLAYTLIFLMRGRLPWQGYQGDN---KSFLVCKKKMST 376
Query: 306 NVYDLSQGLPVQFGRYLEIVRNLGFEETPDYEGYRKLLLSVLDEL 350
+ + P F +LE V N+ F+E P+Y L+S+ D L
Sbjct: 377 SPELMCCFCPPPFKLFLEAVTNMKFDEEPNY----AKLISIFDTL 417
>CE06325 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 776
Score = 151 bits (382), Expect = 2e-36
Identities = 94/291 (32%), Positives = 153/291 (52%), Gaps = 10/291 (3%)
Query: 72 IVGLHYKIGKKIGEGSFGVLFEGVNMINNVP-VAIKFEPRKTDAPQLKDEYRTYKILSGS 130
++ +KI KIG G FG ++E ++ N+ VAIK E K LK E + L G
Sbjct: 15 VIRERWKIKAKIGGGGFGEIYEATDVQNHHERVAIKVESSKATKQVLKMEVAVLRRLQGK 74
Query: 131 EGIPQAYYFGQEGLHNILVIDLLGPSLEDLFDWCGRR-FSIKTVVHVAIQMITLIEELHD 189
+ + Y G+ N LV+ L G +L DL ++ F++ T V V IQ++ I E+H
Sbjct: 75 KHACKFYGCGRNDKFNYLVMSLQGKNLADLRREAPKQCFNLSTAVRVGIQILNGIREIHS 134
Query: 190 HDLIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTARY 249
++RD+KP NF +GR +Q N V+++DFG+A+ Y + K + P R GT RY
Sbjct: 135 IGFLHRDVKPSNFAMGRTSQTMRN-VYMLDFGLARQYLNAKGEIRSP-RSAAGFRGTVRY 192
Query: 250 MSINTHLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKAANNKLKYEKIGEKKRSTNVYD 309
++ H +E R+DD+ +L ++ FL+GQLPW+ +K +++G+ K ++
Sbjct: 193 AAVTAHKNKEMGRQDDLWSLFYMLTEFLQGQLPWRKIK------DKDEVGKMKEEADLVV 246
Query: 310 LSQGLPVQFGRYLEIVRNLGFEETPDYEGYRKLLLSVLDELGQKLDGEYDW 360
L P + ++ ++ LG+ +TPDY LL ++ E D YDW
Sbjct: 247 LLDDCPHEMHLFVAHLKVLGYADTPDYVYLESLLNKIVAENEISWDEPYDW 297
>ECU11g1980 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 318
Score = 143 bits (361), Expect = 6e-34
Identities = 101/290 (34%), Positives = 156/290 (52%), Gaps = 19/290 (6%)
Query: 75 LHYKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPRKTDAPQ-----LKDEYRTYKILSG 129
+ Y I ++IG+G FG ++E + A+K E T+AP+ + +E + Y L G
Sbjct: 6 MDYTICREIGKGGFGKVYEVKKKADQKSYALKIE---TNAPKAGRNSIINEIQAYSELQG 62
Query: 130 SEGIPQAYYFGQ-EGLHNILVIDLLGPSLEDLFDWCGRRFSIKTVVHVAIQMITLIEELH 188
E IP+ G EGL LV+ LL SL+DL + R F+ K+ V +++ IE +H
Sbjct: 63 CEKIPRLVDHGSYEGL-TFLVLPLLKYSLKDLLERHPRFFTKKSATIVGKKLLNAIEFIH 121
Query: 189 DHDLIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTAR 248
++RDIKP+N + G N+ ++L+DFGM+ Y HIP KS+SGT
Sbjct: 122 GKGRLHRDIKPENVMFGHNNR-----IYLVDFGMSAPYLRGDGS-HIPEVGGKSVSGTLW 175
Query: 249 YMSINTHLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKAANNKLKYEKIGEKKRSTNVY 308
YMSINTH G EQSRRDD+E+L ++ + +LPW A+ +K + + E K + +VY
Sbjct: 176 YMSINTHRGIEQSRRDDLESLFYLLILLYKSRLPWMEPGASVSKKQEARTKEIKENLSVY 235
Query: 309 DLSQGL--PVQFGRYLEIVRNLGFEETPDYEGYRKLLLSVLDELGQKLDG 356
DL G+ ++ + + +L F E P+Y Y LL + ++L G
Sbjct: 236 DLCDGIHGKEHLIKFFQHISSLEFAEKPNYR-YLNSLLDKIFHSNKELQG 284
>Hs4507903 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 396
Score = 135 bits (339), Expect = 2e-31
Identities = 97/331 (29%), Positives = 166/331 (49%), Gaps = 41/331 (12%)
Query: 77 YKIGKKIGEGSFGVLF-----EGVNMINNVPVAIKFEPRKTDAPQLKDEYRTYKILSGSE 131
+K+G IG+G FG ++ ++ ++ P +K EP +D L E + Y+ + E
Sbjct: 37 WKVGLPIGQGGFGCIYLADMNSSESVGSDAPCVVKVEP--SDNGPLFTELKFYQRAAKPE 94
Query: 132 --------------GIPQAYYFGQEGLHN-------ILVIDLLGPSLEDLFDWCGRRFSI 170
G+P+ Y+G GLH+ +++D G L+ +++ +RFS
Sbjct: 95 QIQKWIRTRKLKYLGVPK--YWGS-GLHDKNGKSYRFMIMDRFGSDLQKIYEANAKRFSR 151
Query: 171 KTVVHVAIQMITLIEELHDHDLIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPK 230
KTV+ ++++++ ++E +H+H+ ++ DIK N L+ N PD V+L+D+G+A YR
Sbjct: 152 KTVLQLSLRILDILEYIHEHEYVHGDIKASNLLLNYKN-PD--QVYLVDYGLA--YRYCP 206
Query: 231 TKQHIPYRE--KKSLSGTARYMSINTHLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKA 288
H Y+E K+ GT + SI+ H G SRR D+E LG+ +L G LPW+
Sbjct: 207 EGVHKEYKEDPKRCHDGTIEFTSIDAHNGVAPSRRGDLEILGYCMIQWLTGHLPWEDNLK 266
Query: 289 ANNKLKYEKIGEKKRSTNVYDL---SQGLPVQFGRYLEIVRNLGFEETPDYEGYRKLLLS 345
++ KI ++ ++ D + P + +Y+E V+ L + E P YE R +LL
Sbjct: 267 DPKYVRDSKIRYRENIASLMDKCFPEKNKPGEIAKYMETVKLLDYTEKPLYENLRDILLQ 326
Query: 346 VLDELGQKLDGEYDWMKLNGGRGWDLAINKK 376
L +G K DG+ D + G I KK
Sbjct: 327 GLKAIGSKDDGKLDLSVVENGGLKAKTITKK 357
>CE09021 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 278
Score = 127 bits (319), Expect = 4e-29
Identities = 87/277 (31%), Positives = 139/277 (49%), Gaps = 12/277 (4%)
Query: 74 GLHYKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPRKTDAPQLKDEYRTYK--ILSGSE 131
G YK+G +G+G +G +F ++ +++ +A+K E K QLK E K + + +
Sbjct: 9 GKKYKLGPVLGDGGYGTVF--LSQDDDIKIAVKTE--KFSKSQLKIEIVVLKAAMQANCK 64
Query: 132 GIPQAYYFGQEGLH-NILVIDLLGPSLEDL-FDWCGRRFSIKTVVHVAIQMITLIEELHD 189
+ G +G + ++I LLG L L + GR+FSI T + + IQ + EELH
Sbjct: 65 HFCELVDCGTKGKDFDYMMITLLGKDLHKLRCELPGRKFSINTALRIGIQTLKACEELHR 124
Query: 190 HDLIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTARY 249
+ RD+KP NF G + + + + DFG+A+ Y D K Q IP R++ GT RY
Sbjct: 125 IGFVSRDVKPGNFAPGVKSNRQSRTIFMYDFGLARKYID-KNNQVIPTRKEVGWRGTTRY 183
Query: 250 MSINTHLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKAANNKLKYEKIGEKKRSTNVYD 309
S+N H + RRDD+E+ + RG LPW+ + ++ ++ E +T
Sbjct: 184 GSLNAHKRLDLGRRDDLESWFYGLVEMTRGTLPWRNVV---DRSSVQRAKEASHNTGRTQ 240
Query: 310 LSQGLPVQFGRYLEIVRNLGFEETPDYEGYRKLLLSV 346
P Q+ + IV + FE PDY+ KLL+ V
Sbjct: 241 FLFETPSQYDKIFTIVDSYAFESAPDYKQINKLLVEV 277
>CE16557 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 318
Score = 127 bits (318), Expect = 6e-29
Identities = 87/291 (29%), Positives = 149/291 (50%), Gaps = 13/291 (4%)
Query: 72 IVGLH--YKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPRKTDAPQLKDEYRTYKILSG 129
I+GL +++ K +G G FG +F V+M + VA+K EP+ ++ ++ E L+
Sbjct: 31 IIGLKRPFQVEKMVGGGGFGQIFRAVDMETKLVVAVKVEPKSVESGRIVLELHILVELAH 90
Query: 130 SEGIPQAYYFGQEGLHNILVIDLLGPSLEDLFDW-CGRRFSIKTVVHVAIQMITLIEELH 188
S IP+ +Y G+ G +N +V+ LLG ++ DL + GR FS +T V IQ + ++++H
Sbjct: 91 SPHIPKVHYSGEIGGYNFIVMQLLGSNITDLRKFQKGRCFSAETTARVGIQCLEGLKQIH 150
Query: 189 DHDLIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTAR 248
+ I+RDIKP N +G +++++DFGMA+ R P + P R S GT R
Sbjct: 151 ELGYIHRDIKPSNICVGIGEH--KRVLYIVDFGMARQIRFP-SGAFRPERPYASFRGTTR 207
Query: 249 YMSINTHLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKAANNKLKYEKIGEKKRSTNVY 308
Y+S+ H +EQ DD+ L G LPW+ N + +++ K+
Sbjct: 208 YVSLAAHERKEQGFADDIWCLFFSLLELAEG-LPWK------NVVDQDQVYHAKQLLLRN 260
Query: 309 DLSQGLPVQFGRYLEIVRNLGFEETPDYEGYRKLLLSVLDELGQKLDGEYD 359
S+ + FG + + + ETP+YE + +L S + + + E+D
Sbjct: 261 FQSRKMGQNFGTFPRALELIKRTETPNYENFIVILKSCSSRVNEWEEFEWD 311
>CE08953 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 346
Score = 121 bits (304), Expect = 2e-27
Identities = 87/295 (29%), Positives = 145/295 (48%), Gaps = 14/295 (4%)
Query: 72 IVGLHYKIGKKIGEGSFGVLFEGVNMINNVP---VAIKFEPRKTDAPQLKDEYRTYKILS 128
+VG Y++ +++G+G G +++ ++ + + ++F LK E + L
Sbjct: 15 VVGKKYRVIQQLGQGGCGSVYKVEDIEDKTKQYAMKVEFNSNANAGNVLKMEVQILTHLV 74
Query: 129 GSEGIPQAYYFGQEGLHNILVIDLLGPSLEDLFDWCGRRFSIKTVVHVAIQMITLIEELH 188
+ + G++ ++ +V+ LLG SLE L G F++ T + + I ++ I+++H
Sbjct: 75 SKNHVAKCMASGKKDRYSYVVMTLLGESLESLMKKHGPFFNVSTQMRIGICLLFGIKQIH 134
Query: 189 DHDLIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLY---RDPKTKQHIPYREKKSLSG 245
D I+RD+KP N +G PD ++DFG+A+ Y ++ K P REK G
Sbjct: 135 DIGFIHRDLKPANVALGNKGSPDERYFIVLDFGLARQYITDKEDGKKMRRP-REKALFRG 193
Query: 246 TARYMSINTHLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKAANNKLKYEKIGEKKRST 305
T+RY S+ H EQ R DD+ AL ++ LR QL W L ++K+ +IGE KR
Sbjct: 194 TSRYCSVAMHDRFEQGRVDDLWALIYMLAE-LRCQLAWSDL---DDKV---EIGEMKRHV 246
Query: 306 NVYDLSQGLPVQFGRYLEIVRNLGFEETPDYEGYRKLLLSVLDELGQKLDGEYDW 360
+L P+Q +++IVR F PDYE LL + K Y W
Sbjct: 247 ADQNLFAKSPIQMLEFVKIVRATQFYHRPDYEKLFNLLNDAMKSAKYKWSDPYHW 301
>CE25045 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 346
Score = 120 bits (301), Expect = 5e-27
Identities = 93/294 (31%), Positives = 146/294 (49%), Gaps = 13/294 (4%)
Query: 72 IVGLHYKIGKKIGEGSFGVLFEGVNMINNVP-VAIKFEPRKTDAPQ-LKDEYRTYKILSG 129
+VG YK+ +K+GEG G +F+ + A+K E + DA LK E + L
Sbjct: 15 VVGKRYKVVQKLGEGGCGSVFKVEDTSEKGQHYALKVEFKSQDAGNILKMEVQILSQLIS 74
Query: 130 SEGIPQAYYFGQEGLHNILVIDLLGPSLEDLFDWCGRRFSIKTVVHVAIQMITLIEELHD 189
+ + + G++ ++ +V+ LLG SL+ L G ++ T V + I ++ I+++HD
Sbjct: 75 KKHVAKCVASGKKERYSYMVMTLLGESLDSLLKKHGPFLNVSTQVRIGICILFGIKQVHD 134
Query: 190 HDLIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLY---RDPKTKQHIPYREKKSLSGT 246
++RD+KP N +G D ++DFG+A+ Y D K P REK GT
Sbjct: 135 IGYLHRDLKPANVAMGCKGSADERYFLVLDFGLARQYIADEDDGLKMRRP-REKTYFRGT 193
Query: 247 ARYMSINTHLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKAANNKLKYEKIGEKKRSTN 306
ARY S+ H EQ R DD+ AL ++ +R +L W + ++K+ +IGE KR +
Sbjct: 194 ARYCSVAMHDRYEQGRVDDLWALVYILAE-MRCRLAWHDV---DDKV---EIGEMKRKIH 246
Query: 307 VYDLSQGLPVQFGRYLEIVRNLGFEETPDYEGYRKLLLSVLDELGQKLDGEYDW 360
L PVQ +++ VR+ F PDYE KLL V+ K Y W
Sbjct: 247 DEVLFAKSPVQMLSFVKTVRSTLFYHRPDYEKLFKLLEDVMKCANYKWSDPYHW 300
>CE01965 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 424
Score = 120 bits (301), Expect = 5e-27
Identities = 88/315 (27%), Positives = 154/315 (47%), Gaps = 25/315 (7%)
Query: 72 IVGLHYKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPR-KTDAPQLKDEYRTYKILSGS 130
IVG +++ +K+GEG G ++ N+ + A+K E LK E K LSG
Sbjct: 26 IVGCSWQVIRKLGEGGCGSVYLVKNLEDETEAAMKAESNGAAGGCVLKLEVAILKKLSGK 85
Query: 131 EGIPQAYYFGQEGLHNILVIDLLGPSLEDLFDWCGRRFSIKTVVHVAIQMITLIEELHDH 190
+ Q + + +++ LLG SL + R+ ++ + V +A ++ ++++HD
Sbjct: 86 PHVCQFLFAARLTDFTYVIMTLLGESLNKIVKRIARQITVSSQVRIAANVLFCLKQIHDI 145
Query: 191 DLIYRDIKPDNFLIG-RPNQPDANMVHLIDFGMAKLY------RDPKTKQHIPYREKKSL 243
I+RD+KP N +G + N + H++DFG+A+ + + K P RE+
Sbjct: 146 GFIHRDLKPANMALGYKTNNDECRFFHVLDFGLARQFVVSQSDQPSKLMMRRP-RERSLF 204
Query: 244 SGTARYMSINTHLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKAANNKLKYEKIGEKKR 303
GT RY SI H EQ R DD+ ++ ++ LRG LPW + N+K +GE KR
Sbjct: 205 RGTTRYCSIRMHDRAEQGRVDDLWSILYLLAE-LRGPLPW---SSQNDK---RVVGEMKR 257
Query: 304 STNVYDLSQGLPVQFGRYLEIVRNLGFEETPDYEGYRKLLLSVLDELGQKLDGEYDWMKL 363
+ + Q P++F + +R+L + PDY LL+S++ + G++ W
Sbjct: 258 LHSDEVVLQNSPMEFLEIAKYLRSLTYFHRPDYHKIFMLLISIMSK------GKFSW--- 308
Query: 364 NGGRGWDLAINKKPN 378
N W++ I+ P+
Sbjct: 309 NDPFDWEMPISTPPS 323
>CE29490 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 422
Score = 119 bits (298), Expect = 1e-26
Identities = 87/315 (27%), Positives = 153/315 (47%), Gaps = 25/315 (7%)
Query: 72 IVGLHYKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPR-KTDAPQLKDEYRTYKILSGS 130
IVG +++ +K+GEG G ++ N+ + A+K E LK E K LSG
Sbjct: 19 IVGCSWQVIRKLGEGGCGSVYLVKNLEDETEAAMKAESNGAAGGCVLKLEVAILKKLSGK 78
Query: 131 EGIPQAYYFGQEGLHNILVIDLLGPSLEDLFDWCGRRFSIKTVVHVAIQMITLIEELHDH 190
+ Q + + +++ LLG SL + R+ ++ + V +A ++ ++++HD
Sbjct: 79 PHVCQFLFAARLTDFTYVIMTLLGESLNKIVKRIARQITVSSQVRIAANVLFCLKQIHDI 138
Query: 191 DLIYRDIKPDNFLIG-RPNQPDANMVHLIDFGMAKLY------RDPKTKQHIPYREKKSL 243
I+RD+KP N +G + N + H++DFG+A+ + + K P RE+
Sbjct: 139 GFIHRDLKPANMALGYKTNNDECRFFHVLDFGLARQFVVSQSDQPSKLMMRRP-RERSLF 197
Query: 244 SGTARYMSINTHLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKAANNKLKYEKIGEKKR 303
GT RY SI H EQ R DD+ ++ ++ LRG LPW +++ +GE KR
Sbjct: 198 RGTTRYCSIRMHDRAEQGRVDDLWSMVYLLAE-LRGPLPW------SSQSDKRVVGEMKR 250
Query: 304 STNVYDLSQGLPVQFGRYLEIVRNLGFEETPDYEGYRKLLLSVLDELGQKLDGEYDWMKL 363
+ + Q P++F + +R+L + PDY LL+SV+ + G++ W
Sbjct: 251 LHSDEVVLQNSPMEFLEIAKYLRSLTYFHRPDYHKIFMLLISVMSK------GKFAW--- 301
Query: 364 NGGRGWDLAINKKPN 378
N W++ I+ P+
Sbjct: 302 NDPFDWEMPISTTPS 316
>CE14562 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 488
Score = 119 bits (298), Expect = 1e-26
Identities = 92/312 (29%), Positives = 151/312 (47%), Gaps = 33/312 (10%)
Query: 72 IVGLHYKIGKKIGEGSFGVLFEGVNMIN--NVPVAIKFEPRKTDA-PQLKDEYRTYKILS 128
++ Y +K+GEG GV++E V M+ A K E D P L E++ L+
Sbjct: 13 VINRKYLAFRKLGEGGCGVIYE-VAMVKCPGRRFACKAETTVFDEDPTLPMEHKIISKLN 71
Query: 129 GSEGIPQAYYF--GQEGLHNILVIDLLGPSLEDLFDWCG-RRFSIKTVVHVAIQMITLIE 185
I GQ + +V+ LLGPSL+ + +FS + + + IQ + I+
Sbjct: 72 EKNSIHCVELIDKGQSDNYQFIVMTLLGPSLDAIRATLPTNKFSTFSTLVMGIQALDSIK 131
Query: 186 ELHDHDLIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLY----------RDPKTKQHI 235
E+HD ++RD+KP NF IG P +VH++DFG+++ Y R K ++ +
Sbjct: 132 EIHDIGFVHRDVKPANFAIGALGTPKQRLVHVLDFGISRQYLVKDGENGGLRIRKPRRIV 191
Query: 236 PYREKKSLSGTARYMSINTHLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKAANNKLKY 295
P+R GT RY S+ +EQ R DD+ +L ++ F++G LPW G+ ++
Sbjct: 192 PFR------GTLRYCSVAAQERKEQGRHDDLWSLFYMIVEFVKGSLPWTGI------MEE 239
Query: 296 EKIGEKKRSTNVYDLSQGLPVQFGRYLEIVRNLGFEETPDYEGYRKLLLSVLDELGQKLD 355
EK+ K +V +L GL + + + + L ++ PDY R LL+++
Sbjct: 240 EKVIVMKE--DVTELFNGLESECAMFAQHLSVLRYQTNPDYALLRDLLMNIFVRRNFNAQ 297
Query: 356 GEYDWMKLNGGR 367
+ DW K GGR
Sbjct: 298 MKVDWEK--GGR 307
>CE03499 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 361
Score = 118 bits (295), Expect = 3e-26
Identities = 82/290 (28%), Positives = 143/290 (49%), Gaps = 17/290 (5%)
Query: 77 YKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEP--RKTDAPQLKDEYRTYKILSGSEGIP 134
+ + KK+GEG+ G +F + A+K EP + + LK E K L S +
Sbjct: 20 FTVKKKLGEGACGQVFLVDLIQGKGSAAMKVEPLMKNKEDEILKMEVYVLKKLQNSRHVC 79
Query: 135 QAYYFGQEGLHNILVIDLLGPSLEDLFDWCG-RRFSIKTVVHVAIQMITLIEELHDHDLI 193
+ G+ + +V+ +LG + D+ R+ S + V V IQ++ ++++H+ +
Sbjct: 80 RLLGSGKTETYTYMVMSVLGKEIGDVRRRLPQRKMSAPSTVRVFIQLVKALQDMHEAGFV 139
Query: 194 YRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLS---GTARYM 250
+RD+KP N +G N+ +V++ DFG+++ P + RE ++ S GT RY
Sbjct: 140 HRDVKPSNMALGVKNE---QVVYIFDFGLSRQIMLPDASGKLKLREPRNKSMFRGTVRYC 196
Query: 251 SINTHLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKAANNKLKYEKIGEKKRSTNVYDL 310
S+N HL +EQ R DD+ + LPW+G K K E K+++T+V L
Sbjct: 197 SLNVHLHKEQGRHDDLYGALYAMIETATSTLPWKG------KPKKETSALKEKTTDV-QL 249
Query: 311 SQGLPVQFGRYLEIVRNLGFEETPDYEGYRKLLLSVLDELGQKLDGEYDW 360
+G P F +R L ++ETP Y + + L + L + G K+ ++W
Sbjct: 250 CKGCPKSFLEIATTLRKLTYKETPPYGSFMEKLKADLPK-GVKMTDPFEW 298
>CE02210 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 361
Score = 118 bits (295), Expect = 3e-26
Identities = 82/290 (28%), Positives = 143/290 (49%), Gaps = 17/290 (5%)
Query: 77 YKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEP--RKTDAPQLKDEYRTYKILSGSEGIP 134
+ + KK+GEG+ G +F + A+K EP + + LK E K L S +
Sbjct: 20 FTVKKKLGEGACGQVFLVDLIQGKGSAAMKVEPLMKNKEDEILKMEVYVLKKLQNSRHVC 79
Query: 135 QAYYFGQEGLHNILVIDLLGPSLEDLFDWCG-RRFSIKTVVHVAIQMITLIEELHDHDLI 193
+ G+ + +V+ +LG + D+ R+ S + V V IQ++ ++++H+ +
Sbjct: 80 RLLGSGKTETYTYMVMSVLGKEIGDVRRRLPQRKMSAPSTVRVFIQLVKALQDMHEAGFV 139
Query: 194 YRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLS---GTARYM 250
+RD+KP N +G N+ +V++ DFG+++ P + RE ++ S GT RY
Sbjct: 140 HRDVKPSNMALGVKNE---QVVYIFDFGLSRQIMLPDASGKLKLREPRNKSMFRGTVRYC 196
Query: 251 SINTHLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKAANNKLKYEKIGEKKRSTNVYDL 310
S+N HL +EQ R DD+ + LPW+G K K E K+++T+V L
Sbjct: 197 SLNVHLHKEQGRHDDLYGALYAMIETATSTLPWKG------KPKKETSALKEKTTDV-QL 249
Query: 311 SQGLPVQFGRYLEIVRNLGFEETPDYEGYRKLLLSVLDELGQKLDGEYDW 360
+G P F +R L ++ETP Y + + L + L + G K+ ++W
Sbjct: 250 CKGCPKSFLEIATTLRKLTYKETPPYGSFMEKLKADLPK-GVKMTDPFEW 298
>CE01289 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 263
Score = 117 bits (293), Expect = 4e-26
Identities = 73/228 (32%), Positives = 117/228 (51%), Gaps = 10/228 (4%)
Query: 135 QAYYFGQEGLHNILVIDLLGPSLEDLFDWC-GRRFSIKTVVHVAIQMITLIEELHDHDLI 193
+ ++ G+ N L++ L+G +L +L C R+FS +T + + IQMI I++LH I
Sbjct: 19 RVFFCGKAEKFNFLIMTLVGKNLSELRANCPNRKFSRRTGLQIGIQMINAIQQLHSIGFI 78
Query: 194 YRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLY-RDPKTKQHIPYREKKSLSGTARYMSI 252
+RDIKP NF I N + + + ++DFGM + Y D T+ P GT RY +
Sbjct: 79 HRDIKPANFCI---NLDNPHQLVMVDFGMCRKYLNDGGTQLRHPRWSVHGFRGTVRYAPL 135
Query: 253 NTHLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKAANNKLKYEKIGEKKRSTNVYDLSQ 312
TH GR+ R++D+E + +V L G LPW ++ + E + R+T + +
Sbjct: 136 ATHYGRDSCRKEDLETIFYVLVELLVGTLPWMTME---EHIHVEHSKQVARTTGLREFLS 192
Query: 313 GLPVQFGRYLEIVRNLGFEETPDYEGYRKLLLSVLDELGQKLDGEYDW 360
G P Q L + NL F + PDY R LL L+ + +G ++W
Sbjct: 193 GCPKQLVHILLYIDNLRFYDAPDYALIRGLLSFALENC--QHNGSFEW 238
>CE06942 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 308
Score = 115 bits (288), Expect = 2e-25
Identities = 84/296 (28%), Positives = 139/296 (46%), Gaps = 17/296 (5%)
Query: 77 YKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPRKTDAPQLKDEYRTYKILS--GSEGIP 134
+ I KK+GEG FG ++ + A+K E LK E LS G+
Sbjct: 17 WSIEKKLGEGGFGAVYRVFDATGKY--AMKVEGANEQIQVLKLEVSVLNELSKRGNRHFC 74
Query: 135 QAYYFGQEGLHNILVIDLLGPSLEDLFD-WCGRRFSIKTVVHVAIQMITLIEELHDHDLI 193
+ G+ G N +V+ L+G SL+DL G S+ + + IQ + +E+LH+ +
Sbjct: 75 KIEDKGRFGNFNYVVMTLVGKSLQDLNKAGVGGHMSMGCSIGIGIQSLEALEDLHNIGYL 134
Query: 194 YRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTARYMSIN 253
+RD+KP N+ IGRP + V+++DFGM + + P R+ GT +Y I+
Sbjct: 135 HRDVKPGNYTIGRPELNEIRKVYILDFGMCRKFTGNDGTIRKP-RQAAGFRGTVKYAPIS 193
Query: 254 THLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKAANNKLKYEKIGEKKRS--TNVYDL- 310
HL RE R+DD+E ++ G +PWQ + N ++G+ K++ N+ L
Sbjct: 194 CHLQRELCRKDDLETWMYMQVELSHGTIPWQHISDMN------QVGQAKQAIRNNLGTLF 247
Query: 311 SQGLPVQFGRYLEIVRNLGFEETPDYEGYRKLLLSVLDELGQKLDGEYDWMKLNGG 366
P QF + +V + + + P+Y+ ++ G + YDW NGG
Sbjct: 248 PPPCPQQFQDIMRMVDAMKYYDAPNYQAIYGMMRQAYGACGSNENAPYDWE--NGG 301
>CE18365 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 308
Score = 115 bits (287), Expect = 2e-25
Identities = 84/296 (28%), Positives = 139/296 (46%), Gaps = 17/296 (5%)
Query: 77 YKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPRKTDAPQLKDEYRTYKILS--GSEGIP 134
+ I KK+GEG FG ++ + A+K E LK E LS G+
Sbjct: 17 WSIEKKLGEGGFGAVYRVFDATGKY--AMKVEGANEQIQVLKLEVSVLNKLSKRGNRHFC 74
Query: 135 QAYYFGQEGLHNILVIDLLGPSLEDLFD-WCGRRFSIKTVVHVAIQMITLIEELHDHDLI 193
+ G+ G N +V+ L+G SL+DL G S+ + + IQ + +E+LH+ +
Sbjct: 75 KIEDKGRFGNFNYVVMTLVGKSLQDLNKAGVGGHMSMGCSIGIGIQSLEALEDLHNIGYL 134
Query: 194 YRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTARYMSIN 253
+RD+KP N+ IGRP + V+++DFGM + + P R+ GT +Y I+
Sbjct: 135 HRDVKPGNYTIGRPELNEIRKVYILDFGMCRKFTGNDGTIRKP-RQAAGFRGTVKYAPIS 193
Query: 254 THLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKAANNKLKYEKIGEKKRS--TNVYDL- 310
HL RE R+DD+E ++ G +PWQ + N ++G+ K++ N+ L
Sbjct: 194 CHLQRELCRKDDLETWMYMQVELSHGTIPWQYISDMN------QVGQAKQAIRNNLGSLF 247
Query: 311 SQGLPVQFGRYLEIVRNLGFEETPDYEGYRKLLLSVLDELGQKLDGEYDWMKLNGG 366
P QF + +V + + + P+Y+ ++ G + YDW NGG
Sbjct: 248 PPPCPHQFQDIMRMVDAMKYYDAPNYQAIYGMMRQAYGACGSNENAPYDWE--NGG 301
>Hs20555151 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 1270
Score = 114 bits (286), Expect = 3e-25
Identities = 85/309 (27%), Positives = 144/309 (46%), Gaps = 20/309 (6%)
Query: 95 VNMINNVPVAIKFEPRKTDAPQLKDEYRTYKILSGSEGIPQAYYFGQEGLHNILVIDLLG 154
++++ VA+K E + LK E K L G + + + G+ N +V+ L G
Sbjct: 1 MDLLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKDHVCRFIGCGRNEKFNYVVMQLQG 60
Query: 155 PSLEDLFDWCGR-RFSIKTVVHVAIQMITLIEELHDHDLIYRDIKPDNFLIGRPNQPDAN 213
+L DL R F++ T + + Q++ IE +H ++RDIKP NF +GR
Sbjct: 61 RNLADLRRSQPRGTFTLSTTLRLGKQILESIEAIHSVGFLHRDIKPSNFAMGRLPST-YR 119
Query: 214 MVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTARYMSINTHLGREQSRRDDMEALGHVF 273
+++DFG+A+ Y + T P R GT RY S+N H RE R DD+ +L ++
Sbjct: 120 KCYMLDFGLARQYTNT-TGDVRPPRNVAGFRGTVRYASVNAHKNREMGRHDDLWSLFYML 178
Query: 274 FYFLRGQLPWQGLKAANNKLKYEKIGEKKRSTNVYDLSQGLPVQFGRYLEIVRNLGFEET 333
F GQLPW+ +K E++G K L + +P +F +L+ + +L +
Sbjct: 179 VEFAVGQLPWRKIK------DKEQVGMIKEKYEHRMLLKHMPSEFHLFLDHIASLDYFTK 232
Query: 334 PDYEGYRKLLLSVLDELGQKLDGEYDWMKLNGGRGWDLAINKKPNLHGYGHPTPPNEKSK 393
PDY+ + + + E G + +DW K G D ++ + TPP + ++
Sbjct: 233 PDYQLIMSVFENSMKERGIAENEAFDWEK----AGTDALLSTSTS-------TPPQQNTR 281
Query: 394 RHRNKFNQV 402
+ F V
Sbjct: 282 QTAAMFGVV 290
>CE22097 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 468
Score = 114 bits (284), Expect = 5e-25
Identities = 81/290 (27%), Positives = 140/290 (47%), Gaps = 14/290 (4%)
Query: 77 YKIGKKIGEGSFGVLFEGVNMINN---VPVAIKFEPRKTDAPQLKDEYRTYKILSGSEGI 133
++I +G+G+ GV+++ + + ++++ + D L+ E L+ S +
Sbjct: 25 WRIKALLGKGACGVVYKVEDKNRKGYCAAMKVEYDSEEFDRT-LQLEVNVLSKLTDSRDV 83
Query: 134 PQAYYFGQEGLHNILVIDLLGPSLEDLFDWCGRRFSIKTVVHVAIQMITLIEELHDHDLI 193
+ +G+ L+ +V L G L L R F+ T + VA+ + +++LH+ +
Sbjct: 84 LKLIDYGKRKLYRYMVTTLCGKDLMALRMKIQRGFNDATAMRVAVFTLYGLKQLHEAGYV 143
Query: 194 YRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLY---RDPKTKQHIPYREKKSLSGTARYM 250
+RD+KP N + DA ++ LIDFGMA+ + D K+ P R + L GT RY
Sbjct: 144 HRDVKPGNIMTAANKGRDARVMLLIDFGMARTFVMAGDDGKKKLRPMRRRIPLRGTIRYC 203
Query: 251 SINTHLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKAANNKLKYEKIGEKKRSTNVYDL 310
S+N H +EQ R DD+ A+ + Y G LPW LK ++I K+ST L
Sbjct: 204 SMNVHERKEQGRCDDLVAMIYSIVYLTLG-LPWSNLK------DEKEIMSMKKSTKDLAL 256
Query: 311 SQGLPVQFGRYLEIVRNLGFEETPDYEGYRKLLLSVLDELGQKLDGEYDW 360
+ LP + E +R L + + P+YE LL++ + L Y+W
Sbjct: 257 FEDLPDELKSIFEYLRTLSYADRPNYEKIYNLLMAAITRLKINFLDPYEW 306
>CE02312 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 325
Score = 114 bits (284), Expect = 5e-25
Identities = 79/290 (27%), Positives = 139/290 (47%), Gaps = 17/290 (5%)
Query: 77 YKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPRKT-DAPQLKDEYRTYKILSGSEGIPQ 135
+ + K I G FG ++ N VA+K E T D+ ++ E + + GS+ P
Sbjct: 46 FVVEKMIAGGGFGQVYRARNTETQEEVAVKVERATTNDSQRMILESKVLDDMLGSKHFPN 105
Query: 136 AYYFGQEGLHNILVIDLLGPSLEDLFDWC-GRRFSIKTVVHVAIQMITLIEELHDHDLIY 194
YY G +N +V+ +LG ++ D+ ++ SI + V + IQ+I + LH ++
Sbjct: 106 VYYIGPYHSYNFIVMQMLGKNIGDIRKMMPNKKISILSSVRIGIQIIEALSLLHSKGWLH 165
Query: 195 RDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKS---LSGTARYMS 251
RD+KP N +G + V+L+DFGM++ +R+ RE ++ GT RY S
Sbjct: 166 RDLKPTNCCLGLDEK--RKTVYLVDFGMSRKFRNDNGS----LRESRTYCGFRGTTRYCS 219
Query: 252 INTHLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKAANNKLKYEKIGEKKRSTNVYDLS 311
H REQ DD+ L + + G LPW+ +++A+ +KI + + D+
Sbjct: 220 YRMHDRREQGPVDDLWCLYYSLGELIEGCLPWRDIESADEMAHVKKILKHE------DIF 273
Query: 312 QGLPVQFGRYLEIVRNLGFEETPDYEGYRKLLLSVLDELGQKLDGEYDWM 361
+P +F + +R L TPDY ++ +L + + + E+D M
Sbjct: 274 HSMPSKFASFGRNLRRLRPANTPDYTKFQNILAYCVKFVDDNAEFEWDVM 323
>CE28799 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 379
Score = 112 bits (280), Expect = 1e-24
Identities = 80/290 (27%), Positives = 141/290 (48%), Gaps = 12/290 (4%)
Query: 77 YKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPRKTDA-PQLKDEYRTYKILSGSEGIPQ 135
+K+ + I G F ++ + + N A+K E ++ ++ P LK + G G P
Sbjct: 26 WKVLRNIYSGPFSDVYVVADTVTNEKYAMKCERQEGNSRPVLKLDVMVLMATKGLRGFPN 85
Query: 136 AYYFGQEGLHNILVIDLLGPSLEDLFDWCG-RRFSIKTVVHVAIQMITLIEELHDHDLIY 194
G+ ++ ++ L+GP L L R+FS+ T + + Q + +E+LH+ +
Sbjct: 86 FVAAGRTDVYRYCIMQLVGPDLGRLRRTRPERKFSLPTALQILGQTLRRLEDLHNCGWLC 145
Query: 195 RDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTARYMSINT 254
RD+K NF IG + + V+++DFG A+ + D + K IP R +L GT +Y +++
Sbjct: 146 RDVKAPNFCIGVGE--NESTVYILDFGFARKFVDKEGKI-IPPRTAAALMGTFQYCAVSA 202
Query: 255 HLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKAANNKLKYEKIGEKKRSTNVYDLS--- 311
H ++Q RDD+E+ ++ L+G LPW + N +++IGE K + L
Sbjct: 203 HSHKDQCARDDLESWFYMGIELLKGPLPWANIDGHKN---HKQIGEAKVAIRSEPLRSEF 259
Query: 312 -QGLPVQFGRYLEIVRNLGFEETPDYEGYRKLLLSVLDELGQKLDGEYDW 360
+G+P QF L I+ + + P+Y+ LL E L DW
Sbjct: 260 FEGVPKQFNEILTILDQTSYFDRPNYKKLGDLLSQAATEHQVTLKEPLDW 309
>CE08640 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 307
Score = 111 bits (277), Expect = 3e-24
Identities = 79/294 (26%), Positives = 138/294 (46%), Gaps = 31/294 (10%)
Query: 77 YKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPRKTDAPQLKDEYR--TYKILSGSEGIP 134
Y +GKK+ +G +G ++E + + P A K E + + L +Y T G+E +
Sbjct: 36 YAVGKKVAQGRYGAVYEVLRRSDGKPFACKLEICEAHSHGLDQDYSVMTKAAKRGAENLV 95
Query: 135 QAYYFGQEGLH-NILVIDLLGPSLEDL-FDWCGRRFSIKTVVHVAIQMITLIEELHDHDL 192
+ G+ H +++ LLG +L +L F + RFS+ T + +A+ I I+ LH
Sbjct: 96 RMIDRGKIEEHFKFIIMPLLGENLMNLRFLFEDGRFSLSTGLRLALFAIQPIQSLHQLGY 155
Query: 193 IYRDIKPDNFLIGRPNQ----PDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTAR 248
++RDIK NF I P P+A + LID+G+ + ++D + P + K GT R
Sbjct: 156 VHRDIKASNFCIADPQMLHQNPEALKLCLIDYGICRSFKDKSGELKTPRTDIK-FRGTNR 214
Query: 249 YMSINTHLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKAANNKLKYEKIGEKKRSTNVY 308
Y S+ H G EQS +DDME+ ++ + G LPW + +K
Sbjct: 215 YASLAAHYGDEQSAKDDMESWFYMMIELISGNLPWSFMHRDQHK---------------- 258
Query: 309 DLSQGLPVQFGRYLEIVRNLGFEETPDYEGYRKLLLSVLDELGQKLDGEYDWMK 362
V+F R + L ++ T DY +++ + G +++ ++DW +
Sbjct: 259 ------EVEFHRIQAYLMGLKYQNTVDYTFISEMVQLAMRNNGVRMNEKFDWQE 306
>CE05253 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 380
Score = 111 bits (277), Expect = 3e-24
Identities = 82/292 (28%), Positives = 139/292 (47%), Gaps = 17/292 (5%)
Query: 77 YKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPRKTDAPQLKDEYRTYKIL--SGSEGIP 134
++I KK+GEG+FG +++ N ++ A+K E + LK E L +G
Sbjct: 16 WQIDKKLGEGAFGAVYKCSNPKGDL-FALKVEGKDEKIQLLKMEVYVLNELKKAGGRHFC 74
Query: 135 QAYYFGQEGLHNILVIDLLGPSLEDLFDWCG-RRFSIKTVVHVAIQMITLIEELHDHDLI 193
GQ N +V+ +G SL DL ++FS+ T + +A Q + +E++H+ +
Sbjct: 75 NIEDKGQVDNFNYVVMTFVGLSLADLRAISPTKKFSMGTAISIARQSLEALEDMHNIGYL 134
Query: 194 YRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTARYMSIN 253
+RD+KP N+ IGR + V+++DFGMA+ + P R GT +Y ++
Sbjct: 135 HRDVKPGNYTIGRAEVNELRKVYVLDFGMARKFAHEDGTIKKP-RNVAGFRGTVKYAPVS 193
Query: 254 THLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKAANNKLKYEKIGEKKRSTNVYDLSQ- 312
H GRE R+DD E ++ +G LPW+ N + + +G +KR+ + +
Sbjct: 194 CHAGRELCRQDDCETWLYMVVELTKGSLPWR------NMTEIQDVGNEKRAIRRDPIVKK 247
Query: 313 ----GLPVQFGRYLEIVRNLGFEETPDYEGYRKLLLSVLDELGQKLDGEYDW 360
G P ++ LE + F + P+YE LL + G + YDW
Sbjct: 248 KMFGGCPREYLDILEAIDKGQFFDEPNYERIYYLLREAMKNTG-STEYPYDW 298
>CE06632 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 305
Score = 110 bits (276), Expect = 4e-24
Identities = 84/299 (28%), Positives = 142/299 (47%), Gaps = 28/299 (9%)
Query: 77 YKIGKKIGEGSFGVLF-EGVNMINNVPVAIKFEPRKTDAPQLKDEY-------------R 122
+ I KK+GEG+FG ++ V A+K E LK E R
Sbjct: 19 WTILKKLGEGAFGAVYLVSQKEKPKVEYALKVEAESDPLGLLKMEVAVLLEVKKQKIVGR 78
Query: 123 TYKILSGSEGIPQAYYFGQEGLHNILVIDLLGPSLEDLFDWCG-RRFSIKTVVHVAIQMI 181
+ L+ +PQ + N +V+ L+G SL+DL +FS+ T + VA Q +
Sbjct: 79 HFLELADRGNLPQKF--------NYMVMTLVGKSLQDLRKTAPFNKFSMGTAISVARQSL 130
Query: 182 TLIEELHDHDLIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKK 241
+E+LH+ ++RDIKP N+ IGR + V+++DFGMA+ + P R +
Sbjct: 131 EAVEDLHNIGFLHRDIKPGNYTIGRKEMHELRKVYMLDFGMARKFAREDGTLRNP-RARA 189
Query: 242 SLSGTARYMSINTHLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKAANNKLKYEKIGEK 301
GT +Y + H+ REQ R+DD+E+ ++ G+LPW+ L +++ ++K +
Sbjct: 190 GFRGTVKYAPLACHIQREQCRKDDIESWLYMVVEMTCGRLPWRNLTESDDVGVFKK---E 246
Query: 302 KRSTNVYDLSQGLPVQFGRYLEIVRNLGFEETPDYEGYRKLLLSVLDELGQKLDGEYDW 360
++T + L G P +F I+ F + P+Y +LL + + + YDW
Sbjct: 247 CKTTRLRCLFGGCPREFTEVFPILDKGKFFDAPEYTTIYELLEKAMVNT-KSNEFPYDW 304
>CE05474 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 332
Score = 110 bits (274), Expect = 7e-24
Identities = 81/294 (27%), Positives = 139/294 (46%), Gaps = 16/294 (5%)
Query: 77 YKIGKKIGEGSFGVLFE---GVNMINNVPVAIKFEPRKTDAPQLKDEYRTYKILS--GSE 131
+ I KKI +G F ++ NM N A+K E ++ LK E + ++ GS
Sbjct: 34 WTIEKKIAQGDFNFIYMCNGSSNMSNYKQFALKCESAQSPLQMLKVEAFVLQTIAKRGSR 93
Query: 132 GIPQAYYFGQ-EGLHNILVIDLLGPSLEDLFDWC-GRRFSIKTVVHVAIQMITLIEELHD 189
G+ +G+H I V+ ++G +L D S+ + V IQ+I +E+LH+
Sbjct: 94 HFCDIEDIGKFQGIHYI-VMHMIGRALVDYMKTSMSGAISVNCALSVGIQLIEALEDLHN 152
Query: 190 HDLIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTARY 249
I+RD+KP N GR ++ + ++L+ FG+++ Y D K + P R+ GT RY
Sbjct: 153 CGFIHRDLKPSNICFGRKDRNELGKLYLLSFGISRRYLDSKNQMRKP-RDNVEFRGTVRY 211
Query: 250 MSINTHLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKAANNKLKYEKIGEKKRSTNVYD 309
S+N H +E +R+DD+E+ +V + GQLPW+GL + ++ ++ R +
Sbjct: 212 ASLNCHQLQELNRKDDLESAFYVIVEMITGQLPWKGLP---DGAAVARVKQQSRHPSAIA 268
Query: 310 LSQGLPVQFGRYLEI---VRNLGFEETPDYEGYRKLLLSVLDELGQKLDGEYDW 360
L P E+ + + + PDY +L + Q + YDW
Sbjct: 269 LFLRAPCPMEELREVMILIDSYNYFTAPDYVNICNILRRAMRRSPQP-EHPYDW 321
>CE06688 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 367
Score = 108 bits (270), Expect = 2e-23
Identities = 80/271 (29%), Positives = 130/271 (47%), Gaps = 14/271 (5%)
Query: 77 YKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPRKTDAPQLKDEYRTYKILSGSEGIPQA 136
YK+ +G+G +G ++ + + + AIK E A K Y +L G+ I
Sbjct: 24 YKVLALLGKGGYGAVYSVLRLSDMEKFAIKCE---NAAACRKALYMDCNVLKGAAKIQSR 80
Query: 137 YYF------GQEGLHNILVIDLLGPSLEDL-FDWCGRRFSIKTVVHVAIQMITLIEELHD 189
++ + N +V+ L+G +L DL D RF+ T + A Q + IEELH
Sbjct: 81 HFCTVIDQAAVKNRFNFIVMKLIGKNLWDLRMDTAECRFTKGTSLKAASQCLISIEELHR 140
Query: 190 HDLIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTARY 249
++RDIKP NF +GR + + + ++DFG+ + + + R K GT RY
Sbjct: 141 FGFLHRDIKPGNFAVGRKESNEHHTIFMLDFGLCREFVKRGEGRLRTQRAKSQFRGTTRY 200
Query: 250 MSINTHLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKAANNK--LKYEKIGEKKRSTNV 307
IN+ L + R+DD+E+ ++ + G LPW+ KA + LKY+K + +
Sbjct: 201 APINSMLEIDTGRKDDIESWLYMVAEWTSGGLPWRKFKATEREKVLKYKKDVRTDKEI-M 259
Query: 308 YDLSQGLPV-QFGRYLEIVRNLGFEETPDYE 337
DL P+ +F R L+ V L F PDY+
Sbjct: 260 ADLFYNCPLKEFERILKYVDELDFYSEPDYK 290
>7304307 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 936
Score = 107 bits (266), Expect = 6e-23
Identities = 91/341 (26%), Positives = 141/341 (40%), Gaps = 68/341 (19%)
Query: 72 IVGLHYKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPRKTDAPQLKDEYRTYKILSGSE 131
+V +K+ +KIG G FG ++EG ++I VA+K E + LK E K L G E
Sbjct: 262 VVKERWKVVRKIGGGGFGEIYEGQDLITREQVALKVESARQPKQVLKMEVAVLKKLQGKE 321
Query: 132 GIPQAYYFGQEGLHNILVIDLLGPSLEDLFDWCGRRFSIKTVVHVAIQMITLIEELHDHD 191
+ + F CGR V
Sbjct: 322 HVCR-------------------------FIGCGRNDRFNYV------------------ 338
Query: 192 LIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTARYMS 251
NF +GR + V+++DFG+A+ Y + P R GT RY S
Sbjct: 339 --------SNFSVGRLPY-NCRRVYMLDFGLARQYTTGTGEVRCP-RAAAGFRGTVRYAS 388
Query: 252 INTHLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKAANNKLKYEKIGEKKRSTNVYDLS 311
IN H RE R DD+ +L ++ F+ GQLPW+ +K E++G K + L
Sbjct: 389 INAHRNREMGRHDDLWSLFYMLVEFVNGQLPWRKIK------DKEQVGLTKEKYDHRILL 442
Query: 312 QGLPVQFGRYLEIVRNLGFEETPDYEGYRKLLLSVLDELGQKLDGEYDWMKLNGGRGWDL 371
+ LP ++LE +++L + + PDY L + G K YDW K++
Sbjct: 443 KHLPSDLKQFLEHIQSLTYGDRPDYAMLIGLFERCMKRRGVKESDPYDWEKVD-----ST 497
Query: 372 AINKKPNLHGYGHPTPPNEKSKRHRNKFNQVPLAVNNLNGS 412
AI N+ G+P+ P + H N Q+ +A +N +G+
Sbjct: 498 AIG---NISATGNPSIPIKSDYMHGN-ITQMTVAASNASGT 534
>CE04522 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 310
Score = 106 bits (264), Expect = 1e-22
Identities = 85/299 (28%), Positives = 146/299 (48%), Gaps = 27/299 (9%)
Query: 76 HYKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPRKTDAP-QLKDEYRTYKILSGSEGIP 134
+Y I K +GEG FG +++ + A+K E ++ P +LK E K++
Sbjct: 24 NYVIDKLLGEGGFGAVYKVKDSKTGNFYAMKVEKKQEKKPSKLKMEIMILKLVCNER--- 80
Query: 135 QAYYF---------GQEGLHNILVIDLLGPSLEDLFDWCGRRFSIKTVVHVAIQMITLIE 185
Q +F +EG LV++L G SL DL G+ F+ T + V+ Q + E
Sbjct: 81 QTSHFTKIIDRGKKDKEGFF-FLVMELAGSSLADLKRNRGKAFTCPTGLSVSQQCLEACE 139
Query: 186 ELHDHDLIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSG 245
+LH H I+RD+KP NF G ++ + ++++DFG+++ + + K P R G
Sbjct: 140 DLHKHGFIHRDLKPANFACGADDK--QHTIYILDFGISRRIINNQNKLKTP-RVTIRFKG 196
Query: 246 TARYMSINTHLGREQSRRDDMEALGHVFFYFLRGQLPWQGL--KAANNKLKYEKIGEKKR 303
T ++ S++ H G E +DD E+ +FY L + GL + AN+K K+ E+ R
Sbjct: 197 TLKFASLSCHKGIEMGWKDDCES----WFYMLLDLIVPFGLVWRGANDKDTVCKLKEEAR 252
Query: 304 STNVYDLSQGLP--VQFGRYLEIVRNLGFEETPDYEGYRKLLLSVLDELGQKLDGEYDW 360
++ QG+ V+ + + + L +++ DY+ K L+ D G +D YDW
Sbjct: 253 GKK--EMFQGIKCGVELNKIIVYIDKLQYQDHVDYQYIYKTLVDACDTCGGNMDAPYDW 309
>CE20743 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 540
Score = 105 bits (262), Expect = 2e-22
Identities = 77/247 (31%), Positives = 124/247 (50%), Gaps = 12/247 (4%)
Query: 77 YKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPRKTDAPQLKDEYRTYKILSGSEG---I 133
+ I +IGEG+F +F G ++ + A+K E R T + E ++LS I
Sbjct: 107 WMITHQIGEGTFAKIFVGRSLPFDQYYAVKIEVRLTSMDFIDHEVTVMRLLSYPNELPHI 166
Query: 134 PQAYYFGQEGLHNILVIDLLGPSLEDLFDWC-GRRFSIKTVVHVAIQMITLIEELHDHDL 192
P+ +F ++ N V+ LLG +L DL C RRF T + IQ++ ++ +H+
Sbjct: 167 PKCVFFSKQKDLNFFVMTLLGENLRDLKLKCPDRRFLRGTWSRLGIQILYALKLMHEKGF 226
Query: 193 IYRDIKPDNFLIG-RPNQPDANMVHLIDFGMAKLYRDPKTKQHI--PYREKKSLSGTARY 249
I+RDIKP+N L+G ++ + +VH+IDFG+ + + K K P R K G+ +
Sbjct: 227 IHRDIKPENLLMGAADDRKRSRIVHVIDFGLTRQWAWSKEKAFYARPLRTKVQFRGSLNF 286
Query: 250 MSINTHLGREQSRRDDMEALGHVFFYFLRGQLPWQGLK----AANNKLKYEKIGEKKRST 305
S N HLG + R+DD+ +L L +LPW G+K A K+ E K +
Sbjct: 287 TSSNAHLGYKLGRKDDLWSLLFT-LVDLNDRLPWHGVKDHMILARQKMNMEDTPTSKYTF 345
Query: 306 NVYDLSQ 312
+LS+
Sbjct: 346 EEVELSE 352
>CE02393 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 366
Score = 103 bits (256), Expect = 9e-22
Identities = 83/283 (29%), Positives = 137/283 (48%), Gaps = 14/283 (4%)
Query: 83 IGEGSFGVLFEGVNMINNVPVAIKFEP---RKTDAPQLKDEYRTYKILSGSEGIPQAYYF 139
IG+G +G ++ ++M VAIK EP + A ++ E L G +P +
Sbjct: 74 IGKGGYGEIYLAIDMKLAEEVAIKAEPLVRKGKIARRMILEQAVLVKLQGKPHVPWIFGS 133
Query: 140 GQEGLHNILVIDLLGPSLEDLFDWCG-RRFSIKTVVHVAIQMITLIEELHDHDLIYRDIK 198
G N +V+ LL +L D+ R+ S +V +A+Q I + +LHD ++RDIK
Sbjct: 134 GHTENFNFIVLQLLSANLGDIRRMSPTRKLSKSSVGRIAVQAIAALRDLHDVGYLHRDIK 193
Query: 199 PDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTARYMSINTHLGR 258
P N G ++ +++ L+DFG+ + Y+DP + +R K GT RY+S H
Sbjct: 194 PGNMCFGITSKT-RHVLMLLDFGLVRRYKDPDGEWRT-HRVKAGFRGTQRYVSTRVHRRL 251
Query: 259 EQSRRDDMEALGHVFFYFLRGQLPWQGLKAANNKLKYEKIGEKKRSTNVYDLSQGLPVQF 318
EQ+ DDM +L + L G+LPW+ ++ ++ K + + + ++ SQ L ++F
Sbjct: 252 EQTPTDDMVSLLYTLIELLAGELPWRNIENSDAIWKMKDELHHGQIDHFHESSQEL-IEF 310
Query: 319 GRYLEIVRNLGFEETPDYEGYRKLLLSVLD-ELGQKLDGEYDW 360
+ + R E P Y L SV L +KL YDW
Sbjct: 311 SQL--VSRLDPMSELP----YTTLQASVKKLYLPKKLSDPYDW 347
>CE02142 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 471
Score = 102 bits (255), Expect = 1e-21
Identities = 81/295 (27%), Positives = 131/295 (43%), Gaps = 14/295 (4%)
Query: 72 IVGLHYKIGKKIGEGSFGVLFEGVNMIN-NVPVAIKFEPRKTDAPQLKDEYRTYKILSGS 130
I+ + + IG+G++GV++E V + N A K E D LK E+ +L +
Sbjct: 21 IINGQFMAVQMIGKGAYGVVYEVVRRNSPNTRFACKAE-LAIDHNNLKTEWDLMTLLKDN 79
Query: 131 EGIPQ--AYYFGQEGLHNILVIDLLGPSLEDLFDWC-GRRFSIKTVVHVAIQMITLIEEL 187
+ G E N +V+ L+GPSL DL + F++ T AIQ + E+
Sbjct: 80 KSKHNIIGVELGSERNFNYIVMHLVGPSLSDLRKTVPNKTFTLFTTAVCAIQCFDSLVEI 139
Query: 188 HDHDLIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTA 247
I+RD+KP NF IG + +V+++DFG+ + + + + P R K GT
Sbjct: 140 QRIGYIHRDVKPSNFAIGVLGSEEEKLVYVLDFGLCRNMFNKQKELRKP-RMKAPFRGTI 198
Query: 248 RYMSINTHLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKAANNKLKYEKIGEKKRSTNV 307
Y S+N H E R DD +L ++ F LPW+ + + K K + T +
Sbjct: 199 LYCSLNIHQRMEPGRHDDFWSLLYMMIEFHLSDLPWENMSKEDTK--------KAKETKL 250
Query: 308 YDLSQGLPVQFGRYLEIVRNLGFEETPDYEGYRKLLLSVLDELGQKLDGEYDWMK 362
L P +F + L + + PDY R++L ++ D DW K
Sbjct: 251 DGLLARCPPEFRMIRCYLLTLTYSKEPDYVKLREVLCQIMTSKKFTPDMPLDWQK 305
>CE14744 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 429
Score = 102 bits (254), Expect = 1e-21
Identities = 80/295 (27%), Positives = 141/295 (47%), Gaps = 25/295 (8%)
Query: 81 KKIGEGSFGVLFEGVNMINNVPVAIKFEPRKTDAPQLKDEYRTYKILSGSEGIPQAYYFG 140
+++G G+FG ++ N A+K E LK E +I+ + P A +
Sbjct: 27 RELGRGAFGTVYHVSNKSTKQEAALKIEKMTAGDNLLKFER---EIMVAMQHEPTAIHIY 83
Query: 141 QEGLHN---ILVIDLLGPSLEDLFDWCGRRFSIKTVVHVAIQMITLIEELHDHDLIYRDI 197
+G++ +V+ L GP L+ + + F+ T++ V I+ + I+ +H++ I+RD+
Sbjct: 84 DDGIYKDYRYIVMTLCGPDLQKIAELMNNNFNQDTIIRVCIRTLLAIKTMHEYTYIHRDL 143
Query: 198 KPDNFLIGRPNQPDANMVHLIDFGMAKLY--RDPKTKQHIPY-REKKSLSGTARYMSINT 254
KP NF + P++ V+L D+GMA+ Y +D K + R GT RY S+N
Sbjct: 144 KPCNFAV--DFNPNSLHVYLFDYGMARKYATKDSGNKWQLRRPRNPAQFRGTVRYCSLNM 201
Query: 255 HLGREQSRRDDMEALGHVFFYFLR---GQLPWQGLKAANNKLKYEKIGEKKRSTNVYDLS 311
H +E SR DD+ + +F+ L LPW ++N + E + K+ N Y
Sbjct: 202 HKRKELSRVDDLWS----WFFMLMEMYAPLPW---TSSNIPERIEAL--KEDHLNEYLSK 252
Query: 312 QGLPVQFGRYLEIVRNLGFEETPDYEGYRKLLLSVLDELGQKLDG--EYDWMKLN 364
F +E + ++ + + PDY +L + L E+ KL G +YD ++N
Sbjct: 253 DSFLSSFLPLVEYLNSVQYADRPDYMKIYDILYAKLTEINGKLSGPMKYDVARIN 307
>CE01982 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 752
Score = 102 bits (254), Expect = 1e-21
Identities = 70/218 (32%), Positives = 115/218 (52%), Gaps = 11/218 (5%)
Query: 148 LVIDLLGPSLEDLF-DWCGRRFSIKTVVHVAIQMITLIEELHDHDLIYRDIKPDNFLIGR 206
+V+ L+GPSLED+ + FS T +VAIQ +T +++LH ++RDIKP N+ +G
Sbjct: 517 VVMGLVGPSLEDIRRKYLLGSFSKHTSFNVAIQTVTALQDLHSIGYLHRDIKPANYAVGL 576
Query: 207 PNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTARYMSINTHLGREQSRRDDM 266
++ D V+++DFG+AKLY D + +H R+K GT RY + +EQ R+DD+
Sbjct: 577 EDREDT--VYMLDFGIAKLYVD-ENGEHKVKRKKVKFLGTLRYACRACMMQQEQGRKDDL 633
Query: 267 EALGHVFFYFLRGQ--LPWQGLKAANNKLKYEKIGEKKRSTNVYDLSQGLPV-QFGRYLE 323
E ++ F + +PW+ L + LK + + TN S + + +
Sbjct: 634 ETWIYLVFDLMDESHGMPWRSLCSPKEILK----SKNEFFTNFDSSSVSATLKRLKGLVS 689
Query: 324 IVRNLGFEETPDYEGYRKLLLSVLDELGQKLDGEYDWM 361
V N+ +E TPDY+ L + E G K+ + DW+
Sbjct: 690 YVDNMQYETTPDYDYIINFLKTTATEAGAKISKKLDWI 727
Score = 57.8 bits (138), Expect = 4e-08
Identities = 49/217 (22%), Positives = 96/217 (43%), Gaps = 12/217 (5%)
Query: 148 LVIDLLGPSLEDLFD-WCGRRFSIKTVVHVAIQMITLIEELHDHDLIYRDIKPDNFLIGR 206
LV+ G +L+++ S+ V +QM+ I+ LH ++R+I P F G
Sbjct: 181 LVVSSYGSTLQEILKKTINGPLSMDCSFVVGLQMLRAIQNLHSLGYVHRNINPSAFNCGL 240
Query: 207 PNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTARYMSINTHLGREQSRRDDM 266
D ++L DF + + + K+H+ R + G R+ + ++Q R+DD+
Sbjct: 241 GM--DETSLYLQDFRQVRKFEE--NKKHVTARSTVKMFGCGRFANRACQNSKDQGRKDDL 296
Query: 267 EALGHVFFYFL-RGQLPWQGLKAANNKLKYEKIGEKKRSTNVYDLSQGLPVQFGRYLEIV 325
E+ + FY + G L W+ A++++ ++ S+ P L V
Sbjct: 297 ESWIYTLFYLIDHGSLSWK--NEADSQIVVQQKDLFMTGDGKEQFSRA-PRGLAPLLSKV 353
Query: 326 RNLGFEETPDYEGYRKLLLSVLDELGQKLDGE-YDWM 361
F P+Y+ ++ L+ + + QKL+ + DW+
Sbjct: 354 NGYEFTSAPEYDSFKNLINGI--QTSQKLNKKSCDWL 388
>CE03754 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 366
Score = 101 bits (252), Expect = 2e-21
Identities = 82/300 (27%), Positives = 141/300 (46%), Gaps = 20/300 (6%)
Query: 77 YKIGKKIGEGSFGVLFEGVNMINNVPVA-IKFEPRKTDAPQ-LKDEYRTYKILSGSEGIP 134
+KIGK I EG FG ++ ++ + VA +K E + + +K E L+ + +P
Sbjct: 24 WKIGKTIDEGGFGKVYIATSISDPKKVAALKAESNEIEGGSAIKLEAMILNKLNANGPVP 83
Query: 135 Q---AYYFGQEGLHNILVIDLLGPSLEDLFDW---CGRRFSIKTVVHVAIQMITLIEELH 188
+ + L+ +V+ LLG +L L FS T + IQ + ++ +H
Sbjct: 84 HIPVVHLCAKRKLYCYMVMTLLGRNLRKLKSTNLVVNNGFSRGTWSRIGIQCLYALKYVH 143
Query: 189 DHDLIYRDIKPDNFLIGRPNQPD-ANMVHLIDFGMAKLYR--DPKTKQHIPYREK--KSL 243
D+ I+RD+KP NFL+G + A +VH++DFG+A+ + + + I R +
Sbjct: 144 DNGFIHRDVKPQNFLLGNETDSERARIVHILDFGLARPFAVFHARENKWIARRARGTAEF 203
Query: 244 SGTARYMSINTHLGREQSRRDDMEALGHVFFYFLRGQ-LPWQGLKAANNKLKYEKIGEKK 302
GT RY S N HL +EQ R DD+ +L +V G+ LPWQ + E++ + K
Sbjct: 204 RGTLRYTSPNVHLRKEQGRVDDVWSLLYVIIELNGGKALPWQ------TDSQRERVEQMK 257
Query: 303 RSTNVYDLSQGLPVQFGRYLEIVRNLGFEETPDYEGYRKLLLSVLDELGQKLDGEYDWMK 362
+ + +P + + + +L + + PDY K V++ +YDW K
Sbjct: 258 LNLPAKVVMSNMPACMDKVMPHLASLDYYQRPDYHMIFKCFWQVMENEKITPSSKYDWEK 317
>CE19439 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 330
Score = 100 bits (250), Expect = 4e-21
Identities = 80/295 (27%), Positives = 141/295 (47%), Gaps = 18/295 (6%)
Query: 77 YKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPRKTDA---PQLKDEYRTYKILSGSEGI 133
Y + + +GEG FG ++ A+K E +K D +LK E K++ +
Sbjct: 24 YTVVRLLGEGGFGAVYLVEQAKTKKQFAMKVE-KKMDTRKHSKLKMEIAILKLVGTCKHF 82
Query: 134 PQAYYFGQEGLHN--ILVIDLLGPSLEDLF-DWCGRRFSIKTVVHVAIQMITLIEELHDH 190
+ G++ +V+ L+G SL L + + F+ T + V Q + +EELH
Sbjct: 83 TKIEDRGKKDKEGYFFIVMQLVGKSLSGLKKERPNQIFTFGTGMGVGSQCLEAVEELHKQ 142
Query: 191 DLIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSL--SGTAR 248
I+RD+KP N+ G+ + + ++++++DFG+A+ Y + K + P RE + SGT R
Sbjct: 143 GFIHRDLKPQNYASGQDD--ERHLIYILDFGIARKYLNDKKEMKTP-RESVAFKASGTIR 199
Query: 249 YMSINTHLGREQSRRDDMEALGHVFF-YFLRGQLPWQGLKAANNKLKYEKIGEKKRSTNV 307
+ ++ H E +DD E+ ++ L G LPW+ K N L KI E R N
Sbjct: 200 FAPLSCHRYTEMGPKDDCESWFYLLIDLILEGGLPWRHCKVKNEVL---KIKENTRKDNR 256
Query: 308 YDLSQGLP--VQFGRYLEIVRNLGFEETPDYEGYRKLLLSVLDELGQKLDGEYDW 360
L +G+P + + L+ + + +++ DY+ K L G ++ YDW
Sbjct: 257 AALYKGIPQTSELNKILDYIDSRAYQDRIDYKFIYKALGEACSNAGCDINAPYDW 311
>CE18539 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 327
Score = 100 bits (250), Expect = 4e-21
Identities = 83/296 (28%), Positives = 137/296 (46%), Gaps = 20/296 (6%)
Query: 76 HYKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPR--KTDAPQLKDEYRTYKILSGSEGI 133
+Y + + +GEG FG ++ + + A+K E + K +LK E K++ +
Sbjct: 23 NYTVVRLLGEGGFGAVYLVQDNKSKKQSAMKVERKIEKRKHSKLKMEIAILKLVGSGKHF 82
Query: 134 PQAYYFGQEGLHNI--LVIDLLGPSLEDL-FDWCGRRFSIKTVVHVAIQMITLIEELHDH 190
Q G++ LV++L+G SL DL D + FS T + V+ Q + +EELH
Sbjct: 83 TQIVDRGKKDKEGFFFLVMELVGKSLADLKADRPDKVFSFATGLGVSCQCLEAVEELHKT 142
Query: 191 DLIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTARYM 250
I+RD+KP N+ G + + ++++DFG+A+ Y + K + P RE GT R+
Sbjct: 143 GFIHRDLKPQNYACGLDEK--RHNIYILDFGIARKYLNTKNELKTP-RETVGFKGTVRFA 199
Query: 251 SINTHLGREQSRRDDMEALGHVFFYFL-----RGQLPWQGLKAANNKLK-YEKIGEKKRS 304
I H E +DD E+ +FY L LPW+ L + LK E+ + KRS
Sbjct: 200 PIACHRNTEMGPKDDCES----WFYLLLDLIVPSGLPWRKLSDKHEVLKEKEECRKDKRS 255
Query: 305 TNVYDLSQGLPVQFGRYLEIVRNLGFEETPDYEGYRKLLLSVLDELGQKLDGEYDW 360
+ L Q + L+ + +++ DY+ K L +D YDW
Sbjct: 256 SLFAGLRQ--TDYLSKVLDYIDGRAYQDRVDYQFIYKNLAEACKVCNLDIDSPYDW 309
>CE15320 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 368
Score = 100 bits (249), Expect = 6e-21
Identities = 82/299 (27%), Positives = 136/299 (45%), Gaps = 27/299 (9%)
Query: 72 IVGLHYKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPRKTDAPQLKDEYRTYKILSGSE 131
++ +++ IG G F +++ + + AIK E D ++K E L GS
Sbjct: 64 VISGRFEVKGIIGGGGFAQIYKAWDKVRKEDCAIKVEHESQDIRRMKLEITVLLALRGSM 123
Query: 132 GIPQAYYFG----QEGLHNILVIDLLGPSLEDLFDWCG-RRFSIKTVVHVAIQMITLIEE 186
GIP+ G ++ + +V+ L+G +L D+ +R + +T+ IQ++ +
Sbjct: 124 GIPEILAQGKWQHEDNKSHYIVMQLVGRNLSDVRRALPHKRITERTLYRAMIQVLKALSL 183
Query: 187 LHDHDLIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGT 246
+H ++RD+KP N IG D ++LID+G+ + Y D P R L GT
Sbjct: 184 VHGAGFLHRDLKPSNCCIGAI---DCTRIYLIDYGLTRQYLDKGGIVRKP-RAGVGLRGT 239
Query: 247 ARYMSINTHLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKAANN--KLKYEKIGEKKRS 304
RYMS++ H ++ ++D+ A + G LPW K N KLK IG+K
Sbjct: 240 VRYMSLDAHARQDLGPKNDLVAFLYTTIECGDGYLPWSHEKTHENIIKLKQAHIGDK--- 296
Query: 305 TNVYDLSQGLPVQFGRYLEIVRNLGFEETPDYEGYRKLLLSVLDELGQ---KLDGEYDW 360
L PV + E + +L + PDYE LL++++E K YDW
Sbjct: 297 -----LCTKQPV-MTKAAEYIESLNYHSIPDYE----KLLALMEECNPPDLKESEPYDW 345
>CE06796 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 359
Score = 100 bits (249), Expect = 6e-21
Identities = 78/290 (26%), Positives = 135/290 (45%), Gaps = 14/290 (4%)
Query: 77 YKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPR-KTDAPQLKDEYRTYKILSGSEGIPQ 135
YK+ I G F +F + + +P A+K E + K P LK ++ + L G P
Sbjct: 29 YKMCDSIATGPFSSVF--LVEKDGIPYAMKVESQSKCLRPVLKLDHAVLRALGHQSGFPS 86
Query: 136 AYYFGQEGLHNILVIDLLGPSLEDLFDWCGR-RFSIKTVVHVAIQMITLIEELHDHDLIY 194
G+ +V+ L+GP L L ++ + RF+ TV +A+Q + + LH+ +
Sbjct: 87 LTSAGRTENFKYVVMQLVGPDLSMLLEFAPQQRFTSSTVYKIALQTLDRLRVLHEAGWLN 146
Query: 195 RDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTARYMSINT 254
RD+K NF +G ++++V+++DFG+ + Y + + + R GT Y + +
Sbjct: 147 RDVKAQNFAVGLGE--ESSIVYMLDFGLTRKYLEHNGSRSL-LRPHGPSVGTFPYAPLAS 203
Query: 255 HLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKAANNKLKYEKIGEKK----RSTNVYDL 310
+QS DD+E ++ + L+G LPW K A L K+ E K R + L
Sbjct: 204 LGFCDQSPIDDIEGWLYMIVHLLKGGLPWHNSKRA---LNLPKVREWKMYCRRPGGKHYL 260
Query: 311 SQGLPVQFGRYLEIVRNLGFEETPDYEGYRKLLLSVLDELGQKLDGEYDW 360
G+P + +++ N ETPDY ++LS+ L +DW
Sbjct: 261 FAGIPKGWADIFDVIVNTAPHETPDYNKIANMVLSIARNELIDLTAPFDW 310
>CE15237 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 350
Score = 99.0 bits (245), Expect = 2e-20
Identities = 81/286 (28%), Positives = 131/286 (45%), Gaps = 21/286 (7%)
Query: 83 IGEGSFGVLFEGVN-------MINNVPVAIKFEPRKTDAPQLKDEYRTYKILSGSEGIPQ 135
IG G FG ++ G + +I PV +K PR+ + K YR L G +P
Sbjct: 54 IGRGGFGQIYYGSDATFPEDVVIKIEPVVLKGRPRRRMILEQKVLYR----LQGRPHVPI 109
Query: 136 AYYFGQEGLHNILVIDLLGPSLEDLFDWCG-RRFSIKTVVHVAIQMITLIEELHDHDLIY 194
G N +V+ LLGP++ DL +R S TV + IQ I + ++H I+
Sbjct: 110 MCASGHTEQLNFIVMQLLGPNIGDLKKRSPVKRLSQTTVARIMIQGIAALRDVHSLGYIH 169
Query: 195 RDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTARYMSINT 254
RD+KP N G Q +++ L+D+GM + +++ + R K GT RY S+
Sbjct: 170 RDVKPANMCFG-VTQSTRHVLKLVDYGMVRRFKNVDGTRR-KQRYKPGFRGTLRYSSVRV 227
Query: 255 HLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKAANNKLKYEKIGEKKRSTNVYDLSQGL 314
H G+EQ+ DD ++ + L LPW+ + + ++ K+ + + Y L G
Sbjct: 228 HDGKEQTPVDDFVSMAYSGAELLLVNLPWK--LVSTDDIRQTKV-DFNTPNSPYLLLTG- 283
Query: 315 PVQFGRYLEIVRNLGFEETPDYEGYRKLLLSVLDELGQKLDGEYDW 360
F + + NL E+ PD+ + LL + G+ L YDW
Sbjct: 284 -PYFSVFCGAIFNLRSEDEPDHSSLQNLLCDM--TRGKSLREAYDW 326
>CE13469 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 342
Score = 99.0 bits (245), Expect = 2e-20
Identities = 76/287 (26%), Positives = 121/287 (41%), Gaps = 49/287 (17%)
Query: 74 GLHYKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPRKTDAPQLKDEYRTYKILSGSEGI 133
G YK+G +G+G +G +F ++ +++ +A+K E K QLK E K + +G
Sbjct: 58 GKKYKLGPVLGDGGYGTVF--LSQDDDIKIAVKTE--KFSKSQLKIEIVVLK--AAMQG- 110
Query: 134 PQAYYFGQEGLHNILVIDLLGPSLEDLFDWCGRRFSIKTVVHVAIQMITLIEELHDHDLI 193
H + EELH +
Sbjct: 111 --------------------------------------NCKHFCELVDCACEELHRIGFV 132
Query: 194 YRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTARYMSIN 253
RD+KP NF G + + + + DFG+A+ Y D K Q IP R++ GT RY S+N
Sbjct: 133 SRDVKPGNFAPGVKSNRQSRTIFMYDFGLARKYID-KNNQVIPTRKEVGWRGTTRYGSLN 191
Query: 254 THLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKAANNKLKYEKIGEKKRSTNVYDLSQG 313
H + RRDD+E+ + RG LPW+ + ++ ++ E R+T
Sbjct: 192 AHKRLDLGRRDDLESWFYGLVEMTRGTLPWRNVV---DRSSVQRAKEASRNTGRTQFLFE 248
Query: 314 LPVQFGRYLEIVRNLGFEETPDYEGYRKLLLSVLDELGQKLDGEYDW 360
P Q+ + IV + FE PDY+ KLL+ +E + +DW
Sbjct: 249 TPSQYDKIFTIVDSYAFESAPDYKQINKLLVEAREERQLRDREHWDW 295
>CE12108 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 308
Score = 99.0 bits (245), Expect = 2e-20
Identities = 84/295 (28%), Positives = 137/295 (45%), Gaps = 23/295 (7%)
Query: 77 YKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPRKTDAPQLKDEYRTYKILS--GSEGIP 134
+ + KK+GEG+FG ++ V A+K E P LK E + LS G + +
Sbjct: 19 FTVFKKLGEGTFGAVY-AVRDDAGAEHALKAELATEKIPLLKLELYVMQKLSMKGPKHMA 77
Query: 135 QAYYFGQEGLHNILVIDLLGPSLEDLFDWC-GRRFSIKTVVHVAIQMITLIEELHDHDLI 193
G+ N +V+ LG SL+D ++ + + +IQ + +EELH +
Sbjct: 78 TLIDKGRHENFNYIVMKFLGKSLQDAKKTGPDGHLTLGSAIGASIQCLEALEELHWCGFL 137
Query: 194 YRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTARYMSIN 253
+RD+KP NF +GR + + ++DFG+ + + D + P R K GT RY I
Sbjct: 138 HRDVKPGNFCLGRAELGELRKIFVLDFGLCRKFVDDRNVMLQP-RRKAPYRGTPRYAPIA 196
Query: 254 THLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKAANNKLKYEKIGEKKRSTN----VYD 309
+H E R+DD+E+ ++ F LPW K N + ++GE K+++ V
Sbjct: 197 SHNRAEHGRKDDVESWFYMLVDFTNAALPW---KVVN---EIPQVGEMKKNSRFDPLVTQ 250
Query: 310 LSQGLPV-QFGRYLEIVRNLGFEETPDYEGYRKLLLSVLDELGQKLDGE---YDW 360
L G PV ++ + + L F P+Y L+ S L L Q + + YDW
Sbjct: 251 LLAGCPVDEYRLIMNHIDGLSFFMEPNY----GLIYSTLKRLMQTRNIQEFPYDW 301
>Hs5454164 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 508
Score = 98.6 bits (244), Expect = 2e-20
Identities = 85/296 (28%), Positives = 143/296 (47%), Gaps = 34/296 (11%)
Query: 74 GLHYKIGKKIGEGSFGVLFEGVNMINNVP-------VAIKFEPRKTDAPQLKDEYRTYK- 125
G + +GKKIG G FG+++ + N P V ++++ +LK R K
Sbjct: 26 GNQWVLGKKIGSGGFGLIY--LAFPTNKPEKDARHVVKVEYQENGPLFSELKFYQRVAKK 83
Query: 126 --ILSGSE-------GIPQAYYFGQEGL----HNILVIDLLGPSLEDLFDWCGRRFSIKT 172
I E GIP Y G + +V++ LG L+ + G F T
Sbjct: 84 DCIKKWIERKQLDYLGIPLFYGSGLTEFKGRSYRFMVMERLGIDLQKISGQNGT-FKKST 142
Query: 173 VVHVAIQMITLIEELHDHDLIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTK 232
V+ + I+M+ ++E +H+++ ++ D+K N L+G N PD V+L D+G++ YR
Sbjct: 143 VLQLGIRMLDVLEYIHENEYVHGDVKAANLLLGYKN-PD--QVYLADYGLS--YRYCPNG 197
Query: 233 QHIPYRE--KKSLSGTARYMSINTHLGREQSRRDDMEALGHVFFYFLRGQLPW-QGLK-- 287
H Y+E +K +GT + S++ H G SRR D+E LG+ +L G+LPW Q LK
Sbjct: 198 NHKQYQENPRKGHNGTIEFTSLDAHKGVALSRRSDVEILGYCMLRWLCGKLPWEQNLKDP 257
Query: 288 AANNKLKYEKIGEKKRSTNVYDLSQGLPVQFGRYLEIVRNLGFEETPDYEGYRKLL 343
A K + E +S + S + ++L +L ++E P+Y+ +K+L
Sbjct: 258 VAVQTAKTNLLDELPQSVLKWAPSGSSCCEIAQFLVCAHSLAYDEKPNYQALKKIL 313
>CE27672 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 406
Score = 97.4 bits (241), Expect = 5e-20
Identities = 75/291 (25%), Positives = 135/291 (45%), Gaps = 12/291 (4%)
Query: 74 GLHYKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPRKTDAPQLKDEYRTYKILSGSEGI 133
G + + +K+G+G+ G +F +++ VAIK E T L E + + G+
Sbjct: 85 GDRFILRQKLGDGAMGHVF--LSIFGGRSVAIKAEKYSTG--MLPMEIKVLLSIRRHNGV 140
Query: 134 PQAYYFGQEGL---HNILVIDLLGPSLEDL-FDWCGRRFSIKTVVHVAIQMITLIEELHD 189
+ +N ++I +LG L L + R F++ T +A++ I IEELH+
Sbjct: 141 HFCDIIDYGTIRREYNYMIISILGKDLYRLRAEQPTRSFTLNTTTKIALETIEAIEELHN 200
Query: 190 HDLIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTARY 249
+ RD+KP NF G+ + + + DFG+AK + D K+ + R + GT RY
Sbjct: 201 IGYLSRDVKPSNFAPGQRDNGQHKTIFMFDFGLAKKFIDRDNKK-LKSRGEVGWRGTVRY 259
Query: 250 MSINTHLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKAANNKLKYEKIGEKKRSTNVYD 309
S+ H + RRDD+E ++ L G+LPW+ + + + K+ + S ++
Sbjct: 260 GSLQAHKRMDLGRRDDVECWFYMLIEMLVGELPWRHM-SDRTLVGQSKLSIRNESRRLF- 317
Query: 310 LSQGLPVQFGRYLEIVRNLGFEETPDYEGYRKLLLSVLDELGQKLDGEYDW 360
P QF ++++ FE P+Y + L+ + E ++DW
Sbjct: 318 -FNRTPRQFETIMDMIDGYSFEIRPEYRHLKALINEIRMENMIPDRCKWDW 367
>CE09980 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 380
Score = 97.4 bits (241), Expect = 5e-20
Identities = 71/271 (26%), Positives = 131/271 (48%), Gaps = 13/271 (4%)
Query: 77 YKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPRKTDAPQLKDEYRTYKILSGSEGIPQA 136
YK+ +G+G +G ++ + + + AIK E L + ++ G+ I
Sbjct: 24 YKVIALLGKGGYGAVYSVLRLSDMEKFAIKCEKATAGKKVLLMDCN---VMKGATQIKSR 80
Query: 137 YYF------GQEGLHNILVIDLLGPSLEDLFDWCGR-RFSIKTVVHVAIQMITLIEELHD 189
++ + N +V+ L+G +L DL G +F++ T + A Q + IE LH
Sbjct: 81 HFCTVLDRANVKDRFNFIVMKLIGKNLWDLRQDRGDGKFTMGTSLKAASQCLVSIEHLHS 140
Query: 190 HDLIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLY-RDPKTKQHIPYREKKSLSGTAR 248
++RDIKP NF GR + +++ ++DFG+ + Y + + K R GT R
Sbjct: 141 FGYLHRDIKPGNFAAGRKESNEHHVIFMLDFGLCREYVKRAEGKDLRAARTTAPFRGTTR 200
Query: 249 YMSINTHLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKAANNKLKYEKIGEKKRSTNVY 308
Y + + L ++QSR+DD+E+ ++ + G LPW+ LKA + + + + + ++
Sbjct: 201 YAPLASMLQQDQSRKDDIESWLYMVVEWTSGGLPWRKLKAHDREKVLQYKQDLRTKPDIL 260
Query: 309 D--LSQGLPVQFGRYLEIVRNLGFEETPDYE 337
D L +F R L+ + LG+ PDY+
Sbjct: 261 DDFLFLCPKKEFTRILKYLDTLGYYAVPDYK 291
>CE07450 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 380
Score = 97.4 bits (241), Expect = 5e-20
Identities = 71/271 (26%), Positives = 131/271 (48%), Gaps = 13/271 (4%)
Query: 77 YKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPRKTDAPQLKDEYRTYKILSGSEGIPQA 136
YK+ +G+G +G ++ + + + AIK E L + ++ G+ I
Sbjct: 24 YKVIALLGKGGYGAVYSVLRLSDMEKFAIKCEKATAGKKVLLMDCN---VMKGATQIKSR 80
Query: 137 YYF------GQEGLHNILVIDLLGPSLEDLFDWCGR-RFSIKTVVHVAIQMITLIEELHD 189
++ + N +V+ L+G +L DL G +F++ T + A Q + IE LH
Sbjct: 81 HFSTVLDRANVKDRFNFIVMKLIGKNLWDLRQDRGDGKFTMGTSLKAASQCLVSIEHLHS 140
Query: 190 HDLIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLY-RDPKTKQHIPYREKKSLSGTAR 248
++RDIKP NF GR + +++ ++DFG+ + Y + + K R GT R
Sbjct: 141 FGYLHRDIKPGNFAAGRKESNEHHVIFMLDFGLCREYVKRAEGKDLRAARTTAPFRGTTR 200
Query: 249 YMSINTHLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKAANNKLKYEKIGEKKRSTNVY 308
Y + + L ++QSR+DD+E+ ++ + G LPW+ LKA + + + + + ++
Sbjct: 201 YAPLASMLQQDQSRKDDIESWLYMVVEWTSGGLPWRKLKAHDREKVLQYKQDLRTKPDIL 260
Query: 309 D--LSQGLPVQFGRYLEIVRNLGFEETPDYE 337
D L +F R L+ + LG+ PDY+
Sbjct: 261 DDFLFLCPKKEFTRILKYLDTLGYYAVPDYK 291
>CE05212 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 373
Score = 97.4 bits (241), Expect = 5e-20
Identities = 87/294 (29%), Positives = 132/294 (44%), Gaps = 18/294 (6%)
Query: 77 YKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPRKTDAPQ-LKDEYRTYKILSGSEGI-- 133
Y I K + EG FG ++ V + A+K E + +K E + L+ E +
Sbjct: 27 YTIEKSLDEGGFGQVYL-VRDNSGKRFALKAESNDMEGGSAIKLEALILRKLNDGESVIH 85
Query: 134 -PQAYYFGQEGLHNILVIDLLGPSLEDLFDWCGR-RFSIKTVVHVAIQMITLIEELHDHD 191
P+ G+ + +V+ LLG +L+ L + + RF+ T + IQ + ++ +HD
Sbjct: 86 VPKLLLSGKRKKYCYMVMTLLGKNLKCLKNKRPKERFTRGTWSRIGIQCLYGLKYMHDCG 145
Query: 192 LIYRDIKPDNFLIGRPNQPD-ANMVHLIDFGM----AKLYRDPKTKQHIPYREKKSLSGT 246
++RDIKP NF++G + + A +VH++DFG+ AK KT R GT
Sbjct: 146 FVHRDIKPQNFMMGNEDDKERARIVHILDFGLARSFAKFSESSKTWSARRARGTAEFRGT 205
Query: 247 ARYMSINTHLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKAANNKLKYEKIGEKKRSTN 306
RY S N H +EQ R DD+ +L V L G LPWQ N K E++ K
Sbjct: 206 LRYTSPNVHFRKEQGRVDDIWSLLFVLIE-LNGGLPWQ------NVQKREEVEAMKMIMT 258
Query: 307 VYDLSQGLPVQFGRYLEIVRNLGFEETPDYEGYRKLLLSVLDELGQKLDGEYDW 360
D+ +P + R L PDY K L V+ GQ +DW
Sbjct: 259 DQDVMLNMPPCMCDIIPHFRTLDCYMRPDYLLVFKALWQVMLNEGQTTSSRFDW 312
>CE04892 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 758
Score = 95.5 bits (236), Expect = 2e-19
Identities = 67/221 (30%), Positives = 114/221 (51%), Gaps = 17/221 (7%)
Query: 148 LVIDLLGPSLEDLF-DWCGRRFSIKTVVHVAIQMITLIEELHDHDLIYRDIKPDNFLIGR 206
+V+ L+GPSLED+ + FS T +VAIQ +T + +LH ++RDIKP N+ +G
Sbjct: 523 VVMGLVGPSLEDIRRKYLLASFSKHTSFNVAIQTVTALRDLHSLGYLHRDIKPANYAVGL 582
Query: 207 PNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTARYMSINTHLGREQSRRDDM 266
+ D V+++DFG+AKLY D + H R+K GT RY + +EQ R+DD+
Sbjct: 583 DEREDT--VYMLDFGIAKLYVD-ENGVHKIKRKKVKFLGTLRYACRACMMQQEQGRKDDL 639
Query: 267 EALGHVFFYFL--RGQLPWQGL----KAANNKLKYEKIGEKKRSTNVYDLSQGLPVQFGR 320
E ++ F + +PW+ L + +K + + + +N+ + L V
Sbjct: 640 ETWIYLVFDLMDEAHGMPWRALCDPREILKSKNTFFATFDNFQFSNILKRLKDLVV---- 695
Query: 321 YLEIVRNLGFEETPDYEGYRKLLLSVLDELGQKLDGEYDWM 361
V ++ ++ TPDY L + +++G K+ + DWM
Sbjct: 696 ---YVDDMQYDTTPDYSYILNFLKTTANDVGAKITKKLDWM 733
Score = 66.6 bits (161), Expect = 9e-11
Identities = 51/189 (26%), Positives = 83/189 (42%), Gaps = 13/189 (6%)
Query: 176 VAIQMITLIEELHDHDLIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHI 235
V +QM+ I+ LH I+R+I P +F G D + L DF A+ + + K+H+
Sbjct: 206 VGLQMLRAIQNLHSIGYIHRNISPASFHCGLGM--DEPTLFLQDFRQARKFEE--NKKHV 261
Query: 236 PYREKKSLSGTARYMSINTHLGREQSRRDDMEALGHVFFYFL-RGQLPWQGLKAANNKLK 294
R + G R+ + ++Q R+DD+E+ + FY + G L W K NN L
Sbjct: 262 TARTNVKMYGCGRFANRACQGSKDQGRKDDLESWVYTLFYLMDNGSLSW---KRENNSLV 318
Query: 295 YEKIGEKKRSTNVYDLSQGLPVQFGRYLEIVRNLGFEETPDYEGYRKLL--LSVLDELGQ 352
+ + + N D P L ++ F PDYE +R L + + L +
Sbjct: 319 VIQQKDAFMAGNGKDQFTHAPRDLVPLLSVINGYEFSSAPDYEVFRNCLEGIQTVQNLNK 378
Query: 353 KLDGEYDWM 361
K DW+
Sbjct: 379 K---SCDWL 384
>CE00935 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 351
Score = 95.5 bits (236), Expect = 2e-19
Identities = 80/301 (26%), Positives = 136/301 (44%), Gaps = 14/301 (4%)
Query: 72 IVGLHYKIGKKIGEGSFGVLFEGVNMIN-NVPVAIKFEPRKTDAPQLKDEYRTYKILSGS 130
I+ +KI +K+GEG G +F+ ++ A+K E +D LK E K L+
Sbjct: 12 IIAKRWKIVEKLGEGGMGAVFKVRDLTRFQTYAAMKVEGDVSDGGVLKLEAHVLKSLAPL 71
Query: 131 EGIPQAYYFGQEGLHNILVIDLLGPSL-EDLFDWCGRRFSIKTVVHVAIQMITLIEELHD 189
+ G + +V+ LLG L D RF +T + +A+ + I+++H+
Sbjct: 72 PFCARLMDAGDRKSYCFMVMTLLGKDLMAHKRDANTPRFCEQTTLRLAMATLFAIKQIHE 131
Query: 190 HDLIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKS----LSG 245
+RDIKP N + G + DA V+LID+GM + + + R +S G
Sbjct: 132 VGFTHRDIKPGNCVTG-VHGSDAKNVYLIDYGMVRQFTAKRENGETALRRARSGEQLFRG 190
Query: 246 TARYMSINTHLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKAANNKLKYEKIGEKKRST 305
T RY S+N H +EQ R DD+ + ++ G LPW+ L ++I + K +
Sbjct: 191 TPRYCSMNVHNRKEQGRVDDLWSWLYMLIELHCG-LPWRRL------TDEKEIMDAKIAC 243
Query: 306 NVYDLSQGLPVQFGRYLEIVRNLGFEETPDYEGYRKLLLSVLDELGQKLDGEYDWMKLNG 365
++ L +G P +F + + L ++ PDY G + + G ++W G
Sbjct: 244 SMETLLKGCPKEFANIHKYLETLEYKSRPDYFGLWSECFAGFKRVRGSFFGRFEWELGKG 303
Query: 366 G 366
G
Sbjct: 304 G 304
>CE09979 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 311
Score = 95.1 bits (235), Expect = 2e-19
Identities = 80/291 (27%), Positives = 133/291 (45%), Gaps = 17/291 (5%)
Query: 77 YKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPRKTDAPQLKDEYRTYKILS--GSEGIP 134
+ I KK+GEG G ++ + A+K E LK E L+ GS
Sbjct: 20 WSITKKLGEGGCGAVYLCTDATGKY--ALKVEGISEAMQVLKMEVLVLGELTKRGSRHFC 77
Query: 135 QAYYFGQEGLHNILVIDLLGPSLEDLFDWCGRR-FSIKTVVHVAIQMITLIEELHDHDLI 193
+ G+ G N +V+ L+G SL+DL ++ S+ + V IQ + +E+LH+ +
Sbjct: 78 KIEDKGRYGSFNYVVMTLVGKSLQDLRKGTAQQCLSLACSLSVGIQSLEALEDLHNIGYL 137
Query: 194 YRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTARYMSIN 253
+RD+KP N+ IGR + V+++DFGMA+ + D P R GT RY I
Sbjct: 138 HRDVKPGNYTIGRAELNELRKVYILDFGMARKFTDNNGVIRKP-RAAAGFRGTVRYAPIA 196
Query: 254 THLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKAANNKLKYEKIGEKKRS-TNVYDLSQ 312
H +E R+DD+E ++ G++PW+ + N +G+ K++ N +
Sbjct: 197 CHKNQELGRKDDVEVWLYMQVELTVGRVPWKEITDMN------AVGQAKQAIRNTPEKMF 250
Query: 313 GLPVQFGRYLEIVR---NLGFEETPDYEGYRKLLLSVLDELGQKLDGEYDW 360
P EI++ + + P+Y +L+ L G K + YDW
Sbjct: 251 VFPCPANELKEIMKMVDSWDYFADPNYADCYRLMKQTLANCG-KPEYPYDW 300
>CE07449 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 311
Score = 95.1 bits (235), Expect = 2e-19
Identities = 80/291 (27%), Positives = 133/291 (45%), Gaps = 17/291 (5%)
Query: 77 YKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPRKTDAPQLKDEYRTYKILS--GSEGIP 134
+ I KK+GEG G ++ + A+K E LK E L+ GS
Sbjct: 20 WSITKKLGEGGCGAVYLCTDATGKY--ALKVEGISEAMQVLKMEVLVLGELTKRGSRHFC 77
Query: 135 QAYYFGQEGLHNILVIDLLGPSLEDLFDWCGRR-FSIKTVVHVAIQMITLIEELHDHDLI 193
+ G+ G N +V+ L+G SL+DL ++ S+ + V IQ + +E+LH+ +
Sbjct: 78 KIEDKGRYGSFNYVVMTLVGKSLQDLRKGTAQQCLSLACSLSVGIQSLEALEDLHNIGYL 137
Query: 194 YRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTARYMSIN 253
+RD+KP N+ IGR + V+++DFGMA+ + D P R GT RY I
Sbjct: 138 HRDVKPGNYTIGRAELNELRKVYILDFGMARKFTDNNGVIRKP-RAAAGFRGTVRYAPIA 196
Query: 254 THLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKAANNKLKYEKIGEKKRS-TNVYDLSQ 312
H +E R+DD+E ++ G++PW+ + N +G+ K++ N +
Sbjct: 197 CHKNQELGRKDDVEVWLYMQVELTVGRVPWKEITDMN------AVGQAKQTIRNTPEKMF 250
Query: 313 GLPVQFGRYLEIVR---NLGFEETPDYEGYRKLLLSVLDELGQKLDGEYDW 360
P EI++ + + P+Y +L+ L G K + YDW
Sbjct: 251 VFPCPANELKEIMKMVDSWDYFADPNYADCYRLMKQALANCG-KPEYPYDW 300
>CE15314 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 390
Score = 94.4 bits (233), Expect = 4e-19
Identities = 68/240 (28%), Positives = 115/240 (47%), Gaps = 18/240 (7%)
Query: 77 YKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPRKTDAPQLKDEYRTYKILSGSEGIPQA 136
Y++ K + G+FG +++ + A+K E + L R ++ S P
Sbjct: 21 YEVTKPLATGTFGSIYKAKRESDGKFFAVKCEALNMKSSLL----RQMSVVLASIHYPSP 76
Query: 137 YYFGQEGLHNI------LVIDLLGPSLEDLFDWCG--RRFSIKTVVHVAIQMITLIEELH 188
++ E + +V+ L G +L DL R+FS+ T +H+A Q +T I +LH
Sbjct: 77 FFTTIEERGTVPNRFLFIVMPLYGENLFDLMMNTNKDRKFSMATGLHLAEQTLTAIRDLH 136
Query: 189 DHDLIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKS---LSG 245
+ I+RDIKP +F IGR + V+L+DFG+ K R K + +K+ G
Sbjct: 137 RNGFIHRDIKPSHFCIGREVDGQHHQVYLLDFGLCKRPRFAKKNDEAEEQMRKNAIHYRG 196
Query: 246 TARYMSINTHLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKAANNKLKYEKIGEKKRST 305
+Y S++ H G+ +DDME+ ++ F G LPW L N + + + + K+R T
Sbjct: 197 VVKYASVHAHQGKNLGYKDDMESWWYMVLEFFLGALPWALL---NKESEQDVLHLKRRIT 253
>CE04980 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 361
Score = 94.4 bits (233), Expect = 4e-19
Identities = 57/220 (25%), Positives = 113/220 (50%), Gaps = 6/220 (2%)
Query: 83 IGEGSFGVLFEGVNMINNVPVAIKFEPRKTDAPQLKDEYRTYKILSGSEG---IPQAYYF 139
IG+G +G ++ ++++ VAIK EP+K K +L+ +G +P Y
Sbjct: 68 IGKGGYGEIYLALDVVRGEEVAIKVEPKKRRGKLAKRMILEQHVLAKMQGKPHVPMIYGS 127
Query: 140 GQEGLHNILVIDLLGPSLEDLFDWC-GRRFSIKTVVHVAIQMITLIEELHDHDLIYRDIK 198
G +N +++ +L ++ D+ ++ S +V + Q+I +++LH+ ++RD+K
Sbjct: 128 GHAEKYNFIIMQILSINVGDIKKSSPNKKLSQCSVGRIIHQVIAALQDLHETGYVHRDVK 187
Query: 199 PDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTARYMSINTHLGR 258
P N G ++ L+DFG+ + Y+ + P R + GT RY+SI H
Sbjct: 188 PANMCFGIFPHSRHTLI-LLDFGLVRRYKMESGEWREP-RLRAGFRGTTRYVSIRVHRRC 245
Query: 259 EQSRRDDMEALGHVFFYFLRGQLPWQGLKAANNKLKYEKI 298
EQS DD+ ++ + + L G+LPW+ L+ + ++ +++
Sbjct: 246 EQSPYDDLVSVMYTAYELLAGELPWKHLEKSEEVVQLKEV 285
>CE19741 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 330
Score = 92.8 bits (229), Expect = 1e-18
Identities = 73/277 (26%), Positives = 129/277 (46%), Gaps = 15/277 (5%)
Query: 77 YKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPRKTDA-PQLKDEYRTYKILSGSEGIPQ 135
YK+ I G F +F + + VP A+K E K+ P LK ++ L G P
Sbjct: 26 YKLSAPIATGPFSSVF--LVEEDGVPYAMKVEAEKSCVRPVLKLDHAVLTALGNQTGFPS 83
Query: 136 AYYFGQEGLHNILVIDLLGPSLEDLFDWCGR-RFSIKTVVHVAIQMITLIEELHDHDLIY 194
G+ +V+ L+GP L L ++ + RFS T+ +A+Q + + LH +
Sbjct: 84 LMDSGRTDSFKYIVMQLVGPDLSTLLEFAPQNRFSQSTIYKIALQTLDRLRVLHHAGWLN 143
Query: 195 RDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTARYMSINT 254
RD+K NF +G ++N+V+++DFG+ + + + +H+ R GT Y +++
Sbjct: 144 RDVKAQNFAVGFGE--ESNIVYMLDFGLTRRFLELDGSRHL-LRPWGPSVGTFPYAPLSS 200
Query: 255 HLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKAANNKLKYEKIGEKK----RSTNVYDL 310
+Q+ DD+E ++ + L G LPW K L K+ E K R+ L
Sbjct: 201 LGFLDQTPADDVEGWLYMIIHLLNG-LPWHNSK---RSLSLAKVREWKMYCRRAGGRTQL 256
Query: 311 SQGLPVQFGRYLEIVRNLGFEETPDYEGYRKLLLSVL 347
+ +P + +I+ ++E PDY ++S+L
Sbjct: 257 FRDIPDGWSDVFDIILKTSYQEYPDYTKILNKVMSML 293
>CE22732 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 421
Score = 92.4 bits (228), Expect = 2e-18
Identities = 93/388 (23%), Positives = 161/388 (40%), Gaps = 60/388 (15%)
Query: 77 YKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPRKTDAPQLKDEYRTYKILSGSEGIPQA 136
Y++ K + G+FG +++ + A+K E + L R ++ S P
Sbjct: 21 YEVTKPLATGTFGSIYKVKRESDGKFFAVKCEALNMKSSLL----RQMSVVLASIHHPSP 76
Query: 137 YYFGQEGLHNI------LVIDLLGPSLEDLFDWCG--RRFSIKTVVHVAIQMITLIEELH 188
++ E + +V+ L G +L +L R+FS+ T +H+A Q + I +LH
Sbjct: 77 FFTNIEERGTVPNRFLFIVMPLYGENLYELMMNTNKDRKFSMATGLHLAEQTLAAIRDLH 136
Query: 189 DHDLIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKS---LSG 245
+ I+RDIKP +F IGR + V+L+DFG+ K R K + +K+ G
Sbjct: 137 RNGFIHRDIKPSHFCIGREIDGQHHQVYLLDFGLCKRPRFVKKNDEAEEQMRKNAIHYRG 196
Query: 246 TARYMSINTHLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKAANNKLKYEKIGEKKRST 305
+Y S++ H G+ +DDME+ ++ F G LPW L N + + + + K+R T
Sbjct: 197 VVKYASVHAHQGKNLGYKDDMESWWYMVLEFFLGALPWALL---NKESEQDVLHLKRRIT 253
Query: 306 -----NVYDLSQGLPVQFGRYLEIVR-------------------------NLGFEETPD 335
+V+ + F L I+R +E PD
Sbjct: 254 APMVASVWRTTPETTAGFFDLLTIIREPKDVAEFVEYDRIADGIQKLFEKSKSNTQEPPD 313
Query: 336 YE--------GYRKLLLSVLDELGQKLDGEYDWMKLNGGRGWDLAINKKPNLHGYGHPTP 387
++ GY+++L+ E+G L E D+ K + G G + ++P
Sbjct: 314 WDCMTDYKGPGYQQVLMIAPPEVG--LKPEMDFGKSDPGAGGE--SGEQPKKEDVDKKKK 369
Query: 388 PNEKSKRHRNKFNQVPLAVNNLNGSNVP 415
+KSK+ N+ A G P
Sbjct: 370 KKKKSKKKGKSNNKTTSAEEQKGGKCAP 397
>CE20236 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 276
Score = 90.9 bits (224), Expect = 4e-18
Identities = 71/244 (29%), Positives = 119/244 (48%), Gaps = 19/244 (7%)
Query: 76 HYKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPR--KTDAPQLKDEYRTYKILSGSEGI 133
+Y + + +GEG FG ++ + N A+K E + K +LK E K++ +
Sbjct: 23 NYVVSRLLGEGGFGAVYLVKDTKTNKTFAMKVEQKMEKRKHSKLKMEIAILKLVGAGKHF 82
Query: 134 PQAYYFGQEGLHN--ILVIDLLGPSLEDLFDWCGRR-FSIKTVVHVAIQMITLIEELHDH 190
Q G++ LV++L+G SL DL + R FS T + VA Q + +E+LH
Sbjct: 83 TQIVDRGKKDKEGYFFLVMELVGKSLGDLKNERAERVFSFGTGLGVASQCLEAVEDLHRT 142
Query: 191 DLIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTARYM 250
I+RD+KP N+ G + + ++++DFG+A+ Y + K + P RE GT R+
Sbjct: 143 GFIHRDLKPQNYACGLDEK--RHNIYILDFGIARKYLNTKNELKTP-REAVGFKGTVRFA 199
Query: 251 SINTHLGREQSRRDDMEALGHVFFYFL------RGQLPWQGLKAANNKLKYEKIGEKKRS 304
+ H E RDD E+ +FY L RG LPW+ + LK ++ K++
Sbjct: 200 PLACHRFTELGPRDDCES----WFYLLLDLILPRG-LPWRKMNEKGEVLKEKEECRKEKR 254
Query: 305 TNVY 308
++
Sbjct: 255 DKLF 258
>CE12416 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 555
Score = 90.9 bits (224), Expect = 4e-18
Identities = 69/251 (27%), Positives = 123/251 (48%), Gaps = 22/251 (8%)
Query: 125 KILSGSEGIPQAYYFGQEGLHN---ILVIDLLGPSLEDLFDWCGRRFSIKTVVHVAIQMI 181
+I+ + P A + +G++ +V+ L GP L+ + + F+ T++ V I+ +
Sbjct: 13 EIMVAMQHEPTAIHIYDDGIYKDYRYIVMTLCGPDLQKIAELMNNNFNQDTIIRVCIRTL 72
Query: 182 TLIEELHDHDLIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLY--RDPKTKQHIPY-R 238
I+ +H++ I+RD+KP NF + P++ V+L D+GMA+ Y +D K + R
Sbjct: 73 LAIKTMHEYTYIHRDLKPCNFAV--DFNPNSLHVYLFDYGMARKYATKDSGNKWQLRRPR 130
Query: 239 EKKSLSGTARYMSINTHLGREQSRRDDMEALGHVFFYFLR---GQLPWQGLKAANNKLKY 295
GT RY S+N H +E SR DD+ + +F+ L LPW ++N +
Sbjct: 131 NPAQFRGTVRYCSLNMHKRKELSRVDDLWS----WFFMLMEMYAPLPW---TSSNIPERI 183
Query: 296 EKIGEKKRSTNVYDLSQGLPVQFGRYLEIVRNLGFEETPDYEGYRKLLLSVLDELGQKLD 355
E + K+ N Y F +E + ++ + + PDY +L + L E+ KL
Sbjct: 184 EAL--KEDHLNEYLSKDSFLSSFLPLVEYLNSVQYADRPDYMKIYDILYAKLTEINGKLS 241
Query: 356 G--EYDWMKLN 364
G +YD ++N
Sbjct: 242 GPMKYDVARIN 252
>CE16168 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 794
Score = 90.5 bits (223), Expect = 6e-18
Identities = 67/205 (32%), Positives = 102/205 (49%), Gaps = 22/205 (10%)
Query: 148 LVIDLLGPSLEDLFDWCGRRFSIK-----TVVHVAIQMITLIEELHDHDLIYRDIKPDNF 202
+V+ L+GPSL+D C R+F + T +AIQ + I +LH+ ++RDIKP NF
Sbjct: 549 IVMSLVGPSLDD----CRRKFGVNLSNTSTPYIIAIQTLESIRDLHNLGYLHRDIKPANF 604
Query: 203 LIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTARYMSINTHLGREQSR 262
+G + V ++DFG+ + Y DPKTKQH R+K GT RY S L +Q R
Sbjct: 605 AVGVGAKEST--VFMLDFGIGRSYLDPKTKQHRAPRKKVKFLGTLRYASRACMLEVDQGR 662
Query: 263 RDDMEALGHVFFYFLRGQLPWQGLKAANNKLKYEKIGEKKR----STNVYDLSQGLPVQF 318
+DD+E ++ F P G+ + + KI E K+ YD + P+
Sbjct: 663 KDDLECWIYMVFDIFD---PKNGVSWKKQRDRV-KIREAKQLFFDGKAQYDYA---PISL 715
Query: 319 GRYLEIVRNLGFEETPDYEGYRKLL 343
+ + +L F+ TP+Y K L
Sbjct: 716 RPIIIYINSLQFQTTPEYANLVKTL 740
Score = 78.2 bits (191), Expect = 3e-14
Identities = 48/198 (24%), Positives = 98/198 (49%), Gaps = 8/198 (4%)
Query: 166 RRFSIKTVVHVAIQMITLIEELHDHDLIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKL 225
+ ++ +VA+Q + I+ LH + R+IKP +F +G + +++ D+ + +
Sbjct: 215 KALTVPCAFNVALQTLDAIQYLHQAGFLNRNIKPASFSVGL--NEEETKIYMTDYRLVRT 272
Query: 226 YRDPKTKQHIPYREKKSLSGTARYMSINTHLGREQSRRDDMEALGHVFFYFL--RGQLPW 283
+ DP TK+ P R GTARY SI ++Q R+DD+EA ++ + + L W
Sbjct: 273 HIDPSTKKVRPARTGLKYGGTARYASIAGLKKKDQGRKDDVEAWIYMIYDLIDPENGLSW 332
Query: 284 QGLKAANNKLKYEKIGEKKRSTNVYDLSQGLPVQFGRYLEIVRNLGFEETPDYEGYRKLL 343
+ N +K ++ + + YD +P +F + +++V ++ PDY +++++
Sbjct: 333 RKSPRCNMMIKEKENFKYHVLPHTYD---KVPEEFKKLVDLVHGYSYDSLPDYAAFKEIV 389
Query: 344 LSVLDELGQKLDGEYDWM 361
+V G + DW+
Sbjct: 390 QNVGKSKGHDMT-TCDWV 406
>CE17237 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 550
Score = 89.4 bits (220), Expect = 1e-17
Identities = 76/298 (25%), Positives = 140/298 (46%), Gaps = 26/298 (8%)
Query: 81 KKIGEGSFGVLFEGVNMINNVPVAIKFEP-RKTDAPQLKDEYRTYKILSGSEGIPQAYYF 139
K +G G+FG + VN+++ A+K E ++ + LK E + LSG + Q
Sbjct: 26 KVLGSGAFGKVVHVVNIVDGSDGAMKMEKYQEGNESVLKGEVEVLRALSGQKNAIQLLDS 85
Query: 140 GQEGLHNILVIDLLGPSLEDLFDWCGRRFSIKTVVHVAIQMITLIE-------------- 185
G E + +V+ L G L+ +++ +FS TV+ VAI+ + ++
Sbjct: 86 GLEPDYRFIVMTLCGMDLQKVYNLLKGQFSDSTVLRVAIRSLHAVKAVWEYYFIGTELFR 145
Query: 186 -ELHDHDLIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKS-- 242
+LH+ I+RD+KP N + + ++ LIDFGM + Y +++ R + +
Sbjct: 146 TKLHEACYIHRDLKPCNVTLDYNEY--SPLIFLIDFGMGRKYAKIDEGEYVIRRPRDACR 203
Query: 243 LSGTARYMSINTHLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKAANNKLKYEKIGEKK 302
GT RY S HL REQ R DD+ A ++ L+ +LPW + +++++ K+
Sbjct: 204 FRGTIRYCSPRMHLRREQGRVDDLYAWLYMIVE-LKVELPWSEV-VHPDRIEFLKL---- 257
Query: 303 RSTNVYDLSQGLPVQFGRYLEIVRNLGFEETPDYEGYRKLLLSVLDELGQKLDGEYDW 360
+ S L F ++ ++ L + + P+Y +LL ++ +L K D+
Sbjct: 258 EKFDAAMASNPLTKSFEPIMDHLKTLRYPDRPNYLMIYELLAKMMSDLNAKHTDPMDY 315
>CE09897 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 347
Score = 89.0 bits (219), Expect = 2e-17
Identities = 78/298 (26%), Positives = 140/298 (46%), Gaps = 15/298 (5%)
Query: 73 VGLHYKIGKKI-GEGSFGVLFEGVNMINNVPVAIKFEPRKTDAPQLKDEYRTYKILSGSE 131
+G ++K+ K I + F ++ ++ A+K E RKT+A ++ ++ + +L+ +
Sbjct: 38 IGKNWKVVKAIQSDKGFNTIYVAEHVQKKKLAAVKVE-RKTEAIKML-QFELFVLLTVEK 95
Query: 132 G-----IPQAYYFGQEGLHNILVIDLLGPSLEDLFDWCGR-RFSIKTVVHVAIQMITLIE 185
+ + G E +N + I L G SL L + + ++ + VA Q + +E
Sbjct: 96 KNQCKQFCKLFEKGNEKEYNWIAITLCGKSLRALRKNQPKGKLTVACGLSVAQQCLKGLE 155
Query: 186 ELHDHDLIYRDIKPDNFLIGR---PNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKS 242
ELH I+R++ P F IGR NQ D ++++DFG A Y + P
Sbjct: 156 ELHRMGFIHRNVAPSVFAIGRYTGDNQSDMRNIYILDFGFAHQYMNKDGTLKPPSAHPWK 215
Query: 243 LSGTARYMSINTHLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKAANNKLKYEKIGEKK 302
G+ R+M E SR +D+E ++ ++G LPW LK Y+K+ +
Sbjct: 216 YVGSLRHMPRAAFSKVEFSRMEDLEMWFYMSVELVKGCLPWAHLKKPKEVHDYQKL--CR 273
Query: 303 RSTNVYDLSQGLPVQFGRYLEIVRNLGFEETPDYEGYRKLLLSVLDELGQKLDGEYDW 360
+ ++ GLP +F +++V L F +TP+Y+ LL + + G K + YDW
Sbjct: 274 NGLQMREMLGGLPPEFFDIMQMVDKLSFTDTPNYKEIYGLLTNAILFSG-KNEFPYDW 330
>CE00873 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 363
Score = 89.0 bits (219), Expect = 2e-17
Identities = 57/209 (27%), Positives = 108/209 (51%), Gaps = 6/209 (2%)
Query: 83 IGEGSFGVLFEGVNMINNVPVAIKFEPR---KTDAPQLKDEYRTYKILSGSEGIPQAYYF 139
IG G +G +F +++ N A+K EP+ + ++ E + + G IP Y
Sbjct: 78 IGNGGYGQIFMVMDVKKNDERAMKIEPKLRAEVITKRMIMEQQVLMKMQGKTHIPTMYAS 137
Query: 140 GQEGLHNILVIDLLGPSLEDLFDWCGR-RFSIKTVVHVAIQMITLIEELHDHDLIYRDIK 198
G N +++ LL ++ D R S +TV +A Q + ++++HD ++RD+K
Sbjct: 138 GFNDQFNFIIMQLLSMNVGDFRKRSPLGRLSKETVGRIAYQTLNALKDIHDMGYVHRDVK 197
Query: 199 PDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTARYMSINTHLGR 258
P N G Q + ++++L+DFG+ + ++ ++ IP+R GT RY+S+ H
Sbjct: 198 PANICFGVHAQ-NRHILYLLDFGLVRRFKT-ESGVCIPWRINAGFKGTERYVSVRVHEKL 255
Query: 259 EQSRRDDMEALGHVFFYFLRGQLPWQGLK 287
EQ+ DD ++ + + + G+LPW+ L+
Sbjct: 256 EQTPWDDAFSVLYTAYELVVGELPWRYLE 284
>CE16891 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 357
Score = 86.7 bits (213), Expect = 8e-17
Identities = 77/298 (25%), Positives = 137/298 (45%), Gaps = 14/298 (4%)
Query: 73 VGLHYKIGKKI-GEGSFGVLFEGVNMINNVPVAIKFEPRKTDAPQLKDEYRTYKILSGSE 131
+G ++K+ K I + F ++ ++ +A RKT+A ++ ++ + +L+ +
Sbjct: 44 IGKNWKVVKAIQSDKGFNTIYVAEHVQKKKKMAAVKVERKTEAIKML-QFELFVLLTVEK 102
Query: 132 G-----IPQAYYFGQEGLHNILVIDLLGPSLEDLF-DWCGRRFSIKTVVHVAIQMITLIE 185
+ + G E +N + I L G SL L + + ++ + VA Q + +E
Sbjct: 103 KNQCKQFCKLFEKGNEKEYNWIAITLCGKSLRALRKNQPTGKLTVACGLSVAQQCLKGLE 162
Query: 186 ELHDHDLIYRDIKPDNFLIGR---PNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKS 242
ELH I+R++ P F IGR NQ D ++++DFG A Y P
Sbjct: 163 ELHRMGFIHRNVAPSVFAIGRYTGDNQSDLRNIYILDFGFAHQYMIKDGTLKPPSAHPWK 222
Query: 243 LSGTARYMSINTHLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKAANNKLKYEKIGEKK 302
G+ R+M + E SR +D+E ++ ++G LPW LK Y+K+ +
Sbjct: 223 YVGSLRHMPRAAYSKVEFSRMEDLEMWFYMSVELVKGCLPWAHLKKPKEVHDYQKL--CR 280
Query: 303 RSTNVYDLSQGLPVQFGRYLEIVRNLGFEETPDYEGYRKLLLSVLDELGQKLDGEYDW 360
+ ++ GLP +F ++IV L F +TP+Y LL + + G K + YDW
Sbjct: 281 NGLQMREMLGGLPPEFVDIMQIVDKLSFTDTPNYTEIYGLLTNAILFSG-KNEFPYDW 337
>CE24572 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 382
Score = 83.2 bits (204), Expect = 9e-16
Identities = 58/219 (26%), Positives = 106/219 (47%), Gaps = 7/219 (3%)
Query: 77 YKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPRKTDAPQLKDEYRTYKILSGSEGIPQA 136
Y++ ++G+GSFG +F + A+K E L E L+ + P
Sbjct: 70 YELTSELGQGSFGAVFGVTRKSDKRHFAMKCESVNMKRAILPHEAGVLLALNHLKS-PHF 128
Query: 137 YYFGQEGLHN----ILVIDLLGPSLEDLFDWC-GRRFSIKTVVHVAIQMITLIEELHDHD 191
G+ N +V+ L+G +L D+ +++++ T + +A Q + + +LH
Sbjct: 129 LEMVDHGIVNNRFLFVVLKLVGMNLWDMRAHLPDKKYTLTTTLRIAEQTLAGLRDLHRVG 188
Query: 192 LIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTARYMS 251
++RDIKP NF IGR + V L+DFG+ + K K R++ + GT RY +
Sbjct: 189 FLHRDIKPPNFAIGREEDDTYHTVFLLDFGLCRKIA-MKGKDLRTPRKECAFRGTTRYAA 247
Query: 252 INTHLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKAAN 290
+ H +EQSR+DD+E+ ++ + +PW+ + +
Sbjct: 248 LAAHDNKEQSRKDDIESWWYMIAEMIVFDIPWKQFRGTD 286
>CE02965 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 405
Score = 79.7 bits (195), Expect = 1e-14
Identities = 77/301 (25%), Positives = 142/301 (46%), Gaps = 29/301 (9%)
Query: 77 YKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPRKTDA--PQLKDEYRTYKILS--GSEG 132
Y++ + IGEG++G +F+ N A+K EP + D + E L+ G++
Sbjct: 25 YQVVESIGEGAYGQVFKVSK--NAKKYAMKVEPNRLDGGPASITKEIEVMMELNNRGAKF 82
Query: 133 IPQAYYFGQEGLHNILVIDLLGPSLEDL-FDWCGRRFSIK-TVVHVAIQMITLIEELHDH 190
P G+E +++V+ LLG +L+ L C + T + IQ + +++++HD
Sbjct: 83 FPIFETGGREPKFHMVVMTLLGENLQVLRMKGCNPKACTPGTWSRIGIQCLFVVKQMHDC 142
Query: 191 DLIYRDIKPDNFLIGRPNQP-DANMVHLIDFGMAKLY-----RDPKTKQH-IPYREKK-- 241
+++ D+KP NF+ G+ ++ + +LIDFG+++ + P +Q+ +R +K
Sbjct: 143 GILHHDLKPTNFVWGQSDEALTCRVFYLIDFGISRKFIRHVKGTPINQQNGFEFRTEKKK 202
Query: 242 --SLSGTARYMSINTHLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKAANNKLKYEKIG 299
SL GT +Y S H + R DD+ +L ++ ++ LPW+ L+A L+ K+
Sbjct: 203 VHSLVGTPKYTSPKAHAMADLGRGDDLWSLMYMIAELVK-PLPWEILEA--KMLENTKLK 259
Query: 300 EKKRSTNVYDLSQGLPVQFGRYLEIVRNLGFEETPDYEGYRKLLLSVLDELGQKLDGEYD 359
K + D FG+ ++ F P+YE V ++ G YD
Sbjct: 260 SKLKDHFGMD-------GFGKIETMLHACTFNSFPNYEMIYLAFKEVFNKSGVSWLDPYD 312
Query: 360 W 360
W
Sbjct: 313 W 313
>CE02499 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 211
Score = 79.3 bits (194), Expect = 1e-14
Identities = 49/194 (25%), Positives = 95/194 (48%), Gaps = 3/194 (1%)
Query: 77 YKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPRKTDAPQLKDEYRTYKILS--GSEGIP 134
YK+ K +G GS+G + E + + A+K E P L +E + K + S+ +
Sbjct: 19 YKVTKLLGGGSYGCVHEVIELKTGDRYAMKSEYSSMKKPILLNELKVMKAIYTFSSQHVL 78
Query: 135 QAYYFGQEGLHNILVIDLLGPSLEDLFDWCGRRFSIKTVVHVAIQMITLIEELHDHDLIY 194
+ G G +++ +L +++++F+ G ++ T V + Q + +E +H ++
Sbjct: 79 KVRDMGVHGSTKFIIMQMLEKNMDEVFELLGGSMTLNTAVATSYQCLEGLEFMHWAGFLH 138
Query: 195 RDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTARYMSINT 254
RDIKP+N+ + + +++ID+G+ K + D P R+ GT + I +
Sbjct: 139 RDIKPNNYCLDANSGQGLRTIYIIDYGICKRFVDNNNVIRQP-RKITKFRGTLDFAPIVS 197
Query: 255 HLGREQSRRDDMEA 268
H RE SR D+E+
Sbjct: 198 HELREHSRGSDLES 211
>CE24727 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 331
Score = 79.0 bits (193), Expect = 2e-14
Identities = 52/168 (30%), Positives = 88/168 (51%), Gaps = 5/168 (2%)
Query: 139 FGQEGLHNILVIDLLGPSLEDL-FDWCGRRFSIKTVVHVAIQMITLIEELHDHDLIYRDI 197
FGQ + +V+ ++GPSLE+L + T++ +Q + I + H ++RDI
Sbjct: 58 FGQSPVWKWIVMTIVGPSLEELKMKYKPSDIPPSTILQCGLQTMKAIHDFHQIGFLHRDI 117
Query: 198 KPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTARYMSINTHLG 257
KP N+ IG ++ + ++++DFG+A+ YR P Q P R K + GT RY S +H
Sbjct: 118 KPANYCIGYGSKSET--IYVLDFGLARKYRLP-NGQVRPPRPKTKMIGTPRYCSRASHRC 174
Query: 258 REQSRRDDMEALGHVFFYFLRGQL-PWQGLKAANNKLKYEKIGEKKRS 304
E RRDD E+ +F + L W+GL + K +++ K ++
Sbjct: 175 EELGRRDDYESWFFMFIDLVDTTLIDWKGLTRPDAYAKKQELFTKLKT 222
>CE17143 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 338
Score = 78.2 bits (191), Expect = 3e-14
Identities = 58/208 (27%), Positives = 96/208 (45%), Gaps = 13/208 (6%)
Query: 77 YKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPRKTDAPQLKDEYRTYKILSGSEGIPQA 136
Y I +KI EGSFG +F+ + +K E + + L+ E T + S +P+
Sbjct: 22 YTINEKIAEGSFGAIFKVTEKSTGTRLVLKAELPGSPSNDLRIELVTMLRVFRSY-VPEV 80
Query: 137 YYFGQEGLHNILVIDLLGPSLEDLFDWC-GRRFSIKTVVHVAIQMITLIEELHDHDLIYR 195
G L++ L G SLED+ G + S+ T + + +H ++R
Sbjct: 81 TDKGVFNGTKFLIMPLFGKSLEDIIGALPGNKCSLSTAIGHRV--------VHWSHYLHR 132
Query: 196 DIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTARYMSINTH 255
D+KP NF +G + D + L+DFGM++ Y + P R + GT Y +H
Sbjct: 133 DLKPGNFCVG--SGKDIRRIFLVDFGMSRRYCGQDNVIYQP-RTRCQFRGTPVYAPRASH 189
Query: 256 LGREQSRRDDMEALGHVFFYFLRGQLPW 283
E +R+ D+E+ G++ G+LPW
Sbjct: 190 NRAEHNRKSDLESWGYMMIEMTTGKLPW 217
>CE07685 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 373
Score = 78.2 bits (191), Expect = 3e-14
Identities = 71/271 (26%), Positives = 120/271 (44%), Gaps = 23/271 (8%)
Query: 77 YKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPRKTDAPQ-LKDEYRTYKILSGSEGIPQ 135
++I KK+G G FG +++ N +A+K E T++ LK+E ++L S G +
Sbjct: 21 FEIIKKLGSGGFGAVYQVRK--NGFDMALKTEFVDTESDDTLKNEAHILRLLQWSPGFCR 78
Query: 136 AYYFGQEGLH----NILVIDLLGPSLEDLFDWC-GRRFSIKTVVHVAIQMITLIEELHDH 190
Y + + NI+ + L + L + FS T +++Q++ + ++H
Sbjct: 79 LYTAKRLTWNKQQVNIMAMSLCARPISRLRRMMPDKHFSKSTAARLSVQLLEALRDMHAS 138
Query: 191 DLIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYR--DPKTK--QHIPYREKKSLSGT 246
+I+RD+K N + + L D G ++ Y DP T +H R+ GT
Sbjct: 139 GIIHRDVKGSNC----GWHASSRRILLFDLGFSRKYLELDPSTNTMRHRAARKTPGFMGT 194
Query: 247 ARYMSINTHLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKAANNKLKYEKIGEKKRSTN 306
+ Y S H +Q RRDD+ A + G LPW NN+ K + + K+
Sbjct: 195 SNYCSTYAHDECDQGRRDDLWAWLYSTVEMFLGSLPW------NNEDKTILVSKMKKKIG 248
Query: 307 VYDLSQGLPVQFGRYLEIVRNLGFEETPDYE 337
L P + E +R L F+ TPDY+
Sbjct: 249 -KKLFFKCPREIALMYEHIRQLKFDSTPDYQ 278
>CE01404 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 370
Score = 78.2 bits (191), Expect = 3e-14
Identities = 39/121 (32%), Positives = 76/121 (62%), Gaps = 2/121 (1%)
Query: 148 LVIDLLGPSLEDLFDWCGRRFSIKTVVHVAIQMITLIEELHDHDLIYRDIKPDNFLIGRP 207
+V+ L+GPSLE + R+++ V+++A+Q++ +E +H+ I+RD+KP N G P
Sbjct: 78 IVMTLIGPSLESVRRMLKRQYTKSCVINMALQILDAVEVMHEVGFIHRDLKPANICTGTP 137
Query: 208 NQPDANMVHLIDFGMA-KLYRDPKTKQHIPYREKKSLSGTARYMSINTHLGREQSRRDDM 266
Q D ++++++DFG++ ++++ K + RE+ GT ++ S H ++Q R+DDM
Sbjct: 138 PQDD-HVLYVLDFGISRRVFKSSKCHELRNKRERVPFFGTRKFSSRACHQEKDQGRKDDM 196
Query: 267 E 267
E
Sbjct: 197 E 197
>CE24851 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 290
Score = 77.8 bits (190), Expect = 4e-14
Identities = 59/238 (24%), Positives = 109/238 (45%), Gaps = 17/238 (7%)
Query: 133 IPQAYYFGQEGLHNILVIDLLGPSLEDLFDW---CGRRFSIKTVVHVAIQMITLIEELHD 189
IP +G++ + +V+ LLG +L+DL + FS T V IQ + ++ +H
Sbjct: 18 IPNLNLYGKKMNFSYMVMTLLGRNLQDLESTNFVVNKGFSRGTWSRVGIQWVYALKYVHY 77
Query: 190 HDLIYRDIKPDNFLIGRPNQPD-ANMVHLIDFGMAKLY-----RDPKTKQHIPYREKKSL 243
+ I+R++ N +G + A ++H++DFG+ + + R+ K I R
Sbjct: 78 NGFIHRNVNTQNLFLGNEKDSERAKIIHILDFGLGRPFARYHARENKWIVRIA-RHSAEF 136
Query: 244 SGTARYMSINTHLGREQSRRDDMEALGHVFFYFLRGQ-LPWQGLKAANNKLKYEKIGEKK 302
G+ RY S N HL +EQ R DD+ +L +V G+ LPWQ + ++ + K
Sbjct: 137 RGSFRYASPNVHLRKEQGRVDDVWSLPYVIIELNGGKALPWQ------TDYRRGRVEQMK 190
Query: 303 RSTNVYDLSQGLPVQFGRYLEIVRNLGFEETPDYEGYRKLLLSVLDELGQKLDGEYDW 360
+ D+ +P + + + +L + + PD K V++ ++DW
Sbjct: 191 LNLTPKDVMSDMPACMDKLMPHLASLNYYQRPDDHMIFKCFWQVMENEKITPSSKFDW 248
>CE12690 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 425
Score = 76.6 bits (187), Expect = 9e-14
Identities = 80/324 (24%), Positives = 149/324 (45%), Gaps = 30/324 (9%)
Query: 73 VGLHYKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPRKTDAPQLKDEYRTYKILSGSEG 132
+G + IG+ I +G + ++ + A+K E D+ + E + L S
Sbjct: 24 LGSWFSIGE-IAKGDLSTVSRVIDSEGKIEAAMKVEKLSKDSKKRSIEKDVLEALRDS-- 80
Query: 133 IPQAYYFGQE---GLHNILVIDLLGPSLEDLFDWCGRRFSIKTVVHVAIQMITLIEELHD 189
P + + ++ G + V+ L GP+L + +FS T++ ++++ + I++LH+
Sbjct: 81 -PHSAHIIEQLLIGDYRFTVMTLSGPTLGIIKHIMDNKFSDSTILRLSMRTLMAIKDLHE 139
Query: 190 HDLIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLY-RDPKTKQHI-PYREKKSLSGTA 247
H I+RD++P N + P + N++ L+DFG A+ + R+ K + R+K G+
Sbjct: 140 HGFIHRDLEPFNIALS-PYKSSRNIL-LLDFGEARQFARNDNGKWMLRKPRDKAPFRGSD 197
Query: 248 RYMSINTHLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKAANNKLKYEKIGEKKRSTNV 307
+Y S H EQ R DD+ + +VF LR LPW + ++ KY + K+ +
Sbjct: 198 QYCSPRMHNHEEQGRVDDLWSWLYVFVE-LRAFLPWTD---STSRFKYGPL--KRELLDD 251
Query: 308 YDLSQGLPVQFGRYLEIVRNLGFEETPDYEGYRKLLLSVLDELGQKLDGEYDWMKLNGGR 367
S F + ++R + + PDY ++L + + +G K D
Sbjct: 252 LLASDPFITTFCPIVTLLREGKYADRPDYGKIYEILAAKMTSMGVKWTDPMD-------- 303
Query: 368 GWDLAINKKPNLHGYGHPTPPNEK 391
+DL + KPN Y +P NE+
Sbjct: 304 -FDLQAD-KPN---YFSKSPSNEE 322
>CE03487 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 364
Score = 75.9 bits (185), Expect = 1e-13
Identities = 76/293 (25%), Positives = 133/293 (44%), Gaps = 31/293 (10%)
Query: 77 YKIGKKIGEGSFGVLFEG-VNMINNVPVAIKFEPRKTDAPQLKDEYRTYKILSGS---EG 132
+ + K + G FG +FE + +N +K E + L +E K L+ +
Sbjct: 20 FVLQKMLSGGGFGQIFEASIYGSSNEKSVVKVEGQNAMFQLLYNECSCLKSLNTAFNPNN 79
Query: 133 IPQAYYF----GQEGLHNI--LVIDLLGPSLEDLF-DWCGRRFSIKTVVHVAIQMITLIE 185
+P A F G G+ L ++ G +L DL D RFS+ T + + + I ++
Sbjct: 80 LPGASPFLRFHGYGGIDGFRWLAMERCGENLSDLRKDTPLGRFSVTTSLFIFYKFIEALQ 139
Query: 186 ELHDHDLIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLY--RDPKTKQHIPYREKKSL 243
+H ++RD+KP N + ++ ++L+DFGM+K+Y +D K R
Sbjct: 140 MMHSIGWLHRDVKPANVCVDLKSR---RHLYLLDFGMSKIYVEKDGTLKAR---RTSAPF 193
Query: 244 SGTARYMSINTHLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKAANNKLKYEKIGEKKR 303
GT RY+S+N H ++ SR DD+ + ++ + G LPW+ + A K+ EKK
Sbjct: 194 RGTLRYVSVNIHRRQDASRWDDIWSAFYIATENMVGHLPWRRMGDA------MKVEEKKV 247
Query: 304 STNVYDLSQGLPVQFGRYLEIVRN--LGFEETPDY----EGYRKLLLSVLDEL 350
S+++ L G + +E + N + P Y Y K+L + +L
Sbjct: 248 SSDLSRLIYGSDRSRPKCMEYIENELNNSQSDPSYFYVPPAYDKMLQQIAGDL 300
>At5g66210 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 523
Score = 73.9 bits (180), Expect = 6e-13
Identities = 60/215 (27%), Positives = 103/215 (47%), Gaps = 18/215 (8%)
Query: 76 HYKIGKKIGEGSFGVLFEGVNMINNVPVAIK-FEPRKTDAP----QLKDEYRTYKILSGS 130
HY IGK +G G FG + ++ N VA+K + K P +K E + LSG
Sbjct: 61 HYTIGKLLGHGQFGYTYVAIHRPNGDRVAVKRLDKSKMVLPIAVEDVKREVQILIALSGH 120
Query: 131 EGIPQAYYFGQEGLHNILVIDLL--GPSLEDLFDWCGRRFSIKTVVHVAIQMITLIEELH 188
E + Q + ++ + +V++L G L+ + G R+S K V QM+ + E H
Sbjct: 121 ENVVQFHNAFEDDDYVYIVMELCEGGELLDRILSKKGNRYSEKDAAVVVRQMLKVAGECH 180
Query: 189 DHDLIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTAR 248
H L++RD+KP+NFL + Q D+ + DFG++ + P + + G+A
Sbjct: 181 LHGLVHRDMKPENFLF-KSAQLDSPL-KATDFGLSDFIK--------PGKRFHDIVGSAY 230
Query: 249 YMSINTHLGREQSRRDDMEALGHVFFYFLRGQLPW 283
Y++ L R D+ ++G + + L G+ P+
Sbjct: 231 YVAPEV-LKRRSGPESDVWSIGVITYILLCGRRPF 264
>Hs7705993 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 474
Score = 72.4 bits (176), Expect = 2e-12
Identities = 59/225 (26%), Positives = 109/225 (48%), Gaps = 12/225 (5%)
Query: 133 IPQAYYFG-QEGLHNILVIDLLGPSLEDLFDWCGRR-FSIKTVVHVAIQMITLIEELHDH 190
IP FG + + LV+ LG SL+ D + S ++V+ VA +++ +E LH++
Sbjct: 241 IPTCMGFGVHQDKYRFLVLPSLGRSLQSALDVSPKHVLSERSVLQVACRLLDALEFLHEN 300
Query: 191 DLIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYRE--KKSLSGTAR 248
+ ++ ++ +N + + D + V L +G A +R + +H+ Y E + G
Sbjct: 301 EYVHGNVTAENIFV---DPEDQSQVTLAGYGFA--FRYCPSGKHVAYVEGSRSPHEGDLE 355
Query: 249 YMSINTHLGREQSRRDDMEALGHVFFYFLRGQLPWQG-LKAANNKLKYEKIGEKKRSTNV 307
++S++ H G SRR D+++LG+ +L G LPW L + +K ++ K V
Sbjct: 356 FISMDLHKGCGPSRRSDLQSLGYCMLKWLYGFLPWTNCLPNTEDIMKQKQKFVDKPGPFV 415
Query: 308 YDLSQGL--PVQFGRYLEIVRNLGFEETPDYEGYRKLLLSVLDEL 350
+ +YL++V L +EE P Y R L ++L +L
Sbjct: 416 GPCGHWIRPSETLQKYLKVVMALTYEEKPPYAMLRNNLEALLQDL 460
>CE04290 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 359
Score = 72.4 bits (176), Expect = 2e-12
Identities = 69/278 (24%), Positives = 133/278 (47%), Gaps = 29/278 (10%)
Query: 77 YKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPRKTDA--PQLKDEYRTYKILS--GSEG 132
Y++ + IG+G++G +F+ N A+K EP + D + E L+ G++
Sbjct: 25 YQVVESIGDGAYGQVFKVSK--NAKKYAMKVEPNRLDGGPASITKEIEVMMELNNRGAKF 82
Query: 133 IPQAYYFGQEGLHNILVIDLLGPSLEDL-FDWCGRRFSIK-TVVHVAIQMITLIEELHDH 190
P G+E +++V+ LLG +L+ L C + T + IQ + +++++HD
Sbjct: 83 FPIFETGGREPKFHMVVMTLLGENLQVLRMKGCNPKACTPGTWSRIGIQCLFVVKQMHDC 142
Query: 191 DLIYRDIKPDNFLIGRPNQP-DANMVHLIDFGMAKLY-----RDPKTKQH-----IPYRE 239
++ D+KP NF+ G+ ++ + + +LIDFG++ + P +Q+ ++
Sbjct: 143 GFLHHDLKPANFVWGQSDEVLTSRVFYLIDFGISSKFIRHIKGTPINQQNGFEFRTENKK 202
Query: 240 KKSLSGTARYMSINTHLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKAANNKLKYEKIG 299
SL GT +Y S H + R DD +L ++ ++ LPW+ L+A EK
Sbjct: 203 VHSLVGTPKYTSPKAHAMADLGRGDDFWSLMYMIAELVK-PLPWEILEAK----MLEKTK 257
Query: 300 EKKRSTNVYDLSQGLPVQFGRYLEIVRNLGFEETPDYE 337
K + ++Y + FG+ +++ F P+YE
Sbjct: 258 LKSKLKDLYGID-----AFGKIETMLQACTFHSFPNYE 290
>Hs4759052 [T] KOG0603 Ribosomal protein S6 kinase
Length = 809
Score = 72.0 bits (175), Expect = 2e-12
Identities = 67/258 (25%), Positives = 117/258 (44%), Gaps = 31/258 (12%)
Query: 76 HYKIG---KKIGEGSFGVLFEGVNMINNVPVAIKFEPRKTDAPQLKDEYRTYKILSGSEG 132
HY + K +GEGSF + + V+ +N + +K ++ +A K E K+ G
Sbjct: 422 HYDLDLKDKPLGEGSFSICRKCVHKKSNQALQVKIISKRMEANTQK-EITALKLCEGHPN 480
Query: 133 IPQAYYFGQEGLHNILVIDLLGPSLEDLFDWCGRR--FSIKTVVHVAIQMITLIEELHDH 190
I + + + LH LV++LL +LFD ++ FS ++ ++++ + +HD
Sbjct: 481 IVKLHEVFHDQLHTFLVMELLNGG--ELFDALRKKKHFSETEASYIMRKLVSALSHMHDL 538
Query: 191 DLIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTARYM 250
+++RD+KP+N L N D + +IDFG A+L K + P + + R
Sbjct: 539 GVVHRDLKPENLLFTDEN--DNLEIKIIDFGFARL----KPPDNQPLKTPCFTLHSCRPE 592
Query: 251 SINTHLGREQSRRDDMEALGHVFFYFLRGQLPWQG--------------LKAANNKLKYE 296
+N + G ++S D+ +LG + + L GQ+P+Q K +E
Sbjct: 593 LLNQN-GYDES--CDLWSLGVILYTMLSGQVPFQSHDRSLTCTSAVEIMKKIKKGDFSFE 649
Query: 297 KIGEKKRSTNVYDLSQGL 314
K S DL QGL
Sbjct: 650 GEAWKNVSQEAKDLIQGL 667
>YDR490c [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 766
Score = 70.5 bits (171), Expect = 6e-12
Identities = 68/242 (28%), Positives = 112/242 (46%), Gaps = 37/242 (15%)
Query: 77 YKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPRKTDAPQLKDEYRTYKILS-----GSE 131
+K G+++G+GS+ + + A+K ++ Q K +Y T + L+ G++
Sbjct: 125 FKFGEQLGDGSYSSVVLATARDSGKKYAVKVLSKEYLIRQKKVKYVTVEKLALQKLNGTK 184
Query: 132 GIPQAYYFGQEGLHNILVI------DLLG--PSLEDLFDWCGRRFSIKTVVHVAIQMITL 183
GI + ++ Q+ ++ D LG L + C R + A Q+I
Sbjct: 185 GIFKLFFTFQDEASLYFLLEYAPHGDFLGLIKKYGSLNETCARYY--------ASQIIDA 236
Query: 184 IEELHDHDLIYRDIKPDNFLIGRPNQPDANM-VHLIDFGMAKLYRD--PKTKQHIP---- 236
++ LH+ +I+RDIKP+N L+ D NM V L DFG AK+ + T P
Sbjct: 237 VDSLHNIGIIHRDIKPENILL------DKNMKVKLTDFGTAKILPEEPSNTADGKPYFDL 290
Query: 237 YREKKSLSGTARYMSINTHLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKAANNKLKYE 296
Y + KS GTA Y+S R D+ A G + + L G+ P+ KAAN L ++
Sbjct: 291 YAKSKSFVGTAEYVSPELLNDNYTDSRCDIWAFGCILYQMLAGKPPF---KAANEYLTFQ 347
Query: 297 KI 298
K+
Sbjct: 348 KV 349
>CE29038 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 310
Score = 70.5 bits (171), Expect = 6e-12
Identities = 56/200 (28%), Positives = 93/200 (46%), Gaps = 22/200 (11%)
Query: 166 RRFSIKTVVHVAIQMITLIEELHDHDLIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKL 225
+R + +T+ Q++ + +H + ++RDIKP N IG D ++LID+ + +
Sbjct: 94 KRITDRTLYRAMAQVLKALALVHRAEFLHRDIKPPNCCIGAT---DCTRIYLIDYVLTRQ 150
Query: 226 YRDPKTKQHIPYREKKSLSGTARYMSINTHLGREQSRRDDMEALGHVFFYFLRGQLPWQG 285
Y D P R L GT RYMS++ H ++ ++D+ + + G LPW
Sbjct: 151 YLDKCGTVRNP-RPGLGLRGTMRYMSLDAHARQDLGPKNDLVSFLYTTIECGDGCLPWSY 209
Query: 286 LKAANN--KLKYEKIGEKKRSTNVYDLSQGLPVQFGRYLEIVRNLGFEETPDYEGYRKLL 343
K+ N KLK IGEK + + L + Y+E +L + PDYE L
Sbjct: 210 EKSEENCIKLKQAHIGEK------LCIKKPLMTKAAEYIE---SLNYHSIPDYE----KL 256
Query: 344 LSVLDELGQ---KLDGEYDW 360
L++++E K Y+W
Sbjct: 257 LALIEECNPADLKESEPYEW 276
>7303521 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 1004
Score = 70.5 bits (171), Expect = 6e-12
Identities = 45/144 (31%), Positives = 72/144 (49%), Gaps = 11/144 (7%)
Query: 215 VHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTARYMSINTHLGREQSRRDDMEALGHVFF 274
V LIDFG+A ++D + ++++ GT + S + HLG SRR D+E LG+
Sbjct: 521 VFLIDFGLASKFQDRGVHRPFIMDQRRAHDGTLEFTSRDAHLG-AHSRRSDLECLGYNLL 579
Query: 275 YFLRGQLPWQGLKAANNKLKYEKIGEKKR--STNVYDL-----SQGLPVQFGRYLEIVRN 327
Y+ G LPW K + + EK+ K T+V ++ + +P G +L +
Sbjct: 580 YWSEGYLPW---KDVAQQQQQEKVHRAKELFMTDVPEMLRQFYGKQVPKYLGEFLLQIGQ 636
Query: 328 LGFEETPDYEGYRKLLLSVLDELG 351
L ++E P+YE YRK+ LG
Sbjct: 637 LAYQERPNYERYRKIFKREYQRLG 660
>CE09428 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 394
Score = 69.7 bits (169), Expect = 1e-11
Identities = 65/253 (25%), Positives = 102/253 (39%), Gaps = 52/253 (20%)
Query: 147 ILVIDLLGPSLEDLFDWCGRRFSIKTVVHVAIQMITLIEELHDHDLIYRDIKPDNFLIGR 206
IL +DLLG +L + + G + + H+A QMI L+ +HD +++ DIKP NF G
Sbjct: 122 ILQLDLLGLNLLEYAELYGGKLEVPEAFHLARQMIDLLHTIHDRGIVHCDIKPANFAFGL 181
Query: 207 PNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTARYMSINTH----------- 255
+ N ++LIDFG+A+ + D + H + GT YMS N H
Sbjct: 182 NEK--KNQLNLIDFGLAESFLDDR-GNHREVHNRHYRKGTYVYMSANQHHEQCFGKSFLF 238
Query: 256 -----------------------------------LGREQSRRDDMEALGHVFFYFLRGQ 280
L +RRDDME+L + L
Sbjct: 239 AFVSALLIENSAFSKKILLTIPRRKVKPNIFCSNYLITGNTRRDDMESLVYSLRKILDLT 298
Query: 281 LPWQGLKAANNKLKYEKIGEKKRSTNVYDLSQGLPVQFGRYLEIVRNLGFEETPDYEGYR 340
+ W+ ++ NN + K+ G+ L+ R L F++ P+YE +
Sbjct: 299 MCWKEGRSVNNDDTHRNYFNLKQGNQKSCSLCGIQ-PINDMLQSCRMLEFKDEPNYEAVK 357
Query: 341 KLLLSVLDELGQK 353
+L VLD+ K
Sbjct: 358 QLF--VLDKAMSK 368
>At2g46700 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 595
Score = 69.3 bits (168), Expect = 1e-11
Identities = 58/219 (26%), Positives = 104/219 (47%), Gaps = 20/219 (9%)
Query: 74 GLHYKIGKKIGEGSFGVLFEGVNM---INNVPVAIKF--EPRKTDAPQLKDEYRTYKILS 128
G Y++GK++G G FG G I + P+A+K + + T A ++D R K+L
Sbjct: 140 GAKYELGKEVGRGHFGHTCSGRGKKGDIKDHPIAVKIISKAKMTTAIAIEDVRREVKLLK 199
Query: 129 GSEGIPQA--YYFGQEGLHNILVIDLL--GPSLEDLFDWCGRRFSIKTVVHVAIQMITLI 184
G YY E +N+ ++ L G L D G ++ + +Q++T++
Sbjct: 200 SLSGHKYLIKYYDACEDANNVYIVMELCDGGELLDRILARGGKYPEDDAKAIVVQILTVV 259
Query: 185 EELHDHDLIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLS 244
H +++RD+KP+NFL ++ D+++ LIDFG++ R P +
Sbjct: 260 SFCHLQGVVHRDLKPENFLF-TSSREDSDL-KLIDFGLSDFIR--------PDERLNDIV 309
Query: 245 GTARYMSINTHLGREQSRRDDMEALGHVFFYFLRGQLPW 283
G+A Y++ L R S D+ ++G + + L G P+
Sbjct: 310 GSAYYVAPEV-LHRSYSLEADIWSIGVITYILLCGSRPF 347
>CE04444 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 299
Score = 68.9 bits (167), Expect = 2e-11
Identities = 47/162 (29%), Positives = 90/162 (55%), Gaps = 16/162 (9%)
Query: 76 HYKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPRKTDAPQLKDEY---RTYKILSGSE- 131
+Y + KK+GEGS+G ++ + NN IK ++ + ++DE T+ + + +E
Sbjct: 10 NYILEKKLGEGSYGDVYFCRDERNNKWSVIKLIHKEING--VRDETWRRETFALTALAEV 67
Query: 132 -GIPQAYYFGQEGLHNILVIDLLGPSLEDLFDWCGRR----FSIKTVVHVAIQMITLIEE 186
GI + Y +G +HN +V++ P L+DL + R FS T H+ Q++ ++++
Sbjct: 68 RGISRMYDYGATDIHNYIVME---PLLDDLTNIARRNGIKGFSKSTGFHILWQLVKILQD 124
Query: 187 LHDHDLIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRD 228
+H + + DIK DN +I N+ M+ L+DFG+++ ++D
Sbjct: 125 VHSFGIAHGDIKADNLMISGSNK--TFMLSLVDFGLSRSFKD 164
>SPCC576.15c [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 592
Score = 67.8 bits (164), Expect = 4e-11
Identities = 62/237 (26%), Positives = 105/237 (44%), Gaps = 26/237 (10%)
Query: 77 YKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPRKTDAPQLKDEYRTYK-----ILSGSE 131
+K G+ +GEGS+ + AIK ++ + K++Y + ILS
Sbjct: 99 FKFGEILGEGSYSTVLTATENSTKREYAIKVLDKRHIIKEKKEKYVNIEKEALCILSKHP 158
Query: 132 GIPQAYYFGQEGLHNILVIDLLGPSLEDLFDWCGR--RFSIKTVVHVAIQMITLIEELHD 189
G + +Y Q+ HN+ + L + E L D+ + RF+ + A ++ I+ +H
Sbjct: 159 GFIKLFYTFQDA-HNLYFVLSLARNGE-LLDYINKLGRFNEICAQYYAALIVDSIDYMHG 216
Query: 190 HDLIYRDIKPDNFLIGRPNQPDANM-VHLIDFGMAKL-------YRDPKTKQHIPYREKK 241
+I+RD+KP+N L+ D NM + DFG AK+ + + P +
Sbjct: 217 RGVIHRDLKPENILL------DDNMRTKITDFGSAKILNSSHGSHEEDTHHADKPQAHSR 270
Query: 242 SLSGTARYMSINTHLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKAANNKLKYEKI 298
S GTARY+S + D+ A G + F L G+ P+ A N L ++ I
Sbjct: 271 SFVGTARYVSPEVLSDKIAGTASDIWAFGCILFQMLAGKPPF---VAGNEYLTFQSI 324
>CE24636 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 330
Score = 67.8 bits (164), Expect = 4e-11
Identities = 77/322 (23%), Positives = 138/322 (41%), Gaps = 54/322 (16%)
Query: 77 YKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPRKTDAPQLKDEYRTYKILS----GSEG 132
Y I ++G+GSFG +F N+ A+K +PRK + + +L G +
Sbjct: 23 YTITGRVGQGSFGPIFSVSK--NHKDYALKIQPRKINGKPSTVQKEASLLLKLNPHGDKY 80
Query: 133 IPQAYYFGQEGLHNILVIDLLGPSLEDLFDWCGRRFSIK--TVVHVAIQMITLIEELHDH 190
P G+ +V++LLG SL+DL S+ T + IQ + ++++LHD
Sbjct: 81 FPTFKMAGENVKCAFIVMNLLGRSLKDLRLMSPNPDSLTPGTWSRIGIQCLYVLKQLHDG 140
Query: 191 DLIYRDIKPDNFLIGRPNQ-PDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTARY 249
+++ D+KP N+++G P + + +LIDF +A+ +
Sbjct: 141 AVVHGDVKPTNYVLGNPTDCLKSRIFYLIDFAIAQKF----------------------- 177
Query: 250 MSINTHLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKAANNKLKYEKIGEKKRSTNVYD 309
+GR DD+ +L ++ L+ LPW L+ N+L +K + + T ++D
Sbjct: 178 ------IGRV----DDLYSLLYMTAE-LKKPLPWTYLE--GNELILKK--KNAKLTELFD 222
Query: 310 LSQGLPVQFGRYLEIVRNLGFEETPDYEGYRKLLLSVLDELGQKLDGEYDWMKLN--GGR 367
+ L VQ ++ + + + P+Y + L V + G YDW N +
Sbjct: 223 NDEFLKVQ-----TMIESFSYRDFPNYGLLFETFLEVFLKSGSTWMSPYDWEGENMPSFQ 277
Query: 368 GWDLAINKKPNLHGYGHPTPPN 389
W NK +L + P N
Sbjct: 278 EWVKEANKPRHLFQWEVPEVVN 299
>CE02704 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 610
Score = 67.0 bits (162), Expect = 7e-11
Identities = 58/234 (24%), Positives = 104/234 (43%), Gaps = 28/234 (11%)
Query: 79 IGKKIGEGSFGVLFEGVNMINNVPVAIKFEPRKTDAP--------------QLKDEYRTY 124
+GK+ G FG + + + +K EP T+ P +L + Y+
Sbjct: 34 VGKQFATGGFGRIHTCTEEGKSQQMVMKIEP-STNGPLLTEVVVFNRILKKELIESYKKK 92
Query: 125 KILSGSEGIP----QAYYFGQEGLHNILVIDLLGPSLEDLFDWCGRRFSIKTVVHVAIQM 180
K +S G+P Y+ + ++I SLE + + G ++K + VA +
Sbjct: 93 KKISWI-GLPYLIANGYFTYESEKMRYMIIPKYATSLEAVRETNGGTLAMKDSLTVASCI 151
Query: 181 ITLIEELHDHDLIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREK 240
+ +E LH+ D + D+K N L+ + Q + L+DFG+A +T ++ +K
Sbjct: 152 LDALEYLHESDYAHADVKAANILLEK--QGVYSTAVLVDFGLAH-----RTTNNVDKPDK 204
Query: 241 KSL-SGTARYMSINTHLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKAANNKL 293
K +GT + S + H G S R D+E L + + G LPW L+++ K+
Sbjct: 205 KRAHNGTCIFTSTDAHRGNNPSFRGDIEILAYNLMMWATGTLPWMALESSPEKV 258
>At3g50530 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 601
Score = 65.9 bits (159), Expect = 2e-10
Identities = 57/217 (26%), Positives = 101/217 (46%), Gaps = 22/217 (10%)
Query: 77 YKIGKKIGEGSFGVLF-----EGVNMINNVPVAIKFEPRKTDAPQLKDEYRTYKIL---S 128
Y++G ++G G FG +G N V V + + + T A ++D R KIL S
Sbjct: 148 YELGDEVGRGHFGYTCAAKFKKGDNKGQQVAVKVIPKAKMTTAIAIEDVRREVKILRALS 207
Query: 129 GSEGIPQAYYFGQEGLHNILVIDLL--GPSLEDLFDWCGRRFSIKTVVHVAIQMITLIEE 186
G +P +Y E N+ ++ L G L D G +++ + V IQ++ ++
Sbjct: 208 GHNNLPH-FYDAYEDHDNVYIVMELCEGGELLDRILSRGGKYTEEDAKTVMIQILNVVAF 266
Query: 187 LHDHDLIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGT 246
H +++RD+KP+NFL ++ D + + IDFG++ R P + G+
Sbjct: 267 CHLQGVVHRDLKPENFLF--TSKEDTSQLKAIDFGLSDYVR--------PDERLNDIVGS 316
Query: 247 ARYMSINTHLGREQSRRDDMEALGHVFFYFLRGQLPW 283
A Y++ L R S D+ ++G + + L G P+
Sbjct: 317 AYYVAPEV-LHRSYSTEADIWSVGVIVYILLCGSRPF 352
>CE18967 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD and related
proteins
Length = 1101
Score = 65.5 bits (158), Expect = 2e-10
Identities = 58/241 (24%), Positives = 105/241 (43%), Gaps = 19/241 (7%)
Query: 83 IGEGSFGVLFEGVNMINNVPVAIKFEPRKTDAPQLKDEYRTYKILSGSEGIPQAYYFGQ- 141
+G G FG ++ G++ N VA+K + P +D R + P +F Q
Sbjct: 776 LGSGQFGTVYGGIHRRNGQHVAVKLIDKLKFPPNKEDLLRAEVQILEKVDHPGVVHFMQM 835
Query: 142 -EGLHNILVI--DLLGPSLEDLFDWCGRRFSIKTVVHVAIQMITLIEELHDHDLIYRDIK 198
E I V+ L G LE + R S +T + Q++ + LH ++++ D+K
Sbjct: 836 LETTDRIFVVMEKLKGDMLEMILSSEKGRLSERTTQFLVAQILEALRYLHHLNIVHCDLK 895
Query: 199 PDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTARYMSINTHLGR 258
P+N L+ + D V L DFG A++ + ++S+ GT Y++ +
Sbjct: 896 PENILLN--SNSDFPQVKLCDFGFARIIGEKSF--------RRSVVGTPAYLAPEVLRNK 945
Query: 259 EQSRRDDMEALGHVFFYFLRGQLPWQGLKAANNKLK-----YEKIGEKKRSTNVYDLSQG 313
+R DM ++G + + L G P+ + N++++ Y K+ S N + G
Sbjct: 946 GFNRSLDMWSVGVIVYVSLSGTFPFNEDEDINDQIQNAEFMYPPTPWKEISENAIEFING 1005
Query: 314 L 314
L
Sbjct: 1006 L 1006
>CE02376 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 321
Score = 65.5 bits (158), Expect = 2e-10
Identities = 51/203 (25%), Positives = 94/203 (46%), Gaps = 9/203 (4%)
Query: 73 VGLHYKIGKKIGEGSFGVLFEGVNMIN-NVPVAIKFEPRKTDAPQLKD-----EYRTYKI 126
+ YK+ K+G GSFG +++ + + NV +K + +D E +K
Sbjct: 32 IAKRYKLIHKVGSGSFGEVWQATDKLEGNVAKIVKIINKYVGGSGPRDILYDNEIEFFKY 91
Query: 127 LSGSEGIPQAYYFGQEGLHNILVIDLLGPSLEDLFDWCGRRFSIKTVVHVAIQMITLIEE 186
+ IP ++ N+LV+ G +L ++ FS+ ++ +A Q+ + +
Sbjct: 92 CHDAPNIPTLFHHFSHVGFNVLVMSEEGQNLREVAKRSPGSFSLNNLIRIAYQIGSTLCF 151
Query: 187 LHDHDLIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGT 246
+HD I+RD+K +N L+ N+ MV LIDFG A ++D + + + +
Sbjct: 152 IHDKSFIHRDLKAENVLVSLKNKV-CKMV-LIDFGNAVRFKDVNGNELPEFNDGFDYT-H 208
Query: 247 ARYMSINTHLGREQSRRDDMEAL 269
+ SIN LG ++ DD +L
Sbjct: 209 CTHKSINVLLGISHTQNDDWASL 231
>At3g19100 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 599
Score = 64.7 bits (156), Expect = 3e-10
Identities = 56/215 (26%), Positives = 104/215 (48%), Gaps = 20/215 (9%)
Query: 78 KIGKKIGEGSFGVLFEGV---NMINNVPVAIKFEPRK--TDAPQLKDEYRTYKIL---SG 129
++G++IG G FG + + VA+K P+ T A ++D R KIL SG
Sbjct: 145 ELGEEIGRGHFGYTCSAKFKKGELKDQEVAVKVIPKSKMTSAISIEDVRREVKILRALSG 204
Query: 130 SEGIPQAYYFGQEGLHNILVIDLLGPS-LEDLFDWCGRRFSIKTVVHVAIQMITLIEELH 188
+ + Q Y ++ + +V++L G L D G ++S V IQ++ ++ H
Sbjct: 205 HQNLVQFYDAFEDNANVYIVMELCGGGELLDRILARGGKYSEDDAKAVLIQILNVVAFCH 264
Query: 189 DHDLIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTAR 248
+++RD+KP+NFL ++ + +M+ +IDFG++ R P + G+A
Sbjct: 265 LQGVVHRDLKPENFLY--TSKEENSMLKVIDFGLSDFVR--------PDERLNDIVGSAY 314
Query: 249 YMSINTHLGREQSRRDDMEALGHVFFYFLRGQLPW 283
Y++ L R + D+ ++G + + L G P+
Sbjct: 315 YVAPEV-LHRSYTTEADVWSIGVIAYILLCGSRPF 348
>CE05552 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 303
Score = 64.3 bits (155), Expect = 4e-10
Identities = 45/164 (27%), Positives = 78/164 (47%), Gaps = 14/164 (8%)
Query: 77 YKIGKKIGEGSFGVLF----------EGVNMINNVPVAIKFEPRKTDAPQLKDEYRTYKI 126
YKI IG G G +F V +I +P+ + D PQ +E+
Sbjct: 12 YKIRFDIGPGRIGRIFAVLDQQDQSRSRVKVIKVLPMVAG--EQFLDDPQTYNEFDFLNH 69
Query: 127 LSGSEGIPQAYYFGQEGLHNILVIDLLGPSLEDLFDWCG-RRFSIKTVVHVAIQMITLIE 185
L G+ G+P Q G ++++D +LE C RR S ++ +A++++ ++E
Sbjct: 70 LRGTIGVPNIIQHFQVGRERVMMMDKYLATLEQFRTRCDDRRISDLNIIKIAVRLVNVLE 129
Query: 186 ELHDHDLIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDP 229
+H +I+RD+K N +I Q + N+V LID+G++ P
Sbjct: 130 AIHQKGVIHRDLKTTNVMIRSRGQSEVNLV-LIDYGLSTFNGTP 172
>CE24516 [OUT] KOG0595 Serine/threonine-protein kinase involved in autophagy
Length = 856
Score = 63.5 bits (153), Expect = 7e-10
Identities = 56/240 (23%), Positives = 101/240 (41%), Gaps = 23/240 (9%)
Query: 74 GLHYKIGKKIGEGSFGVLFEGVNMIN-NVPVAIKFEPRKTDAPQLKDEYRTYKILSGSEG 132
G Y +G G+F +++ G + +VPVAIK +K + + KIL
Sbjct: 6 GFEYSKRDLLGHGAFAIVYRGRYVDRTDVPVAIKAIAKKNISKSKNLLTKEIKILKELSS 65
Query: 133 IPQAYYFG-----QEGLHNILVIDLLGPSLEDLFDWCGRRFSIK--TVVHVAIQMITLIE 185
+ G + H LV++ DL D+ ++ ++ T+ H +Q+ +E
Sbjct: 66 LKHENLVGLLKCTETPTHVYLVMEFCNGG--DLADYLQQKTTLNEDTIQHFVVQIAHALE 123
Query: 186 ELHDHDLIYRDIKPDNFLI---GRPNQPDAN--MVHLIDFGMAKLYRDPKTKQHIPYREK 240
++ +++RD+KP N L+ R P ++ L DFG A+ D
Sbjct: 124 AINKKGIVHRDLKPQNILLCNNSRTQNPHFTDIVIKLADFGFARFLNDGVM--------A 175
Query: 241 KSLSGTARYMSINTHLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKAANNKLKYEKIGE 300
+L G+ YM+ + + + D+ ++G + F L G+ P+ K YEK E
Sbjct: 176 ATLCGSPMYMAPEVIMSMQYDAKADLWSIGTILFQCLTGKAPFVAQTPPQLKAYYEKTRE 235
>SPCC320.12c [D] KOG0580 Serine/threonine protein kinase
Length = 384
Score = 63.2 bits (152), Expect = 1e-09
Identities = 60/231 (25%), Positives = 105/231 (44%), Gaps = 26/231 (11%)
Query: 77 YKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPRKTDAPQLKDEY---RTYKILSG--SE 131
++IGK +G+G FG ++ VA+K K++ Q K E R +I S +
Sbjct: 118 FEIGKPLGKGKFGRVYLAKEKKTGFIVALK-TLHKSELVQSKIEKQVRREIEIQSNLRHK 176
Query: 132 GIPQAYYFGQEGLHNILVIDLLGPSLEDLFDWCGR--RFSIKTVVHVAIQMITLIEELHD 189
I + Y + L+++ G +L+ R RFS + QM + LH
Sbjct: 177 NILRLYGHFHDEKRIYLILEFAGRG--ELYQHLRRAKRFSEEVASKYIFQMANALSYLHK 234
Query: 190 HDLIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTARY 249
+I+RDIKP+N L+G + + L DFG + H P + +L GT Y
Sbjct: 235 KHVIHRDIKPENILLGIDGE-----IKLSDFGWS---------VHAPSNRRTTLCGTLDY 280
Query: 250 MSINTHLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKAANNKLKYEKIGE 300
+ G+E + + D+ +LG + + FL G P++ + + + Y++I +
Sbjct: 281 LPPEMVEGKEHTEKVDLWSLGVLTYEFLVGAPPFEDM--SGHSATYKRIAK 329
>YDR466w [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 898
Score = 62.8 bits (151), Expect = 1e-09
Identities = 65/238 (27%), Positives = 107/238 (44%), Gaps = 30/238 (12%)
Query: 81 KKIGEGSFGVLFEGVNMIN-NVPVAIKFEPRKTDAPQLKDEY-----RTYKILSGSE--G 132
+++G GS+ +F+ ++ + N AIK +K + K +Y T +L+ G
Sbjct: 15 EELGHGSYSTVFKALDKKSPNKIYAIKVCSKKHIIKEAKVKYVTIEKNTMNLLAQKHHAG 74
Query: 133 IPQAYYFGQEGLHNILVIDLL-GPSLEDLFDWCGRRFSIKTVVHVAIQMITLIEELHDHD 191
I + YY + + V+D G L L G I T H Q+I +E +H H
Sbjct: 75 IIKLYYTFHDEENLYFVLDFAPGGELLSLLHKMGTFNDIWTR-HFTAQLIDALEFIHSHG 133
Query: 192 LIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKK---------- 241
+I+RD+KP+N L+ R + + + DFG A + +
Sbjct: 134 IIHRDLKPENVLLDRDGR-----LMITDFGAAATIDPSLSGDSAKFNSDSNGSKDNQNCA 188
Query: 242 SLSGTARYMSINTHLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKAANNKLK-YEKI 298
S GTA Y+S L + D+ ALG + + F++GQ P++G N+LK +EKI
Sbjct: 189 SFVGTAEYVSPELLLYNQCGYGSDIWALGCMIYQFVQGQPPFRG----ENELKTFEKI 242
>CE07205 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 298
Score = 62.8 bits (151), Expect = 1e-09
Identities = 41/161 (25%), Positives = 81/161 (49%), Gaps = 14/161 (8%)
Query: 76 HYKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPRKTDAPQLKD---EYRTYKILSGSEG 132
HY + K +G+G +G + + NN K ++ + + K E ++G G
Sbjct: 9 HYTLEKLLGKGMYGEVHLCKDDRNNEARVAKLILKEHNGIRDKSWAHETLALNAVAGVNG 68
Query: 133 IPQAYYFGQEGLHNILVIDLLGPSLEDLFDWC---GRRFSIKTVVHVAIQMITLIEELHD 189
+P+ + G HN +V+DLL LE + C ++F+ T + Q++ +++++H
Sbjct: 69 VPRMFATGSTDYHNWIVMDLLSDDLEVII--CRNENKKFAKATGYQILWQVVKILKDIHS 126
Query: 190 HDLIYRDIKPDNFLIGRPNQPDANMVH--LIDFGMAKLYRD 228
+++ DIKP+N ++ +NM L+DFG A+ ++D
Sbjct: 127 KGIVHGDIKPNNLMVSH----SSNMFQLVLVDFGCARRFKD 163
>CE07204 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 298
Score = 62.8 bits (151), Expect = 1e-09
Identities = 66/286 (23%), Positives = 124/286 (43%), Gaps = 26/286 (9%)
Query: 76 HYKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPRKTDAPQ---LKDEYRTYKILSGSEG 132
+Y +GK +G GSFG + + +N +K ++ D + + E T LS G
Sbjct: 9 NYTLGKVLGRGSFGSVQLAQDKRSNEMRVMKLIRKERDGHRDETWRRETFTLTALSDVSG 68
Query: 133 IPQAYYFGQEGLHNILVIDLLGPSLEDLFDWCGRR----FSIKTVVHVAIQMITLIEELH 188
+ + + +G HN +V++ L +DL R FS T + Q++ +++++H
Sbjct: 69 VTKMFEYGSTETHNWIVMEQLS---DDLITIVRRNETKMFSKPTSYQIMWQLVKILQDIH 125
Query: 189 DHDLIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTAR 248
+++ DIK DN ++ N+ + L+D+G++ ++D + P +
Sbjct: 126 AIGIVHTDIKADNLMVSYKNR--VRKLVLVDYGLSCWFKD-HNQNRTPPAPFDNRCMHLI 182
Query: 249 YMSINTHLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKA---ANNKLKYEKIGEKKRST 305
+ T G +D+ + ++ L +PW+ ++A K K+ K KK
Sbjct: 183 HTPAKTATGHPHMEAEDLVQVAYL-SCSLHQFMPWKDVEAPKMTKMKKKFAK-NPKKYLG 240
Query: 306 NVYDLSQGLPVQFGRYLEIVRNLGFEETPDYEGYRKLLLSVLDELG 351
N DL + + + + G E PDYEG LL + LG
Sbjct: 241 NHQDLKPIIK------MLVKQKHGVE--PDYEGILDLLQDMFGSLG 278
>At3g56760 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 577
Score = 62.8 bits (151), Expect = 1e-09
Identities = 56/217 (25%), Positives = 101/217 (45%), Gaps = 20/217 (9%)
Query: 76 HYKIGKKIGEGSFGVLFEGVNM---INNVPVAIKFEPRK--TDAPQLKDEYRTYKIL--- 127
HY+I ++G G FG + VA+K P+ T A ++D R KIL
Sbjct: 123 HYEIDGEVGRGHFGYTCSAKGKKGSLKGQDVAVKVIPKSKMTTAIAIEDVRREVKILRAL 182
Query: 128 SGSEGIPQAYYFGQEGLHNILVIDLL-GPSLEDLFDWCGRRFSIKTVVHVAIQMITLIEE 186
+G + + Q Y ++ + +V++L G L D G ++S V IQ+++++
Sbjct: 183 TGHKNLVQFYDAFEDDENVYIVMELCQGGELLDKILQRGGKYSEVDAKKVMIQILSVVAY 242
Query: 187 LHDHDLIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGT 246
H +++RD+KP+NFL + +++ + IDFG++ R P + G+
Sbjct: 243 CHLQGVVHRDLKPENFLF--TTKDESSPLKAIDFGLSDYVR--------PDERLNDIVGS 292
Query: 247 ARYMSINTHLGREQSRRDDMEALGHVFFYFLRGQLPW 283
A Y++ L R DM ++G + + L G P+
Sbjct: 293 AYYVAPEV-LHRTYGTEADMWSIGVIAYILLCGSRPF 328
>SPBC18H10.15 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 398
Score = 62.4 bits (150), Expect = 2e-09
Identities = 64/267 (23%), Positives = 111/267 (40%), Gaps = 38/267 (14%)
Query: 77 YKIGKKIGEGSFGVLFEGVNMINNVPVA---IKFEPRKTDAP--QLKDEYRTYKILSGSE 131
Y+I +KI EGS+G+++ G++ N VA IKF+P P L++ I +
Sbjct: 74 YEILEKIEEGSYGIVYRGLDKSTNTLVALKKIKFDPNGIGFPITSLREIESLSSIRHDNI 133
Query: 132 GIPQAYYFGQEGLHNILVIDLLGPSLEDLFDWCGRRFSIKTVVHVAIQMITLIEELHDHD 191
+ G++ LV++ + L+ L D F V + +Q++ +H H
Sbjct: 134 VELEKVVVGKDLKDVYLVMEFMEHDLKTLLDNMPEDFLQSEVKTLMLQLLAATAFMHHHW 193
Query: 192 LIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTK-----QHIPYREKKSLSGT 246
++RD+KP N L+ + + L DFG+A+ +PK+ + YR + L G
Sbjct: 194 YLHRDLKPSNLLMNNTGE-----IKLADFGLARPVSEPKSSLTRLVVTLWYRAPELLLGA 248
Query: 247 ARY---------------MSINTHLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKAANN 291
Y M T L +S D + + ++ Y R + P L N
Sbjct: 249 PSYGKEIDMWSIGCIFAEMITRTPLFSGKSELDQLYKIFNLLGYPTREEWPQYFLLPYAN 308
Query: 292 KLKYEKIGEKKR--------STNVYDL 310
K+K+ + + + N YDL
Sbjct: 309 KIKHPTVPTHSKIRTSIPNLTGNAYDL 335
>At4g21940 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 554
Score = 62.4 bits (150), Expect = 2e-09
Identities = 58/216 (26%), Positives = 101/216 (45%), Gaps = 24/216 (11%)
Query: 77 YKIGKKIGEGSFGVLFEGVNMINNVPVAIKFE-----PRKTDAPQLKDEYRTYKILSGSE 131
Y +GK++G G FG+ + A K RK D +K E + + LSG E
Sbjct: 102 YTLGKELGRGQFGITYTCKENSTGNTYACKSILKRKLTRKQDIDDVKREIQIMQYLSGQE 161
Query: 132 GIPQ--AYYFGQEGLHNILVIDLLGPSLEDLFDW--CGRRFSIKTVVHVAIQMITLIEEL 187
I + Y ++ +H LV++L G S +LFD +S K V ++ +++
Sbjct: 162 NIVEIKGAYEDRQSIH--LVMELCGGS--ELFDRIIAQGHYSEKAAAGVIRSVLNVVQIC 217
Query: 188 HDHDLIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTA 247
H +I+RD+KP+NFL+ + + M+ DFG++ + K YR+ + G+A
Sbjct: 218 HFMGVIHRDLKPENFLLA--STDENAMLKATDFGLSVFIEEGKV-----YRD---IVGSA 267
Query: 248 RYMSINTHLGREQSRRDDMEALGHVFFYFLRGQLPW 283
Y++ L R + D+ + G + + L G P+
Sbjct: 268 YYVAPEV-LRRSYGKEIDIWSAGIILYILLCGVPPF 302
>At1g09000 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 666
Score = 62.4 bits (150), Expect = 2e-09
Identities = 57/219 (26%), Positives = 100/219 (45%), Gaps = 21/219 (9%)
Query: 75 LHYKIGKKIGEGSFGVLFEGVNM-------INNVPVAIKFEPR-KTDA--PQLKDEYRTY 124
+ ++ G+ IG G+FG ++ G+N+ + V +A F + KT A +L++E +
Sbjct: 67 ISWRKGQLIGRGAFGTVYMGMNLDSGELLAVKQVLIAANFASKEKTQAHIQELEEEVKLL 126
Query: 125 KILSGSEGIPQAYYFGQEGLHNILVIDLLGPSLEDLFDWCGRRFSIKTVVHVAIQMITLI 184
K LS + ++ NIL+ + G S+ L + G F V Q++ +
Sbjct: 127 KNLSHPNIVRYLGTVREDDTLNILLEFVPGGSISSLLEKFGP-FPESVVRTYTRQLLLGL 185
Query: 185 EELHDHDLIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLS 244
E LH+H +++RDIK N L+ + + L DFG +K + T KS+
Sbjct: 186 EYLHNHAIMHRDIKGANILV-----DNKGCIKLADFGASKQVAELAT-----MTGAKSMK 235
Query: 245 GTARYMSINTHLGREQSRRDDMEALGHVFFYFLRGQLPW 283
GT +M+ L S D+ ++G + G+ PW
Sbjct: 236 GTPYWMAPEVILQTGHSFSADIWSVGCTVIEMVTGKAPW 274
>At1g54960 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 585
Score = 62.0 bits (149), Expect = 2e-09
Identities = 56/219 (25%), Positives = 99/219 (44%), Gaps = 21/219 (9%)
Query: 75 LHYKIGKKIGEGSFGVLFEGVNMINNVPVAIK--------FEPRKTDA--PQLKDEYRTY 124
+ ++ G+ IG G+FG ++ G+N+ + +A+K KT A +L++E +
Sbjct: 66 IRWRKGQLIGRGAFGTVYMGMNLDSGELLAVKQVLITSNCASKEKTQAHIQELEEEVKLL 125
Query: 125 KILSGSEGIPQAYYFGQEGLHNILVIDLLGPSLEDLFDWCGRRFSIKTVVHVAIQMITLI 184
K LS + ++ NIL+ + G S+ L + G F V Q++ +
Sbjct: 126 KNLSHPNIVRYLGTVREDETLNILLEFVPGGSISSLLEKFGA-FPESVVRTYTNQLLLGL 184
Query: 185 EELHDHDLIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLS 244
E LH+H +++RDIK N L+ + + L DFG +K + T KS+
Sbjct: 185 EYLHNHAIMHRDIKGANILV-----DNQGCIKLADFGASKQVAELAT-----ISGAKSMK 234
Query: 245 GTARYMSINTHLGREQSRRDDMEALGHVFFYFLRGQLPW 283
GT +M+ L S D+ ++G + G+ PW
Sbjct: 235 GTPYWMAPEVILQTGHSFSADIWSVGCTVIEMVTGKAPW 273
>7302202 [D] KOG1166 Mitotic checkpoint serine/threonine protein kinase
Length = 1460
Score = 62.0 bits (149), Expect = 2e-09
Identities = 56/218 (25%), Positives = 104/218 (47%), Gaps = 24/218 (11%)
Query: 77 YKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPRKTDAPQLKDEYRTYKILSGSEGIPQA 136
+++ K IG+G++G ++ G ++ + VA+K E R T+ + + L+ + IP
Sbjct: 1175 FEVSKMIGKGAYGSVYVGKHLKSGKKVALKQE-RPTNYWEFYICLEIHSRLTSEQMIPSY 1233
Query: 137 YY--FGQEGLHNILVIDLLGPSLEDLFDWCGRRFSIKT-------VVHVAIQMITLIEEL 187
+ + G ++ + I L C + S+ V+H++ QM+ +++ L
Sbjct: 1234 AHIDYALVGNNSSVYISEFS-DYGSLIGVCNKVKSVTNRNMDEYVVMHLSCQMLDIVDHL 1292
Query: 188 HDHDLIYRDIKPDNFLIGRPNQPDANMV--HLIDFGMA---KLYRDPKTKQHIPYREKKS 242
H +I+ DIKPDNFL+ +P D N V LIDFG++ KL+ D +T ++ + +
Sbjct: 1293 HAMGIIHADIKPDNFLLMKPICADPNEVSLQLIDFGVSIDMKLFPDNQTFNYVHHDD--- 1349
Query: 243 LSGTARYMSINTHLGREQSRRDDMEALGHVFFYFLRGQ 280
+ I GR + + D+ L V L G+
Sbjct: 1350 -----LFKCIEMRTGRPWTYQLDLYGLVSVMHVLLFGR 1382
>CE05507 [T] KOG0603 Ribosomal protein S6 kinase
Length = 785
Score = 61.6 bits (148), Expect = 3e-09
Identities = 56/232 (24%), Positives = 110/232 (47%), Gaps = 30/232 (12%)
Query: 77 YKIGKK----IGEGSFGVLFEGVNMINNVPVAIKFEPRKTDAPQLKDEYRTYKILSGSEG 132
YK+ K +G+G+F V+ +++ A+K +K A Q + E R +++ G
Sbjct: 378 YKLDKSDAGLLGKGAFSVVRRCERVVDGAQFAVKIVSQKF-ASQAQREARILEMVQGHPN 436
Query: 133 IPQAYYFGQEGLHNILVIDLLGPSLEDLFDWCGR--RFSIKTVVHVAIQMITLIEELHDH 190
I Q + + LH LV+++L + +L + + RF+ + Q+++ ++ LHD
Sbjct: 437 IVQLHDVHSDPLHFYLVMEILTGN--ELLERIRKLERFTESEAADIMRQLVSAVKYLHDK 494
Query: 191 DLIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSG----- 245
+++RD+KP+N L + + + L+DFG A+L + +Q + + + G
Sbjct: 495 RIVHRDLKPENILF--ESIDSSARLRLVDFGFARLLPNSMEQQLKSVQVLRKMYGLIAHN 552
Query: 246 ----------TARYMSINT-HLGREQ---SRRDDMEALGHVFFYFLRGQLPW 283
T +Y + +G Q + + D+ +LG V F L GQ+P+
Sbjct: 553 HSLHSETPCFTLQYAAPEVLDVGDSQPEYNEQCDLWSLGVVLFTMLSGQVPF 604
>CE03889 [T] KOG1345 Serine/threonine kinase
Length = 356
Score = 61.6 bits (148), Expect = 3e-09
Identities = 61/225 (27%), Positives = 101/225 (44%), Gaps = 35/225 (15%)
Query: 77 YKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPRKTDAPQLK--DEYRTYK--------- 125
Y + K++G G FG + + + +AIKF PR PQ K D R Y
Sbjct: 13 YTVNKQLGTGRFGFIKLAEHKQSKQRIAIKFFPR----PQTKQADFVREYNYSFFLSPHQ 68
Query: 126 -ILSGSEGIPQ-----AYYFGQEGLHNILVIDLLGPSLEDLFDWCGRRFSIKTVVHVAIQ 179
I+ EG+ Q AY+F QE + + + + + G + V A+
Sbjct: 69 NIIDTYEGMFQSSDDTAYFFVQEFCPRASLREAV-----EATNQAGIGEANTKKVFAAV- 122
Query: 180 MITLIEELHDHDLIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYRE 239
++ IE +HD +L++R++K +N LI N D + V + DFG+ + K + Y E
Sbjct: 123 -LSAIEFMHDENLVHRNLKAENILIFDAN--DYSKVKVTDFGLTR-----KVDTTVKYLE 174
Query: 240 KKSLSGTARYMSINTHLGREQSRRDDMEALGHVFFYFLRGQLPWQ 284
+ A + ++ D+ ALG +FFY ++G+ PWQ
Sbjct: 175 YVNNYHAAELCDTVVNEKLVVNKSTDIWALGIIFFYCMKGKFPWQ 219
>Hs6031180 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and related
serine/threonine protein kinases
Length = 1558
Score = 61.2 bits (147), Expect = 4e-09
Identities = 61/219 (27%), Positives = 99/219 (44%), Gaps = 20/219 (9%)
Query: 73 VGLHYKIGKKIGEGSFGVLFEGVNMINNVPVAIK---FEPRKTDAPQLKDEYRTYKILSG 129
V ++ G KIGEG +G ++ +++ +A+K F+P D +K+ KI G
Sbjct: 1289 VTFKWQRGNKIGEGQYGKVYTCISVDTGELMAMKEIRFQPN--DHKTIKETADELKIFEG 1346
Query: 130 SEGIPQAYYFGQEGLHNILVIDLLGPSLEDLFDWCGRRFSIKTVVHVAIQMITL-IEELH 188
+ YFG E LH + + E + R + V+ + + IT+ I LH
Sbjct: 1347 IKHPNLVRYFGVE-LHREEMYIFMEYCDEGTLEEVSRLGLQEHVIRLYSKQITIAINVLH 1405
Query: 189 DHDLIYRDIKPDNFLIGRPNQPDANMVHLIDFGMA-KLYRDPKTKQHIPYREKKSLSGTA 247
+H +++RDIK N + + ++ L DFG + KL + +T E S GTA
Sbjct: 1406 EHGIVHRDIKGANIFL-----TSSGLIKLGDFGCSVKLKNNAQTMP----GEVNSTLGTA 1456
Query: 248 RYMS---INTHLGREQSRRDDMEALGHVFFYFLRGQLPW 283
YM+ I G R D+ +LG V + G+ PW
Sbjct: 1457 AYMAPEVITRAKGEGHGRAADIWSLGCVVIEMVTGKRPW 1495
>Hs5803088 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and related
serine/threonine protein kinases
Length = 1607
Score = 61.2 bits (147), Expect = 4e-09
Identities = 61/219 (27%), Positives = 99/219 (44%), Gaps = 20/219 (9%)
Query: 73 VGLHYKIGKKIGEGSFGVLFEGVNMINNVPVAIK---FEPRKTDAPQLKDEYRTYKILSG 129
V ++ G KIGEG +G ++ +++ +A+K F+P D +K+ KI G
Sbjct: 1338 VTFKWQRGNKIGEGQYGKVYTCISVDTGELMAMKEIRFQPN--DHKTIKETADELKIFEG 1395
Query: 130 SEGIPQAYYFGQEGLHNILVIDLLGPSLEDLFDWCGRRFSIKTVVHVAIQMITL-IEELH 188
+ YFG E LH + + E + R + V+ + + IT+ I LH
Sbjct: 1396 IKHPNLVRYFGVE-LHREEMYIFMEYCDEGTLEEVSRLGLQEHVIRLYSKQITIAINVLH 1454
Query: 189 DHDLIYRDIKPDNFLIGRPNQPDANMVHLIDFGMA-KLYRDPKTKQHIPYREKKSLSGTA 247
+H +++RDIK N + + ++ L DFG + KL + +T E S GTA
Sbjct: 1455 EHGIVHRDIKGANIFL-----TSSGLIKLGDFGCSVKLKNNAQTMP----GEVNSTLGTA 1505
Query: 248 RYMS---INTHLGREQSRRDDMEALGHVFFYFLRGQLPW 283
YM+ I G R D+ +LG V + G+ PW
Sbjct: 1506 AYMAPEVITRAKGEGHGRAADIWSLGCVVIEMVTGKRPW 1544
>CE25557 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 511
Score = 61.2 bits (147), Expect = 4e-09
Identities = 68/271 (25%), Positives = 111/271 (40%), Gaps = 44/271 (16%)
Query: 77 YKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPRKTDAPQ-LKDEYRTYKILSGSEGIPQ 135
YK+ KKI EG FG +F+ V + A+K E + +K E L + P
Sbjct: 43 YKLVKKIDEGGFGQVFK-VTKDDKTFYAMKLESNFLEGGSAIKLELNVLSQLPKNSVFPA 101
Query: 136 AYYFGQEGLHNILVIDLLGPSLEDLFDWCGRR--FSIKTVVHVAIQMITLIEELHDHDLI 193
G+ + LV++LLG +L+ L +S T V IQ + I+ +HD +
Sbjct: 102 LVCGGRRARYQFLVLELLGDNLKVLKSQSTNPEVWSDGTWSRVGIQCLFAIKVMHDAGFV 161
Query: 194 YRDIKPDNFLIG--RPNQPDANMVHLIDFGMAKLY--RDPKTKQHIPYREKKSLSGTARY 249
+RDIKP NF IG ++ + + L DFG+A+ + + P+ + K+ S +
Sbjct: 162 HRDIKPSNFAIGFSATSEIRSRRILLFDFGLARKFVRKLPQASVSVKKDVSKAKSALLKN 221
Query: 250 MSINTHLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKAANNKLKYEKIGEKKRSTNVYD 309
S + + LRG+ P ++ + +K +K T D
Sbjct: 222 SSTTKAVAK------------------LRGKPPTHRIR---DPMKMKKSAGSAAKTKNKD 260
Query: 310 LSQGLPVQFGRYLEIVRNLGFEETPDYEGYR 340
SQ EE P++EGY+
Sbjct: 261 PSQ---------------RAMEEIPEHEGYK 276
>CE08836 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 517
Score = 61.2 bits (147), Expect = 4e-09
Identities = 52/170 (30%), Positives = 81/170 (47%), Gaps = 7/170 (4%)
Query: 77 YKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPR-KTDAPQLKDEYRTYKILSGSEGIPQ 135
Y+I KI EG FG +F+ V + A+K E + +K E L + P+
Sbjct: 27 YEIVSKIDEGGFGQVFK-VTKDHKTFYAMKLESNFQVGGSAIKLEINVLSQLPKNTVFPE 85
Query: 136 AYYFGQEGLHNILVIDLLGPSLEDLFDWCGRR--FSIKTVVHVAIQMITLIEELHDHDLI 193
G+ ++ LV++LLG +L+ L FS T + IQ + ++ +HD +
Sbjct: 86 LICGGKRPRYHFLVLELLGDNLKALKAQSPNPSVFSDGTWSRIGIQCLYAMKMMHDSGFV 145
Query: 194 YRDIKPDNFLIG--RPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKK 241
+RDIKP NF IG ++ + V L DFG+A+ + K K P KK
Sbjct: 146 HRDIKPSNFAIGYSTASESRSRRVLLFDFGLARKF-VKKEKNLAPIVTKK 194
>At2g17890 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 571
Score = 61.2 bits (147), Expect = 4e-09
Identities = 52/214 (24%), Positives = 98/214 (45%), Gaps = 18/214 (8%)
Query: 77 YKIGKKIGEGSFGVLFEGVNMINNVPVAIK-FEPRKTDAP----QLKDEYRTYKILSGSE 131
Y IGK +G G FG + + VA+K + K P +K E + + L+G E
Sbjct: 108 YTIGKLLGHGQFGYTYVATDKKTGDRVAVKKIDKAKMTIPIAVEDVKREVKILQALTGHE 167
Query: 132 GIPQAYYFGQEGLHNILVIDLL--GPSLEDLFDWCGRRFSIKTVVHVAIQMITLIEELHD 189
+ + Y ++ +V++L G L+ + R+S + V QM+ + E H
Sbjct: 168 NVVRFYNAFEDKNSVYIVMELCEGGELLDRILARKDSRYSERDAAVVVRQMLKVAAECHL 227
Query: 190 HDLIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTARY 249
L++RD+KP+NFL + + + + DFG++ + P ++ + G+A Y
Sbjct: 228 RGLVHRDMKPENFLF--KSTEEDSPLKATDFGLSDFIK--------PGKKFHDIVGSAYY 277
Query: 250 MSINTHLGREQSRRDDMEALGHVFFYFLRGQLPW 283
++ L R D+ ++G + + L G+ P+
Sbjct: 278 VAPEV-LKRRSGPESDVWSIGVISYILLCGRRPF 310
>YJL095w [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 1478
Score = 60.8 bits (146), Expect = 5e-09
Identities = 61/269 (22%), Positives = 119/269 (43%), Gaps = 31/269 (11%)
Query: 80 GKKIGEGSFGVLFEGVNMINNVPVAIKF----------EPRKTDAPQLKDEYRTYKILSG 129
G+ IG+GSFG ++ +N+ +A+K E + L+ E T K L
Sbjct: 1178 GEMIGKGSFGAVYLCLNVTTGEMMAVKQVEVPKYSSQNEAILSTVEALRSEVSTLKDLDH 1237
Query: 130 SEGIPQAYYFGQEGLHNILVIDLLGPSLEDLFDWCGRRFSIKTVVHVAIQMITLIEELHD 189
+ + + ++++ + + G S+ L GR F + H+ Q++ + LH
Sbjct: 1238 LNIVQYLGFENKNNIYSLFLEYVAGGSVGSLIRMYGR-FDEPLIKHLTTQVLKGLAYLHS 1296
Query: 190 HDLIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTARY 249
+++RD+K DN L+ + + + DFG+++ +D I ++ GT +
Sbjct: 1297 KGILHRDMKADNLLLDQD-----GICKISDFGISRKSKD------IYSNSDMTMRGTVFW 1345
Query: 250 MS---INTHLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKAANNKLKYEKIGEKKRSTN 306
M+ ++T G S + D+ +LG + G+ PW L+ KIG+ K +
Sbjct: 1346 MAPEMVDTKQG--YSAKVDIWSLGCIVLEMFAGKRPWSNLEVVAAMF---KIGKSKSAPP 1400
Query: 307 VYDLSQGLPVQFGR-YLEIVRNLGFEETP 334
+ + + L Q GR +L+ + E+ P
Sbjct: 1401 IPEDTLPLISQIGRNFLDACFEINPEKRP 1429
>SPACUNK12.02c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 335
Score = 60.5 bits (145), Expect = 6e-09
Identities = 54/214 (25%), Positives = 101/214 (46%), Gaps = 18/214 (8%)
Query: 77 YKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPRKTDAPQ---LKDEYRTYKILSGSEGI 133
Y++G+ +G G++ + E V++ N A K +K + +K+E K +S
Sbjct: 31 YRVGRVLGGGTYATVREAVHIETNKMYAAKIMNKKMMEKKQDFVKNEIAILKRVSYEH-- 88
Query: 134 PQAYYFGQ--EGLHNILVIDLLGPSLEDLFDWCGRRFSIKTVVHVAIQMITL--IEELHD 189
P + E ++N+ +I L E LFD + S A+ T ++ LHD
Sbjct: 89 PNILHLVDFFETVNNLYLITELATGGE-LFDRICAKGSFYEADAAALMRTTTSAVKYLHD 147
Query: 190 HDLIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTARY 249
+ +++RD+KP+N L+ R P+++++ + DFG++ Y D + Y + GT Y
Sbjct: 148 NGIVHRDLKPEN-LLYRSKDPNSDLL-IADFGLSHFYEDSQ------YYMLMTACGTPEY 199
Query: 250 MSINTHLGREQSRRDDMEALGHVFFYFLRGQLPW 283
M+ + DM A+G + ++ L G P+
Sbjct: 200 MAPEVFRRTGYGKPVDMWAIGVITYFLLSGYTPF 233
>Hs4505811 [T] KOG0583 Serine/threonine protein kinase
Length = 313
Score = 60.5 bits (145), Expect = 6e-09
Identities = 44/163 (26%), Positives = 85/163 (51%), Gaps = 16/163 (9%)
Query: 77 YKIGKKIGEGSFGVLFEGVNMINNVPVAIKF--EPRKTDAPQLKDEYRT-------YKIL 127
Y++G +G G FG ++ G+ + +N+PVAIK + R +D +L + R K+
Sbjct: 38 YQVGPLLGSGGFGSVYSGIRVSDNLPVAIKHVEKDRISDWGELPNGTRVPMEVVLLKKVS 97
Query: 128 SGSEGIPQAYYFGQEGLHNILVIDLLGPSLEDLFDWCGRRFSIKTVVHVAI--QMITLIE 185
SG G+ + + + +L+++ P ++DLFD+ R +++ + + Q++ +
Sbjct: 98 SGFSGVIRLLDWFERPDSFVLILERPEP-VQDLFDFITERGALQEELARSFFWQVLEAVR 156
Query: 186 ELHDHDLIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRD 228
H+ +++RDIK +N LI + + LIDFG L +D
Sbjct: 157 HCHNCGVLHRDIKDENILI----DLNRGELKLIDFGSGALLKD 195
>At5g24430 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 594
Score = 60.5 bits (145), Expect = 6e-09
Identities = 58/219 (26%), Positives = 99/219 (44%), Gaps = 22/219 (10%)
Query: 77 YKIGKKIGEGSFGVLF-----EGVNMINNVPVAIKFEPRKTDAPQLKDEYRTYKILSGSE 131
Y++GK++G G FG +G V V I + + T ++D R K+L
Sbjct: 143 YELGKEVGRGHFGHTCWAKAKKGKMKNQTVAVKIISKAKMTSTLSIEDVRREVKLLKALS 202
Query: 132 GIPQA--YYFGQEGLHNILVIDLL--GPSLEDLFDWCGRRFSIKTVVHVAIQMITLIEEL 187
G +Y E N+ V+ L G L D G R+ + +Q+++
Sbjct: 203 GHRHMVKFYDVYEDADNVFVVMELCEGGELLDRILARGGRYPEVDAKRILVQILSATAFF 262
Query: 188 HDHDLIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREK-KSLSGT 246
H +++RD+KP+NFL N+ DA ++ +IDFG++ R Y ++ + G+
Sbjct: 263 HLQGVVHRDLKPENFLFTSRNE-DA-ILKVIDFGLSDFIR---------YDQRLNDVVGS 311
Query: 247 ARYMSINTHLGREQSRRDDMEALGHVFFYFLRGQLPWQG 285
A Y++ L R S DM ++G + + L G P+ G
Sbjct: 312 AYYVAPEV-LHRSYSTEADMWSIGVISYILLCGSRPFYG 349
>At4g36070 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 536
Score = 60.5 bits (145), Expect = 6e-09
Identities = 54/213 (25%), Positives = 99/213 (46%), Gaps = 19/213 (8%)
Query: 77 YKIGKKIGEGSFGVLFEGVNMINNVPVAIKF--EPRKTDAPQLKDEYRTYKILS---GSE 131
Y IGK +G G FG + + N VA+K + + T +++D R KIL G E
Sbjct: 71 YTIGKLLGHGQFGFTYVATDNNNGNRVAVKRIDKAKMTQPIEVEDVKREVKILQALGGHE 130
Query: 132 GIPQAYYFGQEGLHNILVIDLL-GPSLEDLFDWCGRRFSIKTVVHVAIQMITLIEELHDH 190
+ + ++ + +V++L G L D R++ K V QM+ + E H
Sbjct: 131 NVVGFHNAFEDKTYIYIVMELCDGGELLDRI--LANRYTEKDAAVVVRQMLKVAAECHLR 188
Query: 191 DLIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTARYM 250
L++RD+KP+NFL + + + + DFG++ + P + + + G+A Y+
Sbjct: 189 GLVHRDMKPENFLF--KSTEEGSSLKATDFGLSDFIK--------PGVKFQDIVGSAYYV 238
Query: 251 SINTHLGREQSRRDDMEALGHVFFYFLRGQLPW 283
+ L R D+ ++G + + L G+ P+
Sbjct: 239 APEV-LKRRSGPESDVWSIGVITYILLCGRRPF 270
>At2g41140 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 576
Score = 60.5 bits (145), Expect = 6e-09
Identities = 53/217 (24%), Positives = 100/217 (45%), Gaps = 20/217 (9%)
Query: 76 HYKIGKKIGEGSFGVLFEGVNM---INNVPVAIKFEPRK--TDAPQLKDEYRTYKIL--- 127
HY+I ++G G FG + VA+K P+ T A ++D R K+L
Sbjct: 122 HYEIDGEVGRGHFGYTCSAKGKKGSLKGQEVAVKVIPKSKMTTAIAIEDVSREVKMLRAL 181
Query: 128 SGSEGIPQAYYFGQEGLHNILVIDLL-GPSLEDLFDWCGRRFSIKTVVHVAIQMITLIEE 186
+G + + Q Y ++ + +V++L G L D G ++S V +Q+++++
Sbjct: 182 TGHKNLVQFYDAFEDDENVYIVMELCKGGELLDKILQRGGKYSEDDAKKVMVQILSVVAY 241
Query: 187 LHDHDLIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGT 246
H +++RD+KP+NFL + + + + IDFG++ + P + G+
Sbjct: 242 CHLQGVVHRDLKPENFLFS--TKDETSPLKAIDFGLSDYVK--------PDERLNDIVGS 291
Query: 247 ARYMSINTHLGREQSRRDDMEALGHVFFYFLRGQLPW 283
A Y++ L R DM ++G + + L G P+
Sbjct: 292 AYYVAPEV-LHRTYGTEADMWSIGVIAYILLCGSRPF 327
>Hs4507831 [OUT] KOG0595 Serine/threonine-protein kinase involved in autophagy
Length = 1050
Score = 60.1 bits (144), Expect = 8e-09
Identities = 59/224 (26%), Positives = 100/224 (44%), Gaps = 19/224 (8%)
Query: 83 IGEGSFGVLFEGVNMI-NNVPVAIKFEPRKTDAPQLKDEYRTYKILSG--SEGIPQAYYF 139
IG G+F V+F+G + +++ VA+K +K A + KIL E I Y F
Sbjct: 22 IGHGAFAVVFKGRHREKHDLEVAVKCINKKNLAKSQTLLGKEIKILKELKHENIVALYDF 81
Query: 140 GQEGLHNILVIDLLGPSLEDLFDWCG--RRFSIKTVVHVAIQMITLIEELHDHDLIYRDI 197
+ LV++ DL D+ R S T+ Q+ + LH +I+RD+
Sbjct: 82 QEMANSVYLVMEYCNGG--DLADYLHAMRTLSEDTIRLFLQQIAGAMRLLHSKGIIHRDL 139
Query: 198 KPDNFLI----GRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTARYMSIN 253
KP N L+ GR P++ V + DFG A+ + +L G+ YM+
Sbjct: 140 KPQNILLSNPAGRRANPNSIRVKIADFGFARYLQSNMMAA--------TLCGSPMYMAPE 191
Query: 254 THLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKAANNKLKYEK 297
+ + + D+ ++G + + L G+ P+Q + +L YEK
Sbjct: 192 VIMSQHYDGKADLWSIGTIVYQCLTGKAPFQASSPQDLRLFYEK 235
>CE18169 [T] KOG0603 Ribosomal protein S6 kinase
Length = 797
Score = 60.1 bits (144), Expect = 8e-09
Identities = 58/218 (26%), Positives = 92/218 (41%), Gaps = 24/218 (11%)
Query: 77 YKIGKKIGEGSFGVLF-------EGVNMINNVPVAIKFEPRKTDAPQLKDEYRTYKILSG 129
+++ K +G+GSFG +F + + V K + D + K E +S
Sbjct: 104 FELLKVLGQGSFGKVFLVRKVRGRDSGHVYAMKVLKKATLKVRDRQRTKLERNILAHISH 163
Query: 130 SEGIPQAYYFGQEGLHNILVIDLLGPSLEDLFDWCGRR--FSIKTVVHVAIQMITLIEEL 187
+ Y F EG L++D L DLF + F+ V ++ +E L
Sbjct: 164 PFIVKLHYAFQTEG-KLYLILDFLRGG--DLFTRLSKEVMFTEDDVKFYLAELTLALEHL 220
Query: 188 HDHDLIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTA 247
H ++YRD+KP+N L+ + + DFG++K D + K + S GT
Sbjct: 221 HSLGIVYRDLKPENILLDADGH-----IKVTDFGLSKEAIDSEKKTY-------SFCGTV 268
Query: 248 RYMSINTHLGREQSRRDDMEALGHVFFYFLRGQLPWQG 285
YM+ R S D +LG + F L G LP+QG
Sbjct: 269 EYMAPEVINRRGHSMAADFWSLGVLMFEMLTGHLPFQG 306
>CE13014 [T] KOG0603 Ribosomal protein S6 kinase
Length = 740
Score = 60.1 bits (144), Expect = 8e-09
Identities = 58/218 (26%), Positives = 92/218 (41%), Gaps = 24/218 (11%)
Query: 77 YKIGKKIGEGSFGVLF-------EGVNMINNVPVAIKFEPRKTDAPQLKDEYRTYKILSG 129
+++ K +G+GSFG +F + + V K + D + K E +S
Sbjct: 47 FELLKVLGQGSFGKVFLVRKVRGRDSGHVYAMKVLKKATLKVRDRQRTKLERNILAHISH 106
Query: 130 SEGIPQAYYFGQEGLHNILVIDLLGPSLEDLFDWCGRR--FSIKTVVHVAIQMITLIEEL 187
+ Y F EG L++D L DLF + F+ V ++ +E L
Sbjct: 107 PFIVKLHYAFQTEG-KLYLILDFLRGG--DLFTRLSKEVMFTEDDVKFYLAELTLALEHL 163
Query: 188 HDHDLIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTA 247
H ++YRD+KP+N L+ + + DFG++K D + K + S GT
Sbjct: 164 HSLGIVYRDLKPENILLDADGH-----IKVTDFGLSKEAIDSEKKTY-------SFCGTV 211
Query: 248 RYMSINTHLGREQSRRDDMEALGHVFFYFLRGQLPWQG 285
YM+ R S D +LG + F L G LP+QG
Sbjct: 212 EYMAPEVINRRGHSMAADFWSLGVLMFEMLTGHLPFQG 249
>CE29300 [T] KOG0694 Serine/threonine protein kinase
Length = 431
Score = 59.7 bits (143), Expect = 1e-08
Identities = 64/246 (26%), Positives = 111/246 (45%), Gaps = 26/246 (10%)
Query: 77 YKIGKKIGEGSFGVLFEGVNMINNV-PVAIKFEPR-----KTDAPQLKDEYRTYKILSGS 130
+ + +++G GSFGV++ + ++ AIK + + K Q+K E ++L
Sbjct: 121 FVLERQLGRGSFGVVYCASAIHDSERKFAIKMQEKREIISKRAVLQVKREASIQRLLPSH 180
Query: 131 EGIPQAYYFGQEGLHNILVIDLLGPSLEDLFDWCGRRFSIK--TVVHVAIQMITLIEELH 188
I + Y Q H ++ S DLF +R S+ + + ++ + I+ LH
Sbjct: 181 PFIARTYSTWQTRTHLYSLLQYPTGSTGDLFSVWRQRGSLSEAAIRLIGAELASAIDFLH 240
Query: 189 DHDLIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTAR 248
+D+IYRD+K +N ++ + LIDFG+AK K KQ ++ GT +
Sbjct: 241 QNDVIYRDVKLENVVLDQWGH-----ALLIDFGLAK-----KLKQG---SSTGTICGTLQ 287
Query: 249 YMSINTHLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKAANN-KLKY----EKIGEKKR 303
YMS + G S D +LG + L G P+ +A ++ LK+ IG +
Sbjct: 288 YMSPDVASGGTYSHYVDWWSLGVLLHILLTGIYPYPNSEATHHANLKFIDYSTPIGCSRE 347
Query: 304 STNVYD 309
N+ D
Sbjct: 348 FANLMD 353
>CE29299 [T] KOG0694 Serine/threonine protein kinase
Length = 436
Score = 59.7 bits (143), Expect = 1e-08
Identities = 64/246 (26%), Positives = 111/246 (45%), Gaps = 26/246 (10%)
Query: 77 YKIGKKIGEGSFGVLFEGVNMINNV-PVAIKFEPR-----KTDAPQLKDEYRTYKILSGS 130
+ + +++G GSFGV++ + ++ AIK + + K Q+K E ++L
Sbjct: 121 FVLERQLGRGSFGVVYCASAIHDSERKFAIKMQEKREIISKRAVLQVKREASIQRLLPSH 180
Query: 131 EGIPQAYYFGQEGLHNILVIDLLGPSLEDLFDWCGRRFSIK--TVVHVAIQMITLIEELH 188
I + Y Q H ++ S DLF +R S+ + + ++ + I+ LH
Sbjct: 181 PFIARTYSTWQTRTHLYSLLQYPTGSTGDLFSVWRQRGSLSEAAIRLIGAELASAIDFLH 240
Query: 189 DHDLIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTAR 248
+D+IYRD+K +N ++ + LIDFG+AK K KQ ++ GT +
Sbjct: 241 QNDVIYRDVKLENVVLDQWGH-----ALLIDFGLAK-----KLKQG---SSTGTICGTLQ 287
Query: 249 YMSINTHLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKAANN-KLKY----EKIGEKKR 303
YMS + G S D +LG + L G P+ +A ++ LK+ IG +
Sbjct: 288 YMSPDVASGGTYSHYVDWWSLGVLLHILLTGIYPYPNSEATHHANLKFIDYSTPIGCSRE 347
Query: 304 STNVYD 309
N+ D
Sbjct: 348 FANLMD 353
>At1g49580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 606
Score = 59.7 bits (143), Expect = 1e-08
Identities = 54/215 (25%), Positives = 100/215 (46%), Gaps = 20/215 (9%)
Query: 78 KIGKKIGEGSFGVLFEGV---NMINNVPVAIKFEPRK--TDAPQLKDEYRTYKIL---SG 129
++G++IG G FG + VA+K P+ T A ++D R KIL SG
Sbjct: 151 ELGEEIGRGHFGYTCSAKFKKGELKGQVVAVKIIPKSKMTTAIAIEDVRREVKILQALSG 210
Query: 130 SEGIPQAYYFGQEGLHNILVIDLL-GPSLEDLFDWCGRRFSIKTVVHVAIQMITLIEELH 188
+ + Q Y ++ + + ++L G L D G ++S V IQ++ ++ H
Sbjct: 211 HKNLVQFYDAFEDNANVYIAMELCEGGELLDRILARGGKYSENDAKPVIIQILNVVAFCH 270
Query: 189 DHDLIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTAR 248
+++RD+KP+NFL ++ + + + IDFG++ R P + G+A
Sbjct: 271 FQGVVHRDLKPENFLY--TSKEENSQLKAIDFGLSDFVR--------PDERLNDIVGSAY 320
Query: 249 YMSINTHLGREQSRRDDMEALGHVFFYFLRGQLPW 283
Y++ L R + D+ ++G + + L G P+
Sbjct: 321 YVAPEV-LHRSYTTEADVWSIGVIAYILLCGSRPF 354
>YGL158w [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 512
Score = 59.3 bits (142), Expect = 1e-08
Identities = 62/247 (25%), Positives = 105/247 (42%), Gaps = 49/247 (19%)
Query: 76 HYKIGKKIGEGSFGVLFE--GVNMINNVPVAIKFEPRK----------------TDAPQL 117
+YK+ KIGEG+F +F+ G+N + PVAIK +K + ++
Sbjct: 120 NYKLLNKIGEGAFSRVFKAVGINTDDQAPVAIKAIIKKGISSDAILKGNDRIQGSSRKKV 179
Query: 118 KDEYRTYKILSGSEGIPQAYYFGQEGLHNILVIDLLGPSLEDLFDWCGRR--FSIKTVVH 175
+E +K++S + + QE + ++ L E +FD + FS H
Sbjct: 180 LNEVAIHKLVSKNNPHCTKFIAFQESANYYYLVTELVTGGE-IFDRIVQLTCFSEDLARH 238
Query: 176 VAIQMITLIEELHDHDLIYRDIKPDNFLI---------GRPNQPD----------ANMVH 216
V Q+ I+ +H +++RD+KP+N L G + D +V
Sbjct: 239 VITQVAIAIKHMHYMGIVHRDVKPENLLFEPIPFYGLDGDMQKEDEFTLGVGGGGIGLVK 298
Query: 217 LIDFGMAKLYRDPKTKQHIPYREKKSLSGTARYMSINTHLGREQSRRDDMEALGHVFFYF 276
L+DFG+AK R+ K+ GT Y++ + S + DM ++G V F
Sbjct: 299 LMDFGLAKKLRN---------NTAKTPCGTIEYVASEVFTSKRYSMKVDMWSIGCVLFTL 349
Query: 277 LRGQLPW 283
L G P+
Sbjct: 350 LCGYPPF 356
>SPAC9G1.02 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and related
serine/threonine protein kinases
Length = 1401
Score = 59.3 bits (142), Expect = 1e-08
Identities = 60/225 (26%), Positives = 97/225 (42%), Gaps = 23/225 (10%)
Query: 73 VGLHYKIGKKIGEGSFGVLFEGVNMINNVPVA---IKFEPRKTDAPQLKDEYRTYKILSG 129
+ + ++ G + G FG ++ GVNM +A IK + +T + + +L
Sbjct: 1033 ITIRWQQGHFVRSGMFGDVYTGVNMETGDLLAVKEIKLQDSRTFRSTVDQIHNEMTVLER 1092
Query: 130 SEGIPQAYYFGQEGLHNILVIDLL----GPSLEDLFDWCGRRFSIKTVVHV-AIQMITLI 184
Y+G E +H V + G SL DL R + V+ V +Q++ +
Sbjct: 1093 LNHPNVVTYYGVE-VHREKVYIFMEFCQGGSLADLL--AHGRIEDENVLKVYVVQLLEGL 1149
Query: 185 EELHDHDLIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYR----EK 240
+H +++RDIKP N L+ M+ DFG A LY P T + Y E
Sbjct: 1150 AYIHSQHILHRDIKPANILLDH-----RGMIKYSDFGSA-LYVSPPTDPEVRYEDIQPEL 1203
Query: 241 KSLSGTARYMSINTHLGREQSRRDDME--ALGHVFFYFLRGQLPW 283
+ L+GT YM+ LG ++ M+ +LG V + G PW
Sbjct: 1204 QHLAGTPMYMAPEIILGTKKGDFGAMDIWSLGCVILEMMTGSTPW 1248
>At1g50230 [R] KOG0597 Serine-threonine protein kinase FUSED
Length = 269
Score = 58.9 bits (141), Expect = 2e-08
Identities = 58/211 (27%), Positives = 93/211 (43%), Gaps = 18/211 (8%)
Query: 77 YKIGKKIGEGSFGVLFEGVNMINNVPVAIKF--EPRKTDAP--QLKDEYRTYKILSGSEG 132
Y + + +GEGSFG +++G VA+KF + KTD L+ E + L
Sbjct: 6 YHVIELVGEGSFGRVYKGRRKYTGQTVAMKFIMKQGKTDKDIHSLRQEIEILRKLKHENI 65
Query: 133 IPQAYYFGQEGLHNILVIDLLGPSLEDLFDWCGRRFSIKTVVHVAIQMITLIEELHDHDL 192
I F ++ G E L D + + V +A Q++ ++ LH + +
Sbjct: 66 IEMLDSFENAREFCVVTEFAQGELFEILED--DKCLPEEQVQAIAKQLVKALDYLHSNRI 123
Query: 193 IYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTARYMSI 252
I+RD+KP N LIG ++V L DFG A R T + +S+ GT YM+
Sbjct: 124 IHRDMKPQNILIGA-----GSVVKLCDFGFA---RAMSTNTVV----LRSIKGTPLYMAP 171
Query: 253 NTHLGREQSRRDDMEALGHVFFYFLRGQLPW 283
+ R D+ +LG + + GQ P+
Sbjct: 172 ELVKEQPYDRTVDLWSLGVILYELYVGQPPF 202
>7297611 [T] KOG0614 cGMP-dependent protein kinase
Length = 1003
Score = 58.9 bits (141), Expect = 2e-08
Identities = 40/132 (30%), Positives = 65/132 (48%), Gaps = 18/132 (13%)
Query: 168 FSIKTVVHVAIQMITLIEELHDHDLIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYR 227
F KT +A ++ + LH H IYRD+KP+N ++G L+DFG AK R
Sbjct: 788 FDEKTAKFIAGCVVEAFDYLHSHHFIYRDLKPENLMLGTD-----GYCKLVDFGFAKFVR 842
Query: 228 DPKTKQHIPYREKKSLSGTARYMSINTHLGREQSRRDDMEALGHVFFYFLRGQLPWQGLK 287
+ + + +GT Y++ L R R D ALG + + L G+ P++G+
Sbjct: 843 QNE--------KTNTFAGTPEYVAPEIILDRGHDRAVDYWALGILVYELLVGKTPFRGV- 893
Query: 288 AANNKLK-YEKI 298
N++K Y++I
Sbjct: 894 ---NQIKIYQQI 902
>YOL100w [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 1081
Score = 58.5 bits (140), Expect = 2e-08
Identities = 43/129 (33%), Positives = 62/129 (47%), Gaps = 14/129 (10%)
Query: 175 HVAIQMITLIEELHDHDLIYRDIKPDNFLIGRPNQPDANM-VHLIDFGMAKLYRDPKTKQ 233
+ A Q+I I+ LH + +I+RDIKP+N L+ D M + L DFG AKL
Sbjct: 282 YYAAQIIDAIDYLHSNGIIHRDIKPENILL------DGEMKIKLTDFGTAKLLNPTNNSV 335
Query: 234 HIPYRE----KKSLSGTARYMSINTHLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKAA 289
P + KS GTA Y+S R D+ A G + F + G+ P+ KA
Sbjct: 336 SKPEYDLSTRSKSFVGTAEYVSPELLNDSFTDYRCDIWAFGCILFQMIAGKPPF---KAT 392
Query: 290 NNKLKYEKI 298
N L ++K+
Sbjct: 393 NEYLTFQKV 401
>HsM7657627 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 970
Score = 58.5 bits (140), Expect = 2e-08
Identities = 52/214 (24%), Positives = 99/214 (45%), Gaps = 21/214 (9%)
Query: 77 YKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPRKTD-----APQLKDEYRTYKILSGSE 131
+K+G +G+GSF ++ ++ + VAIK +K ++K+E + + L
Sbjct: 12 FKVGNLLGKGSFAGVYRAESIHTGLEVAIKMIDKKAMYKAGMVQRVKNEVKIHCQLK-HP 70
Query: 132 GIPQAYYFGQEGLHNILVIDLL-GPSLEDLFDWCGRRFSIKTVVHVAIQMITLIEELHDH 190
I + Y + ++ + LV+++ + + FS H Q+IT + LH H
Sbjct: 71 SILELYNYFEDSNYVYLVLEMCHNGEMNRYLKNRVKPFSENEARHFMHQIITGMLYLHSH 130
Query: 191 DLIYRDIKPDNFLIGRPNQPDANM-VHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTARY 249
+++RD+ N L+ R NM + + DFG+A T+ +P+ + +L GT Y
Sbjct: 131 GILHRDLTLSNLLLTR------NMNIKIADFGLA-------TQLKMPHEKHYTLCGTPNY 177
Query: 250 MSINTHLGREQSRRDDMEALGHVFFYFLRGQLPW 283
+S D+ +LG +F+ L G+ P+
Sbjct: 178 ISPEIATRSAHGLESDVWSLGCMFYTLLIGRPPF 211
>Hs4507719 [D] KOG0596 Dual specificity; serine/threonine and tyrosine kinase
Length = 841
Score = 58.5 bits (140), Expect = 2e-08
Identities = 63/240 (26%), Positives = 105/240 (43%), Gaps = 33/240 (13%)
Query: 72 IVGLHYKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPRKTDAPQLKDEYRTY-----KI 126
+ G Y I K+IG G +F+ +N + AIK+ + Q D YR K+
Sbjct: 504 VKGRIYSILKQIGSGGSSKVFQVLNEKKQI-YAIKYVNLEEADNQTLDSYRNEIAYLNKL 562
Query: 127 LSGSEGIPQAYYFGQEGLHNILVIDLLGPSLEDLFDWCGRRFSIKTVVHVAI--QMITLI 184
S+ I + Y + + +V++ DL W ++ SI + M+ +
Sbjct: 563 QQHSDKIIRLYDYEITDQYIYMVMEC---GNIDLNSWLKKKKSIDPWERKSYWKNMLEAV 619
Query: 185 EELHDHDLIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLS 244
+H H +++ D+KP NFLI M+ LIDFG+A P T + K S
Sbjct: 620 HTIHQHGIVHSDLKPANFLI------VDGMLKLIDFGIAN-QMQPDTTSVV----KDSQV 668
Query: 245 GTARY--------MSINTHLGREQSR---RDDMEALGHVFFYFLRGQLPWQGLKAANNKL 293
GT Y MS + G+ +S+ + D+ +LG + +Y G+ P+Q + +KL
Sbjct: 669 GTVNYMPPEAIKDMSSSRENGKSKSKISPKSDVWSLGCILYYMTYGKTPFQQIINQISKL 728
>Hs4505695 [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 556
Score = 58.5 bits (140), Expect = 2e-08
Identities = 67/279 (24%), Positives = 119/279 (42%), Gaps = 46/279 (16%)
Query: 77 YKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPRKTDAPQLKDEYRTYK--ILSGSEGI- 133
+K GK +GEGSF + + + AIK ++ + K Y T + ++S +
Sbjct: 82 FKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDHPF 141
Query: 134 ----------PQAYYFGQEGLHNILVIDLLGPSLEDLFDWCGRRFSIKTVVHVAIQMITL 183
+ YFG N ++ + + + C R ++ ++++
Sbjct: 142 FVKLYFTFQDDEKLYFGLSYAKNGELLKYIR-KIGSFDETCTRFYTA--------EIVSA 192
Query: 184 IEELHDHDLIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSL 243
+E LH +I+RD+KP+N L+ + + DFG AK+ P++KQ S
Sbjct: 193 LEYLHGKGIIHRDLKPENILLNEDMH-----IQITDFGTAKVL-SPESKQ----ARANSF 242
Query: 244 SGTARYMSINTHLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKAANNKLKYEKIGE--- 300
GTA+Y+S + + D+ ALG + + + G P+ +A N L ++KI +
Sbjct: 243 VGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPF---RAGNEYLIFQKIIKLEY 299
Query: 301 ---KKRSTNVYDLSQGLPVQFGRYLEIVRNLGFEETPDY 336
+K DL + L V L+ + LG EE Y
Sbjct: 300 DFPEKFFPKARDLVEKLLV-----LDATKRLGCEEMEGY 333
>Hs20547712 [D] KOG0596 Dual specificity; serine/threonine and tyrosine kinase
Length = 841
Score = 58.5 bits (140), Expect = 2e-08
Identities = 63/240 (26%), Positives = 105/240 (43%), Gaps = 33/240 (13%)
Query: 72 IVGLHYKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPRKTDAPQLKDEYRTY-----KI 126
+ G Y I K+IG G +F+ +N + AIK+ + Q D YR K+
Sbjct: 504 VKGRIYSILKQIGSGGSSKVFQVLNEKKQI-YAIKYVNLEEADNQTLDSYRNEIAYLNKL 562
Query: 127 LSGSEGIPQAYYFGQEGLHNILVIDLLGPSLEDLFDWCGRRFSIKTVVHVAI--QMITLI 184
S+ I + Y + + +V++ DL W ++ SI + M+ +
Sbjct: 563 QQHSDKIIRLYDYEITDQYIYMVMEC---GNIDLNSWLKKKKSIDPWERKSYWKNMLEAV 619
Query: 185 EELHDHDLIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLS 244
+H H +++ D+KP NFLI M+ LIDFG+A P T + K S
Sbjct: 620 HTIHQHGIVHSDLKPANFLI------VDGMLKLIDFGIAN-QMQPDTTSVV----KDSQV 668
Query: 245 GTARY--------MSINTHLGREQSR---RDDMEALGHVFFYFLRGQLPWQGLKAANNKL 293
GT Y MS + G+ +S+ + D+ +LG + +Y G+ P+Q + +KL
Sbjct: 669 GTVNYMPPEAIKDMSSSRENGKSKSKISPKSDVWSLGCILYYMTYGKTPFQQIINQISKL 728
>CE20142 [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 320
Score = 58.5 bits (140), Expect = 2e-08
Identities = 55/231 (23%), Positives = 96/231 (40%), Gaps = 26/231 (11%)
Query: 77 YKIGKKIGEGSFGVLF----EGVNMINNVPVAIKFEPRKTD-----APQLKDEYRTYKIL 127
Y + K++GEGSF ++ + N VA+K ++ P + E ++
Sbjct: 26 YSVEKEVGEGSFSTVYLARRKEPKNDENPEVALKICLKRLILKNKMVPYIHREKEALALI 85
Query: 128 SGSE----GIPQAY--YFGQEGLHNILVIDLLGPSLEDLFDWCGRRFSIKTVVHVAIQMI 181
S E GI Y + E L+ +L G + +F++ + A ++
Sbjct: 86 SREENAHPGIVTLYATFQDSESLYFVLEYAKYGDLCTLMQKQPDSKFNVADSRYYAANLL 145
Query: 182 TLIEELHDHDLIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYRE-- 239
+ +E +H +I+RD+K DN L+ + + L DFG +K D + Q P E
Sbjct: 146 SALEHIHKLGIIHRDVKADNLLVKSDGR-----IMLTDFGSSKFLSDYQKIQENPVEEEQ 200
Query: 240 ----KKSLSGTARYMSINTHLGREQSRRDDMEALGHVFFYFLRGQLPWQGL 286
+ S GTA +++ G E S D+ A + FL G P+ +
Sbjct: 201 PTGRRSSFVGTAFFVTPELLTGSEMSPSSDLWAFSVTLYLFLTGIYPFNDM 251
>YCR073c [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and related
serine/threonine protein kinases
Length = 1331
Score = 58.2 bits (139), Expect = 3e-08
Identities = 60/237 (25%), Positives = 104/237 (43%), Gaps = 34/237 (14%)
Query: 73 VGLHYKIGKKIGEGSFGVLFEGVNMINNVPVAIK------FEPRKTDAPQLKDEYRTYKI 126
V + ++ IG G+FG ++ +N+ N +A+K K P +K+E ++
Sbjct: 1030 VSMRWQKRSFIGGGTFGQVYSAINLENGEILAVKEIKIHDTTTMKKIFPLIKEEMTVLEM 1089
Query: 127 LSGSEGIPQAYYFGQEGLH----NILVIDLLGPSLEDLFDWCGRRFSIKTVVHVAIQMIT 182
L+ + Y+G E +H NI + G SL L D + T V+ +++
Sbjct: 1090 LNHPNIVQ---YYGVE-VHRDKVNIFMEYCEGGSLASLLDHGRIEDEMVTQVYT-FELLE 1144
Query: 183 LIEELHDHDLIYRDIKPDNFLIGRPNQPDAN-MVHLIDFGMAKLYRDPKTKQ-------- 233
+ LH +++RDIKP+N L+ D N ++ +DFG A+ +T+
Sbjct: 1145 GLAYLHQSGVVHRDIKPENILL------DFNGIIKYVDFGTARTVVGSRTRTVRNAAVQD 1198
Query: 234 -HIPYREKKSLSGTARYMSINTHLG---REQSRRDDMEALGHVFFYFLRGQLPWQGL 286
+ + + GT YM+ T G + + DD+ ALG V G+ PW L
Sbjct: 1199 FGVETKSLNEMMGTPMYMAPETISGSAVKGKLGADDVWALGCVVLEMATGRRPWSNL 1255
>SPBC4C3.11 [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 420
Score = 58.2 bits (139), Expect = 3e-08
Identities = 63/222 (28%), Positives = 99/222 (44%), Gaps = 16/222 (7%)
Query: 77 YKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPRKTDAPQLKDEYRTYKI-----LSGSE 131
Y G IG+GSF + + + AIK +K + K +Y + L+G
Sbjct: 54 YVFGDIIGDGSFSKVRRATDKKSWKEYAIKVLDKKYIVKENKVKYVNIERDSMMRLNGFP 113
Query: 132 GIPQAYYFGQEGLHNILVIDLLGPSLEDLFDWCGRRFSIKTVVHV-AIQMITLIEELHDH 190
GI + ++ Q+ L V++L P+ E L RF + V A ++++ IE +H
Sbjct: 114 GISRLFHTFQDDLKLYYVLEL-APNGELLQYIKKYRFLDENCVRFYAAEILSSIEYMHSC 172
Query: 191 DLIYRDIKPDNFLIGRPNQPDANM-VHLIDFGMAKLYRDPKTKQHIPYRE-KKSLSGTAR 248
+I+RD+KP+N L D NM V + DFG AK+ PK Y S GTA
Sbjct: 173 GIIHRDLKPENILF------DGNMHVKITDFGTAKIL-PPKYVNSPDYTTFPSSFVGTAE 225
Query: 249 YMSINTHLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKAAN 290
Y++ + S+ D+ A V + + G P+ G N
Sbjct: 226 YVAPELLSRQVVSKSSDLWAFACVVYQMIVGSPPFHGSNPNN 267
>Hs5174547 [T] KOG4279 Serine/threonine protein kinase
Length = 1374
Score = 58.2 bits (139), Expect = 3e-08
Identities = 53/212 (25%), Positives = 99/212 (46%), Gaps = 21/212 (9%)
Query: 83 IGEGSFGVLFEGVNMINNVPVAIKFEPRKTD--APQLKDEYRTYKILSGSEGIPQAYYFG 140
+G+G++G+++ G ++ N V +AIK P + + L +E +K L + F
Sbjct: 686 LGKGTYGIVYAGRDLSNQVRIAIKEIPERDSRYSQPLHEEIALHKHLKHKNIVQYLGSFS 745
Query: 141 QEGLHNILVIDLLGPSLEDLF--DWCGRRFSIKTVVHVAIQMITLIEELHDHDLIYRDIK 198
+ G I + + G SL L W + + +T+ Q++ ++ LHD+ +++RDIK
Sbjct: 746 ENGFIKIFMEQVPGGSLSALLRSKWGPLKDNEQTIGFYTKQILEGLKYLHDNQIVHRDIK 805
Query: 199 PDNFLIGRPNQPDANMVHLIDFGMAKLYR--DPKTKQHIPYREKKSLSGTARYMS--INT 254
DN LI + ++ + DFG +K +P T ++ +GT +YM+ I
Sbjct: 806 GDNVLI----NTYSGVLKISDFGTSKRLAGINPCT---------ETFTGTLQYMAPEIID 852
Query: 255 HLGREQSRRDDMEALGHVFFYFLRGQLPWQGL 286
R + D+ +LG G+ P+ L
Sbjct: 853 KGPRGYGKAADIWSLGCTIIEMATGKPPFYEL 884
>CE26076 [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 503
Score = 58.2 bits (139), Expect = 3e-08
Identities = 61/229 (26%), Positives = 99/229 (42%), Gaps = 46/229 (20%)
Query: 77 YKIGKKIGEGSFGVLFEGVNMIN-NVPVAIK----FEPRKTDAPQLKDEYRTYKILS--- 128
Y++ + +GEG+FG + VN N V A+K K ++ EY K +S
Sbjct: 24 YRVVQTLGEGAFGEVLLIVNTKNPEVAAAMKKINIANKSKDFIDNIRKEYLLQKRVSAVG 83
Query: 129 --------GSEGIPQAYYFGQEGLHNILVIDLLGPSLEDLFDWCGR-----RFSIKTVVH 175
G PQ YY E + D + P CG +F K
Sbjct: 84 HDNVIRMIGMRNDPQFYYLFLEYADGGELFDKIEPD-------CGMSPVFAQFYFK---- 132
Query: 176 VAIQMITLIEELHDHDLIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHI 235
Q+I ++ +HD+D+++RDIKP+N L+ +++ + DFGMA LYR+ ++ +
Sbjct: 133 ---QLICGLKFIHDNDVVHRDIKPENLLL-----TGTHVLKISDFGMATLYRNKGEERLL 184
Query: 236 PYREKKSLSGTARYMSINTHLGRE-QSRRDDMEALGHVFFYFLRGQLPW 283
GT Y + G++ + D+ + G V L G+LPW
Sbjct: 185 DLS-----CGTIPYAAPELCAGKKYRGPPVDVWSSGIVLIAMLTGELPW 228
>At3g49370 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 594
Score = 57.8 bits (138), Expect = 4e-08
Identities = 55/218 (25%), Positives = 102/218 (46%), Gaps = 20/218 (9%)
Query: 77 YKIGKKIGEGSFGVLF-----EGVNMINNVPVAIKFEPRKTDAPQLKD---EYRTYKILS 128
Y++G+++G G FG +G V V I + + T A ++D E + K LS
Sbjct: 142 YELGREVGRGHFGHTCWAKAKKGKIKGQTVAVKIISKSKMTSALSIEDVRREVKLLKALS 201
Query: 129 GSEGIPQAYYFGQEGLHNILVIDLL-GPSLEDLFDWCGRRFSIKTVVHVAIQMITLIEEL 187
G + + Y ++ + +V++L G L D G R+ + +Q+++
Sbjct: 202 GHSHMVKFYDVFEDSDNVFVVMELCEGGELLDSILARGGRYPEAEAKRILVQILSATAFF 261
Query: 188 HDHDLIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTA 247
H +++RD+KP+NFL N+ DA ++ +IDFG++ R + + G+A
Sbjct: 262 HLQGVVHRDLKPENFLFTSKNE-DA-VLKVIDFGLSDYARFD--------QRLNDVVGSA 311
Query: 248 RYMSINTHLGREQSRRDDMEALGHVFFYFLRGQLPWQG 285
Y++ L R S D+ ++G + + L G P+ G
Sbjct: 312 YYVAPEV-LHRSYSTEADIWSIGVISYILLCGSRPFYG 348
>YPL209c [D] KOG0580 Serine/threonine protein kinase
Length = 367
Score = 57.4 bits (137), Expect = 5e-08
Identities = 56/213 (26%), Positives = 98/213 (45%), Gaps = 19/213 (8%)
Query: 77 YKIGKKIGEGSFGVLFEGVNMINNVPVAIK-FEPRKTDAPQLKDEYRTYKILSGSEGIP- 134
+++GKK+G+G FG ++ + A+K E + L+ ++R + S P
Sbjct: 104 FELGKKLGKGKFGKVYCVRHRSTGYICALKVMEKEEIIKYNLQKQFRREVEIQTSLNHPN 163
Query: 135 --QAY-YFGQEGLHNILVIDLLGPSLEDLFDWCGRRFSIKTVVHVAIQMITLIEELHDHD 191
++Y YF E +L+ L+ + L G I ++ Q+ ++ +H +
Sbjct: 164 LTKSYGYFHDEKRVYLLMEYLVNGEMYKLLRLHGPFNDILASDYI-YQIANALDYMHKKN 222
Query: 192 LIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTARYMS 251
+I+RDIKP+N LIG N++ L DFG + + + P +K++ GT Y+S
Sbjct: 223 IIHRDIKPENILIG-----FNNVIKLTDFGWSII--------NPPENRRKTVCGTIDYLS 269
Query: 252 INTHLGREQSRRDDMEALGHVFFYFLRGQLPWQ 284
RE D ALG + F L G P++
Sbjct: 270 PEMVESREYDHTIDAWALGVLAFELLTGAPPFE 302
>Hs21361433 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 970
Score = 57.4 bits (137), Expect = 5e-08
Identities = 51/214 (23%), Positives = 100/214 (45%), Gaps = 21/214 (9%)
Query: 77 YKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPRKTD-----APQLKDEYRTYKILSGSE 131
+K+G +G+GSF ++ ++ + + VAIK +K ++++E + + L
Sbjct: 12 FKVGNLLGKGSFAGVYRAESIHSGLEVAIKMIDKKAMYKAGMVQRVQNEVKIHCQLK-HP 70
Query: 132 GIPQAYYFGQEGLHNILVIDLL-GPSLEDLFDWCGRRFSIKTVVHVAIQMITLIEELHDH 190
I + Y + ++ + LV+++ + + FS H Q+IT + LH H
Sbjct: 71 SILELYNYFEDSNYVYLVLEMCHNGEMNRYLKNRVKPFSENEARHFMHQIITGMLYLHSH 130
Query: 191 DLIYRDIKPDNFLIGRPNQPDANM-VHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTARY 249
+++RD+ N L+ R NM + + DFG+A T+ +P+ + +L GT Y
Sbjct: 131 GILHRDLTLSNLLLTR------NMNIKIADFGLA-------TQLKMPHEKHYTLCGTPNY 177
Query: 250 MSINTHLGREQSRRDDMEALGHVFFYFLRGQLPW 283
+S D+ +LG +F+ L G+ P+
Sbjct: 178 ISPEIATRSAHGLESDVWSLGCMFYTLLIGRPPF 211
>Hs4759050 [T] KOG0603 Ribosomal protein S6 kinase
Length = 740
Score = 57.0 bits (136), Expect = 7e-08
Identities = 56/218 (25%), Positives = 94/218 (42%), Gaps = 24/218 (11%)
Query: 77 YKIGKKIGEGSFGVLF-------EGVNMINNVPVAIKFEPRKTDAPQLKDEYRTYKILSG 129
+++ K +G+GSFG +F + + V K + D + K E ++
Sbjct: 68 FELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKATLKVRDRVRTKMERDILVEVNH 127
Query: 130 SEGIPQAYYFGQEGLHNILVIDLLGPSLEDLFDWCGRR--FSIKTVVHVAIQMITLIEEL 187
+ Y F EG L++D L DLF + F+ + V ++ ++ L
Sbjct: 128 PFIVKLHYAFQTEG-KLYLILDFLRGG--DLFTRLSKEVMFTEEDVKFYLAELALALDHL 184
Query: 188 HDHDLIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTA 247
H +IYRD+KP+N L+ + + L DFG++K D + K + S GT
Sbjct: 185 HSLGIIYRDLKPENILL-----DEEGHIKLTDFGLSKESIDHEKKAY-------SFCGTV 232
Query: 248 RYMSINTHLGREQSRRDDMEALGHVFFYFLRGQLPWQG 285
YM+ R ++ D + G + F L G LP+QG
Sbjct: 233 EYMAPEVVNRRGHTQSADWWSFGVLMFEMLTGTLPFQG 270
>Hs20149547 [T] KOG0603 Ribosomal protein S6 kinase
Length = 735
Score = 57.0 bits (136), Expect = 7e-08
Identities = 57/219 (26%), Positives = 94/219 (42%), Gaps = 24/219 (10%)
Query: 76 HYKIGKKIGEGSFGVLF-------EGVNMINNVPVAIKFEPRKTDAPQLKDEYRTYKILS 128
H+++ K +G+GSFG +F + + V K + D + K E ++
Sbjct: 61 HFELLKVLGQGSFGKVFLVRKVTRPDSGHLYAMKVLKKATLKVRDRVRTKMERDILADVN 120
Query: 129 GSEGIPQAYYFGQEGLHNILVIDLLGPSLEDLFDWCGRR--FSIKTVVHVAIQMITLIEE 186
+ Y F EG L++D L DLF + F+ + V ++ ++
Sbjct: 121 HPFVVKLHYAFQTEG-KLYLILDFLRGG--DLFTRLSKEVMFTEEDVKFYLAELALGLDH 177
Query: 187 LHDHDLIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGT 246
LH +IYRD+KP+N L+ + + L DFG++K D + K + S GT
Sbjct: 178 LHSLGIIYRDLKPENILL-----DEEGHIKLTDFGLSKEAIDHEKKAY-------SFCGT 225
Query: 247 ARYMSINTHLGREQSRRDDMEALGHVFFYFLRGQLPWQG 285
YM+ + S D + G + F L G LP+QG
Sbjct: 226 VEYMAPEVVNRQGHSHSADWWSYGVLMFEMLTGSLPFQG 264
>At5g50180 [T] KOG0192 Tyrosine kinase specific for activated (GTP-bound)
p21cdc42Hs
Length = 346
Score = 57.0 bits (136), Expect = 7e-08
Identities = 67/285 (23%), Positives = 122/285 (42%), Gaps = 24/285 (8%)
Query: 79 IGKKIGEGSFGVLFEGVNMINNVPVAIKFEPRKTDAPQLKDE----YRTYKILSGSEGIP 134
+G KIGEG+ ++EG N VAIK R ++ R ++LS +
Sbjct: 22 VGPKIGEGAHAKVYEG--KYKNQTVAIKIVHRGETPEEIAKRDSRFLREVEMLSRVQHKN 79
Query: 135 QAYYFG--QEGLHNILVIDLLGPSLED-LFDWCGRRFSIKTVVHVAIQMITLIEELHDHD 191
+ G +E + I+ L G +L L + + + A+ + +E LH H
Sbjct: 80 LVKFIGACKEPVMVIVTELLQGGTLRKYLLNLRPACLETRVAIGFALDIARGMECLHSHG 139
Query: 192 LIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTARYMS 251
+I+RD+KP+N L+ D V L DFG+A+ + T+ Y +
Sbjct: 140 IIHRDLKPENLLL----TADHKTVKLADFGLAR--EESLTEMMTAETGTYRWMAPELYST 193
Query: 252 INTHLGREQ--SRRDDMEALGHVFFYFLRGQLPWQGLKAANNKLKYEKIGEKKRSTNVYD 309
+ LG ++ + + D + V + L +LP++G+ +N + Y + NV
Sbjct: 194 VTLRLGEKKHYNHKVDAYSFAIVLWELLHNKLPFEGM--SNLQAAYAAAFK-----NVRP 246
Query: 310 LSQGLPVQFGRYLEIVRNLGFEETPDYEGYRKLLLSVLDELGQKL 354
++ LP + G + N P++ +LLL+ L ++G +
Sbjct: 247 SAESLPEELGDIVTSCWNEDPNARPNFTHIIELLLNYLSKVGSPI 291
>At1g76040 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 534
Score = 57.0 bits (136), Expect = 7e-08
Identities = 57/235 (24%), Positives = 109/235 (46%), Gaps = 27/235 (11%)
Query: 77 YKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEP-----RKTDAPQLKDEYRTYKILSGSE 131
Y + K++G G FG+ ++ + N A K R+ D ++ E + L+G
Sbjct: 85 YDLHKELGRGQFGITYKCTDKSNGREYACKSISKRKLIRRKDIEDVRREVMILQHLTGQP 144
Query: 132 GIPQ--AYYFGQEGLHNILVIDLLGPSLEDLFDWCGRR--FSIKTVVHVAIQMITLIEEL 187
I + Y ++ LH LV++L +LFD ++ +S K ++ Q++ ++
Sbjct: 145 NIVEFRGAYEDKDNLH--LVMELCSGG--ELFDRIIKKGSYSEKEAANIFRQIVNVVHVC 200
Query: 188 HDHDLIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTA 247
H +++RD+KP+NFL+ + + + + DFG++ + K YR+ + G+A
Sbjct: 201 HFMGVVHRDLKPENFLL--VSNEEDSPIKATDFGLSVFIEEGKV-----YRD---IVGSA 250
Query: 248 RYMSINTHLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKAANNKLKYEKIGEKK 302
Y++ L R + D+ + G + + L G P+ G K +E I E K
Sbjct: 251 YYVAPEV-LHRNYGKEIDVWSAGVMLYILLSGVPPFWG---ETEKTIFEAILEGK 301
>Hs7657526 [T] KOG0603 Ribosomal protein S6 kinase
Length = 745
Score = 56.6 bits (135), Expect = 9e-08
Identities = 55/218 (25%), Positives = 94/218 (42%), Gaps = 24/218 (11%)
Query: 77 YKIGKKIGEGSFGVLF-------EGVNMINNVPVAIKFEPRKTDAPQLKDEYRTYKILSG 129
+++ K +G+GSFG +F + + V K + D + K E ++
Sbjct: 73 FELLKVLGQGSFGKVFLVRKKTGPDAGQLYAMKVLKKASLKVRDRVRTKMERDILVEVNH 132
Query: 130 SEGIPQAYYFGQEGLHNILVIDLLGPSLEDLFDWCGRR--FSIKTVVHVAIQMITLIEEL 187
+ Y F EG L++D L D+F + F+ + V ++ ++ L
Sbjct: 133 PFIVKLHYAFQTEG-KLYLILDFLRGG--DVFTRLSKEVLFTEEDVKFYLAELALALDHL 189
Query: 188 HDHDLIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTA 247
H ++YRD+KP+N L+ + + L DFG++K D + K + S GT
Sbjct: 190 HQLGIVYRDLKPENILL-----DEIGHIKLTDFGLSKESVDQEKKAY-------SFCGTV 237
Query: 248 RYMSINTHLGREQSRRDDMEALGHVFFYFLRGQLPWQG 285
YM+ R S+ D + G + F L G LP+QG
Sbjct: 238 EYMAPEVVNRRGHSQSADWWSYGVLMFEMLTGTLPFQG 275
>Hs5730055 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 685
Score = 56.6 bits (135), Expect = 9e-08
Identities = 58/245 (23%), Positives = 102/245 (40%), Gaps = 43/245 (17%)
Query: 74 GLHYKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPRKTDAP-----QLKDEYRTYKILS 128
G Y GK +G+G F +E ++ NN A K P A ++ E ++IL
Sbjct: 79 GKRYCRGKVLGKGGFAKCYEMTDLTNNKVYAAKIIPHSRVAKPHQREKIDKEIELHRILH 138
Query: 129 GSEGIPQAYYFGQEGLHNILVIDLLGPSLEDLFDWCGRR-----------FSIKTVVHVA 177
+ +YF E NI + L ++C RR + V +
Sbjct: 139 HKHVVQFYHYF--EDKENIYI----------LLEYCSRRSMAHILKARKVLTEPEVRYYL 186
Query: 178 IQMITLIEELHDHDLIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPY 237
Q+++ ++ LH+ ++++RD+K NF I +A + + DFG+A +
Sbjct: 187 RQIVSGLKYLHEQEILHRDLKLGNFFIN-----EAMELKVGDFGLAARLEPLE------- 234
Query: 238 REKKSLSGTARYMSINTHLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKAANNKLKYEK 297
++++ GT Y+S + D+ ALG V + L G+ P++ N K Y
Sbjct: 235 HRRRTICGTPNYLSPEVLNKQGHGCESDIWALGCVMYTMLLGRPPFE---TTNLKETYRC 291
Query: 298 IGEKK 302
I E +
Sbjct: 292 IREAR 296
>Hs14042966 [T] KOG0583 Serine/threonine protein kinase
Length = 273
Score = 56.6 bits (135), Expect = 9e-08
Identities = 58/217 (26%), Positives = 93/217 (42%), Gaps = 22/217 (10%)
Query: 75 LHYKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPRKTDAPQLKDEY--RTYKILSGSEG 132
L YK+G+ IGEGS+ + + VAIK R+ P +++ R IL G
Sbjct: 10 LGYKLGRTIGEGSYSKVKVATSKKYKGTVAIKVVDRRRAPPDFVNKFLPRELSILRGVRH 69
Query: 133 IPQAYYFGQEGLHNILVIDLLGPSLEDLFDWCGRRFSIKTVV--HVAIQMITLIEELHDH 190
+ F + N + ++ + DL R I V + Q+ + LHDH
Sbjct: 70 PHIVHVFEFIEVCNGKLYIVMEAAATDLLQAVQRNGRIPGVQARDLFAQIAGAVRYLHDH 129
Query: 191 DLIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKL---YRDPKTKQHIPYREKKSLSGTA 247
L++RD+K +N L+ PD V L DFG + Y D T + G+A
Sbjct: 130 HLVHRDLKCENVLL----SPDERRVKLTDFGFGRQAHGYPDLST----------TYCGSA 175
Query: 248 RYMSINTHLG-REQSRRDDMEALGHVFFYFLRGQLPW 283
Y S LG ++ D+ ++G V + + G +P+
Sbjct: 176 AYASPEVLLGIPYDPKKYDVWSMGVVLYVMVTGCMPF 212
>7295431 [D] KOG0601 Cyclin-dependent kinase WEE1
Length = 770
Score = 56.6 bits (135), Expect = 9e-08
Identities = 48/174 (27%), Positives = 80/174 (45%), Gaps = 17/174 (9%)
Query: 82 KIGEGSFGVLFEGVNMINNVPVAIKFEPRKTDAPQLK----DEYRTYKILSGSEGIPQAY 137
K+GEGSFG +F+ + + A+K + Q + +E R Y+ SG E +
Sbjct: 107 KLGEGSFGEVFQVRDRSDGQLYAVKISKQLFRGEQYRAERLEEVRRYEEFSGHENCIRFI 166
Query: 138 YFGQEGLHNILVIDLLGPSLEDLFDWCGRRFSIKTVVHVAIQMITLIEELHDHDLIYRDI 197
++ + ++L SLE C +R + + H+ + ++ ++ LHD +LI+ DI
Sbjct: 167 RAWEQYDRLYMQMELCRESLEQYLLRC-QRIPEERIWHILLDLLRGLKSLHDRNLIHLDI 225
Query: 198 KPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTARYMS 251
K DN LIG D L DFG+ + D H + G +RYM+
Sbjct: 226 KLDNVLIGE----DDETCKLADFGLV-IDVDRANSHH-------ATEGDSRYMA 267
>Hs4758652 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 358
Score = 56.2 bits (134), Expect = 1e-07
Identities = 64/218 (29%), Positives = 92/218 (41%), Gaps = 29/218 (13%)
Query: 78 KIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPRKTDAPQLKD----EYRTYKILSGSEGI 133
KIGK IGEGS+GV+F+ N VAIK D P +K E R K L +
Sbjct: 7 KIGK-IGEGSYGVVFKCRNRDTGQIVAIKKFLESEDDPVIKKIALREIRMLKQLKHPNLV 65
Query: 134 PQAYYFGQEG-LHNILVIDLLGPSLEDLFDWCGRRFSIKTVVHVAIQMITLIEELHDHDL 192
F ++ LH LV + ++ D R V + Q + + H H+
Sbjct: 66 NLLEVFRRKRRLH--LVFEYCDHTVLHELDRYQRGVPEHLVKSITWQTLQAVNFCHKHNC 123
Query: 193 IYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKT--KQHIP---YREKKSLSGTA 247
I+RD+KP+N LI + +++ L DFG A+L P ++ YR + L G
Sbjct: 124 IHRDVKPENILITK-----HSVIKLCDFGFARLLTGPSDYYTDYVATRWYRSPELLVGDT 178
Query: 248 RYMSINTHLGREQSRRDDMEALGHVFFYFLRGQLPWQG 285
+Y D+ A+G VF L G W G
Sbjct: 179 QY-----------GPPVDVWAIGCVFAELLSGVPLWPG 205
>Hs20479818 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 514
Score = 56.2 bits (134), Expect = 1e-07
Identities = 58/225 (25%), Positives = 101/225 (44%), Gaps = 17/225 (7%)
Query: 77 YKIGKKIGEGSFGVLFEGVNMINNVPVAIK-FEPRKTDAPQLKDEYRTYKILSG--SEGI 133
Y G+ +G+GSFG++ E + AIK K + +K R IL E I
Sbjct: 116 YTFGRILGKGSFGIVIEATDKETETKWAIKKVNKEKAGSSAVKLLEREVNILKSVKHEHI 175
Query: 134 PQAYYFGQEGLHNILVIDLLGPS-LEDLFDWCGRRFSIKTVVHVAIQMITLIEELHDHDL 192
+ LV++L L+++ D G FS + + + I LH++D+
Sbjct: 176 IHLEQVFETPKKMYLVMELCEDGELKEILDRKGH-FSENETRWIIQSLASAIAYLHNNDI 234
Query: 193 IYRDIKPDNFLIGRPNQPDANMVHL----IDFGMAKLYRDPKTKQHIPYREKKSLSGTAR 248
++RD+K +N ++ D N ++L DFG+A KQ ++ GT
Sbjct: 235 VHRDLKLENIMVKSSLIDDNNEINLNIKVTDFGLA------VKKQSRSEAMLQATCGTPI 288
Query: 249 YMSINTHLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKAANNKL 293
YM+ + S++ D+ ++G V + LRG+ P+ L ++ KL
Sbjct: 289 YMAPEVISAHDYSQQCDIWSIGVVMYMLLRGEPPF--LASSEEKL 331
>CE24761 [D] KOG0580 Serine/threonine protein kinase
Length = 305
Score = 56.2 bits (134), Expect = 1e-07
Identities = 52/214 (24%), Positives = 97/214 (45%), Gaps = 22/214 (10%)
Query: 77 YKIGKKIGEGSFGVLFEGVNMINNVPVAIK--FEPRKTDAP---QLKDEYRTYKILSGSE 131
++IG+ +G+G FG ++ + VAIK F+ + QL+ E L+
Sbjct: 30 FEIGRPLGKGKFGSVYLARTKTGHFHVAIKVLFKSQLISGGVEHQLEREIEIQSHLNHPN 89
Query: 132 GIP-QAYYFGQEGLHNILVIDLLGPSLEDLFDWCGRRFSIKTVVHVAIQMITLIEELHDH 190
I Y++ + ++ +L G + L +RFS T ++ + H
Sbjct: 90 IIKLYTYFWDAKKIYLVLEYAPGGEMYKQLT--VSKRFSEPTAAKYMYEIADALSYCHRK 147
Query: 191 DLIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTARYM 250
++I+RDIKP+N LIG + + + DFG + H P +++++ GT Y+
Sbjct: 148 NVIHRDIKPENLLIGSQGE-----LKIGDFGWS---------VHAPSNKRQTMCGTMDYL 193
Query: 251 SINTHLGREQSRRDDMEALGHVFFYFLRGQLPWQ 284
G + S D+ A+G + + FL G+ P++
Sbjct: 194 PPEMVNGADHSDAVDLWAIGVLCYEFLVGKPPFE 227
>7302570 [R] KOG0586 Serine/threonine protein kinase
Length = 702
Score = 56.2 bits (134), Expect = 1e-07
Identities = 54/219 (24%), Positives = 98/219 (44%), Gaps = 27/219 (12%)
Query: 76 HYKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPRKTDAPQLKDEY--RTYKILSGSEGI 133
+Y++ K IG+G+F V+ N++ VAIK D L +EY +T++ ++ + +
Sbjct: 40 YYELEKTIGKGNFAVVKLATNIVTKTKVAIKI----IDKTCLNEEYLNKTFREIAILKSL 95
Query: 134 PQAY----YFGQEGLHNILVIDLLGPSLEDLFDW--CGRRFSIKTVVHVAIQMITLIEEL 187
+ Y E I ++ P+ E +FD R V Q+++ +
Sbjct: 96 RHPHITRLYEVMESQSMIYLVTEYAPNGE-IFDHLVANGRMKEPEAARVFTQLVSAVHYC 154
Query: 188 HDHDLIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTA 247
H +++RD+K +N L+ + D N + L DFG + Y + T K+ G+
Sbjct: 155 HRRGVVHRDLKAENVLLDK----DMN-IKLADFGFSNHYEEGAT--------LKTWCGSP 201
Query: 248 RYMSINTHLGRE-QSRRDDMEALGHVFFYFLRGQLPWQG 285
Y + G E + D+ +LG V + + G LP+ G
Sbjct: 202 PYAAPEVFQGLEYDGPKSDIWSLGVVLYALVCGALPFDG 240
>7300559 [T] KOG4279 Serine/threonine protein kinase
Length = 1310
Score = 56.2 bits (134), Expect = 1e-07
Identities = 44/175 (25%), Positives = 83/175 (47%), Gaps = 19/175 (10%)
Query: 83 IGEGSFGVLFEGVNMINNVPVAIKFEPRKT--DAPQLKDEYRTYKILSGSEGIPQAYYFG 140
+G+G++G ++ + V +AIK P K D L +E + + L +
Sbjct: 585 LGKGTYGTVYAARDKQTQVRIAIKEVPEKNSQDVQPLHEEIKLHSQLRHRNIVRYLGSCS 644
Query: 141 QEGLHNILVIDLLGPSLEDLFD--WCGRRFSIKTVVHVAIQMITLIEELHDHDLIYRDIK 198
+ G I + + G SL DL + W + + T+ + Q++ ++ LH+ D+++RDIK
Sbjct: 645 ENGFFKIFMEQVPGGSLSDLLETKWGPLKDNESTMAFYSKQILEGLKYLHEQDIVHRDIK 704
Query: 199 PDNFLIGRPNQPDANMVHLIDFGMAKLYR--DPKTKQHIPYREKKSLSGTARYMS 251
DN L+ + +V + DFG +K +P T ++ +GT +YM+
Sbjct: 705 GDNVLV----NTYSGVVKISDFGTSKRLARINPMT---------ETFTGTLQYMA 746
>Hs18552621 [R] KOG0597 Serine-threonine protein kinase FUSED
Length = 1315
Score = 55.8 bits (133), Expect = 2e-07
Identities = 53/210 (25%), Positives = 92/210 (43%), Gaps = 16/210 (7%)
Query: 77 YKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPRK-TDAPQLKDEYRTYKILSGSE--GI 133
Y + + IGEGSFG +++G + VA+KF P+ +L++ R +I+ G I
Sbjct: 4 YHVLEMIGEGSFGRVYKGRRKYSAQVVALKFIPKLGRSEKELRNLQREIEIMRGLRHPNI 63
Query: 134 PQAYYFGQEGLHNILVIDLLGPSLEDLFDWCGRRFSIKTVVHVAIQMITLIEELHDHDLI 193
+ ++V D L + + G+ V +A Q+++ + LH H ++
Sbjct: 64 VHMLDSFETDKEVVVVTDYAEGELFQILEDDGK-LPEDQVQAIAAQLVSALYYLHSHRIL 122
Query: 194 YRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTARYMSIN 253
+RD+KP N L+ + + L DFG A R T + S+ GT YMS
Sbjct: 123 HRDMKPQNILLAK-----GGGIKLCDFGFA---RAMSTNTMV----LTSIKGTPLYMSPE 170
Query: 254 THLGREQSRRDDMEALGHVFFYFLRGQLPW 283
R D+ ++G + + G P+
Sbjct: 171 LVEERPYDHTADLWSVGCILYELAVGTPPF 200
>ECU07g0360 [D] KOG0580 Serine/threonine protein kinase
Length = 272
Score = 55.8 bits (133), Expect = 2e-07
Identities = 55/232 (23%), Positives = 103/232 (43%), Gaps = 22/232 (9%)
Query: 77 YKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPRKT-----DAPQLKDEYRTYKILSGSE 131
++IG+ +G G FG ++ VA+K P K A Q++ E + L
Sbjct: 10 FEIGRLLGRGKFGQVWLAREREKGFIVALKIIPIKEIQTVETARQIRREIEIHSNLKHPN 69
Query: 132 GIPQ-AYYFGQEGLHNILVIDLLGPSLEDLFDWCGRRFSIKTVVHVAIQMITLIEELHDH 190
+ ++ ++ ++ IL G + L D G+ +T +++ Q++ + + +
Sbjct: 70 ILRMYGHFHDKDNIYLILEYAGKGEFFKFLSDRGGKFGEKETSLYIR-QVMLALTYMKEC 128
Query: 191 DLIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTARYM 250
++I+RDIKP+N L+G NQ + + DFG A D + + + GT Y+
Sbjct: 129 NVIHRDIKPENLLLGSDNQ-----LKIADFGWAVYNAD---------KRRMTFCGTMEYL 174
Query: 251 SINTHLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKAANNKLKYEKIGEKK 302
+ D+ LG + + FL G+ P++ K N + Y+KI K
Sbjct: 175 APEMVNNDIHDSGIDLWCLGILTYEFLMGKTPFES-KNRNMREAYKKINSLK 225
>At4g23650 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 529
Score = 55.8 bits (133), Expect = 2e-07
Identities = 55/220 (25%), Positives = 100/220 (45%), Gaps = 28/220 (12%)
Query: 77 YKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEP-----RKTDAPQLKDEYRTYKILSGSE 131
Y+ G+++G G FGV + + VA K P K D ++ E + LSG
Sbjct: 78 YEFGRELGRGQFGVTYLVTHKETKQQVACKSIPTRRLVHKDDIEDVRREVQIMHHLSGHR 137
Query: 132 GIPQ---AYYFGQEGLHNI-LVIDLLGPSLEDLFDWCGRR--FSIKTVVHVAIQMITLIE 185
I AY E H++ L+++L +LFD + +S + + QM+ ++
Sbjct: 138 NIVDLKGAY----EDRHSVNLIMELCEGG--ELFDRIISKGLYSERAAADLCRQMVMVVH 191
Query: 186 ELHDHDLIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSG 245
H +++RD+KP+NFL ++ + + + DFG++ ++ P + K L G
Sbjct: 192 SCHSMGVMHRDLKPENFLF--LSKDENSPLKATDFGLSVFFK--------PGDKFKDLVG 241
Query: 246 TARYMSINTHLGREQSRRDDMEALGHVFFYFLRGQLPWQG 285
+A Y++ L R D+ + G + + L G P+ G
Sbjct: 242 SAYYVAPEV-LKRNYGPEADIWSAGVILYILLSGVPPFWG 280
>At3g27560 [T] KOG0192 Tyrosine kinase specific for activated (GTP-bound)
p21cdc42Hs
Length = 356
Score = 55.8 bits (133), Expect = 2e-07
Identities = 55/220 (25%), Positives = 96/220 (43%), Gaps = 17/220 (7%)
Query: 76 HYKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPRKTDAPQLKDE----YRTYKILSGSE 131
H +G KIGEG+ ++EG N VAIK R ++ R +LS +
Sbjct: 25 HLFVGPKIGEGAHAKVYEG--KYRNQTVAIKIIKRGESPEEIAKRDNRFAREIAMLSKVQ 82
Query: 132 GIPQAYYFG--QEGLHNILVIDLLGPSLED-LFDWCGRRFSIKTVVHVAIQMITLIEELH 188
+ G +E + I+ LLG +L L +R I+ V A+ + +E LH
Sbjct: 83 HKNLVKFIGACKEPMMVIVTELLLGGTLRKYLVSLRPKRLDIRLAVGFALDIARAMECLH 142
Query: 189 DHDLIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTAR 248
H +I+RD+KP+N ++ D V L DFG+A+ + T+
Sbjct: 143 SHGIIHRDLKPENLIL----SADHKTVKLADFGLAR--EESLTEMMTAETGTYRWMAPEL 196
Query: 249 YMSINTHLGREQ--SRRDDMEALGHVFFYFLRGQLPWQGL 286
Y ++ G ++ + + D + V + + +LP++G+
Sbjct: 197 YSTVTLRQGEKKHYNHKVDAYSFAIVLWELILNKLPFEGM 236
>At3g06030 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 651
Score = 55.8 bits (133), Expect = 2e-07
Identities = 53/219 (24%), Positives = 97/219 (44%), Gaps = 21/219 (9%)
Query: 75 LHYKIGKKIGEGSFGVLFEGVNMINNVPVAIKF----------EPRKTDAPQLKDEYRTY 124
+ ++ G+ IG G+FG ++ G+N+ + +AIK E + +L++E +
Sbjct: 66 IRWRKGELIGCGAFGRVYMGMNLDSGELLAIKQVLIAPSSASKEKTQGHIRELEEEVQLL 125
Query: 125 KILSGSEGIPQAYYFGQEGLHNILVIDLLGPSLEDLFDWCGRRFSIKTVVHVAIQMITLI 184
K LS + + NIL+ + G S+ L + G F ++ Q++ +
Sbjct: 126 KNLSHPNIVRYLGTVRESDSLNILMEFVPGGSISSLLEKFGS-FPEPVIIMYTKQLLLGL 184
Query: 185 EELHDHDLIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLS 244
E LH++ +++RDIK N L+ + + L DFG +K K + KS+
Sbjct: 185 EYLHNNGIMHRDIKGANILV-----DNKGCIRLADFGASK-----KVVELATVNGAKSMK 234
Query: 245 GTARYMSINTHLGREQSRRDDMEALGHVFFYFLRGQLPW 283
GT +M+ L S D+ ++G G+ PW
Sbjct: 235 GTPYWMAPEVILQTGHSFSADIWSVGCTVIEMATGKPPW 273
>At2g31500 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 582
Score = 55.8 bits (133), Expect = 2e-07
Identities = 54/218 (24%), Positives = 99/218 (44%), Gaps = 20/218 (9%)
Query: 73 VGLHYKIGKKIGEGSFGVLFEGVNMINNVPVAIKF---EPRKTDAPQLKDEYRTYKILSG 129
+ L Y +GK++G G FGV E + + A K E +T+ ++D R +I+
Sbjct: 62 IHLKYDLGKELGRGEFGVTHECIEISTRERFACKRISKEKLRTEI-DVEDVRREVEIMRC 120
Query: 130 SEGIPQAYYFGQEGLHNILVIDLLGPSLE--DLFDWCGRR--FSIKTVVHVAIQMITLIE 185
P F +E + + L+ E +LFD R ++ + VA ++ +++
Sbjct: 121 LPKHPNIVSF-KEAFEDKDAVYLVMEICEGGELFDRIVSRGHYTERAAASVAKTILEVVK 179
Query: 186 ELHDHDLIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSG 245
H+H +I+RD+KP+NFL N + + IDFG++ ++ P + + G
Sbjct: 180 VCHEHGVIHRDLKPENFLFS--NGTETAQLKAIDFGLSIFFK--------PAQRFNEIVG 229
Query: 246 TARYMSINTHLGREQSRRDDMEALGHVFFYFLRGQLPW 283
+ YM+ L R D+ + G + + L G P+
Sbjct: 230 SPYYMAPEV-LRRNYGPEIDVWSAGVILYILLCGVPPF 266
>At1g61950 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 547
Score = 55.8 bits (133), Expect = 2e-07
Identities = 50/216 (23%), Positives = 101/216 (46%), Gaps = 23/216 (10%)
Query: 77 YKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPRKT-----DAPQLKDEYRTYKILSGSE 131
Y +G+++G G FG+ + + + A K ++ D ++ E + LSG
Sbjct: 98 YSLGRELGRGQFGITYICTEISSGKNFACKSILKRKLIRTKDREDVRREIQIMHYLSGQP 157
Query: 132 GIPQ--AYYFGQEGLHNILVIDLLGPSLEDLFDWCGRR--FSIKTVVHVAIQMITLIEEL 187
I + Y ++ +H LV++L +LFD +R +S K + ++ +++
Sbjct: 158 NIVEIKGAYEDRQSVH--LVMELCEGG--ELFDKITKRGHYSEKAAAEIIRSVVKVVQIC 213
Query: 188 HDHDLIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTA 247
H +I+RD+KP+NFL+ ++ ++M+ DFG++ + K + I G+A
Sbjct: 214 HFMGVIHRDLKPENFLLSSKDEA-SSMLKATDFGVSVFIEEGKVYEDI--------VGSA 264
Query: 248 RYMSINTHLGREQSRRDDMEALGHVFFYFLRGQLPW 283
Y++ L R + D+ + G + + L G P+
Sbjct: 265 YYVAPEV-LKRNYGKAIDIWSAGVILYILLCGNPPF 299
>At3g61960 [OUT] KOG0595 Serine/threonine-protein kinase involved in autophagy
Length = 648
Score = 55.5 bits (132), Expect = 2e-07
Identities = 51/214 (23%), Positives = 98/214 (44%), Gaps = 17/214 (7%)
Query: 77 YKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPRKTDAPQLKDE-YRTYKILSGSE--GI 133
Y +G +IG GSF V++ + + + VA+K +K +P+++D + ILS + I
Sbjct: 10 YALGPRIGSGSFAVVWLAKHRSSGLEVAVKEIDKKLLSPKVRDNLLKEISILSTIDHPNI 69
Query: 134 PQAYYFGQEGLHNILVIDLLGPSLEDLFDWCGRRFSIKTVV--HVAIQMITLIEELHDHD 191
+ Y + G LV++ S DL + R + V H Q+ ++ L +
Sbjct: 70 IRFYEAIETGDRIFLVLEYC--SGGDLAGYINRHGKVPEAVAKHFMRQLALGLQVLQEKH 127
Query: 192 LIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTARYMS 251
I+RD+KP N L+ ++ ++ + DFG A + P ++ G+ YM+
Sbjct: 128 FIHRDLKPQNLLLS--SKEVTPLLKIGDFGFA--------RSLTPESMAETFCGSPLYMA 177
Query: 252 INTHLGREQSRRDDMEALGHVFFYFLRGQLPWQG 285
++ + D+ + G + F + G+ P+ G
Sbjct: 178 PEIIRNQKYDAKADLWSAGAILFQLVTGKPPFDG 211
>At2g35890 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 520
Score = 55.5 bits (132), Expect = 2e-07
Identities = 49/217 (22%), Positives = 93/217 (42%), Gaps = 20/217 (9%)
Query: 76 HYKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPRKT-----DAPQLKDEYRTYKILSGS 130
+Y +G K+G G FG F V A K P++ D ++ E K L G
Sbjct: 131 YYNLGSKLGHGQFGTTFVCVEKGTGEEYACKSIPKRKLENEEDVEDVRREIEIMKHLLGQ 190
Query: 131 EGIPQAYYFGQEGLHNILVIDLLGPSLEDLFDWCGRR--FSIKTVVHVAIQMITLIEELH 188
+ ++ + +V++L +LFD R +S + H+A ++ +++ H
Sbjct: 191 PNVISIKGAYEDSVAVHMVMELCRGG--ELFDRIVERGHYSERKAAHLAKVILGVVQTCH 248
Query: 189 DHDLIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTAR 248
+++RD+KP+NFL N + + + IDFG++ + P + G+
Sbjct: 249 SLGVMHRDLKPENFLF--VNDDEDSPLKAIDFGLSMFLK--------PGENFTDVVGSPY 298
Query: 249 YMSINTHLGREQSRRDDMEALGHVFFYFLRGQLPWQG 285
Y++ L + D+ + G + + L G P+ G
Sbjct: 299 YIAPEV-LNKNYGPEADIWSAGVMIYVLLSGSAPFWG 334
>YOR061w [TDK] KOG0668 Casein kinase II alpha subunit
Length = 339
Score = 55.1 bits (131), Expect = 3e-07
Identities = 46/159 (28%), Positives = 77/159 (47%), Gaps = 22/159 (13%)
Query: 76 HYKIGKKIGEGSFGVLFEGVNMINNVPVAIK-FEPRKTDAPQLKDEYRTYKILSGSEGIP 134
+Y+I KIG G + +F G ++NN IK +P K +K YR KIL+ G P
Sbjct: 49 NYEIINKIGRGKYSEVFSGRCIVNNQKCVIKVLKPVK-----MKKIYRELKILTNLTGGP 103
Query: 135 QAYYFGQEGLHNILV-IDLLGPSL--EDL----FDWCGRRFSIKTVVHVAIQMITLIEEL 187
GL++I+ D P+L E++ F F + + + Q++ ++
Sbjct: 104 NVV-----GLYDIVQDADSKIPALIFEEIKNVDFRTLYPTFKLPDIQYYFTQLLIALDYC 158
Query: 188 HDHDLIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLY 226
H +++RD+KP N +I P + LID+G+A+ Y
Sbjct: 159 HSMGIMHRDVKPQNVMI----DPTERKLRLIDWGLAEFY 193
>SPBC8D2.19 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 559
Score = 55.1 bits (131), Expect = 3e-07
Identities = 49/171 (28%), Positives = 86/171 (49%), Gaps = 15/171 (8%)
Query: 77 YKIGKKIGEGSFGVLFEGVNMINN---VPVAIK-----FEPR-KTDAPQLKDEYRTYKIL 127
Y + +K+G+GSFG ++ N VA+K +P+ K + +L++ KI
Sbjct: 21 YLVKQKLGDGSFGTVYLAQRKEKNGLYETVAVKKLKNSSKPKPKHELLKLRESLALRKIS 80
Query: 128 SGSEGIPQAYYFGQEGLHNILVIDLLGPSLEDLFDWC-GRRFSIKTVVHVAIQMITLIEE 186
I F + LV++ + +L LF GR F+ +T ++ +Q+I+ IE
Sbjct: 81 KHPCLIDLLETFMDPYRNIFLVMEFMDCNLFQLFKRRQGRLFTKETAFNILLQIISGIEH 140
Query: 187 LHDHDLIYRDIKPDNFLIGRPNQPDAN---MVHLIDFGMAK--LYRDPKTK 232
+H H ++RDIKP+N L+ R + + + L DFG+A+ + DP T+
Sbjct: 141 IHKHGFMHRDIKPENILVKRISPKPISSRYSIKLGDFGLARPSVSSDPLTE 191
>Hs22068996 [T] KOG1345 Serine/threonine kinase
Length = 380
Score = 55.1 bits (131), Expect = 3e-07
Identities = 64/254 (25%), Positives = 109/254 (42%), Gaps = 25/254 (9%)
Query: 76 HYKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPR-KTDAPQLKDEYRTYKILSGSEGIP 134
HY++ +++G+G++G + V +A+KF + KT E LS S I
Sbjct: 52 HYELVRELGKGTYGKVDLVVYKGTGTKMALKFVNKSKTKLKNFLREVSITNSLSSSPFII 111
Query: 135 QAYYFGQEGLHNILVIDLLGPSLEDLFDWCGRRFSIK--TVVHVAIQMITLIEELHDHDL 192
+ + E + P+ DLFD + + TV Q+ ++ +H L
Sbjct: 112 KVFDVVFETEDCYVFAQEYAPA-GDLFDIIPPQVGLPEDTVKRCVQQLGLALDFMHGRQL 170
Query: 193 IYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLY--RDPKTKQHIPYREKK-SLSGTARY 249
++RDIKP+N L+ + V L DFGM + R + IPY + +G A
Sbjct: 171 VHRDIKPENVLL---FDRECRRVKLADFGMTRRVGCRVKRVSGTIPYTAPEVCQAGRADG 227
Query: 250 MSINTHLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKAANNKLKYEKIGEKKRSTNVYD 309
++++T + D+ A G + F L G PW+ A+ +E+ +R
Sbjct: 228 LAVDTGV--------DVWAFGVLIFCVLTGNFPWEAASGAD--AFFEEFVRWQRGR---- 273
Query: 310 LSQGLPVQFGRYLE 323
GLP Q+ R+ E
Sbjct: 274 -LPGLPSQWRRFTE 286
>7298698 [T] KOG4250 TANK binding protein kinase TBK1
Length = 711
Score = 55.1 bits (131), Expect = 3e-07
Identities = 62/257 (24%), Positives = 115/257 (44%), Gaps = 26/257 (10%)
Query: 83 IGEGSFGVLFEGVNMINNVPVAIK-FEPRKTDAP---QLKDEYRTYKILSGSEGIPQAYY 138
+G+G+ G +F+GVN I VA+K F P P Q+++ K+ + A
Sbjct: 18 LGKGATGSVFQGVNKITGESVAVKTFNPYSHMRPADVQMREFEALKKVNHENIVKLLAIE 77
Query: 139 FGQEGLHNILVIDL-LGPSLEDLFDWCGRRFSI--KTVVHVAIQMITLIEELHDHDLIYR 195
QEG ++V++L G SL ++ D + + + V + ++ L D+ L++R
Sbjct: 78 EDQEGRGKVIVMELCTGGSLFNILDDPENSYGLPEHEFLLVLEHLCAGMKHLRDNKLVHR 137
Query: 196 DIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTARYMS---- 251
D+KP N ++ ++ + L DFG A+ D + P+ SL GT Y+
Sbjct: 138 DLKPGN-IMKFISEDGQTIYKLTDFGAARELEDNQ-----PF---ASLYGTEEYLHPDLY 188
Query: 252 ----INTHLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKAANNKLKYEKIGEKKRSTNV 307
+ + R + D+ ++G ++ G LP++ N+ +I KK S +
Sbjct: 189 ERAVLRKSIQRSFTANVDLWSIGVTLYHVATGNLPFRPFGGRKNRETMHQITTKKASGVI 248
Query: 308 --YDLSQGLPVQFGRYL 322
LS+ P+++ L
Sbjct: 249 SGTQLSENGPIEWSTTL 265
>Hs4506735 [T] KOG0603 Ribosomal protein S6 kinase
Length = 772
Score = 54.7 bits (130), Expect = 3e-07
Identities = 50/208 (24%), Positives = 91/208 (43%), Gaps = 18/208 (8%)
Query: 83 IGEGSFGVLFEGVNMINNVPVAIKFEPRKTDAPQLKDEYRTYKILSGSEGIPQAYYFGQE 142
+G+GSF V + A+K R+ +A + E ++ + + +
Sbjct: 417 LGQGSFSVCRRCRQRQSGQEFAVKILSRRLEA-NTQREVAALRLCQSHPNVVNLHEVHHD 475
Query: 143 GLHNILVIDLL--GPSLEDLFDWCGRRFSIKTVVHVAIQMITLIEELHDH-DLIYRDIKP 199
LH LV++LL G LE + R FS + +++ + +H+ +++RD+KP
Sbjct: 476 QLHTYLVLELLRGGELLEHIRK--KRHFSESEASQILRSLVSAVSFMHEEAGVVHRDLKP 533
Query: 200 DNFLIG--RPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTARYMSINTHLG 257
+N L P P V +IDFG A+L + P ++ T +Y +
Sbjct: 534 ENILYADDTPGAP----VKIIDFGFARL------RPQSPGVPMQTPCFTLQYAAPELLAQ 583
Query: 258 REQSRRDDMEALGHVFFYFLRGQLPWQG 285
+ D+ +LG + + L GQ+P+QG
Sbjct: 584 QGYDESCDLWSLGVILYMMLSGQVPFQG 611
>ECU07g0520 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 322
Score = 54.7 bits (130), Expect = 3e-07
Identities = 48/177 (27%), Positives = 77/177 (43%), Gaps = 21/177 (11%)
Query: 110 RKTDAPQLKDEYRTYKILSGSEGIPQAYYFGQEGLHNILVIDLLGPSLEDLFDW---CGR 166
R+ A QL++E K + G + + Y G L+++ +G +LF W CGR
Sbjct: 46 RQRLADQLENEISILKRIYGCPFVAKLYSTDFHGGKVGLIMEYVGGG--ELFYWLKKCGR 103
Query: 167 RFSIKTVVHVAIQMITLIEELHDHDLIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLY 226
F + A ++I+ + +H ++YRD+KP+N LI + LIDFG + +Y
Sbjct: 104 -FDEQMARFYAAEIISALRFIHGRGILYRDLKPENILI-----TSTGHIKLIDFGFS-VY 156
Query: 227 RDPKTKQHIPYREKKSLSGTARYMSINTHLGREQSRRDDMEALGHVFFYFLRGQLPW 283
+SGT YMS + R D LG + + L G P+
Sbjct: 157 ESENIYM---------ISGTPEYMSPEKLRSEDDGRASDYWGLGVMIYEMLCGDPPF 204
>At4g04720 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 531
Score = 54.7 bits (130), Expect = 3e-07
Identities = 51/216 (23%), Positives = 100/216 (45%), Gaps = 24/216 (11%)
Query: 77 YKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPR-----KTDAPQLKDEYRTYKILSGSE 131
Y +GK++G G FG+ + + A K + K D +K E + + LSG
Sbjct: 80 YSLGKELGRGQFGITYMCKEIGTGNTYACKSILKRKLISKQDKEDVKREIQIMQYLSGQP 139
Query: 132 GIPQ--AYYFGQEGLHNILVIDLLGPSLEDLFDW--CGRRFSIKTVVHVAIQMITLIEEL 187
I + Y ++ +H LV++L +LFD +S + + ++ +++
Sbjct: 140 NIVEIKGAYEDRQSIH--LVMELCAGG--ELFDRIIAQGHYSERAAAGIIRSIVNVVQIC 195
Query: 188 HDHDLIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTA 247
H +++RD+KP+NFL+ ++ + M+ DFG++ + K YR+ + G+A
Sbjct: 196 HFMGVVHRDLKPENFLLS--SKEENAMLKATDFGLSVFIEEGKV-----YRD---IVGSA 245
Query: 248 RYMSINTHLGREQSRRDDMEALGHVFFYFLRGQLPW 283
Y++ L R + D+ + G + + L G P+
Sbjct: 246 YYVAPEV-LRRSYGKEIDIWSAGVILYILLSGVPPF 280
>At3g20410 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 541
Score = 54.7 bits (130), Expect = 3e-07
Identities = 51/218 (23%), Positives = 100/218 (45%), Gaps = 20/218 (9%)
Query: 73 VGLHYKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPRK-----TDAPQLKDEYRTYKIL 127
V L Y +GK++G G FGV + A K +K D ++ E + + L
Sbjct: 87 VKLFYTLGKELGRGQFGVTYLCTENSTGKKYACKSISKKKLVTKADKDDMRREIQIMQHL 146
Query: 128 SGSEGIPQAYYFGQEGLHNILVIDLLGPSLEDLFDWCGRR--FSIKTVVHVAIQMITLIE 185
SG I + ++ LV++L +LFD + ++ + V Q++ +++
Sbjct: 147 SGQPNIVEFKGAYEDEKAVNLVMELCAGG--ELFDRIIAKGHYTERAAASVCRQIVNVVK 204
Query: 186 ELHDHDLIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSG 245
H +++RD+KP+NFL+ ++ + ++ DFG++ + K YR+ + G
Sbjct: 205 ICHFMGVLHRDLKPENFLLS--SKDEKALIKATDFGLSVFIEEGKV-----YRD---IVG 254
Query: 246 TARYMSINTHLGREQSRRDDMEALGHVFFYFLRGQLPW 283
+A Y++ L R + D+ + G + + L G P+
Sbjct: 255 SAYYVAPEV-LRRRYGKEVDIWSAGIILYILLSGVPPF 291
>At2g38910 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 583
Score = 54.7 bits (130), Expect = 3e-07
Identities = 54/216 (25%), Positives = 98/216 (45%), Gaps = 24/216 (11%)
Query: 77 YKIGKKIGEGSFGVLFEGVNMINNVPVAIK-FEPRKTDAPQ-LKDEYRTYKILSGSEGIP 134
Y +G+K+G+G FG F V+ A K RK P+ ++D R +I+ G P
Sbjct: 134 YSVGRKLGQGQFGTTFLCVDKKTGKEFACKTIAKRKLTTPEDVEDVRREIQIMHHLSGHP 193
Query: 135 QAY-----YFGQEGLHNILVIDLLGPSLEDLFDWCGRR--FSIKTVVHVAIQMITLIEEL 187
Y +H ++ I G +LFD +R ++ K +A ++ +IE
Sbjct: 194 NVIQIVGAYEDAVAVHVVMEICAGG----ELFDRIIQRGHYTEKKAAELARIIVGVIEAC 249
Query: 188 HDHDLIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTA 247
H +++RD+KP+NFL ++ A + IDFG++ ++ +T + G+
Sbjct: 250 HSLGVMHRDLKPENFLFVSGDEEAA--LKTIDFGLSVFFKPGETFTDV--------VGSP 299
Query: 248 RYMSINTHLGREQSRRDDMEALGHVFFYFLRGQLPW 283
Y++ L + S D+ + G + + L G P+
Sbjct: 300 YYVAPEV-LRKHYSHECDVWSAGVIIYILLSGVPPF 334
>YHR205w [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 824
Score = 54.3 bits (129), Expect = 5e-07
Identities = 40/134 (29%), Positives = 63/134 (46%), Gaps = 20/134 (14%)
Query: 167 RFSIKTVVHVAIQMITLIEELHDHDLIYRDIKPDNFLIGRPNQPDAN-MVHLIDFGMAKL 225
RFS +++ +E LHD+D++YRD+KP+N L+ DAN + L DFG++K
Sbjct: 509 RFSEDRAKFYIAELVLALEHLHDNDIVYRDLKPENILL------DANGNIALCDFGLSKA 562
Query: 226 YRDPKTKQHIPYREKKSLSGTARYMSINTHLGRE-QSRRDDMEALGHVFFYFLRGQLPWQ 284
+T + GT Y++ L ++ D +LG + F G W
Sbjct: 563 DLKDRT---------NTFCGTTEYLAPELLLDETGYTKMVDFWSLGVLIFEMCCG---WS 610
Query: 285 GLKAANNKLKYEKI 298
A NN+ Y+KI
Sbjct: 611 PFFAENNQKMYQKI 624
>Hs4826948 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 358
Score = 54.3 bits (129), Expect = 5e-07
Identities = 37/117 (31%), Positives = 54/117 (45%), Gaps = 15/117 (12%)
Query: 167 RFSIKTVVHVAIQMITLIEELHDHDLIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLY 226
RFS T + + ++I IE LH +++YRD+KP+N L+ R + L DFG AK
Sbjct: 143 RFSSTTGLFYSAEIICAIEYLHSKEIVYRDLKPENILLDRDGH-----IKLTDFGFAKKL 197
Query: 227 RDPKTKQHIPYREKKSLSGTARYMSINTHLGREQSRRDDMEALGHVFFYFLRGQLPW 283
D +L GT Y++ + R D ALG + F L G P+
Sbjct: 198 VD----------RTWTLCGTPEYLAPEVIQSKGHGRAVDWWALGILIFEMLSGFPPF 244
>At2g34290 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 265
Score = 54.3 bits (129), Expect = 5e-07
Identities = 64/218 (29%), Positives = 95/218 (43%), Gaps = 30/218 (13%)
Query: 83 IGEGSFGVL----FEGVNMINNVPVAIKFEPRKTDAPQLKDEYRTYKILSGSEGIPQAYY 138
+GEGSFG + ++ + + A+K DA L +E++ G I Q Y
Sbjct: 7 LGEGSFGSVSLFSYKRRCDVETLYAAVK---TSDDAKSLYEEFQILSKFKGCSRIVQCYG 63
Query: 139 FGQEGLHN--------ILVIDLLGPSLEDLFDWCGRRFSIKTVVHVAIQMIT--LIEEL- 187
G E N I + G SL D D RF+ K + I+ T L+E L
Sbjct: 64 SGVEQRLNDKGYVEYTIPMEYAAGGSLSDFMD----RFNDKKLPDPMIRKFTRMLLEGLA 119
Query: 188 --HDHDLIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSG 245
H H ++ D+KP+N L+ + D + + DFG++K RD T P KS +G
Sbjct: 120 TIHRHGYVHCDLKPENILVFPGSVCDLKL-KISDFGLSK--RDGDTTWWHPL---KSYAG 173
Query: 246 TARYMSINTHLGREQSRRDDMEALGHVFFYFLRGQLPW 283
T YMS + E + D+ +LG V G+ PW
Sbjct: 174 TPIYMSPESISHGEIGKGLDLWSLGCVVLEMYTGKRPW 211
>At5g55090 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 448
Score = 53.9 bits (128), Expect = 6e-07
Identities = 39/143 (27%), Positives = 60/143 (41%), Gaps = 15/143 (10%)
Query: 144 LHNILVIDLLGPSLEDLFDWCGRRFSIKTVVHVAIQMITLIEELHDHDLIYRDIKPDNFL 203
++N+L+ + G SL DL G + + Q++ + LHD +++ D+K N +
Sbjct: 75 MYNLLMEYVSGGSLHDLIKNSGGKLPEPLIRSYTRQILKGLMYLHDQGIVHCDVKSQNVM 134
Query: 204 IGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTARYMSINTHLGREQSRR 263
IG + ++D G AK + E SGT +MS G EQS
Sbjct: 135 IG------GEIAKIVDLGCAKTVEE---------NENLEFSGTPAFMSPEVARGEEQSFP 179
Query: 264 DDMEALGHVFFYFLRGQLPWQGL 286
D+ ALG G PW L
Sbjct: 180 ADVWALGCTVIEMATGSSPWPEL 202
>At4g35780 [T] KOG0192 Tyrosine kinase specific for activated (GTP-bound)
p21cdc42Hs
Length = 553
Score = 53.9 bits (128), Expect = 6e-07
Identities = 51/212 (24%), Positives = 98/212 (46%), Gaps = 17/212 (8%)
Query: 78 KIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPRKTDAPQLKDEYRTYKILSGSEGIPQAY 137
KI KK+ GS+G LF G V + I +P + +A L++ + I+
Sbjct: 276 KIEKKVACGSYGELFRGTYCSQEVAIKI-LKPERVNAEMLREFSQEVYIMRKVRHKNVVQ 334
Query: 138 YFGQEGLHNILVIDLLGPSLEDLFDWCGRR---FSIKTVVHVAIQMITLIEELHDHDLIY 194
+ G L I + ++D+ + F I++++ VA+ + + LH +++I+
Sbjct: 335 FIGACTRSPNLCIVTEFMTRGSIYDFLHKHKGVFKIQSLLKVALDVSKGMNYLHQNNIIH 394
Query: 195 RDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTARYMSINT 254
RD+K N L+ + +V + DFG+A++ +T+ + E +GT R+M+
Sbjct: 395 RDLKTANLLM-----DEHEVVKVADFGVARV----QTESGVMTAE----TGTYRWMAPEV 441
Query: 255 HLGREQSRRDDMEALGHVFFYFLRGQLPWQGL 286
+ R D+ + V + L G+LP+ L
Sbjct: 442 IEHKPYDHRADVFSYAIVLWELLTGELPYSYL 473
>7300435 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and related
serine/threonine protein kinases
Length = 1612
Score = 53.9 bits (128), Expect = 6e-07
Identities = 62/213 (29%), Positives = 96/213 (44%), Gaps = 20/213 (9%)
Query: 80 GKKIGEGSFGVLFEGVNMINNVPVAIK---FEPRKTDAPQLKDEYRTYKILSGSEGIPQA 136
G KIG+G FG ++ VN +A+K +P +T A LK+ KIL G +
Sbjct: 1326 GIKIGQGRFGKVYTAVNNNTGELMAMKEIAIQPGETRA--LKNVAEELKILEGIKHKNLV 1383
Query: 137 YYFGQEGLHNILVIDL---LGPSLEDLFDWCGRRFSIKTVVHVAIQMITLIEELHDHDLI 193
Y+G E L+I + +LE L + G T A Q+++ + ELH H ++
Sbjct: 1384 RYYGIEVHREELLIFMELCSEGTLESLVELTGNLPEALTRRFTA-QLLSGVSELHKHGIV 1442
Query: 194 YRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTARYMS-- 251
+RDIK N + +N + L DFG A + T +P E + GT YM+
Sbjct: 1443 HRDIKTANIFL----VDGSNSLKLGDFGSAVKIQAHTT---VP-GELQGYVGTQAYMAPE 1494
Query: 252 INTHLGRE-QSRRDDMEALGHVFFYFLRGQLPW 283
+ T + R D+ ++G V G+ PW
Sbjct: 1495 VFTKTNSDGHGRAADIWSVGCVVVEMASGKRPW 1527
>7298323 [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 514
Score = 53.9 bits (128), Expect = 6e-07
Identities = 50/214 (23%), Positives = 95/214 (44%), Gaps = 20/214 (9%)
Query: 77 YKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPRKTD---APQLKDEYRTYKILSGSEGI 133
+ + + +GEG++G + +N VA+K K A ++ E K+L +
Sbjct: 22 WTLAQTLGEGAYGEVKLLINRQTGEAVAMKMVDLKKHPDAANSVRKEVCIQKMLQDKHIL 81
Query: 134 PQAYYFGQEGLHNILVIDLLGPSLEDLFDWCGRRFSIKTVVHVA----IQMITLIEELHD 189
+FG+ ++ I L + +LFD G + H A Q+++ + LH
Sbjct: 82 R---FFGKRSQGSVEYIFLEYAAGGELFDRIGEEPDVGMPQHEAQRYFTQLLSGLNYLHQ 138
Query: 190 HDLIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTARY 249
+ +RD+KP+N L+ + + V + DFGMA ++R ++ + R GT Y
Sbjct: 139 RGIAHRDLKPENLLL-----DEHDNVKISDFGMATMFRCKGKERLLDKR-----CGTLPY 188
Query: 250 MSINTHLGREQSRRDDMEALGHVFFYFLRGQLPW 283
++ ++ D+ + G + L G+LPW
Sbjct: 189 VAPEVLQKAYHAQPADLWSCGVILVTMLAGELPW 222
>Hs8923754 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 414
Score = 53.5 bits (127), Expect = 8e-07
Identities = 55/219 (25%), Positives = 99/219 (45%), Gaps = 24/219 (10%)
Query: 76 HYKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPRKT--DAPQLKDEYRTYKILSGSEG- 132
H++I + IG+GSFG + A+K+ ++ + ++++ +R +I+ G E
Sbjct: 22 HFQILRAIGKGSFGKVCIVQKRDTKKMYAMKYMNKQKCIERDEVRNVFRELQIMQGLEHP 81
Query: 133 -IPQAYYFGQEGLHNILVIDLL-GPSLEDLFDWCGRRFSIKTVVHVAIQMITLIEELHDH 190
+ +Y Q+ +V+DLL G L F+ TV ++ +E L +
Sbjct: 82 FLVNLWYSFQDEEDMFMVVDLLLGGDLRYHLQQ-NVHFTEGTVKLYICELALALEYLQRY 140
Query: 191 DLIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTARYM 250
+I+RDIKPDN L+ + VH+ DF +A + + + S++GT YM
Sbjct: 141 HIIHRDIKPDNILL-----DEHGHVHITDFNIATVVKGAE--------RASSMAGTKPYM 187
Query: 251 S-----INTHLGREQSRRDDMEALGHVFFYFLRGQLPWQ 284
+ + G S D +LG + LRG P++
Sbjct: 188 APEVFQVYMDRGPGYSYPVDWWSLGITAYELLRGWRPYE 226
>Hs10835065 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 277
Score = 53.5 bits (127), Expect = 8e-07
Identities = 39/127 (30%), Positives = 58/127 (44%), Gaps = 17/127 (13%)
Query: 159 DLFDWCGRR--FSIKTVVHVAIQMITLIEELHDHDLIYRDIKPDNFLIGRPNQPDANMVH 216
+LF + R FS T + + ++I IE LH +++YRD+KP+N L+ R +
Sbjct: 133 ELFSYLRNRGHFSSTTGLFYSAEIICAIEYLHSKEIVYRDLKPENILLDRDGH-----IK 187
Query: 217 LIDFGMAKLYRDPKTKQHIPYREKKSLSGTARYMSINTHLGREQSRRDDMEALGHVFFYF 276
L DFG AK D +L GT Y++ + R D ALG + F
Sbjct: 188 LTDFGFAKKLVD----------RTWTLCGTPEYLAPEVIQSKGHGRAVDWWALGILIFEM 237
Query: 277 LRGQLPW 283
L G P+
Sbjct: 238 LSGFPPF 244
>CE17284 [T] KOG0583 Serine/threonine protein kinase
Length = 726
Score = 53.5 bits (127), Expect = 8e-07
Identities = 52/228 (22%), Positives = 103/228 (44%), Gaps = 21/228 (9%)
Query: 77 YKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPRKT---DAPQLKDEYRTYKILSGSEGI 133
Y + ++G G FG + +++ N VAIK +K D P+++ E + LS + I
Sbjct: 11 YAVHDELGSGGFGKVRLATHLLTNQKVAIKIIDKKQLGHDLPRVQTEMDALRNLS-HQNI 69
Query: 134 PQAYYFGQEGLHNILVIDLLGPSLEDLFDWCGR--RFSIKTVVHVAIQMITLIEELHDHD 191
+ Y++ + +V++ ++FD+ R R H Q+++ I +H
Sbjct: 70 CRLYHYIETEDKFFIVMEYCSGG--EMFDYIVRKERLEESEARHFFRQLVSAIAFVHSQG 127
Query: 192 LIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTARYMS 251
+RD+KP+N L+ + + LIDFG+ + +H + G+ Y +
Sbjct: 128 YAHRDLKPENLLL-----TEDLHLKLIDFGLCAKTEKGRIDKH----NLDTCCGSPAYAA 178
Query: 252 INTHLGRE-QSRRDDMEALGHVFFYFLRGQLPWQGLKAANNKLKYEKI 298
G + + D+ ++G + + L G LP++ N ++ Y+KI
Sbjct: 179 PELIQGLQYKGNEADVWSMGILLYTLLVGALPFED---DNMQIMYKKI 223
>CE12478 [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 484
Score = 53.5 bits (127), Expect = 8e-07
Identities = 50/216 (23%), Positives = 95/216 (43%), Gaps = 15/216 (6%)
Query: 77 YKIGKKIGEGSFGVLFEGVN-----MINNVPVAIKFEPRKTDAPQLKDEYRTYKILSGSE 131
Y++ K +G+GSFG + N M+ + + + ++ E + L+G E
Sbjct: 25 YEVLKPLGQGSFGQVALVSNRRYPEMLAALKRIVITGQDREYIDAIRKEITIQESLTGHE 84
Query: 132 GIPQAYYFGQEGLHNILVIDLLGPSLEDLFD--WCGRRFSIKTVVHVAIQMITLIEELHD 189
+ Q G+E + L DL++ G FS++ Q++ ++ LH
Sbjct: 85 NVIQV--LGKESDAQFCYMFLEYADGGDLYEKITSGCSFSLEEAHSYFKQLVNGLKFLHC 142
Query: 190 HDLIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTARY 249
D+ +RDIKP+N ++ + + + + DFG+A YR + R G+ Y
Sbjct: 143 RDVAHRDIKPENLMLTHSGKSEMRHLKIADFGLATWYRYKGAELIFEQR-----CGSVEY 197
Query: 250 MSINTHLGRE-QSRRDDMEALGHVFFYFLRGQLPWQ 284
++ + G + + + D+ + G V L QLPW+
Sbjct: 198 VAPEIYTGAQYRGPQIDIWSAGVVLLAMLTRQLPWE 233
>Hs8393810_1 [T] KOG0587 Traf2- and Nck-interacting kinase and related germinal
center kinase (GCK) family protein kinases
Length = 336
Score = 53.5 bits (127), Expect = 8e-07
Identities = 43/157 (27%), Positives = 82/157 (51%), Gaps = 15/157 (9%)
Query: 77 YKIGKKIGEGSFGVLFEGVNMINNVPVAIKF-EPRKTDAPQLKDEYRTYKILSGSEGIPQ 135
++I + IG+G++G +F+ +N N A+K +P +++ EY K LS + +
Sbjct: 21 WEITETIGKGTYGKVFKVLNKKNGQKAAVKILDPIHDIDEEIEAEYNILKALSDHPNVVR 80
Query: 136 AY--YFGQEGLHNI---LVIDLL-GPSLEDL---FDWCGRRFSIKTVVHVAIQMITLIEE 186
Y YF ++ ++ LV++L G S+ DL F G R S + ++ + + ++
Sbjct: 81 FYGIYFKKDKVNGDKLWLVLELCSGGSVTDLVKGFLKRGERMSEPLIAYILHEALMGLQH 140
Query: 187 LHDHDLIYRDIKPDNFLIGRPNQPDANMVHLIDFGMA 223
LH++ I+RD+K +N L+ V L+DFG++
Sbjct: 141 LHNNKTIHRDVKGNNILL-----TTEGGVKLVDFGVS 172
>Hs20544910_1 [T] KOG0587 Traf2- and Nck-interacting kinase and related germinal
center kinase (GCK) family protein kinases
Length = 336
Score = 53.5 bits (127), Expect = 8e-07
Identities = 43/157 (27%), Positives = 82/157 (51%), Gaps = 15/157 (9%)
Query: 77 YKIGKKIGEGSFGVLFEGVNMINNVPVAIKF-EPRKTDAPQLKDEYRTYKILSGSEGIPQ 135
++I + IG+G++G +F+ +N N A+K +P +++ EY K LS + +
Sbjct: 21 WEITETIGKGTYGKVFKVLNKKNGQKAAVKILDPIHDIDEEIEAEYNILKALSDHPNVVR 80
Query: 136 AY--YFGQEGLHNI---LVIDLL-GPSLEDL---FDWCGRRFSIKTVVHVAIQMITLIEE 186
Y YF ++ ++ LV++L G S+ DL F G R S + ++ + + ++
Sbjct: 81 FYGIYFKKDKVNGDKLWLVLELCSGGSVTDLVKGFLKRGERMSEPLIAYILHEALMGLQH 140
Query: 187 LHDHDLIYRDIKPDNFLIGRPNQPDANMVHLIDFGMA 223
LH++ I+RD+K +N L+ V L+DFG++
Sbjct: 141 LHNNKTIHRDVKGNNILL-----TTEGGVKLVDFGVS 172
>SPBC106.10 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 512
Score = 53.1 bits (126), Expect = 1e-06
Identities = 61/226 (26%), Positives = 99/226 (42%), Gaps = 25/226 (11%)
Query: 83 IGEGSFGVLFEGVNMINNVPVAIKFEPRK--TDAPQLKDEYRTYKILSGSEGIPQAYYFG 140
+G GSFG + + N + AIK +K D Q++ ILS + +G
Sbjct: 207 LGTGSFGRVHLVQSNHNRLYYAIKVLEKKKIVDMKQIEHTCDERYILSRVQHPFITILWG 266
Query: 141 --QEGLHNILVIDLL-GPSLEDLFDWCGRRFSIKTVVHVAIQMITLIEELHDHDLIYRDI 197
Q+ + +V+D G L L C RF K A ++I ++ LH + ++YRD+
Sbjct: 267 TFQDAKNLFMVMDFAEGGELFSLLRKC-HRFPEKVAKFYAAEVILALDYLHHNQIVYRDL 325
Query: 198 KPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTARYMSINTHLG 257
KP+N L+ R + ++DFG AK + +L GT Y++
Sbjct: 326 KPENLLLDR-----FGHLKIVDFGFAK---------RVSTSNCCTLCGTPDYLAPEIISL 371
Query: 258 REQSRRDDMEALGHVFFYFLRGQLPWQGLKAANNKLK-YEKIGEKK 302
+ ++ D +LG + F L G P+ + N +K YE I E K
Sbjct: 372 KPYNKAADWWSLGILIFEMLAGYPPFY----SENPMKLYENILEGK 413
>Hs19923570 [T] KOG0603 Ribosomal protein S6 kinase
Length = 733
Score = 53.1 bits (126), Expect = 1e-06
Identities = 53/218 (24%), Positives = 93/218 (42%), Gaps = 24/218 (11%)
Query: 77 YKIGKKIGEGSFGVLF-------EGVNMINNVPVAIKFEPRKTDAPQLKDEYRTYKILSG 129
+++ K +G+GS+G +F + + V K + D + K E ++
Sbjct: 59 FELLKVLGQGSYGKVFLVRKVKGSDAGQLYAMKVLKKATLKVRDRVRSKMERDILAEVNH 118
Query: 130 SEGIPQAYYFGQEGLHNILVIDLLGPSLEDLFDWCGRR--FSIKTVVHVAIQMITLIEEL 187
+ Y F EG L++D L DLF + F+ + V ++ ++ L
Sbjct: 119 PFIVKLHYAFQTEG-KLYLILDFLRGG--DLFTRLSKEVMFTEEDVKFYLAELALALDHL 175
Query: 188 HDHDLIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTA 247
H +IYRD+KP+N L+ + + + DFG++K D + + S GT
Sbjct: 176 HSLGIIYRDLKPENILL-----DEEGHIKITDFGLSKEAIDHDKRAY-------SFCGTI 223
Query: 248 RYMSINTHLGREQSRRDDMEALGHVFFYFLRGQLPWQG 285
YM+ R ++ D + G + F L G LP+QG
Sbjct: 224 EYMAPEVVNRRGHTQSADWWSFGVLMFEMLTGSLPFQG 261
>CE28218 [D] KOG0588 Serine/threonine protein kinase
Length = 914
Score = 53.1 bits (126), Expect = 1e-06
Identities = 53/211 (25%), Positives = 90/211 (42%), Gaps = 17/211 (8%)
Query: 77 YKIGKKIGEGSFGVLFEGVNMINNVPVAIKF-EPRKTDAPQLKDEYRTYKILSGSEGIPQ 135
YK+ K +G+G G++ G + I VAIK K L+ R I+ E
Sbjct: 47 YKLEKTLGKGQTGLVKTGTHCITGRKVAIKIVNKEKLSESVLQKVEREIAIMKLIEHPHV 106
Query: 136 AYYFGQEGLHNILVIDLLGPSLEDLFDWCGR--RFSIKTVVHVAIQMITLIEELHDHDLI 193
+ + L + L S +LFD+ R R K Q+I+ ++ H H++
Sbjct: 107 LHLYDVYENKKYLYLLLEHVSGGELFDYLVRKGRLMSKEARKFFRQIISALDFCHAHNIC 166
Query: 194 YRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTARYMSIN 253
+RD+KP+N L+ + N + + DFGMA L + ++ G+ Y
Sbjct: 167 HRDLKPENLLL-----DERNNIKVADFGMASL--------QVEGSMLETSCGSPHYACPE 213
Query: 254 THLGRE-QSRRDDMEALGHVFFYFLRGQLPW 283
G + R+ D+ + G + + L G LP+
Sbjct: 214 VIRGEKYDGRKADVWSCGVILYALLVGALPF 244
>CE20258 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 353
Score = 53.1 bits (126), Expect = 1e-06
Identities = 57/210 (27%), Positives = 91/210 (43%), Gaps = 21/210 (10%)
Query: 82 KIGEGSFGVLFEGVNMINNVPVAIKFEPRKTDAPQLKD----EYRTYKILSGSEGIPQAY 137
K+GEGS+GV+++ N VAIK D P +K E R K L +
Sbjct: 9 KLGEGSYGVVYKCKNRDTGQIVAIKKFVETEDDPHIKKIALREIRMLKQLKHQNLVGLIE 68
Query: 138 YFGQEG-LHNILVIDLLGPSLEDLFDWCGRRFSIKTVVHVAIQMITLIEELHDHDLIYRD 196
F + LH LV +L ++ + + + + + Q++ ++ H H I+RD
Sbjct: 69 VFKRNRKLH--LVFELCDRTVLHELEKNPHGVNDELIKKIIYQLLEALKFCHSHKCIHRD 126
Query: 197 IKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTARYMSINTHL 256
+KP+N + R +Q V L DFG A++ T+ + Y T Y S +
Sbjct: 127 VKPENIFLTRNDQ-----VKLGDFGFARIIN--TTEMYTDY------VATRWYRSPELLV 173
Query: 257 GREQ-SRRDDMEALGHVFFYFLRGQLPWQG 285
G Q D+ A+G V+ L G+ W G
Sbjct: 174 GDVQYGPPVDIWAVGCVYAELLTGEALWPG 203
>Hs4502803 [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 476
Score = 52.8 bits (125), Expect = 1e-06
Identities = 62/240 (25%), Positives = 107/240 (43%), Gaps = 21/240 (8%)
Query: 83 IGEGSFGVLFEGVNMINNVPVAIKFEPRK--TDAPQ-LKDEYRTYKILSGSEGIPQAYYF 139
+GEG++G + VN + VA+K K D P+ +K E K+L+ E + + Y
Sbjct: 15 LGEGAYGEVQLAVNRVTEEAVAVKIVDMKRAVDCPENIKKEICINKMLN-HENVVKFYGH 73
Query: 140 GQEGLHNILVIDLLGPSLEDLFDWCGRRFSIKT--VVHVAIQMITLIEELHDHDLIYRDI 197
+EG NI + L S +LFD + Q++ + LH + +RDI
Sbjct: 74 RREG--NIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLMAGVVYLHGIGITHRDI 131
Query: 198 KPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTARYMSINTHLG 257
KP+N L+ + + + + DFG+A ++R + R + GT Y++
Sbjct: 132 KPENLLL-----DERDNLKISDFGLATVFRYNNRE-----RLLNKMCGTLPYVAPELLKR 181
Query: 258 RE-QSRRDDMEALGHVFFYFLRGQLPWQGLKAANNKLKYEKIGEKKRSTNVYDLSQGLPV 316
RE + D+ + G V L G+LPW + +++ +Y EKK N + P+
Sbjct: 182 REFHAEPVDVWSCGIVLTAMLAGELPWD--QPSDSCQEYSDWKEKKTYLNPWKKIDSAPL 239
>CE06635 [Z] KOG0613 Projectin/twitchin and related proteins
Length = 7160
Score = 52.8 bits (125), Expect = 1e-06
Identities = 48/212 (22%), Positives = 91/212 (42%), Gaps = 13/212 (6%)
Query: 76 HYKIGKKIGEGSFGVLFEGVNMINNVPVAIKF--EPRKTDAPQLKDEYRTYKILSGSEGI 133
HY I +++G G+FGV+ A KF P ++D ++ E +T +L +
Sbjct: 6262 HYDIHEELGTGAFGVVHRVTERATGNNFAAKFVMTPHESDKETVRKEIQTMSVLRHPTLV 6321
Query: 134 PQAYYFGQEGLHNILVIDLLGPSLEDLFDWCGRRFSIKTVVHVAIQMITLIEELHDHDLI 193
F + ++ + G L + + S V Q+ + +H+++ +
Sbjct: 6322 NLHDAFEDDNEMVMIYEFMSGGELFEKVADEHNKMSEDEAVEYMRQVCKGLCHMHENNYV 6381
Query: 194 YRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTARYMSIN 253
+ D+KP+N + +N + LIDFG+ + DPK + K +GTA + +
Sbjct: 6382 HLDLKPENIMF---TTKRSNELKLIDFGLT-AHLDPK-------QSVKVTTGTAEFAAPE 6430
Query: 254 THLGREQSRRDDMEALGHVFFYFLRGQLPWQG 285
G+ DM ++G + + L G P+ G
Sbjct: 6431 VAEGKPVGYYTDMWSVGVLSYILLSGLSPFGG 6462
>CE06634 [Z] KOG0613 Projectin/twitchin and related proteins
Length = 6831
Score = 52.8 bits (125), Expect = 1e-06
Identities = 48/212 (22%), Positives = 91/212 (42%), Gaps = 13/212 (6%)
Query: 76 HYKIGKKIGEGSFGVLFEGVNMINNVPVAIKF--EPRKTDAPQLKDEYRTYKILSGSEGI 133
HY I +++G G+FGV+ A KF P ++D ++ E +T +L +
Sbjct: 5933 HYDIHEELGTGAFGVVHRVTERATGNNFAAKFVMTPHESDKETVRKEIQTMSVLRHPTLV 5992
Query: 134 PQAYYFGQEGLHNILVIDLLGPSLEDLFDWCGRRFSIKTVVHVAIQMITLIEELHDHDLI 193
F + ++ + G L + + S V Q+ + +H+++ +
Sbjct: 5993 NLHDAFEDDNEMVMIYEFMSGGELFEKVADEHNKMSEDEAVEYMRQVCKGLCHMHENNYV 6052
Query: 194 YRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTARYMSIN 253
+ D+KP+N + +N + LIDFG+ + DPK + K +GTA + +
Sbjct: 6053 HLDLKPENIMF---TTKRSNELKLIDFGLT-AHLDPK-------QSVKVTTGTAEFAAPE 6101
Query: 254 THLGREQSRRDDMEALGHVFFYFLRGQLPWQG 285
G+ DM ++G + + L G P+ G
Sbjct: 6102 VAEGKPVGYYTDMWSVGVLSYILLSGLSPFGG 6133
>At2g17290 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 544
Score = 52.8 bits (125), Expect = 1e-06
Identities = 50/217 (23%), Positives = 99/217 (45%), Gaps = 26/217 (11%)
Query: 77 YKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPR-----KTDAPQLKDEYRTYKILSGSE 131
Y + +K+G+G FG + ++ V A K + K D ++ E + L+G +
Sbjct: 85 YTLSRKLGQGQFGTTYLCTDIATGVDYACKSISKRKLISKEDVEDVRREIQIMHHLAGHK 144
Query: 132 GIPQAYYFGQEGLHNILVIDLLGPSLEDLFDWCGRR--FSIKTVVHVAIQMITLIEELHD 189
I ++ L+ +V++L +LFD R +S + + ++ ++E H
Sbjct: 145 NIVTIKGAYEDPLYVHIVMELCAGG--ELFDRIIHRGHYSERKAAELTKIIVGVVEACHS 202
Query: 190 HDLIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTARY 249
+++RD+KP+NFL+ N+ D + IDFG++ ++ P + K + G+ Y
Sbjct: 203 LGVMHRDLKPENFLL--VNKDDDFSLKAIDFGLSVFFK--------PGQIFKDVVGSPYY 252
Query: 250 MS---INTHLGREQSRRDDMEALGHVFFYFLRGQLPW 283
++ + H G E D+ G + + L G P+
Sbjct: 253 VAPEVLLKHYGPEA----DVWTAGVILYILLSGVPPF 285
>YBR028c [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 525
Score = 52.4 bits (124), Expect = 2e-06
Identities = 41/147 (27%), Positives = 72/147 (48%), Gaps = 12/147 (8%)
Query: 172 TVVHVAIQMITLIEELHDHDLIYRDIKPDNFLIGRPNQPDANMVHLIDFGMA-KLYRDPK 230
TV A ++ + LH ++YRD+KP+N L+ + + L DFG++ K D
Sbjct: 253 TVSFYAAEISCALRFLHTKGVVYRDLKPENCLLNQRGH-----LVLTDFGLSKKSANDSA 307
Query: 231 TKQHIPYREKK--SLSGTARYMSINTHLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKA 288
+ P S+ GT Y + LG+ S+ D +LG + + L G+ P+ G
Sbjct: 308 VDEEDPENVNALYSIIGTPEYCAPEILLGKAYSQNCDWYSLGCLLYDMLVGKPPYTG--- 364
Query: 289 ANNKLKYEKIGEKKRSTNV-YDLSQGL 314
+N+K+ KI + K+ + + LS+G+
Sbjct: 365 SNHKVIINKIQQNKQGPKIPFYLSEGM 391
>CE28744 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 879
Score = 52.4 bits (124), Expect = 2e-06
Identities = 58/221 (26%), Positives = 91/221 (40%), Gaps = 36/221 (16%)
Query: 81 KKIGEGSFGVLFE---------GVNMINNVPVAIKFEPRKTDAPQLKDEYRTYKILSGSE 131
K +GEG +G +F+ G V K + D +DE + + ++ S
Sbjct: 27 KLVGEGGYGKVFQVRKQTGEDKGTIYAMKVITKRKVTGTEKDLRHARDERKILETIN-SP 85
Query: 132 GIPQAYYFGQEGLHNILVIDLLGPS-----LEDLFDWCGR--RFSIKTVVHVAIQMITLI 184
+ +Y Q LV++ L LE DW RF + ++I I
Sbjct: 86 FLCDLHYAFQTNEKLYLVLEFLHGGELYTLLERKSDWPEEYARFYLS-------EIILAI 138
Query: 185 EELHDHDLIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLS 244
E LH HD++YRD+KPDN ++ A V L DFG+ K Y+ K ++ + +
Sbjct: 139 EHLHGHDIVYRDLKPDNVMLNL-----AGHVVLTDFGLCK-YKLKKGEKTLTF------C 186
Query: 245 GTARYMSINTHLGREQSRRDDMEALGHVFFYFLRGQLPWQG 285
GT YM+ D+ ALG + + G P+ G
Sbjct: 187 GTHEYMAPEMIRKVGHDHAVDVWALGILMYDMFMGGPPFTG 227
>CE28571 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 706
Score = 52.4 bits (124), Expect = 2e-06
Identities = 54/203 (26%), Positives = 96/203 (46%), Gaps = 13/203 (6%)
Query: 81 KKIGEGSFGVLFEGVNMINNVPVAIKFEPRKTDAPQLKDEYRTYKILSGSEGIPQAYYFG 140
K+IG+G FGV++ N VAIK +K ++ E +T K L S+ + + Y
Sbjct: 17 KEIGKGGFGVVY-AAQRENGEKVAIKRIDKKVPKNRVWTEIQTMKELKKSKYVVEFYEDF 75
Query: 141 QEGLHNILVIDLL-GPSLEDLFDWCGRRFSIKTVVHVAIQMITLIEELHDHDLIYRDIKP 199
E + +V++L G SL+ G T VHV Q+I+ + +H ++I+RD+
Sbjct: 76 VEDGYTYIVMELCEGGSLQAYVREHGA-LDDATAVHVLRQLISAVSFMHRVNVIHRDLSA 134
Query: 200 DNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTARYMSINTHLGRE 259
N I + ++ V L DFG+A +T ++ GT +++ + +E
Sbjct: 135 GNVFI-KDSKKKKMTVKLGDFGLATTLGRGET--------TCTIVGTPGFIAPQVY-DQE 184
Query: 260 QSRRDDMEALGHVFFYFLRGQLP 282
++ D+ +LG V + L + P
Sbjct: 185 YTQSADVYSLGAVLYTMLTARNP 207
>CE27220 [T] KOG0660 Mitogen-activated protein kinase
Length = 472
Score = 52.4 bits (124), Expect = 2e-06
Identities = 45/165 (27%), Positives = 74/165 (44%), Gaps = 13/165 (7%)
Query: 77 YKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPRKTDAPQLK----DEYRTYKILSGSEG 132
Y+ + IG G+FG++ E V +N VAIK + P L E R + ++
Sbjct: 82 YEPTQNIGSGAFGIVCEAVETSSNQKVAIKKVAHASATPTLARRTLREIRVLRYINHPNI 141
Query: 133 IPQAYYF---GQEGLHNILVIDLLGPSLEDLFDWCGRRFSIKTVVHVAIQMITLIEELHD 189
+P F G G+ LV+DL+ +L + + Q++ +E LH
Sbjct: 142 VPLRDIFRTKGPLGIDVFLVMDLMQNNLHHIIYGNEDPLEEHYINAFLGQLLRGLEYLHA 201
Query: 190 HDLIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQH 234
+ +RD+KP N L+ + + + DFGMAK D +K+H
Sbjct: 202 ACIAHRDLKPSNLLVNQD-----GTLRIADFGMAKC-ADNSSKKH 240
>CE26649 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 648
Score = 52.4 bits (124), Expect = 2e-06
Identities = 51/217 (23%), Positives = 96/217 (43%), Gaps = 21/217 (9%)
Query: 74 GLHYKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPRKTDAPQLKDEYRTYKILSGSE-- 131
G +Y+ G+ +G+G F +E N VA K P+ Q + + T ++ E
Sbjct: 35 GTYYEKGRFLGKGGFAHCYELTNRATREVVAGKVVPKSMLVKQYQRDKMTQEVQIHRELG 94
Query: 132 --GIPQAYYFGQEGLHNILVIDLLGPSLEDLFDWCGRRFSIKT--VVHVAIQMITLIEEL 187
I + + F ++ L+ + ++L + L + RR ++ + Q++ + L
Sbjct: 95 HINIVKLFNFFEDNLNVYITLELC--ARRSLMELHKRRKAVTEPEARYFTHQIVDGVLYL 152
Query: 188 HDHDLIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTA 247
HD ++I+RD+K N + D +V + DFG+A + KK+L GT
Sbjct: 153 HDLNIIHRDMKLGNLFLN-----DDLVVKIGDFGLATTVNGDE--------RKKTLCGTP 199
Query: 248 RYMSINTHLGREQSRRDDMEALGHVFFYFLRGQLPWQ 284
Y++ S D+ A+G + + L GQ P++
Sbjct: 200 NYIAPEVLNKAGHSFEVDIWAVGCILYILLFGQPPFE 236
>At3g57530 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 560
Score = 52.4 bits (124), Expect = 2e-06
Identities = 59/250 (23%), Positives = 109/250 (43%), Gaps = 31/250 (12%)
Query: 77 YKIGKKIGEGSFGVLFEGVNMINNVPVAIK--FEPRKTDAPQLKDEYRTYKILSGSEGIP 134
Y +G+++G G FGV + + + A K + + A ++D R +I+ P
Sbjct: 63 YTLGRELGRGEFGVTYLCTDKETDDVFACKSILKKKLRTAVDIEDVRREVEIMRHMPEHP 122
Query: 135 QAY-----YFGQEGLHNILVIDLLGPSLEDLFDWCGRR--FSIKTVVHVAIQMITLIEEL 187
Y + +H LV++L +LFD R ++ + V ++ +++
Sbjct: 123 NVVTLKETYEDEHAVH--LVMELCEGG--ELFDRIVARGHYTERAAAAVTKTIMEVVQVC 178
Query: 188 HDHDLIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTA 247
H H +++RD+KP+NFL G N+ + + IDFG++ ++ P + G+
Sbjct: 179 HKHGVMHRDLKPENFLFG--NKKETAPLKAIDFGLSVFFK--------PGERFNEIVGSP 228
Query: 248 RYMSINTHLGREQSRRDDMEALGHVFFYFLRGQLPW-----QGLKAA--NNKLKYEKIGE 300
YM+ L R D+ + G + + L G P+ QG+ A + L + +
Sbjct: 229 YYMAPEV-LKRNYGPEVDIWSAGVILYILLCGVPPFWAETEQGVAQAIIRSVLDFRRDPW 287
Query: 301 KKRSTNVYDL 310
K S N DL
Sbjct: 288 PKVSENAKDL 297
>At3g06620 [T] KOG0192 Tyrosine kinase specific for activated (GTP-bound)
p21cdc42Hs
Length = 773
Score = 52.4 bits (124), Expect = 2e-06
Identities = 55/223 (24%), Positives = 94/223 (41%), Gaps = 34/223 (15%)
Query: 79 IGKKIGEGSFGVLFEGVNMINNVPVAI--KFEPRKTDAPQLKDEYRTYK--------ILS 128
IG+++G+GS G ++ G+ ++V V + K E K E K +
Sbjct: 496 IGEQVGQGSCGTVYHGLWFGSDVAVKVFSKQEYSAEVIESFKQEVLLMKRLRHPNVLLFM 555
Query: 129 GSEGIPQAYYFGQEGLHNILVIDLLGPSLEDLFDWCGRRFSIKTVVHVAIQMITLIEELH 188
G+ PQ E L + LL S L DW R +H+A+ + + LH
Sbjct: 556 GAVTSPQRLCIVSEFLPRGSLFRLLQKSTSKL-DWRRR-------IHMALDIARGMNYLH 607
Query: 189 --DHDLIYRDIKPDNFLIGRPNQPDANM-VHLIDFGMAKLYRDPKTKQHIPYREKKSLSG 245
+I+RD+K N L+ D N V + DFG++++ +H Y KS G
Sbjct: 608 HCSPPIIHRDLKSSNLLV------DKNWTVKVADFGLSRI-------KHETYLTSKSGKG 654
Query: 246 TARYMSINTHLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKA 288
T ++M+ + D+ + G V + ++PW+ L +
Sbjct: 655 TPQWMAPEVLRNESADEKSDIYSFGVVLWELATEKIPWETLNS 697
>7302199 [T] KOG0197 Tyrosine kinases
Length = 517
Score = 52.4 bits (124), Expect = 2e-06
Identities = 49/165 (29%), Positives = 81/165 (48%), Gaps = 10/165 (6%)
Query: 78 KIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPRKT-DAPQLKDEYRTYKILSGSEGIP-Q 135
K +K+G G FG ++EG+ N PVAIK T D E + K L ++ I
Sbjct: 249 KFVRKLGSGQFGDVWEGL-WNNTTPVAIKTLKSGTMDPKDFLAEAQIMKKLRHTKLIQLY 307
Query: 136 AYYFGQEGLHNILVIDLLGPSLEDLFDWCGRRFSIK--TVVHVAIQMITLIEELHDHDLI 193
A +E ++ I + G LE L G+ S+K T++ +A Q+ + L + I
Sbjct: 308 AVCTVEEPIYIITELMKHGSLLEYLQAIAGKGRSLKMQTLIDMAAQIAAGMAYLESQNYI 367
Query: 194 YRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYR 238
+RD+ N L+G D N+V + DFG+A+L ++ + + + R
Sbjct: 368 HRDLAARNVLVG-----DGNIVKIADFGLARLIKEDEYEARVGAR 407
>YPL203w [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 380
Score = 52.0 bits (123), Expect = 2e-06
Identities = 60/232 (25%), Positives = 100/232 (42%), Gaps = 26/232 (11%)
Query: 77 YKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPRKT-----DAPQLKDEYRTYKILSGSE 131
++I + +G GSFG + ++ N AIK ++ DE R K++
Sbjct: 70 FQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKQQVVKMKQVEHTNDERRMLKLVEHPF 129
Query: 132 GIPQAYYFGQEGLHNILVIDLL-GPSLEDLFDWCGRRFSIKTVVHVAIQMITLIEELHDH 190
I F Q+ + +V+D + G L L +RF A ++I +E LH H
Sbjct: 130 LIRMWGTF-QDARNIFMVMDYIEGGELFSLLRK-SQRFPNPVAKFYAAEVILALEYLHAH 187
Query: 191 DLIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTARYM 250
++IYRD+KP+N L+ R + + DFG A K Q + + +L GT Y+
Sbjct: 188 NIIYRDLKPENILLDRNGH-----IKITDFGFA------KEVQTVTW----TLCGTPDYI 232
Query: 251 SINTHLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKAANNKLKYEKIGEKK 302
+ + ++ D +LG + + L G P+ YEKI + K
Sbjct: 233 APEVITTKPYNKSVDWWSLGVLIYEMLAGYTPFYDTTPMKT---YEKILQGK 281
>YFR014c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 446
Score = 52.0 bits (123), Expect = 2e-06
Identities = 43/177 (24%), Positives = 82/177 (46%), Gaps = 12/177 (6%)
Query: 77 YKIGKKIGEGSFGVLFEGVNMINNVPVAIKF------EPRKTDAPQLKDEYRTYKILSGS 130
Y GK +G G+FGV+ + N VA+K + K L DE + L
Sbjct: 37 YVFGKTLGAGTFGVVRQAKNTETGEDVAVKILIKKALKGNKVQLEALYDELDILQRLHHP 96
Query: 131 EGIPQAYYFGQEGLHNILVIDLLGPSLEDLFDWCGRRFSIKTVVHVAIQMITLIEELHDH 190
+ +F + I+ G L D G+ F+ + V + +++++ ++ +H
Sbjct: 97 NIVAFKDWFESKDKFYIITQLAKGGELFDRILKKGK-FTEEDAVRILVEILSAVKYMHSQ 155
Query: 191 DLIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTA 247
++++RD+KP+N L ++ D + + + DFG+AK K+ + + Y+ SL A
Sbjct: 156 NIVHRDLKPENLLY--IDKSDESPLVVADFGIAKRL---KSDEELLYKPAGSLGYVA 207
>Hs20545245 [D] KOG0588 Serine/threonine protein kinase
Length = 795
Score = 52.0 bits (123), Expect = 2e-06
Identities = 55/211 (26%), Positives = 89/211 (42%), Gaps = 17/211 (8%)
Query: 77 YKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPR-KTDAPQLKDEYRTYKILSGSEGIPQ 135
Y++ K +G+G G++ GV+ I VAIK R K L R IL E
Sbjct: 51 YRLEKTLGKGQTGLVKLGVHCITGQKVAIKIVNREKLSESVLMKVEREIAILKLIEHPHV 110
Query: 136 AYYFGQEGLHNILVIDLLGPSLEDLFDWCGR--RFSIKTVVHVAIQMITLIEELHDHDLI 193
L + L S +LFD+ + R + K Q+++ ++ H + +
Sbjct: 111 LKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIVSALDFCHSYSIC 170
Query: 194 YRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTARYMSIN 253
+RD+KP+N L+ + N + + DFGMA L + ++ G+ Y
Sbjct: 171 HRDLKPENLLL-----DEKNNIRIADFGMASL--------QVGDSLLETSCGSPHYACPE 217
Query: 254 THLGRE-QSRRDDMEALGHVFFYFLRGQLPW 283
G + RR DM + G + F L G LP+
Sbjct: 218 VIKGEKYDGRRADMWSCGVILFALLVGALPF 248
>Hs19923468 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD and related
proteins
Length = 878
Score = 52.0 bits (123), Expect = 2e-06
Identities = 48/217 (22%), Positives = 96/217 (44%), Gaps = 16/217 (7%)
Query: 83 IGEGSFGVLFEGVNMINNVPVAIKFE-----PRKTDAPQLKDEYRTYKILSGSEGIPQAY 137
+G G FGV++ G + VA+K P K ++ QL++E + L +
Sbjct: 557 LGSGQFGVVYGGKHRKTGRDVAVKVIDKLRFPTKQES-QLRNEVAILQSLRHPGIVNLEC 615
Query: 138 YFGQEGLHNILVIDLLGPSLEDLFDWCGRRFSIKTVVHVAIQMITLIEELHDHDLIYRDI 197
F +++ L G LE + R + + Q++ + LH ++++ D+
Sbjct: 616 MFETPEKVFVVMEKLHGDMLEMILSSEKGRLPERLTKFLITQILVALRHLHFKNIVHCDL 675
Query: 198 KPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTARYMSINTHLG 257
KP+N L+ + V L DFG A++ + ++S+ GT Y++ L
Sbjct: 676 KPENVLLA--SADPFPQVKLCDFGFARIIGEKSF--------RRSVVGTPAYLAPEVLLN 725
Query: 258 REQSRRDDMEALGHVFFYFLRGQLPWQGLKAANNKLK 294
+ +R DM ++G + + L G P+ + N++++
Sbjct: 726 QGYNRSLDMWSVGVIMYVSLSGTFPFNEDEDINDQIQ 762
>ECU10g0120 [L] KOG1167 Serine/threonine protein kinase of the CDC7 subfamily
involved in DNA synthesis repair and recombination
Length = 351
Score = 52.0 bits (123), Expect = 2e-06
Identities = 42/154 (27%), Positives = 71/154 (45%), Gaps = 8/154 (5%)
Query: 81 KKIGEGSFGVLFEGVNMINNVPVAIKFEPRKTDAPQLKDEYRTYKILSGSEGIPQAYYFG 140
+KIGEGSF V+++ ++ + VA+K R + ++ DE K L G +
Sbjct: 25 EKIGEGSFSVVYKALDAESGRYVALKAITRTSSPARVLDEMMFLKTLGGRKNCMGLLGCF 84
Query: 141 QEGLHNILVIDLLGPSLEDLFDWCGRRFSIKTVVHVAIQMITLIEELHDHDLIYRDIKPD 200
+ + V P F IK +H ++ IE +H + +++RD+KP
Sbjct: 85 RNEDQVVAVFPYFEPIDFREFISNANLADIKRYLH---NLLIAIEHVHSNGIMHRDLKPG 141
Query: 201 NFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQH 234
NFL + ++ LIDFG+A+ Y + QH
Sbjct: 142 NFLYNK----ESGRGMLIDFGLAQ-YEEYSEGQH 170
>ECU08g1960 [L] KOG1167 Serine/threonine protein kinase of the CDC7 subfamily
involved in DNA synthesis repair and recombination
Length = 351
Score = 52.0 bits (123), Expect = 2e-06
Identities = 42/154 (27%), Positives = 71/154 (45%), Gaps = 8/154 (5%)
Query: 81 KKIGEGSFGVLFEGVNMINNVPVAIKFEPRKTDAPQLKDEYRTYKILSGSEGIPQAYYFG 140
+KIGEGSF V+++ ++ + VA+K R + ++ DE K L G +
Sbjct: 25 EKIGEGSFSVVYKALDAESGRYVALKAITRTSSPARVLDEMMFLKTLGGRKNCMGLLGCF 84
Query: 141 QEGLHNILVIDLLGPSLEDLFDWCGRRFSIKTVVHVAIQMITLIEELHDHDLIYRDIKPD 200
+ + V P F IK +H ++ IE +H + +++RD+KP
Sbjct: 85 RNEDQVVAVFPYFEPIDFREFISNANLADIKRYLH---NLLIAIEHVHSNGIMHRDLKPG 141
Query: 201 NFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQH 234
NFL + ++ LIDFG+A+ Y + QH
Sbjct: 142 NFLYNK----ESGRGMLIDFGLAQ-YEEYSEGQH 170
>CE06762 [T] KOG0660 Mitogen-activated protein kinase
Length = 367
Score = 52.0 bits (123), Expect = 2e-06
Identities = 45/165 (27%), Positives = 72/165 (43%), Gaps = 13/165 (7%)
Query: 74 GLHYKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPRKTDAPQLKD----EYRTYKILSG 129
G Y + +G G++GV+ + ++ N VAIK PR A L E R + L
Sbjct: 54 GTPYLAEENVGAGAYGVVCKAMDTRNKKQVAIKKIPRAFTAHTLAKRSLREVRILRELLH 113
Query: 130 SEGIPQAYYFGQEGLHN---ILVIDLLGPSLEDLFDWCGRRFSIKTVVHVAIQMITLIEE 186
I F EG H LV+DL+ L + + + + Q++ ++
Sbjct: 114 ENIIAVLDMFTAEGAHGKDIYLVMDLMETDLHQILH-SRQTLMEQHFQYFFYQLLRGLKY 172
Query: 187 LHDHDLIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKT 231
LH +I+RD+KP N L+ ++ + DFGMA+ Y T
Sbjct: 173 LHSAGIIHRDLKPSNLLLN-----GDCLLRIADFGMARAYASAST 212
>CE04173 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 531
Score = 52.0 bits (123), Expect = 2e-06
Identities = 46/178 (25%), Positives = 85/178 (46%), Gaps = 20/178 (11%)
Query: 73 VGLHYKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPRKTDAPQLKDEYRTYKILSGSEG 132
+G Y I K IG+G +GV+ E + VAI+ + AP++ YR +++
Sbjct: 191 IGYRYTIDKVIGQGCYGVVGEATDGKTKQKVAIRMVSKL--APRI---YRETEMIMYISS 245
Query: 133 IPQAYYFGQEGLHNILVIDLLGPSLEDLFDWCGRRF---------SIKTVVHVAIQMITL 183
I + F + + V + DLFD +++ +++ V + +++
Sbjct: 246 IDPDHTFDCVRMLDYNVFRGFHYVVTDLFDTSVKKYIKEHHPNGIALENVAAMGRKILKG 305
Query: 184 IEELHDHDLIYRDIKPDNFLIGRPNQPDANMVHLIDFGM---AKLYRDPKTKQHIPYR 238
+ LH+H++++ D+KP+N ++ N + N V L DFG+ AK Y D Q + YR
Sbjct: 306 LVFLHEHNIVHGDLKPENIML---NLANPNDVKLGDFGLSRFAKPYHDHVQCQSMFYR 360
>CE02377 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 1211
Score = 52.0 bits (123), Expect = 2e-06
Identities = 52/229 (22%), Positives = 98/229 (42%), Gaps = 24/229 (10%)
Query: 77 YKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPRKTDAPQLKDEYRTYKILSGSEG---- 132
Y++ K +G+G FG ++ + A KF + +A + + E R IL+
Sbjct: 45 YQVTKLLGDGKFGKVYCVIEKETGKEFAAKFIKIRKEADRAEVE-REVSILTQLRHPRIA 103
Query: 133 -IPQAYYFGQEGLHNILVIDLLGPSLEDLFDWCGRR---FSIKTVVHVAIQMITLIEELH 188
I A+Y + +L+++++ +LFD S VV + Q+ I+ +H
Sbjct: 104 QIYDAFYTTTNDV--VLIMEIVRGG--ELFDRVAEESYVLSELAVVMIICQLCEAIDYIH 159
Query: 189 DHDLIYRDIKPDNFLIGRPNQPDANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTAR 248
++++ D+KP+N + N + LIDFG+A+ Y +E K ++GT
Sbjct: 160 KQNILHLDVKPENIMC---VSLTGNRIKLIDFGLARHYDGT--------QELKYMAGTPE 208
Query: 249 YMSINTHLGREQSRRDDMEALGHVFFYFLRGQLPWQGLKAANNKLKYEK 297
+ + + DM ++G + + L G P+ G EK
Sbjct: 209 FAAPEVIKFEKLDYHTDMWSIGVITYILLSGYSPFLGDNLGETYCNVEK 257
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.317 0.138 0.414
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,933,484
Number of Sequences: 60738
Number of extensions: 1257298
Number of successful extensions: 5441
Number of sequences better than 1.0e-05: 294
Number of HSP's better than 0.0 without gapping: 69
Number of HSP's successfully gapped in prelim test: 225
Number of HSP's that attempted gapping in prelim test: 4882
Number of HSP's gapped (non-prelim): 334
length of query: 536
length of database: 30,389,216
effective HSP length: 111
effective length of query: 425
effective length of database: 23,647,298
effective search space: 10050101650
effective search space used: 10050101650
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)