ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIV2859 good G KOG2533 Carbohydrate transport and metabolism Permease of the major facilitator superfamily
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIV2859 970243 971805 521
(521 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YJR152w [G] KOG2533 Permease of the major facilitator superfamily 437 e-122
SPCC417.10 [G] KOG2533 Permease of the major facilitator superfa... 401 e-111
SPBC1773.15 [G] KOG2533 Permease of the major facilitator superf... 399 e-111
SPCC757.13 [G] KOG2533 Permease of the major facilitator superfa... 269 9e-72
YLR004c [G] KOG2533 Permease of the major facilitator superfamily 238 2e-62
SPBPB10D8.01 [G] KOG2533 Permease of the major facilitator super... 174 4e-43
YLL055w [G] KOG2533 Permease of the major facilitator superfamily 172 8e-43
SPCPB1C11.03 [G] KOG2533 Permease of the major facilitator super... 170 5e-42
SPBC1683.12 [G] KOG2533 Permease of the major facilitator superf... 157 5e-38
YGR260w [G] KOG2533 Permease of the major facilitator superfamily 152 2e-36
SPAC11D3.18c [G] KOG2533 Permease of the major facilitator super... 144 2e-34
SPAC1039.04 [G] KOG2533 Permease of the major facilitator superf... 140 4e-33
SPAC1002.16c [G] KOG2533 Permease of the major facilitator super... 118 2e-26
YIL166c [G] KOG2533 Permease of the major facilitator superfamily 100 9e-21
SPBC2G2.01c [G] KOG2533 Permease of the major facilitator superf... 80 1e-14
SPAC1B3.16c [G] KOG2533 Permease of the major facilitator superf... 79 1e-14
YCR028c [G] KOG2533 Permease of the major facilitator superfamily 62 3e-09
YAL067c [G] KOG2533 Permease of the major facilitator superfamily 59 2e-08
>YJR152w [G] KOG2533 Permease of the major facilitator superfamily
Length = 543
Score = 437 bits (1124), Expect = e-122
Identities = 229/517 (44%), Positives = 336/517 (64%), Gaps = 15/517 (2%)
Query: 18 QDATTEDVPLQTILSPSGKVLVLGEAADEAMEFAKHHEHIELSAEEDRKVKRKIDMIVMP 77
+D T E V L T+LSP+GK++ + + DEAM+ A+ + IE++ EEDRK++ KID + P
Sbjct: 29 EDVTAEPV-LSTVLSPNGKIVYISDKVDEAMKLAEEAKEIEVTPEEDRKLRWKIDYCMFP 87
Query: 78 LFSFLYMIQFMDKTCISFAAVMGIQTDYKMVDTMYSWTTSCFYLGYLFAS--PFAAVALQ 135
L LY +QFMDK S AAVMG++TD KM YSW TS FY GYLF + P + +
Sbjct: 88 LMCILYAVQFMDKISTSSAAVMGLRTDLKMHGDQYSWVTSAFYFGYLFMNLGPVQFIFQR 147
Query: 136 KLPSMRTSAICIVIWGVIQCLHVTAK-SYATFTLLRTLLGVLEAFVSPIFVIMMNQYYKK 194
+ A+ IVIWG++ LH Y +F +LR LLG E+ V+P F I+ QY+K
Sbjct: 148 TSHMSKMLAVFIVIWGMLLALHAAPTVKYPSFIVLRVLLGCAESVVTPCFTIITAQYWKT 207
Query: 195 SEHFGYIGVLYGCNGLGTVILACISYGLYHNLGSYTMEAYKVLFIIVGCLTIFNGLLILF 254
E F + + +G NGLG++++ I+YG+Y + SY ++ ++ LF+I G +TIF G+LI
Sbjct: 208 EEQFTRVSIWFGMNGLGSILINAIAYGVYIHQDSYAIKGWRTLFVITGVITIFIGILIFL 267
Query: 255 IMPNTPADARFLNDREKLAVLERIRGNNQGFGSKTFKWHQMKECFMDMRTWLYFLIGISV 314
+P+ P+ ARFL+ REKL V++RIR N QGFG+ K +Q+ E D+RTWLYFL +S
Sbjct: 268 WIPDDPSKARFLSKREKLMVVQRIRSNQQGFGNHEIKKYQIIEALKDVRTWLYFLFTVSS 327
Query: 315 AIPNGGISSFGSIILKG-FGYSTEKSLLMKAPIGACELVGLVILPLISYFISKRMI---- 369
IPNGGISSF SI+L FGYS++++LLM P GA ELVG + +++ + + + I
Sbjct: 328 NIPNGGISSFMSILLNSDFGYSSKETLLMGLPTGAVELVGCPLFGILAVYAANKKIPFWK 387
Query: 370 ----IAVFYLLVCVMSTCLLAFSKN-KNVALAGYYITGIAPVGIITITSCVASNTAGHTK 424
A+F ++ ++++C+L F+ N K LAG Y+ I+PV I + S +++N++G++K
Sbjct: 388 YKLSWAIFAAVLALIASCMLGFATNSKKARLAGAYLWYISPVSFICVLSNISANSSGYSK 447
Query: 425 KLTANAISLIGYSAGNIVGPQTFRSSDAPNYPKAKAAVVGCYCASIALMGLMSFLNVREN 484
K T ++I+L+ Y+A N+ GPQTF + AP Y AK A+V CY I L+ ++ +N+REN
Sbjct: 448 KWTVSSINLVAYAAANLAGPQTFIAKQAPKYHGAKVAMVVCYAVMIVLLSILLIVNLREN 507
Query: 485 RRRDKMQEELGDKYVVVENQEFADLTDFENPAFRYSL 521
+RRDK+ E G EN EF+DLTDFENP FRY+L
Sbjct: 508 KRRDKIAAERGFP-EETENLEFSDLTDFENPNFRYTL 543
>SPCC417.10 [G] KOG2533 Permease of the major facilitator superfamily
Length = 508
Score = 401 bits (1030), Expect = e-111
Identities = 211/515 (40%), Positives = 318/515 (60%), Gaps = 14/515 (2%)
Query: 8 DQTIEKCESVQDATTEDVPLQTILSPSGKVLVLGEAADEAMEFAKHHEHIELSAEEDRKV 67
D+ ++ ESVQ+ DV + LSP G D A +A ++ E+ E +R++
Sbjct: 7 DEKLKDPESVQNKEILDVDVGD-LSPKG--------VDAAFNYALDVDYDEIDPETERRL 57
Query: 68 KRKIDMIVMPLFSFLYMIQFMDKTCISFAAVMGIQTDYKMVDTMYSWTTSCFYLGYLFAS 127
RKID + P+ +Y IQF+DKT S+A +MG++ D KM MYSW+ + FYLGYL
Sbjct: 58 VRKIDCTIFPVMCLVYCIQFLDKTSNSYAVIMGLKEDLKMEGQMYSWSGTAFYLGYLVFE 117
Query: 128 PFAAVALQKLPSMRTSAICIVIWGVIQCLHVTAKSYATFTLLRTLLGVLEAFVSPIFVIM 187
A++ LQ+ P +T + +VIWG + C+ A +Y F LR LLG++E+ SP F+++
Sbjct: 118 FPASLLLQRFPLSKTLCVFLVIWGFLLCMTSVA-NYPGFIALRVLLGMMESAASPGFILL 176
Query: 188 MNQYYKKSEHFGYIGVLYGCNGLGTVILACISYGLYHNLGSYTMEAYKVLFIIVGCLTIF 247
Q+YK+SE V NGLG ++ +C++YGL S M +K++FII G L IF
Sbjct: 177 TAQWYKRSEQQLRTSVWVAFNGLGQILGSCMAYGLAKRT-SLPMRGWKLIFIICGVLAIF 235
Query: 248 NGLLILFIMPNTPADARFLNDREKLAVLERIRGNNQGFGSKTFKWHQMKECFMDMRTWLY 307
G +IL ++P+ P A FL + ++ V++R+R N QG G+ FK +Q KE +D+RTW+
Sbjct: 236 LGFVILAVVPDNPFKAWFLTEEDRKLVVKRLRANKQGVGNNHFKLYQFKETMLDIRTWIM 295
Query: 308 FLIGISVAIPNGGISSFGSIILKG-FGYSTEKSLLMKAPIGACELVGLVILPLISYFISK 366
F+ + + IPNGGI +F S+++KG GY T ++LLM P GACE GL+ +S FI K
Sbjct: 296 FVSSVLLNIPNGGIGTFSSLLIKGTMGYDTLQTLLMGLPAGACEFGGLIAFGFLSLFIHK 355
Query: 367 RMIIAVFYLLVCVMSTCLLAFSKNKNVALAGYYITGIAPVGIITITSCVASNTAGHTKKL 426
RM++A + ++ +CLL+F+ LAGYY+ ++P +I + + ++SN +G+TKK+
Sbjct: 356 RMVLATITTCIALIGSCLLSFAGPPRAQLAGYYLLMVSPGAMIVMFAIISSNASGYTKKV 415
Query: 427 TANAISLIGYSAGNIVGPQTFRSSDAPNYPKAKAAVVGCYCASIALMGLMSFLNVRENRR 486
T I LIGY GN++GPQTF+++DAP Y AK +VGCY A++ + ++N REN+R
Sbjct: 416 TVGVIYLIGYCVGNLIGPQTFKAADAPEYMPAKNTMVGCYAATLVTFPALYYVNWRENKR 475
Query: 487 RDKMQEELGDKYVVVENQEFADLTDFENPAFRYSL 521
RD++ E K N EF DLTDFEN FRY+L
Sbjct: 476 RDQLAAE--GKIEHRPNAEFEDLTDFENLDFRYTL 508
>SPBC1773.15 [G] KOG2533 Permease of the major facilitator superfamily
Length = 497
Score = 399 bits (1026), Expect = e-111
Identities = 209/479 (43%), Positives = 309/479 (63%), Gaps = 7/479 (1%)
Query: 45 DEAMEFAKHHEHIELSAEEDRKVKRKIDMIVMPLFSFLYMIQFMDKTCISFAAVMGIQTD 104
D A+ FA+ H I+ S +RK+K K D+ VMPL + Q+MDK+ +++++MGI+TD
Sbjct: 24 DVAVIFAEKHPIIDKSL--NRKLKLKTDLWVMPLLCLISAFQYMDKSTSNYSSIMGIRTD 81
Query: 105 YKMVDTMYSWTTSCFYLGYLFASPFAAVALQKLPSMRTSAICIVIWGVIQCLHVTAKSYA 164
MV Y+W + FYLG++ S + LQK P + ++ IV WG++ L SYA
Sbjct: 82 LNMVGNQYNWVGTSFYLGFMVFSLPLSTLLQKFPLSKVTSAFIVAWGILMTLTCLVHSYA 141
Query: 165 TFTLLRTLLGVLEAFVSPIFVIMMNQYYKKSEHFGYIGVLYGCNGLGTVILACISYGLYH 224
++ RTLLG+LE+ ++P FV+ + Q+Y+K E F + L NGLG +I +SYGLY
Sbjct: 142 SYIATRTLLGILESVITPAFVLFIAQWYRKEEQFFRMAFLVAWNGLGGLIGGSMSYGLYK 201
Query: 225 NL--GSYTMEAYKVLFIIVGCLTIFNGLLILFIMPNTPADARFLNDREKLAVLERIRGNN 282
+ TM +++LFII G +TI NG+ I +P+ P+ A FL+++EK VL+R+ ++
Sbjct: 202 RELENNLTMSPWRILFIITGLITIINGVFIFIHIPDEPSKAWFLSEKEKDLVLKRLDTDH 261
Query: 283 QGFGSKTFKWHQMKECFMDMRTWLYFLIGISVAIPNGGISSFGSIILKGFGYSTEKSLLM 342
G GSK FK +Q+ E D+R +LYF + I+VAIPNGG+S+F SI+LK GY K+LLM
Sbjct: 262 AGLGSKKFKKYQILEACRDVRMYLYFFLQIAVAIPNGGLSNFSSIMLKNLGYVKGKALLM 321
Query: 343 KAPIGACELVGLVILPLISYFISKRMIIAVFYLLVCVMSTCLLAFSKNKNVALAGYYITG 402
P + L + LI F ++RM IA+ L + + S L+AF+K + LAGY++ G
Sbjct: 322 NMPTSSISFAALTLFGLIPEFTNRRMDIALVGLAINLTSGSLIAFAKPTHAQLAGYWLFG 381
Query: 403 IAPVGIITITSCVASNTAGHTKKLTANAISLIGYSAGNIVGPQTFRSSDAPNYPKAKAAV 462
I+P+ I I SC++SN+AGHTKK+ +A+S+IGY GN+VGPQTFRS+ AP Y AK +
Sbjct: 382 ISPIPYICILSCISSNSAGHTKKVFMSAVSMIGYCVGNMVGPQTFRSTQAPKYQGAKVSF 441
Query: 463 VGCYCASIALMGLMSFLNVRENRRRDKMQEELGDKYVVVENQEFADLTDFENPAFRYSL 521
V CYC +I ++ + +NVRENRRRD+ E L ++ + ++ DLTDFENP FRYS+
Sbjct: 442 VVCYCVAIFIIIAIYAVNVRENRRRDEKNEYLSNE---LSEEDKKDLTDFENPEFRYSI 497
>SPCC757.13 [G] KOG2533 Permease of the major facilitator superfamily
Length = 522
Score = 269 bits (687), Expect = 9e-72
Identities = 157/464 (33%), Positives = 255/464 (54%), Gaps = 9/464 (1%)
Query: 60 SAEEDRKVKRKIDMIVMPLFSFLYMIQFMDKTCISFAAVMGIQTDYKMVDTMYSWTTSCF 119
+A+E R+V KID+++MP+ YMIQ++DKT +S+AA+ G++TD + YS T+ F
Sbjct: 62 TAKEARRVLWKIDLVMMPVMCITYMIQYLDKTALSYAALYGMKTDTHIDGHTYSSMTTLF 121
Query: 120 YLGYLFASPFAAVALQKLPSMRTSAICIVIWGVIQCLHVTAKSYATFTLLRTLLGVLEAF 179
Y GYL A AA+ +QK + +W + CL ++ + LR L G+ EA
Sbjct: 122 YAGYLVAQYPAAILMQKCRLSYFIFCNVFLWSAMVCLMAACRNGPSLLGLRFLAGIFEAS 181
Query: 180 VSPIFVIMMNQYYKKSEHFGYIGVLYGCNGLGTVILACISYGLYHNLGSYTMEAYKVLFI 239
++P F+ + +Y++ E Y NG+ +I + +SYGL H G + +++ +FI
Sbjct: 182 ITPAFINITAMWYRREEQPMRTLCWYAFNGIAQIIGSILSYGLGHIHGK--VASWRYVFI 239
Query: 240 IVGCLTIFNGLLILFIMPNTPADARFLNDREKLAVLERIRGNNQGFGSKTFKWHQMKECF 299
++G +++ G++ +FI P+ P+ ARFL+ REK LER+R N G +K FKW E F
Sbjct: 240 VIGLMSLGWGVVFVFI-PSNPSKARFLSSREKRIALERVRDNRTGLENKQFKWKHAYEAF 298
Query: 300 MDMRTWLYFLIGISVAIPNGGISSFGSIILKGFGYSTEKSLLMKAPIGACELVGLVIL-P 358
+D + + L V + GI F ++I+KG GY+ S ++ P+GA E+ + I
Sbjct: 299 LDPQVIMITLF-TGVCMITNGIGVFSTLIIKGLGYNELHSAVLNMPLGAIEVAAMFISGV 357
Query: 359 LISYFISKRMIIAVFYLLVCVMSTCLLAF---SKNKNVALAGYYITGIAPVGIITITSCV 415
L F + R++I VF + ++ CL+ + N L G + T P + S +
Sbjct: 358 LCKVFKNGRLLIGVF-MNCLTLAGCLMIWKIPDSNPYGRLVGVWFTMWVPASSALLLSLI 416
Query: 416 ASNTAGHTKKLTANAISLIGYSAGNIVGPQTFRSSDAPNYPKAKAAVVGCYCASIALMGL 475
+SN AG+TKK +A + YS GNIV PQ F+S P Y + A++ C IA+ +
Sbjct: 417 SSNVAGYTKKTVTSATVFVFYSVGNIVSPQLFKSGQTPEYIEGIQAMIVSLCIIIAIAFV 476
Query: 476 MSFLNVRENRRRDKMQEELGDKYVVVENQEFADLTDFENPAFRY 519
++ + EN+RRD++ E ++N+EF DLTD + P FRY
Sbjct: 477 LTGYYIYENKRRDRLLAEDPSLGESIKNEEFMDLTDRQQPKFRY 520
>YLR004c [G] KOG2533 Permease of the major facilitator superfamily
Length = 523
Score = 238 bits (606), Expect = 2e-62
Identities = 150/480 (31%), Positives = 242/480 (50%), Gaps = 19/480 (3%)
Query: 43 AADEAMEFAKHHEHIELSAEEDRKVKRKIDMIVMPLFSFLYMIQFMDKTCISFAAVMGIQ 102
A +EA + H ELS KV RK+D+ ++P Y++ F+DK +++AA MGI+
Sbjct: 58 AGEEANFYGSH----ELSP----KVLRKVDLFILPFLCCTYLLMFLDKALLNYAASMGIK 109
Query: 103 TDYKMVDTMYSWTTSCFYLGYLFASPFAAVALQKLPSMRTSAICIVIWGVIQCLHVTAKS 162
K +S + F Y+F P +QK P + I +WG++ H K+
Sbjct: 110 DHLK--GNEFSNLGTIFSAAYIFMEPVVTYLIQKFPISKILGTFITVWGIVLACHAACKT 167
Query: 163 YATFTLLRTLLGVLEAFVSPIFVIMMNQYYKKSEHFGYIGVLYGCNGLGTVILACISYGL 222
YA+ ++RTLLG+ E+ + + + YY KSE IG G G ++ IS+G
Sbjct: 168 YASLMVVRTLLGLFESSSAVGCIAISGMYYTKSEQSARIGFWATQAGTGYIVGGLISFGF 227
Query: 223 YHNLGSYTMEAYKVLFIIVGCLTIFNGLLILFIMPNTPADARFLNDREKLAVLERIRGNN 282
H G+ +++++F++VG +T+ G+L +P+ +A FLN EK+ V+E IR N
Sbjct: 228 LHYHGT-AFTSWQIMFLVVGLVTVAFGVLTFLYLPDNVTNAWFLNKEEKIQVVEHIRANQ 286
Query: 283 QGFGSKTFKWHQMKECFM-DMRTWLYFLIGISVAIPNGGISSFGSIILKGFGYSTEKSLL 341
G +K FK Q+KE F+ D TW L+ I G I +F I FG+ ++ L
Sbjct: 287 TGLETKKFKKQQVKELFLHDKFTWPMLLLTACSQISTGAIGTFSVTITGTFGFDKYETAL 346
Query: 342 MKAPIGA-CELVGLVILPLISYFISKRMIIAVFYLLVCVMSTCLLAFSKNKNVA-LAGYY 399
++ PIGA ++ L+ ++S + +I Y+ + L++ + + L Y
Sbjct: 347 LQLPIGAITAMIILITTQMLSRWGHITLITTSMYIPAIIGCIVLISLPLSHKIGNLFSLY 406
Query: 400 ITGIAPVGIITITSCVASNTAGHTKKLTANAISLIGYSAGNIVGPQTFRSSDAPNYPKAK 459
+ I I + NT+G+TK++ NAI++I Y+ I+ PQ FR+ AP Y AK
Sbjct: 407 LLYSGSCVITNIYIWNSCNTSGYTKRVFRNAITMIVYNVSCIIAPQMFRAYSAPRYIPAK 466
Query: 460 AAVVGCYCASIALMGLMSFLNVRENRRRDKMQEELGDKYVVVENQEFADLTDFENPAFRY 519
A++ C + L + ++ +EN +RDK QE K +F DLTD EN FRY
Sbjct: 467 IALLVTQCVCVPLQLYIGYICKKENEKRDKEQEGQERK-----KYQFLDLTDIENRNFRY 521
>SPBPB10D8.01 [G] KOG2533 Permease of the major facilitator superfamily
Length = 552
Score = 174 bits (440), Expect = 4e-43
Identities = 130/503 (25%), Positives = 236/503 (46%), Gaps = 34/503 (6%)
Query: 45 DEAMEFAKHHEHIE-LSAEEDRKVKRKIDMIVMPLFSFLYMIQFMDKTCISFAAVMGIQT 103
DE F + + +E L+ ++D++++ K+ V+ + L M+ ++DK +S+++++G+
Sbjct: 58 DETFSFMQEAKDLEPLTPKQDKRLRWKLYFTVLVMLMILDMMLYIDKATLSYSSILGLFE 117
Query: 104 DYKMVDTMYSWTTSCFYLGYLFASPFAAVALQKLPSMRTSAICIVIWGVIQCLHVTAKSY 163
D + Y+ + FY+G++ + LQ+ P + A +W +I LH A ++
Sbjct: 118 DTHINSNQYNDINTLFYVGFVIGQIPGHMLLQRFPVSKFVAASTALWTIIIFLHCAAYNF 177
Query: 164 ATFTLLRTLLGVLEAFVSPIFVIMMNQYYKKSEH-----FGYIGVLYGCNGLGTVILACI 218
+ LR LG++E+ + P + ++ SE F YI YGCN + I
Sbjct: 178 SGLMALRFFLGLVESSLLPTMEATIGMFFPHSEQALLQPFFYIS-CYGCN----IPAGFI 232
Query: 219 SYGLYHNLGSYTMEAYKVLFIIVGCLTIFNGLLILFIMPNTPADARFLNDREKLAVLERI 278
+YG+ + T+ +K+ IIVG +T F + + F P+ + ARFL +E+L ++R+
Sbjct: 233 AYGVQY--AKNTISPWKLFMIIVGGITFFLTIGLFFYYPDNTSTARFLTKKERLYTVDRV 290
Query: 279 -RGNNQGFGSKTFKWHQMKECFMDMRTWLYFLIGISVAIPNGGISSFGSIILKGFGYSTE 337
R N+ G SKTFK +Q+ E D TWL+ + N ++ +++ S
Sbjct: 291 RRSNHSGIESKTFKKYQVIEALKDPVTWLFTFHVFCNQLSN-NLAYQQNLLFTSLNVSDL 349
Query: 338 KSLLMKAPIGACELVGLVILPLISYFISKRMII--AVFYLLVCVMSTCLLAFSKNKNVA- 394
S L+ V +I + I + A++Y+ +A S + +
Sbjct: 350 NSTLVGVASAGYNCVSAIIATYMMSVIKNQSAFHGAIWYIPSIAGGIACVAMSWDHKIGE 409
Query: 395 LAGYYITGIAPVGIITITSCVASNTAGHTKKLTANAISLIGYSAGNIVGPQTFRSSDAPN 454
LA I + I ++ AG+TKKLT + +IGY+ NI+GPQ ++S DAP
Sbjct: 410 LAAIIIASNFGIPFIISLGWTTASCAGYTKKLTRGVMFMIGYAIANIIGPQMWQSRDAPR 469
Query: 455 -YPKAKAAVVGCYCASIALMGLMSFLNVRENRRRDKMQEELGDKYVVV------------ 501
YP +V + S ++ ++ ++ VR N++R + E+ ++Y
Sbjct: 470 YYPAWIVQIVIAWSVSPFVLLIIRWILVRRNKKRLALLEQNKEQYEKTWIETIDSSGNHV 529
Query: 502 ---ENQEFADLTDFENPAFRYSL 521
DLTD EN +F Y L
Sbjct: 530 SGFYENSMLDLTDQENLSFIYPL 552
>YLL055w [G] KOG2533 Permease of the major facilitator superfamily
Length = 531
Score = 172 bits (437), Expect = 8e-43
Identities = 128/521 (24%), Positives = 242/521 (45%), Gaps = 32/521 (6%)
Query: 31 LSPSGKVLVLGEAADEAMEFAKHHEHI--ELSAEEDRKVKRKIDMIVMPLFSFLYMIQFM 88
+S S ++LV AD + F + ++ E++ E+++K+KRK+ + + S + ++ +M
Sbjct: 13 ISSSDEILVPSRLADVTLAFMEENDAAVPEITPEQEKKLKRKLFLTIFTFVSAINLLLYM 72
Query: 89 DKTCISFAAVMGIQTDYKMVDTMYSWTTSCFYLGYLFASPFAAVALQKLPSMRTSAICIV 148
DK +S+ +++G D + Y+ + FY+G+ QKLP + +
Sbjct: 73 DKATLSYDSILGFFEDTGLTQNTYNTVNTLFYVGFAIGQFPGQYLAQKLPLGKFLGGLLA 132
Query: 149 IWGVIQCLHVTAKSYATFTLLRTLLGVLEAFVSPIFVIMMNQYYKKSEHFGYIGVLYGCN 208
W ++ L TA +++ LR LG+ E+ V PI + M ++ SE +
Sbjct: 133 TWTILIFLSCTAYNFSGVVALRFFLGLTESVVIPILITTMGMFFDASERAAAQPFFFAAC 192
Query: 209 GLGTVILACISYGLYHNLGSYTMEAYKVLFIIVGCLTIFNGLLILFIMPNTPADARFLND 268
+ I+YG+ H + + ++ +K+ II+G LT ++++ PN PAD +F +
Sbjct: 193 MGSPIPTGFIAYGVLH-ITNPSISLWKIFTIIIGGLTFIMTVVVILWFPNNPADVKFFSI 251
Query: 269 REKLAVLERIRGN-NQGFGSKTFKWHQMKECFMDMRTWLYFLIGISVAIPNGGISSFGSI 327
+E++ ++ R++ + K FK Q +E D TWL+ L + + N + ++
Sbjct: 252 QERVWIIRRVQASTGSSIEQKVFKKSQFREAMKDYITWLFGLFFLLQQLAN-NLPYQQNL 310
Query: 328 ILKGFG--YSTEKSLLMKAPIGACELVGLVILPLISYFISKRMIIAVFYLLVCVMSTCLL 385
+ +G G + +L+ A G + + +++ + + + A+F+ L ++ +
Sbjct: 311 LFEGMGGVDALGSTLVSVAGAGFAVVCAFIATLMLAKWKNISALTAIFWTLPALVGSIAA 370
Query: 386 AFS--KNKNVALAGYYITG-IAPVGIITITSCVASNTAGHTKKLTANAISLIGYSAGNIV 442
A NK LA + G I + I S +S+ +G+TKKLT +++SL NI+
Sbjct: 371 AALPWDNKIGILANICMAGQIFGIPFIIALSWASSSASGYTKKLTRSSVSLFAMGIANII 430
Query: 443 GPQTFRSSDAPNY-PKAKAAVVGCYCASIALMGLMSFLNVRENRRRDKMQEELGDKY--- 498
PQ +R D+P + P +V + + A++ L+ F+ R N +R K +E Y
Sbjct: 431 SPQIWREKDSPRFLPAWIVQIVLSFSLAPAILLLIHFILKRRNNQRLKNYDENLQNYLDR 490
Query: 499 ----------------VVVENQEFA--DLTDFENPAFRYSL 521
VV A DLTD EN F Y L
Sbjct: 491 IQLIESENPSSIEEGKVVTHENNLAVFDLTDLENETFIYPL 531
>SPCPB1C11.03 [G] KOG2533 Permease of the major facilitator superfamily
Length = 570
Score = 170 bits (430), Expect = 5e-42
Identities = 138/552 (25%), Positives = 241/552 (43%), Gaps = 41/552 (7%)
Query: 4 TDMKDQTIEKCESVQDATT-----EDVPLQTILSPSGKVLVLGEAADEAMEFAKHHEHIE 58
TD +EK E+ D T D + + GK + DE F + + ++
Sbjct: 26 TDSSSLDLEKKENAVDTTIAKPFDSDEDIADVEKAGGKK-INNSLIDETFAFMQDAKKLD 84
Query: 59 -LSAEEDRKVKRKIDMIVMPLFSFLYMIQFMDKTCISFAAVMGIQTDYKMVDTMYSWTTS 117
L+ +++ K+K K+ + ++ + FL M+ F+ K +S++ ++G+ D + Y+ +
Sbjct: 85 PLTPKQESKLKWKLYIYLLLMLGFLDMMLFIGKATLSYSTILGLFDDVHITSNQYNNLNT 144
Query: 118 CFYLGYLFASPFAAVALQKLPSMRTSAICIVIWGVIQCLHVTAKSYATFTLLRTLLGVLE 177
FY+GY+ +Q P + + W VI LH A +Y LR LG E
Sbjct: 145 LFYVGYIVGQFPGHYIMQTFPLGKFVGLVTFSWSVIVFLHCCAYNYGGLIALRFFLGFTE 204
Query: 178 AFVSPIFVIMMNQYYKKSEHFGYIGVLY-GCNGLGTVILACISYGLYHNLGSYTMEAYKV 236
+ + P M ++ E V + C G + I+YGL + ++ +K+
Sbjct: 205 SCLLPAMEATMGMFFTHQEQAFLQPVFWISCLSCG-IPAGFIAYGL--EFVTKSIAPWKL 261
Query: 237 LFIIVGCLTIFNGLLILFIMPNTPADARFLNDREKLAVLERIRGNNQ-GFGSKTFKWHQM 295
II G +T F + + F P+ P+ ARFL D EKL ++R+R + + G +K FK HQ
Sbjct: 262 FMIITGGITFFLSIFLFFYYPDNPSKARFLTDEEKLYTIDRVRKSTRGGIENKIFKKHQF 321
Query: 296 KECFMDMRTWLYFLIGISVAIPNGGISSFGSIILKGFGYSTEKSLLMKAPIGACELVGLV 355
E D TWL+ ++ + N ++ ++I S S L+ + V +
Sbjct: 322 IEALKDPITWLFTFAAFTLMLSN-NLAYQQNLIFTSLNVSDLNSTLVGVALAGYNTVSAI 380
Query: 356 ILPLISYFISKRMII-AVFYLLVCVMSTCLLAFS----KNKNVALAGYYITGIAPVGIIT 410
I Y I + A+F++L + T +AF N+ LA I + I
Sbjct: 381 IATFAMYLIPNQSAYHAMFWMLPSI--TGGIAFVALPWSNRIGELATMIIASDFGITYII 438
Query: 411 ITSCVASNTAGHTKKLTANAISLIGYSAGNIVGPQTFRSSDAPN-YPKAKAAVVGCYCAS 469
+ + G+TKKLT + ++GY+ NI+ PQ ++S DAP YP +V + +
Sbjct: 439 ALGWTTATSTGYTKKLTRGLMFMVGYAIANIISPQLWQSRDAPRYYPAWIVQIVVAWFVT 498
Query: 470 IALMGLMSFLNVRENRRRDKMQ--------------------EELGDKYVVVENQEFADL 509
+ + + R N++R +++ +E G+ V+ + DL
Sbjct: 499 PIIYLVARVILARRNKQRKELKDKKIAEGSLETIEKTYVDTVDEFGNPVKVLIDNSMLDL 558
Query: 510 TDFENPAFRYSL 521
TD EN F Y L
Sbjct: 559 TDMENLNFVYPL 570
>SPBC1683.12 [G] KOG2533 Permease of the major facilitator superfamily
Length = 482
Score = 157 bits (396), Expect = 5e-38
Identities = 125/462 (27%), Positives = 209/462 (45%), Gaps = 11/462 (2%)
Query: 55 EHIELSAEEDRKVKRKIDMIVMPLFSFLYMIQFMDKTCISFAAVMGIQTDYKMVDTMYSW 114
+ I + +E+ K+ RK+D +MP+FS LY + F+D+ I AAV+G++ D K+ YS
Sbjct: 24 DDITIEKKEEAKLVRKLDWYLMPMFSVLYFLSFLDRANIGNAAVVGLKEDLKLQAYQYSA 83
Query: 115 TTSCFYLGYLFASPFAAVALQKLPSMRTSAICIVIWGVIQCLHVTAKSYATFTLLRTLLG 174
S FY Y+ A + + ++K + I+ W ++ + Y + L R LLG
Sbjct: 84 AVSVFYATYITAETPSVLLVKKFGPHYYLSAMIIGWSLVTIFTCFVRHYWSLVLTRLLLG 143
Query: 175 VLEAFVSPIFVIMMNQYYKKSEHFGYIGVLYGCNGLGTVILACISYGLYHNLGSYTMEAY 234
+ E P + ++ YK+ E + LY C+ I+ GL S + +
Sbjct: 144 ICEGGFFPCLSLYISMTYKREEQGKRLAYLYVCSCFSGAFGGLIATGLTKIPKSSGLPNW 203
Query: 235 KVLFIIVGCLTIFNGLLILFIMPNTPADARFLNDREKLAVLERIRGNNQGFGSKTFKWHQ 294
L+II G ++ + L ILF +P+ P+ ARFLN REK + R + GS F W Q
Sbjct: 204 GWLYIIEGLISAISALWILFCLPDDPSTARFLNPREKELMKIRAEQRQKYMGSPNFDWTQ 263
Query: 295 MKECFMDMRTWLYFLIGISVAIPNGGISSFGSIILK-GFGYSTEKSLLMKAPIGACELVG 353
++ F D + ++ +I + GIS+F ILK GYS+ + M P+ A +
Sbjct: 264 FRKAFKDPKMYMSCVIQFCQDLVLYGISTFLPSILKLELGYSSLAAQYMSVPVYALGGIS 323
Query: 354 LVILPLISYFISKR--MIIAVFYLLVCVMSTCLLAFSKNKNVALAGYYITGIAPVGIITI 411
+ ++ L+S + R II + + + L + N + P + I
Sbjct: 324 VYVICLLSDRTNIRGWFIIGMNFFGLAGFIILLATTNSAANYVATYLIALPLYPTVALNI 383
Query: 412 TSCVASNTAGHTKKLTA-NAISLIGYSAGNIVGPQTFRSSDAPNYPKAKAAVVGCYCASI 470
T + +N A H ++ TA IG AG I G Q +RSS Y +GC
Sbjct: 384 T-WINNNMAPHYRRATALGCNQTIGNLAGVIAG-QVYRSSP---YKLGHGFALGCTVVGT 438
Query: 471 ALMGLMSFLNVRENRRRDKMQEELGDKYVVVENQEFADLTDF 512
M F R+N+ + ++ G++ + ++ D DF
Sbjct: 439 LTATAMRFYLQRQNKIKQEILN--GERVDEKKERDGCDALDF 478
>YGR260w [G] KOG2533 Permease of the major facilitator superfamily
Length = 534
Score = 152 bits (383), Expect = 2e-36
Identities = 118/492 (23%), Positives = 220/492 (43%), Gaps = 28/492 (5%)
Query: 45 DEAMEFAKHHEHIELSAEED----------RKVKRKIDMIVMPLFSFLYMIQFMDKTCIS 94
D+ E A E + + ++D ++V RK+D+ ++PL LY + +DK+ I
Sbjct: 52 DKKSELATEREIMATTTDDDGIPSPSHPMEKRVLRKMDIYLIPLMGMLYFLSNLDKSNIG 111
Query: 95 FAAVMGIQTDYKMVDTMYSWTTSCFYLGYLFASPFAAVALQKLPSMRTSAICIVIWGVIQ 154
A V G+ D +V T Y+ + F+ Y+ P L+ + +IC+ +G I
Sbjct: 112 NAEVAGLSKDIHLVGTQYNTCVTVFFATYVLFDPIGTNLLKIMGPPLMMSICLTCFGAIS 171
Query: 155 CLHVTAKSYATFTLLRTLLGVLEAFVSPIFVIMMNQYYKKSEHFGYIGVLYGCNGLGTVI 214
K+YA ++R LLG E + P + ++ Y++ ++ ++ L +
Sbjct: 172 LGTAWVKNYAQLIVVRLLLGAFEGMIYPAINMYLSVCYRREQYALRFAFVFSAACLSSSF 231
Query: 215 LACISYGLYHNLGSYTMEAYKVLFIIVGCLTIFNGLLILFIMPNTPADARFLNDREKLAV 274
I+YG GS ++ ++ ++I+ GC+++ F + D+ F N EK +
Sbjct: 232 GGLIAYGCSKISGS--LKDWQYIYIVEGCISLGFVPFYAFGLSKNLEDSWFFNKEEKEYI 289
Query: 275 LERIRGNNQGFGSKTFKWHQMKECFMDMRTWLYFLIGISVAIPNGGISSFGSIILKGFGY 334
ER + N + F+W Q+ + D++TW + + + G++ F II+ G+
Sbjct: 290 SERYKTMNTFDPDEKFEWFQVWQAVKDVKTWASAVALFGIDLTTFGLTVFLPIIITSMGF 349
Query: 335 STEKSLLMKAPIGACELVGLVILPLISYFISKRMIIAVFYLLVCVMSTCLLAFSKNKNVA 394
+ ++ LM PI + I + S I R + F L C+ ++ +A V
Sbjct: 350 TNVRAQLMTVPIYFLTAIVFFICAVWSDRIKLR---SPFILGACLTTSIGIAIVLGSQVH 406
Query: 395 LAGYYITGIAPVGIITITSC----VASNTAGHTKKLTANAISLIGYSAGNIVGPQTFRSS 450
Y+ I +GI +C ++ NT + K+ TA I+L S +V Q F +
Sbjct: 407 GVRYFGVYILCMGIYVNAACNCLWLSGNTGNYFKRATALGINLFFGSGSGLVSGQIFVAK 466
Query: 451 DAPNYPKAKAAVVGCYCASIALMGLMSFLNVRENRRRDKMQE---ELGDKYVVVENQEFA 507
D P Y K + + SI + + FL REN ++ + + ELG+ + ++ +
Sbjct: 467 DKPRYIKGLSISLAFQVFSIFMTVVQIFLYKRENDKKKAIIDRCNELGEP--IPYDERLS 524
Query: 508 DLTDFENPAFRY 519
D +NP F+Y
Sbjct: 525 D----KNPEFKY 532
>SPAC11D3.18c [G] KOG2533 Permease of the major facilitator superfamily
Length = 498
Score = 144 bits (364), Expect = 2e-34
Identities = 103/441 (23%), Positives = 196/441 (44%), Gaps = 16/441 (3%)
Query: 57 IELSAEEDRKVKRKIDMIVMPLFSFLYMIQFMDKTCISFAAVMGIQTDYKMVDTMYSWTT 116
+++ + ++K+ K+D+++ P+ FLY++ F+D++ I AAV G+ + +
Sbjct: 43 LKIDPKVEKKLLLKMDLVISPIIGFLYLMAFLDRSNIGNAAVAGMTEALSLYGERLNVAV 102
Query: 117 SCFYLGYLFASPFAAVALQKLPSMRTSAICIVIWGVIQCLHVTAKSYATFTLLRTLLGVL 176
S FY+ Y+ + V ++++ + R A W + SY R +LG+L
Sbjct: 103 SIFYVLYILVETPSVVLVKRIKASRMLAFISFAWSMTVLFSGFMSSYGGLIATRLILGLL 162
Query: 177 EAFVSPIFVIMMNQYYKKSEHFGYIGVLYGCNGLGTVILACISYGLYHNLGSYTMEAYKV 236
E + P + + +Y + E + L+ GL +Y L + + E ++
Sbjct: 163 EGCLFPALNLYLTTHYTRKEQCQRLSYLFASAGLAGAFGGLFAYAL-EQVHAGNKEGWQW 221
Query: 237 LFIIVGCLTIFNGLLILFIMPNTPADARFLNDREKLAVLERIRGNNQGFGSKTFKWHQMK 296
++I+ G ++ L LF +P+ +A FL E+ + R N + G + F+W +++
Sbjct: 222 IYIVEGLVSFIGVPLCLFALPDKMENAWFLTREEREVAIIRRDINARYHGEQHFEWSEVR 281
Query: 297 ECFMDMRTWLYFLIGISVAIPNGGISSFGSIILKGFGYSTEKSLLMKAPIGACELVGLVI 356
+ F D + ++ + G SSF +I+KG G+ ++ M P+ ++ +
Sbjct: 282 KAFKDPKVYVSATSQFCADMVLYGFSSFLPVIIKGLGFVGLQTNYMTIPVYIAGVISFLF 341
Query: 357 LPLIS--------YFISKRMIIAVFYLLVCVMSTCLLAFSKNKNVALAGYYITGIAPVGI 408
+ +S Y IS ++AV Y++ +LA N A Y I +G
Sbjct: 342 VAWLSDRTQLRAVYLISASTVVAVGYII-------MLASDSNAAKYTATYIIAIGCYIGP 394
Query: 409 ITITSCVASNTAGHTKKLTANAISLIGYSAGNIVGPQTFRSSDAPNYPKAKAAVVGCYCA 468
+ +N AGH K+ TA I ++ IV Q +RS +AP Y A +GC
Sbjct: 395 GLNLGWLNNNVAGHYKRATAIGIQQTLANSSGIVAGQIYRSKNAPKYILGNAFTLGCVIV 454
Query: 469 SIALMGLMSFLNVRENRRRDK 489
+M F N++RD+
Sbjct: 455 GGLAYVVMFFSLRYVNKKRDE 475
>SPAC1039.04 [G] KOG2533 Permease of the major facilitator superfamily
Length = 507
Score = 140 bits (354), Expect = 4e-33
Identities = 111/479 (23%), Positives = 214/479 (44%), Gaps = 32/479 (6%)
Query: 59 LSAEEDRKVKRKIDMIVMPLFSFLYMIQFMDKTCISFAAVMGIQTDYKMVDTMYSWTTSC 118
L + +R++ RK D ++PL + LY+ +DK+ +S A G+ D V Y+ S
Sbjct: 45 LDHKAERRLCRKFDFRILPLLALLYLFNALDKSNVSNAKTNGMDKDLGFVGDQYNIMISI 104
Query: 119 FYLGY-LFASPFAAVALQKLPSMRTSAICIVIWGVIQCLHVTAKSYATFTLLRTLLGVLE 177
FY+ + L A PF+ + ++ + R ++ +G + K++ +R LG+ E
Sbjct: 105 FYIPFVLCAFPFSYL-YKRFGAARILPFFMLSFGAMSLCQAAVKNFGGMMAVRWFLGMAE 163
Query: 178 AFVSPIFVIMMNQYYKKSEHFGYIGVLYGCNGLGTVILACISYGLYHNLGSYTMEAYKVL 237
+ V P V + +Y+++E + + Y + + ++YG++H G ++ ++ L
Sbjct: 164 SAVLPGVVYYLTTFYRRTELARRLAIFYAAANVSSAFGGLLAYGVFHIKGG-KLQGWQYL 222
Query: 238 FIIVGCLTIFNGLLILFIMPNTPADARFLNDREKLAVLERIRGNNQGFGSKTFKWHQMKE 297
F+I G +T ++I ++P + A FL D EK RI ++ S+ + Q
Sbjct: 223 FLIEGGVTFLCAIVIFLVLPVSVETANFLTDEEKTLAKMRIENDSSSAISEKLSFKQSLT 282
Query: 298 CFMDMRTWLYFLIGISVAIPNGGISSFGSIILKGFGYSTEKSLLMKAPIGACELVGLVIL 357
F L+ L +++ +P I+++ I+ G+S+ + LM + L++
Sbjct: 283 VFKHPIAILWLLEEMALGVPLNSINNWLPQIVAAMGFSSVNTNLMTVAPAISGAIWLLVF 342
Query: 358 PLISYFISKRMIIAVFYLLVCVMSTCLLAFSKNKNVAL---------AGYYITGIAPVGI 408
IS F+ R I+ L+ +ST ++ F ++ + A + +T A
Sbjct: 343 AFISDFLKNRGIV-----LIAAISTTMIGFIVYGSIDIMNHIGVSYFACFLMTAGAAASS 397
Query: 409 ITITSCVASNTAGHTKKLTANAISLIGYSAGNIVGPQTFRSSDAPNYPKAKAAVVGCYCA 468
+ ++ +NT +++ ++ + + +V FR DAP Y A G
Sbjct: 398 VLTSTWYNNNTPNESRRAVFTSVGVPLANVMGLVSANIFRPQDAPKYVPALGITAGFGGL 457
Query: 469 SIALMGLMSFLNVRENRRRDKMQEELGDKYVVVENQEFADLTDFE------NPAFRYSL 521
I L+ +S +NRRRD Q G K + FAD++ + NP FR+ L
Sbjct: 458 GILLVASISVYMFFDNRRRDNAQ---GVK------KTFADVSTKDLGEGPANPNFRWFL 507
>SPAC1002.16c [G] KOG2533 Permease of the major facilitator superfamily
Length = 499
Score = 118 bits (296), Expect = 2e-26
Identities = 92/401 (22%), Positives = 171/401 (41%), Gaps = 12/401 (2%)
Query: 55 EHIELSAEEDRKVKRKIDMIVMPLFSFLYMIQFMDKTCISFAAVMGIQTDYKMVDTMYSW 114
E+ L+ E + ++D+++ P LY++ F+D++ I A V G+ D K+ ++
Sbjct: 39 ENTHLTKSERDSLLFRLDLVLAPTIMILYLVAFLDRSNIGNAKVAGLPEDLKLKGDQFNI 98
Query: 115 TTSCFYLGYLFASPFAAVALQKLPSMRTSAICIVIWGVIQCLHVTAKSYATFTLLRTLLG 174
S FY+ ++ + ++K+ R A ++ + + ++ R +LG
Sbjct: 99 IASVFYVTFILFEMPTTLLMKKVQPKRMLAFIVISYSLTTIFTGFCHNFGGLLAARLVLG 158
Query: 175 VLEAFVSPIFVIMMNQYYKKSEHFGYIGVLYGCNGLGTVILACISYGLYHNLGSYTMEAY 234
EA + P + + Y + E I L+ + L +Y + H G +
Sbjct: 159 FCEAGLFPCLALYLTMIYSRVELAPRIAYLFASSALSGAFGGLFAYAVLHMDGVGGFAGW 218
Query: 235 KVLFIIVGCLTIFNGLLILFIMPNTPADARFLNDREKLAVLERIRGNNQGFGSKTFKWHQ 294
+ LFII G + G+ + FI+PN A FL+ + + +R + F W
Sbjct: 219 RWLFIIEGLIGFVCGVAVYFIIPNDITKAWFLSKTHQEMMRKRQLERAADLEAAHFDWKG 278
Query: 295 MKECFMDMRTWLYFLIGISVAIPNGGISSFGSIILKGFGYSTEKSLLMKAPI---GACEL 351
+K F D + +LY L G S+F I+ G GY++ M P+ GA
Sbjct: 279 VKSAFTDFKVYLYALSEFGQDTCLYGFSTFLPAIISGMGYTSLSVQYMTIPVYILGAATY 338
Query: 352 VGLVILPLISYFISKRMIIAVFYLLVCVMSTCLLAFSKNKNVALAGYYITGIAPVGIIT- 410
+ L F + +I+ + + V LLA NK+V Y+ + VG+ T
Sbjct: 339 IAASFLS--DRFHHRGIILIIGNIFPIVGYILLLACQNNKSVL---YFACYLCSVGVYTG 393
Query: 411 ---ITSCVASNTAGHTKKLTANAISLIGYSAGNIVGPQTFR 448
+ +++N A H K+ TA ++ L ++ I+ Q +R
Sbjct: 394 AGLNVTWLSANIAPHYKRATAISLQLAIANSSGILAGQIYR 434
>YIL166c [G] KOG2533 Permease of the major facilitator superfamily
Length = 542
Score = 99.8 bits (247), Expect = 9e-21
Identities = 103/455 (22%), Positives = 195/455 (42%), Gaps = 38/455 (8%)
Query: 62 EEDRKVKRKIDMIVMPLFSFLYMIQFMD--KTCISFAAVMGIQTDYKMVDTMYSWTTSCF 119
+E++K+ RK+D+ + L+ F+ M F+D + I+ A D KM Y+ + +
Sbjct: 68 DEEKKLVRKMDLKIF-LWVFI-MFAFLDLIRKNIARAVSDNFIVDLKMNTNDYNLGQTVY 125
Query: 120 YLGYLFASPFAAVALQKLPSMRTSAICIVIWGVIQCLHVTAKSYATFTLLRTLLGVLEAF 179
+ +L + + ++ R + IV+W VI K+ F R LLG+++
Sbjct: 126 LVIFLASELPGNLLSKRFGPERVIPVQIVLWSVICITQAGLKNRGQFIATRCLLGMVQGG 185
Query: 180 VSPIFVIMMNQYYKKSEHFGYIGVLYGCNGLGTVILACISYGLYHNLGSYTMEAYKVLFI 239
P ++ ++ YY +E + + L ++ + ++ G+ G + + ++ LFI
Sbjct: 186 FIPDNILYLSYYYTGAELTFRLSFFWCAIPLFQILGSLLASGIIEMRGIHNLAGWQYLFI 245
Query: 240 IVGCLTIFNGLLILFIMPNTPAD----------ARFLNDREKLAVLERIR-----GNNQG 284
I G L++ G+ ++M P + F EK+ V +R G+
Sbjct: 246 IEGFLSLSVGVASFYLMRRGPTQTGESAFHKGKSLFTEYEEKIMVNRILRDDPSKGDMSN 305
Query: 285 FGSKTFKWHQMKECFMDMRTWLYFLIGISVAIPNGGISSFGSIILKGFGYSTEKSLLMKA 344
TFK ++ + W F+ GI+ I + S+ S+ILK YST S ++
Sbjct: 306 RQPVTFK--EILYTLTEFDLWPLFIQGITAFISLQTVGSYLSLILKSLNYSTFLSNILAI 363
Query: 345 PIGACELVGLVILPLISYFISKRMI---IAVFYLLVCVMSTCLLAFSKN---KNVALAGY 398
P A L+ L + L+S + ++ + IA ++L ++S L N K + L G
Sbjct: 364 PGQALLLINLPLAALLSRKLKEKSLCVGIANVWVLPFIVSLVALPTDTNPWIKYILLTGI 423
Query: 399 ----YITGIAPVGIITITSCVASNTAGHTKKLTANAISLIGYSAGNIVGPQTFRSSDAPN 454
Y I + I++ V S T G A+ + G I+ +R+ D P
Sbjct: 424 LGLPYTHSILAGWVSEISNSVRSRTVG-------TALYNMSAQVGAIIASNMYRNDDKPY 476
Query: 455 YPKAKAAVVGCYCASIALMGLMSFLNVRENRRRDK 489
Y + ++G C +I + F + N+ +D+
Sbjct: 477 YTRGNKILLGFTCFNICMAVATKFYYISRNKYKDR 511
>SPBC2G2.01c [G] KOG2533 Permease of the major facilitator superfamily
Length = 514
Score = 79.7 bits (195), Expect = 1e-14
Identities = 55/218 (25%), Positives = 101/218 (46%), Gaps = 3/218 (1%)
Query: 64 DRKVKRKIDMIVMPLFSFLYMIQFMDKTCISFAAVMGIQTDYKMVDTMYSWTTSCFYLGY 123
++K+ KID ++ Y I ++D++ I+ A + G+Q D KM F GY
Sbjct: 21 EQKLLIKIDWFILSYCCVSYFINYLDRSSINNAYLSGMQEDLKMHGNELQDINVVFTCGY 80
Query: 124 LFASPFAAVALQKLPSMRTSAICIVIWGVIQCLHVTAKSYATFTLLRTLLGVLEAFVSPI 183
+ + ALQ++P+ ++ ++WG++ S +LR + V EA
Sbjct: 81 IIGQLPGSYALQRVPARLWFSVMNILWGLMTIFSFAVHSVRALMILRFFMAVAEASTFAG 140
Query: 184 FVIMMNQYYKKSEHFGYIGVLYGCNGLGTVILACISYGLYHNL-GSYTMEAYKVLFIIVG 242
++ +YK+SE G+ +GT+ + ++ +L G + ++ LFII G
Sbjct: 141 THYILGAWYKESELCKRAGIFSASGLVGTMFAGYLQTAVHSSLNGKGGLSGWRWLFIIDG 200
Query: 243 CLTIFNGLLILFIMPNTP--ADARFLNDREKLAVLERI 278
LTI L LF+ P+ P A + ++EK +R+
Sbjct: 201 ILTIPLSLYGLFLFPDVPETTKAPYFTEQEKELSFKRL 238
>SPAC1B3.16c [G] KOG2533 Permease of the major facilitator superfamily
Length = 568
Score = 79.3 bits (194), Expect = 1e-14
Identities = 99/475 (20%), Positives = 191/475 (39%), Gaps = 61/475 (12%)
Query: 45 DEAMEFAKHHEHIELSAEEDRKVKRKIDMIVMPLFSFLYMIQFMDKTCISFAAVMGIQTD 104
D A K E +K++ K+D+ ++P LY + + +S + M
Sbjct: 55 DGAETTVKEQEFTSSELRRLQKLRLKMDLRIIPCLWILYFLSCCLRFTVSLSFTMNTAQG 114
Query: 105 YKMVDTMYSWTT-------SCFYLGYL-FASPFAAVALQKLPSMRTSAICIVIWGVIQCL 156
+ ++ T+ ++ + FY+GY+ F P + P + S I + I V C
Sbjct: 115 HSLIQTLSGYSAHYLALGLALFYVGYIIFEVPSNLMMAFIEPRIWVSRIQLTIGVVGACH 174
Query: 157 HVTAKSYA---TFTLLRTLLGVLEAFVSPIFVIMMNQYYKKSEHFG-YIGVLYGCNGLGT 212
V + ++ LR LGV E+ + P M+++Y + +H G IG Y +
Sbjct: 175 AVLGTKHGNAQSYVALRFFLGVAESGLWPGLAYYMSRWY-RGKHLGKRIGWYYTAAQIAA 233
Query: 213 VILACISYGLYHNLGSYTMEAYKVLFIIVGCLTIFNGLLILFIMPN-------------- 258
++ +S G G+ + Y+ +F+I G + I L I + +P
Sbjct: 234 AAVSLVSAGFQKMDGARGLYGYQWMFLIWGVVAIAQALSIPWWLPAVASKEHRKSLSSFI 293
Query: 259 ---------TPADARFLNDREKLAVLERIRGNNQGFGSKTFKWHQMKECFMDMRTWLYFL 309
+P FL +K I N G K ++W + + +D+R W + L
Sbjct: 294 PLPKWMKTLSPQRIGFLTPADKSLHSRYIAEMNVG---KRWQWSDLLKSCLDLRVWPFIL 350
Query: 310 IGISVAIPNGGISSFGSIILKGF--GYSTEKSLLMKAPIGACELVGLV-ILPLISYFISK 366
+ + GI ++ ++I++ +S L+ API + +G+V ++PL F K
Sbjct: 351 MYFGIVGVGNGIFNYCTLIIEEINPSFSGIDISLLNAPIWLADALGIVTVMPLYDRFHKK 410
Query: 367 RMIIAVFYLLV----CVMSTCLLAFSKNKNVALAGYYITGIAPVGIITITSCVASNTAGH 422
L++ V + A+S+ + + G+ G+ P I + C AS +
Sbjct: 411 FSFFTGSCLIIIAGLAVANYAPRAWSRYGGLLMIGF---GLGPTVPICMAWCSASMAKTY 467
Query: 423 TKKLTANAISLIG--YSAGNIV----------GPQTFRSSDAPNYPKAKAAVVGC 465
A++++L+ + G++V G TFR S+ +++ C
Sbjct: 468 GDVGVASSLALVTGLGNLGSVVTTYALYSGWPGDPTFRKSNDVCIALIGVSIIAC 522
>YCR028c [G] KOG2533 Permease of the major facilitator superfamily
Length = 512
Score = 61.6 bits (148), Expect = 3e-09
Identities = 77/376 (20%), Positives = 147/376 (38%), Gaps = 27/376 (7%)
Query: 54 HEHIELSAEEDRKVKR-----KIDMIVMPLFSFLYMIQFMDKTCISFAAVMGIQTDYKMV 108
HE S R +K+ KID+ V+ Y I ++D+ + A + G++ D KMV
Sbjct: 11 HEVERESVSSKRAIKKRLLLFKIDLFVLSFVCLQYWINYVDRVGFTNAYISGMKEDLKMV 70
Query: 109 DTMYSWTTSCFYLGYLFASPFAAVALQKLPSMRTSAICIVIWGVIQCLHVTAKSYATFTL 168
+ + + F +GY+ + L +P + C WG++ S+
Sbjct: 71 GNDLTVSNTVFMIGYIVGMVPNNLMLLCVPPRIWLSFCTFAWGLLTLGMYKVTSFKHICA 130
Query: 169 LRTLLGVLEAFVSPIFVIMMNQYYKKSEHFGYIGVLYGCNGLGTVILACISYGLYHNL-G 227
+R + E+ ++ +YK+ E + G +G++ + ++ +L G
Sbjct: 131 IRFFQALFESCTFSGTHFVLGSWYKEDELPIRSAIFTGSGLVGSMFSGFMQTSIFTHLNG 190
Query: 228 SYTMEAYKVLFIIVGCLTIFNGLLILFIMPNTP----ADARF------LNDREKLAVLER 277
+ ++ LFII C+T+ + P P A ++F N++E R
Sbjct: 191 RNGLAGWRWLFIIDFCITLPIAIYGFIFFPGLPDQTSAVSKFSMTRYIFNEQELHYARRR 250
Query: 278 IRGNNQGFGSKTFKWHQMKECFMDMRTWLYFLIGISVAIPNGGISSFGSIILKGFGYSTE 337
+ ++ S W + W++ L+ + + N G +S + L
Sbjct: 251 LPARDE---STRLDWSTIPRVLKRWHWWMFSLVWV-LGGENLGFASNSTFALWLQNQKYT 306
Query: 338 KSLLMKAPIGACELVGLVILPLISYFISK-----RMIIAVFYLLVCVMSTCLL-AFSKNK 391
+ P G VG+V + ++SK ++VF LV V+ L+ A N
Sbjct: 307 LAQRNNYPSGIF-AVGIVSTLCSAVYMSKIPRARHWHVSVFISLVMVIVAVLIRADPLNP 365
Query: 392 NVALAGYYITGIAPVG 407
V + Y+ G+A G
Sbjct: 366 KVVFSAQYLGGVAYAG 381
>YAL067c [G] KOG2533 Permease of the major facilitator superfamily
Length = 593
Score = 58.5 bits (140), Expect = 2e-08
Identities = 88/443 (19%), Positives = 174/443 (38%), Gaps = 22/443 (4%)
Query: 63 EDRKVKRKIDMIVMPLFSFLYMIQFMDKTCISFAAVMGIQTDYKMVDTMYSWTTSCFYLG 122
+++K+ K+D+++ Y ++++D I+ A V G++ D T + +G
Sbjct: 127 KEKKLLIKLDVLLAFYSCIAYWVKYLDTVNINNAYVSGMKEDLGFQGNDLVHTQVMYTVG 186
Query: 123 -YLFASPFAAVALQKLPSMRTSAICIVIWGVIQCLHVTAKSYATFTLLRTLLGVLEAFVS 181
+F PF + L KLP + W ++ S +R +G EA
Sbjct: 187 NIIFQLPF-LIYLNKLPLNYVLPSLDLCWSLLTVGAAYVNSVPHLKAIRFFIGAFEAPSY 245
Query: 182 PIFVIMMNQYYKKSEHFGYIGVLYGCNGLGTVILACISYGLYHNL-GSYTMEAYKVLFII 240
+ + +YK E Y +G + I +Y +L G +E ++ FII
Sbjct: 246 LAYQYLFGSFYKHDEMVRRSAFYYLGQYIGILSAGGIQSAVYSSLNGVNGLEGWRWNFII 305
Query: 241 VGCLTIFNGLLILFIMPNTPAD--ARFLNDREKLAVLERIRGNNQG---FGSKTFKWHQM 295
+++ GL+ + +P P + + FL D E +R++ N G F +K F
Sbjct: 306 DAIVSVVVGLIGFYSLPGDPYNCYSIFLTDDEIRLARKRLKENQTGKSDFETKVFDIKLW 365
Query: 296 KECFMDMRTWLYFLIGISVAIPNGGISSFGSII-----LKGFGYSTEKSLLMKAPIGACE 350
K F D + +Y L ++ N S G+ + LK + L M P
Sbjct: 366 KTIFSDWK--IYILTLWNIFCWNDSNVSSGAYLLWLKSLKRYSIPKLNQLSMITP--GLG 421
Query: 351 LVGLVILPLISYFISKRMIIAVFYLLVCVMSTCLL-AFSKNKNVALAGYYIT--GIAPVG 407
+V L++ +I+ + R +F + ++ +L A+ + + + G A
Sbjct: 422 MVYLMLTGIIADKLHSRWFAIIFTQVFNIIGNSILAAWDVAEGAKWFAFMLQCFGWAMAP 481
Query: 408 IITITSCVASNTAGHTKKLTANAISLIGYSAGNIVGPQTFRSSDAPNYPKA-KAAVVGCY 466
++ T+ +T ++++ S+ + +++ +AP Y K +
Sbjct: 482 VLYSWQNDICRRDAQTRAITLVTMNIMAQSSTAWISVLVWKTEEAPRYLKGFTFTACSAF 541
Query: 467 CASIALMGLMSFLNVRENRRRDK 489
C SI ++ F R+ R K
Sbjct: 542 CLSIWTFVVLYFYK-RDERNNAK 563
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.325 0.139 0.415
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,821,866
Number of Sequences: 60738
Number of extensions: 1235129
Number of successful extensions: 3948
Number of sequences better than 1.0e-05: 18
Number of HSP's better than 0.0 without gapping: 13
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 3878
Number of HSP's gapped (non-prelim): 20
length of query: 521
length of database: 30,389,216
effective HSP length: 111
effective length of query: 410
effective length of database: 23,647,298
effective search space: 9695392180
effective search space used: 9695392180
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)