ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIV2977 check: MH K KOG0666 Transcription Cyclin C-dependent kinase CDK8
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIV2977 1009021 1007243 -593
(593 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YPL042c [K] KOG0666 Cyclin C-dependent kinase CDK8 626 e-179
SPAC23H4.17c [K] KOG0666 Cyclin C-dependent kinase CDK8 338 1e-92
7294866 [K] KOG0666 Cyclin C-dependent kinase CDK8 241 2e-63
At5g63610 [K] KOG0666 Cyclin C-dependent kinase CDK8 238 2e-62
Hs4502745 [K] KOG0666 Cyclin C-dependent kinase CDK8 233 6e-61
Hs20551615 [K] KOG0666 Cyclin C-dependent kinase CDK8 221 3e-57
CE17815 [K] KOG0666 Cyclin C-dependent kinase CDK8 204 3e-52
Hs4557439 [R] KOG0594 Protein kinase PCTAIRE and related kinases 187 5e-47
CE18009 [R] KOG0594 Protein kinase PCTAIRE and related kinases 186 7e-47
Hs16936528 [R] KOG0594 Protein kinase PCTAIRE and related kinases 186 9e-47
At5g63370 [R] KOG0663 Protein kinase PITSLRE and related kinases 181 2e-45
YBR160w [R] KOG0594 Protein kinase PCTAIRE and related kinases 180 5e-45
Hs4502709 [R] KOG0594 Protein kinase PCTAIRE and related kinases 179 8e-45
CE00315 [R] KOG0594 Protein kinase PCTAIRE and related kinases 178 2e-44
At3g48750 [R] KOG0594 Protein kinase PCTAIRE and related kinases 177 4e-44
7300650 [R] KOG0594 Protein kinase PCTAIRE and related kinases 177 4e-44
7297680 [R] KOG0594 Protein kinase PCTAIRE and related kinases 175 2e-43
Hs16357496 [R] KOG0663 Protein kinase PITSLRE and related kinases 174 3e-43
Hs16332372 [R] KOG0663 Protein kinase PITSLRE and related kinases 174 3e-43
Hs16332370 [R] KOG0663 Protein kinase PITSLRE and related kinases 174 3e-43
Hs16332368 [R] KOG0663 Protein kinase PITSLRE and related kinases 174 3e-43
Hs16332366 [R] KOG0663 Protein kinase PITSLRE and related kinases 174 3e-43
Hs16332364 [R] KOG0663 Protein kinase PITSLRE and related kinases 174 3e-43
Hs16332362 [R] KOG0663 Protein kinase PITSLRE and related kinases 174 3e-43
Hs16332360 [R] KOG0663 Protein kinase PITSLRE and related kinases 174 3e-43
Hs16332358 [R] KOG0663 Protein kinase PITSLRE and related kinases 174 3e-43
Hs10835055 [R] KOG0663 Protein kinase PITSLRE and related kinases 174 3e-43
Hs16357494 [R] KOG0663 Protein kinase PITSLRE and related kinases 174 4e-43
Hs16357492 [R] KOG0663 Protein kinase PITSLRE and related kinases 174 4e-43
Hs4502743 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymera... 172 1e-42
Hs16357498 [R] KOG0663 Protein kinase PITSLRE and related kinases 172 1e-42
Hs16357486 [R] KOG0663 Protein kinase PITSLRE and related kinases 172 1e-42
Hs16357484 [R] KOG0663 Protein kinase PITSLRE and related kinases 172 1e-42
Hs16357482 [R] KOG0663 Protein kinase PITSLRE and related kinases 172 1e-42
Hs16357480 [R] KOG0663 Protein kinase PITSLRE and related kinases 172 1e-42
SPBC11B10.09 [R] KOG0594 Protein kinase PCTAIRE and related kinases 172 2e-42
Hs4502747 [D] KOG0669 Cyclin T-dependent kinase CDK9 172 2e-42
At1g18040 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymera... 171 3e-42
At5g10270 [D] KOG0600 Cdc2-related protein kinase 170 5e-42
7290565 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase... 170 5e-42
At1g73690 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymera... 170 6e-42
CE01761 [R] KOG0663 Protein kinase PITSLRE and related kinases 167 3e-41
YPL031c [R] KOG0594 Protein kinase PCTAIRE and related kinases 167 4e-41
At5g64960 [D] KOG0600 Cdc2-related protein kinase 167 4e-41
ECU02g1450 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymer... 167 5e-41
At1g67580 [R] KOG0663 Protein kinase PITSLRE and related kinases 166 7e-41
SPCC16C4.11 [R] KOG0594 Protein kinase PCTAIRE and related kinases 165 2e-40
Hs4826675 [UT] KOG0662 Cyclin-dependent kinase CDK5 164 4e-40
SPBC18H10.15 [R] KOG0663 Protein kinase PITSLRE and related kinases 164 5e-40
Hs4502731 [R] KOG0663 Protein kinase PITSLRE and related kinases 162 2e-39
At1g66750 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymera... 161 2e-39
Hs16950647 [R] KOG0663 Protein kinase PITSLRE and related kinases 161 3e-39
SPBC19F8.07 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polyme... 160 4e-39
7303051 [UT] KOG0662 Cyclin-dependent kinase CDK5 160 4e-39
SPAC2F3.15 [D] KOG0600 Cdc2-related protein kinase 159 9e-39
CE21213 [UT] KOG0662 Cyclin-dependent kinase CDK5 159 9e-39
At1g76540 [R] KOG0594 Protein kinase PCTAIRE and related kinases 159 9e-39
YDL108w [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase... 159 1e-38
CE03811 [R] KOG0663 Protein kinase PITSLRE and related kinases 158 3e-38
7303804 [R] KOG0663 Protein kinase PITSLRE and related kinases 158 3e-38
7291442 [D] KOG0669 Cyclin T-dependent kinase CDK9 156 1e-37
At1g20930 [R] KOG0594 Protein kinase PCTAIRE and related kinases 155 1e-37
Hs4505649 [R] KOG0594 Protein kinase PCTAIRE and related kinases 155 2e-37
7296346 [R] KOG0663 Protein kinase PITSLRE and related kinases 155 2e-37
ECU08g1920 [R] KOG0594 Protein kinase PCTAIRE and related kinases 154 4e-37
Hs5453860 [R] KOG0594 Protein kinase PCTAIRE and related kinases 154 5e-37
Hs15011928 [R] KOG0594 Protein kinase PCTAIRE and related kinases 154 5e-37
YKL139w [D] KOG0600 Cdc2-related protein kinase 153 8e-37
At2g38620 [R] KOG0594 Protein kinase PCTAIRE and related kinases 150 5e-36
7296451 [D] KOG0600 Cdc2-related protein kinase 150 5e-36
At4g13020 [T] KOG0661 MAPK related serine/threonine protein kinase 150 7e-36
At3g54180 [R] KOG0594 Protein kinase PCTAIRE and related kinases 150 7e-36
Hs6912584 [R] KOG0594 Protein kinase PCTAIRE and related kinases 149 2e-35
At4g11330 [T] KOG0660 Mitogen-activated protein kinase 148 2e-35
Hs4502741 [R] KOG0594 Protein kinase PCTAIRE and related kinases 147 3e-35
Hs14110390 [D] KOG0600 Cdc2-related protein kinase 147 3e-35
Hs14110387 [D] KOG0600 Cdc2-related protein kinase 147 3e-35
At1g33770 [D] KOG0600 Cdc2-related protein kinase 147 3e-35
Hs7662388 [T] KOG0661 MAPK related serine/threonine protein kinase 147 4e-35
Hs7706549 [D] KOG0600 Cdc2-related protein kinase 147 6e-35
SPBC32H8.10 [D] KOG0600 Cdc2-related protein kinase 146 8e-35
Hs21040235 [R] KOG0594 Protein kinase PCTAIRE and related kinases 145 2e-34
CE26422 [D] KOG0600 Cdc2-related protein kinase 145 2e-34
At1g10210 [T] KOG0660 Mitogen-activated protein kinase 145 2e-34
YHR030c [T] KOG0660 Mitogen-activated protein kinase 144 3e-34
Hs7705551 [T] KOG0661 MAPK related serine/threonine protein kinase 144 3e-34
7297578 [T] KOG0661 MAPK related serine/threonine protein kinase 144 3e-34
Hs20986501 [T] KOG0660 Mitogen-activated protein kinase 144 5e-34
Hs20986497 [T] KOG0660 Mitogen-activated protein kinase 144 5e-34
CE26988 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase... 143 6e-34
CE12408 [T] KOG0661 MAPK related serine/threonine protein kinase 142 1e-33
At2g18170 [T] KOG0660 Mitogen-activated protein kinase 142 2e-33
At1g59580 [T] KOG0660 Mitogen-activated protein kinase 142 2e-33
7292375 [R] KOG0594 Protein kinase PCTAIRE and related kinases 142 2e-33
Hs11496279 [T] KOG0661 MAPK related serine/threonine protein kinase 140 4e-33
At4g36450 [T] KOG0660 Mitogen-activated protein kinase 140 4e-33
CE29612 [R] KOG0594 Protein kinase PCTAIRE and related kinases 140 5e-33
CE24971 [T] KOG0660 Mitogen-activated protein kinase 140 5e-33
CE01583 [T] KOG0660 Mitogen-activated protein kinase 140 5e-33
At3g59790 [T] KOG0660 Mitogen-activated protein kinase 140 7e-33
Hs4502735 [R] KOG0594 Protein kinase PCTAIRE and related kinases 139 9e-33
Hs16160923 [R] KOG0594 Protein kinase PCTAIRE and related kinases 139 1e-32
YPR161c [D] KOG0600 Cdc2-related protein kinase 138 2e-32
At1g74330 [D] KOG0600 Cdc2-related protein kinase 138 3e-32
Hs4758652 [R] KOG0593 Predicted protein kinase KKIAMRE 137 4e-32
SPBC119.08 [T] KOG0660 Mitogen-activated protein kinase 137 5e-32
At2g46070 [T] KOG0660 Mitogen-activated protein kinase 137 5e-32
Hs4507281 [R] KOG0593 Predicted protein kinase KKIAMRE 135 1e-31
CE29478 [T] KOG0664 Nemo-like MAPK-related serine/threonine prot... 135 1e-31
CE29477 [T] KOG0664 Nemo-like MAPK-related serine/threonine prot... 135 1e-31
CE29476 [T] KOG0664 Nemo-like MAPK-related serine/threonine prot... 135 1e-31
At4g19110 [T] KOG0661 MAPK related serine/threonine protein kinase 135 2e-31
Hs4506091 [T] KOG0660 Mitogen-activated protein kinase 134 3e-31
At1g18670 [D] KOG0600 Cdc2-related protein kinase 134 3e-31
At3g45640 [T] KOG0660 Mitogen-activated protein kinase 134 4e-31
SPAC24B11.06c [T] KOG0660 Mitogen-activated protein kinase 134 5e-31
At2g43790 [T] KOG0660 Mitogen-activated protein kinase 134 5e-31
At1g71530 [D] KOG0600 Cdc2-related protein kinase 134 5e-31
At5g39420 [D] KOG0600 Cdc2-related protein kinase 133 7e-31
At4g01370 [T] KOG0660 Mitogen-activated protein kinase 133 7e-31
Hs21237745 [T] KOG0665 Jun-N-terminal kinase (JNK) 133 9e-31
Hs21237742 [T] KOG0665 Jun-N-terminal kinase (JNK) 133 9e-31
At4g10010 [D] KOG0600 Cdc2-related protein kinase 133 9e-31
CE06686 [T] KOG0660 Mitogen-activated protein kinase 132 1e-30
HsM20070143 [T] KOG0665 Jun-N-terminal kinase (JNK) 132 1e-30
Hs21237739 [T] KOG0665 Jun-N-terminal kinase (JNK) 132 1e-30
Hs21237736 [T] KOG0665 Jun-N-terminal kinase (JNK) 132 1e-30
CE23826 [D] KOG0669 Cyclin T-dependent kinase CDK9 132 1e-30
CE18824 [D] KOG0669 Cyclin T-dependent kinase CDK9 132 1e-30
At5g45430 [T] KOG0661 MAPK related serine/threonine protein kinase 132 1e-30
At1g03740 [D] KOG0600 Cdc2-related protein kinase 132 1e-30
7295173 [T] KOG0664 Nemo-like MAPK-related serine/threonine prot... 132 1e-30
Hs20128774 [T] KOG0660 Mitogen-activated protein kinase 132 2e-30
Hs7706445 [T] KOG0664 Nemo-like MAPK-related serine/threonine pr... 131 3e-30
Hs4503069 [T] KOG0660 Mitogen-activated protein kinase 131 3e-30
Hs20986499 [T] KOG0660 Mitogen-activated protein kinase 131 3e-30
7302908 [R] KOG0594 Protein kinase PCTAIRE and related kinases 131 3e-30
At3g05050 [D] KOG0600 Cdc2-related protein kinase 131 3e-30
7301110 [T] KOG0660 Mitogen-activated protein kinase 131 3e-30
Hs20986529 [T] KOG0660 Mitogen-activated protein kinase 130 4e-30
Hs20986512 [T] KOG0660 Mitogen-activated protein kinase 130 4e-30
At5g44290 [D] KOG0600 Cdc2-related protein kinase 130 4e-30
At4g22940 [D] KOG0600 Cdc2-related protein kinase 130 4e-30
At1g07880 [T] KOG0660 Mitogen-activated protein kinase 130 4e-30
Hs20986531 [T] KOG0660 Mitogen-activated protein kinase 130 6e-30
Hs20562757 [T] KOG0660 Mitogen-activated protein kinase 129 1e-29
CE29073 [R] KOG0594 Protein kinase PCTAIRE and related kinases 129 1e-29
CE06779 [R] KOG0594 Protein kinase PCTAIRE and related kinases 129 1e-29
YLR113w [T] KOG0660 Mitogen-activated protein kinase 129 2e-29
At1g18150 [T] KOG0660 Mitogen-activated protein kinase 129 2e-29
CE29020 [T] KOG0660 Mitogen-activated protein kinase 128 2e-29
CE02602_1 [T] KOG0660 Mitogen-activated protein kinase 127 4e-29
Hs7706059 [R] KOG0593 Predicted protein kinase KKIAMRE 127 5e-29
At3g14720 [T] KOG0660 Mitogen-activated protein kinase 127 5e-29
7298087 [T] KOG0660 Mitogen-activated protein kinase 127 5e-29
CE29318 [T] KOG0660 Mitogen-activated protein kinase 127 6e-29
At1g53050 [D] KOG0600 Cdc2-related protein kinase 127 6e-29
Hs4506085 [T] KOG0660 Mitogen-activated protein kinase 126 8e-29
Hs4506081 [T] KOG0665 Jun-N-terminal kinase (JNK) 126 8e-29
Hs20986510 [T] KOG0665 Jun-N-terminal kinase (JNK) 126 8e-29
Hs20986506 [T] KOG0665 Jun-N-terminal kinase (JNK) 126 8e-29
ECU11g0960 [D] KOG0600 Cdc2-related protein kinase 126 8e-29
CE27574 [T] KOG0665 Jun-N-terminal kinase (JNK) 126 1e-28
CE20258 [R] KOG0593 Predicted protein kinase KKIAMRE 125 1e-28
At2g01450 [T] KOG0660 Mitogen-activated protein kinase 125 1e-28
YPR054w [T] KOG0660 Mitogen-activated protein kinase 125 2e-28
At5g19010 [T] KOG0660 Mitogen-activated protein kinase 125 2e-28
At3g18040 [T] KOG0660 Mitogen-activated protein kinase 125 2e-28
At1g54610 [D] KOG0600 Cdc2-related protein kinase 124 4e-28
ECU08g1790 [D] KOG0600 Cdc2-related protein kinase 124 5e-28
CE28918 [R] KOG0594 Protein kinase PCTAIRE and related kinases 123 7e-28
CE18608 [R] KOG0594 Protein kinase PCTAIRE and related kinases 123 7e-28
At5g50860 [D] KOG0600 Cdc2-related protein kinase 123 7e-28
7297009 [R] KOG0593 Predicted protein kinase KKIAMRE 123 7e-28
SPAC31G5.09c [T] KOG0660 Mitogen-activated protein kinase 123 9e-28
YKL161c [T] KOG0660 Mitogen-activated protein kinase 122 2e-27
YGR040w [T] KOG0660 Mitogen-activated protein kinase 121 3e-27
Hs4506089 [T] KOG0660 Mitogen-activated protein kinase 121 3e-27
Hs4505569 [R] KOG0593 Predicted protein kinase KKIAMRE 120 4e-27
Hs4506785 [T] KOG0660 Mitogen-activated protein kinase 120 6e-27
At1g73670 [T] KOG0660 Mitogen-activated protein kinase 120 6e-27
At1g53510 [T] KOG0660 Mitogen-activated protein kinase 120 8e-27
7297631 [T] KOG0665 Jun-N-terminal kinase (JNK) 120 8e-27
Hs16936530 [R] KOG0594 Protein kinase PCTAIRE and related kinases 119 1e-26
Hs4506095 [T] KOG0665 Jun-N-terminal kinase (JNK) 119 2e-26
Hs20986523 [T] KOG0665 Jun-N-terminal kinase (JNK) 119 2e-26
ECU08g0230 [R] KOG0594 Protein kinase PCTAIRE and related kinases 118 2e-26
Hs7657498 [T] KOG0661 MAPK related serine/threonine protein kinase 117 4e-26
At1g09600 [D] KOG0600 Cdc2-related protein kinase 117 4e-26
Hs20986521 [T] KOG0665 Jun-N-terminal kinase (JNK) 117 5e-26
Hs20986519 [T] KOG0665 Jun-N-terminal kinase (JNK) 117 5e-26
At2g42880 [T] KOG0660 Mitogen-activated protein kinase 117 5e-26
CE11556 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase... 115 1e-25
SPBPI064 [G] KOG0658 Glycogen synthase kinase-3 115 2e-25
SPBC8D2.01 [G] KOG0658 Glycogen synthase kinase-3 115 2e-25
Hs17452757 [UT] KOG0662 Cyclin-dependent kinase CDK5 115 2e-25
CE29466 [T] KOG0665 Jun-N-terminal kinase (JNK) 115 2e-25
CE06762 [T] KOG0660 Mitogen-activated protein kinase 114 4e-25
Hs7106269 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymera... 114 5e-25
YJL106w [T] KOG0661 MAPK related serine/threonine protein kinase 112 2e-24
ECU11g1290 [R] KOG0663 Protein kinase PITSLRE and related kinases 112 2e-24
CE17062 [T] KOG0660 Mitogen-activated protein kinase 112 2e-24
7300773 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase... 112 2e-24
At4g18710 [G] KOG0658 Glycogen synthase kinase-3 112 2e-24
Hs21361340 [G] KOG0658 Glycogen synthase kinase-3 111 3e-24
CE17305 [T] KOG0665 Jun-N-terminal kinase (JNK) 111 3e-24
Hs20986514 [T] KOG0660 Mitogen-activated protein kinase 111 4e-24
Hs20986508 [T] KOG0665 Jun-N-terminal kinase (JNK) 110 5e-24
CE27220 [T] KOG0660 Mitogen-activated protein kinase 109 1e-23
SPAC3C7.06c [T] KOG0661 MAPK related serine/threonine protein ki... 109 1e-23
SPAC1687.15 [G] KOG0658 Glycogen synthase kinase-3 109 1e-23
Hs22051130 [G] KOG0658 Glycogen synthase kinase-3 109 1e-23
Hs11995474 [G] KOG0658 Glycogen synthase kinase-3 109 1e-23
YBL016w [T] KOG0660 Mitogen-activated protein kinase 108 2e-23
HsM4504163 [G] KOG0658 Glycogen synthase kinase-3 108 3e-23
Hs20986516 [T] KOG0660 Mitogen-activated protein kinase 107 4e-23
At3g05840 [G] KOG0658 Glycogen synthase kinase-3 107 4e-23
At1g57700 [D] KOG0600 Cdc2-related protein kinase 107 5e-23
At1g06390 [G] KOG0658 Glycogen synthase kinase-3 107 5e-23
At5g26751 [G] KOG0658 Glycogen synthase kinase-3 107 7e-23
At3g61160 [G] KOG0658 Glycogen synthase kinase-3 106 9e-23
7290342 [G] KOG0658 Glycogen synthase kinase-3 106 9e-23
CE21401 [G] KOG0658 Glycogen synthase kinase-3 104 3e-22
ECU07g1270 [G] KOG0658 Glycogen synthase kinase-3 104 4e-22
7291043 [T] KOG0660 Mitogen-activated protein kinase 104 4e-22
At2g30980 [G] KOG0658 Glycogen synthase kinase-3 103 7e-22
Hs17461944 [R] KOG0593 Predicted protein kinase KKIAMRE 103 1e-21
Hs19923407 [D] KOG0591 NIMA (never in mitosis)-related G2-specif... 102 2e-21
At1g57870 [G] KOG0658 Glycogen synthase kinase-3 102 2e-21
Hs16306492 [R] KOG0594 Protein kinase PCTAIRE and related kinases 101 3e-21
At1g09840 [G] KOG0658 Glycogen synthase kinase-3 100 5e-21
CE08727 [G] KOG0658 Glycogen synthase kinase-3 100 1e-20
YNL307c [G] KOG0658 Glycogen synthase kinase-3 99 1e-20
SPBC8D2.19 [T] KOG0661 MAPK related serine/threonine protein kinase 98 3e-20
Hs19424132 [D] KOG0591 NIMA (never in mitosis)-related G2-specif... 98 3e-20
At5g14640 [G] KOG0658 Glycogen synthase kinase-3 98 3e-20
YMR139w [G] KOG0658 Glycogen synthase kinase-3 98 4e-20
CE19219 [T] KOG0665 Jun-N-terminal kinase (JNK) 96 1e-19
At4g00720 [G] KOG0658 Glycogen synthase kinase-3 96 2e-19
CE20405 [G] KOG0658 Glycogen synthase kinase-3 95 3e-19
Hs20502986 [T] KOG0660 Mitogen-activated protein kinase 94 4e-19
YOL128c [G] KOG0658 Glycogen synthase kinase-3 93 1e-18
CE03232 [D] KOG0591 NIMA (never in mitosis)-related G2-specific ... 93 1e-18
Hs18552621 [R] KOG0597 Serine-threonine protein kinase FUSED 90 8e-18
CE23001 [R] KOG0589 Serine/threonine protein kinase 90 1e-17
Hs4503429 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 89 1e-17
CE19302_1 [G] KOG0658 Glycogen synthase kinase-3 89 2e-17
7290841 [D] KOG0591 NIMA (never in mitosis)-related G2-specific ... 88 4e-17
At3g08720 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 87 5e-17
ECU05g1510 [TDK] KOG0668 Casein kinase II alpha subunit 87 7e-17
At3g07980 [T] KOG0198 MEKK and related serine/threonine protein ... 87 7e-17
At3g08730 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 86 1e-16
CE05377 [G] KOG0658 Glycogen synthase kinase-3 86 2e-16
At1g50230 [R] KOG0597 Serine-threonine protein kinase FUSED 86 2e-16
CE23605 [T] KOG0665 Jun-N-terminal kinase (JNK) 86 2e-16
CE00847 [T] KOG0583 Serine/threonine protein kinase 86 2e-16
CE24761 [D] KOG0580 Serine/threonine protein kinase 85 4e-16
CE05866 [G] KOG0658 Glycogen synthase kinase-3 84 6e-16
At2g40120 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 84 6e-16
SPAC2F7.03c [R] KOG0667 Dual-specificity tyrosine-phosphorylatio... 83 1e-15
SPAC1E11.03 [R] KOG0667 Dual-specificity tyrosine-phosphorylatio... 83 1e-15
CE09532 [G] KOG0658 Glycogen synthase kinase-3 83 1e-15
SPBC21.06c [T] KOG0198 MEKK and related serine/threonine protein... 83 1e-15
Hs4758016 [D] KOG0575 Polo-like serine/threonine protein kinase 83 1e-15
At5g35980 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 83 1e-15
SPAC23C11.16 [D] KOG0575 Polo-like serine/threonine protein kinase 82 3e-15
Hs5922004 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 82 3e-15
Hs4503427 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 82 3e-15
At3g13530 [T] KOG0198 MEKK and related serine/threonine protein ... 82 3e-15
YDL079c [G] KOG0658 Glycogen synthase kinase-3 81 4e-15
CE24993 [D] KOG0669 Cyclin T-dependent kinase CDK9 81 4e-15
At3g44200 [R] KOG0589 Serine/threonine protein kinase 81 5e-15
SPAC890.03 [T] KOG0583 Serine/threonine protein kinase 80 7e-15
Hs9845489 [R] KOG0586 Serine/threonine protein kinase 80 7e-15
Hs9845487 [R] KOG0586 Serine/threonine protein kinase 80 7e-15
Hs5921999 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 80 7e-15
Hs22062450 [R] KOG0586 Serine/threonine protein kinase 80 7e-15
7301213 [R] KOG0589 Serine/threonine protein kinase 80 7e-15
YJL095w [T] KOG0198 MEKK and related serine/threonine protein ki... 79 1e-14
Hs8923922 [R] KOG0586 Serine/threonine protein kinase 79 1e-14
7293496 [R] KOG0597 Serine-threonine protein kinase FUSED 79 1e-14
Hs7661994 [T] KOG0579 Ste20-like serine/threonine protein kinase 79 2e-14
Hs4503095 [TDK] KOG0668 Casein kinase II alpha subunit 79 2e-14
CE26649 [D] KOG0575 Polo-like serine/threonine protein kinase 79 2e-14
At3g17750 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 79 2e-14
YOR231w [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K) 79 3e-14
SPCC320.12c [D] KOG0580 Serine/threonine protein kinase 79 3e-14
Hs13569922 [R] KOG0611 Predicted serine/threonine protein kinase 79 3e-14
CE27768 [R] KOG0586 Serine/threonine protein kinase 79 3e-14
CE23838 [R] KOG0586 Serine/threonine protein kinase 79 3e-14
7293666 [D] KOG0575 Polo-like serine/threonine protein kinase 78 3e-14
YJL141c [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 78 4e-14
Hs7662170 [R] KOG0611 Predicted serine/threonine protein kinase 78 4e-14
Hs4507271 [T] KOG0583 Serine/threonine protein kinase 78 4e-14
Hs20547806 [R] KOG0589 Serine/threonine protein kinase 78 4e-14
At3g06030 [T] KOG0198 MEKK and related serine/threonine protein ... 78 4e-14
7299793 [T] KOG0583 Serine/threonine protein kinase 78 4e-14
7298004 [G] KOG0658 Glycogen synthase kinase-3 78 4e-14
7291778 [T] KOG0579 Ste20-like serine/threonine protein kinase 78 4e-14
7289880 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kin... 78 4e-14
Hs5922001 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 77 6e-14
At1g73460 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 77 6e-14
At1g73450 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 77 6e-14
YPL140c [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K) 77 7e-14
YER129w [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kin... 77 7e-14
Hs14916455 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 77 7e-14
7290249 [R] KOG0586 Serine/threonine protein kinase 77 7e-14
Hs19311016_1 [R] KOG0589 Serine/threonine protein kinase 77 7e-14
HsM4505103 [R] KOG0586 Serine/threonine protein kinase 77 1e-13
Hs14776113 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 77 1e-13
SPCC18B5.11c [D] KOG0615 Serine/threonine protein kinase Chk2 an... 76 1e-13
Hs21389587 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 76 1e-13
Hs13899225 [R] KOG0586 Serine/threonine protein kinase 76 2e-13
CE19749 [T] KOG0665 Jun-N-terminal kinase (JNK) 76 2e-13
CE04172 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 76 2e-13
At5g39440 [T] KOG0583 Serine/threonine protein kinase 76 2e-13
At3g53570 [T] KOG0671 LAMMER dual specificity kinases 76 2e-13
Hs4885209 [T] KOG0196 Tyrosine kinase EPH (ephrin) receptor family 75 2e-13
Hs4503097 [TDK] KOG0668 Casein kinase II alpha subunit 75 2e-13
ECU03g0980 [T] KOG0583 Serine/threonine protein kinase 75 2e-13
At3g21220 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 75 2e-13
YOR061w [TDK] KOG0668 Casein kinase II alpha subunit 75 3e-13
YDR477w [T] KOG0583 Serine/threonine protein kinase 75 3e-13
YDR283c [J] KOG1035 eIF-2alpha kinase GCN2 75 3e-13
SPAC9G1.02 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 an... 75 3e-13
Hs4759178 [D] KOG0580 Serine/threonine protein kinase 75 3e-13
CE22877 [D] KOG0575 Polo-like serine/threonine protein kinase 75 3e-13
At2g23080 [TDK] KOG0668 Casein kinase II alpha subunit 75 3e-13
Hs4502557 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 75 4e-13
Hs4502553 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 75 4e-13
Hs21361643 [T] KOG4717 Serine/threonine protein kinase 75 4e-13
Hs14770402 [R] KOG0586 Serine/threonine protein kinase 75 4e-13
At3g20860 [R] KOG0589 Serine/threonine protein kinase 75 4e-13
At3g01090 [T] KOG0583 Serine/threonine protein kinase 75 4e-13
7300559 [T] KOG4279 Serine/threonine protein kinase 75 4e-13
SPAC1D4.06c [R] KOG0594 Protein kinase PCTAIRE and related kinases 74 5e-13
Hs6031180 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and... 74 5e-13
Hs5803088 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and... 74 5e-13
Hs11140819 [T] KOG1151 Tousled-like protein kinase 74 5e-13
CE27410 [T] KOG0583 Serine/threonine protein kinase 74 5e-13
At4g28980 [R] KOG0594 Protein kinase PCTAIRE and related kinases 74 5e-13
7302464 [R] KOG0586 Serine/threonine protein kinase 74 5e-13
7289745 [TDK] KOG0668 Casein kinase II alpha subunit 74 5e-13
HsM4826916 [D] KOG0575 Polo-like serine/threonine protein kinase 74 6e-13
CE23751 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 74 6e-13
CE19878 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 74 6e-13
CE05897 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 74 6e-13
At4g24740 [T] KOG0671 LAMMER dual specificity kinases 74 6e-13
At1g51660 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 74 6e-13
7298142 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 74 6e-13
7297776 [D] KOG0580 Serine/threonine protein kinase 74 6e-13
YNL183c [D] KOG0590 Checkpoint kinase and related serine/threoni... 74 8e-13
Hs5453966 [T] KOG0583 Serine/threonine protein kinase 74 8e-13
CE25046 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 74 8e-13
7300778 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 74 8e-13
7296450 [D] KOG0575 Polo-like serine/threonine protein kinase 74 8e-13
YDL214c [D] KOG0590 Checkpoint kinase and related serine/threoni... 73 1e-12
Hs4507273 [D] KOG0580 Serine/threonine protein kinase 73 1e-12
Hs21359873 [D] KOG0575 Polo-like serine/threonine protein kinase 73 1e-12
At5g67380 [TDK] KOG0668 Casein kinase II alpha subunit 73 1e-12
At1g54960 [T] KOG0198 MEKK and related serine/threonine protein ... 73 1e-12
7299438 [R] KOG0586 Serine/threonine protein kinase 73 1e-12
SPBC543.07 [T] KOG0581 Mitogen-activated protein kinase kinase (... 73 1e-12
Hs5730055 [D] KOG0575 Polo-like serine/threonine protein kinase 73 1e-12
Hs4758702 [T] KOG4279 Serine/threonine protein kinase 73 1e-12
Hs4505373 [V] KOG1826 Ras GTPase activating protein RasGAP/neuro... 73 1e-12
Hs20545245 [D] KOG0588 Serine/threonine protein kinase 73 1e-12
Hs20479818 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 73 1e-12
CE21879 [D] KOG0590 Checkpoint kinase and related serine/threoni... 73 1e-12
At1g09000 [T] KOG0198 MEKK and related serine/threonine protein ... 73 1e-12
Hs5031975 [T] KOG0578 p21-activated serine/threonine protein kinase 72 2e-12
CE25798 [T] KOG4257 Focal adhesion tyrosine kinase FAK contains ... 72 2e-12
CE19223 [T] KOG0582 Ste20-like serine/threonine protein kinase 72 2e-12
CE01612 [G] KOG0658 Glycogen synthase kinase-3 72 2e-12
YPL209c [D] KOG0580 Serine/threonine protein kinase 72 2e-12
YOL100w [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 72 2e-12
YDR523c [T] KOG0201 Serine/threonine protein kinase 72 2e-12
SPBC106.10 [T] KOG0616 cAMP-dependent protein kinase catalytic s... 72 2e-12
CE23883 [T] KOG4278 Protein tyrosine kinase 72 2e-12
CE21080 [T] KOG4278 Protein tyrosine kinase 72 2e-12
CE03506 [T] KOG4278 Protein tyrosine kinase 72 2e-12
At3g49370 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 72 2e-12
At3g29160 [T] KOG0583 Serine/threonine protein kinase 72 2e-12
7291037 [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K) 72 2e-12
7290150 [T] KOG0583 Serine/threonine protein kinase 72 2e-12
SPAC57A10.02 [D] KOG0588 Serine/threonine protein kinase 72 3e-12
SPAC23C11.11 [TDK] KOG0668 Casein kinase II alpha subunit 72 3e-12
HsM8923212 [T] KOG4717 Serine/threonine protein kinase 72 3e-12
Hs9966875 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 72 3e-12
Hs4505785 [G] KOG0599 Phosphorylase kinase gamma subunit 72 3e-12
Hs14196445 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 72 3e-12
At1g54510 [R] KOG0589 Serine/threonine protein kinase 72 3e-12
7293601 [T] KOG0577 Serine/threonine protein kinase 72 3e-12
Hs4507277_1 [R] KOG0589 Serine/threonine protein kinase 72 3e-12
YPL153c [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 71 4e-12
SPAC1F3.02c [T] KOG0198 MEKK and related serine/threonine protei... 71 4e-12
Hs5174547 [T] KOG4279 Serine/threonine protein kinase 71 4e-12
Hs4505153 [T] KOG0198 MEKK and related serine/threonine protein ... 71 4e-12
CE27177 [T] KOG4279 Serine/threonine protein kinase 71 4e-12
At3g50000 [TDK] KOG0668 Casein kinase II alpha subunit 71 4e-12
At2g37840 [OUT] KOG0595 Serine/threonine-protein kinase involved... 71 4e-12
7302570 [R] KOG0586 Serine/threonine protein kinase 71 4e-12
7299536 [D] KOG0580 Serine/threonine protein kinase 71 4e-12
SPCC74.03c [T] KOG0583 Serine/threonine protein kinase 71 5e-12
HsM5729922 [T] KOG0198 MEKK and related serine/threonine protein... 71 5e-12
At5g60550 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase k... 71 5e-12
At1g53570 [T] KOG0198 MEKK and related serine/threonine protein ... 71 5e-12
7294217 [D] KOG0588 Serine/threonine protein kinase 71 5e-12
YGL179c [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kin... 70 7e-12
YCR073c [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and r... 70 7e-12
YAR019c [T] KOG0198 MEKK and related serine/threonine protein ki... 70 7e-12
HsM7657627 [D] KOG0575 Polo-like serine/threonine protein kinase 70 7e-12
Hs5453964 [T] KOG0583 Serine/threonine protein kinase 70 7e-12
Hs21361433 [D] KOG0575 Polo-like serine/threonine protein kinase 70 7e-12
CE28479 [T] KOG0583 Serine/threonine protein kinase 70 7e-12
CE17321 [TDK] KOG0668 Casein kinase II alpha subunit 70 7e-12
At3g04810 [R] KOG0589 Serine/threonine protein kinase 70 7e-12
7291976 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 70 7e-12
YHL007c [T] KOG0578 p21-activated serine/threonine protein kinase 70 9e-12
YDR507c [D] KOG0588 Serine/threonine protein kinase 70 9e-12
SPBC4F6.06 [T] KOG0583 Serine/threonine protein kinase 70 9e-12
SPBC12D12.04c [T] KOG0694 Serine/threonine protein kinase 70 9e-12
Hs20545357 [T] KOG0583 Serine/threonine protein kinase 70 9e-12
CE21086 [D] KOG0590 Checkpoint kinase and related serine/threoni... 70 9e-12
CE18454 [T] KOG4717 Serine/threonine protein kinase 70 9e-12
7303211 [T] KOG4717 Serine/threonine protein kinase 70 9e-12
7290436 [T] KOG1151 Tousled-like protein kinase 70 9e-12
At4g12020_6 [T] KOG0198 MEKK and related serine/threonine protei... 70 9e-12
SPBC1D7.05c [T] KOG0198 MEKK and related serine/threonine protei... 70 1e-11
SPBC16E9.13 [T] KOG0583 Serine/threonine protein kinase 70 1e-11
Hs5174647 [T] KOG0197 Tyrosine kinases 70 1e-11
At4g38470 [T] KOG0192 Tyrosine kinase specific for activated (GT... 70 1e-11
YLR362w [T] KOG0198 MEKK and related serine/threonine protein ki... 69 2e-11
Hs17933758 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase ... 69 2e-11
At2g23070 [TDK] KOG0668 Casein kinase II alpha subunit 69 2e-11
YIL035c [TDK] KOG0668 Casein kinase II alpha subunit 69 2e-11
Hs20550209 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 69 2e-11
Hs14042966 [T] KOG0583 Serine/threonine protein kinase 69 2e-11
CE09248 [T] KOG0200 Fibroblast/platelet-derived growth factor re... 69 2e-11
At5g28290 [R] KOG0589 Serine/threonine protein kinase 69 2e-11
At3g61960 [OUT] KOG0595 Serine/threonine-protein kinase involved... 69 2e-11
At1g49180_1 [OUT] KOG0595 Serine/threonine-protein kinase involv... 69 2e-11
Hs4506529 [T] KOG0986 G protein-coupled receptor kinase 69 3e-11
At5g57630 [T] KOG0583 Serine/threonine protein kinase 69 3e-11
At5g35410 [T] KOG0583 Serine/threonine protein kinase 69 3e-11
7293761 [T] KOG4721 Serine/threonine protein kinase contains leu... 69 3e-11
CE27894_1 [R] KOG0589 Serine/threonine protein kinase 69 3e-11
YLR096w [T] KOG0583 Serine/threonine protein kinase 68 3e-11
YDR466w [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 68 3e-11
SPAC2C4.14c [T] KOG0201 Serine/threonine protein kinase 68 3e-11
CE15235 [R] KOG0589 Serine/threonine protein kinase 68 3e-11
7292679 [G] KOG0599 Phosphorylase kinase gamma subunit 68 3e-11
7291932 [A] KOG0670 U4/U6-associated splicing factor PRP4 68 3e-11
Hs19923464 [T] KOG0577 Serine/threonine protein kinase 68 4e-11
Hs18677726 [T] KOG1151 Tousled-like protein kinase 68 4e-11
Hs17999535 [A] KOG0670 U4/U6-associated splicing factor PRP4 68 4e-11
Hs13430860 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 68 4e-11
Hs11386209 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 68 4e-11
CE03492 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 68 4e-11
7304311 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 68 4e-11
7299322 [R] KOG0611 Predicted serine/threonine protein kinase 68 4e-11
YPL203w [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 67 6e-11
YMR001c [D] KOG0575 Polo-like serine/threonine protein kinase 67 6e-11
Hs5174701 [T] KOG0579 Ste20-like serine/threonine protein kinase 67 6e-11
Hs21729899 [T] KOG0581 Mitogen-activated protein kinase kinase (... 67 6e-11
Hs21729895 [T] KOG0581 Mitogen-activated protein kinase kinase (... 67 6e-11
Hs20547878 [R] KOG0589 Serine/threonine protein kinase 67 6e-11
CE28643 [T] KOG0583 Serine/threonine protein kinase 67 6e-11
CE07458 [T] KOG0583 Serine/threonine protein kinase 67 6e-11
CE04430 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 67 6e-11
CE01554 [T] KOG0986 G protein-coupled receptor kinase 67 6e-11
At5g66710 [T] KOG0192 Tyrosine kinase specific for activated (GT... 67 6e-11
YHR102w [T] KOG0201 Serine/threonine protein kinase 67 8e-11
Hs4758008 [T] KOG0671 LAMMER dual specificity kinases 67 8e-11
Hs14771959 [T] KOG0578 p21-activated serine/threonine protein ki... 67 8e-11
Hs14589909 [T] KOG0576 Mitogen-activated protein kinase kinase k... 67 8e-11
ECU11g1500 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 67 8e-11
At4g08500 [T] KOG0198 MEKK and related serine/threonine protein ... 67 8e-11
At2g17700 [T] KOG0192 Tyrosine kinase specific for activated (GT... 67 8e-11
YBL105c [T] KOG0694 Serine/threonine protein kinase 67 1e-10
SPCC1020.10 [D] KOG0590 Checkpoint kinase and related serine/thr... 67 1e-10
SPAC1D4.11c [T] KOG0671 LAMMER dual specificity kinases 67 1e-10
Hs4506101 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 67 1e-10
Hs21729897 [T] KOG0581 Mitogen-activated protein kinase kinase (... 67 1e-10
CE28251 [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 67 1e-10
CE27297 [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 67 1e-10
At4g31170 [T] KOG0192 Tyrosine kinase specific for activated (GT... 67 1e-10
At2g45490 [D] KOG0580 Serine/threonine protein kinase 67 1e-10
7299437 [R] KOG0586 Serine/threonine protein kinase 67 1e-10
YCL024w [T] KOG0583 Serine/threonine protein kinase 66 1e-10
Hs5032001 [T] KOG4257 Focal adhesion tyrosine kinase FAK contain... 66 1e-10
Hs4885563 [T] KOG0694 Serine/threonine protein kinase 66 1e-10
Hs22066219 [T] KOG1151 Tousled-like protein kinase 66 1e-10
Hs18581346 [T] KOG0660 Mitogen-activated protein kinase 66 1e-10
Hs15451902 [T] KOG0576 Mitogen-activated protein kinase kinase k... 66 1e-10
CE15475 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 66 1e-10
CE15473 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 66 1e-10
CE01146 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kin... 66 1e-10
At3g10540 [T] KOG0592 3-phosphoinositide-dependent protein kinas... 66 1e-10
7296749 [J] KOG1033 eIF-2alpha kinase PEK/EIF2AK3 66 1e-10
>YPL042c [K] KOG0666 Cyclin C-dependent kinase CDK8
Length = 555
Score = 626 bits (1615), Expect = e-179
Identities = 323/546 (59%), Positives = 390/546 (71%), Gaps = 53/546 (9%)
Query: 1 MYGNQQNNSNPYQMSYYRMNNGQGQGTNRWPQQLSHQEMLAGHSQQILNNNKPAGN-QSK 59
MY + N YQ Y R QGQ QQ +Q + G+ K
Sbjct: 1 MYNGKDRAQNSYQPMYQRPMQVQGQ------QQ----------AQSFVGKKNTIGSVHGK 44
Query: 60 PPIVMASNNVFSIGPYRQRKDSSRISVLQKYEIIGYIAAGTYGKVYKAKARDYQNGMNRD 119
P++MA+N+VF+IGPYR RKD R+SVL+KYE+IGYIAAGTYGKVYKAK R +G N
Sbjct: 45 APMLMANNDVFTIGPYRARKDRMRVSVLEKYEVIGYIAAGTYGKVYKAK-RQINSGTNSA 103
Query: 120 NVIILDSPDSV---------SADSNLDINSINRSTRQQEANDNLTTMDFRKPSHKRFTPP 170
N L+ ++ + S++D+ + + R+ D T + + + +P
Sbjct: 104 NGSSLNGTNAKIPQFDSTQPKSSSSMDMQANTNALRRNLLKDEGVTPGRIRTTREDVSPH 163
Query: 171 NNSNSTQIRSNSGSEXXXXXXXXXXXXXXXKPSQIQFYAIKKFKTEREGVE--HYTGISQ 228
NS + KP + FYAIKKFKTE++GVE HYTGISQ
Sbjct: 164 YNSQKQTL--------------------IKKPLTV-FYAIKKFKTEKDGVEQLHYTGISQ 202
Query: 229 SACREMSLCRELDNNHLTKLVEIFLEKKSIYMVSEFAEHDLLQIIHFHSHPEKRLIPPRM 288
SACREM+LCREL N HLT LVEIFLE+K ++MV E+AEHDLLQIIHFHSHPEKR+IPPRM
Sbjct: 203 SACREMALCRELHNKHLTTLVEIFLERKCVHMVYEYAEHDLLQIIHFHSHPEKRMIPPRM 262
Query: 289 LKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGCVKIGDLGLARKFNNMVQTLYTGD 348
++SIMWQ+LDGVSYLHQNW+LHRDLKPANIMVT+DGCVKIGDLGLARKF+NM+QTLYTGD
Sbjct: 263 VRSIMWQLLDGVSYLHQNWVLHRDLKPANIMVTIDGCVKIGDLGLARKFHNMLQTLYTGD 322
Query: 349 KVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELIGLRPIFKGEEAKMESKKSVLFQA 408
KV+VTIWYRAPEL+LGARHYTPA+DLW+VGCIFAELIGL+PIFKGEEAK++SKK+V FQ
Sbjct: 323 KVVVTIWYRAPELLLGARHYTPAVDLWSVGCIFAELIGLQPIFKGEEAKLDSKKTVPFQV 382
Query: 409 NQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPKYRDNLTAWYQTAGGKDKTALDILYR 468
NQ Q+ILEV+G+PD KIWP ++ YPEY Q+ K PKYRDNL WY +AGG+DK AL +LY
Sbjct: 383 NQLQRILEVLGTPDQKIWPYLEKYPEYDQITKFPKYRDNLATWYHSAGGRDKHALSLLYH 442
Query: 469 LLQYDPIKRIDAIDALDHVYFTNGDPPVCENVFEGLNYKYPPRRIHTNDNDITNVGN--- 525
LL YDPIKRIDA +AL+H YFT D PV ENVFEGL YKYP RRIHTNDNDI N+G+
Sbjct: 443 LLNYDPIKRIDAFNALEHKYFTESDIPVSENVFEGLTYKYPARRIHTNDNDIMNLGSRTK 502
Query: 526 DNNQAN 531
+N QA+
Sbjct: 503 NNTQAS 508
>SPAC23H4.17c [K] KOG0666 Cyclin C-dependent kinase CDK8
Length = 352
Score = 338 bits (868), Expect = 1e-92
Identities = 161/291 (55%), Positives = 214/291 (73%), Gaps = 5/291 (1%)
Query: 206 QFYAIKKFKTEREGVE---HYTGISQSACREMSLCRELDNNHLTKLVEIFLEKKSIYMVS 262
+ +AIKKFK E + V TG+SQSA REM LCRE+ + ++ LV++ L+ +I MV
Sbjct: 31 RLFAIKKFKAESKQVSSNAQQTGVSQSAIREMMLCREIQHENIVSLVQVLLKDGTISMVF 90
Query: 263 EFAEHDLLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTV 322
E+AEHDLLQIIHFHS R IPP +LKSI+WQI++GV+YLH+NWI+HRDLKPANIM+T
Sbjct: 91 EYAEHDLLQIIHFHSRSRTRQIPPSILKSILWQIINGVAYLHENWIMHRDLKPANIMITA 150
Query: 323 DGCVKIGDLGLARKFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFA 382
G VKIGDLGL R + + Y+ D+V+VTIWYRAPEL+LGA YTPAID+WA+GCI+
Sbjct: 151 TGKVKIGDLGLGRLIRDPILPFYSSDRVVVTIWYRAPELLLGAHDYTPAIDVWAIGCIYG 210
Query: 383 ELIGLRPIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMP 442
E++ L P+FKG+E KME KK V FQ+ Q +I+E++G+P + WP + +YPEY QL+
Sbjct: 211 EMLALSPLFKGDEIKMEDKKVVPFQSTQMLRIMELLGTPTEERWPGLKNYPEYYQLSSFE 270
Query: 443 -KYRDN-LTAWYQTAGGKDKTALDILYRLLQYDPIKRIDAIDALDHVYFTN 491
+Y +N L WYQT +D LD+L ++LQYDP RI A AL+HV+FT+
Sbjct: 271 VRYWNNLLPQWYQTVKNRDPQGLDLLMKMLQYDPKSRITAKQALEHVFFTS 321
>7294866 [K] KOG0666 Cyclin C-dependent kinase CDK8
Length = 531
Score = 241 bits (616), Expect = 2e-63
Identities = 144/351 (41%), Positives = 199/351 (56%), Gaps = 34/351 (9%)
Query: 212 KFKTEREGVEHY------TGISQSACREMSLCRELDNNHLTKLVEIFLEK--KSIYMVSE 263
K+K +G E+ TG+S SACRE++L REL + ++ L+ +FL + ++++ +
Sbjct: 116 KWKETSDGKEYALKQIDGTGLSMSACREIALLRELKHQNVITLIRVFLSHNDRKVFLLID 175
Query: 264 FAEHDLLQIIHFH---SHPEKRLIPPR-MLKSIMWQILDGVSYLHQNWILHRDLKPANIM 319
+AEHDL II FH +K+++ PR M+KS+++QILDG+ YLH NW+LHRDLKPANI+
Sbjct: 176 YAEHDLWHIIKFHRAAKATKKQVVVPRGMVKSLLYQILDGIHYLHSNWVLHRDLKPANIL 235
Query: 320 VTVDGC----VKIGDLGLARKFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLW 375
V DG VKI D+G AR FN ++ L D V+VT WYRAPEL+LGARHYT AID+W
Sbjct: 236 VMGDGNERGRVKIADMGFARLFNAPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIW 295
Query: 376 AVGCIFAELIGLRPIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEY 435
A+GCIFAEL+ PIF + + K S + +Q +I VMG P K W +I PE+
Sbjct: 296 AIGCIFAELLTSEPIFHCRQE--DIKTSNPYHHDQLDRIFNVMGFPQDKDWEDIKKMPEH 353
Query: 436 LQLAKMPKYRDNLTAWYQTAG----------GKDKTALDILYRLLQYDPIKRIDAIDALD 485
L K D + Y T D A +L +LL DP KRI + A+
Sbjct: 354 HTLTK-----DFKRSTYSTCSLAKYMERHKIKPDSKAFHLLQKLLLMDPNKRITSEQAMQ 408
Query: 486 HVYFTNGDPPVCENVFEGLNYKYPPRRIHTNDNDITNVGNDNNQANHSQKQ 536
YF +P ++VF G YP R T+D+ N Q Q+Q
Sbjct: 409 DQYFQE-EPQPTQDVFAGCPIPYPKREFLTDDDQEDKSDNKRQQQQQQQQQ 458
>At5g63610 [K] KOG0666 Cyclin C-dependent kinase CDK8
Length = 470
Score = 238 bits (606), Expect = 2e-62
Identities = 134/322 (41%), Positives = 196/322 (60%), Gaps = 24/322 (7%)
Query: 209 AIKKFKTEREGVEHYTGISQSACREMSLCRELDNNHLTKLVEIFLE--KKSIYMVSEFAE 266
AIKKFK ++G G+S +A RE+ L RE+ + ++ KLV + + S+Y+ ++AE
Sbjct: 53 AIKKFKQSKDG----DGVSPTAIREIMLLREISHENVVKLVNVHINFADMSLYLAFDYAE 108
Query: 267 HDLLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVD--- 323
+DL +II H + +KS++WQ+L+G++YLH NWI+HRDLKP+NI+V D
Sbjct: 109 YDLYEIIRHHRDKVGHSLNTYTVKSLLWQLLNGLNYLHSNWIIHRDLKPSNILVMGDAEE 168
Query: 324 -GCVKIGDLGLARKFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFA 382
G VKI D GLAR + ++ L + + V+VTIWYRAPEL+LG++HYT A+D+WAVGCIFA
Sbjct: 169 HGIVKIADFGLARIYQAPLKPL-SDNGVVVTIWYRAPELLLGSKHYTSAVDMWAVGCIFA 227
Query: 383 ELIGLRPIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEY---LQLA 439
EL+ L+P+F+G EAK FQ +Q KI +++G P WP + + P + +Q
Sbjct: 228 ELLTLKPLFQGAEAKSSQNP---FQLDQLDKIFKILGHPTMDKWPTLVNLPHWQNDVQHI 284
Query: 440 KMPKYRDNLTAWYQTAGGKDKTALDILYRLLQYDPIKRIDAIDALDHVYFTNGDPPVCEN 499
+ KY D++ + A D+L ++L+YDP+KRI A AL+H YF DP N
Sbjct: 285 QAHKY-DSVGLHNVVHLNQKSPAYDLLSKMLEYDPLKRITASQALEHEYF-RMDPLPGRN 342
Query: 500 VFEG-----LNYKYPPRRIHTN 516
F N YP R + TN
Sbjct: 343 AFVASQPMEKNVNYPTRPVDTN 364
>Hs4502745 [K] KOG0666 Cyclin C-dependent kinase CDK8
Length = 464
Score = 233 bits (594), Expect = 6e-61
Identities = 143/350 (40%), Positives = 199/350 (56%), Gaps = 40/350 (11%)
Query: 224 TGISQSACREMSLCRELDNNHLTKLVEIFLEK--KSIYMVSEFAEHDLLQIIHFH----S 277
TGIS SACRE++L REL + ++ L ++FL + ++++ ++AEHDL II FH +
Sbjct: 57 TGISMSACREIALLRELKHPNVISLQKVFLSHADRKVWLLFDYAEHDLWHIIKFHRASKA 116
Query: 278 HPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGC----VKIGDLGL 333
+ + +P M+KS+++QILDG+ YLH NW+LHRDLKPANI+V +G VKI D+G
Sbjct: 117 NKKPVQLPRGMVKSLLYQILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGF 176
Query: 334 ARKFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELIGLRPIFKG 393
AR FN+ ++ L D V+VT WYRAPEL+LGARHYT AID+WA+GCIFAEL+ PIF
Sbjct: 177 ARLFNSPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHC 236
Query: 394 EEAKMESKKSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPKYRDN------ 447
+ + K S + +Q +I VMG P K W +I PE+ L M +R N
Sbjct: 237 RQE--DIKTSNPYHHDQLDRIFNVMGFPADKDWEDIKKMPEHSTL--MKDFRRNTYTNCS 292
Query: 448 LTAWYQTAGGK-DKTALDILYRLLQYDPIKRIDAIDALDHVYFTNGDPPVCENVFEGLNY 506
L + + K D A +L +LL DPIKRI + A+ YF DP +VF G
Sbjct: 293 LIKYMEKHKVKPDSKAFHLLQKLLTMDPIKRITSEQAMQDPYFLE-DPLPTSDVFAGCQI 351
Query: 507 KYPPRRIHTND-----------------NDITNVGNDNNQ-ANHSQKQPM 538
YP R T + N G+ NQ ++H+Q P+
Sbjct: 352 PYPKREFLTEEEPDDKGDKKNQQQQQGNNHTNGTGHPGNQDSSHTQGPPL 401
>Hs20551615 [K] KOG0666 Cyclin C-dependent kinase CDK8
Length = 358
Score = 221 bits (562), Expect = 3e-57
Identities = 127/290 (43%), Positives = 173/290 (58%), Gaps = 17/290 (5%)
Query: 224 TGISQSACREMSLCRELDNNHLTKLVEIFLEK--KSIYMVSEFAEHDLLQIIHFH----S 277
TGIS SACRE++L REL + ++ L ++FL + ++++ ++AEHDL II FH +
Sbjct: 57 TGISMSACREIALLRELKHPNVIALQKVFLSHSDRKVWLLFDYAEHDLWHIIKFHRASKA 116
Query: 278 HPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGC----VKIGDLGL 333
+ + +P M+KS+++QILDG+ YLH NW+LHRDLKPANI+V +G VKI D+G
Sbjct: 117 NKKPMQLPRSMVKSLLYQILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGF 176
Query: 334 ARKFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELIGLRPIFKG 393
AR FN+ ++ L D V+VT WYRAPEL+LGARHYT AID+WA+GCIFAEL+ PIF
Sbjct: 177 ARLFNSPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHC 236
Query: 394 EEAKMESKKSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAK---MPKYRDNLTA 450
+ + K S F +Q +I VMG P K W +I PEY L K Y ++
Sbjct: 237 RQE--DIKTSNPFHHDQLDRIFSVMGFPADKDWEDIRKMPEYPTLQKDFRRTTYANSSLI 294
Query: 451 WYQTAG--GKDKTALDILYRLLQYDPIKRIDAIDALDHVYFTNGDPPVCE 498
Y D +L +LL DP KRI + AL YF P +
Sbjct: 295 KYMEKHKVKPDSKVFLLLQKLLTMDPTKRITSEQALQDPYFQEDPLPTLD 344
>CE17815 [K] KOG0666 Cyclin C-dependent kinase CDK8
Length = 622
Score = 204 bits (519), Expect = 3e-52
Identities = 112/305 (36%), Positives = 183/305 (59%), Gaps = 24/305 (7%)
Query: 225 GISQSACREMSLCRELDNNHLTKLVEIFL-EKKSIYMVSEFAEHDLLQIIHFHSHPEKR- 282
G S SACRE++L REL + +L L +FL +K ++++ ++AEHDL +I H + +
Sbjct: 66 GFSMSACREIALFRELRHPNLICLQRVFLTNEKKVWLLLDYAEHDLWHVIKHHRTAKSKK 125
Query: 283 ---LIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGC------VKIGDLGL 333
++P M+K+I++QIL G+ YLH NW+LHRDLKPANI++ DG VKI DLG
Sbjct: 126 VPIMVPRNMVKNILFQILSGMHYLHSNWVLHRDLKPANILLMGDGPPDMRGRVKIADLGF 185
Query: 334 ARKFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELIGLRPIFKG 393
+R + N ++ + D V+VT WYRAPEL+LGA+HYT AID+WA+GCIFAEL+ P+F
Sbjct: 186 SRIYANPLKPMAELDPVVVTFWYRAPELLLGAKHYTKAIDVWAIGCIFAELLTAEPLFFC 245
Query: 394 EEAKMESKKSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQL--------AKMPKYR 445
+E ++++ + +Q ++I ++G P WP++ P++ +L + +
Sbjct: 246 KEEDIKAQNP--YHYDQVKRIFHLLGYPSDADWPDMKKMPDHQRLLSDARNEGTPIQTFP 303
Query: 446 DNLTAWY-QTAGGKDKTALDILYRLLQYDPIKRIDAIDALDHVYFTNGDPPVCENVFEGL 504
++L ++ + + +L +LL DP KR+ +A++ +YF + P E + +
Sbjct: 304 NSLHRYFDKWKINSQSSPYRLLVKLLTVDPTKRVSCEEAMNDIYFRKMERPPRET--DDV 361
Query: 505 NYKYP 509
KYP
Sbjct: 362 FNKYP 366
>Hs4557439 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 305
Score = 187 bits (474), Expect = 5e-47
Identities = 102/290 (35%), Positives = 171/290 (58%), Gaps = 27/290 (9%)
Query: 206 QFYAIKKFKTEREGVEHYTGISQSACREMSLCRELDNNHLTKLVEIFLEKKSIYMVSEFA 265
Q A+KK + + E G+ +A RE+SL +EL + ++ +L+++ ++ +Y+V EF
Sbjct: 28 QLVALKKIRLDLE----MEGVPSTAIREISLLKELKHPNIVRLLDVVHNERKLYLVFEFL 83
Query: 266 EHDLLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGC 325
DL + + S P L P ++KS ++Q+L GVS+ H + ++HRDLKP N+++ G
Sbjct: 84 SQDLKK--YMDSTPGSEL-PLHLIKSYLFQLLQGVSFCHSHRVIHRDLKPQNLLINELGA 140
Query: 326 VKIGDLGLARKFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELI 385
+K+ D GLAR F ++T YT + +VT+WYRAPE++LG++ YT A+D+W++GCIFAE++
Sbjct: 141 IKLADFGLARAFGVPLRT-YTHE--VVTLWYRAPEILLGSKFYTTAVDIWSIGCIFAEMV 197
Query: 386 GLRPIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPKY- 444
+ +F G+ + +Q +I ++G+P WP + P+Y PK+
Sbjct: 198 TRKALFPGDS-----------EIDQLFRIFRMLGTPSEDTWPGVTQLPDY--KGSFPKWT 244
Query: 445 RDNLTAWYQTAGGKDKTALDILYRLLQYDPIKRIDAIDALDHVYFTNGDP 494
R L + + D+L +LLQYDP +RI A AL H YF++ +P
Sbjct: 245 RKGLE---EIVPNLEPEGRDLLMQLLQYDPSQRITAKTALAHPYFSSPEP 291
>CE18009 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 384
Score = 186 bits (473), Expect = 7e-47
Identities = 108/297 (36%), Positives = 169/297 (56%), Gaps = 38/297 (12%)
Query: 209 AIKKFKTEREGVEHYTGISQSACREMSLCRELDNNHLTKLVEI------------FLEKK 256
A+K +T+R+ GI + RE+S ++L ++++ L +I F EK
Sbjct: 72 ALKMIRTDRDE----EGIPSTCLREISCIKDLQHDNIVTLFDIIYASHFLNYNNIFFEKF 127
Query: 257 S----IYMVSEFAEHDLLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRD 312
S +YMV EF + DL ++ P ++PP +KS MWQ+L +SY H I+HRD
Sbjct: 128 SSNSKLYMVFEFIDRDLKNLLEM-LEPTNSVLPPNYVKSFMWQLLSALSYCHLRRIVHRD 186
Query: 313 LKPANIMVTVDGCVKIGDLGLARKFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAI 372
LKP NI+V+ G +KI D GLAR F + YT + +VT+WYR PE++LG++ Y+ ++
Sbjct: 187 LKPQNILVSDSGVIKIADFGLARNF-SFPSRNYTHE--VVTLWYRPPEILLGSQRYSTSL 243
Query: 373 DLWAVGCIFAELIGLRPIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHKIWPNIDSY 432
D+W++GCIF+E+ +P+F GE + +Q KI E++G+P+ K WP +DS+
Sbjct: 244 DMWSLGCIFSEIASNKPLFPGE-----------CEISQLFKIFEIVGTPNIKSWPGVDSF 292
Query: 433 PEYLQLAKMPKYRDNLTAWYQTAGGKDKTALDILYRLLQYDPIKRIDAIDALDHVYF 489
P Y A P++ NL +T+ LD+L +L+Y P +R+ A AL H YF
Sbjct: 293 PHY--KAVFPQWPVNLKKLEETS-CLTGNGLDVLREILRYPPERRLTAKGALSHRYF 346
>Hs16936528 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 298
Score = 186 bits (472), Expect = 9e-47
Identities = 101/293 (34%), Positives = 168/293 (56%), Gaps = 35/293 (11%)
Query: 209 AIKKFKTEREGVEHYTGISQSACREMSLCRELDNNHLTKLVEIFLEKKSIYMVSEFAEHD 268
A+KK + + E G+ +A RE+SL +EL++ ++ KL+++ + +Y+V EF D
Sbjct: 31 ALKKIRLDTET----EGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQD 86
Query: 269 LLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGCVKI 328
L + F IP ++KS ++Q+L G+++ H + +LHRDLKP N+++ +G +K+
Sbjct: 87 LKK---FMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKL 143
Query: 329 GDLGLARKFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELIGLR 388
D GLAR F V+T YT + +VT+WYRAPE++LG ++Y+ A+D+W++GCIFAE++ R
Sbjct: 144 ADFGLARAFGVPVRT-YTHE--VVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRR 200
Query: 389 PIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPKYRDNL 448
+F G+ + +Q +I +G+PD +WP + S MP Y+ +
Sbjct: 201 ALFPGDS-----------EIDQLFRIFRTLGTPDEVVWPGVTS---------MPDYKPSF 240
Query: 449 TAWYQTAGGK-----DKTALDILYRLLQYDPIKRIDAIDALDHVYFTNGDPPV 496
W + K D+ +L ++L YDP KRI A AL H +F + PV
Sbjct: 241 PKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPV 293
>At5g63370 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 612
Score = 181 bits (460), Expect = 2e-45
Identities = 108/316 (34%), Positives = 173/316 (54%), Gaps = 33/316 (10%)
Query: 206 QFYAIKKFKTEREGVEHYTGISQSACREMSLCRELDNNHLTKLVEIFLEKKS---IYMVS 262
+ A+KK K + + E G ++ RE+++ ++ + + E+ + K+ +YMV
Sbjct: 321 EIVALKKIKMKEDRFEEEYGFPLTSLREINILLSCNHPAIVNVKEVVVGGKNDNDVYMVM 380
Query: 263 EFAEHDLLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTV 322
E EHDL ++ P +K +M Q+LDG+ YLH NWI+HRDLKP+N+++
Sbjct: 381 EHLEHDLRGVMDRRKEP----FSTSEVKCLMMQLLDGLKYLHTNWIIHRDLKPSNLLMNN 436
Query: 323 DGCVKIGDLGLARKFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFA 382
G +KI D G+AR++ + ++ YT ++++T WYR PEL+LGA+ Y+ A+D+W+VGCI A
Sbjct: 437 CGELKICDFGMARQYGSPIKP-YT--QMVITQWYRPPELLLGAKEYSTAVDMWSVGCIMA 493
Query: 383 ELIGLRPIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMP 442
EL+ +P+F G+ + +Q QKI V+G+P+ IWP S+P AK P
Sbjct: 494 ELLSQKPLFPGKS-----------ELDQLQKIFAVLGTPNEAIWPGFSSFPN--AKAKFP 540
Query: 443 KYRDNLTAWYQTA----GGK--DKTALDILYRLLQYDPIKRIDAIDALDHVYFTNGDPPV 496
N+ A GG+ + D+L LL DP KR+ DAL+H +F P
Sbjct: 541 TQPYNMLRKKFPAISFVGGQILSERGFDLLNSLLTLDPEKRLTVEDALNHGWFHEVPLPK 600
Query: 497 CENVFEGLNYKYPPRR 512
++ YPP+R
Sbjct: 601 SKDFMP----TYPPKR 612
>YBR160w [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 298
Score = 180 bits (457), Expect = 5e-45
Identities = 106/291 (36%), Positives = 167/291 (56%), Gaps = 26/291 (8%)
Query: 201 KPSQIQ-FYAIKKFKTEREGVEHYTGISQSACREMSLCRELDNNHLTKLVEIF-LEKKSI 258
+P Q Q A+KK + E E G+ +A RE+SL +EL ++++ +L +I + +
Sbjct: 29 RPGQGQRVVALKKIRLESED----EGVPSTAIREISLLKELKDDNIVRLYDIVHSDAHKL 84
Query: 259 YMVSEFAEHDLLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANI 318
Y+V EF + DL + + P+ + + ++K M Q+ G++Y H + ILHRDLKP N+
Sbjct: 85 YLVFEFLDLDLKR--YMEGIPKDQPLGADIVKKFMMQLCKGIAYCHSHRILHRDLKPQNL 142
Query: 319 MVTVDGCVKIGDLGLARKFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVG 378
++ DG +K+GD GLAR F ++ YT + IVT+WYRAPE++LG + Y+ +D W++G
Sbjct: 143 LINKDGNLKLGDFGLARAFGVPLRA-YTHE--IVTLWYRAPEVLLGGKQYSTGVDTWSIG 199
Query: 379 CIFAELIGLRPIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQL 438
CIFAE+ +PIF G+ + +Q KI V+G+P+ IWP+I P++
Sbjct: 200 CIFAEMCNRKPIFSGDS-----------EIDQIFKIFRVLGTPNEAIWPDIVYLPDF--K 246
Query: 439 AKMPKYRDNLTAWYQTAGGKDKTALDILYRLLQYDPIKRIDAIDALDHVYF 489
P++R + Q D +D+L +LL YDPI RI A A H YF
Sbjct: 247 PSFPQWRRKDLS--QVVPSLDPRGIDLLDKLLAYDPINRISARRAAIHPYF 295
>Hs4502709 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 297
Score = 179 bits (455), Expect = 8e-45
Identities = 96/288 (33%), Positives = 167/288 (57%), Gaps = 24/288 (8%)
Query: 206 QFYAIKKFKTEREGVEHYTGISQSACREMSLCRELDNNHLTKLVEIFLEKKSIYMVSEFA 265
Q A+KK + E E G+ +A RE+SL +EL + ++ L ++ ++ +Y++ EF
Sbjct: 28 QVVAMKKIRLESEE----EGVPSTAIREISLLKELRHPNIVSLQDVLMQDSRLYLIFEFL 83
Query: 266 EHDLLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGC 325
DL + + S P + + ++KS ++QIL G+ + H +LHRDLKP N+++ G
Sbjct: 84 SMDLKK--YLDSIPPGQYMDSSLVKSYLYQILQGIVFCHSRRVLHRDLKPQNLLIDDKGT 141
Query: 326 VKIGDLGLARKFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELI 385
+K+ D GLAR F ++ +YT + +VT+WYR+PE++LG+ Y+ +D+W++G IFAEL
Sbjct: 142 IKLADFGLARAFGIPIR-VYTHE--VVTLWYRSPEVLLGSARYSTPVDIWSIGTIFAELA 198
Query: 386 GLRPIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPKYR 445
+P+F G+ + +Q +I +G+P++++WP ++S +Y PK++
Sbjct: 199 TKKPLFHGDS-----------EIDQLFRIFRALGTPNNEVWPEVESLQDYKN--TFPKWK 245
Query: 446 DNLTAWYQTAGGKDKTALDILYRLLQYDPIKRIDAIDALDHVYFTNGD 493
A + D+ LD+L ++L YDP KRI AL+H YF + D
Sbjct: 246 PGSLASH--VKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFNDLD 291
>CE00315 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 332
Score = 178 bits (452), Expect = 2e-44
Identities = 101/290 (34%), Positives = 166/290 (56%), Gaps = 27/290 (9%)
Query: 209 AIKKFKTEREGVEHYTGISQSACREMSLCRELDNNHLTKLVEIFLEKKSIYMVSEFAEHD 268
A+KK + E E G+ +A RE+SL +EL + ++ L + +++ ++++ EF D
Sbjct: 49 AMKKIRLESED----EGVPSTAVREISLLKELQHPNVVGLEAVIMQENRLFLIFEFLSFD 104
Query: 269 LLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGCVKI 328
L + + E +P LKS +QIL + + HQ ++HRDLKP N++V +G +K+
Sbjct: 105 LKRYMDQLGKDE--YLPLETLKSYTFQILQAMCFCHQRRVIHRDLKPQNLLVDNNGAIKL 162
Query: 329 GDLGLARKFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELIGLR 388
D GLAR ++ +YT + +VT+WYRAPE+++GA+ Y+ +D+W++GCIFAE+ +
Sbjct: 163 ADFGLARAIGIPIR-VYTHE--VVTLWYRAPEILMGAQRYSMGVDMWSIGCIFAEMATKK 219
Query: 389 PIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPKYRDNL 448
P+F+G+ + ++ +I V+G+P W ++S P+Y A PK+R+N
Sbjct: 220 PLFQGDS-----------EIDELFRIFRVLGTPTELEWNGVESLPDY--KATFPKWRENF 266
Query: 449 --TAWYQTAGGK---DKTALDILYRLLQYDPIKRIDAIDALDHVYFTNGD 493
+Y GK D TA +L LL YDP R++A AL H YF N D
Sbjct: 267 LRDKFYDKKTGKHLLDDTAFSLLEGLLIYDPSLRLNAKKALVHPYFDNMD 316
>At3g48750 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 294
Score = 177 bits (449), Expect = 4e-44
Identities = 103/284 (36%), Positives = 168/284 (58%), Gaps = 30/284 (10%)
Query: 209 AIKKFKTEREGVEHYTGISQSACREMSLCRELDNNHLTKLVEIFLEKKSIYMVSEFAEHD 268
A+KK + E+E G+ +A RE+SL +E+ ++++ K ++ +K +Y+V E+ + D
Sbjct: 31 ALKKIRLEQED----EGVPSTAIREISLLKEMQHSNIVKYDDVVHSEKRLYLVFEYLDLD 86
Query: 269 LLQIIHFHSHPE--KRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTV-DGC 325
L + H S P+ K L M+K+ ++QIL G++Y H + +LHRDLKP N+++
Sbjct: 87 LKK--HMDSTPDFSKDL---HMIKTYLYQILRGIAYCHSHRVLHRDLKPQNLLIDRRTNS 141
Query: 326 VKIGDLGLARKFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELI 385
+K+ D GLAR F V+T +T + +VT+WYRAPE++LG+ HY+ +D+W+VGCIFAE+I
Sbjct: 142 LKLADFGLARAFGIPVRT-FTHE--VVTLWYRAPEILLGSHHYSTPVDIWSVGCIFAEMI 198
Query: 386 GLRPIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPKYR 445
+P+F G+ + +Q KI +MG+P W + S P+Y + PK++
Sbjct: 199 SQKPLFPGDS-----------EIDQLFKIFRIMGTPYEDTWRGVTSLPDY--KSAFPKWK 245
Query: 446 DNLTAWYQTAGGKDKTALDILYRLLQYDPIKRIDAIDALDHVYF 489
T D +D+L ++L DP KRI+A AL+H YF
Sbjct: 246 P--TDLETFVPNLDPDGVDLLSKMLLMDPTKRINARAALEHEYF 287
>7300650 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 314
Score = 177 bits (449), Expect = 4e-44
Identities = 99/286 (34%), Positives = 160/286 (55%), Gaps = 28/286 (9%)
Query: 206 QFYAIKKFKTEREGVEHYTGISQSACREMSLCRELDNNHLTKLVEIFLEKKSIYMVSEFA 265
Q A+KK + E E G+ +A RE+SL + L + ++ +L ++ + ++YM+ E+
Sbjct: 32 QDVALKKIRLEGET----EGVPSTAIREISLLKNLKHPNVVQLFDVVISGNNLYMIFEYL 87
Query: 266 EHDLLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGC 325
DL +++ +K + P+++KS M QILD V + H N ILHRDLKP N++V G
Sbjct: 88 NMDLKKLMD----KKKDVFTPQLIKSYMHQILDAVGFCHTNRILHRDLKPQNLLVDTAGK 143
Query: 326 VKIGDLGLARKFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELI 385
+K+ D GLAR F N+ YT + +VT+WYRAPE++LG + Y+ +D+W++GCIF+E+I
Sbjct: 144 IKLADFGLARAF-NVPMRAYTHE--VVTLWYRAPEILLGTKFYSTGVDIWSLGCIFSEMI 200
Query: 386 GLRPIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPKYR 445
R +F G+ + +Q +I + +PD WP + P++ K P++
Sbjct: 201 MRRSLFPGDS-----------EIDQLYRIFRTLSTPDETNWPGVTQLPDF--KTKFPRWE 247
Query: 446 DNLTAWYQTAGGKDKTALDILYRLLQYDPIKRIDAIDALDHVYFTN 491
T + A +++ +L YDP RI A DAL H YF N
Sbjct: 248 GTNMPQPIT----EHEAHELIMSMLCYDPNLRISAKDALQHAYFRN 289
>7297680 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 297
Score = 175 bits (443), Expect = 2e-43
Identities = 92/284 (32%), Positives = 160/284 (55%), Gaps = 24/284 (8%)
Query: 206 QFYAIKKFKTEREGVEHYTGISQSACREMSLCRELDNNHLTKLVEIFLEKKSIYMVSEFA 265
Q A+KK + E + G+ +A RE+SL +EL + ++ L ++ +E+ IY++ EF
Sbjct: 28 QIVAMKKIRLESDD----EGVPSTAIREISLLKELKHENIVCLEDVLMEENRIYLIFEFL 83
Query: 266 EHDLLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGC 325
DL + + S P + + +++S ++QI + + H+ +LHRDLKP N+++ G
Sbjct: 84 SMDLKK--YMDSLPVDKHMESELVRSYLYQITSAILFCHRRRVLHRDLKPQNLLIDKSGL 141
Query: 326 VKIGDLGLARKFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELI 385
+K+ D GL R F V+ +YT + IVT+WYRAPE++LG+ Y+ +D+W++GCIFAE+
Sbjct: 142 IKVADFGLGRSFGIPVR-IYTHE--IVTLWYRAPEVLLGSPRYSCPVDIWSIGCIFAEMA 198
Query: 386 GLRPIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPKYR 445
+P+F+G+ + +Q ++ ++ +P IWP + S P+Y P +
Sbjct: 199 TRKPLFQGDS-----------EIDQLFRMFRILKTPTEDIWPGVTSLPDYKN--TFPCWS 245
Query: 446 DNLTAWYQTAGGKDKTALDILYRLLQYDPIKRIDAIDALDHVYF 489
N D +D++ ++L YDP+ RI A D L+H YF
Sbjct: 246 TNQLT--NQLKNLDANGIDLIQKMLIYDPVHRISAKDILEHPYF 287
>Hs16357496 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 439
Score = 174 bits (442), Expect = 3e-43
Identities = 101/310 (32%), Positives = 167/310 (53%), Gaps = 26/310 (8%)
Query: 206 QFYAIKKFKTEREGVEHYTGISQSACREMSLCRELDNNHLTKLVEIFLEKK--SIYMVSE 263
+ A+K+ K E+E G ++ RE++ + + ++ + EI + IY+V
Sbjct: 106 EIVALKRLKMEKEK----EGFPITSLREINTILKAQHPNIVTVREIVVGSNMDKIYIVMN 161
Query: 264 FAEHDLLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVD 323
+ EHDL ++ P P +K++M Q+L GV +LH NWILHRDLK +N++++
Sbjct: 162 YVEHDLKSLMETMKQP----FLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHA 217
Query: 324 GCVKIGDLGLARKFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAE 383
G +K+GD GLAR++ + ++ YT V+VT+WYRAPEL+LGA+ Y+ A+D+W+VGCIF E
Sbjct: 218 GILKVGDFGLAREYGSPLKA-YT--PVVVTLWYRAPELLLGAKEYSTAVDMWSVGCIFGE 274
Query: 384 LIGLRPIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPK 443
L+ +P+F G+ + +Q K+ + +G+P KIWP P ++
Sbjct: 275 LLTQKPLFPGKS-----------EIDQINKVFKDLGTPSEKIWPGYSELPAVKKMTFSEH 323
Query: 444 YRDNLTAWYQTAGGKDKTALDILYRLLQYDPIKRIDAIDALDHVYFTNGDPPVCENVFEG 503
+NL + D++ + L Y P +RI A D L H YF P+ ++F
Sbjct: 324 PYNNLRKRFGAL--LSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSMFPT 381
Query: 504 LNYKYPPRRI 513
K +R+
Sbjct: 382 WPAKSEQQRV 391
>Hs16332372 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 771
Score = 174 bits (442), Expect = 3e-43
Identities = 101/310 (32%), Positives = 167/310 (53%), Gaps = 26/310 (8%)
Query: 206 QFYAIKKFKTEREGVEHYTGISQSACREMSLCRELDNNHLTKLVEIFLEKK--SIYMVSE 263
+ A+K+ K E+E G ++ RE++ + + ++ + EI + IY+V
Sbjct: 438 EIVALKRLKMEKEK----EGFPITSLREINTILKAQHPNIVTVREIVVGSNMDKIYIVMN 493
Query: 264 FAEHDLLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVD 323
+ EHDL ++ P P +K++M Q+L GV +LH NWILHRDLK +N++++
Sbjct: 494 YVEHDLKSLMETMKQP----FLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHA 549
Query: 324 GCVKIGDLGLARKFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAE 383
G +K+GD GLAR++ + ++ YT V+VT+WYRAPEL+LGA+ Y+ A+D+W+VGCIF E
Sbjct: 550 GILKVGDFGLAREYGSPLKA-YT--PVVVTLWYRAPELLLGAKEYSTAVDMWSVGCIFGE 606
Query: 384 LIGLRPIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPK 443
L+ +P+F G+ + +Q K+ + +G+P KIWP P ++
Sbjct: 607 LLTQKPLFPGKS-----------EIDQINKVFKDLGTPSEKIWPGYSELPAVKKMTFSEH 655
Query: 444 YRDNLTAWYQTAGGKDKTALDILYRLLQYDPIKRIDAIDALDHVYFTNGDPPVCENVFEG 503
+NL + D++ + L Y P +RI A D L H YF P+ ++F
Sbjct: 656 PYNNLRKRFGAL--LSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSMFPT 713
Query: 504 LNYKYPPRRI 513
K +R+
Sbjct: 714 WPAKSEQQRV 723
>Hs16332370 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 780
Score = 174 bits (442), Expect = 3e-43
Identities = 101/310 (32%), Positives = 167/310 (53%), Gaps = 26/310 (8%)
Query: 206 QFYAIKKFKTEREGVEHYTGISQSACREMSLCRELDNNHLTKLVEIFLEKK--SIYMVSE 263
+ A+K+ K E+E G ++ RE++ + + ++ + EI + IY+V
Sbjct: 447 EIVALKRLKMEKEK----EGFPITSLREINTILKAQHPNIVTVREIVVGSNMDKIYIVMN 502
Query: 264 FAEHDLLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVD 323
+ EHDL ++ P P +K++M Q+L GV +LH NWILHRDLK +N++++
Sbjct: 503 YVEHDLKSLMETMKQP----FLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHA 558
Query: 324 GCVKIGDLGLARKFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAE 383
G +K+GD GLAR++ + ++ YT V+VT+WYRAPEL+LGA+ Y+ A+D+W+VGCIF E
Sbjct: 559 GILKVGDFGLAREYGSPLKA-YT--PVVVTLWYRAPELLLGAKEYSTAVDMWSVGCIFGE 615
Query: 384 LIGLRPIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPK 443
L+ +P+F G+ + +Q K+ + +G+P KIWP P ++
Sbjct: 616 LLTQKPLFPGKS-----------EIDQINKVFKDLGTPSEKIWPGYSELPAVKKMTFSEH 664
Query: 444 YRDNLTAWYQTAGGKDKTALDILYRLLQYDPIKRIDAIDALDHVYFTNGDPPVCENVFEG 503
+NL + D++ + L Y P +RI A D L H YF P+ ++F
Sbjct: 665 PYNNLRKRFGAL--LSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSMFPT 722
Query: 504 LNYKYPPRRI 513
K +R+
Sbjct: 723 WPAKSEQQRV 732
>Hs16332368 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 461
Score = 174 bits (442), Expect = 3e-43
Identities = 101/310 (32%), Positives = 167/310 (53%), Gaps = 26/310 (8%)
Query: 206 QFYAIKKFKTEREGVEHYTGISQSACREMSLCRELDNNHLTKLVEIFLEKK--SIYMVSE 263
+ A+K+ K E+E G ++ RE++ + + ++ + EI + IY+V
Sbjct: 128 EIVALKRLKMEKEK----EGFPITSLREINTILKAQHPNIVTVREIVVGSNMDKIYIVMN 183
Query: 264 FAEHDLLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVD 323
+ EHDL ++ P P +K++M Q+L GV +LH NWILHRDLK +N++++
Sbjct: 184 YVEHDLKSLMETMKQP----FLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHA 239
Query: 324 GCVKIGDLGLARKFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAE 383
G +K+GD GLAR++ + ++ YT V+VT+WYRAPEL+LGA+ Y+ A+D+W+VGCIF E
Sbjct: 240 GILKVGDFGLAREYGSPLKA-YT--PVVVTLWYRAPELLLGAKEYSTAVDMWSVGCIFGE 296
Query: 384 LIGLRPIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPK 443
L+ +P+F G+ + +Q K+ + +G+P KIWP P ++
Sbjct: 297 LLTQKPLFPGKS-----------EIDQINKVFKDLGTPSEKIWPGYSELPAVKKMTFSEH 345
Query: 444 YRDNLTAWYQTAGGKDKTALDILYRLLQYDPIKRIDAIDALDHVYFTNGDPPVCENVFEG 503
+NL + D++ + L Y P +RI A D L H YF P+ ++F
Sbjct: 346 PYNNLRKRFGAL--LSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSMFPT 403
Query: 504 LNYKYPPRRI 513
K +R+
Sbjct: 404 WPAKSEQQRV 413
>Hs16332366 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 565
Score = 174 bits (442), Expect = 3e-43
Identities = 101/310 (32%), Positives = 167/310 (53%), Gaps = 26/310 (8%)
Query: 206 QFYAIKKFKTEREGVEHYTGISQSACREMSLCRELDNNHLTKLVEIFLEKK--SIYMVSE 263
+ A+K+ K E+E G ++ RE++ + + ++ + EI + IY+V
Sbjct: 232 EIVALKRLKMEKEK----EGFPITSLREINTILKAQHPNIVTVREIVVGSNMDKIYIVMN 287
Query: 264 FAEHDLLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVD 323
+ EHDL ++ P P +K++M Q+L GV +LH NWILHRDLK +N++++
Sbjct: 288 YVEHDLKSLMETMKQP----FLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHA 343
Query: 324 GCVKIGDLGLARKFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAE 383
G +K+GD GLAR++ + ++ YT V+VT+WYRAPEL+LGA+ Y+ A+D+W+VGCIF E
Sbjct: 344 GILKVGDFGLAREYGSPLKA-YT--PVVVTLWYRAPELLLGAKEYSTAVDMWSVGCIFGE 400
Query: 384 LIGLRPIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPK 443
L+ +P+F G+ + +Q K+ + +G+P KIWP P ++
Sbjct: 401 LLTQKPLFPGKS-----------EIDQINKVFKDLGTPSEKIWPGYSELPAVKKMTFSEH 449
Query: 444 YRDNLTAWYQTAGGKDKTALDILYRLLQYDPIKRIDAIDALDHVYFTNGDPPVCENVFEG 503
+NL + D++ + L Y P +RI A D L H YF P+ ++F
Sbjct: 450 PYNNLRKRFGAL--LSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSMFPT 507
Query: 504 LNYKYPPRRI 513
K +R+
Sbjct: 508 WPAKSEQQRV 517
>Hs16332364 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 748
Score = 174 bits (442), Expect = 3e-43
Identities = 101/310 (32%), Positives = 167/310 (53%), Gaps = 26/310 (8%)
Query: 206 QFYAIKKFKTEREGVEHYTGISQSACREMSLCRELDNNHLTKLVEIFLEKK--SIYMVSE 263
+ A+K+ K E+E G ++ RE++ + + ++ + EI + IY+V
Sbjct: 415 EIVALKRLKMEKEK----EGFPITSLREINTILKAQHPNIVTVREIVVGSNMDKIYIVMN 470
Query: 264 FAEHDLLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVD 323
+ EHDL ++ P P +K++M Q+L GV +LH NWILHRDLK +N++++
Sbjct: 471 YVEHDLKSLMETMKQP----FLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHA 526
Query: 324 GCVKIGDLGLARKFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAE 383
G +K+GD GLAR++ + ++ YT V+VT+WYRAPEL+LGA+ Y+ A+D+W+VGCIF E
Sbjct: 527 GILKVGDFGLAREYGSPLKA-YT--PVVVTLWYRAPELLLGAKEYSTAVDMWSVGCIFGE 583
Query: 384 LIGLRPIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPK 443
L+ +P+F G+ + +Q K+ + +G+P KIWP P ++
Sbjct: 584 LLTQKPLFPGKS-----------EIDQINKVFKDLGTPSEKIWPGYSELPAVKKMTFSEH 632
Query: 444 YRDNLTAWYQTAGGKDKTALDILYRLLQYDPIKRIDAIDALDHVYFTNGDPPVCENVFEG 503
+NL + D++ + L Y P +RI A D L H YF P+ ++F
Sbjct: 633 PYNNLRKRFGAL--LSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSMFPT 690
Query: 504 LNYKYPPRRI 513
K +R+
Sbjct: 691 WPAKSEQQRV 700
>Hs16332362 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 737
Score = 174 bits (442), Expect = 3e-43
Identities = 101/310 (32%), Positives = 167/310 (53%), Gaps = 26/310 (8%)
Query: 206 QFYAIKKFKTEREGVEHYTGISQSACREMSLCRELDNNHLTKLVEIFLEKK--SIYMVSE 263
+ A+K+ K E+E G ++ RE++ + + ++ + EI + IY+V
Sbjct: 404 EIVALKRLKMEKEK----EGFPITSLREINTILKAQHPNIVTVREIVVGSNMDKIYIVMN 459
Query: 264 FAEHDLLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVD 323
+ EHDL ++ P P +K++M Q+L GV +LH NWILHRDLK +N++++
Sbjct: 460 YVEHDLKSLMETMKQP----FLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHA 515
Query: 324 GCVKIGDLGLARKFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAE 383
G +K+GD GLAR++ + ++ YT V+VT+WYRAPEL+LGA+ Y+ A+D+W+VGCIF E
Sbjct: 516 GILKVGDFGLAREYGSPLKA-YT--PVVVTLWYRAPELLLGAKEYSTAVDMWSVGCIFGE 572
Query: 384 LIGLRPIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPK 443
L+ +P+F G+ + +Q K+ + +G+P KIWP P ++
Sbjct: 573 LLTQKPLFPGKS-----------EIDQINKVFKDLGTPSEKIWPGYSELPAVKKMTFSEH 621
Query: 444 YRDNLTAWYQTAGGKDKTALDILYRLLQYDPIKRIDAIDALDHVYFTNGDPPVCENVFEG 503
+NL + D++ + L Y P +RI A D L H YF P+ ++F
Sbjct: 622 PYNNLRKRFGAL--LSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSMFPT 679
Query: 504 LNYKYPPRRI 513
K +R+
Sbjct: 680 WPAKSEQQRV 689
>Hs16332360 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 526
Score = 174 bits (442), Expect = 3e-43
Identities = 101/310 (32%), Positives = 167/310 (53%), Gaps = 26/310 (8%)
Query: 206 QFYAIKKFKTEREGVEHYTGISQSACREMSLCRELDNNHLTKLVEIFLEKK--SIYMVSE 263
+ A+K+ K E+E G ++ RE++ + + ++ + EI + IY+V
Sbjct: 193 EIVALKRLKMEKEK----EGFPITSLREINTILKAQHPNIVTVREIVVGSNMDKIYIVMN 248
Query: 264 FAEHDLLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVD 323
+ EHDL ++ P P +K++M Q+L GV +LH NWILHRDLK +N++++
Sbjct: 249 YVEHDLKSLMETMKQP----FLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHA 304
Query: 324 GCVKIGDLGLARKFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAE 383
G +K+GD GLAR++ + ++ YT V+VT+WYRAPEL+LGA+ Y+ A+D+W+VGCIF E
Sbjct: 305 GILKVGDFGLAREYGSPLKA-YT--PVVVTLWYRAPELLLGAKEYSTAVDMWSVGCIFGE 361
Query: 384 LIGLRPIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPK 443
L+ +P+F G+ + +Q K+ + +G+P KIWP P ++
Sbjct: 362 LLTQKPLFPGKS-----------EIDQINKVFKDLGTPSEKIWPGYSELPAVKKMTFSEH 410
Query: 444 YRDNLTAWYQTAGGKDKTALDILYRLLQYDPIKRIDAIDALDHVYFTNGDPPVCENVFEG 503
+NL + D++ + L Y P +RI A D L H YF P+ ++F
Sbjct: 411 PYNNLRKRFGAL--LSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSMFPT 468
Query: 504 LNYKYPPRRI 513
K +R+
Sbjct: 469 WPAKSEQQRV 478
>Hs16332358 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 782
Score = 174 bits (442), Expect = 3e-43
Identities = 101/310 (32%), Positives = 167/310 (53%), Gaps = 26/310 (8%)
Query: 206 QFYAIKKFKTEREGVEHYTGISQSACREMSLCRELDNNHLTKLVEIFLEKK--SIYMVSE 263
+ A+K+ K E+E G ++ RE++ + + ++ + EI + IY+V
Sbjct: 449 EIVALKRLKMEKEK----EGFPITSLREINTILKAQHPNIVTVREIVVGSNMDKIYIVMN 504
Query: 264 FAEHDLLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVD 323
+ EHDL ++ P P +K++M Q+L GV +LH NWILHRDLK +N++++
Sbjct: 505 YVEHDLKSLMETMKQP----FLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHA 560
Query: 324 GCVKIGDLGLARKFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAE 383
G +K+GD GLAR++ + ++ YT V+VT+WYRAPEL+LGA+ Y+ A+D+W+VGCIF E
Sbjct: 561 GILKVGDFGLAREYGSPLKA-YT--PVVVTLWYRAPELLLGAKEYSTAVDMWSVGCIFGE 617
Query: 384 LIGLRPIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPK 443
L+ +P+F G+ + +Q K+ + +G+P KIWP P ++
Sbjct: 618 LLTQKPLFPGKS-----------EIDQINKVFKDLGTPSEKIWPGYSELPAVKKMTFSEH 666
Query: 444 YRDNLTAWYQTAGGKDKTALDILYRLLQYDPIKRIDAIDALDHVYFTNGDPPVCENVFEG 503
+NL + D++ + L Y P +RI A D L H YF P+ ++F
Sbjct: 667 PYNNLRKRFGAL--LSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSMFPT 724
Query: 504 LNYKYPPRRI 513
K +R+
Sbjct: 725 WPAKSEQQRV 734
>Hs10835055 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 795
Score = 174 bits (442), Expect = 3e-43
Identities = 101/310 (32%), Positives = 167/310 (53%), Gaps = 26/310 (8%)
Query: 206 QFYAIKKFKTEREGVEHYTGISQSACREMSLCRELDNNHLTKLVEIFLEKK--SIYMVSE 263
+ A+K+ K E+E G ++ RE++ + + ++ + EI + IY+V
Sbjct: 462 EIVALKRLKMEKEK----EGFPITSLREINTILKAQHPNIVTVREIVVGSNMDKIYIVMN 517
Query: 264 FAEHDLLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVD 323
+ EHDL ++ P P +K++M Q+L GV +LH NWILHRDLK +N++++
Sbjct: 518 YVEHDLKSLMETMKQP----FLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHA 573
Query: 324 GCVKIGDLGLARKFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAE 383
G +K+GD GLAR++ + ++ YT V+VT+WYRAPEL+LGA+ Y+ A+D+W+VGCIF E
Sbjct: 574 GILKVGDFGLAREYGSPLKA-YT--PVVVTLWYRAPELLLGAKEYSTAVDMWSVGCIFGE 630
Query: 384 LIGLRPIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPK 443
L+ +P+F G+ + +Q K+ + +G+P KIWP P ++
Sbjct: 631 LLTQKPLFPGKS-----------EIDQINKVFKDLGTPSEKIWPGYSELPAVKKMTFSEH 679
Query: 444 YRDNLTAWYQTAGGKDKTALDILYRLLQYDPIKRIDAIDALDHVYFTNGDPPVCENVFEG 503
+NL + D++ + L Y P +RI A D L H YF P+ ++F
Sbjct: 680 PYNNLRKRFGAL--LSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSMFPT 737
Query: 504 LNYKYPPRRI 513
K +R+
Sbjct: 738 WPAKSEQQRV 747
>Hs16357494 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 775
Score = 174 bits (440), Expect = 4e-43
Identities = 101/310 (32%), Positives = 166/310 (52%), Gaps = 26/310 (8%)
Query: 206 QFYAIKKFKTEREGVEHYTGISQSACREMSLCRELDNNHLTKLVEIFLEKK--SIYMVSE 263
+ A+K+ K E+E G ++ RE++ + + ++ + EI + IY+V
Sbjct: 442 EIVALKRLKMEKEN----EGFPITSLREINTILKAQHPNIVTVREIVVGSNMDKIYIVMN 497
Query: 264 FAEHDLLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVD 323
+ EHDL ++ P P +K++M Q+L GV +LH NWILHRDLK +N++++
Sbjct: 498 YVEHDLKSLMETMKQP----FLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHA 553
Query: 324 GCVKIGDLGLARKFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAE 383
G +K+GD GLAR++ + ++ YT V+VT WYRAPEL+LGA+ Y+ A+D+W+VGCIF E
Sbjct: 554 GILKVGDFGLAREYGSPLKA-YT--PVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGE 610
Query: 384 LIGLRPIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPK 443
L+ +P+F G + +Q K+ + +G+P KIWP P ++
Sbjct: 611 LLTQKPLFPGNS-----------EIDQINKVFKELGTPSEKIWPGYSELPVVKKMTFSEH 659
Query: 444 YRDNLTAWYQTAGGKDKTALDILYRLLQYDPIKRIDAIDALDHVYFTNGDPPVCENVFEG 503
+NL + + D++ + L Y P +RI A D L H YF P+ ++F
Sbjct: 660 PYNNLRKRFGAL--LSEQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSMFPT 717
Query: 504 LNYKYPPRRI 513
K +R+
Sbjct: 718 WPAKSEQQRV 727
>Hs16357492 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 777
Score = 174 bits (440), Expect = 4e-43
Identities = 101/310 (32%), Positives = 166/310 (52%), Gaps = 26/310 (8%)
Query: 206 QFYAIKKFKTEREGVEHYTGISQSACREMSLCRELDNNHLTKLVEIFLEKK--SIYMVSE 263
+ A+K+ K E+E G ++ RE++ + + ++ + EI + IY+V
Sbjct: 444 EIVALKRLKMEKEN----EGFPITSLREINTILKAQHPNIVTVREIVVGSNMDKIYIVMN 499
Query: 264 FAEHDLLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVD 323
+ EHDL ++ P P +K++M Q+L GV +LH NWILHRDLK +N++++
Sbjct: 500 YVEHDLKSLMETMKQP----FLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHA 555
Query: 324 GCVKIGDLGLARKFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAE 383
G +K+GD GLAR++ + ++ YT V+VT WYRAPEL+LGA+ Y+ A+D+W+VGCIF E
Sbjct: 556 GILKVGDFGLAREYGSPLKA-YT--PVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGE 612
Query: 384 LIGLRPIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPK 443
L+ +P+F G + +Q K+ + +G+P KIWP P ++
Sbjct: 613 LLTQKPLFPGNS-----------EIDQINKVFKELGTPSEKIWPGYSELPVVKKMTFSEH 661
Query: 444 YRDNLTAWYQTAGGKDKTALDILYRLLQYDPIKRIDAIDALDHVYFTNGDPPVCENVFEG 503
+NL + + D++ + L Y P +RI A D L H YF P+ ++F
Sbjct: 662 PYNNLRKRFGAL--LSEQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSMFPT 719
Query: 504 LNYKYPPRRI 513
K +R+
Sbjct: 720 WPAKSEQQRV 729
>Hs4502743 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 346
Score = 172 bits (437), Expect = 1e-42
Identities = 109/295 (36%), Positives = 159/295 (52%), Gaps = 26/295 (8%)
Query: 206 QFYAIKKFKTEREGVEHYTGISQSACREMSLCRELDNNHLTKLVEIFLEKKSIYMVSEFA 265
Q AIKK K E GI+++A RE+ L +EL + ++ L++ F K +I +V +F
Sbjct: 36 QIVAIKKIKLGHRS-EAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFM 94
Query: 266 EHDLLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGC 325
E DL II +S ++ P +K+ M L G+ YLHQ+WILHRDLKP N+++ +G
Sbjct: 95 ETDLEVIIKDNS----LVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGV 150
Query: 326 VKIGDLGLARKFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELI 385
+K+ D GLA+ F + YT +VT WYRAPEL+ GAR Y +D+WAVGCI AEL+
Sbjct: 151 LKLADFGLAKSFGS-PNRAYTHQ--VVTRWYRAPELLFGARMYGVGVDMWAVGCILAELL 207
Query: 386 GLRPIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPKYR 445
P G+ +Q +I E +G+P + WP++ S P+Y+ P
Sbjct: 208 LRVPFLPGDS-----------DLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGI- 255
Query: 446 DNLTAWYQTAGGKDKTALDILYRLLQYDPIKRIDAIDALDHVYFTN--GDPPVCE 498
L + AG LD++ L ++P RI A AL YF+N G P C+
Sbjct: 256 -PLHHIFSAAG---DDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQ 306
>Hs16357498 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 777
Score = 172 bits (436), Expect = 1e-42
Identities = 101/310 (32%), Positives = 165/310 (52%), Gaps = 26/310 (8%)
Query: 206 QFYAIKKFKTEREGVEHYTGISQSACREMSLCRELDNNHLTKLVEIFLEKK--SIYMVSE 263
+ A+K+ K E+E G ++ RE++ + + ++ + EI + IY+V
Sbjct: 444 EIVALKRLKMEKEK----EGFPITSLREINTILKAQHPNIVTVREIVVGSNMDKIYIVMN 499
Query: 264 FAEHDLLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVD 323
+ EHDL ++ P P +K++M Q+L GV +LH NWILHRDLK +N++++
Sbjct: 500 YVEHDLKSLMETMKQP----FLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHA 555
Query: 324 GCVKIGDLGLARKFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAE 383
G +K+GD GLAR++ + ++ YT V+VT WYRAPEL+LGA+ Y+ A+D+W+VGCIF E
Sbjct: 556 GILKVGDFGLAREYGSPLKA-YT--PVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGE 612
Query: 384 LIGLRPIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPK 443
L+ +P+F G + +Q K+ + +G+P KIWP P ++
Sbjct: 613 LLTQKPLFPGNS-----------EIDQINKVFKELGTPSEKIWPGYSELPVVKKMTFSEH 661
Query: 444 YRDNLTAWYQTAGGKDKTALDILYRLLQYDPIKRIDAIDALDHVYFTNGDPPVCENVFEG 503
+NL + D++ + L Y P +RI A D L H YF P+ ++F
Sbjct: 662 PYNNLRKRFGAL--LSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSMFPT 719
Query: 504 LNYKYPPRRI 513
K +R+
Sbjct: 720 WPAKSEQQRV 729
>Hs16357486 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 780
Score = 172 bits (436), Expect = 1e-42
Identities = 101/310 (32%), Positives = 165/310 (52%), Gaps = 26/310 (8%)
Query: 206 QFYAIKKFKTEREGVEHYTGISQSACREMSLCRELDNNHLTKLVEIFLEKK--SIYMVSE 263
+ A+K+ K E+E G ++ RE++ + + ++ + EI + IY+V
Sbjct: 447 EIVALKRLKMEKEK----EGFPITSLREINTILKAQHPNIVTVREIVVGSNMDKIYIVMN 502
Query: 264 FAEHDLLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVD 323
+ EHDL ++ P P +K++M Q+L GV +LH NWILHRDLK +N++++
Sbjct: 503 YVEHDLKSLMETMKQP----FLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHA 558
Query: 324 GCVKIGDLGLARKFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAE 383
G +K+GD GLAR++ + ++ YT V+VT WYRAPEL+LGA+ Y+ A+D+W+VGCIF E
Sbjct: 559 GILKVGDFGLAREYGSPLKA-YT--PVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGE 615
Query: 384 LIGLRPIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPK 443
L+ +P+F G + +Q K+ + +G+P KIWP P ++
Sbjct: 616 LLTQKPLFPGNS-----------EIDQINKVFKELGTPSEKIWPGYSELPVVKKMTFSEH 664
Query: 444 YRDNLTAWYQTAGGKDKTALDILYRLLQYDPIKRIDAIDALDHVYFTNGDPPVCENVFEG 503
+NL + D++ + L Y P +RI A D L H YF P+ ++F
Sbjct: 665 PYNNLRKRFGAL--LSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSMFPT 722
Query: 504 LNYKYPPRRI 513
K +R+
Sbjct: 723 WPAKSEQQRV 732
>Hs16357484 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 767
Score = 172 bits (436), Expect = 1e-42
Identities = 101/310 (32%), Positives = 165/310 (52%), Gaps = 26/310 (8%)
Query: 206 QFYAIKKFKTEREGVEHYTGISQSACREMSLCRELDNNHLTKLVEIFLEKK--SIYMVSE 263
+ A+K+ K E+E G ++ RE++ + + ++ + EI + IY+V
Sbjct: 434 EIVALKRLKMEKEK----EGFPITSLREINTILKAQHPNIVTVREIVVGSNMDKIYIVMN 489
Query: 264 FAEHDLLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVD 323
+ EHDL ++ P P +K++M Q+L GV +LH NWILHRDLK +N++++
Sbjct: 490 YVEHDLKSLMETMKQP----FLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHA 545
Query: 324 GCVKIGDLGLARKFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAE 383
G +K+GD GLAR++ + ++ YT V+VT WYRAPEL+LGA+ Y+ A+D+W+VGCIF E
Sbjct: 546 GILKVGDFGLAREYGSPLKA-YT--PVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGE 602
Query: 384 LIGLRPIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPK 443
L+ +P+F G + +Q K+ + +G+P KIWP P ++
Sbjct: 603 LLTQKPLFPGNS-----------EIDQINKVFKELGTPSEKIWPGYSELPVVKKMTFSEH 651
Query: 444 YRDNLTAWYQTAGGKDKTALDILYRLLQYDPIKRIDAIDALDHVYFTNGDPPVCENVFEG 503
+NL + D++ + L Y P +RI A D L H YF P+ ++F
Sbjct: 652 PYNNLRKRFGAL--LSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSMFPT 709
Query: 504 LNYKYPPRRI 513
K +R+
Sbjct: 710 WPAKSEQQRV 719
>Hs16357482 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 776
Score = 172 bits (436), Expect = 1e-42
Identities = 101/310 (32%), Positives = 165/310 (52%), Gaps = 26/310 (8%)
Query: 206 QFYAIKKFKTEREGVEHYTGISQSACREMSLCRELDNNHLTKLVEIFLEKK--SIYMVSE 263
+ A+K+ K E+E G ++ RE++ + + ++ + EI + IY+V
Sbjct: 443 EIVALKRLKMEKEK----EGFPITSLREINTILKAQHPNIVTVREIVVGSNMDKIYIVMN 498
Query: 264 FAEHDLLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVD 323
+ EHDL ++ P P +K++M Q+L GV +LH NWILHRDLK +N++++
Sbjct: 499 YVEHDLKSLMETMKQP----FLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHA 554
Query: 324 GCVKIGDLGLARKFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAE 383
G +K+GD GLAR++ + ++ YT V+VT WYRAPEL+LGA+ Y+ A+D+W+VGCIF E
Sbjct: 555 GILKVGDFGLAREYGSPLKA-YT--PVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGE 611
Query: 384 LIGLRPIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPK 443
L+ +P+F G + +Q K+ + +G+P KIWP P ++
Sbjct: 612 LLTQKPLFPGNS-----------EIDQINKVFKELGTPSEKIWPGYSELPVVKKMTFSEH 660
Query: 444 YRDNLTAWYQTAGGKDKTALDILYRLLQYDPIKRIDAIDALDHVYFTNGDPPVCENVFEG 503
+NL + D++ + L Y P +RI A D L H YF P+ ++F
Sbjct: 661 PYNNLRKRFGAL--LSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSMFPT 718
Query: 504 LNYKYPPRRI 513
K +R+
Sbjct: 719 WPAKSEQQRV 728
>Hs16357480 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 397
Score = 172 bits (436), Expect = 1e-42
Identities = 101/310 (32%), Positives = 165/310 (52%), Gaps = 26/310 (8%)
Query: 206 QFYAIKKFKTEREGVEHYTGISQSACREMSLCRELDNNHLTKLVEIFLEKK--SIYMVSE 263
+ A+K+ K E+E G ++ RE++ + + ++ + EI + IY+V
Sbjct: 64 EIVALKRLKMEKEK----EGFPITSLREINTILKAQHPNIVTVREIVVGSNMDKIYIVMN 119
Query: 264 FAEHDLLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVD 323
+ EHDL ++ P P +K++M Q+L GV +LH NWILHRDLK +N++++
Sbjct: 120 YVEHDLKSLMETMKQP----FLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHA 175
Query: 324 GCVKIGDLGLARKFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAE 383
G +K+GD GLAR++ + ++ YT V+VT WYRAPEL+LGA+ Y+ A+D+W+VGCIF E
Sbjct: 176 GILKVGDFGLAREYGSPLKA-YT--PVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGE 232
Query: 384 LIGLRPIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPK 443
L+ +P+F G + +Q K+ + +G+P KIWP P ++
Sbjct: 233 LLTQKPLFPGNS-----------EIDQINKVFKELGTPSEKIWPGYSELPVVKKMTFSEH 281
Query: 444 YRDNLTAWYQTAGGKDKTALDILYRLLQYDPIKRIDAIDALDHVYFTNGDPPVCENVFEG 503
+NL + D++ + L Y P +RI A D L H YF P+ ++F
Sbjct: 282 PYNNLRKRFGAL--LSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSMFPT 339
Query: 504 LNYKYPPRRI 513
K +R+
Sbjct: 340 WPAKSEQQRV 349
>SPBC11B10.09 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 297
Score = 172 bits (435), Expect = 2e-42
Identities = 94/284 (33%), Positives = 164/284 (57%), Gaps = 26/284 (9%)
Query: 209 AIKKFKTEREGVEHYTGISQSACREMSLCRELDN----NHLTKLVEIFLEKKSIYMVSEF 264
A+KK + E E G+ +A RE+SL +E+++ ++ +L++I + +Y+V EF
Sbjct: 31 AMKKIRLEDES----EGVPSTAIREISLLKEVNDENNRSNCVRLLDILHAESKLYLVFEF 86
Query: 265 AEHDLLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDG 324
+ DL + + S + PR+++ +Q+++GV++ H I+HRDLKP N+++ +G
Sbjct: 87 LDMDLKKYMDRISETGATSLDPRLVQKFTYQLVNGVNFCHSRRIIHRDLKPQNLLIDKEG 146
Query: 325 CVKIGDLGLARKFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAEL 384
+K+ D GLAR F ++ YT + IVT+WYRAPE++LG+RHY+ +D+W+VGCIFAE+
Sbjct: 147 NLKLADFGLARSFGVPLRN-YTHE--IVTLWYRAPEVLLGSRHYSTGVDIWSVGCIFAEM 203
Query: 385 IGLRPIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPKY 444
I P+F G+ + ++ KI +V+G+P+ ++WP + +Y K
Sbjct: 204 IRRSPLFPGDS-----------EIDEIFKIFQVLGTPNEEVWPGVTLLQDYKSTFPRWKR 252
Query: 445 RDNLTAWYQTAGGKDKTALDILYRLLQYDPIKRIDAIDALDHVY 488
D ++ ++ A+++L +L YDP RI A AL Y
Sbjct: 253 MD----LHKVVPNGEEDAIELLSAMLVYDPAHRISAKRALQQNY 292
>Hs4502747 [D] KOG0669 Cyclin T-dependent kinase CDK9
Length = 372
Score = 172 bits (435), Expect = 2e-42
Identities = 117/330 (35%), Positives = 174/330 (52%), Gaps = 51/330 (15%)
Query: 206 QFYAIKKFKTEREGVEHYTGISQSACREMSLCRELDNNHLTKLVEIFLEKKS-------- 257
Q A+KK E E G +A RE+ + + L + ++ L+EI K S
Sbjct: 43 QKVALKKVLMENEK----EGFPITALREIKILQLLKHENVVNLIEICRTKASPYNRCKGS 98
Query: 258 IYMVSEFAEHDLLQIIHFHSHPEKRLIPPRM--LKSIMWQILDGVSYLHQNWILHRDLKP 315
IY+V +F EHDL ++ L+ + +K +M +L+G+ Y+H+N ILHRD+K
Sbjct: 99 IYLVFDFCEHDLAGLL------SNVLVKFTLSEIKRVMQMLLNGLYYIHRNKILHRDMKA 152
Query: 316 ANIMVTVDGCVKIGDLGLARKFN---NMVQTLYTGDKVIVTIWYRAPELILGARHYTPAI 372
AN+++T DG +K+ D GLAR F+ N YT +VT+WYR PEL+LG R Y P I
Sbjct: 153 ANVLITRDGVLKLADFGLARAFSLAKNSQPNRYTNR--VVTLWYRPPELLLGERDYGPPI 210
Query: 373 DLWAVGCIFAELIGLRPIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHKIWPNIDSY 432
DLW GCI AE+ PI +G + +Q I ++ GS ++WPN+D+Y
Sbjct: 211 DLWGAGCIMAEMWTRSPIMQGNT-----------EQHQLALISQLCGSITPEVWPNVDNY 259
Query: 433 PEY--LQLAK--MPKYRDNLTAWYQTAGGKDKTALDILYRLLQYDPIKRIDAIDALDHVY 488
Y L+L K K +D L A+ +D ALD++ +LL DP +RID+ DAL+H +
Sbjct: 260 ELYEKLELVKGQKRKVKDRLKAYV-----RDPYALDLIDKLLVLDPAQRIDSDDALNHDF 314
Query: 489 FTNGDPP------VCENVFEGLNYKYPPRR 512
F + P + ++ Y PPRR
Sbjct: 315 FWSDPMPSDLKGMLSTHLTSMFEYLAPPRR 344
>At1g18040 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 391
Score = 171 bits (433), Expect = 3e-42
Identities = 107/351 (30%), Positives = 167/351 (47%), Gaps = 47/351 (13%)
Query: 206 QFYAIKKFKTEREGVEHYTGISQSACREMSLCRELDNNHLTKLVEIFLEKKSIYMVSEFA 265
Q AIKK + ++ G++ +A RE+ + +EL + H+ L++ F K+++++V EF
Sbjct: 36 QTVAIKKIRLGKQR----EGVNITALREIKMLKELKHPHIILLIDAFPHKENLHLVFEFM 91
Query: 266 EHDLLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGC 325
E DL +I + P +KS + G++Y H W+LHRD+KP N+++ VDG
Sbjct: 92 ETDLEAVIR----DSNIFLSPADIKSYLLMTFKGLAYCHDKWVLHRDMKPNNLLIGVDGQ 147
Query: 326 VKIGDLGLARKFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELI 385
+K+ D GLAR F + + + WYRAPEL+ GA+ Y A+D+WAV CIFAEL+
Sbjct: 148 LKLADFGLARIFGSPNRKF---THQVFARWYRAPELLFGAKQYGAAVDVWAVACIFAELL 204
Query: 386 GLRPIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEYL--QLAKMPK 443
RP +G +Q KI G+P WP++ P+Y+ Q P
Sbjct: 205 LRRPFLQGNS-----------DIDQLSKIFAAFGTPKADQWPDLTKLPDYVEYQFVPAPS 253
Query: 444 YRDNLTAWYQTAGGKDKTALDILYRLLQYDPIKRIDAIDALDHVYFTNGDPPV------- 496
R A ALD+L ++ YDP RI AL+H YFT+ P
Sbjct: 254 LRSLFPA-------VSDDALDLLSKMFTYDPKARISIKQALEHRYFTSAPAPTDPAKLPK 306
Query: 497 ---------CENVFEGLNYKYPPRRIHTNDNDITNVGNDNNQANHSQKQPM 538
E + + PPR++ + V + + + Q+ PM
Sbjct: 307 PVPKQDGKSSYGKHEAITVQSPPRKLRRVMPERGRVDSLKSHVDKDQQAPM 357
>At5g10270 [D] KOG0600 Cdc2-related protein kinase
Length = 505
Score = 170 bits (431), Expect = 5e-42
Identities = 105/311 (33%), Positives = 165/311 (52%), Gaps = 45/311 (14%)
Query: 206 QFYAIKKFKTEREGVEHYTGISQSACREMSLCRELDNNHLTKLVEIFLE----------- 254
+ A+KK + + E G +A RE+ + ++L + ++ +L EI
Sbjct: 50 EIVALKKIRMDNER----EGFPITAIREIKILKKLHHENVIQLKEIVTSPGRDRDDQGKP 105
Query: 255 -----KKSIYMVSEFAEHDLLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWIL 309
K IYMV E+ +HDL + P R P+ +K M Q+L G+ Y H N +L
Sbjct: 106 DNNKYKGGIYMVFEYMDHDLTGLA---DRPGLRFTVPQ-IKCYMKQLLTGLHYCHVNQVL 161
Query: 310 HRDLKPANIMVTVDGCVKIGDLGLARKFNNMVQTLYTGDKV--IVTIWYRAPELILGARH 367
HRD+K +N+++ +G +K+ D GLAR +++ +TG+ ++T+WYR PEL+LGA
Sbjct: 162 HRDIKGSNLLIDNEGNLKLADFGLARSYSHD----HTGNLTNRVITLWYRPPELLLGATK 217
Query: 368 YTPAIDLWAVGCIFAELIGLRPIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHKIWP 427
Y PAID+W+VGCIFAEL+ +PI G+ + Q KI E+ GSPD K+WP
Sbjct: 218 YGPAIDMWSVGCIFAELLHAKPILPGKN-----------EQEQLNKIFELCGSPDEKLWP 266
Query: 428 NIDSYPEYLQLAKMPKYRDNLTAWYQTAGGKDKTALDILYRLLQYDPIKRIDAIDALDHV 487
+ P + + + +++ D+ AL++L ++L DP +RI A DALD
Sbjct: 267 GVSKMPWFNNFKPARPLKRRVREFFRHF---DRHALELLEKMLVLDPAQRISAKDALDAE 323
Query: 488 YFTNGDPPVCE 498
YF DP C+
Sbjct: 324 YFWT-DPLPCD 333
>7290565 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 353
Score = 170 bits (431), Expect = 5e-42
Identities = 104/292 (35%), Positives = 156/292 (52%), Gaps = 28/292 (9%)
Query: 206 QFYAIKKFKT-EREGVEHYTGISQSACREMSLCRELDNNHLTKLVEIFLEKKSIYMVSEF 264
Q A+KK K RE GI+++A RE+ + +EL + ++ LV++F + ++ +V +F
Sbjct: 36 QIVAVKKIKKGSREDARD--GINRTALREIKILQELQHENIIGLVDVFGQLSNVSLVFDF 93
Query: 265 AEHDLLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDG 324
+ DL II K ++ +K+ L G+ YLH NWILHRDLKP N++V DG
Sbjct: 94 MDTDLEVIIK----DNKIILTQANIKAYAIMTLKGLEYLHLNWILHRDLKPNNLLVNSDG 149
Query: 325 CVKIGDLGLARKFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAEL 384
+KIGD GLA+ F + +YT +VT WYR+PEL+ GAR Y +D+WAVGCI AEL
Sbjct: 150 ILKIGDFGLAKSFGS-PNRIYTHH--VVTRWYRSPELLFGARQYGTGVDMWAVGCILAEL 206
Query: 385 IGLRPIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMP-K 443
+ P G+ +Q +I +G+P WP++ +YLQ P
Sbjct: 207 MLRVPFMPGDS-----------DLDQLTRIFSTLGTPTEAEWPHLSKLHDYLQFRNFPGT 255
Query: 444 YRDNLTAWYQTAGGKDKTALDILYRLLQYDPIKRIDAIDALDHVYFTNGDPP 495
DN+ TA G D + ++ RL +P++R+ +AL YF N P
Sbjct: 256 PLDNIF----TAAGND--LIHLMQRLFAMNPLRRVSCREALSMPYFANKPAP 301
>At1g73690 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 398
Score = 170 bits (430), Expect = 6e-42
Identities = 99/287 (34%), Positives = 153/287 (52%), Gaps = 27/287 (9%)
Query: 209 AIKKFKTEREGVEHYTGISQSACREMSLCRELDNNHLTKLVEIFLEKKSIYMVSEFAEHD 268
AIKK + +E G++ +A RE+ L +EL + H+ +L++ F K+++++V EF E D
Sbjct: 38 AIKKIRLGKEK----EGVNVTALREIKLLKELKHPHIIELIDAFPHKENLHIVFEFMETD 93
Query: 269 LLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGCVKI 328
L +I + P +KS + IL G+ Y H W+LHRD+KP N+++ +G +K+
Sbjct: 94 LEAVIR----DRNLYLSPGDVKSYLQMILKGLEYCHGKWVLHRDMKPNNLLIGPNGQLKL 149
Query: 329 GDLGLARKFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELIGLR 388
D GLAR F + + + WYRAPEL+ GA+ Y A+D+WA GCIFAEL+ R
Sbjct: 150 ADFGLARIFGSPGRKF---THQVFARWYRAPELLFGAKQYDGAVDVWAAGCIFAELLLRR 206
Query: 389 PIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPKYRDNL 448
P +G +Q KI G+P WP++ P+Y++ +P +L
Sbjct: 207 PFLQGNS-----------DIDQLSKIFAAFGTPKADQWPDMICLPDYVEYQFVP--APSL 253
Query: 449 TAWYQTAGGKDKTALDILYRLLQYDPIKRIDAIDALDHVYFTNGDPP 495
+ T + ALD+L ++ YDP RI AL H YFT+ P
Sbjct: 254 RSLLPTV---SEDALDLLSKMFTYDPKSRISIQQALKHRYFTSAPSP 297
>CE01761 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 719
Score = 167 bits (424), Expect = 3e-41
Identities = 109/328 (33%), Positives = 168/328 (50%), Gaps = 30/328 (9%)
Query: 206 QFYAIKKFKTEREGVEHYTGISQSACREMSLCRELDNN-HLTKLVEIFLEKK--SIYMVS 262
+ A+K+ K E+E G +A RE+++ + N+ ++ + EI L IYM
Sbjct: 380 EIVALKRLKMEKEK----EGFPITALREINMLLKAGNHPNIVNVKEILLGSNMDKIYMAM 435
Query: 263 EFAEHDLLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTV 322
EF EHD+ ++ S KR K+++ Q+L G+ ++H+ WILHRDLK +N++++
Sbjct: 436 EFVEHDMKSLLDTMSRRNKRFSIGEQ-KTLLQQLLSGIEHMHKLWILHRDLKTSNLLMSH 494
Query: 323 DGCVKIGDLGLARKFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFA 382
G +KI D GLAR++ + ++ + ++VT+WYR+PEL+LG R Y+ +D+W+VGCI A
Sbjct: 495 KGILKIADFGLAREYGDPLKKFTS---IVVTLWYRSPELLLGTRLYSTPVDMWSVGCIMA 551
Query: 383 ELIGLRPIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMP 442
E I L+P+F G + Q +KI MG+P IWP + + L
Sbjct: 552 EFILLKPLFPGRG-----------ELEQIKKIFMEMGTPTESIWPGVTELDGWKALT-FE 599
Query: 443 KYRDNLTAWYQTAGG-KDKTALDILYRLLQYDPIKRIDAIDALDHVYFTNGDPPVCENVF 501
KY N AG + T +L LL DP R A ALDH +FT PV F
Sbjct: 600 KYPYNQLRKRFLAGRLLNDTGFKLLNGLLTLDPKNRFSATQALDHEWFTEEPYPVPPEEF 659
Query: 502 EGL------NYKYPPRRIHTNDNDITNV 523
N PP + +N I++V
Sbjct: 660 PTFPAKSEQNKAPPPAKQKQQENRISHV 687
>YPL031c [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 305
Score = 167 bits (423), Expect = 4e-41
Identities = 93/285 (32%), Positives = 156/285 (54%), Gaps = 21/285 (7%)
Query: 207 FYAIKKFKTEREGVEHYTGISQSACREMSLCRELDNNHLTKLVEIFLEKKSIYMVSEFAE 266
+ A+K+ K + E G +A RE+SL +EL + ++ +L ++ + + +V EF +
Sbjct: 32 YVALKEVKLDSE-----EGTPSTAIREISLMKELKHENIVRLYDVIHTENKLTLVFEFMD 86
Query: 267 HDLLQIIHFHSHPEK-RLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGC 325
+DL + + + R + ++K WQ+L G+++ H+N ILHRDLKP N+++ G
Sbjct: 87 NDLKKYMDSRTVGNTPRGLELNLVKYFQWQLLQGLAFCHENKILHRDLKPQNLLINKRGQ 146
Query: 326 VKIGDLGLARKFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELI 385
+K+GD GLAR F V T +VT+WYRAP++++G+R Y+ +ID+W+ GCI AE+I
Sbjct: 147 LKLGDFGLARAFGIPVNTF---SSEVVTLWYRAPDVLMGSRTYSTSIDIWSCGCILAEMI 203
Query: 386 GLRPIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPKYR 445
+P+F G Q + I ++MG+P+ +WP++ P+Y + R
Sbjct: 204 TGKPLFPGTN-----------DEEQLKLIFDIMGTPNESLWPSVTKLPKYNPNIQQRPPR 252
Query: 446 D-NLTAWYQTAGGKDKTALDILYRLLQYDPIKRIDAIDALDHVYF 489
D T D +D L+ LLQ +P R+ A AL H +F
Sbjct: 253 DLRQVLQPHTKEPLDGNLMDFLHGLLQLNPDMRLSAKQALHHPWF 297
>At5g64960 [D] KOG0600 Cdc2-related protein kinase
Length = 513
Score = 167 bits (423), Expect = 4e-41
Identities = 107/311 (34%), Positives = 163/311 (52%), Gaps = 45/311 (14%)
Query: 206 QFYAIKKFKTEREGVEHYTGISQSACREMSLCRELDNNHLTKLVEIFLE----------- 254
+ A+KK + + E G +A RE+ + ++L + ++ L EI
Sbjct: 50 EIVALKKIRMDNER----EGFPITAIREIKILKKLHHENVIHLKEIVTSPGRDRDDQGKP 105
Query: 255 -----KKSIYMVSEFAEHDLLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWIL 309
K IYMV E+ +HDL + P R P+ +K M Q+L G+ Y H N +L
Sbjct: 106 DNNKYKGGIYMVFEYMDHDLTGLA---DRPGLRFTVPQ-IKCYMKQLLTGLHYCHVNQVL 161
Query: 310 HRDLKPANIMVTVDGCVKIGDLGLARKFNNMVQTLYTGDKV--IVTIWYRAPELILGARH 367
HRD+K +N+++ +G +K+ D GLAR +++ +TG+ ++T+WYR PEL+LGA
Sbjct: 162 HRDIKGSNLLIDNEGNLKLADFGLARSYSHD----HTGNLTNRVITLWYRPPELLLGATK 217
Query: 368 YTPAIDLWAVGCIFAELIGLRPIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHKIWP 427
Y PAID+W+VGCIFAEL+ +PI G+ + Q KI E+ GSPD WP
Sbjct: 218 YGPAIDMWSVGCIFAELLNGKPILPGKT-----------ENEQLNKIYELCGSPDESNWP 266
Query: 428 NIDSYPEYLQLAKMPKYRDNLTAWYQTAGGKDKTALDILYRLLQYDPIKRIDAIDALDHV 487
+ P Y Q+ + + Y+ D+ AL++L ++L DP +RI A DALD
Sbjct: 267 GVSKMPWYNQMKSSRPLKRRVREIYRHF---DRHALELLEKMLVLDPSQRICAKDALDAE 323
Query: 488 YFTNGDPPVCE 498
YF DP C+
Sbjct: 324 YFWT-DPLPCD 333
>ECU02g1450 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 308
Score = 167 bits (422), Expect = 5e-41
Identities = 98/288 (34%), Positives = 153/288 (53%), Gaps = 32/288 (11%)
Query: 209 AIKKFKTEREGVEHYT-GISQSACREMSLCRELDNNHLTKLVEIFLEKKSIYMVSEFAEH 267
AIKK K + YT G SA RE+ + +D+ ++ +L++ F+ K +++V E+ E
Sbjct: 44 AIKKIKPTK-----YTQGHEISAIREIKSLKRIDSKYVVRLIDTFVYDKCVHIVLEYVET 98
Query: 268 DLLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGCVK 327
+L +I ++I P +K+ + +L GV H+ +I+HRD+KP NI++T +G VK
Sbjct: 99 NLENVIR----NSDKIIMPGDIKAWILMVLRGVYECHRLFIIHRDIKPNNILITSEGMVK 154
Query: 328 IGDLGLARKFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELIGL 387
+ D GL R N + VT WYRAPEL++G+R Y +D+W+VGC+FAEL
Sbjct: 155 LADFGLTRGIGNRMTPQ------AVTRWYRAPELLMGSRDYGSPVDMWSVGCVFAELFLR 208
Query: 388 RPIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPKYRDN 447
P+F G+ Q I +G+P + WP + + PE+L + PK +
Sbjct: 209 VPLFAGDT-----------DIQQLDMIFRALGTPVEREWPGVSTLPEFLDFQQYPK--AS 255
Query: 448 LTAWYQTAGGKDKTALDILYRLLQYDPIKRIDAIDALDHVYFTNGDPP 495
L + A ALD+L +LL +P RI DA+ H YF + PP
Sbjct: 256 LNGLFSAA---SSDALDLLEKLLTLNPCNRISCDDAIKHPYFKSSPPP 300
>At1g67580 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 752
Score = 166 bits (421), Expect = 7e-41
Identities = 100/292 (34%), Positives = 159/292 (54%), Gaps = 32/292 (10%)
Query: 206 QFYAIKKFKTEREGVEHYTGISQSACREMSLCRELDNNHLTKLVEIFLEKK--SIYMVSE 263
+ A+KK K E+E G ++ RE+++ + + + E+ + SI+MV E
Sbjct: 430 EIVALKKVKMEKER----EGFPLTSLREINILLSFHHPSIVDVKEVVVGSSLDSIFMVME 485
Query: 264 FAEHDLLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVD 323
+ EHDL ++ K+ +K +M Q+L+GV YLH NW+LHRDLK +N+++
Sbjct: 486 YMEHDLKALME----TMKQRFSQSEVKCLMLQLLEGVKYLHDNWVLHRDLKTSNLLLNNR 541
Query: 324 GCVKIGDLGLARKFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAE 383
G +KI D GLAR++ + ++ YT ++VT+WYRAPEL+LGA+ Y+ AID+W++GCI AE
Sbjct: 542 GELKICDFGLARQYGSPLKP-YT--HLVVTLWYRAPELLLGAKQYSTAIDMWSLGCIMAE 598
Query: 384 LIGLRPIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPK 443
L+ P+F G+ + +Q KI ++G+P+ IWP P K
Sbjct: 599 LLMKAPLFNGKT-----------EFDQLDKIFRILGTPNESIWPGFSKLPGV--KVNFVK 645
Query: 444 YRDNL------TAWYQTAGGKDKTALDILYRLLQYDPIKRIDAIDALDHVYF 489
++ NL + A D+L +LL YDP +RI +AL H +F
Sbjct: 646 HQYNLLRKKFPATSFTGAPVLSDAGFDLLNKLLTYDPERRITVNEALKHDWF 697
>SPCC16C4.11 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 288
Score = 165 bits (417), Expect = 2e-40
Identities = 92/265 (34%), Positives = 146/265 (54%), Gaps = 20/265 (7%)
Query: 225 GISQSACREMSLCRELDNNHLTKLVEIFLEKKSIYMVSEFAEHDLLQIIHFHSHPEKRLI 284
G +A RE+SL +EL + ++ L ++ + + +V E+ E DL + + ++ + +
Sbjct: 41 GTPSTAIREISLMKELRHPNIMSLSDVLQTENKLMLVFEYMEKDLKK--YMDTYGNQGAL 98
Query: 285 PPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGCVKIGDLGLARKFNNMVQTL 344
PP +K+ Q+L G+S+ H+N +LHRDLKP N+++ G +K+ D GLAR V T
Sbjct: 99 PPSQVKNFTQQLLKGISFCHENRVLHRDLKPQNLLINSRGELKLADFGLARSIGIPVNTF 158
Query: 345 YTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELIGLRPIFKGEEAKMESKKSV 404
+VT+WYRAP+++LG+R Y+ +ID+W+VGCI AE+ RP+F G
Sbjct: 159 ---SNEVVTLWYRAPDVLLGSRVYSTSIDIWSVGCIMAEMATGRPLFAGSN--------- 206
Query: 405 LFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPKYRDNLTAWYQTAGGKDKTALD 464
+Q KI ++G+P + WP I PEY + K +D L + T D LD
Sbjct: 207 --NEDQLLKIFRLLGTPTEQSWPGISLLPEYKPTFPIYKAQD-LAYLFPTF---DPLGLD 260
Query: 465 ILYRLLQYDPIKRIDAIDALDHVYF 489
+L R+L+ P R DAL H +F
Sbjct: 261 LLRRMLRLQPELRTTGQDALQHAWF 285
>Hs4826675 [UT] KOG0662 Cyclin-dependent kinase CDK5
Length = 292
Score = 164 bits (415), Expect = 4e-40
Identities = 91/272 (33%), Positives = 155/272 (56%), Gaps = 23/272 (8%)
Query: 225 GISQSACREMSLCRELDNNHLTKLVEIFLEKKSIYMVSEFAEHDLLQIIHFHSHPEKRLI 284
G+ SA RE+ L +EL + ++ +L ++ K + +V EF + DL + +F S +
Sbjct: 43 GVPSSALREICLLKELKHKNIVRLHDVLHSDKKLTLVFEFCDQDLKK--YFDSCNGD--L 98
Query: 285 PPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGCVKIGDLGLARKFNNMVQTL 344
P ++KS ++Q+L G+ + H +LHRDLKP N+++ +G +K+ D GLAR F V+
Sbjct: 99 DPEIVKSFLFQLLKGLGFCHSRNVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVR-C 157
Query: 345 YTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELIGL-RPIFKGEEAKMESKKS 403
Y+ + +VT+WYR P+++ GA+ Y+ +ID+W+ GCIFAEL RP+F G +
Sbjct: 158 YSAE--VVTLWYRPPDVLFGAKLYSTSIDMWSAGCIFAELANAGRPLFPGNDVD------ 209
Query: 404 VLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPKYRDNLTAWYQTAGGKDKTAL 463
+Q ++I ++G+P + WP++ P+Y P T+ + T
Sbjct: 210 -----DQLKRIFRLLGTPTEEQWPSMTKLPDYKPYPMYPA----TTSLVNVVPKLNATGR 260
Query: 464 DILYRLLQYDPIKRIDAIDALDHVYFTNGDPP 495
D+L LL+ +P++RI A +AL H YF++ PP
Sbjct: 261 DLLQNLLKCNPVQRISAEEALQHPYFSDFCPP 292
>SPBC18H10.15 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 398
Score = 164 bits (414), Expect = 5e-40
Identities = 98/291 (33%), Positives = 160/291 (54%), Gaps = 30/291 (10%)
Query: 209 AIKKFKTEREGVEHYTGISQSACREMSLCRELDNNHLTKLVEIFLEK--KSIYMVSEFAE 266
A+KK K + G+ G ++ RE+ + ++++ +L ++ + K K +Y+V EF E
Sbjct: 101 ALKKIKFDPNGI----GFPITSLREIESLSSIRHDNIVELEKVVVGKDLKDVYLVMEFME 156
Query: 267 HDLLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGCV 326
HDL ++ + PE L +K++M Q+L +++H +W LHRDLKP+N+++ G +
Sbjct: 157 HDLKTLLD--NMPEDFL--QSEVKTLMLQLLAATAFMHHHWYLHRDLKPSNLLMNNTGEI 212
Query: 327 KIGDLGLARKFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELIG 386
K+ D GLAR + +L +++VT+WYRAPEL+LGA Y ID+W++GCIFAE+I
Sbjct: 213 KLADFGLARPVSEPKSSL---TRLVVTLWYRAPELLLGAPSYGKEIDMWSIGCIFAEMIT 269
Query: 387 LRPIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHKIWPN--IDSYPEYLQLAKMPKY 444
P+F G+ + +Q KI ++G P + WP + Y ++ +P +
Sbjct: 270 RTPLFSGKS-----------ELDQLYKIFNLLGYPTREEWPQYFLLPYANKIKHPTVPTH 318
Query: 445 RDNLTAWYQTAGGKDKTALDILYRLLQYDPIKRIDAIDALDHVYFTNGDPP 495
T+ G A D+L RLL +P KRI A +AL+H YF P
Sbjct: 319 SKIRTSIPNLTG----NAYDLLNRLLSLNPAKRISAKEALEHPYFYESPRP 365
>Hs4502731 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 360
Score = 162 bits (409), Expect = 2e-39
Identities = 103/298 (34%), Positives = 157/298 (52%), Gaps = 34/298 (11%)
Query: 206 QFYAIKKFKTEREGVEHYTGISQSACREMSLCRELDNNHLTKLVEIFLEK--KSIYMVSE 263
+ A+KK + ++E GI S+ RE++L L + ++ +L E+ + +SI++V
Sbjct: 63 EIVALKKVRMDKEK----DGIPISSLREITLLLRLRHPNIVELKEVVVGNHLESIFLVMG 118
Query: 264 FAEHDLLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVD 323
+ E DL ++ P +K I+ Q+L G+ YLH+N+I+HRDLK +N+++T
Sbjct: 119 YCEQDLASLLENMPTP----FSEAQVKCIVLQVLRGLQYLHRNFIIHRDLKVSNLLMTDK 174
Query: 324 GCVKIGDLGLARKFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAE 383
GCVK D GLAR + V+ + +VT+WYRAPEL+LG T +ID+WAVGCI AE
Sbjct: 175 GCVKTADFGLARAYGVPVKPM---TPKVVTLWYRAPELLLGTTTQTTSIDMWAVGCILAE 231
Query: 384 LIGLRPIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPK 443
L+ RP+ G + +Q I++++G+P IWP P Q + +
Sbjct: 232 LLAHRPLLPGTS-----------EIHQIDLIVQLLGTPSENIWPGFSKLPLVGQYSLRKQ 280
Query: 444 YRDNLT---AWYQTAGGKDKTALDILYRLLQYDPIKRIDAIDALDHVYFTNGDPPVCE 498
+NL W AG L +L+ L YDP KR A D L+ YF P CE
Sbjct: 281 PYNNLKHKFPWLSEAG------LRLLHFLFMYDPKKRATAGDCLESSYFKE-KPLPCE 331
>At1g66750 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 348
Score = 161 bits (408), Expect = 2e-39
Identities = 90/271 (33%), Positives = 145/271 (53%), Gaps = 23/271 (8%)
Query: 225 GISQSACREMSLCRELDNNHLTKLVEIFLEKKSIYMVSEFAEHDLLQIIHFHSHPEKRLI 284
G++ +A RE+ L +EL++ H+ +L++ F S+++V E+ + DL +I +
Sbjct: 52 GVNFTALREIKLLKELNHPHIVELIDAFPHDGSLHLVFEYMQTDLEAVIR----DRNIFL 107
Query: 285 PPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGCVKIGDLGLARKFNNMVQTL 344
P +KS M L G++Y H+ W+LHRD+KP N+++ +G +K+ D GLAR F + +
Sbjct: 108 SPGDIKSYMLMTLKGLAYCHKKWVLHRDMKPNNLLIGENGLLKLADFGLARLFGSPNRRF 167
Query: 345 YTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELIGLRPIFKGEEAKMESKKSV 404
+ WYRAPEL+ G+R Y +D+WA GCIFAEL+ RP G
Sbjct: 168 ---THQVFATWYRAPELLFGSRQYGAGVDVWAAGCIFAELLLRRPFLPGST--------- 215
Query: 405 LFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPKYRDNLTAWYQTAGGKDKTALD 464
+ +Q KI + G+P W ++ P+Y++ + P L + A ALD
Sbjct: 216 --EIDQLGKIFQAFGTPVPSQWSDMIYLPDYMEFSYTP--APPLRTIFPMA---SDDALD 268
Query: 465 ILYRLLQYDPIKRIDAIDALDHVYFTNGDPP 495
+L ++ YDP +RI ALDH YF++ P
Sbjct: 269 LLAKMFIYDPRQRITIQQALDHRYFSSSPSP 299
>Hs16950647 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 314
Score = 161 bits (407), Expect = 3e-39
Identities = 100/289 (34%), Positives = 154/289 (52%), Gaps = 33/289 (11%)
Query: 206 QFYAIKKFKTEREGVEHYTGISQSACREMSLCRELDNNHLTKLVEIFLEK--KSIYMVSE 263
+ A+KK + ++E GI S+ RE++L L + ++ +L E+ + +SI++V
Sbjct: 34 EIVALKKVRMDKEK----DGIPISSLREITLLLRLRHPNIVELKEVVVGNHLESIFLVMG 89
Query: 264 FAEHDLLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVD 323
+ E DL ++ P +K I+ Q+L G+ YLH+N+I+HRDLK +N+++T
Sbjct: 90 YCEQDLASLLENMPTP----FSEAQVKCIVLQVLRGLQYLHRNFIIHRDLKVSNLLMTDK 145
Query: 324 GCVKIGDLGLARKFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAE 383
GCVK D GLAR + V+ + +VT+WYRAPEL+LG T +ID+WAVGCI AE
Sbjct: 146 GCVKTADFGLARAYGVPVKPM---TPKVVTLWYRAPELLLGTTTQTTSIDMWAVGCILAE 202
Query: 384 LIGLRPIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPK 443
L+ RP+ G + +Q I++++G+P IWP P Q + +
Sbjct: 203 LLAHRPLLPGTS-----------EIHQIDLIVQLLGTPSENIWPGFSKLPLVGQYSLRKQ 251
Query: 444 YRDNLT---AWYQTAGGKDKTALDILYRLLQYDPIKRIDAIDALDHVYF 489
+NL W AG L +L+ L YDP KR A D L+ YF
Sbjct: 252 PYNNLKHKFPWLSEAG------LRLLHFLFMYDPKKRATAGDCLESSYF 294
>SPBC19F8.07 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 335
Score = 160 bits (406), Expect = 4e-39
Identities = 92/283 (32%), Positives = 154/283 (53%), Gaps = 28/283 (9%)
Query: 209 AIKKFKTEREGVEHYTGISQSACREMSLCRELDNNHLTKLVEIFLEKKSIYMVSEFAEHD 268
AIKK K + GI SA RE+ RE ++++ +LV++F K ++ ++ EF + D
Sbjct: 38 AIKKIKVG----QFKDGIDISALREIKFLRESRHDNVIELVDVFSTKSNLNIILEFLDSD 93
Query: 269 LLQIIHFHSHPEKRLI-PPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGCVK 327
L +I +K ++ P +KS M +L G+ ++H +ILHRDLKP N++++ DG +K
Sbjct: 94 LEMLIK-----DKFIVFQPAHIKSWMVMLLRGLHHIHSRFILHRDLKPNNLLISSDGVLK 148
Query: 328 IGDLGLARKFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELIGL 387
+ D GL+R F + ++T WYR PEL +G R Y +D+W+VGCIFAEL+
Sbjct: 149 LADFGLSRDFGTPSHMSHQ----VITRWYRPPELFMGCRSYGTGVDMWSVGCIFAELMLR 204
Query: 388 RPIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPKYRDN 447
P GE +Q I +G+P+ ++ ++ P Y+++ +P
Sbjct: 205 TPYLPGES-----------DLDQLNVIFRALGTPEPEVIKSMQQLPNYVEMKHIPPPNGG 253
Query: 448 LTAWYQTAGGKDKTALDILYRLLQYDPIKRIDAIDALDHVYFT 490
+ A + AG ++ +D+L +L Y+P +R A AL+H YF+
Sbjct: 254 MEALFSAAGHEE---IDLLKMMLDYNPYRRPTAQQALEHHYFS 293
>7303051 [UT] KOG0662 Cyclin-dependent kinase CDK5
Length = 294
Score = 160 bits (406), Expect = 4e-39
Identities = 93/288 (32%), Positives = 159/288 (54%), Gaps = 27/288 (9%)
Query: 205 IQFYAIKKFKTEREGVEHYTGISQSACREMSLCRELDNNHLTKLVEIFLEKKSIYMVSEF 264
++ A+K+ + + + G+ SA RE+ L +EL + ++ +L+++ K + +V E
Sbjct: 27 MEIVALKRVRLDEDD----EGVPSSALREICLLKELKHKNIVRLIDVLHSDKKLTLVFEH 82
Query: 265 AEHDLLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDG 324
+ DL + +F S + I + +S M Q+L G+++ H + +LHRDLKP N+++ +G
Sbjct: 83 CDQDLKK--YFDSLNGE--IDMAVCRSFMLQLLRGLAFCHSHNVLHRDLKPQNLLINKNG 138
Query: 325 CVKIGDLGLARKFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAEL 384
+K+ D GLAR F V+ Y+ + +VT+WYR P+++ GA+ YT +ID+W+ GCI AEL
Sbjct: 139 ELKLADFGLARAFGIPVK-CYSAE--VVTLWYRPPDVLFGAKLYTTSIDMWSAGCILAEL 195
Query: 385 IGL-RPIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPK 443
RP+F G + +Q KI V+G+P+ WP + +Y+ L P
Sbjct: 196 ADAGRPLFPGSDV-----------LDQLMKIFRVLGTPNEDSWPGVSHLSDYVALPSFPA 244
Query: 444 YRDNLTAWYQTAGGKDKTALDILYRLLQYDPIKRIDAIDALDHVYFTN 491
+T+W Q + D+L +LL P +RI A A+ H YFT+
Sbjct: 245 ----ITSWSQLVPRLNSKGRDLLQKLLICRPNQRISAEAAMQHPYFTD 288
>SPAC2F3.15 [D] KOG0600 Cdc2-related protein kinase
Length = 593
Score = 159 bits (403), Expect = 9e-39
Identities = 91/292 (31%), Positives = 153/292 (52%), Gaps = 33/292 (11%)
Query: 209 AIKKFKTEREGVEHYTGISQSACREMSLCRELDNNHLTKLVEIFLEKKSIYMVSEFAEHD 268
A+K+ + E+E G + RE+ + + L + ++ +L+EI +EK S+YMV E+ +HD
Sbjct: 304 ALKRIRLEQEK----DGFPITTVREVKILQRLRHKNIVRLLEIMVEKSSVYMVFEYMDHD 359
Query: 269 LLQII-----HFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVD 323
L ++ HF P +K + QI + ++YLH +LHRD+K +NI++ +
Sbjct: 360 LTGVLLNSQLHF---------TPGNIKHLSKQIFEALAYLHHRGVLHRDIKGSNILLNNN 410
Query: 324 GCVKIGDLGLARKFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAE 383
G +K D GLAR + YT ++T+W+R PEL+LG Y A+D+W+ GCI E
Sbjct: 411 GDLKFADFGLARFNTSSKSANYTNR--VITLWFRPPELLLGETAYDTAVDIWSAGCIVME 468
Query: 384 LIGLRPIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPK 443
L +P F+G + + +Q + I ++MG+PD WP + + P Y L + +
Sbjct: 469 LFTGKPFFQGRD-----------EISQLEVIYDMMGTPDVHSWPEVKNLPWYELLKPVEE 517
Query: 444 YRDNLTAWYQTAGGKDKTALDILYRLLQYDPIKRIDAIDALDHVYFTNGDPP 495
+ ++ A+D+ +LL +P R A + L H YFT+ PP
Sbjct: 518 KKSRFVETFKEI--LSPAAIDLCQKLLALNPFCRPSAHETLMHEYFTSESPP 567
>CE21213 [UT] KOG0662 Cyclin-dependent kinase CDK5
Length = 292
Score = 159 bits (403), Expect = 9e-39
Identities = 89/268 (33%), Positives = 145/268 (53%), Gaps = 23/268 (8%)
Query: 225 GISQSACREMSLCRELDNNHLTKLVEIFLEKKSIYMVSEFAEHDLLQIIHFHSHPEKRLI 284
G+ SA RE+ + REL + ++ +L ++ + + +V E+ + DL + + +
Sbjct: 43 GVPSSALREICILRELKHRNVVRLYDVVHSENKLTLVFEYCDQDLKKFFDSLNG----YM 98
Query: 285 PPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGCVKIGDLGLARKFNNMVQTL 344
+ +S+M Q+L G+S+ H + +LHRDLKP N+++ +G +K+ D GLAR F V+
Sbjct: 99 DAQTARSLMLQLLRGLSFCHAHHVLHRDLKPQNLLINTNGTLKLADFGLARAFGVPVRCF 158
Query: 345 YTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELIGL-RPIFKGEEAKMESKKS 403
+VT+WYR P+++ GA+ Y +ID+W+ GCIFAE+ RP+F G +
Sbjct: 159 ---SAEVVTLWYRPPDVLFGAKLYNTSIDMWSAGCIFAEISNAGRPLFPGADVD------ 209
Query: 404 VLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPKYRDNLTAWYQTAGGKDKTAL 463
+Q ++I + +GSP WP+I P+Y P Y LT W Q +
Sbjct: 210 -----DQLKRIFKQLGSPSEDNWPSITQLPDY---KPYPIYHPTLT-WSQIVPNLNSRGR 260
Query: 464 DILYRLLQYDPIKRIDAIDALDHVYFTN 491
D+L +LL +P RIDA AL H YF +
Sbjct: 261 DLLQKLLVCNPAGRIDADAALRHAYFAD 288
>At1g76540 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 313
Score = 159 bits (403), Expect = 9e-39
Identities = 94/276 (34%), Positives = 162/276 (58%), Gaps = 27/276 (9%)
Query: 221 EHYTGISQSACREMSLCRELDNN-HLTKLVEIF--LEKKS---IYMVSEFAEHDLLQIIH 274
E G+ + RE+S+ R L + H+ +L+++ L K+ +Y+V E+ + D+ + I
Sbjct: 49 EDEEGVPSTTLREISILRMLARDPHVVRLMDVKQGLSKEGKTVLYLVFEYMDTDVKKFIR 108
Query: 275 FHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGC-VKIGDLGL 333
K IP + +KS+M+Q+ G+++ H + ILHRDLKP N+++ +KI DLGL
Sbjct: 109 SFRSTGKN-IPTQTIKSLMYQLCKGMAFCHGHGILHRDLKPHNLLMDPKTMRLKIADLGL 167
Query: 334 ARKFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELIGLRPIFKG 393
AR F + YT + I+T+WYRAPE++LGA HY+ A+D+W+VGCIFAEL+ + IF+G
Sbjct: 168 ARAFT-LPMKKYTHE--ILTLWYRAPEVLLGATHYSTAVDMWSVGCIFAELVTNQAIFQG 224
Query: 394 EEAKMESKKSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPKYRDNLTAWYQ 453
+ + Q I ++ G+P+ ++WP + + + + P+++ + +
Sbjct: 225 DS-----------ELQQLLHIFKLFGTPNEEMWPGVSTLKNW---HEYPQWKPSTLS--S 268
Query: 454 TAGGKDKTALDILYRLLQYDPIKRIDAIDALDHVYF 489
D+ +D+L ++LQY+P KRI A A++H YF
Sbjct: 269 AVPNLDEAGVDLLSKMLQYEPAKRISAKMAMEHPYF 304
>YDL108w [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 306
Score = 159 bits (402), Expect = 1e-38
Identities = 102/288 (35%), Positives = 152/288 (52%), Gaps = 26/288 (9%)
Query: 209 AIKKFKTEREGVEHYTGISQSACREMSLCRELDNNHLTKLVEIFLEKKSIYMVSEFAEHD 268
AIK+ KT E G+ SA RE+ +E+ + ++ +L++IF+ ++ +V EF D
Sbjct: 34 AIKEIKTS----EFKDGLDMSAIREVKYLQEMQHPNVIELIDIFMAYDNLNLVLEFLPTD 89
Query: 269 LLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGCVKI 328
L +I S L P +K+ M L GV + H+N+ILHRDLKP N++ + DG +K+
Sbjct: 90 LEVVIKDKSI----LFTPADIKAWMLMTLRGVYHCHRNFILHRDLKPNNLLFSPDGQIKV 145
Query: 329 GDLGLARKFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELIGLR 388
D GLAR + L + +VT WYRAPEL+ GA+HYT AID+W+VG IFAEL+
Sbjct: 146 ADFGLARAIPAPHEILTSN---VVTRWYRAPELLFGAKHYTSAIDIWSVGVIFAELMLRI 202
Query: 389 PIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQL-AKMPKYRDN 447
P G+ +Q + +G+P + WP + S+ Y +L P RD
Sbjct: 203 PYLPGQN-----------DVDQMEVTFRALGTPTDRDWPEVSSFMTYNKLQIYPPPSRDE 251
Query: 448 LTAWYQTAGGKDKTALDILYRLLQYDPIKRIDAIDALDHVYFTNGDPP 495
L + A + ALD + +L +P KR A+ L+ YF PP
Sbjct: 252 LRKRFIAA---SEYALDFMCGMLTMNPQKRWTAVQCLESDYFKELPPP 296
>CE03811 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 763
Score = 158 bits (399), Expect = 3e-38
Identities = 88/287 (30%), Positives = 160/287 (55%), Gaps = 21/287 (7%)
Query: 209 AIKKFKTEREGVEHYTGISQSACREMSLCRELD-NNHLTKLVEIFL--EKKSIYMVSEFA 265
A+K+FK E+E G +A RE+++ + + ++ + EI + K +YM E+
Sbjct: 426 ALKRFKMEKEK----EGFPITALREINMLLKAGAHENIVNVKEILVGSTKTEVYMAMEYV 481
Query: 266 EHDLLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGC 325
EHD+ +I +R + K++M Q+L G+ ++H+ WILHRDLK +N++++ G
Sbjct: 482 EHDVKSLIDKMRSRNQRFKTGQQ-KTLMSQLLSGIEHMHKLWILHRDLKTSNLLISHSGI 540
Query: 326 VKIGDLGLARKFNNM--VQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAE 383
+KI D GLAR++ ++ ++VT+WYR+PEL+L + Y+ +D+W++GCI AE
Sbjct: 541 LKIADFGLAREYGEARDIEKRMKLTPIVVTLWYRSPELLLEPKTYSTPVDMWSIGCIMAE 600
Query: 384 LIGLRPIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPK 443
I ++P+F+G+ + NQ +I ++MG+P +IWP+I + + P
Sbjct: 601 FIMMKPMFQGDS-----------EPNQVHQIFQMMGTPTEQIWPDIKELKVWNMVEFPPV 649
Query: 444 YRDNLTAWYQTAGGKDKTALDILYRLLQYDPIKRIDAIDALDHVYFT 490
L ++ ++T D+L +L +P R+ A +AL H +F+
Sbjct: 650 KPGQLRRIFKGEKLVNETGFDLLNGMLCLNPANRLTASEALQHDWFS 696
>7303804 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 387
Score = 158 bits (399), Expect = 3e-38
Identities = 93/292 (31%), Positives = 152/292 (51%), Gaps = 29/292 (9%)
Query: 206 QFYAIKKFKTEREGVEHYTGISQSACREMSLCRELDNNHLTKLVEIFLEKK--SIYMVSE 263
+ A+KK + ++E G+ S RE+ + ++ + ++ +L E+ + K SI++V +
Sbjct: 77 EIVALKKVRMDQEK----DGLPISGLREIMILKQCHHENIVRLREVVVGKSLDSIFLVMD 132
Query: 264 FAEHDLLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVD 323
F E DL ++ S P +K I Q+L + YLH +++HRDLK +N+++T
Sbjct: 133 FCEQDLASVLDNMSQP----FTESEVKCITLQVLKALKYLHSRFMIHRDLKVSNLLMTDK 188
Query: 324 GCVKIGDLGLARKFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAE 383
GC+K+ D GLAR F+N + + +VT+WYRAPEL+LG R +T A+D+WA GCI E
Sbjct: 189 GCIKVADFGLARMFSNPPKPM---TPQMVTLWYRAPELLLGCRTHTTAVDMWAFGCILGE 245
Query: 384 LIGLRPIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPK 443
L+ +P+ G + Q I++++G+P IWP P +
Sbjct: 246 LLLGKPLLPGNS-----------EIAQLDMIIDLLGAPSESIWPGFADLPAVQNFTLSQQ 294
Query: 444 YRDNLTAWYQTAGGKDKTALDILYRLLQYDPIKRIDAIDALDHVYFTNGDPP 495
+NLT + G + L+IL+ Y+P R A + L YF DPP
Sbjct: 295 PYNNLTPKFHMIGQSGRNLLNILF---IYNPKTRATAEECLKSKYFV--DPP 341
>7291442 [D] KOG0669 Cyclin T-dependent kinase CDK9
Length = 404
Score = 156 bits (394), Expect = 1e-37
Identities = 102/306 (33%), Positives = 157/306 (50%), Gaps = 33/306 (10%)
Query: 201 KPSQIQFYAIKKFKTEREGVEHYTGISQSACREMSLCRELDNNHLTKLVEIFLEK----- 255
K +F A+KK + E G +A RE+ + + L + ++ L+EI K
Sbjct: 70 KKGNKKFVAMKKVLMDNEK----EGFPITALREIRILQLLKHENVVNLIEICRTKATATN 125
Query: 256 ---KSIYMVSEFAEHDLLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRD 312
+ Y+V +F EHDL ++ S+ + +K +M Q+L+G+ Y+H N ILHRD
Sbjct: 126 GYRSTFYLVFDFCEHDLAGLL---SNMNVKFSLGE-IKKVMQQLLNGLYYIHSNKILHRD 181
Query: 313 LKPANIMVTVDGCVKIGDLGLARKFN---NMVQTLYTGDKVIVTIWYRAPELILGARHYT 369
+K AN+++T G +K+ D GLAR F+ N + YT +VT+WYR PEL+LG R+Y
Sbjct: 182 MKAANVLITKHGILKLADFGLARAFSIPKNESKNRYTNR--VVTLWYRPPELLLGDRNYG 239
Query: 370 PAIDLWAVGCIFAELIGLRPIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHKIWPNI 429
P +D+W GCI AE+ PI +G + Q I ++ GS +WP +
Sbjct: 240 PPVDMWGAGCIMAEMWTRSPIMQGNT-----------EQQQLTFISQLCGSFTPDVWPGV 288
Query: 430 DSYPEYLQLAKMPKYRDNLTAWYQTAGGKDKTALDILYRLLQYDPIKRIDAIDALDHVYF 489
+ Y + ++PK + KD+T D+L +LL DP KRIDA AL+H +F
Sbjct: 289 EELELYKSI-ELPKNQKRRVKERLRPYVKDQTGCDLLDKLLTLDPKKRIDADTALNHDFF 347
Query: 490 TNGDPP 495
P
Sbjct: 348 WTDPMP 353
>At1g20930 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 315
Score = 155 bits (393), Expect = 1e-37
Identities = 90/276 (32%), Positives = 156/276 (55%), Gaps = 27/276 (9%)
Query: 221 EHYTGISQSACREMSLCRELDNN-HLTKLVEIFLE-----KKSIYMVSEFAEHDLLQIIH 274
E G+ + RE+S+ R L + H+ +L+++ K +Y+V E+ + DL + I
Sbjct: 51 EDEEGVPPTTLREISILRMLARDPHIVRLMDVKQGINKEGKTVLYLVFEYVDTDLKKFIR 110
Query: 275 FHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGC-VKIGDLGL 333
+ IP +K +M+Q+ G+++ H + +LHRDLKP N+++ +KI DLGL
Sbjct: 111 SFRQAGQN-IPQNTVKCLMYQLCKGMAFCHGHGVLHRDLKPHNLLMDRKTMTLKIADLGL 169
Query: 334 ARKFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELIGLRPIFKG 393
AR F + YT + I+T+WYRAPE++LGA HY+ +D+W+VGCIFAEL+ + IF G
Sbjct: 170 ARAFT-LPMKKYTHE--ILTLWYRAPEVLLGATHYSTGVDMWSVGCIFAELVTKQAIFAG 226
Query: 394 EEAKMESKKSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPKYRDNLTAWYQ 453
+ + Q +I ++G+P+ ++WP + ++ + P+++ +
Sbjct: 227 DS-----------ELQQLLRIFRLLGTPNEEVWPGVSKLKDW---HEYPQWKP--LSLST 270
Query: 454 TAGGKDKTALDILYRLLQYDPIKRIDAIDALDHVYF 489
D+ LD+L ++L+Y+P KRI A A++H YF
Sbjct: 271 AVPNLDEAGLDLLSKMLEYEPAKRISAKKAMEHPYF 306
>Hs4505649 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 523
Score = 155 bits (392), Expect = 2e-37
Identities = 89/277 (32%), Positives = 151/277 (54%), Gaps = 21/277 (7%)
Query: 220 VEHYTGISQSACREMSLCRELDNNHLTKLVEIFLEKKSIYMVSEFAEHDLLQIIHFHSHP 279
+EH G +A RE+SL ++L + ++ L +I KS+ +V E+ + DL Q + +
Sbjct: 225 LEHEEGAPCTAIREVSLLKDLKHANIVTLHDIVHTDKSLTLVFEYLDKDLKQYMDDCGN- 283
Query: 280 EKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGCVKIGDLGLARKFNN 339
++ +K ++QIL G++Y H+ +LHRDLKP N+++ G +K+ D GLAR +
Sbjct: 284 ---IMSMHNVKLFLYQILRGLAYCHRRKVLHRDLKPQNLLINEKGELKLADFGLARAKSV 340
Query: 340 MVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELIGLRPIFKGEEAKME 399
+T Y+ + +VT+WYR P+++LG+ Y ID+W VGCIF E+ RP+F G +
Sbjct: 341 PTKT-YSNE--VVTLWYRPPDVLLGSSEYLTQIDMWGVGCIFFEMASGRPLFPGSTVE-- 395
Query: 400 SKKSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPKYRDNLTAWYQTAGGKD 459
++ I ++G+P + WP I S E+ PKY+ A D
Sbjct: 396 ---------DELHLIFRLLGTPSQETWPGISSNEEFKNY-NFPKYKPE--PLINHAPRLD 443
Query: 460 KTALDILYRLLQYDPIKRIDAIDALDHVYFTNGDPPV 496
++++ + LQY+ KR+ A +A+ HVYF + P +
Sbjct: 444 SEGIELIRKFLQYESKKRVSAEEAMKHVYFRSLGPRI 480
>7296346 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 952
Score = 155 bits (392), Expect = 2e-37
Identities = 92/301 (30%), Positives = 163/301 (53%), Gaps = 24/301 (7%)
Query: 206 QFYAIKKFKTEREGVEHYTGISQSACREMSLCRELDNNHLTKLVEIFLEKK--SIYMVSE 263
+ A+K+ K E+E G ++ RE++ + + ++ + EI + I++V +
Sbjct: 582 EIVALKRLKMEKEK----EGFPITSLREINTLLKGQHPNIVTVREIVVGSNMDKIFIVMD 637
Query: 264 FAEHDLLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVD 323
+ EHDL ++ + ++ P + K + Q+L V++LH NWILHRDLK +N++++
Sbjct: 638 YVEHDLKSLMETMKNRKQSFFPGEV-KCLTQQLLRAVAHLHDNWILHRDLKTSNLLLSHK 696
Query: 324 GCVKIGDLGLARKFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAE 383
G +K+GD GLAR++ + ++ YT ++VT+WYRAPEL+L + Y+ ID+W+VGCIFAE
Sbjct: 697 GILKVGDFGLAREYGSPIKK-YT--SLVVTLWYRAPELLLCSPVYSTPIDVWSVGCIFAE 753
Query: 384 LIGLRPIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPK 443
+ + P+F G+ + ++ +I + +G+P+ KIWP P +
Sbjct: 754 FLQMLPLFPGKS-----------EIDELNRIFKELGTPNEKIWPGYTELPAVKNMLSQNS 802
Query: 444 YRDNLTAWYQTAGGKDKTA---LDILYRLLQYDPIKRIDAIDALDHVYFTNGDPPVCENV 500
++KT+ L +L LL YDP +R+ A AL H +F P+ ++
Sbjct: 803 QFTEYPVSQLRKHFQEKTSEMGLSLLQGLLTYDPKQRLSADAALKHGFFKELPLPIDPSM 862
Query: 501 F 501
F
Sbjct: 863 F 863
>ECU08g1920 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 296
Score = 154 bits (389), Expect = 4e-37
Identities = 91/294 (30%), Positives = 155/294 (51%), Gaps = 33/294 (11%)
Query: 209 AIKKFKTEREGVEHYTGISQSACREMSLCRELDNNHLTKLVEIFLEKKSIYMVSEFAEHD 268
A+KK + E E GI + RE+ L + L ++ + +L ++ +Y+V E+ E D
Sbjct: 32 ALKKIRLENEN----EGIPATTIREILLLKNLKHSTIVELSDVIYNNNKMYLVFEYVELD 87
Query: 269 LLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGCVKI 328
L + + S E RL+ ++ + Q+L + Y H I HRDLKP NI+V +K+
Sbjct: 88 LRRYLDRMSD-EGRLVEEGFVRKMSQQLLTAMEYCHSRNIFHRDLKPQNILVDPKENIKL 146
Query: 329 GDLGLARKFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELIGLR 388
D GL R ++T YT + +VT+WYR PEL+LG ++Y ++D+W+ CI AE++ +R
Sbjct: 147 ADFGLGRAAGIPLRT-YTTE--VVTLWYRPPELLLGCKYYDASVDVWSAACIMAEVVLMR 203
Query: 389 PIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPKYRDNL 448
P F G+ + +Q +I +V+G+P++ W N++++ P Y+
Sbjct: 204 PFFPGDS-----------EIDQLFRIFKVLGTPNNSRWSNVENF---------PNYKVEF 243
Query: 449 TAW----YQTAGGKDKTALDILYRLLQYDPIKRIDAIDALDHVYFTNGDPPVCE 498
W +T D +D++ ++L+YDP R+ A + L H YF G P + E
Sbjct: 244 PVWDPVDLKTIFRGDPDFVDLISKMLEYDPKMRMTAKNGLSHKYF-EGMPLIME 296
>Hs5453860 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 496
Score = 154 bits (388), Expect = 5e-37
Identities = 92/270 (34%), Positives = 149/270 (55%), Gaps = 21/270 (7%)
Query: 220 VEHYTGISQSACREMSLCRELDNNHLTKLVEIFLEKKSIYMVSEFAEHDLLQIIHFHSHP 279
+EH G +A RE+SL ++L + ++ L +I +KS+ +V E+ + DL Q + +
Sbjct: 198 LEHEEGAPCTAIREVSLLKDLKHANIVTLHDIIHTEKSLTLVFEYLDKDLKQYLDDCGN- 256
Query: 280 EKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGCVKIGDLGLARKFNN 339
+I +K ++Q+L G++Y H+ +LHRDLKP N+++ G +K+ D GLAR +
Sbjct: 257 ---IINMHNVKLFLFQLLRGLAYCHRQKVLHRDLKPQNLLINERGELKLADFGLARAKSI 313
Query: 340 MVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELIGLRPIFKGEEAKME 399
+T Y+ + +VT+WYR P+++LG+ Y+ ID+W VGCIF E+ RP+F G +
Sbjct: 314 PTKT-YSNE--VVTLWYRPPDILLGSTDYSTQIDMWGVGCIFYEMATGRPLFPGSTVE-- 368
Query: 400 SKKSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPKYRDNLTAWYQTAGGKD 459
Q I ++G+P + WP I S E+ + PKYR A A D
Sbjct: 369 ---------EQLHFIFRILGTPTEETWPGILSNEEF-KTYNYPKYR--AEALLSHAPRLD 416
Query: 460 KTALDILYRLLQYDPIKRIDAIDALDHVYF 489
D+L +LLQ++ RI A DA+ H +F
Sbjct: 417 SDGADLLTKLLQFEGRNRISAEDAMKHPFF 446
>Hs15011928 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 448
Score = 154 bits (388), Expect = 5e-37
Identities = 92/270 (34%), Positives = 149/270 (55%), Gaps = 21/270 (7%)
Query: 220 VEHYTGISQSACREMSLCRELDNNHLTKLVEIFLEKKSIYMVSEFAEHDLLQIIHFHSHP 279
+EH G +A RE+SL ++L + ++ L +I +KS+ +V E+ + DL Q + +
Sbjct: 150 LEHEEGAPCTAIREVSLLKDLKHANIVTLHDIIHTEKSLTLVFEYLDKDLKQYLDDCGN- 208
Query: 280 EKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGCVKIGDLGLARKFNN 339
+I +K ++Q+L G++Y H+ +LHRDLKP N+++ G +K+ D GLAR +
Sbjct: 209 ---IINMHNVKLFLFQLLRGLAYCHRQKVLHRDLKPQNLLINERGELKLADFGLARAKSI 265
Query: 340 MVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELIGLRPIFKGEEAKME 399
+T Y+ + +VT+WYR P+++LG+ Y+ ID+W VGCIF E+ RP+F G +
Sbjct: 266 PTKT-YSNE--VVTLWYRPPDILLGSTDYSTQIDMWGVGCIFYEMATGRPLFPGSTVE-- 320
Query: 400 SKKSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPKYRDNLTAWYQTAGGKD 459
Q I ++G+P + WP I S E+ + PKYR A A D
Sbjct: 321 ---------EQLHFIFRILGTPTEETWPGILSNEEF-KTYNYPKYR--AEALLSHAPRLD 368
Query: 460 KTALDILYRLLQYDPIKRIDAIDALDHVYF 489
D+L +LLQ++ RI A DA+ H +F
Sbjct: 369 SDGADLLTKLLQFEGRNRISAEDAMKHPFF 398
>YKL139w [D] KOG0600 Cdc2-related protein kinase
Length = 528
Score = 153 bits (386), Expect = 8e-37
Identities = 104/338 (30%), Positives = 170/338 (49%), Gaps = 38/338 (11%)
Query: 209 AIKKFKTEREGVEHYTGISQSACREMSLCRELDNNHLTKLVEIFLE-KKSIYMVSEFAEH 267
A+KK + + E G ++ RE+ L + D+ +++ + EI +E +K++YM+ E+A++
Sbjct: 210 ALKKLRLQGER----EGFPITSIREIKLLQSFDHPNVSTIKEIMVESQKTVYMIFEYADN 265
Query: 268 DLLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGCVK 327
DL ++ ++ I K + Q+L G+ YLH N ILHRD+K +NI++ G +K
Sbjct: 266 DLSGLLL----NKEVQISHSQCKHLFKQLLLGMEYLHDNKILHRDVKGSNILIDNQGNLK 321
Query: 328 IGDLGLARKFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELIGL 387
I D GLARK N+ YT ++T+WYR PEL+LG +Y +D+W GC+ EL
Sbjct: 322 ITDFGLARKMNSRAD--YTNR--VITLWYRPPELLLGTTNYGTEVDMWGCGCLLVELFNK 377
Query: 388 RPIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQL--AKMPKYR 445
IF+G + Q + I ++MG+P WP + P + + + KY
Sbjct: 378 TAIFQGSN-----------ELEQIESIFKIMGTPTINSWPTLYDMPWFFMIMPQQTTKYV 426
Query: 446 DNLTAWYQTAGGKDKTALDILYRLLQYDPIKRIDAIDALDHVYF---TNGDPPVCENVFE 502
+N + +++ K L + LL YD KR A +AL YF +P V + +
Sbjct: 427 NNFSEKFKSVLPSSK-CLQLAINLLCYDQTKRFSATEALQSDYFKEEPKPEPLVLDGLVS 485
Query: 503 GLNYKYP-------PRRIHTNDNDITNVGNDNNQANHS 533
Y+ P + TN N+ N GN NN N++
Sbjct: 486 CHEYEVKLARKQKRPNILSTNTNNKGN-GNSNNNNNNN 522
>At2g38620 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 311
Score = 150 bits (379), Expect = 5e-36
Identities = 100/302 (33%), Positives = 169/302 (55%), Gaps = 42/302 (13%)
Query: 209 AIKKFKTEREGVEHYTGISQSACREMSLCRELDNN-HLTKL--VEIFLEKK--------- 256
A+KK + E + GI +A RE+SL + L + ++ +L VE ++ K
Sbjct: 31 ALKKTRLEMDE----EGIPPTALREISLLQMLSQSIYIVRLLCVEHVIQSKDSTVSHSPK 86
Query: 257 -SIYMVSEFAEHDLLQIIHFH---SHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRD 312
++Y+V E+ + DL + I H S+P R + +++ M+Q+ GV++ H + +LHRD
Sbjct: 87 SNLYLVFEYLDTDLKKFIDSHRKGSNP--RPLEASLVQRFMFQLFKGVAHCHSHGVLHRD 144
Query: 313 LKPANIMVTVD-GCVKIGDLGLARKFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPA 371
LKP N+++ D G +KI DLGL+R F ++ YT + IVT+WYRAPE++LG+ HY+ A
Sbjct: 145 LKPQNLLLDKDKGILKIADLGLSRAFTVPLKA-YTHE--IVTLWYRAPEVLLGSTHYSTA 201
Query: 372 IDLWAVGCIFAELIGLRPIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHKIWPNIDS 431
+D+W+VGCIFAE+I + +F G+ + Q I ++G+P + WP + +
Sbjct: 202 VDIWSVGCIFAEMIRRQALFPGDS-----------EFQQLLHIFRLLGTPTEQQWPGVMA 250
Query: 432 YPEYLQLAKMPKYRDNLTAWYQTAGGKDKTALDILYRLLQYDPIKRIDAIDALDHVYFTN 491
++ PK+ + + +D+L ++L+Y+P +RI A ALDH YF +
Sbjct: 251 LRDW---HVYPKWEPQDLS--RAVPSLSPEGIDLLTQMLKYNPAERISAKAALDHPYFDS 305
Query: 492 GD 493
D
Sbjct: 306 LD 307
>7296451 [D] KOG0600 Cdc2-related protein kinase
Length = 1157
Score = 150 bits (379), Expect = 5e-36
Identities = 99/288 (34%), Positives = 152/288 (52%), Gaps = 37/288 (12%)
Query: 209 AIKKFKTEREGVEHYTGISQSACREMSLCRELDNNHLTKLVEIFLEKK----------SI 258
A+KK + E E G +A RE+ + R+L++ ++ L EI +K+ S
Sbjct: 831 ALKKVRLEHEK----EGFPITAVREIKILRQLNHRNIVNLHEIVTDKQDAVEFRKDKGSF 886
Query: 259 YMVSEFAEHDLLQIIHFHSHPEKRLIP--PRMLKSIMWQILDGVSYLHQNWILHRDLKPA 316
Y+V E+ +HDL+ ++ E ++ SIM Q+LDG++Y H+ LHRD+K +
Sbjct: 887 YLVFEYMDHDLMGLL------ESGMVDFNEENNASIMKQLLDGLNYCHKKNFLHRDIKCS 940
Query: 317 NIMVTVDGCVKIGDLGLARKFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWA 376
NI++ G VK+ D GLAR +N + +KVI T+WYR PEL+LG Y P+ID+W+
Sbjct: 941 NILMNNRGKVKLADFGLARLYNADDRERPYTNKVI-TLWYRPPELLLGEERYGPSIDVWS 999
Query: 377 VGCIFAELIGLRPIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEYL 436
GCI EL RP+F+ + Q + I ++ GSP +WPN+ P +
Sbjct: 1000 CGCILGELFVKRPLFQANA-----------EMAQLETISKICGSPVPAVWPNVIKLPLFH 1048
Query: 437 QLAKMPKYRDNLTAWYQTAGGKDKTALDILYRLLQYDPIKRIDAIDAL 484
L + +R L ++ ALD+L ++L DP KRI A DAL
Sbjct: 1049 TLKQKKTHRRRLREDFEF---MPAPALDLLDKMLDLDPDKRITAEDAL 1093
>At4g13020 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 443
Score = 150 bits (378), Expect = 7e-36
Identities = 90/259 (34%), Positives = 142/259 (54%), Gaps = 23/259 (8%)
Query: 232 REMSLCRELDNNHLTKLVEIFLEKKSIYMVSEFAEHDLLQIIHFHSHPEKRLIPPRMLKS 291
RE+ R+L++ H+ KL EI E ++ + E +H+L I+ P ++S
Sbjct: 57 REVKALRKLNHPHIIKLKEIVREHNELFFIFECMDHNLYHIMKERERP----FSEGEIRS 112
Query: 292 IMWQILDGVSYLHQNWILHRDLKPANIMVTVDGCVKIGDLGLARKFNNMVQTLYTGDKVI 351
M Q+L G++++H+N HRDLKP N++VT + +KI D GLAR+ +M YT + +
Sbjct: 113 FMSQMLQGLAHMHKNGYFHRDLKPENLLVT-NNILKIADFGLAREVASMPP--YT--EYV 167
Query: 352 VTIWYRAPELILGARHYTPAIDLWAVGCIFAELIGLRPIFKGEEAKMESKKSVLFQANQF 411
T WYRAPE++L + YTPA+D+WAVG I AEL L P+F GE + +Q
Sbjct: 168 STRWYRAPEVLLQSSLYTPAVDMWAVGAILAELYALTPLFPGES-----------EIDQL 216
Query: 412 QKILEVMGSPDHKIWPNIDSYPEYLQLAKMPKYRDNLTAWYQTAGGKDKTALDILYRLLQ 471
KI V+G PD +P S + ++ + + A + A+D++ RL
Sbjct: 217 YKICCVLGKPDWTTFPEAKSISRIMSISHTEFPQTRIADLLPNAAPE---AIDLINRLCS 273
Query: 472 YDPIKRIDAIDALDHVYFT 490
+DP+KR A +AL+H +F+
Sbjct: 274 WDPLKRPTADEALNHPFFS 292
>At3g54180 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 309
Score = 150 bits (378), Expect = 7e-36
Identities = 95/299 (31%), Positives = 166/299 (54%), Gaps = 38/299 (12%)
Query: 209 AIKKFKTEREGVEHYTGISQSACREMSLCRELDNN-HLTKLVEIF----------LEKKS 257
A+KK + E + GI +A RE+SL + L + ++ +L+ + K +
Sbjct: 31 ALKKTRLEMDE----EGIPPTALREISLLQMLSTSIYVVRLLCVEHVHQPSTKSQSTKSN 86
Query: 258 IYMVSEFAEHDLLQIIH-FHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPA 316
+Y+V E+ + DL + I + P + + P +++ +M+Q+ GV++ H + +LHRDLKP
Sbjct: 87 LYLVFEYLDTDLKKFIDSYRKGPNPKPLEPFLIQKLMFQLCKGVAHCHSHGVLHRDLKPQ 146
Query: 317 NIMVTVDG-CVKIGDLGLARKFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLW 375
N+++ D +KI DLGL R F +++ YT + IVT+WYRAPE++LG+ HY+ +D+W
Sbjct: 147 NLLLVKDKELLKIADLGLGRAFTVPLKS-YTHE--IVTLWYRAPEVLLGSTHYSTGVDMW 203
Query: 376 AVGCIFAELIGLRPIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEY 435
+VGCIFAE++ + +F G+ + Q I ++G+P + WP + + ++
Sbjct: 204 SVGCIFAEMVRRQALFPGDS-----------EFQQLLHIFRLLGTPTEQQWPGVSTLRDW 252
Query: 436 LQLAKMPKYR-DNLTAWYQTAGGKDKTALDILYRLLQYDPIKRIDAIDALDHVYFTNGD 493
PK+ +LT +D+L ++L+Y+P +RI A ALDH YF + D
Sbjct: 253 ---HVYPKWEPQDLTL---AVPSLSPQGVDLLTKMLKYNPAERISAKTALDHPYFDSLD 305
>Hs6912584 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 451
Score = 149 bits (375), Expect = 2e-35
Identities = 112/406 (27%), Positives = 188/406 (45%), Gaps = 29/406 (7%)
Query: 139 NSINRSTRQQEANDNLTTMDFRKPSHK--RFTPPNNSNSTQIRSNSGSEXXXXXXXXXXX 196
N + R + A N T K S K R + P++ S + E
Sbjct: 70 NQVKRVHSENNACINFKTSSTGKESPKVRRHSSPSSPTSPKFGKADSYEKLEKLGEGSYA 129
Query: 197 XXXXKPSQI--QFYAIKKFKTEREGVEHYTGISQSACREMSLCRELDNNHLTKLVEIFLE 254
S++ + A+K + + E +T I RE SL + L + ++ L +I
Sbjct: 130 TVYKGKSKVNGKLVALKVIRLQEEEGTPFTAI-----REASLLKGLKHANIVLLHDIIHT 184
Query: 255 KKSIYMVSEFAEHDLLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLK 314
K+++ +V E+ DL Q + HP + P +K ++Q+L G+SY+HQ +ILHRDLK
Sbjct: 185 KETLTLVFEYVHTDLCQ--YMDKHPGG--LHPDNVKLFLFQLLRGLSYIHQRYILHRDLK 240
Query: 315 PANIMVTVDGCVKIGDLGLARKFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDL 374
P N++++ G +K+ D GLAR ++ Y+ + +VT+WYR P+++LG+ Y+ +D+
Sbjct: 241 PQNLLISDTGELKLADFGLARA-KSVPSHTYSNE--VVTLWYRPPDVLLGSTEYSTCLDM 297
Query: 375 WAVGCIFAELIGLRPIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHKIWPNIDSYPE 434
W VGCIF E+I F G K + +Q ++I V+G+P+ WP + S P
Sbjct: 298 WGVGCIFVEMIQGVAAFPG-------MKDI---QDQLERIFLVLGTPNEDTWPGVHSLPH 347
Query: 435 YL-QLAKMPKYRDNLTAWYQTAGGKDKTALDILYRLLQYDPIKRIDAIDALDHVYFTNGD 493
+ + + ++ AW + + A D+ +LLQ P R+ A AL H YF++
Sbjct: 348 FKPERFTLYSSKNLRQAWNKLS--YVNHAEDLASKLLQCSPKNRLSAQAALSHEYFSDLP 405
Query: 494 PPVCENVFEGLNYKYPPRRIHTNDNDITNVGNDNNQANHSQKQPMH 539
P + E + P R+ + NN S H
Sbjct: 406 PRLWELTDMSSIFTVPNVRLQPEAGESMRAFGKNNSYGKSLSNSKH 451
>At4g11330 [T] KOG0660 Mitogen-activated protein kinase
Length = 373
Score = 148 bits (374), Expect = 2e-35
Identities = 97/280 (34%), Positives = 155/280 (54%), Gaps = 33/280 (11%)
Query: 232 REMSLCRELDNNHLTKLVEIFLEKKS-----IYMVSEFAEHDLLQIIHFHSHPEKRLIPP 286
RE+ L R L++ ++ + +I K +Y+V E + DL QII + +
Sbjct: 86 REIKLLRHLEHENVVVIKDIIRPPKKEDFVDVYIVFELMDTDLHQIIR-----SNQSLND 140
Query: 287 RMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGCVKIGDLGLARKFNNMVQTLYT 346
+ ++QIL G+ Y+H +LHRDLKP+N+++ + +KI D GLAR + +T Y
Sbjct: 141 DHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNSNCDLKITDFGLARTTS---ETEYM 197
Query: 347 GDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELIGLRPIFKGEEAKMESKKSVLF 406
+ V VT WYRAPEL+L + YT AID+W+VGCIFAE++ P+F G++
Sbjct: 198 TEYV-VTRWYRAPELLLNSSEYTSAIDVWSVGCIFAEIMTREPLFPGKD----------- 245
Query: 407 QANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPKY-RDNLTAWYQTAGGKDKTALDI 465
+Q + I E++GSPD + S + ++PK+ R N +A + + + TA+D+
Sbjct: 246 YVHQLKLITELIGSPDGASLEFLRSANARKYVKELPKFPRQNFSARFPS---MNSTAIDL 302
Query: 466 LYRLLQYDPIKRIDAIDALDHVYFTN----GDPPVCENVF 501
L ++L +DP+KRI +AL + Y + D PVC N F
Sbjct: 303 LEKMLVFDPVKRITVEEALCYPYLSALHDLNDEPVCSNHF 342
>Hs4502741 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 326
Score = 147 bits (372), Expect = 3e-35
Identities = 98/313 (31%), Positives = 158/313 (50%), Gaps = 42/313 (13%)
Query: 206 QFYAIKKFKTEREGVEHYTGISQSACREMSLCRELDNNHLTKLVEIFL--------EKKS 257
+F A+K+ + + G E G+ S RE+++ R L+ +V +F +
Sbjct: 38 RFVALKRVRVQT-GEE---GMPLSTIREVAVLRHLETFEHPNVVRLFDVCTVSRTDRETK 93
Query: 258 IYMVSEFAEHDLLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPAN 317
+ +V E + DL + P +P +K +M+Q+L G+ +LH + ++HRDLKP N
Sbjct: 94 LTLVFEHVDQDLTTYLDKVPEPG---VPTETIKDMMFQLLRGLDFLHSHRVVHRDLKPQN 150
Query: 318 IMVTVDGCVKIGDLGLARKFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAV 377
I+VT G +K+ D GLAR ++ + V+VT+WYRAPE++L + + TP +DLW+V
Sbjct: 151 ILVTSSGQIKLADFGLARIYSFQMAL----TSVVVTLWYRAPEVLLQSSYATP-VDLWSV 205
Query: 378 GCIFAELIGLRPIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQ 437
GCIFAE+ +P+F+G +Q KIL+V+G P + WP + P
Sbjct: 206 GCIFAEMFRRKPLFRGSS-----------DVDQLGKILDVIGLPGEEDWPRDVALPRQAF 254
Query: 438 LAKMPKYRDNLTAWYQTAGGKDKTALDILYRLLQYDPIKRIDAIDALDHVYFTNGDPPVC 497
+K + + D+ D+L + L ++P KRI A AL H YF +
Sbjct: 255 HSKSAQPIEKFVT------DIDELGKDLLLKCLTFNPAKRISAYSALSHPYFQD-----L 303
Query: 498 ENVFEGLNYKYPP 510
E E L+ PP
Sbjct: 304 ERCKENLDSHLPP 316
>Hs14110390 [D] KOG0600 Cdc2-related protein kinase
Length = 1452
Score = 147 bits (372), Expect = 3e-35
Identities = 91/304 (29%), Positives = 152/304 (49%), Gaps = 44/304 (14%)
Query: 206 QFYAIKKFKTEREGVEHYTGISQSACREMSLCRELDNNHLTKLVEIFLEKK--------- 256
+ A+KK + + E G +A RE+ + R+L + + + EI +K+
Sbjct: 729 EMVALKKVRLDNEK----EGFPITAIREIKILRQLTHQSIINMKEIVTDKEDALDFKKDK 784
Query: 257 -SIYMVSEFAEHDLLQI-----IHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILH 310
+ Y+V E+ +HDL+ + +HF+ + +KS M Q+++G+ Y H+ LH
Sbjct: 785 GAFYLVFEYMDHDLMGLLESGLVHFNENH---------IKSFMRQLMEGLDYCHKKNFLH 835
Query: 311 RDLKPANIMVTVDGCVKIGDLGLARKFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTP 370
RD+K +NI++ G +K+ D GLAR +++ YT ++T+WYR PEL+LG YTP
Sbjct: 836 RDIKCSNILLNNRGQIKLADFGLARLYSSEESRPYTNK--VITLWYRPPELLLGEERYTP 893
Query: 371 AIDLWAVGCIFAELIGLRPIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHKIWPNID 430
AID+W+ GCI EL +PIF+ + + Q + I + GSP +WP++
Sbjct: 894 AIDVWSCGCILGELFTKKPIFQANQ-----------ELAQLELISRICGSPCPAVWPDVI 942
Query: 431 SYPEYLQLAKMPKYRDNLTAWYQTAGGKDKTALDILYRLLQYDPIKRIDAIDALDHVYFT 490
P + + +YR L + ALD+ +L DP KR A AL +
Sbjct: 943 KLPYFNTMKPKKQYRRKLREEFVFI---PAAALDLFDYMLALDPSKRCTAEQALQCEFLR 999
Query: 491 NGDP 494
+ +P
Sbjct: 1000 DVEP 1003
>Hs14110387 [D] KOG0600 Cdc2-related protein kinase
Length = 1512
Score = 147 bits (372), Expect = 3e-35
Identities = 91/304 (29%), Positives = 152/304 (49%), Gaps = 44/304 (14%)
Query: 206 QFYAIKKFKTEREGVEHYTGISQSACREMSLCRELDNNHLTKLVEIFLEKK--------- 256
+ A+KK + + E G +A RE+ + R+L + + + EI +K+
Sbjct: 729 EMVALKKVRLDNEK----EGFPITAIREIKILRQLTHQSIINMKEIVTDKEDALDFKKDK 784
Query: 257 -SIYMVSEFAEHDLLQI-----IHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILH 310
+ Y+V E+ +HDL+ + +HF+ + +KS M Q+++G+ Y H+ LH
Sbjct: 785 GAFYLVFEYMDHDLMGLLESGLVHFNENH---------IKSFMRQLMEGLDYCHKKNFLH 835
Query: 311 RDLKPANIMVTVDGCVKIGDLGLARKFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTP 370
RD+K +NI++ G +K+ D GLAR +++ YT ++T+WYR PEL+LG YTP
Sbjct: 836 RDIKCSNILLNNRGQIKLADFGLARLYSSEESRPYTNK--VITLWYRPPELLLGEERYTP 893
Query: 371 AIDLWAVGCIFAELIGLRPIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHKIWPNID 430
AID+W+ GCI EL +PIF+ + + Q + I + GSP +WP++
Sbjct: 894 AIDVWSCGCILGELFTKKPIFQANQ-----------ELAQLELISRICGSPCPAVWPDVI 942
Query: 431 SYPEYLQLAKMPKYRDNLTAWYQTAGGKDKTALDILYRLLQYDPIKRIDAIDALDHVYFT 490
P + + +YR L + ALD+ +L DP KR A AL +
Sbjct: 943 KLPYFNTMKPKKQYRRKLREEFVFI---PAAALDLFDYMLALDPSKRCTAEQALQCEFLR 999
Query: 491 NGDP 494
+ +P
Sbjct: 1000 DVEP 1003
>At1g33770 [D] KOG0600 Cdc2-related protein kinase
Length = 614
Score = 147 bits (372), Expect = 3e-35
Identities = 100/283 (35%), Positives = 147/283 (51%), Gaps = 27/283 (9%)
Query: 232 REMSLCRELDNNHLTKLVEIFLEKKS--IYMVSEFAEHDLLQIIHFHSHPEKRLIPPRML 289
RE+++ R+LD+ ++ KL + K S +++V E+ EHDL + P + P+ +
Sbjct: 187 REINILRKLDHPNVMKLQCLVTSKLSGSLHLVFEYMEHDLSGLA---LRPGVKFTEPQ-I 242
Query: 290 KSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGCVKIGDLGLARKFNNMVQTLYTGDK 349
K M Q+L G+ + H ILHRD+K +N++V DG +KIGD GLA + T
Sbjct: 243 KCFMKQLLCGLEHCHSRGILHRDIKGSNLLVNNDGVLKIGDFGLASFYKPDQDQPLTSR- 301
Query: 350 VIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELIGLRPIFKGEEAKMESKKSVLFQAN 409
+VT+WYRAPEL+LG+ Y PAIDLW+VGCI AEL +PI G +
Sbjct: 302 -VVTLWYRAPELLLGSTEYGPAIDLWSVGCILAELFVCKPIMPGRT-----------EVE 349
Query: 410 QFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPKYRDNLTAWYQTAGGKDKTALDILYRL 469
Q KI ++ GSP + W N +P+ Y+ L +T ++LD+L +L
Sbjct: 350 QMHKIFKLCGSPSEEFW-NTTKFPQATSYKPQHPYKRVL---LETFKNLSSSSLDLLDKL 405
Query: 470 LQYDPIKRIDAIDALDHVYFTNGDPPVCENVFEGLNYKYPPRR 512
L +P KR A L +FT +P C L KYPP +
Sbjct: 406 LSVEPEKRCSASSTLLSEFFTT-EPLPCH--ISSLP-KYPPSK 444
>Hs7662388 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 632
Score = 147 bits (371), Expect = 4e-35
Identities = 100/297 (33%), Positives = 154/297 (51%), Gaps = 43/297 (14%)
Query: 206 QFYAIKKFKTEREGVEHYTGISQSACREMSLCRELDNNHLTKLVEIFLEKKSIYMVSEFA 265
+ AIKK K + E + RE+ ++L++ ++ KL E+ E +Y + E+
Sbjct: 28 ELIAIKKMKRKFYSWEECMNL-----REVKSLKKLNHANVVKLKEVIRENDHLYFIFEYM 82
Query: 266 EHDLLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGC 325
+ +L Q+I +L P +++IM+QIL G++++H++ HRDLKP N++
Sbjct: 83 KENLYQLIK----ERNKLFPESAIRNIMYQILQGLAFIHKHGFFHRDLKPENLLCMGPEL 138
Query: 326 VKIGDLGLARKFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELI 385
VKI D GLAR+ + + YT + T WYRAPE++L + +Y+ ID+WAVGCI AE+
Sbjct: 139 VKIADFGLAREIRS--KPPYTD--YVSTRWYRAPEVLLRSTNYSSPIDVWAVGCIMAEVY 194
Query: 386 GLRPIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPKYR 445
LRP+F G S+ +F KI +V+G+P W PE QL+ +R
Sbjct: 195 TLRPLFPG-----ASEIDTIF------KICQVLGTPKKTDW------PEGYQLSSAMNFR 237
Query: 446 DNLTAWYQTAGGKDKT--------ALDILYRLLQYDPIKRIDAIDALDHVYFTNGDP 494
W Q KT A+ +L +LQ+DP KR A AL + YF G P
Sbjct: 238 -----WPQCVPNNLKTLIPNASSEAVQLLRDMLQWDPKKRPTASQALRYPYFQVGHP 289
>Hs7706549 [D] KOG0600 Cdc2-related protein kinase
Length = 1490
Score = 147 bits (370), Expect = 6e-35
Identities = 91/294 (30%), Positives = 145/294 (48%), Gaps = 44/294 (14%)
Query: 206 QFYAIKKFKTEREGVEHYTGISQSACREMSLCRELDNNHLTKLVEIFLEKK--------- 256
+ A+KK + + E G +A RE+ + R+L + + + EI +K+
Sbjct: 751 ELVALKKVRLDNEK----EGFPITAIREIKILRQLIHRSVVNMKEIVTDKQDALDFKKDK 806
Query: 257 -SIYMVSEFAEHDLLQI-----IHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILH 310
+ Y+V E+ +HDL+ + +HF +KS M Q+++G+ Y H+ LH
Sbjct: 807 GAFYLVFEYMDHDLMGLLESGLVHFSEDH---------IKSFMKQLMEGLEYCHKKNFLH 857
Query: 311 RDLKPANIMVTVDGCVKIGDLGLARKFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTP 370
RD+K +NI++ G +K+ D GLAR +N+ YT ++T+WYR PEL+LG YTP
Sbjct: 858 RDIKCSNILLNNSGQIKLADFGLARLYNSEESRPYTNK--VITLWYRPPELLLGEERYTP 915
Query: 371 AIDLWAVGCIFAELIGLRPIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHKIWPNID 430
AID+W+ GCI EL +PIF+ + Q + I + GSP +WP++
Sbjct: 916 AIDVWSCGCILGELFTKKPIFQAN-----------LELAQLELISRLCGSPCPAVWPDVI 964
Query: 431 SYPEYLQLAKMPKYRDNLTAWYQTAGGKDKTALDILYRLLQYDPIKRIDAIDAL 484
P + + +YR L + ALD+L +L DP KR A L
Sbjct: 965 KLPYFNTMKPKKQYRRRLREEFSFI---PSAALDLLDHMLTLDPSKRCTAEQTL 1015
>SPBC32H8.10 [D] KOG0600 Cdc2-related protein kinase
Length = 591
Score = 146 bits (369), Expect = 8e-35
Identities = 112/331 (33%), Positives = 165/331 (49%), Gaps = 54/331 (16%)
Query: 208 YAIKKF--KTEREGVEHYTGISQSACREMSLCRELDNNHLTKLVEIFL---EKK-----S 257
YA+K+ TE+EG +A RE+ + + + + ++ L ++ + +KK S
Sbjct: 62 YALKRILMHTEKEG------FPITAIREIKILKSIKHENIIPLSDMTVVRADKKHRRRGS 115
Query: 258 IYMVSEFAEHDLLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPAN 317
IYMV+ + +HDL ++ +P + P+ +K M Q+ G YLH ILHRDLK AN
Sbjct: 116 IYMVTPYMDHDLSGLLE---NPSVKFTEPQ-IKCYMKQLFAGTKYLHDQLILHRDLKAAN 171
Query: 318 IMVTVDGCVKIGDLGLAR-----KFNNMVQTL-------YTGDKVIVTIWYRAPELILGA 365
+++ G +KI D GLAR + N L YTG +VT WYR+PEL+LG
Sbjct: 172 LLIDNHGILKIADFGLARVITEESYANKNPGLPPPNRREYTG--CVVTRWYRSPELLLGE 229
Query: 366 RHYTPAIDLWAVGCIFAELIGLRPIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHKI 425
R YT AID+W+VGCI AE+ RPI +G +Q KI + GSP
Sbjct: 230 RRYTTAIDMWSVGCIMAEMYKGRPILQGSS-----------DLDQLDKIFRLCGSPTQAT 278
Query: 426 WPNIDSYPEYLQLAKMPKYRDNLTAWYQTAGGKDKTALDILYRLLQYDPIKRIDAIDALD 485
PN + P + P + L + T GK+ T+L +L +P +R+ A AL+
Sbjct: 279 MPNWEKLPGCEGVRSFPSHPRTLETAFFTF-GKEMTSL--CGAILTLNPDERLSASMALE 335
Query: 486 HVYFTNGDPPVCENVFE----GLNYKYPPRR 512
H YFT PP N E +++Y RR
Sbjct: 336 HEYFTT--PPYPANPSELQSYSASHEYDKRR 364
>Hs21040235 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 384
Score = 145 bits (366), Expect = 2e-34
Identities = 89/267 (33%), Positives = 144/267 (53%), Gaps = 20/267 (7%)
Query: 225 GISQSACREMSLCRELDNNHLTKLVEIFLEKKSIYMVSEFAEHDLLQIIHFHSHPEKRLI 284
G+ +A RE SL + L + ++ L +I K+++ V E+ DL Q + HP +
Sbjct: 90 GVPFTAIREASLLKGLKHANIVLLHDIIHTKETLTFVFEYMHTDLAQ--YMSQHPGG--L 145
Query: 285 PPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGCVKIGDLGLARKFNNMVQTL 344
P ++ M+Q+L G++Y+H +LHRDLKP N++++ G +K+ D GLAR + QT
Sbjct: 146 HPHNVRLFMFQLLRGLAYIHHQHVLHRDLKPQNLLISHLGELKLADFGLARAKSIPSQT- 204
Query: 345 YTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELIGLRPIFKGEEAKMESKKSV 404
Y+ + +VT+WYR P+ +LGA Y+ +D+W GCIF E+ +P+F G +E
Sbjct: 205 YSSE--VVTLWYRPPDALLGATEYSSELDIWGAGCIFIEMFQGQPLFPGVSNILE----- 257
Query: 405 LFQANQFQKILEVMGSPDHKIWPNIDSYPEY-LQLAKMPKYRDNLTAWYQTAGGKDKTAL 463
Q +KI EV+G P WP + P Y + +P R W + G+ A
Sbjct: 258 -----QLEKIWEVLGVPTEDTWPGVSKLPNYNPEWFPLPTPRSLHVVWNRL--GRVPEAE 310
Query: 464 DILYRLLQYDPIKRIDAIDALDHVYFT 490
D+ ++L+ P R+ A +AL H YF+
Sbjct: 311 DLASQMLKGFPRDRVSAQEALVHDYFS 337
>CE26422 [D] KOG0600 Cdc2-related protein kinase
Length = 684
Score = 145 bits (366), Expect = 2e-34
Identities = 95/296 (32%), Positives = 159/296 (53%), Gaps = 49/296 (16%)
Query: 209 AIKKFKTEREGVEHYTGISQSACREMSLCRELDNNHLTKLVEIFLE----------KKSI 258
A+K+ + E E G +A RE+ + R+L + ++ +L++I ++ + +
Sbjct: 338 ALKRVRLENEK----EGFPITAIREIKILRQLHHKNIVRLMDIVIDDISMDELKRTRANF 393
Query: 259 YMVSEFAEHDLLQIIHFHSHPEKRLIP--PRMLKSIMWQILDGVSYLHQNWILHRDLKPA 316
Y+V E+ +HDL+ ++ K L+ + S+ Q+L+G++Y+H LHRD+K +
Sbjct: 394 YLVFEYVDHDLIGLLE-----SKELVDFNKDQICSLFKQLLEGLAYIHNTGFLHRDIKCS 448
Query: 317 NIMVTVDGCVKIGDLGLARKFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWA 376
NI+V G +KI DLGLAR + + LYT ++T+WYR PEL+LG Y PAID+W+
Sbjct: 449 NILVNNKGELKIADLGLARLWEKESR-LYTNR--VITLWYRPPELLLGDERYGPAIDVWS 505
Query: 377 VGCIFAELIGLRPIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEYL 436
GC+ EL +P+F G + Q + I +V GS PN+D++PE
Sbjct: 506 TGCMLGELFTRKPLFNGNN-----------EFGQLELISKVCGS------PNVDNWPELT 548
Query: 437 QLAKMPKYRDNLTAWYQTAGGKD------KTALDILYRLLQYDPIKRIDAIDALDH 486
+L +R T YQ ++ + A+D+L ++L +P KRI A +AL+H
Sbjct: 549 ELVGWNTFRMKRT--YQRRIREEFEHIMPREAVDLLDKMLTLNPEKRISAKEALNH 602
>At1g10210 [T] KOG0660 Mitogen-activated protein kinase
Length = 370
Score = 145 bits (366), Expect = 2e-34
Identities = 93/274 (33%), Positives = 145/274 (51%), Gaps = 31/274 (11%)
Query: 232 REMSLCRELDNNHLTKLVEIFL-----EKKSIYMVSEFAEHDLLQIIHFHSHPEKRLIPP 286
RE+ L R L + ++ L ++ + K +Y+V E + DL QII +++
Sbjct: 78 RELKLLRHLRHENVIALKDVMMPIHKMSFKDVYLVYELMDTDLHQIIK-----SSQVLSN 132
Query: 287 RMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGCVKIGDLGLARKFNNMVQTLYT 346
+ ++Q+L G+ Y+H ILHRDLKP N++V + +KI D GLAR N Q +
Sbjct: 133 DHCQYFLFQLLRGLKYIHSANILHRDLKPGNLLVNANCDLKICDFGLARASNTKGQFM-- 190
Query: 347 GDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELIGLRPIFKGEEAKMESKKSVLF 406
+ +VT WYRAPEL+L +Y +ID+W+VGCIFAEL+G +PIF+G E + K V
Sbjct: 191 -TEYVVTRWYRAPELLLCCDNYGTSIDVWSVGCIFAELLGRKPIFQGTECLNQLKLIVNI 249
Query: 407 QANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPKYRDNLTAWYQTAGGKDKTALDIL 466
+Q ++ LE + +P K + Y + L+++ G A+D+L
Sbjct: 250 LGSQREEDLEFIDNPKAKRYIRSLPYSPGMSLSRL-------------YPGAHVLAIDLL 296
Query: 467 YRLLQYDPIKRIDAIDALDHVYFT-----NGDPP 495
++L +DP KRI +AL H Y N +PP
Sbjct: 297 QKMLVFDPSKRISVSEALQHPYMAPLYDPNANPP 330
>YHR030c [T] KOG0660 Mitogen-activated protein kinase
Length = 484
Score = 144 bits (364), Expect = 3e-34
Identities = 102/294 (34%), Positives = 154/294 (51%), Gaps = 36/294 (12%)
Query: 224 TGISQSACREMSLCREL-DNNHLTKLVE---IFLEKKSI---YMVSEFAEHDLLQIIHFH 276
T + + + RE+ L R + ++T L + +F SI Y+ E E D+ QII
Sbjct: 63 TLLCKRSLRELKLLRHFRGHKNITCLYDMDIVFYPDGSINGLYLYEELMECDMHQIIK-- 120
Query: 277 SHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGCVKIGDLGLARK 336
+ + +S +QIL G+ Y+H +LHRDLKP N++V D +KI D GLAR
Sbjct: 121 ---SGQPLTDAHYQSFTYQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARG 177
Query: 337 FN-NMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELIGLRPIFKGEE 395
++ N V+ + + T WYRAPE++L + YT AID+W+ GCI AE +G +PIFKG++
Sbjct: 178 YSENPVENSQFLTEYVATRWYRAPEIMLSYQGYTKAIDVWSAGCILAEFLGGKPIFKGKD 237
Query: 396 AKMESKKSVLFQANQFQKILEVMGSPDHKIWPNIDS--YPEYL-QLAKMPKYRDNLTAWY 452
NQ +IL+V+G+P + I S +Y+ QL +PK +
Sbjct: 238 -----------YVNQLNQILQVLGTPPDETLRRIGSKNVQDYIHQLGFIPK-----VPFV 281
Query: 453 QTAGGKDKTALDILYRLLQYDPIKRIDAIDALDHVYFT----NGDPPVCENVFE 502
+ ALD+L ++L +DP KRI +AL+H Y + D PVC FE
Sbjct: 282 NLYPNANSQALDLLEQMLAFDPQKRITVDEALEHPYLSIWHDPADEPVCSEKFE 335
>Hs7705551 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 632
Score = 144 bits (364), Expect = 3e-34
Identities = 100/297 (33%), Positives = 153/297 (50%), Gaps = 43/297 (14%)
Query: 206 QFYAIKKFKTEREGVEHYTGISQSACREMSLCRELDNNHLTKLVEIFLEKKSIYMVSEFA 265
+ AIKK K + Y+ RE+ ++L++ ++ KL E+ E +Y + E+
Sbjct: 28 ELIAIKKMKRK-----FYSWEECMNQREVKSLKKLNHANVVKLKEVIRENDHLYFIFEYM 82
Query: 266 EHDLLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGC 325
+ +L Q+I +L P +++IM+QIL G++++H+ HRDLKP N++
Sbjct: 83 KENLYQLIK----ERNKLFPESAIRNIMYQILQGLAFIHKLGFFHRDLKPENLLCMGPEL 138
Query: 326 VKIGDLGLARKFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELI 385
VKI D GLAR+ + + YT + T WYRAPE++L + +Y+ ID+WAVGCI AE+
Sbjct: 139 VKIADFGLAREIRS--KPPYTD--YVSTRWYRAPEVLLRSTNYSSPIDVWAVGCIMAEVY 194
Query: 386 GLRPIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPKYR 445
LRP+F G S+ +F KI +V+G+P W PE QL+ +R
Sbjct: 195 TLRPLFPG-----ASEIDTIF------KICQVLGTPKKTDW------PEGYQLSSAMNFR 237
Query: 446 DNLTAWYQTAGGKDKT--------ALDILYRLLQYDPIKRIDAIDALDHVYFTNGDP 494
W Q KT A+ +L +LQ+DP KR A AL + YF G P
Sbjct: 238 -----WPQCVPNNLKTLIPNASSEAVQLLRDMLQWDPKKRPTASQALRYPYFQVGHP 289
>7297578 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 822
Score = 144 bits (364), Expect = 3e-34
Identities = 103/321 (32%), Positives = 160/321 (49%), Gaps = 36/321 (11%)
Query: 209 AIKKFKTEREGVEHYTGISQSACREMSLCRELDNNHLTKLVEIFLEKKSIYMVSEFAEHD 268
AIK+ K + +Y+ RE+ ++L + ++ KL E+ E ++Y V E+ + +
Sbjct: 31 AIKRMKRK-----YYSWEEAMNLREVKSLKKLSHPNIVKLKEVIRENDTLYFVFEYMKEN 85
Query: 269 LLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGCVKI 328
L Q+I +P LKSI++Q+L G++++H++ HRDLKP N++ + +KI
Sbjct: 86 LYQMIK----DRDTHLPEPELKSILFQVLTGLAFMHRHGFFHRDLKPENLLCSGPDLIKI 141
Query: 329 GDLGLARKFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELIGLR 388
D GLAR+ + + +T + T WYRAPE++L + +Y IDLWA+GCI AEL R
Sbjct: 142 ADFGLAREIRS--RPPFTD--YVSTRWYRAPEVLLHSTNYGSTIDLWAMGCIMAELYTFR 197
Query: 389 PIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMP--KYRD 446
P+F G + +Q KI V+G+PD WP D Y +LA M +Y D
Sbjct: 198 PLFPGSS-----------EVDQLFKICSVLGTPDKDDWP--DGY----RLASMIHFRYPD 240
Query: 447 NLTAWYQTAGGK-DKTALDILYRLLQYDPIKRIDAIDALDHVYF---TNGDPPVCENVFE 502
+ + + + LD+L +L YDP KR A +L + YF P
Sbjct: 241 CIKVPLSSVVSRCSQNGLDLLEDMLAYDPDKRPTAQQSLKYPYFHALKRISPTAATKANV 300
Query: 503 GLNYKYPPRRIHTNDNDITNV 523
LN KY H + NV
Sbjct: 301 RLNSKYAASNGHPVQSVSNNV 321
>Hs20986501 [T] KOG0660 Mitogen-activated protein kinase
Length = 816
Score = 144 bits (362), Expect = 5e-34
Identities = 96/308 (31%), Positives = 156/308 (50%), Gaps = 33/308 (10%)
Query: 206 QFYAIKKFKTEREGVEHYTGISQSACREMSLCRELDNNHLTKLVEI------FLEKKSIY 259
Q AIKK + V + ++ RE+ + + ++++ + +I + E KS+Y
Sbjct: 79 QQVAIKKIPNAFDVVTN----AKRTLRELKILKHFKHDNIIAIKDILRPTVPYGEFKSVY 134
Query: 260 MVSEFAEHDLLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIM 319
+V + E DL QIIH S P + ++ ++Q+L G+ Y+H ++HRDLKP+N++
Sbjct: 135 VVLDLMESDLHQIIH-SSQP----LTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLL 189
Query: 320 VTVDGCVKIGDLGLARKF-NNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVG 378
V + +KIGD G+AR + + Y + + T WYRAPEL+L YT AIDLW+VG
Sbjct: 190 VNENCELKIGDFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVG 249
Query: 379 CIFAELIGLRPIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQL 438
CIF E++ R +F G+ +Q Q I+ V+G+P + + + +
Sbjct: 250 CIFGEMLARRQLFPGKN-----------YVHQLQLIMMVLGTPSPAVIQAVGAERVRAYI 298
Query: 439 AKMPKYRDNLTAWYQTAGGKDKTALDILYRLLQYDPIKRIDAIDALDH----VYFTNGDP 494
+P + W G D+ AL +L R+L+++P RI A AL H Y D
Sbjct: 299 QSLPPRQP--VPWETVYPGADRQALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDE 356
Query: 495 PVCENVFE 502
P C F+
Sbjct: 357 PDCAPPFD 364
>Hs20986497 [T] KOG0660 Mitogen-activated protein kinase
Length = 816
Score = 144 bits (362), Expect = 5e-34
Identities = 96/308 (31%), Positives = 156/308 (50%), Gaps = 33/308 (10%)
Query: 206 QFYAIKKFKTEREGVEHYTGISQSACREMSLCRELDNNHLTKLVEI------FLEKKSIY 259
Q AIKK + V + ++ RE+ + + ++++ + +I + E KS+Y
Sbjct: 79 QQVAIKKIPNAFDVVTN----AKRTLRELKILKHFKHDNIIAIKDILRPTVPYGEFKSVY 134
Query: 260 MVSEFAEHDLLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIM 319
+V + E DL QIIH S P + ++ ++Q+L G+ Y+H ++HRDLKP+N++
Sbjct: 135 VVLDLMESDLHQIIH-SSQP----LTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLL 189
Query: 320 VTVDGCVKIGDLGLARKF-NNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVG 378
V + +KIGD G+AR + + Y + + T WYRAPEL+L YT AIDLW+VG
Sbjct: 190 VNENCELKIGDFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVG 249
Query: 379 CIFAELIGLRPIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQL 438
CIF E++ R +F G+ +Q Q I+ V+G+P + + + +
Sbjct: 250 CIFGEMLARRQLFPGKN-----------YVHQLQLIMMVLGTPSPAVIQAVGAERVRAYI 298
Query: 439 AKMPKYRDNLTAWYQTAGGKDKTALDILYRLLQYDPIKRIDAIDALDH----VYFTNGDP 494
+P + W G D+ AL +L R+L+++P RI A AL H Y D
Sbjct: 299 QSLPPRQP--VPWETVYPGADRQALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDE 356
Query: 495 PVCENVFE 502
P C F+
Sbjct: 357 PDCAPPFD 364
>CE26988 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 308
Score = 143 bits (361), Expect = 6e-34
Identities = 94/282 (33%), Positives = 145/282 (51%), Gaps = 47/282 (16%)
Query: 209 AIKKFKT-EREGVEHYTGISQSACREMSLCRELDNNHLTKLVEIFLEKKSIYMVSEFAEH 267
AIKK K RE E GI+++A RE+ L +E+ ++++ L ++ + SI +V +F +
Sbjct: 32 AIKKIKLGSRE--EAKDGINRTAIREIKLLKEIHHDNIIGLRDVIGHRTSIQLVFDFMDT 89
Query: 268 DLLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGCVK 327
DL +I ++ ++ P +K+I Q+L G+ +LH +WILHRDLKP N+++ G V
Sbjct: 90 DLEHVIK----DKEIILMPAHIKNITMQMLLGLEFLHVHWILHRDLKPNNLLMNKMGRV- 144
Query: 328 IGDLGLARKFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELIGL 387
VT WYRAPEL+ GAR Y ID+W+VGCI AEL+
Sbjct: 145 ------------------------VTRWYRAPELLFGARSYGVGIDIWSVGCIIAELLLR 180
Query: 388 RPIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPKYRDN 447
PIF GE +Q KI ++G P + WPN+ Y+ + +Y
Sbjct: 181 NPIFPGES-----------DIDQLVKIFNILGCPTPETWPNMTEMNSYVIIKPQTEYM-- 227
Query: 448 LTAWYQTAGGKDKTALDILYRLLQYDPIKRIDAIDALDHVYF 489
+Y +A +D LD++ + +DPIKR+ +L YF
Sbjct: 228 ALNYYFSAAPQD--LLDLMAGMWTFDPIKRLTCTQSLQMEYF 267
>CE12408 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 527
Score = 142 bits (359), Expect = 1e-33
Identities = 90/284 (31%), Positives = 149/284 (51%), Gaps = 33/284 (11%)
Query: 209 AIKKFKTEREGVEHYTGISQSACREMSLCRELDNNHLTKLVEIFLEKKSIYMVSEFAEHD 268
AIK+ K + Y+ + RE+ ++L++ ++ KL E+ E +Y V EF + +
Sbjct: 72 AIKRMKKK-----FYSWEEAMSLREVKSLKKLNHPNIIKLREVIRENDILYFVFEFMQEN 126
Query: 269 LLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGCVKI 328
L +++ R P ++++I++Q+L G++++H+N HRD+KP NIM VKI
Sbjct: 127 LYELMK----DRDRYFPESVIRNIIYQVLQGLAFMHKNGFFHRDMKPENIMCNGTELVKI 182
Query: 329 GDLGLARKFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELIGLR 388
D GLAR+ + + YT + T WYRAPE++L + Y ID+WA+GCI AEL LR
Sbjct: 183 ADFGLAREIRS--KPPYT--DYVSTRWYRAPEILLRSTSYNSPIDMWALGCIMAELYILR 238
Query: 389 PIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPKYRDN- 447
P+F G + +Q KI+ ++G+ PN D +PE QLA +R
Sbjct: 239 PLFPGTS-----------EMDQLFKIISILGT------PNKDEWPEGYQLASAMNFRFQQ 281
Query: 448 --LTAWYQTAGGKDKTALDILYRLLQYDPIKRIDAIDALDHVYF 489
T Q K + ++ ++ ++P KR +A +L + YF
Sbjct: 282 VVATPMEQVVNTISKEGMKLMMDMMLWNPEKRPNANQSLRYKYF 325
>At2g18170 [T] KOG0660 Mitogen-activated protein kinase
Length = 368
Score = 142 bits (357), Expect = 2e-33
Identities = 95/263 (36%), Positives = 139/263 (52%), Gaps = 28/263 (10%)
Query: 232 REMSLCRELDNNHLTKLVEIFLEK-----KSIYMVSEFAEHDLLQIIHFHSHPEKRLIPP 286
RE+ L R + + ++ L ++ L K +Y+V E + DL QII + +
Sbjct: 78 RELKLLRHVRHENVIALKDVMLPANRSSFKDVYLVYELMDTDLHQIIK-----SSQSLSD 132
Query: 287 RMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGCVKIGDLGLARKFNNMVQTLYT 346
K ++Q+L G+ YLH ILHRDLKP N++V + +KI D GLAR Q +
Sbjct: 133 DHCKYFLFQLLRGLKYLHSANILHRDLKPGNLLVNANCDLKICDFGLARTSQGNEQFM-- 190
Query: 347 GDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELIGLRPIFKGEEAKMESKKSVLF 406
+ +VT WYRAPEL+L +Y +ID+W+VGCIFAE++G +PIF G E
Sbjct: 191 -TEYVVTRWYRAPELLLCCDNYGTSIDVWSVGCIFAEILGRKPIFPGTEC---------- 239
Query: 407 QANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPKYR-DNLTAWYQTAGGKDKTALDI 465
NQ + I+ V+GS ID+ + +P R +L+ Y A + A+D+
Sbjct: 240 -LNQLKLIINVVGSQQESDIRFIDNPKARRFIKSLPYSRGTHLSNLYPQA---NPLAIDL 295
Query: 466 LYRLLQYDPIKRIDAIDALDHVY 488
L R+L +DP KRI DAL H Y
Sbjct: 296 LQRMLVFDPTKRISVTDALLHPY 318
>At1g59580 [T] KOG0660 Mitogen-activated protein kinase
Length = 376
Score = 142 bits (357), Expect = 2e-33
Identities = 90/262 (34%), Positives = 143/262 (54%), Gaps = 26/262 (9%)
Query: 232 REMSLCRELDNNHLTKLVEIFLEK-----KSIYMVSEFAEHDLLQIIHFHSHPEKRLIPP 286
RE+ L R L + ++ L ++ + K +Y+V E + DL QII +++
Sbjct: 78 RELKLLRHLRHENVVALKDVMMANHKRSFKDVYLVYELMDTDLHQIIK-----SSQVLSN 132
Query: 287 RMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGCVKIGDLGLARKFNNMVQTLYT 346
+ ++Q+L G+ Y+H ILHRDLKP N++V + +KI D GLAR N Q +
Sbjct: 133 DHCQYFLFQLLRGLKYIHSANILHRDLKPGNLLVNANCDLKICDFGLARTSNTKGQFM-- 190
Query: 347 GDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELIGLRPIFKGEEAKMESKKSVLF 406
+ +VT WYRAPEL+L +Y +ID+W+VGCIFAEL+G +P+F G E + K +
Sbjct: 191 -TEYVVTRWYRAPELLLCCDNYGTSIDVWSVGCIFAELLGRKPVFPGTECLNQIKLIINI 249
Query: 407 QANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPKYRDNLTAWYQTAGGKDKTALDIL 466
+Q ++ LE + +P K + I+S P Y + ++ + G + A+D+L
Sbjct: 250 LGSQREEDLEFIDNPKAKRY--IESLP----------YSPGI-SFSRLYPGANVLAIDLL 296
Query: 467 YRLLQYDPIKRIDAIDALDHVY 488
++L DP KRI +AL H Y
Sbjct: 297 QKMLVLDPSKRISVTEALQHPY 318
>7292375 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 509
Score = 142 bits (357), Expect = 2e-33
Identities = 89/288 (30%), Positives = 149/288 (50%), Gaps = 31/288 (10%)
Query: 206 QFYAIKKFKTEREGVEHYTGISQSACREMSLCRELDNNHLTKLVEIFLEKKSIYMVSEFA 265
Q A+K+ + + E +T I RE SL +EL ++++ L +I ++++ V E+
Sbjct: 216 QRVALKEIRLQEEEGAPFTAI-----REASLLKELKHSNIVTLHDIVHTRETLTFVFEYV 270
Query: 266 EHDLLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGC 325
DL Q + HP + R ++ ++Q+L G+SY H+ +LHRD+KP N++++ G
Sbjct: 271 NTDLSQ--YMEKHPGG--LDHRNVRLFLFQLLRGLSYCHKRRVLHRDVKPQNLLISDCGE 326
Query: 326 VKIGDLGLARKFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELI 385
+K+ D GLAR + +T +VT+WYR P+++LG+ Y+ ++D+W VGCIF E++
Sbjct: 327 LKLADFGLARAKS---VPSHTYSHEVVTLWYRPPDVLLGSTEYSTSLDMWGVGCIFVEMV 383
Query: 386 GLRPIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEY----LQLAKM 441
P F G + +Q KI +++G+P WP + +P Y L +
Sbjct: 384 TGMPTFPG----------IRDTYDQLDKIFKLLGTPTEDTWPGVTHFPGYKPHKLGFYRP 433
Query: 442 PKYRDNLTAWYQTAGGKDKTALDILYRLLQYDPIKRIDAIDALDHVYF 489
K N Y G+ I LQ +P +R+ A DAL H YF
Sbjct: 434 RKLGHNFPRLYDIIEGE-----TIANGFLQLNPEQRLGADDALQHPYF 476
>Hs11496279 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 623
Score = 140 bits (354), Expect = 4e-33
Identities = 89/267 (33%), Positives = 141/267 (52%), Gaps = 34/267 (12%)
Query: 232 REMSLCRELDNNHLTKLVEIFLEKKSIYMVSEFAEHDLLQIIHFHSHPEKRLIPPRMLKS 291
RE+ ++L++ ++ KL E+ E +Y + E+ + +L Q++ +L P ++++
Sbjct: 49 REVKSLKKLNHANVIKLKEVIRENDHLYFIFEYMKENLYQLMK----DRNKLFPESVIRN 104
Query: 292 IMWQILDGVSYLHQNWILHRDLKPANIMVTVDGCVKIGDLGLARKFNNMVQTLYTGDKVI 351
IM+QIL G++++H++ HRD+KP N++ VKI D GLAR+ + Q YT +
Sbjct: 105 IMYQILQGLAFIHKHGFFHRDMKPENLLCMGPELVKIADFGLARELRS--QPPYT--DYV 160
Query: 352 VTIWYRAPELILGARHYTPAIDLWAVGCIFAELIGLRPIFKGEEAKMESKKSVLFQANQF 411
T WYRAPE++L + Y+ ID+WAVG I AEL LRP+F G + ++
Sbjct: 161 STRWYRAPEVLLRSSVYSSPIDVWAVGSIMAELYMLRPLFPGTS-----------EVDEI 209
Query: 412 QKILEVMGSPDHKIWPNIDSYPEYLQLAKMPKYR------DNLTAWYQTAGGKDKTALDI 465
KI +V+G+P W PE QLA +R NL A + A+ +
Sbjct: 210 FKICQVLGTPKKSDW------PEGYQLASSMNFRFPQCVPINLKTLIPNASNE---AIQL 260
Query: 466 LYRLLQYDPIKRIDAIDALDHVYFTNG 492
+ +L +DP KR A AL H YF G
Sbjct: 261 MTEMLNWDPKKRPTASQALKHPYFQVG 287
>At4g36450 [T] KOG0660 Mitogen-activated protein kinase
Length = 361
Score = 140 bits (354), Expect = 4e-33
Identities = 95/277 (34%), Positives = 141/277 (50%), Gaps = 32/277 (11%)
Query: 232 REMSLCRELDNNHLTKLVEIFLEK-----KSIYMVSEFAEHDLLQIIHFHSHPEKRLIPP 286
RE+ L R + + ++ L ++ L + +Y+V E + DL QII + +
Sbjct: 78 RELKLLRHVRHENVISLKDVMLPTHRYSFRDVYLVYELMDSDLNQIIK-----SSQSLSD 132
Query: 287 RMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGCVKIGDLGLARKFNNMVQTLYT 346
K ++Q+L G+ YLH ILHRDLKP N++V + +KI D GLAR + +
Sbjct: 133 DHCKYFLFQLLRGLKYLHSANILHRDLKPGNLLVNANCDLKICDFGLARTYEQFMT---- 188
Query: 347 GDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELIGLRPIFKGEEAKMESKKSVLF 406
+ +VT WYRAPEL+L +Y +ID+W+VGCIFAE++G +PIF G E
Sbjct: 189 --EYVVTRWYRAPELLLCCDNYGTSIDVWSVGCIFAEILGRKPIFPGTEC---------- 236
Query: 407 QANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPKYRDNLTAWYQTAGGKDKTALDIL 466
NQ + I+ V+GS ID+ + +P + T + + A+D+L
Sbjct: 237 -LNQLKLIINVVGSQQDWDLQFIDNQKARRFIKSLPFSKG--THFSHIYPHANPLAIDLL 293
Query: 467 YRLLQYDPIKRIDAIDALDHVYFTNGDPPVC---ENV 500
R+L +DP KRI DAL H Y P C ENV
Sbjct: 294 QRMLVFDPTKRISVSDALLHPYMEGLLEPECNPSENV 330
>CE29612 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 426
Score = 140 bits (353), Expect = 5e-33
Identities = 88/285 (30%), Positives = 153/285 (52%), Gaps = 21/285 (7%)
Query: 209 AIKKFKTEREGVEHYTGISQSACREMSLCRELDNNHLTKLVEIFLEKKSIYMVSEFAEHD 268
A+K+ K ++ G+ +A RE SL R L + ++ L +IF + + V E+ + D
Sbjct: 135 ALKEIK-----LQFQEGLPFTAIREASLLRNLRHANIVSLHDIFYQHHQLTFVFEYMKMD 189
Query: 269 LLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGCVKI 328
L + + + + + +K +++Q+L G+ + H+ ILHRDLKP N+++ DG +K+
Sbjct: 190 LSKYLEQNVYGLDSID----IKLLLFQLLRGLDFCHRKKILHRDLKPQNLLLDEDGVLKL 245
Query: 329 GDLGLARKFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELIGLR 388
D GLAR ++ Y+ + +VT+WYR P++++G+ Y+ ++D+W VGCIFAE+
Sbjct: 246 ADFGLARA-KSVPSRTYSHE--VVTLWYRPPDVLMGSTDYSTSLDMWGVGCIFAEICTGA 302
Query: 389 PIFKG-EEAKMESKKSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPKYRD- 446
+F G +++ K +Q I + G+PD K WP + + P Y P+YR+
Sbjct: 303 ALFPGSKDSHYPGTK------DQLDMIFSIRGTPDEKKWPEVKTLPGYTP-ELFPRYREL 355
Query: 447 NLTAWYQTAGGKDKTALDILYRLLQYDPIKRIDAIDALDHVYFTN 491
+ A KT ++L LLQ P R+ A A+ H YF +
Sbjct: 356 SFIAVNPMFTKILKTGQELLGMLLQLRPESRVSAASAMLHPYFAS 400
>CE24971 [T] KOG0660 Mitogen-activated protein kinase
Length = 444
Score = 140 bits (353), Expect = 5e-33
Identities = 104/307 (33%), Positives = 151/307 (48%), Gaps = 43/307 (14%)
Query: 209 AIKKFKTEREGVEHYTGISQSACREMSLCRELDNNHLTKLVEIFLEK-----KSIYMVSE 263
AIKK EH T Q RE+ + + ++ + EI + K IY+V
Sbjct: 123 AIKKISP----FEHQT-FCQRTLREIKILNRFKHENIINIQEIIRSETVDSLKDIYIVQC 177
Query: 264 FAEHDLLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVD 323
E DL +++ + ++QIL G+ Y+H +LHRDLKP+N+++
Sbjct: 178 LMETDLYKLLKTQKLSNDHVC------YFLYQILRGLKYIHSANVLHRDLKPSNLLLNTT 231
Query: 324 GCVKIGDLGLARKFNNMVQTLYTG--DKVIVTIWYRAPELILGARHYTPAIDLWAVGCIF 381
+KI D GLAR + QT +TG + + T WYRAPE++L ++ YT +ID+W+VGCI
Sbjct: 232 CDLKICDFGLARVTDP--QTDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDVWSVGCIL 289
Query: 382 AELIGLRPIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHKIWPNI--DSYPEYL-QL 438
AE++ RP+F G+ +Q IL V+GSP + I D YL L
Sbjct: 290 AEMLSNRPLFPGKH-----------YLDQLNLILAVVGSPSNADLQCIINDKARSYLISL 338
Query: 439 AKMPKYRDNLTAWYQTAGGKDKTALDILYRLLQYDPIKRIDAIDALDH----VYFTNGDP 494
PK W + G D ALD+L ++L ++P RID AL H Y+ GD
Sbjct: 339 PHKPK-----QPWARLYPGADPRALDLLDKMLTFNPHNRIDIEQALAHPYLEQYYDPGDE 393
Query: 495 PVCENVF 501
PVCE F
Sbjct: 394 PVCEEPF 400
>CE01583 [T] KOG0660 Mitogen-activated protein kinase
Length = 376
Score = 140 bits (353), Expect = 5e-33
Identities = 104/307 (33%), Positives = 151/307 (48%), Gaps = 43/307 (14%)
Query: 209 AIKKFKTEREGVEHYTGISQSACREMSLCRELDNNHLTKLVEIFLEK-----KSIYMVSE 263
AIKK EH T Q RE+ + + ++ + EI + K IY+V
Sbjct: 55 AIKKISP----FEHQT-FCQRTLREIKILNRFKHENIINIQEIIRSETVDSLKDIYIVQC 109
Query: 264 FAEHDLLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVD 323
E DL +++ + ++QIL G+ Y+H +LHRDLKP+N+++
Sbjct: 110 LMETDLYKLLKTQKLSNDHVC------YFLYQILRGLKYIHSANVLHRDLKPSNLLLNTT 163
Query: 324 GCVKIGDLGLARKFNNMVQTLYTG--DKVIVTIWYRAPELILGARHYTPAIDLWAVGCIF 381
+KI D GLAR + QT +TG + + T WYRAPE++L ++ YT +ID+W+VGCI
Sbjct: 164 CDLKICDFGLARVTDP--QTDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDVWSVGCIL 221
Query: 382 AELIGLRPIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHKIWPNI--DSYPEYL-QL 438
AE++ RP+F G+ +Q IL V+GSP + I D YL L
Sbjct: 222 AEMLSNRPLFPGKH-----------YLDQLNLILAVVGSPSNADLQCIINDKARSYLISL 270
Query: 439 AKMPKYRDNLTAWYQTAGGKDKTALDILYRLLQYDPIKRIDAIDALDH----VYFTNGDP 494
PK W + G D ALD+L ++L ++P RID AL H Y+ GD
Sbjct: 271 PHKPK-----QPWARLYPGADPRALDLLDKMLTFNPHNRIDIEQALAHPYLEQYYDPGDE 325
Query: 495 PVCENVF 501
PVCE F
Sbjct: 326 PVCEEPF 332
>At3g59790 [T] KOG0660 Mitogen-activated protein kinase
Length = 393
Score = 140 bits (352), Expect = 7e-33
Identities = 92/282 (32%), Positives = 153/282 (53%), Gaps = 38/282 (13%)
Query: 232 REMSLCRELDNNHLTKLVEIFLEKK-----SIYMVSEFAEHDLLQIIHFHSHPEKRLIPP 286
RE+ L R D+ ++ + ++ L + +Y+V+E E DL + + ++ L
Sbjct: 106 REIKLLRHFDHENIVAIRDVILPPQRDSFEDVYIVNELMEFDLYRTLK----SDQELTKD 161
Query: 287 RMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGCVKIGDLGLARKF-NNMVQTLY 345
+ M+QIL G+ Y+H +LHRDLKP+N++++ +KI D GLAR + + T Y
Sbjct: 162 HGMY-FMYQILRGLKYIHSANVLHRDLKPSNLLLSTQCDLKICDFGLARATPESNLMTEY 220
Query: 346 TGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELIGLRPIFKGEEAKMESKKSVL 405
+VT WYRAPEL+LG+ YT AID+W+VGCIF E++ P+F G++
Sbjct: 221 -----VVTRWYRAPELLLGSSDYTAAIDVWSVGCIFMEIMNREPLFPGKD---------- 265
Query: 406 FQANQFQKILEVMGSPDHKIWPNIDSYPE-YL-QLAKMPKYRDNLTAWYQTAGGKDKTAL 463
Q NQ + +LE++G+P + ++ Y + Y+ QL +P R + T + A+
Sbjct: 266 -QVNQLRLLLELIGTPSEEELGSLSEYAKRYIRQLPTLP--RQSFTEKFPNV---PPLAI 319
Query: 464 DILYRLLQYDPIKRIDAIDALDHVYFTN----GDPPVCENVF 501
D++ ++L +DP +RI +AL H Y ++ D P C F
Sbjct: 320 DLVEKMLTFDPKQRISVKEALAHPYLSSFHDITDEPECSEPF 361
>Hs4502735 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 303
Score = 139 bits (351), Expect = 9e-33
Identities = 93/295 (31%), Positives = 151/295 (50%), Gaps = 34/295 (11%)
Query: 202 PSQIQFYAIKKFKTEREGVEHYTGISQSACREMSLCRELD---NNHLTKLVEIFLEKKS- 257
P F A+K + G G+ S RE++L R L+ + ++ +L+++ ++
Sbjct: 26 PHSGHFVALKSVRVPNGGGGG-GGLPISTVREVALLRRLEAFEHPNVVRLMDVCATSRTD 84
Query: 258 ----IYMVSEFAEHDLLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDL 313
+ +V E + DL + P +P +K +M Q L G+ +LH N I+HRDL
Sbjct: 85 REIKVTLVFEHVDQDLRTYLDKAPPPG---LPAETIKDLMRQFLRGLDFLHANCIVHRDL 141
Query: 314 KPANIMVTVDGCVKIGDLGLARKFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAID 373
KP NI+VT G VK+ D GLAR ++ + V+VT+WYRAPE++L + + TP +D
Sbjct: 142 KPENILVTSGGTVKLADFGLARIYSYQMAL----TPVVVTLWYRAPEVLLQSTYATP-VD 196
Query: 374 LWAVGCIFAELIGLRPIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHKIWPNIDSYP 433
+W+VGCIFAE+ +P+F G +A+Q KI +++G P WP S P
Sbjct: 197 MWSVGCIFAEMFRRKPLFCGNS-----------EADQLGKIFDLIGLPPEDDWPRDVSLP 245
Query: 434 EYLQLAKMPKYRDNLTAWYQTAGGKDKTALDILYRLLQYDPIKRIDAIDALDHVY 488
+ P+ ++ + +G + +L +L ++P KRI A AL H Y
Sbjct: 246 RGAFPPRGPRPVQSVVPEMEESGAQ------LLLEMLTFNPHKRISAFRALQHSY 294
>Hs16160923 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 472
Score = 139 bits (350), Expect = 1e-32
Identities = 86/270 (31%), Positives = 140/270 (51%), Gaps = 21/270 (7%)
Query: 220 VEHYTGISQSACREMSLCRELDNNHLTKLVEIFLEKKSIYMVSEFAEHDLLQIIHFHSHP 279
+EH G +A RE+SL + L + ++ L ++ +S+ +V E+ + DL Q + +
Sbjct: 175 LEHEEGAPCTAIREVSLLKNLKHANIVTLHDLIHTDRSLTLVFEYLDSDLKQYLDHCGN- 233
Query: 280 EKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGCVKIGDLGLARKFNN 339
L+ +K M+Q+L G++Y H ILHRDLKP N+++ G +K+ D GLAR +
Sbjct: 234 ---LMSMHNVKIFMFQLLRGLAYCHHRKILHRDLKPQNLLINERGELKLADFGLARAKSV 290
Query: 340 MVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELIGLRPIFKGEEAKME 399
+T Y+ + +VT+WYR P+++LG+ Y+ ID+W VGCI E+ RP+F G K E
Sbjct: 291 PTKT-YSNE--VVTLWYRPPDVLLGSTEYSTPIDMWGVGCIHYEMATGRPLFPGSTVKEE 347
Query: 400 SKKSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPKYRDNLTAWYQTAGGKD 459
I ++G+P + WP + ++ E+ + P Y A D
Sbjct: 348 -----------LHLIFRLLGTPTEETWPGVTAFSEF-RTYSFPCYLPQ--PLINHAPRLD 393
Query: 460 KTALDILYRLLQYDPIKRIDAIDALDHVYF 489
+ +L LL Y+ R+ A AL H YF
Sbjct: 394 TDGIHLLSSLLLYESKSRMSAEAALSHSYF 423
>YPR161c [D] KOG0600 Cdc2-related protein kinase
Length = 657
Score = 138 bits (348), Expect = 2e-32
Identities = 93/294 (31%), Positives = 150/294 (50%), Gaps = 42/294 (14%)
Query: 229 SACREMSLCRELDNNHLTKLVEIFLEK-------------KSIYMVSEFAEHDLLQIIHF 275
+A RE+++ + L++ ++ KL+E+ + KS YM+ + DL ++H
Sbjct: 103 TAQREITILKRLNHKNIIKLIEMVYDHSPDITNAASSNLHKSFYMILPYMVADLSGVLH- 161
Query: 276 HSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGCVKIGDLGLAR 335
+P L +K++M QIL+G++Y+H +HRD+K ANI++ +G +K+ D GLAR
Sbjct: 162 --NPRINL-EMCDIKNMMLQILEGLNYIHCAKFMHRDIKTANILIDHNGVLKLADFGLAR 218
Query: 336 KFNNMVQTL-YTGD--------KVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELIG 386
+ L Y G V+VT WYRAPEL+LG + YT A+D+W VGC+FAE
Sbjct: 219 LYYGCPPNLKYPGGAGSGAKYTSVVVTRWYRAPELVLGDKQYTTAVDIWGVGCVFAEFFE 278
Query: 387 LRPIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPKYRD 446
+PI +G+ +Q I +++G+P + W + YL A++
Sbjct: 279 KKPILQGKT-----------DIDQGHVIFKLLGTPTEEDW----AVARYLPGAELTTTNY 323
Query: 447 NLTAWYQTAGGKDKTALDILYRLLQYDPIKRIDAIDALDHVYFTNGDPPVCENV 500
T + +T LD L +LL DP KR+ A+ A H +F DP E +
Sbjct: 324 KPTLRERFGKYLSETGLDFLGQLLALDPYKRLTAMSAKHHPWFKE-DPLPSEKI 376
>At1g74330 [D] KOG0600 Cdc2-related protein kinase
Length = 445
Score = 138 bits (347), Expect = 3e-32
Identities = 92/290 (31%), Positives = 144/290 (48%), Gaps = 24/290 (8%)
Query: 232 REMSLCRELDNNHLTKLVEIFLEKKS--IYMVSEFAEHDLLQIIHFHSHPEKRLIPPRML 289
RE+ + R L++ ++ KL + K S I +V E+ EHDL ++ S P+ + P+ +
Sbjct: 167 REILILRRLNHPNIIKLEGLITSKLSCNIQLVFEYMEHDLTGLL---SSPDIKFTTPQ-I 222
Query: 290 KSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGCVKIGDLGLARKFNNMVQTLYTGDK 349
K M Q+L G+ + H ++HRD+K +N++++ +G +K+ D GLA N+
Sbjct: 223 KCYMKQLLSGLDHCHSRGVMHRDIKGSNLLLSNEGILKVADFGLANFSNSSGHKKKPLTS 282
Query: 350 VIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELIGLRPIFKGEEAKMESKKSVLFQAN 409
+VT+WYR PEL+LGA Y ++DLW+VGC+FAEL+ +PI +G +
Sbjct: 283 RVVTLWYRPPELLLGATDYGASVDLWSVGCVFAELLLGKPILRGRT-----------EVE 331
Query: 410 QFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPKYRDNLTAWYQTAGGKDKTALDILYRL 469
Q KI ++ GSP W P + Y L +T +T ++++ L
Sbjct: 332 QLHKIFKLCGSPPEDYWKK-SKLPHAMLFKPQQTYDSCLR---ETLKDLSETEINLIETL 387
Query: 470 LQYDPIKRIDAIDALDHVYFTNGDPPVCENVFEGLNYKYPPRRIHTNDND 519
L DP KR A AL YFT P C+ L P + I T D
Sbjct: 388 LSIDPHKRGTASSALVSQYFTT-KPFACDP--SSLPIYPPSKEIDTKHRD 434
>Hs4758652 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 358
Score = 137 bits (346), Expect = 4e-32
Identities = 90/289 (31%), Positives = 148/289 (51%), Gaps = 30/289 (10%)
Query: 206 QFYAIKKF-KTEREGVEHYTGISQSACREMSLCRELDNNHLTKLVEIFLEKKSIYMVSEF 264
Q AIKKF ++E + V I + A RE+ + ++L + +L L+E+F K+ +++V E+
Sbjct: 29 QIVAIKKFLESEDDPV-----IKKIALREIRMLKQLKHPNLVNLLEVFRRKRRLHLVFEY 83
Query: 265 AEHDLLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDG 324
+H +L + + +R +P ++KSI WQ L V++ H++ +HRD+KP NI++T
Sbjct: 84 CDHTVLHELDRY----QRGVPEHLVKSITWQTLQAVNFCHKHNCIHRDVKPENILITKHS 139
Query: 325 CVKIGDLGLARKFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAEL 384
+K+ D G AR YT + T WYR+PEL++G Y P +D+WA+GC+FAEL
Sbjct: 140 VIKLCDFGFARLLTGP-SDYYTD--YVATRWYRSPELLVGDTQYGPPVDVWAIGCVFAEL 196
Query: 385 IGLRPIFKGEEAKMESKKSVLFQANQFQKILEVMGS--PDHKIWPNIDSYPEYLQLAKMP 442
+ P++ G+ +Q I + +G P H+ + S +Y K+P
Sbjct: 197 LSGVPLWPGKS-----------DVDQLYLIRKTLGDLIPRHQ---QVFSTNQYFSGVKIP 242
Query: 443 KYRDNLTAWYQTAGGKDKTALDILYRLLQYDPIKRIDAIDALDHVYFTN 491
D + AL +L L DP +R+ L H YF N
Sbjct: 243 DPED-MEPLELKFPNISYPALGLLKGCLHMDPTERLTCEQLLHHPYFEN 290
>SPBC119.08 [T] KOG0660 Mitogen-activated protein kinase
Length = 422
Score = 137 bits (345), Expect = 5e-32
Identities = 95/288 (32%), Positives = 150/288 (51%), Gaps = 30/288 (10%)
Query: 226 ISQSACREMSLCRELDNN-HLTKLVEIFLEK----KSIYMVSEFAEHDLLQIIHFHSHPE 280
+++ A RE+ L N+ ++T + ++ + +Y+ E E DL II
Sbjct: 63 LTKRALREIKLLIHFRNHRNITCIYDLDIINPYNFNEVYIYEELMEADLNAIIK-----S 117
Query: 281 KRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGCVKIGDLGLARKFN-N 339
+ + +S ++QIL G+ Y+H ++HRDLKP N++V D +KI D GLAR + N
Sbjct: 118 GQPLTDAHFQSFIYQILCGLKYIHSANVIHRDLKPGNLLVNADCELKICDFGLARGCSEN 177
Query: 340 MVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELIGLRPIFKGEEAKME 399
+ + + T WYRAPE++L Y ID+W+VGCI AEL+G P+FKG++
Sbjct: 178 PEENPGFMTEYVATRWYRAPEIMLSFSSYHKGIDVWSVGCILAELLGGTPLFKGKDF--- 234
Query: 400 SKKSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPKYRDNLTAWYQTAGGK- 458
+Q IL +G+PD + +I S + +PK R ++T K
Sbjct: 235 --------VHQLNLILHQLGTPDEETLSHISSSRAQEYVRSLPKQR---PIPFETNFPKA 283
Query: 459 DKTALDILYRLLQYDPIKRIDAIDALDHVYFT----NGDPPVCENVFE 502
+ ALD+L +LL +DP +RI DAL+H Y D PVC++VF+
Sbjct: 284 NPLALDLLAKLLAFDPNRRISVDDALEHPYLAVWHDPSDEPVCDSVFD 331
>At2g46070 [T] KOG0660 Mitogen-activated protein kinase
Length = 406
Score = 137 bits (345), Expect = 5e-32
Identities = 89/289 (30%), Positives = 152/289 (51%), Gaps = 36/289 (12%)
Query: 232 REMSLCRELDNNHLTKLVEIFLEKK-----SIYMVSEFAEHDLLQIIHFHSHPEKRLIPP 286
RE+ L R +D+ ++ + +I + +Y+V E + DL +I+ + +
Sbjct: 121 REIKLLRHMDHENVITIKDIVRPPQRDIFNDVYIVYELMDTDLQRILR-----SNQTLTS 175
Query: 287 RMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGCVKIGDLGLARKFNNM-VQTLY 345
+ +++Q+L G+ Y+H ILHRDL+P+N+++ +KIGD GLAR ++ T Y
Sbjct: 176 DQCRFLVYQLLRGLKYVHSANILHRDLRPSNVLLNSKNELKIGDFGLARTTSDTDFMTEY 235
Query: 346 TGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELIGLRPIFKGEEAKMESKKSVL 405
+VT WYRAPEL+L YT AID+W+VGCI E++ +P+F G++
Sbjct: 236 -----VVTRWYRAPELLLNCSEYTAAIDIWSVGCILGEIMTGQPLFPGKD---------- 280
Query: 406 FQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPKY-RDNLTAWYQTAGGKDKTALD 464
+Q + I E++GSPD+ + S + ++P+Y + A + TA+D
Sbjct: 281 -YVHQLRLITELVGSPDNSSLGFLRSDNARRYVRQLPRYPKQQFAARFPK---MPTTAID 336
Query: 465 ILYRLLQYDPIKRIDAIDALDHVYFTN----GDPPVCENVFEGLNYKYP 509
+L R+L +DP +RI +AL H Y + PVC F ++++P
Sbjct: 337 LLERMLVFDPNRRISVDEALGHAYLSPHHDVAKEPVCSTPF-SFDFEHP 384
>Hs4507281 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 1030
Score = 135 bits (341), Expect = 1e-31
Identities = 86/284 (30%), Positives = 148/284 (51%), Gaps = 23/284 (8%)
Query: 206 QFYAIKKFKTEREGVEHYTGISQSACREMSLCRELDNNHLTKLVEIFLEKKSIYMVSEFA 265
+ AIKKFK E E + ++ RE+ + R L ++ +L E F + +Y+V E+
Sbjct: 37 EIVAIKKFKDSEENEE----VKETTLRELKMLRTLKQENIVELKEAFRRRGKLYLVFEYV 92
Query: 266 EHDLLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGC 325
E ++L+++ + +PP +KS ++Q++ + + H+N I+HRD+KP N++++ +
Sbjct: 93 EKNMLELLEEMPNG----VPPEKVKSYIYQLIKAIHWCHKNDIVHRDIKPENLLISHNDV 148
Query: 326 VKIGDLGLARKFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELI 385
+K+ D G AR + YT + + T WYR+PEL+LGA Y ++D+W+VGCI EL
Sbjct: 149 LKLCDFGFARNLSEGNNANYT--EYVATRWYRSPELLLGA-PYGKSVDMWSVGCILGELS 205
Query: 386 GLRPIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPKYR 445
+P+F GE S + Q QK+L + S K++ S P + L + P
Sbjct: 206 DGQPLFPGE--------SEIDQLFTIQKVLGPLPSEQMKLF---YSNPRFHGL-RFPAVN 253
Query: 446 DNLTAWYQTAGGKDKTALDILYRLLQYDPIKRIDAIDALDHVYF 489
+ + G + LD++ LL+ DP R L+H F
Sbjct: 254 HPQSLERRYLGILNSVLLDLMKNLLKLDPADRYLTEQCLNHPTF 297
>CE29478 [T] KOG0664 Nemo-like MAPK-related serine/threonine protein kinase
Length = 437
Score = 135 bits (341), Expect = 1e-31
Identities = 93/277 (33%), Positives = 148/277 (52%), Gaps = 44/277 (15%)
Query: 232 REMSLCRELDNNHLTKLVEIFLEK-----KSIYMVSEFAEHDLLQIIHFHSHPEKRLIPP 286
RE+ + ++++ L++I + +Y+++E + DL +II + + P
Sbjct: 89 REIKMLSSFRHDNVLSLLDILQPANPSFFQELYVLTELMQSDLHKII-----VSPQALTP 143
Query: 287 RMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGCVKIGDLGLARKFNNMVQTLYT 346
+K ++QIL G+ YLH ILHRD+KP N++V + +KI D GLAR ++ + T
Sbjct: 144 DHVKVFVYQILRGLKYLHTANILHRDIKPGNLLVNSNCILKICDFGLARTWDQRDRLNMT 203
Query: 347 GDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELIGLRPIFKGEEAKMESKKSVLF 406
+ +VT +YRAPEL++GAR YT A+D+W+VGCIFAEL+ ++ +LF
Sbjct: 204 HE--VVTQYYRAPELLMGARRYTGAVDIWSVGCIFAELL---------------QRKILF 246
Query: 407 QA----NQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPKYRDNLTA-----WYQTAGG 457
QA Q Q I++++G+P ++ + AK R L A Y+ A
Sbjct: 247 QAAGPIEQLQMIIDLLGTPSQ------EAMKYACEGAKNHVLRAGLRAPDTQRLYKIASP 300
Query: 458 KDKT--ALDILYRLLQYDPIKRIDAIDALDHVYFTNG 492
DK A+D+L +LL +DP KRI +AL H Y G
Sbjct: 301 DDKNHEAVDLLQKLLHFDPDKRISVEEALQHRYLEEG 337
>CE29477 [T] KOG0664 Nemo-like MAPK-related serine/threonine protein kinase
Length = 462
Score = 135 bits (341), Expect = 1e-31
Identities = 93/277 (33%), Positives = 148/277 (52%), Gaps = 44/277 (15%)
Query: 232 REMSLCRELDNNHLTKLVEIFLEK-----KSIYMVSEFAEHDLLQIIHFHSHPEKRLIPP 286
RE+ + ++++ L++I + +Y+++E + DL +II + + P
Sbjct: 114 REIKMLSSFRHDNVLSLLDILQPANPSFFQELYVLTELMQSDLHKII-----VSPQALTP 168
Query: 287 RMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGCVKIGDLGLARKFNNMVQTLYT 346
+K ++QIL G+ YLH ILHRD+KP N++V + +KI D GLAR ++ + T
Sbjct: 169 DHVKVFVYQILRGLKYLHTANILHRDIKPGNLLVNSNCILKICDFGLARTWDQRDRLNMT 228
Query: 347 GDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELIGLRPIFKGEEAKMESKKSVLF 406
+ +VT +YRAPEL++GAR YT A+D+W+VGCIFAEL+ ++ +LF
Sbjct: 229 HE--VVTQYYRAPELLMGARRYTGAVDIWSVGCIFAELL---------------QRKILF 271
Query: 407 QA----NQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPKYRDNLTA-----WYQTAGG 457
QA Q Q I++++G+P ++ + AK R L A Y+ A
Sbjct: 272 QAAGPIEQLQMIIDLLGTPSQ------EAMKYACEGAKNHVLRAGLRAPDTQRLYKIASP 325
Query: 458 KDKT--ALDILYRLLQYDPIKRIDAIDALDHVYFTNG 492
DK A+D+L +LL +DP KRI +AL H Y G
Sbjct: 326 DDKNHEAVDLLQKLLHFDPDKRISVEEALQHRYLEEG 362
>CE29476 [T] KOG0664 Nemo-like MAPK-related serine/threonine protein kinase
Length = 634
Score = 135 bits (341), Expect = 1e-31
Identities = 93/277 (33%), Positives = 148/277 (52%), Gaps = 44/277 (15%)
Query: 232 REMSLCRELDNNHLTKLVEIFLEK-----KSIYMVSEFAEHDLLQIIHFHSHPEKRLIPP 286
RE+ + ++++ L++I + +Y+++E + DL +II + + P
Sbjct: 286 REIKMLSSFRHDNVLSLLDILQPANPSFFQELYVLTELMQSDLHKII-----VSPQALTP 340
Query: 287 RMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGCVKIGDLGLARKFNNMVQTLYT 346
+K ++QIL G+ YLH ILHRD+KP N++V + +KI D GLAR ++ + T
Sbjct: 341 DHVKVFVYQILRGLKYLHTANILHRDIKPGNLLVNSNCILKICDFGLARTWDQRDRLNMT 400
Query: 347 GDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELIGLRPIFKGEEAKMESKKSVLF 406
+ +VT +YRAPEL++GAR YT A+D+W+VGCIFAEL+ ++ +LF
Sbjct: 401 HE--VVTQYYRAPELLMGARRYTGAVDIWSVGCIFAELL---------------QRKILF 443
Query: 407 QA----NQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPKYRDNLTA-----WYQTAGG 457
QA Q Q I++++G+P ++ + AK R L A Y+ A
Sbjct: 444 QAAGPIEQLQMIIDLLGTPSQ------EAMKYACEGAKNHVLRAGLRAPDTQRLYKIASP 497
Query: 458 KDKT--ALDILYRLLQYDPIKRIDAIDALDHVYFTNG 492
DK A+D+L +LL +DP KRI +AL H Y G
Sbjct: 498 DDKNHEAVDLLQKLLHFDPDKRISVEEALQHRYLEEG 534
>At4g19110 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 256
Score = 135 bits (340), Expect = 2e-31
Identities = 86/264 (32%), Positives = 142/264 (53%), Gaps = 35/264 (13%)
Query: 232 REMSLCRELDNNHLTKLVEIFLEKKSIYMVSEFAEHDLLQIIHFHSHPEKRLIPPRMLKS 291
RE+ R +++ ++ KL E+ E +Y V E+ E +L Q++ ++L +K+
Sbjct: 15 REVKSLRRMNHPNIVKLKEVIRENDILYFVFEYMECNLYQLMK----DRQKLFAEADIKN 70
Query: 292 IMWQILDGVSYLHQNWILHRDLKPANIMVTVDGCVKIGDLGLARKFNNMVQTLYTGDKVI 351
+Q+ G+SY+HQ HRDLKP N++V+ D +KI D GLAR+ N+ + +
Sbjct: 71 WCFQVFQGLSYMHQRGYFHRDLKPENLLVSKD-IIKIADFGLAREVNSSPPFT----EYV 125
Query: 352 VTIWYRAPELILGARHYTPAIDLWAVGCIFAELIGLRPIFKGEEAKMESKKSVLFQANQF 411
T WYRAPE++L + YT +D+WA+G I AEL+ LRPIF G +A++
Sbjct: 126 STRWYRAPEVLLQSYVYTSKVDMWAMGAIMAELLSLRPIFPGAS-----------EADEI 174
Query: 412 QKILEVMGSPDHKIW------PNIDSYPEYLQLAKMPKYRDNLTAWYQTAGGKDKTALDI 465
KI V+G+P + W N +Y ++ QL +P L++ +A + A+++
Sbjct: 175 YKICSVIGTPTEETWLEGLNLANTINY-QFPQLPGVP-----LSSLMPSA---SEDAINL 225
Query: 466 LYRLLQYDPIKRIDAIDALDHVYF 489
+ RL +DP R A + L H +F
Sbjct: 226 IERLCSWDPSSRPTAAEVLQHPFF 249
>Hs4506091 [T] KOG0660 Mitogen-activated protein kinase
Length = 721
Score = 134 bits (338), Expect = 3e-31
Identities = 100/313 (31%), Positives = 156/313 (48%), Gaps = 53/313 (16%)
Query: 209 AIKKFK-TEREGVEHYTGISQSACREMSLCRELDNNHLTKLVEIF--------------L 253
AIKK T+ + V+H A RE+ + R LD++++ K+ EI
Sbjct: 47 AIKKIVLTDPQSVKH-------ALREIKIIRRLDHDNIVKVFEILGPSGSQLTDDVGSLT 99
Query: 254 EKKSIYMVSEFAEHDLLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDL 313
E S+Y+V E+ E DL ++ E+ + + M+Q+L G+ Y+H +LHRDL
Sbjct: 100 ELNSVYIVQEYMETDLANVL------EQGPLLEEHARLFMYQLLRGLKYIHSANVLHRDL 153
Query: 314 KPANIMV-TVDGCVKIGDLGLARKFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAI 372
KPAN+ + T D +KIGD GLAR + + +VT WYR+P L+L +YT AI
Sbjct: 154 KPANLFINTEDLVLKIGDFGLARIMDPHYSHKGHLSEGLVTKWYRSPRLLLSPNNYTKAI 213
Query: 373 DLWAVGCIFAELIGLRPIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHKIWPNIDSY 432
D+WA GCIFAE++ + +F G + Q Q ILE + P +
Sbjct: 214 DMWAAGCIFAEMLTGKTLFAGAH-----------ELEQMQLILESI--------PVVHEE 254
Query: 433 PEYLQLAKMPKY-RDNLTAWY----QTAGGKDKTALDILYRLLQYDPIKRIDAIDALDHV 487
L+ +P Y R+++T + Q G + ALD L ++L + P+ R+ A +AL H
Sbjct: 255 DRQELLSVIPVYIRNDMTEPHKPLTQLLPGISREALDFLEQILTFSPMDRLTAEEALSHP 314
Query: 488 YFTNGDPPVCENV 500
Y + P+ E +
Sbjct: 315 YMSIYSFPMDEPI 327
>At1g18670 [D] KOG0600 Cdc2-related protein kinase
Length = 662
Score = 134 bits (338), Expect = 3e-31
Identities = 95/309 (30%), Positives = 150/309 (47%), Gaps = 26/309 (8%)
Query: 232 REMSLCRELDNNHLTKLVEIFLEKKS--IYMVSEFAEHDLLQIIHFHSHPEKRLIPPRML 289
RE+ + R+L++ ++ KL I K S I++V E+ EHDL ++ S P+ P+ +
Sbjct: 177 REILILRKLNHPNIIKLEGIVTSKLSCSIHLVFEYMEHDLTGLL---SSPDIDFTTPQ-I 232
Query: 290 KSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGCVKIGDLGLARKFNNMVQTLYTGDK 349
K M Q+L G+ + H ++HRD+K +N++V +G +K+ D GLA F N
Sbjct: 233 KCYMKQLLSGLDHCHARGVMHRDIKGSNLLVNNEGILKVADFGLAN-FCNASGNKQPLTS 291
Query: 350 VIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELIGLRPIFKGEEAKMESKKSVLFQAN 409
+VT+WYR PEL+LGA Y ++DLW+VGC+FAEL+ +P+ +G +
Sbjct: 292 RVVTLWYRPPELLLGATEYGASVDLWSVGCVFAELLIGKPVLQGRT-----------EVE 340
Query: 410 QFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPKYRDNLTAWYQTAGGKDKTALDILYRL 469
Q KI ++ GSP W S + L K ++ D G ++++ L
Sbjct: 341 QLHKIFKLCGSPPEDYWKK--SKLPHAMLFKPQQHYDGCLRETLKLKGLSDADINLIETL 398
Query: 470 LQYDPIKRIDAIDALDHVYFTNGDPPVCENVFEGLNYKYPPRRI---HTNDNDITNVGND 526
L P KR A AL YFT+ P C+ L P + I H D + +
Sbjct: 399 LSIQPHKRGTASTALVSQYFTS-KPFACDP--SSLPVYSPSKEIDAKHREDTTRKKISGN 455
Query: 527 NNQANHSQK 535
+ S+K
Sbjct: 456 GRRGTESRK 464
>At3g45640 [T] KOG0660 Mitogen-activated protein kinase
Length = 370
Score = 134 bits (337), Expect = 4e-31
Identities = 90/283 (31%), Positives = 146/283 (50%), Gaps = 39/283 (13%)
Query: 232 REMSLCRELDNNHLTKLVEIF-----LEKKSIYMVSEFAEHDLLQIIHFHSHPEKRLIPP 286
RE+ L R LD+ ++ + ++ + +Y+ +E + DL QII + +
Sbjct: 84 REIKLLRHLDHENIIAIRDVVPPPLRRQFSDVYISTELMDTDLHQIIR-----SNQSLSE 138
Query: 287 RMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGCVKIGDLGLARKFN-NMVQTLY 345
+ ++Q+L G+ Y+H I+HRDLKP+N+++ + +KI D GLAR + N T Y
Sbjct: 139 EHCQYFLYQLLRGLKYIHSANIIHRDLKPSNLLLNANCDLKICDFGLARPTSENDFMTEY 198
Query: 346 TGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELIGLRPIFKGEEAKMESKKSVL 405
+VT WYRAPEL+L + YT AID+W+VGCIF EL+ +P+F G++
Sbjct: 199 -----VVTRWYRAPELLLNSSDYTAAIDVWSVGCIFMELMNRKPLFPGKD---------- 243
Query: 406 FQANQFQKILEVMGSP---DHKIWPNIDSYPEYLQLAKMPKYRDNLTAWYQTAGGKDKTA 462
+Q + + E++G+P D N D+ QL P R L + + A
Sbjct: 244 -HVHQMRLLTELLGTPTESDLGFTHNEDAKRYIRQLPNFP--RQPLAKLFSHV---NPMA 297
Query: 463 LDILYRLLQYDPIKRIDAIDALDHVYFTN----GDPPVCENVF 501
+D++ R+L +DP +RI AL+H Y D P+C+ F
Sbjct: 298 IDLVDRMLTFDPNRRITVEQALNHQYLAKLHDPNDEPICQKPF 340
>SPAC24B11.06c [T] KOG0660 Mitogen-activated protein kinase
Length = 349
Score = 134 bits (336), Expect = 5e-31
Identities = 87/282 (30%), Positives = 148/282 (51%), Gaps = 30/282 (10%)
Query: 226 ISQSACREMSLCRELDNNHLTKLVEIFLEK-KSIYMVSEFAEHDLLQIIHFHSHPEKRLI 284
+++ RE+ L + L + ++ L +IF+ + IY V+E DL +++ R +
Sbjct: 60 LAKRTYRELKLLKHLRHENIISLSDIFISPFEDIYFVTELLGTDLHRLL------TSRPL 113
Query: 285 PPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGCVKIGDLGLARKFNNMVQTL 344
+ ++ ++QIL G+ ++H ++HRDLKP+NI++ + +KI D GLAR +
Sbjct: 114 ETQFIQYFLYQILRGLKFVHSAGVIHRDLKPSNILINENCDLKICDFGLAR----IQDPQ 169
Query: 345 YTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELIGLRPIFKGEEAKMESKKSV 404
TG + T +YRAPE++L + Y +D+W+ GCIFAE+I +P+F G +
Sbjct: 170 MTG--YVSTRYYRAPEIMLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGRD--------- 218
Query: 405 LFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPKYRDNLTAWYQTAGGKDKTALD 464
NQF I E++G+P ++ I S + +P + + + D A+D
Sbjct: 219 --HVNQFSIITELLGTPPMEVIETICSKNTLRFVQSLP--QKEKVPFAEKFKNADPDAID 274
Query: 465 ILYRLLQYDPIKRIDAIDALDHVYFT----NGDPPVCENVFE 502
+L ++L +DP KRI A DAL H Y D PV + VF+
Sbjct: 275 LLEKMLVFDPRKRISAADALAHNYLAPYHDPTDEPVADEVFD 316
>At2g43790 [T] KOG0660 Mitogen-activated protein kinase
Length = 395
Score = 134 bits (336), Expect = 5e-31
Identities = 86/277 (31%), Positives = 146/277 (52%), Gaps = 36/277 (12%)
Query: 232 REMSLCRELDNNHLTKLVEIFLEK-----KSIYMVSEFAEHDLLQIIHFHSHPEKRLIPP 286
RE+ L R +D+ ++ + +I +Y+ E + DL QII + +
Sbjct: 109 REIKLLRHMDHENIVAIRDIIPPPLRNAFNDVYIAYELMDTDLHQIIR-----SNQALSE 163
Query: 287 RMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGCVKIGDLGLARKFNNM-VQTLY 345
+ ++QIL G+ Y+H +LHRDLKP+N+++ + +KI D GLAR + T Y
Sbjct: 164 EHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARVTSESDFMTEY 223
Query: 346 TGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELIGLRPIFKGEEAKMESKKSVL 405
+VT WYRAPEL+L + YT AID+W+VGCIF EL+ +P+F G +
Sbjct: 224 -----VVTRWYRAPELLLNSSDYTAAIDVWSVGCIFMELMDRKPLFPGRD---------- 268
Query: 406 FQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPKY-RDNLTAWYQTAGGKDKTALD 464
+Q + ++E++G+P + ++ + + ++P Y R ++T + T A+D
Sbjct: 269 -HVHQLRLLMELIGTPSEEELEFLNENAK-RYIRQLPPYPRQSITDKFPTV---HPLAID 323
Query: 465 ILYRLLQYDPIKRIDAIDALDHVYFTN----GDPPVC 497
++ ++L +DP +RI +DAL H Y + D P C
Sbjct: 324 LIEKMLTFDPRRRITVLDALAHPYLNSLHDISDEPEC 360
>At1g71530 [D] KOG0600 Cdc2-related protein kinase
Length = 655
Score = 134 bits (336), Expect = 5e-31
Identities = 91/283 (32%), Positives = 139/283 (48%), Gaps = 27/283 (9%)
Query: 232 REMSLCRELDNNHLTKLVEIFLEKKS--IYMVSEFAEHDLLQIIHFHSHPEKRLIPPRML 289
RE+ + R+LD+ ++ KL + + S +Y+V E+ EHDL + + P + P+ +
Sbjct: 193 REILILRKLDHPNVMKLEGLVTSRLSGSLYLVFEYMEHDLAGLA---ATPGIKFSEPQ-I 248
Query: 290 KSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGCVKIGDLGLARKFNNMVQTLYTGDK 349
K M Q+ G+ + H+ ILHRD+K +N+++ +G +KIGD GLA + T
Sbjct: 249 KCYMQQLFRGLEHCHRRGILHRDIKGSNLLINNEGVLKIGDFGLANFYRGDGDLQLTSR- 307
Query: 350 VIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELIGLRPIFKGEEAKMESKKSVLFQAN 409
+VT+WYRAPEL+LGA Y PAIDLW+ GCI EL +PI G +
Sbjct: 308 -VVTLWYRAPELLLGATEYGPAIDLWSAGCILTELFAGKPIMPGRT-----------EVE 355
Query: 410 QFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPKYRDNLTAWYQTAGGKDKTALDILYRL 469
Q KI ++ GSP W + P Y+ L +T +AL ++ +L
Sbjct: 356 QMHKIFKLCGSPSEDYWRRA-TLPLATSFKPSHPYKPVLA---ETFNHFPSSALMLINKL 411
Query: 470 LQYDPIKRIDAIDALDHVYFTNGDPPVCENVFEGLNYKYPPRR 512
L +P KR A L +FT P + +YPP +
Sbjct: 412 LAIEPEKRGSAASTLRSEFFTTEPLPANPSNLP----RYPPSK 450
>At5g39420 [D] KOG0600 Cdc2-related protein kinase
Length = 576
Score = 133 bits (335), Expect = 7e-31
Identities = 88/262 (33%), Positives = 141/262 (53%), Gaps = 35/262 (13%)
Query: 232 REMSLCRELDNNHLTKLVEIFLEK--KSIYMVSEFAEHDLLQIIHFHSHPEKRLIPPRML 289
RE+ + R+L++ ++ KL I + SIY+V E+ EHDL + S+P+ R P+ +
Sbjct: 151 REILILRKLNHPNIMKLEGIVTSRASSSIYLVFEYMEHDLAGL---SSNPDIRFTEPQ-I 206
Query: 290 KSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGCVKIGDLGLARKFNNMVQTLYTGDK 349
K M Q+L G+ + H ++HRD+K +NI+V G +K+GD GLA + T
Sbjct: 207 KCYMKQLLWGLEHCHMRGVIHRDIKASNILVNNKGVLKLGDFGLANVVTPSNKNQLTSR- 265
Query: 350 VIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELIGLRPIFKGEEAKMESKKSVLFQAN 409
+VT+WYRAPEL++G+ Y ++DLW+VGC+FAE++ +PI KG +
Sbjct: 266 -VVTLWYRAPELLMGSTSYGVSVDLWSVGCVFAEILMGKPILKGRT-----------EIE 313
Query: 410 QFQKILEVMGSPDHKIW-----PNIDSY-PEYLQLAKMPKYRDNLTAWYQTAGGKDKTAL 463
Q KI ++ GSP W P+ S+ P++ A + + +L+A T +
Sbjct: 314 QLHKIYKLCGSPQDSFWKRTKLPHATSFKPQHTYEATLRERCKDLSA----------TGV 363
Query: 464 DILYRLLQYDPIKRIDAIDALD 485
+L LL +P KR A AL+
Sbjct: 364 YLLETLLSMEPDKRGTASSALN 385
>At4g01370 [T] KOG0660 Mitogen-activated protein kinase
Length = 376
Score = 133 bits (335), Expect = 7e-31
Identities = 89/281 (31%), Positives = 143/281 (50%), Gaps = 35/281 (12%)
Query: 232 REMSLCRELDNNHLTKLVEIFLEKK-----SIYMVSEFAEHDLLQIIHFHSHPEKRLIPP 286
RE+ L + +D+ ++ + +I + +Y+V E + DL QII + +
Sbjct: 89 REIKLLKHMDHENVIAVKDIIKPPQRENFNDVYIVYELMDTDLHQIIR-----SNQPLTD 143
Query: 287 RMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGCVKIGDLGLAR-KFNNMVQTLY 345
+ ++Q+L G+ Y+H +LHRDLKP+N+++ + +K+GD GLAR K T Y
Sbjct: 144 DHCRFFLYQLLRGLKYVHSANVLHRDLKPSNLLLNANCDLKLGDFGLARTKSETDFMTEY 203
Query: 346 TGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELIGLRPIFKGEEAKMESKKSVL 405
+VT WYRAPEL+L YT AID+W+VGCI E + P+F G++
Sbjct: 204 -----VVTRWYRAPELLLNCSEYTAAIDIWSVGCILGETMTREPLFPGKD---------- 248
Query: 406 FQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPKY-RDNLTAWYQTAGGKDKTALD 464
+Q + I E++GSPD + S + ++P+Y R N A + A+D
Sbjct: 249 -YVHQLRLITELIGSPDDSSLGFLRSDNARRYVRQLPQYPRQNFAARFPNMSA---GAVD 304
Query: 465 ILYRLLQYDPIKRIDAIDALDHVYFTN----GDPPVCENVF 501
+L ++L +DP +RI +AL H Y + PVC F
Sbjct: 305 LLEKMLVFDPSRRITVDEALCHPYLAPLHDINEEPVCVRPF 345
>Hs21237745 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 424
Score = 133 bits (334), Expect = 9e-31
Identities = 93/298 (31%), Positives = 155/298 (51%), Gaps = 44/298 (14%)
Query: 209 AIKKFKTEREGVEHYTGISQSACREMSLCRELDNNHLTKLVEIFLEKKS------IYMVS 262
A+KK + H ++ A RE+ L + +++ ++ L+ +F +K+ +Y+V
Sbjct: 53 AVKKLSRPFQNQTH----AKRAYRELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVM 108
Query: 263 EFAEHDLLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTV 322
E + +L Q+IH E+ + +++Q+L G+ +LH I+HRDLKP+NI+V
Sbjct: 109 ELMDANLCQVIHMELDHER-------MSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKS 161
Query: 323 DGCVKIGDLGLAR-KFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIF 381
D +KI D GLAR N + T Y +VT +YRAPE+ILG Y +D+W+VGCI
Sbjct: 162 DCTLKILDFGLARTACTNFMMTPY-----VVTRYYRAPEVILG-MGYKENVDIWSVGCIM 215
Query: 382 AELIGLRPIFKGEEAKMESKKSVLFQANQFQKILEVMGSPD----HKIWPNIDSYPEYLQ 437
AE++ + +F G + +Q+ K++E +G+P K+ P + +Y E
Sbjct: 216 AEMVLHKVLFPGRD-----------YIDQWNKVIEQLGTPSAEFMKKLQPTVRNYVENRP 264
Query: 438 LAKMPKYRDNLTAW-YQTAGGKDK----TALDILYRLLQYDPIKRIDAIDALDHVYFT 490
K+ + W + + +DK A D+L ++L DP KRI +AL H Y T
Sbjct: 265 KYPGIKFEELFPDWIFPSESERDKIKTSQARDLLSKMLVIDPDKRISVDEALRHPYIT 322
>Hs21237742 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 382
Score = 133 bits (334), Expect = 9e-31
Identities = 93/298 (31%), Positives = 155/298 (51%), Gaps = 44/298 (14%)
Query: 209 AIKKFKTEREGVEHYTGISQSACREMSLCRELDNNHLTKLVEIFLEKKS------IYMVS 262
A+KK + H ++ A RE+ L + +++ ++ L+ +F +K+ +Y+V
Sbjct: 53 AVKKLSRPFQNQTH----AKRAYRELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVM 108
Query: 263 EFAEHDLLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTV 322
E + +L Q+IH E+ + +++Q+L G+ +LH I+HRDLKP+NI+V
Sbjct: 109 ELMDANLCQVIHMELDHER-------MSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKS 161
Query: 323 DGCVKIGDLGLAR-KFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIF 381
D +KI D GLAR N + T Y +VT +YRAPE+ILG Y +D+W+VGCI
Sbjct: 162 DCTLKILDFGLARTACTNFMMTPY-----VVTRYYRAPEVILG-MGYKENVDIWSVGCIM 215
Query: 382 AELIGLRPIFKGEEAKMESKKSVLFQANQFQKILEVMGSPD----HKIWPNIDSYPEYLQ 437
AE++ + +F G + +Q+ K++E +G+P K+ P + +Y E
Sbjct: 216 AEMVLHKVLFPGRD-----------YIDQWNKVIEQLGTPSAEFMKKLQPTVRNYVENRP 264
Query: 438 LAKMPKYRDNLTAW-YQTAGGKDK----TALDILYRLLQYDPIKRIDAIDALDHVYFT 490
K+ + W + + +DK A D+L ++L DP KRI +AL H Y T
Sbjct: 265 KYPGIKFEELFPDWIFPSESERDKIKTSQARDLLSKMLVIDPDKRISVDEALRHPYIT 322
>At4g10010 [D] KOG0600 Cdc2-related protein kinase
Length = 649
Score = 133 bits (334), Expect = 9e-31
Identities = 98/283 (34%), Positives = 139/283 (48%), Gaps = 27/283 (9%)
Query: 232 REMSLCRELDNNHLTKLVEIFLEKKS--IYMVSEFAEHDLLQIIHFHSHPEKRLIPPRML 289
RE+++ R+LD+ ++ KL + K S +Y+V E+ EHDL + P + + +
Sbjct: 202 REINILRKLDHPNVMKLECLVTSKLSGSLYLVFEYMEHDLSGLA---LRPGVKFTESQ-I 257
Query: 290 KSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGCVKIGDLGLARKFNNMVQTLYTGDK 349
K M Q+L G+ + H ILHRD+K N++V DG +KIGD GLA ++ T
Sbjct: 258 KCYMKQLLSGLEHCHSRGILHRDIKGPNLLVNNDGVLKIGDFGLANIYHPEQDQPLTSR- 316
Query: 350 VIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELIGLRPIFKGEEAKMESKKSVLFQAN 409
+VT+WYRAPEL+LGA Y P IDLW+VGCI EL +PI G +
Sbjct: 317 -VVTLWYRAPELLLGATEYGPGIDLWSVGCILTELFLGKPIMPGRT-----------EVE 364
Query: 410 QFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPKYRDNLTAWYQTAGGKDKTALDILYRL 469
Q KI + GSP W P Y+ L +T +AL ++ +L
Sbjct: 365 QMHKIFKFCGSPSDDYWQK-TKLPLATSFKPQQPYKRVL---LETFKNLPPSALALVDKL 420
Query: 470 LQYDPIKRIDAIDALDHVYFTNGDPPVCENVFEGLNYKYPPRR 512
L +P KR A L +FT +P C NV KYPP +
Sbjct: 421 LSLEPAKRGTASSTLSSKFFTM-EPLPC-NV--SSLPKYPPSK 459
>CE06686 [T] KOG0660 Mitogen-activated protein kinase
Length = 377
Score = 132 bits (333), Expect = 1e-30
Identities = 94/304 (30%), Positives = 152/304 (49%), Gaps = 43/304 (14%)
Query: 209 AIKKFKTEREGVEHYTGISQSACREMSLCRELDNNHLTKLVEIFLEKKSI------YMVS 262
AIKKF + + H ++ RE+ L R + + ++ L+++F +++ Y VS
Sbjct: 62 AIKKFNRPFQSIIH----ARRTYRELRLLRCMCHENIIDLLDVFTPNENVNDIEDVYFVS 117
Query: 263 EFAEHDLLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTV 322
DL I+ + + + +++QIL G+ Y+H I+HRDLKP+NI V
Sbjct: 118 MLMGADLSNILKIQRLNDDHI------QFLVYQILRGLKYIHSADIIHRDLKPSNIAVNE 171
Query: 323 DGCVKIGDLGLARKFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFA 382
D +KI D GLAR+ ++ + TG + T WYRAPE++L HYT +D+W+VGCI A
Sbjct: 172 DCELKILDFGLARQTDSEM----TG--YVATRWYRAPEIMLNWMHYTQTVDVWSVGCILA 225
Query: 383 ELIGLRPIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMP 442
ELI + +F G + +Q +I+ V G+PD + I S + +P
Sbjct: 226 ELITGKTLFPGSD-----------HIDQLTRIMSVTGTPDEEFLKKISSEEARNYIRNLP 274
Query: 443 KY--RDNLTAWYQTAGGKDKTALDILYRLLQYDPIKRIDAIDALDH----VYFTNGDPPV 496
K RD + Q A+D+L ++L DP +R A +A++H Y D P+
Sbjct: 275 KMTRRDFKRLFAQAT----PQAIDLLEKMLHLDPDRRPTAKEAMEHEYLAAYHDETDEPI 330
Query: 497 CENV 500
E +
Sbjct: 331 AEEM 334
>HsM20070143 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 424
Score = 132 bits (332), Expect = 1e-30
Identities = 94/298 (31%), Positives = 154/298 (51%), Gaps = 44/298 (14%)
Query: 209 AIKKFKTEREGVEHYTGISQSACREMSLCRELDNNHLTKLVEIFLEKKS------IYMVS 262
A+KK + H ++ A RE+ L + +++ ++ L+ +F +K+ +Y+V
Sbjct: 53 AVKKLSRPFQNQTH----AKRAYRELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVM 108
Query: 263 EFAEHDLLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTV 322
E + +L Q+IH E+ + +++Q+L G+ +LH I+HRDLKP+NI+V
Sbjct: 109 ELMDANLCQVIHMELDHER-------MSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKS 161
Query: 323 DGCVKIGDLGLAR-KFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIF 381
D +KI D GLAR N + T Y +VT +YRAPE+ILG Y +D+W+VGCI
Sbjct: 162 DCTLKILDFGLARTACTNFMMTPY-----VVTRYYRAPEVILG-MGYKENVDIWSVGCIM 215
Query: 382 AELIGLRPIFKGEEAKMESKKSVLFQANQFQKILEVMGSPD----HKIWPNIDSYPEYLQ 437
EL+ IF+G + +Q+ K++E +G+P K+ P + +Y E
Sbjct: 216 GELVKGCVIFQGTD-----------HIDQWNKVIEQLGTPSAEFMKKLQPTVRNYVENRP 264
Query: 438 LAKMPKYRDNLTAW-YQTAGGKDK----TALDILYRLLQYDPIKRIDAIDALDHVYFT 490
K+ + W + + +DK A D+L ++L DP KRI +AL H Y T
Sbjct: 265 KYPGIKFEELFPDWIFPSESERDKIKTSQARDLLSKMLVIDPDKRISVDEALRHPYIT 322
>Hs21237739 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 382
Score = 132 bits (332), Expect = 1e-30
Identities = 94/298 (31%), Positives = 154/298 (51%), Gaps = 44/298 (14%)
Query: 209 AIKKFKTEREGVEHYTGISQSACREMSLCRELDNNHLTKLVEIFLEKKS------IYMVS 262
A+KK + H ++ A RE+ L + +++ ++ L+ +F +K+ +Y+V
Sbjct: 53 AVKKLSRPFQNQTH----AKRAYRELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVM 108
Query: 263 EFAEHDLLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTV 322
E + +L Q+IH E+ + +++Q+L G+ +LH I+HRDLKP+NI+V
Sbjct: 109 ELMDANLCQVIHMELDHER-------MSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKS 161
Query: 323 DGCVKIGDLGLAR-KFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIF 381
D +KI D GLAR N + T Y +VT +YRAPE+ILG Y +D+W+VGCI
Sbjct: 162 DCTLKILDFGLARTACTNFMMTPY-----VVTRYYRAPEVILG-MGYKENVDIWSVGCIM 215
Query: 382 AELIGLRPIFKGEEAKMESKKSVLFQANQFQKILEVMGSPD----HKIWPNIDSYPEYLQ 437
EL+ IF+G + +Q+ K++E +G+P K+ P + +Y E
Sbjct: 216 GELVKGCVIFQGTD-----------HIDQWNKVIEQLGTPSAEFMKKLQPTVRNYVENRP 264
Query: 438 LAKMPKYRDNLTAW-YQTAGGKDK----TALDILYRLLQYDPIKRIDAIDALDHVYFT 490
K+ + W + + +DK A D+L ++L DP KRI +AL H Y T
Sbjct: 265 KYPGIKFEELFPDWIFPSESERDKIKTSQARDLLSKMLVIDPDKRISVDEALRHPYIT 322
>Hs21237736 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 424
Score = 132 bits (332), Expect = 1e-30
Identities = 94/298 (31%), Positives = 154/298 (51%), Gaps = 44/298 (14%)
Query: 209 AIKKFKTEREGVEHYTGISQSACREMSLCRELDNNHLTKLVEIFLEKKS------IYMVS 262
A+KK + H ++ A RE+ L + +++ ++ L+ +F +K+ +Y+V
Sbjct: 53 AVKKLSRPFQNQTH----AKRAYRELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVM 108
Query: 263 EFAEHDLLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTV 322
E + +L Q+IH E+ + +++Q+L G+ +LH I+HRDLKP+NI+V
Sbjct: 109 ELMDANLCQVIHMELDHER-------MSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKS 161
Query: 323 DGCVKIGDLGLAR-KFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIF 381
D +KI D GLAR N + T Y +VT +YRAPE+ILG Y +D+W+VGCI
Sbjct: 162 DCTLKILDFGLARTACTNFMMTPY-----VVTRYYRAPEVILG-MGYKENVDIWSVGCIM 215
Query: 382 AELIGLRPIFKGEEAKMESKKSVLFQANQFQKILEVMGSPD----HKIWPNIDSYPEYLQ 437
EL+ IF+G + +Q+ K++E +G+P K+ P + +Y E
Sbjct: 216 GELVKGCVIFQGTD-----------HIDQWNKVIEQLGTPSAEFMKKLQPTVRNYVENRP 264
Query: 438 LAKMPKYRDNLTAW-YQTAGGKDK----TALDILYRLLQYDPIKRIDAIDALDHVYFT 490
K+ + W + + +DK A D+L ++L DP KRI +AL H Y T
Sbjct: 265 KYPGIKFEELFPDWIFPSESERDKIKTSQARDLLSKMLVIDPDKRISVDEALRHPYIT 322
>CE23826 [D] KOG0669 Cyclin T-dependent kinase CDK9
Length = 489
Score = 132 bits (332), Expect = 1e-30
Identities = 103/334 (30%), Positives = 160/334 (47%), Gaps = 64/334 (19%)
Query: 209 AIKKFKTEREGVEHYTGISQSACREMSLCRELDNNHLTKLVEIFLEKKS----------I 258
A+KK E E G +A RE+ + +L + ++T L+E+ K +
Sbjct: 123 ALKKILMENEK----EGFPITALREVKMLEQLKHPNITDLIEVCSAKSTGTTGSKDRATF 178
Query: 259 YMVSEFAEHDLLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANI 318
Y+V HDL ++ S+P+ R+ +K++M ++ G++ LH++ ILHRD+K AN+
Sbjct: 179 YLVMALCAHDLAGLL---SNPKIRMSLVH-IKTMMKHLMSGLNKLHRSKILHRDMKAANV 234
Query: 319 MVTVDGCVKIGDLGLARKFNNMV-----QTLYTGDKVIVTIWYRAPELILGARHYTPAID 373
+++ DG +K+ D GLAR F + LYT +VT+WYR PEL+LG R Y ID
Sbjct: 235 LISKDGILKLADFGLARPFVQRENGAGPRPLYTNR--VVTLWYRPPELLLGDRQYGTKID 292
Query: 374 LWAVGCIFAELIGLRPIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHKIWPNIDSYP 433
+W GCI AE+ +PI +G+ + Q Q I + GS + +WPN + P
Sbjct: 293 VWGAGCIMAEMWTRQPIMQGDT-----------EQKQLQLISGLCGSINKDVWPNCVNMP 341
Query: 434 EYLQLAKMP-------KYR---------------DNLTAWY-----QTAGGKDKTALDIL 466
+ ++ P KYR D+ T + Q D AL +L
Sbjct: 342 LWSAMSSEPNSALPQGKYRILPNKMKNLMKFDAPDSKTDPFGKNVKQHDSATDDDALHLL 401
Query: 467 YRLLQYDPIKRIDAIDALDHVYFTNGDPPVCENV 500
LL DP KR + +A D ++F DP NV
Sbjct: 402 EILLAIDPDKRPTSDEAEDDIWFFK-DPVPMANV 434
>CE18824 [D] KOG0669 Cyclin T-dependent kinase CDK9
Length = 456
Score = 132 bits (332), Expect = 1e-30
Identities = 103/334 (30%), Positives = 160/334 (47%), Gaps = 64/334 (19%)
Query: 209 AIKKFKTEREGVEHYTGISQSACREMSLCRELDNNHLTKLVEIFLEKKS----------I 258
A+KK E E G +A RE+ + +L + ++T L+E+ K +
Sbjct: 123 ALKKILMENEK----EGFPITALREVKMLEQLKHPNITDLIEVCSAKSTGTTGSKDRATF 178
Query: 259 YMVSEFAEHDLLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANI 318
Y+V HDL ++ S+P+ R+ +K++M ++ G++ LH++ ILHRD+K AN+
Sbjct: 179 YLVMALCAHDLAGLL---SNPKIRMSLVH-IKTMMKHLMSGLNKLHRSKILHRDMKAANV 234
Query: 319 MVTVDGCVKIGDLGLARKFNNMV-----QTLYTGDKVIVTIWYRAPELILGARHYTPAID 373
+++ DG +K+ D GLAR F + LYT +VT+WYR PEL+LG R Y ID
Sbjct: 235 LISKDGILKLADFGLARPFVQRENGAGPRPLYTNR--VVTLWYRPPELLLGDRQYGTKID 292
Query: 374 LWAVGCIFAELIGLRPIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHKIWPNIDSYP 433
+W GCI AE+ +PI +G+ + Q Q I + GS + +WPN + P
Sbjct: 293 VWGAGCIMAEMWTRQPIMQGDT-----------EQKQLQLISGLCGSINKDVWPNCVNMP 341
Query: 434 EYLQLAKMP-------KYR---------------DNLTAWY-----QTAGGKDKTALDIL 466
+ ++ P KYR D+ T + Q D AL +L
Sbjct: 342 LWSAMSSEPNSALPQGKYRILPNKMKNLMKFDAPDSKTDPFGKNVKQHDSATDDDALHLL 401
Query: 467 YRLLQYDPIKRIDAIDALDHVYFTNGDPPVCENV 500
LL DP KR + +A D ++F DP NV
Sbjct: 402 EILLAIDPDKRPTSDEAEDDIWFFK-DPVPMANV 434
>At5g45430 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 530
Score = 132 bits (332), Expect = 1e-30
Identities = 90/284 (31%), Positives = 146/284 (50%), Gaps = 34/284 (11%)
Query: 209 AIKKFKTEREGVEHYTGISQSACREMSLCRELDNNHLTKLVEIFLEKKSIYMVSEFAEHD 268
AIK+ K + E + RE+ +++ ++ KL E+ E +Y V E+ E +
Sbjct: 39 AIKRMKKKYFSWEECVNL-----REVKSLSRMNHPNIVKLKEVIRENDILYFVFEYMECN 93
Query: 269 LLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGCVKI 328
L Q++ + +++ +Q+ G+SY+HQ HRDLKP N++V+ D +KI
Sbjct: 94 LYQLMK----DRPKHFAESDIRNWCFQVFQGLSYMHQRGYFHRDLKPENLLVSKD-VIKI 148
Query: 329 GDLGLARKFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELIGLR 388
DLGLAR+ ++ YT + + T WYRAPE++L + YT +D+WA+G I AEL+ LR
Sbjct: 149 ADLGLAREIDSSPP--YT--EYVSTRWYRAPEVLLQSYVYTSKVDMWAMGAIMAELLSLR 204
Query: 389 PIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHKIW---PNIDSYPEYLQLAKMPKYR 445
P+F G +A++ KI V+GSP + W N+ S Y Q + P
Sbjct: 205 PLFPGAS-----------EADEIYKICSVIGSPTEETWLEGLNLASVINY-QFPQFPGVH 252
Query: 446 DNLTAWYQTAGGKDKTALDILYRLLQYDPIKRIDAIDALDHVYF 489
+ Y +A A++++ RL +DP R +AL H +F
Sbjct: 253 LSSVMPYASA-----DAVNLIERLCSWDPCNRPTTAEALQHPFF 291
>At1g03740 [D] KOG0600 Cdc2-related protein kinase
Length = 542
Score = 132 bits (332), Expect = 1e-30
Identities = 95/306 (31%), Positives = 145/306 (47%), Gaps = 31/306 (10%)
Query: 209 AIKKFKTEREGVEHYTGISQSACREMSLCRELDNNHLTKLVEIFLE--KKSIYMVSEFAE 266
A+KK + + +E ++ RE+ + R LD+ ++ KL + S+Y+V E+ +
Sbjct: 240 ALKKVRFDLNDMESVKFMA----REIIVMRRLDHPNVLKLEGLITAPVSSSLYLVFEYMD 295
Query: 267 HDLLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGCV 326
HDLL + S P + P++ K M Q+L G+ + H +LHRD+K +N+++ G +
Sbjct: 296 HDLLGL---SSLPGVKFTEPQV-KCYMRQLLSGLEHCHSRGVLHRDIKGSNLLIDSKGVL 351
Query: 327 KIGDLGLARKFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELIG 386
KI D GLA F+ T +VT+WYR PEL+LGA HY +DLW+ GCI EL
Sbjct: 352 KIADFGLATFFDPAKSVSLTSH--VVTLWYRPPELLLGASHYGVGVDLWSTGCILGELYA 409
Query: 387 LRPIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPKYRD 446
+PI G+ + Q KI ++ GSP W P YR
Sbjct: 410 GKPILPGKT-----------EVEQLHKIFKLCGSPTENYWRK-QKLPSSAGFKTAIPYRR 457
Query: 447 NLTAWYQTAGGKDKTALDILYRLLQYDPIKRIDAIDALDHVYFTNGDPPVCENVFEGLNY 506
++ ++ + L +L LL DP R A AL+ YF P C+
Sbjct: 458 KVSEMFKDF---PASVLSLLETLLSIDPDHRSSADRALESEYFKT-KPFACD---PSNLP 510
Query: 507 KYPPRR 512
KYPP +
Sbjct: 511 KYPPSK 516
>7295173 [T] KOG0664 Nemo-like MAPK-related serine/threonine protein kinase
Length = 474
Score = 132 bits (332), Expect = 1e-30
Identities = 82/242 (33%), Positives = 128/242 (52%), Gaps = 29/242 (11%)
Query: 256 KSIYMVSEFAEHDLLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKP 315
+ IY+++E + DL +II H + +K ++QIL G+ YLH ILHRD+KP
Sbjct: 115 QEIYVITELLQSDLHKIIVSPQH-----LSADHIKVFLYQILRGLKYLHSARILHRDIKP 169
Query: 316 ANIMVTVDGCVKIGDLGLAR-----KFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTP 370
N++V + +KI D GLAR + +M Q +VT +YRAPE+++GARHY+
Sbjct: 170 GNLLVNSNCVLKICDFGLARVEEPDQAKHMTQE-------VVTQYYRAPEILMGARHYSS 222
Query: 371 AIDLWAVGCIFAELIGLRPIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHKIWPNID 430
A+D+W+VGCIF EL+G R +F+ + Q + I E++G+P + +
Sbjct: 223 AVDVWSVGCIFGELLGRRILFQAQN-----------PVQQLELITELLGTPTMEDMRHAC 271
Query: 431 SYPEYLQLAKMPKYRDNLTAWYQTAGGKDKTALDILYRLLQYDPIKRIDAIDALDHVYFT 490
L + PK + + Y + A+ +L ++L +DP KRI DAL H Y
Sbjct: 272 EGARTHMLRRAPK-PPSFSVLYTLSSHATHEAVHLLCQMLVFDPDKRISVTDALAHPYLD 330
Query: 491 NG 492
G
Sbjct: 331 EG 332
>Hs20128774 [T] KOG0660 Mitogen-activated protein kinase
Length = 364
Score = 132 bits (331), Expect = 2e-30
Identities = 87/297 (29%), Positives = 156/297 (52%), Gaps = 37/297 (12%)
Query: 206 QFYAIKKFKTEREGVEHYTGISQSACREMSLCRELDNNHLTKLVEIFLEKKSI------Y 259
Q A+KK + + H ++ RE+ L + L + ++ L+++F SI Y
Sbjct: 48 QKVAVKKLSRPFQSLIH----ARRTYRELRLLKHLKHENVIGLLDVFTPATSIEDFSEVY 103
Query: 260 MVSEFAEHDLLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIM 319
+V+ DL I+ + ++ + + +++Q+L G+ Y+H I+HRDLKP+N+
Sbjct: 104 LVTTLMGADLNNIVKCQALSDEHV------QFLVYQLLRGLKYIHSAGIIHRDLKPSNVA 157
Query: 320 VTVDGCVKIGDLGLARKFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGC 379
V D ++I D GLAR+ + + TG + T WYRAPE++L HY +D+W+VGC
Sbjct: 158 VNEDCELRILDFGLARQADEEM----TG--YVATRWYRAPEIMLNWMHYNQTVDIWSVGC 211
Query: 380 IFAELIGLRPIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLA 439
I AEL+ + +F G + +Q ++I+EV+G+P ++ I S +
Sbjct: 212 IMAELLQGKALFPGSD-----------YIDQLKRIMEVVGTPSPEVLAKISSEHARTYIQ 260
Query: 440 KMPKY-RDNLTAWYQTAGGKDKTALDILYRLLQYDPIKRIDAIDALDHVYFTNGDPP 495
+P + +L++ ++ G + A+D+L R+L D +R+ A +AL H YF+ P
Sbjct: 261 SLPPMPQKDLSSIFR---GANPLAIDLLGRMLVLDSDQRVSAAEALAHAYFSQYHDP 314
>Hs7706445 [T] KOG0664 Nemo-like MAPK-related serine/threonine protein kinase
Length = 515
Score = 131 bits (330), Expect = 3e-30
Identities = 84/242 (34%), Positives = 131/242 (53%), Gaps = 29/242 (11%)
Query: 256 KSIYMVSEFAEHDLLQIIHFHSHPEKRLIPPRMLKS-----IMWQILDGVSYLHQNWILH 310
+ IY+V+E + DL +II + P+ L S ++QIL G+ YLH ILH
Sbjct: 201 EEIYVVTELMQSDLHKII----------VSPQPLSSDHVKVFLYQILRGLKYLHSAGILH 250
Query: 311 RDLKPANIMVTVDGCVKIGDLGLARKFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTP 370
RD+KP N++V + +KI D GLAR + ++ + +V VT +YRAPE+++G+RHY+
Sbjct: 251 RDIKPGNLLVNSNCVLKICDFGLAR-VEELDESRHMTQEV-VTQYYRAPEILMGSRHYSN 308
Query: 371 AIDLWAVGCIFAELIGLRPIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHKIWPNID 430
AID+W+VGCIFAEL+G R +F+ + Q I +++G+P +
Sbjct: 309 AIDIWSVGCIFAELLGRRILFQAQS-----------PIQQLDLITDLLGTPSLEAMRTAC 357
Query: 431 SYPEYLQLAKMPKYRDNLTAWYQTAGGKDKTALDILYRLLQYDPIKRIDAIDALDHVYFT 490
+ + + P + +L Y + A+ +L R+L +DP KRI A DAL H Y
Sbjct: 358 EGAK-AHILRGPHKQPSLPVLYTLSSQATHEAVHLLCRMLVFDPSKRISAKDALAHPYLD 416
Query: 491 NG 492
G
Sbjct: 417 EG 418
>Hs4503069 [T] KOG0660 Mitogen-activated protein kinase
Length = 360
Score = 131 bits (330), Expect = 3e-30
Identities = 94/312 (30%), Positives = 155/312 (49%), Gaps = 41/312 (13%)
Query: 209 AIKKFKTEREGVEHYTGISQSACREMSLCRELDNNHLTKLVEIFLEKKS------IYMVS 262
A+KK + + H ++ RE+ L + + + ++ L+++F +S +Y+V+
Sbjct: 51 AVKKLSRPFQSIIH----AKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVT 106
Query: 263 EFAEHDLLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTV 322
DL I+ + + + +++QIL G+ Y+H I+HRDLKP+N+ V
Sbjct: 107 HLMGADLNNIVKCQKLTDDHV------QFLIYQILRGLKYIHSADIIHRDLKPSNLAVNE 160
Query: 323 DGCVKIGDLGLARKFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFA 382
D +KI D GLAR ++ + TG + T WYRAPE++L HY +D+W+VGCI A
Sbjct: 161 DCELKILDFGLARHTDDEM----TG--YVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMA 214
Query: 383 ELIGLRPIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHKIWPNIDSYP--EYLQ-LA 439
EL+ R +F G + NQ Q+I+ + G+P + + S+ Y+Q L
Sbjct: 215 ELLTGRTLFPGTD-----------HINQLQQIMRLTGTPPAYLINRMPSHEARNYIQSLT 263
Query: 440 KMPKYRDNLTAWYQTAGGKDKTALDILYRLLQYDPIKRIDAIDALDHVYFTNGDPPVCEN 499
+MPK + G + A+D+L ++L D KRI A AL H YF P E
Sbjct: 264 QMPKMN-----FANVFIGANPLAVDLLEKMLVLDSDKRITAAQALAHAYFAQYHDPDDEP 318
Query: 500 VFEGLNYKYPPR 511
V + + + R
Sbjct: 319 VADPYDQSFESR 330
>Hs20986499 [T] KOG0660 Mitogen-activated protein kinase
Length = 677
Score = 131 bits (330), Expect = 3e-30
Identities = 82/242 (33%), Positives = 125/242 (50%), Gaps = 23/242 (9%)
Query: 266 EHDLLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGC 325
E DL QIIH S P + ++ ++Q+L G+ Y+H ++HRDLKP+N++V +
Sbjct: 2 ESDLHQIIH-SSQP----LTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCE 56
Query: 326 VKIGDLGLARKF-NNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAEL 384
+KIGD G+AR + + Y + + T WYRAPEL+L YT AIDLW+VGCIF E+
Sbjct: 57 LKIGDFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEM 116
Query: 385 IGLRPIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPKY 444
+ R +F G+ +Q Q I+ V+G+P + + + + +P
Sbjct: 117 LARRQLFPGKN-----------YVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPR 165
Query: 445 RDNLTAWYQTAGGKDKTALDILYRLLQYDPIKRIDAIDALDH----VYFTNGDPPVCENV 500
+ W G D+ AL +L R+L+++P RI A AL H Y D P C
Sbjct: 166 QP--VPWETVYPGADRQALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPP 223
Query: 501 FE 502
F+
Sbjct: 224 FD 225
>7302908 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 317
Score = 131 bits (330), Expect = 3e-30
Identities = 93/279 (33%), Positives = 148/279 (52%), Gaps = 45/279 (16%)
Query: 225 GISQSACREMSLCRELD-NNH--LTKLVEI--FLEKKS---IYMVSEFAEHDLLQIIHFH 276
G+ S RE+SL ++L+ +NH + KL E+ FLE+ I +V E E DL +I
Sbjct: 65 GVPMSTLREISLLKQLNASNHANIVKLYEVCQFLERDGQLLILLVFEHVEQDLSDLID-- 122
Query: 277 SHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGCVKIGDLGLARK 336
P+ + PP ++ + ++L GV +LH + I+HRDLKP N++V+ G +KI D GLA+
Sbjct: 123 RLPKSGMSPPT-IQRLSRELLTGVDFLHSHRIIHRDLKPQNLLVSSQGHLKIADFGLAKT 181
Query: 337 FNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELIGLRPIFKGEEA 396
+ + ++ V+VT+WYRAPE++L A+ Y +D+W+ CI E+ R +F G
Sbjct: 182 YGSEMKL----TSVVVTLWYRAPEVLL-AQPYNSTVDIWSAACIIFEMFNRRALFPGTSE 236
Query: 397 KMESKKSVLFQANQFQKILEVMGSPDHKIWPN-----IDSYPEYLQLAKMPK-YRDNLTA 450
K NQ +I E+ G P + WP ++ +P+ + K PK + +L
Sbjct: 237 K-----------NQLDRIFELTGRPTEQQWPQTISVALEHFPQ--RHPKRPKDFCPHLC- 282
Query: 451 WYQTAGGKDKTALDILYRLLQYDPIKRIDAIDALDHVYF 489
K A D+L ++L YD R A+ L+H YF
Sbjct: 283 ---------KYADDLLNKMLSYDLHLRPSALACLEHDYF 312
>At3g05050 [D] KOG0600 Cdc2-related protein kinase
Length = 593
Score = 131 bits (329), Expect = 3e-30
Identities = 88/285 (30%), Positives = 144/285 (49%), Gaps = 28/285 (9%)
Query: 232 REMSLCRELDNNHLTKLVEIFLEK--KSIYMVSEFAEHDLLQIIHFHSHPEKRLIPPRML 289
RE+ + R LD+ ++ KL + + S+Y+V + +HDL + + PE + + +
Sbjct: 184 REILILRRLDHPNVIKLEGLVTSRMSSSLYLVFRYMDHDLAGLA---ASPEIKFTE-QQV 239
Query: 290 KSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGCVKIGDLGLARKFNNMVQTLYTGDK 349
K M Q+L G+ + H +LHRD+K +N+++ G ++IGD GLA F+ + T
Sbjct: 240 KCYMKQLLSGLEHCHNRGVLHRDIKGSNLLIDDGGVLRIGDFGLATFFDASKRQEMTNR- 298
Query: 350 VIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELIGLRPIFKGEEAKMESKKSVLFQAN 409
+VT+WYR+PEL+ G Y+ +DLW+ GCI AEL+ R I G +
Sbjct: 299 -VVTLWYRSPELLHGVVEYSVGVDLWSAGCILAELLAGRAIMPGRN-----------EVE 346
Query: 410 QFQKILEVMGSPDHKIWPNI--DSYPEYLQLAKMPKYRDNLTAWYQTAGGKDKTALDILY 467
Q +I ++ GSP + W I S ++ +P+Y+ + Y+ + AL +L
Sbjct: 347 QLHRIYKLCGSPSEEYWKKIRLPSTHKHAHHKPLPQYKRRIREVYKDFSPE---ALSLLD 403
Query: 468 RLLQYDPIKRIDAIDALDHVYFTNGDPPVCENVFEGLNYKYPPRR 512
LL DP +R A D L +FT +P C+ KYPP +
Sbjct: 404 TLLALDPAERQTATDVLMSDFFTT-EPLACQ---PSDLPKYPPSK 444
>7301110 [T] KOG0660 Mitogen-activated protein kinase
Length = 366
Score = 131 bits (329), Expect = 3e-30
Identities = 91/299 (30%), Positives = 147/299 (48%), Gaps = 38/299 (12%)
Query: 209 AIKKFKTEREGVEHYTGISQSACREMSLCRELDNNHLTKLVEIF--------LEK-KSIY 259
AIKK + H ++ RE+ L + +D+ ++ L++IF LE + +Y
Sbjct: 52 AIKKLARPFQSAVH----AKRTYRELRLLKHMDHENVIGLLDIFHPHPANGSLENFQQVY 107
Query: 260 MVSEFAEHDLLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIM 319
+V+ + DL II + + + +++QIL G+ Y+H ++HRDLKP+NI
Sbjct: 108 LVTHLMDADLNNIIRMQHLSDDHV------QFLVYQILRGLKYIHSAGVIHRDLKPSNIA 161
Query: 320 VTVDGCVKIGDLGLARKFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGC 379
V D ++I D GLAR N + TG + T WYRAPE++L HY +D+W+VGC
Sbjct: 162 VNEDCELRILDFGLARPTENEM----TG--YVATRWYRAPEIMLNWMHYDQTVDIWSVGC 215
Query: 380 IFAELIGLRPIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLA 439
I AELI R +F G + +Q I+E++G+P + I S +
Sbjct: 216 IMAELITRRTLFPGTD-----------HIHQLNLIMEMLGTPPAEFLKKISSESARSYIQ 264
Query: 440 KMPKYRDNLTAWYQTAGGKDKTALDILYRLLQYDPIKRIDAIDALDHVYFTNGDPPVCE 498
+P + ++ + A+D+L ++L+ D KRI A +AL H Y P E
Sbjct: 265 SLPPMKGR--SFKNVFKNANPLAIDLLEKMLELDAEKRITAEEALSHPYLEKYAEPSVE 321
>Hs20986529 [T] KOG0660 Mitogen-activated protein kinase
Length = 360
Score = 130 bits (328), Expect = 4e-30
Identities = 91/303 (30%), Positives = 146/303 (48%), Gaps = 33/303 (10%)
Query: 209 AIKKFKTEREGVEHYTGISQSACREMSLCRELDNNHLTKLVEIFL-----EKKSIYMVSE 263
AIKK EH T Q RE+ + + ++ + +I + K +Y+V +
Sbjct: 52 AIKKISP----FEHQT-YCQRTLREIKILLRFRHENIIGINDIIRAPTIEQMKDVYIVQD 106
Query: 264 FAEHDLLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVD 323
E DL +++ + ++QIL G+ Y+H +LHRDLKP+N+++
Sbjct: 107 LMETDLYKLLKTQHLSNDHIC------YFLYQILRGLKYIHSANVLHRDLKPSNLLLNTT 160
Query: 324 GCVKIGDLGLARKFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAE 383
+KI D GLAR + + + T WYRAPE++L ++ YT +ID+W+VGCI AE
Sbjct: 161 CDLKICDFGLARVADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAE 220
Query: 384 LIGLRPIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPK 443
++ RPIF G+ +Q + IL ++GSP + I + L +P
Sbjct: 221 MLSNRPIFPGKH-----------YLDQLKHILGILGSPSQEDLNCIINLKARNYLLSLP- 268
Query: 444 YRDNLTAWYQTAGGKDKTALDILYRLLQYDPIKRIDAIDALDH----VYFTNGDPPVCEN 499
N W + D ALD+L ++L ++P KRI+ AL H Y+ D P+ E
Sbjct: 269 -HKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPYLEQYYDPSDEPIAEA 327
Query: 500 VFE 502
F+
Sbjct: 328 PFK 330
>Hs20986512 [T] KOG0660 Mitogen-activated protein kinase
Length = 360
Score = 130 bits (328), Expect = 4e-30
Identities = 94/312 (30%), Positives = 156/312 (49%), Gaps = 41/312 (13%)
Query: 209 AIKKFKTEREGVEHYTGISQSACREMSLCRELDNNHLTKLVEIFLEKKS------IYMVS 262
A+KK + + H ++ RE+ L + + + ++ L+++F +S +Y+V+
Sbjct: 51 AVKKLSRPFQSIIH----AKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVT 106
Query: 263 EFAEHDLLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTV 322
DL I+ + + + +++QIL G+ Y+H I+HRDLKP+N+ V
Sbjct: 107 HLMGADLNNIVKCQKLTDDHV------QFLIYQILRGLKYIHSADIIHRDLKPSNLAVNE 160
Query: 323 DGCVKIGDLGLARKFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFA 382
D +KI D GLAR ++ + TG + T WYRAPE++L HY +D+W+VGCI A
Sbjct: 161 DCELKILDFGLARHTDDEM----TG--YVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMA 214
Query: 383 ELIGLRPIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHKIWPNI--DSYPEYLQ-LA 439
EL+ R +F G + +Q + IL ++G+P ++ I +S Y+Q L
Sbjct: 215 ELLTGRTLFPGTD-----------HIDQLKLILRLVGTPGAELLKKISSESARNYIQSLT 263
Query: 440 KMPKYRDNLTAWYQTAGGKDKTALDILYRLLQYDPIKRIDAIDALDHVYFTNGDPPVCEN 499
+MPK + G + A+D+L ++L D KRI A AL H YF P E
Sbjct: 264 QMPKMN-----FANVFIGANPLAVDLLEKMLVLDSDKRITAAQALAHAYFAQYHDPDDEP 318
Query: 500 VFEGLNYKYPPR 511
V + + + R
Sbjct: 319 VADPYDQSFESR 330
>At5g44290 [D] KOG0600 Cdc2-related protein kinase
Length = 644
Score = 130 bits (328), Expect = 4e-30
Identities = 90/283 (31%), Positives = 138/283 (47%), Gaps = 27/283 (9%)
Query: 232 REMSLCRELDNNHLTKLVEIFLEK--KSIYMVSEFAEHDLLQIIHFHSHPEKRLIPPRML 289
RE+ + R LD+ ++ KL + S+Y+V E+ +HDL+ + S P + P++
Sbjct: 183 REIIVMRRLDHPNVLKLEGLITASVSSSLYLVFEYMDHDLVGLA---SIPGIKFSEPQV- 238
Query: 290 KSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGCVKIGDLGLARKFNNMVQTLYTGDK 349
K M Q+L G+ + H +LHRD+K +N+++ +G +KI D GLA F+ Q
Sbjct: 239 KCYMQQLLSGLHHCHSRGVLHRDIKGSNLLIDSNGVLKIADFGLATFFDP--QNCVPLTS 296
Query: 350 VIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELIGLRPIFKGEEAKMESKKSVLFQAN 409
+VT+WYR PEL+LGA HY +DLW+ GCI EL +PI G+ +
Sbjct: 297 RVVTLWYRPPELLLGACHYGVGVDLWSTGCILGELYSGKPILAGKT-----------EVE 345
Query: 410 QFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPKYRDNLTAWYQTAGGKDKTALDILYRL 469
Q KI ++ GSP W + P +P Y + ++ L +L L
Sbjct: 346 QLHKIFKLCGSPTEDYWRKLKLPPSAAFRPALP-YGRRVAEMFKDL---PTNVLSLLEAL 401
Query: 470 LQYDPIKRIDAIDALDHVYFTNGDPPVCENVFEGLNYKYPPRR 512
L DP +R A AL+ YF +P C+ KYPP +
Sbjct: 402 LSIDPDRRGSAARALESEYFRT-EPFACD---PSSLPKYPPSK 440
>At4g22940 [D] KOG0600 Cdc2-related protein kinase
Length = 458
Score = 130 bits (328), Expect = 4e-30
Identities = 88/278 (31%), Positives = 140/278 (49%), Gaps = 41/278 (14%)
Query: 232 REMSLCRELDNNHLTKLVEIFL---EKKSIYMVSEFAEHDLLQI-----IHFHSHPEKRL 283
RE+ + R+LD+ ++ KL + L + ++Y++ E+ EHDLL + +HF S P+
Sbjct: 149 REIIILRKLDHPNVIKLEGLMLVDHDSSTLYLIFEYMEHDLLGLSSLLGVHF-SEPQ--- 204
Query: 284 IPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGCVKIGDLGLARKF---NNM 340
+K M Q+L G+ + H N +LHRD+K +N+++ DG +KI D GLA F N++
Sbjct: 205 -----VKCYMRQLLRGLDHCHTNHVLHRDMKSSNLLINGDGVLKIADFGLATFFDPHNSV 259
Query: 341 VQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELIGLRPIFKGEEAKMES 400
T + + T+WYR PEL+LGA HY +DLW+ GC+ EL +PI G+
Sbjct: 260 PLTTH-----VATLWYRPPELLLGASHYGIGVDLWSTGCVIGELYAGKPILPGKN----- 309
Query: 401 KKSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPKYRDNLTAWYQTAGGKDK 460
+ +Q KI ++ GSP W + L + Y ++ +T
Sbjct: 310 ------ETDQLHKIFKLCGSPSDDYWTKL-KLQLSTPLRPIYPYGSHIA---ETFKQFPA 359
Query: 461 TALDILYRLLQYDPIKRIDAIDALDHVYFTNGDPPVCE 498
+ + +L LL DP R A AL YF +P C+
Sbjct: 360 SVISLLETLLSIDPDFRGTAASALKSKYFKT-EPLACD 396
>At1g07880 [T] KOG0660 Mitogen-activated protein kinase
Length = 363
Score = 130 bits (328), Expect = 4e-30
Identities = 92/285 (32%), Positives = 145/285 (50%), Gaps = 43/285 (15%)
Query: 232 REMSLCRELDNNHLTKLVEIF-LEKKS----IYMVSEFAEHDLLQIIHFHSHPEKRLIPP 286
RE+ L +D++++ K+ +I L +K +Y+V E + DL QII + +
Sbjct: 79 REIKLLSHMDHDNVIKIKDIIELPEKERFEDVYIVYELMDTDLHQIIR-----STQTLTD 133
Query: 287 RMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGCVKIGDLGLARKFNNM-VQTLY 345
+ ++QIL G+ Y+H +LHRDLKP+N+++ + +KI D GLAR N + T Y
Sbjct: 134 DHCQYFLYQILRGLKYIHSANVLHRDLKPSNLVLNTNCDLKICDFGLARTSNETEIMTEY 193
Query: 346 TGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELIGLRPIFKGEEAKMESKKSVL 405
+VT WYRAPEL+L + YT AID+W+VGCIF E++ +F G++
Sbjct: 194 -----VVTRWYRAPELLLNSSEYTGAIDIWSVGCIFMEILRRETLFPGKD---------- 238
Query: 406 FQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPKYRDNL-----TAWYQTAGGKDK 460
Q + I E++GSPD DS ++L+ KY L ++ +
Sbjct: 239 -YVQQLKLITELLGSPD-------DSDLDFLRSDNARKYVKQLPHVQKQSFREKFPNISP 290
Query: 461 TALDILYRLLQYDPIKRIDAIDALDHVYFTN----GDPPVCENVF 501
ALD+ ++L +DP KRI +AL Y + + P C F
Sbjct: 291 MALDLAEKMLVFDPSKRITVDEALKQPYLASLHEINEEPTCPTPF 335
>Hs20986531 [T] KOG0660 Mitogen-activated protein kinase
Length = 360
Score = 130 bits (327), Expect = 6e-30
Identities = 91/303 (30%), Positives = 145/303 (47%), Gaps = 33/303 (10%)
Query: 209 AIKKFKTEREGVEHYTGISQSACREMSLCRELDNNHLTKLVEIFL-----EKKSIYMVSE 263
AIKK EH T Q RE+ + + ++ + +I + K +Y+V +
Sbjct: 52 AIKKISP----FEHQT-YCQRTLREIKILLRFRHENIIGINDIIRAPTIEQMKDVYIVQD 106
Query: 264 FAEHDLLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVD 323
E DL +++ + ++QIL G+ Y+H +LHRDLKP+N+++
Sbjct: 107 LMETDLYKLLKTQHLSNDHIC------YFLYQILRGLKYIHSANVLHRDLKPSNLLLNTT 160
Query: 324 GCVKIGDLGLARKFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAE 383
+KI D GLAR + + + T WYRAPE++L ++ YT +ID+W+VGCI AE
Sbjct: 161 CDLKICDFGLARVADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAE 220
Query: 384 LIGLRPIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPK 443
++ RPIF G+ +Q IL ++GSP + I + L +P
Sbjct: 221 MLSNRPIFPGKH-----------YLDQLNHILGILGSPSQEDLNCIINLKARNYLLSLP- 268
Query: 444 YRDNLTAWYQTAGGKDKTALDILYRLLQYDPIKRIDAIDALDH----VYFTNGDPPVCEN 499
N W + D ALD+L ++L ++P KRI+ AL H Y+ D P+ E
Sbjct: 269 -HKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPYLEQYYDPSDEPIAEA 327
Query: 500 VFE 502
F+
Sbjct: 328 PFK 330
>Hs20562757 [T] KOG0660 Mitogen-activated protein kinase
Length = 379
Score = 129 bits (325), Expect = 1e-29
Identities = 92/302 (30%), Positives = 146/302 (47%), Gaps = 33/302 (10%)
Query: 209 AIKKFKTEREGVEHYTGISQSACREMSLCRELDNNHLTKLVEIFLEK-----KSIYMVSE 263
AIKK EH T Q RE+ + + ++ + +I + +Y+V +
Sbjct: 69 AIKKISP----FEHQT-YCQRTLREIQILLRFRHENVIGIRDILRASTLEAMRDVYIVQD 123
Query: 264 FAEHDLLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVD 323
E DL +++ + + + + ++QIL G+ Y+H +LHRDLKP+N+++
Sbjct: 124 LMETDLYKLL------KSQQLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLINTT 177
Query: 324 GCVKIGDLGLARKFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAE 383
+KI D GLAR + + + T WYRAPE++L ++ YT +ID+W+VGCI AE
Sbjct: 178 CDLKICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAE 237
Query: 384 LIGLRPIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPK 443
++ RPIF G+ +Q IL ++GSP + I + L +P
Sbjct: 238 MLSNRPIFPGKH-----------YLDQLNHILGILGSPSQEDLNCIINMKARNYLQSLPS 286
Query: 444 YRDNLTAWYQTAGGKDKTALDILYRLLQYDPIKRIDAIDALDH----VYFTNGDPPVCEN 499
AW + D ALD+L R+L ++P KRI +AL H Y+ D PV E
Sbjct: 287 --KTKVAWAKLFPKSDSKALDLLDRMLTFNPNKRITVEEALAHPYLEQYYDPTDEPVAEE 344
Query: 500 VF 501
F
Sbjct: 345 PF 346
>CE29073 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 700
Score = 129 bits (324), Expect = 1e-29
Identities = 85/283 (30%), Positives = 142/283 (50%), Gaps = 26/283 (9%)
Query: 206 QFYAIKKFKTEREGVEHYTGISQSACREMSLCRELDNNHLTKLVEIFLEKKSIYMVSEFA 265
+F A+K+ + E+E G +A RE+SL R L + ++ L +I + + +V E+
Sbjct: 385 KFVALKEIRLEQE-----EGAPCTAIREVSLLRNLRHANVVTLHDIIHTDRLLTLVFEYV 439
Query: 266 EHDLLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGC 325
+ DL Q + ++ + ++ ++Q+L G++Y HQ +LHRDLKP N+++T G
Sbjct: 440 DRDLKQYMDSCNNAMQM----NNIRLFLYQLLRGLAYCHQRRVLHRDLKPQNLLITAKGE 495
Query: 326 VKIGDLGLARKFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELI 385
+K+ D GLAR + +T Y+ + +VT+WYR P+++LG+ Y+ ID+W VGCI E+I
Sbjct: 496 LKLADFGLARAKSVPTKT-YSNE--VVTLWYRPPDVLLGSTDYSTHIDMWGVGCILFEMI 552
Query: 386 GLRPIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPKYR 445
R +F G Q I +GSP P I P + A
Sbjct: 553 AGRALFPGGT-----------PTEQLGLIFRTLGSPRPDRHPTICEKPTFYPYANRHYNP 601
Query: 446 DNLTAWYQTAGGKDKTALDILYRLLQYDPIKRIDAIDALDHVY 488
D L D ++L + LQY+ R+ A +A+ H +
Sbjct: 602 DPLCRQIPRI---DAHGFELLMKFLQYEGKDRVSAAEAVKHPF 641
>CE06779 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 577
Score = 129 bits (324), Expect = 1e-29
Identities = 85/283 (30%), Positives = 142/283 (50%), Gaps = 26/283 (9%)
Query: 206 QFYAIKKFKTEREGVEHYTGISQSACREMSLCRELDNNHLTKLVEIFLEKKSIYMVSEFA 265
+F A+K+ + E+E G +A RE+SL R L + ++ L +I + + +V E+
Sbjct: 262 KFVALKEIRLEQE-----EGAPCTAIREVSLLRNLRHANVVTLHDIIHTDRLLTLVFEYV 316
Query: 266 EHDLLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGC 325
+ DL Q + ++ + ++ ++Q+L G++Y HQ +LHRDLKP N+++T G
Sbjct: 317 DRDLKQYMDSCNNAMQM----NNIRLFLYQLLRGLAYCHQRRVLHRDLKPQNLLITAKGE 372
Query: 326 VKIGDLGLARKFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELI 385
+K+ D GLAR + +T Y+ + +VT+WYR P+++LG+ Y+ ID+W VGCI E+I
Sbjct: 373 LKLADFGLARAKSVPTKT-YSNE--VVTLWYRPPDVLLGSTDYSTHIDMWGVGCILFEMI 429
Query: 386 GLRPIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPKYR 445
R +F G Q I +GSP P I P + A
Sbjct: 430 AGRALFPGGT-----------PTEQLGLIFRTLGSPRPDRHPTICEKPTFYPYANRHYNP 478
Query: 446 DNLTAWYQTAGGKDKTALDILYRLLQYDPIKRIDAIDALDHVY 488
D L D ++L + LQY+ R+ A +A+ H +
Sbjct: 479 DPLCRQIPRI---DAHGFELLMKFLQYEGKDRVSAAEAVKHPF 518
>YLR113w [T] KOG0660 Mitogen-activated protein kinase
Length = 435
Score = 129 bits (323), Expect = 2e-29
Identities = 88/276 (31%), Positives = 148/276 (52%), Gaps = 26/276 (9%)
Query: 226 ISQSACREMSLCRELDNNHLTKLVEIFLEK-KSIYMVSEFAEHDLLQIIHFHSHPEKRLI 284
+++ RE+ L + L + +L L +IFL + IY V+E DL +++ + R +
Sbjct: 63 LAKRTYRELKLLKHLRHENLICLQDIFLSPLEDIYFVTELQGTDLHRLL------QTRPL 116
Query: 285 PPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGCVKIGDLGLARKFNNMVQTL 344
+ ++ ++QIL G+ Y+H ++HRDLKP+NI++ + +KI D GLAR +
Sbjct: 117 EKQFVQYFLYQILRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLAR----IQDPQ 172
Query: 345 YTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELIGLRPIFKGEEAKMESKKSV 404
TG + T +YRAPE++L + Y +D+W+ GCIFAE+I +P+F G++
Sbjct: 173 MTG--YVSTRYYRAPEIMLTWQKYDVEVDIWSAGCIFAEMIEGKPLFPGKD--------- 221
Query: 405 LFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPKYRDNLTAWYQTAGGKDKTALD 464
+QF I +++GSP + I S + +P +RD + + + + A+D
Sbjct: 222 --HVHQFSIITDLLGSPPKDVINTICSENTLKFVTSLP-HRDPI-PFSERFKTVEPDAVD 277
Query: 465 ILYRLLQYDPIKRIDAIDALDHVYFTNGDPPVCENV 500
+L ++L +DP KRI A DAL H Y P E V
Sbjct: 278 LLEKMLVFDPKKRITAADALAHPYSAPYHDPTDEPV 313
>At1g18150 [T] KOG0660 Mitogen-activated protein kinase
Length = 589
Score = 129 bits (323), Expect = 2e-29
Identities = 116/394 (29%), Positives = 167/394 (41%), Gaps = 45/394 (11%)
Query: 114 NGMNRDNVIILDSPDSVSADSNLDINSINRSTRQQEANDNLTTMDFRKPSH--------- 164
N N + I S S S++ N NS + LT ++ K +H
Sbjct: 31 NNNNHEQPIFNSSSFSSSSNPNHSANSGELIIEEDLDFSGLTLINVPKRNHLPMDPHKKG 90
Query: 165 --KRFTPPNNSNSTQIRSNSGSEXXXXXXXXXXXXXXXKPSQIQFYAIKKFKTEREGVEH 222
+ FT +N QI+ G + AIKK E V
Sbjct: 91 ETEFFTEYGEANRYQIQEVVGKGSYGVVASAVDSHTGER------VAIKKINDVFEHVSD 144
Query: 223 YTGISQSACREMSLCRELDNNHLTKLVEIFL-----EKKSIYMVSEFAEHDLLQIIHFHS 277
T I RE+ L R L + + ++ I L E + IY+V E E DL Q+I +
Sbjct: 145 ATRI----LREIKLLRLLRHPDVVEIKHIMLPPSRREFRDIYVVFELMESDLHQVIKAND 200
Query: 278 HPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGCVKIGDLGLARKF 337
+ P + ++Q+L G+ Y+H + HRDLKP NI+ D +KI D GLAR
Sbjct: 201 D-----LTPEHYQFFLYQLLRGLKYVHAANVFHRDLKPKNILANADCKLKICDFGLARVS 255
Query: 338 NNMVQTLYTGDKVIVTIWYRAPELILG-ARHYTPAIDLWAVGCIFAELIGLRPIFKGEEA 396
N T + T WYRAPEL YTPAID+W+VGCIFAE++ +P+F G+
Sbjct: 256 FNDAPTAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSVGCIFAEMLLGKPLFPGKNV 315
Query: 397 KMESKKSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPKYRDNLTAWYQTAG 456
+Q + + +G+P + I + L+ M K + +
Sbjct: 316 -----------VHQLDLMTDFLGTPPPESISRIRNEKARRYLSSMRKKQP--VPFSHKFP 362
Query: 457 GKDKTALDILYRLLQYDPIKRIDAIDALDHVYFT 490
D AL +L RLL +DP R A DAL YF+
Sbjct: 363 KADPLALRLLERLLAFDPKDRASAEDALADPYFS 396
>CE29020 [T] KOG0660 Mitogen-activated protein kinase
Length = 470
Score = 128 bits (322), Expect = 2e-29
Identities = 96/301 (31%), Positives = 146/301 (47%), Gaps = 38/301 (12%)
Query: 227 SQSACREMSLCRELDNN-HLTKLVEIFL--EKKSIYMVSEFAEHDLLQIIHFHSHPEKRL 283
SQ RE+ +E + ++ KL IF + IY+ EF E DL +I S +
Sbjct: 54 SQRTFREVMFLQEFGKHPNVIKLYNIFRADNDRDIYLAFEFMEADLHNVIKKGS-----I 108
Query: 284 IPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGCVKIGDLGLARKFNNMV-- 341
+ + IM Q+ + +LH +LHRDLKP+N+++ D VK+ D GLAR +++
Sbjct: 109 LKDVHKQYIMCQLFRAIRFLHSGNVLHRDLKPSNVLLDADCRVKLADFGLARSLSSLEDY 168
Query: 342 ---QTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELIGLRPIFKGEEAKM 398
Q + + + T WYR+PE++L A+ YT +D+W++GCI AE++ R +F G
Sbjct: 169 PEGQKMPDLTEYVATRWYRSPEILLAAKRYTKGVDMWSLGCILAEMLIGRALFPGSST-- 226
Query: 399 ESKKSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMP----KYRDNLTAWYQT 454
NQ ++I+ + P +I S+ L KMP K D + QT
Sbjct: 227 ---------INQIERIMNTIAKPSRADIASIGSHYAASVLEKMPQRPRKPLDLIITQSQT 277
Query: 455 AGGKDKTALDILYRLLQYDPIKRIDAIDALDHVYFTNGDPPVCENVFEGLNYK-YPPRRI 513
A A+D++ RLL + P KR+ L H Y P E V LNY+ YPP
Sbjct: 278 A------AIDMVQRLLIFAPQKRLTVEQCLVHPYVVQFHNPSEEPV---LNYEVYPPLPD 328
Query: 514 H 514
H
Sbjct: 329 H 329
>CE02602_1 [T] KOG0660 Mitogen-activated protein kinase
Length = 342
Score = 127 bits (320), Expect = 4e-29
Identities = 84/277 (30%), Positives = 144/277 (51%), Gaps = 35/277 (12%)
Query: 227 SQSACREMSLCRELDNNHLTKLVEIFLEK----KSIYMVSEFAEHDLLQIIHFHSHPEKR 282
++ A RE+ + REL + ++ ++ + + + IY+V + E DLL ++ +
Sbjct: 85 AKCALREIRITRELSHENIINSTDVLMRESGSGQDIYIVMDLMETDLLSVLK-----SNQ 139
Query: 283 LIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGCVKIGDLGLARKFNNMVQ 342
+ + + +QIL G+ YLH I+HRDLKPAN+++ D +KI D G++R +
Sbjct: 140 TLNEKHFQYFFYQILKGLKYLHSAGIIHRDLKPANLLLNEDCSLKIADFGMSRSGPSTKT 199
Query: 343 TLYT-------GD--KVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELIGLRPIFKG 393
T T GD + + T+WYRAPE++L Y +D+W+ GCI AE++ LRPIF G
Sbjct: 200 TPNTSPNAHISGDLSQYVSTLWYRAPEILLSMGEYDTQVDIWSAGCILAEMLLLRPIFTG 259
Query: 394 EEAKMESKKSVLFQANQFQKILEVMGSPDHKIWPNI--DSYPEYLQLAKMPKYRDNLTAW 451
++ +Q Q ++E +G+PD ++ I S +Y+ + PK TA
Sbjct: 260 TDS-----------YSQIQLLIEYLGTPDEQVIRRIKSPSIRDYIS-SFGPKTPLPFTAM 307
Query: 452 YQTAGGKDKTALDILYRLLQYDPIKRIDAIDALDHVY 488
+ A + A +I+ ++LQ P KR A L+ +
Sbjct: 308 FPNASIE---ARNIVSKMLQISPWKRFSAEQLLEEPF 341
>Hs7706059 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 455
Score = 127 bits (319), Expect = 5e-29
Identities = 89/285 (31%), Positives = 133/285 (46%), Gaps = 25/285 (8%)
Query: 206 QFYAIKKFKTEREGVEHYTGISQSACREMSLCRELDNNHLTKLVEIFLEKKSIYMVSEFA 265
Q AIK F E +++ A RE+ ++ + +L L+E+F +KK I++V EF
Sbjct: 28 QIVAIKIFYERPE-----QSVNKIAMREIKFLKQFHHENLVNLIEVFRQKKKIHLVFEFI 82
Query: 266 EHDLLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGC 325
+H +L + + H + + L+ ++QIL + YLH N I+HRD+KP NI+V+ G
Sbjct: 83 DHTVLDELQHYCHG----LESKRLRKYLFQILRAIDYLHSNNIIHRDIKPENILVSQSGI 138
Query: 326 VKIGDLGLARKFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELI 385
K+ D G AR +YT + T WYRAPEL+L Y +D+WA+GC+ E+
Sbjct: 139 TKLCDFGFARTL-AAPGDIYT--DYVATRWYRAPELVLKDTSYGKPVDIWALGCMIIEMA 195
Query: 386 GLRPIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPKYR 445
P K VL N + + I+ + L + PK
Sbjct: 196 TGNPYLPSSSDLDLLHKIVLKVGNLSPHLQNIFSK--SPIFAGV-----VLPQVQHPK-- 246
Query: 446 DNLTAWYQTAGGKDKTALDILYRLLQYDPIKRIDAIDALDHVYFT 490
N Y G DI++ LQ DP RI + D L H YFT
Sbjct: 247 -NARKKYPKLNG---LLADIVHACLQIDPADRISSSDLLHHEYFT 287
>At3g14720 [T] KOG0660 Mitogen-activated protein kinase
Length = 586
Score = 127 bits (319), Expect = 5e-29
Identities = 105/320 (32%), Positives = 158/320 (48%), Gaps = 35/320 (10%)
Query: 209 AIKKFKTEREGVEHYTGISQSACREMSLCRELDNNHLTKLVEIFL-----EKKSIYMVSE 263
AIKK E V I RE+ L R L + + ++ I L E K IY+V E
Sbjct: 40 AIKKINDVFEHVSDALRI----LREVKLLRLLRHPDIVEIKSIMLPPSKREFKDIYVVFE 95
Query: 264 FAEHDLLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVD 323
E DL Q+I + + + ++Q+L + Y+H + HRDLKP NI+ +
Sbjct: 96 LMESDLHQVIKANDD-----LTREHHQFFLYQMLRALKYMHTANVYHRDLKPKNILANAN 150
Query: 324 GCVKIGDLGLAR-KFNNMVQTLYTGDKVIVTIWYRAPELILG-ARHYTPAIDLWAVGCIF 381
+K+ D GLAR FN+ T++ D V T WYRAPEL YTPAID+W++GCIF
Sbjct: 151 CKLKVCDFGLARVSFNDTPTTVFWTDYV-ATRWYRAPELCGSFCSKYTPAIDIWSIGCIF 209
Query: 382 AELIGLRPIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKM 441
AE++ +P+F G KSV+ +Q I +++G+P + + + L +M
Sbjct: 210 AEVLTGKPLFPG--------KSVV---HQLDLITDLLGTPKSETIAGVRNEKARKYLNEM 258
Query: 442 PKYRDNLTAWYQTAGGKDKTALDILYRLLQYDPIKRIDAIDALDHVYF----TNGDPPVC 497
K NL + Q D AL +L RLL +DP R A +AL YF P C
Sbjct: 259 RK--KNLVPFSQKFPNADPLALRLLQRLLAFDPKDRPTAAEALADPYFKCLAKVEREPSC 316
Query: 498 ENVFEGLNYKYPPRRIHTND 517
+ + + + +++ RR+ +D
Sbjct: 317 QPISK-MEFEFERRRLTKDD 335
>7298087 [T] KOG0660 Mitogen-activated protein kinase
Length = 365
Score = 127 bits (319), Expect = 5e-29
Identities = 91/300 (30%), Positives = 146/300 (48%), Gaps = 40/300 (13%)
Query: 209 AIKKFKTEREGVEHYTGISQSACREMSLCRELDNNHLTKLVEIFL---------EKKSIY 259
AIKK + H ++ RE+ L + +D+ ++ L+++F + + +Y
Sbjct: 51 AIKKLARPFQSAVH----AKRTYRELRLLKHMDHENVIGLLDVFHPGQPADSLDQFQQVY 106
Query: 260 MVSEFAEHDLLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIM 319
MV+ + DL II + + + +++QIL G+ Y+H ++HRDLKP+NI
Sbjct: 107 MVTHLMDADLNNIIRTQKLSDDHV------QFLVYQILRGLKYIHSAGVIHRDLKPSNIA 160
Query: 320 VTVDGCVKIGDLGLARKFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGC 379
V D ++I D GLAR ++ TG + T WYRAPE++L HY D+W+VGC
Sbjct: 161 VNEDCELRILDFGLARP----AESEMTG--YVATRWYRAPEIMLNWMHYNQTADIWSVGC 214
Query: 380 IFAELIGLRPIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLA 439
I AEL+ R +F G + +Q I+EV+G+P + I S +
Sbjct: 215 IMAELLTGRTLFPGTD-----------HIHQLNLIMEVLGTPADEFMSRISSESARNYIR 263
Query: 440 KMPKY-RDNLTAWYQTAGGKDKTALDILYRLLQYDPIKRIDAIDALDHVYFTNGDPPVCE 498
+P R N ++ G + A+D+L ++L+ D KRI A AL H Y P E
Sbjct: 264 SLPVMPRRNFRDIFR---GANPLAIDLLEKMLELDADKRITAEQALAHPYMEKYHDPTDE 320
>CE29318 [T] KOG0660 Mitogen-activated protein kinase
Length = 474
Score = 127 bits (318), Expect = 6e-29
Identities = 88/310 (28%), Positives = 155/310 (49%), Gaps = 31/310 (10%)
Query: 206 QFYAIKKFKTEREGVEHYTGISQSACREMSLCRELDNNHLTKLVEIFL-----EKKSIYM 260
++ AIKK + H ++ RE L + + ++++ ++I+ + + +Y+
Sbjct: 145 RYVAIKKMREPFFDPHH----ARRIFRETKLLQLMRHDNIICALDIYTPDEENDFRDVYV 200
Query: 261 VSEFAEHDLLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMV 320
V+EFA L QI+ +R++ +K I++QI+ + Y+H I+HRDLKP N+ +
Sbjct: 201 VTEFAGRSLYQILKQQRDYGRRVLTDEHIKFIIYQIIRALKYIHSANIIHRDLKPGNLAL 260
Query: 321 TVDGCVKIGDLGLARKFNNMVQTLYTGDKVIVTIWYRAPELIL-GARHYTPAIDLWAVGC 379
T D + I D GLAR +L + + T WYR+PE+I YT D+W++GC
Sbjct: 261 TDDSDLMILDFGLARSLEKKDTSL---TQYVQTRWYRSPEVIYWKIDSYTNLADMWSLGC 317
Query: 380 IFAELIGLRPIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLA 439
I AEL+ P+F G+E Q+Q+I ++ GSPD ++ I++ A
Sbjct: 318 IAAELLTGEPLFPGDEPNA-----------QYQRITQLCGSPDEELLTKIENDNSSAIKA 366
Query: 440 KMPKYRDNLTAWYQ---TAGGKDKTALDILYRLLQYDPIKRIDAIDALDHVYFTN----G 492
+ Y + ++ +A + +D+L +LL DP KRI +A+ H Y
Sbjct: 367 VIQSYTTHKRRNFRDVFSAHNPSEDFIDLLEKLLVLDPEKRITVEEAIQHPYLAEFSLPE 426
Query: 493 DPPVCENVFE 502
D P +++F+
Sbjct: 427 DEPRADHIFD 436
>At1g53050 [D] KOG0600 Cdc2-related protein kinase
Length = 694
Score = 127 bits (318), Expect = 6e-29
Identities = 93/310 (30%), Positives = 144/310 (46%), Gaps = 30/310 (9%)
Query: 232 REMSLCRELDNNHLTKLVEIFLEKKS--IYMVSEFAEHDLLQIIHFHSHPEKRLIPPRML 289
RE+ + R LD+ ++ KL + + S +Y+V E+ EHDL + SHP + ++
Sbjct: 180 REIQILRRLDHPNIIKLEGLVTSRMSCSLYLVFEYMEHDLAGLA---SHPAIKFSESQV- 235
Query: 290 KSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGCVKIGDLGLARKFNNMVQTLYTGDK 349
K + Q+L G+ + H +LHRD+K +N+++ G +KI D GLA F+ T
Sbjct: 236 KCYLQQLLHGLDHCHSRGVLHRDIKGSNLLIDNSGVLKIADFGLASFFDPRQTQPLTSR- 294
Query: 350 VIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELIGLRPIFKGEEAKMESKKSVLFQAN 409
+VT+WYR PEL+LGA Y A+DLW+ GCI AEL +PI G +
Sbjct: 295 -VVTLWYRPPELLLGATRYGAAVDLWSAGCILAELYAGKPIMPGRT-----------EVE 342
Query: 410 QFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPKYRDNLTAWYQTAGGKDKTALDILYRL 469
Q KI ++ GSP W + S + + K + L +T + AL +L L
Sbjct: 343 QLHKIFKLCGSPTEDYW--VKSRLPHATIFKPTQPYKRLVG--ETFKEFPQPALALLETL 398
Query: 470 LQYDPIKRIDAIDALDHVYFTNGDPPVCENVFEGLNYKYPPRR---IHTNDNDITNVGND 526
L +P R A AL +F+ P + KYPP + D +
Sbjct: 399 LSVNPDDRGTATAALKSEFFSTRPLPCDPSSLP----KYPPSKELDARMRDEESRRQVGG 454
Query: 527 NNQANHSQKQ 536
N H +++
Sbjct: 455 NRDQRHQERR 464
>Hs4506085 [T] KOG0660 Mitogen-activated protein kinase
Length = 365
Score = 126 bits (317), Expect = 8e-29
Identities = 83/270 (30%), Positives = 142/270 (51%), Gaps = 34/270 (12%)
Query: 227 SQSACREMSLCRELDNNHLTKLVEIFLEKKSI------YMVSEFAEHDLLQIIHFHSHPE 280
++ A RE+ L + + + ++ L+++F S+ Y+V F + DL +I+ E
Sbjct: 66 AKRAYRELLLLKHMQHENVIGLLDVFTPASSLRNFYDFYLVMPFMQTDLQKIMGMEFSEE 125
Query: 281 KRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGCVKIGDLGLARKFNNM 340
K ++ +++Q+L G+ Y+H ++HRDLKP N+ V D +KI D GLAR +
Sbjct: 126 K-------IQYLVYQMLKGLKYIHSAGVVHRDLKPGNLAVNEDCELKILDFGLARHADAE 178
Query: 341 VQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELIGLRPIFKGEEAKMES 400
+ TG +VT WYRAPE+IL HY +D+W+VGCI AE++ + +FKG++
Sbjct: 179 M----TG--YVVTRWYRAPEVILSWMHYNQTVDIWSVGCIMAEMLTGKTLFKGKD----- 227
Query: 401 KKSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPKY-RDNLTAWYQTAGGKD 459
+Q +IL+V G P + ++ + +P+ R + T + A +
Sbjct: 228 ------YLDQLTQILKVTGVPGTEFVQKLNDKAAKSYIQSLPQTPRKDFTQLFPRASPQ- 280
Query: 460 KTALDILYRLLQYDPIKRIDAIDALDHVYF 489
A D+L ++L+ D KR+ A AL H +F
Sbjct: 281 --AADLLEKMLELDVDKRLTAAQALTHPFF 308
>Hs4506081 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 422
Score = 126 bits (317), Expect = 8e-29
Identities = 92/295 (31%), Positives = 151/295 (51%), Gaps = 42/295 (14%)
Query: 209 AIKKFKTEREGVEHYTGISQSACREMSLCRELDNNHLTKLVEIFLEKKS------IYMVS 262
AIKK + H ++ A RE+ L + +++ ++ L+ +F +K+ +Y+V
Sbjct: 91 AIKKLSRPFQNQTH----AKRAYRELVLMKCVNHKNIISLLNVFTPQKTLEEFQDVYLVM 146
Query: 263 EFAEHDLLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTV 322
E + +L Q+I E+ + +++Q+L G+ +LH I+HRDLKP+NI+V
Sbjct: 147 ELMDANLCQVIQMELDHER-------MSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKS 199
Query: 323 DGCVKIGDLGLARKFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFA 382
D +KI D GLAR T + +VT +YRAPE+ILG Y +D+W+VGCI
Sbjct: 200 DCTLKILDFGLAR----TAGTSFMMTPYVVTRYYRAPEVILG-MGYKENVDIWSVGCIMG 254
Query: 383 ELIGLRPIFKGEEAKMESKKSVLFQANQFQKILEVMGSP----DHKIWPNIDSY----PE 434
E++ + +F G + +Q+ K++E +G+P K+ P + +Y P+
Sbjct: 255 EMVRHKILFPGRD-----------YIDQWNKVIEQLGTPCPEFMKKLQPTVRNYVENRPK 303
Query: 435 YLQLAKMPKYRDNL-TAWYQTAGGKDKTALDILYRLLQYDPIKRIDAIDALDHVY 488
Y L + D+L A + K A D+L ++L DP KRI DAL H Y
Sbjct: 304 YAGLTFPKLFPDSLFPADSEHNKLKASQARDLLSKMLVIDPAKRISVDDALQHPY 358
>Hs20986510 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 464
Score = 126 bits (317), Expect = 8e-29
Identities = 92/295 (31%), Positives = 151/295 (51%), Gaps = 42/295 (14%)
Query: 209 AIKKFKTEREGVEHYTGISQSACREMSLCRELDNNHLTKLVEIFLEKKS------IYMVS 262
AIKK + H ++ A RE+ L + +++ ++ L+ +F +K+ +Y+V
Sbjct: 91 AIKKLSRPFQNQTH----AKRAYRELVLMKCVNHKNIISLLNVFTPQKTLEEFQDVYLVM 146
Query: 263 EFAEHDLLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTV 322
E + +L Q+I E+ + +++Q+L G+ +LH I+HRDLKP+NI+V
Sbjct: 147 ELMDANLCQVIQMELDHER-------MSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKS 199
Query: 323 DGCVKIGDLGLARKFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFA 382
D +KI D GLAR T + +VT +YRAPE+ILG Y +D+W+VGCI
Sbjct: 200 DCTLKILDFGLAR----TAGTSFMMTPYVVTRYYRAPEVILG-MGYKENVDIWSVGCIMG 254
Query: 383 ELIGLRPIFKGEEAKMESKKSVLFQANQFQKILEVMGSP----DHKIWPNIDSY----PE 434
E++ + +F G + +Q+ K++E +G+P K+ P + +Y P+
Sbjct: 255 EMVRHKILFPGRD-----------YIDQWNKVIEQLGTPCPEFMKKLQPTVRNYVENRPK 303
Query: 435 YLQLAKMPKYRDNL-TAWYQTAGGKDKTALDILYRLLQYDPIKRIDAIDALDHVY 488
Y L + D+L A + K A D+L ++L DP KRI DAL H Y
Sbjct: 304 YAGLTFPKLFPDSLFPADSEHNKLKASQARDLLSKMLVIDPAKRISVDDALQHPY 358
>Hs20986506 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 426
Score = 126 bits (317), Expect = 8e-29
Identities = 92/295 (31%), Positives = 151/295 (51%), Gaps = 42/295 (14%)
Query: 209 AIKKFKTEREGVEHYTGISQSACREMSLCRELDNNHLTKLVEIFLEKKS------IYMVS 262
AIKK + H ++ A RE+ L + +++ ++ L+ +F +K+ +Y+V
Sbjct: 53 AIKKLSRPFQNQTH----AKRAYRELVLMKCVNHKNIISLLNVFTPQKTLEEFQDVYLVM 108
Query: 263 EFAEHDLLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTV 322
E + +L Q+I E+ + +++Q+L G+ +LH I+HRDLKP+NI+V
Sbjct: 109 ELMDANLCQVIQMELDHER-------MSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKS 161
Query: 323 DGCVKIGDLGLARKFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFA 382
D +KI D GLAR T + +VT +YRAPE+ILG Y +D+W+VGCI
Sbjct: 162 DCTLKILDFGLAR----TAGTSFMMTPYVVTRYYRAPEVILG-MGYKENVDIWSVGCIMG 216
Query: 383 ELIGLRPIFKGEEAKMESKKSVLFQANQFQKILEVMGSP----DHKIWPNIDSY----PE 434
E++ + +F G + +Q+ K++E +G+P K+ P + +Y P+
Sbjct: 217 EMVRHKILFPGRD-----------YIDQWNKVIEQLGTPCPEFMKKLQPTVRNYVENRPK 265
Query: 435 YLQLAKMPKYRDNL-TAWYQTAGGKDKTALDILYRLLQYDPIKRIDAIDALDHVY 488
Y L + D+L A + K A D+L ++L DP KRI DAL H Y
Sbjct: 266 YAGLTFPKLFPDSLFPADSEHNKLKASQARDLLSKMLVIDPAKRISVDDALQHPY 320
>ECU11g0960 [D] KOG0600 Cdc2-related protein kinase
Length = 329
Score = 126 bits (317), Expect = 8e-29
Identities = 85/287 (29%), Positives = 143/287 (49%), Gaps = 40/287 (13%)
Query: 208 YAIKKFKTEREGVEHYTGISQSACREMSLCRELDNNHLTKLVEIFLEKKS-IYMVSEFAE 266
YA+KK E+EG +S + RE+ + R + + + +L+E+ +E IYMV +
Sbjct: 46 YALKKVSKEKEG------LSVTTIREVQVLRAMGHPSIVRLIEVVVEPGGDIYMVFPYFP 99
Query: 267 HDLLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGCV 326
+DL + I + + +K I +QI GV Y+H I+HRDLK ANI++
Sbjct: 100 YDLNRFIRSNK------MTCSEIKHIFYQIAQGVCYIHSKGIMHRDLKSANILLDQKLNA 153
Query: 327 KIGDLGLARKFNNMVQTLYTGDKV--IVTIWYRAPELILGARHYTPAIDLWAVGCIFAEL 384
I D G+AR T TG +VT+WYRAPE++LG+ YT A+D+W++GCI E+
Sbjct: 154 SIADFGMAR------YTTKTGAYTPGMVTLWYRAPEILLGSSSYTYAVDIWSLGCILTEM 207
Query: 385 IGLRPIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEY--LQLAKMP 442
IF+G + Q + ++ GS + +P + P + +L + P
Sbjct: 208 YLGHMIFQGSTEML-----------QLEMVIHACGSINENSYPGVQDLPGFRNFRLPQSP 256
Query: 443 KYRDNLTAWYQTAGGKDKTALDILYRLLQYDPIKRIDAIDALDHVYF 489
+ + + + D +A++++ ++L DP KRI + YF
Sbjct: 257 RRIEGIIRKH------DASAVELVSKMLCLDPSKRITVEQVVGSKYF 297
>CE27574 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 463
Score = 126 bits (316), Expect = 1e-28
Identities = 97/298 (32%), Positives = 151/298 (50%), Gaps = 48/298 (16%)
Query: 209 AIKKFKTEREGVEHYTGISQSACREMSLCRELDNNHLTKLVEIFLEKKSI------YMVS 262
AIKK + V H ++ A RE+ L +++ ++ ++ F +K + Y+V
Sbjct: 146 AIKKLSRPFQNVTH----AKRAYRELKLMSLVNHKNIIGILNCFTPQKKLDEFNDLYIVM 201
Query: 263 EFAEHDLLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTV 322
E + +L Q+I E+ L +++Q+L G+ +LH I+HRDLKP+NI+V
Sbjct: 202 ELMDANLCQVIQMDLDHER-------LSYLLYQMLCGIRHLHSAGIIHRDLKPSNIVVRS 254
Query: 323 DGCVKIGDLGLAR-KFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIF 381
D +KI D GLAR + T Y +VT +YRAPE+ILG Y +D+W++GCIF
Sbjct: 255 DCTLKILDFGLARTAIEAFMMTPY-----VVTRYYRAPEVILG-MGYKENVDVWSIGCIF 308
Query: 382 AELIGLRPIFKGEEAKMESKKSVLFQANQFQKILEVMGSPD----HKIWPNIDSY----P 433
ELI R +F G + +Q+ +I+E +G+PD ++ P + +Y P
Sbjct: 309 GELIRGRVLFPGGD-----------HIDQWTRIIEQLGTPDRSFLERLQPTVRNYVENRP 357
Query: 434 EYLQLAKMPKYRDNLTAWYQTAGGKDKT---ALDILYRLLQYDPIKRIDAIDALDHVY 488
Y + DN+ + TA T A D+L R+L DP +RI DAL H Y
Sbjct: 358 RYQATPFEVLFSDNM--FPMTADSSRLTGAQARDLLSRMLVIDPERRISVDDALRHPY 413
>CE20258 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 353
Score = 125 bits (315), Expect = 1e-28
Identities = 97/352 (27%), Positives = 161/352 (45%), Gaps = 63/352 (17%)
Query: 206 QFYAIKKFKTEREGVEHYTGISQSACREMSLCRELDNNHLTKLVEIFLEKKSIYMVSEFA 265
Q AIKKF E E H I + A RE+ + ++L + +L L+E+F + +++V E
Sbjct: 28 QIVAIKKF-VETEDDPH---IKKIALREIRMLKQLKHQNLVGLIEVFKRNRKLHLVFELC 83
Query: 266 EHDLLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGC 325
+ +L + + H + ++K I++Q+L+ + + H + +HRD+KP NI +T +
Sbjct: 84 DRTVLHELEKNPHG----VNDELIKKIIYQLLEALKFCHSHKCIHRDVKPENIFLTRNDQ 139
Query: 326 VKIGDLGLARKFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELI 385
VK+GD G AR N +YT + T WYR+PEL++G Y P +D+WAVGC++AEL+
Sbjct: 140 VKLGDFGFARIINTT--EMYTD--YVATRWYRSPELLVGDVQYGPPVDIWAVGCVYAELL 195
Query: 386 GLRPIFKGEE------------AKMESKKSVLFQANQFQKILEVMGSPDHKIWPNIDSYP 433
++ G + + +F+ NQF L S P
Sbjct: 196 TGEALWPGRSDIDQLYHIRKTLGEFLPRHISIFRTNQFFFGL---------------SIP 240
Query: 434 EYLQLAKMPKYRDNLTAWYQTAGGKDKTALDILYRLLQYDPIKRIDAIDALDHVYFTNGD 493
E L +P N ++ LD L + + P +R + + H F+N
Sbjct: 241 EPEHLEPLPSKLPNASS----------AQLDFLQKCFEMSPDRRFSCSELMLHGIFSNWI 290
Query: 494 PPV--CENVFEGLNYKYPPR---RIHTNDNDIT---------NVGNDNNQAN 531
+ E+ GL K P ++ N N++ N GN+NN N
Sbjct: 291 LRIRQDESTPTGLTSKRSPNYLPLLNGNSNNLVSKNFSLQGGNHGNNNNNGN 342
>At2g01450 [T] KOG0660 Mitogen-activated protein kinase
Length = 516
Score = 125 bits (315), Expect = 1e-28
Identities = 98/319 (30%), Positives = 151/319 (46%), Gaps = 33/319 (10%)
Query: 209 AIKKFKTEREGVEHYTGISQSACREMSLCRELDNNHLTKLVEIFL-----EKKSIYMVSE 263
AIKK E V I RE+ L R L + + ++ I L E K IY+V E
Sbjct: 43 AIKKMTNVFEHVSDAIRI----LREIKLLRLLRHPDIVEIKHIMLPPCRKEFKDIYVVFE 98
Query: 264 FAEHDLLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVD 323
E DL ++ + + P+ + ++Q+L G+ ++H + HRDLKP NI+ D
Sbjct: 99 LMESDLHHVLKVNDD-----LTPQHHQFFLYQLLRGLKFMHSAHVFHRDLKPKNILANAD 153
Query: 324 GCVKIGDLGLAR-KFNNMVQTLYTGDKVIVTIWYRAPELILG-ARHYTPAIDLWAVGCIF 381
+KI DLGLAR F + ++ D + T WYRAPEL +YTPAID+W+VGCIF
Sbjct: 154 CKIKICDLGLARVSFTDSPSAVFWTD-YVATRWYRAPELCGSFYSNYTPAIDMWSVGCIF 212
Query: 382 AELIGLRPIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKM 441
AE++ +P+F G+ +Q + + +++G+P I + L M
Sbjct: 213 AEMLTGKPLFPGKNV-----------VHQLELVTDLLGTPSPITLSRIRNEKARKYLGNM 261
Query: 442 PKYRDNLTAWYQTAGGKDKTALDILYRLLQYDPIKRIDAIDALDHVYF---TNGDPPVCE 498
R + + D AL +L RL+ +DP R A +AL YF N D
Sbjct: 262 --RRKDPVPFTHKFPNIDPVALKLLQRLIAFDPKDRPSAEEALADPYFQGLANVDYEPSR 319
Query: 499 NVFEGLNYKYPPRRIHTND 517
L +++ R++ +D
Sbjct: 320 QPISKLEFEFERRKLTRDD 338
>YPR054w [T] KOG0660 Mitogen-activated protein kinase
Length = 388
Score = 125 bits (314), Expect = 2e-28
Identities = 78/253 (30%), Positives = 128/253 (49%), Gaps = 33/253 (13%)
Query: 258 IYMVSEFAEHDLLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPAN 317
+Y E ++DL ++IH + +K ++QIL G+ Y+H ++HRDLKP N
Sbjct: 117 LYCYQELIDYDLAKVIHSSVQ-----LSEFHIKYFLYQILCGLKYIHSADVIHRDLKPGN 171
Query: 318 IMVTVDGCVKIGDLGLAR-------KFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTP 370
I+ T++GC+KI D GLAR K ++ VQ T + T WYRAPEL+L + Y+
Sbjct: 172 ILCTLNGCLKICDFGLARGIHAGFFKCHSTVQPHIT--NYVATRWYRAPELLLSNQPYSK 229
Query: 371 AIDLWAVGCIFAELIGLRPIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHKIWPNID 430
++D+WAVGCI AE +P+F G ++ +Q +I++V+G+PD I
Sbjct: 230 SVDIWAVGCILAEFYARKPVFMGRDS-----------MHQIFEIIKVLGTPDKDILIKFG 278
Query: 431 SYPEYL--QLAKMPKYRDNLTAWYQTAGGKDKTALDILYRLLQYDPIKRIDAIDALDHVY 488
+ + + + P Y+ W A++++ LL +D R++ A+ H +
Sbjct: 279 TIKAWNLGKNSNNPVYKK--IPWSNIFPFASHEAINLIESLLHWDSTHRLNVEQAISHPF 336
Query: 489 FTN----GDPPVC 497
D PVC
Sbjct: 337 LNEVRKPDDEPVC 349
>At5g19010 [T] KOG0660 Mitogen-activated protein kinase
Length = 567
Score = 125 bits (314), Expect = 2e-28
Identities = 93/287 (32%), Positives = 138/287 (47%), Gaps = 28/287 (9%)
Query: 209 AIKKFKTEREGVEHYTGISQSACREMSLCRELDNNHLTKLVEIFL-----EKKSIYMVSE 263
AIKK E V T I RE+ L R L + + ++ I L E + IY+V E
Sbjct: 52 AIKKINDIFEHVSDATRI----LREIKLLRLLRHPDIVEIKHILLPPSRREFRDIYVVFE 107
Query: 264 FAEHDLLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVD 323
E DL Q+I + + P + ++Q+L G+ Y+H + HRDLKP NI+ D
Sbjct: 108 LMESDLHQVIKANDD-----LTPEHYQFFLYQLLRGLKYIHTANVFHRDLKPKNILANAD 162
Query: 324 GCVKIGDLGLARKFNNMVQTLYTGDKVIVTIWYRAPELILG-ARHYTPAIDLWAVGCIFA 382
+KI D GLAR N T + T WYRAPEL YTPAID+W++GCIFA
Sbjct: 163 CKLKICDFGLARVAFNDTPTAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIGCIFA 222
Query: 383 ELIGLRPIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMP 442
EL+ +P+F G+ +Q + +++G+P + + + L+ M
Sbjct: 223 ELLTGKPLFPGKNV-----------VHQLDLMTDMLGTPSAEAIGRVRNEKARRYLSSMR 271
Query: 443 KYRDNLTAWYQTAGGKDKTALDILYRLLQYDPIKRIDAIDALDHVYF 489
K + + D AL +L ++L ++P R A +AL VYF
Sbjct: 272 KKKP--IPFSHKFPHTDPLALRLLEKMLSFEPKDRPTAEEALADVYF 316
>At3g18040 [T] KOG0660 Mitogen-activated protein kinase
Length = 613
Score = 125 bits (314), Expect = 2e-28
Identities = 118/401 (29%), Positives = 176/401 (43%), Gaps = 49/401 (12%)
Query: 129 SVSADSNLDINSIN--RSTRQQEANDNLTTMDFRKPSHKRFTPPNNSNSTQIRSNSGSEX 186
S S + D++ +N R +R+ N MD P K FT ++ QI+ G
Sbjct: 85 SFSLVRDFDLSGLNCIRVSRR-----NYILMD---PHKKFFTEYGEASRYQIQEVIGKGS 136
Query: 187 XXXXXXXXXXXXXXKPSQIQFYAIKKFKTEREGVEHYTGISQSACREMSLCRELDNNHLT 246
K AIKK E V T I RE+ L R L + +
Sbjct: 137 YGVVASAIDTHSGEK------VAIKKINDVFEHVSDATRI----LREIKLLRLLRHPDIV 186
Query: 247 KLVEIFL-----EKKSIYMVSEFAEHDLLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVS 301
++ + L E + IY+V E E DL Q+I + + P + ++Q+L G+
Sbjct: 187 EIKHVMLPPSRREFRDIYVVFELMESDLHQVIKANDD-----LTPEHYQFFLYQLLRGLK 241
Query: 302 YLHQNWILHRDLKPANIMVTVDGCVKIGDLGLAR-KFNNMVQTLYTGDKVIVTIWYRAPE 360
++H + HRDLKP NI+ D +KI D GLAR FN+ ++ D V T WYRAPE
Sbjct: 242 FIHTANVFHRDLKPKNILANSDCKLKICDFGLARVSFNDAPSAIFWTDYV-ATRWYRAPE 300
Query: 361 LILG-ARHYTPAIDLWAVGCIFAELIGLRPIFKGEEAKMESKKSVLFQANQFQKILEVMG 419
L YTPAID+W++GCIFAE++ +P+F G+ +Q + +++G
Sbjct: 301 LCGSFFSKYTPAIDIWSIGCIFAEMLTGKPLFPGKNV-----------VHQLDIMTDLLG 349
Query: 420 SPDHKIWPNIDSYPEYLQLAKMPKYRDNLTAWYQTAGGKDKTALDILYRLLQYDPIKRID 479
+P + I + L M R + D AL +L+RLL +DP R
Sbjct: 350 TPPPEAIARIRNEKARRYLGNM--RRKPPVPFTHKFPHVDPLALRLLHRLLAFDPKDRPS 407
Query: 480 AIDALDHVYF---TNGDPPVCENVFEGLNYKYPPRRIHTND 517
A +AL YF N D L +++ R+I D
Sbjct: 408 AEEALADPYFYGLANVDREPSTQPIPKLEFEFERRKITKED 448
>At1g54610 [D] KOG0600 Cdc2-related protein kinase
Length = 572
Score = 124 bits (311), Expect = 4e-28
Identities = 89/283 (31%), Positives = 141/283 (49%), Gaps = 27/283 (9%)
Query: 232 REMSLCRELDNNHLTKLVEIFLEKKS--IYMVSEFAEHDLLQIIHFHSHPEKRLIPPRML 289
RE+ + R LD+ ++ KL + + S +Y+V ++ +HDL + S P + +
Sbjct: 164 REILVLRRLDHPNVVKLEGLVTSRMSCSLYLVFQYMDHDLAGLA---SSPVVKFSESEV- 219
Query: 290 KSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGCVKIGDLGLARKFNNMVQTLYTGDK 349
K +M Q++ G+ + H +LHRD+K +N+++ G +KI D GLA F+ + T
Sbjct: 220 KCLMRQLISGLEHCHSRGVLHRDIKGSNLLIDDGGVLKIADFGLATIFDPNHKRPMTSR- 278
Query: 350 VIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELIGLRPIFKGEEAKMESKKSVLFQAN 409
+VT+WYRAPEL+LGA Y IDLW+ GCI AEL+ RPI G +
Sbjct: 279 -VVTLWYRAPELLLGATDYGVGIDLWSAGCILAELLAGRPIMPGRT-----------EVE 326
Query: 410 QFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPKYRDNLTAWYQTAGGKDKTALDILYRL 469
Q KI ++ GSP W + + P Y+ ++ +T ++L ++ L
Sbjct: 327 QLHKIYKLCGSPSEDYWKKGKFTHGAIYKPREP-YKRSIR---ETFKDFPPSSLPLIDAL 382
Query: 470 LQYDPIKRIDAIDALDHVYFTNGDPPVCENVFEGLNYKYPPRR 512
L +P R A AL +FT+ +P CE KYPP +
Sbjct: 383 LSIEPEDRQTASAALKSEFFTS-EPYACEPADLP---KYPPSK 421
>ECU08g1790 [D] KOG0600 Cdc2-related protein kinase
Length = 309
Score = 124 bits (310), Expect = 5e-28
Identities = 71/217 (32%), Positives = 118/217 (53%), Gaps = 27/217 (12%)
Query: 208 YAIKKFKTEREGVEHYTGISQSACREMSLCRELDNNHLTKLVEIFLEKKSIYMVSEFAEH 267
+AIKK +RE TG +A RE+ LC+ + N H+ L EI E+ I++V E+ +
Sbjct: 30 FAIKKMPVDRE-----TGFPFTAIREIKLCKSVINKHIIGLDEIVFEEGFIFVVLEYMPY 84
Query: 268 DLLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGCVK 327
DL ++ + + ++SI Q+++ VS +H ++HRD+KP+NI++ G +K
Sbjct: 85 DLTGLLASGAK-----LSTDQIRSITSQLIEAVSSMHGMGLVHRDIKPSNILLDCHGMLK 139
Query: 328 IGDLGLARKFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELIGL 387
+ D GL R+ + M+ + T+WYRAPEL+LG Y+ +D W+VGCI E+
Sbjct: 140 LTDFGLTREISGMMTNR------VCTLWYRAPELLLGETSYSLKVDAWSVGCIMLEMRLG 193
Query: 388 RPIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHK 424
RP ++G + + +Q + I E +G P K
Sbjct: 194 RPPYRGSD-----------EVSQIKLIFEELGIPQDK 219
>CE28918 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 406
Score = 123 bits (309), Expect = 7e-28
Identities = 86/290 (29%), Positives = 146/290 (49%), Gaps = 39/290 (13%)
Query: 208 YAIKKFKTEREGVEHYTGISQSACREMSLCRELDNN---HLTKLVEIFLEKK------SI 258
YA+K+ + GI QS RE+++ + L ++ L +F + I
Sbjct: 128 YALKQIMISSKN----EGIPQSVLREITVMKHLARKAHPNIISLKSVFHQLDPVRAILKI 183
Query: 259 YMVSEFAEHDLLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANI 318
M+ E + DL H R +P + K + QI+ + +LH + I+HRDLKP NI
Sbjct: 184 NMIMERCDWDL----HTFLRNIPRGVPEQQAKHVTAQIVRALDFLHTHSIIHRDLKPQNI 239
Query: 319 MVTVDGCVKIGDLGLARKFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVG 378
++ D VK+ D GL+++++N T +T ++VT+WYR+PE++L + +Y +D+WA+G
Sbjct: 240 LLNRDQTVKLADFGLSKEYSN--TTAFT--TLVVTLWYRSPEVLLQS-YYNSTVDMWALG 294
Query: 379 CIFAELIGLRPIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQL 438
CI +E+ +P+F G+ +A Q I + MG+P K WP+ +
Sbjct: 295 CIVSEIYCRQPLFVGQN-----------EAEQLTDIFKKMGTPVGKDWPS----ESVIAR 339
Query: 439 AKMPKYRDNLTAWYQTAGGKDKTALDILYRLLQYDPIKRIDAIDALDHVY 488
P+YR T + K A++ + + L+YD KR+ A AL H +
Sbjct: 340 DSFPQYRP--TNLKDLSPQMSKQAIEFVQQCLRYDHSKRLSARGALSHPF 387
>CE18608 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 342
Score = 123 bits (309), Expect = 7e-28
Identities = 86/290 (29%), Positives = 146/290 (49%), Gaps = 39/290 (13%)
Query: 208 YAIKKFKTEREGVEHYTGISQSACREMSLCRELDNN---HLTKLVEIFLEKK------SI 258
YA+K+ + GI QS RE+++ + L ++ L +F + I
Sbjct: 64 YALKQIMISSKN----EGIPQSVLREITVMKHLARKAHPNIISLKSVFHQLDPVRAILKI 119
Query: 259 YMVSEFAEHDLLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANI 318
M+ E + DL H R +P + K + QI+ + +LH + I+HRDLKP NI
Sbjct: 120 NMIMERCDWDL----HTFLRNIPRGVPEQQAKHVTAQIVRALDFLHTHSIIHRDLKPQNI 175
Query: 319 MVTVDGCVKIGDLGLARKFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVG 378
++ D VK+ D GL+++++N T +T ++VT+WYR+PE++L + +Y +D+WA+G
Sbjct: 176 LLNRDQTVKLADFGLSKEYSN--TTAFT--TLVVTLWYRSPEVLLQS-YYNSTVDMWALG 230
Query: 379 CIFAELIGLRPIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQL 438
CI +E+ +P+F G+ +A Q I + MG+P K WP+ +
Sbjct: 231 CIVSEIYCRQPLFVGQN-----------EAEQLTDIFKKMGTPVGKDWPS----ESVIAR 275
Query: 439 AKMPKYRDNLTAWYQTAGGKDKTALDILYRLLQYDPIKRIDAIDALDHVY 488
P+YR T + K A++ + + L+YD KR+ A AL H +
Sbjct: 276 DSFPQYRP--TNLKDLSPQMSKQAIEFVQQCLRYDHSKRLSARGALSHPF 323
>At5g50860 [D] KOG0600 Cdc2-related protein kinase
Length = 580
Score = 123 bits (309), Expect = 7e-28
Identities = 87/283 (30%), Positives = 139/283 (48%), Gaps = 27/283 (9%)
Query: 232 REMSLCRELDNNHLTKLVEIFLEKKS--IYMVSEFAEHDLLQIIHFHSHPEKRLIPPRML 289
RE+ + R L++ ++ KL + + S +Y+V E+ EHDL + + K +P +
Sbjct: 160 REILVLRRLNHPNVIKLQGLVTSRVSCSLYLVFEYMEHDLSGLAA--TQGLKFDLP--QV 215
Query: 290 KSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGCVKIGDLGLARKFNNMVQTLYTGDK 349
K M Q+L G+ + H +LHRD+K +N+++ DG +KI D GLA ++ + T
Sbjct: 216 KCFMKQLLSGLEHCHSRGVLHRDIKGSNLLIDNDGILKIADFGLATFYDPKQKQTMTSR- 274
Query: 350 VIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELIGLRPIFKGEEAKMESKKSVLFQAN 409
+VT+WYR PEL+LGA Y +DLW+ GCI AEL+ +P+ G +
Sbjct: 275 -VVTLWYRPPELLLGATSYGTGVDLWSAGCIMAELLAGKPVMPGRT-----------EVE 322
Query: 410 QFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPKYRDNLTAWYQTAGGKDKTALDILYRL 469
Q KI ++ GSP W L + P R A+ G +++ ++ L
Sbjct: 323 QLHKIFKLCGSPSDSYWKKYRLPNATLFKPQHPYKRCVAEAF----NGFTPSSVHLVETL 378
Query: 470 LQYDPIKRIDAIDALDHVYFTNGDPPVCENVFEGLNYKYPPRR 512
L DP R + AL+ +FT +P C+ KYPP +
Sbjct: 379 LTIDPADRGTSTSALNSEFFTT-EPLPCD---PSSLPKYPPSK 417
>7297009 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 392
Score = 123 bits (309), Expect = 7e-28
Identities = 88/286 (30%), Positives = 134/286 (46%), Gaps = 32/286 (11%)
Query: 209 AIKKFKTEREGVEHYTGISQSACREMSLCRELDNNHLTKLVEIFLEKKSIYMVSEFAEHD 268
A+K+F + I + A RE+ L + L + +L L+E+F K+ +++V EF E
Sbjct: 31 AVKRFVESEDD----PAIRKIALREIRLLKNLKHPNLVSLLEVFRRKRRLHLVFEFCE-- 84
Query: 269 LLQIIH-FHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGCVK 327
L ++H HP+ P + K I +Q L GV+Y H+ LHRD+KP NI++T G VK
Sbjct: 85 -LTVLHELERHPQG--CPEHLTKQICYQTLLGVAYCHKQGCLHRDIKPENILLTAQGQVK 141
Query: 328 IGDLGLARKFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELIGL 387
+ D G AR M+ + T WYRAPEL++G Y +D+WA+GC+FAEL+
Sbjct: 142 LCDFGFAR----MLSPGENYTDYVATRWYRAPELLVGDTQYGTPVDVWAIGCLFAELVRG 197
Query: 388 RPIFKGEEAKMESKKSVLFQANQFQKILEVMGS--PDHKIWPNIDSYPEYLQ--LAKMPK 443
++ G +Q I + +G P H I EY + +P
Sbjct: 198 EALWPGRS-----------DVDQLYLIRKTLGDLLPRH---IQIFGQNEYFKGITLPVPP 243
Query: 444 YRDNLTAWYQTAGGKDKTALDILYRLLQYDPIKRIDAIDALDHVYF 489
+ L ++ +D L + L DP KR H YF
Sbjct: 244 TLEPLEDKMPAKSQQNPLTIDFLKKCLDKDPTKRWSCEKLTKHSYF 289
>SPAC31G5.09c [T] KOG0660 Mitogen-activated protein kinase
Length = 372
Score = 123 bits (308), Expect = 9e-28
Identities = 80/263 (30%), Positives = 134/263 (50%), Gaps = 26/263 (9%)
Query: 232 REMSLCRELDNNHLTKLVEI-----FLEKKSIYMVSEFAEHDLLQIIHFHSHPEKRLIPP 286
RE+ L R + ++ +++I + E + +Y+V E E DL ++I S P +
Sbjct: 84 REIKLLRHFRHENIISILDILPPPSYQELEDVYIVQELMETDLYRVIR--SQP----LSD 137
Query: 287 RMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGCVKIGDLGLARKFNNMVQTLYT 346
+ +QIL + +H ++HRDLKP+N+++ + +K+ D GLAR
Sbjct: 138 DHCQYFTYQILRALKAMHSAGVVHRDLKPSNLLLNANCDLKVADFGLARSTTAQGGNPGF 197
Query: 347 GDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELIGLRPIFKGEEAKMESKKSVLF 406
+ + T WYRAPE++L R Y+ AIDLW+ GCI AE++ RP+F G++
Sbjct: 198 MTEYVATRWYRAPEIMLSFREYSKAIDLWSTGCILAEMLSARPLFPGKD----------- 246
Query: 407 QANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMP-KYRDNLTAWYQTAGGKDKTALDI 465
+Q IL ++G+P + I S + +P + + A + A A+D+
Sbjct: 247 YHSQITLILNILGTPTMDDFSRIKSARARKYIKSLPFTPKVSFKALFPQA---SPDAIDL 303
Query: 466 LYRLLQYDPIKRIDAIDALDHVY 488
L +LL ++P KRI A +AL H Y
Sbjct: 304 LEKLLTFNPDKRITAEEALKHPY 326
>YKL161c [T] KOG0660 Mitogen-activated protein kinase
Length = 433
Score = 122 bits (305), Expect = 2e-27
Identities = 78/238 (32%), Positives = 127/238 (52%), Gaps = 27/238 (11%)
Query: 258 IYMVSEFAEHDLLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPAN 317
+Y+ E E DL QII E+RL +S ++QIL + Y+H +LH DLKP N
Sbjct: 104 VYLYEELMECDLSQIIR----SEQRLEDAHF-QSFIYQILCALKYIHSANVLHCDLKPKN 158
Query: 318 IMVTVDGCVKIGDLGLARKF--NNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLW 375
++V D +KI + GL+ + N+ V + I +IWY+APE++L + T A+D+W
Sbjct: 159 LLVNSDCQLKICNFGLSCSYSENHKVNDGFIKG-YITSIWYKAPEILLNYQECTKAVDIW 217
Query: 376 AVGCIFAELIGLRPIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEY 435
+ GCI AEL+G +P+F+G++ + IL+++G+P + I S Y
Sbjct: 218 STGCILAELLGRKPMFEGKD-----------YVDHLNHILQILGTPPEETLQEIASQKVY 266
Query: 436 ---LQLAKMPKYRDNLTAWYQTAGGKDKTALDILYRLLQYDPIKRIDAIDALDHVYFT 490
Q +P ++ G + AL++L ++L++DP KRI DAL+H Y +
Sbjct: 267 NYIFQFGNIPG-----RSFESILPGANPEALELLKKMLEFDPKKRITVEDALEHPYLS 319
>YGR040w [T] KOG0660 Mitogen-activated protein kinase
Length = 368
Score = 121 bits (304), Expect = 3e-27
Identities = 87/287 (30%), Positives = 146/287 (50%), Gaps = 28/287 (9%)
Query: 232 REMSLCRELDNNH-----LTKLVEIFLEK-KSIYMVSEFAEHDLLQIIHFHSHPEKRLIP 285
RE+ L R + L K+ + ++K ++Y+V E E DL ++I+ + L
Sbjct: 58 REIKLLRYFHEHENIISILDKVRPVSIDKLNAVYLVEELMETDLQKVINNQNSGFSTLSD 117
Query: 286 PRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGCVKIGDLGLARKFNNMVQTLY 345
+ + +QIL + +H ++HRD+KP+N+++ + +K+ D GLAR + +
Sbjct: 118 DHV-QYFTYQILRALKSIHSAQVIHRDIKPSNLLLNSNCDLKVCDFGLARCLASSSDSRE 176
Query: 346 T----GDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELIGLRPIFKGEEAKMESK 401
T + + T WYRAPE++L + YT A+D+W+ GCI AE++ +P+F G +
Sbjct: 177 TLVGFMTEYVATRWYRAPEIMLTFQEYTTAMDIWSCGCILAEMVSGKPLFPGRD------ 230
Query: 402 KSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPKYRDNL---TAWYQTAGGK 458
+Q ILEV+G+P + + I S +A +P R L T W +T
Sbjct: 231 -----YHHQLWLILEVLGTPSFEDFNQIKSKRAKEYIANLP-MRPPLPWETVWSKTDLNP 284
Query: 459 DKTALDILYRLLQYDPIKRIDAIDALDHVYFTNGDPPVCENVFEGLN 505
D +D+L ++LQ++P KRI A +AL H Y P E + LN
Sbjct: 285 D--MIDLLDKMLQFNPDKRISAAEALRHPYLAMYHDPSDEPEYPPLN 329
>Hs4506089 [T] KOG0660 Mitogen-activated protein kinase
Length = 557
Score = 121 bits (304), Expect = 3e-27
Identities = 96/321 (29%), Positives = 152/321 (46%), Gaps = 51/321 (15%)
Query: 230 ACREMSLCRELDNNHLTKLVEIF----------LEKKSI-YMVSEFAEHDLLQIIHFHSH 278
A RE+ + R LD++++ K+ E+ L K S+ Y+V E+ E DL +++
Sbjct: 62 ALREIKIIRRLDHDNIVKVYEVLGPKGTDLQGELFKFSVAYIVQEYMETDLARLL----- 116
Query: 279 PEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGCV-KIGDLGLARKF 337
E+ + K M+Q+L G+ Y+H +LHRDLKPANI ++ + V KIGD GLAR
Sbjct: 117 -EQGTLAEEHAKLFMYQLLRGLKYIHSANVLHRDLKPANIFISTEDLVLKIGDFGLARIV 175
Query: 338 NNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELIGLRPIFKGEEAK 397
+ + +VT WYR+P L+L +YT AID+WA GCI AE++ R +F G
Sbjct: 176 DQHYSHKGYLSEGLVTKWYRSPRLLLSPNNYTKAIDMWAAGCILAEMLTGRMLFAGAH-- 233
Query: 398 MESKKSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPKYRDNLTAWY----- 452
+ Q Q ILE + P I + L MP + + W
Sbjct: 234 ---------ELEQMQLILETI--------PVIREEDKDELLRVMPSFVSS--TWEVKRPL 274
Query: 453 -QTAGGKDKTALDILYRLLQYDPIKRIDAIDALDHVYFTNGDPPVCENVFEGLNYKYPPR 511
+ + A+D L ++L ++P+ R+ A L H Y + P E + P
Sbjct: 275 RKLLPEVNSEAIDFLEKILTFNPMDRLTAEMGLQHPYMSPYSCPEDEPTSQ------HPF 328
Query: 512 RIHTNDNDITNVGNDNNQANH 532
RI +DI + + +Q ++
Sbjct: 329 RIEDEIDDIVLMAANQSQLSN 349
>Hs4505569 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 493
Score = 120 bits (302), Expect = 4e-27
Identities = 83/283 (29%), Positives = 145/283 (50%), Gaps = 28/283 (9%)
Query: 209 AIKKFKTEREGVEHYTGISQSACREMSLCRELDNNHLTKLVEIFLEKKSIYMVSEFAEHD 268
AIKKF + + + A RE+ L ++L + +L L+E+ +KK Y+V EF +H
Sbjct: 31 AIKKFLESDDDKM----VKKIAMREIKLLKQLRHENLVNLLEVCKKKKRWYLVFEFVDHT 86
Query: 269 LLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGCVKI 328
+L + + + ++++ ++QI++G+ + H + I+HRD+KP NI+V+ G VK+
Sbjct: 87 ILDDLELFPNG----LDYQVVQKYLFQIINGIGFCHSHNIIHRDIKPENILVSQSGVVKL 142
Query: 329 GDLGLARKFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELIGLR 388
D G AR + +YT + T WYRAPEL++G Y A+D+WA+GC+ E+
Sbjct: 143 CDFGFARTLAAPGE-VYTD--YVATRWYRAPELLVGDVKYGKAVDVWAIGCLVTEMFMGE 199
Query: 389 PIFKGEEAKMESKKSVLFQANQFQKILEVMGS--PDHKIWPNIDSYPEYLQLAKMPKYRD 446
P+F G+ +Q I+ +G+ P H+ N + ++L ++ K R+
Sbjct: 200 PLFPGDS-----------DIDQLYHIMMCLGNLIPRHQELFNKNPVFAGVRLPEI-KERE 247
Query: 447 NLTAWYQTAGGKDKTALDILYRLLQYDPIKRIDAIDALDHVYF 489
L Y + +D+ + L DP KR + L H +F
Sbjct: 248 PLERRYPKL---SEVVIDLAKKCLHIDPDKRPFCAELLHHDFF 287
>Hs4506785 [T] KOG0660 Mitogen-activated protein kinase
Length = 367
Score = 120 bits (301), Expect = 6e-27
Identities = 81/269 (30%), Positives = 142/269 (52%), Gaps = 31/269 (11%)
Query: 227 SQSACREMSLCRELDNNHLTKLVEIFLEKKSI------YMVSEFAEHDLLQIIHFHSHPE 280
++ A RE+ L + + + ++ L+++F +++ Y+V F DL +++ E
Sbjct: 68 AKRAYRELRLLKHMRHENVIGLLDVFTPDETLDDFTDFYLVMPFMGTDLGKLMKHEKLGE 127
Query: 281 KRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGCVKIGDLGLARKFNNM 340
R+ + +++Q+L G+ Y+H I+HRDLKP N+ V D +KI D GLAR+ ++
Sbjct: 128 DRI------QFLVYQMLKGLRYIHAAGIIHRDLKPGNLAVNEDCELKILDFGLARQADSE 181
Query: 341 VQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELIGLRPIFKGEEAKMES 400
+ TG +VT WYRAPE+IL YT +D+W+VGCI AE+I + +FKG +
Sbjct: 182 M----TG--YVVTRWYRAPEVILNWMRYTQTVDIWSVGCIMAEMITGKTLFKGSD----- 230
Query: 401 KKSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPKYRDNLTAWYQTAGGKDK 460
+Q ++I++V G+P + + S + +P+ A T
Sbjct: 231 ------HLDQLKEIMKVTGTPPAEFVQRLQSDEAKNNMKGLPELEKKDFASILT--NASP 282
Query: 461 TALDILYRLLQYDPIKRIDAIDALDHVYF 489
A+++L ++L D +R+ A +AL H YF
Sbjct: 283 LAVNLLEKMLVLDAEQRVTAGEALAHPYF 311
>At1g73670 [T] KOG0660 Mitogen-activated protein kinase
Length = 576
Score = 120 bits (301), Expect = 6e-27
Identities = 92/287 (32%), Positives = 137/287 (47%), Gaps = 28/287 (9%)
Query: 209 AIKKFKTEREGVEHYTGISQSACREMSLCRELDNNHLTKLVEIFL-----EKKSIYMVSE 263
AIKK + + T I RE+ L R L + + ++ I L E + +Y+V E
Sbjct: 117 AIKKINDVFDHISDATRI----LREIKLLRLLLHPDVVEIKHIMLPPSRREFRDVYVVFE 172
Query: 264 FAEHDLLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVD 323
E DL Q+I + + P + ++Q+L G+ Y+H + HRDLKP NI+ D
Sbjct: 173 LMESDLHQVIKANDD-----LTPEHHQFFLYQLLRGLKYVHAANVFHRDLKPKNILANAD 227
Query: 324 GCVKIGDLGLARKFNNMVQTLYTGDKVIVTIWYRAPELILG-ARHYTPAIDLWAVGCIFA 382
+KI D GLAR N T + T WYRAPEL YTPAID+W+VGCIFA
Sbjct: 228 CKLKICDFGLARVSFNDAPTAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSVGCIFA 287
Query: 383 ELIGLRPIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMP 442
E++ +P+F G+ +Q + + +G+P + I + L M
Sbjct: 288 EMLLGKPLFPGKNV-----------VHQLDIMTDFLGTPPPEAISKIRNDKARRYLGNMR 336
Query: 443 KYRDNLTAWYQTAGGKDKTALDILYRLLQYDPIKRIDAIDALDHVYF 489
K + + + D +AL +L RL+ +DP R A +AL YF
Sbjct: 337 KKQP--VPFSKKFPKADPSALRLLERLIAFDPKDRPSAEEALADPYF 381
>At1g53510 [T] KOG0660 Mitogen-activated protein kinase
Length = 603
Score = 120 bits (300), Expect = 8e-27
Identities = 90/265 (33%), Positives = 136/265 (50%), Gaps = 26/265 (9%)
Query: 232 REMSLCRELDNNHLTKLVEIFL-----EKKSIYMVSEFAEHDLLQIIHFHSHPEKRLIPP 286
RE+ L R L + + ++ I L E K IY+V E E DL Q+I + +
Sbjct: 59 REVKLLRLLRHPDIVEIKSIMLPPSKREFKDIYVVFELMESDLHQVIKANDD-----LTR 113
Query: 287 RMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGCVKIGDLGLAR-KFNNMVQTLY 345
+ ++Q+L + ++H + HRDLKP NI+ + +K+ D GLAR FN+ T++
Sbjct: 114 EHHQFFLYQMLRALKFMHTANVYHRDLKPKNILANANCKLKVCDFGLARVAFNDTPTTVF 173
Query: 346 TGDKVIVTIWYRAPELILG-ARHYTPAIDLWAVGCIFAELIGLRPIFKGEEAKMESKKSV 404
D V T WYRAPEL YTPAID+W++GCIFAE++ +P+F G KSV
Sbjct: 174 WTDYV-ATRWYRAPELCGSFFSKYTPAIDVWSIGCIFAEVLTGKPLFPG--------KSV 224
Query: 405 LFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPKYRDNLTAWYQTAGGKDKTALD 464
+ +Q + I +++G+P + + + L +M K N + Q D AL
Sbjct: 225 V---HQLELITDLLGTPKSETISGVRNDKARKYLTEMRK--KNPVTFSQKFSKADPLALR 279
Query: 465 ILYRLLQYDPIKRIDAIDALDHVYF 489
+L RLL +DP R +AL YF
Sbjct: 280 LLQRLLAFDPKDRPTPAEALADPYF 304
>7297631 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 372
Score = 120 bits (300), Expect = 8e-27
Identities = 90/299 (30%), Positives = 149/299 (49%), Gaps = 43/299 (14%)
Query: 206 QFYAIKKFKTEREGVEHYTGISQSACREMSLCRELDNNHLTKLVEIFLEKKS------IY 259
Q AIKK + V H ++ A RE L + +++ ++ L+ F +++ +Y
Sbjct: 48 QNVAIKKLSRPFQNVTH----AKRAYREFKLMKLVNHKNIIGLLNAFTPQRNLEEFQDVY 103
Query: 260 MVSEFAEHDLLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIM 319
+V E + +L Q+I ++ + +++Q+L G+ +LH I+HRDLKP+NI+
Sbjct: 104 LVMELMDANLCQVIQMDLDHDR-------MSYLLYQMLCGIKHLHSAGIIHRDLKPSNIV 156
Query: 320 VTVDGCVKIGDLGLARKFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGC 379
V D +KI D GLAR T + +VT +YRAPE+ILG YT +D+W+VGC
Sbjct: 157 VKADCTLKILDFGLAR----TAGTTFMMTPYVVTRYYRAPEVILG-MGYTENVDIWSVGC 211
Query: 380 IFAELIGLRPIFKGEEAKMESKKSVLFQANQFQKILEVMGSPD----HKIWPNIDSY--- 432
I E+I +F G + +Q+ KI+E +G+P ++ P + +Y
Sbjct: 212 IMGEMIRGGVLFPGTD-----------HIDQWNKIIEQLGTPSPSFMQRLQPTVRNYVEN 260
Query: 433 -PEYLQLAKMPKYRDNL--TAWYQTAGGKDKTALDILYRLLQYDPIKRIDAIDALDHVY 488
P Y + + D L Q + K A ++L ++L DP +RI +AL H Y
Sbjct: 261 RPRYTGYSFDRLFPDGLFPNDNNQNSRRKASDARNLLSKMLVIDPEQRISVDEALKHEY 319
>Hs16936530 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 264
Score = 119 bits (298), Expect = 1e-26
Identities = 81/293 (27%), Positives = 136/293 (45%), Gaps = 69/293 (23%)
Query: 209 AIKKFKTEREGVEHYTGISQSACREMSLCRELDNNHLTKLVEIFLEKKSIYMVSEFAEHD 268
A+KK + + E G+ +A RE+SL +EL++ ++ KL+++ + +Y+V EF D
Sbjct: 31 ALKKIRLDTET----EGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQD 86
Query: 269 LLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGCVKI 328
L + F IP ++KS ++Q+L G+++ H + +LHRDLKP N+++ +G +K+
Sbjct: 87 LKK---FMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKL 143
Query: 329 GDLGLARKFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELIGLR 388
D GLAR F V+T YT + + R
Sbjct: 144 ADFGLARAFGVPVRT-YTHE------------------------------------VTRR 166
Query: 389 PIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPKYRDNL 448
+F G+ + +Q +I +G+PD +WP + S MP Y+ +
Sbjct: 167 ALFPGDS-----------EIDQLFRIFRTLGTPDEVVWPGVTS---------MPDYKPSF 206
Query: 449 TAWYQTAGGK-----DKTALDILYRLLQYDPIKRIDAIDALDHVYFTNGDPPV 496
W + K D+ +L ++L YDP KRI A AL H +F + PV
Sbjct: 207 PKWARQDFSKVVPPLDEDGRSLLSQMLHYDPYKRISAKAALAHPFFQDVTKPV 259
>Hs4506095 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 384
Score = 119 bits (297), Expect = 2e-26
Identities = 91/295 (30%), Positives = 149/295 (49%), Gaps = 42/295 (14%)
Query: 209 AIKKFKTEREGVEHYTGISQSACREMSLCRELDNNHLTKLVEIFLEKKS------IYMVS 262
AIKK + H ++ A RE+ L + +++ ++ L+ +F +KS +Y+V
Sbjct: 53 AIKKLSRPFQNQTH----AKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVM 108
Query: 263 EFAEHDLLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTV 322
E + +L Q+I E+ + +++Q+L G+ +LH I+HRDLKP+NI+V
Sbjct: 109 ELMDANLCQVIQMELDHER-------MSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKS 161
Query: 323 DGCVKIGDLGLARKFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFA 382
D +KI D GLAR T + +VT +YRAPE+ILG Y +DLW+VGCI
Sbjct: 162 DCTLKILDFGLAR----TAGTSFMMTPYVVTRYYRAPEVILG-MGYKENVDLWSVGCIMG 216
Query: 383 ELIGLRPIFKGEEAKMESKKSVLFQANQFQKILEVMGSP----DHKIWPNIDSY----PE 434
E++ + +F G + +Q+ K++E +G+P K+ P + +Y P+
Sbjct: 217 EMVCHKILFPGRD-----------YIDQWNKVIEQLGTPCPEFMKKLQPTVRTYVENRPK 265
Query: 435 YLQLAKMPKYRDNL-TAWYQTAGGKDKTALDILYRLLQYDPIKRIDAIDALDHVY 488
Y + + D L A + K A D+L ++L D KRI +AL H Y
Sbjct: 266 YAGYSFEKLFPDVLFPADSEHNKLKASQARDLLSKMLVIDASKRISVDEALQHPY 320
>Hs20986523 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 427
Score = 119 bits (297), Expect = 2e-26
Identities = 91/295 (30%), Positives = 149/295 (49%), Gaps = 42/295 (14%)
Query: 209 AIKKFKTEREGVEHYTGISQSACREMSLCRELDNNHLTKLVEIFLEKKS------IYMVS 262
AIKK + H ++ A RE+ L + +++ ++ L+ +F +KS +Y+V
Sbjct: 53 AIKKLSRPFQNQTH----AKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVM 108
Query: 263 EFAEHDLLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTV 322
E + +L Q+I E+ + +++Q+L G+ +LH I+HRDLKP+NI+V
Sbjct: 109 ELMDANLCQVIQMELDHER-------MSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKS 161
Query: 323 DGCVKIGDLGLARKFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFA 382
D +KI D GLAR T + +VT +YRAPE+ILG Y +DLW+VGCI
Sbjct: 162 DCTLKILDFGLAR----TAGTSFMMTPYVVTRYYRAPEVILG-MGYKENVDLWSVGCIMG 216
Query: 383 ELIGLRPIFKGEEAKMESKKSVLFQANQFQKILEVMGSP----DHKIWPNIDSY----PE 434
E++ + +F G + +Q+ K++E +G+P K+ P + +Y P+
Sbjct: 217 EMVCHKILFPGRD-----------YIDQWNKVIEQLGTPCPEFMKKLQPTVRTYVENRPK 265
Query: 435 YLQLAKMPKYRDNL-TAWYQTAGGKDKTALDILYRLLQYDPIKRIDAIDALDHVY 488
Y + + D L A + K A D+L ++L D KRI +AL H Y
Sbjct: 266 YAGYSFEKLFPDVLFPADSEHNKLKASQARDLLSKMLVIDASKRISVDEALQHPY 320
>ECU08g0230 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 265
Score = 118 bits (296), Expect = 2e-26
Identities = 64/184 (34%), Positives = 109/184 (58%), Gaps = 11/184 (5%)
Query: 211 KKFKTEREGVEHYTGISQSACREMSLCRELDNNHLTKLVEIFLEKKSIYMVSEFAEHDLL 270
+K +R + G+ +A RE+S+ ++L + ++ LV I + MV F +++L
Sbjct: 28 EKVALKRIRLNEKEGMPGTALREISILKKLSHRNIISLVSIIHTDALLTMVFPFIDYELK 87
Query: 271 QIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGCVKIGD 330
+ I ++ + + ++ Q++ GV YLH+ ++HRDLKP NI+VT DG +KI D
Sbjct: 88 KYIGMNTG--------KNIMELVNQLICGVHYLHRMNVVHRDLKPQNILVTSDGVLKIAD 139
Query: 331 LGLARKFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELIGLRPI 390
GL+R V Y+ + +VT+WYR+PEL++G+ Y +D+W++GCI E+I L P+
Sbjct: 140 FGLSRSLEIRVPP-YSSE--VVTLWYRSPELLMGSTSYRFYVDIWSLGCIIYEMITLEPL 196
Query: 391 FKGE 394
F GE
Sbjct: 197 FPGE 200
>Hs7657498 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 419
Score = 117 bits (294), Expect = 4e-26
Identities = 84/294 (28%), Positives = 145/294 (48%), Gaps = 48/294 (16%)
Query: 207 FYAIKKFKTEREGVEHYTGISQSACREMSLCRELDNN-HLTKLVEIFLEKKS--IYMVSE 263
+YA K+ K E +E + RE+ R L+ + ++ L E+ ++KS + ++ E
Sbjct: 29 YYACKQMKQRFESIEQVNNL-----REIQALRRLNPHPNILMLHEVVFDRKSGSLALICE 83
Query: 264 FAEHDLLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVD 323
+ ++ ++I +P + + + M+Q+ + ++H+N I HRD+KP NI++ D
Sbjct: 84 LMDMNIYELIRGRRYP----LSEKKIMHYMYQLCKSLDHIHRNGIFHRDVKPENILIKQD 139
Query: 324 GCVKIGDLGLARK-FNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFA 382
+K+GD G R ++ T Y I T WYRAPE +L YT +DLW+ GC+F
Sbjct: 140 -VLKLGDFGSCRSVYSKQPYTEY-----ISTRWYRAPECLLTDGFYTYKMDLWSAGCVFY 193
Query: 383 ELIGLRPIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHKIWPNID-------SYPEY 435
E+ L+P+F G + + +Q KI +V+G+P KI +P +
Sbjct: 194 EIASLQPLFPG-----------VNELDQISKIHDVIGTPAQKILTKFKQSRAMNFDFP-F 241
Query: 436 LQLAKMPKYRDNLTAWYQTAGGKDKTALDILYRLLQYDPIKRIDAIDALDHVYF 489
+ + +P NL+ L +L+ ++ YDP +RI A AL H YF
Sbjct: 242 KKGSGIPLLTTNLS----------PQCLSLLHAMVAYDPDERIAAHQALQHPYF 285
>At1g09600 [D] KOG0600 Cdc2-related protein kinase
Length = 714
Score = 117 bits (294), Expect = 4e-26
Identities = 80/261 (30%), Positives = 127/261 (48%), Gaps = 23/261 (8%)
Query: 232 REMSLCRELDNNHLTKLVEIFLEKKS--IYMVSEFAEHDLLQIIHFHSHPEKRLIPPRML 289
RE+ + R LD+ ++ KL + + S +Y++ E+ EHDL + S P + +
Sbjct: 209 REIIILRRLDHPNVMKLEGLITSRVSGSMYLIFEYMEHDLAGLA---STPGINFSEAQ-I 264
Query: 290 KSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGCVKIGDLGLARKFNNMVQTLYTGDK 349
K M Q+L G+ + H +LHRD+K +N+++ + +KIGD GLA + + T
Sbjct: 265 KCYMKQLLHGLEHCHSRGVLHRDIKGSNLLLDHNNNLKIGDFGLANFYQGHQKQPLTSR- 323
Query: 350 VIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELIGLRPIFKGEEAKMESKKSVLFQAN 409
+VT+WYR PEL+LG+ Y +DLW+ GCI AEL +PI G +
Sbjct: 324 -VVTLWYRPPELLLGSTDYGVTVDLWSTGCILAELFTGKPIMPGRT-----------EVE 371
Query: 410 QFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPKYRDNLTAWYQTAGGKDKTALDILYRL 469
Q KI ++ GSP + W I P Y+ + +T +AL ++ L
Sbjct: 372 QLHKIFKLCGSPSEEYW-KISKLPHATIFKPQQPYKRCVA---ETFKSLPSSALALVEVL 427
Query: 470 LQYDPIKRIDAIDALDHVYFT 490
L +P R AL+ +FT
Sbjct: 428 LAVEPDARGTTASALESEFFT 448
>Hs20986521 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 427
Score = 117 bits (293), Expect = 5e-26
Identities = 91/295 (30%), Positives = 148/295 (49%), Gaps = 42/295 (14%)
Query: 209 AIKKFKTEREGVEHYTGISQSACREMSLCRELDNNHLTKLVEIFLEKKS------IYMVS 262
AIKK + H ++ A RE+ L + +++ ++ L+ +F +KS +Y+V
Sbjct: 53 AIKKLSRPFQNQTH----AKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVM 108
Query: 263 EFAEHDLLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTV 322
E + +L Q+I E+ + +++Q+L G+ +LH I+HRDLKP+NI+V
Sbjct: 109 ELMDANLCQVIQMELDHER-------MSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKS 161
Query: 323 DGCVKIGDLGLARKFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFA 382
D +KI D GLAR T + +VT +YRAPE+ILG Y +D+W+VGCI
Sbjct: 162 DCTLKILDFGLAR----TAGTSFMMTPYVVTRYYRAPEVILG-MGYKENVDIWSVGCIMG 216
Query: 383 ELIGLRPIFKGEEAKMESKKSVLFQANQFQKILEVMGSP----DHKIWPNIDSY----PE 434
E+I +F G + +Q+ K++E +G+P K+ P + +Y P+
Sbjct: 217 EMIKGGVLFPGTD-----------HIDQWNKVIEQLGTPCPEFMKKLQPTVRTYVENRPK 265
Query: 435 YLQLAKMPKYRDNL-TAWYQTAGGKDKTALDILYRLLQYDPIKRIDAIDALDHVY 488
Y + + D L A + K A D+L ++L D KRI +AL H Y
Sbjct: 266 YAGYSFEKLFPDVLFPADSEHNKLKASQARDLLSKMLVIDASKRISVDEALQHPY 320
>Hs20986519 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 384
Score = 117 bits (293), Expect = 5e-26
Identities = 91/295 (30%), Positives = 148/295 (49%), Gaps = 42/295 (14%)
Query: 209 AIKKFKTEREGVEHYTGISQSACREMSLCRELDNNHLTKLVEIFLEKKS------IYMVS 262
AIKK + H ++ A RE+ L + +++ ++ L+ +F +KS +Y+V
Sbjct: 53 AIKKLSRPFQNQTH----AKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVM 108
Query: 263 EFAEHDLLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTV 322
E + +L Q+I E+ + +++Q+L G+ +LH I+HRDLKP+NI+V
Sbjct: 109 ELMDANLCQVIQMELDHER-------MSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKS 161
Query: 323 DGCVKIGDLGLARKFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFA 382
D +KI D GLAR T + +VT +YRAPE+ILG Y +D+W+VGCI
Sbjct: 162 DCTLKILDFGLAR----TAGTSFMMTPYVVTRYYRAPEVILG-MGYKENVDIWSVGCIMG 216
Query: 383 ELIGLRPIFKGEEAKMESKKSVLFQANQFQKILEVMGSP----DHKIWPNIDSY----PE 434
E+I +F G + +Q+ K++E +G+P K+ P + +Y P+
Sbjct: 217 EMIKGGVLFPGTD-----------HIDQWNKVIEQLGTPCPEFMKKLQPTVRTYVENRPK 265
Query: 435 YLQLAKMPKYRDNL-TAWYQTAGGKDKTALDILYRLLQYDPIKRIDAIDALDHVY 488
Y + + D L A + K A D+L ++L D KRI +AL H Y
Sbjct: 266 YAGYSFEKLFPDVLFPADSEHNKLKASQARDLLSKMLVIDASKRISVDEALQHPY 320
>At2g42880 [T] KOG0660 Mitogen-activated protein kinase
Length = 594
Score = 117 bits (293), Expect = 5e-26
Identities = 92/298 (30%), Positives = 146/298 (48%), Gaps = 33/298 (11%)
Query: 232 REMSLCRELDNNHLTKLVEIFL-----EKKSIYMVSEFAEHDLLQIIHFHSHPEKRLIPP 286
RE+ L R L + + ++ I L E K IY+V E E DL Q+I + +
Sbjct: 59 REIKLLRLLRHPDIVEIKHIMLPPSRREFKDIYVVFELMESDLHQVIKANDD-----LTR 113
Query: 287 RMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGCVKIGDLGLAR-KFNNMVQTLY 345
+ ++Q+L + Y+H + HRDLKP NI+ + +KI D GLAR FN+ T++
Sbjct: 114 EHYQFFLYQLLRALKYIHTANVYHRDLKPKNILANANCKLKICDFGLARVAFNDTPTTIF 173
Query: 346 TGDKVIVTIWYRAPELILGARH--YTPAIDLWAVGCIFAELIGLRPIFKGEEAKMESKKS 403
D V T WYRAPEL G+ + YTPAID+W++GCIFAE++ +P+F G+
Sbjct: 174 WTDYV-ATRWYRAPEL-CGSFYSKYTPAIDIWSIGCIFAEVLMGKPLFPGKNV------- 224
Query: 404 VLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPKYRDNLTAWYQTAGGKDKTAL 463
+Q + +++G+P + + L M K + Q D +L
Sbjct: 225 ----VHQLDLMTDLLGTPSLDTISRVRNEKARRYLTSMRKKPP--IPFAQKFPNADPLSL 278
Query: 464 DILYRLLQYDPIKRIDAIDALDHVYFTN----GDPPVCENVFEGLNYKYPPRRIHTND 517
+L RLL +DP R A +AL YF P C+ + + + +++ R++ D
Sbjct: 279 KLLERLLAFDPKDRPTAEEALADPYFKGLAKVEREPSCQPITK-MEFEFERRKVTKED 335
>CE11556 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 305
Score = 115 bits (289), Expect = 1e-25
Identities = 84/271 (30%), Positives = 120/271 (43%), Gaps = 36/271 (13%)
Query: 229 SACREMSLCRELDNNHLTKLVEIFLEKKSIYMVSEFAEHDLLQIIHFHSHPEKRLIPPRM 288
S RE+S R L + ++ KL++ F + +V+E +
Sbjct: 48 SLAREISCLRNLHHRNILKLLDCFPSADLMSIVTEEVPYTWYYT---------------- 91
Query: 289 LKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGCVKIGDLGLARKFNNMVQTLYTGD 348
QIL G++YLH I+HRD+KP NI+VT VKI D G A F D
Sbjct: 92 ------QILSGIAYLHSKEIMHRDIKPENILVTSRNVVKIADFGQAC-FYMPKDPNQEYD 144
Query: 349 KVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELIGLRPIFKGEEAKMESKKSVLFQA 408
+ T WYRAPEL+ G++ Y P +D+WA+GCI AEL+ +PIF G +
Sbjct: 145 VNVATRWYRAPELLFGSKKYKPDVDIWAIGCILAELVRGKPIFPGRS-----------EL 193
Query: 409 NQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPKYRDNLTAWYQTAGGKDKTALDILYR 468
Q I V+G+P+ WPN + P+ +L PK N + L
Sbjct: 194 EQISIIFGVLGTPNEDNWPNWRTMPDANKLLFEPKEPRNNWTEILLCKEISNNFTEFLGS 253
Query: 469 LLQYDPIKRIDAIDALDHVYFTNGDPPVCEN 499
LQ+ KR+ A + L + G P V N
Sbjct: 254 HLQF--FKRLKASELLKEPWIKQGLPLVEPN 282
>SPBPI064 [G] KOG0658 Glycogen synthase kinase-3
Length = 350
Score = 115 bits (288), Expect = 2e-25
Identities = 78/274 (28%), Positives = 135/274 (48%), Gaps = 29/274 (10%)
Query: 232 REMSLCRELDNNHLTKLVEIF------LEKKSIYMVSEFAEHDLLQIIHFHSHPEKRLIP 285
RE+ + R + + ++ KL+ F ++ + ++ E+ + + +++ K IP
Sbjct: 34 RELQIMRAISHPNIIKLIAFFHTHNPSKDETHLCLLLEYMPETVFDDMRWYTRRRKS-IP 92
Query: 286 PRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVD-GCVKIGDLGLARKFNNMVQTL 344
+K +Q+ ++YLH + HRD+KP N++V G +K+ D G A+ ++
Sbjct: 93 NLSIKLYAFQLFRALAYLHSTGVCHRDIKPQNLLVDYKTGILKLCDFGSAK----VLVPS 148
Query: 345 YTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELIGLRPIFKGEEAKMESKKSV 404
I + +YRAPEL+ GA HYT ID+W+ C+ AEL RP+F G+ +
Sbjct: 149 EPNVSYICSRYYRAPELVFGATHYTTKIDVWSAACVIAELFIGRPLFPGDSS-------- 200
Query: 405 LFQANQFQKILEVMGSPD-HKIWPNIDSYPEYLQLAKMPKYRDNLTAWYQTAGGKDKTAL 463
Q +I+ V+G+P H+I +Y + +P R + T K A+
Sbjct: 201 ---VEQLVEIIRVLGTPSYHEISVMNPNYVNH----SLPNVRPH-TLESVMPHNCTKNAM 252
Query: 464 DILYRLLQYDPIKRIDAIDALDHVYFTNGDPPVC 497
D+L+++L Y P KRI AI+ L H +F P C
Sbjct: 253 DLLHKMLTYVPSKRISAIEVLTHPFFDELRDPNC 286
>SPBC8D2.01 [G] KOG0658 Glycogen synthase kinase-3
Length = 381
Score = 115 bits (288), Expect = 2e-25
Identities = 78/274 (28%), Positives = 135/274 (48%), Gaps = 29/274 (10%)
Query: 232 REMSLCRELDNNHLTKLVEIF------LEKKSIYMVSEFAEHDLLQIIHFHSHPEKRLIP 285
RE+ + R + + ++ KL+ F ++ + ++ E+ + + +++ K IP
Sbjct: 65 RELQIMRAISHPNIIKLIAFFHTHNPSKDETHLCLLLEYMPETVFDDMRWYTRRRKS-IP 123
Query: 286 PRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVD-GCVKIGDLGLARKFNNMVQTL 344
+K +Q+ ++YLH + HRD+KP N++V G +K+ D G A+ ++
Sbjct: 124 NLSIKLYAFQLFRALAYLHSTGVCHRDIKPQNLLVDYKTGILKLCDFGSAK----VLVPS 179
Query: 345 YTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELIGLRPIFKGEEAKMESKKSV 404
I + +YRAPEL+ GA HYT ID+W+ C+ AEL RP+F G+ +
Sbjct: 180 EPNVSYICSRYYRAPELVFGATHYTTKIDVWSAACVIAELFIGRPLFPGDSS-------- 231
Query: 405 LFQANQFQKILEVMGSPD-HKIWPNIDSYPEYLQLAKMPKYRDNLTAWYQTAGGKDKTAL 463
Q +I+ V+G+P H+I +Y + +P R + T K A+
Sbjct: 232 ---VEQLVEIIRVLGTPSYHEISVMNPNYVNH----SLPNVRPH-TLESVMPHNCTKNAM 283
Query: 464 DILYRLLQYDPIKRIDAIDALDHVYFTNGDPPVC 497
D+L+++L Y P KRI AI+ L H +F P C
Sbjct: 284 DLLHKMLTYVPSKRISAIEVLTHPFFDELRDPNC 317
>Hs17452757 [UT] KOG0662 Cyclin-dependent kinase CDK5
Length = 366
Score = 115 bits (288), Expect = 2e-25
Identities = 78/272 (28%), Positives = 135/272 (48%), Gaps = 37/272 (13%)
Query: 225 GISQSACREMSLCRELDNNHLTKLVEIFLEKKSIYMVSEFAEHDLLQIIHFHSHPEKRLI 284
G+ SA RE+ L +EL + ++ +L ++ K + +V +F L + +F S +
Sbjct: 114 GVPSSALREICLLKELKHKNIVRLHDLLHSDKKLTLVFKFCHQHLKK--YFDSCNGD--L 169
Query: 285 PPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGCVKIGDLGLARKFNNMVQTL 344
P ++KS ++Q+L G+ + H +L RDLKP N+++ +G +K+ D GL+R F
Sbjct: 170 DPEIVKSFLFQLLKGLGFCHSRNVLRRDLKPQNLLINRNGELKLADFGLSRAFG------ 223
Query: 345 YTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELIGLR-PIFKGEEAKMESKKS 403
+ I Y + GA+ Y+ +IDLW+ GCIFAEL P+F G +
Sbjct: 224 -------IPICY----VFFGAKLYSTSIDLWSAGCIFAELANAGWPLFPGNDVD------ 266
Query: 404 VLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPKYRDNLTAWYQTAGGKDKTAL 463
+Q ++I ++G + WP++ P+Y K+ T+ T
Sbjct: 267 -----DQLKRIFWLLGMLTKEQWPSMTKLPDY----KLYPLYPATTSLVNIVPKLSATGR 317
Query: 464 DILYRLLQYDPIKRIDAIDALDHVYFTNGDPP 495
D+L LL+ +P + I A +AL + YF++ PP
Sbjct: 318 DLLQNLLKCNPCQCISAEEALQYPYFSDFCPP 349
>CE29466 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 390
Score = 115 bits (288), Expect = 2e-25
Identities = 88/289 (30%), Positives = 142/289 (48%), Gaps = 57/289 (19%)
Query: 227 SQSACREMSLCRELDNNHLTKLVEIFLEKKS------IYMVSEFAEHDLLQIIHFHSHPE 280
++ A RE L + + ++ +L+ F S +Y+V E H+L ++IH
Sbjct: 79 AKRAYREFILLTTIKHPNIIRLLNAFTPDTSLSTFREVYLVMELMTHNLHEVIH------ 132
Query: 281 KRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGCV-KIGDLGLARKFNN 339
+ + + L ++Q L + +LH + ++HRDLKP+NI+V D CV K+ D GLARK N
Sbjct: 133 RLRLDHKTLSFFVYQSLCAIKHLHNSGVIHRDLKPSNIVVN-DRCVLKVLDFGLARKKN- 190
Query: 340 MVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELIGLRPIFKGEEAKME 399
V T +VT +YRAPE+ILG Y+ +D+W+VGCIFAE+I +F G++
Sbjct: 191 -VDTSMRMSDYVVTRYYRAPEVILGLP-YSEKVDIWSVGCIFAEMINHTVLFPGKD---- 244
Query: 400 SKKSVLFQANQFQKILEVMGSPD--------------------HKIWPNIDSYPEYLQLA 439
+ +Q+ KI V+G+PD H+ + P+ L
Sbjct: 245 -------RIDQWTKIYSVLGTPDDHFISQLGQSAAMYVRSLPRHQARAFSEIVPDTNFLP 297
Query: 440 KMPKYRDNLTAWYQTAGGKDKTALDILYRLLQYDPIKRIDAIDALDHVY 488
+ R +LT A D+L+ +L+ +P +R DAL+H Y
Sbjct: 298 ETENPRVHLTP---------HVARDLLFNMLKINPEERYSVEDALNHPY 337
>CE06762 [T] KOG0660 Mitogen-activated protein kinase
Length = 367
Score = 114 bits (285), Expect = 4e-25
Identities = 77/279 (27%), Positives = 141/279 (49%), Gaps = 40/279 (14%)
Query: 226 ISQSACREMSLCRELDNNHLTKLVEIFLEK----KSIYMVSEFAEHDLLQIIHFHSHPEK 281
+++ + RE+ + REL + ++ ++++F + K IY+V + E DL QI+H +
Sbjct: 97 LAKRSLREVRILRELLHENIIAVLDMFTAEGAHGKDIYLVMDLMETDLHQILH-----SR 151
Query: 282 RLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGCVKIGDLGLARKFNNMV 341
+ + + + +Q+L G+ YLH I+HRDLKP+N+++ D ++I D G+AR + +
Sbjct: 152 QTLMEQHFQYFFYQLLRGLKYLHSAGIIHRDLKPSNLLLNGDCLLRIADFGMARAYASAS 211
Query: 342 QTLYTGD------KVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELIGLRPIFKGEE 395
+ + + T WYRAPE++ Y +DLW+ GCIFAE++ R +F G++
Sbjct: 212 TVRDDANVGGHMTQYVSTRWYRAPEILFSMVEYDTKVDLWSAGCIFAEMLLRRQLFPGKD 271
Query: 396 AKMESKKSVLFQANQFQKILEVMGSPDHKIWPNI------DSYPEYLQLAKMPKYRDNLT 449
+ +Q + I+ +GSP+ ++ I DS + +P +
Sbjct: 272 S-----------VSQIKMIVYYLGSPEEEVINRITSDLVRDSIEACGRKTPLP-----FS 315
Query: 450 AWYQTAGGKDKTALDILYRLLQYDPIKRIDAIDALDHVY 488
A + A + A +++ LLQ P KR A L H +
Sbjct: 316 AIFPKASPE---ARNMVSYLLQISPWKRYSADQILQHPF 351
>Hs7106269 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 452
Score = 114 bits (284), Expect = 5e-25
Identities = 78/272 (28%), Positives = 126/272 (45%), Gaps = 42/272 (15%)
Query: 225 GISQSACREMSLCREL-DNNHLTKLVEIFLEKKSIYMVSEFAEHDLLQIIHFHSHPEKRL 283
G A RE+ +E+ DN ++ +L +F + EF DL +++ P
Sbjct: 43 GFPNQALREIKALQEMEDNQYVVQLKAVFPHGGGFVLAFEFMLSDLAEVVRHAQRP---- 98
Query: 284 IPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGCVKIGDLGLARKFNNMVQT 343
+ +KS + +L GV++ H N I+HRDLKPAN++++ G +KI D GLAR F
Sbjct: 99 LAQAQVKSYLQMLLKGVAFCHANNIVHRDLKPANLLISASGQLKIADFGLARVF------ 152
Query: 344 LYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELIGLRPIFKGEEAKMESKKS 403
+P+ G+R YT + +VGCI EL+ P+F G+
Sbjct: 153 --------------SPD---GSRLYTHQVATRSVGCIMGELLNGSPLFPGKN-------- 187
Query: 404 VLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPKYRDNLTAWYQTAGGKDKTAL 463
Q +L ++G+P+ ++WP + P+Y +++ + L + AL
Sbjct: 188 ---DIEQLCYVLRILGTPNPQVWPELTELPDYNKISFKEQVPMPLE---EVLPDVSPQAL 241
Query: 464 DILYRLLQYDPIKRIDAIDALDHVYFTNGDPP 495
D+L + L Y P +RI A AL H YF P
Sbjct: 242 DLLGQFLLYPPHQRIAASKALLHQYFFTAPLP 273
>YJL106w [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 645
Score = 112 bits (280), Expect = 2e-24
Identities = 85/319 (26%), Positives = 153/319 (47%), Gaps = 61/319 (19%)
Query: 209 AIKKFKTEREGVEHYTGISQSACREMSLCRELD-NNHLTKLVEIFLEKKS--IYMVSEFA 265
AIK T+ ++ YT + RE+ + N+HL ++ E+F++ ++ +++V E
Sbjct: 95 AIKTMMTKLHTLQDYTRV-----REIKFILAIPANDHLIQIFEVFIDSENYQLHIVMECM 149
Query: 266 EHDLLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDG- 324
E +L Q++ H +R+ LKSI+ QIL G+ ++H++ HRDLKP NI++T
Sbjct: 150 EQNLYQMM---KHRRRRVFSIPSLKSILSQILAGLKHIHEHNFFHRDLKPENILITPSTQ 206
Query: 325 ----------------CVKIGDLGLARKFNNMVQTLYTGDKVIVTIWYRAPELILGARHY 368
+K+ D GLAR N + YT + T WYR+PE++L + +Y
Sbjct: 207 YFEKEYMNQIGYQDNYVIKLADFGLARHVEN--KNPYTA--YVSTRWYRSPEILLRSGYY 262
Query: 369 TPAIDLWAVGCIFAELIGLRPIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHK---- 424
+ +D+WA GC+ E+ R +F G + +Q KILEV+G+P +
Sbjct: 263 SKPLDIWAFGCVAVEVTVFRALFPGAN-----------EIDQIWKILEVLGTPIKRSDFV 311
Query: 425 ------------IWPNIDSYPEYLQLAKMPKYRDNLTAWYQTAGGKDKTALDILYRLLQY 472
W + + L L K+P Y + + + + + +++ + L++
Sbjct: 312 NTNHITAPPPGGFWDDASNLVHKLNL-KLP-YVEGSSLDHLLSSSQLSDLSEVVKKCLRW 369
Query: 473 DPIKRIDAIDALDHVYFTN 491
DP +R A + + +F N
Sbjct: 370 DPNERATAQELCEMPFFEN 388
>ECU11g1290 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 328
Score = 112 bits (280), Expect = 2e-24
Identities = 72/262 (27%), Positives = 128/262 (48%), Gaps = 28/262 (10%)
Query: 225 GISQSACREMSLCRELDNNHLTKLVEIF--LEKKSIYMVSEFAEHDLLQIIHFHSHPEKR 282
G S RE+ + + + + ++ ++ E+ E ++V E + DL +IH
Sbjct: 67 GFSILYIREVMILKHIRHRNIMEIEEVVEGCEINDFFIVMECCDTDLRSVIHSVGK---- 122
Query: 283 LIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGCVKIGDLGLARKFNNMVQ 342
I + + + Q+L G+ +LH I+HRDLKP+NI++ DG ++I D GLAR + +
Sbjct: 123 -IGMKAARFLTCQMLKGLKFLHGAGIVHRDLKPSNILLMRDGGLRIADFGLARAIESQMT 181
Query: 343 TLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELIGLRPIFKGEEAKMESKK 402
L +VT+WYR E++LG+ Y +ID+W+VGC+ E++ PI GE
Sbjct: 182 NL------VVTLWYRPIEILLGSETYDESIDMWSVGCVVGEMLRGEPILAGEG------- 228
Query: 403 SVLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPKYRDNLTAWYQTAGGKDKTA 462
+ +Q +I ++G P + +D P + + + + + ++ G + A
Sbjct: 229 ----EMDQLDRIFRLLGYPTDADFEGLD-LPHFKNIRRPSTFEASFEGDFECYG---EEA 280
Query: 463 LDILYRLLQYDPIKRIDAIDAL 484
+ LL +DP KR A L
Sbjct: 281 ASFVRNLLSFDPRKRCTASQGL 302
>CE17062 [T] KOG0660 Mitogen-activated protein kinase
Length = 448
Score = 112 bits (280), Expect = 2e-24
Identities = 96/346 (27%), Positives = 152/346 (43%), Gaps = 85/346 (24%)
Query: 209 AIKKFKTEREGVEHYTGISQSACREMSLCRELDNNHLTKLVEIFLEK------KSIYMVS 262
AIKKF + H ++ RE+ L R L ++++ +++++F ++Y VS
Sbjct: 76 AIKKFFRPFQSTIH----AKRTYRELKLLRTLQHDNVLEMIDVFTPDPDASSLNNVYFVS 131
Query: 263 EFAEHDLLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYL-HQNW-------------- 307
DL I+ ++++ + +++Q+L G+ Y+ HQN+
Sbjct: 132 VLMGSDLQNIMKIQRLTDEQI------QLLIYQVLRGLKYMSHQNFNSTIILKKLMHPFQ 185
Query: 308 --------------ILHRDLKPANIMVT-----------------VDGCVKIGDLGLARK 336
I+HRDLKP+NI V + KI D GLAR
Sbjct: 186 RRNTRFRLYIHSAGIIHRDLKPSNIAVNERCEVKVFLSFSQLSFLILSFFKILDFGLARA 245
Query: 337 FNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELIGLRPIFKGEEA 396
+ T Y + T WYRAPE++L HYT +D+W+VGCI AEL+ RP+F G++
Sbjct: 246 -QDAEMTGY-----VATRWYRAPEIMLNWMHYTQTVDVWSVGCILAELVSGRPLFPGDD- 298
Query: 397 KMESKKSVLFQANQFQKILEVMGSPDHKIWPNIDSYP--EYLQLAKMPKYRDNLTAWYQT 454
+Q KI+ V+G+P + W I S Y++ + P R + +
Sbjct: 299 ----------HIDQLTKIMSVVGTPKEEFWSKIQSEEARNYIK-NRSPIIRQDFVTLFPM 347
Query: 455 AGGKDKTALDILYRLLQYDPIKRIDAIDALDHVYFTNGDPPVCENV 500
A AL++L +L DP +RI AL H Y P E V
Sbjct: 348 A---SPYALELLEMMLILDPDRRISVSSALRHDYLREYSVPNDEPV 390
>7300773 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 302
Score = 112 bits (280), Expect = 2e-24
Identities = 74/277 (26%), Positives = 136/277 (48%), Gaps = 32/277 (11%)
Query: 209 AIKKFKTEREGVEHYTGISQSACREMSLCRELDNNHLTKLVEIFLEKKSIYMVSEFAEHD 268
AIKK + + + I+ + RE+ + + ++ +++I+ + + +V E+
Sbjct: 36 AIKKVALKNK----FGNIALNTLREIKTLQLCKSEYILDIIDIYPDLTGLSLVLEYQPDT 91
Query: 269 LLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGCVKI 328
L + +P R + ++ Q+ G++YLH+ ++HRD+KPAN++++ +KI
Sbjct: 92 LYNRLKSEVNPLSR----QQVRKFAHQMFKGIAYLHEAGLMHRDIKPANLLISDTDMLKI 147
Query: 329 GDLGLARK-FNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELIGL 387
D GLAR F LY+ + T WYRAPE++ G++ Y +D+WA GC+ AE++
Sbjct: 148 ADFGLARLYFPEDESRLYSPQ--VSTRWYRAPEILFGSQKYGTGVDMWAAGCVVAEMLRG 205
Query: 388 RPIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPK---- 443
P+F G Q I+ +GSP WP + S P+Y ++ + P
Sbjct: 206 VPLFAGTT-----------DIEQLAIIIRTLGSPRLNQWPELTSLPDYSKI-RFPNSVGI 253
Query: 444 YRDNLTAWYQTAGGKDKTALDILYRLLQYDPIKRIDA 480
+ DNL A ++++ L+ Y+P R+ A
Sbjct: 254 HWDNLFPSCTHA-----VEINLVSNLVVYNPKNRLKA 285
>At4g18710 [G] KOG0658 Glycogen synthase kinase-3
Length = 380
Score = 112 bits (279), Expect = 2e-24
Identities = 82/266 (30%), Positives = 137/266 (50%), Gaps = 29/266 (10%)
Query: 232 REMSLCRELDNNHLTKLVEIFLEKKS-----IYMVSEFAEHDLLQIIHFHSHPEKRLIPP 286
RE+ L R +D+ ++ L F S + +V E+ L +++ +S +R+ P
Sbjct: 80 RELQLMRVMDHPNVVCLKHCFFSTTSKDELFLNLVMEYVPESLYRVLKHYSSANQRM-PL 138
Query: 287 RMLKSIMWQILDGVSYLHQ-NWILHRDLKPANIMVT-VDGCVKIGDLGLARKFNNMVQTL 344
+K M+QI G++Y+H + HRDLKP N++V + VKI D G A++ +
Sbjct: 139 VYVKLYMYQIFRGLAYIHNVAGVCHRDLKPQNLLVDPLTHQVKICDFGSAKQLVKGEANI 198
Query: 345 YTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELIGLRPIFKGEEAKMESKKSV 404
I + +YRAPELI GA YT +ID+W+ GC+ AEL+ +P+F GE A
Sbjct: 199 ----SYICSRFYRAPELIFGATEYTTSIDIWSAGCVLAELLLGQPLFPGENA-------- 246
Query: 405 LFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPKYRDNLTAWYQTAGGK-DKTAL 463
+Q +I++V+G+P + ++ P Y + P+ + + W++ + A+
Sbjct: 247 ---VDQLVEIIKVLGTPTREEIRCMN--PHYTDF-RFPQIKAH--PWHKIFHKRMPPEAI 298
Query: 464 DILYRLLQYDPIKRIDAIDALDHVYF 489
D RLLQY P R A++A H +F
Sbjct: 299 DFASRLLQYSPSLRCTALEACAHPFF 324
>Hs21361340 [G] KOG0658 Glycogen synthase kinase-3
Length = 433
Score = 111 bits (278), Expect = 3e-24
Identities = 79/278 (28%), Positives = 144/278 (51%), Gaps = 40/278 (14%)
Query: 232 REMSLCRELDNNHLTKLVEIFL----EKKSIYM--VSEFAEHDLLQIIHFHSHPEKRLIP 285
RE+ + R+LD+ ++ +L F +K +Y+ V ++ + ++ +S K+ +P
Sbjct: 96 RELQIMRKLDHCNIVRLRYFFYSSGEKKDEVYLNLVLDYVPETVYRVARHYSRA-KQTLP 154
Query: 286 PRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGCV-KIGDLGLARKFNNMVQTL 344
+K M+Q+ ++Y+H I HRD+KP N+++ D V K+ D G A++ L
Sbjct: 155 VIYVKLYMYQLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQ-------L 207
Query: 345 YTGD---KVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELIGLRPIFKGEEAKMESK 401
G+ I + +YRAPELI GA YT +ID+W+ GC+ AEL+ +PIF G+
Sbjct: 208 VRGEPNVSYICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSG----- 262
Query: 402 KSVLFQANQFQKILEVMGSPD----HKIWPNIDSYPEYLQLAKMPKYRDNLTAWYQTAGG 457
+Q +I++V+G+P ++ PN + ++ Q+ P +D+ + T+G
Sbjct: 263 ------VDQLVEIIKVLGTPTREQIREMNPNYTEF-KFPQIKAHPWTKDSSGTGHFTSGV 315
Query: 458 K------DKTALDILYRLLQYDPIKRIDAIDALDHVYF 489
+ A+ + RLL+Y P R+ ++A H +F
Sbjct: 316 RVFRPRTPPEAIALCSRLLEYTPTARLTPLEACAHSFF 353
>CE17305 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 375
Score = 111 bits (278), Expect = 3e-24
Identities = 85/281 (30%), Positives = 142/281 (50%), Gaps = 43/281 (15%)
Query: 227 SQSACREMSLCRELDNNHLTKLVEIFLEKKS------IYMVSEFAEHDLLQIIHFHSHPE 280
++ A RE L L + ++ +L+ F S +Y+V EF H+L ++IH
Sbjct: 70 ARRAYREFILLTTLKHPNIIRLLNAFTPDTSLSSFQEVYLVMEFMTHNLHEVIH------ 123
Query: 281 KRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGCVKIGDLGLARKFN-N 339
+ + L +++Q L + +LH +HRDLKP+NI+V +K+ D GLAR+ N +
Sbjct: 124 RLRLDHETLSFLVYQSLCAIKHLHNLGFIHRDLKPSNIVVNERCVLKVLDFGLARRRNVD 183
Query: 340 MVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELIGLRPIFKGEEAKME 399
M + Y G T +YRAPE+ILG +Y+ +D+W+VGCI AE+I +F G++ +
Sbjct: 184 MRMSDYVG-----TRYYRAPEVILGL-NYSEKVDIWSVGCILAEMINHTVLFPGKDIR-- 235
Query: 400 SKKSVLFQANQFQKILEVMGSPDHKIWPNID--------SYPEYLQLAKMPKYRDNLTAW 451
+Q+ +I V+ +PD ++ S P++L A D+
Sbjct: 236 ---------DQWTQISSVLRTPDDHFINQLEPIGAVYVRSLPQHLARAFNEIVPDS-NFL 285
Query: 452 YQTAGGKDKTAL----DILYRLLQYDPIKRIDAIDALDHVY 488
+T KD L D+L+ +L+ +P +R DAL+H Y
Sbjct: 286 PETENPKDHLTLHMARDLLFNMLKINPEERYSVEDALNHPY 326
>Hs20986514 [T] KOG0660 Mitogen-activated protein kinase
Length = 297
Score = 111 bits (277), Expect = 4e-24
Identities = 75/244 (30%), Positives = 128/244 (51%), Gaps = 36/244 (14%)
Query: 209 AIKKFKTEREGVEHYTGISQSACREMSLCRELDNNHLTKLVEIFLEKKS------IYMVS 262
A+KK + + H ++ RE+ L + + + ++ L+++F +S +Y+V+
Sbjct: 51 AVKKLSRPFQSIIH----AKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVT 106
Query: 263 EFAEHDLLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTV 322
DL I+ + + + +++QIL G+ Y+H I+HRDLKP+N+ V
Sbjct: 107 HLMGADLNNIVKCQKLTDDHV------QFLIYQILRGLKYIHSADIIHRDLKPSNLAVNE 160
Query: 323 DGCVKIGDLGLARKFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFA 382
D +KI D GLAR ++ + TG + T WYRAPE++L HY +D+W+VGCI A
Sbjct: 161 DCELKILDFGLARHTDDEM----TG--YVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMA 214
Query: 383 ELIGLRPIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHKIWPNI--DSYPEYLQ-LA 439
EL+ R +F G + +Q + IL ++G+P ++ I +S Y+Q L
Sbjct: 215 ELLTGRTLFPGTD-----------HIDQLKLILRLVGTPGAELLKKISSESARNYIQSLT 263
Query: 440 KMPK 443
+MPK
Sbjct: 264 QMPK 267
>Hs20986508 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 277
Score = 110 bits (276), Expect = 5e-24
Identities = 78/235 (33%), Positives = 121/235 (51%), Gaps = 32/235 (13%)
Query: 263 EFAEHDLLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTV 322
E + +L Q+I E+ + +++Q+L G+ +LH I+HRDLKP+NI+V
Sbjct: 2 ELMDANLCQVIQMELDHER-------MSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKS 54
Query: 323 DGCVKIGDLGLARKFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFA 382
D +KI D GLAR T + +VT +YRAPE+ILG Y +D+W+VGCI
Sbjct: 55 DCTLKILDFGLAR----TAGTSFMMTPYVVTRYYRAPEVILG-MGYKENVDIWSVGCIMG 109
Query: 383 ELIGLRPIFKGEEAKMESKKSVLFQANQFQKILEVMGSP----DHKIWPNIDSY----PE 434
E++ + +F G + +Q+ K++E +G+P K+ P + +Y P+
Sbjct: 110 EMVRHKILFPGRD-----------YIDQWNKVIEQLGTPCPEFMKKLQPTVRNYVENRPK 158
Query: 435 YLQLAKMPKYRDNL-TAWYQTAGGKDKTALDILYRLLQYDPIKRIDAIDALDHVY 488
Y L + D+L A + K A D+L ++L DP KRI DAL H Y
Sbjct: 159 YAGLTFPKLFPDSLFPADSEHNKLKASQARDLLSKMLVIDPAKRISVDDALQHPY 213
>CE27220 [T] KOG0660 Mitogen-activated protein kinase
Length = 472
Score = 109 bits (273), Expect = 1e-23
Identities = 76/281 (27%), Positives = 139/281 (49%), Gaps = 33/281 (11%)
Query: 226 ISQSACREMSLCRELDNNHLTKLVEIFLEKK----SIYMVSEFAEHDLLQIIHFHSHPEK 281
+++ RE+ + R +++ ++ L +IF K +++V + +++L II+ + P
Sbjct: 122 LARRTLREIRVLRYINHPNIVPLRDIFRTKGPLGIDVFLVMDLMQNNLHHIIYGNEDP-- 179
Query: 282 RLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGCVKIGDLGLAR------ 335
+ + + + Q+L G+ YLH I HRDLKP+N++V DG ++I D G+A+
Sbjct: 180 --LEEHYINAFLGQLLRGLEYLHAACIAHRDLKPSNLLVNQDGTLRIADFGMAKCADNSS 237
Query: 336 KFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELIGLRPIFKGEE 395
K ++ + Y + + T+ YRAPEL+ ++ A+D+WAVGCIF E++ I G
Sbjct: 238 KKHDDEEHCYYMTQHVATLPYRAPELLFVLPEHSTAVDMWAVGCIFGEMVIRNEILPGRS 297
Query: 396 AKMESKKSVLFQANQFQKILEVMGSPDHKIWPNI--DSYPEYLQLAKMPKYRDNLTAWYQ 453
+ Q + +L ++G P ++ + D + +Q + +
Sbjct: 298 VQ-----------GQIKMLLTMLGQPPQEVINEVRCDRTRKLIQDFGRKADAEWDDIMFC 346
Query: 454 TAGGKDK------TALDILYRLLQYDPIKRIDAIDALDHVY 488
A G D+ +D + +L QYD KRI+ DAL H Y
Sbjct: 347 KARGDDQIVRGNCDTIDFVKQLFQYDAQKRINIQDALLHPY 387
>SPAC3C7.06c [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 650
Score = 109 bits (272), Expect = 1e-23
Identities = 88/299 (29%), Positives = 151/299 (50%), Gaps = 52/299 (17%)
Query: 209 AIKKFKTEREGVEHYTGISQSACREM-SLCRELDNNHLTKLVEIFLEK-KSIYMVSEFAE 266
AIK K + V T + RE+ SL R +N ++ + ++++++ + +++V EF +
Sbjct: 64 AIKSMKKKLAKVSDATRL-----REVHSLLRLSENENIVNIFDLYIDQFRCLHIVMEFLD 118
Query: 267 HDLLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGC- 325
+L Q+I + L ++ IM QI G++++H N HRD+KP NI+++ +
Sbjct: 119 CNLYQLISTRKNDPLTL---EQVQDIMRQIFKGLNHIHTNGFFHRDMKPENILISSNSDS 175
Query: 326 ----VKIGDLGLARKFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIF 381
VKI D GLAR+ N+ + YT + + T WYRAPEL+L +Y+ +D++A GC+
Sbjct: 176 SSFNVKIADFGLAREINS--RPPYT--EYVSTRWYRAPELLLRDSYYSFPVDIYAAGCMA 231
Query: 382 AELIGLRPIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHK----------IWPNIDS 431
E+ L+PIF G + +Q K+ E++GSPD + IW +
Sbjct: 232 FEIATLQPIFPGND-----------DFDQLYKMCEILGSPDEQSQNTGDKGGGIWDRAEL 280
Query: 432 YPEYLQLAKMPK-----YRDNLTAWYQTAGGKDKTALDILYRLLQYDPIKRIDAIDALD 485
L ++ +PK + D + + A +L +LL++DP KR A LD
Sbjct: 281 LANKLGIS-LPKMAPLDFGDLFSPPWNLA------FASMLSQLLKWDPAKRPTAEMCLD 332
>SPAC1687.15 [G] KOG0658 Glycogen synthase kinase-3
Length = 387
Score = 109 bits (272), Expect = 1e-23
Identities = 76/269 (28%), Positives = 142/269 (52%), Gaps = 35/269 (13%)
Query: 232 REMSLCRELDNNHLTKLVEIFL------EKKSIYMVSEFAEHDLLQIIHFHSHPEKRLIP 285
RE+ + R + + ++ L+ + ++ + +V EF + + ++ +K +P
Sbjct: 72 RELQIMRIMKHPNIVDLIAYYYTTGDNSDEVYLNLVLEFMPETIYRASRLYTR-QKLSMP 130
Query: 286 PRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVD-GCVKIGDLGLARKFNNMVQTL 344
+K ++Q+L ++Y+H + I HRD+KP N+++ + G +K+ D G A+ L
Sbjct: 131 MLEVKLYIYQLLRSLAYIHASGICHRDIKPQNLLLDPENGILKLCDFGSAK-------IL 183
Query: 345 YTGD---KVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELIGLRPIFKGEEAKMESK 401
G+ I + +YRAPELI GA YT AID+W+ GC+ AEL+ P+F GE
Sbjct: 184 VAGEPNVSYICSRYYRAPELIFGATDYTHAIDIWSTGCVMAELMLGHPLFPGESG----- 238
Query: 402 KSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPKYRDN-LTAWYQTAGGKDK 460
+Q +I++++G+P + ++ P Y++ + P+ R L+ + + D
Sbjct: 239 ------IDQLVEIIKILGTPSREQIKTMN--PNYME-HRFPQIRPQPLSRVFSRSVPLD- 288
Query: 461 TALDILYRLLQYDPIKRIDAIDALDHVYF 489
ALD+L ++LQY P R+ A +A+ H +F
Sbjct: 289 -ALDLLSKMLQYTPTDRLTAAEAMCHPFF 316
>Hs22051130 [G] KOG0658 Glycogen synthase kinase-3
Length = 483
Score = 109 bits (272), Expect = 1e-23
Identities = 82/271 (30%), Positives = 139/271 (51%), Gaps = 39/271 (14%)
Query: 232 REMSLCRELDNNHLTKLVEIFL---EKKS---IYMVSEFAEHDLLQIIHFHSHPEKRLIP 285
RE+ + R+LD+ ++ +L F EKK + +V E+ + ++ H K IP
Sbjct: 159 RELQIMRKLDHCNIVRLRYFFYSSGEKKDELYLNLVLEYVPETVYRVAR-HFTKAKLTIP 217
Query: 286 PRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGCV-KIGDLGLARKFNNMVQTL 344
+K M+Q+ ++Y+H + HRD+KP N++V D V K+ D G A++ L
Sbjct: 218 ILYVKVYMYQLFRSLAYIHSQGVCHRDIKPQNLLVDPDTAVLKLCDFGSAKQ-------L 270
Query: 345 YTGD---KVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELIGLRPIFKGEEAKMESK 401
G+ I + +YRAPELI GA YT +ID+W+ GC+ AEL+ +PIF G+
Sbjct: 271 VRGEPNVSYICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSG----- 325
Query: 402 KSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPKYRDNLTAWYQTAGGKDKT 461
+Q +I++V+G+P + ++ P Y + K P+ + + W T K +T
Sbjct: 326 ------VDQLVEIIKVLGTPTREQIREMN--PNYTEF-KFPQIKAH--PW--TKVFKSRT 372
Query: 462 ---ALDILYRLLQYDPIKRIDAIDALDHVYF 489
A+ + LL+Y P R+ ++A H +F
Sbjct: 373 PPEAIALCSSLLEYTPSSRLSPLEACAHSFF 403
>Hs11995474 [G] KOG0658 Glycogen synthase kinase-3
Length = 483
Score = 109 bits (272), Expect = 1e-23
Identities = 82/271 (30%), Positives = 139/271 (51%), Gaps = 39/271 (14%)
Query: 232 REMSLCRELDNNHLTKLVEIFL---EKKS---IYMVSEFAEHDLLQIIHFHSHPEKRLIP 285
RE+ + R+LD+ ++ +L F EKK + +V E+ + ++ H K IP
Sbjct: 159 RELQIMRKLDHCNIVRLRYFFYSSGEKKDELYLNLVLEYVPETVYRVAR-HFTKAKLTIP 217
Query: 286 PRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGCV-KIGDLGLARKFNNMVQTL 344
+K M+Q+ ++Y+H + HRD+KP N++V D V K+ D G A++ L
Sbjct: 218 ILYVKVYMYQLFRSLAYIHSQGVCHRDIKPQNLLVDPDTAVLKLCDFGSAKQ-------L 270
Query: 345 YTGD---KVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELIGLRPIFKGEEAKMESK 401
G+ I + +YRAPELI GA YT +ID+W+ GC+ AEL+ +PIF G+
Sbjct: 271 VRGEPNVSYICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSG----- 325
Query: 402 KSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPKYRDNLTAWYQTAGGKDKT 461
+Q +I++V+G+P + ++ P Y + K P+ + + W T K +T
Sbjct: 326 ------VDQLVEIIKVLGTPTREQIREMN--PNYTEF-KFPQIKAH--PW--TKVFKSRT 372
Query: 462 ---ALDILYRLLQYDPIKRIDAIDALDHVYF 489
A+ + LL+Y P R+ ++A H +F
Sbjct: 373 PPEAIALCSSLLEYTPSSRLSPLEACAHSFF 403
>YBL016w [T] KOG0660 Mitogen-activated protein kinase
Length = 353
Score = 108 bits (271), Expect = 2e-23
Identities = 82/301 (27%), Positives = 147/301 (48%), Gaps = 48/301 (15%)
Query: 232 REMSLCRELDNNHLTKLVEI-----FLEKKSIYMVSEFAEHDLLQIIHFHSHPEKRLIPP 286
RE+ + + + ++ + I F +Y++ E + DL ++I +++
Sbjct: 58 REIKILKHFKHENIITIFNIQRPDSFENFNEVYIIQELMQTDLHRVI------STQMLSD 111
Query: 287 RMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGCVKIGDLGLARKFNNMV--QTL 344
++ ++Q L V LH + ++HRDLKP+N+++ + +K+ D GLAR + +
Sbjct: 112 DHIQYFIYQTLRAVKVLHGSNVIHRDLKPSNLLINSNCDLKVCDFGLARIIDESAADNSE 171
Query: 345 YTGDK-----VIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELIGLRPIFKGEEAKME 399
TG + + T WYRAPE++L + Y+ A+D+W+ GCI AEL RPIF G + +
Sbjct: 172 PTGQQSGMTEYVATRWYRAPEVMLTSAKYSRAMDVWSCGCILAELFLRRPIFPGRDYR-- 229
Query: 400 SKKSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPKYRDNLTAWYQTAGGK- 458
+Q I ++G+ P+ D+ ++ + +Y +L + K
Sbjct: 230 ---------HQLLLIFGIIGT------PHSDNDLRCIESPRAREYIKSLPMYPAAPLEKM 274
Query: 459 ----DKTALDILYRLLQYDPIKRIDAIDALDHVYF-TNGDP-------PVCENVFEGLNY 506
+ +D+L R+L +DP KRI A +AL+H Y T DP P+ + FE +Y
Sbjct: 275 FPRVNPKGIDLLQRMLVFDPAKRITAKEALEHPYLQTYHDPNDEPEGEPIPPSFFEFDHY 334
Query: 507 K 507
K
Sbjct: 335 K 335
>HsM4504163 [G] KOG0658 Glycogen synthase kinase-3
Length = 420
Score = 108 bits (269), Expect = 3e-23
Identities = 77/269 (28%), Positives = 140/269 (51%), Gaps = 35/269 (13%)
Query: 232 REMSLCRELDNNHLTKLVEIFL----EKKSIYM--VSEFAEHDLLQIIHFHSHPEKRLIP 285
RE+ + R+LD+ ++ +L F +K +Y+ V ++ + ++ +S K+ +P
Sbjct: 96 RELQIMRKLDHCNIVRLRYFFYSSGEKKDEVYLNLVLDYVPETVYRVARHYSRA-KQTLP 154
Query: 286 PRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGCV-KIGDLGLARKFNNMVQTL 344
+K M+Q+ ++Y+H I HRD+KP N+++ D V K+ D G A++ L
Sbjct: 155 VIYVKLYMYQLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQ-------L 207
Query: 345 YTGD---KVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELIGLRPIFKGEEAKMESK 401
G+ I + +YRAPELI GA YT +ID+W+ GC+ AEL+ +PIF G+
Sbjct: 208 VRGEPNVSYICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSG----- 262
Query: 402 KSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPKYRDNLTAWYQTAGGK-DK 460
+Q +I++V+G+P + ++ P Y + K P+ + + W + +
Sbjct: 263 ------VDQLVEIIKVLGTPTREQIREMN--PNYTEF-KFPQIKAH--PWTKVFRPRTPP 311
Query: 461 TALDILYRLLQYDPIKRIDAIDALDHVYF 489
A+ + RLL+Y P R+ ++A H +F
Sbjct: 312 EAIALCSRLLEYTPTARLTPLEACAHSFF 340
>Hs20986516 [T] KOG0660 Mitogen-activated protein kinase
Length = 307
Score = 107 bits (268), Expect = 4e-23
Identities = 69/229 (30%), Positives = 119/229 (51%), Gaps = 33/229 (14%)
Query: 209 AIKKFKTEREGVEHYTGISQSACREMSLCRELDNNHLTKLVEIFLEKKS------IYMVS 262
A+KK + + H ++ RE+ L + + + ++ L+++F +S +Y+V+
Sbjct: 51 AVKKLSRPFQSIIH----AKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVT 106
Query: 263 EFAEHDLLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTV 322
DL I+ + + + +++QIL G+ Y+H I+HRDLKP+N+ V
Sbjct: 107 HLMGADLNNIVKCQKLTDDHV------QFLIYQILRGLKYIHSADIIHRDLKPSNLAVNE 160
Query: 323 DGCVKIGDLGLARKFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFA 382
D +KI D GLAR ++ + TG + T WYRAPE++L HY +D+W+VGCI A
Sbjct: 161 DCELKILDFGLARHTDDEM----TG--YVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMA 214
Query: 383 ELIGLRPIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHKIWPNIDS 431
EL+ R +F G + +Q + IL ++G+P ++ I S
Sbjct: 215 ELLTGRTLFPGTD-----------HIDQLKLILRLVGTPGAELLKKISS 252
>At3g05840 [G] KOG0658 Glycogen synthase kinase-3
Length = 409
Score = 107 bits (268), Expect = 4e-23
Identities = 85/269 (31%), Positives = 140/269 (51%), Gaps = 35/269 (13%)
Query: 232 REMSLCRELDNNHLTKLVEIFL---EKKSIYM--VSEFAEHDLLQIIHFHSHPEKRLIPP 286
RE+ R LD+ ++ L F EK +Y+ V E+ + ++I ++ +R+ P
Sbjct: 113 RELQTMRLLDHPNVVSLKHCFFSTTEKDELYLNLVLEYVPETVHRVIKHYNKLNQRM-PL 171
Query: 287 RMLKSIMWQILDGVSYLHQN-WILHRDLKPANIMVTVDGC-VKIGDLGLARKFNNMVQTL 344
+K +QI +SY+H+ + HRD+KP N++V VK+ D G A+ L
Sbjct: 172 VYVKLYTYQIFRSLSYIHRCIGVCHRDIKPQNLLVNPHTHQVKLCDFGSAK-------VL 224
Query: 345 YTGDKVIVTI---WYRAPELILGARHYTPAIDLWAVGCIFAELIGLRPIFKGEEAKMESK 401
G+ I I +YRAPELI GA YT AID+W+ GC+ AEL+ +P+F GE
Sbjct: 225 VKGEPNISYICSRYYRAPELIFGATEYTTAIDVWSAGCVLAELLLGQPLFPGESG----- 279
Query: 402 KSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPKYRDNLTAWYQTAGGK-DK 460
+Q +I++V+G+P + ++ P Y + K P+ + + W++ +
Sbjct: 280 ------VDQLVEIIKVLGTPTREEIKCMN--PNYTEF-KFPQIKAH--PWHKIFHKRMPP 328
Query: 461 TALDILYRLLQYDPIKRIDAIDALDHVYF 489
A+D++ RLLQY P R A+D+L H +F
Sbjct: 329 EAVDLVSRLLQYSPNLRCAALDSLVHPFF 357
>At1g57700 [D] KOG0600 Cdc2-related protein kinase
Length = 686
Score = 107 bits (267), Expect = 5e-23
Identities = 77/261 (29%), Positives = 124/261 (47%), Gaps = 29/261 (11%)
Query: 232 REMSLCRELDNNHLTKLVEIFLEKKS--IYMVSEFAEHDLLQIIHFHSHPEKRLIPPRML 289
RE+ + R L++ ++ KL + + K S +Y++ E+ +HDL + P +
Sbjct: 192 REIIILRRLNHPNVMKLEGLIISKASGSMYLIFEYMDHDLAGLAS----------TPGIK 241
Query: 290 KSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGCVKIGDLGLARKFNNMVQTLYTGDK 349
S Q+L G+ + H +LHRD+K +N+++ + +KIGD GL+ + + T
Sbjct: 242 FSQAQQLLLGLEHCHSCGVLHRDIKCSNLLLDRNNNLKIGDFGLSNFYRGQRKQPLTSR- 300
Query: 350 VIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELIGLRPIFKGEEAKMESKKSVLFQAN 409
+VT+WYR PEL+LG+ Y +DLW+ GCI AEL +P+ G +
Sbjct: 301 -VVTLWYRPPELLLGSTDYGVTVDLWSTGCILAELFTGKPLLPGRT-----------EVE 348
Query: 410 QFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPKYRDNLTAWYQTAGGKDKTALDILYRL 469
Q KI ++ GSP + W S + + K A T +AL +L L
Sbjct: 349 QMHKIFKLCGSPSEEYWRR--SRLRHATIFKPQHPYKRCVA--DTFKDLPSSALALLEVL 404
Query: 470 LQYDPIKRIDAIDALDHVYFT 490
L +P R A AL +FT
Sbjct: 405 LAVEPDARGTASSALQSEFFT 425
>At1g06390 [G] KOG0658 Glycogen synthase kinase-3
Length = 407
Score = 107 bits (267), Expect = 5e-23
Identities = 80/269 (29%), Positives = 138/269 (50%), Gaps = 35/269 (13%)
Query: 232 REMSLCRELDNNHLTKLVEIFLEKKS-----IYMVSEFAEHDLLQIIHFHSHPEKRLIPP 286
RE+ L R +D+ ++ L F S + +V E+ L +++ ++ +R+ P
Sbjct: 110 RELQLMRPMDHPNVISLKHCFFSTTSRDELFLNLVMEYVPETLYRVLRHYTSSNQRM-PI 168
Query: 287 RMLKSIMWQILDGVSYLHQ-NWILHRDLKPANIMVT-VDGCVKIGDLGLARKFNNMVQTL 344
+K +QI G++Y+H + HRD+KP N++V + VK+ D G A+ L
Sbjct: 169 FYVKLYTYQIFRGLAYIHTVPGVCHRDVKPQNLLVDPLTHQVKLCDFGSAK-------VL 221
Query: 345 YTGDKVIVTI---WYRAPELILGARHYTPAIDLWAVGCIFAELIGLRPIFKGEEAKMESK 401
G+ I I +YRAPELI GA YT +ID+W+ GC+ AEL+ +P+F GE +
Sbjct: 222 VKGEPNISYICSRYYRAPELIFGATEYTASIDIWSAGCVLAELLLGQPLFPGENS----- 276
Query: 402 KSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPKYRDNLTAWYQTAGGK-DK 460
+Q +I++V+G+P + ++ P Y + P+ + + W++ +
Sbjct: 277 ------VDQLVEIIKVLGTPTREEIRCMN--PNYTDF-RFPQIKAH--PWHKVFHKRMPP 325
Query: 461 TALDILYRLLQYDPIKRIDAIDALDHVYF 489
A+D+ RLLQY P R A++A H +F
Sbjct: 326 EAIDLASRLLQYSPSLRCTALEACAHPFF 354
>At5g26751 [G] KOG0658 Glycogen synthase kinase-3
Length = 413
Score = 107 bits (266), Expect = 7e-23
Identities = 85/269 (31%), Positives = 139/269 (51%), Gaps = 35/269 (13%)
Query: 232 REMSLCRELDNNHLTKLVEIFL---EKKSIYM--VSEFAEHDLLQIIHFHSHPEKRLIPP 286
RE+ R LD+ ++ L F EK +Y+ V E+ + ++I ++ +R+ P
Sbjct: 109 RELQTMRLLDHPNVVSLKHCFFSTTEKDELYLNLVLEYVPETVHRVIKHYNKLNQRM-PL 167
Query: 287 RMLKSIMWQILDGVSYLHQN-WILHRDLKPANIMVTVDGC-VKIGDLGLARKFNNMVQTL 344
+K +QI +SY+H+ + HRD+KP N++V VK+ D G A+ L
Sbjct: 168 IYVKLYTYQIFRALSYIHRCIGVCHRDIKPQNLLVNPHTHQVKLCDFGSAK-------VL 220
Query: 345 YTGDKVIVTI---WYRAPELILGARHYTPAIDLWAVGCIFAELIGLRPIFKGEEAKMESK 401
G+ I I +YRAPELI GA YT AID+W+ GC+ AEL+ +P+F GE
Sbjct: 221 VKGEPNISYICSRYYRAPELIFGATEYTTAIDVWSAGCVLAELLLGQPLFPGESG----- 275
Query: 402 KSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPKYRDNLTAWYQTAGGK-DK 460
+Q +I++V+G+P + ++ P Y + K P+ + + W++ +
Sbjct: 276 ------VDQLVEIIKVLGTPTREEIKCMN--PNYTEF-KFPQIKAH--PWHKIFHKRMPP 324
Query: 461 TALDILYRLLQYDPIKRIDAIDALDHVYF 489
A+D++ RLLQY P R A+D L H +F
Sbjct: 325 EAVDLVSRLLQYSPNLRSAALDTLVHPFF 353
>At3g61160 [G] KOG0658 Glycogen synthase kinase-3
Length = 431
Score = 106 bits (265), Expect = 9e-23
Identities = 85/269 (31%), Positives = 137/269 (50%), Gaps = 35/269 (13%)
Query: 232 REMSLCRELDNNHLTKLVEIFL---EKKSIYM--VSEFAEHDLLQIIHFHSHPEKRLIPP 286
RE+ + R LD+ ++ +L F EK +Y+ V E+ + + ++ + + P
Sbjct: 142 RELQIMRMLDHPNVVELKHSFFSTTEKDELYLNLVLEYVPETIYRASRSYTKMNQHM-PL 200
Query: 287 RMLKSIMWQILDGVSYLHQN-WILHRDLKPANIMVT-VDGCVKIGDLGLARKFNNMVQTL 344
++ +QI ++YLHQ + HRD+KP N++V V VKI D G A+ L
Sbjct: 201 IYIQLYTYQICRAMNYLHQVVGVCHRDIKPQNLLVNNVTHEVKICDFGSAKM-------L 253
Query: 345 YTGDKVIVTI---WYRAPELILGARHYTPAIDLWAVGCIFAELIGLRPIFKGEEAKMESK 401
G+ I I +YRAPELI GA YT AID+W+VGC+ AEL P+F GE +
Sbjct: 254 IPGEPNISYICSRYYRAPELIFGATEYTSAIDMWSVGCVMAELFLGHPLFPGETS----- 308
Query: 402 KSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPKYRDNLTAWYQTAGGK-DK 460
+Q +I++++G+P + N++ P Y K P+ + W++ +
Sbjct: 309 ------VDQLVEIIKILGTPAREEIKNMN--PRYNDF-KFPQIK--AQPWHKIFRRQVSP 357
Query: 461 TALDILYRLLQYDPIKRIDAIDALDHVYF 489
A+D+ RLLQY P R A++A H +F
Sbjct: 358 EAMDLASRLLQYSPNLRCTALEACAHPFF 386
>7290342 [G] KOG0658 Glycogen synthase kinase-3
Length = 1008
Score = 106 bits (265), Expect = 9e-23
Identities = 77/268 (28%), Positives = 142/268 (52%), Gaps = 33/268 (12%)
Query: 232 REMSLCRELDNNHLTKLVEIFL---EKKS---IYMVSEFAEHDLLQIIHFHSHPEKRLIP 285
RE+ + R+L++ ++ KL+ F EK+ + +V E+ + ++ ++ K+ IP
Sbjct: 588 RELQIMRKLEHCNIVKLLYFFYSSGEKRDEVFLNLVLEYIPETVYKVARQYAKT-KQTIP 646
Query: 286 PRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGCV-KIGDLGLARKFNNMVQTL 344
++ M+Q+ ++Y+H I HRD+KP N+++ + V K+ D G A+ Q L
Sbjct: 647 INFIRLYMYQLFRSLAYIHSLGICHRDIKPQNLLLDPETAVLKLCDFGSAK------QLL 700
Query: 345 YTGDKV--IVTIWYRAPELILGARHYTPAIDLWAVGCIFAELIGLRPIFKGEEAKMESKK 402
+ V I + +YRAPELI GA +YT ID+W+ GC+ AEL+ +PIF G+
Sbjct: 701 HGEPNVSYICSRYYRAPELIFGAINYTTKIDVWSAGCVLAELLLGQPIFPGDSG------ 754
Query: 403 SVLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPKYRDNLTAWYQTAGGKDKT- 461
+Q ++++V+G+P + ++ P Y + K P+ + + W + + T
Sbjct: 755 -----VDQLVEVIKVLGTPTREQIREMN--PNYTEF-KFPQIKSH--PWQKVFRIRTPTE 804
Query: 462 ALDILYRLLQYDPIKRIDAIDALDHVYF 489
A++++ LL+Y P RI + A H +F
Sbjct: 805 AINLVSLLLEYTPSARITPLKACAHPFF 832
>CE21401 [G] KOG0658 Glycogen synthase kinase-3
Length = 362
Score = 104 bits (260), Expect = 3e-22
Identities = 75/267 (28%), Positives = 140/267 (52%), Gaps = 31/267 (11%)
Query: 232 REMSLCRELDNNHLTKLVEIFL---EKKS---IYMVSEFAEHDLLQIIHFHSHPEKRLIP 285
RE+ + R+L++ ++ KL F EKK + ++ E+ + ++ +S +++ IP
Sbjct: 76 RELQIMRKLNHPNIVKLKYFFYSSGEKKDELYLNLILEYVPETVYRVARHYSK-QRQQIP 134
Query: 286 PRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVD-GCVKIGDLGLARKF-NNMVQT 343
+K M+Q+L ++Y+H I HRD+KP N+++ + G +K+ D G A+ N
Sbjct: 135 MIYVKLYMYQLLRSLAYIHSIGICHRDIKPQNLLIDPESGVLKLCDFGSAKYLVRNEPNV 194
Query: 344 LYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELIGLRPIFKGEEAKMESKKS 403
Y I + +YRAPELI GA +YT +ID+W+ G + AEL+ +PIF G+
Sbjct: 195 SY-----ICSRYYRAPELIFGATNYTNSIDVWSAGTVMAELLLGQPIFPGDSG------- 242
Query: 404 VLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPKYRDNLTAWYQT-AGGKDKTA 462
+Q +I++V+G+P + +++ P Y + K P+ + + W + A
Sbjct: 243 ----VDQLVEIIKVLGTPTREQIQSMN--PNYKEF-KFPQIKAH--PWNKVFRVHTPAEA 293
Query: 463 LDILYRLLQYDPIKRIDAIDALDHVYF 489
+D++ ++++Y P R A H +F
Sbjct: 294 IDLISKIIEYTPTSRPTPQAACQHAFF 320
>ECU07g1270 [G] KOG0658 Glycogen synthase kinase-3
Length = 334
Score = 104 bits (259), Expect = 4e-22
Identities = 78/266 (29%), Positives = 134/266 (50%), Gaps = 39/266 (14%)
Query: 232 REMSLCRELDNNHLTKLVEIFLEKKS-----IYMVSEFAEHDLLQIIHFHSHPEKRLIPP 286
RE+ + E+D+ ++ +LV F K+ + ++++F +L + I + R +
Sbjct: 95 RELGILMEVDHPNIVRLVSYFHTDKTSSGAYLNIITDFVGMNLEEYIKAN-----RGVET 149
Query: 287 RMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGCVKIGDLGLARKFNNMVQTLYT 346
++S+ QIL+G+ YLH+ I HRD+KP+NI++ +G VKI DLG A+ + +
Sbjct: 150 EEIRSVYRQILEGLRYLHEKNICHRDMKPSNILIDTNGLVKICDLGSAK-------VIKS 202
Query: 347 GDKVIVTI---WYRAPELILGARHYTPAIDLWAVGCIFAELIGLRPIFKGEEAKMESKKS 403
G++ I I +YRAPE +L + Y ID+W+VGC+ AE PIFKG+ +
Sbjct: 203 GERNITYICSRFYRAPENLLDYKEYDFKIDIWSVGCVIAEFRHPGPIFKGDTS------- 255
Query: 404 VLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPKYRDNLTAWYQTAGGKDKTAL 463
+ +ILE++ + P+ Q + KY L A++ D L
Sbjct: 256 ----GSTLNRILEIVRVTSDDLIGLGCLKPDLKQGVGIRKY---LEAFF-----SDPDLL 303
Query: 464 DILYRLLQYDPIKRIDAIDALDHVYF 489
++L + L + P KR A + L +F
Sbjct: 304 EVLEKSLAFSPCKRSTASELLRKQFF 329
>7291043 [T] KOG0660 Mitogen-activated protein kinase
Length = 392
Score = 104 bits (259), Expect = 4e-22
Identities = 70/253 (27%), Positives = 126/253 (49%), Gaps = 26/253 (10%)
Query: 244 HLTKLVEIFLEKKSI--YMVSEFAEHDLLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVS 301
++ +LV+IF ++ Y+V EF E DL +I ++ + +M+Q+++ +
Sbjct: 84 NIVRLVDIFKASNNLDFYLVFEFMESDLHNVIK-----RGNVLKDVHKRFVMYQLINAIK 138
Query: 302 YLHQNWILHRDLKPANIMVTVDGCVKIGDLGLARK------FNNMVQTLYTGDKVIVTIW 355
++H ++HRDLKP+NI++ +K+ D GLAR ++++ Q D V T W
Sbjct: 139 FIHSGNVIHRDLKPSNILIDSKCRLKVADFGLARTLSSRRIYDDLEQDGMLTDYV-ATRW 197
Query: 356 YRAPELILGARHYTPAIDLWAVGCIFAELIGLRPIFKGEEAKMESKKSVLFQANQFQKIL 415
YRAPE+++ +R+YT ID+W +GCI E+I +P+F+G + +K V N + +
Sbjct: 198 YRAPEILVASRNYTKGIDMWGLGCILGEMIRQKPLFQGTSTVNQIEKIVTSLPNVTKLDI 257
Query: 416 EVMGSPDHKIWPNIDSYPEYLQLAKMPKYRDNLTAWYQTAGGKDKTALDILYRLLQYDPI 475
+G P+ S L RD + + + ++ LL +P
Sbjct: 258 ASIG-------PSFGSV-----LLSRNIQRDRRYSLDEMMKNCCDDGISLVKALLVLNPH 305
Query: 476 KRIDAIDALDHVY 488
R+ A +A+ H Y
Sbjct: 306 NRLTAKEAIRHPY 318
>At2g30980 [G] KOG0658 Glycogen synthase kinase-3
Length = 412
Score = 103 bits (257), Expect = 7e-22
Identities = 78/269 (28%), Positives = 137/269 (49%), Gaps = 35/269 (13%)
Query: 232 REMSLCRELDNNHLTKLVEIFLEKKS-----IYMVSEFAEHDLLQIIHFHSHPEKRLIPP 286
RE+ L R +D+ ++ L F + + +V E+ L +++ ++ +R+ P
Sbjct: 112 RELQLMRLMDHPNVVSLKHCFFSTTTRDELFLNLVMEYVPETLYRVLKHYTSSNQRM-PI 170
Query: 287 RMLKSIMWQILDGVSYLHQN-WILHRDLKPANIMVT-VDGCVKIGDLGLARKFNNMVQTL 344
+K +QI G++Y+H + HRD+KP N++V + K+ D G A+ L
Sbjct: 171 FYVKLYTYQIFRGLAYIHTAPGVCHRDVKPQNLLVDPLTHQCKLCDFGSAK-------VL 223
Query: 345 YTGDKVIVTI---WYRAPELILGARHYTPAIDLWAVGCIFAELIGLRPIFKGEEAKMESK 401
G+ I I +YRAPELI GA YT +ID+W+ GC+ AEL+ +P+F GE +
Sbjct: 224 VKGEANISYICSRYYRAPELIFGATEYTSSIDIWSAGCVLAELLLGQPLFPGENS----- 278
Query: 402 KSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPKYRDNLTAWYQTAGGK-DK 460
+Q +I++V+G+P + ++ P Y + P+ + + W++ +
Sbjct: 279 ------VDQLVEIIKVLGTPTREEIRCMN--PNYTDF-RFPQIKAH--PWHKVFHKRMPP 327
Query: 461 TALDILYRLLQYDPIKRIDAIDALDHVYF 489
A+D+ RLLQY P R A++A H +F
Sbjct: 328 EAIDLASRLLQYSPSLRCTALEACAHPFF 356
>Hs17461944 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 385
Score = 103 bits (256), Expect = 1e-21
Identities = 62/195 (31%), Positives = 109/195 (55%), Gaps = 18/195 (9%)
Query: 206 QFYAIKKF-KTEREGVEHYTGISQSACREMSLCRELDNNHLTKLVEIFLEKKSIYMVSEF 264
Q A+KKF ++E + V + + A RE+ + ++L + +L L+E+F K+ +++V E+
Sbjct: 28 QVVAVKKFVESEDDPV-----VKKIALREIRMLKQLKHPNLVNLIEVFRRKRKMHLVFEY 82
Query: 265 AEHDLLQIIHFHSHPEKRLIPPRMLKSI--MWQILDGVSYLHQNWILHRDLKPANIMVTV 322
+H LL + + + L+S+ ++ + + +HRD+KP NI++T
Sbjct: 83 CDHTLLNELERNPNGMDSDSIVGRLRSVADRSRLAPKNNQIMILQCIHRDIKPENILITK 142
Query: 323 DGCVKIGDLGLARKFNNMVQTLYTGD---KVIVTIWYRAPELILGARHYTPAIDLWAVGC 379
G +KI D G A Q L GD + T WYRAPEL++G Y ++D+WA+GC
Sbjct: 143 QGIIKICDFGFA-------QILIPGDAYTDYVATRWYRAPELLVGDTQYGSSVDIWAIGC 195
Query: 380 IFAELIGLRPIFKGE 394
+FAEL+ +P++ G+
Sbjct: 196 VFAELLTGQPLWPGK 210
>Hs19923407 [D] KOG0591 NIMA (never in mitosis)-related G2-specific
serine/threonine protein kinase
Length = 313
Score = 102 bits (253), Expect = 2e-21
Identities = 56/174 (32%), Positives = 100/174 (57%), Gaps = 6/174 (3%)
Query: 228 QSACREMSLCRELDNNHLTKLVEIFLEKKSIYMVSEFAEH-DLLQIIHFHSHPEKRLIPP 286
Q +E+ L ++L++ ++ K ++ F+E + +V E A+ DL Q+I + +KRLIP
Sbjct: 88 QDCVKEIGLLKQLNHPNIIKYLDSFIEDNELNIVLELADAGDLSQMIKYFKK-QKRLIPE 146
Query: 287 RMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGCVKIGDLGLARKFNNMVQTLYT 346
R + Q+ V ++H ++HRD+KPAN+ +T G VK+GDLGL R F++ ++
Sbjct: 147 RTVWKYFVQLCSAVEHMHSRRVMHRDIKPANVFITATGVVKLGDLGLGRFFSSETTAAHS 206
Query: 347 GDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELIGLRPIFKGEEAKMES 400
++ T +Y +PE I Y D+W++GC+ E+ L+ F G++ + S
Sbjct: 207 ---LVGTPYYMSPERI-HENGYNFKSDIWSLGCLLYEMAALQSPFYGDKMNLFS 256
>At1g57870 [G] KOG0658 Glycogen synthase kinase-3
Length = 420
Score = 102 bits (253), Expect = 2e-21
Identities = 83/269 (30%), Positives = 136/269 (49%), Gaps = 35/269 (13%)
Query: 232 REMSLCRELDNNHLTKLVEIFL---EKKSIYM--VSEFAEHDLLQIIHFHSHPEKRLIPP 286
RE+ + + LD+ ++ L F E + +Y+ V EF + + +S + L+P
Sbjct: 122 RELQIMQMLDHPNVVCLKHSFYSRTENEEVYLNLVLEFVPETVNRTARSYSRMNQ-LMPL 180
Query: 287 RMLKSIMWQILDGVSYLHQNW-ILHRDLKPANIMVTVDGC-VKIGDLGLARKFNNMVQTL 344
+K +QI G++YLH + HRD+KP N++V +KI D G A+ L
Sbjct: 181 IYVKLYTYQICRGLAYLHNCCGLCHRDIKPQNLLVNPHTHQLKICDFGSAK-------VL 233
Query: 345 YTGDKVIVTI---WYRAPELILGARHYTPAIDLWAVGCIFAELIGLRPIFKGEEAKMESK 401
G+ I I +YRAPELI GA YT AID+W+ GC+ AEL+ +P+F GE
Sbjct: 234 VKGEPNISYICSRYYRAPELIFGATEYTTAIDIWSTGCVMAELLLGQPLFPGESG----- 288
Query: 402 KSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPKYRDNLTAWYQTAGGK-DK 460
+Q +I++V+G+P + ++ P Y + K P+ + + W++ +
Sbjct: 289 ------VDQLVEIIKVLGTPTREEIKCMN--PNYTEF-KFPQIKPH--PWHKVFQKRLPP 337
Query: 461 TALDILYRLLQYDPIKRIDAIDALDHVYF 489
A+D+L R QY P R A++A H +F
Sbjct: 338 EAVDLLCRFFQYSPNLRCTAVEACIHPFF 366
>Hs16306492 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 240
Score = 101 bits (252), Expect = 3e-21
Identities = 49/143 (34%), Positives = 84/143 (58%), Gaps = 15/143 (10%)
Query: 351 IVTIWYRAPELILGARHYTPAIDLWAVGCIFAELIGLRPIFKGEEAKMESKKSVLFQANQ 410
+VT+WYR+PE++LG+ Y+ +D+W++G IFAEL +P+F G+ + +Q
Sbjct: 107 VVTLWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDS-----------EIDQ 155
Query: 411 FQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPKYRDNLTAWYQTAGGKDKTALDILYRLL 470
+I +G+P++++WP ++S +Y PK++ A + D+ LD+L ++L
Sbjct: 156 LFRIFRALGTPNNEVWPEVESLQDYKN--TFPKWKPGSLASH--VKNLDENGLDLLSKML 211
Query: 471 QYDPIKRIDAIDALDHVYFTNGD 493
YDP KRI AL+H YF + D
Sbjct: 212 IYDPAKRISGKMALNHPYFNDLD 234
>At1g09840 [G] KOG0658 Glycogen synthase kinase-3
Length = 421
Score = 100 bits (250), Expect = 5e-21
Identities = 79/269 (29%), Positives = 136/269 (50%), Gaps = 35/269 (13%)
Query: 232 REMSLCRELDNNHLTKLVEIFLEK---KSIYM--VSEFAEHDLLQIIHFHSHPEKRLIPP 286
RE+ + + LD+ + L F + + +Y+ V EF + ++ +S + L+P
Sbjct: 123 RELQIMQMLDHPNAVALKHSFFSRTDNEEVYLNLVLEFVPETVNRVARSYSRTNQ-LMPL 181
Query: 287 RMLKSIMWQILDGVSYLHQNW-ILHRDLKPANIMVTVDGC-VKIGDLGLARKFNNMVQTL 344
+K +QI ++Y+H ++ + HRD+KP N++V +KI D G A+ L
Sbjct: 182 IYVKLYTYQICRALAYIHNSFGLCHRDIKPQNLLVNPHTHQLKICDFGSAK-------VL 234
Query: 345 YTGD---KVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELIGLRPIFKGEEAKMESK 401
G+ I + +YRAPELI GA YT AID+W+ GC+ AEL+ +P+F GE
Sbjct: 235 VKGEPNVSYICSRYYRAPELIFGASEYTTAIDIWSTGCVMAELLLGQPLFPGESG----- 289
Query: 402 KSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPKYRDNLTAWYQTAGGK-DK 460
+Q +I++V+G+P + ++ P Y + K P+ + + W++ +
Sbjct: 290 ------VDQLVEIIKVLGTPTREEIKCMN--PNYTEF-KFPQIKPH--PWHKVFQKRLPP 338
Query: 461 TALDILYRLLQYDPIKRIDAIDALDHVYF 489
A+D+L R QY P R A++A H F
Sbjct: 339 EAVDLLCRFFQYSPNLRCTALEACIHPLF 367
>CE08727 [G] KOG0658 Glycogen synthase kinase-3
Length = 367
Score = 99.8 bits (247), Expect = 1e-20
Identities = 60/191 (31%), Positives = 106/191 (55%), Gaps = 18/191 (9%)
Query: 209 AIKKFKTEREGVEHYTGISQSACREMSLCRELDNNHLTKLVEIFL--EKKSIYMVSEFAE 266
AIKK K + + RE+++ E+D+ ++ +L+ ++ ++ + V EF
Sbjct: 64 AIKKIKVD----------DRFKSRELTIMHEMDHPNIIRLLYYYVMQQENCLNFVMEFMP 113
Query: 267 HDLLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTV-DGC 325
DL + +H +K++ P +K M+Q+L G+ +LH + I+HRD+KP N++V +G
Sbjct: 114 KDLAYVHRQFAHNDKQM-PAYSIKLYMFQLLRGIGFLHLHNIVHRDIKPKNLLVDESNGI 172
Query: 326 VKIGDLGLARKFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELI 385
+KI D G A++ + I + +YRAPELI G+++Y +ID W+VG + EL+
Sbjct: 173 LKICDFGSAKRLEKNEPNI----TYICSRYYRAPELIFGSKNYDTSIDTWSVGTVVGELL 228
Query: 386 GLRPIFKGEEA 396
PIF + A
Sbjct: 229 HNSPIFLADSA 239
>YNL307c [G] KOG0658 Glycogen synthase kinase-3
Length = 375
Score = 99.4 bits (246), Expect = 1e-20
Identities = 74/266 (27%), Positives = 130/266 (48%), Gaps = 25/266 (9%)
Query: 232 REMSLCRELDNNHLTKLVEIFL-----EKKSIYMVSEFAEHDLLQIIHFHSHPEKRLIPP 286
RE+ + R D+ ++ KL F + K ++ + LQI K +P
Sbjct: 79 RELQILRIADHPNIVKLQYFFTHLSPQDNKVYQHLAMECLPETLQIEINRYVTNKLEMPL 138
Query: 287 RMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVD-GCVKIGDLGLARKFNNMVQTLY 345
+ ++ +QI G+ YLH + HRD+KP+N++V + G +KI D G A+K + ++
Sbjct: 139 KHIRLYTYQIARGMLYLHGLGVCHRDIKPSNVLVDPETGVLKICDFGSAKKLEHNQPSI- 197
Query: 346 TGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELIGLRPIFKGEEAKMESKKSVL 405
I + +YRAPELI+G YT ID+W +GC+ E++ + IF+G+E +
Sbjct: 198 ---SYICSRFYRAPELIIGCTQYTTQIDIWGLGCVMGEMLIGKAIFQGQEPLL------- 247
Query: 406 FQANQFQKILEVMGSPDHKIWPNIDSYPEY-LQLAKMPKYRDNLTAWYQT-AGGKDKTAL 463
Q ++I +++G PD + S P Y L P + + ++ G +
Sbjct: 248 ----QLREIAKLLGPPDKRF--IFFSNPAYDGPLFSKPLFSGSSQQRFEKYFGHSGPDGI 301
Query: 464 DILYRLLQYDPIKRIDAIDALDHVYF 489
D+L ++L Y+P +R+ L H +F
Sbjct: 302 DLLMKILVYEPQQRLSPRRILAHQFF 327
>SPBC8D2.19 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 559
Score = 98.2 bits (243), Expect = 3e-20
Identities = 62/206 (30%), Positives = 109/206 (52%), Gaps = 29/206 (14%)
Query: 245 LTKLVEIFLEK-KSIYMVSEFAEHDLLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYL 303
L L+E F++ ++I++V EF + +L Q+ + RL +I+ QI+ G+ ++
Sbjct: 85 LIDLLETFMDPYRNIFLVMEFMDCNLFQLF---KRRQGRLFTKETAFNILLQIISGIEHI 141
Query: 304 HQNWILHRDLKPANIMV--------TVDGCVKIGDLGLAR-KFNNMVQTLYTGDKVIVTI 354
H++ +HRD+KP NI+V + +K+GD GLAR ++ T Y + T
Sbjct: 142 HKHGFMHRDIKPENILVKRISPKPISSRYSIKLGDFGLARPSVSSDPLTEY-----VSTR 196
Query: 355 WYRAPELILGARHYTPAIDLWAVGCIFAELIGLRPIFKGEEAKMESKKSVLFQANQFQKI 414
WYRAPEL+L + Y ++DL+A GCI E+ L+P+F G + +Q ++
Sbjct: 197 WYRAPELLLRSGSYNHSVDLYAFGCIVFEIYSLKPLFPGRN-----------ETDQLNRV 245
Query: 415 LEVMGSPDHKIWPNIDSYPEYLQLAK 440
E++G+P + + + +LAK
Sbjct: 246 CEILGNPGIDELDTLHYWSQAKELAK 271
>Hs19424132 [D] KOG0591 NIMA (never in mitosis)-related G2-specific
serine/threonine protein kinase
Length = 302
Score = 98.2 bits (243), Expect = 3e-20
Identities = 52/169 (30%), Positives = 94/169 (54%), Gaps = 4/169 (2%)
Query: 232 REMSLCRELDNNHLTKLVEIFLEKKSIYMVSEFAEHDLLQIIHFHSHPEKRLIPPRMLKS 291
+E+ L ++L++ ++ K F+E + +V E A+ L + H +KRLIP R +
Sbjct: 81 KEIDLLKQLNHPNVIKYYASFIEDNELNIVLELADAGDLSRMIKHFKKQKRLIPERTVWK 140
Query: 292 IMWQILDGVSYLHQNWILHRDLKPANIMVTVDGCVKIGDLGLARKFNNMVQTLYTGDKVI 351
Q+ + ++H ++HRD+KPAN+ +T G VK+GDLGL R F++ ++ ++
Sbjct: 141 YFVQLCSALEHMHSRRVMHRDIKPANVFITATGVVKLGDLGLGRFFSSKTTAAHS---LV 197
Query: 352 VTIWYRAPELILGARHYTPAIDLWAVGCIFAELIGLRPIFKGEEAKMES 400
T +Y +PE I Y D+W++GC+ E+ L+ F G++ + S
Sbjct: 198 GTPYYMSPERI-HENGYNFKSDIWSLGCLLYEMAALQSPFYGDKMNLYS 245
>At5g14640 [G] KOG0658 Glycogen synthase kinase-3
Length = 408
Score = 98.2 bits (243), Expect = 3e-20
Identities = 82/269 (30%), Positives = 135/269 (49%), Gaps = 37/269 (13%)
Query: 232 REMSLCRELDNNHLTKLVEIFL---EKKSIYM--VSEFAEHDLLQIIHFHSHPEKRLIPP 286
RE+ R LD+ ++ L F EK +Y+ V E+ + ++ +S +R+ P
Sbjct: 114 RELQTMRLLDHPNVVSLKHCFFSTTEKDELYLNLVLEYVPETVYRVSKHYSRANQRM-PI 172
Query: 287 RMLKSIMWQILDGVSYLHQN-WILHRDLKPANIMVTVDGC-VKIGDLGLARKFNNMVQTL 344
+K +QI ++Y+H + HRD+KP N++V VK+ D G A+ L
Sbjct: 173 IYVKLYTYQICRALAYIHGGVGVCHRDIKPQNLLVNPHTHQVKLCDFGSAK-------VL 225
Query: 345 YTGDKVIVTI---WYRAPELILGARHYTPAIDLWAVGCIFAELIGLRPIFKGEEAKMESK 401
G+ I I +YRAPELI GA YT ID+W+ GC+ AEL+ +P+F GE
Sbjct: 226 VKGEPNISYICSRYYRAPELIFGATEYTTTIDIWSAGCVLAELLLGQPLFPGESG----- 280
Query: 402 KSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPKYRDNLTAWYQTAGGK-DK 460
+Q +I++V+G+P + ++ P Y + K P+ + + W++ +
Sbjct: 281 ------VDQLVEIIKVLGTPTREEIKCMN--PNYTEF-KFPQIKAH--PWHKIFHKRTPP 329
Query: 461 TALDILYRLLQYDPIKRIDAIDALDHVYF 489
A+D++ RLLQY P R A A+ H +F
Sbjct: 330 EAVDLVSRLLQYSPNLRSTA--AIVHPFF 356
>YMR139w [G] KOG0658 Glycogen synthase kinase-3
Length = 370
Score = 97.8 bits (242), Expect = 4e-20
Identities = 74/268 (27%), Positives = 135/268 (49%), Gaps = 34/268 (12%)
Query: 232 REMSLCRELDNNHLTKLVEIFLEKKS-----IYMVSEFAEHDLLQIIHFHSH---PEKRL 283
RE+ + + L + ++ L F E+ S + ++ E+ L Q + H P RL
Sbjct: 79 RELEIMKMLSHINIIDLKYFFYERDSQDEIYLNLILEYMPQSLYQRLRHFVHQRTPMSRL 138
Query: 284 IPPRMLKSIMWQILDGVSYLHQNW-ILHRDLKPANIMVTVDG-CVKIGDLGLARKFNNMV 341
+K M+Q+ ++YLH + HRD+KP N++V + +K+ D G A++
Sbjct: 139 ----EIKYYMFQLFKSLNYLHHFANVCHRDIKPQNLLVDPETWSLKLCDFGSAKQLKPTE 194
Query: 342 QTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELIGLRPIFKGEEAKMESK 401
+ I + +YRAPELI GA +YT ID+W+ GC+ AEL+ +P+F GE
Sbjct: 195 PNV----SYICSRYYRAPELIFGATNYTNQIDIWSSGCVMAELLLGQPMFPGESG----- 245
Query: 402 KSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPKYRDNLTAWYQTAGGKDKT 461
+Q +I++++G+P + +++ P Y++ K P+ + + +D
Sbjct: 246 ------IDQLVEIIKILGTPSKQEICSMN--PNYME-HKFPQIKP--IPLSRVFKKEDDQ 294
Query: 462 ALDILYRLLQYDPIKRIDAIDALDHVYF 489
++ L +L+YDP++R +A+ L YF
Sbjct: 295 TVEFLADVLKYDPLERFNALQCLCSPYF 322
>CE19219 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 381
Score = 96.3 bits (238), Expect = 1e-19
Identities = 83/302 (27%), Positives = 138/302 (45%), Gaps = 45/302 (14%)
Query: 230 ACREMSLCRELDNNHLTKLVEIFL------EKKSIYMVSEFAEHDLLQIIHFHSHPEKRL 283
A RE+ + + K+ I+ E + Y V E+ + +L I S PEK
Sbjct: 63 AQRELFCTLHIQEENFVKMYSIYTWVETVEEMREFYTVREYMDWNLRNFIL--STPEK-- 118
Query: 284 IPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGCVKIGDLGLARKFNNMVQT 343
+ +++KSI + + V Y+H + HRDLKP N+++ + KI A + + V T
Sbjct: 119 LDHKVIKSIFFDVCLAVQYMHSIRVGHRDLKPENVLINYEAIAKISGFAHANREDPFVNT 178
Query: 344 LYTGDKVIVTIWYRAPELILGAR-HYTPAIDLWAVGCIFAELIGLRPIFKGEEAKMESKK 402
Y IV +YRAPE++ + P++D+W++GCI AEL+ + +F G+
Sbjct: 179 PY-----IVQRFYRAPEILCETMDNNKPSVDIWSLGCILAELLTGKILFTGQT------- 226
Query: 403 SVLFQANQFQKILEVMGSPDHKIWPNI-DSYPEYLQLAKMPKYR--DNLTAWYQTAGGKD 459
Q +QF +I+ +G+PD + + DS + M +Y+ N+ + + D
Sbjct: 227 ----QIDQFFQIVRFLGNPDLSFYMQMPDSARTFFLGLPMNQYQKPTNIHEHFPNSLFLD 282
Query: 460 ---------KTALDILYRLLQYDPIKRIDAIDALDHVYFTNGDPPVCENVF--EGLNYKY 508
A D+L+R+L +P RID L H Y V N+ + KY
Sbjct: 283 TMISEPIDCDLARDLLFRMLVINPDDRIDIQKILVHPYLEE----VWSNIVIDNKIEEKY 338
Query: 509 PP 510
PP
Sbjct: 339 PP 340
>At4g00720 [G] KOG0658 Glycogen synthase kinase-3
Length = 472
Score = 95.5 bits (236), Expect = 2e-19
Identities = 79/274 (28%), Positives = 140/274 (50%), Gaps = 30/274 (10%)
Query: 232 REMSLCRELDNNHLTKLVEIFL---EKKSIYM--VSEFAEHDLLQIIHFHSHPEKRLIPP 286
RE+ + R D+ ++ +L F +K +Y+ V E+ + + ++ + + P
Sbjct: 178 RELQIMRLQDHPNVVRLRHSFFSTTDKDELYLNLVLEYVPETVYRASKHYTKMNQHM-PI 236
Query: 287 RMLKSIMWQILDGVSYLHQN-WILHRDLKPANIMVTVDGC-VKIGDLGLARKFNNMVQTL 344
++ +QI ++YLH+ + HRD+KP N++V +KI D G A+ M+
Sbjct: 237 IFVQLYTYQICRALNYLHRVVGVCHRDIKPQNLLVNPQTHQLKICDFGSAK----MLVPG 292
Query: 345 YTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELIGLRPIFKGEEAKMESKKSV 404
I + +YRAPELI GA YT AID+W+ GC+ AEL+ +P+F GE
Sbjct: 293 EPNISYICSRYYRAPELIFGATEYTNAIDMWSGGCVMAELLLGQPLFPGESG-------- 344
Query: 405 LFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPKYRDNLTAWYQTAGGK-DKTAL 463
+Q +I++++G+P + ++ P Y + K P+ + + W++ + A+
Sbjct: 345 ---IDQLVEIIKILGTPTREEIRCMN--PNYTEF-KFPQIKAH--PWHKIFHKRMPPEAV 396
Query: 464 DILYRLLQYDPIKRIDAIDALDHVYFTN-GDPPV 496
D++ RLLQY P R A++A H +F + DP V
Sbjct: 397 DLVSRLLQYSPNLRCTALEACAHPFFDDLRDPNV 430
>CE20405 [G] KOG0658 Glycogen synthase kinase-3
Length = 381
Score = 95.1 bits (235), Expect = 3e-19
Identities = 68/225 (30%), Positives = 108/225 (47%), Gaps = 39/225 (17%)
Query: 289 LKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVD-GCVKIGDLGLARKFNNMVQTLYTG 347
+K I+WQ+ G ++L + I HRD+KP N++ + G +KI D G + ++ T
Sbjct: 129 VKLIVWQLFRGQAHLEKADICHRDIKPQNLLYNAETGLLKISDFGSS----SIQSTKSPQ 184
Query: 348 DKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELIGLRPIFKGEEAKMESKKSVLFQ 407
VT +YR PELILG+++Y ID W+ GC+F EL+ I G+ +
Sbjct: 185 QSYHVTRYYRPPELILGSKYYGCKIDTWSCGCVFGELLKGGIILAGKSSN---------- 234
Query: 408 ANQFQKILEVMGSP-----------DHKIWPNIDSYP----------EYLQLAKMPKYRD 446
NQ + I +++G P K+ +DSY YL + +D
Sbjct: 235 -NQAEVIFDMLGYPTDSDVSSMKVSSTKLQEVLDSYEYNKSKTTADLTYLYTQTVIYQKD 293
Query: 447 NLTAWYQTAGGKD--KTALDILYRLLQYDPIKRIDAIDALDHVYF 489
T Y T +D K ++ +L ++L Y+P KR+ I+ L H YF
Sbjct: 294 RRTTVYNTKIEQDDMKESVAVLLQILVYNPNKRLSGIEILTHPYF 338
>Hs20502986 [T] KOG0660 Mitogen-activated protein kinase
Length = 277
Score = 94.4 bits (233), Expect = 4e-19
Identities = 61/220 (27%), Positives = 110/220 (49%), Gaps = 38/220 (17%)
Query: 227 SQSACREMSLCREL-DNNHLTKLVEIFLEK--KSIYMVSEF-----------------AE 266
+Q RE++L +E D+ ++ L+++ + + IY+V EF A+
Sbjct: 54 AQRTFREITLLQEFGDHPNIISLLDVIRAENDRDIYLVFEFMGCPPSPPPPTAVRTLSAD 113
Query: 267 HDLLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGCV 326
DL +I + L+ ++SI +Q+L +LH ++HRD KP+N+++ + V
Sbjct: 114 TDLNAVIR-----KGGLLQDVHVRSIFYQLLRATRFLHSGHVVHRDQKPSNVLLDANCTV 168
Query: 327 KIGDLGLARKFNNMVQTL--YTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAEL 384
K+ D GLAR ++ + + + T WYRAPE++L + YT +D+W++GCI E+
Sbjct: 169 KLCDFGLARSLGDLPEGPEDQAVTEYVATRWYRAPEVLLSSHRYTLGVDMWSLGCILGEM 228
Query: 385 IGLRPIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHK 424
+ RP+F G +Q + ILE + P +
Sbjct: 229 LRGRPLFPGTST-----------LHQLELILETIPPPSEE 257
>YOL128c [G] KOG0658 Glycogen synthase kinase-3
Length = 375
Score = 92.8 bits (229), Expect = 1e-18
Identities = 65/230 (28%), Positives = 111/230 (48%), Gaps = 24/230 (10%)
Query: 261 VSEFAEHDLLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMV 320
V E+ L IH + ++ P + +K +QIL + LH I H DLKP+NI++
Sbjct: 123 VMEYIPQTLSSEIHEYFDNGSKM-PTKHIKLYTFQILRALLTLHSMSICHGDLKPSNILI 181
Query: 321 TVD-GCVKIGDLGLARKFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGC 379
G K+ D G A++ ++ + + +YRAPEL+L ++ YT ID+W++GC
Sbjct: 182 IPSSGIAKVCDFGSAQRLDDNTEL----KTYFCSRFYRAPELLLNSKDYTTQIDIWSLGC 237
Query: 380 IFAELIGLRPIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLA 439
I E+I +P+FKG+ A +Q ++I +++G N + L
Sbjct: 238 IIGEMIKGQPLFKGDSAN-----------SQLEEIAKLLGRFPKSSIKNSQELQDSLNDQ 286
Query: 440 KMPKYRDNLTAWYQTAGGKDKTALDILYRLLQYDPIKRIDAIDALDHVYF 489
K K+ W+ + D ++ L ++L YD +R DA + H +F
Sbjct: 287 KFKKFMH----WFPSIEFFD---VEFLLKVLTYDATERCDARQLMAHEFF 329
>CE03232 [D] KOG0591 NIMA (never in mitosis)-related G2-specific
serine/threonine protein kinase
Length = 294
Score = 92.8 bits (229), Expect = 1e-18
Identities = 51/173 (29%), Positives = 95/173 (54%), Gaps = 4/173 (2%)
Query: 228 QSACREMSLCRELDNNHLTKLVEIFLEKKSIYMVSEFAEHDLLQIIHFHSHPEKRLIPPR 287
Q +E+ L ++L++ ++ + F++ + +V E AE + + H RLIP +
Sbjct: 66 QDCLKEIDLLKQLNHVNVIRYYASFIDNNQLNIVLELAEAGDMSRMIKHFKKGGRLIPEK 125
Query: 288 MLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGCVKIGDLGLARKFNNMVQTLYTG 347
+ Q+ ++++H I+HRD+KPAN+ +T +G VK+GDLGL R F++ ++
Sbjct: 126 TIWKYFVQLARALAHMHSKRIMHRDIKPANVFITGNGIVKLGDLGLGRFFSSKTTAAHS- 184
Query: 348 DKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELIGLRPIFKGEEAKMES 400
++ T +Y +PE I + Y DLW+ GC+ E+ L+ F G++ + S
Sbjct: 185 --LVGTPYYMSPERIQES-GYNFKSDLWSTGCLLYEMAALQSPFYGDKMNLYS 234
>Hs18552621 [R] KOG0597 Serine-threonine protein kinase FUSED
Length = 1315
Score = 90.1 bits (222), Expect = 8e-18
Identities = 56/163 (34%), Positives = 90/163 (54%), Gaps = 14/163 (8%)
Query: 232 REMSLCRELDNNHLTKLVEIFLEKKSIYMVSEFAEHDLLQIIHFHSHPEKRLIPPRMLKS 291
RE+ + R L + ++ +++ F K + +V+++AE +L QI+ + +P +++
Sbjct: 50 REIEIMRGLRHPNIVHMLDSFETDKEVVVVTDYAEGELFQILE-----DDGKLPEDQVQA 104
Query: 292 IMWQILDGVSYLHQNWILHRDLKPANIMVTVDGCVKIGDLGLARKF--NNMVQTLYTGDK 349
I Q++ + YLH + ILHRD+KP NI++ G +K+ D G AR N MV T G
Sbjct: 105 IAAQLVSALYYLHSHRILHRDMKPQNILLAKGGGIKLCDFGFARAMSTNTMVLTSIKG-- 162
Query: 350 VIVTIWYRAPELILGARHYTPAIDLWAVGCIFAEL-IGLRPIF 391
T Y +PEL+ R Y DLW+VGCI EL +G P +
Sbjct: 163 ---TPLYMSPELV-EERPYDHTADLWSVGCILYELAVGTPPFY 201
>CE23001 [R] KOG0589 Serine/threonine protein kinase
Length = 579
Score = 89.7 bits (221), Expect = 1e-17
Identities = 54/166 (32%), Positives = 92/166 (54%), Gaps = 7/166 (4%)
Query: 230 ACREMSLCRELDNNHLTKLVEIFLEKKSIYMVSEFAEHDLLQIIHFHSHPEKRLIPPRML 289
A E+SL +++ ++ + F E+ + + E+A+ L + + + L+ +
Sbjct: 215 ALNEVSLLSRIEHPNIIAYYDSFEEEGVLMIEMEYADGGTLAQMLSRT---QNLLDEEQI 271
Query: 290 KSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGCVKIGDLGLARKFNNMVQTLYTGDK 349
+M Q+ V+YLH+N +LHRDLK AN+ +T D VKIGD G+++ +TL G K
Sbjct: 272 GDMMIQMCSAVAYLHENSVLHRDLKTANVFLTRDSFVKIGDFGISKIMG--TETLAQGAK 329
Query: 350 VIV-TIWYRAPELILGARHYTPAIDLWAVGCIFAELIGLRPIFKGE 394
+V T +Y +PE+ G Y D+WA+GCI E+ L+ F+G+
Sbjct: 330 TVVGTPYYISPEMCSGV-SYNEKSDMWALGCILYEMCCLKKAFEGD 374
>Hs4503429 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 553
Score = 89.4 bits (220), Expect = 1e-17
Identities = 90/353 (25%), Positives = 144/353 (40%), Gaps = 76/353 (21%)
Query: 206 QFYAIKKFKTEREGVEHYTGISQSACREMSLCRELDNNHLT------KLVEIFLEKKSIY 259
Q+ A+K + E+ + A E+ + L T ++E F + +
Sbjct: 198 QYVALKMVRNEKR-------FHRQAAEEIRILEHLKKQDKTGSMNVIHMLESFTFRNHVC 250
Query: 260 MVSEFAEHDLLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIM 319
M E DL ++I + + ++++ IL + LH+N I+H DLKP NI+
Sbjct: 251 MAFELLSIDLYELIKKNKFQGFSV---QLVRKFAQSILQSLDALHKNKIIHCDLKPENIL 307
Query: 320 VTVDG--CVKIGDLGLARKFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAV 377
+ G K+ D G + F Q LYT I + +YRAPE+ILG+R+ TP ID+W+
Sbjct: 308 LKHHGRSSTKVIDFG-SSCFE--YQKLYT---YIQSRFYRAPEIILGSRYSTP-IDIWSF 360
Query: 378 GCIFAELIGLRPIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHKI---------WPN 428
CI AEL+ +P+F GE+ + +Q ++E++G P K+ + N
Sbjct: 361 RCILAELLTGQPLFPGED-----------EGDQLACMMELLGMPPPKLLEQSKRAKYFIN 409
Query: 429 IDSYPEYLQLAKMPKYRDNLTAWYQTAGGK-----------------DKTALDILYRLLQ 471
P Y + R L G K D ++ L R L
Sbjct: 410 SKGIPRYCSVTTQADGRVVLVGGRSRRGKKRGPPGSKDWGTALKGCDDYLFIEFLKRCLH 469
Query: 472 YDPIKRIDAIDALDHVYFTNGDPPVCENV--------------FEGLNYKYPP 510
+DP R+ AL H + + P + F+GL K PP
Sbjct: 470 WDPSARLTPAQALRHPWISKSVPRPLTTIDKVSGKRVVNPASAFQGLGSKLPP 522
>CE19302_1 [G] KOG0658 Glycogen synthase kinase-3
Length = 396
Score = 89.0 bits (219), Expect = 2e-17
Identities = 60/212 (28%), Positives = 105/212 (49%), Gaps = 25/212 (11%)
Query: 289 LKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVD-GCVKIGDLGLARKFNNMVQTLYTG 347
+K WQ+ +G+ YL + I+HRD+KP NI+V VD G +KI D G A+ +V +
Sbjct: 135 MKLYTWQLFEGIRYLQAHMIVHRDIKPVNILVDVDKGTLKIADFGSAK----VVLRGSSS 190
Query: 348 DKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELIGLRPIFKGEEAKMESKKSVLFQ 407
VT +YR PEL+L A+ Y +D+W+ GC E++ + +F G K+
Sbjct: 191 TSYQVTRFYRPPELLLDAKEYYWMVDVWSAGCCVGEMMKGKVLFPGASIKI--------- 241
Query: 408 ANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPKYRD--NLTAWYQTAGGKDKTALDI 465
+ I++ +G P + ++D Y++++ M + + + G +++ D
Sbjct: 242 --MLKLIVQAIGLPSAR---DLD----YMKVSSMIDQQSAVKVIGLKEVLGTENQEWADF 292
Query: 466 LYRLLQYDPIKRIDAIDALDHVYFTNGDPPVC 497
L +L+Y P +R+ L H +F P C
Sbjct: 293 LGAILRYRPRERLHGPKLLSHPFFDLIFTPKC 324
>7290841 [D] KOG0591 NIMA (never in mitosis)-related G2-specific
serine/threonine protein kinase
Length = 735
Score = 87.8 bits (216), Expect = 4e-17
Identities = 68/228 (29%), Positives = 110/228 (47%), Gaps = 24/228 (10%)
Query: 222 HYTGISQSAC----REMSLCRELDNNHLTKLVEIFL--EKKSIYMVSEF-AEHDLLQIIH 274
+Y + ++ C E+S+ R+L + ++ + + E KS+Y+V E A DL QI+
Sbjct: 51 NYDELDEAKCDALVSEISVLRQLQHPNIVQYYHHLVNREAKSVYIVMECCAGGDLAQIVQ 110
Query: 275 FHSHPEKRLIPPRMLKSIMWQILDGVSYLHQN----WILHRDLKPANIMVTVDGCVKIGD 330
+R P + + +++Q+ + H ILHRD+KPANI + G K+GD
Sbjct: 111 RARSQRQRFEEPYIWR-VLFQLCRALQVCHNKIPNGTILHRDIKPANIFLDAAGNAKLGD 169
Query: 331 LGLARKFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELIGLRPI 390
GLAR + + T Y +PEL+ G R Y D+WAVGC+ E+ LRP
Sbjct: 170 FGLARMLR---RDQSFAASFVGTPHYMSPELVKG-RKYDRKSDVWAVGCLVYEMCALRPP 225
Query: 391 FKGEE--------AKMESKKSVLFQANQFQKILEVMGSPDHKIWPNID 430
F+G A+ E + + Q+I+ M + DH+ P I+
Sbjct: 226 FRGRAFDQLSEKIAQGEFSRIPAIYSTDLQEIIAFMLAVDHEQRPGIE 273
>At3g08720 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 471
Score = 87.4 bits (215), Expect = 5e-17
Identities = 57/203 (28%), Positives = 104/203 (51%), Gaps = 16/203 (7%)
Query: 201 KPSQIQFYAIKKFKTEREGVEHYTGISQSACREMSLCRELDNNHLTKLVEIFLEKKSIYM 260
K + YA+K + ++ +++ ++ E + ++D+ + +L F K +Y+
Sbjct: 159 KKDTSEIYAMKVMRKDKIVEKNHAEYMKA---ERDILTKIDHPFIVQLKYSFQTKYRLYL 215
Query: 261 VSEFAE--HDLLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANI 318
V +F H Q+ H + L + + +I+ VS+LH+ I+HRDLKP NI
Sbjct: 216 VLDFINGGHLFFQLYH------QGLFREDLARVYTAEIVSAVSHLHEKGIMHRDLKPENI 269
Query: 319 MVTVDGCVKIGDLGLARKFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVG 378
++ VDG V + D GLA++F ++ + + T Y APE++ G H A D W+VG
Sbjct: 270 LMDVDGHVMLTDFGLAKEFEENTRS----NSMCGTTEYMAPEIVRGKGH-DKAADWWSVG 324
Query: 379 CIFAELIGLRPIFKGEEAKMESK 401
+ E++ +P F G + K++ K
Sbjct: 325 ILLYEMLTGKPPFLGSKGKIQQK 347
>ECU05g1510 [TDK] KOG0668 Casein kinase II alpha subunit
Length = 319
Score = 87.0 bits (214), Expect = 7e-17
Identities = 75/270 (27%), Positives = 132/270 (48%), Gaps = 39/270 (14%)
Query: 231 CREMSLCRELDNNHLTKLVEIFLEKKS-IY-MVSEFAEHDLLQIIHFHSHPEKRLIPPRM 288
CRE+ + R L + ++ KL+++ ++ +S IY ++ E+ EH+ I F K ++
Sbjct: 75 CREVLILRNLSHKNIIKLMDVVVDPESQIYSLIFEYIEHEDYAKI-FEKLCYKDIV---- 129
Query: 289 LKSIMWQILDGVSYLHQNWILHRDLKPANIMVT-VDGCVKIGDLGLARKFNNMVQTLYTG 347
QIL +SY H I+HRD+KP N+++ +KI D GLA ++ +
Sbjct: 130 --EYSRQILSALSYCHSMGIIHRDIKPQNMVINQARRELKIIDWGLAEFYHPKKEYSVR- 186
Query: 348 DKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELI-GLRPIFKGEEAKMESKKSVLF 406
+ + +Y+ PEL++ +Y ++D+W+ GC+ AEL+ RP F GE
Sbjct: 187 ---VASRYYKGPELLVDYPYYDYSLDIWSFGCVLAELVFKKRPFFHGES----------- 232
Query: 407 QANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKM-PKYR---DNLTAWYQTAGGKD--- 459
++Q KI ++G + ++ Y ++A + PKY + + T GK
Sbjct: 233 NSDQLVKIARILG------YTHLKKYVRKYKMAPLNPKYEGVGERVLLSSFTPPGKTGLY 286
Query: 460 KTALDILYRLLQYDPIKRIDAIDALDHVYF 489
A+D+L ++L YD R A + L H F
Sbjct: 287 TNAIDLLEKILIYDHQDRPTADECLRHPLF 316
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.317 0.134 0.397
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 35,698,900
Number of Sequences: 60738
Number of extensions: 1514832
Number of successful extensions: 8276
Number of sequences better than 1.0e-05: 1211
Number of HSP's better than 0.0 without gapping: 299
Number of HSP's successfully gapped in prelim test: 912
Number of HSP's that attempted gapping in prelim test: 5808
Number of HSP's gapped (non-prelim): 1816
length of query: 593
length of database: 30,389,216
effective HSP length: 112
effective length of query: 481
effective length of database: 23,586,560
effective search space: 11345135360
effective search space used: 11345135360
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)