ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIV2806 good C KOG1335 Energy production and conversion Dihydrolipoamide dehydrogenase
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIV2806 952049 953527 493
(493 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YFL018c [C] KOG1335 Dihydrolipoamide dehydrogenase 775 0.0
SPAC1002.09c [C] KOG1335 Dihydrolipoamide dehydrogenase 595 e-170
7293932 [C] KOG1335 Dihydrolipoamide dehydrogenase 533 e-151
Hs4557525 [C] KOG1335 Dihydrolipoamide dehydrogenase 522 e-148
At3g17240 [C] KOG1335 Dihydrolipoamide dehydrogenase 518 e-147
At1g48030 [C] KOG1335 Dihydrolipoamide dehydrogenase 518 e-147
CE16262 [C] KOG1335 Dihydrolipoamide dehydrogenase 481 e-136
YPL017c [C] KOG1335 Dihydrolipoamide dehydrogenase 290 3e-78
At3g16950 [C] KOG1335 Dihydrolipoamide dehydrogenase 224 3e-58
SPBC17A3.07 [Q] KOG0405 Pyridine nucleotide-disulphide oxidoredu... 171 3e-42
YPL091w [Q] KOG0405 Pyridine nucleotide-disulphide oxidoreductase 167 3e-41
Hs10835189 [Q] KOG0405 Pyridine nucleotide-disulphide oxidoreduc... 166 1e-40
CE17558 [Q] KOG0405 Pyridine nucleotide-disulphide oxidoreductase 162 1e-39
At3g24170 [Q] KOG0405 Pyridine nucleotide-disulphide oxidoreductase 152 1e-36
Hs22035672 [O] KOG4716 Thioredoxin reductase 145 2e-34
Hs22035670 [O] KOG4716 Thioredoxin reductase 145 2e-34
HsM5454136 [O] KOG4716 Thioredoxin reductase 144 4e-34
At3g54660 [Q] KOG0405 Pyridine nucleotide-disulphide oxidoreductase 138 2e-32
Hs4507747 [O] KOG4716 Thioredoxin reductase 133 5e-31
CE26906 [O] KOG4716 Thioredoxin reductase 132 1e-30
Hs20536269 [O] KOG4716 Thioredoxin reductase 126 8e-29
7290913 [O] KOG4716 Thioredoxin reductase 125 2e-28
7296552 [O] KOG4716 Thioredoxin reductase 114 3e-25
CE15373 [O] KOG4716 Thioredoxin reductase 113 6e-25
Hs22035668 [O] KOG4716 Thioredoxin reductase 96 1e-19
CE27373 [R] KOG1336 Monodehydroascorbate/ferredoxin reductase 61 4e-09
YMR145c [C] KOG2495 NADH-dehydrogenase (ubiquinone) 50 8e-06
>YFL018c [C] KOG1335 Dihydrolipoamide dehydrogenase
Length = 499
Score = 775 bits (2002), Expect = 0.0
Identities = 384/490 (78%), Positives = 433/490 (88%), Gaps = 2/490 (0%)
Query: 5 NSTRSFSSSALLKTVTKKHDLVVIGGGPGGYVAAIKAAQLGYDVACVEKRGRLGGTCLNV 64
N+ R+FSS+ T+ K HD+V+IGGGP GYVAAIKAAQLG++ ACVEKRG+LGGTCLNV
Sbjct: 9 NNKRAFSSTVRTLTINKSHDVVIIGGGPAGYVAAIKAAQLGFNTACVEKRGKLGGTCLNV 68
Query: 65 GCIPSKALLNNSHLYHQMKTDAKQRGIDINGEININVAQFQKAKDTVVKQLTGGIEMLFK 124
GCIPSKALLNNSHL+HQM T+A++RGID+NG+I INVA FQKAKD VKQLTGGIE+LFK
Sbjct: 69 GCIPSKALLNNSHLFHQMHTEAQKRGIDVNGDIKINVANFQKAKDDAVKQLTGGIELLFK 128
Query: 125 KNGVTYYKGLGAFETDKSVKVLPVEGLEGSVTEDHLLESDRIIVATGSEVTPFPGITIDE 184
KN VTYYKG G+FE + ++V PV+GLEG+V EDH+L+ IIVATGSEVTPFPGI IDE
Sbjct: 129 KNKVTYYKGNGSFEDETKIRVTPVDGLEGTVKEDHILDVKNIIVATGSEVTPFPGIEIDE 188
Query: 185 ERIVSSTGALSLKEIPKKLAXXXXXXXXLEMGSVYSRLGSKVTVIEFQPQIGATMDGEVA 244
E+IVSSTGALSLKEIPK+L LEMGSVYSRLGSKVTV+EFQPQIGA+MDGEVA
Sbjct: 189 EKIVSSTGALSLKEIPKRLTIIGGGIIGLEMGSVYSRLGSKVTVVEFQPQIGASMDGEVA 248
Query: 245 QTTQKILKKQGLDFKLSTKVLSASRNGD--VVDIEVEGAKNGKKESLQADVLLVAVGRRP 302
+ TQK LKKQGLDFKLSTKV+SA RN D VV+I VE K K+E+L+A+VLLVAVGRRP
Sbjct: 249 KATQKFLKKQGLDFKLSTKVISAKRNDDKNVVEIVVEDTKTNKQENLEAEVLLVAVGRRP 308
Query: 303 YVAGLNAEKIGLEVDKRGRLVIDEQLSTKFPHVKVIGDVTFGPMLAHKAEEEGIAAAEYF 362
Y+AGL AEKIGLEVDKRGRLVID+Q ++KFPH+KV+GDVTFGPMLAHKAEEEGIAA E
Sbjct: 309 YIAGLGAEKIGLEVDKRGRLVIDDQFNSKFPHIKVVGDVTFGPMLAHKAEEEGIAAVEML 368
Query: 363 KVGHGHVNYGNIPAVMYSHPEVAWVGKTEEQLKEAGIQYKIGKFPFIANSRAKTNMDTEG 422
K GHGHVNY NIP+VMYSHPEVAWVGKTEEQLKEAGI YKIGKFPF ANSRAKTN DTEG
Sbjct: 369 KTGHGHVNYNNIPSVMYSHPEVAWVGKTEEQLKEAGIDYKIGKFPFAANSRAKTNQDTEG 428
Query: 423 FVKILIDAESERLLGAHIIGPNAGEMIAEAGLALEYGASAEDIARVCHAHPTLSEAFKEA 482
FVKILID+++ER+LGAHIIGPNAGEMIAEAGLALEYGASAED+ARVCHAHPTLSEAFKEA
Sbjct: 429 FVKILIDSKTERILGAHIIGPNAGEMIAEAGLALEYGASAEDVARVCHAHPTLSEAFKEA 488
Query: 483 NLAAYAKPIN 492
N+AAY K I+
Sbjct: 489 NMAAYDKAIH 498
>SPAC1002.09c [C] KOG1335 Dihydrolipoamide dehydrogenase
Length = 511
Score = 595 bits (1535), Expect = e-170
Identities = 292/473 (61%), Positives = 369/473 (77%), Gaps = 7/473 (1%)
Query: 22 KHDLVVIGGGPGGYVAAIKAAQLGYDVACVEKRGRLGGTCLNVGCIPSKALLNNSHLYHQ 81
++DL VIGGGPGGYVAAI+ AQLG CVEKRG LGGTCLNVGCIPSKALLNNSH+YH
Sbjct: 45 EYDLCVIGGGPGGYVAAIRGAQLGLKTICVEKRGTLGGTCLNVGCIPSKALLNNSHIYHT 104
Query: 82 MKTDAKQRGIDINGEININVAQFQKAKDTVVKQLTGGIEMLFKKNGVTYYKGLGAFETDK 141
+K D K+RGID++G +++N++Q KAKD VK LT GIE LFKKN V Y KG G+F +
Sbjct: 105 VKHDTKRRGIDVSG-VSVNLSQMMKAKDDSVKSLTSGIEYLFKKNKVEYAKGTGSFIDPQ 163
Query: 142 SVKVLPVEGLEGSVTEDHLLESDRIIVATGSEVTPFPGITIDEERIVSSTGALSLKEIPK 201
+ L V+G++G+ D +++ I+ATGSEV PFPG+TIDE++IVSSTGALSL E+PK
Sbjct: 164 T---LSVKGIDGAA--DQTIKAKNFIIATGSEVKPFPGVTIDEKKIVSSTGALSLSEVPK 218
Query: 202 KLAXXXXXXXXLEMGSVYSRLGSKVTVIEFQPQIGATMDGEVAQTTQKILKKQGLDFKLS 261
K+ LEMGSV+SRLG++VTV+EF P +G MD ++++ +I+ KQG+ FK S
Sbjct: 219 KMTVLGGGIIGLEMGSVWSRLGAEVTVVEFLPAVGGPMDADISKALSRIISKQGIKFKTS 278
Query: 262 TKVLSASRNGDVVDIEVEGAKNGKKESLQADVLLVAVGRRPYVAGLNAEKIGLEVDKRGR 321
TK+LSA NGD V++E+E KN K+E+ Q DVLLVA+GR PY GL +K+G+ +DK R
Sbjct: 279 TKLLSAKVNGDSVEVEIENMKNNKRETYQTDVLLVAIGRVPYTEGLGLDKLGISMDKSNR 338
Query: 322 LVIDEQLSTKFPHVKVIGDVTFGPMLAHKAEEEGIAAAEYFKVGHGHVNYGNIPAVMYSH 381
+++D + T PH++VIGD T GPMLAHKAE+EGIAA EY G GHVNY IPAVMY+H
Sbjct: 339 VIMDSEYRTNIPHIRVIGDATLGPMLAHKAEDEGIAAVEYIAKGQGHVNYNCIPAVMYTH 398
Query: 382 PEVAWVGKTEEQLKEAGIQYKIGKFPFIANSRAKTNMDTEGFVKILIDAESERLLGAHII 441
PEVAWVG TE++ KE+GI+Y+IG FPF ANSRAKTNMD +G VK+++DAE++RLLG H+I
Sbjct: 399 PEVAWVGITEQKAKESGIKYRIGTFPFSANSRAKTNMDADGLVKVIVDAETDRLLGVHMI 458
Query: 442 GPNAGEMIAEAGLALEYGASAEDIARVCHAHPTLSEAFKEANLAAY-AKPINF 493
GP AGE+I EA LALEYGASAED+ARVCHAHPTLSEA KEA +AA+ K I+F
Sbjct: 459 GPMAGELIGEATLALEYGASAEDVARVCHAHPTLSEATKEAMMAAWCGKSIHF 511
>7293932 [C] KOG1335 Dihydrolipoamide dehydrogenase
Length = 504
Score = 533 bits (1372), Expect = e-151
Identities = 277/495 (55%), Positives = 350/495 (69%), Gaps = 10/495 (2%)
Query: 2 LRFNSTRSFSSSALLKTVTKKHDLVVIGGGPGGYVAAIKAAQLGYDVACVEKRGRLGGTC 61
LR N+ + +A + T + D+VVIG GPGGYVAAIKAAQ+G VEK LGGTC
Sbjct: 17 LRTNAAILGALNARCYSSTHEADIVVIGSGPGGYVAAIKAAQMGMKTVSVEKEATLGGTC 76
Query: 62 LNVGCIPSKALLNNSHLYHQMKT-DAKQRGIDINGEININVAQFQKAKDTVVKQLTGGIE 120
LNVGCIPSKALLNNSH YH + D ++RGI G +++++ + K VK LTGGI
Sbjct: 77 LNVGCIPSKALLNNSHYYHMAHSGDLEKRGISC-GSVSLDLEKLMGQKSNAVKALTGGIA 135
Query: 121 MLFKKNGVTYYKGLGAFETDKSVKVLPVEGLEGSVTEDHLLESDRIIVATGSEVTPFPGI 180
MLFKKN VT G G V+V +G +V ++ I++ATGSEVTPFPGI
Sbjct: 136 MLFKKNKVTQLTGFGTIVNPNEVEVKKSDGSTETV------KTKNILIATGSEVTPFPGI 189
Query: 181 TIDEERIVSSTGALSLKEIPKKLAXXXXXXXXLEMGSVYSRLGSKVTVIEFQPQIGAT-M 239
IDEE IVSSTGAL L ++PK L LE+GSV+SRLG++VT IEF IG +
Sbjct: 190 EIDEEVIVSSTGALKLAKVPKHLVVIGAGVIGLELGSVWSRLGAEVTAIEFMDTIGGVGI 249
Query: 240 DGEVAQTTQKILKKQGLDFKLSTKVLSASRNGDVVDIEVEGAKNGKKESLQADVLLVAVG 299
D EV++T QK+L KQGL FKL TKV +ASR+GD V + VE AK+G+KE +Q D LLV+VG
Sbjct: 250 DNEVSKTFQKVLTKQGLKFKLGTKVTAASRSGDNVTVSVENAKSGEKEEIQCDALLVSVG 309
Query: 300 RRPYVAGLNAEKIGLEVDKRGRLVIDEQLSTKFPHVKVIGDVTFGPMLAHKAEEEGIAAA 359
RRPY GL E +G+ D RGR+ ++ T P++ IGD GPMLAHKAE+EG+
Sbjct: 310 RRPYTEGLGLEAVGIVKDDRGRIPVNATFQTVVPNIYAIGDCIHGPMLAHKAEDEGLITI 369
Query: 360 EYFKVGHGHVNYGNIPAVMYSHPEVAWVGKTEEQLKEAGIQYKIGKFPFIANSRAKTNMD 419
E GH H++Y +P+V+Y+HPEVAWVGK+EEQLK+ G+ YK+GKFPF+ANSRAKTN D
Sbjct: 370 EGINGGHVHIDYNCVPSVVYTHPEVAWVGKSEEQLKQEGVAYKVGKFPFLANSRAKTNND 429
Query: 420 TEGFVKILIDAESERLLGAHIIGPNAGEMIAEAGLALEYGASAEDIARVCHAHPTLSEAF 479
T+GFVK+L D ++++LG HIIGP AGE+I EA LA+EYGA+AED+ARVCHAHPT SEA
Sbjct: 430 TDGFVKVLADQATDKILGTHIIGPGAGELINEAVLAMEYGAAAEDVARVCHAHPTCSEAL 489
Query: 480 KEANL-AAYAKPINF 493
+EAN+ AA+ KPINF
Sbjct: 490 REANVAAAFGKPINF 504
>Hs4557525 [C] KOG1335 Dihydrolipoamide dehydrogenase
Length = 509
Score = 522 bits (1344), Expect = e-148
Identities = 265/474 (55%), Positives = 339/474 (70%), Gaps = 11/474 (2%)
Query: 24 DLVVIGGGPGGYVAAIKAAQLGYDVACVEKRGRLGGTCLNVGCIPSKALLNNSHLYHQMK 83
D+ VIG GPGGYVAAIKAAQLG+ C+EK LGGTCLNVGCIPSKALLNNSH YH
Sbjct: 43 DVTVIGSGPGGYVAAIKAAQLGFKTVCIEKNETLGGTCLNVGCIPSKALLNNSHYYHMAH 102
Query: 84 -TDAKQRGIDINGEININVAQFQKAKDTVVKQLTGGIEMLFKKNGVTYYKGLGAFETDKS 142
TD RGI+++ E+ +N+ + + K T VK LTGGI LFK+N V + G G
Sbjct: 103 GTDFASRGIEMS-EVRLNLDKMMEQKSTAVKALTGGIAHLFKQNKVVHVNGYGKITGKNQ 161
Query: 143 VKVLPVEGLEGSVTEDHLLESDRIIVATGSEVTPFPGITIDEERIVSSTGALSLKEIPKK 202
V +G ++++ I++ATGSEVTPFPGITIDE+ IVSSTGALSLK++P+K
Sbjct: 162 VTATKADG------GTQVIDTKNILIATGSEVTPFPGITIDEDTIVSSTGALSLKKVPEK 215
Query: 203 LAXXXXXXXXLEMGSVYSRLGSKVTVIEFQPQIGAT-MDGEVAQTTQKILKKQGLDFKLS 261
+ +E+GSV+ RLG+ VT +EF +G +D E+++ Q+IL+KQG FKL+
Sbjct: 216 MVVIGAGVIGVELGSVWQRLGADVTAVEFLGHVGGVGIDMEISKNFQRILQKQGFKFKLN 275
Query: 262 TKVLSASRNGD-VVDIEVEGAKNGKKESLQADVLLVAVGRRPYVAGLNAEKIGLEVDKRG 320
TKV A++ D +D+ +E A GK E + DVLLV +GRRP+ L E++G+E+D RG
Sbjct: 276 TKVTGATKKSDGKIDVSIEAASGGKAEVITCDVLLVCIGRRPFTKNLGLEELGIELDPRG 335
Query: 321 RLVIDEQLSTKFPHVKVIGDVTFGPMLAHKAEEEGIAAAEYFKVGHGHVNYGNIPAVMYS 380
R+ ++ + TK P++ IGDV GPMLAHKAE+EGI E G H++Y +P+V+Y+
Sbjct: 336 RIPVNTRFQTKIPNIYAIGDVVAGPMLAHKAEDEGIICVEGMAGGAVHIDYNCVPSVIYT 395
Query: 381 HPEVAWVGKTEEQLKEAGIQYKIGKFPFIANSRAKTNMDTEGFVKILIDAESERLLGAHI 440
HPEVAWVGK+EEQLKE GI+YK+GKFPF ANSRAKTN DT+G VKIL ++R+LGAHI
Sbjct: 396 HPEVAWVGKSEEQLKEEGIEYKVGKFPFAANSRAKTNADTDGMVKILGQKSTDRVLGAHI 455
Query: 441 IGPNAGEMIAEAGLALEYGASAEDIARVCHAHPTLSEAFKEANLAA-YAKPINF 493
+GP AGEM+ EA LALEYGAS EDIARVCHAHPTLSEAF+EANLAA + K INF
Sbjct: 456 LGPGAGEMVNEAALALEYGASCEDIARVCHAHPTLSEAFREANLAASFGKSINF 509
>At3g17240 [C] KOG1335 Dihydrolipoamide dehydrogenase
Length = 507
Score = 518 bits (1335), Expect = e-147
Identities = 268/489 (54%), Positives = 347/489 (70%), Gaps = 12/489 (2%)
Query: 4 FNSTRSFSSSALLKTVTKKHDLVVIGGGPGGYVAAIKAAQLGYDVACVEKRGRLGGTCLN 63
F+ TR F+SS + +D+V+IGGGPGGYVAAIKAAQLG C+EKRG LGGTCLN
Sbjct: 30 FSLTRGFASSG-----SDDNDVVIIGGGPGGYVAAIKAAQLGLKTTCIEKRGALGGTCLN 84
Query: 64 VGCIPSKALLNNSHLYHQMKTDAKQRGIDINGEININVAQFQKAKDTVVKQLTGGIEMLF 123
VGCIPSKALL++SH+YH+ K G+ ++ + +++ KDT VK LT G+E LF
Sbjct: 85 VGCIPSKALLHSSHMYHEAKHVFANHGVKVSS-VEVDLPAMLAQKDTAVKNLTRGVEGLF 143
Query: 124 KKNGVTYYKGLGAFETDKSVKVLPVEGLEGSVTEDHLLESDRIIVATGSEVTPFPGITID 183
KKN V Y KG G F + V V ++G E+ +++ IIVATGS+V PGITID
Sbjct: 144 KKNKVNYVKGYGKFLSPSEVSVDTIDG------ENVVVKGKHIIVATGSDVKSLPGITID 197
Query: 184 EERIVSSTGALSLKEIPKKLAXXXXXXXXLEMGSVYSRLGSKVTVIEFQPQIGATMDGEV 243
E++IVSSTGALSL EIPKKL LEMGSV+ RLGS+VTV+EF I MDGE+
Sbjct: 198 EKKIVSSTGALSLTEIPKKLIVIGAGYIGLEMGSVWGRLGSEVTVVEFAADIVPAMDGEI 257
Query: 244 AQTTQKILKKQGLDFKLSTKVLSASRNGDVVDIEVEGAKNGKKESLQADVLLVAVGRRPY 303
+ Q+ L+KQ + F L TKV+ +GD V + VE A+ G++ +L+ADV+LV+ GR P+
Sbjct: 258 RKQFQRSLEKQKMKFMLKTKVVGVDSSGDGVKLIVEPAEGGEQTTLEADVVLVSAGRTPF 317
Query: 304 VAGLNAEKIGLEVDKRGRLVIDEQLSTKFPHVKVIGDVTFGPMLAHKAEEEGIAAAEYFK 363
+GL+ EKIG+E DK GR++++E+ ST V IGDV GPMLAHKAEE+G+A E+
Sbjct: 318 TSGLDLEKIGVETDKGGRILVNERFSTNVSGVYAIGDVIPGPMLAHKAEEDGVACVEFIA 377
Query: 364 VGHGHVNYGNIPAVMYSHPEVAWVGKTEEQLKEAGIQYKIGKFPFIANSRAKTNMDTEGF 423
HGHV+Y +P V+Y++PEVA VGKTEEQLK+ G+ Y +GKFPF+ANSRAK EG
Sbjct: 378 GKHGHVDYDKVPGVVYTYPEVASVGKTEEQLKKEGVSYNVGKFPFMANSRAKAIDTAEGM 437
Query: 424 VKILIDAESERLLGAHIIGPNAGEMIAEAGLALEYGASAEDIARVCHAHPTLSEAFKEAN 483
VKIL D E++++LG HI+ PNAGE+I EA LA+ Y AS+EDIARVCHAHPT+SEA KEA
Sbjct: 438 VKILADKETDKILGVHIMSPNAGELIHEAVLAINYDASSEDIARVCHAHPTMSEAIKEAA 497
Query: 484 LAAYAKPIN 492
+A Y KPI+
Sbjct: 498 MATYDKPIH 506
>At1g48030 [C] KOG1335 Dihydrolipoamide dehydrogenase
Length = 507
Score = 518 bits (1335), Expect = e-147
Identities = 267/489 (54%), Positives = 347/489 (70%), Gaps = 12/489 (2%)
Query: 4 FNSTRSFSSSALLKTVTKKHDLVVIGGGPGGYVAAIKAAQLGYDVACVEKRGRLGGTCLN 63
F+ +R F+SS + ++D+V+IGGGPGGYVAAIKA+QLG C+EKRG LGGTCLN
Sbjct: 30 FSLSRGFASSG-----SDENDVVIIGGGPGGYVAAIKASQLGLKTTCIEKRGALGGTCLN 84
Query: 64 VGCIPSKALLNNSHLYHQMKTDAKQRGIDINGEININVAQFQKAKDTVVKQLTGGIEMLF 123
VGCIPSKALL++SH+YH+ K GI ++ + +++ KD VK LT GIE LF
Sbjct: 85 VGCIPSKALLHSSHMYHEAKHSFANHGIKVSS-VEVDLPAMLAQKDNAVKNLTRGIEGLF 143
Query: 124 KKNGVTYYKGLGAFETDKSVKVLPVEGLEGSVTEDHLLESDRIIVATGSEVTPFPGITID 183
KKN VTY KG G F + V V ++G V H IIVATGS+V PGITID
Sbjct: 144 KKNKVTYVKGYGKFISPNEVSVETIDGGNTIVKGKH------IIVATGSDVKSLPGITID 197
Query: 184 EERIVSSTGALSLKEIPKKLAXXXXXXXXLEMGSVYSRLGSKVTVIEFQPQIGATMDGEV 243
E++IVSSTGALSL E+PKKL LEMGSV+ RLGS+VTV+EF I +MDGE+
Sbjct: 198 EKKIVSSTGALSLSEVPKKLIVIGAGYIGLEMGSVWGRLGSEVTVVEFAGDIVPSMDGEI 257
Query: 244 AQTTQKILKKQGLDFKLSTKVLSASRNGDVVDIEVEGAKNGKKESLQADVLLVAVGRRPY 303
+ Q+ L+KQ + F L TKV+S + D V + VE A+ G++ L+ADV+LV+ GR P+
Sbjct: 258 RKQFQRSLEKQKMKFMLKTKVVSVDSSSDGVKLTVEPAEGGEQSILEADVVLVSAGRTPF 317
Query: 304 VAGLNAEKIGLEVDKRGRLVIDEQLSTKFPHVKVIGDVTFGPMLAHKAEEEGIAAAEYFK 363
+GL+ EKIG+E DK GR++++++ + P V IGDV GPMLAHKAEE+G+A E+
Sbjct: 318 TSGLDLEKIGVETDKAGRILVNDRFLSNVPGVYAIGDVIPGPMLAHKAEEDGVACVEFIA 377
Query: 364 VGHGHVNYGNIPAVMYSHPEVAWVGKTEEQLKEAGIQYKIGKFPFIANSRAKTNMDTEGF 423
HGHV+Y +P V+Y+HPEVA VGKTEEQLK+ G+ Y++GKFPF+ANSRAK + EG
Sbjct: 378 GKHGHVDYDKVPGVVYTHPEVASVGKTEEQLKKEGVSYRVGKFPFMANSRAKAIDNAEGL 437
Query: 424 VKILIDAESERLLGAHIIGPNAGEMIAEAGLALEYGASAEDIARVCHAHPTLSEAFKEAN 483
VKIL D E++++LG HI+ PNAGE+I EA LA+ Y AS+EDIARVCHAHPT+SEA KEA
Sbjct: 438 VKILADKETDKILGVHIMAPNAGELIHEAVLAINYDASSEDIARVCHAHPTMSEALKEAA 497
Query: 484 LAAYAKPIN 492
+A Y KPI+
Sbjct: 498 MATYDKPIH 506
>CE16262 [C] KOG1335 Dihydrolipoamide dehydrogenase
Length = 464
Score = 481 bits (1239), Expect = e-136
Identities = 263/493 (53%), Positives = 327/493 (65%), Gaps = 41/493 (8%)
Query: 2 LRFNSTRSFSSSALLKTVTKKHDLVVIGGGPGGYVAAIKAAQLGYDVACVEKRGRLGGTC 61
L F + F A + T+ DLVVIGGGPGGYVAAIKAAQLG CVEK LGGTC
Sbjct: 9 LPFAKRQFFQVLARNYSNTQDADLVVIGGGPGGYVAAIKAAQLGMKTVCVEKNATLGGTC 68
Query: 62 LNVGCIPSKALLNNSHLYHQMKTDAKQRGIDINGEININVAQFQKAKDTVVKQLTGGIEM 121
LNVGCIPSKALLNNSH H + D RGID +N+ + +AK VKQLTGGI+
Sbjct: 69 LNVGCIPSKALLNNSHYLHMAQHDFAARGIDCTASLNL--PKMMEAKSNSVKQLTGGIKQ 126
Query: 122 LFKKNGVTYYKGLGAFETDKSVKVLPVEGLEGSVTEDHLLESDRIIVATGSEVTPFPGIT 181
LFK N V + +G F T + + +GSV + + I++A+GSEVTPFPGIT
Sbjct: 127 LFKANKVGHVEG---FATIVGPNTVQAKKNDGSV---ETINARNILIASGSEVTPFPGIT 180
Query: 182 IDEERIVSSTGALSLKEIPKKLAXXXXXXXXLEMGSVYSRLGSKVTVIEFQPQIGAT-MD 240
IDE++IVSSTGALSL ++PKK+ LE+GSV+ RLG++VT +EF +G +D
Sbjct: 181 IDEKQIVSSTGALSLGQVPKKMVVIGAGVIGLELGSVWQRLGAEVTAVEFLGHVGGMGID 240
Query: 241 GEVAQTTQKILKKQGLDFKLSTKVLSASRNGDVVDIEVEGAKNGKKESLQADVLLVAVGR 300
GEV++ Q+ L KQG F L+TKV+ AS+NG + +EVEGAK+GKK++L+ D LLV+VGR
Sbjct: 241 GEVSKNFQRSLTKQGFKFLLNTKVMGASQNGSTITVEVEGAKDGKKQTLECDTLLVSVGR 300
Query: 301 RPYVAGLNAEKIGLEVDKRGRLVIDEQLSTKFPHVKVIGDVTFGPMLAHKAEEEGIAAAE 360
RPY GL + +++D RGR+ ++E+ TK P + IGDV GPMLAHKAE+EGI E
Sbjct: 301 RPYTEGLGLSNVQIDLDNRGRVPVNERFQTKVPSIFAIGDVIEGPMLAHKAEDEGILCVE 360
Query: 361 YFKVGHGHVNYGNIPAVMYSHPEVAWVGKTEEQLKEAGIQYKIGKFPFIANSRAKTNMDT 420
G G+ YKIGKFPF+ANSRAKTN D
Sbjct: 361 GIAGG-------------------------------PGVAYKIGKFPFVANSRAKTNNDQ 389
Query: 421 EGFVKILIDAESERLLGAHIIGPNAGEMIAEAGLALEYGASAEDIARVCHAHPTLSEAFK 480
EGFVK+L D +++R+LG HIIGPNAGEMIAEA LA+EYGASAED+ARVCH HPTLSEAF+
Sbjct: 390 EGFVKVLADKQTDRMLGVHIIGPNAGEMIAEATLAMEYGASAEDVARVCHPHPTLSEAFR 449
Query: 481 EANLAAY-AKPIN 492
EANLAAY K IN
Sbjct: 450 EANLAAYCGKAIN 462
>YPL017c [C] KOG1335 Dihydrolipoamide dehydrogenase
Length = 499
Score = 290 bits (742), Expect = 3e-78
Identities = 180/478 (37%), Positives = 270/478 (55%), Gaps = 19/478 (3%)
Query: 23 HDLVVIGGGPGGYVAAIKAAQLGYDVACVEKRGRLGGTCLNVGCIPSKALLNNSHLYH-- 80
+D++VIG GPGG+ AA++A+Q G ACV++R LGG L G +PSK LL S+LY
Sbjct: 18 YDVLVIGCGPGGFTAAMQASQAGLLTACVDQRASLGGAYLVDGAVPSKTLLYESYLYRLL 77
Query: 81 QMKTDAKQRGIDINGEININVAQFQKAKDTVVKQLTGGIEMLFKKNGVTYYKGLGAFETD 140
Q + +QRG + ++ Q A +++L + KN VT YKG AF+
Sbjct: 78 QQQELIEQRGTRLF-PAKFDMQAAQSALKHNIEELGNVYKRELSKNNVTVYKGTAAFKDP 136
Query: 141 KSVKVLPVEGLEGSVTEDHLLESDRIIVATGSEVTPFPGITIDEERIVSSTGALSLKEIP 200
V++ G++ ++E+ I+VATGS V PG+ ID ++I+SS ALSL IP
Sbjct: 137 HHVEIAQ-RGMK-----PFIVEAKYIVVATGSAVIQCPGVAIDNDKIISSDKALSLDYIP 190
Query: 201 KKLAXXXXXXXXLEMGSVYSRLGSKVTVIEFQPQIGATMDGEVAQTTQKILKKQGLDFKL 260
+ LE+ +++ LGS+VT++E Q +I MD E+A T+ +L+ QG+ F L
Sbjct: 191 SRFTIMGGGTIGLEIACIFNNLGSRVTIVESQSEICQNMDNELASATKTLLQCQGIAFLL 250
Query: 261 STKV-LSASRNGDVVDIEVEGAKNGKKESLQADVLLVAVGRRPYVAGLNAEKIGL-EVDK 318
T+V L+ + ++I + + K DVL+V++GRRP + GL+ IGL E D
Sbjct: 251 DTRVQLAEADAAGQLNITLLNKVSKKTYVHHCDVLMVSIGRRPLLKGLDISSIGLDERDF 310
Query: 319 RGRLVIDEQLSTKFPHVKVIGDVTFGPMLAHKAEEEGIAAAEYFKV--GHGHVNYGNIPA 376
+ + Q K+PH+K IGDVT GPMLA KAEE+ I A + G N G P
Sbjct: 311 VENVDVQTQSLLKYPHIKPIGDVTLGPMLALKAEEQAIRAIQSIGCTGSDGTSNCGFPPN 370
Query: 377 VMYSHPEVAWVGKTEEQLKEAGIQYKIGKFPFIANSRAKT------NMDTEGFVKILIDA 430
V+Y P++ WVG TEE L +A I Y+ G+ F N R T N F+K+LID+
Sbjct: 371 VLYCQPQIGWVGYTEEGLAKARIPYQKGRVLFSQNVRYNTLLPREENTTVSPFIKVLIDS 430
Query: 431 ESERLLGAHIIGPNAGEMIAEAGLALEYGASAEDIARVCHAHPTLSEAFKEANLAAYA 488
++LG H+I +A E++++A +A+ G +A D+ +V HP+LSE+FK+A A A
Sbjct: 431 RDMKILGVHMINDDANELLSQASMAVSLGLTAHDVCKVPFPHPSLSESFKQAVQLAMA 488
>At3g16950 [C] KOG1335 Dihydrolipoamide dehydrogenase
Length = 564
Score = 224 bits (570), Expect = 3e-58
Identities = 160/507 (31%), Positives = 258/507 (50%), Gaps = 40/507 (7%)
Query: 2 LRFNSTRSFSSSALLKT-------VTKKHDLVVIGGGPGGYVAAIKAAQLGYDVACVEKR 54
++F S +SF SA + + +DL++IG G GG+ AA+ A + G A +E
Sbjct: 59 IQFLSRKSFQVSASASSNGNGAPPKSFDYDLIIIGAGVGGHGAALHAVEKGLKTAIIEG- 117
Query: 55 GRLGGTCLNVGCIPSKALLNNSHLYHQMKTDAKQRGIDINGEININVAQFQKA-----KD 109
+GGTC+N GC+PSKALL S +++ + + + ++ A + + +
Sbjct: 118 DVVGGTCVNRGCVPSKALLAVSGRMRELQNEHHMKSFGLQ----VSAAGYDRQGVADHAN 173
Query: 110 TVVKQLTGGIEMLFKKNGVTYYKGLGAFETDKSVKVLPVEGLEGSVTEDHLLESDRIIVA 169
+ ++ + K GV G G+ + VK +D+++ + II+A
Sbjct: 174 NLATKIRNNLTNSMKAIGVDILTGFGSVLGPQKVKY----------GKDNIITAKDIIIA 223
Query: 170 TGSEVTPFPGITIDEERIVSSTGALSLKEIPKKLAXXXXXXXXLEMGSVYSRLGSKVTVI 229
TGS GI +D + +++S AL L+ +P+ +A LE VY+ LGS+VT I
Sbjct: 224 TGSVPFVPKGIEVDGKTVITSDHALKLESVPEWIAIVGSGYIGLEFSDVYTALGSEVTFI 283
Query: 230 EFQPQIGATMDGEVAQTTQKIL---KKQGLDFKLSTKVLSASRNGDVVDIEVEGAKNGK- 285
E Q+ D E+++ Q++L +K + ++ +R+G V IE+ AK +
Sbjct: 284 EALDQLMPGFDPEISKLAQRVLINPRKIDYHTGVFASKITPARDGKPVLIELIDAKTKEP 343
Query: 286 KESLQADVLLVAVGRRPYVAGLNAEKIG-LEVDKRGRLVIDEQLSTKFPHVKVIGDVTFG 344
K++L+ D L+A GR P+ GL E G + VD+R R++ + T P++ IGD
Sbjct: 344 KDTLEVDAALIATGRAPFTNGLGLENRGFIPVDERMRVI--DGKGTLVPNLYCIGDANGK 401
Query: 345 PMLAHKAEEEGIAAAEYFKVGHGHV-NYGNIPAVMYSHPEVAWVGKTEEQLKEAG----I 399
MLAH A +GI+ E G HV N+ +IPA ++HPE++ VG TE Q KE G
Sbjct: 402 LMLAHAASAQGISVVEQVS-GRDHVLNHLSIPAACFTHPEISMVGLTEPQAKEKGEKEGF 460
Query: 400 QYKIGKFPFIANSRAKTNMDTEGFVKILIDAESERLLGAHIIGPNAGEMIAEAGLALEYG 459
+ + K F AN++A + EG K++ ++ +LG HI G +A ++I EA A+ G
Sbjct: 461 KVSVVKTSFKANTKALAENEGEGIAKMIYRPDNGEILGVHIFGLHAADLIHEASNAIALG 520
Query: 460 ASAEDIARVCHAHPTLSEAFKEANLAA 486
+DI HAHPTLSE E AA
Sbjct: 521 TRIQDIKLAVHAHPTLSEVLDELFKAA 547
>SPBC17A3.07 [Q] KOG0405 Pyridine nucleotide-disulphide oxidoreductase
Length = 464
Score = 171 bits (432), Expect = 3e-42
Identities = 126/468 (26%), Positives = 223/468 (46%), Gaps = 22/468 (4%)
Query: 19 VTKKHDLVVIGGGPGGYVAAIKAAQLGYDVACVEKRGRLGGTCLNVGCIPSKALLNNSHL 78
++K D +VIGGG GG +A +AA+ G VA +E GRLGGTC+N GC+P K + N + L
Sbjct: 4 ISKVFDYLVIGGGSGGLASARRAAKHGAKVALIEASGRLGGTCVNYGCVPKKIMWNIADL 63
Query: 79 YHQMKTDAKQRGIDINGEININVAQFQKAKDTVVKQLTGGIEMLFKKNGVTYYKGLGAFE 138
+MKT AKQ G + + + ++ +D + +L G E K+GV Y G +F
Sbjct: 64 VAKMKT-AKQNGFPNSQLGSFDWGMIKRKRDAYIGRLNGIYERNVNKDGVAYISGHASFV 122
Query: 139 TDKSVKVLPVEGLEGSVTEDHLLESDRIIVATGSEVTPFPGITIDEERIVSSTGALSLKE 198
+ V V+ +GS T+ + + I++A G +P E + S G L+
Sbjct: 123 SPTEV---AVDMNDGSGTQ--VFSAKYILIAVGGHPI-WPSHIPGAEYGIDSDGFFELES 176
Query: 199 IPKKLAXXXXXXXXLEMGSVYSRLGSKVTVIEFQPQIGATMDGEVAQTTQKILKKQGLDF 258
PK++A +E+ V++ LG++ + Q + D ++ + G++
Sbjct: 177 QPKRVAIVGAGYIAVELAGVFAALGTETHMFIRQSKFLRKFDPIISDGIMDHFQHIGINV 236
Query: 259 ---KLSTKVLSASRNGDVVDIEVEGAKNGKKESLQADVLLVAVGRRPYVAGLNAEKIGLE 315
L K + +G++ + +G+ + D LL A+GR P + GL EK G++
Sbjct: 237 HTNSLEFKKVEKLPSGELCIHQQDGS------TFNVDTLLWAIGRAPKIQGLRLEKAGVK 290
Query: 316 VDKRGRLVIDEQLSTKFPHVKVIGDVTFGPMLAHKAEEEGIAAAE--YFKVGHGHVNYGN 373
G ++ D T P V +GDV L A G ++ + + H++Y
Sbjct: 291 TLPNGIIIADTYQRTNVPTVLSLGDVCGKLELTPVAIAAGRRLSDRLFGGIKDAHLDYEE 350
Query: 374 IPAVMYSHPEVAWVGKTEEQ----LKEAGIQYKIGKFPFIANSRAKTNMDTEGFVKILID 429
+P+V+++HPE +G TE++ E+ I+ KF + S + K++
Sbjct: 351 VPSVVFAHPEAGTIGLTEQEAIDKYGESQIKVYNTKFNGLNYSMVEQEDKVPTTYKLVCA 410
Query: 430 AESERLLGAHIIGPNAGEMIAEAGLALEYGASAEDIARVCHAHPTLSE 477
++++G H++G + E++ G+A++ GA+ D HPT +E
Sbjct: 411 GPLQKVVGLHLVGDFSAEILQGFGVAIKMGATKSDFDSCVAIHPTSAE 458
>YPL091w [Q] KOG0405 Pyridine nucleotide-disulphide oxidoreductase
Length = 483
Score = 167 bits (423), Expect = 3e-41
Identities = 125/473 (26%), Positives = 224/473 (46%), Gaps = 23/473 (4%)
Query: 16 LKTVTKKHDLVVIGGGPGGYVAAIKAAQLGYDVACVEKRGRLGGTCLNVGCIPSKALLNN 75
+ T TK +D +VIGGG GG +A +AA G VE + LGGTC+NVGC+P K +
Sbjct: 17 MSTNTKHYDYLVIGGGSGGVASARRAASYGAKTLLVEAKA-LGGTCVNVGCVPKKVMWYA 75
Query: 76 SHLYHQMKTDAKQRGIDIN-----GEININVAQFQKAKDTVVKQLTGGIEMLFKKNGVTY 130
S L ++ + A + G+ N + N +F++ +D V +L G + +K V
Sbjct: 76 SDLATRV-SHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDV 134
Query: 131 YKGLGAFETDKSVKVLPVEGLEGSVTEDHLLESDRIIVATGSEVTPFPGITIDEERIVSS 190
G F D +V+V + + +H+L VATG + FP E S
Sbjct: 135 VFGWARFNKDGNVEVQKRDNTTEVYSANHIL------VATGGKAI-FPENIPGFELGTDS 187
Query: 191 TGALSLKEIPKKLAXXXXXXXXLEMGSVYSRLGSKVTVIEFQPQIGATMDGEVAQTTQKI 250
G L+E PKK+ +E+ V+ LGS+ ++ + D + T
Sbjct: 188 DGFFRLEEQPKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDH 247
Query: 251 LKKQGLDFKLSTKVLSASRNGDVVDIEVEGAKNGKKESLQADVLLVAVGRRPYVAGLNAE 310
K+G++ +K++ +N + +++ N K D L+ +GR+ ++ G+ +E
Sbjct: 248 YVKEGINVHKLSKIVKVEKNVETDKLKIH--MNDSKSIDDVDELIWTIGRKSHL-GMGSE 304
Query: 311 KIGLEVDKRGRLVIDEQLSTKFPHVKVIGDVTFGPMLAHKAEEEGIAAAEYF----KVGH 366
+G++++ +++ DE +T P++ +GDV L A G + K +
Sbjct: 305 NVGIKLNSHDQIIADEYQNTNVPNIYSLGDVVGKVELTPVAIAAGRKLSNRLFGPEKFRN 364
Query: 367 GHVNYGNIPAVMYSHPEVAWVGKTEEQL--KEAGIQYKIGKFPFIANSRAKTNMDTEGFV 424
++Y N+P+V++SHPE +G +E++ K K+ F A A + +
Sbjct: 365 DKLDYENVPSVIFSHPEAGSIGISEKEAIEKYGKENIKVYNSKFTAMYYAMLSEKSPTRY 424
Query: 425 KILIDAESERLLGAHIIGPNAGEMIAEAGLALEYGASAEDIARVCHAHPTLSE 477
KI+ +E+++G HI+G ++ E++ G+A++ GA+ D HPT +E
Sbjct: 425 KIVCAGPNEKVVGLHIVGDSSAEILQGFGVAIKMGATKADFDNCVAIHPTSAE 477
>Hs10835189 [Q] KOG0405 Pyridine nucleotide-disulphide oxidoreductase
Length = 479
Score = 166 bits (419), Expect = 1e-40
Identities = 126/463 (27%), Positives = 220/463 (47%), Gaps = 19/463 (4%)
Query: 23 HDLVVIGGGPGGYVAAIKAAQLGYDVACVEKRGRLGGTCLNVGCIPSKALLNNSHLYHQM 82
+D +VIGGG GG +A +AA+LG A VE +LGGTC+NVGC+P K + N + M
Sbjct: 22 YDYLVIGGGSGGLASARRAAELGARAAVVESH-KLGGTCVNVGCVPKKVMWNTAVHSEFM 80
Query: 83 KTDAKQRGIDINGEININVAQFQKAKDTVVKQLTGGIEMLFKKNGVTYYKGLGAFETDKS 142
A G+ N V ++ +D V +L + K+ + +G AF +D
Sbjct: 81 HDHADYGFPSCEGKFNWRV--IKEKRDAYVSRLNAIYQNNLTKSHIEIIRGHAAFTSDPK 138
Query: 143 VKVLPVEGLEGSVTEDHLLESDRIIVATGSEVTPFPGITIDEERIVSSTGALSLKEIPKK 202
+ V G + T H+L + + +T E + PG ++ ++S G L+E+P +
Sbjct: 139 -PTIEVSGKK--YTAPHILIATGGMPSTPHE-SQIPGASLG----ITSDGFFQLEELPGR 190
Query: 203 LAXXXXXXXXLEMGSVYSRLGSKVTVIEFQPQIGATMDGEVAQTTQKILKKQGLDFKLST 262
+EM + S LGSK +++ ++ + D ++ + L+ G++ +
Sbjct: 191 SVIVGAGYIAVEMAGILSALGSKTSLMIRHDKVLRSFDSMISTNCTEELENAGVEVLKFS 250
Query: 263 KVLSASRNGDVVDIEVEGAKNGKKESL----QADVLLVAVGRRPYVAGLNAEKIGLEVDK 318
+V + +++ + A G+ + D LL A+GR P L+ K+G++ D
Sbjct: 251 QVKEVKKTLSGLEVSMVTAVPGRLPVMTMIPDVDCLLWAIGRVPNTKDLSLNKLGIQTDD 310
Query: 319 RGRLVIDEQLSTKFPHVKVIGDVTFGPMLAHKAEEEG--IAAAEYFKVGHGHVNYGNIPA 376
+G +++DE +T + +GDV +L A G +A + ++Y NIP
Sbjct: 311 KGHIIVDEFQNTNVKGIYAVGDVCGKALLTPVAIAAGRKLAHRLFEYKEDSKLDYNNIPT 370
Query: 377 VMYSHPEVAWVGKTE-EQLKEAGIQ-YKIGKFPFIANSRAKTNMDTEGFVKILIDAESER 434
V++SHP + VG TE E + + GI+ K F A T T+ +K++ + E+
Sbjct: 371 VVFSHPPIGTVGLTEDEAIHKYGIENVKTYSTSFTPMYHAVTKRKTKCVMKMVCANKEEK 430
Query: 435 LLGAHIIGPNAGEMIAEAGLALEYGASAEDIARVCHAHPTLSE 477
++G H+ G EM+ +A++ GA+ D HPT SE
Sbjct: 431 VVGIHMQGLGCDEMLQGFAVAVKMGATKADFDNTVAIHPTSSE 473
>CE17558 [Q] KOG0405 Pyridine nucleotide-disulphide oxidoreductase
Length = 473
Score = 162 bits (409), Expect = 1e-39
Identities = 135/490 (27%), Positives = 221/490 (44%), Gaps = 42/490 (8%)
Query: 1 MLRFNSTRSFSSSALLKTVTKKHDLVVIGGGPGGYVAAIKAAQLGYDVACVEKRGRLGGT 60
MLRF S S S + + K+ D +VIGGG GG +A +A + G V +E GRLGGT
Sbjct: 1 MLRFRCILSTSRSIM--SGVKEFDYLVIGGGSGGIASARRAREFGVSVGLIES-GRLGGT 57
Query: 61 CLNVGCIPSKALLNNSHLYHQMKTDAKQRGIDINGEININVAQFQKAKDTVVKQLTGGIE 120
C+NVGC+P K + N S L+ + D G D+ + +K++D +K+L G E
Sbjct: 58 CVNVGCVPKKVMYNCS-LHAEFIRDHADYGFDVTLN-KFDWKVIKKSRDEYIKRLNGLYE 115
Query: 121 MLFKKNGVTYYKGLGAFETDKSVKVLPVEGLEGSVTEDHLLESDRIIVATGSEVTPFPGI 180
K + V Y +G F D +V+V + ++A G + T P I
Sbjct: 116 SGLKGSSVEYIRGRATFAEDGTVEVNGAK-----------YRGKNTLIAVGGKPT-IPNI 163
Query: 181 TIDEERIVSSTGALSLKEIPKKLAXXXXXXXXLEMGSVYSRLGSKVTVIEFQPQIGATMD 240
E + S G L+++P + +E+ V + LGS ++ ++ T D
Sbjct: 164 K-GAEHGIDSDGFFDLEDLPSRTVVVGAGYIAVEIAGVLANLGSDTHLLIRYDKVLRTFD 222
Query: 241 GEVAQTTQKILKKQ-GLDFKLSTKVLSASRNGDVVDIEVEG--------AKNGKKESLQA 291
K+L + D T L +N V ++ ++G G E +Q
Sbjct: 223 --------KMLSDELTADMDEETNPLHLHKNTQVTEV-IKGDDGLLTIKTTTGVIEKVQT 273
Query: 292 DVLLVAVGRRPYVAGLNAEKIGLEVDKRGRLVIDEQLSTKFPHVKVIGDVTFGPMLAHKA 351
L+ A+GR P LN E++G++ DK G +++DE +T P + +GD T +L A
Sbjct: 274 --LIWAIGRDPLTKELNLERVGVKTDKSGHIIVDEYQNTSAPGILSVGDDTGKFLLTPVA 331
Query: 352 EEEGIAAAEYFKVGH--GHVNYGNIPAVMYSHPEVAWVGKTEEQL--KEAGIQYKIGKFP 407
G + G + Y NI V++SHP + VG TE + K + + K
Sbjct: 332 IAAGRRLSHRLFNGETDNKLTYENIATVVFSHPLIGTVGLTEAEAVEKYGKDEVTLYKSR 391
Query: 408 FIANSRAKTNMDTEGFVKILIDAESERLLGAHIIGPNAGEMIAEAGLALEYGASAEDIAR 467
F A T + +K++ + E+++G H+ G + EM+ +A+ GA+ + +
Sbjct: 392 FNPMLFAVTKHKEKAAMKLVCVGKDEKVVGVHVFGVGSDEMLQGFAVAVTMGATKKQFDQ 451
Query: 468 VCHAHPTLSE 477
HPT +E
Sbjct: 452 TVAIHPTSAE 461
>At3g24170 [Q] KOG0405 Pyridine nucleotide-disulphide oxidoreductase
Length = 499
Score = 152 bits (384), Expect = 1e-36
Identities = 123/467 (26%), Positives = 211/467 (44%), Gaps = 25/467 (5%)
Query: 24 DLVVIGGGPGGYVAAIKAAQLGYDVACVE---------KRGRLGGTCLNVGCIPSKALLN 74
DL VIG G GG AA +A G V E + G +GGTC+ GC+P K L+
Sbjct: 27 DLFVIGAGSGGVRAARFSANHGAKVGICELPFHPISSEEIGGVGGTCVIRGCVPKKILVY 86
Query: 75 NSHLYHQMKTDAKQRGIDINGEININVAQFQKAKDTVVKQLTGGIEMLFKKNGVTYYKGL 134
+ +++ DAK G +IN +++ + + K + +L + L V Y+G
Sbjct: 87 GATYGGELE-DAKNYGWEINEKVDFTWKKLLQKKTDEILRLNNIYKRLLANAAVKLYEGE 145
Query: 135 GAFETDKSVKVLPVEGLEGSVTEDHLLESDRIIVATGSEVTPFPGITIDEERIVSSTGAL 194
G V+V ++G + S T H+L +ATGS P I E ++S AL
Sbjct: 146 GRVVGPNEVEVRQIDGTKISYTAKHIL------IATGSRAQK-PNIP-GHELAITSDEAL 197
Query: 195 SLKEIPKKLAXXXXXXXXLEMGSVYSRLGSKVTVIEFQPQIGATMDGEVAQTTQKILKKQ 254
SL+E PK+ +E S++ +G+ V + + D E+ + L+ +
Sbjct: 198 SLEEFPKRAIVLGGGYIAVEFASIWRGMGATVDLFFRKELPLRGFDDEMRALVARNLEGR 257
Query: 255 GLDFKLSTKVLSASRNGDVVDIEVEGAKNGKKESLQADVLLVAVGRRPYVAGLNAEKIGL 314
G++ T + ++ + + + E ADV+L A GR P LN E +G+
Sbjct: 258 GVNLHPQTSLTQLTKTDQGIKVI-----SSHGEEFVADVVLFATGRSPNTKRLNLEAVGV 312
Query: 315 EVDKRGRLVIDEQLSTKFPHVKVIGDVTFGPMLAHKAEEEGIAAAE-YFKVGHGHVNYGN 373
E+D+ G + +DE T P + +GD T L A E A F Y N
Sbjct: 313 ELDQAGAVKVDEYSRTNIPSIWAVGDATNRINLTPVALMEATCFANTAFGGKPTKAEYSN 372
Query: 374 IPAVMYSHPEVAWVGKTEEQ-LKEAGIQYKIGKFPFIANSRAKTNMDTEGFVKILIDAES 432
+ ++ P +A VG +EE+ +++A + F + + +K+++D +S
Sbjct: 373 VACAVFCIPPLAVVGLSEEEAVEQATGDILVFTSGFNPMKNTISGRQEKTLMKLIVDEKS 432
Query: 433 ERLLGAHIIGPNAGEMIAEAGLALEYGASAEDIARVCHAHPTLSEAF 479
++++GA + GP+A E++ +AL+ GA+ HP+ +E F
Sbjct: 433 DKVIGASMCGPDAAEIMQGIAIALKCGATKAQFDSTVGIHPSSAEEF 479
>Hs22035672 [O] KOG4716 Thioredoxin reductase
Length = 524
Score = 145 bits (365), Expect = 2e-34
Identities = 133/479 (27%), Positives = 211/479 (43%), Gaps = 36/479 (7%)
Query: 21 KKHDLVVIGGGPGGYVAAIKAAQLGYDVACVE--------KRGRLGGTCLNVGCIPSKAL 72
+ +DL+V+GGG GG A +AAQLG VA V+ R LGGTC+NVGCIP K L
Sbjct: 38 RDYDLLVVGGGSGGLACAKEAAQLGRKVAVVDYVEPSPQGTRWGLGGTCVNVGCIPKK-L 96
Query: 73 LNNSHLYHQMKTDAKQRGIDINGEININVAQFQKAKDTVVKQLTGGIEMLFKKNGVTYYK 132
++ + L + DA G ++ + + + +A VK L G + + V Y+
Sbjct: 97 MHQAALLGGLIQDAPNYGWEVAQPVPHDWRKMAEAVQNHVKSLNWGHRVQLQDRKVKYFN 156
Query: 133 GLGAFETDKSVKVLPVEGLEGSVTEDHLLESDRIIVATGSEVTPFPGITIDEERIVSSTG 192
+F + +V + G E LL +D II+ATG I E ++S
Sbjct: 157 IKASFVDEHTVCGVAKGGKE------ILLSADHIIIATGGRPRYPTHIEGALEYGITSDD 210
Query: 193 ALSLKEIPKKLAXXXXXXXXLEMGSVYSRLGSKVTVIEFQPQIGATMDGEVAQTTQKILK 252
LKE P K LE + +G T++ + D +++ + +
Sbjct: 211 IFWLKESPGKTLVVGASYVALECAGFLTGIGLDTTIMMRSIPLRG-FDQQMSSMVIEHMA 269
Query: 253 KQGLDFKLSTKVLSASRNGD-VVDIEVEGAKNGKKESLQADVLLVAVGRRPYVAGLNAEK 311
G F R D + + E + GK+++ D +L A+GR P LN EK
Sbjct: 270 SHGTRFLRGCAPSRVRRLPDGQLQVTWEDSTTGKEDTGTFDTVLWAIGRVPDTRSLNLEK 329
Query: 312 IGLEVDK-RGRLVIDEQLSTKFPHVKVIGDVTFG-PMLAHKAEEEG-IAAAEYFKVGHGH 368
G++ ++++D + +T PH+ IGDV G P L A G + F
Sbjct: 330 AGVDTSPDTQKILVDSREATSVPHIYAIGDVVEGRPELTPIAIMAGRLLVQRLFGGSSDL 389
Query: 369 VNYGNIPAVMYSHPEVAWVGKTEEQ---------LKEAGIQYKIGKFPFIANSRAKTNMD 419
++Y N+P +++ E VG +EE+ ++ YK +F ++
Sbjct: 390 MDYDNVPTTVFTPLEYGCVGLSEEEAVARHGQEHVEVYHAHYKPLEFTVAGRDASQC--- 446
Query: 420 TEGFVKILIDAESERL-LGAHIIGPNAGEMIAEAGLALEYGASAEDIARVCHAHPTLSE 477
+VK++ E +L LG H +GPNAGE+ L ++ GAS + R HPT SE
Sbjct: 447 ---YVKMVCLREPPQLVLGLHFLGPNAGEVTQGFALGIKCGASYAQVMRTVGIHPTCSE 502
>Hs22035670 [O] KOG4716 Thioredoxin reductase
Length = 494
Score = 145 bits (365), Expect = 2e-34
Identities = 133/479 (27%), Positives = 211/479 (43%), Gaps = 36/479 (7%)
Query: 21 KKHDLVVIGGGPGGYVAAIKAAQLGYDVACVE--------KRGRLGGTCLNVGCIPSKAL 72
+ +DL+V+GGG GG A +AAQLG VA V+ R LGGTC+NVGCIP K L
Sbjct: 8 RDYDLLVVGGGSGGLACAKEAAQLGRKVAVVDYVEPSPQGTRWGLGGTCVNVGCIPKK-L 66
Query: 73 LNNSHLYHQMKTDAKQRGIDINGEININVAQFQKAKDTVVKQLTGGIEMLFKKNGVTYYK 132
++ + L + DA G ++ + + + +A VK L G + + V Y+
Sbjct: 67 MHQAALLGGLIQDAPNYGWEVAQPVPHDWRKMAEAVQNHVKSLNWGHRVQLQDRKVKYFN 126
Query: 133 GLGAFETDKSVKVLPVEGLEGSVTEDHLLESDRIIVATGSEVTPFPGITIDEERIVSSTG 192
+F + +V + G E LL +D II+ATG I E ++S
Sbjct: 127 IKASFVDEHTVCGVAKGGKE------ILLSADHIIIATGGRPRYPTHIEGALEYGITSDD 180
Query: 193 ALSLKEIPKKLAXXXXXXXXLEMGSVYSRLGSKVTVIEFQPQIGATMDGEVAQTTQKILK 252
LKE P K LE + +G T++ + D +++ + +
Sbjct: 181 IFWLKESPGKTLVVGASYVALECAGFLTGIGLDTTIMMRSIPLRG-FDQQMSSMVIEHMA 239
Query: 253 KQGLDFKLSTKVLSASRNGD-VVDIEVEGAKNGKKESLQADVLLVAVGRRPYVAGLNAEK 311
G F R D + + E + GK+++ D +L A+GR P LN EK
Sbjct: 240 SHGTRFLRGCAPSRVRRLPDGQLQVTWEDSTTGKEDTGTFDTVLWAIGRVPDTRSLNLEK 299
Query: 312 IGLEVDK-RGRLVIDEQLSTKFPHVKVIGDVTFG-PMLAHKAEEEG-IAAAEYFKVGHGH 368
G++ ++++D + +T PH+ IGDV G P L A G + F
Sbjct: 300 AGVDTSPDTQKILVDSREATSVPHIYAIGDVVEGRPELTPIAIMAGRLLVQRLFGGSSDL 359
Query: 369 VNYGNIPAVMYSHPEVAWVGKTEEQ---------LKEAGIQYKIGKFPFIANSRAKTNMD 419
++Y N+P +++ E VG +EE+ ++ YK +F ++
Sbjct: 360 MDYDNVPTTVFTPLEYGCVGLSEEEAVARHGQEHVEVYHAHYKPLEFTVAGRDASQC--- 416
Query: 420 TEGFVKILIDAESERL-LGAHIIGPNAGEMIAEAGLALEYGASAEDIARVCHAHPTLSE 477
+VK++ E +L LG H +GPNAGE+ L ++ GAS + R HPT SE
Sbjct: 417 ---YVKMVCLREPPQLVLGLHFLGPNAGEVTQGFALGIKCGASYAQVMRTVGIHPTCSE 472
>HsM5454136 [O] KOG4716 Thioredoxin reductase
Length = 524
Score = 144 bits (362), Expect = 4e-34
Identities = 132/479 (27%), Positives = 211/479 (43%), Gaps = 36/479 (7%)
Query: 21 KKHDLVVIGGGPGGYVAAIKAAQLGYDVACVE--------KRGRLGGTCLNVGCIPSKAL 72
+ +DL+V+GGG GG A +AAQLG V+ V+ R LGGTC+NVGCIP K L
Sbjct: 38 RDYDLLVVGGGSGGLACAKEAAQLGRKVSVVDYVEPSPQGTRWGLGGTCVNVGCIPKK-L 96
Query: 73 LNNSHLYHQMKTDAKQRGIDINGEININVAQFQKAKDTVVKQLTGGIEMLFKKNGVTYYK 132
++ + L + DA G ++ + + + +A VK L G + + V Y+
Sbjct: 97 MHQAALLGGLIQDAPNYGWEVAQPVPHDWRKMAEAVQNHVKSLNWGHRVQLQDRKVKYFN 156
Query: 133 GLGAFETDKSVKVLPVEGLEGSVTEDHLLESDRIIVATGSEVTPFPGITIDEERIVSSTG 192
+F + +V + G E LL +D II+ATG I E ++S
Sbjct: 157 IKASFVDEHTVCGVAKGGKE------ILLSADHIIIATGGRPRYPTHIEGALEYGITSDD 210
Query: 193 ALSLKEIPKKLAXXXXXXXXLEMGSVYSRLGSKVTVIEFQPQIGATMDGEVAQTTQKILK 252
LKE P K LE + +G T++ + D +++ + +
Sbjct: 211 IFWLKESPGKTLVVGASYVALECAGFLTGIGLDTTIMMRSIPLRG-FDQQMSSMVIEHMA 269
Query: 253 KQGLDFKLSTKVLSASRNGD-VVDIEVEGAKNGKKESLQADVLLVAVGRRPYVAGLNAEK 311
G F R D + + E + GK+++ D +L A+GR P LN EK
Sbjct: 270 SHGTRFLRGCAPSRVRRLPDGQLQVTWEDSTTGKEDTGTFDTVLWAIGRVPDTRSLNLEK 329
Query: 312 IGLEVDK-RGRLVIDEQLSTKFPHVKVIGDVTFG-PMLAHKAEEEG-IAAAEYFKVGHGH 368
G++ ++++D + +T PH+ IGDV G P L A G + F
Sbjct: 330 AGVDTSPDTQKILVDSREATSVPHIYAIGDVVEGRPELTPIAIMAGRLLVQRLFGGSSDL 389
Query: 369 VNYGNIPAVMYSHPEVAWVGKTEEQ---------LKEAGIQYKIGKFPFIANSRAKTNMD 419
++Y N+P +++ E VG +EE+ ++ YK +F ++
Sbjct: 390 MDYDNVPTTVFTPLEYGCVGLSEEEAVARHGQEHVEVYHAHYKPLEFTVAGRDASQC--- 446
Query: 420 TEGFVKILIDAESERL-LGAHIIGPNAGEMIAEAGLALEYGASAEDIARVCHAHPTLSE 477
+VK++ E +L LG H +GPNAGE+ L ++ GAS + R HPT SE
Sbjct: 447 ---YVKMVCLREPPQLVLGLHFLGPNAGEVTQGFALGIKCGASYAQVMRTVGIHPTCSE 502
>At3g54660 [Q] KOG0405 Pyridine nucleotide-disulphide oxidoreductase
Length = 565
Score = 138 bits (347), Expect = 2e-32
Identities = 120/466 (25%), Positives = 200/466 (42%), Gaps = 28/466 (6%)
Query: 24 DLVVIGGGPGGYVAAIKAAQLGYDVACVE---------KRGRLGGTCLNVGCIPSKALLN 74
DL IG G GG A+ A G A E G +GGTC+ GC+P K L+
Sbjct: 89 DLFTIGAGSGGVRASRFATSFGASAAVCELPFSTISSDTAGGVGGTCVLRGCVPKKLLVY 148
Query: 75 NSHLYHQMKTDAKQRGIDINGEININVAQFQKAKDTVVKQLTGGIEMLFKKNGVTYYKGL 134
S H+ + D+ G E + + K+ +++LTG + + K V +G
Sbjct: 149 ASKYSHEFE-DSHGFGWKYETEPSHDWTTLIANKNAELQRLTGIYKNILSKANVKLIEGR 207
Query: 135 GAFETDKSVKVLPVEGLEGSVTEDHLLESDRIIVATGSEVTPFPGITIDEERIVSSTGAL 194
G +V V + + + I++A G PF +E + S AL
Sbjct: 208 GKVIDPHTVDV-----------DGKIYTTRNILIAVGGR--PFIPDIPGKEFAIDSDAAL 254
Query: 195 SLKEIPKKLAXXXXXXXXLEMGSVYSRLGSKVTVIEFQPQIGATMDGEVAQTTQKILKKQ 254
L PKK+A LE +++ L +V V Q ++ D +V + + +
Sbjct: 255 DLPSKPKKIAIVGGGYIALEFAGIFNGLNCEVHVFIRQKKVLRGFDEDVRDFVGEQMSLR 314
Query: 255 GLDFKLSTKVLSASRNGDVVDIEVEGAKNGKKESLQADVLLVAVGRRPYVAGLNAEKIGL 314
G++F + + GD ++ +K G E ++ A GR+P L E +G+
Sbjct: 315 GIEFHTEESPEAIIKAGDG-SFSLKTSK-GTVEGFSH--VMFATGRKPNTKNLGLENVGV 370
Query: 315 EVDKRGRLVIDEQLSTKFPHVKVIGDVTFGPMLAHKAEEEGIAAAE-YFKVGHGHVNYGN 373
++ K G + +DE T P + +GDVT L A EG A A+ F+ +Y
Sbjct: 371 KMAKNGAIEVDEYSQTSVPSIWAVGDVTDRINLTPVALMEGGALAKTLFQNEPTKPDYRA 430
Query: 374 IPAVMYSHPEVAWVGKTEEQLKEAGIQYKIGKFPFIANSRAKTNMDTEGFVKILIDAESE 433
+P ++S P + VG TEEQ E + F + + F+K+++ A +
Sbjct: 431 VPCAVFSQPPIGTVGLTEEQAIEQYGDVDVYTSNFRPLKATLSGLPDRVFMKLIVCANTN 490
Query: 434 RLLGAHIIGPNAGEMIAEAGLALEYGASAEDIARVCHAHPTLSEAF 479
++LG H+ G ++ E+I G+A++ G + D HPT +E F
Sbjct: 491 KVLGVHMCGEDSPEIIQGFGVAVKAGLTKADFDATVGVHPTAAEEF 536
>Hs4507747 [O] KOG4716 Thioredoxin reductase
Length = 497
Score = 133 bits (335), Expect = 5e-31
Identities = 118/481 (24%), Positives = 217/481 (44%), Gaps = 38/481 (7%)
Query: 23 HDLVVIGGGPGGYVAAIKAAQLGYDVACVE--------KRGRLGGTCLNVGCIPSKALLN 74
+DL++IGGG GG AA +AAQ G V ++ R LGGTC+NVGCIP K L++
Sbjct: 13 YDLIIIGGGSGGLAAAKEAAQYGKKVMVLDFVTPTPLGTRWGLGGTCVNVGCIPKK-LMH 71
Query: 75 NSHLYHQMKTDAKQRGIDINGEININVAQFQKAKDTVVKQLTGGIEMLFKKNGVTYYKGL 134
+ L Q D++ G + + + + +A + L G + ++ V Y
Sbjct: 72 QAALLGQALQDSRNYGWKVEETVKHDWDRMIEAVQNHIGSLNWGYRVALREKKVVYENAY 131
Query: 135 GAFETDKSVKVLPVEGLEGSVTEDHLLESDRIIVATGSEVTPFPGITIDEERIVSSTGAL 194
G F +K +G E + ++ ++ATG E + GI D+E +SS
Sbjct: 132 GQFIGPHRIKATNNKGKE------KIYSAESFLIATG-ERPRYLGIPGDKEYCISSDDLF 184
Query: 195 SLKEIPKKLAXXXXXXXXLEMGSVYSRLGSKVTVIEFQPQIGATMDGEVAQTTQKILKKQ 254
SL P K LE + +G VTV+ + + D ++A + +++
Sbjct: 185 SLPYCPGKTLVVGASYVALECAGFLAGIGLGVTVM-VRSILLRGFDQDMANKIGEHMEEH 243
Query: 255 GLDF-----KLSTKVLSASRNGDVVDIEVEGAKNGKKESLQAD--VLLVAVGRRPYVAGL 307
G+ F + + + A G + V +E ++ + +++A+GR +
Sbjct: 244 GIKFIRQFVPIKVEQIEAGTPGR---LRVVAQSTNSEEIIEGEYNTVMLAIGRDACTRKI 300
Query: 308 NAEKIGLEV-DKRGRLVIDEQLSTKFPHVKVIGDVTFGPM-LAHKAEEEGIAAAEYFKVG 365
E +G+++ +K G++ + ++ T P++ IGD+ + L A + G A+ G
Sbjct: 301 GLETVGVKINEKTGKIPVTDEEQTNVPYIYAIGDILEDKVELTPVAIQAGRLLAQRLYAG 360
Query: 366 HG-HVNYGNIPAVMYSHPEVAWVGKTEEQLKEAGIQYKIGKF-----PFIANSRAKTNMD 419
+Y N+P +++ E G +EE+ E + I + P ++ N
Sbjct: 361 STVKCDYENVPTTVFTPLEYGACGLSEEKAVEKFGEENIEVYHSYFWPLEWTIPSRDN-- 418
Query: 420 TEGFVKILIDA-ESERLLGAHIIGPNAGEMIAEAGLALEYGASAEDIARVCHAHPTLSEA 478
+ + KI+ + ++ER++G H++GPNAGE+ AL+ G + + + HP +E
Sbjct: 419 NKCYAKIICNTKDNERVVGFHVLGPNAGEVTQGFAAALKCGLTKKQLDSTIGIHPVCAEV 478
Query: 479 F 479
F
Sbjct: 479 F 479
>CE26906 [O] KOG4716 Thioredoxin reductase
Length = 665
Score = 132 bits (332), Expect = 1e-30
Identities = 132/495 (26%), Positives = 210/495 (41%), Gaps = 49/495 (9%)
Query: 23 HDLVVIGGGPGGYVAAIKAAQLGYDVACVE--------KRGRLGGTCLNVGCIPSKALLN 74
+DL+VIGGG GG AA +A++LG VAC++ LGGTC+NVGCIP K +
Sbjct: 173 YDLIVIGGGSGGLAAAKEASRLGKKVACLDFVKPSPQGTSWGLGGTCVNVGCIPKKLMHQ 232
Query: 75 NSHLYHQMKTDAKQRGIDI-NGEININVAQFQKAKDTVVKQLTGGIEMLFKKNGVTYYKG 133
S L H + DAK+ G + G++ + + + L G + ++ VTY
Sbjct: 233 ASLLGHSIH-DAKKYGWKLPEGKVEHQWNHLRDSVQDHIASLNWGYRVQLREKTVTYINS 291
Query: 134 LGAFE-------TDKSVKVLPVEGLEGSVTEDHLLESDRIIVATGSEVTPFPGITIDEER 186
G F T+K KV L +DR +++TG +P I +E
Sbjct: 292 YGEFTGPFEISATNKKKKV-------------EKLTADRFLISTGLR-PKYPEIPGVKEY 337
Query: 187 IVSSTGALSLKEIPKKLAXXXXXXXXLEMGSVYSRLGSKVTVIEFQPQIGATMDGEVAQT 246
++S L P K LE G VTV+ + + D ++A+
Sbjct: 338 TITSDDLFQLPYSPGKTLCVGASYVSLECAGFLHGFGFDVTVM-VRSILLRGFDQDMAER 396
Query: 247 TQKILKKQGLDFK--LSTKVLSASRNGDV------VDIEVEGAKNGKKESLQAD--VLLV 296
+K + G+ F+ + T++ D V + + G+ + + + +L+
Sbjct: 397 IRKHMIAYGMKFEAGVPTRIEQIDEKTDEKAGKYRVFWPKKNEETGEMQEVSEEYNTILM 456
Query: 297 AVGRRPYVAGLNAEKIGLEVDKRGRLVIDEQLSTKFPHVKVIGDVTFG-PMLAHKAEEEG 355
A+GR + IG+E K +++ + ST P V IGDV G P L A + G
Sbjct: 457 AIGREAVTDDVGLTTIGVERAKSKKVLGRREQSTTIPWVYAIGDVLEGTPELTPVAIQAG 516
Query: 356 -IAAAEYFKVGHGHVNYGNIPAVMYSHPEVAWVGKTEEQL-----KEAGIQYKIGKFPFI 409
+ F + Y IP +++ E G +EE K+ I Y P
Sbjct: 517 RVLMRRIFDGANELTEYDQIPTTVFTPLEYGCCGLSEEDAMMKYGKDNIIIYHNVFNPLE 576
Query: 410 ANSRAKTNMDTEGFVKILIDAESERLLGAHIIGPNAGEMIAEAGLALEYGASAEDIARVC 469
+ + D I + E E+++G HI+ PNAGE+ G+AL+ A D R+
Sbjct: 577 YTISERMDKDHCYLKMICLRNEEEKVVGFHILTPNAGEVTQGFGIALKLAAKKADFDRLI 636
Query: 470 HAHPTLSEAFKEANL 484
HPT++E F L
Sbjct: 637 GIHPTVAENFTTLTL 651
>Hs20536269 [O] KOG4716 Thioredoxin reductase
Length = 459
Score = 126 bits (316), Expect = 8e-29
Identities = 109/434 (25%), Positives = 194/434 (44%), Gaps = 20/434 (4%)
Query: 57 LGGTCLNVGCIPSKALLNNSHLYHQMKTDAKQRGIDINGEININVAQFQKAKDTVVKQLT 116
LGGTC+NVGCIP K L++ + L Q D+++ G + N ++ N KA + L
Sbjct: 17 LGGTCVNVGCIPKK-LMHQAALLGQALCDSRKFGWEYNQQVRHNWETMTKAIQNHISSLN 75
Query: 117 GGIEMLFKKNGVTYYKGLGAFETDKSVKVLPVEGLEGSVTEDHLLESDRIIVATGSEVTP 176
G + ++ V Y G F +K +G E T + + ++ATG E
Sbjct: 76 WGYRLSLREKAVAYVNSYGEFVEHHKIKATNKKGQETYYT------AAQFVIATG-ERPR 128
Query: 177 FPGITIDEERIVSSTGALSLKEIPKKLAXXXXXXXXLEMGSVYSRLGSKVTVIEFQPQIG 236
+ GI D+E ++S SL P K LE + G VTV+ + +
Sbjct: 129 YLGIQGDKEYCITSDDLFSLPYCPGKTLVVGASYVALECAGFLAGFGLDVTVM-VRSILL 187
Query: 237 ATMDGEVAQTTQKILKKQGLDF--KLSTKVLSASRNGDVVDIEVEGAKNGKKESLQA--D 292
D E+A+ +++ G+ F K ++ G ++V E+++ +
Sbjct: 188 RGFDQEMAEKVGSYMEQHGVKFLRKFIPVMVQQLEKGSPGKLKVLAKSTEGTETIEGVYN 247
Query: 293 VLLVAVGRRPYVAGLNAEKIGLEV-DKRGRLVIDEQLSTKFPHVKVIGDVTFG-PMLAHK 350
+L+A+GR + EKIG+++ +K G++ +++ T P+V +GD+ P L
Sbjct: 248 TVLLAIGRDSCTRKIGLEKIGVKINEKSGKIPVNDVEQTNVPYVYAVGDILEDKPELTPV 307
Query: 351 AEEEG-IAAAEYFKVGHGHVNYGNIPAVMYSHPEVAWVGKTEEQLKEAGIQYKIGKFPFI 409
A + G + A F +Y N+P +++ E G +EE+ E + + + +
Sbjct: 308 AIQSGKLLAQRLFGASLEKCDYINVPTTVFTPLEYGCCGLSEEKAIEVYKKENLEIYHTL 367
Query: 410 ANSRAKTNMDTEG---FVKILIDA-ESERLLGAHIIGPNAGEMIAEAGLALEYGASAEDI 465
T E + KI+ + + +R++G HI+GPNAGE+ A++ G + + +
Sbjct: 368 FWPLEWTVAGRENNTCYAKIICNKFDHDRVIGFHILGPNAGEVTQGFAAAMKCGLTKQLL 427
Query: 466 ARVCHAHPTLSEAF 479
HPT E F
Sbjct: 428 DDTIGIHPTCGEVF 441
>7290913 [O] KOG4716 Thioredoxin reductase
Length = 491
Score = 125 bits (313), Expect = 2e-28
Identities = 120/479 (25%), Positives = 215/479 (44%), Gaps = 39/479 (8%)
Query: 23 HDLVVIGGGPGGYVAAIKAAQLGYDVACVE---------KRGRLGGTCLNVGCIPSKALL 73
+DL+VIGGG G A +A G VAC++ + +GGTC+NVGCIP K L+
Sbjct: 10 YDLIVIGGGSAGLACAKEAVLNGARVACLDFVKPTPTLGTKWGVGGTCVNVGCIPKK-LM 68
Query: 74 NNSHLYHQMKTDAKQRGIDINGEININVAQFQKAKDTVVKQLTGGIEMLFKKNGVTYYKG 133
+ + L + +A G +++ +I + + ++ +K + + + V Y G
Sbjct: 69 HQASLLGEAVHEAAAYGWNVDEKIKPDWHKLVQSVQNHIKSVNWVTRVDLRDKKVEYING 128
Query: 134 LGAFETDKSVKVLPVEGLEGSVTEDHLLESDRIIVATGSEVTPFPGITIDEERIVSSTGA 193
LG+F D + ++ E ++T + ++A G +P I E ++S
Sbjct: 129 LGSF-VDSHTLLAKLKSGERTIT------AQTFVIAVGGRPR-YPDIPGAVEYGITSDDL 180
Query: 194 LSLKEIPKKLAXXXXXXXXLEMGSVYSRLGSKVTVIEFQPQIGATMDGEVAQTTQKILKK 253
SL P K LE LG + TV+ + + D ++A+ +++
Sbjct: 181 FSLDREPGKTLVVGAGYIGLECAGFLKGLGYEPTVM-VRSIVLRGFDQQMAELVAASMEE 239
Query: 254 QGLDFKLSTKVLSASRNGD-VVDIEVEGAKNGKKESLQADVLLVAVGRRPYVAGLNAEKI 312
+G+ F T LS + D + ++ + + G++ D +L A+GR+ V LN
Sbjct: 240 RGIPFLRKTVPLSVEKQDDGKLLVKYKNVETGEEAEDVYDTVLWAIGRKGLVDDLNLPNA 299
Query: 313 GLEVDKRGRLVIDEQLSTKFPHVKVIGDVTFG-PMLAHKAEEEG-IAAAEYFKVGHGHVN 370
G+ V K ++ +D Q +T ++ +GD+ +G P L A G + A + ++
Sbjct: 300 GVTVQK-DKIPVDSQEATNVANIYAVGDIIYGKPELTPVAVLAGRLLARRLYGGSTQRMD 358
Query: 371 YGNIPAVMYSHPEVAWVGKTEEQ-LKEAGIQ--------YKIGKFPFIANSRAKTNMDTE 421
Y ++ +++ E A VG +EE +K+ G YK +F FI +
Sbjct: 359 YKDVATTVFTPLEYACVGLSEEDAVKQFGADEIEVFHGYYKPTEF-FIPQKSVRYC---- 413
Query: 422 GFVKILIDAESE-RLLGAHIIGPNAGEMIAEAGLALEYGASAEDIARVCHAHPTLSEAF 479
++K + + + R+ G H IGP AGE+I AL+ G + + HPT +E F
Sbjct: 414 -YLKAVAERHGDQRVYGLHYIGPVAGEVIQGFAAALKSGLTINTLINTVGIHPTTAEEF 471
>7296552 [O] KOG4716 Thioredoxin reductase
Length = 516
Score = 114 bits (286), Expect = 3e-25
Identities = 111/481 (23%), Positives = 207/481 (42%), Gaps = 31/481 (6%)
Query: 23 HDLVVIGGGPGGYVAAIKAAQLGYDVAC--------VEKRGRLGGTCLNVGCIPSKALLN 74
+DLVV+GGG G A +AA G V C V + +GGTC+NVGCIP K L++
Sbjct: 33 YDLVVLGGGSAGLACAKEAAGCGARVLCFDYVKPTPVGTKWGIGGTCVNVGCIPKK-LMH 91
Query: 75 NSHLYHQMKTDAKQRGIDING-EININVAQFQKAKDTVVKQLTGGIEMLFKKNGVTYYKG 133
+ L + +A G +++ I + + ++ +K + + + V Y
Sbjct: 92 QASLLGEAVHEAVAYGWNVDDTNIRPDWRKLVRSVQNHIKSVNWVTRVDLRDKKVEYVNS 151
Query: 134 LGAFETDKSVKVLPVEGLEGSVTEDHLLESDRIIVATGSEVTPFPGITIDEERIVSSTGA 193
+ F +++ + + G E + S+ ++VA G +P I E ++S
Sbjct: 152 MATFRDSHTIEYVAMPG-----AEHRQVTSEYVVVAVGGRPR-YPDIPGAVELGITSDDI 205
Query: 194 LSLKEIPKKLAXXXXXXXXLEMGSVYSRLGSKVTVIEFQPQIGATMDGEVAQTTQKILKK 253
S + P + LE LG + TV+ + + D ++++ ++ +
Sbjct: 206 FSYEREPGRTLVVGAGYVGLECACFLKGLGYEPTVM-VRSIVLRGFDRQMSELLAAMMTE 264
Query: 254 QGLDFKLSTKVLSASRNGDV-VDIEVEGAKNGKKESLQADVLLVAVGRRPYVAGLNAEKI 312
+G+ F +T + R D + + S D +L A+GR+ + LN +
Sbjct: 265 RGIPFLGTTIPKAVERQADGRLLVRYRNTTTQMDGSDVFDTVLWAIGRKGLIEDLNLDAA 324
Query: 313 GLEVDKRGRLVIDEQLSTKFPHVKVIGDVTFG-PMLAHKAEEEG-IAAAEYFKVGHGHVN 370
G++ ++V+D +T PH+ +GD+ +G P L A G + A F ++
Sbjct: 325 GVKTHD-DKIVVDAAEATSVPHIFAVGDIIYGRPELTPVAILSGRLLARRLFAGSTQLMD 383
Query: 371 YGNIPAVMYSHPEVAWVGKTEEQLKEAGIQYKIGKF-------PFIANSRAKTNMDTEGF 423
Y ++ +++ E + VG +EE E I F F ++ + +
Sbjct: 384 YADVATTVFTPLEYSCVGMSEETAIELRGADNIEVFHGYYKPTEFFIPQKSVRHCYLKAV 443
Query: 424 VKILIDAESERLLGAHIIGPNAGEMIAEAGLALEYGASAEDIARVCHAHPTLSEAFKEAN 483
++ D +++LG H IGP AGE+I AL+ G + + + HPT +E F +
Sbjct: 444 AEVSGD---QKILGLHYIGPVAGEVIQGFAAALKTGLTVKTLLNTVGIHPTTAEEFTRLS 500
Query: 484 L 484
+
Sbjct: 501 I 501
>CE15373 [O] KOG4716 Thioredoxin reductase
Length = 503
Score = 113 bits (283), Expect = 6e-25
Identities = 126/490 (25%), Positives = 206/490 (41%), Gaps = 44/490 (8%)
Query: 20 TKKHDLVVIGGGPGGYVAAIKAAQLGYDVACVEK--------RGRLGGTCLNVGCIPSKA 71
+ K DL+VIG G GG + +AA LG +VA ++ +GGTC NVGCIP K
Sbjct: 18 SNKFDLIVIGAGSGGLSCSKRAADLGANVALIDAVEPTPHGHSWGIGGTCANVGCIPKKL 77
Query: 72 LLNNSHLYHQMKTDAKQ--RGID---INGEINI---NVAQFQKAKDTVVKQLTGGIEMLF 123
+ + + ++K K GID I + N+ NV KA + + + +++
Sbjct: 78 MHQAAIVGKELKHADKYGWNGIDQEKIKHDWNVLSKNVNDRVKANNWIYR-----VQLNQ 132
Query: 124 KKNGVTYYKGLGAF-ETDKSVKVLPVEGLEGSVTEDHLLESDRIIVATGSEVTPFPGITI 182
KK + Y+ F + DK V + G + + T++ L + ++++TG +P I
Sbjct: 133 KK--INYFNAYAEFVDKDKIV----ITGTDKNKTKN-FLSAPNVVISTGLR-PKYPNIP- 183
Query: 183 DEERIVSSTGALSLKEIPKKLAXXXXXXXXLEMGSVYSRLGSKVTVIEFQPQIGATMDGE 242
E ++S +L +P K LE S V V+ + D +
Sbjct: 184 GAELGITSDDLFTLASVPGKTLIVGGGYVALECAGFLSAFNQNVEVLVRSIPLKG-FDRD 242
Query: 243 VAQTTQKILKKQGLDFKLSTKVLSASRNGDVVDIEVEGAKNGKKESLQADVLLVAVGRRP 302
+ LK G+ K +V G + G NG E + D ++ A GR P
Sbjct: 243 CVHFVMEHLKTTGVKVKEHVEVERVEAVGSKKKVTFTG--NGGVE--EYDTVIWAAGRVP 298
Query: 303 YVAGLNAEKIGLEVDKR-GRLVIDEQLSTKFPHVKVIGDVTFGPM-LAHKAEEEG-IAAA 359
+ LN + G+ DKR G+++ DE V +GD+ L A + G + A
Sbjct: 299 NLKSLNLDNAGVRTDKRSGKILADEFDRASCNGVYAVGDIVQDRQELTPLAIQSGKLLAD 358
Query: 360 EYFKVGHGHVNYGNIPAVMYSHPEVAWVGKTEEQLKEAGIQYKIGKFP--FIANSRAKTN 417
F V + + +++ E++ VG TEE+ + + I F F
Sbjct: 359 RLFSNSKQIVRFDGVATTVFTPLELSTVGLTEEEAIQKHGEDSIEVFHSHFTPFEYVVPQ 418
Query: 418 MDTEGFV---KILIDAESERLLGAHIIGPNAGEMIAEAGLALEYGASAEDIARVCHAHPT 474
GF + ES+++LG H +GPNA E+I +A G S D+ HP
Sbjct: 419 NKDSGFCYVKAVCTRDESQKILGLHFVGPNAAEVIQGYAVAFRVGISMSDLQNTIAIHPC 478
Query: 475 LSEAFKEANL 484
SE F + ++
Sbjct: 479 SSEEFVKLHI 488
>Hs22035668 [O] KOG4716 Thioredoxin reductase
Length = 428
Score = 95.9 bits (237), Expect = 1e-19
Identities = 101/407 (24%), Positives = 168/407 (40%), Gaps = 27/407 (6%)
Query: 85 DAKQRGIDINGEININVAQFQKAKDTVVKQLTGGIEMLFKKNGVTYYKGLGAFETDKSVK 144
DA G ++ + + + +A VK L G + + V Y+ +F + +V
Sbjct: 13 DAPNYGWEVAQPVPHDWRKMAEAVQNHVKSLNWGHRVQLQDRKVKYFNIKASFVDEHTVC 72
Query: 145 VLPVEGLEGSVTEDHLLESDRIIVATGSEVTPFPGITIDEERIVSSTGALSLKEIPKKLA 204
+ G E LL +D II+ATG I E ++S LKE P K
Sbjct: 73 GVAKGGKE------ILLSADHIIIATGGRPRYPTHIEGALEYGITSDDIFWLKESPGKTL 126
Query: 205 XXXXXXXXLEMGSVYSRLGSKVTVIEFQPQIGATMDGEVAQTTQKILKKQGLDFKLSTKV 264
LE + +G T++ + D +++ + + G F
Sbjct: 127 VVGASYVALECAGFLTGIGLDTTIMMRSIPLRG-FDQQMSSMVIEHMASHGTRFLRGCAP 185
Query: 265 LSASRNGD-VVDIEVEGAKNGKKESLQADVLLVAVGRRPYVAGLNAEKIGLEVDK-RGRL 322
R D + + E + GK+++ D +L A+GR P LN EK G++ ++
Sbjct: 186 SRVRRLPDGQLQVTWEDSTTGKEDTGTFDTVLWAIGRVPDTRSLNLEKAGVDTSPDTQKI 245
Query: 323 VIDEQLSTKFPHVKVIGDVTFG-PMLAHKAEEEG-IAAAEYFKVGHGHVNYGNIPAVMYS 380
++D + +T PH+ IGDV G P L A G + F ++Y N+P +++
Sbjct: 246 LVDSREATSVPHIYAIGDVVEGRPELTPIAIMAGRLLVQRLFGGSSDLMDYDNVPTTVFT 305
Query: 381 HPEVAWVGKTEEQ---------LKEAGIQYKIGKFPFIANSRAKTNMDTEGFVKILIDAE 431
E VG +EE+ ++ YK +F ++ +VK++ E
Sbjct: 306 PLEYGCVGLSEEEAVARHGQEHVEVYHAHYKPLEFTVAGRDASQC------YVKMVCLRE 359
Query: 432 SERL-LGAHIIGPNAGEMIAEAGLALEYGASAEDIARVCHAHPTLSE 477
+L LG H +GPNAGE+ L ++ GAS + R HPT SE
Sbjct: 360 PPQLVLGLHFLGPNAGEVTQGFALGIKCGASYAQVMRTVGIHPTCSE 406
>CE27373 [R] KOG1336 Monodehydroascorbate/ferredoxin reductase
Length = 549
Score = 60.8 bits (146), Expect = 4e-09
Identities = 55/239 (23%), Positives = 104/239 (43%), Gaps = 10/239 (4%)
Query: 113 KQLTGGIEMLFKKNGVTYYKGLGAFETDKSVKVLPVEGLEGSVTEDHLLESDRIIVATGS 172
K G ++ +K+ Y + F SV + + E S++ + ++I+ATG
Sbjct: 190 KPAATGEDIRLRKDDAFYEERNVKFLLKTSVIAVNHKSREVSLSNGETVVYSKLIIATGG 249
Query: 173 EVTPF--PGITIDEE---RIVSSTGALSLKEIPKKLAXXXXXXXXLEMGSVYSRLGSKVT 227
V PG + R V +S K + +E+ S + + VT
Sbjct: 250 NVRKLQVPGSDLKNICYLRKVEEANIISNLHPGKHVVCVGSSFIGMEVASALAEKAASVT 309
Query: 228 VIEFQPQIGATMDGEVAQTTQKILKKQGLDFKLSTKVLSASRNGDVVDIEVEGAKNGKKE 287
VI P+ ++ + + +++G+ F+L+ V+ A R D ++ +NGK+
Sbjct: 310 VISNTPEPLPVFGSDIGKGIRLKFEEKGVKFELAANVV-ALRGNDQGEVSKVILENGKE- 367
Query: 288 SLQADVLLVAVGRRPYVAGLNAEKIGLEVDKRGRLVIDEQLSTKFPHVKVIGDVTFGPM 346
L D+L+ +G P L E G+++D RG + +DE+ T ++ +GDV P+
Sbjct: 368 -LDVDLLVCGIGVTPATKFL--EGSGIKLDNRGFIEVDEKFRTNISYIFAMGDVVTAPL 423
>YMR145c [C] KOG2495 NADH-dehydrogenase (ubiquinone)
Length = 560
Score = 50.1 bits (118), Expect = 8e-06
Identities = 58/201 (28%), Positives = 88/201 (42%), Gaps = 19/201 (9%)
Query: 225 KVTVIEFQPQIGATMDGEVAQTTQKILKKQGLDFKLSTKVLSASRNGDVVDIEVEGAKNG 284
KVT++E P I D + Q + K++ +D +L T V + D I + +G
Sbjct: 313 KVTLVEALPNILNMFDKYLVDYAQDLFKEEKIDLRLKTMV----KKVDATTITAK-TGDG 367
Query: 285 KKESLQADVLLVAVGRRPYVAGLNAEKIGLEVDKRGRLVIDE--QLSTKFPHVKVIGDVT 342
E++ VL+ A G P N E D R L+ID QL + IGD T
Sbjct: 368 DIENIPYGVLVWATGNAPREVSKNLMTKLEEQDSRRGLLIDNKLQLLGAKGSIFAIGDCT 427
Query: 343 FGPML---AHKAEEEGIAAAEYFKVGH--GHVNYGNIPAVMYSHPEVA----WVGKTEEQ 393
F P L A A +EG A+YFK + +N+ A EVA + KT+ Q
Sbjct: 428 FHPGLFPTAQVAHQEGEYLAQYFKKAYKIDQLNWKMTHA--KDDSEVARLKNQIVKTQSQ 485
Query: 394 LKEAGIQYKIGKFPFIANSRA 414
+++ +K G +I + +A
Sbjct: 486 IEDFKYNHK-GALAYIGSDKA 505
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.315 0.135 0.375
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,937,356
Number of Sequences: 60738
Number of extensions: 1120670
Number of successful extensions: 3080
Number of sequences better than 1.0e-05: 27
Number of HSP's better than 0.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 17
Number of HSP's that attempted gapping in prelim test: 2949
Number of HSP's gapped (non-prelim): 32
length of query: 493
length of database: 30,389,216
effective HSP length: 110
effective length of query: 383
effective length of database: 23,708,036
effective search space: 9080177788
effective search space used: 9080177788
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.5 bits)