ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIV2813 good I KOG2468 Lipid transport and metabolism Dolichol kinase
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIV2813 955786 954242 -515
(515 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YMR013c [I] KOG2468 Dolichol kinase 229 1e-59
SPCC63.10c [I] KOG2468 Dolichol kinase 90 7e-18
Hs7662482 [I] KOG2468 Dolichol kinase 77 6e-14
>YMR013c [I] KOG2468 Dolichol kinase
Length = 519
Score = 229 bits (583), Expect = 1e-59
Identities = 136/411 (33%), Positives = 216/411 (52%), Gaps = 15/411 (3%)
Query: 105 GVNTLPTFNTIYLFYMQLLLSTLFVPQYLLLNTVLAFSISDI----SVFFKIPLQIIFLL 160
G +LP F+TIY Y+ ++S LF ++NT+L S+ + + I LQ+ +
Sbjct: 110 GYKSLPKFDTIYSLYLPFMVSLLFDTSSTVINTILILSVLNSYRWRTQLVVIILQLCLIF 169
Query: 161 MGDDGSANIANDVKALVLNYFFIFGLYKTSKLKSLDKTECHMFALLCTDILALVESDSIY 220
+ + N + ++V+N L +LKSLD + ++F++L T+IL + E+ +++
Sbjct: 170 FNFEAGDRLKNII-SIVINSLLSLILKYIGQLKSLDNIDSNLFSILLTNILYVSEAGTVH 228
Query: 221 FQVFQVCFTSFIVLVTVTSAVSYGLESVGATRWIRTLLLLPMIVVGFSYYIQTNLIINNV 280
F++ + I+ +T +++Y L+ V + +L +G + T + + +
Sbjct: 229 FRILK----GIILALTTIISINYVLKKV---MHFKPFMLSISFAIGLPLFANTFIHLEDG 281
Query: 281 P-PFTWLIDYIGSSMIRLKIMGIWLGSALLLLPSVFALKSNWSLNTSRKVWHFAILPLLI 339
P WL+ YI S IR KI+ W +L +PS+ K + SLNTSRK+WHF I L+I
Sbjct: 282 ENPLLWLVKYILESTIRQKILFAWSSILILSIPSILIEKDSLSLNTSRKLWHFIIFLLII 341
Query: 340 PAIMMDSNFVKIALAGTVNLFLIVEYIRFLHIYPVGHYLDKHLRSFADFRDEKGPXXXXX 399
P+ MDSNFVKIAL+GT+ +FL +EYIRF ++ P+G ++ LR FAD RD GP
Sbjct: 342 PSFQMDSNFVKIALSGTIPVFLSIEYIRFQNLPPLGSAIELQLRRFADDRDHSGPLIISY 401
Query: 400 XXXXXXXXXPFXXXXXXXXXXXXXXXXXXASIIGKKFGRNRWPNTCKTFEXXXXXXXXXX 459
P ASIIGK++GR RW T KT E
Sbjct: 402 LYLLFGISTPLLMNNSPMGLIGLGIGDSLASIIGKRYGRIRWKGTQKTLEGTLAFIVTSF 461
Query: 460 XXXVIMKVYFN--FFTEVSFMNLVLVCFLAGILEGNSTLNDNLLIPTFMLI 508
+++ + F ++ + L+ +C L+G+LEGNS LNDN+LIP FM+I
Sbjct: 462 IVCLVLLRFDKAAIFNHLTTLQLLTLCTLSGVLEGNSVLNDNILIPAFMMI 512
>SPCC63.10c [I] KOG2468 Dolichol kinase
Length = 465
Score = 90.1 bits (222), Expect = 7e-18
Identities = 71/261 (27%), Positives = 112/261 (42%), Gaps = 35/261 (13%)
Query: 282 PFTWLIDYIGS---SMIRLKIMGIW---LGSALLLLPSVFALKSNWS------------- 322
P WL + I S S+ R+KI+ W LG + +L L+SN +
Sbjct: 210 PEVWLFNQIFSHRNSLTRIKIIIWWIICLGCFIFIL-----LRSNRNNPLGKYFTTEDEV 264
Query: 323 LNTSRKVWHFAILPLLIPAIMMDSNFVKIALAGTVNLFLIVEYIRFLHIYPVGHYLDKHL 382
LN RK +H ++ L +P +D +F+ ++ +G + +FL VE IR L + P G + + L
Sbjct: 265 LNFRRKTYHALVVFLFLPVCCLDPHFLHLSFSGVLFIFLFVEGIRILRLKPFGKMIHEFL 324
Query: 383 RSFADFRDEKGPXXXXXXXXXXXXXXPFXXXXXXXXXXXXXX----------XXXXASII 432
+ D RD KGP P ASII
Sbjct: 325 WEYTDNRDHKGPLIISHIYLLIGCAIPIWLSNALKGPVASVELLVGVLCLGCGDSMASII 384
Query: 433 GKKFGRNRWPNTCKTFEXXXXXXXXXXXXXVIMKVYFNFFTEVSFMNLVLVCFLAGILEG 492
GK+FG++R T K+ E + + F+ V+F + + ILEG
Sbjct: 385 GKRFGKHRISKTNKSIEGVFAFSISVFLVLHLTQA-FHVCPSVTFWKTLFMSLCTAILEG 443
Query: 493 NSTLNDNLLIPTFMLILLESM 513
ST NDNL++P +M +L +++
Sbjct: 444 VSTENDNLILPMYMWVLYQAL 464
>Hs7662482 [I] KOG2468 Dolichol kinase
Length = 538
Score = 77.0 bits (188), Expect = 6e-14
Identities = 62/257 (24%), Positives = 97/257 (37%), Gaps = 31/257 (12%)
Query: 282 PFTWLIDYIGSSMIRLKIMGIWLGSALLLLPSVFALKSNWSLNTS-----------RKVW 330
P WL+ ++ + R+ ++ W S L L + L N ++S RK +
Sbjct: 283 PLLWLLQFLFQTDTRIYLLAYW--SLLATLACLVVLYQNAKRSSSESKKHQAPTIARKYF 340
Query: 331 HFAILPLLIPAIMMDSNFVKIALAGTVNLFLIVEYIRFLHIYPVGHYLDKHLRSFADFRD 390
H ++ IP I+ D + +A + +F+ +EY+R+ I P+GH L L F D RD
Sbjct: 341 HLIVVATYIPGIIFDRPLLYVAATVCLAVFIFLEYVRYFRIKPLGHTLRSFLSLFLDERD 400
Query: 391 EKGPXXXXXXXXXXXXXXPF----------------XXXXXXXXXXXXXXXXXXASIIGK 434
GP P ASI G
Sbjct: 401 -SGPLILTHIYLLLGMSLPIWLIPRPCTQKGSLGGARALVPYAGVLAVGVGDTVASIFGS 459
Query: 435 KFGRNRWPNTCKTFEXXXXXXXXXXXXXVIMKVY-FNFFTEVSFMNLVLVCFLAGILEGN 493
G RWP T KTFE ++ ++ S+ ++ +LE
Sbjct: 460 TMGEIRWPGTKKTFEGTMTSIFAQIISVALILIFDSGVDLNYSYAWILGSISTVSLLEAY 519
Query: 494 STLNDNLLIPTFMLILL 510
+T DNLL+P ++LILL
Sbjct: 520 TTQIDNLLLPLYLLILL 536
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.327 0.141 0.420
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,051,176
Number of Sequences: 60738
Number of extensions: 917971
Number of successful extensions: 2795
Number of sequences better than 1.0e-05: 3
Number of HSP's better than 0.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 1
Number of HSP's that attempted gapping in prelim test: 2785
Number of HSP's gapped (non-prelim): 4
length of query: 515
length of database: 30,389,216
effective HSP length: 111
effective length of query: 404
effective length of database: 23,647,298
effective search space: 9553508392
effective search space used: 9553508392
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)