ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIV2847 good R KOG1516 General function prediction only Carboxylesterase and related proteins
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIV2847 968806 967172 -545
(545 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
SPCC417.12 [R] KOG1516 Carboxylesterase and related proteins 432 e-121
CE07374 [R] KOG1516 Carboxylesterase and related proteins 118 2e-26
CE07697 [R] KOG1516 Carboxylesterase and related proteins 100 4e-21
CE09211 [R] KOG1516 Carboxylesterase and related proteins 100 1e-20
CE07375 [R] KOG1516 Carboxylesterase and related proteins 98 3e-20
CE29234 [R] KOG1516 Carboxylesterase and related proteins 97 6e-20
7297536 [R] KOG1516 Carboxylesterase and related proteins 97 6e-20
CE09375 [R] KOG1516 Carboxylesterase and related proteins 97 8e-20
CE07691 [R] KOG1516 Carboxylesterase and related proteins 97 8e-20
CE29530 [R] KOG1516 Carboxylesterase and related proteins 95 2e-19
CE29233 [R] KOG1516 Carboxylesterase and related proteins 94 7e-19
CE04659 [R] KOG1516 Carboxylesterase and related proteins 93 9e-19
Hs7710112 [T] KOG4389 Acetylcholinesterase/Butyrylcholinesterase 91 6e-18
Hs4557239 [T] KOG4389 Acetylcholinesterase/Butyrylcholinesterase 91 6e-18
CE17905 [R] KOG1516 Carboxylesterase and related proteins 91 6e-18
7291308 [R] KOG1516 Carboxylesterase and related proteins 90 8e-18
7302992 [R] KOG1516 Carboxylesterase and related proteins 89 2e-17
CE07347 [R] KOG1516 Carboxylesterase and related proteins 87 6e-17
7297440 [R] KOG1516 Carboxylesterase and related proteins 87 6e-17
Hs7662470 [R] KOG1516 Carboxylesterase and related proteins 85 2e-16
Hs4502771_1 [R] KOG1516 Carboxylesterase and related proteins 85 3e-16
CE28131 [T] KOG4389 Acetylcholinesterase/Butyrylcholinesterase 84 4e-16
7291738 [R] KOG1516 Carboxylesterase and related proteins 84 5e-16
7294607 [R] KOG1516 Carboxylesterase and related proteins 84 7e-16
Hs4557351 [T] KOG4389 Acetylcholinesterase/Butyrylcholinesterase 82 3e-15
7302991 [R] KOG1516 Carboxylesterase and related proteins 82 3e-15
7299402 [R] KOG1516 Carboxylesterase and related proteins 80 8e-15
7298797 [R] KOG1516 Carboxylesterase and related proteins 80 1e-14
Hs20554181 [R] KOG1516 Carboxylesterase and related proteins 79 2e-14
7298803 [R] KOG1516 Carboxylesterase and related proteins 79 2e-14
CE09376 [R] KOG1516 Carboxylesterase and related proteins 78 3e-14
7290457 [R] KOG1516 Carboxylesterase and related proteins 78 3e-14
7299734 [T] KOG4389 Acetylcholinesterase/Butyrylcholinesterase 77 7e-14
CE26734 [T] KOG4389 Acetylcholinesterase/Butyrylcholinesterase 77 9e-14
CE14345 [R] KOG1516 Carboxylesterase and related proteins 77 9e-14
CE14343 [R] KOG1516 Carboxylesterase and related proteins 77 9e-14
7297537 [R] KOG1516 Carboxylesterase and related proteins 77 9e-14
7298250 [R] KOG1516 Carboxylesterase and related proteins 76 1e-13
7296094 [R] KOG1516 Carboxylesterase and related proteins 76 1e-13
CE28655 [R] KOG1516 Carboxylesterase and related proteins 76 1e-13
CE07569 [T] KOG4389 Acetylcholinesterase/Butyrylcholinesterase 75 3e-13
7298801 [R] KOG1516 Carboxylesterase and related proteins 75 3e-13
7301005 [R] KOG1516 Carboxylesterase and related proteins 73 1e-12
CE28763 [R] KOG1516 Carboxylesterase and related proteins 73 1e-12
7300594 [R] KOG1516 Carboxylesterase and related proteins 72 2e-12
CE15485 [R] KOG1516 Carboxylesterase and related proteins 72 3e-12
CE28363 [T] KOG4389 Acetylcholinesterase/Butyrylcholinesterase 70 8e-12
Hs9506787 [R] KOG1516 Carboxylesterase and related proteins 69 2e-11
Hs4504565 [R] KOG1516 Carboxylesterase and related proteins 68 3e-11
CE13028 [R] KOG1516 Carboxylesterase and related proteins 68 3e-11
7298793 [R] KOG1516 Carboxylesterase and related proteins 68 3e-11
CE22953 [R] KOG1516 Carboxylesterase and related proteins 68 4e-11
CE09404 [R] KOG1516 Carboxylesterase and related proteins 68 4e-11
7296447 [R] KOG1516 Carboxylesterase and related proteins 67 5e-11
Hs6912298 [R] KOG1516 Carboxylesterase and related proteins 67 9e-11
CE17255 [R] KOG1516 Carboxylesterase and related proteins 67 9e-11
CE29456 [R] KOG1516 Carboxylesterase and related proteins 65 2e-10
7294606 [R] KOG1516 Carboxylesterase and related proteins 64 4e-10
7291429 [R] KOG1516 Carboxylesterase and related proteins 64 4e-10
7298805 [R] KOG1516 Carboxylesterase and related proteins 64 6e-10
Hs21450749 [R] KOG1516 Carboxylesterase and related proteins 63 1e-09
CE15197 [R] KOG1516 Carboxylesterase and related proteins 63 1e-09
Hs16905524 [R] KOG1516 Carboxylesterase and related proteins 62 2e-09
CE15193 [R] KOG1516 Carboxylesterase and related proteins 62 3e-09
7298795 [R] KOG1516 Carboxylesterase and related proteins 62 3e-09
CE26855 [R] KOG1516 Carboxylesterase and related proteins 61 4e-09
CE16865 [R] KOG1516 Carboxylesterase and related proteins 61 5e-09
CE09114 [R] KOG1516 Carboxylesterase and related proteins 61 5e-09
CE18745 [R] KOG1516 Carboxylesterase and related proteins 60 6e-09
7298794 [R] KOG1516 Carboxylesterase and related proteins 60 8e-09
CE27775 [R] KOG1516 Carboxylesterase and related proteins 59 1e-08
7303171 [R] KOG1516 Carboxylesterase and related proteins 59 1e-08
CE15195 [R] KOG1516 Carboxylesterase and related proteins 59 2e-08
CE06735 [R] KOG1516 Carboxylesterase and related proteins 59 2e-08
7298800 [R] KOG1516 Carboxylesterase and related proteins 59 2e-08
Hs7706475 [R] KOG1516 Carboxylesterase and related proteins 58 3e-08
CE23015 [R] KOG1516 Carboxylesterase and related proteins 57 5e-08
CE18546 [R] KOG1516 Carboxylesterase and related proteins 57 9e-08
CE26673 [R] KOG1516 Carboxylesterase and related proteins 56 1e-07
7298806 [R] KOG1516 Carboxylesterase and related proteins 56 2e-07
CE07376 [R] KOG1516 Carboxylesterase and related proteins 55 3e-07
7298796 [R] KOG1516 Carboxylesterase and related proteins 55 3e-07
Hs7662400 [R] KOG1516 Carboxylesterase and related proteins 54 5e-07
7297441 [R] KOG1516 Carboxylesterase and related proteins 54 8e-07
7297439 [R] KOG1516 Carboxylesterase and related proteins 54 8e-07
CE08329 [R] KOG1516 Carboxylesterase and related proteins 53 1e-06
CE14347 [R] KOG1516 Carboxylesterase and related proteins 52 2e-06
Hs18594215 [R] KOG1516 Carboxylesterase and related proteins 50 9e-06
7298791 [R] KOG1516 Carboxylesterase and related proteins 50 9e-06
7297184 [R] KOG1516 Carboxylesterase and related proteins 50 9e-06
>SPCC417.12 [R] KOG1516 Carboxylesterase and related proteins
Length = 520
Score = 432 bits (1111), Expect = e-121
Identities = 229/511 (44%), Positives = 316/511 (61%), Gaps = 30/511 (5%)
Query: 39 HRFAQIPYAEPFTKENRFKRPVPLADDFDYTGDYKEFGLKCPQP-------SVPNPAFRY 91
HRF I YA+P + R++RPV L D +DY+GDY +F CPQP V NP F+Y
Sbjct: 19 HRFTGIRYAKPPVGKLRWRRPVTLEDGYDYSGDYNQFKTICPQPFYNNRKNQVRNPDFKY 78
Query: 92 TKSPSDENINKLNIWVPSSDKYKESDGWPVLVYIHGGWLQYSSPYSEFFNTNEMFDDEEF 151
DE+ LNIWVP+ +K ++GWPVL +IHGGWLQ +P + +
Sbjct: 79 -----DEDCLFLNIWVPAGEK--PAEGWPVLYFIHGGWLQVGNPLHYRQCDPQDLQADGS 131
Query: 152 TQKYILVTPGYRLNMFGFLSGKELLEEDEASSNFGFWDQRLAIEWTYKYIKYFGGNPDKI 211
K+ILV+PG+RLN+FGFL+GKELLEED SSNFGFWDQRL +EWTYK+I+ FGGN + I
Sbjct: 132 PAKFILVSPGHRLNLFGFLAGKELLEEDPKSSNFGFWDQRLGLEWTYKHIESFGGNKENI 191
Query: 212 SVGGISAGAYSTFFQLAYELYHPEDNQIIKQALFFSNLVYVQPKTIEECQEQFDEIVEKL 271
+VGGISAG+YS FQL YE YHPE NQIIK+AL SN + VQPK++EE Q QF+E+ +K
Sbjct: 192 AVGGISAGSYSALFQLIYETYHPEANQIIKRALLLSNGLSVQPKSVEESQIQFNELAQKF 251
Query: 272 DIDPKASGQEKLAVLRELDAPFIEDFIPTLTHHTFRAVTDDKFISSTLIKDLDSGEYARR 331
I + S EKL LR + + D I L HTFRAVTD F++ KD+ G + +R
Sbjct: 252 GIPLELSSAEKLEKLRAIPFQDLADNILNLRLHTFRAVTDGDFVNPNTFKDIYDGTFGKR 311
Query: 332 LLSIKGDKFRILCGEVDNEPLKYSLLNTPQTLGELPVQVGNYYPKNIVDSLLDLYKVDKL 391
I+ ++ GEV+NE Y+ N P++ +L QV NYYP+ + +LL+LY
Sbjct: 312 ---IRDSGRELIIGEVNNEHSIYANTNPPKSKEDLFNQVNNYYPEKVTKALLELY----- 363
Query: 392 NPASPTLKED------LRVAYGDIIGDGQVYASGRGYLHKLVEHGFPSKNIFRYRVSYRA 445
P P ++++ ++ +G I+ D QVYAS R ++ LV+ G P + I+RYR+++R
Sbjct: 364 -PKVPDMEDEKEYLAAIKALFGSIVSDMQVYASTRVLINGLVKGGVPLEKIYRYRIAFRG 422
Query: 446 KWLDNHIEPDDRVPHAGDFSLWFYCLREGYTDEERIHINEWLQPYLQFLNFKSLDSWDSD 505
K+ D + P+ VPHAGD LWFY + +G EE WL+ Y ++++ D W +
Sbjct: 423 KFFDKYEPPESLVPHAGDLGLWFYNVVDGILPEEIPIYKAWLKSYGEWMSTGKTD-WGTT 481
Query: 506 DVKKYRIFKEDGSFDYVDDIHWDWGVKVATT 536
++YR+ DG+ VDD WDWG+KV T
Sbjct: 482 KTEEYRLLDADGTIKVVDDEKWDWGLKVGRT 512
>CE07374 [R] KOG1516 Carboxylesterase and related proteins
Length = 565
Score = 118 bits (296), Expect = 2e-26
Identities = 115/428 (26%), Positives = 191/428 (43%), Gaps = 53/428 (12%)
Query: 32 RTNNVTTHRFAQIPYAEPFTKENRFKRPVPLADDFDYTGDYKEFGLKCPQPS--VPNPAF 89
R + H + +PYA+P T E RF +PVP ADD+ T D ++G +CP + F
Sbjct: 30 RHGDKEVHGYLGMPYAKPPTGEMRFAKPVP-ADDWTETRDCTKYGPRCPPSGQGLEKGMF 88
Query: 90 RYTKSPSDENINKLNIWVPSSDKYKESDGWPVLVYIHGGWLQYSSPYSEFFNTNEMFDDE 149
P + N +N++VP + + + PV+VY+HGG + SS EF + +
Sbjct: 89 VNPDEPDEANGLSVNVFVPGWESSEYKNARPVMVYVHGGGFEISSS-REFCDYS--ISST 145
Query: 150 EFTQKYILVTPGYRLNMFGFLSGKELLEEDEASSNFGFWDQRLAIEWTYKYIKYFGGNPD 209
+ ILVT YRL + GF + ++ NFG WDQ LA++W K+I FGG+P+
Sbjct: 146 LPMKDVILVTMNYRLGILGFFT----TGDEVCPGNFGLWDQTLALQWVQKHIASFGGDPN 201
Query: 210 KISVGGISA-GAYSTFFQLAYELYHPEDNQIIKQALFFSNLVYVQ--------------- 253
+++ G SA GA L+ P I + N +Y+
Sbjct: 202 NVTLFGQSAGGACVDLLTLS-----PHSRGDITIEIMIKNYIYLDLFQKVVPMSGSAMCE 256
Query: 254 --PKTIEECQEQFDEIVEKLDIDPKASGQEKLAVLRELDAPFIEDFIPTLTHHTFRAVTD 311
+T E FD+I+ +L S +E+L +R L D I T +T++
Sbjct: 257 FAMRTAENEAHVFDDILARLGFTGSGS-KERLEFMRSLPC----DKITGKTGYTYK---Q 308
Query: 312 DKFISSTLIKDLDSGEYARRLLSIKGD--KFRILCGEVDNEPLKYSL-LNTP--QTLGEL 366
F+S L + D + + L ++ D K ++ G V NE L ++ NTP L
Sbjct: 309 SGFMS--LCPNYDGDFFPKPLDELRKDASKRILMTGIVGNEGLLFAFDRNTPYKDYTDLL 366
Query: 367 PVQVGNYYPKNIVDSL----LDLYKVDKLNPASPTLKEDLRVAYGDIIGDGQVYASGRGY 422
+++ Y +++VD + ++++ N + + +R A + +GD + R
Sbjct: 367 RLKIEEDYKEDVVDDVEGIRKEIFEYYTKNISEGDEEAIMRKA-AEFVGDSIFHTGVRAT 425
Query: 423 LHKLVEHG 430
EHG
Sbjct: 426 AQNAAEHG 433
>CE07697 [R] KOG1516 Carboxylesterase and related proteins
Length = 578
Score = 100 bits (250), Expect = 4e-21
Identities = 76/249 (30%), Positives = 121/249 (48%), Gaps = 30/249 (12%)
Query: 21 GTLTGYTFKSPRTNNVTTHRFAQIPYAEPFTKENRFKRPVPLADDFDYTGDYKEFGLKCP 80
G + G +K + + IP+A+ +FK+PV A+ + D E+G CP
Sbjct: 39 GPIRGNIYKHKNGTKIVDG-YLGIPFAKAPVGALKFKKPVA-AEKWTEPRDCYEYGPGCP 96
Query: 81 QPS-VPNPAFRYTKSPSDENINKLNIWVPSSDKYKESDGWPVLVYIHGGWLQYSSPYSEF 139
Q + T + ++EN LN++ P + G PVLVYI+GG Y ++ +
Sbjct: 97 QTGRFAALTAKSTAAFAEENCLTLNVFAPRWKLAEFPKGLPVLVYIYGGG--YEIGFTSY 154
Query: 140 FNTNEMFDDEEFT-----QKYILVTPGYRLNMFGFLSGKELLEEDEASSNFGFWDQRLAI 194
DD T + I+VT YRL GFL+ + + A+ N+G WDQ LA+
Sbjct: 155 M------DDYSLTGTLPLKDVIVVTMNYRLGPLGFLT----IADGIANGNYGLWDQTLAL 204
Query: 195 EWTYKYIKYFGGNPDKISVGGISAGAYST-FFQLAYELYHPEDNQIIKQALFFSNLVY-- 251
+W I FGGNP+ +++ G SAGA ST F L+ P NQ+ ++++ S +
Sbjct: 205 QWVQDNIASFGGNPESVTLSGTSAGATSTDFLSLS-----PHSNQLFQRSISMSGTAFCN 259
Query: 252 --VQPKTIE 258
++PK +E
Sbjct: 260 FAIRPKDVE 268
>CE09211 [R] KOG1516 Carboxylesterase and related proteins
Length = 564
Score = 99.8 bits (247), Expect = 1e-20
Identities = 61/195 (31%), Positives = 99/195 (50%), Gaps = 14/195 (7%)
Query: 32 RTNNVTTHRFAQIPYAEPFTKENRFKRPVPLADDFDYTGDYKEFGLKCPQPSVPNPAFRY 91
R N+ + IPYA+P E RFK+PVP A + T + ++G +CPQ +
Sbjct: 30 RHNDKIVDGYLGIPYAKPPVGELRFKKPVPAAI-WTETRNCTKYGPRCPQSGAFPEMINF 88
Query: 92 TKS--PSDENINKLNIWVPSSDKYKESDGWPVLVYIHGGWLQYSSP--YSEFFNTNEMFD 147
K P + N LN++ P + + + PV+VY+HGG + S+ Y ++ + +
Sbjct: 89 QKEDIPDEANCLTLNVFAPRWESEEFKNKRPVMVYVHGGGFELSASRDYCDYSVSGTLP- 147
Query: 148 DEEFTQKYILVTPGYRLNMFGFLSGKELLEEDEASSNFGFWDQRLAIEWTYKYIKYFGGN 207
+ ++VT YR+ + GF + + NFG WDQ LA++W ++I FGG+
Sbjct: 148 ----LKDVVVVTLNYRVGILGFFT----TGDSACRGNFGLWDQTLALKWVQRHISSFGGD 199
Query: 208 PDKISVGGISAGAYS 222
P ++V G SAG S
Sbjct: 200 PQNVTVFGQSAGGVS 214
>CE07375 [R] KOG1516 Carboxylesterase and related proteins
Length = 547
Score = 98.2 bits (243), Expect = 3e-20
Identities = 65/197 (32%), Positives = 100/197 (49%), Gaps = 15/197 (7%)
Query: 35 NVTTHRFAQIPYAEPFTKENRFKRPVPLADDFDYTGDYKEFGLKCPQPSV--PNPAFRYT 92
N H + IPYA+P RFK+PV AD + T D ++G +CP + N T
Sbjct: 51 NEEVHGYLGIPYAQPPIGILRFKKPVS-ADVWTETRDCTKYGPRCPPSGMLYENLQLPNT 109
Query: 93 KSPSDENINKLNIWVPSSDKYKESDGWPVLVYIHGGWLQYSSP--YSEFFNTNEMFDDEE 150
P + N LN++ P + K+S PV+++IHGG + S+ Y ++ + +
Sbjct: 110 DIPDEANCLSLNVFCPQWE-IKQSAKHPVMIFIHGGGFELSASKDYCDYSLSGTLP---- 164
Query: 151 FTQKYILVTPGYRLNMFGFLSGKELLEEDEASSNFGFWDQRLAIEWTYKYIKYFGGNPDK 210
+ I+VT YR+ GFL+ +D NFG WD LA++W +I FGG+P
Sbjct: 165 -LKDVIVVTVNYRVGALGFLT----TGDDSCRGNFGLWDLTLALKWVSTHISSFGGDPKN 219
Query: 211 ISVGGISAGAYSTFFQL 227
+++ G SAGA F +L
Sbjct: 220 VTLFGQSAGAVYLFHKL 236
>CE29234 [R] KOG1516 Carboxylesterase and related proteins
Length = 544
Score = 97.1 bits (240), Expect = 6e-20
Identities = 62/190 (32%), Positives = 94/190 (48%), Gaps = 21/190 (11%)
Query: 44 IPYAEPFTKENRFKRPVPLADDFDYTGDYKEFGLKCPQPSVPNPAFRYTKSPSD---ENI 100
IP+A+ + RFK+ V A+ + D ++G CPQ + + D +N
Sbjct: 42 IPFAKAPIGDLRFKKSVE-AEKWTQPLDCYKYGPGCPQSAALGALMVSQATNHDFAEDNC 100
Query: 101 NKLNIWVPSSDKYKESDGWPVLVYIHGGWLQYSSPYSEFFNTNEMFDDEEFT-----QKY 155
LN++ P + +G+PV+VY +GG + + MFDD T +
Sbjct: 101 LNLNVFAPKWKSAEFPNGFPVMVYFYGGGFEVGF--------SSMFDDYSLTGTLPLKDV 152
Query: 156 ILVTPGYRLNMFGFLSGKELLEEDEASSNFGFWDQRLAIEWTYKYIKYFGGNPDKISVGG 215
ILVTP YR+ GF + +D A N+G WDQ LA++W K+IK FGG+P +++ G
Sbjct: 153 ILVTPNYRIGPLGFFA----TGDDVARGNWGLWDQALALQWVQKHIKSFGGDPSNVTISG 208
Query: 216 ISAGAYSTFF 225
SAG S F
Sbjct: 209 TSAGGASVDF 218
>7297536 [R] KOG1516 Carboxylesterase and related proteins
Length = 564
Score = 97.1 bits (240), Expect = 6e-20
Identities = 70/211 (33%), Positives = 100/211 (47%), Gaps = 23/211 (10%)
Query: 21 GTLTGYTFKSPRTNNVTTHRFAQIPYAEPFTKENRFKRPVPLADDFDYTGDYKEFGLKCP 80
G + G T +S N T + F I YA+ + RF PVP D + L CP
Sbjct: 36 GRIQGDTMQS--FGNKTIYAFRGIRYAQSPVGQLRFANPVPETSWGDEVFNATSDSLVCP 93
Query: 81 QPSVPNPAFRYTKSPSDENINKLNIWVPSSDKYKESDGWPVLVYIHGGWLQYSSPYSEFF 140
QP V S E+ K+N++ S + D +PV+VYIHGG S +S +
Sbjct: 94 QPGVV--------SLMSEDCLKINVFTKSFE-----DKFPVMVYIHGGANVLGSGHSSYE 140
Query: 141 NTNEMFDDEEFTQKYILVTPGYRLNMFGFLSGKELLEEDEASSNFGFWDQRLAIEWTYKY 200
+ D++ + V YRL GFLS E NFGF DQ +A+EW +
Sbjct: 141 AGPQYLLDQDV----VFVAFNYRLGALGFLS----TNSSETKGNFGFLDQVMALEWVRDH 192
Query: 201 IKYFGGNPDKISVGGISAGAYSTFFQLAYEL 231
I +FGG+P+ +++ GISAG+ + LA L
Sbjct: 193 ISHFGGDPELVTIIGISAGSMAVSLHLASPL 223
>CE09375 [R] KOG1516 Carboxylesterase and related proteins
Length = 554
Score = 96.7 bits (239), Expect = 8e-20
Identities = 67/206 (32%), Positives = 106/206 (50%), Gaps = 16/206 (7%)
Query: 21 GTLTGYTFKSPRTNNVTTHRFAQIPYAEPFTKENRFKRPVPLADDFDYTGDYKEFGLKCP 80
G + G +K ++V + IPYA+P E RFK+PV + D + D ++G C
Sbjct: 22 GPVRGNIYKH---DDVIVDGYLGIPYAKPPVGELRFKKPVTV-DVWTEIKDCYKYGPACV 77
Query: 81 QPS-VPNPAFRYTKSPSDENINKLNIWVPSSDKYKESDGWPVLVYIHGGWLQY--SSPYS 137
Q A T +P + LN++ P + + +G PV+VYIHGG + SS +
Sbjct: 78 QTGGFEQIAGPRTPTPEEAGCLTLNVFTPRNASSEFKNGRPVMVYIHGGGYELCASSDFC 137
Query: 138 EFFNTNEMFDDEEFTQKYILVTPGYRLNMFGFLSGKELLEEDEASSNFGFWDQRLAIEWT 197
+ + + + ++V+ YRL +FGFL+ ++ NFG WDQ LA++W
Sbjct: 138 AYSLSGTLP-----LKDVVVVSINYRLGVFGFLT----TGDNVCPGNFGLWDQTLALKWV 188
Query: 198 YKYIKYFGGNPDKISVGGISAGAYST 223
K+I FGG+P+ ++V G SAG ST
Sbjct: 189 QKHISSFGGDPNCVTVFGQSAGGAST 214
>CE07691 [R] KOG1516 Carboxylesterase and related proteins
Length = 545
Score = 96.7 bits (239), Expect = 8e-20
Identities = 62/191 (32%), Positives = 94/191 (48%), Gaps = 22/191 (11%)
Query: 44 IPYAEPFTKENRFKRPVPLADDFDYTGDYKEFGLKCPQPSVPN----PAFRYTKSPSDEN 99
IP+A+ E RFK+ V A+ + D ++G CPQ P + +++N
Sbjct: 42 IPFAKAPIGELRFKKSVE-AEKWTEPLDCYKYGPGCPQSGALGAMIVPQASAIREFAEDN 100
Query: 100 INKLNIWVPSSDKYKESDGWPVLVYIHGGWLQYSSPYSEFFNTNEMFDDEEFT-----QK 154
LN++ P + +G PV+VY +GG + + MFDD T +
Sbjct: 101 CLTLNVFAPKWKSAEFPNGLPVIVYFYGGGFEVGF--------SSMFDDYSLTGTLPLKD 152
Query: 155 YILVTPGYRLNMFGFLSGKELLEEDEASSNFGFWDQRLAIEWTYKYIKYFGGNPDKISVG 214
ILVTP YR+ GF + +D + N+G WDQ LA++W K+IK FGG+P +++
Sbjct: 153 VILVTPNYRIGPLGFFA----TGDDVSRGNWGLWDQALALQWVQKHIKSFGGDPSNVTIS 208
Query: 215 GISAGAYSTFF 225
G SAG S F
Sbjct: 209 GTSAGGASVDF 219
>CE29530 [R] KOG1516 Carboxylesterase and related proteins
Length = 811
Score = 95.1 bits (235), Expect = 2e-19
Identities = 61/190 (32%), Positives = 93/190 (48%), Gaps = 21/190 (11%)
Query: 44 IPYAEPFTKENRFKRPVPLADDFDYTGDYKEFGLKCPQPSVPNPAFRYTKSPSD---ENI 100
IP+A+ + RFK+ V A+ + D ++G CPQ + D +N
Sbjct: 368 IPFAKAPIGDLRFKKSVE-AEKWTEPLDCYKYGPGCPQSGALGTMMVSQATNHDFAEDNC 426
Query: 101 NKLNIWVPSSDKYKESDGWPVLVYIHGGWLQYSSPYSEFFNTNEMFDDEEFT-----QKY 155
LN++ P + +G+PV+VY +GG + + MFDD T +
Sbjct: 427 LNLNVFAPKWKSAEFPNGFPVMVYFYGGGFEVGF--------SSMFDDYSLTGTLPLKDV 478
Query: 156 ILVTPGYRLNMFGFLSGKELLEEDEASSNFGFWDQRLAIEWTYKYIKYFGGNPDKISVGG 215
ILVTP YR+ GF + +D + N+G WDQ LA++W K+IK FGG+P +++ G
Sbjct: 479 ILVTPNYRIGPLGFFA----TGDDVSRGNWGLWDQALALQWVQKHIKSFGGDPSNVTISG 534
Query: 216 ISAGAYSTFF 225
SAG S F
Sbjct: 535 TSAGGASVDF 544
Score = 90.9 bits (224), Expect = 4e-18
Identities = 59/183 (32%), Positives = 94/183 (51%), Gaps = 14/183 (7%)
Query: 44 IPYAEPFTKENRFKRPVPLADDFDYTGDYKEFGLKCPQPSVPNPAF--RYTKSPSDENIN 101
IP+A+ E RFK+PV A+ + D ++G CPQ + +++N
Sbjct: 42 IPFAKAPIGELRFKKPVE-AEKWTEPLDCYKYGPGCPQSGYLGATLVPKGYVELNEDNCL 100
Query: 102 KLNIWVPSSDKYKESDGWPVLVYIHGGWLQ--YSSPYSEFFNTNEMFDDEEFTQKYILVT 159
LN++ P + G PV+VY +GG + +SS Y+++ T + + ILVT
Sbjct: 101 TLNVFAPRWKVTELPKGLPVMVYFYGGGFEIGFSSLYNDYSLTGSLP-----LKDVILVT 155
Query: 160 PGYRLNMFGFLSGKELLEEDEASSNFGFWDQRLAIEWTYKYIKYFGGNPDKISVGGISAG 219
YR+ GF + +D A N+G WDQ + ++W K+IK FGG+PD +++ G SAG
Sbjct: 156 SNYRVGPLGFFT----TGDDVARGNYGSWDQTMTLQWVQKHIKSFGGDPDNVTIFGTSAG 211
Query: 220 AYS 222
S
Sbjct: 212 GAS 214
>CE29233 [R] KOG1516 Carboxylesterase and related proteins
Length = 545
Score = 93.6 bits (231), Expect = 7e-19
Identities = 64/199 (32%), Positives = 102/199 (51%), Gaps = 22/199 (11%)
Query: 32 RTNNVTTHRFAQIPYAEPFTKENRFKRPVPLADDFDYTGDYKEFGLKCPQPS--VPNPAF 89
R ++ + + IP+A+ E RFK+PV A+ + + ++G CPQ + N
Sbjct: 30 RHDDKIVNGYLGIPFAKAPICELRFKKPVE-AEKWTKPLNCHKYGPGCPQSGHMISNLLP 88
Query: 90 RYTKSPSDENINKLNIWVPSSDKYKESDGWPVLVYIHGGWLQYSSPYSEFFNTNEMFDDE 149
+ +++N LNI+ PS + +G P++VY HGG + + MFDD
Sbjct: 89 PGYREFAEDNCLNLNIFAPSWKSEEFPNGLPIMVYFHGGGFE--------IGFSSMFDDY 140
Query: 150 EFT-----QKYILVTPGYRLNMFGFLSGKELLEEDEAS-SNFGFWDQRLAIEWTYKYIKY 203
+ + I+VT YR+ GF++ DE S N+G WDQ LA++W ++IK
Sbjct: 141 SLSGTLPLKDVIVVTANYRVGPLGFMT-----TGDEVSRGNYGLWDQTLALKWVQEHIKS 195
Query: 204 FGGNPDKISVGGISAGAYS 222
FGGNP+ ++V G SAG S
Sbjct: 196 FGGNPNIVTVCGTSAGGVS 214
>CE04659 [R] KOG1516 Carboxylesterase and related proteins
Length = 730
Score = 93.2 bits (230), Expect = 9e-19
Identities = 69/202 (34%), Positives = 95/202 (46%), Gaps = 25/202 (12%)
Query: 34 NNVTTHRFAQIPYAEPFTKENRFKRPVPLAD--------DFDYTGDYKEFGLKCPQPSVP 85
NN+T F +PYAEP T + RFK P L F+Y + K P P V
Sbjct: 102 NNITVFTFLGVPYAEPPTSQRRFKPPQQLTVFPGKQPYLAFNYAASCAQDVEKSPSPFVD 161
Query: 86 NPAFRYTKSPSDENINKLNIWVPSSDKYKESDGWPVLVYIHGGWLQYSSPYSEFFNTNEM 145
+P DE+ LNI+ P K ++ +PV+V+ HGG Q S NE
Sbjct: 162 HPY----PFMVDEDCLYLNIFSPDISKNAQTT-YPVIVFFHGGNFQTGS-------ANEW 209
Query: 146 FDDEEFTQKYILVTPGYRLNMFGFLSGKELLEEDEASSNFGFWDQRLAIEWTYKYIKYFG 205
++ ++VT YRL FGF+S D + N+G DQRLA+E+ I FG
Sbjct: 210 PAHGLASRGMVVVTVNYRLGAFGFMS-----MGDSETGNYGLQDQRLALEFVKNNIVTFG 264
Query: 206 GNPDKISVGGISAGAYSTFFQL 227
G+P ++V G AGA S F +
Sbjct: 265 GDPQAVTVVGHDAGAASIGFHM 286
>Hs7710112 [T] KOG4389 Acetylcholinesterase/Butyrylcholinesterase
Length = 617
Score = 90.5 bits (223), Expect = 6e-18
Identities = 123/497 (24%), Positives = 206/497 (40%), Gaps = 52/497 (10%)
Query: 21 GTLTGYTFKSPRTNNVTTHRFAQIPYAEPFTKENRFKRPVPLADDFDYTGDYKEFGLKCP 80
G L G K+P F IP+AEP RF P P + D F C
Sbjct: 46 GRLRGIRLKTP---GGPVSAFLGIPFAEPPMGPRRFLPPEP-KQPWSGVVDATTFQSVCY 101
Query: 81 Q-PSVPNPAFRYTK--SPS---DENINKLNIWVPSSDKYKESDGWPVLVYIHGGWLQYSS 134
Q P F T+ +P+ E+ LN+W P + + PVLV+I+GG +
Sbjct: 102 QYVDTLYPGFEGTEMWNPNRELSEDCLYLNVWTPYP---RPTSPTPVLVWIYGGGFYSGA 158
Query: 135 PYSEFFNTNEMFDDEEFTQKYILVTPGYRLNMFGFLSGKELLEEDEASSNFGFWDQRLAI 194
+ ++ + E + +LV+ YR+ FGFL+ L EA N G DQRLA+
Sbjct: 159 SSLDVYDGRFLVQAE----RTVLVSMNYRVGAFGFLA---LPGSREAPGNVGLLDQRLAL 211
Query: 195 EWTYKYIKYFGGNPDKISVGGISAGAYSTFFQLAYELYHPEDNQIIKQALFFSNLVYVQP 254
+W + + FGG+P +++ G SAGA S + L P + +A+ S
Sbjct: 212 QWVQENVAAFGGDPTSVTLFGESAGAAS----VGMHLLSPPSRGLFHRAVLQSGAPNGPW 267
Query: 255 KTI--EECQEQFDEIVEKLDIDPKASG---QEKLAVLRELDAPFIED----FIP--TLTH 303
T+ E + + ++ + P +G E +A LR A + + +P ++
Sbjct: 268 ATVGMGEARRRATQLAHLVGCPPGGTGGNDTELVACLRTRPAQVLVNHEWHVLPQESVFR 327
Query: 304 HTFRAVTDDKFISSTLIKDLDSGEY--ARRLLSIKGDK--FRILCGEVDNEPLKYSLLNT 359
+F V D F+S T +++G++ + L+ + D+ + ++ G SL++
Sbjct: 328 FSFVPVVDGDFLSDTPEALINAGDFHGLQVLVGVVKDEGSYFLVYGAPGFSKDNESLISR 387
Query: 360 PQTLGELPVQVGNYYPKNIVDSLLDLYKVDKLNPASPTLKEDLRVAYGDIIGDGQVYASG 419
+ L V+VG ++ + L+ D L+P P LR A D++GD V
Sbjct: 388 AEFLA--GVRVGVPQVSDLAAEAVVLHYTDWLHPEDPA---RLREALSDVVGDHNVVCPV 442
Query: 420 RGYLHKLVEHGFPSKNIFRYRVSYRAKWLDNHIEPDDRVPHAGDFSLWFYCLRE---GYT 476
+L G ++ Y +RA L + VPH + F + YT
Sbjct: 443 AQLAGRLAAQG---ARVYAYVFEHRASTLSWPLWMG--VPHGYEIEFIFGIPLDPSRNYT 497
Query: 477 DEERIHINEWLQPYLQF 493
EE+I ++ + F
Sbjct: 498 AEEKIFAQRLMRYWANF 514
>Hs4557239 [T] KOG4389 Acetylcholinesterase/Butyrylcholinesterase
Length = 614
Score = 90.5 bits (223), Expect = 6e-18
Identities = 123/497 (24%), Positives = 206/497 (40%), Gaps = 52/497 (10%)
Query: 21 GTLTGYTFKSPRTNNVTTHRFAQIPYAEPFTKENRFKRPVPLADDFDYTGDYKEFGLKCP 80
G L G K+P F IP+AEP RF P P + D F C
Sbjct: 46 GRLRGIRLKTP---GGPVSAFLGIPFAEPPMGPRRFLPPEP-KQPWSGVVDATTFQSVCY 101
Query: 81 Q-PSVPNPAFRYTK--SPS---DENINKLNIWVPSSDKYKESDGWPVLVYIHGGWLQYSS 134
Q P F T+ +P+ E+ LN+W P + + PVLV+I+GG +
Sbjct: 102 QYVDTLYPGFEGTEMWNPNRELSEDCLYLNVWTPYP---RPTSPTPVLVWIYGGGFYSGA 158
Query: 135 PYSEFFNTNEMFDDEEFTQKYILVTPGYRLNMFGFLSGKELLEEDEASSNFGFWDQRLAI 194
+ ++ + E + +LV+ YR+ FGFL+ L EA N G DQRLA+
Sbjct: 159 SSLDVYDGRFLVQAE----RTVLVSMNYRVGAFGFLA---LPGSREAPGNVGLLDQRLAL 211
Query: 195 EWTYKYIKYFGGNPDKISVGGISAGAYSTFFQLAYELYHPEDNQIIKQALFFSNLVYVQP 254
+W + + FGG+P +++ G SAGA S + L P + +A+ S
Sbjct: 212 QWVQENVAAFGGDPTSVTLFGESAGAAS----VGMHLLSPPSRGLFHRAVLQSGAPNGPW 267
Query: 255 KTI--EECQEQFDEIVEKLDIDPKASG---QEKLAVLRELDAPFIED----FIP--TLTH 303
T+ E + + ++ + P +G E +A LR A + + +P ++
Sbjct: 268 ATVGMGEARRRATQLAHLVGCPPGGTGGNDTELVACLRTRPAQVLVNHEWHVLPQESVFR 327
Query: 304 HTFRAVTDDKFISSTLIKDLDSGEY--ARRLLSIKGDK--FRILCGEVDNEPLKYSLLNT 359
+F V D F+S T +++G++ + L+ + D+ + ++ G SL++
Sbjct: 328 FSFVPVVDGDFLSDTPEALINAGDFHGLQVLVGVVKDEGSYFLVYGAPGFSKDNESLISR 387
Query: 360 PQTLGELPVQVGNYYPKNIVDSLLDLYKVDKLNPASPTLKEDLRVAYGDIIGDGQVYASG 419
+ L V+VG ++ + L+ D L+P P LR A D++GD V
Sbjct: 388 AEFLA--GVRVGVPQVSDLAAEAVVLHYTDWLHPEDPA---RLREALSDVVGDHNVVCPV 442
Query: 420 RGYLHKLVEHGFPSKNIFRYRVSYRAKWLDNHIEPDDRVPHAGDFSLWFYCLRE---GYT 476
+L G ++ Y +RA L + VPH + F + YT
Sbjct: 443 AQLAGRLAAQG---ARVYAYVFEHRASTLSWPLWMG--VPHGYEIEFIFGIPLDPSRNYT 497
Query: 477 DEERIHINEWLQPYLQF 493
EE+I ++ + F
Sbjct: 498 AEEKIFAQRLMRYWANF 514
>CE17905 [R] KOG1516 Carboxylesterase and related proteins
Length = 548
Score = 90.5 bits (223), Expect = 6e-18
Identities = 62/184 (33%), Positives = 90/184 (48%), Gaps = 12/184 (6%)
Query: 41 FAQIPYAEPFTKENRFKRPVPLADDFDYTGDYKEFGLKCPQPSVPNPAFRYTKSPSDENI 100
F IPYAEP RFK+PV + D FG + PQ F T S+E+
Sbjct: 38 FLGIPYAEPPIGALRFKKPVAHRK-WTEPLDCVRFGPRSPQNDELLGQFVNTVGKSEEHC 96
Query: 101 NKLNIWVPSSDKYKESDGWPVLVYIHGGW--LQYSSPYSEFFNTNEMFDDEEFTQKYILV 158
LN++ P + + DG+PV+V+IHGG + SS Y + T+ ++V
Sbjct: 97 LSLNVFTPKWESNEWPDGFPVMVFIHGGGFAVHSSSNYGCASIARNLC-----TKDVVVV 151
Query: 159 TPGYRLNMFGFLSGKELLEEDEASSNFGFWDQRLAIEWTYKYIKYFGGNPDKISVGGISA 218
T YRL + GF + ++ N G WDQ A+EW + I+ F G+PD +++ G SA
Sbjct: 152 TINYRLGVLGFFT----TGDEVCRGNLGLWDQTAALEWVQENIQSFRGDPDNVTIFGQSA 207
Query: 219 GAYS 222
G S
Sbjct: 208 GGAS 211
>7291308 [R] KOG1516 Carboxylesterase and related proteins
Length = 562
Score = 90.1 bits (222), Expect = 8e-18
Identities = 75/243 (30%), Positives = 113/243 (45%), Gaps = 35/243 (14%)
Query: 2 GQVVSTEGTTPFPISIP-GQGTLTGYTFKSPRTNNVTTHRFAQIPYAEPFTKENRFKRPV 60
G+++ T + + +P QG L G K N + + F +PYAEP E RF+ P
Sbjct: 7 GRLIFTRFCSSMKVKVPVKQGVLVGRQKKL--VNGLEYNSFLGVPYAEPPVGELRFRSPR 64
Query: 61 PLADDFDYTGDYKEFGLKCPQPSVPNPAFRYTKSP------SDENINKLNIWVPSSDKYK 114
PL +++ L C + + Y + P E+ LN++ P +
Sbjct: 65 PLER-------FQKQELDCSKEGNVS----YQRDPFTLEVAGSEDCLFLNVYAPKVKSTR 113
Query: 115 ESDGWPVLVYIHGGWLQYSSPYSEFFNTNEMFDDEEFTQKYILVTPGYRLNMFGFLSGKE 174
PV+V+IHGG + + S+F F + Q+ I+VT YRL GFLS
Sbjct: 114 TP--LPVMVWIHGGGFFFGNGNSDFH-----FPAKLMEQEVIVVTLNYRLGALGFLS--- 163
Query: 175 LLEEDEASSNFGFWDQRLAIEWTYKYIKYFGGNPDKISVGGISAGAYS----TFFQLAYE 230
L E+ N G DQRLA+EW + I F G+P+ +++ G SAG S TF + A
Sbjct: 164 -LPEEGIHGNMGLKDQRLALEWVQENIASFNGDPNNVTLFGESAGGSSVHLHTFARHAKR 222
Query: 231 LYH 233
L+H
Sbjct: 223 LFH 225
>7302992 [R] KOG1516 Carboxylesterase and related proteins
Length = 507
Score = 88.6 bits (218), Expect = 2e-17
Identities = 75/252 (29%), Positives = 115/252 (44%), Gaps = 22/252 (8%)
Query: 41 FAQIPYAEPFTKENRFKRPVPLADDFDYTGDYKEFGLKCPQPSVPNPAFRYTKSPSDENI 100
F IP+A+P R K PVP + ++ D C Q S + E+
Sbjct: 46 FMGIPFAQPPVGPLRLKNPVP-NEPWEGVLDAGAAKDSCIQRSYFAKEWGLM---GVEDC 101
Query: 101 NKLNIWVPSSDKYKESDGWPVLVYIHGGWLQYSSPYSEFFNTNEMFDDEEFTQKYILVTP 160
LN++ P K + D PV+VYIHGG S + + D T K ++VT
Sbjct: 102 LYLNVYRP---KNRAEDKLPVMVYIHGGGFFSGSAHPMASGPEYLMD----TNKVVMVTM 154
Query: 161 GYRLNMFGFLSGKELLEEDEASSNFGFWDQRLAIEWTYKYIKYFGGNPDKISVGGISAGA 220
YRL FGFLS ++ NFGF DQRLA++W K+I FGG+P K++V G SAG
Sbjct: 155 NYRLGPFGFLS----TGDEHMPGNFGFKDQRLALQWIQKHIATFGGDPKKVTVLGHSAGG 210
Query: 221 YSTFFQLAYELYHPEDNQIIKQALFFSNLVYVQP-KTIEECQEQFDEIVEKLDID--PKA 277
S + P + + ++ + +++ K +++ Q + ++L ID
Sbjct: 211 ISAHL----HMISPNSKGLFQNSMSLTGTMFLSAMKILKDPLSQARRLGKELAIDQAESL 266
Query: 278 SGQEKLAVLREL 289
S Q+ LR +
Sbjct: 267 SSQDLAEALRNV 278
>CE07347 [R] KOG1516 Carboxylesterase and related proteins
Length = 571
Score = 87.0 bits (214), Expect = 6e-17
Identities = 73/248 (29%), Positives = 112/248 (44%), Gaps = 37/248 (14%)
Query: 10 TTPFPISIPGQGTLTGYTFKSPRTNNVTTHRFAQIPYAEPFTKENRFKRPVPLADDFDYT 69
TTP+ G + G+ KS T + H F I Y P RF++P P+
Sbjct: 25 TTPY-------GPIVGFEHKSTVTGS-KYHVFLGIRYGNPPDHIYRFQKPEPVEKWPHIN 76
Query: 70 GDYKEFGLKCPQPSVPNPAFRYTKSPSDENINK------LNIWVPSSDKYKESDGWPVLV 123
D F C +P+ +S +E +N LNI P K K+ PVLV
Sbjct: 77 HDATHFRASC----IPS-----LRSELEEQVNYSEDCLFLNIVTPPDAKEKKL---PVLV 124
Query: 124 YIHGGWLQYSSPYSEFFNTNEMFDDEEFTQKYILVTPGYRLNMFGFLSGKELLEEDEASS 183
+IHGG Q+ + + D ++ I V+ YRL GF + + E
Sbjct: 125 FIHGGGFQFGDTSMIGY---QKAADNFVSKDIIFVSIQYRLGPLGFFT----TGDSEIPG 177
Query: 184 NFGFWDQRLAIEWTYKYIKYFGGNPDKISVGGISAGAYSTFFQLAYELYHPEDNQIIKQA 243
N G WDQ LA+++ ++ + FGG+PD+I++ G SAGA S ++ LY P + + QA
Sbjct: 178 NMGLWDQTLALQFLHEVLPDFGGDPDRITLAGHSAGAAS----VSALLYSPHSDHLFSQA 233
Query: 244 LFFSNLVY 251
+ S ++
Sbjct: 234 IQLSGSIF 241
>7297440 [R] KOG1516 Carboxylesterase and related proteins
Length = 625
Score = 87.0 bits (214), Expect = 6e-17
Identities = 78/281 (27%), Positives = 122/281 (42%), Gaps = 29/281 (10%)
Query: 15 ISIPGQGTLTGYTFKSPRTNNVTTHRFAQIPYAEPFTKENRFKRPVPLADDFDYTGDYKE 74
+ +P G++ G ++ T +F + YAEP T +RFK P P+ + ++ D
Sbjct: 36 VELPTLGSIQGKILETAWTKREVL-QFVDVRYAEPPTGLHRFKAPRPI-EPWEDVMDATA 93
Query: 75 FGLKCPQPSVPNPAFRYTKSPSDENINKLNIWVPSSDKYKESDGWPVLVYIHGGWLQYSS 134
+ CP + R E+ + I P+ + PVLVYIHG +L S
Sbjct: 94 EKIGCPSVVSMDSLRRLDDVLDVEDCLTMTITTPNV-----TSRLPVLVYIHGEYLYEGS 148
Query: 135 PYSEFFNTNEMFDDEEFTQKYILVTPGYRLNMFGFLSGKELLEEDEASSNFGFWDQRLAI 194
+E D + +LVTP YRL FGFLS K DE N GF D LA+
Sbjct: 149 -------NSEAPPDYLLEKDVVLVTPQYRLGPFGFLSTKT----DEIPGNAGFLDIFLAL 197
Query: 195 EWTYKYIKYFGGNPDKISVGGISAGAYSTFFQLAYELYHPEDNQIIKQALFFSNLVYVQP 254
++ +IKYFGG+P +++V G GA L + Q ++ S +
Sbjct: 198 QFVKHFIKYFGGDPSRVTVAGQVGGAAIAHL---LTLSPVVQRGLFHQVIYHSGSAIMPI 254
Query: 255 KTIEECQEQFDEIVEKLDIDPKASGQEKLAVLRELDAPFIE 295
E+ ++ EI +K D K+ +R+L+ +E
Sbjct: 255 FLEEDPRKHAQEIAKKADC--------KMVTVRDLNTCLME 287
>Hs7662470 [R] KOG1516 Carboxylesterase and related proteins
Length = 823
Score = 85.1 bits (209), Expect = 2e-16
Identities = 66/199 (33%), Positives = 95/199 (47%), Gaps = 33/199 (16%)
Query: 40 RFAQIPYAEPFTKENRFKRPVPLADDFDYTGDYKEFGLKCPQ-------PSVPNPAF--- 89
+F +PYA P T E RF+ P P + D + +F CPQ P V P +
Sbjct: 79 QFLGVPYAAPPTGERRFQPPEPPSPWSDIR-NATQFAPVCPQNIIDGRLPEVMLPVWFTN 137
Query: 90 ------RYTKSPSDENINKLNIWVPSSDKYKESDG-WPVLVYIHGGWLQYSSPYSEFFNT 142
Y + S++ + LNI+VP+ D ++S G PV+VYIHGG S T
Sbjct: 138 NLDVVSSYVQDQSEDCLY-LNIYVPTEDDIRDSGGPKPVMVYIHGG--------SYMEGT 188
Query: 143 NEMFDDEEFTQ--KYILVTPGYRLNMFGFLSGKELLEEDEASSNFGFWDQRLAIEWTYKY 200
++D I++T YRL + GFLS + A N+G D A+ WT +
Sbjct: 189 GNLYDGSVLASYGNVIVITVNYRLGVLGFLS----TGDQAAKGNYGLLDLIQALRWTSEN 244
Query: 201 IKYFGGNPDKISVGGISAG 219
I +FGG+P +I+V G AG
Sbjct: 245 IGFFGGDPLRITVFGSGAG 263
>Hs4502771_1 [R] KOG1516 Carboxylesterase and related proteins
Length = 556
Score = 84.7 bits (208), Expect = 3e-16
Identities = 69/221 (31%), Positives = 107/221 (48%), Gaps = 21/221 (9%)
Query: 41 FAQIPYAEPFTKENRFKRPVPLADDFDYTGDYKEFGLKCPQPSVPNPAFRYTKSPSDENI 100
F IP+A P TK +P P + T K F +C Q ++ + + DE+
Sbjct: 53 FKGIPFAAP-TKALENPQPHP---GWQGTLKAKNFKKRCLQATITQDS-----TYGDEDC 103
Query: 101 NKLNIWVPSSDKYKESDGWPVLVYIHGGWLQYSSPYSEFFNTNEMFDDEEFTQK--YILV 158
LNIWVP K D PV+++I+GG S + F N ++D EE + I+V
Sbjct: 104 LYLNIWVPQGRKQVSRD-LPVMIWIYGGAFLMGSGHGANFLNNYLYDGEEIATRGNVIVV 162
Query: 159 TPGYRLNMFGFLSGKELLEEDEASSNFGFWDQRLAIEWTYKYIKYFGGNPDKISVGGISA 218
T YR+ GFLS + N+G DQ +AI W + I FGG+P+ I++ G SA
Sbjct: 163 TFNYRVGPLGFLSTGDA----NLPGNYGLRDQHMAIAWVKRNIAAFGGDPNNITLFGESA 218
Query: 219 GAYSTFFQLAYELYHPEDNQIIKQALFFSNLVYVQPKTIEE 259
G S ++ + P + +I++A+ S V + P I++
Sbjct: 219 GGAS----VSLQTLSPYNKGLIRRAISQSG-VALSPWVIQK 254
>CE28131 [T] KOG4389 Acetylcholinesterase/Butyrylcholinesterase
Length = 607
Score = 84.3 bits (207), Expect = 4e-16
Identities = 64/196 (32%), Positives = 94/196 (47%), Gaps = 24/196 (12%)
Query: 35 NVTTHRFAQIPYAEPFTKENRFKRPVPLADDFDYTGDYKEFGLKCPQ------PSVPNPA 88
N F +P+AEP E+RFK+P P A ++ T C Q P+
Sbjct: 50 NKRVRSFLGVPFAEPPINEHRFKKPTP-ARPWNGTISANTLSPACFQGRDSYDPTFWGSE 108
Query: 89 FRYTKSPSDENINKLNIWVPSSDKYKESDGWPVLVYIHGGWLQYSSPYSEFFNTNEMFDD 148
+P E+ +NIW P+ D Y + VLV++ GG Y SP + ++D
Sbjct: 109 MWNANTPVSEDCLYVNIWAPA-DAYNLT----VLVWLFGGGFWYGSP------SLLLYDG 157
Query: 149 EEFTQK--YILVTPGYRLNMFGFLSGKELLEEDEASSNFGFWDQRLAIEWTYKYIKYFGG 206
+E + I+V YR+ FG+L L+ ++ N G DQ+LA+ W +I FGG
Sbjct: 158 KELATRGNVIVVNINYRVGPFGYL----FLDHEDVPGNMGMLDQQLALYWIRDHIFSFGG 213
Query: 207 NPDKISVGGISAGAYS 222
NP +IS+ G SAGA S
Sbjct: 214 NPARISLVGESAGAAS 229
>7291738 [R] KOG1516 Carboxylesterase and related proteins
Length = 603
Score = 84.0 bits (206), Expect = 5e-16
Identities = 75/230 (32%), Positives = 108/230 (46%), Gaps = 42/230 (18%)
Query: 12 PFPISIPGQGTLTGYTFKSPRTNNVTTHRFAQIPYAEPFTKENRFKRP----VPLADDFD 67
PF I IPG G ++G K RT N+ + + +A RF+ P P F+
Sbjct: 32 PF-IHIPGNGVISGTYLKMFRTQNIKAYLGIRYAHAR------RFQPPDIELTPWKGIFN 84
Query: 68 YTGDYKEFGLKCPQPSVPNPA------FRYTKSPS---------DENINKLNIWVPSSDK 112
T F C Q ++P+ + +S S +EN LN++VP D
Sbjct: 85 AT----VFQPDCWQNAMPSVGKETEQILKIIQSDSSAQDAERKYEENCLYLNVFVP--DG 138
Query: 113 YKESDGWPVLVYIHGGWLQYSSPYSEFFNTNEMFDDEEFTQKYILVTPGYRLNMFGFLSG 172
E +G+ V+V+IH G SP E F F QK I+VT YRLN+FGF +
Sbjct: 139 LPEINGYAVVVWIHSGDFSTGSPADV-----EPFQ-LVFKQKVIVVTFSYRLNIFGFFT- 191
Query: 173 KELLEEDEASSNFGFWDQRLAIEWTYKYIKYFGGNPDKISVGGISAGAYS 222
++ EA N+G DQ A+ W K I +FGG+ ++I++ G AGA S
Sbjct: 192 ---TDDGEAQGNYGLMDQSAALYWVKKNINFFGGDSNRITLMGHDAGAVS 238
>7294607 [R] KOG1516 Carboxylesterase and related proteins
Length = 544
Score = 83.6 bits (205), Expect = 7e-16
Identities = 69/236 (29%), Positives = 109/236 (45%), Gaps = 27/236 (11%)
Query: 12 PFPISIPGQGTLTGYTFKSPRTNNVTTHRFAQIPYAEPFTKENRFKRPVPLADDFDYTGD 71
P + +P QG L G +N + + + IPYAEP T + RF+ P P + D
Sbjct: 27 PLLVQLP-QGKLRG-------RDNGSYYSYESIPYAEPPTGDLRFEAPEPYKQKWSDIFD 78
Query: 72 YKEFGLKCPQPSVPNPAFRYTKSPSDENINKLNIWVPSSDKYKESDGWPVLVYIHGGWLQ 131
+ + C Q P K +E+ ++++ P + K + +PV+ +IHGG
Sbjct: 79 ATKTPVACLQWDQFTPGAN--KLVGEEDCLTVSVYKPKNSK---RNSFPVVAHIHGGAFM 133
Query: 132 YSSPYSEFFNTNEMFDDEEFTQKYILVTPGYRLNMFGFLSGKELLEEDEASSNFGFWDQR 191
+ + + N +E E K+ILV YRL GF+S + + N+G DQR
Sbjct: 134 FGAAWQ---NGHENVMREG---KFILVKISYRLGPLGFVS----TGDRDLPGNYGLKDQR 183
Query: 192 LAIEWTYKYIKYFGGNPDKISVGGISAGAYSTFFQLAYELYHPEDNQIIKQALFFS 247
LA++W + I FGG P + + G SAG S Q+ E + Q+ + A FS
Sbjct: 184 LALKWIKQNIASFGGEPQNVLLVGHSAGGASVHLQMLRE----DFGQLARAAFSFS 235
>Hs4557351 [T] KOG4389 Acetylcholinesterase/Butyrylcholinesterase
Length = 602
Score = 81.6 bits (200), Expect = 3e-15
Identities = 108/430 (25%), Positives = 173/430 (40%), Gaps = 43/430 (10%)
Query: 37 TTHRFAQIPYAEPFTKENRFKRPVPLADDFDYTGDYKEFGLKCPQPSVPNPAFRYTK--- 93
T F IPYA+P RFK+P L D K C P F ++
Sbjct: 52 TVTAFLGIPYAQPPLGRLRFKKPQSLTKWSDIWNATKYANSCCQNIDQSFPGFHGSEMWN 111
Query: 94 --SPSDENINKLNIWVPSSDKYKESDGWPVLVYIHGGWLQYSSPYSEFFNTNEMFDDEEF 151
+ E+ LN+W+P+ + VL++I+GG Q + ++ + E
Sbjct: 112 PNTDLSEDCLYLNVWIPAPKPKNAT----VLIWIYGGGFQTGTSSLHVYDGKFLARVE-- 165
Query: 152 TQKYILVTPGYRLNMFGFLSGKELLEEDEASSNFGFWDQRLAIEWTYKYIKYFGGNPDKI 211
+ I+V+ YR+ GFL+ L EA N G +DQ+LA++W K I FGGNP +
Sbjct: 166 --RVIVVSMNYRVGALGFLA---LPGNPEAPGNMGLFDQQLALQWVQKNIAAFGGNPKSV 220
Query: 212 SVGGISAGAYSTFFQLAYELYHPEDNQIIKQALFFSNLVYVQPKTIEECQEQFDEIVE-- 269
++ G SAGA S ++ L P + + +A+ S + P + E + +
Sbjct: 221 TLFGESAGAAS----VSLHLLSPGSHSLFTRAILQSG-SFNAPWAVTSLYEARNRTLNLA 275
Query: 270 KLDIDPKASGQEKLAVLRELDAPFI---EDFI---PTLTHHTFRAVTDDKFISSTLIKDL 323
KL + + E + LR D I E F+ T F D F++ L
Sbjct: 276 KLTGCSRENETEIIKCLRNKDPQEILLNEAFVVPYGTPLSVNFGPTVDGDFLTDMPDILL 335
Query: 324 DSGEYARRLLSIKGDKFRILCGEVDNEPLKYSLLNTPQTLGELPVQVGNYYP---KNIVD 380
+ G++ + + + +K V P N+ T E + ++P + +
Sbjct: 336 ELGQFKKTQILVGVNKDEGTAFLVYGAPGFSKDNNSIITRKEFQEGLKIFFPGVSEFGKE 395
Query: 381 SLLDLYK--VDKLNPASPTLKEDLRVAYGDIIGDGQVYASGRGYLHKLVEHGFPSKNIFR 438
S+L Y VD P E+ R A GD++GD + K E G N F
Sbjct: 396 SILFHYTDWVDDQRP------ENYREALGDVVGDYNFICPALEFTKKFSEWG---NNAFF 446
Query: 439 YRVSYRAKWL 448
Y +R+ L
Sbjct: 447 YYFEHRSSKL 456
>7302991 [R] KOG1516 Carboxylesterase and related proteins
Length = 803
Score = 81.6 bits (200), Expect = 3e-15
Identities = 82/280 (29%), Positives = 116/280 (41%), Gaps = 32/280 (11%)
Query: 18 PGQGTLTGYTFKSPRTNNVTTHRFAQIPYAEPFTKENRFKRPVPLADDFDYTGDYKEFGL 77
P G L G + ++ F IPYA P + RF P + G Y
Sbjct: 32 PSVGCLKGTNLQGYQSERFEA--FMGIPYALPPIGDLRFSNPKVMPK---LLGMYDASAP 86
Query: 78 K--CPQPS--VPNPAFRYTKSPSDENINKLNIWVPSSDKYKESDGWPVLVYIHGGWLQYS 133
K C Q + +P P DE+ LN++ P K PV+VYIHGG
Sbjct: 87 KMDCIQKNYLLPTPVVY-----GDEDCLYLNVYRPEIRK----SALPVMVYIHGGGFFGG 137
Query: 134 SPYSEFFNTNEMFDDEEFTQKYILVTPGYRLNMFGFLSGKELLEEDEASSNFGFWDQRLA 193
S D E ILVT YRL FGFLS ++ + S NFG DQ LA
Sbjct: 138 SAGPGVTGPEYFMDSGEV----ILVTMAYRLGPFGFLSTQDAV----MSGNFGLKDQNLA 189
Query: 194 IEWTYKYIKYFGGNPDKISVGGISAGAYSTFFQLAYELYHPEDNQIIKQALFFSNLVYVQ 253
+ W + I++FGG+P ++++ G SAG + L P + + + + S V
Sbjct: 190 LRWVQRNIRFFGGDPQRVTIFGQSAGGVAAHM----HLLSPRSHGLFHRVISMSGTANVP 245
Query: 254 PKTIEECQEQFDEIVEKLDI-DPKASGQEKLA-VLRELDA 291
E+ EQ + E D+ D + KL LR ++A
Sbjct: 246 FAIAEQPLEQARLLAEFADVPDARNLSTVKLTKALRRINA 285
>7299402 [R] KOG1516 Carboxylesterase and related proteins
Length = 550
Score = 80.1 bits (196), Expect = 8e-15
Identities = 60/187 (32%), Positives = 86/187 (45%), Gaps = 20/187 (10%)
Query: 36 VTTHRFAQIPYAEPFTKENRFKRPVPLADDFDYTGDYKEFGLKCPQPSVPNPAFRYTKSP 95
V H F I YAEP + RF P P+ D E G CPQP +
Sbjct: 41 VNFHAFRGIRYAEPPLGDLRFVNPQPVKPWSPKIFDASEDGPMCPQPWD-------NMTD 93
Query: 96 SDENINKLNIWVPSSDKYKESDGWPVLVYIHGGWLQYSSPYSEFFNTNEMFDDEEFTQKY 155
E+ +LN++ + PV+V++H G S S++ E F D +
Sbjct: 94 VSEDCLRLNVYTKDLKGRR-----PVIVFLHPGGFYVFSGQSKYLAGPEHFMDRDC---- 144
Query: 156 ILVTPGYRLNMFGFLSGKELLEEDEASSNFGFWDQRLAIEWTYKYIKYFGGNPDKISVGG 215
+LV+ YRL GFL+ EA N G DQ LA+ W ++I+ FGG+PD +++ G
Sbjct: 145 VLVSLNYRLGSLGFLA----TGSKEAPGNAGLKDQVLALRWIQQHIQRFGGDPDSVTLLG 200
Query: 216 ISAGAYS 222
SAG+ S
Sbjct: 201 YSAGSIS 207
>7298797 [R] KOG1516 Carboxylesterase and related proteins
Length = 542
Score = 79.7 bits (195), Expect = 1e-14
Identities = 63/191 (32%), Positives = 91/191 (46%), Gaps = 18/191 (9%)
Query: 41 FAQIPYAEPFTKENRFKRPVPLADDFDYTGDYKEFGLKCPQPSVPNPAFRYTKSPSDENI 100
F +IP+A+P E RF+ PVP AD + D + K Q + E+
Sbjct: 35 FEKIPFAKPPLGELRFRAPVP-ADPWSGVLDCTHYAEKPTQRGLLTREIE-----GGEDC 88
Query: 101 NKLNIWVPSSDKYKESDGWPVLVYIHGGWLQYSSPYSEFFNTNEMFDDEEF-TQKYILVT 159
LN++ S + K PV+VYI+GG T E++ + F T+ +LVT
Sbjct: 89 LYLNVY---SKQLKSEKPLPVMVYIYGGAFTVGEA------TRELYGPDYFMTKDVVLVT 139
Query: 160 PGYRLNMFGFLSGKELLEEDEASSNFGFWDQRLAIEWTYKYIKYFGGNPDKISVGGISAG 219
YR++ GFLS K+ + N G DQ LA++W +YI F G+ I+V G SAG
Sbjct: 140 LNYRVDCLGFLSLKD--PSLKVPGNAGLKDQVLALKWVKQYISNFNGDDSNITVFGESAG 197
Query: 220 AYSTFFQLAYE 230
ST F + E
Sbjct: 198 GCSTHFMMCTE 208
>Hs20554181 [R] KOG1516 Carboxylesterase and related proteins
Length = 816
Score = 79.0 bits (193), Expect = 2e-14
Identities = 64/229 (27%), Positives = 99/229 (42%), Gaps = 37/229 (16%)
Query: 13 FPISIPGQGTLTGYTFKSPRTNNVTTHRFAQIPYAEPFTKENRFKRPVPLADDFDYTG-- 70
+P+ G + G P ++ +PYA P T E RF+ P P + +TG
Sbjct: 45 YPVVNTNYGKIRGLRTPLPNEILGPVEQYLGVPYASPPTGERRFQPPEPPSS---WTGIR 101
Query: 71 DYKEFGLKCPQPSVPNPAFRYTKSP----------------SDENINKLNIWVPSSDK-Y 113
+ +F CPQ + + + P +E+ LNI+VP+ D +
Sbjct: 102 NTTQFAAVCPQ-HLDERSLLHDMLPIWFTANLDTLMTYVQDQNEDCLYLNIYVPTEDDIH 160
Query: 114 KESDGWPVLVYIHGGWLQYSSPYSEFFNTNEMFDDEEFTQ--KYILVTPGYRLNMFGFLS 171
++ PV+VYIHGG S T M D I++T YRL + GFLS
Sbjct: 161 DQNSKKPVMVYIHGG--------SYMEGTGNMIDGSILASYGNVIVITINYRLGILGFLS 212
Query: 172 GKELLEEDEASSNFGFWDQRLAIEWTYKYIKYFGGNPDKISVGGISAGA 220
+ A N+G DQ A+ W + + FGG+P ++++ G AGA
Sbjct: 213 ----TGDQAAKGNYGLLDQIQALRWIEENVGAFGGDPKRVTIFGSGAGA 257
>7298803 [R] KOG1516 Carboxylesterase and related proteins
Length = 567
Score = 78.6 bits (192), Expect = 2e-14
Identities = 62/207 (29%), Positives = 97/207 (45%), Gaps = 18/207 (8%)
Query: 21 GTLTGYTFKSPRTNNVTTHRFAQIPYAEPFTKENRFKRPVPLADDFDYTGDYKEFGLKCP 80
G + G ++S NN + F IP+A+P E RFK PV + ++ D K
Sbjct: 33 GKVKGVKWQSIYGNNY--YSFEGIPFAKPPVGELRFKAPV----EPEHWSDVKRCTHVRA 86
Query: 81 QPSVPNPAFRYTKSPSDENINKLNIWVPSSDKYKESDGWPVLVYIHGGWLQYSSPYSEFF 140
+P N + + E+ LN++ ++ PVLV+I+GG Q + +
Sbjct: 87 KPCQVNIVLKQVQG--SEDCLYLNVYTRELHPHRPL---PVLVWIYGGGFQMGEASRDLY 141
Query: 141 NTNEMFDDEEFTQKYILVTPGYRLNMFGFLSGKELLEEDEASSNFGFWDQRLAIEWTYKY 200
+ D + +LV YRL GFLS + EE + N G DQ +A+ W +
Sbjct: 142 SP-----DYIMMEHVVLVVISYRLGALGFLSLAD--EELDVPGNAGLKDQVMALRWVKRN 194
Query: 201 IKYFGGNPDKISVGGISAGAYSTFFQL 227
++FGG+PD I+V G SAG ST + +
Sbjct: 195 CQFFGGDPDNITVFGESAGGASTHYMM 221
>CE09376 [R] KOG1516 Carboxylesterase and related proteins
Length = 504
Score = 78.2 bits (191), Expect = 3e-14
Identities = 45/133 (33%), Positives = 76/133 (56%), Gaps = 12/133 (9%)
Query: 94 SPSDENINKLNIWVPSSDKYK-ESDGWPVLVYIHGGWLQY--SSPYSEFFNTNEMFDDEE 150
SP + LN++ P + ++ G PV+V+IHGG ++ S+ Y ++ + +
Sbjct: 71 SPEEAGCLTLNVFSPRQPSLEFKTGGRPVMVFIHGGGFEFGGSADYCDYSLSGTLP---- 126
Query: 151 FTQKYILVTPGYRLNMFGFLSGKELLEEDEASSNFGFWDQRLAIEWTYKYIKYFGGNPDK 210
+ ++V+ YRL +FGFL+ + + + NFG WDQ LA++W K+I FGG+P+
Sbjct: 127 -LKDVVVVSINYRLGVFGFLTTGDSV----CNGNFGLWDQTLALKWVQKHISSFGGDPNC 181
Query: 211 ISVGGISAGAYST 223
++V G SAG ST
Sbjct: 182 VTVFGQSAGGAST 194
>7290457 [R] KOG1516 Carboxylesterase and related proteins
Length = 527
Score = 78.2 bits (191), Expect = 3e-14
Identities = 86/339 (25%), Positives = 141/339 (41%), Gaps = 28/339 (8%)
Query: 44 IPYAEPFTKENRFKRPVPLADDFDYTGDYKEFGLKCPQPSVPNPAFRYTKS-PSDENINK 102
+PYAEP + RF+ PVP A + + +K + FR E+
Sbjct: 3 VPYAEPPLDDLRFRPPVPKAP-----WEGERLAIKDAPICLQRDPFRRDMILEGSEDCLY 57
Query: 103 LNIWVPSSDKYKESDGWPVLVYIHGGWLQYSSPYSEFFNTNEMFDDEEFTQKYILVTPGY 162
LN++ P ++ + + PV+V+ HGG Q S S F+ + + D + +LV+ +
Sbjct: 58 LNVYTP--ERPRTNGSLPVMVWFHGGGWQCGSGISSFYGPDFLLDHD-----IVLVSANF 110
Query: 163 RLNMFGFLSGKELLEEDEASSNFGFWDQRLAIEWTYKYIKYFGGNPDKISVGGISAGAYS 222
RL GFLS + L + N G DQ + W I FGG+P+ ++V G SAG S
Sbjct: 111 RLGPLGFLSTETL----DCPGNNGLKDQLEVLHWVRANIASFGGDPNSVTVFGESAGGAS 166
Query: 223 TFFQLAYELYHPEDNQIIKQALFFSNLVYVQPKTIEECQEQFDEIVEKLDIDPKASGQEK 282
+ + E ++ I Q+ + N + QP + ++ + + EK
Sbjct: 167 VTYHMLSEKSRGLLHRGIAQSGTYFN-PWAQPAHKGVAAGRATKLAQIVGCGNAGEWPEK 225
Query: 283 LAVLRELDAPFIEDFIPTLTHHTFRAVTDDKFISSTLIKDLDSGEY----ARRLLSIKGD 338
L LR+ A ED + +L + F D +++ G + R+ G
Sbjct: 226 LECLRKKPA---EDIVASL-YDMFVWDFDPMIPFPPVVEPEHDGAFLTVAPRQAAKPHGL 281
Query: 339 KFRILCGEVDNEPL--KYSLLNTPQTLGELPVQVGNYYP 375
+ ++ G E L +LLN PQ L E Q P
Sbjct: 282 QLPLMVGATAEEGLLKTAALLNLPQLLAEFKSQFEQVLP 320
>7299734 [T] KOG4389 Acetylcholinesterase/Butyrylcholinesterase
Length = 649
Score = 77.0 bits (188), Expect = 7e-14
Identities = 61/227 (26%), Positives = 95/227 (40%), Gaps = 43/227 (18%)
Query: 39 HRFAQIPYAEPFTKENRFKRPVPLADDFDYTGDYKEFGLKCPQ------PSVPNPAFRYT 92
H + IPYA+P ++ RF++PVP A+ + D C Q P
Sbjct: 65 HVYTGIPYAKPPVEDLRFRKPVP-AEPWHGVLDATRLSATCVQERYEYFPGFSGEEIWNP 123
Query: 93 KSPSDENINKLNIWVPSSDKYKE-----------------------------SDGWPVLV 123
+ E+ +N+W P+ + + ++G P+L+
Sbjct: 124 NTNVSEDCLYINVWAPAKARLRHGRGANGGEHPNGKQADTDHLIHNGNPQNTTNGLPILI 183
Query: 124 YIHGGWLQYSSPYSEFFNTNEMFDDEEFTQKYILVTPGYRLNMFGFLS-GKELLEE--DE 180
+I+GG S + +N + M I+ + YR+ FGFL E+ E +E
Sbjct: 184 WIYGGGFMTGSATLDIYNADIM----AAVGNVIVASFQYRVGAFGFLHLAPEMPSEFAEE 239
Query: 181 ASSNFGFWDQRLAIEWTYKYIKYFGGNPDKISVGGISAGAYSTFFQL 227
A N G WDQ LAI W FGGNP+ +++ G SAG+ S QL
Sbjct: 240 APGNVGLWDQALAIRWLKDNAHAFGGNPEWMTLFGESAGSSSVNAQL 286
>CE26734 [T] KOG4389 Acetylcholinesterase/Butyrylcholinesterase
Length = 602
Score = 76.6 bits (187), Expect = 9e-14
Identities = 67/215 (31%), Positives = 97/215 (44%), Gaps = 28/215 (13%)
Query: 41 FAQIPYAEPFTKENRFKRPVPLADDFDYTGDY---KEFGLKCPQPSVPNPAFRYTK---- 93
F +P+AEP ++ RF++P + + G Y K N +F ++
Sbjct: 51 FFGVPFAEPAVEDFRFRKP---REKKQWRGLYDATKPANACFQTRDNYNTSFWGSEMWNA 107
Query: 94 -SPSDENINKLNIWVPSSDKYKESDGWPVLVYIHGGWLQYSSPYSEFFNTNEMFDDEEFT 152
+ E+ LNIW P+ D Y + V+V+ GG SP ++ + T
Sbjct: 108 NTQISEDCLYLNIWAPA-DAYNLT----VMVWFFGGGFYSGSPSLSIYDGKALTS----T 158
Query: 153 QKYILVTPGYRLNMFGFLSGKELLEEDEASSNFGFWDQRLAIEWTYKYIKYFGGNPDKIS 212
Q I+V YRL FGFL L +A N G DQ+LA+ W + I FGGNPDK++
Sbjct: 159 QNVIVVNINYRLGPFGFL----YLGHPDAPGNMGLLDQQLALHWVRQNIVSFGGNPDKVA 214
Query: 213 VGGISAGAYSTFFQLAYELYHPEDNQIIKQALFFS 247
V G SAGA S + L P + K A+ S
Sbjct: 215 VFGQSAGAAS----IVAHLIAPGSRGLFKNAILQS 245
>CE14345 [R] KOG1516 Carboxylesterase and related proteins
Length = 578
Score = 76.6 bits (187), Expect = 9e-14
Identities = 65/210 (30%), Positives = 95/210 (44%), Gaps = 32/210 (15%)
Query: 20 QGTLTGYTFKSPRTNNVTTHRFAQIPYAEPFTKENRFKRPVP--------LADDFDYTGD 71
QG L G+ K+ + + F IPYAEP E RF++P P + +
Sbjct: 22 QGLLEGFRVKTAKGDLCDV--FHGIPYAEPPVGELRFQKPQPPKAWEGIRKCNKYPNRSI 79
Query: 72 YKEFGLKCPQPSVPNPAFRYTKSPSDENINKLNIWVPSSDKYKESDGWPVLVYIHGG-WL 130
+KE PS + E+ LN++ P K +E +PVL YIHGG ++
Sbjct: 80 HKEMPWDKALPS----------ANQSEDCLYLNVFAP---KIREDKKYPVLFYIHGGGYV 126
Query: 131 QYSSPYSEFFNTNEMFDDEEFTQKYILVTPGYRLNMFGFLSGKELLEEDEASSNFGFWDQ 190
S+ N ++ E I+VT YRL GFLS +D N+G +D
Sbjct: 127 MDSAERYTAKNICKLLVSREI----IVVTFHYRLGFLGFLS----TGDDVCPGNYGLFDM 178
Query: 191 RLAIEWTYKYIKYFGGNPDKISVGGISAGA 220
A+ W + I FGG+P+ I++ G SAGA
Sbjct: 179 LEAMRWVHANISSFGGDPENITLSGQSAGA 208
>CE14343 [R] KOG1516 Carboxylesterase and related proteins
Length = 658
Score = 76.6 bits (187), Expect = 9e-14
Identities = 65/210 (30%), Positives = 95/210 (44%), Gaps = 32/210 (15%)
Query: 20 QGTLTGYTFKSPRTNNVTTHRFAQIPYAEPFTKENRFKRPVP--------LADDFDYTGD 71
QG L G+ K+ + + F IPYAEP E RF++P P + +
Sbjct: 102 QGLLEGFRVKTAKGDLCDV--FHGIPYAEPPVGELRFQKPQPPKAWEGIRKCNKYPNRSI 159
Query: 72 YKEFGLKCPQPSVPNPAFRYTKSPSDENINKLNIWVPSSDKYKESDGWPVLVYIHGG-WL 130
+KE PS + E+ LN++ P K +E +PVL YIHGG ++
Sbjct: 160 HKEMPWDKALPS----------ANQSEDCLYLNVFAP---KIREDKKYPVLFYIHGGGYV 206
Query: 131 QYSSPYSEFFNTNEMFDDEEFTQKYILVTPGYRLNMFGFLSGKELLEEDEASSNFGFWDQ 190
S+ N ++ E I+VT YRL GFLS +D N+G +D
Sbjct: 207 MDSAERYTAKNICKLLVSREI----IVVTFHYRLGFLGFLS----TGDDVCPGNYGLFDM 258
Query: 191 RLAIEWTYKYIKYFGGNPDKISVGGISAGA 220
A+ W + I FGG+P+ I++ G SAGA
Sbjct: 259 LEAMRWVHANISSFGGDPENITLSGQSAGA 288
>7297537 [R] KOG1516 Carboxylesterase and related proteins
Length = 593
Score = 76.6 bits (187), Expect = 9e-14
Identities = 112/442 (25%), Positives = 168/442 (37%), Gaps = 68/442 (15%)
Query: 31 PRTNNVTTHRFAQIPYAEPFTKENRFKRPVPLADDFDYTGDYKEFGLKCPQPSVPNPAFR 90
P + + F IPYA+P RF+ P P+ FD T D G KCPQ +
Sbjct: 72 PSQSGRNFYAFRGIPYAKPPVDRLRFQPPEPVEQWFD-TLDATFDGPKCPQLGL------ 124
Query: 91 YTKSPSDENINKLNIWVPSSDKYKESD-GWPVLVYIHGGWLQYSSPYSEFFNTNEMFDDE 149
E+ ++NI+ + + PV+V+IH G S S+ F + F
Sbjct: 125 -VSGDVSEDCLRVNIYTKELPSESQPNVRRPVIVFIHPGGFYSLSGQSKNFAGPQYF--- 180
Query: 150 EFTQKYILVTPGYRLNMFGFLSGKELLEEDEASSNFGFWDQRLAIEWTYKYIKYFGGNPD 209
++ +LVT YRL GFL+ EA N G DQ + W +I FGG+P
Sbjct: 181 -MNRRLVLVTFNYRLGSLGFLA----TGTREAPGNMGLKDQVQLLRWVKLHISRFGGDPS 235
Query: 210 KISVGGISAGAYSTFFQLAYELYHPEDNQIIKQALFFSNLVYVQ-------------PKT 256
I++ G AGA + + + P + +A+ S V Q T
Sbjct: 236 SITLLGYGAGAMA----VTLHMVSPMSRGLFHKAIVMSGAVTGQWSLPDHQMDVATKQAT 291
Query: 257 IEECQ-EQFDEIVEKLDIDPKASGQEKLAVLRELD--------APFIE-DFIPT--LTHH 304
+ C E E+++ L L + E D P IE DF L
Sbjct: 292 LLHCHTENVTEMMDCLKGKHYLEFANTLPKMFEFDRNNPLILWKPVIEPDFGQERFLVEE 351
Query: 305 TFRAVTDDKFISSTLIKDLDSGEYARRLLSIKGDKFRILCGEVDNEPLK--YSLLNTPQT 362
R+ +D F+ +I + E+ LSI + + E L + + NT
Sbjct: 352 PIRSYQNDDFMKVPIITGMTKDEFVGPALSILQSPTLLSALNENFESLAPVFFMYNTSDA 411
Query: 363 LGELPVQVGNYYPKNIVDSLLDLYKVDKLNPASPTLKEDLRVAYGDIIGDGQVYASGRGY 422
NI L + Y DKL A+ +L E L Y D + +G G
Sbjct: 412 RA-----------CNISQELRNHYFPDKLIDANRSL-EALSNLYSDAL-------TGFG- 451
Query: 423 LHKLVEHGFPSKNIFRYRVSYR 444
+H+ V S ++ YR SY+
Sbjct: 452 IHRFVHLAARSTKVYYYRFSYQ 473
>7298250 [R] KOG1516 Carboxylesterase and related proteins
Length = 875
Score = 76.3 bits (186), Expect = 1e-13
Identities = 63/194 (32%), Positives = 89/194 (45%), Gaps = 38/194 (19%)
Query: 41 FAQIPYAEPFTKENRFKRPVPLADDFDYTG----DYKEFGLKCPQPSVPNPAFRYTKSPS 96
F IPYA P T E RFK P + G +FG CPQP RYT +
Sbjct: 89 FLGIPYALPPTFEGRFKPPRV------HRGWQLLQAVDFGPACPQP------VRYTGATK 136
Query: 97 -----DENINKLNIWVPSSDKYKESDGWPVLVYIHGGWLQYSSPYSEFFN-TNEMFDDEE 150
DE+ LN++ P + + +PV+VYIHGG EF + +F
Sbjct: 137 GIMDMDEDCLYLNVYSPKTGA-GVAQKYPVMVYIHGG---------EFIRGASNLFQGHI 186
Query: 151 FTQKY--ILVTPGYRLNMFGFLSGKELLEEDEASSNFGFWDQRLAIEWTYKYIKYFGGNP 208
Y ++VT YRL GFLS ++ + N+G DQ +A+ W Y I++F G+
Sbjct: 187 LASFYDVVVVTLNYRLGALGFLS----TGDENSPGNYGILDQAMALRWVYDNIEFFNGDR 242
Query: 209 DKISVGGISAGAYS 222
+ I++ G AG S
Sbjct: 243 NSITLFGPGAGGAS 256
>7296094 [R] KOG1516 Carboxylesterase and related proteins
Length = 665
Score = 76.3 bits (186), Expect = 1e-13
Identities = 62/201 (30%), Positives = 87/201 (42%), Gaps = 28/201 (13%)
Query: 28 FKSPRTNNVTTHRFAQIPYAEPFTKENRFKRPV--PLADDFDYTGDYKEFGLKCPQPSVP 85
F++P T + F + YAEP R+ RPV LA DF+ T + G C QP
Sbjct: 66 FRNPSTG---IYSFLGMHYAEPPVGPLRYSRPVYKRLAGDFNAT----KHGPPCIQPHPQ 118
Query: 86 NPAFRYTKSPSDENINKLNIWVPSSDKYKESDGWPVLVYIHGGWLQYSSPYSEFFNTNEM 145
P + DE+ LN++ P E+ G PV V+IH G +Y S
Sbjct: 119 FPQ----RIIGDEDCLLLNVYTPQMPD--ETTGLPVFVWIHPGGYRYGSA--------AQ 164
Query: 146 FDDEEFTQK-YILVTPGYRLNMFGFLSGKELLEEDEASSNFGFWDQRLAIEWTYKYIKYF 204
+D Q+ I+V P YRL G + + N +D A+ W YI YF
Sbjct: 165 YDATPMAQRGAIVVAPQYRLGSLGIMGDGT----KQFDGNLAMFDLAAALRWVTDYISYF 220
Query: 205 GGNPDKISVGGISAGAYSTFF 225
GGNP ++ G +GA S +
Sbjct: 221 GGNPKQVQAIGHGSGAASAMY 241
>CE28655 [R] KOG1516 Carboxylesterase and related proteins
Length = 241
Score = 75.9 bits (185), Expect = 1e-13
Identities = 58/182 (31%), Positives = 89/182 (48%), Gaps = 10/182 (5%)
Query: 41 FAQIPYAEPFTKENRFKRPVPLADDFDYTGDYKEFGLKCPQPSVPNPAFRYTKSPSD--- 97
F +PYAEP E RFK PV + E+G C Q + ++ K+ D
Sbjct: 48 FRGVPYAEPPIGELRFKPPVKKTR-WHQELPAVEYGPPCLQFMDFHKNDKFAKTNMDRQS 106
Query: 98 ENINKLNIWVPSSDKYKESDGWPVLVYIHGGWLQYSSPYSEFFNTNEMFDDEEFTQKYIL 157
E+ LN++ P D ES +P+LV+IHGG + + ++ E+ ++
Sbjct: 107 EDCLYLNVFSPY-DTDDESKTYPILVWIHGG--SFLAGSADTGIDMEVIAANIVSKGIAF 163
Query: 158 VTPGYRLNMFGFLSGKELLEEDEASSNFGFWDQRLAIEWTYKYIKYFGGNPDKISVGGIS 217
V+ YRL GF++ + D+ NFG WD +A++W IK F G+P K++V G S
Sbjct: 164 VSINYRLGPLGFMNYQN---GDKLEGNFGIWDMVMALQWIQSNIKQFNGDPTKVTVMGES 220
Query: 218 AG 219
AG
Sbjct: 221 AG 222
>CE07569 [T] KOG4389 Acetylcholinesterase/Butyrylcholinesterase
Length = 620
Score = 74.7 bits (182), Expect = 3e-13
Identities = 63/237 (26%), Positives = 103/237 (42%), Gaps = 43/237 (18%)
Query: 40 RFAQIPYAEPFTKENRFKRPVP-----------------LADDFDYTGDYKEFGLKCPQP 82
RF IP+AEP RFK+P P + + Y GD+
Sbjct: 44 RFQGIPFAEPPVGNLRFKKPKPKQPWRIPLNATTPPNSCIQSEDTYFGDFY--------- 94
Query: 83 SVPNPAFRYTKSPSDENINKLNIWVPSSDKYKESDGWPVLVYIHGGWLQYSSPYSEFFNT 142
+ E+ LN++VP K + V+V+++GG + T
Sbjct: 95 ---GSTMWNANTKLSEDCLYLNVYVPG--KVDPNKKLAVMVWVYGGGFWSGTA------T 143
Query: 143 NEMFDDEEFT--QKYILVTPGYRLNMFGFLSGKELLEEDEASSNFGFWDQRLAIEWTYKY 200
+++D T + ILV YR+++FGFL + EA N G WDQ LA++W +K
Sbjct: 144 LDVYDGRILTVEENVILVAMNYRVSIFGFL----YMNRPEAPGNMGMWDQLLAMKWVHKN 199
Query: 201 IKYFGGNPDKISVGGISAGAYSTFFQLAYELYHPEDNQIIKQALFFSNLVYVQPKTI 257
I FGG+ +I++ G SAGA S + P ++ I Q+ ++ ++P+ +
Sbjct: 200 IDLFGGDLSRITLFGESAGAASVSIHMLSPKSAPYFHRAIIQSGSATSPWAIEPRDV 256
>7298801 [R] KOG1516 Carboxylesterase and related proteins
Length = 572
Score = 74.7 bits (182), Expect = 3e-13
Identities = 59/190 (31%), Positives = 87/190 (45%), Gaps = 22/190 (11%)
Query: 41 FAQIPYAEPFTKENRFK---RPVPLADDFDYTGDYKEFGLKCPQPSVPNPAFRYTKSPSD 97
F IPYA+P E RFK RP+P ++ D + P+ F + K
Sbjct: 58 FEGIPYAQPPVGELRFKAPQRPIP----WERVRDCSQ-----PKDKAVQVQFVFDKVEGS 108
Query: 98 ENINKLNIWVPSSDKYKESDGWPVLVYIHGGWLQYSSPYSEFFNTNEMFDDEEFTQKYIL 157
E+ LN++ ++ K PV+V+IHGG E++ + ++ +L
Sbjct: 109 EDCLYLNVY---TNNVKPDKARPVMVWIHGGGFIIGEANREWYGPDYFMKED-----VVL 160
Query: 158 VTPGYRLNMFGFLSGKELLEEDEASSNFGFWDQRLAIEWTYKYIKYFGGNPDKISVGGIS 217
VT YRL GF+S K E N G DQ LA++W FGG+P+ I+V G S
Sbjct: 161 VTIQYRLGALGFMSLKS--PELNVPGNAGLKDQVLALKWIKNNCASFGGDPNCITVFGES 218
Query: 218 AGAYSTFFQL 227
AG ST + +
Sbjct: 219 AGGASTHYMM 228
>7301005 [R] KOG1516 Carboxylesterase and related proteins
Length = 576
Score = 73.2 bits (178), Expect = 1e-12
Identities = 55/189 (29%), Positives = 90/189 (47%), Gaps = 23/189 (12%)
Query: 39 HRFAQIPYAEPFTKENRFKRPVPLADDFDYTG--DYKEFGLKCPQPSVPNPAFRYTKSPS 96
+ F + Y P T RF+ P + ++G D G CP ++ F+
Sbjct: 72 YSFKGMRYGAPPTGARRFRAAEP---EKPWSGIRDASREGQSCPHKNMILDTFK-----G 123
Query: 97 DENINKLNIW---VPSSDKYKESDGWPVLVYIHGGWLQYSSPYSEFFNTNEMFDDEEFTQ 153
DE+ +N++ +P D+ E PV+V++HGG + S S + + + ++
Sbjct: 124 DEDCLFVNVFTTQMPKDDESAEQPKLPVMVWLHGGGFSFGSGNSFLYGPDYLVAED---- 179
Query: 154 KYILVTPGYRLNMFGFLSGKELLEEDEASSNFGFWDQRLAIEWTYKYIKYFGGNPDKISV 213
+LVT YRL GFL+ +A N G DQ LA++W I FGG+P+++++
Sbjct: 180 -IVLVTLNYRLGPLGFLTAGP-----DAPGNQGLKDQVLALKWVRDNIAAFGGDPNQVTI 233
Query: 214 GGISAGAYS 222
G SAGA S
Sbjct: 234 FGESAGASS 242
>CE28763 [R] KOG1516 Carboxylesterase and related proteins
Length = 562
Score = 72.8 bits (177), Expect = 1e-12
Identities = 58/185 (31%), Positives = 88/185 (47%), Gaps = 22/185 (11%)
Query: 41 FAQIPYAEPFTKENRFKRPVPLADDFDYTGDYKEFGLKCPQPSVPNPAFRYT---KSPSD 97
F IP+A+P + RF++PV D ++ ++ C P +R S S
Sbjct: 38 FLAIPFAKPPVDDLRFEKPVA-PDPWEDVYPATQYRNDC------TPHYRLVAQFSSYSG 90
Query: 98 ENINKLNIWVPSSDKYKESDGWPVLVYIHGGWLQYSSPYSEFFNTNEMFDDEEFTQKYIL 157
E+ LNI P K+++ PVL +IHGG + S + E F +Q I+
Sbjct: 91 EDCLTLNIIKP-----KKAEKLPVLFWIHGGGYEIGSASQHGY---EFFAKRYASQGVIV 142
Query: 158 VTPGYRLNMFGFLSGKELLEEDEASSNFGFWDQRLAIEWTYKYIKYFGGNPDKISVGGIS 217
T YRL GF S + N+G +DQ A+E+ I+ FGG+P++I++ G S
Sbjct: 143 ATVQYRLGFMGFFSEGT----SDVQGNWGLFDQAAALEFVKSNIENFGGDPNQITIWGYS 198
Query: 218 AGAYS 222
AGA S
Sbjct: 199 AGAAS 203
>7300594 [R] KOG1516 Carboxylesterase and related proteins
Length = 537
Score = 72.4 bits (176), Expect = 2e-12
Identities = 58/203 (28%), Positives = 87/203 (42%), Gaps = 36/203 (17%)
Query: 41 FAQIPYAEPFTKENRFKRPVPLADDFDYTGDYKEFGLKCPQ--PSVPNPAFRYTKSPS-- 96
F +PYA P TK+NRF P +D ++ CPQ P++ N K P
Sbjct: 48 FLGVPYATPPTKQNRFS-PTRAPAPWDGIRISDKYSPVCPQRLPNIQNETAALEKMPKGR 106
Query: 97 --------------DENINKLNIWVPSSDKYKESDGWPVLVYIHGGWLQYSS--PYSEFF 140
E+ LN++ P + E PV+V+IHG ++SS PY
Sbjct: 107 LEYLKRLLPFLENQSEDCLYLNVFSPVNAGANEKK-LPVIVFIHGESFEWSSGNPY---- 161
Query: 141 NTNEMFDDEEFTQKY---ILVTPGYRLNMFGFLSGKELLEEDEASSNFGFWDQRLAIEWT 197
D Y ++VT YRL + GFL+ +N+G DQ A+ W
Sbjct: 162 -------DGSVLASYGEVVVVTLNYRLGILGFLNANPNPHAHARVANYGLMDQMAALHWI 214
Query: 198 YKYIKYFGGNPDKISVGGISAGA 220
+ I+ FGG+P+ +++ G GA
Sbjct: 215 QQNIQKFGGDPNSVTLAGHGTGA 237
>CE15485 [R] KOG1516 Carboxylesterase and related proteins
Length = 554
Score = 71.6 bits (174), Expect = 3e-12
Identities = 117/513 (22%), Positives = 209/513 (39%), Gaps = 102/513 (19%)
Query: 35 NVTTHRFAQIPYAEPFTKENRFKRPVPLADDFDYTGDYKEFGLKCPQPSVPNPAFRYTKS 94
N T+ F IP+ EP + RF++P P + ++ T + KEF C + V
Sbjct: 44 NQTSVVFLGIPHIEPPVGKLRFRKPKPYRNTWNNTLETKEFKPTCFRNFVA------ADG 97
Query: 95 PSDENINKLNIWVPSSDKYK-ESDGWPVLVYIHGGWLQYSSPYSEFFNTNEMFDDEEFTQ 153
+ E+ +N++ S+KY E+ V+V + G +Q + FFN + + +
Sbjct: 98 STSEDCLYINVY---SNKYCIENKNCSVMVVVPSGLVQ---SHGSFFNDTIINNFVGQNR 151
Query: 154 KYILVTPGYRLNMFGF--LSG--KELLEEDEASSNFGFWDQRLAIEWTYKYIKYFGGNPD 209
++VT YRL +FG L G K +LE+ N +D W + I FGG+
Sbjct: 152 NIVVVTVPYRLGIFGSPNLPGNVKNILEK-----NLMLYDVIEGCNWVDREIGNFGGDSS 206
Query: 210 KISVGGISAGAYSTFFQLAYELYHPEDNQIIKQALFFSNLVYVQPKTIEECQEQFDEIVE 269
KI+ G +GA T + L PE + Q + S +Y+Q KT + F ++V+
Sbjct: 207 KITYFGHRSGA--TIGAILSLL--PESENLFHQMILMSTPLYMQSKTANS--KSFLKVVK 260
Query: 270 KLDIDPKASGQEKLAVLRELDAPFIEDFIPTLTHHTFRAVTDDKF---ISSTLIKDLDSG 326
++ D + + +R++ A E+F+ T H+ +D I L++D
Sbjct: 261 QVGCDESIENVDIIECMRKVRA---ENFVDT--HNQLNEENEDSLNFVIDGVLLRD---- 311
Query: 327 EYARRLLSIKGDKFRILCGEVDNEPLKYSLLNTPQTLGELPVQVGNYYPKNIVDSLLDLY 386
RR+L K P +G +P +V L Y
Sbjct: 312 -EPRRILESGNFK------------------KIPLLIGTVPHEV-----------LYTRY 341
Query: 387 KVDKLNPASPTLKEDLRVAYGDIIGDGQVYASGRGYLHKLVEHGFPSKNIFRYRVSYRAK 446
+DK N +KE L + ++ G Y G++ + VE F + S A
Sbjct: 342 MIDKENGIK--MKELLELC--ELFGFVGAYEKPYGFVEQCVE--------FYMKNSTTAT 389
Query: 447 WLDNHIEPDDRVPHAGDFSLWFYCLREGYTDEERIHI---------NEWLQPYLQFLNFK 497
+LD++I F + L ++ E+ +++ +EW + + + +
Sbjct: 390 FLDDYI-----------FHVPTSYLARKHSSEKPVYLFVNYGAPYGDEWSKLNPKIMKYY 438
Query: 498 SLDSWDSDDVKKYRIFKEDGSFDYVDDIHWDWG 530
+D D ++ R + SF++ DD ++G
Sbjct: 439 DIDFNDKYEMAGMRYGFHEKSFEFWDDTAKEYG 471
>CE28363 [T] KOG4389 Acetylcholinesterase/Butyrylcholinesterase
Length = 629
Score = 70.1 bits (170), Expect = 8e-12
Identities = 59/209 (28%), Positives = 93/209 (44%), Gaps = 20/209 (9%)
Query: 41 FAQIPYAEPFTKENRFKRPVPLADDFDYTGDYKEFGLKC------PQPSVPNPAFRYTKS 94
F +PYA+P RFK + D + + + C P P
Sbjct: 63 FLGVPYAKPPIGSRRFKM-AEMIDRWSGELEARTLAKTCYLTIDSAFPQFPGAEMWNPPG 121
Query: 95 PSDENINKLNIWVPSSDKYKESDGWPVLVYIHGGWLQYSSPYSEFFNTNEMFDDEEFTQK 154
E+ +NIWVP ++ DG V+V+I+GG +P + ++ +F +E T
Sbjct: 122 AISEDCLNMNIWVP-----EDHDG-SVMVWIYGGGFFSGTPSLDLYS-GSVFAAKEHT-- 172
Query: 155 YILVTPGYRLNMFGFLSGKELLEEDEASSNFGFWDQRLAIEWTYKYIKYFGGNPDKISVG 214
I+V YRL FGFL ++ N G DQ+LA+ W ++ I FGG+ ++++
Sbjct: 173 -IVVNVNYRLGPFGFLY---FGDDSPIQGNMGLMDQQLALRWVHENIGAFGGDRSRVTLF 228
Query: 215 GISAGAYSTFFQLAYELYHPEDNQIIKQA 243
G SAG+ ST L H II ++
Sbjct: 229 GESAGSASTTAHLFAPNSHKYFRNIIAKS 257
>Hs9506787 [R] KOG1516 Carboxylesterase and related proteins
Length = 828
Score = 68.6 bits (166), Expect = 2e-11
Identities = 65/237 (27%), Positives = 94/237 (39%), Gaps = 51/237 (21%)
Query: 21 GTLTGYTFKSPRTNNVTTHRFAQIPYAEPFTKENRFKRPVPLADDFDYTGDYKEFGLKCP 80
G L G P ++ +PYA P E RF P P + + F CP
Sbjct: 49 GKLRGARVPLPSEILGPVDQYLGVPYAAPPIGEKRFLPPEP-PPSWSGIRNATHFPPVCP 107
Query: 81 Q------PSVPNPAF---------RYTKSPSDENINKLNIWVPSSD-------------- 111
Q P V P + Y + P+++ + LN++VP+ D
Sbjct: 108 QNIHTAVPEVMLPVWFTANLDIVATYIQEPNEDCLY-LNVYVPTEDGSGAKKQGEDLADN 166
Query: 112 ------KYKESDGWPVLVYIHGGWLQYSSPYSEFFNTNEMFDDEEFTQ--KYILVTPGYR 163
++S PV+VYIHGG S T M D I++T YR
Sbjct: 167 DGDEDEDIRDSGAKPVMVYIHGG--------SYMEGTGNMIDGSIPASYGNVIVITLNYR 218
Query: 164 LNMFGFLSGKELLEEDEASSNFGFWDQRLAIEWTYKYIKYFGGNPDKISVGGISAGA 220
+ + GFLS + A N+G DQ A+ W + I +FGG+P +I+V G GA
Sbjct: 219 VGVLGFLS----TGDQAAKGNYGLLDQIQALRWVSENIAFFGGDPRRITVFGSGIGA 271
>Hs4504565 [R] KOG1516 Carboxylesterase and related proteins
Length = 559
Score = 68.2 bits (165), Expect = 3e-11
Identities = 59/198 (29%), Positives = 87/198 (43%), Gaps = 26/198 (13%)
Query: 35 NVTTHRFAQIPYAEPFTKENRFKRPVPLADDFDYTGDYKEFGLKCPQPSVPNPA-----F 89
N F IP+A+P RF P P + + D C Q + F
Sbjct: 52 NAGVQTFLGIPFAKPPLGPLRFAPPEP-PESWSGVRDGTTHPAMCLQDLTAVESEFLSQF 110
Query: 90 RYTKSPSD---ENINKLNIWVPSSDKYKESDGWPVLVYIHGGWLQYSSPYSEFFNTNEMF 146
T PSD E+ L+I+ P+ E PV+V+IHGG L F ++
Sbjct: 111 NMT-FPSDSMSEDCLYLSIYTPAHSH--EGSNLPVMVWIHGGAL--------VFGMASLY 159
Query: 147 DDEEFT--QKYILVTPGYRLNMFGFLSGKELLEEDEASSNFGFWDQRLAIEWTYKYIKYF 204
D + ++V YRL + GF S + A+ N+G+ DQ A+ W + I +F
Sbjct: 160 DGSMLAALENVVVVIIQYRLGVLGFFS----TGDKHATGNWGYLDQVAALRWVQQNIAHF 215
Query: 205 GGNPDKISVGGISAGAYS 222
GGNPD++++ G SAG S
Sbjct: 216 GGNPDRVTIFGESAGGTS 233
>CE13028 [R] KOG1516 Carboxylesterase and related proteins
Length = 656
Score = 68.2 bits (165), Expect = 3e-11
Identities = 56/189 (29%), Positives = 84/189 (43%), Gaps = 14/189 (7%)
Query: 35 NVTTHRFAQIPYAEPFTKENRFKRPVPLADDFDYTGDYKEFGLKCPQPSVPNPAFRYTKS 94
N + F IPY EP + RF++P P + + K+F C S
Sbjct: 42 NQSAIAFLGIPYVEPPIGDLRFRKPRP-QKTWSGVLETKKFKPACMSNSTKTYKNGGIGG 100
Query: 95 PSDENINKLNIWVPSSDKYKESDGWPVLVYIHGGWLQYSSPYS---EFFNTNEMFDDEEF 151
P E+ LN+ ++ E+ V++ +HGG + S + E N + D
Sbjct: 101 PISEDCLYLNVL--TNQYCLENKNCSVVIIVHGGGYLFESAATFNHEILVNNFVGQDRNI 158
Query: 152 TQKYILVTPGYRLNMFGFLSGKELLEEDEASSNFGFWDQRLAIEWTYKYIKYFGGNPDKI 211
++VT YRL +FGF L E N G +D A++W + IK FGGN D+I
Sbjct: 159 ----VVVTINYRLGIFGFGH----LNGFEGDKNVGIFDTLEAVKWVRREIKQFGGNKDRI 210
Query: 212 SVGGISAGA 220
++ G SAGA
Sbjct: 211 TLAGHSAGA 219
>7298793 [R] KOG1516 Carboxylesterase and related proteins
Length = 565
Score = 68.2 bits (165), Expect = 3e-11
Identities = 56/186 (30%), Positives = 85/186 (45%), Gaps = 24/186 (12%)
Query: 41 FAQIPYAEPFTKENRFKRPVPLADDFDYTGDYKEFGLK-CPQPSVPNPAFRYTKS--PSD 97
F IP+A+P E RF+ P P + G++ C P + S
Sbjct: 59 FEGIPFAQPPVGELRFRAPQP---------PHPWLGVRDCTYPRAKPMQKHFVLSIVEGS 109
Query: 98 ENINKLNIWVPSSDKYKESDGWPVLVYIHGGWLQYSSPYSEFFNTNEMFDDEEFTQKYIL 157
E+ LN++ S + + PV+V+I+GG Q+ +F++ D Q ++
Sbjct: 110 EDCLYLNVY---SKRLRSDKPLPVIVWIYGGGFQFGEAGRDFYSP-----DYFMQQDVVV 161
Query: 158 VTPGYRLNMFGFLSGKELLEED-EASSNFGFWDQRLAIEWTYKYIKYFGGNPDKISVGGI 216
VT YR+ GFLS L + D + N G DQ +A+ W + I F G+P I+V G
Sbjct: 162 VTFNYRVGALGFLS---LADRDLDVPGNAGLKDQVMALRWISQNIAQFNGDPQNITVMGE 218
Query: 217 SAGAYS 222
SAGA S
Sbjct: 219 SAGAAS 224
>CE22953 [R] KOG1516 Carboxylesterase and related proteins
Length = 550
Score = 67.8 bits (164), Expect = 4e-11
Identities = 74/275 (26%), Positives = 109/275 (38%), Gaps = 27/275 (9%)
Query: 1 MGQVVSTEGTTPFPISIPGQGTLTGYTFKSPRTNNVTTHR-------FAQIPYAEPFTKE 53
MG VS T +P P + LT Y P H F IPYA P
Sbjct: 1 MGGTVSKHTTPHYP---PSRQVLTSY---GPIEGRRLIHEGEKQVDAFQGIPYAAPPIGN 54
Query: 54 NRFKRPVPLADDFDYTGDYKEFGLKCPQPS-VPNPAFRYTKSPSDENINKLNIWVPSSDK 112
RF P P + + + K FG + Q V +P SP E+ LNI+ P
Sbjct: 55 LRFALPQP-HEKWTEVRETKSFGARGIQKDHVLSPK----TSPQSEDNLTLNIFTPVWTP 109
Query: 113 YKESDGWPVLVYIHGGWLQYSSPYSEFFNTNEMFDDEEFTQKYILVTPGYRLNMFGFLSG 172
E+ G+PV++YIHGG S + + T+ ++VT YRL GF +
Sbjct: 110 KNET-GFPVILYIHGGGFVSDSAHKY---GDMSICQHLVTKDVVVVTIQYRLGFLGFWT- 164
Query: 173 KELLEEDEASSNFGFWDQRLAIEWTYKYIKYFGGNPDKISVGGISAGAYSTFFQLAYELY 232
+ N D A++W + I F G+P+ I++ G SAG S F +
Sbjct: 165 ---TGDSSIPDNVALHDMVFALKWVKENIGLFNGDPNNITLMGQSAGGASVDFLSISPVS 221
Query: 233 HPEDNQIIKQALFFSNLVYVQPKTIEECQEQFDEI 267
++I S + P+ + C+ + EI
Sbjct: 222 RDLFQKVIPMGGNASCSWAIHPRPLNACRNRAQEI 256
>CE09404 [R] KOG1516 Carboxylesterase and related proteins
Length = 583
Score = 67.8 bits (164), Expect = 4e-11
Identities = 62/224 (27%), Positives = 93/224 (40%), Gaps = 39/224 (17%)
Query: 21 GTLTGYTFKSPRTNNVTTHRFAQIPYAEPFTKENRFKRPVPLADDFDYTGDYKEFGLKCP 80
G + G+ K V F IP+A+ + RFK P +D+D FG + P
Sbjct: 29 GLVEGFRIKIDDDREVDM--FLGIPFAKAPVGDLRFKNPEH-TEDWDGVKKCVRFGPRAP 85
Query: 81 QPSVPNPAFRYTKSPSDENINKLNIWVPSSDKYKESDG----------------WPVLVY 124
Q F S++ + LN++ P+ + S+G PV+VY
Sbjct: 86 QADFFWERFTLGVGKSEDCLY-LNVFSPTWKAEEVSNGVGFFKPICGKIELFQLHPVMVY 144
Query: 125 IHGGWLQYSSPYSEFFNTNEMFDDEEFTQKY------ILVTPGYRLNMFGFLSGKELLEE 178
+HGG S + DE KY ++VT YRL + GF S + +
Sbjct: 145 VHGGGFLIDSAVK--------YGDEGIA-KYLCRHGVVVVTIQYRLGLLGFFSTGDQV-- 193
Query: 179 DEASSNFGFWDQRLAIEWTYKYIKYFGGNPDKISVGGISAGAYS 222
N G WD +A++W + FGG+P K++V G SAG S
Sbjct: 194 --CPGNLGLWDMTMALQWVRDNVHAFGGDPRKVTVFGQSAGGVS 235
>7296447 [R] KOG1516 Carboxylesterase and related proteins
Length = 559
Score = 67.4 bits (163), Expect = 5e-11
Identities = 60/204 (29%), Positives = 98/204 (47%), Gaps = 25/204 (12%)
Query: 19 GQGTLTGYTFKSPRTNNVTTHRFAQIPYAEPFTKENRFKRPVPLADDFDYTGDYK--EFG 76
GQGT+ G + T+ +F IP+AEP +E RF+ PV + +TG FG
Sbjct: 49 GQGTVLGNYAYTAWTDRAFM-QFRGIPFAEPPIEELRFRPPVARSP---WTGTLNALNFG 104
Query: 77 LKCPQPSVPNPAFRYTKSPSDENINKLNIWVPSSDKYKESDGWPVLVYIHGGWLQYSSPY 136
+CP + N + + + ++ + L+++ + S PV+ YI+GG S
Sbjct: 105 QRCPV--ITNLDSQMSDAELEDCLT-LSVYTKNL-----SASQPVMFYIYGGGFYNGS-- 154
Query: 137 SEFFNTNEMFDDEEFTQKYILVTPGYRLNMFGFLSGKELLEEDEASSNFGFWDQRLAIEW 196
SE N + + + +LV P YR+ G+LS +E N D +A++W
Sbjct: 155 SEDHPPNYLLEKD-----VVLVVPQYRVGALGWLS----TYTEELPGNAPIADILMALDW 205
Query: 197 TYKYIKYFGGNPDKISVGGISAGA 220
+I FGG+P K+++ G SAGA
Sbjct: 206 VQMHISSFGGDPQKVTIFGQSAGA 229
>Hs6912298 [R] KOG1516 Carboxylesterase and related proteins
Length = 567
Score = 66.6 bits (161), Expect = 9e-11
Identities = 57/207 (27%), Positives = 91/207 (43%), Gaps = 29/207 (14%)
Query: 41 FAQIPYAEPFTKENRFKRPVPLADDFDYTGDYKEFGLKCPQPSVPNPAFRYTKSPSDENI 100
F +P+A+P RF P P A+ + + + + C Q +V + ENI
Sbjct: 50 FLGVPFAKPPLGSLRFAPPQP-AEPWSFVKNTTSYPPMCSQDAVGWQVLSELFTNRKENI 108
Query: 101 NK--------LNIWVPSSDKYKESDGWPVLVYIHGGWLQYSSPYSEFFNTNEMFDDEEFT 152
LNI+ P+ ++ PV+V+IHGG L + +D +
Sbjct: 109 PLQFSEDCLYLNIYTPAD--LTKNSRLPVMVWIHGGGLVVGGAST--------YDGLALS 158
Query: 153 --QKYILVTPGYRLNMFGFLSGKELLEEDEASSNFGFWDQRLAIEWTYKYIKYFGGNPDK 210
+ ++VT YRL ++GF S ++ + N+G DQ A+ W I FGGNP
Sbjct: 159 AHENVVVVTIQYRLGIWGFFS----TGDEHSRGNWGHLDQVAALRWVQDNIANFGGNPGS 214
Query: 211 ISVGGISAGAYS----TFFQLAYELYH 233
+++ G SAG +S LA L+H
Sbjct: 215 VTIFGESAGGFSVSVLVLSPLAKNLFH 241
>CE17255 [R] KOG1516 Carboxylesterase and related proteins
Length = 583
Score = 66.6 bits (161), Expect = 9e-11
Identities = 54/184 (29%), Positives = 93/184 (50%), Gaps = 18/184 (9%)
Query: 41 FAQIPYAEPFTKENRFKRPVPLADDFDYTGDYKEFGLKCPQPSVPNPAFRYTKSPS---D 97
F +IP+A+P + RF++P+ A+ ++ + E+G C S + KSP D
Sbjct: 44 FKKIPFAKPPIGKLRFQKPMA-AEKWEGILNATEYGPACMSNSSTS------KSPQKWID 96
Query: 98 ENINKLNIWVPSSDKYKESDGWPVLVYIHGGWLQYSSPYSEFFNTNEMFDDEEFTQKYIL 157
E+ +NI+ ++D S V+ Y+HGG L Y S + F +FD ++ IL
Sbjct: 97 EDCLHINIF--TTDTCLSSKNCSVVFYVHGGELVYDS--AVMFEDKYLFDTFS-SRDVIL 151
Query: 158 VTPGYRLNMFGFLSGKELLEEDEASSNFGFWDQRLAIEWTYKYIKYFGGNPDKISVGGIS 217
V P +RL +F ++ ++ A +N +D LA+E+ I FGG+ D+++ G S
Sbjct: 152 VIPAFRLGLFSHFVVED---QNVAPNNLALYDILLALEFVKSEIHNFGGSSDRVTAFGHS 208
Query: 218 AGAY 221
G +
Sbjct: 209 YGGH 212
>CE29456 [R] KOG1516 Carboxylesterase and related proteins
Length = 482
Score = 65.5 bits (158), Expect = 2e-10
Identities = 73/276 (26%), Positives = 115/276 (41%), Gaps = 28/276 (10%)
Query: 5 VSTEGTTPFPISIPGQGTLTGYTFKSPRTNNVTTHRFAQIPYAEPFTKENRFKRPVPLAD 64
+ST +PF + + G + G T+ F IP+A P RF+ P A
Sbjct: 18 ISTRHISPFELRV-NSGAIRGERLL---TDGQDYSVFKGIPFAMPPVGYLRFQMPKEPAK 73
Query: 65 DFDYTGDYKEFGLKCPQPSVPNPAF---RYTKSPSDENINKLNIWVPSSDKYKESDGWPV 121
+ + ++ C Q N A RY S++ + LN++ P+ +Y +D +PV
Sbjct: 74 -WRGVMNATQYSAMCMQNIDENDAGEPERYVAHVSEDCLY-LNVFSPTPYQYT-NDTYPV 130
Query: 122 LVYIHGGWLQYSSPYSEFFNTNEMFDDEEFTQKYILVTPGYRLNMFGFLS-GKELLEEDE 180
+V+IHGG Q S ++K + VT YRL GF S G +L
Sbjct: 131 IVFIHGGRFQTGSGSDI---PQRAILSNFVSRKIVFVTFNYRLGPLGFASTGDSVLP--- 184
Query: 181 ASSNFGFWDQRLAIEWTYKYIKYFGGNPDKISVGGISAGAYSTFFQLAYELYHPEDNQII 240
N G WDQ A++W + FGG+P I + G GA S + P +
Sbjct: 185 --GNIGLWDQIWALKWVKANAEVFGGDPSNILLMGHGTGAASA----SLLALSPRAEGLF 238
Query: 241 KQALFFSNLVYVQPKTIEECQ----EQFDEIVEKLD 272
++ L S +QP + Q + ++E V +D
Sbjct: 239 QKVLLMSGSA-LQPGVVRNTQRLHFDDYEEFVPIID 273
>7294606 [R] KOG1516 Carboxylesterase and related proteins
Length = 544
Score = 64.3 bits (155), Expect = 4e-10
Identities = 54/199 (27%), Positives = 89/199 (44%), Gaps = 19/199 (9%)
Query: 34 NNVTTHRFAQIPYAEPFTKENRFKRPVPLADDFDYTGDYKEFGLKCPQPSVPNPAFRYTK 93
+N + + IP AE T RF+ P P + + + + ++C Q + K
Sbjct: 38 DNGLYYSYESIPNAEHPTGALRFEAPQPYSHHWTDVFNATQSPVECMQWN--QFINENNK 95
Query: 94 SPSDENINKLNIWVPSSDKYKESDGWPVLVYIHGGWLQYSSPYSEFFNTNEMFDDEEFTQ 153
DE+ ++I+ P K +PV+V +HGG + F + ++ + +
Sbjct: 96 LMGDEDCLTVSIYKP---KKPNRSSFPVVVLLHGG--------AFMFGSGSIYGHDSIMR 144
Query: 154 K--YILVTPGYRLNMFGFLSGKELLEEDEASSNFGFWDQRLAIEWTYKYIKYFGGNPDKI 211
+ ++V + L GF S + N+G DQRLA++W K I +FGG PD I
Sbjct: 145 EGTLLVVKISFGLGPLGFAS----TGDRHLPGNYGLKDQRLALQWIKKNIAHFGGMPDNI 200
Query: 212 SVGGISAGAYSTFFQLAYE 230
+ G SAG S QL +E
Sbjct: 201 VLIGHSAGGASAHLQLLHE 219
>7291429 [R] KOG1516 Carboxylesterase and related proteins
Length = 566
Score = 64.3 bits (155), Expect = 4e-10
Identities = 57/197 (28%), Positives = 86/197 (42%), Gaps = 26/197 (13%)
Query: 39 HRFAQIPYAEPFTKENRFKRPVPLAD-----DFDYTGDYKEFGLKCPQPSVPNPAFRYTK 93
+ F IP+A+P E RF+ P P + D Y + + S+ N A
Sbjct: 57 YSFEGIPFAQPPVGELRFRAPQPPSSWQGVRDCTYAREKP-----MQRNSITNAA----- 106
Query: 94 SPSDENINKLNIWVPSSDKYKESDGWPVLVYIHGGWLQYSSPYSEFFNTNEMFDDEEFTQ 153
E+ LN++ + K PV+V+I GG Q E + + +
Sbjct: 107 -EGSEDCLYLNVYAKRLESPKPL---PVMVWIFGGGFQVGGASRELYGPDYFMKHD---- 158
Query: 154 KYILVTPGYRLNMFGFLSGKELLEEDEASSNFGFWDQRLAIEWTYKYIKYFGGNPDKISV 213
+LVT YR+ + GFLS K+ +E + N G DQ A+ W + I F G+P+ I+V
Sbjct: 159 -ILLVTINYRVGVLGFLSLKD--KELKIPGNAGLKDQIQALRWVKENIASFNGDPESITV 215
Query: 214 GGISAGAYSTFFQLAYE 230
G SAG ST + E
Sbjct: 216 FGESAGGASTHILMQTE 232
>7298805 [R] KOG1516 Carboxylesterase and related proteins
Length = 554
Score = 63.9 bits (154), Expect = 6e-10
Identities = 51/193 (26%), Positives = 88/193 (45%), Gaps = 16/193 (8%)
Query: 41 FAQIPYAEPFTKENRFKRPVPLADDFDYTGDYKEFGLKCPQPSVPNPAFRYTKSPSDENI 100
F +IP+A+P E R+K P P + + + + P+P + F T E+
Sbjct: 42 FERIPFAKPPVGELRYKAPQPP----EVWTEVRSCTSQGPKPLQKHFVFEMTDG--SEDC 95
Query: 101 NKLNIWVPSSDKYKESDGWPVLVYIHGGWLQYSSPYSEFFNTNEMFDDEEFTQKYILVTP 160
LN++ + K PV+V+I+GG Q+ E ++ + + ++ ++++
Sbjct: 96 LYLNVYTKNLYPTKPM---PVMVWIYGGGFQFGEASRECYSPDYLLRED-----VVVISI 147
Query: 161 GYRLNMFGFLSGKELLEEDEASSNFGFWDQRLAIEWTYKYIKYFGGNPDKISVGGISAGA 220
YRL GFL + E + N G DQ LA+ W FGG+ I++ G SAG+
Sbjct: 148 NYRLGPLGFLCLDD--PELDVPGNAGLKDQVLALRWVKANCSRFGGDSANITIFGDSAGS 205
Query: 221 YSTFFQLAYELYH 233
S + + E H
Sbjct: 206 ASVHYMMITEQTH 218
>Hs21450749 [R] KOG1516 Carboxylesterase and related proteins
Length = 525
Score = 63.2 bits (152), Expect = 1e-09
Identities = 56/193 (29%), Positives = 85/193 (44%), Gaps = 19/193 (9%)
Query: 36 VTTHRFAQIPYAEPFTKENRFKRPVPLADDFDYTGDYKEFGLKCPQPSV------PNPAF 89
V + F +P+A P RF P P A +D + + C Q S
Sbjct: 52 VPVNVFLGVPFAAPPLGSLRFTNPQP-ASPWDNLREATSYPNLCLQNSEWLLLDQHMLKV 110
Query: 90 RYTKSPSDENINKLNIWVPSSDKYKESDGWPVLVYIHGGWLQYSSPYSEFFNTNEMFDDE 149
Y K E+ LNI+ P+ PVLV+ GG + S + F+ + + E
Sbjct: 111 HYPKFGVSEDCLYLNIYAPAHAD--TGSKLPVLVWFPGGAFKTGS--ASIFDGSALAAYE 166
Query: 150 EFTQKYILVTPGYRLNMFGFLSGKELLEEDEASSNFGFWDQRLAIEWTYKYIKYFGGNPD 209
+ ++V YRL +FGF + + A N+ F DQ A+ W K I++FGG+P
Sbjct: 167 DV----LVVVVQYRLGIFGFFT----TWDQHAPGNWAFKDQVAALSWVQKNIEFFGGDPS 218
Query: 210 KISVGGISAGAYS 222
+++ G SAGA S
Sbjct: 219 SVTIFGESAGAIS 231
>CE15197 [R] KOG1516 Carboxylesterase and related proteins
Length = 673
Score = 63.2 bits (152), Expect = 1e-09
Identities = 57/204 (27%), Positives = 93/204 (44%), Gaps = 17/204 (8%)
Query: 21 GTLTGYTFKSPRT--NNVTTHRFAQIPYAEPFTKENRFKRPVPLA--DDFDYTGDYKEFG 76
GT+ G S + N T F IP+ EP RF++P P D T +YK
Sbjct: 26 GTIEGKILTSTYSPLGNHTGIGFLGIPFVEPPAGNLRFRKPRPPIPWDGILETKEYKPAC 85
Query: 77 LKCPQPSVPNPAFRYTKSPSDENINKLNIWVPSSDKYKESDGWPVLVYIHGGWLQYSSPY 136
+ + + N P E+ N++ ++ + V++ +HGG + S
Sbjct: 86 MSDAKKTYKNGV----GGPISEDCLYANVF--TNQYCMKRKNCSVMIVVHGGRILTES-- 137
Query: 137 SEFFNTNEMFDDEEFT-QKYILVTPGYRLNMFGFLSGKELLEEDEASSNFGFWDQRLAIE 195
+ FN + ++ + ++VT YRL FGF +L ++ SN G +D A++
Sbjct: 138 ASAFNPEILVNNFVGQGRNIVVVTFNYRLGTFGF----GVLNGEKGDSNVGMFDMLEAVK 193
Query: 196 WTYKYIKYFGGNPDKISVGGISAG 219
WT K + FGGN DK+++ G SAG
Sbjct: 194 WTRKEVHNFGGNKDKLTMVGHSAG 217
>Hs16905524 [R] KOG1516 Carboxylesterase and related proteins
Length = 566
Score = 62.4 bits (150), Expect = 2e-09
Identities = 56/207 (27%), Positives = 87/207 (41%), Gaps = 29/207 (14%)
Query: 41 FAQIPYAEPFTKENRFKRPVPLADDFDYTGDYKEFGLKCPQPSVPNPAFRYTKSPSDENI 100
F IP+ +P RF P P A+ + + + + C Q + ENI
Sbjct: 50 FLGIPFGKPPLGPLRFTPPQP-AEPWSFVKNATSYPPMCTQDPKAGQLLSELFTNRKENI 108
Query: 101 NK--------LNIWVPSSDKYKESDGWPVLVYIHGGWLQYSSPYSEFFNTNEMFDDEEFT 152
LNI+ P+ + + PV+V+IHGG L + + +D
Sbjct: 109 PLKLSEDCLYLNIYTPAD--LTKKNRLPVMVWIHGGGLMVGAAST--------YDGLALA 158
Query: 153 --QKYILVTPGYRLNMFGFLSGKELLEEDEASSNFGFWDQRLAIEWTYKYIKYFGGNPDK 210
+ ++VT YRL ++GF S ++ + N+G DQ A+ W I FGGNP
Sbjct: 159 AHENVVVVTIQYRLGIWGFFS----TGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGS 214
Query: 211 ISVGGISAGAYS----TFFQLAYELYH 233
+++ G SAG S LA L+H
Sbjct: 215 VTIFGESAGGESVSVLVLSPLAKNLFH 241
>CE15193 [R] KOG1516 Carboxylesterase and related proteins
Length = 606
Score = 61.6 bits (148), Expect = 3e-09
Identities = 58/207 (28%), Positives = 91/207 (43%), Gaps = 21/207 (10%)
Query: 21 GTLTGYTFKSPRT--NNVTTHRFAQIPYAEPFTKENRFKRPVPLA--DDFDYTGDYKEFG 76
GT+ G + + N T F IPY EP E RF++P L + T DYK
Sbjct: 25 GTIEGKILNATYSPFGNQTATVFLGIPYVEPPIGELRFRKPRLLKSWEGVLETKDYKPAC 84
Query: 77 LKCPQPSVPNPAFRYTKSPSDENINKLNIWVPSSDKYKESDGWPVLVYIHGGWLQYSSPY 136
+ + + N E+ N++ ++ ++ V++ +HGG L S
Sbjct: 85 MSYWRKTFKNGFV----GEISEDCLYANVF--TNQYCLQNKNCSVMIVVHGGRLVCESGS 138
Query: 137 S---EFFNTNEMFDDEEFTQKYILVTPGYRLNMFGFLSGKELLEEDEASSNFGFWDQRLA 193
+ E F N + D ++VT YRL +FGF + + +N +D A
Sbjct: 139 AFKPEIFINNFVGQDRNI----VVVTFNYRLGVFGF----GVFNGETGDTNVAMYDMLEA 190
Query: 194 IEWTYKYIKYFGGNPDKISVGGISAGA 220
++W K I FGGN D+I++ G SAGA
Sbjct: 191 VKWVRKEIDQFGGNKDRITMAGHSAGA 217
>7298795 [R] KOG1516 Carboxylesterase and related proteins
Length = 551
Score = 61.6 bits (148), Expect = 3e-09
Identities = 56/213 (26%), Positives = 92/213 (42%), Gaps = 26/213 (12%)
Query: 41 FAQIPYAEPFTKENRFKRPVPLADDFDYTGDYKEFGLKCPQPSVPNPAFRYTKSPSD--E 98
F +IPYA+P RF P+P+ + L C +P F + + E
Sbjct: 37 FERIPYAQPPVGHLRFMAPLPV--------EPWSQPLDCTKPGQKPLQFNHYSKQLEGVE 88
Query: 99 NINKLNIWVPSSDKYKESDGWPVLVYIHGGWLQYSSPYSEFFNTNEMFDDEEFTQK-YIL 157
+ LN++ D + P++V+ GG + P T E+ + F + ++
Sbjct: 89 DCLYLNVYAKELDSPRPL---PLIVFFFGGGFEKGDP------TKELHSPDYFMMRDVVV 139
Query: 158 VTPGYRLNMFGFLSGKELLEEDEASSNFGFWDQRLAIEWTYKYIKYFGGNPDKISVGGIS 217
VT YR+ GFLS + N G DQ LA+EW + + F G+P ++ G S
Sbjct: 140 VTVSYRVGPLGFLSLND--PAVGVPGNAGLKDQLLAMEWIKENAERFNGDPKNVTAFGES 197
Query: 218 AGAYSTFFQLAYELYHPEDNQIIKQALFFSNLV 250
AGA S + Y + +P+ + +A+ S V
Sbjct: 198 AGAAS----VHYLMLNPKAEGLFHKAILQSGNV 226
>CE26855 [R] KOG1516 Carboxylesterase and related proteins
Length = 624
Score = 61.2 bits (147), Expect = 4e-09
Identities = 67/237 (28%), Positives = 114/237 (47%), Gaps = 27/237 (11%)
Query: 41 FAQIPYAEPFTKENRFKRPVPLADDFDYTGDYKEFGLKCPQPSVPNPAFRYTKSPS---D 97
F +IP+A+P RF++P A+ ++ + E+G C S +T+SP D
Sbjct: 42 FRRIPFAKPPIGTLRFQKP-ESAEKWNGVWNATEYGPACMSNST------WTQSPQKWVD 94
Query: 98 ENINKLNIWVPSSDK----YKESDGWPVLVYIHGGWLQYSSPYSEFFNTNEMFDDEEFT- 152
E+ +NI+ +SDK + + +VYIHGG + + S N+ F E F
Sbjct: 95 EDCLHVNIF--TSDKCLVRFDQILRIYFVVYIHGGEIVFDSAVM----FNDTFLLESFVK 148
Query: 153 QKYILVTPGYRLNMFGFLSGKELLEEDEASSNFGFWDQRLAIEWTYKYIKYFGGNPDKIS 212
Q ILV P +RL +F + + +++ A +N +D LA E+ I FGG+ KI+
Sbjct: 149 QDVILVIPAFRLGIFSHFT---VHDQNIAPNNLALYDIILAQEFVKSEIHNFGGDIQKIT 205
Query: 213 VGGISAGAYSTFFQLAYELYHPEDNQIIKQALFFSNLVYVQPKTIEECQEQFDEIVE 269
+ G S G + +A+ +D + ++ + S Y T+EE E+ D +V+
Sbjct: 206 LFGHSYGG-TIASMMAFSSEINQDLSLFQRIIVMSANQYFD--TLEEQIERSDRVVK 259
>CE16865 [R] KOG1516 Carboxylesterase and related proteins
Length = 592
Score = 60.8 bits (146), Expect = 5e-09
Identities = 56/186 (30%), Positives = 84/186 (45%), Gaps = 22/186 (11%)
Query: 39 HRFAQIPYAEPFTKENRFKRPVPLADDFDYTGDYKEFGLKCPQPSVPNPAFRYTKSPS-- 96
H F IP A+P + RF++P P + + + K +G C S + SP
Sbjct: 45 HLFKHIPLAKPPIGKLRFQKPEP-PEKWTGVRNAKAYGPACISNS------SVSTSPQKW 97
Query: 97 -DENINKLNIWVPSSDKYKESDGWPVLVYIHGGWLQYSSPYSEFFNTNEMFDDEEFTQKY 155
DE+ +NI+ +SDK +S V+ Y HGG L Y S + FN + Q
Sbjct: 98 IDEDCLHINIF--TSDKCLKSKDCAVVTYFHGGGLMYDS--AVMFNDTYLL-GTFVNQDV 152
Query: 156 ILVTPGYRLNMFGFLSGKELLEEDE--ASSNFGFWDQRLAIEWTYKYIKYFGGNPDKISV 213
I+ P +RL +F + ED+ A +N +D L +E+ I FGGN K ++
Sbjct: 153 IIAIPAFRLGIF-----SHFVVEDQSIAPTNLALYDILLGVEFVKNEIHNFGGNNQKNTI 207
Query: 214 GGISAG 219
G S G
Sbjct: 208 MGHSYG 213
>CE09114 [R] KOG1516 Carboxylesterase and related proteins
Length = 533
Score = 60.8 bits (146), Expect = 5e-09
Identities = 58/219 (26%), Positives = 98/219 (44%), Gaps = 30/219 (13%)
Query: 13 FPISIPGQGTL-TGYTFKSPRTNNVTTHRFAQIPYAEPFTKENRFKRPVPLADDFDYTGD 71
F ++ GQ + T Y +T NV H F +P+A+P + RF P ++T
Sbjct: 28 FTLNGSGQRIISTTYGKLEGKTVNVDQHMFKNVPFAKPPLGKLRFSLP-------EWTNP 80
Query: 72 YK------EFGLKCPQPSVPNPAFRYTKS--PSDENINKLNIWVPSSDKYKESDGWPVLV 123
+K E+ C N + R + P E+ LN++ +++ +S +V
Sbjct: 81 WKNIRNATEYSPSC----FSNSSMRTDSNFFPMSEDCLYLNVF--TNEYCLKSKNCSTVV 134
Query: 124 YIHGGWLQYSSPYSEFFNTNEMFDDEEFTQKYIL-VTPGYRLNMFGFLSGKELLEEDEAS 182
Y HGG + S N+ F E + ++ ++ + P YRL +FG L +
Sbjct: 135 YYHGGGINMDSAVQ----FNDTFILERYVKENVVFIIPAYRLGIFGLLY---FGSNNLVP 187
Query: 183 SNFGFWDQRLAIEWTYKYIKYFGGNPDKISVGGISAGAY 221
N D LA+ + ++ I FGG+ D I++ G SAGA+
Sbjct: 188 QNLAIHDCELALRFIHQEISNFGGHKDDINLMGHSAGAH 226
>CE18745 [R] KOG1516 Carboxylesterase and related proteins
Length = 552
Score = 60.5 bits (145), Expect = 6e-09
Identities = 39/133 (29%), Positives = 64/133 (47%), Gaps = 22/133 (16%)
Query: 96 SDENINKLNIWVP--SSDKYKESDGWPVLVYIHGGWL------QYSSPYSEFFNTNEMFD 147
S E+ +N++ P S ++ PV VYIHGG + Y N +
Sbjct: 91 SHEDCLFINVYTPNVSLGNVTQASKLPVYVYIHGGGFVEGGGNMGAGIYPNLVNKGPI-- 148
Query: 148 DEEFTQKYILVTPGYRLNMFGFLSGKELLEEDEASSNFGFWDQRLAIEWTYKYIKYFGGN 207
++V+ YRL FGF S +++ A N+ D A+ W +YI +FGG+
Sbjct: 149 --------VMVSINYRLGPFGFFSTRQMT----APGNWAISDWIEALNWVQRYISFFGGD 196
Query: 208 PDKISVGGISAGA 220
P+++++GG S+GA
Sbjct: 197 PNRVTIGGQSSGA 209
>7298794 [R] KOG1516 Carboxylesterase and related proteins
Length = 554
Score = 60.1 bits (144), Expect = 8e-09
Identities = 54/195 (27%), Positives = 88/195 (44%), Gaps = 26/195 (13%)
Query: 41 FAQIPYAEPFTKENRFKRPVPLADDFDYTGDYKEFGLKCP----QPSVPNPAFRYTKSPS 96
F IPYA+P + RF+ P P + + L C +P N +
Sbjct: 47 FEGIPYAKPPVGDLRFRAPQP--------PEPWQGVLNCTTNRSKPMQRNMLLGIVEG-- 96
Query: 97 DENINKLNIWVPSSDKYKESDGWPVLVYIHGGWLQYSSPYSEFFNTNEMFDDEEFTQK-Y 155
E+ LN++V + K PV+V+I+GG Q + +++ + F +K
Sbjct: 97 SEDCLHLNVYVKA---LKSEKPLPVIVWIYGGGFQKGEA------SRDIYSPDYFMKKPV 147
Query: 156 ILVTPGYRLNMFGFLSGKELLEEDEASSNFGFWDQRLAIEWTYKYIKYFGGNPDKISVGG 215
+ V YRL GFLS K+ + + N G DQ +A+ W + I +F G+P+ I++ G
Sbjct: 148 VFVAINYRLAALGFLSLKD--PKLDVPGNAGLKDQVMALRWISQNIAHFNGDPNNITLMG 205
Query: 216 ISAGAYSTFFQLAYE 230
SAG+ S + E
Sbjct: 206 ESAGSASVHVMMTTE 220
>CE27775 [R] KOG1516 Carboxylesterase and related proteins
Length = 673
Score = 59.3 bits (142), Expect = 1e-08
Identities = 55/206 (26%), Positives = 92/206 (43%), Gaps = 19/206 (9%)
Query: 21 GTLTGYTFK---SPRTNNVTTHRFAQIPYAEPFTKENRFKRPVPLA--DDFDYTGDYKEF 75
GT+ G SP N T F IP+ EP + R+++P P + T +YK
Sbjct: 24 GTIEGKILNISYSPLGNQSATV-FLGIPFVEPPIGDLRYRKPRPPKSWEGVLVTNEYKSA 82
Query: 76 GLKCPQPSVPNPAFRYTKSPSDENINKLNIWVPSSDKYKESDGWPVLVYIHGGWLQYSSP 135
+ + N P E+ LN+ +++ E+ V++ +HGG Y +
Sbjct: 83 CMSNATKTYKNKF----GGPISEDCLYLNVL--TNEYCLENKNCSVMMIVHGGG--YLTE 134
Query: 136 YSEFFNTNEMFDDEEFT-QKYILVTPGYRLNMFGFLSGKELLEEDEASSNFGFWDQRLAI 194
+ FN + ++ + ++VT YRL +F F D NFG +D ++
Sbjct: 135 SASTFNPEILINNFVGQGRNIVVVTFNYRLGLFSFGQ----FNGDRGDKNFGLYDMIESV 190
Query: 195 EWTYKYIKYFGGNPDKISVGGISAGA 220
W + I+ FGGN ++I++ G SAGA
Sbjct: 191 NWVRREIENFGGNKNRITLAGHSAGA 216
>7303171 [R] KOG1516 Carboxylesterase and related proteins
Length = 800
Score = 59.3 bits (142), Expect = 1e-08
Identities = 58/208 (27%), Positives = 89/208 (41%), Gaps = 23/208 (11%)
Query: 20 QGTLTGYTFKSPRTNNVTTHRFAQIPYAEPFTKENRFKRPVPLADDFDYTGDYKEFGLKC 79
QG L G T + F IPYA+ E RF P + F+ T C
Sbjct: 35 QGDLIGLKVFPDGTRGAV-YAFLGIPYAQAPINELRFA-PAKPSSSFNRTLQATTMQPLC 92
Query: 80 PQPSVPNPAFRYTKSPS-------DENINKLNIWVPSSD-KYKESDGWPVLVYIHGGWLQ 131
PQ + N + + S DE+ LNIW P S +Y + P++V + G
Sbjct: 93 PQ--LANTIYDESSDGSMPRSVSTDEDCLYLNIWTPESGMRYGKL---PIVVIVTGEEFA 147
Query: 132 YSSPYSEFFNTNEMFDDEEFTQKYILVTPGYRLNMFGFLSGKELLEEDEASSNFGFWDQR 191
Y P N + + + ++V+ YR N++G+LS E + N+G D +
Sbjct: 148 YDWP------RNRINGLDLAGEGIVVVSVQYRNNIYGWLSLGE--QHRNVPGNYGLSDVQ 199
Query: 192 LAIEWTYKYIKYFGGNPDKISVGGISAG 219
+A+ W + FGGNPD I++ G +G
Sbjct: 200 MALRWIRRNADAFGGNPDHITLLGHGSG 227
>CE15195 [R] KOG1516 Carboxylesterase and related proteins
Length = 687
Score = 58.9 bits (141), Expect = 2e-08
Identities = 60/219 (27%), Positives = 91/219 (41%), Gaps = 27/219 (12%)
Query: 21 GTLTGYTFKSPRT--NNVTTHRFAQIPYAEPFTKENRFKRPVPLADDFDYTGDYKEFGLK 78
GT+ G T + + N T F +PY EP RF++P P +D + KE+
Sbjct: 25 GTIEGRTLTASYSPLGNQTGIVFFGVPYVEPPVGNLRFRKPRP-PKPWDGVLEAKEYKAA 83
Query: 79 CPQPSVPNPAFRYTKSPSDENINKLNIWVPSSDKYKESDGWPVLVYIHGGW--LQYSSPY 136
C P E+ N++ ++ E V++ IHGG ++ +S Y
Sbjct: 84 CMSDQKKTYK-NGVGGPVSEDCLYANVF--TNQYCLEHKNCSVMLTIHGGRFVIESASAY 140
Query: 137 SEFFNTNEMFDDEEFTQKYILVTPGYRLNMFGFLSGKELLEEDEASSNFGFW-------- 188
N + ++VT YRL +FG +L D +NFG +
Sbjct: 141 DPEIIINNFVGQG---RNIVVVTFNYRLGLFGL----GMLNGDNQDTNFGLYGLKNLEIF 193
Query: 189 ----DQRLAIEWTYKYIKYFGGNPDKISVGGISAGAYST 223
D + WT K IK FGG+ D+I++ G SAGA T
Sbjct: 194 SLLPDILEVVRWTRKEIKNFGGDKDRITMQGHSAGAVFT 232
>CE06735 [R] KOG1516 Carboxylesterase and related proteins
Length = 552
Score = 58.9 bits (141), Expect = 2e-08
Identities = 70/280 (25%), Positives = 106/280 (37%), Gaps = 63/280 (22%)
Query: 39 HRFAQIPYAEPFTKENRFKRPVPLADDFDYTGDYKEFGLKCPQPSVPNPAFRYTKSPSDE 98
H F +IP+A+P RF++P A +D E+G C S TKSP
Sbjct: 37 HLFKKIPFAKPPVGNLRFQKP-EAAGKWDGIRSAIEYGPACMSNSSK------TKSPQK- 88
Query: 99 NINKLNIWVPSSDKYKESDGWPVLVYIHGGWLQYSSPYSEFFNTNEMFDDEEFTQKYILV 158
WV D +S + VYIHGG L Y S MF+D ++
Sbjct: 89 -------WV-DEDCLHKSRNCAIAVYIHGGGLTYDSAV--------MFNDTVLLDTFV-- 130
Query: 159 TPGYRLNMFGFLSGKELLEEDEASSNFGFWDQRLAIEWTYKYIKYFGGNPDKISVGGIS- 217
K + ++ A +N +D LA+E+ I FGGN KI++ G S
Sbjct: 131 --------------KRVHNQNVAPNNLALYDITLALEFVKSEIHSFGGNSQKITLFGHSY 176
Query: 218 AGAYSTFFQLAYELYHPEDNQIIKQALFFSNLVYVQ--------------------PKTI 257
G ++ + E+ D + +QA+ S Y + P +
Sbjct: 177 GGGLASMMTFSSEI--NRDLSLFQQAIVMSGGFYFEELKDHIEGTKRFVEYANCSVPLKL 234
Query: 258 EECQEQFDEIVEKLDIDPKASGQEKLAVLRELDAPFIEDF 297
E E+ + + + K SG E L + R L+ DF
Sbjct: 235 ERKMERSQQEMYMMKCLQKLSGMELLRIQRLLEDKGYPDF 274
>7298800 [R] KOG1516 Carboxylesterase and related proteins
Length = 568
Score = 58.9 bits (141), Expect = 2e-08
Identities = 56/210 (26%), Positives = 94/210 (44%), Gaps = 21/210 (10%)
Query: 39 HRFAQIPYAEPFTKENRFKRPVPLADDFDYTGDYKEFGLKCPQPSVPNPAFRYTKSPSDE 98
+ F IP+A+P + RF LAD ++ E + +P R K E
Sbjct: 64 YSFEGIPFAKPPLGKARFVAS-QLADPWN-----SELDARQERPIPLQMDRRSGKVVGSE 117
Query: 99 NINKLNIWVPSSDKYKESDG-WPVLVYIHGGWLQYSSPYSEFFNTNEMFDDEEFTQKYIL 157
+ LN++ + + ES+ PV+VYI+GG + + + + ++ +
Sbjct: 118 DCLYLNVY---TKHFNESEPPLPVMVYIYGGAFRTGGAVKSKYGPDYLM-----SRDVVY 169
Query: 158 VTPGYRLNMFGFLSGKELLEEDEASSNFGFWDQRLAIEWTYKYIKYFGGNPDKISVGGIS 217
V YRL GFLS + + N G DQ LA++W ++I+ F G+P I++ G S
Sbjct: 170 VLFNYRLCSLGFLSMPS--GKLDVPGNAGLHDQLLALQWVSQHIRNFNGDPQNITLFGES 227
Query: 218 AGAYSTFFQLAYELYHPEDNQIIKQALFFS 247
AGA S F + P+ + +A+ S
Sbjct: 228 AGAASVHFMMCL----PQAKGLFHKAIMMS 253
>Hs7706475 [R] KOG1516 Carboxylesterase and related proteins
Length = 288
Score = 58.2 bits (139), Expect = 3e-08
Identities = 56/208 (26%), Positives = 91/208 (42%), Gaps = 30/208 (14%)
Query: 41 FAQIPYAEPFTKENRFKRPVPLADDFDYTGD---YKEFGLKCPQPSVPNPAFRYTKSPSD 97
F IP+A+P RF P P A+ + + + Y + P+ + +T +
Sbjct: 51 FLGIPFAKPPLGPLRFTPPQP-AEPWSFVKNATLYPPMFTQDPRRGGQLISELFTNRKEN 109
Query: 98 ------ENINKLNIWVPSSDKYKESDGWPVLVYIHGGWLQYSSPYSEFFNTNEMFDDEEF 151
E+ LNI+ P+ + + PV+V+IHGG L + + +D
Sbjct: 110 IPLKLSEDCLYLNIYTPAD--LTKKNRLPVMVWIHGGGLMVGAAST--------YDGLAL 159
Query: 152 T--QKYILVTPGYRLNMFGFLSGKELLEEDEASSNFGFWDQRLAIEWTYKYIKYFGGNPD 209
+ ++VT YRL ++GF S ++ + N+G DQ A+ W I FGGNP
Sbjct: 160 AAHENVVVVTIQYRLGIWGFFS----TGDEHSPGNWGHLDQLAALHWVQDNIASFGGNPG 215
Query: 210 KISVGGISAGAYS----TFFQLAYELYH 233
+++ G SAG S LA L+H
Sbjct: 216 SVTIFGGSAGGESVSVLVLSPLAKNLFH 243
>CE23015 [R] KOG1516 Carboxylesterase and related proteins
Length = 672
Score = 57.4 bits (137), Expect = 5e-08
Identities = 57/218 (26%), Positives = 86/218 (39%), Gaps = 34/218 (15%)
Query: 41 FAQIPYAEPFTKENRFKRPVPLADDFDYTGDYKEFGLKCPQPSVPNPAFRYTKSPSDENI 100
F IPY + R + P PL D F KCPQ + P ++E+
Sbjct: 66 FTGIPYCQAPVGNLRLQPPQPLNQFNTTLHDATYFRPKCPQLNAGGP--------TNEDC 117
Query: 101 NKLNIWVPSSDKYKESDGWPVLVYIHGGWLQYSSPYSEFFNTNEMFDDEE-------FTQ 153
LN++ P + + VLV I G S F+ ++E +
Sbjct: 118 LYLNVYTPQAGNTNAN--LSVLVLIDG---------SNGFSNGGCDQNQEKGIISNLVQR 166
Query: 154 KYILVTPGYRLNMFGFLSGKELLEEDEASSNFGFWDQRLAIEWTYKYIKYFGGNPDKISV 213
+ ++VT YR+ GF + + SN G DQ A+ W I FGGNP++I+V
Sbjct: 167 QIVVVTMQYRIGALGFFT----TYTNSVQSNLGMLDQVQAMRWIKTEIVNFGGNPNQITV 222
Query: 214 GGISAGAYSTFFQLAYELYHPEDNQIIKQALFFSNLVY 251
G GA + ++ P + QA+ S VY
Sbjct: 223 AGQDDGACA----VSAHCLSPMSQNLFNQAIVQSGSVY 256
>CE18546 [R] KOG1516 Carboxylesterase and related proteins
Length = 798
Score = 56.6 bits (135), Expect = 9e-08
Identities = 60/260 (23%), Positives = 98/260 (37%), Gaps = 38/260 (14%)
Query: 40 RFAQIPYAEPFTKENRFKRPVPLADDFDYTGDYKEFGLKCPQPSVPN----PAFRYTKSP 95
++ IPY T + RF + A D ++ C Q +P AF++T +
Sbjct: 47 QYLGIPYGVAPTGQYRFNMAISAAKWTHMPKDARKVSPVCIQTDMPELSETKAFKHTSAQ 106
Query: 96 --------------SDENINKLNIWVPSSDKYKESDGWPVLVYIHG---GWLQYSSPYSE 138
E+ +NI+VP + + PV+V +HG GW
Sbjct: 107 RFDFNHRLLPHLKKQSEDCLYMNIYVPERLEISRDNYLPVMVIVHGEEYGW--------- 157
Query: 139 FFNTNEMFDDEEFTQ--KYILVTPGYRLNMFGFLSGKELLEEDEASSNFGFWDQRLAIEW 196
T F+ I+VT YRL +FGFL E S N G D A+
Sbjct: 158 --GTGNAFNGTTLAAYGHIIVVTLNYRLGVFGFLGR---CESSSCSGNSGISDLVSALTM 212
Query: 197 TYKYIKYFGGNPDKISVGGISAGAYSTFFQLAYELYHPEDNQIIKQALFFSNLVYVQPKT 256
+ FGG+ +++ G +GA +A L P ++ ++A+
Sbjct: 213 LNVILPSFGGDSKSVTLAGWGSGASLVSLLMASPLTQP-GRRLFRRAILLDGSALSPWAI 271
Query: 257 IEECQEQFDEIVEKLDIDPK 276
+ Q+ F ++ E+L PK
Sbjct: 272 SQNPQQYFMQLAEELACAPK 291
>CE26673 [R] KOG1516 Carboxylesterase and related proteins
Length = 583
Score = 56.2 bits (134), Expect = 1e-07
Identities = 58/201 (28%), Positives = 92/201 (44%), Gaps = 21/201 (10%)
Query: 21 GTLTGYTFKSPRTNNVTTHRFAQIPYAEPFTKENRFKRPVPLADDFDYTGDYKEFGLKCP 80
G L G S N+ T F +P+A+P RF P L D +D D + C
Sbjct: 26 GKLRGMAEWSDDANHKFT--FKSVPFAKPPIGNLRFAPPQKL-DHWDGILDASVYSAACM 82
Query: 81 QPSVPNPAFRYTKSPSDENINKLNIWVPSSDKYKESDGWPVLVYIHGGWLQYSSPYSEFF 140
S T+S +E+ +NI+ +S+K +S V+VY HGG Y++ + F
Sbjct: 83 SNSTLT-----TQSYVNEDCLYINIF--TSEKCLKSK-CSVIVYFHGG--AYNTESATMF 132
Query: 141 NTNEMFDDEEFTQKYILVTPGYRLNMFG--FLSGKELLEEDEASSNFGFWDQRLAIEWTY 198
+ + D + I V P RL +FG + L E N +D LA+++ +
Sbjct: 133 SDRFILD-RYVHEDVIFVIPAVRLGVFGQLYFGPNAYLTE-----NLFMFDAILALDFVH 186
Query: 199 KYIKYFGGNPDKISVGGISAG 219
I FGG+P+K+++ G S+G
Sbjct: 187 NEISNFGGDPEKVTIMGHSSG 207
>7298806 [R] KOG1516 Carboxylesterase and related proteins
Length = 572
Score = 55.8 bits (133), Expect = 2e-07
Identities = 52/209 (24%), Positives = 89/209 (41%), Gaps = 30/209 (14%)
Query: 41 FAQIPYAEPFTKENRFKRPVPLADDFDYTGDYKEFGLKCPQPSVPNPAFRYTKSPSDENI 100
F +IP+A+P E R+K P P + + + + P+P + F T E+
Sbjct: 42 FERIPFAKPPVGELRYKAPQPP----EVWTEVRSCTSQGPKPLQKHFVFEMTDG--SEDC 95
Query: 101 NKLNIWVPSSDKYKESDGWPVLVYIHGGWLQYSSPYSEFFNTNEMFDDEEFTQKYILVTP 160
LN++ + K PV+V+I+GG Q+ E ++ + + ++ ++++
Sbjct: 96 LYLNVYTKNLYPTKPM---PVMVWIYGGGFQFGEASRECYSPDYLLRED-----VVVISI 147
Query: 161 GYRLNMFGF--------------LSGKELLEEDEAS--SNFGFWDQRLAIEWTYKYIKYF 204
YRL G L G L++ E N G DQ LA+ W F
Sbjct: 148 NYRLGPLGTNDDTWKKKHIFNISLPGFLCLDDPELDVPGNAGLKDQVLALRWVKANCSRF 207
Query: 205 GGNPDKISVGGISAGAYSTFFQLAYELYH 233
GG+ I++ G SAG+ S + + E H
Sbjct: 208 GGDSANITIFGDSAGSASVHYMMITEQTH 236
>CE07376 [R] KOG1516 Carboxylesterase and related proteins
Length = 431
Score = 55.1 bits (131), Expect = 3e-07
Identities = 32/101 (31%), Positives = 52/101 (50%), Gaps = 11/101 (10%)
Query: 122 LVYIHGGWLQYSSP--YSEFFNTNEMFDDEEFTQKYILVTPGYRLNMFGFLSGKELLEED 179
+VYIHGG + S+ Y ++ + + ++VT YR+ + GF + + +
Sbjct: 1 MVYIHGGGYECSASRDYCDYSVAGTLP-----LKDVVVVTLNYRVGILGFFTTGDTV--- 52
Query: 180 EASSNFGFWDQRLAIEWTYKYIKYFGGNPDKISVGGISAGA 220
NF WD L + W K+I+ FGG+P I++ G SAGA
Sbjct: 53 -CPGNFALWDLTLGLNWIQKHIESFGGDPGNITIFGQSAGA 92
>7298796 [R] KOG1516 Carboxylesterase and related proteins
Length = 541
Score = 55.1 bits (131), Expect = 3e-07
Identities = 57/191 (29%), Positives = 78/191 (39%), Gaps = 19/191 (9%)
Query: 39 HRFAQIPYAEPFTKENRFKRPVPLADDFDYTGDYKEFGLKCPQPSVPNPAFRYTKS-PSD 97
+ F IPYA P RFK P L K KC Q S TK
Sbjct: 33 YAFDGIPYAVPPLGTLRFKEPHDLKPWHGIRDCSKPLS-KCLQVST------LTKEVEGS 85
Query: 98 ENINKLNIWVPSSDKYKESDGWPVLVYIHGGWLQYSSPYSEFFNTNEMFDDEEFTQKYIL 157
E+ LNI V K D PV+VYIHGG + + D + +
Sbjct: 86 EDCLYLNISV----KTLNGDPMPVMVYIHGGAFKGGDSSRRAWGP-----DYFMKENVVY 136
Query: 158 VTPGYRLNMFGFLSGKELLEEDEASSNFGFWDQRLAIEWTYKYIKYFGGNPDKISVGGIS 217
++ G+RL GFLS + + E N G D LA+ W F G+P++I++ G S
Sbjct: 137 ISIGHRLGPLGFLSLND--PDLEVPGNAGLKDVILALRWIRANAANFNGDPERITIFGHS 194
Query: 218 AGAYSTFFQLA 228
+G+ + LA
Sbjct: 195 SGSMTVQLLLA 205
>Hs7662400 [R] KOG1516 Carboxylesterase and related proteins
Length = 648
Score = 54.3 bits (129), Expect = 5e-07
Identities = 34/101 (33%), Positives = 48/101 (46%), Gaps = 14/101 (13%)
Query: 122 LVYIHGGWLQYSSPYSEFFNTNEMFDDEEFTQ--KYILVTPGYRLNMFGFLSGKELLEED 179
+VYIHGG S T M D I++T YRL + GFLS +
Sbjct: 1 MVYIHGG--------SYMEGTGNMIDGSILASYGNVIVITINYRLGILGFLS----TGDQ 48
Query: 180 EASSNFGFWDQRLAIEWTYKYIKYFGGNPDKISVGGISAGA 220
A N+G DQ A+ W + + FGG+P ++++ G AGA
Sbjct: 49 AAKGNYGLLDQIQALRWIEENVGAFGGDPKRVTIFGSGAGA 89
>7297441 [R] KOG1516 Carboxylesterase and related proteins
Length = 674
Score = 53.5 bits (127), Expect = 8e-07
Identities = 58/215 (26%), Positives = 87/215 (39%), Gaps = 34/215 (15%)
Query: 13 FPISIPGQGTLTGYTFKSPRTNNVTTHRFAQIPYAEPFTKENRFKRPVPLADDFDYTGDY 72
F ++P G L G T + T +F IPY K RF+ P + G
Sbjct: 76 FTTTVPDLGRLRGRTLTTDWTGQKIM-QFLDIPYG----KAERFRPAEPAPS---WKGVL 127
Query: 73 KEFGLKCPQPSVPNPAFRYTKSPSD----ENINKLNIWVPSSDKYKESDGWPVLVYIHGG 128
PS+ + + K D E+ +L++ + K E PV+VYIHG
Sbjct: 128 PAHRPHAGCPSIQD-LIVFAKLEEDGFDVEDCLRLSV----NTKAMEGKSLPVMVYIHG- 181
Query: 129 WLQYSSPYSEFFNTNEMFDDEE---FTQKYILVTPGYRLNMFGFLSGKELLEEDEASSNF 185
+FF + + +LV+ YRL FGFLS DE N
Sbjct: 182 ---------DFFYDGDSVEAAPGYLLEHDVVLVSVRYRLGPFGFLSTLT----DEMPGNA 228
Query: 186 GFWDQRLAIEWTYKYIKYFGGNPDKISVGGISAGA 220
D LA++W ++I FGG+P ++++ G GA
Sbjct: 229 AVTDIILALKWVQQHIASFGGDPQRVTLFGQVGGA 263
>7297439 [R] KOG1516 Carboxylesterase and related proteins
Length = 1026
Score = 53.5 bits (127), Expect = 8e-07
Identities = 34/101 (33%), Positives = 50/101 (48%), Gaps = 11/101 (10%)
Query: 120 PVLVYIHGGWLQYSSPYSEFFNTNEMFDDEEFTQKYILVTPGYRLNMFGFLSGKELLEED 179
PVLV++HG L + E D + +LV+ YRL FGFLS D
Sbjct: 160 PVLVFVHGEMLFDGG-------SEEAQPDYVLEKDVLLVSINYRLAPFGFLSALT----D 208
Query: 180 EASSNFGFWDQRLAIEWTYKYIKYFGGNPDKISVGGISAGA 220
E N D +LA+EW + + +FGGN ++++ G + GA
Sbjct: 209 ELPGNVALSDLQLALEWLQRNVVHFGGNAGQVTLVGQAGGA 249
>CE08329 [R] KOG1516 Carboxylesterase and related proteins
Length = 1187
Score = 53.1 bits (126), Expect = 1e-06
Identities = 61/233 (26%), Positives = 102/233 (43%), Gaps = 24/233 (10%)
Query: 21 GTLTGYTFKSPRTNNVTTHRFAQIPYAEPFTKENRFKRPVPLADDFDYTGDYKEFGLKCP 80
G + G T S N+ + F +P+A+P + RF P D + D ++ C
Sbjct: 29 GRVRGITEWSDDNNH--KYMFKSVPFAKPPIGKLRFAPP-QYPDSWSGVLDASKYSPACL 85
Query: 81 QPSVPNPAFRYTKSPSDENINK--LNIWVPSSDKYKESDGWPVLVYIHGGWLQYSSPYSE 138
S T S E++++ L I + +S+K S V+VY HGG Y+ +
Sbjct: 86 SNSS-------TTSTPQEHVSEDCLYINIFTSEKCLRSK-CAVIVYFHGG--AYNGDSAT 135
Query: 139 FFNTNEMFDDEEFTQKYILVTPGYRLNMFG--FLSGKELLEEDEASSNFGFWDQRLAIEW 196
F N + + + IL PG RL +FG + LL E N +D A+++
Sbjct: 136 MFPDNFILE-RYVAEDVILAIPGVRLGVFGQLYFGPSALLTE-----NLFMFDAVQALDF 189
Query: 197 TYKYIKYFGGNPDKISVGGISAGAYSTFFQLAYELYHPEDNQIIKQALFFSNL 249
+ I FGG+P ++++ G S+G + L + Y + LFFS++
Sbjct: 190 VHNEIPNFGGDPKQVTIMGHSSGG-TLVEALGFSKYQILSCLAAENILFFSSV 241
>CE14347 [R] KOG1516 Carboxylesterase and related proteins
Length = 539
Score = 52.4 bits (124), Expect = 2e-06
Identities = 53/201 (26%), Positives = 85/201 (41%), Gaps = 38/201 (18%)
Query: 20 QGTLTGYTFKSPRTNNVTTHRFAQIPYAEPFTKENRFKRPVPLADDFDYTGDYKEFGLKC 79
QG L G+ ++ + + F IPYAEP + RF++P P
Sbjct: 22 QGFLEGFCVQTAKGDLCDV--FHGIPYAEPPIGKLRFQKPQP------------------ 61
Query: 80 PQPSVPNPAFRYTKSPSDENINKLNIWVPSSDKYKESDGWPVLVYIHGGWLQYSSPYSEF 139
P + K P+ +I+K W + +S+ +Y++ ++ E
Sbjct: 62 --PKAWEGIRKCNKYPN-RSIHKEMPWDKALPSANQSED---CLYLN----VFAPKIRED 111
Query: 140 FNTNEMFDDEEFTQKYILVTPGYRLNMFGFLSGKELLEEDEASSNFGFWDQRLAIEWTYK 199
N ++ E I+VT YRL GFLS +D N+G +D A+ W +
Sbjct: 112 KNICKLLVSREI----IVVTFHYRLGFLGFLS----TGDDVCPGNYGLFDMLEAMRWVHA 163
Query: 200 YIKYFGGNPDKISVGGISAGA 220
I FGG+P+ I++ G SAGA
Sbjct: 164 NISSFGGDPENITLSGQSAGA 184
>Hs18594215 [R] KOG1516 Carboxylesterase and related proteins
Length = 327
Score = 50.1 bits (118), Expect = 9e-06
Identities = 25/67 (37%), Positives = 38/67 (56%), Gaps = 4/67 (5%)
Query: 156 ILVTPGYRLNMFGFLSGKELLEEDEASSNFGFWDQRLAIEWTYKYIKYFGGNPDKISVGG 215
++V YRL +FGF + + A N+ F DQ A+ W K I++FGG+P +++ G
Sbjct: 43 LVVIVQYRLGIFGFFT----TWDQHAPGNWAFKDQVAALSWVQKNIEFFGGDPSSVTIFG 98
Query: 216 ISAGAYS 222
S GA S
Sbjct: 99 ESVGAIS 105
>7298791 [R] KOG1516 Carboxylesterase and related proteins
Length = 298
Score = 50.1 bits (118), Expect = 9e-06
Identities = 31/112 (27%), Positives = 54/112 (47%), Gaps = 11/112 (9%)
Query: 119 WPVLVYIHGGWLQYSSPYSEFFNTNEMFDDEEFTQ--KYILVTPGYRLNMFGFLSGKELL 176
+PVLV++HG ++ N+ +D + ++VT YRL + GFL+
Sbjct: 56 YPVLVFVHGESYEW--------NSGNPYDGSVLASYGQILVVTINYRLGVLGFLNANTD- 106
Query: 177 EEDEASSNFGFWDQRLAIEWTYKYIKYFGGNPDKISVGGISAGAYSTFFQLA 228
+ +N+G D A+ W + I FGG+P+ I++ G GA F ++
Sbjct: 107 RYSKLPANYGLMDIIAALHWLKENIAAFGGDPNSITLAGHGTGAACVHFLIS 158
>7297184 [R] KOG1516 Carboxylesterase and related proteins
Length = 1016
Score = 50.1 bits (118), Expect = 9e-06
Identities = 41/132 (31%), Positives = 60/132 (45%), Gaps = 27/132 (20%)
Query: 103 LNIWVPSSDKYK-----ESDGWP-----VLVYIHGGWLQYSSPYSEFFNTNEMFDDEEFT 152
LNI+VP + + ++ G P +V+IHG S +N+ +D E
Sbjct: 64 LNIYVPYETRRQRRNTDDTTGEPKTKLSTVVFIHGE--------SYDWNSGNPYDGSELA 115
Query: 153 Q--KYILVTPGYRLNMFGFLS--GKELLEEDEASSNFGFWDQRLAIEWTYKYIKYFGGNP 208
I+VT +RL +FGFL GKE A NFG D + W + + FGG+P
Sbjct: 116 AHGNVIVVTINFRLGIFGFLKTGGKE-----SAQGNFGLMDLVAGLHWLKENLPAFGGDP 170
Query: 209 DKISVGGISAGA 220
I++ G GA
Sbjct: 171 QSITLLGYGTGA 182
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.318 0.139 0.431
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 38,373,002
Number of Sequences: 60738
Number of extensions: 1940983
Number of successful extensions: 4330
Number of sequences better than 1.0e-05: 90
Number of HSP's better than 0.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 80
Number of HSP's that attempted gapping in prelim test: 4113
Number of HSP's gapped (non-prelim): 111
length of query: 545
length of database: 30,389,216
effective HSP length: 111
effective length of query: 434
effective length of database: 23,647,298
effective search space: 10262927332
effective search space used: 10262927332
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)