ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIV2867 good G KOG1369 Carbohydrate transport and metabolism Hexokinase
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIV2867 973371 974825 485
(485 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YGL253w [G] KOG1369 Hexokinase 749 0.0
YFR053c [G] KOG1369 Hexokinase 719 0.0
SPAC24H6.04 [G] KOG1369 Hexokinase 450 e-126
7301467 [G] KOG1369 Hexokinase 288 1e-77
YCL040w [G] KOG1369 Hexokinase 277 2e-74
At4g29130 [G] KOG1369 Hexokinase 272 7e-73
7303093 [G] KOG1369 Hexokinase 270 3e-72
At2g19860 [G] KOG1369 Hexokinase 269 6e-72
Hs15967159 [G] KOG1369 Hexokinase 268 1e-71
Hs4503951 [G] KOG1369 Hexokinase 268 1e-71
Hs15967161 [G] KOG1369 Hexokinase 267 2e-71
CE05628 [G] KOG1369 Hexokinase 265 1e-70
Hs15553127 [G] KOG1369 Hexokinase 265 1e-70
YDR516c [G] KOG1369 Hexokinase 264 2e-70
7291070 [G] KOG1369 Hexokinase 263 6e-70
Hs15991833 [G] KOG1369 Hexokinase 262 1e-69
Hs15991829 [G] KOG1369 Hexokinase 262 1e-69
Hs15991827 [G] KOG1369 Hexokinase 262 1e-69
Hs4504391 [G] KOG1369 Hexokinase 259 6e-69
Hs4504395 [G] KOG1369 Hexokinase 251 2e-66
SPAC4F8.07c [G] KOG1369 Hexokinase 243 4e-64
At1g50460 [G] KOG1369 Hexokinase 241 2e-63
At1g47840 [G] KOG1369 Hexokinase 239 5e-63
CE18823 [G] KOG1369 Hexokinase 239 7e-63
At3g20040 [G] KOG1369 Hexokinase 236 6e-62
CE25610 [G] KOG1369 Hexokinase 197 4e-50
Hs13376711 [G] KOG1369 Hexokinase 167 3e-41
At4g37840 [G] KOG1369 Hexokinase 140 4e-33
At1g47860_3 [G] KOG1369 Hexokinase 80 7e-15
ECU11g1540 [G] KOG1369 Hexokinase 71 4e-12
>YGL253w [G] KOG1369 Hexokinase
Length = 486
Score = 749 bits (1935), Expect = 0.0
Identities = 356/485 (73%), Positives = 417/485 (85%), Gaps = 1/485 (0%)
Query: 1 MVRLGPKKPPARKGSMADVPANLMEQIHGLETLFTVSSEKMRSIVKHFISELDKGLSKKG 60
MV LGPKKP ARKGSMADVP LM+QI E +FTV +E ++++ KHFISEL+KGLSKKG
Sbjct: 1 MVHLGPKKPQARKGSMADVPKELMQQIENFEKIFTVPTETLQAVTKHFISELEKGLSKKG 60
Query: 61 GNIPMIPGWVVEYPTGKETGDFLALDLGGTNLRVVLVKLGGNHDFDTTQNKYRLPDHLRT 120
GNIPMIPGWV+++PTGKE+GDFLA+DLGGTNLRVVLVKLGG+ FDTTQ+KYRLPD +RT
Sbjct: 61 GNIPMIPGWVMDFPTGKESGDFLAIDLGGTNLRVVLVKLGGDRTFDTTQSKYRLPDAMRT 120
Query: 121 GTS-EQLWSFIAKCLKEFVDEWYPDGVSEPLPLGFTFSYPASQKKINSGVLQRWTKGFDI 179
+ ++LW FIA LK F+DE +P G+SEP+PLGFTFS+PASQ KIN G+LQRWTKGFDI
Sbjct: 121 TQNPDELWEFIADSLKAFIDEQFPQGISEPIPLGFTFSFPASQNKINEGILQRWTKGFDI 180
Query: 180 EGVEGHDVVPMLQEQIEKLNIPINVVALINDTTGTLVASLYTDPQTKMGIIIGTGVNGAY 239
+E HDVVPMLQ+QI K NIPI VVALINDTTGTLVAS YTDP+TKMG+I GTGVNGAY
Sbjct: 181 PNIENHDVVPMLQKQITKRNIPIEVVALINDTTGTLVASYYTDPETKMGVIFGTGVNGAY 240
Query: 240 YDVVSGIEKLEGLLPEDIGPDSPMAINCEYGSFDNEHLVLPRTKYDVIIDEESPRPGQQA 299
YDV S IEKL+G L +DI P +PMAINCEYGSFDNEH+VLPRTKYD+ IDEESPRPGQQ
Sbjct: 241 YDVCSDIEKLQGKLSDDIPPSAPMAINCEYGSFDNEHVVLPRTKYDITIDEESPRPGQQT 300
Query: 300 FEKMTSGYYLGEIMRLVLLDLYDSGFIFKDQDISKLKEAYVMDTSYPSKIEDDPFENLED 359
FEKM+SGYYLGEI+RL L+D+Y GFIFK+QD+SK + +VMDTSYP++IE+DPFENLED
Sbjct: 301 FEKMSSGYYLGEILRLALMDMYKQGFIFKNQDLSKFDKPFVMDTSYPARIEEDPFENLED 360
Query: 360 TDDLFKTNLNIETTVVERKLIRKLAELVGTRAARLTVCGVSAICDKRGYKTAHIAADGSV 419
TDDLF+ I TTV ERKLIR+L+EL+G RAARL+VCG++AIC KRGYKT HIAADGSV
Sbjct: 361 TDDLFQNEFGINTTVQERKLIRRLSELIGARAARLSVCGIAAICQKRGYKTGHIAADGSV 420
Query: 420 FNRYPGYKEKAAQALKDIYNWDVEKMEDHPIQLVAAEDGSGVGAAIIACLTQKRLAAGKS 479
+NRYPG+KEKAA ALKDIY W ++D+PI++V AEDGSG GAA+IA L QKR+A GKS
Sbjct: 421 YNRYPGFKEKAANALKDIYGWTQTSLDDYPIKIVPAEDGSGAGAAVIAALAQKRIAEGKS 480
Query: 480 VGIKG 484
VGI G
Sbjct: 481 VGIIG 485
>YFR053c [G] KOG1369 Hexokinase
Length = 485
Score = 719 bits (1856), Expect = 0.0
Identities = 345/485 (71%), Positives = 411/485 (84%), Gaps = 2/485 (0%)
Query: 1 MVRLGPKKPPARKGSMADVPANLMEQIHGLETLFTVSSEKMRSIVKHFISELDKGLSKKG 60
MV LGPKKP ARKGSMADVP LM++IH LE +FTV SE +R +VKHFI EL+KGL+KKG
Sbjct: 1 MVHLGPKKPQARKGSMADVPKELMDEIHQLEDMFTVDSETLRKVVKHFIDELNKGLTKKG 60
Query: 61 GNIPMIPGWVVEYPTGKETGDFLALDLGGTNLRVVLVKLGGNHDFDTTQNKYRLPDHLRT 120
GNIPMIPGWV+E+PTGKE+G++LA+DLGGTNLRVVLVKL GNH FDTTQ+KY+LP +RT
Sbjct: 61 GNIPMIPGWVMEFPTGKESGNYLAIDLGGTNLRVVLVKLSGNHTFDTTQSKYKLPHDMRT 120
Query: 121 GT-SEQLWSFIAKCLKEFVDEWYPDGVSEPLPLGFTFSYPASQKKINSGVLQRWTKGFDI 179
E+LWSFIA LK+F+ E + LPLGFTFSYPASQ KIN G+LQRWTKGFDI
Sbjct: 121 TKHQEELWSFIADSLKDFMVEQELLNTKDTLPLGFTFSYPASQNKINEGILQRWTKGFDI 180
Query: 180 EGVEGHDVVPMLQEQIEKLNIPINVVALINDTTGTLVASLYTDPQTKMGIIIGTGVNGAY 239
VEGHDVVP+LQ +I K +PI +VALINDT GTL+AS YTDP+TKMG+I GTGVNGA+
Sbjct: 181 PNVEGHDVVPLLQNEISKRELPIEIVALINDTVGTLIASYYTDPETKMGVIFGTGVNGAF 240
Query: 240 YDVVSGIEKLEGLLPEDIGPDSPMAINCEYGSFDNEHLVLPRTKYDVIIDEESPRPGQQA 299
YDVVS IEKLEG L +DI +SPMAINCEYGSFDNEHLVLPRTKYDV +DE+SPRPGQQA
Sbjct: 241 YDVVSDIEKLEGKLADDIPSNSPMAINCEYGSFDNEHLVLPRTKYDVAVDEQSPRPGQQA 300
Query: 300 FEKMTSGYYLGEIMRLVLLDLYDSGFIFKDQDISKLKEAYVMDTSYPSKIEDDPFENLED 359
FEKMTSGYYLGE++RLVLL+L + G + KDQD+SKLK+ Y+MDTSYP++IEDDPFENLED
Sbjct: 301 FEKMTSGYYLGELLRLVLLELNEKGLMLKDQDLSKLKQPYIMDTSYPARIEDDPFENLED 360
Query: 360 TDDLFKTNLNIETTVVERKLIRKLAELVGTRAARLTVCGVSAICDKRGYKTAHIAADGSV 419
TDD+F+ + ++TT+ ERKLIR+L EL+GTRAARL VCG++AIC KRGYKT HIAADGSV
Sbjct: 361 TDDIFQKDFGVKTTLPERKLIRRLCELIGTRAARLAVCGIAAICQKRGYKTGHIAADGSV 420
Query: 420 FNRYPGYKEKAAQALKDIYNWDVEKMEDHPIQLVAAEDGSGVGAAIIACLTQKRLAAGKS 479
+N+YPG+KE AA+ L+DIY W + +D PI +V AEDGSG GAA+IA L++KR+A GKS
Sbjct: 421 YNKYPGFKEAAAKGLRDIYGWTGDASKD-PITIVPAEDGSGAGAAVIAALSEKRIAEGKS 479
Query: 480 VGIKG 484
+GI G
Sbjct: 480 LGIIG 484
>SPAC24H6.04 [G] KOG1369 Hexokinase
Length = 484
Score = 450 bits (1158), Expect = e-126
Identities = 229/470 (48%), Positives = 313/470 (65%), Gaps = 13/470 (2%)
Query: 6 PKKPPARKGSMADVPANLMEQIHGLETLFTVSSEKMRSIVKHFISELDKGLSKKGGNIPM 65
P + P+RKGS + L + + LE FT+ +E + + F+SEL KGL+ G++PM
Sbjct: 10 PSRTPSRKGSNIKLNKTLQDHLDELEEQFTIPTELLHRVTDRFVSELYKGLTTNPGDVPM 69
Query: 66 IPGWVVEYPTGKETGDFLALDLGGTNLRVVLVKLGGNHDFDTTQNKYRLPDHLRTGTSEQ 125
+P W++ P G E G +LALDLGGTNLRV V++ GN FD TQ+KYRLP L+ GT E
Sbjct: 70 VPTWIIGTPDGNEHGSYLALDLGGTNLRVCAVEVQGNGKFDITQSKYRLPQELKVGTREA 129
Query: 126 LWSFIAKCLKEFVDEWYPDGVSEPLPLGFTFSYPASQKKINSGVLQRWTKGFDIEGVEGH 185
L+ +IA C+K+FV+E +P G S+ L +GFTFSYP Q+ IN L WTKGFDI+GVEG
Sbjct: 130 LFDYIADCIKKFVEEVHP-GKSQNLEIGFTFSYPCVQRSINDASLVAWTKGFDIDGVEGE 188
Query: 186 DVVPMLQEQIEKL---NIPINVVALINDTTGTLVASLYTDPQTKMGIIIGTGVNGAYYDV 242
V P+L ++++ N+ +N A+++DTTGTLVAS Y P T++G+I GTG N Y +
Sbjct: 189 SVGPLLSAALKRVGCNNVRLN--AILSDTTGTLVASNYASPGTEIGVIFGTGCNACYIEK 246
Query: 243 VSGIEKLEGLLPEDIGPDSPMAINCEYGSFDNEHLVLPRTKYDVIIDEESPRPGQQAFEK 302
S I KL D D M INCE+ FDN+H+VLPRTKYDV IDEESPRPG Q +EK
Sbjct: 247 FSEIPKLHKY---DFPEDMNMIINCEWCDFDNQHVVLPRTKYDVAIDEESPRPGLQTYEK 303
Query: 303 MTSGYYLGEIMRLVLLDLYDSGFIFKDQDISKLKEAYVMDTSYPSKIEDDPFENLEDTDD 362
M +G YLG+I+R +LLDLY+ G +F QD++K+++ MDTS S IE DPFENL++T
Sbjct: 304 MIAGCYLGDILRRILLDLYEQGALFNGQDVTKIRDPLAMDTSVLSAIEVDPFENLDETQT 363
Query: 363 LFKTNLNIETTVVERKLIRKLAELVGTRAARLTVCGVSAICDKRGYKTAHIAADGSVFNR 422
LF+ ++TT ER+ IR+ EL+GTR+ARL+ CGV A+ K + + DGSV+N
Sbjct: 364 LFEETYGLKTTEEERQFIRRACELIGTRSARLSACGVCALVRKMNKPSMIVGTDGSVYNL 423
Query: 423 YPGYKEKAAQALKDIYNWDVEKMEDHPIQLVAAEDGSGVGAAIIACLTQK 472
YP +K++ AQA KDI ++ + + AEDGSGVGAA+++ L K
Sbjct: 424 YPRFKDRLAQAFKDILGEEI----GSKVVTIPAEDGSGVGAALVSALEAK 469
>7301467 [G] KOG1369 Hexokinase
Length = 907
Score = 288 bits (737), Expect = 1e-77
Identities = 167/455 (36%), Positives = 252/455 (54%), Gaps = 18/455 (3%)
Query: 19 VPANLMEQIHGLETLFTVSSEKMRSIVKHFISELDKGLSKKG---GNIPMIPGWVVEYPT 75
+P+ + +I F + EKM +V+ E+ GL+K I V + PT
Sbjct: 455 MPSLVNTEIEAAVKGFLIDQEKMTEVVERMTKEIKMGLAKDTHARAVIKCFVSHVQDLPT 514
Query: 76 GKETGDFLALDLGGTNLRVVLVKLGGNHDFDTTQNKYRLPDHLRTGTSEQLWSFIAKCLK 135
GKE G +LALDLGG+N RV+LV L N D +T Y P L +G+ + L+ F+A+CL
Sbjct: 515 GKERGKYLALDLGGSNFRVLLVNLISNSDVETMSKGYNFPQTLMSGSGKALFDFLAECLS 574
Query: 136 EFVDEWYPDGV-SEPLPLGFTFSYPASQKKINSGVLQRWTKGFDIEGVEGHDVVPMLQEQ 194
EF + G+ +E L LGFTFS+P Q+ ++ G+L WTKGF EGV G +VV +LQE
Sbjct: 575 EFC---HSHGLENESLALGFTFSFPLQQQGLSKGILVAWTKGFSCEGVVGKNVVSLLQEA 631
Query: 195 IEKL-NIPINVVALINDTTGTLVASLYTDPQTKMGIIIGTGVNGAYYDVVSGIEKLEGLL 253
I++ ++ IN VA++NDT GTL++ + P ++G+I+GTG N Y + E EG
Sbjct: 632 IDRRGDLKINTVAILNDTVGTLMSCAFYHPNCRIGLIVGTGSNACYVEKTVNAECFEGY- 690
Query: 254 PEDIGPDSPMAINCEYGSF-DNEHLVLPRTKYDVIIDEESPRPGQQAFEKMTSGYYLGEI 312
P M INCE+G+F DN L RT YD +D+ +P PG+Q FEK SG Y+GE+
Sbjct: 691 --QTSPKPSMIINCEWGAFGDNGVLEFVRTSYDKAVDKVTPNPGKQTFEKCISGMYMGEL 748
Query: 313 MRLVLLDLYDSGFIFKDQDISKLKEAYVMDTSYPSKIEDDPFENLEDTDDLFKTNLNIET 372
+RLV+ D+ GF+F K++E + T+Y S +E D + + + +
Sbjct: 749 VRLVITDMIAKGFMFHGIISEKIQERWSFKTAYISDVESDAPGEYRNCNKVLSELGILGC 808
Query: 373 TVVERKLIRKLAELVGTRAARLTVCGVSAICDKRGYKTAHIAADGSVFNRYPGYKEKAAQ 432
+++ +R + E V +R+A+L CG+ I +K I DGSV+ +P Y +
Sbjct: 809 QEPDKEALRYICEAVSSRSAKLCACGLVTIINKMNINEVAIGIDGSVYRFHPKYHDMLQY 868
Query: 433 ALKDIYNWDVEKMEDHPIQLVAAEDGSGVGAAIIA 467
+K + V+ +LV +EDGSG GAA++A
Sbjct: 869 HMKKLLKPGVK------FELVVSEDGSGRGAALVA 897
Score = 186 bits (472), Expect = 7e-47
Identities = 132/459 (28%), Positives = 220/459 (47%), Gaps = 30/459 (6%)
Query: 20 PANLMEQIHGLETLFTVSSEKMRSIVKHFISELDKGLSKKGGNIPMIP---GWVVEYPTG 76
P +++ + LF S + + I E+ GLS+ + +P +V + PTG
Sbjct: 7 PEEDFPEVYKVCKLFNPSIDDLEKIKNAMDREITMGLSRDHHDRSTVPCHLSYVQDLPTG 66
Query: 77 KETGDFLALDLGGTNLRVVLVKLGGNHDFDTTQNKYRLPDHLRTGTSEQLWSFIAKCLKE 136
+E G FLAL++ TN R++LVK D T+ +P + G ++++F+A +
Sbjct: 67 RERGQFLALEMMPTNCRIMLVKFSSERDIYTSSKCVIMPHTVAAGRGTEVFTFLATSIAN 126
Query: 137 FVDEWYPDGVSEPLPLGFTFSYPASQKKINSGVLQRWTKGFDIEGVEGHDVVPMLQEQIE 196
FV E D + LPLG F++ + ++ G+L WTK F +G G DVV +L++ +
Sbjct: 127 FVKEKKVD--KDNLPLGIAFAFTLKKLALDVGILVSWTKEFGAQGAIGKDVVQLLRDALA 184
Query: 197 KL-NIPINVVALINDTTGTLVASLYTDPQTKMGIIIGTGVNGAYYDVVSGIEKLEGLLPE 255
K I ++V+ +IN G+L+A + P T++G+I+G+ N Y + V E EG
Sbjct: 185 KFPEISVDVMGIINVGAGSLLALCWAQPDTRIGLIMGSIANSCYVERVERCETYEGDEYR 244
Query: 256 DIGPDSPMAINCEYGSF-DNEHLVLPRTKYDVIIDEESPRPGQQAFEKMTSGYYLGEIMR 314
+ M IN ++ F D L R +YD +D ES PG + +EK + +GE++R
Sbjct: 245 KL-----MIINSDWAHFGDTGQLDFIRNEYDRQLDTESINPGTRIYEKFSGALCMGELVR 299
Query: 315 LVLLDLYDSGFIFKDQDISKLKEAYVMDTSYPSKIEDDP---FENLEDTDDLFKTNLNIE 371
+++L L SG IF + + + +D +I DP + ++ D F+ E
Sbjct: 300 IIVLRLMKSGAIFAEDRRDYIGIQWKLDMVSLIEIVSDPPGVYTKAQEVMDKFRIRHCKE 359
Query: 372 TTVVERKLIRKLAELVGTRAARLTVCGVSAICDKRGYKTAHIAADGSVFNRYPGYK---E 428
+ K I + V RAA L GVS + D+ IA DG ++ +P +
Sbjct: 360 RDLAALKYI---CDTVTNRAAMLVASGVSCLIDRMRLPQISIAVDGGIYRLHPTFSTVLN 416
Query: 429 KAAQALKDIYNWDVEKMEDHPIQLVAAEDGSGVGAAIIA 467
K + L D ++ + V +D GVGAAI+A
Sbjct: 417 KYTRLLAD---------PNYNFEFVITQDSCGVGAAIMA 446
>YCL040w [G] KOG1369 Hexokinase
Length = 500
Score = 277 bits (709), Expect = 2e-74
Identities = 181/476 (38%), Positives = 255/476 (53%), Gaps = 45/476 (9%)
Query: 34 FTVSSEKMRSIVKHFISELDKGLS--KKGGNI------PMIPGWVVEYPTGKETGDFLAL 85
F V+ EK+ + +FI +++KGL+ K+G + PMIP +V P G E G LA
Sbjct: 25 FEVTPEKLDELTAYFIEQMEKGLAPPKEGHTLASDKGLPMIPAFVTGSPNGTERGVLLAA 84
Query: 86 DLGGTNLRVVLVKLGGNHDFDTTQNKYRLPDHL---RTGTSEQLWSFIAKCLKEFVDEWY 142
DLGGTN R+ V L G+H F Q K ++PD L TS+ L+ F+A+ F+ +++
Sbjct: 85 DLGGTNFRICSVNLHGDHTFSMEQMKSKIPDDLLDDENVTSDDLFGFLARRTLAFMKKYH 144
Query: 143 PDGVSE-----PLPLGFTFSYPASQKKINSGVLQRWTKGFDIEGVEGHDVVPMLQEQIEK 197
PD +++ P+ LGFTFSYP Q +NSG L RWTKGF I G DVV + QEQ+
Sbjct: 145 PDELAKGKDAKPMKLGFTFSYPVDQTSLNSGTLIRWTKGFRIADTVGKDVVQLYQEQLSA 204
Query: 198 LNIP-INVVALINDTTGTLVASLYTDPQTK-----------MGIIIGTGVNGAYYDVVSG 245
+P I VVAL NDT GT ++ YT T +G I GTG NG Y + ++
Sbjct: 205 QGMPMIKVVALTNDTVGTYLSHCYTSDNTDSMTSGEISEPVIGCIFGTGTNGCYMEEINK 264
Query: 246 IEKLEGLLPEDIGPD--SPMAINCEYGSFDNEHLVLPRTKYDVIIDEE-SPRPGQQAFEK 302
I KL L + + + + M IN E+GSFDNE LP TKYDV+ID++ S PG FEK
Sbjct: 265 ITKLPQELRDKLIKEGKTHMIINVEWGSFDNELKHLPTTKYDVVIDQKLSTNPGFHLFEK 324
Query: 303 MTSGYYLGEIMRLVLLDLYDSGFIF-----KDQDISKLKEAYVMDTSYPSKIEDDPFENL 357
SG +LGE++R +L+DL+ G + K+Q L + + + S IE D L
Sbjct: 325 RVSGMFLGEVLRNILVDLHSQGLLLQQYRSKEQLPRHLTTPFQLSSEVLSHIEIDDSTGL 384
Query: 358 EDTDDLFKTNLNIETTVVERKLIRKLAELVGTRAARLTVCGVSAI------CDKRGYKTA 411
+T+ +L + TT ER I+KL + R+A L ++AI +KR +
Sbjct: 385 RETELSLLQSLRLPTTPTERVQIQKLVRAISRRSAYLAAVPLAAILIKTNALNKRYHGEV 444
Query: 412 HIAADGSVFNRYPGYKEKAAQALKDIYNWDVEKMEDHPIQLVAAEDGSGVGAAIIA 467
I DGSV YPG++ AL + + + L A+DGSGVGAA+ A
Sbjct: 445 EIGCDGSVVEYYPGFRSMLRHALA---LSPLGAEGERKVHLKIAKDGSGVGAALCA 497
>At4g29130 [G] KOG1369 Hexokinase
Length = 496
Score = 272 bits (696), Expect = 7e-73
Identities = 165/445 (37%), Positives = 245/445 (54%), Gaps = 29/445 (6%)
Query: 40 KMRSIVKHFISELDKGLSKKGGN-IPMIPGWVVEYPTGKETGDFLALDLGGTNLRVVLVK 98
K+R + E+ GL+ GG+ + M+ +V P+G E G F ALDLGGTN RV+ V
Sbjct: 54 KLRQVADAMTVEMHAGLASDGGSKLKMLISYVDNLPSGDEKGLFYALDLGGTNFRVMRVL 113
Query: 99 LGGNHDFDTTQN--KYRLPDHLRTGTSEQLWSFIAKCLKEFV-----DEWYPDGVSEPLP 151
LGG + Q + +P HL TG S++L++FIA+ L +FV D P+G L
Sbjct: 114 LGGKQERVVKQEFEEVSIPPHLMTGGSDELFNFIAEALAKFVATECEDFHLPEGRQREL- 172
Query: 152 LGFTFSYPASQKKINSGVLQRWTKGFDIEGVEGHDVVPMLQEQIEKLNIPINVVALINDT 211
GFTFS+P Q ++SG L +WTKGF IE G DVV L + +E++ + + + AL+NDT
Sbjct: 173 -GFTFSFPVKQTSLSSGSLIKWTKGFSIEEAVGQDVVGALNKALERVGLDMRIAALVNDT 231
Query: 212 TGTLVASLYTDPQTKMGIIIGTGVNGAYYDVVSGIEKLEGLLPEDIGPDSPMAINCEYGS 271
GTL Y +P +I+GTG N AY + + I K GLLP+ M IN E+G+
Sbjct: 232 VGTLAGGRYYNPDVVAAVILGTGTNAAYVERATAIPKWHGLLPK----SGEMVINMEWGN 287
Query: 272 FDNEHLVLPRTKYDVIIDEESPRPGQQAFEKMTSGYYLGEIMRLVLLDLYDSGFIFKDQD 331
F + H LP T++D +D ES PG+Q EK+ SG YLGEI+R VLL + + F D
Sbjct: 288 FRSSH--LPLTEFDHTLDFESLNPGEQILEKIISGMYLGEILRRVLLKMAEDAAFFGDTV 345
Query: 332 ISKLKEAYVMDTSYPSKIEDDPFENLEDTDDLFKTNLNIETTVVE-RKLIRKLAELVGTR 390
SKL+ +++ T + S + +D +L+ K L + TT ++ RK++ L ++ TR
Sbjct: 346 PSKLRIPFIIRTPHMSAMHNDTSPDLKIVGSKIKDILEVPTTSLKMRKVVISLCNIIATR 405
Query: 391 AARLTVCGVSAICDKRGYKTAH--------IAADGSVFNRYPGYKEKAAQALKDIYNWDV 442
ARL+ G+ I K G T IA DG +F Y + E +LK++ +
Sbjct: 406 GARLSAAGIYGILKKLGRDTTKDEEVQKSVIAMDGGLFEHYTQFSECMESSLKELLGDEA 465
Query: 443 EKMEDHPIQLVAAEDGSGVGAAIIA 467
+++ + DGSG+GAA++A
Sbjct: 466 ----SGSVEVTHSNDGSGIGAALLA 486
>7303093 [G] KOG1369 Hexokinase
Length = 454
Score = 270 bits (691), Expect = 3e-72
Identities = 169/459 (36%), Positives = 248/459 (53%), Gaps = 23/459 (5%)
Query: 26 QIHGLETLFTVSSEKMRSIVKHFISELDKGLSKKG---GNIPMIPGWVVEYPTGKETGDF 82
++ L F +S +++ + F E+ +GL + N+ P +V + PTG E G +
Sbjct: 5 EVRELMQPFVLSDYQVQEVYSRFCLEVARGLKRSTHPQANVKCFPTYVQDLPTGDEMGKY 64
Query: 83 LALDLGGTNLRVVLVKLGGNHDFDTTQNKYRLPDHLRTGTSEQLWSFIAKCLKEFVDEWY 142
LALDLGGTN RV+LV L G+HD Y +P L G L+ IA CL +FV++
Sbjct: 65 LALDLGGTNFRVLLVSLKGHHDATVDSQIYAVPKDLMVGPGVDLFDHIAGCLAKFVEK-- 122
Query: 143 PDGVSEPLPLGFTFSYPASQKKINSGVLQRWTKGFDIEGVEGHDVVPMLQEQIEKL-NIP 201
D + LPLGFTFS+P Q + G+L RWTKGFD GVEG DV ML E I++ +
Sbjct: 123 HDMKTAYLPLGFTFSFPCVQLGLKEGILVRWTKGFDCAGVEGEDVGRMLHEAIQRRGDAD 182
Query: 202 INVVALINDTTGTLVASLYTDPQTKMGIIIGTGVNGAYYDVVSGIEKLEGLLPEDIGPDS 261
I VVA++NDTTGTL++ + + ++G+I+GTG N Y V +E ++ L +
Sbjct: 183 IAVVAILNDTTGTLMSCAHRNADCRVGVIVGTGCNACY---VEDVENVDLLRADFKKTKR 239
Query: 262 PMAINCEYGSF-DNEHLVLPRTKYDVIIDEESPRPGQQAFEKMTSGYYLGEIMRLVLLDL 320
+ +N E+G+F + L RT+YD +DE+S +Q FEKMT+G YLG ++RLVLL
Sbjct: 240 SVIVNAEWGAFGEGGQLDFVRTEYDREVDEKSLNRSEQLFEKMTAGMYLGNLVRLVLLRA 299
Query: 321 YDSGFIFKDQD-----ISKL-KEAYVMDTSYPSKIEDDPFENLEDTDDLFKTNLNIETTV 374
+ IFK S L + V +T Y S+IEDD F T + K +E
Sbjct: 300 LERKLIFKQSSRRPEFASVLQRNEEVFETRYISEIEDDSFPEFASTRKIVKNLFGLEKAS 359
Query: 375 VER-KLIRKLAELVGTRAARLTVCGVSAICDKRGYKTAHIAADGSVFNRYPGYKEKAAQA 433
VE + +R + E V RAA L GVS + ++ + + DGSV+ +P + Q
Sbjct: 360 VEDCQTLRYICECVAKRAATLVAIGVSGLVNRTSNRRVIVGMDGSVYRYHPKFDAYMRQT 419
Query: 434 LKDIYNWDVEKMEDHPIQLVAAEDGSGVGAAIIACLTQK 472
L+ + D E ++ +EDGSG GAA++A + K
Sbjct: 420 LQKLVKADKE------WDIMLSEDGSGRGAALVAAVASK 452
>At2g19860 [G] KOG1369 Hexokinase
Length = 502
Score = 269 bits (688), Expect = 6e-72
Identities = 168/464 (36%), Positives = 250/464 (53%), Gaps = 29/464 (6%)
Query: 21 ANLMEQIHGLETLFTVSSEKMRSIVKHFISELDKGLSKKGGN-IPMIPGWVVEYPTGKET 79
A ++E + E K+R + E+ GL+ +GG+ + M+ +V P+G ET
Sbjct: 35 ARVIEILKAFEEDCATPIAKLRQVADAMTVEMHAGLASEGGSKLKMLISYVDNLPSGDET 94
Query: 80 GDFLALDLGGTNLRVVLVKLGGNHDFDTTQN--KYRLPDHLRTGTSEQLWSFIAKCLKEF 137
G F ALDLGGTN RV+ V LGG HD + + +P HL TG S +L+ FI L +F
Sbjct: 95 GFFYALDLGGTNFRVMRVLLGGKHDRVVKREFKEESIPPHLMTGKSHELFDFIVDVLAKF 154
Query: 138 V-----DEWYPDGVSEPLPLGFTFSYPASQKKINSGVLQRWTKGFDIEGVEGHDVVPMLQ 192
V D P G L GFTFS+P Q ++SG L WTKGF I+ DVV L
Sbjct: 155 VATEGEDFHLPPGRQREL--GFTFSFPVKQLSLSSGTLINWTKGFSIDDTVDKDVVGELV 212
Query: 193 EQIEKLNIPINVVALINDTTGTLVASLYTDPQTKMGIIIGTGVNGAYYDVVSGIEKLEGL 252
+ +E++ + + V AL+NDT GTL YT+P + +I+GTG N AY + I K GL
Sbjct: 213 KAMERVGLDMLVAALVNDTIGTLAGGRYTNPDVVVAVILGTGTNAAYVERAHAIPKWHGL 272
Query: 253 LPEDIGPDSPMAINCEYGSFDNEHLVLPRTKYDVIIDEESPRPGQQAFEKMTSGYYLGEI 312
LP+ M IN E+G+F + H LP T+YD +D +S PG+Q EK+ SG YLGEI
Sbjct: 273 LPK----SGEMVINMEWGNFRSSH--LPLTEYDHSLDVDSLNPGEQILEKIISGMYLGEI 326
Query: 313 MRLVLLDLYDSGFIFKDQDISKLKEAYVMDTSYPSKIEDDPFENLEDTDDLFKTNLNIET 372
+R VLL + + F D KLK +++ T S + D +L+ K L ++T
Sbjct: 327 LRRVLLKMAEEAAFFGDIVPPKLKIPFIIRTPNMSAMHSDTSPDLKVVGSKLKDILEVQT 386
Query: 373 TVVE-RKLIRKLAELVGTRAARLTVCGVSAICDKRG--------YKTAHIAADGSVFNRY 423
+ ++ RK++ L ++ +R ARL+ G+ I K G + + IA DG +F Y
Sbjct: 387 SSLKMRKVVISLCNIIASRGARLSAAGIYGILKKIGRDATKDGEAQKSVIAMDGGLFEHY 446
Query: 424 PGYKEKAAQALKDIYNWDVEKMEDHPIQLVAAEDGSGVGAAIIA 467
+ E +LK++ +V + ++++ + DGSGVGAA++A
Sbjct: 447 TQFSESMKSSLKELLGDEVSE----SVEVILSNDGSGVGAALLA 486
>Hs15967159 [G] KOG1369 Hexokinase
Length = 466
Score = 268 bits (686), Expect = 1e-71
Identities = 153/474 (32%), Positives = 265/474 (55%), Gaps = 36/474 (7%)
Query: 15 SMADVPANLMEQIHGLETLFTVSSEKMRSIVKHFISELDKGL---SKKGGNIPMIPGWVV 71
S A L+EQI F + E ++ +++ E+D+GL + + ++ M+P +V
Sbjct: 8 SQAQTALTLVEQILAE---FQLQEEDLKKVMRRMQKEMDRGLRLETHEEASVKMLPTYVR 64
Query: 72 EYPTGKETGDFLALDLGGTNLRVVLVKLG----GNHDFDTTQNKYRLPDHLRTGTSEQLW 127
P G E GDFL+LDLGGTN RV+LVK+G G T Y +P+ TGT+E L+
Sbjct: 65 STPEGSEVGDFLSLDLGGTNFRVMLVKVGEGEEGQWSVKTKHQMYSIPEDAMTGTAEMLF 124
Query: 128 SFIAKCLKEFVDEWYPDGVSEPLPLGFTFSYPASQKKINSGVLQRWTKGFDIEGVEGHDV 187
+I++C+ +F+D+ + LPLGFTFS+P + I+ G+L WTKGF G EG++V
Sbjct: 125 DYISECISDFLDKHQMK--HKKLPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAEGNNV 182
Query: 188 VPMLQEQIEKL-NIPINVVALINDTTGTLVASLYTDPQTKMGIIIGTGVNGAYYDVVSGI 246
V +L++ I++ + ++VVA++NDT T+++ Y D Q ++G+I+GTG N Y + + +
Sbjct: 183 VGLLRDAIKRRGDFEMDVVAMVNDTVATMISCYYEDHQCEVGMIVGTGCNACYMEEMQNV 242
Query: 247 EKLEGLLPEDIGPDSPMAINCEYGSF-DNEHLVLPRTKYDVIIDEESPRPGQQAFEKMTS 305
E +EG + M +N E+G+F D+ L +YD ++DE S PGQQ +EK+
Sbjct: 243 ELVEG-------DEGRMCVNTEWGAFGDSGELDEFLLEYDRLVDESSANPGQQLYEKLIG 295
Query: 306 GYYLGEIMRLVLLDLYDSGFIFKDQDISKLKEAYVMDTSYPSKIEDDPFENLEDTDDLFK 365
G Y+GE++RLVLL L D +F + +L+ +T + S++E D + + + L
Sbjct: 296 GKYMGELVRLVLLRLVDENLLFHGEASEQLRTRGAFETRFVSQVESDTGDRKQIYNIL-- 353
Query: 366 TNLNIETTVVERKLIRKLAELVGTRAARLTVCGVSAICDKRGYKTAH------IAADGSV 419
+ L + + + ++R+ E V TRAA + G++ + ++ + + DGSV
Sbjct: 354 STLGLRPSTTDCDIVRRACESVSTRAAHMCSAGLAGVINRMRESRSEDVMRITVGVDGSV 413
Query: 420 FNRYPGYKEKAAQALKDIYNWDVEKMEDHPIQLVAAEDGSGVGAAIIACLTQKR 473
+ +P +KE+ +++ + I + +E+GSG GAA+++ + K+
Sbjct: 414 YKLHPSFKERFHASVRRL-------TPSCEITFIESEEGSGRGAALVSAVACKK 460
>Hs4503951 [G] KOG1369 Hexokinase
Length = 465
Score = 268 bits (685), Expect = 1e-71
Identities = 150/472 (31%), Positives = 265/472 (55%), Gaps = 33/472 (6%)
Query: 17 ADVPANLMEQIHGLETLFTVSSEKMRSIVKHFISELDKGL---SKKGGNIPMIPGWVVEY 73
A + A E++ + F + E ++ +++ E+D+GL + + ++ M+P +V
Sbjct: 6 ARMEAAKKEKVEQILAEFQLQEEDLKKVMRRMQKEMDRGLRLETHEEASVKMLPTYVRST 65
Query: 74 PTGKETGDFLALDLGGTNLRVVLVKLG----GNHDFDTTQNKYRLPDHLRTGTSEQLWSF 129
P G E GDFL+LDLGGTN RV+LVK+G G T Y +P+ TGT+E L+ +
Sbjct: 66 PEGSEVGDFLSLDLGGTNFRVMLVKVGEGEEGQWSVKTKHQMYSIPEDAMTGTAEMLFDY 125
Query: 130 IAKCLKEFVDEWYPDGVSEPLPLGFTFSYPASQKKINSGVLQRWTKGFDIEGVEGHDVVP 189
I++C+ +F+D+ + LPLGFTFS+P + I+ G+L WTKGF G EG++VV
Sbjct: 126 ISECISDFLDKHQMK--HKKLPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAEGNNVVG 183
Query: 190 MLQEQIEKL-NIPINVVALINDTTGTLVASLYTDPQTKMGIIIGTGVNGAYYDVVSGIEK 248
+L++ I++ + ++VVA++NDT T+++ Y D Q ++G+I+GTG N Y + + +E
Sbjct: 184 LLRDAIKRRGDFEMDVVAMVNDTVATMISCYYEDHQCEVGMIVGTGCNACYMEEMQNVEL 243
Query: 249 LEGLLPEDIGPDSPMAINCEYGSF-DNEHLVLPRTKYDVIIDEESPRPGQQAFEKMTSGY 307
+EG + M +N E+G+F D+ L +YD ++DE S PGQQ +EK+ G
Sbjct: 244 VEG-------DEGRMCVNTEWGAFGDSGELDEFLLEYDRLVDESSANPGQQLYEKLIGGK 296
Query: 308 YLGEIMRLVLLDLYDSGFIFKDQDISKLKEAYVMDTSYPSKIEDDPFENLEDTDDLFKTN 367
Y+GE++RLVLL L D +F + +L+ +T + S++E D + + + L +
Sbjct: 297 YMGELVRLVLLRLVDENLLFHGEASEQLRTRGAFETRFVSQVESDTGDRKQIYNIL--ST 354
Query: 368 LNIETTVVERKLIRKLAELVGTRAARLTVCGVSAICDKRGYKTAH------IAADGSVFN 421
L + + + ++R+ E V TRAA + G++ + ++ + + DGSV+
Sbjct: 355 LGLRPSTTDCDIVRRACESVSTRAAHMCSAGLAGVINRMRESRSEDVMRITVGVDGSVYK 414
Query: 422 RYPGYKEKAAQALKDIYNWDVEKMEDHPIQLVAAEDGSGVGAAIIACLTQKR 473
+P +KE+ +++ + I + +E+GSG GAA+++ + K+
Sbjct: 415 LHPSFKERFHASVRRL-------TPSCEITFIESEEGSGRGAALVSAVACKK 459
>Hs15967161 [G] KOG1369 Hexokinase
Length = 464
Score = 267 bits (683), Expect = 2e-71
Identities = 148/463 (31%), Positives = 261/463 (55%), Gaps = 33/463 (7%)
Query: 26 QIHGLETLFTVSSEKMRSIVKHFISELDKGL---SKKGGNIPMIPGWVVEYPTGKETGDF 82
Q+ + F + E ++ +++ E+D+GL + + ++ M+P +V P G E GDF
Sbjct: 14 QVEQILAEFQLQEEDLKKVMRRMQKEMDRGLRLETHEEASVKMLPTYVRSTPEGSEVGDF 73
Query: 83 LALDLGGTNLRVVLVKLG----GNHDFDTTQNKYRLPDHLRTGTSEQLWSFIAKCLKEFV 138
L+LDLGGTN RV+LVK+G G T Y +P+ TGT+E L+ +I++C+ +F+
Sbjct: 74 LSLDLGGTNFRVMLVKVGEGEEGQWSVKTKHQMYSIPEDAMTGTAEMLFDYISECISDFL 133
Query: 139 DEWYPDGVSEPLPLGFTFSYPASQKKINSGVLQRWTKGFDIEGVEGHDVVPMLQEQIEKL 198
D+ + LPLGFTFS+P + I+ G+L WTKGF G EG++VV +L++ I++
Sbjct: 134 DKHQMK--HKKLPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAEGNNVVGLLRDAIKRR 191
Query: 199 -NIPINVVALINDTTGTLVASLYTDPQTKMGIIIGTGVNGAYYDVVSGIEKLEGLLPEDI 257
+ ++VVA++NDT T+++ Y D Q ++G+I+GTG N Y + + +E +EG
Sbjct: 192 GDFEMDVVAMVNDTVATMISCYYEDHQCEVGMIVGTGCNACYMEEMQNVELVEG------ 245
Query: 258 GPDSPMAINCEYGSF-DNEHLVLPRTKYDVIIDEESPRPGQQAFEKMTSGYYLGEIMRLV 316
+ M +N E+G+F D+ L +YD ++DE S PGQQ +EK+ G Y+GE++RLV
Sbjct: 246 -DEGRMCVNTEWGAFGDSGELDEFLLEYDRLVDESSANPGQQLYEKLIGGKYMGELVRLV 304
Query: 317 LLDLYDSGFIFKDQDISKLKEAYVMDTSYPSKIEDDPFENLEDTDDLFKTNLNIETTVVE 376
LL L D +F + +L+ +T + S++E D + + + L + L + + +
Sbjct: 305 LLRLVDENLLFHGEASEQLRTRGAFETRFVSQVESDTGDRKQIYNIL--STLGLRPSTTD 362
Query: 377 RKLIRKLAELVGTRAARLTVCGVSAICDKRGYKTAH------IAADGSVFNRYPGYKEKA 430
++R+ E V TRAA + G++ + ++ + + DGSV+ +P +KE+
Sbjct: 363 CDIVRRACESVSTRAAHMCSAGLAGVINRMRESRSEDVMRITVGVDGSVYKLHPSFKERF 422
Query: 431 AQALKDIYNWDVEKMEDHPIQLVAAEDGSGVGAAIIACLTQKR 473
+++ + I + +E+GSG GAA+++ + K+
Sbjct: 423 HASVRRL-------TPSCEITFIESEEGSGRGAALVSAVACKK 458
>CE05628 [G] KOG1369 Hexokinase
Length = 500
Score = 265 bits (677), Expect = 1e-70
Identities = 171/459 (37%), Positives = 255/459 (55%), Gaps = 27/459 (5%)
Query: 36 VSSEKMRSIVKHFISELDKGL--SKKGGNIPMIPGWVVEYPTGKETGDFLALDLGGTNLR 93
+S +++R I++ +++GL S K + M+P +V P G E+GDFLALDLGGTN R
Sbjct: 48 LSDQQLRRIMQSMEKSMEQGLATSTKKVAVKMLPTYVDSVPNGTESGDFLALDLGGTNFR 107
Query: 94 VVLVKLGGNHDFDTTQNKYRLPDHLRTGTSEQLWSFIAKCLKEFVDEWYPDGVSEPLPLG 153
V+ +KL G + T +R+P+ + GT E L+ IA C+ +F+ E ++ LPLG
Sbjct: 108 VLHIKLQGK-ETKMTGKIFRVPESIMRGTGEALFDHIAGCMAKFMGENDLKD-AQKLPLG 165
Query: 154 FTFSYPASQKKINSGVLQRWTKGFDIEGVEGHDVVPMLQEQIEKL-NIPINVVALINDTT 212
FTFS+P Q+ + G L WTKGF GVEG DVV +L E + +I I+VVAL+NDT
Sbjct: 166 FTFSFPCEQEGLTKGKLVTWTKGFKASGVEGVDVVTLLHEACHRRKDIDIDVVALLNDTV 225
Query: 213 GTLVASLYTDPQTKMGIIIGTGVNGAYYDVVSGIEKLEGLLPEDIGPDSPMAINCEYGSF 272
GTL+A + + ++G+I+GTG N Y + + I KL G + E M IN E+G+F
Sbjct: 226 GTLMACAFQENSCQIGVIVGTGTNACYMERLDRIPKLAGYVDEHGVTPEEMIINTEWGAF 285
Query: 273 -DNEHLVLPRTKYDVIIDEESPRPGQQAFEKMTSGYYLGEIMRLVLLDLYDSGFIFKDQD 331
D+ L RT++D ++D ES PGQ +EKM SG Y+GE R+VL DL G +F
Sbjct: 286 GDDGALDFLRTEWDEVVDRESINPGQHLYEKMISGMYMGECARVVLEDLAKQGLLFGGNS 345
Query: 332 ISKLKEAYVMDTSYPSKIEDDPFENLEDTDDLF-KTNLNIETTVVER------KLIRKLA 384
+ + T + S+I+ D LED D F KT +E VE + +
Sbjct: 346 -DAISVPHCFPTKFVSEIDSD---LLEDDDRTFQKTYQILEDIGVEMITANDCANVAYVC 401
Query: 385 ELVGTRAARLTVCGVSAICDKRGYKTAHIAADGSVFNRYPGYKEKAAQALKDIYNWDVEK 444
L+ TRAA LT G++ + ++ K + DGSV+ +P Y + ++ D+E
Sbjct: 402 SLISTRAAHLTAAGIAMLLNRMNKKHVTVGVDGSVYRFHPTYPTLLDAKIGELIVGDIE- 460
Query: 445 MEDHPIQLVAAEDGSGVGAAIIAC----LTQKRLAAGKS 479
+L+ +EDGSG GAA++A L +++LAA S
Sbjct: 461 -----YKLMLSEDGSGRGAALVAAVATRLKEEKLAASLS 494
>Hs15553127 [G] KOG1369 Hexokinase
Length = 917
Score = 265 bits (676), Expect = 1e-70
Identities = 160/456 (35%), Positives = 262/456 (57%), Gaps = 31/456 (6%)
Query: 36 VSSEKMRSIVKHFISELDKGLSKK---GGNIPMIPGWVVEYPTGKETGDFLALDLGGTNL 92
+S +++ + + E+++GLSK+ + M+P +V P G E GDFLALDLGGTN
Sbjct: 479 LSHDQLLEVKRRMKVEMERGLSKETHASAPVKMLPTYVCATPDGTEKGDFLALDLGGTNF 538
Query: 93 RVVLVKL-GGNHDFDTTQNK-YRLPDHLRTGTSEQLWSFIAKCLKEFVDEWYPDGVSEPL 150
RV+LV++ G NK Y +P + GT ++L+ I +C+ +F++ GVS L
Sbjct: 539 RVLLVRVRNGKWGGVEMHNKIYAIPQEVMHGTGDELFDHIVQCIADFLEYMGMKGVS--L 596
Query: 151 PLGFTFSYPASQKKINSGVLQRWTKGFDIEGVEGHDVVPMLQEQIEKLN-IPINVVALIN 209
PLGFTFS+P Q ++ +L +WTKGF G EG DVV +L+E I + ++VVA++N
Sbjct: 597 PLGFTFSFPCQQNSLDESILLKWTKGFKASGCEGEDVVTLLKEAIHRREEFDLDVVAVVN 656
Query: 210 DTTGTLVASLYTDPQTKMGIIIGTGVNGAYYDVVSGIEKLEGLLPEDIGPDSPMAINCEY 269
DT GT++ + DP ++G+I+GTG N Y + + +E +EG + M +N E+
Sbjct: 657 DTVGTMMTCGFEDPHCEVGLIVGTGSNACYMEEMRNVELVEG-------EEGRMCVNMEW 709
Query: 270 GSF-DNEHLVLPRTKYDVIIDEESPRPGQQAFEKMTSGYYLGEIMRLVLLDLYDSGFIFK 328
G+F DN L RT++DV +DE S PG+Q FEKM SG YLGEI+R +L+D G +F+
Sbjct: 710 GAFGDNGCLDDFRTEFDVAVDELSLNPGKQRFEKMISGMYLGEIVRNILIDFTKRGLLFR 769
Query: 329 DQDISKLKEAYVMDTSYPSKIEDDPFENLEDTDDLFKTNLNIETTVVERKLIRKLAELVG 388
+ +LK + +T + S+IE D L+ L +L +E+T + +++++ +V
Sbjct: 770 GRISERLKTRGIFETKFLSQIESDCLALLQVRAIL--QHLGLESTCDDSIIVKEVCTVVA 827
Query: 389 TRAARLTVCGVSAICDK----RGYKT--AHIAADGSVFNRYPGYKEKAAQALKDIYNWDV 442
RAA+L G++A+ D+ RG + DG+++ +P + + + +KD+
Sbjct: 828 RRAAQLCGAGMAAVVDRIRENRGLDALKVTVGVDGTLYKLHPHFAKVMHETVKDL----A 883
Query: 443 EKMEDHPIQLVAAEDGSGVGAAIIACLTQKRLAAGK 478
K + + + +EDGSG GAA+I + + AG+
Sbjct: 884 PKCD---VSFLQSEDGSGKGAALITAVACRIREAGQ 916
Score = 228 bits (581), Expect = 2e-59
Identities = 146/450 (32%), Positives = 246/450 (54%), Gaps = 31/450 (6%)
Query: 36 VSSEKMRSIVKHFISELDKGL---SKKGGNIPMIPGWVVEYPTGKETGDFLALDLGGTNL 92
+S E + I K F E++KGL + + M+P +V P G E G+FLALDLGGTN
Sbjct: 31 LSDETLLEISKRFRKEMEKGLGATTHPTAAVKMLPTFVRSTPDGTEHGEFLALDLGGTNF 90
Query: 93 RVVLVKLGGN--HDFDTTQNKYRLPDHLRTGTSEQLWSFIAKCLKEFVDEWYPDGVSEPL 150
RV+ VK+ N + Y +P+ + G+ QL+ IA+CL F+D+ + L
Sbjct: 91 RVLWVKVTDNGLQKVEMENQIYAIPEDIMRGSGTQLFDHIAECLANFMDKLQIK--DKKL 148
Query: 151 PLGFTFSYPASQKKINSGVLQRWTKGFDIEGVEGHDVVPMLQEQIEKL-NIPINVVALIN 209
PLGFTFS+P Q K++ L WTKGF GVEG DVV ++++ I++ + I++VA++N
Sbjct: 149 PLGFTFSFPCHQTKLDESFLVSWTKGFKSSGVEGRDVVALIRKAIQRRGDFDIDIVAVVN 208
Query: 210 DTTGTLVASLYTDPQTKMGIIIGTGVNGAYYDVVSGIEKLEGLLPEDIGPDSPMAINCEY 269
DT GT++ Y D ++G+I+GTG N Y + + I+ +E G + M IN E+
Sbjct: 209 DTVGTMMTCGYDDHNCEIGLIVGTGSNACYMEEMRHIDMVE-------GDEGRMCINMEW 261
Query: 270 GSF-DNEHLVLPRTKYDVIIDEESPRPGQQAFEKMTSGYYLGEIMRLVLLDLYDSGFIFK 328
G+F D+ L RT++D ID S PG+Q FEKM SG Y+GE++RL+L+ + +F
Sbjct: 262 GAFGDDGSLNDIRTEFDQEIDMGSLNPGKQLFEKMISGMYMGELVRLILVKMAKEELLFG 321
Query: 329 DQDISKLKEAYVMDTSYPSKIEDDPFENLEDTDDLFKTNLNIETTVVERKLIRKLAELVG 388
+ +L +T S IE + + + L + L ++ T + ++ ++V
Sbjct: 322 GKLSPELLNTGRFETKDISDIEGEKDGIRKAREVLMR--LGLDPTQEDCVATHRICQIVS 379
Query: 389 TRAARLTVCGVSAIC----DKRGYK--TAHIAADGSVFNRYPGYKEKAAQALKDIYNWDV 442
TR+A L ++A+ + +G + + I DGSV+ ++P + ++ + ++ +
Sbjct: 380 TRSASLCAATLAAVLQRIKENKGEERLRSTIGVDGSVYKKHPHFAKRLHKTVRRL----- 434
Query: 443 EKMEDHPIQLVAAEDGSGVGAAIIACLTQK 472
+ ++ + +EDGSG GAA++ + +
Sbjct: 435 --VPGCDVRFLRSEDGSGKGAAMVTAVAYR 462
>YDR516c [G] KOG1369 Hexokinase
Length = 500
Score = 264 bits (675), Expect = 2e-70
Identities = 177/474 (37%), Positives = 251/474 (52%), Gaps = 45/474 (9%)
Query: 36 VSSEKMRSIVKHFISELDKGLSKKG--------GNIPMIPGWVVEYPTGKETGDFLALDL 87
V + K+ + +FI ++KGL+ +PMIP +V P G E G LA DL
Sbjct: 27 VDAAKLDELTAYFIECMEKGLNNTSVGEEKTVDKGLPMIPTYVTSLPNGTERGVLLAADL 86
Query: 88 GGTNLRVVLVKLGGNHDFDTTQNKYRLPDHL---RTGTSEQLWSFIAKCLKEFVDEWYPD 144
GGT+ RV V L G+ FD Q K ++P+ + TSE+L+S++ + + FV + +P+
Sbjct: 87 GGTHFRVCSVTLNGDGTFDMQQLKSKIPEEYLNDKDVTSEELFSYLGRRTRAFVRKHHPE 146
Query: 145 GVS------EPLPLGFTFSYPASQKKINSGVLQRWTKGFDIEGVEGHDVVPMLQEQIEKL 198
+ +PL +GFTFSYP Q ++SG L RWTK F IE G DVV + QEQ++
Sbjct: 147 LLKSTGENIKPLKMGFTFSYPVDQTSLSSGTLIRWTKSFKIEDTVGKDVVRLYQEQLDIQ 206
Query: 199 NIP-INVVALINDTTGTLVASLYTD----------PQTKMGIIIGTGVNGAYYDVVSGIE 247
+ INVVAL NDT GT ++ YT + +G I GTG NG Y + + I+
Sbjct: 207 GLSMINVVALTNDTVGTFLSHCYTSGSRPSSAGEISEPVIGCIFGTGTNGCYMEDIENIK 266
Query: 248 KLEGLLPEDIGPD--SPMAINCEYGSFDNEHLVLPRTKYDVIIDEE-SPRPGQQAFEKMT 304
KL L + + + M IN E+GSFDNE L TKYD+ ID++ SP PG FEK
Sbjct: 267 KLPDELRTRLLHEGKTQMCINIEWGSFDNELKHLSATKYDIDIDQKFSPNPGYHLFEKRI 326
Query: 305 SGYYLGEIMRLVLLDLYDSGFIF-----KDQDISKLKEAYVMDTSYPSKIEDDPFENLED 359
SG YLGE++R +L+DL+ G I DQ +LK + + + S+IE D NL +
Sbjct: 327 SGMYLGELLRNILVDLHARGLILGQYRNYDQLPHRLKTPFQLCSEVLSRIEIDDSTNLRE 386
Query: 360 TDDLFKTNLNIETTVVERKLIRKLAELVGTRAARLTVCGVSAI------CDKRGYKTAHI 413
T+ F +L + TT ERK I+ L + R+A L ++AI +KR + I
Sbjct: 387 TELSFLQSLRLPTTFEERKAIQNLVRSITRRSAYLAAVPIAAILIKTNALNKRYHGEVEI 446
Query: 414 AADGSVFNRYPGYKEKAAQALKDIYNWDVEKMEDHPIQLVAAEDGSGVGAAIIA 467
DG V YPG++ AL + + I L A+DGSGVGAA+ A
Sbjct: 447 GFDGYVIEYYPGFRSMLRHALA---LSPIGTEGERKIHLRLAKDGSGVGAALCA 497
>7291070 [G] KOG1369 Hexokinase
Length = 541
Score = 263 bits (671), Expect = 6e-70
Identities = 164/458 (35%), Positives = 249/458 (53%), Gaps = 25/458 (5%)
Query: 21 ANLMEQIHGLETLFTVSSEKMRSIVKHFISELDKGLSKKG---GNIPMIPGWVVEYPTGK 77
A + +H L ++ E+++ + + EL +GL+K N+ +V + P G
Sbjct: 89 AEKSKMVHELCQQLLLTDEQVQELCYRILHELRRGLAKDTHPKANVKCFVTYVQDLPNGN 148
Query: 78 ETGDFLALDLGGTNLRVVLVKLGGNHDFDTTQNKYRLPDHLRTGTSEQLWSFIAKCLKEF 137
E G FLALDLGGTN RV+L+ L N+DF Y +P H+ G+ QL+ IA+CL F
Sbjct: 149 ERGKFLALDLGGTNFRVLLIHLQENNDFQMESRIYAIPQHIMIGSGTQLFDHIAECLSNF 208
Query: 138 VDEWYPDGVSEPLPLGFTFSYPASQKKINSGVLQRWTKGFDIEGVEGHDVVPMLQEQIEK 197
+ E + E LPLGFTFS+P Q + G+L+ WTKGF+ GV DVV +L++ I +
Sbjct: 209 MAE--HNVYKERLPLGFTFSFPLRQLGLTKGLLETWTKGFNCAGVVNEDVVQLLKDAIAR 266
Query: 198 L-NIPINVVALINDTTGTLVASLYTDPQTKMGIIIGTGVNGAYYDVVSGIEKLEGLLPED 256
++ I+V A++NDTTGTL++ + + K+G+I+GTG N Y + +E+ E ED
Sbjct: 267 RGDVQIDVCAILNDTTGTLMSCAWKNHNCKIGLIVGTGANACY---MERVEEAELFAAED 323
Query: 257 IGPDSPMAINCEYGSF-DNEHLVLPRTKYDVIIDEESPRPGQQAFEKMTSGYYLGEIMRL 315
+ IN E+G+F DN L RT++D ID S PG+Q FEKM SG Y+GE++RL
Sbjct: 324 -PRKKHVLINTEWGAFGDNGALDFVRTEFDRDIDVHSINPGKQTFEKMISGMYMGELVRL 382
Query: 316 VLLDLYDSGFIFKDQDISKLKEAYVMDTSYPSKIEDDPFENLEDTDDLFKTNLNIETTVV 375
VL+ + +G +F QD L + T Y S+IE D N + + + T
Sbjct: 383 VLVKMTQAGILFNGQDSEVLNTRGLFFTKYVSEIEADEPGNFTNCRLVLEELGLTNATDG 442
Query: 376 ERKLIRKLAELVGTRAARLTVCGVSAICDKRGYKTAHIAADGSVFNRYPGYK----EKAA 431
+ +R + E V RAA L G++ + +K T + DGSV+ +P + EK +
Sbjct: 443 DCANVRYICECVSKRAAHLVSAGIATLINKMDEPTVTVGVDGSVYRFHPKFHNLMVEKIS 502
Query: 432 QALKDIYNWDVEKMEDHPIQLVAAEDGSGVGAAIIACL 469
Q +K +D L+ +EDGSG GAA++A +
Sbjct: 503 QLIKPGITFD----------LMLSEDGSGRGAALVAAV 530
>Hs15991833 [G] KOG1369 Hexokinase
Length = 905
Score = 262 bits (669), Expect = 1e-69
Identities = 162/455 (35%), Positives = 253/455 (55%), Gaps = 35/455 (7%)
Query: 31 ETL--FTVSSEKMRSIVKHFISELDKGLSKKGGN---IPMIPGWVVEYPTGKETGDFLAL 85
ETL F ++ + + + K +E++ GL K+ N + M+P +V P G E GDFLAL
Sbjct: 460 ETLAHFHLTKDMLLEVKKRMRAEMELGLRKQTHNNAVVKMLPSFVRRTPDGTENGDFLAL 519
Query: 86 DLGGTNLRVVLVKL--GGNHDFDTTQNKYRLPDHLRTGTSEQLWSFIAKCLKEFVDEWYP 143
DLGGTN RV+LVK+ G + Y +P + GT E+L+ I C+ +F+D
Sbjct: 520 DLGGTNFRVLLVKIRSGKKRTVEMHNKIYAIPIEIMQGTGEELFDHIVSCISDFLDYM-- 577
Query: 144 DGVSEP-LPLGFTFSYPASQKKINSGVLQRWTKGFDIEGVEGHDVVPMLQEQIEKLN-IP 201
G+ P +PLGFTFS+P Q +++G+L WTKGF GHDVV +L++ I++
Sbjct: 578 -GIKGPRMPLGFTFSFPCQQTSLDAGILITWTKGFKATDCVGHDVVTLLRDAIKRREEFD 636
Query: 202 INVVALINDTTGTLVASLYTDPQTKMGIIIGTGVNGAYYDVVSGIEKLEGLLPEDIGPDS 261
++VVA++NDT GT++ Y +P ++G+I+GTG N Y + + +E +EG
Sbjct: 637 LDVVAVVNDTVGTMMTCAYEEPTCEVGLIVGTGSNACYMEEMKNVEMVEG-------DQG 689
Query: 262 PMAINCEYGSF-DNEHLVLPRTKYDVIIDEESPRPGQQAFEKMTSGYYLGEIMRLVLLDL 320
M IN E+G+F DN L RT YD ++DE S G+Q +EKM SG YLGEI+R +L+D
Sbjct: 690 QMCINMEWGAFGDNGCLDDIRTHYDRLVDEYSLNAGKQRYEKMISGMYLGEIVRNILIDF 749
Query: 321 YDSGFIFKDQDISKLKEAYVMDTSYPSKIEDDPFENLEDTDDLFKTNLNIETTVVERKLI 380
GF+F+ Q LK + +T + S+IE D L+ L + LN +T + L+
Sbjct: 750 TKKGFLFRGQISETLKTRGIFETKFLSQIESDRLALLQVRAILQQLGLN--STCDDSILV 807
Query: 381 RKLAELVGTRAARLTVCGVSAICDK----RGYKTAH--IAADGSVFNRYPGYKEKAAQAL 434
+ + +V RAA+L G++A+ DK RG + + DG+++ +P + Q +
Sbjct: 808 KTVCGVVSRRAAQLCGAGMAAVVDKIRENRGLDRLNVTVGVDGTLYKLHPHFSRIMHQTV 867
Query: 435 KDIYNWDVEKMEDHPIQLVAAEDGSGVGAAIIACL 469
K++ + + +EDGSG GAA+I +
Sbjct: 868 KEL-------SPKCNVSFLLSEDGSGKGAALITAV 895
Score = 230 bits (587), Expect = 3e-60
Identities = 147/450 (32%), Positives = 243/450 (53%), Gaps = 31/450 (6%)
Query: 36 VSSEKMRSIVKHFISELDKGLSKK---GGNIPMIPGWVVEYPTGKETGDFLALDLGGTNL 92
+S E + I+ F E+ GLS+ + M+P +V P G E GDF+ALDLGG++
Sbjct: 19 LSDETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSEKGDFIALDLGGSSF 78
Query: 93 RVVLVKLGG--NHDFDTTQNKYRLPDHLRTGTSEQLWSFIAKCLKEFVDEWYPDGVSEPL 150
R++ V++ N + Y P+++ G+ QL+ +A+CL +F+++ + L
Sbjct: 79 RILRVQVNHEKNQNVHMESEVYDTPENIVHGSGSQLFDHVAECLGDFMEKRKIK--DKKL 136
Query: 151 PLGFTFSYPASQKKINSGVLQRWTKGFDIEGVEGHDVVPMLQEQIEKL-NIPINVVALIN 209
P+GFTFS+P Q KI+ +L WTK F GVEG DVV +L + I+K + N+VA++N
Sbjct: 137 PVGFTFSFPCQQSKIDEAILITWTKRFKASGVEGADVVKLLNKAIKKRGDYDANIVAVVN 196
Query: 210 DTTGTLVASLYTDPQTKMGIIIGTGVNGAYYDVVSGIEKLEGLLPEDIGPDSPMAINCEY 269
DT GT++ Y D ++G+IIGTG N Y + + I+ +E G + M IN E+
Sbjct: 197 DTVGTMMTCGYDDQHCEVGLIIGTGTNACYMEELRHIDLVE-------GDEGRMCINTEW 249
Query: 270 GSF-DNEHLVLPRTKYDVIIDEESPRPGQQAFEKMTSGYYLGEIMRLVLLDLYDSGFIFK 328
G+F D+ L RT++D ID S PG+Q FEKM SG YLGE++RL+L+ + G +F+
Sbjct: 250 GAFGDDGSLEDIRTEFDREIDRGSLNPGKQLFEKMVSGMYLGELVRLILVKMAKEGLLFE 309
Query: 329 DQDISKLKEAYVMDTSYPSKIEDDPFENLEDTDDLFKTNLNIETTVVERKLIRKLAELVG 388
+ +L +TS S IE + E L + ++ T L +E + + ++ + +V
Sbjct: 310 GRITPELLTRGKFNTSDVSAIEKNK-EGLHNAKEIL-TRLGVEPSDDDCVSVQHVCTIVS 367
Query: 389 TRAARLTVCGVSAIC----DKRGYKTAH--IAADGSVFNRYPGYKEKAAQALKDIYNWDV 442
R+A L + AI D +G + DGS++ +P Y + + L+ +
Sbjct: 368 FRSANLVAATLGAILNRLRDNKGTPRLRTTVGVDGSLYKTHPQYSRRFHKTLRRL----- 422
Query: 443 EKMEDHPIQLVAAEDGSGVGAAIIACLTQK 472
+ D ++ + +E GSG GAA++ + +
Sbjct: 423 --VPDSDVRFLLSESGSGKGAAMVTAVAYR 450
>Hs15991829 [G] KOG1369 Hexokinase
Length = 921
Score = 262 bits (669), Expect = 1e-69
Identities = 162/455 (35%), Positives = 253/455 (55%), Gaps = 35/455 (7%)
Query: 31 ETL--FTVSSEKMRSIVKHFISELDKGLSKKGGN---IPMIPGWVVEYPTGKETGDFLAL 85
ETL F ++ + + + K +E++ GL K+ N + M+P +V P G E GDFLAL
Sbjct: 476 ETLAHFHLTKDMLLEVKKRMRAEMELGLRKQTHNNAVVKMLPSFVRRTPDGTENGDFLAL 535
Query: 86 DLGGTNLRVVLVKL--GGNHDFDTTQNKYRLPDHLRTGTSEQLWSFIAKCLKEFVDEWYP 143
DLGGTN RV+LVK+ G + Y +P + GT E+L+ I C+ +F+D
Sbjct: 536 DLGGTNFRVLLVKIRSGKKRTVEMHNKIYAIPIEIMQGTGEELFDHIVSCISDFLDYM-- 593
Query: 144 DGVSEP-LPLGFTFSYPASQKKINSGVLQRWTKGFDIEGVEGHDVVPMLQEQIEKLN-IP 201
G+ P +PLGFTFS+P Q +++G+L WTKGF GHDVV +L++ I++
Sbjct: 594 -GIKGPRMPLGFTFSFPCQQTSLDAGILITWTKGFKATDCVGHDVVTLLRDAIKRREEFD 652
Query: 202 INVVALINDTTGTLVASLYTDPQTKMGIIIGTGVNGAYYDVVSGIEKLEGLLPEDIGPDS 261
++VVA++NDT GT++ Y +P ++G+I+GTG N Y + + +E +EG
Sbjct: 653 LDVVAVVNDTVGTMMTCAYEEPTCEVGLIVGTGSNACYMEEMKNVEMVEG-------DQG 705
Query: 262 PMAINCEYGSF-DNEHLVLPRTKYDVIIDEESPRPGQQAFEKMTSGYYLGEIMRLVLLDL 320
M IN E+G+F DN L RT YD ++DE S G+Q +EKM SG YLGEI+R +L+D
Sbjct: 706 QMCINMEWGAFGDNGCLDDIRTHYDRLVDEYSLNAGKQRYEKMISGMYLGEIVRNILIDF 765
Query: 321 YDSGFIFKDQDISKLKEAYVMDTSYPSKIEDDPFENLEDTDDLFKTNLNIETTVVERKLI 380
GF+F+ Q LK + +T + S+IE D L+ L + LN +T + L+
Sbjct: 766 TKKGFLFRGQISETLKTRGIFETKFLSQIESDRLALLQVRAILQQLGLN--STCDDSILV 823
Query: 381 RKLAELVGTRAARLTVCGVSAICDK----RGYKTAH--IAADGSVFNRYPGYKEKAAQAL 434
+ + +V RAA+L G++A+ DK RG + + DG+++ +P + Q +
Sbjct: 824 KTVCGVVSRRAAQLCGAGMAAVVDKIRENRGLDRLNVTVGVDGTLYKLHPHFSRIMHQTV 883
Query: 435 KDIYNWDVEKMEDHPIQLVAAEDGSGVGAAIIACL 469
K++ + + +EDGSG GAA+I +
Sbjct: 884 KEL-------SPKCNVSFLLSEDGSGKGAALITAV 911
Score = 230 bits (587), Expect = 3e-60
Identities = 147/450 (32%), Positives = 243/450 (53%), Gaps = 31/450 (6%)
Query: 36 VSSEKMRSIVKHFISELDKGLSKK---GGNIPMIPGWVVEYPTGKETGDFLALDLGGTNL 92
+S E + I+ F E+ GLS+ + M+P +V P G E GDF+ALDLGG++
Sbjct: 35 LSDETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSEKGDFIALDLGGSSF 94
Query: 93 RVVLVKLGG--NHDFDTTQNKYRLPDHLRTGTSEQLWSFIAKCLKEFVDEWYPDGVSEPL 150
R++ V++ N + Y P+++ G+ QL+ +A+CL +F+++ + L
Sbjct: 95 RILRVQVNHEKNQNVHMESEVYDTPENIVHGSGSQLFDHVAECLGDFMEKRKIK--DKKL 152
Query: 151 PLGFTFSYPASQKKINSGVLQRWTKGFDIEGVEGHDVVPMLQEQIEKL-NIPINVVALIN 209
P+GFTFS+P Q KI+ +L WTK F GVEG DVV +L + I+K + N+VA++N
Sbjct: 153 PVGFTFSFPCQQSKIDEAILITWTKRFKASGVEGADVVKLLNKAIKKRGDYDANIVAVVN 212
Query: 210 DTTGTLVASLYTDPQTKMGIIIGTGVNGAYYDVVSGIEKLEGLLPEDIGPDSPMAINCEY 269
DT GT++ Y D ++G+IIGTG N Y + + I+ +E G + M IN E+
Sbjct: 213 DTVGTMMTCGYDDQHCEVGLIIGTGTNACYMEELRHIDLVE-------GDEGRMCINTEW 265
Query: 270 GSF-DNEHLVLPRTKYDVIIDEESPRPGQQAFEKMTSGYYLGEIMRLVLLDLYDSGFIFK 328
G+F D+ L RT++D ID S PG+Q FEKM SG YLGE++RL+L+ + G +F+
Sbjct: 266 GAFGDDGSLEDIRTEFDREIDRGSLNPGKQLFEKMVSGMYLGELVRLILVKMAKEGLLFE 325
Query: 329 DQDISKLKEAYVMDTSYPSKIEDDPFENLEDTDDLFKTNLNIETTVVERKLIRKLAELVG 388
+ +L +TS S IE + E L + ++ T L +E + + ++ + +V
Sbjct: 326 GRITPELLTRGKFNTSDVSAIEKNK-EGLHNAKEIL-TRLGVEPSDDDCVSVQHVCTIVS 383
Query: 389 TRAARLTVCGVSAIC----DKRGYKTAH--IAADGSVFNRYPGYKEKAAQALKDIYNWDV 442
R+A L + AI D +G + DGS++ +P Y + + L+ +
Sbjct: 384 FRSANLVAATLGAILNRLRDNKGTPRLRTTVGVDGSLYKTHPQYSRRFHKTLRRL----- 438
Query: 443 EKMEDHPIQLVAAEDGSGVGAAIIACLTQK 472
+ D ++ + +E GSG GAA++ + +
Sbjct: 439 --VPDSDVRFLLSESGSGKGAAMVTAVAYR 466
>Hs15991827 [G] KOG1369 Hexokinase
Length = 916
Score = 262 bits (669), Expect = 1e-69
Identities = 162/455 (35%), Positives = 253/455 (55%), Gaps = 35/455 (7%)
Query: 31 ETL--FTVSSEKMRSIVKHFISELDKGLSKKGGN---IPMIPGWVVEYPTGKETGDFLAL 85
ETL F ++ + + + K +E++ GL K+ N + M+P +V P G E GDFLAL
Sbjct: 471 ETLAHFHLTKDMLLEVKKRMRAEMELGLRKQTHNNAVVKMLPSFVRRTPDGTENGDFLAL 530
Query: 86 DLGGTNLRVVLVKL--GGNHDFDTTQNKYRLPDHLRTGTSEQLWSFIAKCLKEFVDEWYP 143
DLGGTN RV+LVK+ G + Y +P + GT E+L+ I C+ +F+D
Sbjct: 531 DLGGTNFRVLLVKIRSGKKRTVEMHNKIYAIPIEIMQGTGEELFDHIVSCISDFLDYM-- 588
Query: 144 DGVSEP-LPLGFTFSYPASQKKINSGVLQRWTKGFDIEGVEGHDVVPMLQEQIEKLN-IP 201
G+ P +PLGFTFS+P Q +++G+L WTKGF GHDVV +L++ I++
Sbjct: 589 -GIKGPRMPLGFTFSFPCQQTSLDAGILITWTKGFKATDCVGHDVVTLLRDAIKRREEFD 647
Query: 202 INVVALINDTTGTLVASLYTDPQTKMGIIIGTGVNGAYYDVVSGIEKLEGLLPEDIGPDS 261
++VVA++NDT GT++ Y +P ++G+I+GTG N Y + + +E +EG
Sbjct: 648 LDVVAVVNDTVGTMMTCAYEEPTCEVGLIVGTGSNACYMEEMKNVEMVEG-------DQG 700
Query: 262 PMAINCEYGSF-DNEHLVLPRTKYDVIIDEESPRPGQQAFEKMTSGYYLGEIMRLVLLDL 320
M IN E+G+F DN L RT YD ++DE S G+Q +EKM SG YLGEI+R +L+D
Sbjct: 701 QMCINMEWGAFGDNGCLDDIRTHYDRLVDEYSLNAGKQRYEKMISGMYLGEIVRNILIDF 760
Query: 321 YDSGFIFKDQDISKLKEAYVMDTSYPSKIEDDPFENLEDTDDLFKTNLNIETTVVERKLI 380
GF+F+ Q LK + +T + S+IE D L+ L + LN +T + L+
Sbjct: 761 TKKGFLFRGQISETLKTRGIFETKFLSQIESDRLALLQVRAILQQLGLN--STCDDSILV 818
Query: 381 RKLAELVGTRAARLTVCGVSAICDK----RGYKTAH--IAADGSVFNRYPGYKEKAAQAL 434
+ + +V RAA+L G++A+ DK RG + + DG+++ +P + Q +
Sbjct: 819 KTVCGVVSRRAAQLCGAGMAAVVDKIRENRGLDRLNVTVGVDGTLYKLHPHFSRIMHQTV 878
Query: 435 KDIYNWDVEKMEDHPIQLVAAEDGSGVGAAIIACL 469
K++ + + +EDGSG GAA+I +
Sbjct: 879 KEL-------SPKCNVSFLLSEDGSGKGAALITAV 906
Score = 230 bits (587), Expect = 3e-60
Identities = 147/450 (32%), Positives = 243/450 (53%), Gaps = 31/450 (6%)
Query: 36 VSSEKMRSIVKHFISELDKGLSKK---GGNIPMIPGWVVEYPTGKETGDFLALDLGGTNL 92
+S E + I+ F E+ GLS+ + M+P +V P G E GDF+ALDLGG++
Sbjct: 30 LSDETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSEKGDFIALDLGGSSF 89
Query: 93 RVVLVKLGG--NHDFDTTQNKYRLPDHLRTGTSEQLWSFIAKCLKEFVDEWYPDGVSEPL 150
R++ V++ N + Y P+++ G+ QL+ +A+CL +F+++ + L
Sbjct: 90 RILRVQVNHEKNQNVHMESEVYDTPENIVHGSGSQLFDHVAECLGDFMEKRKIK--DKKL 147
Query: 151 PLGFTFSYPASQKKINSGVLQRWTKGFDIEGVEGHDVVPMLQEQIEKL-NIPINVVALIN 209
P+GFTFS+P Q KI+ +L WTK F GVEG DVV +L + I+K + N+VA++N
Sbjct: 148 PVGFTFSFPCQQSKIDEAILITWTKRFKASGVEGADVVKLLNKAIKKRGDYDANIVAVVN 207
Query: 210 DTTGTLVASLYTDPQTKMGIIIGTGVNGAYYDVVSGIEKLEGLLPEDIGPDSPMAINCEY 269
DT GT++ Y D ++G+IIGTG N Y + + I+ +E G + M IN E+
Sbjct: 208 DTVGTMMTCGYDDQHCEVGLIIGTGTNACYMEELRHIDLVE-------GDEGRMCINTEW 260
Query: 270 GSF-DNEHLVLPRTKYDVIIDEESPRPGQQAFEKMTSGYYLGEIMRLVLLDLYDSGFIFK 328
G+F D+ L RT++D ID S PG+Q FEKM SG YLGE++RL+L+ + G +F+
Sbjct: 261 GAFGDDGSLEDIRTEFDREIDRGSLNPGKQLFEKMVSGMYLGELVRLILVKMAKEGLLFE 320
Query: 329 DQDISKLKEAYVMDTSYPSKIEDDPFENLEDTDDLFKTNLNIETTVVERKLIRKLAELVG 388
+ +L +TS S IE + E L + ++ T L +E + + ++ + +V
Sbjct: 321 GRITPELLTRGKFNTSDVSAIEKNK-EGLHNAKEIL-TRLGVEPSDDDCVSVQHVCTIVS 378
Query: 389 TRAARLTVCGVSAIC----DKRGYKTAH--IAADGSVFNRYPGYKEKAAQALKDIYNWDV 442
R+A L + AI D +G + DGS++ +P Y + + L+ +
Sbjct: 379 FRSANLVAATLGAILNRLRDNKGTPRLRTTVGVDGSLYKTHPQYSRRFHKTLRRL----- 433
Query: 443 EKMEDHPIQLVAAEDGSGVGAAIIACLTQK 472
+ D ++ + +E GSG GAA++ + +
Sbjct: 434 --VPDSDVRFLLSESGSGKGAAMVTAVAYR 461
>Hs4504391 [G] KOG1369 Hexokinase
Length = 917
Score = 259 bits (662), Expect = 6e-69
Identities = 160/455 (35%), Positives = 253/455 (55%), Gaps = 35/455 (7%)
Query: 31 ETL--FTVSSEKMRSIVKHFISELDKGLSKKGGN---IPMIPGWVVEYPTGKETGDFLAL 85
ETL F ++ + + + K +E++ GL K+ N + M+P +V P G E GDFLAL
Sbjct: 472 ETLAHFHLTKDMLLEVKKRMRAEMELGLRKQTHNNAVVKMLPSFVRRTPDGTENGDFLAL 531
Query: 86 DLGGTNLRVVLVKL--GGNHDFDTTQNKYRLPDHLRTGTSEQLWSFIAKCLKEFVDEWYP 143
DLGGTN RV+LVK+ G + Y +P + GT E+L+ I C+ +F+D
Sbjct: 532 DLGGTNFRVLLVKIRSGKKRTVEMHNKIYAIPIEIMQGTGEELFDHIVSCISDFLDYM-- 589
Query: 144 DGVSEP-LPLGFTFSYPASQKKINSGVLQRWTKGFDIEGVEGHDVVPMLQEQIEKLN-IP 201
G+ P +PLGFTFS+P Q +++G+L WTKGF GHDVV +L++ I++
Sbjct: 590 -GIKGPRMPLGFTFSFPCQQTSLDAGILITWTKGFKATDCVGHDVVTLLRDAIKRREEFD 648
Query: 202 INVVALINDTTGTLVASLYTDPQTKMGIIIGTGVNGAYYDVVSGIEKLEGLLPEDIGPDS 261
++VVA++NDT GT++ Y +P ++G+I+GTG N Y + + +E +EG
Sbjct: 649 LDVVAVVNDTVGTMMTCAYEEPTCEVGLIVGTGSNACYMEEMKNVEMVEG-------DQG 701
Query: 262 PMAINCEYGSF-DNEHLVLPRTKYDVIIDEESPRPGQQAFEKMTSGYYLGEIMRLVLLDL 320
M IN E+G+F DN L RT YD +++E S G+Q +EKM SG YLGEI+R +L+D
Sbjct: 702 QMCINMEWGAFGDNGCLDDIRTHYDRLVNEYSLNAGKQRYEKMISGMYLGEIVRNILIDF 761
Query: 321 YDSGFIFKDQDISKLKEAYVMDTSYPSKIEDDPFENLEDTDDLFKTNLNIETTVVERKLI 380
GF+F+ Q +K + +T + S+IE D L+ L + LN +T + L+
Sbjct: 762 TKKGFLFRGQISETMKTRGIFETKFLSQIESDRLALLQVRAILQQLGLN--STCDDSILV 819
Query: 381 RKLAELVGTRAARLTVCGVSAICDK----RGYKTAH--IAADGSVFNRYPGYKEKAAQAL 434
+ + +V RAA+L G++A+ DK RG + + DG+++ +P + Q +
Sbjct: 820 KTVCGVVSRRAAQLCGAGMAAVVDKIRENRGLDRLNVTVGVDGTLYKLHPHFSRIMHQTV 879
Query: 435 KDIYNWDVEKMEDHPIQLVAAEDGSGVGAAIIACL 469
K++ + + +EDGSG GAA+I +
Sbjct: 880 KEL-------SPKCNVSFLLSEDGSGKGAALITAV 907
Score = 230 bits (587), Expect = 3e-60
Identities = 147/450 (32%), Positives = 243/450 (53%), Gaps = 31/450 (6%)
Query: 36 VSSEKMRSIVKHFISELDKGLSKK---GGNIPMIPGWVVEYPTGKETGDFLALDLGGTNL 92
+S E + I+ F E+ GLS+ + M+P +V P G E GDF+ALDLGG++
Sbjct: 31 LSDETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSEKGDFIALDLGGSSF 90
Query: 93 RVVLVKLGG--NHDFDTTQNKYRLPDHLRTGTSEQLWSFIAKCLKEFVDEWYPDGVSEPL 150
R++ V++ N + Y P+++ G+ QL+ +A+CL +F+++ + L
Sbjct: 91 RILRVQVNHEKNQNVHMESEVYDTPENIVHGSGSQLFDHVAECLGDFMEKRKIK--DKKL 148
Query: 151 PLGFTFSYPASQKKINSGVLQRWTKGFDIEGVEGHDVVPMLQEQIEKL-NIPINVVALIN 209
P+GFTFS+P Q KI+ +L WTK F GVEG DVV +L + I+K + N+VA++N
Sbjct: 149 PVGFTFSFPCQQSKIDEAILITWTKRFKASGVEGADVVKLLNKAIKKRGDYDANIVAVVN 208
Query: 210 DTTGTLVASLYTDPQTKMGIIIGTGVNGAYYDVVSGIEKLEGLLPEDIGPDSPMAINCEY 269
DT GT++ Y D ++G+IIGTG N Y + + I+ +E G + M IN E+
Sbjct: 209 DTVGTMMTCGYDDQHCEVGLIIGTGTNACYMEELRHIDLVE-------GDEGRMCINTEW 261
Query: 270 GSF-DNEHLVLPRTKYDVIIDEESPRPGQQAFEKMTSGYYLGEIMRLVLLDLYDSGFIFK 328
G+F D+ L RT++D ID S PG+Q FEKM SG YLGE++RL+L+ + G +F+
Sbjct: 262 GAFGDDGSLEDIRTEFDREIDRGSLNPGKQLFEKMVSGMYLGELVRLILVKMAKEGLLFE 321
Query: 329 DQDISKLKEAYVMDTSYPSKIEDDPFENLEDTDDLFKTNLNIETTVVERKLIRKLAELVG 388
+ +L +TS S IE + E L + ++ T L +E + + ++ + +V
Sbjct: 322 GRITPELLTRGKFNTSDVSAIEKNK-EGLHNAKEIL-TRLGVEPSDDDCVSVQHVCTIVS 379
Query: 389 TRAARLTVCGVSAIC----DKRGYKTAH--IAADGSVFNRYPGYKEKAAQALKDIYNWDV 442
R+A L + AI D +G + DGS++ +P Y + + L+ +
Sbjct: 380 FRSANLVAATLGAILNRLRDNKGTPRLRTTVGVDGSLYKTHPQYSRRFHKTLRRL----- 434
Query: 443 EKMEDHPIQLVAAEDGSGVGAAIIACLTQK 472
+ D ++ + +E GSG GAA++ + +
Sbjct: 435 --VPDSDVRFLLSESGSGKGAAMVTAVAYR 462
>Hs4504395 [G] KOG1369 Hexokinase
Length = 923
Score = 251 bits (641), Expect = 2e-66
Identities = 152/449 (33%), Positives = 249/449 (54%), Gaps = 30/449 (6%)
Query: 31 ETL--FTVSSEKMRSIVKHFISELDKGLSKKGGNIPMIPGWVVEYPTGKETGDFLALDLG 88
ETL F ++ +++ ++ + KGL + ++ M+P +V P G E GDFLALDLG
Sbjct: 485 ETLAPFRLNHDQLAAVQAQMRKAMAKGLRGEASSLRMLPTFVRATPDGSERGDFLALDLG 544
Query: 89 GTNLRVVLVKLGGNHDFDTTQNKYRLPDHLRTGTSEQLWSFIAKCLKEFVDEWYPDGVSE 148
GTN RV+LV++ T Y +P+ + G+ +QL+ I C+ +F + G S
Sbjct: 545 GTNFRVLLVRV--TTGVQITSEIYSIPETVAQGSGQQLFDHIVDCIVDFQQKQGLSGQS- 601
Query: 149 PLPLGFTFSYPASQKKINSGVLQRWTKGFDIEGVEGHDVVPMLQEQIEKLN-IPINVVAL 207
LPLGFTFS+P Q ++ G+L WTKGF EG DVV +L+E I + + +NVVA+
Sbjct: 602 -LPLGFTFSFPCRQLGLDQGILLNWTKGFKASDCEGQDVVSLLREAITRRQAVELNVVAI 660
Query: 208 INDTTGTLVASLYTDPQTKMGIIIGTGVNGAYYDVVSGIEKLEGLLPEDIGPDSPMAINC 267
+NDT GT+++ Y DP+ ++G+I+GTG N Y + + + + G M IN
Sbjct: 661 VNDTVGTMMSCGYEDPRCEIGLIVGTGTNACYMEELRNVAGVPG-------DSGRMCINM 713
Query: 268 EYGSF-DNEHLVLPRTKYDVIIDEESPRPGQQAFEKMTSGYYLGEIMRLVLLDLYDSGFI 326
E+G+F D+ L + T++D +D+ S PG+Q FEKM SG YLGEI+R +LL L G +
Sbjct: 714 EWGAFGDDGSLAMLSTRFDASVDQASINPGKQRFEKMISGMYLGEIVRHILLHLTSLGVL 773
Query: 327 FKDQDISKLKEAYVMDTSYPSKIEDDPFENLEDTDDLFKTNLNIETTVVERKLIRKLAEL 386
F+ Q I +L+ + T + S+IE D L + + +L + T + ++ ++ +
Sbjct: 774 FRGQQIQRLQTRDIFKTKFLSEIESDSLA-LRQVRAILE-DLGLPLTSDDALMVLEVCQA 831
Query: 387 VGTRAARLTVCGVSAICDK-RGYK-----TAHIAADGSVFNRYPGYKEKAAQALKDIYNW 440
V RAA+L GV+A+ +K RG + + DG+++ +P + A ++++
Sbjct: 832 VSQRAAQLCGAGVAAVVEKIRGNRGLEELAVSVGVDGTLYKLHPRFSSLVAATVRELAPR 891
Query: 441 DVEKMEDHPIQLVAAEDGSGVGAAIIACL 469
V + + +EDGSG GAA++ +
Sbjct: 892 CV-------VTFLQSEDGSGKGAALVTAV 913
Score = 177 bits (449), Expect = 3e-44
Identities = 137/472 (29%), Positives = 229/472 (48%), Gaps = 34/472 (7%)
Query: 20 PANLMEQIHGLETLFTVSSEKMRSIVKHFISELDKGLSKKGGNIP---MIPGWVVEYPTG 76
P++ E + F V+ +++ I + +++ L + P M+P +V P G
Sbjct: 26 PSDSSELVQECLQQFKVTRAQLQQIQASLLGSMEQALRGQASPAPAVRMLPTYVGSTPHG 85
Query: 77 KETGDFLALDLG--GTNLRVVLVKLGG--NHDFDTTQNKYRLPDHLRTGTSEQLWSFIAK 132
E GDF+ L+LG G +LRV+ V L G H + ++ +P + G +QL+ F A
Sbjct: 86 TEQGDFVVLELGATGASLRVLWVTLTGIEGHRVEPRSQEFVIPQEVMLGAGQQLFDFAAH 145
Query: 133 CLKEFVDEWYPDGVSEPLPLGFTFSYPASQKKINSGVLQRWTKGFDIEGVEGHDVVPMLQ 192
CL EF+D + + L LGF+FS+P Q ++ L WTKGF GVEG DVV +L+
Sbjct: 146 CLSEFLDAQPVN--KQGLQLGFSFSFPCHQTGLDRSTLISWTKGFRCSGVEGQDVVQLLR 203
Query: 193 EQIEKLN-IPINVVALINDTTGTLVASLYTDPQTKMGIIIGTGVNGAYYDVVSGIEKLEG 251
+ I + I+VVA++NDT GT++ ++G+++ TG N Y + +
Sbjct: 204 DAIRRQGAYNIDVVAVVNDTVGTMMGCEPGVRPCEVGLVVDTGTNACYMEEARHV----A 259
Query: 252 LLPEDIGPDSPMAINCEYGSFDNEHLVLP-RTKYDVIIDEESPRPGQQAFEKMTSGYYLG 310
+L ED G + ++ E+GS ++ + P T +D +D ES PG Q FEKM G YLG
Sbjct: 260 VLDEDRG---RVCVSVEWGSLSDDGALGPVLTTFDHTLDHESLNPGAQRFEKMIGGLYLG 316
Query: 311 EIMRLVLLDLYDSGFIFKDQDISKLKEAYVMDTSYPSKIEDDPFENLEDTDDLFKTNLNI 370
E++RLVL L G +F L + + +++E DP + + +L +
Sbjct: 317 ELVRLVLAHLARCGVLFGGCTSPALLSQGSILLEHVAEME-DPSTGAARVHAILQ-DLGL 374
Query: 371 ETTVVERKLIRKLAELVGTRAARLTVCGVSAICD----KRGYKTAH--IAADGSVFNRYP 424
+ +L++ + V TRAA+L ++A+ R +T +A G V R+P
Sbjct: 375 SPGASDVELVQHVCAAVCTRAAQLCAAALAAVLSCLQHSREQQTLQVAVATGGRVCERHP 434
Query: 425 GYKEKAAQALKDIYNWDVEKMEDHPIQLVAAEDGSGVGAAIIACLTQKRLAA 476
+ + + + + L+ + DG G G A++ + RLAA
Sbjct: 435 RFCSVLQGTVMLL-------APECDVSLIPSVDGGGRGVAMVTAVA-ARLAA 478
>SPAC4F8.07c [G] KOG1369 Hexokinase
Length = 455
Score = 243 bits (621), Expect = 4e-64
Identities = 161/457 (35%), Positives = 240/457 (52%), Gaps = 25/457 (5%)
Query: 21 ANLMEQIHGLETLFTVSSEKMRSIVKHFISELDKGLSKKGGNIPMIPGWVVEYPTGKETG 80
AN + + L F +E +R VK F KGL K G + M P ++ PTG ETG
Sbjct: 3 ANFQQAVKKLVNDFEYPTESLREAVKEFDELRQKGLQKNGEVLAMAPAFISTLPTGAETG 62
Query: 81 DFLALDLGGTNLRVVLVKLGGNHDFDTTQNKYRLP-DHLRTGTSEQLWSFIAKCLKEFVD 139
DFLALD GGTNLRV ++L G+ ++ +K LP + +R + + + F++ ++ F+
Sbjct: 63 DFLALDFGGTNLRVCWIQLLGDGKYEMKHSKSVLPRECVRNESVKPIIDFMSDHVELFIK 122
Query: 140 EWYPDGVSEP----LPLGFTFSYPASQKKINSGVLQRWTKGFDIEGVEGHDVVPMLQEQI 195
E +P P LP+GFTFSYPA+Q I L RWTKG +I D L E
Sbjct: 123 EHFPSKFGCPEEEYLPMGFTFSYPANQVSITESYLLRWTKGLNIPEAINKDFAQFLTEGF 182
Query: 196 EKLNIPINVVALINDTTGTLVASLYT--DPQTKMGIIIGTGVNGAYYDVVSGIEKLEGLL 253
+ N+PI + A+INDT GTLV YT + T MGII GTG NGAY + ++ I KL G
Sbjct: 183 KARNLPIRIEAVINDTVGTLVTRAYTSKESDTFMGIIFGTGTNGAYVEQMNQIPKLAGKC 242
Query: 254 PEDIGPDSPMAINCEYGSFDNEHLVLPRTKYDVIIDEESPRPGQQAFEKMTSGYYLGEIM 313
D M IN E+G+ D L T+YD+++D ++P G+Q FEK G YLGE+
Sbjct: 243 TGD-----HMLINMEWGATD--FSCLHSTRYDLLLDHDTPNAGRQIFEKRVGGMYLGELF 295
Query: 314 RLVLLDLYDSGFIFKDQDISKLKEAYVMDTSYPSK-IEDDPFENLEDTDDLFKTNLNIET 372
R L L + + +A+ ++TS S+ + + EN+ + FK +
Sbjct: 296 RRALFHLIKVYNFNEGIFPPSITDAWSLETSVLSRMMVERSAENVRNVLSTFKFRFRSDE 355
Query: 373 TVVERKLIRKLAELVGTRAARLTVCGVSA--ICDKRGYKTAHIAADGSVFNRYPGYKEKA 430
E + A +G RAAR++ +++ + R K + + DGS+ YP + +
Sbjct: 356 ---EALYLWDAAHAIGRRAARMSAVPIASLYLSTGRAGKKSDVGVDGSLVEHYPHFVDML 412
Query: 431 AQALKDIYNWDVEKMEDHPIQLVAAEDGSGVGAAIIA 467
+AL+++ D EK+ I + A+DGSG+GAA+ A
Sbjct: 413 REALRELIG-DNEKL----ISIGIAKDGSGIGAALCA 444
>At1g50460 [G] KOG1369 Hexokinase
Length = 498
Score = 241 bits (614), Expect = 2e-63
Identities = 150/455 (32%), Positives = 237/455 (51%), Gaps = 34/455 (7%)
Query: 40 KMRSIVKHFISELDKGLSKKGGN-IPMIPGWVVEYPTGKETGDFLALDLGGTNLRVVLVK 98
++R +V E+ GL+ +GG+ + M+ +V + PTG+E G + AL LGGT R++ V
Sbjct: 54 RLRQVVDAMAVEMHAGLASEGGSKLKMLLTFVDDLPTGREKGTYYALHLGGTYFRILRVL 113
Query: 99 LGGNHDFDTTQN--KYRLPDHLRTGTSEQLWSFIAKCLKEFVDEWYPDGVSEPL--PLGF 154
LG + Q+ ++ +P HL TSE L++F+A L+ F+++ S+ + L F
Sbjct: 114 LGDQRSYLDVQDVERHPIPSHLMNSTSEVLFNFLAFSLERFIEKEENGSDSQGVRRELAF 173
Query: 155 TFSYPASQKKINSGVLQRWTKGFDIEGVEGHDVVPMLQEQIEKLNIPINVVALINDTTGT 214
TFS+P I+SGVL +WTKGF+I + G D+ LQ + + + ++V AL+NDT G
Sbjct: 174 TFSFPVKHTSISSGVLIKWTKGFEISEMVGQDIAECLQGALNRRGLDMHVAALVNDTVGA 233
Query: 215 LVASLYTDPQTKMGIIIGTGVNGAYYDVVSGIEKLEGLLPEDIGPDSPMAINCEYGSFDN 274
L Y DP T + ++ GTG N Y + I K +GLL M +N E+G+F +
Sbjct: 234 LSLGYYHDPDTVVAVVFGTGSNACYLERTDAIIKCQGLLT----TSGSMVVNMEWGNFWS 289
Query: 275 EHLVLPRTKYDVIIDEESPRPGQQAFEKMTSGYYLGEIMRLVLLDLYDSGFIFKDQDISK 334
H LPRT YD+ +D ES FEKM SG YLG+I+R V+L + + IF
Sbjct: 290 SH--LPRTSYDIDLDAESSNANDMGFEKMISGMYLGDIVRRVILRMSEDSDIFGPIS-PV 346
Query: 335 LKEAYVMDTSYPSKIEDDPFENLEDTDDLFKTNLNIETTVVERKLIRKLAELVGTRAARL 394
L E YV+ T+ S I +D L++ + K + + RKL+ K+ ++V RA RL
Sbjct: 347 LSEPYVLRTNSVSAIHEDDTPELQEVARILKDIGVSDVPLKVRKLVVKICDVVTRRAGRL 406
Query: 395 TVCGVSAICDKRG------------------YKTAHIAADGSVFNRYPGYKEKAAQALKD 436
G++ I K G K +A +G ++ Y ++E +AL +
Sbjct: 407 AAAGIAGILKKIGRDGSGGITSGRSRSEIQMQKRTVVAVEGGLYMNYTMFREYMEEALVE 466
Query: 437 IYNWDVEKMEDHPIQLVAAEDGSGVGAAIIACLTQ 471
I +V + + + A EDGS +G+A++ Q
Sbjct: 467 ILGEEVSQY----VVVKAMEDGSSIGSALLVASLQ 497
>At1g47840 [G] KOG1369 Hexokinase
Length = 493
Score = 239 bits (611), Expect = 5e-63
Identities = 151/443 (34%), Positives = 234/443 (52%), Gaps = 29/443 (6%)
Query: 41 MRSIVKHFISELDKGLSKKGG-NIPMIPGWVVEYPTGKETGDFLALDLGGTNLRVVLVKL 99
+R++ ++ GL+ +GG ++ MI +V P+G E G F ALDLGGTN RV V+L
Sbjct: 58 LRNVANAIADDMRDGLAVEGGGDLEMILTFVDALPSGNEEGLFYALDLGGTNFRVRSVQL 117
Query: 100 GGNHD--FDTTQNKYRLPDHLRTGTSEQLWSFIAKCLKEFVDEWYPDGV----SEPLPLG 153
GG + T + + L GTSE+L+ FIA L FV + P LG
Sbjct: 118 GGKKERVLATESEQISISQKLMIGTSEELFGFIASKLANFVAKEKPGRFLLEEGRKRELG 177
Query: 154 FTFSYPASQKKINSGVLQRWTKGFDIEGVEGHDVVPMLQEQIEKLNIPINVVALINDTTG 213
FTFS+P Q I+SG L +WTKGF + G+EG +VV L E +E + + V AL+ND G
Sbjct: 178 FTFSFPVKQTSIDSGTLSKWTKGFKVSGMEGKNVVACLNEAMEAHGLDMRVSALVNDGVG 237
Query: 214 TLVASLYTDPQTKMGIIIGTGVNGAYYDVVSGIEKLEGLLPEDIGPDSPMAINCEYGSFD 273
TL + Y D +G+I+GTG N Y + I KL IN E+G F
Sbjct: 238 TLAGARYWDEDVMVGVILGTGTNACYVEQKHAIPKLRSK-----SSSGTTIINTEWGGFS 292
Query: 274 NEHLVLPRTKYDVIIDEESPRPGQQAFEKMTSGYYLGEIMRLVLLDLYDSGFIFKDQDIS 333
+LP+T +D+ +DE S PG+ +EKM SG YLGEI+R VLL + ++ +F +
Sbjct: 293 K---ILPQTIFDLEMDETSLNPGEHLYEKMISGMYLGEIVRRVLLHMCETSDLFGHFAPA 349
Query: 334 KLKEAYVMDTSYPSKIEDDPFENLEDTDDLFKTNLNIETTVVERKLIRKLAELVGTRAAR 393
KL + T + K+++D ++L D + L+++ + R+ + ++ + V R R
Sbjct: 350 KLSTPLALRTEHLCKMQEDNTDDLRDVGSILYDFLDVKANMNARRRVVEVCDTVVKRGGR 409
Query: 394 LTVCGVSAICDK---------RGYKTAHIAADGSVFNRYPGYKEKAAQALKDIYNWDVEK 444
L G+ AI +K G +T +A DG+++ +YP Y++ AL ++ K
Sbjct: 410 LAGAGIVAILEKIEKDTKRMGSGKRTV-VAMDGALYEKYPQYRQYMQDALVELLG---HK 465
Query: 445 MEDHPIQLVAAEDGSGVGAAIIA 467
+ H + + +D SG+GAA++A
Sbjct: 466 LASH-VAIKHTKDVSGLGAALLA 487
>CE18823 [G] KOG1369 Hexokinase
Length = 552
Score = 239 bits (610), Expect = 7e-63
Identities = 158/477 (33%), Positives = 250/477 (52%), Gaps = 19/477 (3%)
Query: 5 GPKKPPARKGSMADVPANLMEQIHGLETL---FTVSSEKMRSIVKHFISELDKGLSK--K 59
G K P +A + + L E+ LE++ F +S+ +R ++ H +D+GL +
Sbjct: 22 GKKSPRTPTTPLAKMASKLNEESISLESVMAEFKLSNTTLRRMMSHLSDNMDRGLESGLE 81
Query: 60 GGNIPMIPGWVVEYPTGKETGDFLALDLGGTNLRVVLVKLGGNHDFDTTQNKYRLPDHLR 119
I M+P +V E P GKE G F+A+DLGGTNLRV+L++L T Q R+P+
Sbjct: 82 RSTIAMLPSFVPELPNGKERGKFVAMDLGGTNLRVMLMELEPGEPMRTKQFNTRMPNAAM 141
Query: 120 TGTSEQLWSFIAKCLKEFVDEWYPDGVSEPLPLGFTFSYPASQKKINSGVLQRWTKGFDI 179
GT ++L+ +IAK L +F+ E + E LP+GFTFSYP Q + S L RWTKG
Sbjct: 142 HGTGQKLFDYIAKALCDFLVE--RELADEHLPVGFTFSYPCDQTGLRSATLLRWTKGVTA 199
Query: 180 EGVEGHDVVPMLQEQIEK-LNIPINVVALINDTTGTLVASLY-TDPQTKMGIIIGTGVNG 237
G G DVV +L++ I + + +N+VALINDT GT+VA+ Y +G+IIGTG N
Sbjct: 200 TGCVGEDVVQLLEDAIARDGRVKVNIVALINDTVGTMVAAAYEAGGHCDIGVIIGTGTNA 259
Query: 238 AYYDVVSGIEKLEGLLPEDIGPDSPMAINCEYGSF-DNEHLVLPRTKYDVIIDEESPRPG 296
+Y + I ED S M I+ E+G F DN T+YD I+D +S PG
Sbjct: 260 SYMEDSRKIVHGLANATEDYNHKS-MIIDTEWGGFGDNGEADYIFTRYDKIVDSKSDHPG 318
Query: 297 QQAFEKMTSGYYLGEIMRLVLLDLYDSGFIFKDQDISKLKEAYVMDTSYPSKIEDDPFEN 356
+ +K+ +G +GE++RLVL L ++ +F L+ T Y S+I D
Sbjct: 319 VNSLDKLIAGMCMGELVRLVLERLCENKVLFNGIGSKMLRTRNTFPTKYISEILHDDCGV 378
Query: 357 LEDTDDLFKTNLNIE-TTVVERKLIRKLAELVGTRAARLTVCGVSAICDKRGYKTAHIAA 415
+T + L IE T + L+R++ +V R+A L ++ + ++ +A
Sbjct: 379 YSNTRQIM-DELGIEGATFSDMLLLREVCVVVSRRSANLAAAAIACVLNRVRRPNMLVAI 437
Query: 416 DGSVFNRYPGYKEKAAQALKDIYNWDVEKMEDHPIQLVAAEDGSGVGAAIIACLTQK 472
DGS + +P + + ++++ + ++ ++V DGSG GAA+IA + +
Sbjct: 438 DGSTYKYHPFFNHWVCEKIRELLDPGLD------FKIVQTGDGSGRGAALIAAIVSR 488
>At3g20040 [G] KOG1369 Hexokinase
Length = 488
Score = 236 bits (602), Expect = 6e-62
Identities = 150/438 (34%), Positives = 232/438 (52%), Gaps = 17/438 (3%)
Query: 40 KMRSIVKHFISELDKGLSKKGGN-IPMIPGWVVEYPTGKETGDFLALDLGGTNLRVVLVK 98
++R +V E+ GL +GG+ + M+ +V + P G ETG + AL LGG+ R++ V
Sbjct: 54 RLRQMVDAIAVEMQAGLVSEGGSKLKMLLTFVDDLPNGSETGTYYALHLGGSYFRIIKVH 113
Query: 99 LGGNHDFDTTQN--KYRLPDHLRTGTSEQLWSFIAKCLKEFVDEWYPD-GVSEPLP--LG 153
LGG Q+ ++ +P L TSE L+ F+A L+ F+++ D +S+PL L
Sbjct: 114 LGGQRSSLEVQDVERHSIPTSLMNSTSEVLFDFLASSLQRFIEKEGNDFSLSQPLKRELA 173
Query: 154 FTFSYPASQKKINSGVLQRWTKGFDIEGVEGHDVVPMLQEQIEKLNIPINVVALINDTTG 213
FTFS+P Q I+SGVL +WTKGF I + G D+ LQ + K + I V AL+NDT G
Sbjct: 174 FTFSFPVKQTSISSGVLIKWTKGFAISEMAGEDIAECLQGALNKRGLDIRVAALVNDTVG 233
Query: 214 TLVASLYTDPQTKMGIIIGTGVNGAYYDVVSGIEKLEGLLPEDIGPDSPMAINCEYGSFD 273
L + DP T ++ GTG N Y + I K + P M +N E+G+F
Sbjct: 234 ALSFGHFHDPDTIAAVVFGTGSNACYLERTDAIIKCQN--PRT--TSGSMVVNMEWGNFW 289
Query: 274 NEHLVLPRTKYDVIIDEESPRPGQQAFEKMTSGYYLGEIMRLVLLDLYDSGFIFKDQDIS 333
+ LPRT YD+ +D ES FEKM G YLG+I+R V+L + IF S
Sbjct: 290 SSR--LPRTSYDLELDAESMNSNDMGFEKMIGGMYLGDIVRRVILRMSQESDIFGPIS-S 346
Query: 334 KLKEAYVMDTSYPSKIEDDPFENLEDTDDLFKTNLNIETTVVERKLIRKLAELVGTRAAR 393
L +V+ T+ S + +D L++ + K E + RKL+ K+ ++V RAAR
Sbjct: 347 ILSTPFVLRTNSVSAMHEDDTSELQEVARILKDLGVSEVPMKVRKLVVKICDVVTRRAAR 406
Query: 394 LTVCGVSAICDKRGYKTAHIAADGSVFNRYPGYKEKAAQALKDIYNWDVEKMEDHPIQLV 453
L G++ I K+ + +A +G ++ Y ++E +AL+DI DV + + +
Sbjct: 407 LAAAGIAGILKKQIMRRTVVAVEGGLYLNYRMFREYMDEALRDILGEDVAQ----HVVVK 462
Query: 454 AAEDGSGVGAAIIACLTQ 471
A EDGS +G+A++ +Q
Sbjct: 463 AMEDGSSIGSALLLASSQ 480
>CE25610 [G] KOG1369 Hexokinase
Length = 451
Score = 197 bits (500), Expect = 4e-50
Identities = 138/463 (29%), Positives = 239/463 (50%), Gaps = 31/463 (6%)
Query: 23 LMEQIHGLETLFTVSSEKMRSIVKHFISELDKGLSK-KGGNIPMIPGWVVEYPTGKETGD 81
L ++ + F ++ E+++ I + ++ GL+K +G +I M+P +V P G ETG
Sbjct: 4 LPPEVEEILAKFRLNREQLQEISEKVEQQMKMGLAKTQGSSIAMLPSYVPALPDGTETGK 63
Query: 82 FLALDLGGTNLRVVLVKLGGNHDFDTTQN-KYRLPDHLRTGTSEQLWSFIAKCLKEFVDE 140
++A+DL G NLR++L+ + G T + Y + +H+ GT +QL++FI CL+ F+ E
Sbjct: 64 YVAIDLSGKNLRIMLLTMNGAGTTPTHETVNYIVANHVMKGTGDQLFTFIVNCLQRFLQE 123
Query: 141 WYPDGVSEPLPLGFTFSYPASQKKINSGVLQRWTKGFDIEGVEGHDVVPMLQEQIE-KLN 199
+ V LP+GF FSYP I S L WTKGFDI+ D+V +L+E +E ++
Sbjct: 124 F--GLVDANLPIGFVFSYPCELLSIRSARLLWWTKGFDIKDCLQRDIVALLEEALEMNMS 181
Query: 200 IPINVVALINDTTGTLVASLYT-DPQTKMGIIIGTGVNGAYYDVVSGIEKLEGLLPEDIG 258
+++ A++NDT G L A+ + P+ +G++IG G N +Y + S I K + + G
Sbjct: 182 TKVSIKAVMNDTVGQLAAAAHKYGPECTIGVVIGYGCNSSYLEKTSRITKFDA---KARG 238
Query: 259 PD-SPMAINCEYGSFDNE-HLVLPRTKYDVIIDEESPRPGQQAFEKMTSGYYLGEIMRLV 316
D M + E+ F L T++D +D S G+Q +K+ Y+GE++R V
Sbjct: 239 YDHDNMIVVTEWEEFGKHGELDDILTQFDREVDAASVHKGKQLIDKLCGALYIGEVVRRV 298
Query: 317 LLDLYDSGFIFKDQDISKLKEAYVMDTSYPSKIEDDPFENLEDTDDLFKTNLNI-ETTVV 375
L L +F+ Q KL E D S+P+K E L + + +FK I E V
Sbjct: 299 LSQLVLDRVLFEGQSCEKLDE----DESFPTKYIS---EILGEEEGVFKACRRICEELEV 351
Query: 376 ERK------LIRKLAELVGTRAARLTVCGVSAICDKRGYKTAHIAADGSVFNRYPGYKEK 429
E +IR++ +++ R A + +SA+ + I G++ +P Y +
Sbjct: 352 EMHGTGDYIIIREVCDVISRRGASIVAAAISALLRHLELSSVKIGVGGALIQFHPTYHQM 411
Query: 430 AAQALKDIYNWDVEKMEDHPIQLVAAEDGSGVGAAIIACLTQK 472
+ L+++ ++ +LV A++GS GAA+IA + ++
Sbjct: 412 LKEKLEELTPITMK------FELVPADEGSCQGAALIAAVAER 448
>Hs13376711 [G] KOG1369 Hexokinase
Length = 325
Score = 167 bits (423), Expect = 3e-41
Identities = 95/232 (40%), Positives = 136/232 (57%), Gaps = 7/232 (3%)
Query: 25 EQIHGLETLFTVSSEKMRSIVKHFISELDKGLSKKG---GNIPMIPGWVVEYPTGKETGD 81
+QI + LF ++ E++ + +EL+ GL KK + M+P +V P G E G
Sbjct: 57 KQIDRVLALFQLTREQLVDVQAKMRAELEYGLKKKSHGLATVRMLPTYVCGLPDGTEKGK 116
Query: 82 FLALDLGGTNLRVVLVKLGGNHDFDTTQNK-YRLPDHLRTGTSEQLWSFIAKCLKEFVDE 140
FLALDLGGTN RV+LVK+ NK + +P + GT E+L+ I +C+ +F+D
Sbjct: 117 FLALDLGGTNFRVLLVKIRSGRRSVRMYNKIFAIPLEIMQGTGEELFDHIVQCIADFLDY 176
Query: 141 WYPDGVSEPLPLGFTFSYPASQKKINSGVLQRWTKGFDIEGVEGHDVVPMLQEQIEKLN- 199
G S LPLGFTFS+P Q I+ G L WTKGF EG DVV ML+E I++ N
Sbjct: 177 MGLKGAS--LPLGFTFSFPCRQMSIDKGTLIGWTKGFKATDCEGEDVVDMLREAIKRRNE 234
Query: 200 IPINVVALINDTTGTLVASLYTDPQTKMGIIIGTGVNGAYYDVVSGIEKLEG 251
+++VA++NDT GT++ Y DP ++G+I GTG N Y + + IE +EG
Sbjct: 235 FDLDIVAVVNDTVGTMMTCGYEDPNCEIGLIAGTGSNMCYMEDMRNIEMVEG 286
>At4g37840 [G] KOG1369 Hexokinase
Length = 493
Score = 140 bits (353), Expect = 4e-33
Identities = 113/438 (25%), Positives = 214/438 (48%), Gaps = 21/438 (4%)
Query: 40 KMRSIVKHFISELDKGLSKKG-GNIPMIPGWVVEYPTGKETGDFLALDLGGTNLRVVLVK 98
K+ ++ ++++ L+ + G++ M+ + P+G E G ++L G L ++
Sbjct: 55 KLWAVADALVADMTASLTAECCGSLNMLVSFTGSLPSGDEKGVHYGVNLRGKELLLLRGT 114
Query: 99 LGGNHD--FDTTQNKYRLPDHLRTGTSEQLWSFIAKCLKEFVDEWYPDGVSEPLP-LGFT 155
LGGN + D +++ +PD + G+ ++L FI+ L +F+ P G +E + LGFT
Sbjct: 115 LGGNEEPISDVQKHEIPIPDDVLNGSFKELCDFISLELVKFL-AMNPGGEAEEVKNLGFT 173
Query: 156 FSYPASQKKINS-GVLQRWTKGFDIEGVEGHDVVPMLQEQIEKLNIPINV-VALINDTTG 213
+ Q +S + R + D + D+V + E +E + I + AL+++T G
Sbjct: 174 LTRSVEQIGSHSISSIHRKSLANDDDEKVLKDLVNDMNESLETHGLKIRMNTALVDNTIG 233
Query: 214 TLVASLYTDPQTKMGIIIGTGVNGAYYDVVSGIEKLEGLLPEDIGPDSPMAINCEYGSFD 273
L Y T + +G G N AY + I + + + E + ++ E+G F
Sbjct: 234 ELAGGRYYHKDTVAAVSLGMGTNAAYIEQAQEISRWKSAIREP----QEIVVSTEWGDFR 289
Query: 274 NEHLVLPRTKYDVIIDEESPRPGQQAFEKMTSGYYLGEIMRLVLLDLYDSGFIFKDQDIS 333
+ HL P T++D +D ES PG + FEKM SG YLGEI+R VLL + + +F D
Sbjct: 290 SCHL--PITEFDASLDAESLNPGHRIFEKMVSGRYLGEIVRRVLLKMSEESALFGDTLPP 347
Query: 334 KLKEAYVMDTSYPSKIEDDPFENLEDTDDLFKTNLNI-ETTVVERKLIRKLAELVGTRAA 392
KL Y++ + + + D E E + K I ++T+ R+++ ++ ++V RAA
Sbjct: 348 KLTIPYILWSPDMAAMHQDISEERETVNKKLKEVFGIMDSTLAAREVVVEVCDVVAERAA 407
Query: 393 RLTVCGVSAICDKRG---YKTAHIAADGSVFNRYPGYKEKAAQALKDIYNWDVEKMEDHP 449
RL G+ + K G K + + +G +++ Y ++ ++ ++ +++ DH
Sbjct: 408 RLAGAGIVGMIKKLGRLEKKMSIVIVEGGLYDHYRVFRNYLHSSVWEMLG---DELSDH- 463
Query: 450 IQLVAAEDGSGVGAAIIA 467
+ + + GS GA +A
Sbjct: 464 VVIEHSHGGSAAGALFLA 481
>At1g47860_3 [G] KOG1369 Hexokinase
Length = 318
Score = 80.1 bits (196), Expect = 7e-15
Identities = 53/153 (34%), Positives = 83/153 (53%), Gaps = 12/153 (7%)
Query: 265 INCEYGSFDNEHLVLPRTKYDVIIDEESPRPGQQAFEKMTSGYYLGEIMRLVLLDLYDSG 324
IN E+G F VLP+T +D +D ESP G+ +EKM SG YLGEI+R VLL + ++
Sbjct: 2 INTEWGGFSK---VLPQTIFDQEMDAESPNRGEHLYEKMVSGMYLGEIVRRVLLQMCETS 58
Query: 325 FIF-KDQDISKLKEAYVMDTSYPSKIEDDPFENLEDTDDLFKTNLNIETTVVERKLIRKL 383
+F + L + + + T + +K+++D TDDL L + + ER+ + ++
Sbjct: 59 DLFGQFVPGGNLSKPFALKTEHLNKMQED------TTDDLQTVGLVLYNILEERRRVVEV 112
Query: 384 AELVGTRAARLTVCGVSAICDKRGYK--TAHIA 414
+ V R RL GV+A ++G K HIA
Sbjct: 113 CDTVVKRGGRLAGAGVNARIKQKGIKPHVVHIA 145
>ECU11g1540 [G] KOG1369 Hexokinase
Length = 475
Score = 70.9 bits (172), Expect = 4e-12
Identities = 64/261 (24%), Positives = 117/261 (44%), Gaps = 32/261 (12%)
Query: 77 KETGDFLALDLGGTNLRV--VLVKLGGN--------HDF-DTTQNKYRLPDHLRTGTSEQ 125
+E+ L +D+GGT+L++ V++ LG + HD + + + YR PD ++
Sbjct: 82 QESRSVLVIDVGGTSLKISEVVIDLGSDEKGNSPSFHDIVECSPSFYRYPDTSGVSGQDR 141
Query: 126 L-WS-FIAKCLKEFVDEWYPDGVSEPLPLGFTFSYPASQKKINSGVLQRWTKGF---DIE 180
+ W+ ++A + EF P + TFSYP Q +N+ +++ TK F + E
Sbjct: 142 ISWNEWVADQVVEFYGRNPP---RSKVNASLTFSYPLIQTSVNNAQIKKTTKNFCFREDE 198
Query: 181 GVEGHDVVPMLQEQIEKLNIPINVVALINDTTGTLVASLYTDPQTKMGIIIGTGVNGAYY 240
D+V L + I + V ++ND+T T +A + + +GI++GTG N ++
Sbjct: 199 ATFTTDIVEALNSSLRSRKINVCVNCVLNDSTATYMAGVLRGYKNIIGIVLGTGTNSSFC 258
Query: 241 DVVSGIEKLEGLLPEDIGPDSPMAINCEYGSFDNEHLVLPRTKYDVIIDEESPRPGQQAF 300
V G + + N E+GS +L V++D E +
Sbjct: 259 -VKKG------------RSNEVVLYNSEWGSTRVPRSMLTEADLAVVVDLEMRKISHNII 305
Query: 301 EKMTSGYYLGEIMRLVLLDLY 321
+ + G LG+I+ L + Y
Sbjct: 306 DVLAGGCKLGDIVLHKLRNTY 326
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.317 0.138 0.403
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 30,740,307
Number of Sequences: 60738
Number of extensions: 1407154
Number of successful extensions: 3808
Number of sequences better than 1.0e-05: 30
Number of HSP's better than 0.0 without gapping: 29
Number of HSP's successfully gapped in prelim test: 1
Number of HSP's that attempted gapping in prelim test: 3564
Number of HSP's gapped (non-prelim): 39
length of query: 485
length of database: 30,389,216
effective HSP length: 110
effective length of query: 375
effective length of database: 23,708,036
effective search space: 8890513500
effective search space used: 8890513500
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)