ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIV3022 check: MH R KOG0594 General function prediction only Protein kinase PCTAIRE and related kinases
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIV3022 gi|2499590|sp|Q92241|PH85_KLULA NEGATIVE
REGULATOR OF THE PHO SYSTEM
(308 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YPL031c [R] KOG0594 Protein kinase PCTAIRE and related kinases 518 e-147
SPCC16C4.11 [R] KOG0594 Protein kinase PCTAIRE and related kinases 352 3e-97
Hs16936528 [R] KOG0594 Protein kinase PCTAIRE and related kinases 327 1e-89
Hs4557439 [R] KOG0594 Protein kinase PCTAIRE and related kinases 324 9e-89
Hs4826675 [UT] KOG0662 Cyclin-dependent kinase CDK5 317 1e-86
Hs5453860 [R] KOG0594 Protein kinase PCTAIRE and related kinases 310 1e-84
Hs15011928 [R] KOG0594 Protein kinase PCTAIRE and related kinases 310 1e-84
At3g48750 [R] KOG0594 Protein kinase PCTAIRE and related kinases 307 1e-83
CE21213 [UT] KOG0662 Cyclin-dependent kinase CDK5 306 2e-83
Hs16160923 [R] KOG0594 Protein kinase PCTAIRE and related kinases 304 9e-83
Hs4502709 [R] KOG0594 Protein kinase PCTAIRE and related kinases 303 2e-82
YBR160w [R] KOG0594 Protein kinase PCTAIRE and related kinases 303 3e-82
Hs4505649 [R] KOG0594 Protein kinase PCTAIRE and related kinases 303 3e-82
7303051 [UT] KOG0662 Cyclin-dependent kinase CDK5 301 1e-81
7292375 [R] KOG0594 Protein kinase PCTAIRE and related kinases 298 7e-81
SPBC11B10.09 [R] KOG0594 Protein kinase PCTAIRE and related kinases 293 2e-79
7297680 [R] KOG0594 Protein kinase PCTAIRE and related kinases 293 2e-79
CE00315 [R] KOG0594 Protein kinase PCTAIRE and related kinases 291 8e-79
7300650 [R] KOG0594 Protein kinase PCTAIRE and related kinases 286 3e-77
CE29073 [R] KOG0594 Protein kinase PCTAIRE and related kinases 284 1e-76
CE06779 [R] KOG0594 Protein kinase PCTAIRE and related kinases 284 1e-76
Hs6912584 [R] KOG0594 Protein kinase PCTAIRE and related kinases 282 5e-76
CE29612 [R] KOG0594 Protein kinase PCTAIRE and related kinases 277 2e-74
Hs21040235 [R] KOG0594 Protein kinase PCTAIRE and related kinases 276 2e-74
At2g38620 [R] KOG0594 Protein kinase PCTAIRE and related kinases 276 3e-74
At3g54180 [R] KOG0594 Protein kinase PCTAIRE and related kinases 265 6e-71
CE18009 [R] KOG0594 Protein kinase PCTAIRE and related kinases 259 3e-69
ECU08g1920 [R] KOG0594 Protein kinase PCTAIRE and related kinases 258 6e-69
Hs16936530 [R] KOG0594 Protein kinase PCTAIRE and related kinases 256 4e-68
CE26422 [D] KOG0600 Cdc2-related protein kinase 249 3e-66
At1g76540 [R] KOG0594 Protein kinase PCTAIRE and related kinases 248 8e-66
At1g20930 [R] KOG0594 Protein kinase PCTAIRE and related kinases 247 2e-65
Hs17452757 [UT] KOG0662 Cyclin-dependent kinase CDK5 246 2e-65
At1g67580 [R] KOG0663 Protein kinase PITSLRE and related kinases 236 4e-62
CE01761 [R] KOG0663 Protein kinase PITSLRE and related kinases 234 1e-61
SPBC18H10.15 [R] KOG0663 Protein kinase PITSLRE and related kinases 234 2e-61
At5g63370 [R] KOG0663 Protein kinase PITSLRE and related kinases 233 2e-61
Hs4502743 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymera... 230 2e-60
At5g10270 [D] KOG0600 Cdc2-related protein kinase 228 8e-60
7290565 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase... 225 7e-59
At5g64960 [D] KOG0600 Cdc2-related protein kinase 224 9e-59
SPAC2F3.15 [D] KOG0600 Cdc2-related protein kinase 224 1e-58
CE03811 [R] KOG0663 Protein kinase PITSLRE and related kinases 220 2e-57
7296346 [R] KOG0663 Protein kinase PITSLRE and related kinases 219 3e-57
Hs4502741 [R] KOG0594 Protein kinase PCTAIRE and related kinases 218 7e-57
At1g73690 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymera... 218 9e-57
YDL108w [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase... 218 1e-56
Hs16357496 [R] KOG0663 Protein kinase PITSLRE and related kinases 218 1e-56
Hs16332372 [R] KOG0663 Protein kinase PITSLRE and related kinases 218 1e-56
Hs16332370 [R] KOG0663 Protein kinase PITSLRE and related kinases 218 1e-56
Hs16332368 [R] KOG0663 Protein kinase PITSLRE and related kinases 218 1e-56
Hs16332366 [R] KOG0663 Protein kinase PITSLRE and related kinases 218 1e-56
Hs16332364 [R] KOG0663 Protein kinase PITSLRE and related kinases 218 1e-56
Hs16332362 [R] KOG0663 Protein kinase PITSLRE and related kinases 218 1e-56
Hs16332360 [R] KOG0663 Protein kinase PITSLRE and related kinases 218 1e-56
Hs16332358 [R] KOG0663 Protein kinase PITSLRE and related kinases 218 1e-56
Hs10835055 [R] KOG0663 Protein kinase PITSLRE and related kinases 218 1e-56
At1g66750 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymera... 217 1e-56
At1g18040 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymera... 216 4e-56
Hs16357498 [R] KOG0663 Protein kinase PITSLRE and related kinases 215 6e-56
Hs16357486 [R] KOG0663 Protein kinase PITSLRE and related kinases 215 6e-56
Hs16357484 [R] KOG0663 Protein kinase PITSLRE and related kinases 215 6e-56
Hs16357482 [R] KOG0663 Protein kinase PITSLRE and related kinases 215 6e-56
Hs16357480 [R] KOG0663 Protein kinase PITSLRE and related kinases 215 6e-56
7296451 [D] KOG0600 Cdc2-related protein kinase 214 1e-55
Hs16357494 [R] KOG0663 Protein kinase PITSLRE and related kinases 214 2e-55
Hs16357492 [R] KOG0663 Protein kinase PITSLRE and related kinases 214 2e-55
7291442 [D] KOG0669 Cyclin T-dependent kinase CDK9 213 2e-55
YGR040w [T] KOG0660 Mitogen-activated protein kinase 211 1e-54
Hs14110390 [D] KOG0600 Cdc2-related protein kinase 210 2e-54
Hs14110387 [D] KOG0600 Cdc2-related protein kinase 210 2e-54
Hs7706549 [D] KOG0600 Cdc2-related protein kinase 209 5e-54
Hs4502735 [R] KOG0594 Protein kinase PCTAIRE and related kinases 207 2e-53
Hs4502731 [R] KOG0663 Protein kinase PITSLRE and related kinases 207 2e-53
Hs16950647 [R] KOG0663 Protein kinase PITSLRE and related kinases 207 2e-53
Hs4502747 [D] KOG0669 Cyclin T-dependent kinase CDK9 206 3e-53
ECU08g0230 [R] KOG0594 Protein kinase PCTAIRE and related kinases 206 3e-53
SPBC19F8.07 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polyme... 202 4e-52
7302908 [R] KOG0594 Protein kinase PCTAIRE and related kinases 202 5e-52
YKL139w [D] KOG0600 Cdc2-related protein kinase 202 6e-52
7303804 [R] KOG0663 Protein kinase PITSLRE and related kinases 198 7e-51
SPBC32H8.10 [D] KOG0600 Cdc2-related protein kinase 197 2e-50
Hs4758652 [R] KOG0593 Predicted protein kinase KKIAMRE 196 5e-50
Hs4505569 [R] KOG0593 Predicted protein kinase KKIAMRE 195 8e-50
At5g39420 [D] KOG0600 Cdc2-related protein kinase 194 1e-49
At5g44290 [D] KOG0600 Cdc2-related protein kinase 193 2e-49
At5g50860 [D] KOG0600 Cdc2-related protein kinase 191 1e-48
SPAC23H4.17c [K] KOG0666 Cyclin C-dependent kinase CDK8 190 2e-48
Hs7662388 [T] KOG0661 MAPK related serine/threonine protein kinase 189 4e-48
At1g33770 [D] KOG0600 Cdc2-related protein kinase 189 6e-48
Hs16306492 [R] KOG0594 Protein kinase PCTAIRE and related kinases 188 7e-48
Hs11496279 [T] KOG0661 MAPK related serine/threonine protein kinase 188 7e-48
ECU02g1450 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymer... 188 7e-48
7297578 [T] KOG0661 MAPK related serine/threonine protein kinase 188 1e-47
YPR161c [D] KOG0600 Cdc2-related protein kinase 187 1e-47
CE26988 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase... 187 2e-47
At3g05050 [D] KOG0600 Cdc2-related protein kinase 187 2e-47
At1g53050 [D] KOG0600 Cdc2-related protein kinase 187 2e-47
At1g71530 [D] KOG0600 Cdc2-related protein kinase 186 4e-47
Hs7705551 [T] KOG0661 MAPK related serine/threonine protein kinase 186 5e-47
At1g03740 [D] KOG0600 Cdc2-related protein kinase 186 5e-47
At4g10010 [D] KOG0600 Cdc2-related protein kinase 185 8e-47
At1g09600 [D] KOG0600 Cdc2-related protein kinase 184 1e-46
At5g63610 [K] KOG0666 Cyclin C-dependent kinase CDK8 184 1e-46
At1g54610 [D] KOG0600 Cdc2-related protein kinase 184 1e-46
At1g10210 [T] KOG0660 Mitogen-activated protein kinase 184 2e-46
SPAC31G5.09c [T] KOG0660 Mitogen-activated protein kinase 183 3e-46
At4g22940 [D] KOG0600 Cdc2-related protein kinase 183 3e-46
At1g74330 [D] KOG0600 Cdc2-related protein kinase 183 3e-46
At1g59580 [T] KOG0660 Mitogen-activated protein kinase 183 3e-46
At2g18170 [T] KOG0660 Mitogen-activated protein kinase 182 5e-46
Hs20986501 [T] KOG0660 Mitogen-activated protein kinase 181 9e-46
Hs20986497 [T] KOG0660 Mitogen-activated protein kinase 181 9e-46
At1g18670 [D] KOG0600 Cdc2-related protein kinase 181 1e-45
7297009 [R] KOG0593 Predicted protein kinase KKIAMRE 181 1e-45
At4g13020 [T] KOG0661 MAPK related serine/threonine protein kinase 181 2e-45
Hs20986529 [T] KOG0660 Mitogen-activated protein kinase 180 3e-45
Hs20551615 [K] KOG0666 Cyclin C-dependent kinase CDK8 179 6e-45
7291043 [T] KOG0660 Mitogen-activated protein kinase 178 8e-45
Hs20986531 [T] KOG0660 Mitogen-activated protein kinase 178 1e-44
At4g36450 [T] KOG0660 Mitogen-activated protein kinase 178 1e-44
At2g43790 [T] KOG0660 Mitogen-activated protein kinase 178 1e-44
At1g57700 [D] KOG0600 Cdc2-related protein kinase 178 1e-44
7300773 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase... 178 1e-44
CE24971 [T] KOG0660 Mitogen-activated protein kinase 177 1e-44
CE18608 [R] KOG0594 Protein kinase PCTAIRE and related kinases 177 1e-44
CE01583 [T] KOG0660 Mitogen-activated protein kinase 177 1e-44
CE28918 [R] KOG0594 Protein kinase PCTAIRE and related kinases 177 2e-44
YBL016w [T] KOG0660 Mitogen-activated protein kinase 177 2e-44
CE20258 [R] KOG0593 Predicted protein kinase KKIAMRE 177 2e-44
7301110 [T] KOG0660 Mitogen-activated protein kinase 177 2e-44
At4g01370 [T] KOG0660 Mitogen-activated protein kinase 176 3e-44
SPAC24B11.06c [T] KOG0660 Mitogen-activated protein kinase 176 5e-44
Hs20562757 [T] KOG0660 Mitogen-activated protein kinase 176 5e-44
CE29478 [T] KOG0664 Nemo-like MAPK-related serine/threonine prot... 176 5e-44
CE29477 [T] KOG0664 Nemo-like MAPK-related serine/threonine prot... 176 5e-44
CE29476 [T] KOG0664 Nemo-like MAPK-related serine/threonine prot... 176 5e-44
Hs7106269 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymera... 175 6e-44
At3g59790 [T] KOG0660 Mitogen-activated protein kinase 175 6e-44
Hs4507281 [R] KOG0593 Predicted protein kinase KKIAMRE 175 8e-44
Hs7706059 [R] KOG0593 Predicted protein kinase KKIAMRE 174 1e-43
Hs4506785 [T] KOG0660 Mitogen-activated protein kinase 174 1e-43
CE12408 [T] KOG0661 MAPK related serine/threonine protein kinase 174 2e-43
Hs4502745 [K] KOG0666 Cyclin C-dependent kinase CDK8 173 3e-43
Hs17461944 [R] KOG0593 Predicted protein kinase KKIAMRE 173 3e-43
At2g46070 [T] KOG0660 Mitogen-activated protein kinase 172 4e-43
ECU08g1790 [D] KOG0600 Cdc2-related protein kinase 172 7e-43
CE23826 [D] KOG0669 Cyclin T-dependent kinase CDK9 172 7e-43
CE18824 [D] KOG0669 Cyclin T-dependent kinase CDK9 172 7e-43
7294866 [K] KOG0666 Cyclin C-dependent kinase CDK8 172 7e-43
At3g45640 [T] KOG0660 Mitogen-activated protein kinase 171 1e-42
Hs20986512 [T] KOG0660 Mitogen-activated protein kinase 169 4e-42
YLR113w [T] KOG0660 Mitogen-activated protein kinase 169 5e-42
At1g07880 [T] KOG0660 Mitogen-activated protein kinase 169 5e-42
7298087 [T] KOG0660 Mitogen-activated protein kinase 169 5e-42
Hs4506085 [T] KOG0660 Mitogen-activated protein kinase 168 1e-41
Hs7706445 [T] KOG0664 Nemo-like MAPK-related serine/threonine pr... 167 2e-41
Hs4506091 [T] KOG0660 Mitogen-activated protein kinase 167 2e-41
Hs20128774 [T] KOG0660 Mitogen-activated protein kinase 166 3e-41
At4g11330 [T] KOG0660 Mitogen-activated protein kinase 164 1e-40
CE11556 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase... 163 3e-40
CE06686 [T] KOG0660 Mitogen-activated protein kinase 163 3e-40
CE02602_1 [T] KOG0660 Mitogen-activated protein kinase 163 3e-40
SPBC8D2.01 [G] KOG0658 Glycogen synthase kinase-3 163 3e-40
ECU11g0960 [D] KOG0600 Cdc2-related protein kinase 162 7e-40
YPL042c [K] KOG0666 Cyclin C-dependent kinase CDK8 161 1e-39
Hs4503069 [T] KOG0660 Mitogen-activated protein kinase 161 1e-39
CE17815 [K] KOG0666 Cyclin C-dependent kinase CDK8 160 2e-39
At5g45430 [T] KOG0661 MAPK related serine/threonine protein kinase 160 2e-39
Hs4506089 [T] KOG0660 Mitogen-activated protein kinase 160 3e-39
At2g42880 [T] KOG0660 Mitogen-activated protein kinase 159 5e-39
At1g18150 [T] KOG0660 Mitogen-activated protein kinase 159 5e-39
CE29020 [T] KOG0660 Mitogen-activated protein kinase 159 6e-39
At3g18040 [T] KOG0660 Mitogen-activated protein kinase 158 1e-38
CE06762 [T] KOG0660 Mitogen-activated protein kinase 157 1e-38
SPBPI064 [G] KOG0658 Glycogen synthase kinase-3 157 2e-38
7295173 [T] KOG0664 Nemo-like MAPK-related serine/threonine prot... 157 2e-38
Hs7657498 [T] KOG0661 MAPK related serine/threonine protein kinase 156 4e-38
CE08727 [G] KOG0658 Glycogen synthase kinase-3 154 2e-37
At1g53510 [T] KOG0660 Mitogen-activated protein kinase 154 2e-37
At4g19110 [T] KOG0661 MAPK related serine/threonine protein kinase 153 3e-37
At3g14720 [T] KOG0660 Mitogen-activated protein kinase 153 3e-37
Hs20986516 [T] KOG0660 Mitogen-activated protein kinase 151 1e-36
At1g73670 [T] KOG0660 Mitogen-activated protein kinase 151 1e-36
CE29466 [T] KOG0665 Jun-N-terminal kinase (JNK) 150 2e-36
Hs21237745 [T] KOG0665 Jun-N-terminal kinase (JNK) 150 3e-36
Hs21237742 [T] KOG0665 Jun-N-terminal kinase (JNK) 150 3e-36
Hs20502986 [T] KOG0660 Mitogen-activated protein kinase 150 3e-36
At5g19010 [T] KOG0660 Mitogen-activated protein kinase 149 4e-36
At1g57870 [G] KOG0658 Glycogen synthase kinase-3 149 5e-36
Hs20986514 [T] KOG0660 Mitogen-activated protein kinase 149 7e-36
7290342 [G] KOG0658 Glycogen synthase kinase-3 149 7e-36
SPAC1687.15 [G] KOG0658 Glycogen synthase kinase-3 147 1e-35
SPBC119.08 [T] KOG0660 Mitogen-activated protein kinase 146 3e-35
At3g05840 [G] KOG0658 Glycogen synthase kinase-3 146 3e-35
CE21401 [G] KOG0658 Glycogen synthase kinase-3 146 4e-35
At5g26751 [G] KOG0658 Glycogen synthase kinase-3 145 6e-35
At2g01450 [T] KOG0660 Mitogen-activated protein kinase 145 6e-35
At1g09840 [G] KOG0658 Glycogen synthase kinase-3 145 6e-35
YMR139w [G] KOG0658 Glycogen synthase kinase-3 145 7e-35
Hs20986499 [T] KOG0660 Mitogen-activated protein kinase 145 7e-35
At1g06390 [G] KOG0658 Glycogen synthase kinase-3 145 7e-35
YHR030c [T] KOG0660 Mitogen-activated protein kinase 145 9e-35
CE17305 [T] KOG0665 Jun-N-terminal kinase (JNK) 145 9e-35
At4g18710 [G] KOG0658 Glycogen synthase kinase-3 145 9e-35
Hs22051130 [G] KOG0658 Glycogen synthase kinase-3 144 1e-34
Hs11995474 [G] KOG0658 Glycogen synthase kinase-3 144 1e-34
HsM4504163 [G] KOG0658 Glycogen synthase kinase-3 144 2e-34
HsM20070143 [T] KOG0665 Jun-N-terminal kinase (JNK) 144 2e-34
Hs21237739 [T] KOG0665 Jun-N-terminal kinase (JNK) 144 2e-34
Hs21237736 [T] KOG0665 Jun-N-terminal kinase (JNK) 144 2e-34
At2g30980 [G] KOG0658 Glycogen synthase kinase-3 144 2e-34
SPBC8D2.19 [T] KOG0661 MAPK related serine/threonine protein kinase 142 6e-34
ECU11g1290 [R] KOG0663 Protein kinase PITSLRE and related kinases 142 6e-34
At2g23080 [TDK] KOG0668 Casein kinase II alpha subunit 142 8e-34
CE27574 [T] KOG0665 Jun-N-terminal kinase (JNK) 141 1e-33
CE17062 [T] KOG0660 Mitogen-activated protein kinase 140 2e-33
Hs21361340 [G] KOG0658 Glycogen synthase kinase-3 140 2e-33
Hs4506081 [T] KOG0665 Jun-N-terminal kinase (JNK) 139 4e-33
Hs20986510 [T] KOG0665 Jun-N-terminal kinase (JNK) 139 4e-33
Hs20986506 [T] KOG0665 Jun-N-terminal kinase (JNK) 139 4e-33
At4g00720 [G] KOG0658 Glycogen synthase kinase-3 139 5e-33
YKL161c [T] KOG0660 Mitogen-activated protein kinase 137 2e-32
CE29318 [T] KOG0660 Mitogen-activated protein kinase 137 2e-32
At5g14640 [G] KOG0658 Glycogen synthase kinase-3 137 2e-32
At3g61160 [G] KOG0658 Glycogen synthase kinase-3 137 2e-32
7297631 [T] KOG0665 Jun-N-terminal kinase (JNK) 137 2e-32
SPAC23C11.11 [TDK] KOG0668 Casein kinase II alpha subunit 136 4e-32
Hs4503429 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 135 1e-31
YPR054w [T] KOG0660 Mitogen-activated protein kinase 134 2e-31
YJL141c [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 134 2e-31
Hs20986521 [T] KOG0665 Jun-N-terminal kinase (JNK) 134 2e-31
Hs20986519 [T] KOG0665 Jun-N-terminal kinase (JNK) 134 2e-31
Hs21361643 [T] KOG4717 Serine/threonine protein kinase 133 3e-31
Hs18552621 [R] KOG0597 Serine-threonine protein kinase FUSED 133 3e-31
ECU05g1510 [TDK] KOG0668 Casein kinase II alpha subunit 133 4e-31
CE05377 [G] KOG0658 Glycogen synthase kinase-3 133 4e-31
At3g50000 [TDK] KOG0668 Casein kinase II alpha subunit 132 5e-31
CE27220 [T] KOG0660 Mitogen-activated protein kinase 131 1e-30
Hs4503097 [TDK] KOG0668 Casein kinase II alpha subunit 131 1e-30
Hs4506095 [T] KOG0665 Jun-N-terminal kinase (JNK) 130 2e-30
Hs20986523 [T] KOG0665 Jun-N-terminal kinase (JNK) 130 2e-30
At5g67380 [TDK] KOG0668 Casein kinase II alpha subunit 130 3e-30
7298142 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 129 4e-30
SPAC3C7.06c [T] KOG0661 MAPK related serine/threonine protein ki... 129 5e-30
YIL035c [TDK] KOG0668 Casein kinase II alpha subunit 128 1e-29
Hs4503095 [TDK] KOG0668 Casein kinase II alpha subunit 127 2e-29
Hs5922004 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 127 2e-29
Hs4503427 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 127 2e-29
CE23751 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 127 2e-29
CE19878 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 127 2e-29
CE05897 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 127 2e-29
CE17321 [TDK] KOG0668 Casein kinase II alpha subunit 126 3e-29
CE18454 [T] KOG4717 Serine/threonine protein kinase 125 6e-29
At5g57630 [T] KOG0583 Serine/threonine protein kinase 125 6e-29
YDL079c [G] KOG0658 Glycogen synthase kinase-3 125 8e-29
CE20405 [G] KOG0658 Glycogen synthase kinase-3 125 8e-29
At2g23070 [TDK] KOG0668 Casein kinase II alpha subunit 124 1e-28
At3g61960 [OUT] KOG0595 Serine/threonine-protein kinase involved... 124 2e-28
7303211 [T] KOG4717 Serine/threonine protein kinase 124 2e-28
At2g30360 [T] KOG0583 Serine/threonine protein kinase 123 4e-28
SPAC1E11.03 [R] KOG0667 Dual-specificity tyrosine-phosphorylatio... 122 5e-28
7289745 [TDK] KOG0668 Casein kinase II alpha subunit 122 5e-28
Hs20550209 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 122 9e-28
SPCC18B5.11c [D] KOG0615 Serine/threonine protein kinase Chk2 an... 121 1e-27
YJL106w [T] KOG0661 MAPK related serine/threonine protein kinase 120 2e-27
Hs5922001 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 120 2e-27
HsM8923212 [T] KOG4717 Serine/threonine protein kinase 120 3e-27
At1g50230 [R] KOG0597 Serine-threonine protein kinase FUSED 119 4e-27
At3g13530 [T] KOG0198 MEKK and related serine/threonine protein ... 119 6e-27
YOR061w [TDK] KOG0668 Casein kinase II alpha subunit 119 7e-27
7298004 [G] KOG0658 Glycogen synthase kinase-3 119 7e-27
Hs21389587 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 118 9e-27
At1g53570 [T] KOG0198 MEKK and related serine/threonine protein ... 118 9e-27
YDR477w [T] KOG0583 Serine/threonine protein kinase 118 1e-26
At5g25110 [T] KOG0583 Serine/threonine protein kinase 118 1e-26
At4g29810 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 118 1e-26
Hs5921999 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 117 2e-26
ECU07g1270 [G] KOG0658 Glycogen synthase kinase-3 117 2e-26
At5g35980 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 117 2e-26
At3g07980 [T] KOG0198 MEKK and related serine/threonine protein ... 117 2e-26
SPAC2F7.03c [R] KOG0667 Dual-specificity tyrosine-phosphorylatio... 117 2e-26
At4g24740 [T] KOG0671 LAMMER dual specificity kinases 117 3e-26
7291976 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 117 3e-26
At5g01820 [T] KOG0583 Serine/threonine protein kinase 116 4e-26
At2g25090 [T] KOG0583 Serine/threonine protein kinase 116 5e-26
7299322 [R] KOG0611 Predicted serine/threonine protein kinase 115 6e-26
Hs20986508 [T] KOG0665 Jun-N-terminal kinase (JNK) 115 8e-26
CE23605 [T] KOG0665 Jun-N-terminal kinase (JNK) 115 8e-26
CE04172 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 115 8e-26
At5g39440 [T] KOG0583 Serine/threonine protein kinase 115 1e-25
At5g45810 [T] KOG0583 Serine/threonine protein kinase 114 1e-25
At5g35410 [T] KOG0583 Serine/threonine protein kinase 114 1e-25
CE19302_1 [G] KOG0658 Glycogen synthase kinase-3 114 1e-25
Hs7662210 [OUT] KOG0595 Serine/threonine-protein kinase involved... 114 2e-25
At4g18700 [T] KOG0583 Serine/threonine protein kinase 114 2e-25
At1g29230 [T] KOG0583 Serine/threonine protein kinase 114 2e-25
Hs22050308_2 [T] KOG0198 MEKK and related serine/threonine prote... 114 2e-25
YJL095w [T] KOG0198 MEKK and related serine/threonine protein ki... 114 2e-25
SPCC320.12c [D] KOG0580 Serine/threonine protein kinase 114 2e-25
SPAC9G1.02 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 an... 114 2e-25
Hs19424132 [D] KOG0591 NIMA (never in mitosis)-related G2-specif... 113 3e-25
CE04430 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 113 3e-25
At3g53570 [T] KOG0671 LAMMER dual specificity kinases 113 3e-25
Hs4502567_1 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase... 113 4e-25
At5g01810 [T] KOG0583 Serine/threonine protein kinase 112 5e-25
Hs18765758 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 112 7e-25
Hs18765756 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 112 7e-25
Hs18765754 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 112 7e-25
Hs18765752 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 112 7e-25
Hs18765750 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 112 7e-25
CE05866 [G] KOG0658 Glycogen synthase kinase-3 112 7e-25
CE05686 [A] KOG0670 U4/U6-associated splicing factor PRP4 112 7e-25
At3g06030 [T] KOG0198 MEKK and related serine/threonine protein ... 112 7e-25
At2g40120 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 112 7e-25
Hs4758222 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 112 9e-25
At4g32660 [T] KOG0671 LAMMER dual specificity kinases 111 1e-24
At3g08720 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 111 1e-24
YKL101w [D] KOG0588 Serine/threonine protein kinase 111 2e-24
At5g10930 [T] KOG0583 Serine/threonine protein kinase 111 2e-24
At1g30270 [T] KOG0583 Serine/threonine protein kinase 111 2e-24
7298926 [T] KOG0578 p21-activated serine/threonine protein kinase 111 2e-24
SPCC777.14 [A] KOG0670 U4/U6-associated splicing factor PRP4 110 2e-24
Hs13430860 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 110 2e-24
At3g08730 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 110 2e-24
7302464 [R] KOG0586 Serine/threonine protein kinase 110 3e-24
CE23001 [R] KOG0589 Serine/threonine protein kinase 110 3e-24
At1g54960 [T] KOG0198 MEKK and related serine/threonine protein ... 110 3e-24
At1g09000 [T] KOG0198 MEKK and related serine/threonine protein ... 110 3e-24
7304358 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 110 3e-24
YAR019c [T] KOG0198 MEKK and related serine/threonine protein ki... 109 4e-24
SPBC21.06c [T] KOG0198 MEKK and related serine/threonine protein... 109 4e-24
Hs5454096 [T] KOG0574 STE20-like serine/threonine kinase MST 109 4e-24
At2g37840 [OUT] KOG0595 Serine/threonine-protein kinase involved... 109 4e-24
Hs13569922 [R] KOG0611 Predicted serine/threonine protein kinase 109 6e-24
CE09532 [G] KOG0658 Glycogen synthase kinase-3 109 6e-24
CE01612 [G] KOG0658 Glycogen synthase kinase-3 109 6e-24
CE28643 [T] KOG0583 Serine/threonine protein kinase 108 7e-24
CE07458 [T] KOG0583 Serine/threonine protein kinase 108 7e-24
CE28218 [D] KOG0588 Serine/threonine protein kinase 108 1e-23
CE00847 [T] KOG0583 Serine/threonine protein kinase 108 1e-23
SPBC409.07c [T] KOG0581 Mitogen-activated protein kinase kinase ... 108 1e-23
SPAC1F3.02c [T] KOG0198 MEKK and related serine/threonine protei... 108 1e-23
HsM7657627 [D] KOG0575 Polo-like serine/threonine protein kinase 108 1e-23
Hs4507831 [OUT] KOG0595 Serine/threonine-protein kinase involved... 108 1e-23
Hs14770402 [R] KOG0586 Serine/threonine protein kinase 108 1e-23
Hs11386209 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 108 1e-23
At5g07070 [T] KOG0583 Serine/threonine protein kinase 107 2e-23
At4g24400 [T] KOG0583 Serine/threonine protein kinase 107 2e-23
YPL153c [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 107 2e-23
Hs4505601 [T] KOG0578 p21-activated serine/threonine protein kinase 107 2e-23
CE03232 [D] KOG0591 NIMA (never in mitosis)-related G2-specific ... 107 2e-23
YDL101c [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 107 3e-23
Hs4507275 [D] KOG0580 Serine/threonine protein kinase 107 3e-23
At2g34180 [T] KOG0583 Serine/threonine protein kinase 107 3e-23
7299160 [OUT] KOG0595 Serine/threonine-protein kinase involved i... 107 3e-23
SPCC74.03c [T] KOG0583 Serine/threonine protein kinase 106 4e-23
HsM4507279 [D] KOG0580 Serine/threonine protein kinase 106 4e-23
Hs21361433 [D] KOG0575 Polo-like serine/threonine protein kinase 106 4e-23
Hs19923468 [T] KOG4236 Serine/threonine protein kinase PKC mu/PK... 106 4e-23
Hs19923407 [D] KOG0591 NIMA (never in mitosis)-related G2-specif... 106 4e-23
7299437 [R] KOG0586 Serine/threonine protein kinase 106 4e-23
Hs21361133 [R] KOG0586 Serine/threonine protein kinase 106 5e-23
Hs17999535 [A] KOG0670 U4/U6-associated splicing factor PRP4 106 5e-23
Hs13899225 [R] KOG0586 Serine/threonine protein kinase 106 5e-23
CE28061 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 106 5e-23
CE28060 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 106 5e-23
CE28059 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 106 5e-23
CE28058 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 106 5e-23
CE28057 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 106 5e-23
CE28056 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 106 5e-23
CE28055 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 106 5e-23
CE28054 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 106 5e-23
CE28053 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 106 5e-23
CE28051 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 106 5e-23
CE24516 [OUT] KOG0595 Serine/threonine-protein kinase involved i... 106 5e-23
CE19219 [T] KOG0665 Jun-N-terminal kinase (JNK) 106 5e-23
YNL307c [G] KOG0658 Glycogen synthase kinase-3 105 6e-23
YDR507c [D] KOG0588 Serine/threonine protein kinase 105 6e-23
SPAC23H4.02 [T] KOG0583 Serine/threonine protein kinase 105 6e-23
HsM4505103 [R] KOG0586 Serine/threonine protein kinase 105 6e-23
CE19749 [T] KOG0665 Jun-N-terminal kinase (JNK) 105 6e-23
At5g66850 [T] KOG0198 MEKK and related serine/threonine protein ... 105 6e-23
At4g30960 [T] KOG0583 Serine/threonine protein kinase 105 6e-23
Hs7662170 [R] KOG0611 Predicted serine/threonine protein kinase 105 8e-23
Hs5174547 [T] KOG4279 Serine/threonine protein kinase 105 8e-23
Hs20545245 [D] KOG0588 Serine/threonine protein kinase 105 8e-23
CE09360 [Z] KOG0613 Projectin/twitchin and related proteins 105 8e-23
7291932 [A] KOG0670 U4/U6-associated splicing factor PRP4 105 8e-23
At5g45820 [T] KOG0583 Serine/threonine protein kinase 105 1e-22
At3g01090 [T] KOG0583 Serine/threonine protein kinase 105 1e-22
7299438 [R] KOG0586 Serine/threonine protein kinase 105 1e-22
7293496 [R] KOG0597 Serine-threonine protein kinase FUSED 105 1e-22
Hs4758128_2 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase... 105 1e-22
YNL298w [T] KOG0578 p21-activated serine/threonine protein kinase 104 1e-22
Hs14777335 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 104 1e-22
At3g17750 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 104 1e-22
At2g38490 [T] KOG0583 Serine/threonine protein kinase 104 1e-22
YCR073c [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and r... 104 2e-22
Hs9845489 [R] KOG0586 Serine/threonine protein kinase 104 2e-22
Hs9845487 [R] KOG0586 Serine/threonine protein kinase 104 2e-22
Hs4758702 [T] KOG4279 Serine/threonine protein kinase 104 2e-22
Hs22062450 [R] KOG0586 Serine/threonine protein kinase 104 2e-22
At1g51660 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 104 2e-22
7290150 [T] KOG0583 Serine/threonine protein kinase 104 2e-22
Hs7382496 [T] KOG0578 p21-activated serine/threonine protein kinase 103 2e-22
Hs5454094 [T] KOG0574 STE20-like serine/threonine kinase MST 103 2e-22
Hs4506075 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD... 103 2e-22
Hs16178962 [T] KOG0574 STE20-like serine/threonine kinase MST 103 2e-22
At5g58380 [T] KOG0583 Serine/threonine protein kinase 103 2e-22
At1g73460 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 103 2e-22
SPBC1604.14c [T] KOG0578 p21-activated serine/threonine protein ... 103 3e-22
CE20167 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD a... 103 3e-22
CE18967 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD a... 103 3e-22
CE06635 [Z] KOG0613 Projectin/twitchin and related proteins 103 3e-22
CE06634 [Z] KOG0613 Projectin/twitchin and related proteins 103 3e-22
At1g63700 [T] KOG0198 MEKK and related serine/threonine protein ... 103 3e-22
7294217 [D] KOG0588 Serine/threonine protein kinase 103 3e-22
Hs9966875 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 103 4e-22
Hs22057171 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 103 4e-22
7302570 [R] KOG0586 Serine/threonine protein kinase 103 4e-22
Hs4505373 [V] KOG1826 Ras GTPase activating protein RasGAP/neuro... 102 5e-22
At2g26980 [T] KOG0583 Serine/threonine protein kinase 102 5e-22
Hs4507273 [D] KOG0580 Serine/threonine protein kinase 102 7e-22
At3g21220 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 102 7e-22
7290249 [R] KOG0586 Serine/threonine protein kinase 102 7e-22
CE26793_1 [R] KOG0611 Predicted serine/threonine protein kinase 102 7e-22
YOL128c [G] KOG0658 Glycogen synthase kinase-3 102 9e-22
SPCC63.08c [OUT] KOG0595 Serine/threonine-protein kinase involve... 101 1e-21
Hs8923922 [R] KOG0586 Serine/threonine protein kinase 101 1e-21
Hs5031689 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD... 101 1e-21
CE27768 [R] KOG0586 Serine/threonine protein kinase 101 1e-21
CE23838 [R] KOG0586 Serine/threonine protein kinase 101 1e-21
At3g29160 [T] KOG0583 Serine/threonine protein kinase 101 2e-21
7290841 [D] KOG0591 NIMA (never in mitosis)-related G2-specific ... 100 2e-21
HsM4758524 [T] KOG0587 Traf2- and Nck-interacting kinase and rel... 100 3e-21
Hs7657335 [T] KOG0587 Traf2- and Nck-interacting kinase and rela... 100 3e-21
Hs22035606 [T] KOG0587 Traf2- and Nck-interacting kinase and rel... 100 3e-21
Hs22035604 [T] KOG0587 Traf2- and Nck-interacting kinase and rel... 100 3e-21
Hs22035602 [T] KOG0587 Traf2- and Nck-interacting kinase and rel... 100 3e-21
At1g13350 [A] KOG0670 U4/U6-associated splicing factor PRP4 100 3e-21
At1g49180_1 [OUT] KOG0595 Serine/threonine-protein kinase involv... 100 3e-21
Hs6031180 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and... 100 3e-21
Hs5803088 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and... 100 3e-21
Hs4505153 [T] KOG0198 MEKK and related serine/threonine protein ... 100 3e-21
At2g41860 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 100 3e-21
At1g01140 [T] KOG0583 Serine/threonine protein kinase 100 3e-21
YCL024w [T] KOG0583 Serine/threonine protein kinase 100 5e-21
SPBC1D7.05c [T] KOG0198 MEKK and related serine/threonine protei... 100 5e-21
CE06352 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 100 5e-21
At2g35890 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 100 5e-21
At1g08650 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 100 5e-21
SPAC57A10.02 [D] KOG0588 Serine/threonine protein kinase 99 6e-21
7301213 [R] KOG0589 Serine/threonine protein kinase 99 6e-21
Hs4502803 [D] KOG0590 Checkpoint kinase and related serine/threo... 99 8e-21
7300559 [T] KOG4279 Serine/threonine protein kinase 99 8e-21
Hs4502883_2 [T] KOG0671 LAMMER dual specificity kinases 99 8e-21
YHL007c [T] KOG0578 p21-activated serine/threonine protein kinase 99 1e-20
CE28251 [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 99 1e-20
At3g15220 [T] KOG0201 Serine/threonine protein kinase 99 1e-20
At2g31500 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 99 1e-20
YOL113w [T] KOG0578 p21-activated serine/threonine protein kinase 98 1e-20
YHR102w [T] KOG0201 Serine/threonine protein kinase 98 1e-20
HsM5729922 [T] KOG0198 MEKK and related serine/threonine protein... 98 1e-20
Hs20547806 [R] KOG0589 Serine/threonine protein kinase 98 1e-20
At3g53640 [A] KOG0670 U4/U6-associated splicing factor PRP4 98 1e-20
7293666 [D] KOG0575 Polo-like serine/threonine protein kinase 98 1e-20
YDL028c [D] KOG0596 Dual specificity; serine/threonine and tyros... 98 2e-20
Hs6005810 [T] KOG0576 Mitogen-activated protein kinase kinase ki... 98 2e-20
Hs5453966 [T] KOG0583 Serine/threonine protein kinase 98 2e-20
Hs14993776 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 98 2e-20
CE24761 [D] KOG0580 Serine/threonine protein kinase 98 2e-20
At3g04530 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 98 2e-20
YLR362w [T] KOG0198 MEKK and related serine/threonine protein ki... 97 2e-20
CE27670 [T] KOG0578 p21-activated serine/threonine protein kinase 97 2e-20
CE04173 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 97 2e-20
At5g60550 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase k... 97 2e-20
At3g25840 [A] KOG0670 U4/U6-associated splicing factor PRP4 97 2e-20
At1g69220 [T] KOG0576 Mitogen-activated protein kinase kinase ki... 97 2e-20
7298652 [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 97 2e-20
At4g12020_6 [T] KOG0198 MEKK and related serine/threonine protei... 97 2e-20
Hs5579478 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 97 3e-20
Hs4506737 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 97 3e-20
CE24993 [D] KOG0669 Cyclin T-dependent kinase CDK9 97 3e-20
At4g26070 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 97 3e-20
At3g18750 [R] KOG0584 Serine/threonine protein kinase 97 3e-20
At1g53165 [T] KOG0201 Serine/threonine protein kinase 97 3e-20
7291778 [T] KOG0579 Ste20-like serine/threonine protein kinase 97 3e-20
YBR028c [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 97 4e-20
Hs20479818 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 97 4e-20
Hs14728804 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 97 4e-20
ECU07g0360 [D] KOG0580 Serine/threonine protein kinase 97 4e-20
At4g14580 [T] KOG0583 Serine/threonine protein kinase 97 4e-20
At2g45490 [D] KOG0580 Serine/threonine protein kinase 97 4e-20
7300435 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and r... 97 4e-20
YPL209c [D] KOG0580 Serine/threonine protein kinase 96 5e-20
Hs7661994 [T] KOG0579 Ste20-like serine/threonine protein kinase 96 5e-20
At3g23000 [T] KOG0583 Serine/threonine protein kinase 96 5e-20
Hs21735556 [T] KOG0198 MEKK and related serine/threonine protein... 96 7e-20
CE27297 [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 96 7e-20
>YPL031c [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 305
Score = 518 bits (1335), Expect = e-147
Identities = 250/298 (83%), Positives = 273/298 (90%)
Query: 9 TRFKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPSTAIREISLMKELKHDN 68
++FKQLEK+GNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPSTAIREISLMKELKH+N
Sbjct: 5 SQFKQLEKLGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPSTAIREISLMKELKHEN 64
Query: 69 IVRLFDVIHTENKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGVAFC 128
IVRL+DVIHTENKLTLVFEFMDNDLKK+MD+R GN+ +GLE++LVKYFQWQLLQG+AFC
Sbjct: 65 IVRLYDVIHTENKLTLVFEFMDNDLKKYMDSRTVGNTPRGLELNLVKYFQWQLLQGLAFC 124
Query: 129 HENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGSR 188
HEN+ILHRDLKPQNLLIN RGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGSR
Sbjct: 125 HENKILHRDLKPQNLLINKRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGSR 184
Query: 189 NYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQLAKYNP 248
Y TSIDIWSCGCILAEMI GKPLFPG+NDEEQLKLIFD MGTP E WP VT+L KYNP
Sbjct: 185 TYSTSIDIWSCGCILAEMITGKPLFPGTNDEEQLKLIFDIMGTPNESLWPSVTKLPKYNP 244
Query: 249 LLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPWFAEYNH 306
+ PRDL+Q+LQ +T+E LD N++D LHGLLQLNPD RLSAK AL+HPWFAEY H
Sbjct: 245 NIQQRPPRDLRQVLQPHTKEPLDGNLMDFLHGLLQLNPDMRLSAKQALHHPWFAEYYH 302
>SPCC16C4.11 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 288
Score = 352 bits (904), Expect = 3e-97
Identities = 177/292 (60%), Positives = 220/292 (74%), Gaps = 10/292 (3%)
Query: 11 FKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPSTAIREISLMKELKHDNIV 70
+++LEK+G GTYA VYKG N+ TG VALK +++D++EGTPSTAIREISLMKEL+H NI+
Sbjct: 3 YQRLEKLGEGTYAHVYKGQNRVTGEIVALKVIRIDADEGTPSTAIREISLMKELRHPNIM 62
Query: 71 RLFDVIHTENKLTLVFEFMDNDLKKFMDNR-NKGNSHKGLEMDLVKYFQWQLLQGVAFCH 129
L DV+ TENKL LVFE+M+ DLKK+MD N+G L VK F QLL+G++FCH
Sbjct: 63 SLSDVLQTENKLMLVFEYMEKDLKKYMDTYGNQG----ALPPSQVKNFTQQLLKGISFCH 118
Query: 130 ENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGSRN 189
ENR+LHRDLKPQNLLIN+RG+LKL DFGLAR+ GIPVNTFS+EVVTLWYRAPDVL+GSR
Sbjct: 119 ENRVLHRDLKPQNLLINSRGELKLADFGLARSIGIPVNTFSNEVVTLWYRAPDVLLGSRV 178
Query: 190 YCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQLAKYNPL 249
Y TSIDIWS GCI+AEM G+PLF GSN+E+QL IF +GTP EQ+WP ++ L +Y P
Sbjct: 179 YSTSIDIWSVGCIMAEMATGRPLFAGSNNEDQLLKIFRLLGTPTEQSWPGISLLPEYKPT 238
Query: 250 LPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPWF 301
P + +DL L D +DLL +L+L P+ R + +DAL H WF
Sbjct: 239 FPIYKAQDLAYLF-----PTFDPLGLDLLRRMLRLQPELRTTGQDALQHAWF 285
>Hs16936528 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 298
Score = 327 bits (838), Expect = 1e-89
Identities = 163/294 (55%), Positives = 213/294 (72%), Gaps = 10/294 (3%)
Query: 11 FKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSE-EGTPSTAIREISLMKELKHDNI 69
F+++EK+G GTY VYK NK TG VALK+++LD+E EG PSTAIREISL+KEL H NI
Sbjct: 4 FQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNI 63
Query: 70 VRLFDVIHTENKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGVAFCH 129
V+L DVIHTENKL LVFEF+ DLKKFMD ++ G+ + L+K + +QLLQG+AFCH
Sbjct: 64 VKLLDVIHTENKLYLVFEFLHQDLKKFMD----ASALTGIPLPLIKSYLFQLLQGLAFCH 119
Query: 130 ENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGSRN 189
+R+LHRDLKPQNLLIN G +KL DFGLARAFG+PV T++ EVVTLWYRAP++L+G +
Sbjct: 120 SHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKY 179
Query: 190 YCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQLAKYNPL 249
Y T++DIWS GCI AEM+ + LFPG ++ +QL IF T+GTP E WP VT + Y P
Sbjct: 180 YSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPS 239
Query: 250 LPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPWFAE 303
P +D +++ LD++ LL +L +P+ R+SAK AL HP+F +
Sbjct: 240 FPKWARQDFSKVV-----PPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQD 288
>Hs4557439 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 305
Score = 324 bits (831), Expect = 9e-89
Identities = 163/293 (55%), Positives = 211/293 (71%), Gaps = 10/293 (3%)
Query: 11 FKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSE-EGTPSTAIREISLMKELKHDNI 69
F+++EK+G GTY VYK N+ TG VALK+++LD E EG PSTAIREISL+KELKH NI
Sbjct: 4 FQKVEKIGEGTYGVVYKAKNRETGQLVALKKIRLDLEMEGVPSTAIREISLLKELKHPNI 63
Query: 70 VRLFDVIHTENKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGVAFCH 129
VRL DV+H E KL LVFEF+ DLKK+MD+ L + L+K + +QLLQGV+FCH
Sbjct: 64 VRLLDVVHNERKLYLVFEFLSQDLKKYMDSTPGSE----LPLHLIKSYLFQLLQGVSFCH 119
Query: 130 ENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGSRN 189
+R++HRDLKPQNLLIN G +KL DFGLARAFG+P+ T++ EVVTLWYRAP++L+GS+
Sbjct: 120 SHRVIHRDLKPQNLLINELGAIKLADFGLARAFGVPLRTYTHEVVTLWYRAPEILLGSKF 179
Query: 190 YCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQLAKYNPL 249
Y T++DIWS GCI AEM+ K LFPG ++ +QL IF +GTP E TWP VTQL Y
Sbjct: 180 YTTAVDIWSIGCIFAEMVTRKALFPGDSEIDQLFRIFRMLGTPSEDTWPGVTQLPDYKGS 239
Query: 250 LPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPWFA 302
P + L++++ N L+ DLL LLQ +P R++AK AL HP+F+
Sbjct: 240 FPKWTRKGLEEIVPN-----LEPEGRDLLMQLLQYDPSQRITAKTALAHPYFS 287
>Hs4826675 [UT] KOG0662 Cyclin-dependent kinase CDK5
Length = 292
Score = 317 bits (813), Expect = 1e-86
Identities = 162/297 (54%), Positives = 212/297 (70%), Gaps = 12/297 (4%)
Query: 10 RFKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSE-EGTPSTAIREISLMKELKHDN 68
++++LEK+G GTY TV+K N+ T VALK V+LD + EG PS+A+REI L+KELKH N
Sbjct: 3 KYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKHKN 62
Query: 69 IVRLFDVIHTENKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGVAFC 128
IVRL DV+H++ KLTLVFEF D DLKK+ D+ N L+ ++VK F +QLL+G+ FC
Sbjct: 63 IVRLHDVLHSDKKLTLVFEFCDQDLKKYFDSCNGD-----LDPEIVKSFLFQLLKGLGFC 117
Query: 129 HENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGSR 188
H +LHRDLKPQNLLIN G+LKL DFGLARAFGIPV +S+EVVTLWYR PDVL G++
Sbjct: 118 HSRNVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAK 177
Query: 189 NYCTSIDIWSCGCILAEMI-MGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQLAKYN 247
Y TSID+WS GCI AE+ G+PLFPG++ ++QLK IF +GTP E+ WP +T+L Y
Sbjct: 178 LYSTSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQWPSMTKLPDYK 237
Query: 248 PLLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPWFAEY 304
P P P + N L+ DLL LL+ NP R+SA++AL HP+F+++
Sbjct: 238 PY--PMYPATTSLV---NVVPKLNATGRDLLQNLLKCNPVQRISAEEALQHPYFSDF 289
>Hs5453860 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 496
Score = 310 bits (795), Expect = 1e-84
Identities = 161/296 (54%), Positives = 208/296 (69%), Gaps = 10/296 (3%)
Query: 6 RYETRFKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPSTAIREISLMKELK 65
+ ET K L+K+G GTYATVYKG +K T VALKE++L+ EEG P TAIRE+SL+K+LK
Sbjct: 161 KLETYIK-LDKLGEGTYATVYKGKSKLTDNLVALKEIRLEHEEGAPCTAIREVSLLKDLK 219
Query: 66 HDNIVRLFDVIHTENKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGV 125
H NIV L D+IHTE LTLVFE++D DLK+++D+ GN + M VK F +QLL+G+
Sbjct: 220 HANIVTLHDIIHTEKSLTLVFEYLDKDLKQYLDDC--GNI---INMHNVKLFLFQLLRGL 274
Query: 126 AFCHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLM 185
A+CH ++LHRDLKPQNLLIN RG+LKL DFGLARA IP T+S+EVVTLWYR PD+L+
Sbjct: 275 AYCHRQKVLHRDLKPQNLLINERGELKLADFGLARAKSIPTKTYSNEVVTLWYRPPDILL 334
Query: 186 GSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQLAK 245
GS +Y T ID+W GCI EM G+PLFPGS EEQL IF +GTP E+TWP + +
Sbjct: 335 GSTDYSTQIDMWGVGCIFYEMATGRPLFPGSTVEEQLHFIFRILGTPTEETWPGILSNEE 394
Query: 246 YNPLLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPWF 301
+ + P+ + L ++ LD + DLL LLQ R+SA+DA+ HP+F
Sbjct: 395 FKTY---NYPKYRAEALLSHAPR-LDSDGADLLTKLLQFEGRNRISAEDAMKHPFF 446
>Hs15011928 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 448
Score = 310 bits (795), Expect = 1e-84
Identities = 161/296 (54%), Positives = 208/296 (69%), Gaps = 10/296 (3%)
Query: 6 RYETRFKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPSTAIREISLMKELK 65
+ ET K L+K+G GTYATVYKG +K T VALKE++L+ EEG P TAIRE+SL+K+LK
Sbjct: 113 KLETYIK-LDKLGEGTYATVYKGKSKLTDNLVALKEIRLEHEEGAPCTAIREVSLLKDLK 171
Query: 66 HDNIVRLFDVIHTENKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGV 125
H NIV L D+IHTE LTLVFE++D DLK+++D+ GN + M VK F +QLL+G+
Sbjct: 172 HANIVTLHDIIHTEKSLTLVFEYLDKDLKQYLDDC--GNI---INMHNVKLFLFQLLRGL 226
Query: 126 AFCHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLM 185
A+CH ++LHRDLKPQNLLIN RG+LKL DFGLARA IP T+S+EVVTLWYR PD+L+
Sbjct: 227 AYCHRQKVLHRDLKPQNLLINERGELKLADFGLARAKSIPTKTYSNEVVTLWYRPPDILL 286
Query: 186 GSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQLAK 245
GS +Y T ID+W GCI EM G+PLFPGS EEQL IF +GTP E+TWP + +
Sbjct: 287 GSTDYSTQIDMWGVGCIFYEMATGRPLFPGSTVEEQLHFIFRILGTPTEETWPGILSNEE 346
Query: 246 YNPLLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPWF 301
+ + P+ + L ++ LD + DLL LLQ R+SA+DA+ HP+F
Sbjct: 347 FKTY---NYPKYRAEALLSHAPR-LDSDGADLLTKLLQFEGRNRISAEDAMKHPFF 398
>At3g48750 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 294
Score = 307 bits (787), Expect = 1e-83
Identities = 154/296 (52%), Positives = 210/296 (70%), Gaps = 11/296 (3%)
Query: 10 RFKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSE-EGTPSTAIREISLMKELKHDN 68
+++++EK+G GTY VYK +K T +ALK+++L+ E EG PSTAIREISL+KE++H N
Sbjct: 3 QYEKVEKIGEGTYGVVYKARDKVTNETIALKKIRLEQEDEGVPSTAIREISLLKEMQHSN 62
Query: 69 IVRLFDVIHTENKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGVAFC 128
IV+ DV+H+E +L LVFE++D DLKK MD+ + ++ ++K + +Q+L+G+A+C
Sbjct: 63 IVKYDDVVHSEKRLYLVFEYLDLDLKKHMDSTPDFSK----DLHMIKTYLYQILRGIAYC 118
Query: 129 HENRILHRDLKPQNLLINNR-GQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGS 187
H +R+LHRDLKPQNLLI+ R LKL DFGLARAFGIPV TF+ EVVTLWYRAP++L+GS
Sbjct: 119 HSHRVLHRDLKPQNLLIDRRTNSLKLADFGLARAFGIPVRTFTHEVVTLWYRAPEILLGS 178
Query: 188 RNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQLAKYN 247
+Y T +DIWS GCI AEMI KPLFPG ++ +QL IF MGTP E TW VT L Y
Sbjct: 179 HHYSTPVDIWSVGCIFAEMISQKPLFPGDSEIDQLFKIFRIMGTPYEDTWRGVTSLPDYK 238
Query: 248 PLLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPWFAE 303
P P DL+ + N LD + VDLL +L ++P R++A+ AL H +F +
Sbjct: 239 SAFPKWKPTDLETFVPN-----LDPDGVDLLSKMLLMDPTKRINARAALEHEYFKD 289
>CE21213 [UT] KOG0662 Cyclin-dependent kinase CDK5
Length = 292
Score = 306 bits (785), Expect = 2e-83
Identities = 156/295 (52%), Positives = 203/295 (67%), Gaps = 12/295 (4%)
Query: 11 FKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSE-EGTPSTAIREISLMKELKHDNI 69
+ ++EK+G GTY TV+K NK +G VALK V+LD + EG PS+A+REI +++ELKH N+
Sbjct: 4 YDKMEKIGEGTYGTVFKARNKNSGEIVALKRVRLDDDDEGVPSSALREICILRELKHRNV 63
Query: 70 VRLFDVIHTENKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGVAFCH 129
VRL+DV+H+ENKLTLVFE+ D DLKKF D+ N ++ + QLL+G++FCH
Sbjct: 64 VRLYDVVHSENKLTLVFEYCDQDLKKFFDSLNGY-----MDAQTARSLMLQLLRGLSFCH 118
Query: 130 ENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGSRN 189
+ +LHRDLKPQNLLIN G LKL DFGLARAFG+PV FS+EVVTLWYR PDVL G++
Sbjct: 119 AHHVLHRDLKPQNLLINTNGTLKLADFGLARAFGVPVRCFSAEVVTLWYRPPDVLFGAKL 178
Query: 190 YCTSIDIWSCGCILAEMI-MGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQLAKYNP 248
Y TSID+WS GCI AE+ G+PLFPG++ ++QLK IF +G+P E WP +TQL Y P
Sbjct: 179 YNTSIDMWSAGCIFAEISNAGRPLFPGADVDDQLKRIFKQLGSPSEDNWPSITQLPDYKP 238
Query: 249 LLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPWFAE 303
H Q++ N L+ DLL LL NP R+ A AL H +FA+
Sbjct: 239 YPIYHPTLTWSQIVPN-----LNSRGRDLLQKLLVCNPAGRIDADAALRHAYFAD 288
>Hs16160923 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 472
Score = 304 bits (779), Expect = 9e-83
Identities = 157/292 (53%), Positives = 207/292 (70%), Gaps = 11/292 (3%)
Query: 11 FKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPSTAIREISLMKELKHDNIV 70
+ +L+K+G GTYATV+KG +K T VALKE++L+ EEG P TAIRE+SL+K LKH NIV
Sbjct: 142 YVKLDKLGEGTYATVFKGRSKLTENLVALKEIRLEHEEGAPCTAIREVSLLKNLKHANIV 201
Query: 71 RLFDVIHTENKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGVAFCHE 130
L D+IHT+ LTLVFE++D+DLK+++D+ GN + M VK F +QLL+G+A+CH
Sbjct: 202 TLHDLIHTDRSLTLVFEYLDSDLKQYLDHC--GNL---MSMHNVKIFMFQLLRGLAYCHH 256
Query: 131 NRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGSRNY 190
+ILHRDLKPQNLLIN RG+LKL DFGLARA +P T+S+EVVTLWYR PDVL+GS Y
Sbjct: 257 RKILHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTEY 316
Query: 191 CTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQLAKYNPL- 249
T ID+W GCI EM G+PLFPGS +E+L LIF +GTP E+TWP VT +++
Sbjct: 317 STPIDMWGVGCIHYEMATGRPLFPGSTVKEELHLIFRLLGTPTEETWPGVTAFSEFRTYS 376
Query: 250 LPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPWF 301
P ++P+ L N LD + + LL LL +R+SA+ AL+H +F
Sbjct: 377 FPCYLPQPL-----INHAPRLDTDGIHLLSSLLLYESKSRMSAEAALSHSYF 423
>Hs4502709 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 297
Score = 303 bits (776), Expect = 2e-82
Identities = 151/297 (50%), Positives = 208/297 (69%), Gaps = 9/297 (3%)
Query: 11 FKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSEE-GTPSTAIREISLMKELKHDNI 69
+ ++EK+G GTY VYKG +KTTG VA+K+++L+SEE G PSTAIREISL+KEL+H NI
Sbjct: 4 YTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPNI 63
Query: 70 VRLFDVIHTENKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGVAFCH 129
V L DV+ +++L L+FEF+ DLKK++D+ G ++ LVK + +Q+LQG+ FCH
Sbjct: 64 VSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQY---MDSSLVKSYLYQILQGIVFCH 120
Query: 130 ENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGSRN 189
R+LHRDLKPQNLLI+++G +KL DFGLARAFGIP+ ++ EVVTLWYR+P+VL+GS
Sbjct: 121 SRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEVVTLWYRSPEVLLGSAR 180
Query: 190 YCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQLAKYNPL 249
Y T +DIWS G I AE+ KPLF G ++ +QL IF +GTP + WP+V L Y
Sbjct: 181 YSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNT 240
Query: 250 LPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPWFAEYNH 306
P P L ++N LD+N +DLL +L +P R+S K ALNHP+F + ++
Sbjct: 241 FPKWKPGSLASHVKN-----LDENGLDLLSKMLIYDPAKRISGKMALNHPYFNDLDN 292
>YBR160w [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 298
Score = 303 bits (775), Expect = 3e-82
Identities = 157/298 (52%), Positives = 206/298 (68%), Gaps = 13/298 (4%)
Query: 11 FKQLEKVGNGTYATVYKGLNKTTGV---YVALKEVKLDSE-EGTPSTAIREISLMKELKH 66
+K+LEKVG GTY VYK L+ G VALK+++L+SE EG PSTAIREISL+KELK
Sbjct: 8 YKRLEKVGEGTYGVVYKALDLRPGQGQRVVALKKIRLESEDEGVPSTAIREISLLKELKD 67
Query: 67 DNIVRLFDVIHTE-NKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGV 125
DNIVRL+D++H++ +KL LVFEF+D DLK++M+ K L D+VK F QL +G+
Sbjct: 68 DNIVRLYDIVHSDAHKLYLVFEFLDLDLKRYMEGIPKDQP---LGADIVKKFMMQLCKGI 124
Query: 126 AFCHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLM 185
A+CH +RILHRDLKPQNLLIN G LKLGDFGLARAFG+P+ ++ E+VTLWYRAP+VL+
Sbjct: 125 AYCHSHRILHRDLKPQNLLINKDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVLL 184
Query: 186 GSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQLAK 245
G + Y T +D WS GCI AEM KP+F G ++ +Q+ IF +GTP E WP + L
Sbjct: 185 GGKQYSTGVDTWSIGCIFAEMCNRKPIFSGDSEIDQIFKIFRVLGTPNEAIWPDIVYLPD 244
Query: 246 YNPLLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPWFAE 303
+ P P +DL Q++ + LD +DLL LL +P R+SA+ A HP+F E
Sbjct: 245 FKPSFPQWRRKDLSQVVPS-----LDPRGIDLLDKLLAYDPINRISARRAAIHPYFQE 297
>Hs4505649 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 523
Score = 303 bits (775), Expect = 3e-82
Identities = 155/297 (52%), Positives = 206/297 (69%), Gaps = 12/297 (4%)
Query: 6 RYETRFKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPSTAIREISLMKELK 65
+ ET K LEK+G GTYATVYKG +K T VALKE++L+ EEG P TAIRE+SL+K+LK
Sbjct: 188 KMETYIK-LEKLGEGTYATVYKGRSKLTENLVALKEIRLEHEEGAPCTAIREVSLLKDLK 246
Query: 66 HDNIVRLFDVIHTENKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGV 125
H NIV L D++HT+ LTLVFE++D DLK++MD+ GN + M VK F +Q+L+G+
Sbjct: 247 HANIVTLHDIVHTDKSLTLVFEYLDKDLKQYMDDC--GNI---MSMHNVKLFLYQILRGL 301
Query: 126 AFCHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLM 185
A+CH ++LHRDLKPQNLLIN +G+LKL DFGLARA +P T+S+EVVTLWYR PDVL+
Sbjct: 302 AYCHRRKVLHRDLKPQNLLINEKGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLL 361
Query: 186 GSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQLAK 245
GS Y T ID+W GCI EM G+PLFPGS E++L LIF +GTP ++TWP ++ +
Sbjct: 362 GSSEYLTQIDMWGVGCIFFEMASGRPLFPGSTVEDELHLIFRLLGTPSQETWPGISSNEE 421
Query: 246 Y-NPLLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPWF 301
+ N P + P L N LD ++L+ LQ R+SA++A+ H +F
Sbjct: 422 FKNYNFPKYKPEPL-----INHAPRLDSEGIELIRKFLQYESKKRVSAEEAMKHVYF 473
>7303051 [UT] KOG0662 Cyclin-dependent kinase CDK5
Length = 294
Score = 301 bits (770), Expect = 1e-81
Identities = 160/298 (53%), Positives = 207/298 (68%), Gaps = 16/298 (5%)
Query: 10 RFKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSE-EGTPSTAIREISLMKELKHDN 68
++ ++EK+G GTY TV+KG N+ T VALK V+LD + EG PS+A+REI L+KELKH N
Sbjct: 3 KYDKMEKIGEGTYGTVFKGRNRDTMEIVALKRVRLDEDDEGVPSSALREICLLKELKHKN 62
Query: 69 IVRLFDVIHTENKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGVAFC 128
IVRL DV+H++ KLTLVFE D DLKK+ D+ N ++M + + F QLL+G+AFC
Sbjct: 63 IVRLIDVLHSDKKLTLVFEHCDQDLKKYFDSLNGE-----IDMAVCRSFMLQLLRGLAFC 117
Query: 129 HENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGSR 188
H + +LHRDLKPQNLLIN G+LKL DFGLARAFGIPV +S+EVVTLWYR PDVL G++
Sbjct: 118 HSHNVLHRDLKPQNLLINKNGELKLADFGLARAFGIPVKCYSAEVVTLWYRPPDVLFGAK 177
Query: 189 NYCTSIDIWSCGCILAEMI-MGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQLAKYN 247
Y TSID+WS GCILAE+ G+PLFPGS+ +QL IF +GTP E +WP V+ L+ Y
Sbjct: 178 LYTTSIDMWSAGCILAELADAGRPLFPGSDVLDQLMKIFRVLGTPNEDSWPGVSHLSDYV 237
Query: 248 PLLPPHMP--RDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPWFAE 303
L P P QL+ L+ DLL LL P+ R+SA+ A+ HP+F +
Sbjct: 238 AL--PSFPAITSWSQLVPR-----LNSKGRDLLQKLLICRPNQRISAEAAMQHPYFTD 288
>7292375 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 509
Score = 298 bits (763), Expect = 7e-81
Identities = 155/304 (50%), Positives = 201/304 (65%), Gaps = 11/304 (3%)
Query: 2 SPLLRYETRFKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPSTAIREISLM 61
SP + E K LE +G G+YATVYKG +K T VALKE++L EEG P TAIRE SL+
Sbjct: 184 SPFGKQEAYVK-LEPLGEGSYATVYKGFSKLTYQRVALKEIRLQEEEGAPFTAIREASLL 242
Query: 62 KELKHDNIVRLFDVIHTENKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQL 121
KELKH NIV L D++HT LT VFE+++ DL ++M+ G H+ V+ F +QL
Sbjct: 243 KELKHSNIVTLHDIVHTRETLTFVFEYVNTDLSQYMEKHPGGLDHRN-----VRLFLFQL 297
Query: 122 LQGVAFCHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAP 181
L+G+++CH+ R+LHRD+KPQNLLI++ G+LKL DFGLARA +P +T+S EVVTLWYR P
Sbjct: 298 LRGLSYCHKRRVLHRDVKPQNLLISDCGELKLADFGLARAKSVPSHTYSHEVVTLWYRPP 357
Query: 182 DVLMGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDE-EQLKLIFDTMGTPVEQTWPQV 240
DVL+GS Y TS+D+W GCI EM+ G P FPG D +QL IF +GTP E TWP V
Sbjct: 358 DVLLGSTEYSTSLDMWGVGCIFVEMVTGMPTFPGIRDTYDQLDKIFKLLGTPTEDTWPGV 417
Query: 241 TQLAKYNP-LLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHP 299
T Y P L + PR L + + + + +G LQLNP+ RL A DAL HP
Sbjct: 418 THFPGYKPHKLGFYRPRKLGHNFPRLYDIIEGETIA---NGFLQLNPEQRLGADDALQHP 474
Query: 300 WFAE 303
+FA+
Sbjct: 475 YFAQ 478
>SPBC11B10.09 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 297
Score = 293 bits (751), Expect = 2e-79
Identities = 147/300 (49%), Positives = 206/300 (68%), Gaps = 11/300 (3%)
Query: 11 FKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSE-EGTPSTAIREISLMKELKHDN- 68
++++EK+G GTY VYK +K +G VA+K+++L+ E EG PSTAIREISL+KE+ +N
Sbjct: 4 YQKVEKIGEGTYGVVYKARHKLSGRIVAMKKIRLEDESEGVPSTAIREISLLKEVNDENN 63
Query: 69 ---IVRLFDVIHTENKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGV 125
VRL D++H E+KL LVFEF+D DLKK+MD ++ + L+ LV+ F +QL+ GV
Sbjct: 64 RSNCVRLLDILHAESKLYLVFEFLDMDLKKYMDRISETGA-TSLDPRLVQKFTYQLVNGV 122
Query: 126 AFCHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLM 185
FCH RI+HRDLKPQNLLI+ G LKL DFGLAR+FG+P+ ++ E+VTLWYRAP+VL+
Sbjct: 123 NFCHSRRIIHRDLKPQNLLIDKEGNLKLADFGLARSFGVPLRNYTHEIVTLWYRAPEVLL 182
Query: 186 GSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQLAK 245
GSR+Y T +DIWS GCI AEMI PLFPG ++ +++ IF +GTP E+ WP VT L
Sbjct: 183 GSRHYSTGVDIWSVGCIFAEMIRRSPLFPGDSEIDEIFKIFQVLGTPNEEVWPGVTLLQD 242
Query: 246 YNPLLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPWFAEYN 305
Y P DL +++ N E+ ++LL +L +P R+SAK AL + +++
Sbjct: 243 YKSTFPRWKRMDLHKVVPNGEED-----AIELLSAMLVYDPAHRISAKRALQQNYLRDFH 297
>7297680 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 297
Score = 293 bits (751), Expect = 2e-79
Identities = 148/292 (50%), Positives = 198/292 (67%), Gaps = 9/292 (3%)
Query: 11 FKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSE-EGTPSTAIREISLMKELKHDNI 69
F+++EK+G GTY VYKG N+ TG VA+K+++L+S+ EG PSTAIREISL+KELKH+NI
Sbjct: 4 FEKIEKIGEGTYGVVYKGRNRLTGQIVAMKKIRLESDDEGVPSTAIREISLLKELKHENI 63
Query: 70 VRLFDVIHTENKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGVAFCH 129
V L DV+ EN++ L+FEF+ DLKK+MD+ K +E +LV+ + +Q+ + FCH
Sbjct: 64 VCLEDVLMEENRIYLIFEFLSMDLKKYMDSLPVD---KHMESELVRSYLYQITSAILFCH 120
Query: 130 ENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGSRN 189
R+LHRDLKPQNLLI+ G +K+ DFGL R+FGIPV ++ E+VTLWYRAP+VL+GS
Sbjct: 121 RRRVLHRDLKPQNLLIDKSGLIKVADFGLGRSFGIPVRIYTHEIVTLWYRAPEVLLGSPR 180
Query: 190 YCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQLAKYNPL 249
Y +DIWS GCI AEM KPLF G ++ +QL +F + TP E WP VT L Y
Sbjct: 181 YSCPVDIWSIGCIFAEMATRKPLFQGDSEIDQLFRMFRILKTPTEDIWPGVTSLPDYKNT 240
Query: 250 LPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPWF 301
P L L+N LD N +DL+ +L +P R+SAKD L HP+F
Sbjct: 241 FPCWSTNQLTNQLKN-----LDANGIDLIQKMLIYDPVHRISAKDILEHPYF 287
>CE00315 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 332
Score = 291 bits (745), Expect = 8e-79
Identities = 145/294 (49%), Positives = 196/294 (66%), Gaps = 6/294 (2%)
Query: 11 FKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSE-EGTPSTAIREISLMKELKHDNI 69
F +LEK+G GTY VYKG N+ T VA+K+++L+SE EG PSTA+REISL+KEL+H N+
Sbjct: 22 FTKLEKIGEGTYGVVYKGKNRRTNAMVAMKKIRLESEDEGVPSTAVREISLLKELQHPNV 81
Query: 70 VRLFDVIHTENKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGVAFCH 129
V L VI EN+L L+FEF+ DLK++MD K L ++ +K + +Q+LQ + FCH
Sbjct: 82 VGLEAVIMQENRLFLIFEFLSFDLKRYMDQLGKDEY---LPLETLKSYTFQILQAMCFCH 138
Query: 130 ENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGSRN 189
+ R++HRDLKPQNLL++N G +KL DFGLARA GIP+ ++ EVVTLWYRAP++LMG++
Sbjct: 139 QRRVIHRDLKPQNLLVDNNGAIKLADFGLARAIGIPIRVYTHEVVTLWYRAPEILMGAQR 198
Query: 190 YCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQLAKYNPL 249
Y +D+WS GCI AEM KPLF G ++ ++L IF +GTP E W V L Y
Sbjct: 199 YSMGVDMWSIGCIFAEMATKKPLFQGDSEIDELFRIFRVLGTPTELEWNGVESLPDYKAT 258
Query: 250 LPPHMPRDLKQLL--QNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPWF 301
P L+ + + +LDD LL GLL +P RL+AK AL HP+F
Sbjct: 259 FPKWRENFLRDKFYDKKTGKHLLDDTAFSLLEGLLIYDPSLRLNAKKALVHPYF 312
>7300650 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 314
Score = 286 bits (732), Expect = 3e-77
Identities = 142/299 (47%), Positives = 200/299 (66%), Gaps = 13/299 (4%)
Query: 11 FKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSE-EGTPSTAIREISLMKELKHDNI 69
F++ EK+G GTY VYK + +TG VALK+++L+ E EG PSTAIREISL+K LKH N+
Sbjct: 8 FQRAEKIGEGTYGIVYKARSNSTGQDVALKKIRLEGETEGVPSTAIREISLLKNLKHPNV 67
Query: 70 VRLFDVIHTENKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGVAFCH 129
V+LFDV+ + N L ++FE+++ DLKK MD + + + L+K + Q+L V FCH
Sbjct: 68 VQLFDVVISGNNLYMIFEYLNMDLKKLMDKKKDVFTPQ-----LIKSYMHQILDAVGFCH 122
Query: 130 ENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGSRN 189
NRILHRDLKPQNLL++ G++KL DFGLARAF +P+ ++ EVVTLWYRAP++L+G++
Sbjct: 123 TNRILHRDLKPQNLLVDTAGKIKLADFGLARAFNVPMRAYTHEVVTLWYRAPEILLGTKF 182
Query: 190 YCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQLAKYNPL 249
Y T +DIWS GCI +EMIM + LFPG ++ +QL IF T+ TP E WP VTQL +
Sbjct: 183 YSTGVDIWSLGCIFSEMIMRRSLFPGDSEIDQLYRIFRTLSTPDETNWPGVTQLPDFKTK 242
Query: 250 LPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPWFAEYNHAN 308
P ++ Q + + +L+ +L +P+ R+SAKDAL H +F H +
Sbjct: 243 FPRWEGTNMPQ-------PITEHEAHELIMSMLCYDPNLRISAKDALQHAYFRNVQHVD 294
>CE29073 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 700
Score = 284 bits (727), Expect = 1e-76
Identities = 142/292 (48%), Positives = 201/292 (68%), Gaps = 13/292 (4%)
Query: 11 FKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPSTAIREISLMKELKHDNIV 70
+++L+K+G GTYATV++G + T +VALKE++L+ EEG P TAIRE+SL++ L+H N+V
Sbjct: 361 YEKLDKLGEGTYATVFRGRSILTNKFVALKEIRLEQEEGAPCTAIREVSLLRNLRHANVV 420
Query: 71 RLFDVIHTENKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGVAFCHE 130
L D+IHT+ LTLVFE++D DLK++MD+ N ++M+ ++ F +QLL+G+A+CH+
Sbjct: 421 TLHDIIHTDRLLTLVFEYVDRDLKQYMDSCNNA-----MQMNNIRLFLYQLLRGLAYCHQ 475
Query: 131 NRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGSRNY 190
R+LHRDLKPQNLLI +G+LKL DFGLARA +P T+S+EVVTLWYR PDVL+GS +Y
Sbjct: 476 RRVLHRDLKPQNLLITAKGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTDY 535
Query: 191 CTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQLAKYNPLL 250
T ID+W GCIL EMI G+ LFPG EQL LIF T+G+P P + + + P
Sbjct: 536 STHIDMWGVGCILFEMIAGRALFPGGTPTEQLGLIFRTLGSPRPDRHPTICEKPTFYPYA 595
Query: 251 PPHMPRD--LKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPW 300
H D +Q+ + +D + +LL LQ R+SA +A+ HP+
Sbjct: 596 NRHYNPDPLCRQIPR------IDAHGFELLMKFLQYEGKDRVSAAEAVKHPF 641
>CE06779 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 577
Score = 284 bits (727), Expect = 1e-76
Identities = 142/292 (48%), Positives = 201/292 (68%), Gaps = 13/292 (4%)
Query: 11 FKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPSTAIREISLMKELKHDNIV 70
+++L+K+G GTYATV++G + T +VALKE++L+ EEG P TAIRE+SL++ L+H N+V
Sbjct: 238 YEKLDKLGEGTYATVFRGRSILTNKFVALKEIRLEQEEGAPCTAIREVSLLRNLRHANVV 297
Query: 71 RLFDVIHTENKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGVAFCHE 130
L D+IHT+ LTLVFE++D DLK++MD+ N ++M+ ++ F +QLL+G+A+CH+
Sbjct: 298 TLHDIIHTDRLLTLVFEYVDRDLKQYMDSCNNA-----MQMNNIRLFLYQLLRGLAYCHQ 352
Query: 131 NRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGSRNY 190
R+LHRDLKPQNLLI +G+LKL DFGLARA +P T+S+EVVTLWYR PDVL+GS +Y
Sbjct: 353 RRVLHRDLKPQNLLITAKGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTDY 412
Query: 191 CTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQLAKYNPLL 250
T ID+W GCIL EMI G+ LFPG EQL LIF T+G+P P + + + P
Sbjct: 413 STHIDMWGVGCILFEMIAGRALFPGGTPTEQLGLIFRTLGSPRPDRHPTICEKPTFYPYA 472
Query: 251 PPHMPRD--LKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPW 300
H D +Q+ + +D + +LL LQ R+SA +A+ HP+
Sbjct: 473 NRHYNPDPLCRQIPR------IDAHGFELLMKFLQYEGKDRVSAAEAVKHPF 518
>Hs6912584 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 451
Score = 282 bits (721), Expect = 5e-76
Identities = 155/304 (50%), Positives = 205/304 (66%), Gaps = 10/304 (3%)
Query: 2 SPLLRYETRFKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPSTAIREISLM 61
SP +++LEK+G G+YATVYKG +K G VALK ++L EEGTP TAIRE SL+
Sbjct: 108 SPKFGKADSYEKLEKLGEGSYATVYKGKSKVNGKLVALKVIRLQEEEGTPFTAIREASLL 167
Query: 62 KELKHDNIVRLFDVIHTENKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQL 121
K LKH NIV L D+IHT+ LTLVFE++ DL ++MD ++ G GL D VK F +QL
Sbjct: 168 KGLKHANIVLLHDIIHTKETLTLVFEYVHTDLCQYMD-KHPG----GLHPDNVKLFLFQL 222
Query: 122 LQGVAFCHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAP 181
L+G+++ H+ ILHRDLKPQNLLI++ G+LKL DFGLARA +P +T+S+EVVTLWYR P
Sbjct: 223 LRGLSYIHQRYILHRDLKPQNLLISDTGELKLADFGLARAKSVPSHTYSNEVVTLWYRPP 282
Query: 182 DVLMGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSND-EEQLKLIFDTMGTPVEQTWPQV 240
DVL+GS Y T +D+W GCI EMI G FPG D ++QL+ IF +GTP E TWP V
Sbjct: 283 DVLLGSTEYSTCLDMWGVGCIFVEMIQGVAAFPGMKDIQDQLERIFLVLGTPNEDTWPGV 342
Query: 241 TQLAKYNP-LLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHP 299
L + P + ++L+Q N V ++ DL LLQ +P RLSA+ AL+H
Sbjct: 343 HSLPHFKPERFTLYSSKNLRQ-AWNKLSYV--NHAEDLASKLLQCSPKNRLSAQAALSHE 399
Query: 300 WFAE 303
+F++
Sbjct: 400 YFSD 403
>CE29612 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 426
Score = 277 bits (708), Expect = 2e-74
Identities = 147/300 (49%), Positives = 197/300 (65%), Gaps = 12/300 (4%)
Query: 11 FKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPSTAIREISLMKELKHDNIV 70
+K+++K+G G+YATVYK +K G VALKE+KL +EG P TAIRE SL++ L+H NIV
Sbjct: 108 YKRIDKLGEGSYATVYKCESKLDGSIVALKEIKLQFQEGLPFTAIREASLLRNLRHANIV 167
Query: 71 RLFDVIHTENKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGVAFCHE 130
L D+ + ++LT VFE+M DL K+++ + GL+ +K +QLL+G+ FCH
Sbjct: 168 SLHDIFYQHHQLTFVFEYMKMDLSKYLEQ-----NVYGLDSIDIKLLLFQLLRGLDFCHR 222
Query: 131 NRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGSRNY 190
+ILHRDLKPQNLL++ G LKL DFGLARA +P T+S EVVTLWYR PDVLMGS +Y
Sbjct: 223 KKILHRDLKPQNLLLDEDGVLKLADFGLARAKSVPSRTYSHEVVTLWYRPPDVLMGSTDY 282
Query: 191 CTSIDIWSCGCILAEMIMGKPLFPGSND------EEQLKLIFDTMGTPVEQTWPQVTQLA 244
TS+D+W GCI AE+ G LFPGS D ++QL +IF GTP E+ WP+V L
Sbjct: 283 STSLDMWGVGCIFAEICTGAALFPGSKDSHYPGTKDQLDMIFSIRGTPDEKKWPEVKTLP 342
Query: 245 KYNPLLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPWFAEY 304
Y P L P R+L + N + +LL LLQL P++R+SA A+ HP+FA +
Sbjct: 343 GYTPELFPRY-RELSFIAVNPMFTKILKTGQELLGMLLQLRPESRVSAASAMLHPYFASF 401
>Hs21040235 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 384
Score = 276 bits (707), Expect = 2e-74
Identities = 149/294 (50%), Positives = 198/294 (66%), Gaps = 10/294 (3%)
Query: 11 FKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPSTAIREISLMKELKHDNIV 70
+ LEK+G G+YATVYKG+++ G VALK + +++EEG P TAIRE SL+K LKH NIV
Sbjct: 52 YLNLEKLGEGSYATVYKGISRINGQLVALKVISMNAEEGVPFTAIREASLLKGLKHANIV 111
Query: 71 RLFDVIHTENKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGVAFCHE 130
L D+IHT+ LT VFE+M DL ++M +++ G GL V+ F +QLL+G+A+ H
Sbjct: 112 LLHDIIHTKETLTFVFEYMHTDLAQYM-SQHPG----GLHPHNVRLFMFQLLRGLAYIHH 166
Query: 131 NRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGSRNY 190
+LHRDLKPQNLLI++ G+LKL DFGLARA IP T+SSEVVTLWYR PD L+G+ Y
Sbjct: 167 QHVLHRDLKPQNLLISHLGELKLADFGLARAKSIPSQTYSSEVVTLWYRPPDALLGATEY 226
Query: 191 CTSIDIWSCGCILAEMIMGKPLFPG-SNDEEQLKLIFDTMGTPVEQTWPQVTQLAKYNP- 248
+ +DIW GCI EM G+PLFPG SN EQL+ I++ +G P E TWP V++L YNP
Sbjct: 227 SSELDIWGAGCIFIEMFQGQPLFPGVSNILEQLEKIWEVLGVPTEDTWPGVSKLPNYNPE 286
Query: 249 LLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPWFA 302
P PR L ++ N V DL +L+ P R+SA++AL H +F+
Sbjct: 287 WFPLPTPRSL-HVVWNRLGRV--PEAEDLASQMLKGFPRDRVSAQEALVHDYFS 337
>At2g38620 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 311
Score = 276 bits (706), Expect = 3e-74
Identities = 148/307 (48%), Positives = 207/307 (67%), Gaps = 21/307 (6%)
Query: 10 RFKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLD-SEEGTPSTAIREISLMKELKHD- 67
++++LEKVG GTY VYK + KTTG VALK+ +L+ EEG P TA+REISL++ L
Sbjct: 3 KYEKLEKVGEGTYGKVYKAMEKTTGKLVALKKTRLEMDEEGIPPTALREISLLQMLSQSI 62
Query: 68 NIVRLFDVIHT------------ENKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVK 115
IVRL V H ++ L LVFE++D DLKKF+D+ KG++ + LE LV+
Sbjct: 63 YIVRLLCVEHVIQSKDSTVSHSPKSNLYLVFEYLDTDLKKFIDSHRKGSNPRPLEASLVQ 122
Query: 116 YFQWQLLQGVAFCHENRILHRDLKPQNLLIN-NRGQLKLGDFGLARAFGIPVNTFSSEVV 174
F +QL +GVA CH + +LHRDLKPQNLL++ ++G LK+ D GL+RAF +P+ ++ E+V
Sbjct: 123 RFMFQLFKGVAHCHSHGVLHRDLKPQNLLLDKDKGILKIADLGLSRAFTVPLKAYTHEIV 182
Query: 175 TLWYRAPDVLMGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVE 234
TLWYRAP+VL+GS +Y T++DIWS GCI AEMI + LFPG ++ +QL IF +GTP E
Sbjct: 183 TLWYRAPEVLLGSTHYSTAVDIWSVGCIFAEMIRRQALFPGDSEFQQLLHIFRLLGTPTE 242
Query: 235 QTWPQVTQLAKYNPLLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKD 294
Q WP V L ++ + P P+DL + + + L +DLL +L+ NP R+SAK
Sbjct: 243 QQWPGVMALRDWH-VYPKWEPQDLSRAVPS-----LSPEGIDLLTQMLKYNPAERISAKA 296
Query: 295 ALNHPWF 301
AL+HP+F
Sbjct: 297 ALDHPYF 303
>At3g54180 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 309
Score = 265 bits (677), Expect = 6e-71
Identities = 144/305 (47%), Positives = 202/305 (66%), Gaps = 19/305 (6%)
Query: 10 RFKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLD-SEEGTPSTAIREISLMKELKHD- 67
++++LEKVG GTY VYK + K TG VALK+ +L+ EEG P TA+REISL++ L
Sbjct: 3 KYEKLEKVGEGTYGKVYKAMEKGTGKLVALKKTRLEMDEEGIPPTALREISLLQMLSTSI 62
Query: 68 NIVRLFDVIH----------TENKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYF 117
+VRL V H T++ L LVFE++D DLKKF+D+ KG + K LE L++
Sbjct: 63 YVVRLLCVEHVHQPSTKSQSTKSNLYLVFEYLDTDLKKFIDSYRKGPNPKPLEPFLIQKL 122
Query: 118 QWQLLQGVAFCHENRILHRDLKPQNLL-INNRGQLKLGDFGLARAFGIPVNTFSSEVVTL 176
+QL +GVA CH + +LHRDLKPQNLL + ++ LK+ D GL RAF +P+ +++ E+VTL
Sbjct: 123 MFQLCKGVAHCHSHGVLHRDLKPQNLLLVKDKELLKIADLGLGRAFTVPLKSYTHEIVTL 182
Query: 177 WYRAPDVLMGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQT 236
WYRAP+VL+GS +Y T +D+WS GCI AEM+ + LFPG ++ +QL IF +GTP EQ
Sbjct: 183 WYRAPEVLLGSTHYSTGVDMWSVGCIFAEMVRRQALFPGDSEFQQLLHIFRLLGTPTEQQ 242
Query: 237 WPQVTQLAKYNPLLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDAL 296
WP V+ L ++ + P P+DL + + L VDLL +L+ NP R+SAK AL
Sbjct: 243 WPGVSTLRDWH-VYPKWEPQDLTLAVPS-----LSPQGVDLLTKMLKYNPAERISAKTAL 296
Query: 297 NHPWF 301
+HP+F
Sbjct: 297 DHPYF 301
>CE18009 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 384
Score = 259 bits (662), Expect = 3e-69
Identities = 137/320 (42%), Positives = 199/320 (61%), Gaps = 23/320 (7%)
Query: 1 MSPLLRYETRFKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLD-SEEGTPSTAIREIS 59
++P + RF L ++G GTY V+K ++ V ALK ++ D EEG PST +REIS
Sbjct: 35 IAPERDLQGRFCSLRRIGEGTYGVVFKAIHVRDNVKCALKMIRTDRDEEGIPSTCLREIS 94
Query: 60 LMKELKHDNIVRLFDVIH----------------TENKLTLVFEFMDNDLKKFMDNRNKG 103
+K+L+HDNIV LFD+I+ + +KL +VFEF+D DLK ++
Sbjct: 95 CIKDLQHDNIVTLFDIIYASHFLNYNNIFFEKFSSNSKLYMVFEFIDRDLKNLLEMLEPT 154
Query: 104 NSHKGLEMDLVKYFQWQLLQGVAFCHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFG 163
NS L + VK F WQLL +++CH RI+HRDLKPQN+L+++ G +K+ DFGLAR F
Sbjct: 155 NSV--LPPNYVKSFMWQLLSALSYCHLRRIVHRDLKPQNILVSDSGVIKIADFGLARNFS 212
Query: 164 IPVNTFSSEVVTLWYRAPDVLMGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLK 223
P ++ EVVTLWYR P++L+GS+ Y TS+D+WS GCI +E+ KPLFPG + QL
Sbjct: 213 FPSRNYTHEVVTLWYRPPEILLGSQRYSTSLDMWSLGCIFSEIASNKPLFPGECEISQLF 272
Query: 224 LIFDTMGTPVEQTWPQVTQLAKYNPLLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQ 283
IF+ +GTP ++WP V Y + P P +LK+L + + L N +D+L +L+
Sbjct: 273 KIFEIVGTPNIKSWPGVDSFPHYKAVF-PQWPVNLKKLEETS---CLTGNGLDVLREILR 328
Query: 284 LNPDARLSAKDALNHPWFAE 303
P+ RL+AK AL+H +F +
Sbjct: 329 YPPERRLTAKGALSHRYFLQ 348
>ECU08g1920 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 296
Score = 258 bits (660), Expect = 6e-69
Identities = 126/292 (43%), Positives = 189/292 (64%), Gaps = 9/292 (3%)
Query: 11 FKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSE-EGTPSTAIREISLMKELKHDNI 69
F++LEK+G GTY VYK + T VALK+++L++E EG P+T IREI L+K LKH I
Sbjct: 5 FQKLEKIGEGTYGVVYKARERNTNRVVALKKIRLENENEGIPATTIREILLLKNLKHSTI 64
Query: 70 VRLFDVIHTENKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGVAFCH 129
V L DVI+ NK+ LVFE+++ DL++++D + + + +E V+ QLL + +CH
Sbjct: 65 VELSDVIYNNNKMYLVFEYVELDLRRYLDRMS--DEGRLVEEGFVRKMSQQLLTAMEYCH 122
Query: 130 ENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGSRN 189
I HRDLKPQN+L++ + +KL DFGL RA GIP+ T+++EVVTLWYR P++L+G +
Sbjct: 123 SRNIFHRDLKPQNILVDPKENIKLADFGLGRAAGIPLRTYTTEVVTLWYRPPELLLGCKY 182
Query: 190 YCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQLAKYNPL 249
Y S+D+WS CI+AE+++ +P FPG ++ +QL IF +GTP W V Y
Sbjct: 183 YDASVDVWSAACIMAEVVLMRPFFPGDSEIDQLFRIFKVLGTPNNSRWSNVENFPNYKVE 242
Query: 250 LPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPWF 301
P P DLK + + D + VDL+ +L+ +P R++AK+ L+H +F
Sbjct: 243 FPVWDPVDLKTIFRG------DPDFVDLISKMLEYDPKMRMTAKNGLSHKYF 288
>Hs16936530 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 264
Score = 256 bits (653), Expect = 4e-68
Identities = 141/294 (47%), Positives = 183/294 (61%), Gaps = 44/294 (14%)
Query: 11 FKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSE-EGTPSTAIREISLMKELKHDNI 69
F+++EK+G GTY VYK NK TG VALK+++LD+E EG PSTAIREISL+KEL H NI
Sbjct: 4 FQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNI 63
Query: 70 VRLFDVIHTENKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGVAFCH 129
V+L DVIHTENKL LVFEF+ DLKKFMD ++ G+ + L+K + +QLLQG+AFCH
Sbjct: 64 VKLLDVIHTENKLYLVFEFLHQDLKKFMD----ASALTGIPLPLIKSYLFQLLQGLAFCH 119
Query: 130 ENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGSRN 189
+R+LHRDLKPQNLLIN G +KL DFGLARAFG+PV T++ EV
Sbjct: 120 SHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVTR-------------- 165
Query: 190 YCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQLAKYNPL 249
+ LFPG ++ +QL IF T+GTP E WP VT + Y P
Sbjct: 166 --------------------RALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPS 205
Query: 250 LPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPWFAE 303
P +D +++ LD++ LL +L +P R+SAK AL HP+F +
Sbjct: 206 FPKWARQDFSKVV-----PPLDEDGRSLLSQMLHYDPYKRISAKAALAHPFFQD 254
>CE26422 [D] KOG0600 Cdc2-related protein kinase
Length = 684
Score = 249 bits (637), Expect = 3e-66
Identities = 127/309 (41%), Positives = 189/309 (61%), Gaps = 18/309 (5%)
Query: 9 TRFKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSE-EGTPSTAIREISLMKELKHD 67
T + L+++G GTY VYK +N TG VALK V+L++E EG P TAIREI ++++L H
Sbjct: 309 THYTMLDQIGEGTYGQVYKAVNNLTGEQVALKRVRLENEKEGFPITAIREIKILRQLHHK 368
Query: 68 NIVRLFDVI----------HTENKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYF 117
NIVRL D++ T LVFE++D+DL ++++ + +K L K
Sbjct: 369 NIVRLMDIVIDDISMDELKRTRANFYLVFEYVDHDLIGLLESKELVDFNKDQICSLFK-- 426
Query: 118 QWQLLQGVAFCHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLW 177
QLL+G+A+ H LHRD+K N+L+NN+G+LK+ D GLAR + +++ V+TLW
Sbjct: 427 --QLLEGLAYIHNTGFLHRDIKCSNILVNNKGELKIADLGLARLWEKESRLYTNRVITLW 484
Query: 178 YRAPDVLMGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTW 237
YR P++L+G Y +ID+WS GC+L E+ KPLF G+N+ QL+LI G+P W
Sbjct: 485 YRPPELLLGDERYGPAIDVWSTGCMLGELFTRKPLFNGNNEFGQLELISKVCGSPNVDNW 544
Query: 238 PQVTQLAKYNPLLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALN 297
P++T+L +N M R ++ ++ E ++ VDLL +L LNP+ R+SAK+ALN
Sbjct: 545 PELTELVGWNTF---RMKRTYQRRIREEFEHIMPREAVDLLDKMLTLNPEKRISAKEALN 601
Query: 298 HPWFAEYNH 306
HPW H
Sbjct: 602 HPWIRSLEH 610
>At1g76540 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 313
Score = 248 bits (633), Expect = 8e-66
Identities = 136/299 (45%), Positives = 196/299 (65%), Gaps = 16/299 (5%)
Query: 11 FKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKL-DSEEGTPSTAIREISLMKELKHD-N 68
F++LEKVG GTY VY+ K TG VALK+ +L + EEG PST +REIS+++ L D +
Sbjct: 14 FEKLEKVGEGTYGKVYRAREKATGKIVALKKTRLHEDEEGVPSTTLREISILRMLARDPH 73
Query: 69 IVRLFDV---IHTENK--LTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQ 123
+VRL DV + E K L LVFE+MD D+KKF+ R+ ++ K + +K +QL +
Sbjct: 74 VVRLMDVKQGLSKEGKTVLYLVFEYMDTDVKKFI--RSFRSTGKNIPTQTIKSLMYQLCK 131
Query: 124 GVAFCHENRILHRDLKPQNLLINNRG-QLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPD 182
G+AFCH + ILHRDLKP NLL++ + +LK+ D GLARAF +P+ ++ E++TLWYRAP+
Sbjct: 132 GMAFCHGHGILHRDLKPHNLLMDPKTMRLKIADLGLARAFTLPMKKYTHEILTLWYRAPE 191
Query: 183 VLMGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQ 242
VL+G+ +Y T++D+WS GCI AE++ + +F G ++ +QL IF GTP E+ WP V+
Sbjct: 192 VLLGATHYSTAVDMWSVGCIFAELVTNQAIFQGDSELQQLLHIFKLFGTPNEEMWPGVST 251
Query: 243 LAKYNPLLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPWF 301
L ++ P P L + N LD+ VDLL +LQ P R+SAK A+ HP+F
Sbjct: 252 LKNWHE-YPQWKPSTLSSAVPN-----LDEAGVDLLSKMLQYEPAKRISAKMAMEHPYF 304
>At1g20930 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 315
Score = 247 bits (630), Expect = 2e-65
Identities = 134/309 (43%), Positives = 198/309 (63%), Gaps = 16/309 (5%)
Query: 1 MSPLLRYETRFKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKL-DSEEGTPSTAIREIS 59
+ P + F++LEKVG GTY VY+ K TG+ VALK+ +L + EEG P T +REIS
Sbjct: 6 VKPAVSAMEAFEKLEKVGEGTYGKVYRAREKATGMIVALKKTRLHEDEEGVPPTTLREIS 65
Query: 60 LMKELKHD-NIVRLFDVIHTENK-----LTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDL 113
+++ L D +IVRL DV NK L LVFE++D DLKKF+ R+ + + + +
Sbjct: 66 ILRMLARDPHIVRLMDVKQGINKEGKTVLYLVFEYVDTDLKKFI--RSFRQAGQNIPQNT 123
Query: 114 VKYFQWQLLQGVAFCHENRILHRDLKPQNLLINNRGQ-LKLGDFGLARAFGIPVNTFSSE 172
VK +QL +G+AFCH + +LHRDLKP NLL++ + LK+ D GLARAF +P+ ++ E
Sbjct: 124 VKCLMYQLCKGMAFCHGHGVLHRDLKPHNLLMDRKTMTLKIADLGLARAFTLPMKKYTHE 183
Query: 173 VVTLWYRAPDVLMGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTP 232
++TLWYRAP+VL+G+ +Y T +D+WS GCI AE++ + +F G ++ +QL IF +GTP
Sbjct: 184 ILTLWYRAPEVLLGATHYSTGVDMWSVGCIFAELVTKQAIFAGDSELQQLLRIFRLLGTP 243
Query: 233 VEQTWPQVTQLAKYNPLLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSA 292
E+ WP V++L ++ P P L + N LD+ +DLL +L+ P R+SA
Sbjct: 244 NEEVWPGVSKLKDWHE-YPQWKPLSLSTAVPN-----LDEAGLDLLSKMLEYEPAKRISA 297
Query: 293 KDALNHPWF 301
K A+ HP+F
Sbjct: 298 KKAMEHPYF 306
>Hs17452757 [UT] KOG0662 Cyclin-dependent kinase CDK5
Length = 366
Score = 246 bits (629), Expect = 2e-65
Identities = 141/305 (46%), Positives = 192/305 (62%), Gaps = 26/305 (8%)
Query: 2 SPLLRYETRFKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLD-SEEGTPSTAIREISL 60
S +L E K+LEK+G GTY TV+K N T VALK V+LD +++G PS+A+REI L
Sbjct: 66 SNILSREDEQKKLEKIGEGTYGTVFKAKNWETHEIVALKWVRLDDNDDGVPSSALREICL 125
Query: 61 MKELKHDNIVRLFDVIHTENKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQ 120
+KELKH NIVRL D++H++ KLTLVF+F LKK+ D+ N L+ ++VK F +Q
Sbjct: 126 LKELKHKNIVRLHDLLHSDKKLTLVFKFCHQHLKKYFDSCNGD-----LDPEIVKSFLFQ 180
Query: 121 LLQGVAFCHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRA 180
LL+G+ FCH +L RDLKPQNLLIN G+LKL DFGL+RAFGIP+
Sbjct: 181 LLKGLGFCHSRNVLRRDLKPQNLLINRNGELKLADFGLSRAFGIPICY------------ 228
Query: 181 PDVLMGSRNYCTSIDIWSCGCILAEMI-MGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQ 239
V G++ Y TSID+WS GCI AE+ G PLFPG++ ++QLK IF +G ++ WP
Sbjct: 229 --VFFGAKLYSTSIDLWSAGCIFAELANAGWPLFPGNDVDDQLKRIFWLLGMLTKEQWPS 286
Query: 240 VTQLAKYNPLLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHP 299
+T+L Y L P P + N L DLL LL+ NP +SA++AL +P
Sbjct: 287 MTKLPDYK--LYPLYPATTSLV---NIVPKLSATGRDLLQNLLKCNPCQCISAEEALQYP 341
Query: 300 WFAEY 304
+F+++
Sbjct: 342 YFSDF 346
>At1g67580 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 752
Score = 236 bits (601), Expect = 4e-62
Identities = 125/299 (41%), Positives = 186/299 (61%), Gaps = 11/299 (3%)
Query: 11 FKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSE-EGTPSTAIREISLMKELKHDNI 69
F++L K+ GTY VY+ +K TG VALK+VK++ E EG P T++REI+++ H +I
Sbjct: 406 FERLNKIDEGTYGVVYRAKDKKTGEIVALKKVKMEKEREGFPLTSLREINILLSFHHPSI 465
Query: 70 VRLFDVI--HTENKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGVAF 127
V + +V+ + + + +V E+M++DLK M+ + S VK QLL+GV +
Sbjct: 466 VDVKEVVVGSSLDSIFMVMEYMEHDLKALMETMKQRFSQSE-----VKCLMLQLLEGVKY 520
Query: 128 CHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGS 187
H+N +LHRDLK NLL+NNRG+LK+ DFGLAR +G P+ ++ VVTLWYRAP++L+G+
Sbjct: 521 LHDNWVLHRDLKTSNLLLNNRGELKICDFGLARQYGSPLKPYTHLVVTLWYRAPELLLGA 580
Query: 188 RNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQLAKYN 247
+ Y T+ID+WS GCI+AE++M PLF G + +QL IF +GTP E WP ++L
Sbjct: 581 KQYSTAIDMWSLGCIMAELLMKAPLFNGKTEFDQLDKIFRILGTPNESIWPGFSKLPGVK 640
Query: 248 PLLPPHMPRDLKQLLQNNT---EEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPWFAE 303
H L++ + VL D DLL+ LL +P+ R++ +AL H WF E
Sbjct: 641 VNFVKHQYNLLRKKFPATSFTGAPVLSDAGFDLLNKLLTYDPERRITVNEALKHDWFRE 699
>CE01761 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 719
Score = 234 bits (597), Expect = 1e-61
Identities = 131/299 (43%), Positives = 188/299 (62%), Gaps = 11/299 (3%)
Query: 11 FKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSE-EGTPSTAIREIS-LMKELKHDN 68
++ + +V GT+ VY+G +K T VALK +K++ E EG P TA+REI+ L+K H N
Sbjct: 356 YECVNRVDEGTFGVVYRGKDKRTDEIVALKRLKMEKEKEGFPITALREINMLLKAGNHPN 415
Query: 69 IVRLFDVIHTEN--KLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGVA 126
IV + +++ N K+ + EF+++D+K +D ++ N K + K QLL G+
Sbjct: 416 IVNVKEILLGSNMDKIYMAMEFVEHDMKSLLDTMSRRN--KRFSIGEQKTLLQQLLSGIE 473
Query: 127 FCHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMG 186
H+ ILHRDLK NLL++++G LK+ DFGLAR +G P+ F+S VVTLWYR+P++L+G
Sbjct: 474 HMHKLWILHRDLKTSNLLMSHKGILKIADFGLAREYGDPLKKFTSIVVTLWYRSPELLLG 533
Query: 187 SRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQLAKY 246
+R Y T +D+WS GCI+AE I+ KPLFPG + EQ+K IF MGTP E WP VT+L +
Sbjct: 534 TRLYSTPVDMWSVGCIMAEFILLKPLFPGRGELEQIKKIFMEMGTPTESIWPGVTELDGW 593
Query: 247 NPLLPPHMPRD--LKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPWFAE 303
L P + K+ L +L+D LL+GLL L+P R SA AL+H WF E
Sbjct: 594 KALTFEKYPYNQLRKRFLAG---RLLNDTGFKLLNGLLTLDPKNRFSATQALDHEWFTE 649
>SPBC18H10.15 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 398
Score = 234 bits (596), Expect = 2e-61
Identities = 131/296 (44%), Positives = 179/296 (60%), Gaps = 11/296 (3%)
Query: 11 FKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSEE-GTPSTAIREISLMKELKHDNI 69
++ LEK+ G+Y VY+GL+K+T VALK++K D G P T++REI + ++HDNI
Sbjct: 74 YEILEKIEEGSYGIVYRGLDKSTNTLVALKKIKFDPNGIGFPITSLREIESLSSIRHDNI 133
Query: 70 VRLFDVIHTEN--KLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGVAF 127
V L V+ ++ + LV EFM++DLK +DN + VK QLL AF
Sbjct: 134 VELEKVVVGKDLKDVYLVMEFMEHDLKTLLDNMPED-----FLQSEVKTLMLQLLAATAF 188
Query: 128 CHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGS 187
H + LHRDLKP NLL+NN G++KL DFGLAR P ++ + VVTLWYRAP++L+G+
Sbjct: 189 MHHHWYLHRDLKPSNLLMNNTGEIKLADFGLARPVSEPKSSLTRLVVTLWYRAPELLLGA 248
Query: 188 RNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQLAKYN 247
+Y ID+WS GCI AEMI PLF G ++ +QL IF+ +G P + WPQ L N
Sbjct: 249 PSYGKEIDMWSIGCIFAEMITRTPLFSGKSELDQLYKIFNLLGYPTREEWPQYFLLPYAN 308
Query: 248 PLLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPWFAE 303
+ P +P K + L N DLL+ LL LNP R+SAK+AL HP+F E
Sbjct: 309 KIKHPTVPTHSK---IRTSIPNLTGNAYDLLNRLLSLNPAKRISAKEALEHPYFYE 361
>At5g63370 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 612
Score = 233 bits (595), Expect = 2e-61
Identities = 124/310 (40%), Positives = 189/310 (60%), Gaps = 18/310 (5%)
Query: 6 RYETRFKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKL-----DSEEGTPSTAIREISL 60
R F++L K+ GTY VYK ++ T VALK++K+ + E G P T++REI++
Sbjct: 292 RSVNEFQKLNKINEGTYGIVYKARDEKTKEIVALKKIKMKEDRFEEEYGFPLTSLREINI 351
Query: 61 MKELKHDNIVRLFDVI---HTENKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYF 117
+ H IV + +V+ +N + +V E +++DL+ MD R + S VK
Sbjct: 352 LLSCNHPAIVNVKEVVVGGKNDNDVYMVMEHLEHDLRGVMDRRKEPFSTSE-----VKCL 406
Query: 118 QWQLLQGVAFCHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLW 177
QLL G+ + H N I+HRDLKP NLL+NN G+LK+ DFG+AR +G P+ ++ V+T W
Sbjct: 407 MMQLLDGLKYLHTNWIIHRDLKPSNLLMNNCGELKICDFGMARQYGSPIKPYTQMVITQW 466
Query: 178 YRAPDVLMGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTW 237
YR P++L+G++ Y T++D+WS GCI+AE++ KPLFPG ++ +QL+ IF +GTP E W
Sbjct: 467 YRPPELLLGAKEYSTAVDMWSVGCIMAELLSQKPLFPGKSELDQLQKIFAVLGTPNEAIW 526
Query: 238 PQVTQL----AKYNPLLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAK 293
P + AK+ P P +M R + ++L + DLL+ LL L+P+ RL+ +
Sbjct: 527 PGFSSFPNAKAKF-PTQPYNMLRKKFPAISFVGGQILSERGFDLLNSLLTLDPEKRLTVE 585
Query: 294 DALNHPWFAE 303
DALNH WF E
Sbjct: 586 DALNHGWFHE 595
>Hs4502743 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 346
Score = 230 bits (587), Expect = 2e-60
Identities = 119/297 (40%), Positives = 185/297 (62%), Gaps = 15/297 (5%)
Query: 10 RFKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKL----DSEEGTPSTAIREISLMKELK 65
R+++L+ +G G +ATVYK +K T VA+K++KL ++++G TA+REI L++EL
Sbjct: 11 RYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELS 70
Query: 66 HDNIVRLFDVIHTENKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGV 125
H NI+ L D ++ ++LVF+FM+ DL+ + K NS L +K + LQG+
Sbjct: 71 HPNIIGLLDAFGHKSNISLVFDFMETDLEVII----KDNSLV-LTPSHIKAYMLMTLQGL 125
Query: 126 AFCHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLM 185
+ H++ ILHRDLKP NLL++ G LKL DFGLA++FG P ++ +VVT WYRAP++L
Sbjct: 126 EYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLF 185
Query: 186 GSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQLAK 245
G+R Y +D+W+ GCILAE+++ P PG +D +QL IF+T+GTP E+ WP + L
Sbjct: 186 GARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPD 245
Query: 246 YNPLLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPWFA 302
Y + + ++ D+++DL+ GL NP AR++A AL +F+
Sbjct: 246 YVTF------KSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFS 296
>At5g10270 [D] KOG0600 Cdc2-related protein kinase
Length = 505
Score = 228 bits (581), Expect = 8e-60
Identities = 121/312 (38%), Positives = 192/312 (60%), Gaps = 33/312 (10%)
Query: 11 FKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSE-EGTPSTAIREISLMKELKHDNI 69
F++LE++G GTY VY TG VALK++++D+E EG P TAIREI ++K+L H+N+
Sbjct: 26 FEKLEQIGEGTYGQVYMAKEIKTGEIVALKKIRMDNEREGFPITAIREIKILKKLHHENV 85
Query: 70 VRLFDVIHTENK----------------LTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDL 113
++L +++ + + + +VFE+MD+DL D GL +
Sbjct: 86 IQLKEIVTSPGRDRDDQGKPDNNKYKGGIYMVFEYMDHDLTGLADR-------PGLRFTV 138
Query: 114 --VKYFQWQLLQGVAFCHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIP-VNTFS 170
+K + QLL G+ +CH N++LHRD+K NLLI+N G LKL DFGLAR++ +
Sbjct: 139 PQIKCYMKQLLTGLHYCHVNQVLHRDIKGSNLLIDNEGNLKLADFGLARSYSHDHTGNLT 198
Query: 171 SEVVTLWYRAPDVLMGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMG 230
+ V+TLWYR P++L+G+ Y +ID+WS GCI AE++ KP+ PG N++EQL IF+ G
Sbjct: 199 NRVITLWYRPPELLLGATKYGPAIDMWSVGCIFAELLHAKPILPGKNEQEQLNKIFELCG 258
Query: 231 TPVEQTWPQVTQLAKYNPLLPPH-MPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDAR 289
+P E+ WP V+++ +N P + R +++ ++ D + ++LL +L L+P R
Sbjct: 259 SPDEKLWPGVSKMPWFNNFKPARPLKRRVREFFRH-----FDRHALELLEKMLVLDPAQR 313
Query: 290 LSAKDALNHPWF 301
+SAKDAL+ +F
Sbjct: 314 ISAKDALDAEYF 325
>7290565 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 353
Score = 225 bits (573), Expect = 7e-59
Identities = 119/298 (39%), Positives = 184/298 (60%), Gaps = 17/298 (5%)
Query: 10 RFKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKL----DSEEGTPSTAIREISLMKELK 65
R+ +L +G G +ATVYK + T VA+K++K D+ +G TA+REI +++EL+
Sbjct: 11 RYAKLSFLGEGQFATVYKARDTVTNQIVAVKKIKKGSREDARDGINRTALREIKILQELQ 70
Query: 66 HDNIVRLFDVIHTENKLTLVFEFMDNDLKKFM-DNRNKGNSHKGLEMDLVKYFQWQLLQG 124
H+NI+ L DV + ++LVF+FMD DL+ + DN+ L +K + L+G
Sbjct: 71 HENIIGLVDVFGQLSNVSLVFDFMDTDLEVIIKDNKII------LTQANIKAYAIMTLKG 124
Query: 125 VAFCHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVL 184
+ + H N ILHRDLKP NLL+N+ G LK+GDFGLA++FG P ++ VVT WYR+P++L
Sbjct: 125 LEYLHLNWILHRDLKPNNLLVNSDGILKIGDFGLAKSFGSPNRIYTHHVVTRWYRSPELL 184
Query: 185 MGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQLA 244
G+R Y T +D+W+ GCILAE+++ P PG +D +QL IF T+GTP E WP +++L
Sbjct: 185 FGARQYGTGVDMWAVGCILAELMLRVPFMPGDSDLDQLTRIFSTLGTPTEAEWPHLSKLH 244
Query: 245 KYNPLLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPWFA 302
Y R+ +N ++++ L+ L +NP R+S ++AL+ P+FA
Sbjct: 245 DYLQF------RNFPGTPLDNIFTAAGNDLIHLMQRLFAMNPLRRVSCREALSMPYFA 296
>At5g64960 [D] KOG0600 Cdc2-related protein kinase
Length = 513
Score = 224 bits (572), Expect = 9e-59
Identities = 119/312 (38%), Positives = 189/312 (60%), Gaps = 33/312 (10%)
Query: 11 FKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSE-EGTPSTAIREISLMKELKHDNI 69
F++LE++G GTY VY TG VALK++++D+E EG P TAIREI ++K+L H+N+
Sbjct: 26 FEKLEQIGEGTYGQVYMAKEIKTGEIVALKKIRMDNEREGFPITAIREIKILKKLHHENV 85
Query: 70 VRLFDVIHTENK----------------LTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDL 113
+ L +++ + + + +VFE+MD+DL D GL +
Sbjct: 86 IHLKEIVTSPGRDRDDQGKPDNNKYKGGIYMVFEYMDHDLTGLADR-------PGLRFTV 138
Query: 114 --VKYFQWQLLQGVAFCHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIP-VNTFS 170
+K + QLL G+ +CH N++LHRD+K NLLI+N G LKL DFGLAR++ +
Sbjct: 139 PQIKCYMKQLLTGLHYCHVNQVLHRDIKGSNLLIDNEGNLKLADFGLARSYSHDHTGNLT 198
Query: 171 SEVVTLWYRAPDVLMGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMG 230
+ V+TLWYR P++L+G+ Y +ID+WS GCI AE++ GKP+ PG + EQL I++ G
Sbjct: 199 NRVITLWYRPPELLLGATKYGPAIDMWSVGCIFAELLNGKPILPGKTENEQLNKIYELCG 258
Query: 231 TPVEQTWPQVTQLAKYNPLLPPH-MPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDAR 289
+P E WP V+++ YN + + R ++++ ++ D + ++LL +L L+P R
Sbjct: 259 SPDESNWPGVSKMPWYNQMKSSRPLKRRVREIYRH-----FDRHALELLEKMLVLDPSQR 313
Query: 290 LSAKDALNHPWF 301
+ AKDAL+ +F
Sbjct: 314 ICAKDALDAEYF 325
>SPAC2F3.15 [D] KOG0600 Cdc2-related protein kinase
Length = 593
Score = 224 bits (571), Expect = 1e-58
Identities = 114/294 (38%), Positives = 178/294 (59%), Gaps = 12/294 (4%)
Query: 11 FKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSE-EGTPSTAIREISLMKELKHDNI 69
+++++++G GTY VYK +N TG VALK ++L+ E +G P T +RE+ +++ L+H NI
Sbjct: 277 YEKIDQIGEGTYGKVYKAINTVTGDLVALKRIRLEQEKDGFPITTVREVKILQRLRHKNI 336
Query: 70 VRLFDVIHTENKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGVAFCH 129
VRL +++ ++ + +VFE+MD+DL + N S +K+ Q+ + +A+ H
Sbjct: 337 VRLLEIMVEKSSVYMVFEYMDHDLTGVLLN-----SQLHFTPGNIKHLSKQIFEALAYLH 391
Query: 130 ENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNT--FSSEVVTLWYRAPDVLMGS 187
+LHRD+K N+L+NN G LK DFGLAR F + +++ V+TLW+R P++L+G
Sbjct: 392 HRGVLHRDIKGSNILLNNNGDLKFADFGLAR-FNTSSKSANYTNRVITLWFRPPELLLGE 450
Query: 188 RNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQLAKYN 247
Y T++DIWS GCI+ E+ GKP F G ++ QL++I+D MGTP +WP+V L Y
Sbjct: 451 TAYDTAVDIWSAGCIVMELFTGKPFFQGRDEISQLEVIYDMMGTPDVHSWPEVKNLPWYE 510
Query: 248 PLLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPWF 301
L P + K +E+L +DL LL LNP R SA + L H +F
Sbjct: 511 LLKP---VEEKKSRFVETFKEILSPAAIDLCQKLLALNPFCRPSAHETLMHEYF 561
>CE03811 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 763
Score = 220 bits (561), Expect = 2e-57
Identities = 122/304 (40%), Positives = 185/304 (60%), Gaps = 14/304 (4%)
Query: 14 LEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSE-EGTPSTAIREIS-LMKELKHDNIVR 71
L + GTY V++G N T VALK K++ E EG P TA+REI+ L+K H+NIV
Sbjct: 402 LNVIAEGTYGEVFRGKNTRTDEVVALKRFKMEKEKEGFPITALREINMLLKAGAHENIVN 461
Query: 72 LFDVI--HTENKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGVAFCH 129
+ +++ T+ ++ + E++++D+K +D N + K QLL G+ H
Sbjct: 462 VKEILVGSTKTEVYMAMEYVEHDVKSLIDKMRSRNQR--FKTGQQKTLMSQLLSGIEHMH 519
Query: 130 ENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNT-----FSSEVVTLWYRAPDVL 184
+ ILHRDLK NLLI++ G LK+ DFGLAR +G + + VVTLWYR+P++L
Sbjct: 520 KLWILHRDLKTSNLLISHSGILKIADFGLAREYGEARDIEKRMKLTPIVVTLWYRSPELL 579
Query: 185 MGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQLA 244
+ + Y T +D+WS GCI+AE IM KP+F G ++ Q+ IF MGTP EQ WP + +L
Sbjct: 580 LEPKTYSTPVDMWSIGCIMAEFIMMKPMFQGDSEPNQVHQIFQMMGTPTEQIWPDIKELK 639
Query: 245 KYNPL-LPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPWFAE 303
+N + PP P L+++ + E+++++ DLL+G+L LNP RL+A +AL H WF+E
Sbjct: 640 VWNMVEFPPVKPGQLRRIFKG--EKLVNETGFDLLNGMLCLNPANRLTASEALQHDWFSE 697
Query: 304 YNHA 307
+ A
Sbjct: 698 HPKA 701
>7296346 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 952
Score = 219 bits (559), Expect = 3e-57
Identities = 124/302 (41%), Positives = 182/302 (60%), Gaps = 15/302 (4%)
Query: 11 FKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSE-EGTPSTAIREISLMKELKHDNI 69
F+ L ++ GTY VY+ +K T VALK +K++ E EG P T++REI+ + + +H NI
Sbjct: 558 FQCLNRIEEGTYGVVYRAKDKRTNEIVALKRLKMEKEKEGFPITSLREINTLLKGQHPNI 617
Query: 70 VRLFDVIHTEN--KLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGVAF 127
V + +++ N K+ +V +++++DLK M+ N + VK QLL+ VA
Sbjct: 618 VTVREIVVGSNMDKIFIVMDYVEHDLKSLMETMK--NRKQSFFPGEVKCLTQQLLRAVAH 675
Query: 128 CHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGS 187
H+N ILHRDLK NLL++++G LK+GDFGLAR +G P+ ++S VVTLWYRAP++L+ S
Sbjct: 676 LHDNWILHRDLKTSNLLLSHKGILKVGDFGLAREYGSPIKKYTSLVVTLWYRAPELLLCS 735
Query: 188 RNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQLAKYN 247
Y T ID+WS GCI AE + PLFPG ++ ++L IF +GTP E+ WP T+L
Sbjct: 736 PVYSTPIDVWSVGCIFAEFLQMLPLFPGKSEIDELNRIFKELGTPNEKIWPGYTELPAVK 795
Query: 248 PLLPPHMP------RDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPWF 301
+L + L++ Q T E+ + LL GLL +P RLSA AL H +F
Sbjct: 796 NMLSQNSQFTEYPVSQLRKHFQEKTSEM----GLSLLQGLLTYDPKQRLSADAALKHGFF 851
Query: 302 AE 303
E
Sbjct: 852 KE 853
>Hs4502741 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 326
Score = 218 bits (556), Expect = 7e-57
Identities = 126/310 (40%), Positives = 190/310 (60%), Gaps = 23/310 (7%)
Query: 4 LLRYETRFKQLEKVGNGTYATVYKGLN-KTTGVYVALKEVKLDS-EEGTPSTAIREISLM 61
L R + +++ + ++G G Y V+K + K G +VALK V++ + EEG P + IRE++++
Sbjct: 6 LCRADQQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIREVAVL 65
Query: 62 KELK---HDNIVRLFDVIHT-----ENKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDL 113
+ L+ H N+VRLFDV E KLTLVFE +D DL ++D + G+ +
Sbjct: 66 RHLETFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPE----PGVPTET 121
Query: 114 VKYFQWQLLQGVAFCHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEV 173
+K +QLL+G+ F H +R++HRDLKPQN+L+ + GQ+KL DFGLAR + + +S V
Sbjct: 122 IKDMMFQLLRGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQM-ALTSVV 180
Query: 174 VTLWYRAPDVLMGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPV 233
VTLWYRAP+VL+ S +Y T +D+WS GCI AEM KPLF GS+D +QL I D +G P
Sbjct: 181 VTLWYRAPEVLLQS-SYATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIGLPG 239
Query: 234 EQTWPQVTQLAKYNPLLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAK 293
E+ WP+ L + + +++ + + +D+ DLL L NP R+SA
Sbjct: 240 EEDWPRDVALPR--QAFHSKSAQPIEKFVTD-----IDELGKDLLLKCLTFNPAKRISAY 292
Query: 294 DALNHPWFAE 303
AL+HP+F +
Sbjct: 293 SALSHPYFQD 302
>At1g73690 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 398
Score = 218 bits (555), Expect = 9e-57
Identities = 119/293 (40%), Positives = 172/293 (58%), Gaps = 12/293 (4%)
Query: 10 RFKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSE-EGTPSTAIREISLMKELKHDN 68
R+ + E +G GTY V+K + G VA+K+++L E EG TA+REI L+KELKH +
Sbjct: 10 RYLKREVLGQGTYGVVFKATDTKNGETVAIKKIRLGKEKEGVNVTALREIKLLKELKHPH 69
Query: 69 IVRLFDVIHTENKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGVAFC 128
I+ L D + L +VFEFM+ DL+ + +RN S D+ Y Q +L+G+ +C
Sbjct: 70 IIELIDAFPHKENLHIVFEFMETDLEAVIRDRNLYLSPG----DVKSYLQ-MILKGLEYC 124
Query: 129 HENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGSR 188
H +LHRD+KP NLLI GQLKL DFGLAR FG P F+ +V WYRAP++L G++
Sbjct: 125 HGKWVLHRDMKPNNLLIGPNGQLKLADFGLARIFGSPGRKFTHQVFARWYRAPELLFGAK 184
Query: 189 NYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQLAKYNP 248
Y ++D+W+ GCI AE+++ +P G++D +QL IF GTP WP + L Y
Sbjct: 185 QYDGAVDVWAAGCIFAELLLRRPFLQGNSDIDQLSKIFAAFGTPKADQWPDMICLPDYVE 244
Query: 249 LLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPWF 301
P L+ LL +E+ L DLL + +P +R+S + AL H +F
Sbjct: 245 YQFVPAP-SLRSLLPTVSEDAL-----DLLSKMFTYDPKSRISIQQALKHRYF 291
>YDL108w [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 306
Score = 218 bits (554), Expect = 1e-56
Identities = 117/302 (38%), Positives = 176/302 (57%), Gaps = 13/302 (4%)
Query: 5 LRYETRFKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDS-EEGTPSTAIREISLMKE 63
++ + + +KVG GTYA VY G +TG +A+KE+K ++G +AIRE+ ++E
Sbjct: 1 MKVNMEYTKEKKVGEGTYAVVYLGCQHSTGRKIAIKEIKTSEFKDGLDMSAIREVKYLQE 60
Query: 64 LKHDNIVRLFDVIHTENKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQ 123
++H N++ L D+ + L LV EF+ DL+ + K S D +K + L+
Sbjct: 61 MQHPNVIELIDIFMAYDNLNLVLEFLPTDLEVVI----KDKSILFTPAD-IKAWMLMTLR 115
Query: 124 GVAFCHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDV 183
GV CH N ILHRDLKP NLL + GQ+K+ DFGLARA P +S VVT WYRAP++
Sbjct: 116 GVYHCHRNFILHRDLKPNNLLFSPDGQIKVADFGLARAIPAPHEILTSNVVTRWYRAPEL 175
Query: 184 LMGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQL 243
L G+++Y ++IDIWS G I AE+++ P PG ND +Q+++ F +GTP ++ WP+V+
Sbjct: 176 LFGAKHYTSAIDIWSVGVIFAELMLRIPYLPGQNDVDQMEVTFRALGTPTDRDWPEVSSF 235
Query: 244 AKYNPL--LPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPWF 301
YN L PP +L++ +E L D + G+L +NP R +A L +F
Sbjct: 236 MTYNKLQIYPPPSRDELRKRFIAASEYAL-----DFMCGMLTMNPQKRWTAVQCLESDYF 290
Query: 302 AE 303
E
Sbjct: 291 KE 292
>Hs16357496 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 439
Score = 218 bits (554), Expect = 1e-56
Identities = 115/296 (38%), Positives = 179/296 (59%), Gaps = 11/296 (3%)
Query: 11 FKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSE-EGTPSTAIREISLMKELKHDNI 69
F+ L ++ GTY VY+ +K T VALK +K++ E EG P T++REI+ + + +H NI
Sbjct: 82 FQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNI 141
Query: 70 VRLFDVIHTEN--KLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGVAF 127
V + +++ N K+ +V ++++DLK M+ + VK QLL+GV
Sbjct: 142 VTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQP-----FLPGEVKTLMIQLLRGVKH 196
Query: 128 CHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGS 187
H+N ILHRDLK NLL+++ G LK+GDFGLAR +G P+ ++ VVTLWYRAP++L+G+
Sbjct: 197 LHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGA 256
Query: 188 RNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQLAKYN 247
+ Y T++D+WS GCI E++ KPLFPG ++ +Q+ +F +GTP E+ WP ++L
Sbjct: 257 KEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVK 316
Query: 248 PLLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPWFAE 303
+ P + L+ +L D DL++ L P R+SA+D L H +F E
Sbjct: 317 KMTFSEHPYN---NLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRE 369
>Hs16332372 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 771
Score = 218 bits (554), Expect = 1e-56
Identities = 115/296 (38%), Positives = 179/296 (59%), Gaps = 11/296 (3%)
Query: 11 FKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSE-EGTPSTAIREISLMKELKHDNI 69
F+ L ++ GTY VY+ +K T VALK +K++ E EG P T++REI+ + + +H NI
Sbjct: 414 FQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNI 473
Query: 70 VRLFDVIHTEN--KLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGVAF 127
V + +++ N K+ +V ++++DLK M+ + VK QLL+GV
Sbjct: 474 VTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQP-----FLPGEVKTLMIQLLRGVKH 528
Query: 128 CHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGS 187
H+N ILHRDLK NLL+++ G LK+GDFGLAR +G P+ ++ VVTLWYRAP++L+G+
Sbjct: 529 LHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGA 588
Query: 188 RNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQLAKYN 247
+ Y T++D+WS GCI E++ KPLFPG ++ +Q+ +F +GTP E+ WP ++L
Sbjct: 589 KEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVK 648
Query: 248 PLLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPWFAE 303
+ P + L+ +L D DL++ L P R+SA+D L H +F E
Sbjct: 649 KMTFSEHPYN---NLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRE 701
>Hs16332370 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 780
Score = 218 bits (554), Expect = 1e-56
Identities = 115/296 (38%), Positives = 179/296 (59%), Gaps = 11/296 (3%)
Query: 11 FKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSE-EGTPSTAIREISLMKELKHDNI 69
F+ L ++ GTY VY+ +K T VALK +K++ E EG P T++REI+ + + +H NI
Sbjct: 423 FQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNI 482
Query: 70 VRLFDVIHTEN--KLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGVAF 127
V + +++ N K+ +V ++++DLK M+ + VK QLL+GV
Sbjct: 483 VTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQP-----FLPGEVKTLMIQLLRGVKH 537
Query: 128 CHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGS 187
H+N ILHRDLK NLL+++ G LK+GDFGLAR +G P+ ++ VVTLWYRAP++L+G+
Sbjct: 538 LHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGA 597
Query: 188 RNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQLAKYN 247
+ Y T++D+WS GCI E++ KPLFPG ++ +Q+ +F +GTP E+ WP ++L
Sbjct: 598 KEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVK 657
Query: 248 PLLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPWFAE 303
+ P + L+ +L D DL++ L P R+SA+D L H +F E
Sbjct: 658 KMTFSEHPYN---NLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRE 710
>Hs16332368 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 461
Score = 218 bits (554), Expect = 1e-56
Identities = 115/296 (38%), Positives = 179/296 (59%), Gaps = 11/296 (3%)
Query: 11 FKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSE-EGTPSTAIREISLMKELKHDNI 69
F+ L ++ GTY VY+ +K T VALK +K++ E EG P T++REI+ + + +H NI
Sbjct: 104 FQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNI 163
Query: 70 VRLFDVIHTEN--KLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGVAF 127
V + +++ N K+ +V ++++DLK M+ + VK QLL+GV
Sbjct: 164 VTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQP-----FLPGEVKTLMIQLLRGVKH 218
Query: 128 CHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGS 187
H+N ILHRDLK NLL+++ G LK+GDFGLAR +G P+ ++ VVTLWYRAP++L+G+
Sbjct: 219 LHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGA 278
Query: 188 RNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQLAKYN 247
+ Y T++D+WS GCI E++ KPLFPG ++ +Q+ +F +GTP E+ WP ++L
Sbjct: 279 KEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVK 338
Query: 248 PLLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPWFAE 303
+ P + L+ +L D DL++ L P R+SA+D L H +F E
Sbjct: 339 KMTFSEHPYN---NLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRE 391
>Hs16332366 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 565
Score = 218 bits (554), Expect = 1e-56
Identities = 115/296 (38%), Positives = 179/296 (59%), Gaps = 11/296 (3%)
Query: 11 FKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSE-EGTPSTAIREISLMKELKHDNI 69
F+ L ++ GTY VY+ +K T VALK +K++ E EG P T++REI+ + + +H NI
Sbjct: 208 FQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNI 267
Query: 70 VRLFDVIHTEN--KLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGVAF 127
V + +++ N K+ +V ++++DLK M+ + VK QLL+GV
Sbjct: 268 VTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQP-----FLPGEVKTLMIQLLRGVKH 322
Query: 128 CHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGS 187
H+N ILHRDLK NLL+++ G LK+GDFGLAR +G P+ ++ VVTLWYRAP++L+G+
Sbjct: 323 LHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGA 382
Query: 188 RNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQLAKYN 247
+ Y T++D+WS GCI E++ KPLFPG ++ +Q+ +F +GTP E+ WP ++L
Sbjct: 383 KEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVK 442
Query: 248 PLLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPWFAE 303
+ P + L+ +L D DL++ L P R+SA+D L H +F E
Sbjct: 443 KMTFSEHPYN---NLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRE 495
>Hs16332364 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 748
Score = 218 bits (554), Expect = 1e-56
Identities = 115/296 (38%), Positives = 179/296 (59%), Gaps = 11/296 (3%)
Query: 11 FKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSE-EGTPSTAIREISLMKELKHDNI 69
F+ L ++ GTY VY+ +K T VALK +K++ E EG P T++REI+ + + +H NI
Sbjct: 391 FQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNI 450
Query: 70 VRLFDVIHTEN--KLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGVAF 127
V + +++ N K+ +V ++++DLK M+ + VK QLL+GV
Sbjct: 451 VTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQP-----FLPGEVKTLMIQLLRGVKH 505
Query: 128 CHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGS 187
H+N ILHRDLK NLL+++ G LK+GDFGLAR +G P+ ++ VVTLWYRAP++L+G+
Sbjct: 506 LHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGA 565
Query: 188 RNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQLAKYN 247
+ Y T++D+WS GCI E++ KPLFPG ++ +Q+ +F +GTP E+ WP ++L
Sbjct: 566 KEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVK 625
Query: 248 PLLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPWFAE 303
+ P + L+ +L D DL++ L P R+SA+D L H +F E
Sbjct: 626 KMTFSEHPYN---NLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRE 678
>Hs16332362 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 737
Score = 218 bits (554), Expect = 1e-56
Identities = 115/296 (38%), Positives = 179/296 (59%), Gaps = 11/296 (3%)
Query: 11 FKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSE-EGTPSTAIREISLMKELKHDNI 69
F+ L ++ GTY VY+ +K T VALK +K++ E EG P T++REI+ + + +H NI
Sbjct: 380 FQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNI 439
Query: 70 VRLFDVIHTEN--KLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGVAF 127
V + +++ N K+ +V ++++DLK M+ + VK QLL+GV
Sbjct: 440 VTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQP-----FLPGEVKTLMIQLLRGVKH 494
Query: 128 CHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGS 187
H+N ILHRDLK NLL+++ G LK+GDFGLAR +G P+ ++ VVTLWYRAP++L+G+
Sbjct: 495 LHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGA 554
Query: 188 RNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQLAKYN 247
+ Y T++D+WS GCI E++ KPLFPG ++ +Q+ +F +GTP E+ WP ++L
Sbjct: 555 KEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVK 614
Query: 248 PLLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPWFAE 303
+ P + L+ +L D DL++ L P R+SA+D L H +F E
Sbjct: 615 KMTFSEHPYN---NLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRE 667
>Hs16332360 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 526
Score = 218 bits (554), Expect = 1e-56
Identities = 115/296 (38%), Positives = 179/296 (59%), Gaps = 11/296 (3%)
Query: 11 FKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSE-EGTPSTAIREISLMKELKHDNI 69
F+ L ++ GTY VY+ +K T VALK +K++ E EG P T++REI+ + + +H NI
Sbjct: 169 FQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNI 228
Query: 70 VRLFDVIHTEN--KLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGVAF 127
V + +++ N K+ +V ++++DLK M+ + VK QLL+GV
Sbjct: 229 VTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQP-----FLPGEVKTLMIQLLRGVKH 283
Query: 128 CHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGS 187
H+N ILHRDLK NLL+++ G LK+GDFGLAR +G P+ ++ VVTLWYRAP++L+G+
Sbjct: 284 LHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGA 343
Query: 188 RNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQLAKYN 247
+ Y T++D+WS GCI E++ KPLFPG ++ +Q+ +F +GTP E+ WP ++L
Sbjct: 344 KEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVK 403
Query: 248 PLLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPWFAE 303
+ P + L+ +L D DL++ L P R+SA+D L H +F E
Sbjct: 404 KMTFSEHPYN---NLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRE 456
>Hs16332358 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 782
Score = 218 bits (554), Expect = 1e-56
Identities = 115/296 (38%), Positives = 179/296 (59%), Gaps = 11/296 (3%)
Query: 11 FKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSE-EGTPSTAIREISLMKELKHDNI 69
F+ L ++ GTY VY+ +K T VALK +K++ E EG P T++REI+ + + +H NI
Sbjct: 425 FQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNI 484
Query: 70 VRLFDVIHTEN--KLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGVAF 127
V + +++ N K+ +V ++++DLK M+ + VK QLL+GV
Sbjct: 485 VTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQP-----FLPGEVKTLMIQLLRGVKH 539
Query: 128 CHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGS 187
H+N ILHRDLK NLL+++ G LK+GDFGLAR +G P+ ++ VVTLWYRAP++L+G+
Sbjct: 540 LHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGA 599
Query: 188 RNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQLAKYN 247
+ Y T++D+WS GCI E++ KPLFPG ++ +Q+ +F +GTP E+ WP ++L
Sbjct: 600 KEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVK 659
Query: 248 PLLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPWFAE 303
+ P + L+ +L D DL++ L P R+SA+D L H +F E
Sbjct: 660 KMTFSEHPYN---NLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRE 712
>Hs10835055 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 795
Score = 218 bits (554), Expect = 1e-56
Identities = 115/296 (38%), Positives = 179/296 (59%), Gaps = 11/296 (3%)
Query: 11 FKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSE-EGTPSTAIREISLMKELKHDNI 69
F+ L ++ GTY VY+ +K T VALK +K++ E EG P T++REI+ + + +H NI
Sbjct: 438 FQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNI 497
Query: 70 VRLFDVIHTEN--KLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGVAF 127
V + +++ N K+ +V ++++DLK M+ + VK QLL+GV
Sbjct: 498 VTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQP-----FLPGEVKTLMIQLLRGVKH 552
Query: 128 CHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGS 187
H+N ILHRDLK NLL+++ G LK+GDFGLAR +G P+ ++ VVTLWYRAP++L+G+
Sbjct: 553 LHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGA 612
Query: 188 RNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQLAKYN 247
+ Y T++D+WS GCI E++ KPLFPG ++ +Q+ +F +GTP E+ WP ++L
Sbjct: 613 KEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVK 672
Query: 248 PLLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPWFAE 303
+ P + L+ +L D DL++ L P R+SA+D L H +F E
Sbjct: 673 KMTFSEHPYN---NLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRE 725
>At1g66750 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 348
Score = 217 bits (553), Expect = 1e-56
Identities = 116/294 (39%), Positives = 170/294 (57%), Gaps = 12/294 (4%)
Query: 10 RFKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSE-EGTPSTAIREISLMKELKHDN 68
R+ + + +G GTY VYK + TG VA+K+++L ++ EG TA+REI L+KEL H +
Sbjct: 12 RYLRRQILGEGTYGVVYKATDTKTGKTVAVKKIRLGNQKEGVNFTALREIKLLKELNHPH 71
Query: 69 IVRLFDVIHTENKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGVAFC 128
IV L D + L LVFE+M DL+ + +RN L +K + L+G+A+C
Sbjct: 72 IVELIDAFPHDGSLHLVFEYMQTDLEAVIRDRNIF-----LSPGDIKSYMLMTLKGLAYC 126
Query: 129 HENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGSR 188
H+ +LHRD+KP NLLI G LKL DFGLAR FG P F+ +V WYRAP++L GSR
Sbjct: 127 HKKWVLHRDMKPNNLLIGENGLLKLADFGLARLFGSPNRRFTHQVFATWYRAPELLFGSR 186
Query: 189 NYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQLAKYNP 248
Y +D+W+ GCI AE+++ +P PGS + +QL IF GTPV W + L Y
Sbjct: 187 QYGAGVDVWAAGCIFAELLLRRPFLPGSTEIDQLGKIFQAFGTPVPSQWSDMIYLPDYME 246
Query: 249 LLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPWFA 302
P L+ + + D+ +DLL + +P R++ + AL+H +F+
Sbjct: 247 FSYTPAP-PLRTIF-----PMASDDALDLLAKMFIYDPRQRITIQQALDHRYFS 294
>At1g18040 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 391
Score = 216 bits (549), Expect = 4e-56
Identities = 116/293 (39%), Positives = 172/293 (58%), Gaps = 12/293 (4%)
Query: 10 RFKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSE-EGTPSTAIREISLMKELKHDN 68
R+ + E +G GTY V+K + T VA+K+++L + EG TA+REI ++KELKH +
Sbjct: 11 RYLKQEVLGQGTYGVVFKATDTKTEQTVAIKKIRLGKQREGVNITALREIKMLKELKHPH 70
Query: 69 IVRLFDVIHTENKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGVAFC 128
I+ L D + L LVFEFM+ DL+ + + N S ++ L+ F+ G+A+C
Sbjct: 71 IILLIDAFPHKENLHLVFEFMETDLEAVIRDSNIFLSPADIKSYLLMTFK-----GLAYC 125
Query: 129 HENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGSR 188
H+ +LHRD+KP NLLI GQLKL DFGLAR FG P F+ +V WYRAP++L G++
Sbjct: 126 HDKWVLHRDMKPNNLLIGVDGQLKLADFGLARIFGSPNRKFTHQVFARWYRAPELLFGAK 185
Query: 189 NYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQLAKYNP 248
Y ++D+W+ CI AE+++ +P G++D +QL IF GTP WP +T+L Y
Sbjct: 186 QYGAAVDVWAVACIFAELLLRRPFLQGNSDIDQLSKIFAAFGTPKADQWPDLTKLPDYVE 245
Query: 249 LLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPWF 301
P L+ L + D+ +DLL + +P AR+S K AL H +F
Sbjct: 246 YQFVPAP-SLRSLF-----PAVSDDALDLLSKMFTYDPKARISIKQALEHRYF 292
>Hs16357498 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 777
Score = 215 bits (548), Expect = 6e-56
Identities = 114/296 (38%), Positives = 179/296 (59%), Gaps = 11/296 (3%)
Query: 11 FKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSE-EGTPSTAIREISLMKELKHDNI 69
F+ L ++ GTY VY+ +K T VALK +K++ E EG P T++REI+ + + +H NI
Sbjct: 420 FQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNI 479
Query: 70 VRLFDVIHTEN--KLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGVAF 127
V + +++ N K+ +V ++++DLK M+ + VK QLL+GV
Sbjct: 480 VTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQP-----FLPGEVKTLMIQLLRGVKH 534
Query: 128 CHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGS 187
H+N ILHRDLK NLL+++ G LK+GDFGLAR +G P+ ++ VVT WYRAP++L+G+
Sbjct: 535 LHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGA 594
Query: 188 RNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQLAKYN 247
+ Y T++D+WS GCI E++ KPLFPG+++ +Q+ +F +GTP E+ WP ++L
Sbjct: 595 KEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVK 654
Query: 248 PLLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPWFAE 303
+ P + L+ +L D DL++ L P R+SA+D L H +F E
Sbjct: 655 KMTFSEHPYN---NLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRE 707
>Hs16357486 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 780
Score = 215 bits (548), Expect = 6e-56
Identities = 114/296 (38%), Positives = 179/296 (59%), Gaps = 11/296 (3%)
Query: 11 FKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSE-EGTPSTAIREISLMKELKHDNI 69
F+ L ++ GTY VY+ +K T VALK +K++ E EG P T++REI+ + + +H NI
Sbjct: 423 FQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNI 482
Query: 70 VRLFDVIHTEN--KLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGVAF 127
V + +++ N K+ +V ++++DLK M+ + VK QLL+GV
Sbjct: 483 VTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQP-----FLPGEVKTLMIQLLRGVKH 537
Query: 128 CHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGS 187
H+N ILHRDLK NLL+++ G LK+GDFGLAR +G P+ ++ VVT WYRAP++L+G+
Sbjct: 538 LHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGA 597
Query: 188 RNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQLAKYN 247
+ Y T++D+WS GCI E++ KPLFPG+++ +Q+ +F +GTP E+ WP ++L
Sbjct: 598 KEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVK 657
Query: 248 PLLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPWFAE 303
+ P + L+ +L D DL++ L P R+SA+D L H +F E
Sbjct: 658 KMTFSEHPYN---NLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRE 710
>Hs16357484 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 767
Score = 215 bits (548), Expect = 6e-56
Identities = 114/296 (38%), Positives = 179/296 (59%), Gaps = 11/296 (3%)
Query: 11 FKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSE-EGTPSTAIREISLMKELKHDNI 69
F+ L ++ GTY VY+ +K T VALK +K++ E EG P T++REI+ + + +H NI
Sbjct: 410 FQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNI 469
Query: 70 VRLFDVIHTEN--KLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGVAF 127
V + +++ N K+ +V ++++DLK M+ + VK QLL+GV
Sbjct: 470 VTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQP-----FLPGEVKTLMIQLLRGVKH 524
Query: 128 CHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGS 187
H+N ILHRDLK NLL+++ G LK+GDFGLAR +G P+ ++ VVT WYRAP++L+G+
Sbjct: 525 LHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGA 584
Query: 188 RNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQLAKYN 247
+ Y T++D+WS GCI E++ KPLFPG+++ +Q+ +F +GTP E+ WP ++L
Sbjct: 585 KEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVK 644
Query: 248 PLLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPWFAE 303
+ P + L+ +L D DL++ L P R+SA+D L H +F E
Sbjct: 645 KMTFSEHPYN---NLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRE 697
>Hs16357482 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 776
Score = 215 bits (548), Expect = 6e-56
Identities = 114/296 (38%), Positives = 179/296 (59%), Gaps = 11/296 (3%)
Query: 11 FKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSE-EGTPSTAIREISLMKELKHDNI 69
F+ L ++ GTY VY+ +K T VALK +K++ E EG P T++REI+ + + +H NI
Sbjct: 419 FQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNI 478
Query: 70 VRLFDVIHTEN--KLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGVAF 127
V + +++ N K+ +V ++++DLK M+ + VK QLL+GV
Sbjct: 479 VTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQP-----FLPGEVKTLMIQLLRGVKH 533
Query: 128 CHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGS 187
H+N ILHRDLK NLL+++ G LK+GDFGLAR +G P+ ++ VVT WYRAP++L+G+
Sbjct: 534 LHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGA 593
Query: 188 RNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQLAKYN 247
+ Y T++D+WS GCI E++ KPLFPG+++ +Q+ +F +GTP E+ WP ++L
Sbjct: 594 KEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVK 653
Query: 248 PLLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPWFAE 303
+ P + L+ +L D DL++ L P R+SA+D L H +F E
Sbjct: 654 KMTFSEHPYN---NLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRE 706
>Hs16357480 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 397
Score = 215 bits (548), Expect = 6e-56
Identities = 114/296 (38%), Positives = 179/296 (59%), Gaps = 11/296 (3%)
Query: 11 FKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSE-EGTPSTAIREISLMKELKHDNI 69
F+ L ++ GTY VY+ +K T VALK +K++ E EG P T++REI+ + + +H NI
Sbjct: 40 FQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNI 99
Query: 70 VRLFDVIHTEN--KLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGVAF 127
V + +++ N K+ +V ++++DLK M+ + VK QLL+GV
Sbjct: 100 VTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQP-----FLPGEVKTLMIQLLRGVKH 154
Query: 128 CHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGS 187
H+N ILHRDLK NLL+++ G LK+GDFGLAR +G P+ ++ VVT WYRAP++L+G+
Sbjct: 155 LHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGA 214
Query: 188 RNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQLAKYN 247
+ Y T++D+WS GCI E++ KPLFPG+++ +Q+ +F +GTP E+ WP ++L
Sbjct: 215 KEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVK 274
Query: 248 PLLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPWFAE 303
+ P + L+ +L D DL++ L P R+SA+D L H +F E
Sbjct: 275 KMTFSEHPYN---NLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRE 327
>7296451 [D] KOG0600 Cdc2-related protein kinase
Length = 1157
Score = 214 bits (545), Expect = 1e-55
Identities = 117/308 (37%), Positives = 183/308 (58%), Gaps = 22/308 (7%)
Query: 11 FKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSE-EGTPSTAIREISLMKELKHDNI 69
F+ + ++G GTY VYK + T VALK+V+L+ E EG P TA+REI ++++L H NI
Sbjct: 804 FEMIAQIGEGTYGQVYKARDHHTNDMVALKKVRLEHEKEGFPITAVREIKILRQLNHRNI 863
Query: 70 VRLFDVI----------HTENKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQW 119
V L +++ + LVFE+MD+DL +++ + + ++K
Sbjct: 864 VNLHEIVTDKQDAVEFRKDKGSFYLVFEYMDHDLMGLLESGMVDFNEEN-NASIMK---- 918
Query: 120 QLLQGVAFCHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIP--VNTFSSEVVTLW 177
QLL G+ +CH+ LHRD+K N+L+NNRG++KL DFGLAR + ++++V+TLW
Sbjct: 919 QLLDGLNYCHKKNFLHRDIKCSNILMNNRGKVKLADFGLARLYNADDRERPYTNKVITLW 978
Query: 178 YRAPDVLMGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTW 237
YR P++L+G Y SID+WSCGCIL E+ + +PLF + + QL+ I G+PV W
Sbjct: 979 YRPPELLLGEERYGPSIDVWSCGCILGELFVKRPLFQANAEMAQLETISKICGSPVPAVW 1038
Query: 238 PQVTQLAKYNPLLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALN 297
P V +L ++ L R ++L ++ E + +DLL +L L+PD R++A+DAL
Sbjct: 1039 PNVIKLPLFHTLKQKKTHR--RRLRED--FEFMPAPALDLLDKMLDLDPDKRITAEDALR 1094
Query: 298 HPWFAEYN 305
PW + N
Sbjct: 1095 SPWLRKIN 1102
>Hs16357494 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 775
Score = 214 bits (544), Expect = 2e-55
Identities = 113/296 (38%), Positives = 179/296 (60%), Gaps = 11/296 (3%)
Query: 11 FKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSE-EGTPSTAIREISLMKELKHDNI 69
F+ L ++ GTY VY+ +K T VALK +K++ E EG P T++REI+ + + +H NI
Sbjct: 418 FQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKENEGFPITSLREINTILKAQHPNI 477
Query: 70 VRLFDVIHTEN--KLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGVAF 127
V + +++ N K+ +V ++++DLK M+ + VK QLL+GV
Sbjct: 478 VTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQP-----FLPGEVKTLMIQLLRGVKH 532
Query: 128 CHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGS 187
H+N ILHRDLK NLL+++ G LK+GDFGLAR +G P+ ++ VVT WYRAP++L+G+
Sbjct: 533 LHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGA 592
Query: 188 RNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQLAKYN 247
+ Y T++D+WS GCI E++ KPLFPG+++ +Q+ +F +GTP E+ WP ++L
Sbjct: 593 KEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVK 652
Query: 248 PLLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPWFAE 303
+ P + L+ +L + DL++ L P R+SA+D L H +F E
Sbjct: 653 KMTFSEHPYN---NLRKRFGALLSEQGFDLMNKFLTYFPGRRISAEDGLKHEYFRE 705
>Hs16357492 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 777
Score = 214 bits (544), Expect = 2e-55
Identities = 113/296 (38%), Positives = 179/296 (60%), Gaps = 11/296 (3%)
Query: 11 FKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSE-EGTPSTAIREISLMKELKHDNI 69
F+ L ++ GTY VY+ +K T VALK +K++ E EG P T++REI+ + + +H NI
Sbjct: 420 FQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKENEGFPITSLREINTILKAQHPNI 479
Query: 70 VRLFDVIHTEN--KLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGVAF 127
V + +++ N K+ +V ++++DLK M+ + VK QLL+GV
Sbjct: 480 VTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQP-----FLPGEVKTLMIQLLRGVKH 534
Query: 128 CHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGS 187
H+N ILHRDLK NLL+++ G LK+GDFGLAR +G P+ ++ VVT WYRAP++L+G+
Sbjct: 535 LHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGA 594
Query: 188 RNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQLAKYN 247
+ Y T++D+WS GCI E++ KPLFPG+++ +Q+ +F +GTP E+ WP ++L
Sbjct: 595 KEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVK 654
Query: 248 PLLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPWFAE 303
+ P + L+ +L + DL++ L P R+SA+D L H +F E
Sbjct: 655 KMTFSEHPYN---NLRKRFGALLSEQGFDLMNKFLTYFPGRRISAEDGLKHEYFRE 707
>7291442 [D] KOG0669 Cyclin T-dependent kinase CDK9
Length = 404
Score = 213 bits (543), Expect = 2e-55
Identities = 123/314 (39%), Positives = 180/314 (57%), Gaps = 23/314 (7%)
Query: 3 PLLRYETRFKQLEKVGNGTYATVYKGLNKTTGV-YVALKEVKLDSE-EGTPSTAIREISL 60
P +++++ K+G GT+ V+K K +VA+K+V +D+E EG P TA+REI +
Sbjct: 42 PYCDESNKYEKVAKIGQGTFGEVFKAREKKGNKKFVAMKKVLMDNEKEGFPITALREIRI 101
Query: 61 MKELKHDNIVRLFDVIHTENKLT--------LVFEFMDNDLKKFMDNRNKGNSHKGLEMD 112
++ LKH+N+V L ++ T+ T LVF+F ++DL + N N S +
Sbjct: 102 LQLLKHENVVNLIEICRTKATATNGYRSTFYLVFDFCEHDLAGLLSNMNVKFS-----LG 156
Query: 113 LVKYFQWQLLQGVAFCHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNT---- 168
+K QLL G+ + H N+ILHRD+K N+LI G LKL DFGLARAF IP N
Sbjct: 157 EIKKVMQQLLNGLYYIHSNKILHRDMKAANVLITKHGILKLADFGLARAFSIPKNESKNR 216
Query: 169 FSSEVVTLWYRAPDVLMGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDT 228
+++ VVTLWYR P++L+G RNY +D+W GCI+AEM P+ G+ +++QL I
Sbjct: 217 YTNRVVTLWYRPPELLLGDRNYGPPVDMWGAGCIMAEMWTRSPIMQGNTEQQQLTFISQL 276
Query: 229 MGTPVEQTWPQVTQLAKYNPL-LPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPD 287
G+ WP V +L Y + LP + R +K+ L+ V D DLL LL L+P
Sbjct: 277 CGSFTPDVWPGVEELELYKSIELPKNQKRRVKERLR---PYVKDQTGCDLLDKLLTLDPK 333
Query: 288 ARLSAKDALNHPWF 301
R+ A ALNH +F
Sbjct: 334 KRIDADTALNHDFF 347
>YGR040w [T] KOG0660 Mitogen-activated protein kinase
Length = 368
Score = 211 bits (537), Expect = 1e-54
Identities = 117/312 (37%), Positives = 187/312 (59%), Gaps = 20/312 (6%)
Query: 9 TRFKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPSTAIREISLMKEL-KHD 67
+++K ++ +G G Y TV ++K +G+ VA+K+++ S++ + IREI L++ +H+
Sbjct: 11 SQYKLVDLIGEGAYGTVCSAIHKPSGIKVAIKKIQPFSKKLFVTRTIREIKLLRYFHEHE 70
Query: 68 NIVRLFDVIHTE-----NKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLL 122
NI+ + D + N + LV E M+ DL+K ++N+N G S L D V+YF +Q+L
Sbjct: 71 NIISILDKVRPVSIDKLNAVYLVEELMETDLQKVINNQNSGFST--LSDDHVQYFTYQIL 128
Query: 123 QGVAFCHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIP-------VNTFSSEVVT 175
+ + H +++HRD+KP NLL+N+ LK+ DFGLAR V + V T
Sbjct: 129 RALKSIHSAQVIHRDIKPSNLLLNSNCDLKVCDFGLARCLASSSDSRETLVGFMTEYVAT 188
Query: 176 LWYRAPDVLMGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQ 235
WYRAP++++ + Y T++DIWSCGCILAEM+ GKPLFPG + QL LI + +GTP +
Sbjct: 189 RWYRAPEIMLTFQEYTTAMDIWSCGCILAEMVSGKPLFPGRDYHHQLWLILEVLGTPSFE 248
Query: 236 TWPQV--TQLAKYNPLLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAK 293
+ Q+ + +Y LP P + + L+ +++DLL +LQ NPD R+SA
Sbjct: 249 DFNQIKSKRAKEYIANLPMRPPLPWETVWSKTD---LNPDMIDLLDKMLQFNPDKRISAA 305
Query: 294 DALNHPWFAEYN 305
+AL HP+ A Y+
Sbjct: 306 EALRHPYLAMYH 317
>Hs14110390 [D] KOG0600 Cdc2-related protein kinase
Length = 1452
Score = 210 bits (535), Expect = 2e-54
Identities = 116/301 (38%), Positives = 178/301 (58%), Gaps = 25/301 (8%)
Query: 10 RFKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSE-EGTPSTAIREISLMKELKHDN 68
+F + +G GTY VYK +K TG VALK+V+LD+E EG P TAIREI ++++L H +
Sbjct: 704 KFDIIGIIGEGTYGQVYKARDKDTGEMVALKKVRLDNEKEGFPITAIREIKILRQLTHQS 763
Query: 69 IVRLFDVI----------HTENKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQ 118
I+ + +++ + LVFE+MD+DL +++ G H + +K F
Sbjct: 764 IINMKEIVTDKEDALDFKKDKGAFYLVFEYMDHDLMGLLES---GLVH--FNENHIKSFM 818
Query: 119 WQLLQGVAFCHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNT-FSSEVVTLW 177
QL++G+ +CH+ LHRD+K N+L+NNRGQ+KL DFGLAR + + ++++V+TLW
Sbjct: 819 RQLMEGLDYCHKKNFLHRDIKCSNILLNNRGQIKLADFGLARLYSSEESRPYTNKVITLW 878
Query: 178 YRAPDVLMGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTW 237
YR P++L+G Y +ID+WSCGCIL E+ KP+F + + QL+LI G+P W
Sbjct: 879 YRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANQELAQLELISRICGSPCPAVW 938
Query: 238 PQVTQLAKYNPLLPPHMPRDLKQLLQNNTEE--VLDDNVVDLLHGLLQLNPDARLSAKDA 295
P V +L +N + P KQ + EE + +DL +L L+P R +A+ A
Sbjct: 939 PDVIKLPYFNTMKPK------KQYRRKLREEFVFIPAAALDLFDYMLALDPSKRCTAEQA 992
Query: 296 L 296
L
Sbjct: 993 L 993
>Hs14110387 [D] KOG0600 Cdc2-related protein kinase
Length = 1512
Score = 210 bits (535), Expect = 2e-54
Identities = 116/301 (38%), Positives = 178/301 (58%), Gaps = 25/301 (8%)
Query: 10 RFKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSE-EGTPSTAIREISLMKELKHDN 68
+F + +G GTY VYK +K TG VALK+V+LD+E EG P TAIREI ++++L H +
Sbjct: 704 KFDIIGIIGEGTYGQVYKARDKDTGEMVALKKVRLDNEKEGFPITAIREIKILRQLTHQS 763
Query: 69 IVRLFDVI----------HTENKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQ 118
I+ + +++ + LVFE+MD+DL +++ G H + +K F
Sbjct: 764 IINMKEIVTDKEDALDFKKDKGAFYLVFEYMDHDLMGLLES---GLVH--FNENHIKSFM 818
Query: 119 WQLLQGVAFCHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNT-FSSEVVTLW 177
QL++G+ +CH+ LHRD+K N+L+NNRGQ+KL DFGLAR + + ++++V+TLW
Sbjct: 819 RQLMEGLDYCHKKNFLHRDIKCSNILLNNRGQIKLADFGLARLYSSEESRPYTNKVITLW 878
Query: 178 YRAPDVLMGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTW 237
YR P++L+G Y +ID+WSCGCIL E+ KP+F + + QL+LI G+P W
Sbjct: 879 YRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANQELAQLELISRICGSPCPAVW 938
Query: 238 PQVTQLAKYNPLLPPHMPRDLKQLLQNNTEE--VLDDNVVDLLHGLLQLNPDARLSAKDA 295
P V +L +N + P KQ + EE + +DL +L L+P R +A+ A
Sbjct: 939 PDVIKLPYFNTMKPK------KQYRRKLREEFVFIPAAALDLFDYMLALDPSKRCTAEQA 992
Query: 296 L 296
L
Sbjct: 993 L 993
>Hs7706549 [D] KOG0600 Cdc2-related protein kinase
Length = 1490
Score = 209 bits (531), Expect = 5e-54
Identities = 116/301 (38%), Positives = 177/301 (58%), Gaps = 25/301 (8%)
Query: 10 RFKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSE-EGTPSTAIREISLMKELKHDN 68
+F + +G GTY VYK +K TG VALK+V+LD+E EG P TAIREI ++++L H +
Sbjct: 726 KFDIIGIIGEGTYGQVYKARDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQLIHRS 785
Query: 69 IVRLFDVI----------HTENKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQ 118
+V + +++ + LVFE+MD+DL +++ G H D +K F
Sbjct: 786 VVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLES---GLVH--FSEDHIKSFM 840
Query: 119 WQLLQGVAFCHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNT-FSSEVVTLW 177
QL++G+ +CH+ LHRD+K N+L+NN GQ+KL DFGLAR + + ++++V+TLW
Sbjct: 841 KQLMEGLEYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRPYTNKVITLW 900
Query: 178 YRAPDVLMGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTW 237
YR P++L+G Y +ID+WSCGCIL E+ KP+F + + QL+LI G+P W
Sbjct: 901 YRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVW 960
Query: 238 PQVTQLAKYNPLLPPHMPRDLKQLLQNNTEE--VLDDNVVDLLHGLLQLNPDARLSAKDA 295
P V +L +N + P KQ + EE + +DLL +L L+P R +A+
Sbjct: 961 PDVIKLPYFNTMKPK------KQYRRRLREEFSFIPSAALDLLDHMLTLDPSKRCTAEQT 1014
Query: 296 L 296
L
Sbjct: 1015 L 1015
>Hs4502735 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 303
Score = 207 bits (527), Expect = 2e-53
Identities = 120/304 (39%), Positives = 180/304 (58%), Gaps = 25/304 (8%)
Query: 9 TRFKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSEEG----TPSTAIREISLMKEL 64
+R++ + ++G G Y TVYK + +G +VALK V++ + G P + +RE++L++ L
Sbjct: 4 SRYEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGGGGGGLPISTVREVALLRRL 63
Query: 65 K---HDNIVRLFDVIHT-----ENKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKY 116
+ H N+VRL DV T E K+TLVFE +D DL+ ++D GL + +K
Sbjct: 64 EAFEHPNVVRLMDVCATSRTDREIKVTLVFEHVDQDLRTYLDKAPP----PGLPAETIKD 119
Query: 117 FQWQLLQGVAFCHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTL 176
Q L+G+ F H N I+HRDLKP+N+L+ + G +KL DFGLAR + + + VVTL
Sbjct: 120 LMRQFLRGLDFLHANCIVHRDLKPENILVTSGGTVKLADFGLARIYSYQM-ALTPVVVTL 178
Query: 177 WYRAPDVLMGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQT 236
WYRAP+VL+ S Y T +D+WS GCI AEM KPLF G+++ +QL IFD +G P E
Sbjct: 179 WYRAPEVLLQS-TYATPVDMWSVGCIFAEMFRRKPLFCGNSEADQLGKIFDLIGLPPEDD 237
Query: 237 WPQVTQLAKYNPLLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDAL 296
WP+ L + PP PR ++ ++ ++++ LL +L NP R+SA AL
Sbjct: 238 WPRDVSLPR--GAFPPRGPRPVQSVVPE-----MEESGAQLLLEMLTFNPHKRISAFRAL 290
Query: 297 NHPW 300
H +
Sbjct: 291 QHSY 294
>Hs4502731 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 360
Score = 207 bits (527), Expect = 2e-53
Identities = 118/300 (39%), Positives = 181/300 (60%), Gaps = 20/300 (6%)
Query: 11 FKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSE-EGTPSTAIREISLMKELKHDNI 69
F++L ++G GTY VY+ + T VALK+V++D E +G P +++REI+L+ L+H NI
Sbjct: 39 FEKLNRIGEGTYGIVYRARDTQTDEIVALKKVRMDKEKDGIPISSLREITLLLRLRHPNI 98
Query: 70 VRLFDVI---HTENKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGVA 126
V L +V+ H E+ + LV + + DL ++N S VK Q+L+G+
Sbjct: 99 VELKEVVVGNHLES-IFLVMGYCEQDLASLLENMPTPFSEAQ-----VKCIVLQVLRGLQ 152
Query: 127 FCHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMG 186
+ H N I+HRDLK NLL+ ++G +K DFGLARA+G+PV + +VVTLWYRAP++L+G
Sbjct: 153 YLHRNFIIHRDLKVSNLLMTDKGCVKTADFGLARAYGVPVKPMTPKVVTLWYRAPELLLG 212
Query: 187 SRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQLAKY 246
+ TSID+W+ GCILAE++ +PL PG+++ Q+ LI +GTP E WP ++L
Sbjct: 213 TTTQTTSIDMWAVGCILAELLAHRPLLPGTSEIHQIDLIVQLLGTPSENIWPGFSKL--- 269
Query: 247 NPLLPPHMPRDLKQLLQNNTEEV---LDDNVVDLLHGLLQLNPDARLSAKDALNHPWFAE 303
PL+ + L++ NN + L + + LLH L +P R +A D L +F E
Sbjct: 270 -PLVGQY---SLRKQPYNNLKHKFPWLSEAGLRLLHFLFMYDPKKRATAGDCLESSYFKE 325
>Hs16950647 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 314
Score = 207 bits (527), Expect = 2e-53
Identities = 118/300 (39%), Positives = 181/300 (60%), Gaps = 20/300 (6%)
Query: 11 FKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSE-EGTPSTAIREISLMKELKHDNI 69
F++L ++G GTY VY+ + T VALK+V++D E +G P +++REI+L+ L+H NI
Sbjct: 10 FEKLNRIGEGTYGIVYRARDTQTDEIVALKKVRMDKEKDGIPISSLREITLLLRLRHPNI 69
Query: 70 VRLFDVI---HTENKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGVA 126
V L +V+ H E+ + LV + + DL ++N S VK Q+L+G+
Sbjct: 70 VELKEVVVGNHLES-IFLVMGYCEQDLASLLENMPTPFSEAQ-----VKCIVLQVLRGLQ 123
Query: 127 FCHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMG 186
+ H N I+HRDLK NLL+ ++G +K DFGLARA+G+PV + +VVTLWYRAP++L+G
Sbjct: 124 YLHRNFIIHRDLKVSNLLMTDKGCVKTADFGLARAYGVPVKPMTPKVVTLWYRAPELLLG 183
Query: 187 SRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQLAKY 246
+ TSID+W+ GCILAE++ +PL PG+++ Q+ LI +GTP E WP ++L
Sbjct: 184 TTTQTTSIDMWAVGCILAELLAHRPLLPGTSEIHQIDLIVQLLGTPSENIWPGFSKL--- 240
Query: 247 NPLLPPHMPRDLKQLLQNNTEEV---LDDNVVDLLHGLLQLNPDARLSAKDALNHPWFAE 303
PL+ + L++ NN + L + + LLH L +P R +A D L +F E
Sbjct: 241 -PLVGQY---SLRKQPYNNLKHKFPWLSEAGLRLLHFLFMYDPKKRATAGDCLESSYFKE 296
>Hs4502747 [D] KOG0669 Cyclin T-dependent kinase CDK9
Length = 372
Score = 206 bits (525), Expect = 3e-53
Identities = 117/307 (38%), Positives = 177/307 (57%), Gaps = 22/307 (7%)
Query: 9 TRFKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSE-EGTPSTAIREISLMKELKHD 67
+++++L K+G GT+ V+K ++ TG VALK+V +++E EG P TA+REI +++ LKH+
Sbjct: 17 SKYEKLAKIGQGTFGEVFKARHRKTGQKVALKKVLMENEKEGFPITALREIKILQLLKHE 76
Query: 68 NIVRLFDVIHTE--------NKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQW 119
N+V L ++ T+ + LVF+F ++DL + N + +K
Sbjct: 77 NVVNLIEICRTKASPYNRCKGSIYLVFDFCEHDLAGLLSN-----VLVKFTLSEIKRVMQ 131
Query: 120 QLLQGVAFCHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNT----FSSEVVT 175
LL G+ + H N+ILHRD+K N+LI G LKL DFGLARAF + N+ +++ VVT
Sbjct: 132 MLLNGLYYIHRNKILHRDMKAANVLITRDGVLKLADFGLARAFSLAKNSQPNRYTNRVVT 191
Query: 176 LWYRAPDVLMGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQ 235
LWYR P++L+G R+Y ID+W GCI+AEM P+ G+ ++ QL LI G+ +
Sbjct: 192 LWYRPPELLLGERDYGPPIDLWGAGCIMAEMWTRSPIMQGNTEQHQLALISQLCGSITPE 251
Query: 236 TWPQVTQLAKYNPL-LPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKD 294
WP V Y L L R +K L+ V D +DL+ LL L+P R+ + D
Sbjct: 252 VWPNVDNYELYEKLELVKGQKRKVKDRLK---AYVRDPYALDLIDKLLVLDPAQRIDSDD 308
Query: 295 ALNHPWF 301
ALNH +F
Sbjct: 309 ALNHDFF 315
>ECU08g0230 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 265
Score = 206 bits (524), Expect = 3e-53
Identities = 108/223 (48%), Positives = 152/223 (67%), Gaps = 9/223 (4%)
Query: 9 TRFKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPSTAIREISLMKELKHDN 68
TR+ +G+GTY VY+ ++ T VALK ++L+ +EG P TA+REIS++K+L H N
Sbjct: 2 TRYILGALIGSGTYGEVYEAIDTETKEKVALKRIRLNEKEGMPGTALREISILKKLSHRN 61
Query: 69 IVRLFDVIHTENKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGVAFC 128
I+ L +IHT+ LT+VF F+D +LKK++ N+ K + M+LV QL+ GV +
Sbjct: 62 IISLVSIIHTDALLTMVFPFIDYELKKYIGM----NTGKNI-MELVN----QLICGVHYL 112
Query: 129 HENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGSR 188
H ++HRDLKPQN+L+ + G LK+ DFGL+R+ I V +SSEVVTLWYR+P++LMGS
Sbjct: 113 HRMNVVHRDLKPQNILVTSDGVLKIADFGLSRSLEIRVPPYSSEVVTLWYRSPELLMGST 172
Query: 189 NYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGT 231
+Y +DIWS GCI+ EMI +PLFPG + E QL LI GT
Sbjct: 173 SYRFYVDIWSLGCIIYEMITLEPLFPGESKENQLTLIRRKAGT 215
>SPBC19F8.07 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 335
Score = 202 bits (515), Expect = 4e-52
Identities = 113/290 (38%), Positives = 172/290 (58%), Gaps = 15/290 (5%)
Query: 16 KVGNGTYATVYKGLNKTTGVYVALKEVKLDS-EEGTPSTAIREISLMKELKHDNIVRLFD 74
KVG GTYA V+ G K T VA+K++K+ ++G +A+REI ++E +HDN++ L D
Sbjct: 16 KVGEGTYAVVFLGRQKETNRRVAIKKIKVGQFKDGIDISALREIKFLRESRHDNVIELVD 75
Query: 75 VIHTENKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGVAFCHENRIL 134
V T++ L ++ EF+D+DL+ + ++ + +K + LL+G+ H IL
Sbjct: 76 VFSTKSNLNIILEFLDSDLEMLIKDK-----FIVFQPAHIKSWMVMLLRGLHHIHSRFIL 130
Query: 135 HRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGSRNYCTSI 194
HRDLKP NLLI++ G LKL DFGL+R FG P + S +V+T WYR P++ MG R+Y T +
Sbjct: 131 HRDLKPNNLLISSDGVLKLADFGLSRDFGTPSH-MSHQVITRWYRPPELFMGCRSYGTGV 189
Query: 195 DIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQLAKYNPL--LPP 252
D+WS GCI AE+++ P PG +D +QL +IF +GTP + + QL Y + +PP
Sbjct: 190 DMWSVGCIFAELMLRTPYLPGESDLDQLNVIFRALGTPEPEVIKSMQQLPNYVEMKHIPP 249
Query: 253 HMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPWFA 302
P + L + +DLL +L NP R +A+ AL H +F+
Sbjct: 250 --PNGGMEALFS----AAGHEEIDLLKMMLDYNPYRRPTAQQALEHHYFS 293
>7302908 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 317
Score = 202 bits (514), Expect = 5e-52
Identities = 118/303 (38%), Positives = 179/303 (58%), Gaps = 24/303 (7%)
Query: 11 FKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLD-SEEGTPSTAIREISLMKELK---H 66
+++L +G G Y TVY+ + TG VALK+V++ +E G P + +REISL+K+L H
Sbjct: 26 YQELNIIGEGAYGTVYRARDVITGNIVALKKVRISLNENGVPMSTLREISLLKQLNASNH 85
Query: 67 DNIVRLFDVIHTENK-----LTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQL 121
NIV+L++V + + LVFE ++ DL +D K G+ ++ +L
Sbjct: 86 ANIVKLYEVCQFLERDGQLLILLVFEHVEQDLSDLIDRLPKS----GMSPPTIQRLSREL 141
Query: 122 LQGVAFCHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAP 181
L GV F H +RI+HRDLKPQNLL++++G LK+ DFGLA+ +G + +S VVTLWYRAP
Sbjct: 142 LTGVDFLHSHRIIHRDLKPQNLLVSSQGHLKIADFGLAKTYGSEMK-LTSVVVTLWYRAP 200
Query: 182 DVLMGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVT 241
+VL+ ++ Y +++DIWS CI+ EM + LFPG++++ QL IF+ G P EQ WPQ
Sbjct: 201 EVLL-AQPYNSTVDIWSAACIIFEMFNRRALFPGTSEKNQLDRIFELTGRPTEQQWPQTI 259
Query: 242 QLA-KYNPLLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPW 300
+A ++ P P P+D L + DLL+ +L + R SA L H +
Sbjct: 260 SVALEHFPQRHPKRPKDFCPHLCKYAD--------DLLNKMLSYDLHLRPSALACLEHDY 311
Query: 301 FAE 303
F +
Sbjct: 312 FQQ 314
>YKL139w [D] KOG0600 Cdc2-related protein kinase
Length = 528
Score = 202 bits (513), Expect = 6e-52
Identities = 106/295 (35%), Positives = 170/295 (56%), Gaps = 8/295 (2%)
Query: 11 FKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSE-EGTPSTAIREISLMKELKHDNI 69
+ ++ +VG GTY VYK N T VALK+++L E EG P T+IREI L++ H N+
Sbjct: 183 YLRIMQVGEGTYGKVYKAKNTNTEKLVALKKLRLQGEREGFPITSIREIKLLQSFDHPNV 242
Query: 70 VRLFDV-IHTENKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGVAFC 128
+ ++ + ++ + ++FE+ DNDL + N+ SH K+ QLL G+ +
Sbjct: 243 STIKEIMVESQKTVYMIFEYADNDLSGLLLNKEVQISHSQC-----KHLFKQLLLGMEYL 297
Query: 129 HENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGSR 188
H+N+ILHRD+K N+LI+N+G LK+ DFGLAR + +++ V+TLWYR P++L+G+
Sbjct: 298 HDNKILHRDVKGSNILIDNQGNLKITDFGLARKMNSRAD-YTNRVITLWYRPPELLLGTT 356
Query: 189 NYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQLAKYNP 248
NY T +D+W CGC+L E+ +F GSN+ EQ++ IF MGTP +WP + + +
Sbjct: 357 NYGTEVDMWGCGCLLVELFNKTAIFQGSNELEQIESIFKIMGTPTINSWPTLYDMPWFFM 416
Query: 249 LLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPWFAE 303
++P + + + + + L LL + R SA +AL +F E
Sbjct: 417 IMPQQTTKYVNNFSEKFKSVLPSSKCLQLAINLLCYDQTKRFSATEALQSDYFKE 471
>7303804 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 387
Score = 198 bits (504), Expect = 7e-51
Identities = 107/301 (35%), Positives = 176/301 (57%), Gaps = 18/301 (5%)
Query: 9 TRFKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSE-EGTPSTAIREISLMKELKHD 67
+ F++L +VG G+Y VY+ + + VALK+V++D E +G P + +REI ++K+ H+
Sbjct: 51 SEFEKLNRVGEGSYGIVYRARDTRSNEIVALKKVRMDQEKDGLPISGLREIMILKQCHHE 110
Query: 68 NIVRLFDVI--HTENKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGV 125
NIVRL +V+ + + + LV +F + DL +DN ++ + VK Q+L+ +
Sbjct: 111 NIVRLREVVVGKSLDSIFLVMDFCEQDLASVLDNMSQPFTESE-----VKCITLQVLKAL 165
Query: 126 AFCHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLM 185
+ H ++HRDLK NLL+ ++G +K+ DFGLAR F P + ++VTLWYRAP++L+
Sbjct: 166 KYLHSRFMIHRDLKVSNLLMTDKGCIKVADFGLARMFSNPPKPMTPQMVTLWYRAPELLL 225
Query: 186 GSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQLAK 245
G R + T++D+W+ GCIL E+++GKPL PG+++ QL +I D +G P E WP
Sbjct: 226 GCRTHTTAVDMWAFGCILGELLLGKPLLPGNSEIAQLDMIIDLLGAPSESIWPGFAD--- 282
Query: 246 YNPLLPPHMPRDLKQLLQNNTE---EVLDDNVVDLLHGLLQLNPDARLSAKDALNHPWFA 302
LP L Q NN ++ + +LL+ L NP R +A++ L +F
Sbjct: 283 ----LPAVQNFTLSQQPYNNLTPKFHMIGQSGRNLLNILFIYNPKTRATAEECLKSKYFV 338
Query: 303 E 303
+
Sbjct: 339 D 339
>SPBC32H8.10 [D] KOG0600 Cdc2-related protein kinase
Length = 591
Score = 197 bits (500), Expect = 2e-50
Identities = 124/316 (39%), Positives = 174/316 (54%), Gaps = 33/316 (10%)
Query: 9 TRFKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSE-EGTPSTAIREISLMKELKHD 67
T + +EK+G GT+ VYK + G ALK + + +E EG P TAIREI ++K +KH+
Sbjct: 34 TDYHLMEKLGEGTFGEVYKSQRRKDGKVYALKRILMHTEKEGFPITAIREIKILKSIKHE 93
Query: 68 NIVRLFD--VIHTENK------LTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQW 119
NI+ L D V+ + K + +V +MD+DL ++N S K E +K +
Sbjct: 94 NIIPLSDMTVVRADKKHRRRGSIYMVTPYMDHDLSGLLENP----SVKFTEPQ-IKCYMK 148
Query: 120 QLLQGVAFCHENRILHRDLKPQNLLINNRGQLKLGDFGLARAF----------GIPV--- 166
QL G + H+ ILHRDLK NLLI+N G LK+ DFGLAR G+P
Sbjct: 149 QLFAGTKYLHDQLILHRDLKAANLLIDNHGILKIADFGLARVITEESYANKNPGLPPPNR 208
Query: 167 NTFSSEVVTLWYRAPDVLMGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIF 226
++ VVT WYR+P++L+G R Y T+ID+WS GCI+AEM G+P+ GS+D +QL IF
Sbjct: 209 REYTGCVVTRWYRSPELLLGERRYTTAIDMWSVGCIMAEMYKGRPILQGSSDLDQLDKIF 268
Query: 227 DTMGTPVEQTWPQVTQLAKYNPLLP-PHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLN 285
G+P + T P +L + P PR L+ +E + L +L LN
Sbjct: 269 RLCGSPTQATMPNWEKLPGCEGVRSFPSHPRTLETAFFTFGKE-----MTSLCGAILTLN 323
Query: 286 PDARLSAKDALNHPWF 301
PD RLSA AL H +F
Sbjct: 324 PDERLSASMALEHEYF 339
>Hs4758652 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 358
Score = 196 bits (497), Expect = 5e-50
Identities = 108/298 (36%), Positives = 174/298 (58%), Gaps = 19/298 (6%)
Query: 10 RFKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGT--PSTAIREISLMKELKHD 67
+++++ K+G G+Y V+K N+ TG VA+K+ L+SE+ A+REI ++K+LKH
Sbjct: 4 KYEKIGKIGEGSYGVVFKCRNRDTGQIVAIKKF-LESEDDPVIKKIALREIRMLKQLKHP 62
Query: 68 NIVRLFDVIHTENKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGVAF 127
N+V L +V + +L LVFE+ D+ + +D +G + LVK WQ LQ V F
Sbjct: 63 NLVNLLEVFRRKRRLHLVFEYCDHTVLHELDRYQRG-----VPEHLVKSITWQTLQAVNF 117
Query: 128 CHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGS 187
CH++ +HRD+KP+N+LI +KL DFG AR P + ++ V T WYR+P++L+G
Sbjct: 118 CHKHNCIHRDVKPENILITKHSVIKLCDFGFARLLTGPSDYYTDYVATRWYRSPELLVGD 177
Query: 188 RNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQLAKYN 247
Y +D+W+ GC+ AE++ G PL+PG +D +QL LI T+G + + QV +Y
Sbjct: 178 TQYGPPVDVWAIGCVFAELLSGVPLWPGKSDVDQLYLIRKTLGDLIPR-HQQVFSTNQYF 236
Query: 248 PLLPPHMPRDLKQLLQNNTEEVLDDNV----VDLLHGLLQLNPDARLSAKDALNHPWF 301
+ P D++ L E+ N+ + LL G L ++P RL+ + L+HP+F
Sbjct: 237 SGVKIPDPEDMEPL------ELKFPNISYPALGLLKGCLHMDPTERLTCEQLLHHPYF 288
>Hs4505569 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 493
Score = 195 bits (495), Expect = 8e-50
Identities = 105/298 (35%), Positives = 173/298 (57%), Gaps = 19/298 (6%)
Query: 10 RFKQLEKVGNGTYATVYKGLNKTTGVYVALKE-VKLDSEEGTPSTAIREISLMKELKHDN 68
+++ L VG G+Y V K NK TG VA+K+ ++ D ++ A+REI L+K+L+H+N
Sbjct: 3 KYENLGLVGEGSYGMVMKCRNKDTGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRHEN 62
Query: 69 IVRLFDVIHTENKLTLVFEFMDN----DLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQG 124
+V L +V + + LVFEF+D+ DL+ F + GL+ +V+ + +Q++ G
Sbjct: 63 LVNLLEVCKKKKRWYLVFEFVDHTILDDLELFPN---------GLDYQVVQKYLFQIING 113
Query: 125 VAFCHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVL 184
+ FCH + I+HRD+KP+N+L++ G +KL DFG AR P ++ V T WYRAP++L
Sbjct: 114 IGFCHSHNIIHRDIKPENILVSQSGVVKLCDFGFARTLAAPGEVYTDYVATRWYRAPELL 173
Query: 185 MGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQLA 244
+G Y ++D+W+ GC++ EM MG+PLFPG +D +QL I +G + P+ +L
Sbjct: 174 VGDVKYGKAVDVWAIGCLVTEMFMGEPLFPGDSDIDQLYHIMMCLGNLI----PRHQELF 229
Query: 245 KYNPLLP-PHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPWF 301
NP+ +P ++ L + V+DL L ++PD R + L+H +F
Sbjct: 230 NKNPVFAGVRLPEIKEREPLERRYPKLSEVVIDLAKKCLHIDPDKRPFCAELLHHDFF 287
>At5g39420 [D] KOG0600 Cdc2-related protein kinase
Length = 576
Score = 194 bits (494), Expect = 1e-49
Identities = 113/291 (38%), Positives = 170/291 (57%), Gaps = 14/291 (4%)
Query: 11 FKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDS-EEGTPSTAIREISLMKELKHDNI 69
F++LEK+G GTY++V++ TG VALK+VK D+ + + REI ++++L H NI
Sbjct: 105 FQKLEKIGQGTYSSVFRAREVETGKMVALKKVKFDNLQPESIRFMAREILILRKLNHPNI 164
Query: 70 VRLFDVI--HTENKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGVAF 127
++L ++ + + LVFE+M++DL N + + +K + QLL G+
Sbjct: 165 MKLEGIVTSRASSSIYLVFEYMEHDLAGLSSNPDIRFTEPQ-----IKCYMKQLLWGLEH 219
Query: 128 CHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIP-VNTFSSEVVTLWYRAPDVLMG 186
CH ++HRD+K N+L+NN+G LKLGDFGLA N +S VVTLWYRAP++LMG
Sbjct: 220 CHMRGVIHRDIKASNILVNNKGVLKLGDFGLANVVTPSNKNQLTSRVVTLWYRAPELLMG 279
Query: 187 SRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQLAKY 246
S +Y S+D+WS GC+ AE++MGKP+ G + EQL I+ G+P + W + T+L
Sbjct: 280 STSYGVSVDLWSVGCVFAEILMGKPILKGRTEIEQLHKIYKLCGSPQDSFWKR-TKLPHA 338
Query: 247 NPLLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALN 297
P H + L+ ++ L V LL LL + PD R +A ALN
Sbjct: 339 TSFKPQH---TYEATLRERCKD-LSATGVYLLETLLSMEPDKRGTASSALN 385
>At5g44290 [D] KOG0600 Cdc2-related protein kinase
Length = 644
Score = 193 bits (491), Expect = 2e-49
Identities = 121/305 (39%), Positives = 173/305 (56%), Gaps = 24/305 (7%)
Query: 6 RYETRFKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLD-SEEGTPSTAIREISLMKEL 64
R + F++LEK+G GTY++VYK + T VALK V+ D S+ + REI +M+ L
Sbjct: 132 RRASTFEKLEKIGQGTYSSVYKARDLTNNKIVALKRVRFDLSDLESVKFMAREIIVMRRL 191
Query: 65 KHDNIVRLFDVI--HTENKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMD--LVKYFQWQ 120
H N+++L +I + L LVFE+MD+DL S G++ VK + Q
Sbjct: 192 DHPNVLKLEGLITASVSSSLYLVFEYMDHDLVGLA-------SIPGIKFSEPQVKCYMQQ 244
Query: 121 LLQGVAFCHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNT--FSSEVVTLWY 178
LL G+ CH +LHRD+K NLLI++ G LK+ DFGLA F P N +S VVTLWY
Sbjct: 245 LLSGLHHCHSRGVLHRDIKGSNLLIDSNGVLKIADFGLATFFD-PQNCVPLTSRVVTLWY 303
Query: 179 RAPDVLMGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWP 238
R P++L+G+ +Y +D+WS GCIL E+ GKP+ G + EQL IF G+P E W
Sbjct: 304 RPPELLLGACHYGVGVDLWSTGCILGELYSGKPILAGKTEVEQLHKIFKLCGSPTEDYWR 363
Query: 239 --QVTQLAKYNPLLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDAL 296
++ A + P LP R + ++ ++ L NV+ LL LL ++PD R SA AL
Sbjct: 364 KLKLPPSAAFRPALP--YGRRVAEMFKD-----LPTNVLSLLEALLSIDPDRRGSAARAL 416
Query: 297 NHPWF 301
+F
Sbjct: 417 ESEYF 421
>At5g50860 [D] KOG0600 Cdc2-related protein kinase
Length = 580
Score = 191 bits (485), Expect = 1e-48
Identities = 116/303 (38%), Positives = 173/303 (56%), Gaps = 20/303 (6%)
Query: 6 RYETRFKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSEEG-TPSTAIREISLMKEL 64
R T +++LEK+G GTY+ VYK + +G VALK+V+ D+ E + REI +++ L
Sbjct: 109 RRATTYEKLEKIGQGTYSNVYKAKDLLSGKIVALKKVRFDNLEAESVKFMAREILVLRRL 168
Query: 65 KHDNIVRLFDVI--HTENKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDL--VKYFQWQ 120
H N+++L ++ L LVFE+M++DL + +GL+ DL VK F Q
Sbjct: 169 NHPNVIKLQGLVTSRVSCSLYLVFEYMEHDLSGLA-------ATQGLKFDLPQVKCFMKQ 221
Query: 121 LLQGVAFCHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVN-TFSSEVVTLWYR 179
LL G+ CH +LHRD+K NLLI+N G LK+ DFGLA + T +S VVTLWYR
Sbjct: 222 LLSGLEHCHSRGVLHRDIKGSNLLIDNDGILKIADFGLATFYDPKQKQTMTSRVVTLWYR 281
Query: 180 APDVLMGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQ 239
P++L+G+ +Y T +D+WS GCI+AE++ GKP+ PG + EQL IF G+P + W +
Sbjct: 282 PPELLLGATSYGTGVDLWSAGCIMAELLAGKPVMPGRTEVEQLHKIFKLCGSPSDSYWKK 341
Query: 240 VTQLAKYNPLLPPH-MPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNH 298
+L P H R + + T + V L+ LL ++P R ++ ALN
Sbjct: 342 Y-RLPNATLFKPQHPYKRCVAEAFNGFT-----PSSVHLVETLLTIDPADRGTSTSALNS 395
Query: 299 PWF 301
+F
Sbjct: 396 EFF 398
>SPAC23H4.17c [K] KOG0666 Cyclin C-dependent kinase CDK8
Length = 352
Score = 190 bits (483), Expect = 2e-48
Identities = 109/317 (34%), Positives = 177/317 (55%), Gaps = 28/317 (8%)
Query: 11 FKQLEKVGNGTYATVYKGL--NKTTGVYVALKEVKLDSEE--------GTPSTAIREISL 60
+K + + +GTY VYK + N A+K+ K +S++ G +AIRE+ L
Sbjct: 5 YKIIGFISSGTYGKVYKAVSSNSNDKRLFAIKKFKAESKQVSSNAQQTGVSQSAIREMML 64
Query: 61 MKELKHDNIVRLFDVIHTENKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQ 120
+E++H+NIV L V+ + +++VFE+ ++DL + + ++ + + + ++K WQ
Sbjct: 65 CREIQHENIVSLVQVLLKDGTISMVFEYAEHDLLQIIHFHSRSRTRQ-IPPSILKSILWQ 123
Query: 121 LLQGVAFCHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSE---VVTLW 177
++ GVA+ HEN I+HRDLKP N++I G++K+GD GL R P+ F S VVT+W
Sbjct: 124 IINGVAYLHENWIMHRDLKPANIMITATGKVKIGDLGLGRLIRDPILPFYSSDRVVVTIW 183
Query: 178 YRAPDVLMGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSN-----------DEEQLKLIF 226
YRAP++L+G+ +Y +ID+W+ GCI EM+ PLF G Q+ I
Sbjct: 184 YRAPELLLGAHDYTPAIDVWAIGCIYGEMLALSPLFKGDEIKMEDKKVVPFQSTQMLRIM 243
Query: 227 DTMGTPVEQTWPQVTQLAKYNPLLPPHMPRDLKQLLQN--NTEEVLDDNVVDLLHGLLQL 284
+ +GTP E+ WP + +Y L + R LL T + D +DLL +LQ
Sbjct: 244 ELLGTPTEERWPGLKNYPEYYQLSSFEV-RYWNNLLPQWYQTVKNRDPQGLDLLMKMLQY 302
Query: 285 NPDARLSAKDALNHPWF 301
+P +R++AK AL H +F
Sbjct: 303 DPKSRITAKQALEHVFF 319
>Hs7662388 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 632
Score = 189 bits (480), Expect = 4e-48
Identities = 105/293 (35%), Positives = 168/293 (56%), Gaps = 12/293 (4%)
Query: 10 RFKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPSTAIREISLMKELKHDNI 69
R+ + ++G+GTY +V G + +G +A+K++K +RE+ +K+L H N+
Sbjct: 3 RYTTIRQLGDGTYGSVLLGRSIESGELIAIKKMKRKFYSWEECMNLREVKSLKKLNHANV 62
Query: 70 VRLFDVIHTENKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGVAFCH 129
V+L +VI + L +FE+M +L + + RNK ++ +Q+LQG+AF H
Sbjct: 63 VKLKEVIRENDHLYFIFEYMKENLYQLIKERNKLFPESA-----IRNIMYQILQGLAFIH 117
Query: 130 ENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGSRN 189
++ HRDLKP+NLL +K+ DFGLAR ++ V T WYRAP+VL+ S N
Sbjct: 118 KHGFFHRDLKPENLLCMGPELVKIADFGLAREIRSKP-PYTDYVSTRWYRAPEVLLRSTN 176
Query: 190 YCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQLAK-YNP 248
Y + ID+W+ GCI+AE+ +PLFPG+++ + + I +GTP + WP+ QL+ N
Sbjct: 177 YSSPIDVWAVGCIMAEVYTLRPLFPGASEIDTIFKICQVLGTPKKTDWPEGYQLSSAMNF 236
Query: 249 LLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPWF 301
P +P +LK L+ N + E V LL +LQ +P R +A AL +P+F
Sbjct: 237 RWPQCVPNNLKTLIPNASSE-----AVQLLRDMLQWDPKKRPTASQALRYPYF 284
>At1g33770 [D] KOG0600 Cdc2-related protein kinase
Length = 614
Score = 189 bits (479), Expect = 6e-48
Identities = 115/299 (38%), Positives = 172/299 (57%), Gaps = 22/299 (7%)
Query: 11 FKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKL-DSEEGTPSTAIREISLMKELKHDNI 69
F++L+K+G GTY+ VYK + TG VA+K+V+ + + + REI+++++L H N+
Sbjct: 141 FEKLDKIGQGTYSIVYKARDLETGKIVAMKKVRFANMDPESVRFMAREINILRKLDHPNV 200
Query: 70 VRLFDVIHTE--NKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMD--LVKYFQWQLLQGV 125
++L ++ ++ L LVFE+M++DL G++ +K F QLL G+
Sbjct: 201 MKLQCLVTSKLSGSLHLVFEYMEHDLSGLA-------LRPGVKFTEPQIKCFMKQLLCGL 253
Query: 126 AFCHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNT-FSSEVVTLWYRAPDVL 184
CH ILHRD+K NLL+NN G LK+GDFGLA + + +S VVTLWYRAP++L
Sbjct: 254 EHCHSRGILHRDIKGSNLLVNNDGVLKIGDFGLASFYKPDQDQPLTSRVVTLWYRAPELL 313
Query: 185 MGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTW--PQVTQ 242
+GS Y +ID+WS GCILAE+ + KP+ PG + EQ+ IF G+P E+ W + Q
Sbjct: 314 LGSTEYGPAIDLWSVGCILAELFVCKPIMPGRTEVEQMHKIFKLCGSPSEEFWNTTKFPQ 373
Query: 243 LAKYNPLLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPWF 301
Y P P R L + +N L + +DLL LL + P+ R SA L +F
Sbjct: 374 ATSYKPQHP--YKRVLLETFKN-----LSSSSLDLLDKLLSVEPEKRCSASSTLLSEFF 425
>Hs16306492 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 240
Score = 188 bits (478), Expect = 7e-48
Identities = 116/297 (39%), Positives = 158/297 (53%), Gaps = 66/297 (22%)
Query: 11 FKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSEE-GTPSTAIREISLMKELKHDNI 69
+ ++EK+G GTY VYKG +KTTG VA+K+++L+SEE G PSTAIREISL+KEL+H NI
Sbjct: 4 YTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPNI 63
Query: 70 VRLFDVIHTENKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGVAFCH 129
V L DV+ +++L L+FEF L MDL KY
Sbjct: 64 VSLQDVLMQDSRLYLIFEF--------------------LSMDLKKYLD----------- 92
Query: 130 ENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGSRN 189
+ P + D L + VVTLWYR+P+VL+GS
Sbjct: 93 -------SIPPGQYM----------DSSLVK------------VVTLWYRSPEVLLGSAR 123
Query: 190 YCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQLAKYNPL 249
Y T +DIWS G I AE+ KPLF G ++ +QL IF +GTP + WP+V L Y
Sbjct: 124 YSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNT 183
Query: 250 LPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPWFAEYNH 306
P P L ++N LD+N +DLL +L +P R+S K ALNHP+F + ++
Sbjct: 184 FPKWKPGSLASHVKN-----LDENGLDLLSKMLIYDPAKRISGKMALNHPYFNDLDN 235
>Hs11496279 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 623
Score = 188 bits (478), Expect = 7e-48
Identities = 103/293 (35%), Positives = 168/293 (57%), Gaps = 12/293 (4%)
Query: 10 RFKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPSTAIREISLMKELKHDNI 69
R+ + ++G+GTY +V G + +G VA+K +K +RE+ +K+L H N+
Sbjct: 3 RYTTMRQLGDGTYGSVLMGKSNESGELVAIKRMKRKFYSWDECMNLREVKSLKKLNHANV 62
Query: 70 VRLFDVIHTENKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGVAFCH 129
++L +VI + L +FE+M +L + M +RNK +++ +Q+LQG+AF H
Sbjct: 63 IKLKEVIRENDHLYFIFEYMKENLYQLMKDRNKL-----FPESVIRNIMYQILQGLAFIH 117
Query: 130 ENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGSRN 189
++ HRD+KP+NLL +K+ DFGLAR ++ V T WYRAP+VL+ S
Sbjct: 118 KHGFFHRDMKPENLLCMGPELVKIADFGLARELRSQP-PYTDYVSTRWYRAPEVLLRSSV 176
Query: 190 YCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQLA-KYNP 248
Y + ID+W+ G I+AE+ M +PLFPG+++ +++ I +GTP + WP+ QLA N
Sbjct: 177 YSSPIDVWAVGSIMAELYMLRPLFPGTSEVDEIFKICQVLGTPKKSDWPEGYQLASSMNF 236
Query: 249 LLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPWF 301
P +P +LK L+ N + E + L+ +L +P R +A AL HP+F
Sbjct: 237 RFPQCVPINLKTLIPNASNE-----AIQLMTEMLNWDPKKRPTASQALKHPYF 284
>ECU02g1450 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 308
Score = 188 bits (478), Expect = 7e-48
Identities = 108/300 (36%), Positives = 164/300 (54%), Gaps = 28/300 (9%)
Query: 16 KVGNGTYATVYKGLN-------------KTTGVYVALKEVKLDS-EEGTPSTAIREISLM 61
++G GTYA +Y G + V VA+K++K +G +AIREI +
Sbjct: 9 RLGEGTYAVIYLGYRALPQDKPLVSSGTRIEDVPVAIKKIKPTKYTQGHEISAIREIKSL 68
Query: 62 KELKHDNIVRLFDVIHTENKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQL 121
K + +VRL D + + +V E+++ +L+ + N S K + +K + +
Sbjct: 69 KRIDSKYVVRLIDTFVYDKCVHIVLEYVETNLENVIRN-----SDKIIMPGDIKAWILMV 123
Query: 122 LQGVAFCHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAP 181
L+GV CH I+HRD+KP N+LI + G +KL DFGL R G N + + VT WYRAP
Sbjct: 124 LRGVYECHRLFIIHRDIKPNNILITSEGMVKLADFGLTRGIG---NRMTPQAVTRWYRAP 180
Query: 182 DVLMGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVT 241
++LMGSR+Y + +D+WS GC+ AE+ + PLF G D +QL +IF +GTPVE+ WP V+
Sbjct: 181 ELLMGSRDYGSPVDMWSVGCVFAELFLRVPLFAGDTDIQQLDMIFRALGTPVEREWPGVS 240
Query: 242 QLAKYNPLLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPWF 301
L ++ + + N + +DLL LL LNP R+S DA+ HP+F
Sbjct: 241 TLPEFLDF------QQYPKASLNGLFSAASSDALDLLEKLLTLNPCNRISCDDAIKHPYF 294
>7297578 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 822
Score = 188 bits (477), Expect = 1e-47
Identities = 110/292 (37%), Positives = 168/292 (56%), Gaps = 10/292 (3%)
Query: 10 RFKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPSTAIREISLMKELKHDNI 69
R+ L ++G+GTY TV G K TG VA+K +K + +RE+ +K+L H NI
Sbjct: 3 RYITLTQLGDGTYGTVVLGQRKDTGEKVAIKRMKRKYYSWEEAMNLREVKSLKKLSHPNI 62
Query: 70 VRLFDVIHTENKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGVAFCH 129
V+L +VI + L VFE+M +L + + +R+ +H L +K +Q+L G+AF H
Sbjct: 63 VKLKEVIRENDTLYFVFEYMKENLYQMIKDRD---TH--LPEPELKSILFQVLTGLAFMH 117
Query: 130 ENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGSRN 189
+ HRDLKP+NLL + +K+ DFGLAR F+ V T WYRAP+VL+ S N
Sbjct: 118 RHGFFHRDLKPENLLCSGPDLIKIADFGLAREIRSRP-PFTDYVSTRWYRAPEVLLHSTN 176
Query: 190 YCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQLAKYNPL 249
Y ++ID+W+ GCI+AE+ +PLFPGS++ +QL I +GTP + WP +LA
Sbjct: 177 YGSTIDLWAMGCIMAELYTFRPLFPGSSEVDQLFKICSVLGTPDKDDWPDGYRLASMIHF 236
Query: 250 LPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPWF 301
P D ++ ++ N +DLL +L +PD R +A+ +L +P+F
Sbjct: 237 RYP----DCIKVPLSSVVSRCSQNGLDLLEDMLAYDPDKRPTAQQSLKYPYF 284
>YPR161c [D] KOG0600 Cdc2-related protein kinase
Length = 657
Score = 187 bits (476), Expect = 1e-47
Identities = 110/323 (34%), Positives = 175/323 (54%), Gaps = 36/323 (11%)
Query: 7 YETRFKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGT-PSTAIREISLMKELK 65
++ +++ EK+G GT+ VYKG++ T VA+K++ + E+ P TA REI+++K L
Sbjct: 56 FQNHYREDEKLGQGTFGEVYKGIHLETQRQVAMKKIIVSVEKDLFPITAQREITILKRLN 115
Query: 66 HDNIVRLFDVIHTEN-------------KLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMD 112
H NI++L ++++ + ++ +M DL + N LEM
Sbjct: 116 HKNIIKLIEMVYDHSPDITNAASSNLHKSFYMILPYMVADLSGVLHN-----PRINLEMC 170
Query: 113 LVKYFQWQLLQGVAFCHENRILHRDLKPQNLLINNRGQLKLGDFGLARAF-GIPVNT--- 168
+K Q+L+G+ + H + +HRD+K N+LI++ G LKL DFGLAR + G P N
Sbjct: 171 DIKNMMLQILEGLNYIHCAKFMHRDIKTANILIDHNGVLKLADFGLARLYYGCPPNLKYP 230
Query: 169 --------FSSEVVTLWYRAPDVLMGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEE 220
++S VVT WYRAP++++G + Y T++DIW GC+ AE KP+ G D +
Sbjct: 231 GGAGSGAKYTSVVVTRWYRAPELVLGDKQYTTAVDIWGVGCVFAEFFEKKPILQGKTDID 290
Query: 221 QLKLIFDTMGTPVEQTWPQVTQLAKYNPLLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHG 280
Q +IF +GTP E+ W +A+Y P + K L+ + L + +D L
Sbjct: 291 QGHVIFKLLGTPTEEDW----AVARYLP-GAELTTTNYKPTLRERFGKYLSETGLDFLGQ 345
Query: 281 LLQLNPDARLSAKDALNHPWFAE 303
LL L+P RL+A A +HPWF E
Sbjct: 346 LLALDPYKRLTAMSAKHHPWFKE 368
>CE26988 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 308
Score = 187 bits (475), Expect = 2e-47
Identities = 108/296 (36%), Positives = 162/296 (54%), Gaps = 36/296 (12%)
Query: 10 RFKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSEE----GTPSTAIREISLMKELK 65
R+ ++ +G G +A VY + +G VA+K++KL S E G TAIREI L+KE+
Sbjct: 4 RYDTIKHLGEGQFANVYLAQDLESGECVAIKKIKLGSREEAKDGINRTAIREIKLLKEIH 63
Query: 66 HDNIVRLFDVIHTENKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGV 125
HDNI+ L DVI + LVF+FMD DL+ + ++ L +K Q+L G+
Sbjct: 64 HDNIIGLRDVIGHRTSIQLVFDFMDTDLEHVIKDKEII-----LMPAHIKNITMQMLLGL 118
Query: 126 AFCHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLM 185
F H + ILHRDLKP NLL+N G+ VVT WYRAP++L
Sbjct: 119 EFLHVHWILHRDLKPNNLLMNKMGR----------------------VVTRWYRAPELLF 156
Query: 186 GSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQLAK 245
G+R+Y IDIWS GCI+AE+++ P+FPG +D +QL IF+ +G P +TWP +T++
Sbjct: 157 GARSYGVGIDIWSVGCIIAELLLRNPIFPGESDIDQLVKIFNILGCPTPETWPNMTEMNS 216
Query: 246 YNPLLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPWF 301
Y + P + + N +++DL+ G+ +P RL+ +L +F
Sbjct: 217 YVIIKP-----QTEYMALNYYFSAAPQDLLDLMAGMWTFDPIKRLTCTQSLQMEYF 267
>At3g05050 [D] KOG0600 Cdc2-related protein kinase
Length = 593
Score = 187 bits (475), Expect = 2e-47
Identities = 112/307 (36%), Positives = 172/307 (55%), Gaps = 21/307 (6%)
Query: 4 LLRYETRFKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLD-SEEGTPSTAIREISLMK 62
L R F++++K+G+GTY+ VYK + TG VALK+V+ D +E + REI +++
Sbjct: 131 LPRKADSFEKIDKIGSGTYSNVYKAKDSLTGNIVALKKVRCDVNERESLKFMAREILILR 190
Query: 63 ELKHDNIVRLFDVIHTE--NKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQ 120
L H N+++L ++ + + L LVF +MD+DL + VK + Q
Sbjct: 191 RLDHPNVIKLEGLVTSRMSSSLYLVFRYMDHDLAGLA-----ASPEIKFTEQQVKCYMKQ 245
Query: 121 LLQGVAFCHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNT-FSSEVVTLWYR 179
LL G+ CH +LHRD+K NLLI++ G L++GDFGLA F ++ VVTLWYR
Sbjct: 246 LLSGLEHCHNRGVLHRDIKGSNLLIDDGGVLRIGDFGLATFFDASKRQEMTNRVVTLWYR 305
Query: 180 APDVLMGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTW-- 237
+P++L G Y +D+WS GCILAE++ G+ + PG N+ EQL I+ G+P E+ W
Sbjct: 306 SPELLHGVVEYSVGVDLWSAGCILAELLAGRAIMPGRNEVEQLHRIYKLCGSPSEEYWKK 365
Query: 238 ---PQVTQLAKYNPLLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKD 294
P + A + PL P R ++++ ++ + E L LL LL L+P R +A D
Sbjct: 366 IRLPSTHKHAHHKPL--PQYKRRIREVYKDFSPEAL-----SLLDTLLALDPAERQTATD 418
Query: 295 ALNHPWF 301
L +F
Sbjct: 419 VLMSDFF 425
>At1g53050 [D] KOG0600 Cdc2-related protein kinase
Length = 694
Score = 187 bits (474), Expect = 2e-47
Identities = 116/299 (38%), Positives = 168/299 (55%), Gaps = 20/299 (6%)
Query: 11 FKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDS-EEGTPSTAIREISLMKELKHDNI 69
F++L+K+G GTY+ VY+ + VALK+V+ D+ E + REI +++ L H NI
Sbjct: 134 FEKLDKIGQGTYSNVYRARDLDQKKIVALKKVRFDNLEPESVRFMAREIQILRRLDHPNI 193
Query: 70 VRLFDVIHTENK--LTLVFEFMDNDLKKFMDNRNKGNSHKGLEMD--LVKYFQWQLLQGV 125
++L ++ + L LVFE+M++DL SH ++ VK + QLL G+
Sbjct: 194 IKLEGLVTSRMSCSLYLVFEYMEHDLAGLA-------SHPAIKFSESQVKCYLQQLLHGL 246
Query: 126 AFCHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNT--FSSEVVTLWYRAPDV 183
CH +LHRD+K NLLI+N G LK+ DFGLA F P T +S VVTLWYR P++
Sbjct: 247 DHCHSRGVLHRDIKGSNLLIDNSGVLKIADFGLASFFD-PRQTQPLTSRVVTLWYRPPEL 305
Query: 184 LMGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQL 243
L+G+ Y ++D+WS GCILAE+ GKP+ PG + EQL IF G+P E W V
Sbjct: 306 LLGATRYGAAVDLWSAGCILAELYAGKPIMPGRTEVEQLHKIFKLCGSPTEDYW--VKSR 363
Query: 244 AKYNPLLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPWFA 302
+ + P P K+L+ +E + LL LL +NPD R +A AL +F+
Sbjct: 364 LPHATIFKPTQP--YKRLVGETFKE-FPQPALALLETLLSVNPDDRGTATAALKSEFFS 419
>At1g71530 [D] KOG0600 Cdc2-related protein kinase
Length = 655
Score = 186 bits (472), Expect = 4e-47
Identities = 109/297 (36%), Positives = 168/297 (55%), Gaps = 18/297 (6%)
Query: 11 FKQLEKVGNGTYATVYKGLNKTTGVYVALKEVK-LDSEEGTPSTAIREISLMKELKHDNI 69
F++L+K+G GTY++VYK + TG VA+K+V+ ++ + + REI ++++L H N+
Sbjct: 147 FEKLDKIGQGTYSSVYKARDLETGKIVAMKKVRFVNMDPESVRFMAREILILRKLDHPNV 206
Query: 70 VRLFDVIHTE--NKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMD--LVKYFQWQLLQGV 125
++L ++ + L LVFE+M++DL + G++ +K + QL +G+
Sbjct: 207 MKLEGLVTSRLSGSLYLVFEYMEHDLAGLA-------ATPGIKFSEPQIKCYMQQLFRGL 259
Query: 126 AFCHENRILHRDLKPQNLLINNRGQLKLGDFGLARAF-GIPVNTFSSEVVTLWYRAPDVL 184
CH ILHRD+K NLLINN G LK+GDFGLA + G +S VVTLWYRAP++L
Sbjct: 260 EHCHRRGILHRDIKGSNLLINNEGVLKIGDFGLANFYRGDGDLQLTSRVVTLWYRAPELL 319
Query: 185 MGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQLA 244
+G+ Y +ID+WS GCIL E+ GKP+ PG + EQ+ IF G+P E W + T
Sbjct: 320 LGATEYGPAIDLWSAGCILTELFAGKPIMPGRTEVEQMHKIFKLCGSPSEDYWRRATL-- 377
Query: 245 KYNPLLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPWF 301
PL P + + T + + L++ LL + P+ R SA L +F
Sbjct: 378 ---PLATSFKPSHPYKPVLAETFNHFPSSALMLINKLLAIEPEKRGSAASTLRSEFF 431
>Hs7705551 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 632
Score = 186 bits (471), Expect = 5e-47
Identities = 105/293 (35%), Positives = 166/293 (55%), Gaps = 12/293 (4%)
Query: 10 RFKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPSTAIREISLMKELKHDNI 69
R+ + ++G+GTY +V G + +G +A+K++K RE+ +K+L H N+
Sbjct: 3 RYTTIRQLGDGTYGSVLLGRSIESGELIAIKKMKRKFYSWEECMNQREVKSLKKLNHANV 62
Query: 70 VRLFDVIHTENKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGVAFCH 129
V+L +VI + L +FE+M +L + + RNK ++ +Q+LQG+AF H
Sbjct: 63 VKLKEVIRENDHLYFIFEYMKENLYQLIKERNKLFPESA-----IRNIMYQILQGLAFIH 117
Query: 130 ENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGSRN 189
+ HRDLKP+NLL +K+ DFGLAR ++ V T WYRAP+VL+ S N
Sbjct: 118 KLGFFHRDLKPENLLCMGPELVKIADFGLAREIRSKP-PYTDYVSTRWYRAPEVLLRSTN 176
Query: 190 YCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQLAK-YNP 248
Y + ID+W+ GCI+AE+ +PLFPG+++ + + I +GTP + WP+ QL+ N
Sbjct: 177 YSSPIDVWAVGCIMAEVYTLRPLFPGASEIDTIFKICQVLGTPKKTDWPEGYQLSSAMNF 236
Query: 249 LLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPWF 301
P +P +LK L+ N + E V LL +LQ +P R +A AL +P+F
Sbjct: 237 RWPQCVPNNLKTLIPNASSE-----AVQLLRDMLQWDPKKRPTASQALRYPYF 284
>At1g03740 [D] KOG0600 Cdc2-related protein kinase
Length = 542
Score = 186 bits (471), Expect = 5e-47
Identities = 115/305 (37%), Positives = 173/305 (56%), Gaps = 24/305 (7%)
Query: 6 RYETRFKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLD-SEEGTPSTAIREISLMKEL 64
R F++LEK+G GTY++VY+ + VALK+V+ D ++ + REI +M+ L
Sbjct: 208 RRANTFEKLEKIGQGTYSSVYRARDLLHNKIVALKKVRFDLNDMESVKFMAREIIVMRRL 267
Query: 65 KHDNIVRLFDVIHT--ENKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMD--LVKYFQWQ 120
H N+++L +I + L LVFE+MD+DL +S G++ VK + Q
Sbjct: 268 DHPNVLKLEGLITAPVSSSLYLVFEYMDHDLLGL-------SSLPGVKFTEPQVKCYMRQ 320
Query: 121 LLQGVAFCHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFS--SEVVTLWY 178
LL G+ CH +LHRD+K NLLI+++G LK+ DFGLA F P + S S VVTLWY
Sbjct: 321 LLSGLEHCHSRGVLHRDIKGSNLLIDSKGVLKIADFGLATFFD-PAKSVSLTSHVVTLWY 379
Query: 179 RAPDVLMGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTW- 237
R P++L+G+ +Y +D+WS GCIL E+ GKP+ PG + EQL IF G+P E W
Sbjct: 380 RPPELLLGASHYGVGVDLWSTGCILGELYAGKPILPGKTEVEQLHKIFKLCGSPTENYWR 439
Query: 238 -PQVTQLAKYNPLLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDAL 296
++ A + +P R + ++ ++ +V+ LL LL ++PD R SA AL
Sbjct: 440 KQKLPSSAGFKTAIP--YRRKVSEMFKD-----FPASVLSLLETLLSIDPDHRSSADRAL 492
Query: 297 NHPWF 301
+F
Sbjct: 493 ESEYF 497
>At4g10010 [D] KOG0600 Cdc2-related protein kinase
Length = 649
Score = 185 bits (469), Expect = 8e-47
Identities = 110/303 (36%), Positives = 175/303 (57%), Gaps = 30/303 (9%)
Query: 11 FKQLEKVGNGTYATVYKGLNKTTGVYVALKEVK-LDSEEGTPSTAIREISLMKELKHDNI 69
F++L+K+G GTY++VY+ + TG VA+K+V+ ++ + + REI+++++L H N+
Sbjct: 156 FEKLDKIGQGTYSSVYRARDLETGKMVAMKKVRFVNMDPESVRFMAREINILRKLDHPNV 215
Query: 70 VRLFDVIHTE--NKLTLVFEFMDNDLK--------KFMDNRNKGNSHKGLEMDLVKYFQW 119
++L ++ ++ L LVFE+M++DL KF +++ +K +
Sbjct: 216 MKLECLVTSKLSGSLYLVFEYMEHDLSGLALRPGVKFTESQ-------------IKCYMK 262
Query: 120 QLLQGVAFCHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNT-FSSEVVTLWY 178
QLL G+ CH ILHRD+K NLL+NN G LK+GDFGLA + + +S VVTLWY
Sbjct: 263 QLLSGLEHCHSRGILHRDIKGPNLLVNNDGVLKIGDFGLANIYHPEQDQPLTSRVVTLWY 322
Query: 179 RAPDVLMGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWP 238
RAP++L+G+ Y ID+WS GCIL E+ +GKP+ PG + EQ+ IF G+P + W
Sbjct: 323 RAPELLLGATEYGPGIDLWSVGCILTELFLGKPIMPGRTEVEQMHKIFKFCGSPSDDYW- 381
Query: 239 QVTQLAKYNPLLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNH 298
Q T+L PL P+ + + T + L + + L+ LL L P R +A L+
Sbjct: 382 QKTKL----PLATSFKPQQPYKRVLLETFKNLPPSALALVDKLLSLEPAKRGTASSTLSS 437
Query: 299 PWF 301
+F
Sbjct: 438 KFF 440
>At1g09600 [D] KOG0600 Cdc2-related protein kinase
Length = 714
Score = 184 bits (468), Expect = 1e-46
Identities = 108/295 (36%), Positives = 169/295 (56%), Gaps = 14/295 (4%)
Query: 11 FKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKL-DSEEGTPSTAIREISLMKELKHDNI 69
F++LEK+G GTY++VYK + T VALK+V+ + + + REI +++ L H N+
Sbjct: 163 FEKLEKIGQGTYSSVYKARDLETNQLVALKKVRFANMDPDSVRFMAREIIILRRLDHPNV 222
Query: 70 VRLFDVI--HTENKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGVAF 127
++L +I + L+FE+M++DL S +K + QLL G+
Sbjct: 223 MKLEGLITSRVSGSMYLIFEYMEHDLAGLASTPGINFSEAQ-----IKCYMKQLLHGLEH 277
Query: 128 CHENRILHRDLKPQNLLINNRGQLKLGDFGLARAF-GIPVNTFSSEVVTLWYRAPDVLMG 186
CH +LHRD+K NLL+++ LK+GDFGLA + G +S VVTLWYR P++L+G
Sbjct: 278 CHSRGVLHRDIKGSNLLLDHNNNLKIGDFGLANFYQGHQKQPLTSRVVTLWYRPPELLLG 337
Query: 187 SRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQLAKY 246
S +Y ++D+WS GCILAE+ GKP+ PG + EQL IF G+P E+ W ++++L +
Sbjct: 338 STDYGVTVDLWSTGCILAELFTGKPIMPGRTEVEQLHKIFKLCGSPSEEYW-KISKL-PH 395
Query: 247 NPLLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPWF 301
+ P P K+ + T + L + + L+ LL + PDAR + AL +F
Sbjct: 396 ATIFKPQQP--YKRCVA-ETFKSLPSSALALVEVLLAVEPDARGTTASALESEFF 447
>At5g63610 [K] KOG0666 Cyclin C-dependent kinase CDK8
Length = 470
Score = 184 bits (467), Expect = 1e-46
Identities = 111/319 (34%), Positives = 173/319 (53%), Gaps = 36/319 (11%)
Query: 10 RFKQLEKVGNGTYATVYKGLNKTTGVY-VALKEVKLDSE-EGTPSTAIREISLMKELKHD 67
++ + K+G GTY V+ KT +A+K+ K + +G TAIREI L++E+ H+
Sbjct: 24 QYNLVGKIGEGTYGLVFLARTKTPPKRPIAIKKFKQSKDGDGVSPTAIREIMLLREISHE 83
Query: 68 NIVRLFDVI--HTENKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGV 125
N+V+L +V + L L F++ + DL + + + H L VK WQLL G+
Sbjct: 84 NVVKLVNVHINFADMSLYLAFDYAEYDLYEIIRHHRDKVGHS-LNTYTVKSLLWQLLNGL 142
Query: 126 AFCHENRILHRDLKPQNLLI----NNRGQLKLGDFGLARAFGIPVNTFSSE--VVTLWYR 179
+ H N I+HRDLKP N+L+ G +K+ DFGLAR + P+ S VVT+WYR
Sbjct: 143 NYLHSNWIIHRDLKPSNILVMGDAEEHGIVKIADFGLARIYQAPLKPLSDNGVVVTIWYR 202
Query: 180 APDVLMGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDE--------EQLKLIFDTMGT 231
AP++L+GS++Y +++D+W+ GCI AE++ KPLF G+ + +QL IF +G
Sbjct: 203 APELLLGSKHYTSAVDMWAVGCIFAELLTLKPLFQGAEAKSSQNPFQLDQLDKIFKILGH 262
Query: 232 PVEQTWPQVTQLAKYNPLLPPHMPRDLKQLLQNNTEEVLDDNVV---------DLLHGLL 282
P WP + L PH D++ + + + V NVV DLL +L
Sbjct: 263 PTMDKWPTLVNL--------PHWQNDVQHIQAHKYDSVGLHNVVHLNQKSPAYDLLSKML 314
Query: 283 QLNPDARLSAKDALNHPWF 301
+ +P R++A AL H +F
Sbjct: 315 EYDPLKRITASQALEHEYF 333
>At1g54610 [D] KOG0600 Cdc2-related protein kinase
Length = 572
Score = 184 bits (467), Expect = 1e-46
Identities = 111/303 (36%), Positives = 169/303 (55%), Gaps = 18/303 (5%)
Query: 11 FKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDS-EEGTPSTAIREISLMKELKHDNI 69
F++++K+G GTY+ VYK + TG VALK+V+ D+ E + REI +++ L H N+
Sbjct: 118 FEKIDKIGQGTYSNVYKAKDMLTGKIVALKKVRFDNLEPESVKFMAREILVLRRLDHPNV 177
Query: 70 VRLFDVIHTENK--LTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGVAF 127
V+L ++ + L LVF++MD+DL + S VK QL+ G+
Sbjct: 178 VKLEGLVTSRMSCSLYLVFQYMDHDLAGLASSPVVKFSESE-----VKCLMRQLISGLEH 232
Query: 128 CHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIP-VNTFSSEVVTLWYRAPDVLMG 186
CH +LHRD+K NLLI++ G LK+ DFGLA F +S VVTLWYRAP++L+G
Sbjct: 233 CHSRGVLHRDIKGSNLLIDDGGVLKIADFGLATIFDPNHKRPMTSRVVTLWYRAPELLLG 292
Query: 187 SRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWP--QVTQLA 244
+ +Y ID+WS GCILAE++ G+P+ PG + EQL I+ G+P E W + T A
Sbjct: 293 ATDYGVGIDLWSAGCILAELLAGRPIMPGRTEVEQLHKIYKLCGSPSEDYWKKGKFTHGA 352
Query: 245 KYNPLLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPWFAEY 304
Y P P R +++ ++ + + L+ LL + P+ R +A AL +F
Sbjct: 353 IYKPREP--YKRSIRETFKD-----FPPSSLPLIDALLSIEPEDRQTASAALKSEFFTSE 405
Query: 305 NHA 307
+A
Sbjct: 406 PYA 408
>At1g10210 [T] KOG0660 Mitogen-activated protein kinase
Length = 370
Score = 184 bits (466), Expect = 2e-46
Identities = 112/307 (36%), Positives = 169/307 (54%), Gaps = 19/307 (6%)
Query: 4 LLRYETRFKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPST-AIREISLMK 62
L +T++ ++ +G G Y V +N T VA+K++ E + +RE+ L++
Sbjct: 25 LFEIDTKYMPIKPIGRGAYGVVCSSVNSDTNEKVAIKKIHNVYENRIDALRTLRELKLLR 84
Query: 63 ELKHDNIVRLFDVIHTENKLT-----LVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYF 117
L+H+N++ L DV+ +K++ LV+E MD DL + + S + L D +YF
Sbjct: 85 HLRHENVIALKDVMMPIHKMSFKDVYLVYELMDTDLHQII------KSSQVLSNDHCQYF 138
Query: 118 QWQLLQGVAFCHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLW 177
+QLL+G+ + H ILHRDLKP NLL+N LK+ DFGLARA + VVT W
Sbjct: 139 LFQLLRGLKYIHSANILHRDLKPGNLLVNANCDLKICDFGLARASNTKGQFMTEYVVTRW 198
Query: 178 YRAPDVLMGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTW 237
YRAP++L+ NY TSID+WS GCI AE++ KP+F G+ QLKLI + +G+ E+
Sbjct: 199 YRAPELLLCCDNYGTSIDVWSVGCIFAELLGRKPIFQGTECLNQLKLIVNILGSQREEDL 258
Query: 238 PQV--TQLAKYNPLLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDA 295
+ + +Y LP L +L VL +DLL +L +P R+S +A
Sbjct: 259 EFIDNPKAKRYIRSLPYSPGMSLSRLYPG--AHVL---AIDLLQKMLVFDPSKRISVSEA 313
Query: 296 LNHPWFA 302
L HP+ A
Sbjct: 314 LQHPYMA 320
>SPAC31G5.09c [T] KOG0660 Mitogen-activated protein kinase
Length = 372
Score = 183 bits (464), Expect = 3e-46
Identities = 103/308 (33%), Positives = 168/308 (54%), Gaps = 22/308 (7%)
Query: 11 FKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPSTAIREISLMKELKHDNIV 70
++ + +G G Y V L+K +G+ VA+K++ + +REI L++ +H+NI+
Sbjct: 39 YEMINLIGQGAYGVVCAALHKPSGLKVAVKKIHPFNHPVFCLRTLREIKLLRHFRHENII 98
Query: 71 RLFDVIHTEN-----KLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGV 125
+ D++ + + +V E M+ DL + + ++ + H +YF +Q+L+ +
Sbjct: 99 SILDILPPPSYQELEDVYIVQELMETDLYRVIRSQPLSDDH-------CQYFTYQILRAL 151
Query: 126 AFCHENRILHRDLKPQNLLINNRGQLKLGDFGLAR---AFGIPVNTFSSEVVTLWYRAPD 182
H ++HRDLKP NLL+N LK+ DFGLAR A G + V T WYRAP+
Sbjct: 152 KAMHSAGVVHRDLKPSNLLLNANCDLKVADFGLARSTTAQGGNPGFMTEYVATRWYRAPE 211
Query: 183 VLMGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQV-- 240
+++ R Y +ID+WS GCILAEM+ +PLFPG + Q+ LI + +GTP + ++
Sbjct: 212 IMLSFREYSKAIDLWSTGCILAEMLSARPLFPGKDYHSQITLILNILGTPTMDDFSRIKS 271
Query: 241 TQLAKYNPLLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPW 300
+ KY LP K L + + +DLL LL NPD R++A++AL HP+
Sbjct: 272 ARARKYIKSLPFTPKVSFKALFPQASPD-----AIDLLEKLLTFNPDKRITAEEALKHPY 326
Query: 301 FAEYNHAN 308
A Y+ A+
Sbjct: 327 VAAYHDAS 334
>At4g22940 [D] KOG0600 Cdc2-related protein kinase
Length = 458
Score = 183 bits (464), Expect = 3e-46
Identities = 109/307 (35%), Positives = 170/307 (54%), Gaps = 31/307 (10%)
Query: 8 ETRFKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPSTAI-REISLMKELKH 66
E+ F++ E++G GT++ V+K + VALK ++ D I REI ++++L H
Sbjct: 100 ESHFEKQEQIGGGTFSKVFKARDLLRNKTVALKRIRFDINNSESIKCIAREIIILRKLDH 159
Query: 67 DNIVRLFDVI---HTENKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMD--LVKYFQWQL 121
N+++L ++ H + L L+FE+M++DL +S G+ VK + QL
Sbjct: 160 PNVIKLEGLMLVDHDSSTLYLIFEYMEHDLLGL-------SSLLGVHFSEPQVKCYMRQL 212
Query: 122 LQGVAFCHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNT--FSSEVVTLWYR 179
L+G+ CH N +LHRD+K NLLIN G LK+ DFGLA F P N+ ++ V TLWYR
Sbjct: 213 LRGLDHCHTNHVLHRDMKSSNLLINGDGVLKIADFGLATFFD-PHNSVPLTTHVATLWYR 271
Query: 180 APDVLMGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQ 239
P++L+G+ +Y +D+WS GC++ E+ GKP+ PG N+ +QL IF G+P + W +
Sbjct: 272 PPELLLGASHYGIGVDLWSTGCVIGELYAGKPILPGKNETDQLHKIFKLCGSPSDDYWTK 331
Query: 240 VTQLAKYNPLLP-----PHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKD 294
+ +L PL P H+ KQ +V+ LL LL ++PD R +A
Sbjct: 332 L-KLQLSTPLRPIYPYGSHIAETFKQ---------FPASVISLLETLLSIDPDFRGTAAS 381
Query: 295 ALNHPWF 301
AL +F
Sbjct: 382 ALKSKYF 388
>At1g74330 [D] KOG0600 Cdc2-related protein kinase
Length = 445
Score = 183 bits (464), Expect = 3e-46
Identities = 106/299 (35%), Positives = 171/299 (56%), Gaps = 20/299 (6%)
Query: 11 FKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDS-EEGTPSTAIREISLMKELKHDNI 69
F++LEK+G GTY+ V++ + TG VALK+V+ D+ E + REI +++ L H NI
Sbjct: 121 FEKLEKIGQGTYSNVFRAVETETGRIVALKKVRFDNFEPESVKFMAREILILRRLNHPNI 180
Query: 70 VRLFDVIHTENK--LTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGVAF 127
++L +I ++ + LVFE+M++DL + + + +K + QLL G+
Sbjct: 181 IKLEGLITSKLSCNIQLVFEYMEHDLTGLLSSPDIK-----FTTPQIKCYMKQLLSGLDH 235
Query: 128 CHENRILHRDLKPQNLLINNRGQLKLGDFGLAR---AFGIPVNTFSSEVVTLWYRAPDVL 184
CH ++HRD+K NLL++N G LK+ DFGLA + G +S VVTLWYR P++L
Sbjct: 236 CHSRGVMHRDIKGSNLLLSNEGILKVADFGLANFSNSSGHKKKPLTSRVVTLWYRPPELL 295
Query: 185 MGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQLA 244
+G+ +Y S+D+WS GC+ AE+++GKP+ G + EQL IF G+P E W +
Sbjct: 296 LGATDYGASVDLWSVGCVFAELLLGKPILRGRTEVEQLHKIFKLCGSPPEDYWKK--SKL 353
Query: 245 KYNPLLPPHMPRD--LKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPWF 301
+ L P D L++ L++ L + ++L+ LL ++P R +A AL +F
Sbjct: 354 PHAMLFKPQQTYDSCLRETLKD-----LSETEINLIETLLSIDPHKRGTASSALVSQYF 407
>At1g59580 [T] KOG0660 Mitogen-activated protein kinase
Length = 376
Score = 183 bits (464), Expect = 3e-46
Identities = 111/307 (36%), Positives = 169/307 (54%), Gaps = 19/307 (6%)
Query: 4 LLRYETRFKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPST-AIREISLMK 62
L +T++ ++ +G G Y V +N+ + VA+K++ E + +RE+ L++
Sbjct: 25 LFEIDTKYVPIKPIGRGAYGVVCSSVNRESNERVAIKKIHNVFENRIDALRTLRELKLLR 84
Query: 63 ELKHDNIVRLFDVIHTENKLT-----LVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYF 117
L+H+N+V L DV+ +K + LV+E MD DL + + S + L D +YF
Sbjct: 85 HLRHENVVALKDVMMANHKRSFKDVYLVYELMDTDLHQII------KSSQVLSNDHCQYF 138
Query: 118 QWQLLQGVAFCHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLW 177
+QLL+G+ + H ILHRDLKP NLL+N LK+ DFGLAR + VVT W
Sbjct: 139 LFQLLRGLKYIHSANILHRDLKPGNLLVNANCDLKICDFGLARTSNTKGQFMTEYVVTRW 198
Query: 178 YRAPDVLMGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTW 237
YRAP++L+ NY TSID+WS GCI AE++ KP+FPG+ Q+KLI + +G+ E+
Sbjct: 199 YRAPELLLCCDNYGTSIDVWSVGCIFAELLGRKPVFPGTECLNQIKLIINILGSQREEDL 258
Query: 238 PQV--TQLAKYNPLLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDA 295
+ + +Y LP +L VL +DLL +L L+P R+S +A
Sbjct: 259 EFIDNPKAKRYIESLPYSPGISFSRLYPG--ANVL---AIDLLQKMLVLDPSKRISVTEA 313
Query: 296 LNHPWFA 302
L HP+ A
Sbjct: 314 LQHPYMA 320
>At2g18170 [T] KOG0660 Mitogen-activated protein kinase
Length = 368
Score = 182 bits (462), Expect = 5e-46
Identities = 110/307 (35%), Positives = 166/307 (53%), Gaps = 19/307 (6%)
Query: 4 LLRYETRFKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPST-AIREISLMK 62
L +T++ ++ +G G Y V +N+ T VA+K++ E + +RE+ L++
Sbjct: 25 LFEIDTKYVPIKPIGRGAYGVVCSSINRETNERVAIKKIHNVFENRVDALRTLRELKLLR 84
Query: 63 ELKHDNIVRLFDVIHTENKLT-----LVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYF 117
++H+N++ L DV+ N+ + LV+E MD DL + + S + L D KYF
Sbjct: 85 HVRHENVIALKDVMLPANRSSFKDVYLVYELMDTDLHQII------KSSQSLSDDHCKYF 138
Query: 118 QWQLLQGVAFCHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLW 177
+QLL+G+ + H ILHRDLKP NLL+N LK+ DFGLAR + VVT W
Sbjct: 139 LFQLLRGLKYLHSANILHRDLKPGNLLVNANCDLKICDFGLARTSQGNEQFMTEYVVTRW 198
Query: 178 YRAPDVLMGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQ-- 235
YRAP++L+ NY TSID+WS GCI AE++ KP+FPG+ QLKLI + +G+ E
Sbjct: 199 YRAPELLLCCDNYGTSIDVWSVGCIFAEILGRKPIFPGTECLNQLKLIINVVGSQQESDI 258
Query: 236 TWPQVTQLAKYNPLLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDA 295
+ + ++ LP L L + +DLL +L +P R+S DA
Sbjct: 259 RFIDNPKARRFIKSLPYSRGTHLSNLYPQ-----ANPLAIDLLQRMLVFDPTKRISVTDA 313
Query: 296 LNHPWFA 302
L HP+ A
Sbjct: 314 LLHPYMA 320
>Hs20986501 [T] KOG0660 Mitogen-activated protein kinase
Length = 816
Score = 181 bits (460), Expect = 9e-46
Identities = 105/308 (34%), Positives = 168/308 (54%), Gaps = 24/308 (7%)
Query: 11 FKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPST-AIREISLMKELKHDNI 69
++ +E +GNG Y V + TG VA+K++ + T + +RE+ ++K KHDNI
Sbjct: 55 YEIIETIGNGAYGVVSSARRRLTGQQVAIKKIPNAFDVVTNAKRTLRELKILKHFKHDNI 114
Query: 70 VRLFDVIHTE------NKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQ 123
+ + D++ + +V + M++DL + + +S + L ++ V+YF +QLL+
Sbjct: 115 IAIKDILRPTVPYGEFKSVYVVLDLMESDLHQII------HSSQPLTLEHVRYFLYQLLR 168
Query: 124 GVAFCHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPV---NTFSSE-VVTLWYR 179
G+ + H +++HRDLKP NLL+N +LK+GDFG+AR F +E V T WYR
Sbjct: 169 GLKYMHSAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQYFMTEYVATRWYR 228
Query: 180 APDVLMGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQ 239
AP++++ Y +ID+WS GCI EM+ + LFPG N QL+LI +GTP
Sbjct: 229 APELMLSLHEYTQAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIMMVLGTPSPAVIQA 288
Query: 240 V--TQLAKYNPLLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALN 297
V ++ Y LPP P + + D + LL +L+ P AR+SA AL
Sbjct: 289 VGAERVRAYIQSLPPRQPVPWETVYPG-----ADRQALSLLGRMLRFEPSARISAAAALR 343
Query: 298 HPWFAEYN 305
HP+ A+Y+
Sbjct: 344 HPFLAKYH 351
>Hs20986497 [T] KOG0660 Mitogen-activated protein kinase
Length = 816
Score = 181 bits (460), Expect = 9e-46
Identities = 105/308 (34%), Positives = 168/308 (54%), Gaps = 24/308 (7%)
Query: 11 FKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPST-AIREISLMKELKHDNI 69
++ +E +GNG Y V + TG VA+K++ + T + +RE+ ++K KHDNI
Sbjct: 55 YEIIETIGNGAYGVVSSARRRLTGQQVAIKKIPNAFDVVTNAKRTLRELKILKHFKHDNI 114
Query: 70 VRLFDVIHTE------NKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQ 123
+ + D++ + +V + M++DL + + +S + L ++ V+YF +QLL+
Sbjct: 115 IAIKDILRPTVPYGEFKSVYVVLDLMESDLHQII------HSSQPLTLEHVRYFLYQLLR 168
Query: 124 GVAFCHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPV---NTFSSE-VVTLWYR 179
G+ + H +++HRDLKP NLL+N +LK+GDFG+AR F +E V T WYR
Sbjct: 169 GLKYMHSAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQYFMTEYVATRWYR 228
Query: 180 APDVLMGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQ 239
AP++++ Y +ID+WS GCI EM+ + LFPG N QL+LI +GTP
Sbjct: 229 APELMLSLHEYTQAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIMMVLGTPSPAVIQA 288
Query: 240 V--TQLAKYNPLLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALN 297
V ++ Y LPP P + + D + LL +L+ P AR+SA AL
Sbjct: 289 VGAERVRAYIQSLPPRQPVPWETVYPG-----ADRQALSLLGRMLRFEPSARISAAAALR 343
Query: 298 HPWFAEYN 305
HP+ A+Y+
Sbjct: 344 HPFLAKYH 351
>At1g18670 [D] KOG0600 Cdc2-related protein kinase
Length = 662
Score = 181 bits (459), Expect = 1e-45
Identities = 107/298 (35%), Positives = 169/298 (55%), Gaps = 17/298 (5%)
Query: 11 FKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDS-EEGTPSTAIREISLMKELKHDNI 69
F++LEK+G GTY++V++ TG VALK+V+ D+ E + REI ++++L H NI
Sbjct: 131 FEKLEKIGQGTYSSVFRARETETGRIVALKKVRFDNFEPESVRFMAREILILRKLNHPNI 190
Query: 70 VRLFDVIHTENKLT--LVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGVAF 127
++L ++ ++ + LVFE+M++DL + + + +K + QLL G+
Sbjct: 191 IKLEGIVTSKLSCSIHLVFEYMEHDLTGLLSSPDID-----FTTPQIKCYMKQLLSGLDH 245
Query: 128 CHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNT--FSSEVVTLWYRAPDVLM 185
CH ++HRD+K NLL+NN G LK+ DFGLA N +S VVTLWYR P++L+
Sbjct: 246 CHARGVMHRDIKGSNLLVNNEGILKVADFGLANFCNASGNKQPLTSRVVTLWYRPPELLL 305
Query: 186 GSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQLAK 245
G+ Y S+D+WS GC+ AE+++GKP+ G + EQL IF G+P E W +
Sbjct: 306 GATEYGASVDLWSVGCVFAELLIGKPVLQGRTEVEQLHKIFKLCGSPPEDYWKK--SKLP 363
Query: 246 YNPLLPPHMPRD--LKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPWF 301
+ L P D L++ L+ + L D ++L+ LL + P R +A AL +F
Sbjct: 364 HAMLFKPQQHYDGCLRETLK---LKGLSDADINLIETLLSIQPHKRGTASTALVSQYF 418
>7297009 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 392
Score = 181 bits (459), Expect = 1e-45
Identities = 105/304 (34%), Positives = 165/304 (53%), Gaps = 23/304 (7%)
Query: 10 RFKQLEKVGNGTYATVYKGLNKTTGVYVALKE-VKLDSEEGTPSTAIREISLMKELKHDN 68
R+++L ++G G+Y VYK ++ TG VA+K V+ + + A+REI L+K LKH N
Sbjct: 3 RYEKLSRLGEGSYGVVYKCRDRETGALVAVKRFVESEDDPAIRKIALREIRLLKNLKHPN 62
Query: 69 IVRLFDVIHTENKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGVAFC 128
+V L +V + +L LVFEF + + ++ +G L K +Q L GVA+C
Sbjct: 63 LVSLLEVFRRKRRLHLVFEFCELTVLHELERHPQGCPEH-----LTKQICYQTLLGVAYC 117
Query: 129 HENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGSR 188
H+ LHRD+KP+N+L+ +GQ+KL DFG AR P ++ V T WYRAP++L+G
Sbjct: 118 HKQGCLHRDIKPENILLTAQGQVKLCDFGFARMLS-PGENYTDYVATRWYRAPELLVGDT 176
Query: 189 NYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQLAKYN- 247
Y T +D+W+ GC+ AE++ G+ L+PG +D +QL LI T+G P+ Q+ N
Sbjct: 177 QYGTPVDVWAIGCLFAELVRGEALWPGRSDVDQLYLIRKTLG----DLLPRHIQIFGQNE 232
Query: 248 -------PLLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPW 300
P+ P P + K ++ + +D L L +P R S + H +
Sbjct: 233 YFKGITLPVPPTLEPLEDKMPAKSQQNPL----TIDFLKKCLDKDPTKRWSCEKLTKHSY 288
Query: 301 FAEY 304
F +Y
Sbjct: 289 FDDY 292
>At4g13020 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 443
Score = 181 bits (458), Expect = 2e-45
Identities = 106/300 (35%), Positives = 170/300 (56%), Gaps = 13/300 (4%)
Query: 10 RFKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPSTAIREISLMKELKHDNI 69
R+K LE++G+GT +VYK +N T VA+K++K +RE+ +++L H +I
Sbjct: 11 RYKILEELGDGTCGSVYKAVNLETYEVVAVKKMKRKFYYWEECVNLREVKALRKLNHPHI 70
Query: 70 VRLFDVIHTENKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGVAFCH 129
++L +++ N+L +FE MD++L M R + S ++ F Q+LQG+A H
Sbjct: 71 IKLKEIVREHNELFFIFECMDHNLYHIMKERERPFSEGE-----IRSFMSQMLQGLAHMH 125
Query: 130 ENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGSRN 189
+N HRDLKP+NLL+ N LK+ DFGLAR + ++ V T WYRAP+VL+ S
Sbjct: 126 KNGYFHRDLKPENLLVTNN-ILKIADFGLAREVA-SMPPYTEYVSTRWYRAPEVLLQSSL 183
Query: 190 YCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQLAKYNPL 249
Y ++D+W+ G ILAE+ PLFPG ++ +QL I +G P T+P+ +++ +
Sbjct: 184 YTPAVDMWAVGAILAELYALTPLFPGESEIDQLYKICCVLGKPDWTTFPEAKSISRIMSI 243
Query: 250 LPPHMPRD-LKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPWFAEYNHAN 308
P+ + LL N E +DL++ L +P R +A +ALNHP+F+ A+
Sbjct: 244 SHTEFPQTRIADLLPNAAPE-----AIDLINRLCSWDPLKRPTADEALNHPFFSMATQAS 298
>Hs20986529 [T] KOG0660 Mitogen-activated protein kinase
Length = 360
Score = 180 bits (456), Expect = 3e-45
Identities = 102/304 (33%), Positives = 157/304 (51%), Gaps = 20/304 (6%)
Query: 10 RFKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPSTAIREISLMKELKHDNI 69
R+ L +G G Y V + V VA+K++ + +REI ++ +H+NI
Sbjct: 24 RYTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKISPFEHQTYCQRTLREIKILLRFRHENI 83
Query: 70 VRLFDVIHTEN-----KLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQG 124
+ + D+I + +V + M+ DL K + ++ N H + YF +Q+L+G
Sbjct: 84 IGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQHLSNDH-------ICYFLYQILRG 136
Query: 125 VAFCHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIP---VNTFSSEVVTLWYRAP 181
+ + H +LHRDLKP NLL+N LK+ DFGLAR + V T WYRAP
Sbjct: 137 LKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTGFLTEYVATRWYRAP 196
Query: 182 DVLMGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVT 241
++++ S+ Y SIDIWS GCILAEM+ +P+FPG + +QLK I +G+P ++ +
Sbjct: 197 EIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLKHILGILGSPSQEDLNCII 256
Query: 242 QLAKYNPLLP-PHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPW 300
L N LL PH ++ N D +DLL +L NP R+ + AL HP+
Sbjct: 257 NLKARNYLLSLPHK----NKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPY 312
Query: 301 FAEY 304
+Y
Sbjct: 313 LEQY 316
>Hs20551615 [K] KOG0666 Cyclin C-dependent kinase CDK8
Length = 358
Score = 179 bits (453), Expect = 6e-45
Identities = 109/320 (34%), Positives = 172/320 (53%), Gaps = 40/320 (12%)
Query: 16 KVGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGT--PSTAIREISLMKELKHDNIVRLF 73
KVG GTY VYK K KE L EGT +A REI+L++ELKH N++ L
Sbjct: 26 KVGRGTYGHVYKARRKDGKDE---KEYALKQIEGTGISMSACREIALLRELKHPNVIALQ 82
Query: 74 DVI--HTENKLTLVFEFMDNDLKKFMDNRNKGNSHKG---LEMDLVKYFQWQLLQGVAFC 128
V H++ K+ L+F++ ++DL + ++K L +VK +Q+L G+ +
Sbjct: 83 KVFLSHSDRKVWLLFDYAEHDLWHIIKFHRASKANKKPMQLPRSMVKSLLYQILDGIHYL 142
Query: 129 HENRILHRDLKPQNLLINN----RGQLKLGDFGLARAFGIPVNTFSS---EVVTLWYRAP 181
H N +LHRDLKP N+L+ RG++K+ D G AR F P+ + VVT WYRAP
Sbjct: 143 HANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWYRAP 202
Query: 182 DVLMGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDE---------EQLKLIFDTMGTP 232
++L+G+R+Y +IDIW+ GCI AE++ +P+F ++ +QL IF MG P
Sbjct: 203 ELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPFHHDQLDRIFSVMGFP 262
Query: 233 VEQTWPQVTQLAKYNPLLPPHMPRDLKQLLQNNTEEVL---------DDNVVDLLHGLLQ 283
++ W + ++ +Y P + +D ++ N+ + D V LL LL
Sbjct: 263 ADKDWEDIRKMPEY-----PTLQKDFRRTTYANSSLIKYMEKHKVKPDSKVFLLLQKLLT 317
Query: 284 LNPDARLSAKDALNHPWFAE 303
++P R++++ AL P+F E
Sbjct: 318 MDPTKRITSEQALQDPYFQE 337
>7291043 [T] KOG0660 Mitogen-activated protein kinase
Length = 392
Score = 178 bits (452), Expect = 8e-45
Identities = 116/321 (36%), Positives = 172/321 (53%), Gaps = 36/321 (11%)
Query: 8 ETRFKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDS--EEGTPSTAIREISLMKELK 65
E+ F +++G G Y V+K ++ T VALK+V D+ +E RE+ ++ +
Sbjct: 22 ESIFDVRKRMGKGAYGIVWKATDRRTKNTVALKKV-FDAFRDETDAQRTYREVIFLRAFR 80
Query: 66 -HDNIVRLFDVIHTENKLT--LVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLL 122
H NIVRL D+ N L LVFEFM++DL + +GN K + V Y QL+
Sbjct: 81 CHPNIVRLVDIFKASNNLDFYLVFEFMESDLHNVI---KRGNVLKDVHKRFVMY---QLI 134
Query: 123 QGVAFCHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGI--------PVNTFSSEVV 174
+ F H ++HRDLKP N+LI+++ +LK+ DFGLAR + V
Sbjct: 135 NAIKFIHSGNVIHRDLKPSNILIDSKCRLKVADFGLARTLSSRRIYDDLEQDGMLTDYVA 194
Query: 175 TLWYRAPDVLMGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVE 234
T WYRAP++L+ SRNY ID+W GCIL EMI KPLF G++ Q++ I ++
Sbjct: 195 TRWYRAPEILVASRNYTKGIDMWGLGCILGEMIRQKPLFQGTSTVNQIEKIVTSL----- 249
Query: 235 QTWPQVTQL--AKYNP-----LLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPD 287
P VT+L A P LL ++ RD + L + DD + L+ LL LNP
Sbjct: 250 ---PNVTKLDIASIGPSFGSVLLSRNIQRDRRYSLDEMMKNCCDDG-ISLVKALLVLNPH 305
Query: 288 ARLSAKDALNHPWFAEYNHAN 308
RL+AK+A+ HP+ + + +A+
Sbjct: 306 NRLTAKEAIRHPYVSRFQYAS 326
>Hs20986531 [T] KOG0660 Mitogen-activated protein kinase
Length = 360
Score = 178 bits (451), Expect = 1e-44
Identities = 101/304 (33%), Positives = 156/304 (51%), Gaps = 20/304 (6%)
Query: 10 RFKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPSTAIREISLMKELKHDNI 69
R+ L +G G Y V + V VA+K++ + +REI ++ +H+NI
Sbjct: 24 RYTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKISPFEHQTYCQRTLREIKILLRFRHENI 83
Query: 70 VRLFDVIHTEN-----KLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQG 124
+ + D+I + +V + M+ DL K + ++ N H + YF +Q+L+G
Sbjct: 84 IGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQHLSNDH-------ICYFLYQILRG 136
Query: 125 VAFCHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIP---VNTFSSEVVTLWYRAP 181
+ + H +LHRDLKP NLL+N LK+ DFGLAR + V T WYRAP
Sbjct: 137 LKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTGFLTEYVATRWYRAP 196
Query: 182 DVLMGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVT 241
++++ S+ Y SIDIWS GCILAEM+ +P+FPG + +QL I +G+P ++ +
Sbjct: 197 EIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCII 256
Query: 242 QLAKYNPLLP-PHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPW 300
L N LL PH ++ N D +DLL +L NP R+ + AL HP+
Sbjct: 257 NLKARNYLLSLPHK----NKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPY 312
Query: 301 FAEY 304
+Y
Sbjct: 313 LEQY 316
>At4g36450 [T] KOG0660 Mitogen-activated protein kinase
Length = 361
Score = 178 bits (451), Expect = 1e-44
Identities = 109/308 (35%), Positives = 169/308 (54%), Gaps = 28/308 (9%)
Query: 4 LLRYETRFKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPST-AIREISLMK 62
L +T++ ++ +G G Y V +N T VA+K++ E + +RE+ L++
Sbjct: 25 LFEIDTKYVPIKPIGRGAYGVVCSSINSETNERVAIKKIHNVFENRIDALRTLRELKLLR 84
Query: 63 ELKHDNIVRLFDVIHTENKLT-----LVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYF 117
++H+N++ L DV+ ++ + LV+E MD+DL + + S + L D KYF
Sbjct: 85 HVRHENVISLKDVMLPTHRYSFRDVYLVYELMDSDLNQII------KSSQSLSDDHCKYF 138
Query: 118 QWQLLQGVAFCHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSE-VVTL 176
+QLL+G+ + H ILHRDLKP NLL+N LK+ DFGLAR + F +E VVT
Sbjct: 139 LFQLLRGLKYLHSANILHRDLKPGNLLVNANCDLKICDFGLARTY----EQFMTEYVVTR 194
Query: 177 WYRAPDVLMGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQT 236
WYRAP++L+ NY TSID+WS GCI AE++ KP+FPG+ QLKLI + +G+ +Q
Sbjct: 195 WYRAPELLLCCDNYGTSIDVWSVGCIFAEILGRKPIFPGTECLNQLKLIINVVGS--QQD 252
Query: 237 WP----QVTQLAKYNPLLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSA 292
W + ++ LP + + + +DLL +L +P R+S
Sbjct: 253 WDLQFIDNQKARRFIKSLPFSKGTHFSHIYPH-----ANPLAIDLLQRMLVFDPTKRISV 307
Query: 293 KDALNHPW 300
DAL HP+
Sbjct: 308 SDALLHPY 315
>At2g43790 [T] KOG0660 Mitogen-activated protein kinase
Length = 395
Score = 178 bits (451), Expect = 1e-44
Identities = 108/299 (36%), Positives = 171/299 (57%), Gaps = 35/299 (11%)
Query: 17 VGNGTYATVYKGLNKTTGVYVALKEV------KLDSEEGTPSTAIREISLMKELKHDNIV 70
+G G Y V +N T VA+K++ K+D++ +REI L++ + H+NIV
Sbjct: 69 IGKGAYGIVCSAMNSETNESVAIKKIANAFDNKIDAKR-----TLREIKLLRHMDHENIV 123
Query: 71 RLFDVI-----HTENKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGV 125
+ D+I + N + + +E MD DL + + S++ L + +YF +Q+L+G+
Sbjct: 124 AIRDIIPPPLRNAFNDVYIAYELMDTDLHQII------RSNQALSEEHCQYFLYQILRGL 177
Query: 126 AFCHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSE-VVTLWYRAPDVL 184
+ H +LHRDLKP NLL+N LK+ DFGLAR + F +E VVT WYRAP++L
Sbjct: 178 KYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARVTS--ESDFMTEYVVTRWYRAPELL 235
Query: 185 MGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQLA 244
+ S +Y +ID+WS GCI E++ KPLFPG + QL+L+ + +GTP E+ + + A
Sbjct: 236 LNSSDYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIGTPSEEELEFLNENA 295
Query: 245 K-YNPLLPPHMPRDLKQLLQNNTEE--VLDDNVVDLLHGLLQLNPDARLSAKDALNHPW 300
K Y LPP+ PR Q+ T++ + +DL+ +L +P R++ DAL HP+
Sbjct: 296 KRYIRQLPPY-PR------QSITDKFPTVHPLAIDLIEKMLTFDPRRRITVLDALAHPY 347
>At1g57700 [D] KOG0600 Cdc2-related protein kinase
Length = 686
Score = 178 bits (451), Expect = 1e-44
Identities = 106/295 (35%), Positives = 169/295 (56%), Gaps = 20/295 (6%)
Query: 11 FKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKL-DSEEGTPSTAIREISLMKELKHDNI 69
F++LE +G GTY++VY+ + T VALK+V+ + + + REI +++ L H N+
Sbjct: 146 FEKLEMIGQGTYSSVYRARDLETNQIVALKKVRFANMDPESVRFMAREIIILRRLNHPNV 205
Query: 70 VRLFDVIHTE--NKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGVAF 127
++L +I ++ + L+FE+MD+DL S G++ + QLL G+
Sbjct: 206 MKLEGLIISKASGSMYLIFEYMDHDLAGLA-------STPGIKFSQAQ----QLLLGLEH 254
Query: 128 CHENRILHRDLKPQNLLINNRGQLKLGDFGLARAF-GIPVNTFSSEVVTLWYRAPDVLMG 186
CH +LHRD+K NLL++ LK+GDFGL+ + G +S VVTLWYR P++L+G
Sbjct: 255 CHSCGVLHRDIKCSNLLLDRNNNLKIGDFGLSNFYRGQRKQPLTSRVVTLWYRPPELLLG 314
Query: 187 SRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQLAKY 246
S +Y ++D+WS GCILAE+ GKPL PG + EQ+ IF G+P E+ W + ++
Sbjct: 315 STDYGVTVDLWSTGCILAELFTGKPLLPGRTEVEQMHKIFKLCGSPSEEYWRR--SRLRH 372
Query: 247 NPLLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPWF 301
+ P P K+ + + ++ L + + LL LL + PDAR +A AL +F
Sbjct: 373 ATIFKPQHP--YKRCVADTFKD-LPSSALALLEVLLAVEPDARGTASSALQSEFF 424
>7300773 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 302
Score = 178 bits (451), Expect = 1e-44
Identities = 104/291 (35%), Positives = 166/291 (56%), Gaps = 15/291 (5%)
Query: 9 TRFKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPS-TAIREISLMKELKHD 67
+R+K LEK+G G + V+K ++ VA+K+V L ++ G + +REI ++ K +
Sbjct: 7 SRYKMLEKIGEGVHGCVFKAIDLQRNKEVAIKKVALKNKFGNIALNTLREIKTLQLCKSE 66
Query: 68 NIVRLFDVIHTENKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGVAF 127
I+ + D+ L+LV E+ + L NR K + L V+ F Q+ +G+A+
Sbjct: 67 YILDIIDIYPDLTGLSLVLEYQPDTLY----NRLKSEVNP-LSRQQVRKFAHQMFKGIAY 121
Query: 128 CHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNT---FSSEVVTLWYRAPDVL 184
HE ++HRD+KP NLLI++ LK+ DFGLAR + P + +S +V T WYRAP++L
Sbjct: 122 LHEAGLMHRDIKPANLLISDTDMLKIADFGLARLY-FPEDESRLYSPQVSTRWYRAPEIL 180
Query: 185 MGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQLA 244
GS+ Y T +D+W+ GC++AEM+ G PLF G+ D EQL +I T+G+P WP++T L
Sbjct: 181 FGSQKYGTGVDMWAAGCVVAEMLRGVPLFAGTTDIEQLAIIIRTLGSPRLNQWPELTSLP 240
Query: 245 KYNPL-LPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKD 294
Y+ + P + L + T V ++L+ L+ NP RL A +
Sbjct: 241 DYSKIRFPNSVGIHWDNLFPSCTHAV----EINLVSNLVVYNPKNRLKASE 287
>CE24971 [T] KOG0660 Mitogen-activated protein kinase
Length = 444
Score = 177 bits (450), Expect = 1e-44
Identities = 104/310 (33%), Positives = 157/310 (50%), Gaps = 20/310 (6%)
Query: 4 LLRYETRFKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPSTAIREISLMKE 63
L R+ L +G G Y V L+ T VA+K++ + +REI ++
Sbjct: 89 LFEVAPRYVNLSYIGEGAYGMVASALDTITRDRVAIKKISPFEHQTFCQRTLREIKILNR 148
Query: 64 LKHDNIVRLFDVIHTEN-----KLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQ 118
KH+NI+ + ++I +E + +V M+ DL K + + N H V YF
Sbjct: 149 FKHENIINIQEIIRSETVDSLKDIYIVQCLMETDLYKLLKTQKLSNDH-------VCYFL 201
Query: 119 WQLLQGVAFCHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNT---FSSEVVT 175
+Q+L+G+ + H +LHRDLKP NLL+N LK+ DFGLAR + + V T
Sbjct: 202 YQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVTDPQTDHTGFLTEYVAT 261
Query: 176 LWYRAPDVLMGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQ 235
WYRAP++++ S+ Y SID+WS GCILAEM+ +PLFPG + +QL LI +G+P
Sbjct: 262 RWYRAPEIMLNSKGYTKSIDVWSVGCILAEMLSNRPLFPGKHYLDQLNLILAVVGSPSNA 321
Query: 236 TWP-QVTQLAKYNPLLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKD 294
+ A+ + PH P+ L D +DLL +L NP R+ +
Sbjct: 322 DLQCIINDKARSYLISLPHKPKQPWARLYPGA----DPRALDLLDKMLTFNPHNRIDIEQ 377
Query: 295 ALNHPWFAEY 304
AL HP+ +Y
Sbjct: 378 ALAHPYLEQY 387
>CE18608 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 342
Score = 177 bits (450), Expect = 1e-44
Identities = 106/300 (35%), Positives = 173/300 (57%), Gaps = 24/300 (8%)
Query: 11 FKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSE-EGTPSTAIREISLMKELK---H 66
F+ + +G G Y VY+ + G ALK++ + S+ EG P + +REI++MK L H
Sbjct: 38 FQIHQALGKGAYGNVYRVRSLHDGKDYALKQIMISSKNEGIPQSVLREITVMKHLARKAH 97
Query: 67 DNIVRLFDVIHTEN------KLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQ 120
NI+ L V H + K+ ++ E D DL F+ N +G+ K+ Q
Sbjct: 98 PNIISLKSVFHQLDPVRAILKINMIMERCDWDLHTFLRN-----IPRGVPEQQAKHVTAQ 152
Query: 121 LLQGVAFCHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRA 180
+++ + F H + I+HRDLKPQN+L+N +KL DFGL++ + F++ VVTLWYR+
Sbjct: 153 IVRALDFLHTHSIIHRDLKPQNILLNRDQTVKLADFGLSKEYS-NTTAFTTLVVTLWYRS 211
Query: 181 PDVLMGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQV 240
P+VL+ S Y +++D+W+ GCI++E+ +PLF G N+ EQL IF MGTPV + WP
Sbjct: 212 PEVLLQSY-YNSTVDMWALGCIVSEIYCRQPLFVGQNEAEQLTDIFKKMGTPVGKDWPSE 270
Query: 241 TQLAKYNPLLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPW 300
+ +A+ + P + P +LK L +++ ++ + L+ + RLSA+ AL+HP+
Sbjct: 271 SVIARDS--FPQYRPTNLKDLSPQMSKQ-----AIEFVQQCLRYDHSKRLSARGALSHPF 323
>CE01583 [T] KOG0660 Mitogen-activated protein kinase
Length = 376
Score = 177 bits (450), Expect = 1e-44
Identities = 104/310 (33%), Positives = 157/310 (50%), Gaps = 20/310 (6%)
Query: 4 LLRYETRFKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPSTAIREISLMKE 63
L R+ L +G G Y V L+ T VA+K++ + +REI ++
Sbjct: 21 LFEVAPRYVNLSYIGEGAYGMVASALDTITRDRVAIKKISPFEHQTFCQRTLREIKILNR 80
Query: 64 LKHDNIVRLFDVIHTEN-----KLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQ 118
KH+NI+ + ++I +E + +V M+ DL K + + N H V YF
Sbjct: 81 FKHENIINIQEIIRSETVDSLKDIYIVQCLMETDLYKLLKTQKLSNDH-------VCYFL 133
Query: 119 WQLLQGVAFCHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNT---FSSEVVT 175
+Q+L+G+ + H +LHRDLKP NLL+N LK+ DFGLAR + + V T
Sbjct: 134 YQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVTDPQTDHTGFLTEYVAT 193
Query: 176 LWYRAPDVLMGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQ 235
WYRAP++++ S+ Y SID+WS GCILAEM+ +PLFPG + +QL LI +G+P
Sbjct: 194 RWYRAPEIMLNSKGYTKSIDVWSVGCILAEMLSNRPLFPGKHYLDQLNLILAVVGSPSNA 253
Query: 236 TWP-QVTQLAKYNPLLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKD 294
+ A+ + PH P+ L D +DLL +L NP R+ +
Sbjct: 254 DLQCIINDKARSYLISLPHKPKQPWARLYPGA----DPRALDLLDKMLTFNPHNRIDIEQ 309
Query: 295 ALNHPWFAEY 304
AL HP+ +Y
Sbjct: 310 ALAHPYLEQY 319
>CE28918 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 406
Score = 177 bits (449), Expect = 2e-44
Identities = 105/296 (35%), Positives = 171/296 (57%), Gaps = 24/296 (8%)
Query: 15 EKVGNGTYATVYKGLNKTTGVYVALKEVKLDSE-EGTPSTAIREISLMKELK---HDNIV 70
+ +G G Y VY+ + G ALK++ + S+ EG P + +REI++MK L H NI+
Sbjct: 106 QALGKGAYGNVYRVRSLHDGKDYALKQIMISSKNEGIPQSVLREITVMKHLARKAHPNII 165
Query: 71 RLFDVIHTEN------KLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQG 124
L V H + K+ ++ E D DL F+ N +G+ K+ Q+++
Sbjct: 166 SLKSVFHQLDPVRAILKINMIMERCDWDLHTFLRN-----IPRGVPEQQAKHVTAQIVRA 220
Query: 125 VAFCHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVL 184
+ F H + I+HRDLKPQN+L+N +KL DFGL++ + F++ VVTLWYR+P+VL
Sbjct: 221 LDFLHTHSIIHRDLKPQNILLNRDQTVKLADFGLSKEYS-NTTAFTTLVVTLWYRSPEVL 279
Query: 185 MGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQLA 244
+ S Y +++D+W+ GCI++E+ +PLF G N+ EQL IF MGTPV + WP + +A
Sbjct: 280 LQSY-YNSTVDMWALGCIVSEIYCRQPLFVGQNEAEQLTDIFKKMGTPVGKDWPSESVIA 338
Query: 245 KYNPLLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPW 300
+ + P + P +LK L +++ ++ + L+ + RLSA+ AL+HP+
Sbjct: 339 RDS--FPQYRPTNLKDLSPQMSKQ-----AIEFVQQCLRYDHSKRLSARGALSHPF 387
>YBL016w [T] KOG0660 Mitogen-activated protein kinase
Length = 353
Score = 177 bits (448), Expect = 2e-44
Identities = 101/316 (31%), Positives = 166/316 (51%), Gaps = 30/316 (9%)
Query: 11 FKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPSTAIREISLMKELKHDNIV 70
F+ +G G Y V +K TG VA+K+++ + +REI ++K KH+NI+
Sbjct: 13 FQLKSLLGEGAYGVVCSATHKPTGEIVAIKKIEPFDKPLFALRTLREIKILKHFKHENII 72
Query: 71 RLFDVIHTE-----NKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGV 125
+F++ + N++ ++ E M DL + + + + H ++YF +Q L+ V
Sbjct: 73 TIFNIQRPDSFENFNEVYIIQELMQTDLHRVISTQMLSDDH-------IQYFIYQTLRAV 125
Query: 126 AFCHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPV----------NTFSSEVVT 175
H + ++HRDLKP NLLIN+ LK+ DFGLAR + + V T
Sbjct: 126 KVLHGSNVIHRDLKPSNLLINSNCDLKVCDFGLARIIDESAADNSEPTGQQSGMTEYVAT 185
Query: 176 LWYRAPDVLMGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQ 235
WYRAP+V++ S Y ++D+WSCGCILAE+ + +P+FPG + QL LIF +GTP
Sbjct: 186 RWYRAPEVMLTSAKYSRAMDVWSCGCILAELFLRRPIFPGRDYRHQLLLIFGIIGTPHSD 245
Query: 236 T---WPQVTQLAKYNPLLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSA 292
+ + +Y LP + L+++ ++ +DLL +L +P R++A
Sbjct: 246 NDLRCIESPRAREYIKSLPMYPAAPLEKMFPR-----VNPKGIDLLQRMLVFDPAKRITA 300
Query: 293 KDALNHPWFAEYNHAN 308
K+AL HP+ Y+ N
Sbjct: 301 KEALEHPYLQTYHDPN 316
>CE20258 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 353
Score = 177 bits (448), Expect = 2e-44
Identities = 102/303 (33%), Positives = 165/303 (53%), Gaps = 24/303 (7%)
Query: 10 RFKQLEKVGNGTYATVYKGLNKTTGVYVALKE-VKLDSEEGTPSTAIREISLMKELKHDN 68
++ +L K+G G+Y VYK N+ TG VA+K+ V+ + + A+REI ++K+LKH N
Sbjct: 3 KYDRLSKLGEGSYGVVYKCKNRDTGQIVAIKKFVETEDDPHIKKIALREIRMLKQLKHQN 62
Query: 69 IVRLFDVIHTENKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGVAFC 128
+V L +V KL LVFE D + ++ N H G+ +L+K +QLL+ + FC
Sbjct: 63 LVGLIEVFKRNRKLHLVFELCDRTVLHELEK----NPH-GVNDELIKKIIYQLLEALKFC 117
Query: 129 HENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGSR 188
H ++ +HRD+KP+N+ + Q+KLGDFG AR ++ V T WYR+P++L+G
Sbjct: 118 HSHKCIHRDVKPENIFLTRNDQVKLGDFGFARIINT-TEMYTDYVATRWYRSPELLVGDV 176
Query: 189 NYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQLAKYNP 248
Y +DIW+ GC+ AE++ G+ L+PG +D +QL I T+G + P+ + + N
Sbjct: 177 QYGPPVDIWAVGCVYAELLTGEALWPGRSDIDQLYHIRKTLG----EFLPRHISIFRTNQ 232
Query: 249 LL-------PPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPWF 301
P H+ L L N + L D L +++PD R S + + H F
Sbjct: 233 FFFGLSIPEPEHL-EPLPSKLPNASSAQL-----DFLQKCFEMSPDRRFSCSELMLHGIF 286
Query: 302 AEY 304
+ +
Sbjct: 287 SNW 289
>7301110 [T] KOG0660 Mitogen-activated protein kinase
Length = 366
Score = 177 bits (448), Expect = 2e-44
Identities = 96/306 (31%), Positives = 170/306 (55%), Gaps = 27/306 (8%)
Query: 11 FKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPST-AIREISLMKELKHDNI 69
++ L+ VG+G Y V K + + T ++VA+K++ + + RE+ L+K + H+N+
Sbjct: 25 YQDLQPVGSGAYGQVSKAVVRGTNMHVAIKKLARPFQSAVHAKRTYRELRLLKHMDHENV 84
Query: 70 VRLFDVIHTE---------NKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQ 120
+ L D+ H ++ LV MD DL + ++ + H V++ +Q
Sbjct: 85 IGLLDIFHPHPANGSLENFQQVYLVTHLMDADLNNIIRMQHLSDDH-------VQFLVYQ 137
Query: 121 LLQGVAFCHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRA 180
+L+G+ + H ++HRDLKP N+ +N +L++ DFGLAR N + V T WYRA
Sbjct: 138 ILRGLKYIHSAGVIHRDLKPSNIAVNEDCELRILDFGLARP---TENEMTGYVATRWYRA 194
Query: 181 PDVLMGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQV 240
P++++ +Y ++DIWS GCI+AE+I + LFPG++ QL LI + +GTP + ++
Sbjct: 195 PEIMLNWMHYDQTVDIWSVGCIMAELITRRTLFPGTDHIHQLNLIMEMLGTPPAEFLKKI 254
Query: 241 T--QLAKYNPLLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNH 298
+ Y LPP R K + +N + +DLL +L+L+ + R++A++AL+H
Sbjct: 255 SSESARSYIQSLPPMKGRSFKNVFKN-----ANPLAIDLLEKMLELDAEKRITAEEALSH 309
Query: 299 PWFAEY 304
P+ +Y
Sbjct: 310 PYLEKY 315
>At4g01370 [T] KOG0660 Mitogen-activated protein kinase
Length = 376
Score = 176 bits (447), Expect = 3e-44
Identities = 107/304 (35%), Positives = 164/304 (53%), Gaps = 22/304 (7%)
Query: 14 LEKVGNGTYATVYKGLNKTTGVYVALKEV--KLDSEEGTPSTAIREISLMKELKHDNIVR 71
L +G G Y V N TG VA+K++ D+ T +REI L+K + H+N++
Sbjct: 46 LRPIGRGAYGIVCAATNSETGEEVAIKKIGNAFDNIIDAKRT-LREIKLLKHMDHENVIA 104
Query: 72 LFDVIHTE-----NKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGVA 126
+ D+I N + +V+E MD DL + + S++ L D ++F +QLL+G+
Sbjct: 105 VKDIIKPPQRENFNDVYIVYELMDTDLHQII------RSNQPLTDDHCRFFLYQLLRGLK 158
Query: 127 FCHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMG 186
+ H +LHRDLKP NLL+N LKLGDFGLAR + + VVT WYRAP++L+
Sbjct: 159 YVHSANVLHRDLKPSNLLLNANCDLKLGDFGLARTKS-ETDFMTEYVVTRWYRAPELLLN 217
Query: 187 SRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQT--WPQVTQLA 244
Y +IDIWS GCIL E + +PLFPG + QL+LI + +G+P + + + +
Sbjct: 218 CSEYTAAIDIWSVGCILGETMTREPLFPGKDYVHQLRLITELIGSPDDSSLGFLRSDNAR 277
Query: 245 KYNPLLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPWFAEY 304
+Y LP + ++ N + VDLL +L +P R++ +AL HP+ A
Sbjct: 278 RYVRQLPQYPRQNFAARFPN-----MSAGAVDLLEKMLVFDPSRRITVDEALCHPYLAPL 332
Query: 305 NHAN 308
+ N
Sbjct: 333 HDIN 336
>SPAC24B11.06c [T] KOG0660 Mitogen-activated protein kinase
Length = 349
Score = 176 bits (445), Expect = 5e-44
Identities = 105/301 (34%), Positives = 161/301 (52%), Gaps = 19/301 (6%)
Query: 9 TRFKQLEKVGNGTYATVYKGLNKTTGVYVALKEV-KLDSEEGTPSTAIREISLMKELKHD 67
TR+ L+ +G G + V ++ TG+ VA+K++ K S RE+ L+K L+H+
Sbjct: 18 TRYSDLQPIGMGAFGLVCSAKDQLTGMNVAVKKIMKPFSTPVLAKRTYRELKLLKHLRHE 77
Query: 68 NIVRLFDV-IHTENKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGVA 126
NI+ L D+ I + V E + DL + + +R LE ++YF +Q+L+G+
Sbjct: 78 NIISLSDIFISPFEDIYFVTELLGTDLHRLLTSRP-------LETQFIQYFLYQILRGLK 130
Query: 127 FCHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMG 186
F H ++HRDLKP N+LIN LK+ DFGLAR I + V T +YRAP++++
Sbjct: 131 FVHSAGVIHRDLKPSNILINENCDLKICDFGLAR---IQDPQMTGYVSTRYYRAPEIMLT 187
Query: 187 SRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQV--TQLA 244
+ Y +DIWS GCI AEMI GKPLFPG + Q +I + +GTP + +
Sbjct: 188 WQKYNVEVDIWSAGCIFAEMIEGKPLFPGRDHVNQFSIITELLGTPPMEVIETICSKNTL 247
Query: 245 KYNPLLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPWFAEY 304
++ LP + +N D + +DLL +L +P R+SA DAL H + A Y
Sbjct: 248 RFVQSLPQKEKVPFAEKFKN-----ADPDAIDLLEKMLVFDPRKRISAADALAHNYLAPY 302
Query: 305 N 305
+
Sbjct: 303 H 303
>Hs20562757 [T] KOG0660 Mitogen-activated protein kinase
Length = 379
Score = 176 bits (445), Expect = 5e-44
Identities = 98/305 (32%), Positives = 159/305 (52%), Gaps = 22/305 (7%)
Query: 10 RFKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPSTAIREISLMKELKHDNI 69
R+ QL+ +G G Y V + VA+K++ + +REI ++ +H+N+
Sbjct: 41 RYTQLQYIGEGAYGMVSSAYDHVRKTRVAIKKISPFEHQTYCQRTLREIQILLRFRHENV 100
Query: 70 VRLFDVIHTEN-----KLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQG 124
+ + D++ + +V + M+ DL K + ++ N H + YF +Q+L+G
Sbjct: 101 IGIRDILRASTLEAMRDVYIVQDLMETDLYKLLKSQQLSNDH-------ICYFLYQILRG 153
Query: 125 VAFCHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIP---VNTFSSEVVTLWYRAP 181
+ + H +LHRDLKP NLLIN LK+ DFGLAR + V T WYRAP
Sbjct: 154 LKYIHSANVLHRDLKPSNLLINTTCDLKICDFGLARIADPEHDHTGFLTEYVATRWYRAP 213
Query: 182 DVLMGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVT 241
++++ S+ Y SIDIWS GCILAEM+ +P+FPG + +QL I +G+P ++ +
Sbjct: 214 EIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCII 273
Query: 242 QLAKYNPL--LPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHP 299
+ N L LP +L + D +DLL +L NP+ R++ ++AL HP
Sbjct: 274 NMKARNYLQSLPSKTKVAWAKLFPKS-----DSKALDLLDRMLTFNPNKRITVEEALAHP 328
Query: 300 WFAEY 304
+ +Y
Sbjct: 329 YLEQY 333
>CE29478 [T] KOG0664 Nemo-like MAPK-related serine/threonine protein kinase
Length = 437
Score = 176 bits (445), Expect = 5e-44
Identities = 104/294 (35%), Positives = 164/294 (55%), Gaps = 13/294 (4%)
Query: 17 VGNGTYATVYKGLNKTTGVYVALKEV-KLDSEEGTPSTAIREISLMKELKHDNIVRLFDV 75
+G G + V+ + +G VALK++ + + REI ++ +HDN++ L D+
Sbjct: 49 IGYGAFGVVWSVTDPRSGKRVALKKMPNVFQNLASCKRVFREIKMLSSFRHDNVLSLLDI 108
Query: 76 IHTEN-----KLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGVAFCHE 130
+ N +L ++ E M +DL K + S + L D VK F +Q+L+G+ + H
Sbjct: 109 LQPANPSFFQELYVLTELMQSDLHKIIV------SPQALTPDHVKVFVYQILRGLKYLHT 162
Query: 131 NRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVN-TFSSEVVTLWYRAPDVLMGSRN 189
ILHRD+KP NLL+N+ LK+ DFGLAR + + EVVT +YRAP++LMG+R
Sbjct: 163 ANILHRDIKPGNLLVNSNCILKICDFGLARTWDQRDRLNMTHEVVTQYYRAPELLMGARR 222
Query: 190 YCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQLAKYNPL 249
Y ++DIWS GCI AE++ K LF + EQL++I D +GTP ++ + AK + L
Sbjct: 223 YTGAVDIWSVGCIFAELLQRKILFQAAGPIEQLQMIIDLLGTPSQEAMKYACEGAKNHVL 282
Query: 250 LPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPWFAE 303
D ++L + + + + VDLL LL +PD R+S ++AL H + E
Sbjct: 283 RAGLRAPDTQRLYKIASPDDKNHEAVDLLQKLLHFDPDKRISVEEALQHRYLEE 336
>CE29477 [T] KOG0664 Nemo-like MAPK-related serine/threonine protein kinase
Length = 462
Score = 176 bits (445), Expect = 5e-44
Identities = 104/294 (35%), Positives = 164/294 (55%), Gaps = 13/294 (4%)
Query: 17 VGNGTYATVYKGLNKTTGVYVALKEV-KLDSEEGTPSTAIREISLMKELKHDNIVRLFDV 75
+G G + V+ + +G VALK++ + + REI ++ +HDN++ L D+
Sbjct: 74 IGYGAFGVVWSVTDPRSGKRVALKKMPNVFQNLASCKRVFREIKMLSSFRHDNVLSLLDI 133
Query: 76 IHTEN-----KLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGVAFCHE 130
+ N +L ++ E M +DL K + S + L D VK F +Q+L+G+ + H
Sbjct: 134 LQPANPSFFQELYVLTELMQSDLHKIIV------SPQALTPDHVKVFVYQILRGLKYLHT 187
Query: 131 NRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVN-TFSSEVVTLWYRAPDVLMGSRN 189
ILHRD+KP NLL+N+ LK+ DFGLAR + + EVVT +YRAP++LMG+R
Sbjct: 188 ANILHRDIKPGNLLVNSNCILKICDFGLARTWDQRDRLNMTHEVVTQYYRAPELLMGARR 247
Query: 190 YCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQLAKYNPL 249
Y ++DIWS GCI AE++ K LF + EQL++I D +GTP ++ + AK + L
Sbjct: 248 YTGAVDIWSVGCIFAELLQRKILFQAAGPIEQLQMIIDLLGTPSQEAMKYACEGAKNHVL 307
Query: 250 LPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPWFAE 303
D ++L + + + + VDLL LL +PD R+S ++AL H + E
Sbjct: 308 RAGLRAPDTQRLYKIASPDDKNHEAVDLLQKLLHFDPDKRISVEEALQHRYLEE 361
>CE29476 [T] KOG0664 Nemo-like MAPK-related serine/threonine protein kinase
Length = 634
Score = 176 bits (445), Expect = 5e-44
Identities = 104/294 (35%), Positives = 164/294 (55%), Gaps = 13/294 (4%)
Query: 17 VGNGTYATVYKGLNKTTGVYVALKEV-KLDSEEGTPSTAIREISLMKELKHDNIVRLFDV 75
+G G + V+ + +G VALK++ + + REI ++ +HDN++ L D+
Sbjct: 246 IGYGAFGVVWSVTDPRSGKRVALKKMPNVFQNLASCKRVFREIKMLSSFRHDNVLSLLDI 305
Query: 76 IHTEN-----KLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGVAFCHE 130
+ N +L ++ E M +DL K + S + L D VK F +Q+L+G+ + H
Sbjct: 306 LQPANPSFFQELYVLTELMQSDLHKIIV------SPQALTPDHVKVFVYQILRGLKYLHT 359
Query: 131 NRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVN-TFSSEVVTLWYRAPDVLMGSRN 189
ILHRD+KP NLL+N+ LK+ DFGLAR + + EVVT +YRAP++LMG+R
Sbjct: 360 ANILHRDIKPGNLLVNSNCILKICDFGLARTWDQRDRLNMTHEVVTQYYRAPELLMGARR 419
Query: 190 YCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQLAKYNPL 249
Y ++DIWS GCI AE++ K LF + EQL++I D +GTP ++ + AK + L
Sbjct: 420 YTGAVDIWSVGCIFAELLQRKILFQAAGPIEQLQMIIDLLGTPSQEAMKYACEGAKNHVL 479
Query: 250 LPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPWFAE 303
D ++L + + + + VDLL LL +PD R+S ++AL H + E
Sbjct: 480 RAGLRAPDTQRLYKIASPDDKNHEAVDLLQKLLHFDPDKRISVEEALQHRYLEE 533
>Hs7106269 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 452
Score = 175 bits (444), Expect = 6e-44
Identities = 113/293 (38%), Positives = 158/293 (53%), Gaps = 37/293 (12%)
Query: 14 LEKVGNGTYATVYKGLNKTTGVYVALKEVKLDS-EEGTPSTAIREISLMKELKHDN-IVR 71
L ++G G + V+K + TG +ALK+V L E+G P+ A+REI ++E++ + +V+
Sbjct: 7 LGRIGEGAHGIVFKAKHVETGEIIALKKVALRRLEDGFPNQALREIKALQEMEDNQYVVQ 66
Query: 72 LFDVIHTENKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGVAFCHEN 131
L V L FEFM +DL + + + + + L VK + LL+GVAFCH N
Sbjct: 67 LKAVFPHGGGFVLAFEFMLSDLAEVVRH-----AQRPLAQAQVKSYLQMLLKGVAFCHAN 121
Query: 132 RILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGSRNYC 191
I+HRDLKP NLLI+ GQLK+ DFGLAR F +PD GSR Y
Sbjct: 122 NIVHRDLKPANLLISASGQLKIADFGLARVF-----------------SPD---GSRLYT 161
Query: 192 TSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQLAKYNPLLP 251
+ S GCI+ E++ G PLFPG ND EQL + +GTP Q WP++T+L YN +
Sbjct: 162 HQVATRSVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQVWPELTELPDYNKI-- 219
Query: 252 PHMPRDLKQLLQNNTEEVLDD---NVVDLLHGLLQLNPDARLSAKDALNHPWF 301
K+ + EEVL D +DLL L P R++A AL H +F
Sbjct: 220 -----SFKEQVPMPLEEVLPDVSPQALDLLGQFLLYPPHQRIAASKALLHQYF 267
>At3g59790 [T] KOG0660 Mitogen-activated protein kinase
Length = 393
Score = 175 bits (444), Expect = 6e-44
Identities = 102/295 (34%), Positives = 166/295 (55%), Gaps = 11/295 (3%)
Query: 14 LEKVGNGTYATVYKGLNKTTGVYVALKEV-KLDSEEGTPSTAIREISLMKELKHDNIVRL 72
+ +G G V ++ T VA+K++ ++ +REI L++ H+NIV +
Sbjct: 63 IRPIGRGACGIVCSAVDSETNEKVAIKKITQVFDNTIEAKRTLREIKLLRHFDHENIVAI 122
Query: 73 FDVIHTENKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGVAFCHENR 132
DVI + + ++ N+L +F D S + L D YF +Q+L+G+ + H
Sbjct: 123 RDVILPPQRDSFEDVYIVNELMEF-DLYRTLKSDQELTKDHGMYFMYQILRGLKYIHSAN 181
Query: 133 ILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGSRNYCT 192
+LHRDLKP NLL++ + LK+ DFGLARA N + VVT WYRAP++L+GS +Y
Sbjct: 182 VLHRDLKPSNLLLSTQCDLKICDFGLARATP-ESNLMTEYVVTRWYRAPELLLGSSDYTA 240
Query: 193 SIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQLAKYNPLLPP 252
+ID+WS GCI E++ +PLFPG + QL+L+ + +GTP E+ +++ AK P
Sbjct: 241 AIDVWSVGCIFMEIMNREPLFPGKDQVNQLRLLLELIGTPSEEELGSLSEYAKRYIRQLP 300
Query: 253 HMPRDLKQLLQNNTEEV--LDDNVVDLLHGLLQLNPDARLSAKDALNHPWFAEYN 305
+PR Q+ TE+ + +DL+ +L +P R+S K+AL HP+ + ++
Sbjct: 301 TLPR------QSFTEKFPNVPPLAIDLVEKMLTFDPKQRISVKEALAHPYLSSFH 349
>Hs4507281 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 1030
Score = 175 bits (443), Expect = 8e-44
Identities = 105/295 (35%), Positives = 169/295 (56%), Gaps = 12/295 (4%)
Query: 10 RFKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSEEG--TPSTAIREISLMKELKHD 67
+F+ L VG G Y V K +K T VA+K+ K DSEE T +RE+ +++ LK +
Sbjct: 12 KFEILGVVGEGAYGVVLKCRHKETHEIVAIKKFK-DSEENEEVKETTLRELKMLRTLKQE 70
Query: 68 NIVRLFDVIHTENKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGVAF 127
NIV L + KL LVFE+++ ++ + ++ G + + VK + +QL++ + +
Sbjct: 71 NIVELKEAFRRRGKLYLVFEYVEKNMLELLEEMPNG-----VPPEKVKSYIYQLIKAIHW 125
Query: 128 CHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVN-TFSSEVVTLWYRAPDVLMG 186
CH+N I+HRD+KP+NLLI++ LKL DFG AR N ++ V T WYR+P++L+G
Sbjct: 126 CHKNDIVHRDIKPENLLISHNDVLKLCDFGFARNLSEGNNANYTEYVATRWYRSPELLLG 185
Query: 187 SRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQLAKY 246
+ Y S+D+WS GCIL E+ G+PLFPG ++ +QL I +G + ++
Sbjct: 186 A-PYGKSVDMWSVGCILGELSDGQPLFPGESEIDQLFTIQKVLGPLPSEQMKLFYSNPRF 244
Query: 247 NPLLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPWF 301
+ L P + + Q L+ +L+ ++DL+ LL+L+P R + LNHP F
Sbjct: 245 HGLRFPAV--NHPQSLERRYLGILNSVLLDLMKNLLKLDPADRYLTEQCLNHPTF 297
>Hs7706059 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 455
Score = 174 bits (442), Expect = 1e-43
Identities = 95/292 (32%), Positives = 159/292 (53%), Gaps = 10/292 (3%)
Query: 11 FKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPSTAIREISLMKELKHDNIV 70
++ L KVG G+Y TV K +K TG VA+K E+ A+REI +K+ H+N+V
Sbjct: 4 YETLGKVGEGSYGTVMKCKHKNTGQIVAIKIFYERPEQSVNKIAMREIKFLKQFHHENLV 63
Query: 71 RLFDVIHTENKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGVAFCHE 130
L +V + K+ LVFEF+D+ + + + G LE ++ + +Q+L+ + + H
Sbjct: 64 NLIEVFRQKKKIHLVFEFIDHTVLDELQHYCHG-----LESKRLRKYLFQILRAIDYLHS 118
Query: 131 NRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGSRNY 190
N I+HRD+KP+N+L++ G KL DFG AR P + ++ V T WYRAP++++ +Y
Sbjct: 119 NNIIHRDIKPENILVSQSGITKLCDFGFARTLAAPGDIYTDYVATRWYRAPELVLKDTSY 178
Query: 191 CTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQLAKYNPLL 250
+DIW+ GC++ EM G P P S+D + L I +G P + + +P+
Sbjct: 179 GKPVDIWALGCMIIEMATGNPYLPSSSDLDLLHKIVLKVG----NLSPHLQNIFSKSPIF 234
Query: 251 P-PHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPWF 301
+P+ L+ + D++H LQ++P R+S+ D L+H +F
Sbjct: 235 AGVVLPQVQHPKNARKKYPKLNGLLADIVHACLQIDPADRISSSDLLHHEYF 286
>Hs4506785 [T] KOG0660 Mitogen-activated protein kinase
Length = 367
Score = 174 bits (441), Expect = 1e-43
Identities = 108/300 (36%), Positives = 163/300 (54%), Gaps = 24/300 (8%)
Query: 11 FKQLEKVGNGTYATVYKGLNKTTGVYVALKEV-KLDSEEGTPSTAIREISLMKELKHDNI 69
++ L+ VG+G Y V ++ TG VA+K++ + E A RE+ L+K ++H+N+
Sbjct: 27 YRDLQPVGSGAYGAVCSAVDGRTGAKVAIKKLYRPFQSELFAKRAYRELRLLKHMRHENV 86
Query: 70 VRLFDVIHTENKLT------LVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQ 123
+ L DV + L LV FM DL K M H+ L D +++ +Q+L+
Sbjct: 87 IGLLDVFTPDETLDDFTDFYLVMPFMGTDLGKLM-------KHEKLGEDRIQFLVYQMLK 139
Query: 124 GVAFCHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDV 183
G+ + H I+HRDLKP NL +N +LK+ DFGLAR + + VVT WYRAP+V
Sbjct: 140 GLRYIHAAGIIHRDLKPGNLAVNEDCELKILDFGLARQADSEMTGY---VVTRWYRAPEV 196
Query: 184 LMGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQL 243
++ Y ++DIWS GCI+AEMI GK LF GS+ +QLK I GTP + ++
Sbjct: 197 ILNWMRYTQTVDIWSVGCIMAEMITGKTLFKGSDHLDQLKEIMKVTGTPPAEFVQRLQSD 256
Query: 244 AKYNPL--LPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPWF 301
N + LP +D +L N V+LL +L L+ + R++A +AL HP+F
Sbjct: 257 EAKNNMKGLPELEKKDFASILTN-----ASPLAVNLLEKMLVLDAEQRVTAGEALAHPYF 311
>CE12408 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 527
Score = 174 bits (440), Expect = 2e-43
Identities = 97/295 (32%), Positives = 167/295 (55%), Gaps = 16/295 (5%)
Query: 10 RFKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPSTAIREISLMKELKHDNI 69
R+ +++G+GT+ V TG VA+K +K + ++RE+ +K+L H NI
Sbjct: 44 RYLMTKRLGDGTFGEVMLAKKIDTGDRVAIKRMKKKFYSWEEAMSLREVKSLKKLNHPNI 103
Query: 70 VRLFDVIHTENKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGVAFCH 129
++L +VI + L VFEFM +L + M +R++ +++ +Q+LQG+AF H
Sbjct: 104 IKLREVIRENDILYFVFEFMQENLYELMKDRDRY-----FPESVIRNIIYQVLQGLAFMH 158
Query: 130 ENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGSRN 189
+N HRD+KP+N++ N +K+ DFGLAR ++ V T WYRAP++L+ S +
Sbjct: 159 KNGFFHRDMKPENIMCNGTELVKIADFGLAREIRSKP-PYTDYVSTRWYRAPEILLRSTS 217
Query: 190 YCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQLAKYNPL 249
Y + ID+W+ GCI+AE+ + +PLFPG+++ +QL I +GTP + WP+ QLA
Sbjct: 218 YNSPIDMWALGCIMAELYILRPLFPGTSEMDQLFKIISILGTPNKDEWPEGYQLAS---- 273
Query: 250 LPPHMPRDLKQLLQNNTEEV---LDDNVVDLLHGLLQLNPDARLSAKDALNHPWF 301
M +Q++ E+V + + L+ ++ NP+ R +A +L + +F
Sbjct: 274 ---AMNFRFQQVVATPMEQVVNTISKEGMKLMMDMMLWNPEKRPNANQSLRYKYF 325
>Hs4502745 [K] KOG0666 Cyclin C-dependent kinase CDK8
Length = 464
Score = 173 bits (438), Expect = 3e-43
Identities = 104/320 (32%), Positives = 172/320 (53%), Gaps = 40/320 (12%)
Query: 16 KVGNGTYATVYKGLNKT--TGVYVALKEVKLDSEEGTPSTAIREISLMKELKHDNIVRLF 73
KVG GTY VYK K ALK+++ G +A REI+L++ELKH N++ L
Sbjct: 26 KVGRGTYGHVYKAKRKDGKDDKDYALKQIE---GTGISMSACREIALLRELKHPNVISLQ 82
Query: 74 DVI--HTENKLTLVFEFMDNDLKKFMDNRNKGNSHKG---LEMDLVKYFQWQLLQGVAFC 128
V H + K+ L+F++ ++DL + ++K L +VK +Q+L G+ +
Sbjct: 83 KVFLSHADRKVWLLFDYAEHDLWHIIKFHRASKANKKPVQLPRGMVKSLLYQILDGIHYL 142
Query: 129 HENRILHRDLKPQNLLINN----RGQLKLGDFGLARAFGIPVNTFSS---EVVTLWYRAP 181
H N +LHRDLKP N+L+ RG++K+ D G AR F P+ + VVT WYRAP
Sbjct: 143 HANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWYRAP 202
Query: 182 DVLMGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDE---------EQLKLIFDTMGTP 232
++L+G+R+Y +IDIW+ GCI AE++ +P+F ++ +QL IF+ MG P
Sbjct: 203 ELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPYHHDQLDRIFNVMGFP 262
Query: 233 VEQTWPQVTQLAKYNPLLPPHMPRDLKQLLQNNTEEVL---------DDNVVDLLHGLLQ 283
++ W + ++ +++ L+ +D ++ N + D LL LL
Sbjct: 263 ADKDWEDIKKMPEHSTLM-----KDFRRNTYTNCSLIKYMEKHKVKPDSKAFHLLQKLLT 317
Query: 284 LNPDARLSAKDALNHPWFAE 303
++P R++++ A+ P+F E
Sbjct: 318 MDPIKRITSEQAMQDPYFLE 337
>Hs17461944 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 385
Score = 173 bits (438), Expect = 3e-43
Identities = 97/305 (31%), Positives = 172/305 (55%), Gaps = 16/305 (5%)
Query: 10 RFKQLEKVGNGTYATVYKGLNKTTGVYVALKE-VKLDSEEGTPSTAIREISLMKELKHDN 68
++++L K G G+Y V+K NKT+G VA+K+ V+ + + A+REI ++K+LKH N
Sbjct: 3 KYEKLAKTGEGSYGVVFKCRNKTSGQVVAVKKFVESEDDPVVKKIALREIRMLKQLKHPN 62
Query: 69 IVRLFDVIHTENKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGVAFC 128
+V L +V + K+ LVFE+ D+ L ++ + G++ D + +
Sbjct: 63 LVNLIEVFRRKRKMHLVFEYCDHTLLNELER-----NPNGMDSDSIVGRLRSVADRSRLA 117
Query: 129 HEN------RILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPD 182
+N + +HRD+KP+N+LI +G +K+ DFG A+ IP + ++ V T WYRAP+
Sbjct: 118 PKNNQIMILQCIHRDIKPENILITKQGIIKICDFGFAQIL-IPGDAYTDYVATRWYRAPE 176
Query: 183 VLMGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQ 242
+L+G Y +S+DIW+ GC+ AE++ G+PL+PG +D +QL LI T+G + +
Sbjct: 177 LLVGDTQYGSSVDIWAIGCVFAELLTGQPLWPGKSDVDQLYLIIRTLGKLIPRHQSIFKS 236
Query: 243 LAKYNPLLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPWFA 302
++ + P P D++ L + ++ + ++ + G L++NPD RL+ L +F
Sbjct: 237 NGFFHGISIPE-PEDMETLEEKFSD--VHPVALNFMKGCLKMNPDDRLTCSQLLESSYFD 293
Query: 303 EYNHA 307
+ A
Sbjct: 294 SFQEA 298
>At2g46070 [T] KOG0660 Mitogen-activated protein kinase
Length = 406
Score = 172 bits (437), Expect = 4e-43
Identities = 97/301 (32%), Positives = 166/301 (54%), Gaps = 22/301 (7%)
Query: 14 LEKVGNGTYATVYKGLNKTTGVYVALKEV--KLDSEEGTPSTAIREISLMKELKHDNIVR 71
+ +G G V +N TG VA+K++ D+ T +REI L++ + H+N++
Sbjct: 78 IRPIGRGACGIVCAAVNSVTGEKVAIKKIGNAFDNIIDAKRT-LREIKLLRHMDHENVIT 136
Query: 72 LFDVIHTE-----NKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGVA 126
+ D++ N + +V+E MD DL++ + S++ L D ++ +QLL+G+
Sbjct: 137 IKDIVRPPQRDIFNDVYIVYELMDTDLQRIL------RSNQTLTSDQCRFLVYQLLRGLK 190
Query: 127 FCHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMG 186
+ H ILHRDL+P N+L+N++ +LK+GDFGLAR + + VVT WYRAP++L+
Sbjct: 191 YVHSANILHRDLRPSNVLLNSKNELKIGDFGLARTTS-DTDFMTEYVVTRWYRAPELLLN 249
Query: 187 SRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQT--WPQVTQLA 244
Y +IDIWS GCIL E++ G+PLFPG + QL+LI + +G+P + + +
Sbjct: 250 CSEYTAAIDIWSVGCILGEIMTGQPLFPGKDYVHQLRLITELVGSPDNSSLGFLRSDNAR 309
Query: 245 KYNPLLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPWFAEY 304
+Y LP + + + +DLL +L +P+ R+S +AL H + + +
Sbjct: 310 RYVRQLPRYPKQQFAARFPK-----MPTTAIDLLERMLVFDPNRRISVDEALGHAYLSPH 364
Query: 305 N 305
+
Sbjct: 365 H 365
>ECU08g1790 [D] KOG0600 Cdc2-related protein kinase
Length = 309
Score = 172 bits (435), Expect = 7e-43
Identities = 93/287 (32%), Positives = 159/287 (54%), Gaps = 16/287 (5%)
Query: 10 RFKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPSTAIREISLMKELKHDNI 69
+++ +++VG G + VYK + G A+K++ +D E G P TAIREI L K + + +I
Sbjct: 3 KYENIKQVGEGAFGQVYKSRRTSDGAVFAIKKMPVDRETGFPFTAIREIKLCKSVINKHI 62
Query: 70 VRLFDVIHTENKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGVAFCH 129
+ L +++ E + +V E+M DL + + K L D ++ QL++ V+ H
Sbjct: 63 IGLDEIVFEEGFIFVVLEYMPYDLTGLLASGAK------LSTDQIRSITSQLIEAVSSMH 116
Query: 130 ENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGSRN 189
++HRD+KP N+L++ G LKL DFGL R ++ V TLWYRAP++L+G +
Sbjct: 117 GMGLVHRDIKPSNILLDCHGMLKLTDFGLTREIS---GMMTNRVCTLWYRAPELLLGETS 173
Query: 190 YCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQ-TWPQVTQLAKYNP 248
Y +D WS GCI+ EM +G+P + GS++ Q+KLIF+ +G P ++ W + + Y+
Sbjct: 174 YSLKVDAWSVGCIMLEMRLGRPPYRGSDEVSQIKLIFEELGIPQDKYKWSDLLDVDIYS- 232
Query: 249 LLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDA 295
R ++++ + D+ + +L G L L RLS ++
Sbjct: 233 -----KSRSTEEIIAERYGHLFDEEELKVLSGFLCLTSRKRLSVANS 274
>CE23826 [D] KOG0669 Cyclin T-dependent kinase CDK9
Length = 489
Score = 172 bits (435), Expect = 7e-43
Identities = 114/355 (32%), Positives = 178/355 (50%), Gaps = 63/355 (17%)
Query: 3 PLLRYETRFKQLEKVGNGTYATVYKGLN-----------KTTGVYVALKEVKLDSE-EGT 50
P +R + +++L K+G GT+ V +G K TG VALK++ +++E EG
Sbjct: 77 PFIRDVSTYEKLNKIGQGTFGQVLQGRKSRNSEVFKARCKNTGRMVALKKILMENEKEGF 136
Query: 51 PSTAIREISLMKELKHDNIVRLFDVIHTENKLT----------LVFEFMDNDLKKFMDNR 100
P TA+RE+ ++++LKH NI L +V ++ T LV +DL + N
Sbjct: 137 PITALREVKMLEQLKHPNITDLIEVCSAKSTGTTGSKDRATFYLVMALCAHDLAGLLSNP 196
Query: 101 NKGNSHKGLEMDLV--KYFQWQLLQGVAFCHENRILHRDLKPQNLLINNRGQLKLGDFGL 158
+ M LV K L+ G+ H ++ILHRD+K N+LI+ G LKL DFGL
Sbjct: 197 K-------IRMSLVHIKTMMKHLMSGLNKLHRSKILHRDMKAANVLISKDGILKLADFGL 249
Query: 159 ARAF------GIPVNTFSSEVVTLWYRAPDVLMGSRNYCTSIDIWSCGCILAEMIMGKPL 212
AR F P +++ VVTLWYR P++L+G R Y T ID+W GCI+AEM +P+
Sbjct: 250 ARPFVQRENGAGPRPLYTNRVVTLWYRPPELLLGDRQYGTKIDVWGAGCIMAEMWTRQPI 309
Query: 213 FPGSNDEEQLKLIFDTMGTPVEQTWPQVTQL-------AKYNPLLPPH----MPRDLKQL 261
G +++QL+LI G+ + WP + ++ N LP +P +K L
Sbjct: 310 MQGDTEQKQLQLISGLCGSINKDVWPNCVNMPLWSAMSSEPNSALPQGKYRILPNKMKNL 369
Query: 262 LQ---------------NNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPWF 301
++ + DD+ + LL LL ++PD R ++ +A + WF
Sbjct: 370 MKFDAPDSKTDPFGKNVKQHDSATDDDALHLLEILLAIDPDKRPTSDEAEDDIWF 424
>CE18824 [D] KOG0669 Cyclin T-dependent kinase CDK9
Length = 456
Score = 172 bits (435), Expect = 7e-43
Identities = 114/355 (32%), Positives = 178/355 (50%), Gaps = 63/355 (17%)
Query: 3 PLLRYETRFKQLEKVGNGTYATVYKGLN-----------KTTGVYVALKEVKLDSE-EGT 50
P +R + +++L K+G GT+ V +G K TG VALK++ +++E EG
Sbjct: 77 PFIRDVSTYEKLNKIGQGTFGQVLQGRKSRNSEVFKARCKNTGRMVALKKILMENEKEGF 136
Query: 51 PSTAIREISLMKELKHDNIVRLFDVIHTENKLT----------LVFEFMDNDLKKFMDNR 100
P TA+RE+ ++++LKH NI L +V ++ T LV +DL + N
Sbjct: 137 PITALREVKMLEQLKHPNITDLIEVCSAKSTGTTGSKDRATFYLVMALCAHDLAGLLSNP 196
Query: 101 NKGNSHKGLEMDLV--KYFQWQLLQGVAFCHENRILHRDLKPQNLLINNRGQLKLGDFGL 158
+ M LV K L+ G+ H ++ILHRD+K N+LI+ G LKL DFGL
Sbjct: 197 K-------IRMSLVHIKTMMKHLMSGLNKLHRSKILHRDMKAANVLISKDGILKLADFGL 249
Query: 159 ARAF------GIPVNTFSSEVVTLWYRAPDVLMGSRNYCTSIDIWSCGCILAEMIMGKPL 212
AR F P +++ VVTLWYR P++L+G R Y T ID+W GCI+AEM +P+
Sbjct: 250 ARPFVQRENGAGPRPLYTNRVVTLWYRPPELLLGDRQYGTKIDVWGAGCIMAEMWTRQPI 309
Query: 213 FPGSNDEEQLKLIFDTMGTPVEQTWPQVTQL-------AKYNPLLPPH----MPRDLKQL 261
G +++QL+LI G+ + WP + ++ N LP +P +K L
Sbjct: 310 MQGDTEQKQLQLISGLCGSINKDVWPNCVNMPLWSAMSSEPNSALPQGKYRILPNKMKNL 369
Query: 262 LQ---------------NNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPWF 301
++ + DD+ + LL LL ++PD R ++ +A + WF
Sbjct: 370 MKFDAPDSKTDPFGKNVKQHDSATDDDALHLLEILLAIDPDKRPTSDEAEDDIWF 424
>7294866 [K] KOG0666 Cyclin C-dependent kinase CDK8
Length = 531
Score = 172 bits (435), Expect = 7e-43
Identities = 103/316 (32%), Positives = 172/316 (53%), Gaps = 32/316 (10%)
Query: 16 KVGNGTYATVYKGLNKTT--GVYVALKEVKLDSEEGTPSTAIREISLMKELKHDNIVRLF 73
KVG GTY VYK K T G ALK++ G +A REI+L++ELKH N++ L
Sbjct: 103 KVGRGTYGHVYKAKWKETSDGKEYALKQI---DGTGLSMSACREIALLRELKHQNVITLI 159
Query: 74 DVI--HTENKLTLVFEFMDNDLKKFMDNRNKGNSHKG---LEMDLVKYFQWQLLQGVAFC 128
V H + K+ L+ ++ ++DL + + K + +VK +Q+L G+ +
Sbjct: 160 RVFLSHNDRKVFLLIDYAEHDLWHIIKFHRAAKATKKQVVVPRGMVKSLLYQILDGIHYL 219
Query: 129 HENRILHRDLKPQNLLI----NNRGQLKLGDFGLARAFGIPVNTFSS---EVVTLWYRAP 181
H N +LHRDLKP N+L+ N RG++K+ D G AR F P+ + VVT WYRAP
Sbjct: 220 HSNWVLHRDLKPANILVMGDGNERGRVKIADMGFARLFNAPLKPLADLDPVVVTFWYRAP 279
Query: 182 DVLMGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDE---------EQLKLIFDTMGTP 232
++L+G+R+Y +IDIW+ GCI AE++ +P+F ++ +QL IF+ MG P
Sbjct: 280 ELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPYHHDQLDRIFNVMGFP 339
Query: 233 VEQTWPQVTQLAKYNPLL-----PPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPD 287
++ W + ++ +++ L + L + ++ + + D LL LL ++P+
Sbjct: 340 QDKDWEDIKKMPEHHTLTKDFKRSTYSTCSLAKYMERHKIKP-DSKAFHLLQKLLLMDPN 398
Query: 288 ARLSAKDALNHPWFAE 303
R++++ A+ +F E
Sbjct: 399 KRITSEQAMQDQYFQE 414
>At3g45640 [T] KOG0660 Mitogen-activated protein kinase
Length = 370
Score = 171 bits (433), Expect = 1e-42
Identities = 104/302 (34%), Positives = 166/302 (54%), Gaps = 24/302 (7%)
Query: 17 VGNGTYATVYKGLNKTTGVYVALKEVK--LDSEEGTPSTAIREISLMKELKHDNIVRLFD 74
+G G Y V L+ T VA+K++ D+ T +REI L++ L H+NI+ + D
Sbjct: 44 IGRGAYGIVCSVLDTETNELVAMKKIANAFDNHMDAKRT-LREIKLLRHLDHENIIAIRD 102
Query: 75 VIHTE-----NKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGVAFCH 129
V+ + + + E MD DL + + S++ L + +YF +QLL+G+ + H
Sbjct: 103 VVPPPLRRQFSDVYISTELMDTDLHQII------RSNQSLSEEHCQYFLYQLLRGLKYIH 156
Query: 130 ENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSE-VVTLWYRAPDVLMGSR 188
I+HRDLKP NLL+N LK+ DFGLAR N F +E VVT WYRAP++L+ S
Sbjct: 157 SANIIHRDLKPSNLLLNANCDLKICDFGLARPTS--ENDFMTEYVVTRWYRAPELLLNSS 214
Query: 189 NYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQT--WPQVTQLAKY 246
+Y +ID+WS GCI E++ KPLFPG + Q++L+ + +GTP E + +Y
Sbjct: 215 DYTAAIDVWSVGCIFMELMNRKPLFPGKDHVHQMRLLTELLGTPTESDLGFTHNEDAKRY 274
Query: 247 NPLLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPWFAEYNH 306
LP + L +L + ++ +DL+ +L +P+ R++ + ALNH + A+ +
Sbjct: 275 IRQLPNFPRQPLAKLFSH-----VNPMAIDLVDRMLTFDPNRRITVEQALNHQYLAKLHD 329
Query: 307 AN 308
N
Sbjct: 330 PN 331
>Hs20986512 [T] KOG0660 Mitogen-activated protein kinase
Length = 360
Score = 169 bits (429), Expect = 4e-42
Identities = 102/306 (33%), Positives = 169/306 (54%), Gaps = 26/306 (8%)
Query: 10 RFKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPST-AIREISLMKELKHDN 68
R++ L VG+G Y +V + TG+ VA+K++ + + RE+ L+K +KH+N
Sbjct: 23 RYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHEN 82
Query: 69 IVRLFDV------IHTENKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLL 122
++ L DV + N + LV M DL + + + H V++ +Q+L
Sbjct: 83 VIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQKLTDDH-------VQFLIYQIL 135
Query: 123 QGVAFCHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPD 182
+G+ + H I+HRDLKP NL +N +LK+ DFGLAR + + V T WYRAP+
Sbjct: 136 RGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTD---DEMTGYVATRWYRAPE 192
Query: 183 VLMGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQ 242
+++ +Y ++DIWS GCI+AE++ G+ LFPG++ +QLKLI +GTP + +++
Sbjct: 193 IMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPGAELLKKISS 252
Query: 243 LAKYNPLLPPHMPRDLKQLLQNNTEEVL---DDNVVDLLHGLLQLNPDARLSAKDALNHP 299
+ N + + L Q+ + N V + VDLL +L L+ D R++A AL H
Sbjct: 253 ESARNYI------QSLTQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAAQALAHA 306
Query: 300 WFAEYN 305
+FA+Y+
Sbjct: 307 YFAQYH 312
>YLR113w [T] KOG0660 Mitogen-activated protein kinase
Length = 435
Score = 169 bits (428), Expect = 5e-42
Identities = 103/300 (34%), Positives = 156/300 (51%), Gaps = 19/300 (6%)
Query: 10 RFKQLEKVGNGTYATVYKGLNKTTGVYVALKEV-KLDSEEGTPSTAIREISLMKELKHDN 68
R+ L VG G + V + T VA+K++ K S RE+ L+K L+H+N
Sbjct: 22 RYNDLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTAVLAKRTYRELKLLKHLRHEN 81
Query: 69 IVRLFDVIHTE-NKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGVAF 127
++ L D+ + + V E DL + + R LE V+YF +Q+L+G+ +
Sbjct: 82 LICLQDIFLSPLEDIYFVTELQGTDLHRLLQTRP-------LEKQFVQYFLYQILRGLKY 134
Query: 128 CHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGS 187
H ++HRDLKP N+LIN LK+ DFGLAR I + V T +YRAP++++
Sbjct: 135 VHSAGVIHRDLKPSNILINENCDLKICDFGLAR---IQDPQMTGYVSTRYYRAPEIMLTW 191
Query: 188 RNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQV--TQLAK 245
+ Y +DIWS GCI AEMI GKPLFPG + Q +I D +G+P + + K
Sbjct: 192 QKYDVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVINTICSENTLK 251
Query: 246 YNPLLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPWFAEYN 305
+ LP P + + ++ + VDLL +L +P R++A DAL HP+ A Y+
Sbjct: 252 FVTSLPHRDPIPFSERF-----KTVEPDAVDLLEKMLVFDPKKRITAADALAHPYSAPYH 306
>At1g07880 [T] KOG0660 Mitogen-activated protein kinase
Length = 363
Score = 169 bits (428), Expect = 5e-42
Identities = 101/304 (33%), Positives = 159/304 (52%), Gaps = 22/304 (7%)
Query: 14 LEKVGNGTYATVYKGLNKTTGVYVALKEVK--LDSEEGTPSTAIREISLMKELKHDNIVR 71
+E +G G Y V N T VA+K++ D+ T +REI L+ + HDN+++
Sbjct: 36 IEPIGRGAYGIVCCATNSETNEEVAIKKIANAFDNRVDAKRT-LREIKLLSHMDHDNVIK 94
Query: 72 LFDVIHTENK-----LTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGVA 126
+ D+I K + +V+E MD DL + + S + L D +YF +Q+L+G+
Sbjct: 95 IKDIIELPEKERFEDVYIVYELMDTDLHQII------RSTQTLTDDHCQYFLYQILRGLK 148
Query: 127 FCHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMG 186
+ H +LHRDLKP NL++N LK+ DFGLAR + VVT WYRAP++L+
Sbjct: 149 YIHSANVLHRDLKPSNLVLNTNCDLKICDFGLARTSN-ETEIMTEYVVTRWYRAPELLLN 207
Query: 187 SRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQ--TWPQVTQLA 244
S Y +IDIWS GCI E++ + LFPG + +QLKLI + +G+P + + +
Sbjct: 208 SSEYTGAIDIWSVGCIFMEILRRETLFPGKDYVQQLKLITELLGSPDDSDLDFLRSDNAR 267
Query: 245 KYNPLLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPWFAEY 304
KY LP + ++ N + +DL +L +P R++ +AL P+ A
Sbjct: 268 KYVKQLPHVQKQSFREKFPN-----ISPMALDLAEKMLVFDPSKRITVDEALKQPYLASL 322
Query: 305 NHAN 308
+ N
Sbjct: 323 HEIN 326
>7298087 [T] KOG0660 Mitogen-activated protein kinase
Length = 365
Score = 169 bits (428), Expect = 5e-42
Identities = 93/307 (30%), Positives = 167/307 (54%), Gaps = 27/307 (8%)
Query: 11 FKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPST-AIREISLMKELKHDNI 69
++ L+ VG G Y V K + + T VA+K++ + + RE+ L+K + H+N+
Sbjct: 24 YQNLQPVGQGAYGQVCKAVVRGTSTKVAIKKLARPFQSAVHAKRTYRELRLLKHMDHENV 83
Query: 70 VRLFDVIHTEN---------KLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQ 120
+ L DV H ++ +V MD DL + + + H V++ +Q
Sbjct: 84 IGLLDVFHPGQPADSLDQFQQVYMVTHLMDADLNNIIRTQKLSDDH-------VQFLVYQ 136
Query: 121 LLQGVAFCHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRA 180
+L+G+ + H ++HRDLKP N+ +N +L++ DFGLAR + + V T WYRA
Sbjct: 137 ILRGLKYIHSAGVIHRDLKPSNIAVNEDCELRILDFGLARP---AESEMTGYVATRWYRA 193
Query: 181 PDVLMGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQV 240
P++++ +Y + DIWS GCI+AE++ G+ LFPG++ QL LI + +GTP ++ ++
Sbjct: 194 PEIMLNWMHYNQTADIWSVGCIMAELLTGRTLFPGTDHIHQLNLIMEVLGTPADEFMSRI 253
Query: 241 TQLAKYNPL--LPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNH 298
+ + N + LP R+ + + + + +DLL +L+L+ D R++A+ AL H
Sbjct: 254 SSESARNYIRSLPVMPRRNFRDIFRG-----ANPLAIDLLEKMLELDADKRITAEQALAH 308
Query: 299 PWFAEYN 305
P+ +Y+
Sbjct: 309 PYMEKYH 315
>Hs4506085 [T] KOG0660 Mitogen-activated protein kinase
Length = 365
Score = 168 bits (425), Expect = 1e-41
Identities = 105/299 (35%), Positives = 161/299 (53%), Gaps = 29/299 (9%)
Query: 17 VGNGTYATVYKGLNKTTGVYVALKEVKLDSE-EGTPSTAIREISLMKELKHDNIVRLFDV 75
VG+G Y +V ++K +G VA+K++ + E A RE+ L+K ++H+N++ L DV
Sbjct: 31 VGSGAYGSVCSAIDKRSGEKVAIKKLSRPFQSEIFAKRAYRELLLLKHMQHENVIGLLDV 90
Query: 76 IHTENKLT------LVFEFMDNDLKKFMDNRNKGNSHKGLEM--DLVKYFQWQLLQGVAF 127
+ L LV FM DL+K M G+E + ++Y +Q+L+G+ +
Sbjct: 91 FTPASSLRNFYDFYLVMPFMQTDLQKIM----------GMEFSEEKIQYLVYQMLKGLKY 140
Query: 128 CHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGS 187
H ++HRDLKP NL +N +LK+ DFGLAR + + VVT WYRAP+V++
Sbjct: 141 IHSAGVVHRDLKPGNLAVNEDCELKILDFGLARHADAEMTGY---VVTRWYRAPEVILSW 197
Query: 188 RNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQLA--K 245
+Y ++DIWS GCI+AEM+ GK LF G + +QL I G P + ++ A
Sbjct: 198 MHYNQTVDIWSVGCIMAEMLTGKTLFKGKDYLDQLTQILKVTGVPGTEFVQKLNDKAAKS 257
Query: 246 YNPLLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPWFAEY 304
Y LP +D QL + + DLL +L+L+ D RL+A AL HP+F +
Sbjct: 258 YIQSLPQTPRKDFTQLFPRASPQ-----AADLLEKMLELDVDKRLTAAQALTHPFFEPF 311
>Hs7706445 [T] KOG0664 Nemo-like MAPK-related serine/threonine protein kinase
Length = 515
Score = 167 bits (423), Expect = 2e-41
Identities = 106/294 (36%), Positives = 161/294 (54%), Gaps = 15/294 (5%)
Query: 17 VGNGTYATVYKGLNKTTGVYVALKEV-KLDSEEGTPSTAIREISLMKELKHDNIVRLFDV 75
+G G + V+ + G VALK++ + + RE+ ++ KHDN++ D+
Sbjct: 132 IGYGAFGVVWSVTDPRDGKRVALKKMPNVFQNLVSCKRVFRELKMLCFFKHDNVLSALDI 191
Query: 76 IHTEN-----KLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGVAFCHE 130
+ + ++ +V E M +DL K + S + L D VK F +Q+L+G+ + H
Sbjct: 192 LQPPHIDYFEEIYVVTELMQSDLHKIIV------SPQPLSSDHVKVFLYQILRGLKYLHS 245
Query: 131 NRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNT-FSSEVVTLWYRAPDVLMGSRN 189
ILHRD+KP NLL+N+ LK+ DFGLAR + + + EVVT +YRAP++LMGSR+
Sbjct: 246 AGILHRDIKPGNLLVNSNCVLKICDFGLARVEELDESRHMTQEVVTQYYRAPEILMGSRH 305
Query: 190 YCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQLAKYNPL 249
Y +IDIWS GCI AE++ + LF + +QL LI D +GTP + + AK + L
Sbjct: 306 YSNAIDIWSVGCIFAELLGRRILFQAQSPIQQLDLITDLLGTPSLEAMRTACEGAKAHIL 365
Query: 250 LPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPWFAE 303
PH L L +++ V LL +L +P R+SAKDAL HP+ E
Sbjct: 366 RGPHKQPSLPVLYTLSSQAT--HEAVHLLCRMLVFDPSKRISAKDALAHPYLDE 417
>Hs4506091 [T] KOG0660 Mitogen-activated protein kinase
Length = 721
Score = 167 bits (423), Expect = 2e-41
Identities = 105/318 (33%), Positives = 169/318 (53%), Gaps = 36/318 (11%)
Query: 9 TRFKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPSTAIREISLMKELKHDN 68
+R+ L+ +G G V+ ++ VA+K++ L + A+REI +++ L HDN
Sbjct: 18 SRYMDLKPLGCGGNGLVFSAVDNDCDKRVAIKKIVLTDPQSVKH-ALREIKIIRRLDHDN 76
Query: 69 IVRLFDVIHTE--------------NKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLV 114
IV++F+++ N + +V E+M+ DL ++ H L
Sbjct: 77 IVKVFEILGPSGSQLTDDVGSLTELNSVYIVQEYMETDLANVLEQGPLLEEHARL----- 131
Query: 115 KYFQWQLLQGVAFCHENRILHRDLKPQNLLINNRGQ-LKLGDFGLARAFGIPVNT---FS 170
F +QLL+G+ + H +LHRDLKP NL IN LK+GDFGLAR + S
Sbjct: 132 --FMYQLLRGLKYIHSANVLHRDLKPANLFINTEDLVLKIGDFGLARIMDPHYSHKGHLS 189
Query: 171 SEVVTLWYRAPDVLMGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMG 230
+VT WYR+P +L+ NY +ID+W+ GCI AEM+ GK LF G+++ EQ++LI +++
Sbjct: 190 EGLVTKWYRSPRLLLSPNNYTKAIDMWAAGCIFAEMLTGKTLFAGAHELEQMQLILESIP 249
Query: 231 TPVEQTWPQVTQLAKY---NPLLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPD 287
E+ ++ + N + PH P L QLL + E L D L +L +P
Sbjct: 250 VVHEEDRQELLSVIPVYIRNDMTEPHKP--LTQLLPGISREAL-----DFLEQILTFSPM 302
Query: 288 ARLSAKDALNHPWFAEYN 305
RL+A++AL+HP+ + Y+
Sbjct: 303 DRLTAEEALSHPYMSIYS 320
>Hs20128774 [T] KOG0660 Mitogen-activated protein kinase
Length = 364
Score = 166 bits (421), Expect = 3e-41
Identities = 101/305 (33%), Positives = 166/305 (54%), Gaps = 24/305 (7%)
Query: 10 RFKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPST-AIREISLMKELKHDN 68
R + L VG+G Y +V + VA+K++ + + RE+ L+K LKH+N
Sbjct: 23 RLQGLRPVGSGAYGSVCSAYDARLRQKVAVKKLSRPFQSLIHARRTYRELRLLKHLKHEN 82
Query: 69 IVRLFDV------IHTENKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLL 122
++ L DV I +++ LV M DL + + + H V++ +QLL
Sbjct: 83 VIGLLDVFTPATSIEDFSEVYLVTTLMGADLNNIVKCQALSDEH-------VQFLVYQLL 135
Query: 123 QGVAFCHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPD 182
+G+ + H I+HRDLKP N+ +N +L++ DFGLAR + + V T WYRAP+
Sbjct: 136 RGLKYIHSAGIIHRDLKPSNVAVNEDCELRILDFGLARQADEEMTGY---VATRWYRAPE 192
Query: 183 VLMGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVT- 241
+++ +Y ++DIWS GCI+AE++ GK LFPGS+ +QLK I + +GTP + +++
Sbjct: 193 IMLNWMHYNQTVDIWSVGCIMAELLQGKALFPGSDYIDQLKRIMEVVGTPSPEVLAKISS 252
Query: 242 -QLAKYNPLLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPW 300
Y LPP +DL + + + +DLL +L L+ D R+SA +AL H +
Sbjct: 253 EHARTYIQSLPPMPQKDLSSIFRG-----ANPLAIDLLGRMLVLDSDQRVSAAEALAHAY 307
Query: 301 FAEYN 305
F++Y+
Sbjct: 308 FSQYH 312
>At4g11330 [T] KOG0660 Mitogen-activated protein kinase
Length = 373
Score = 164 bits (415), Expect = 1e-40
Identities = 95/280 (33%), Positives = 156/280 (54%), Gaps = 20/280 (7%)
Query: 37 VALKEV-KLDSEEGTPSTAIREISLMKELKHDNIVRLFDVIHTENK-----LTLVFEFMD 90
+A+K++ K + +REI L++ L+H+N+V + D+I K + +VFE MD
Sbjct: 66 IAIKKIGKAFDNKVDAKRTLREIKLLRHLEHENVVVIKDIIRPPKKEDFVDVYIVFELMD 125
Query: 91 NDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGVAFCHENRILHRDLKPQNLLINNRGQ 150
DL + + S++ L D +YF +Q+L+G+ + H +LHRDLKP NLL+N+
Sbjct: 126 TDLHQII------RSNQSLNDDHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNSNCD 179
Query: 151 LKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGSRNYCTSIDIWSCGCILAEMIMGK 210
LK+ DFGLAR + VVT WYRAP++L+ S Y ++ID+WS GCI AE++ +
Sbjct: 180 LKITDFGLARTTS-ETEYMTEYVVTRWYRAPELLLNSSEYTSAIDVWSVGCIFAEIMTRE 238
Query: 211 PLFPGSNDEEQLKLIFDTMGTP--VEQTWPQVTQLAKYNPLLPPHMPRDLKQLLQNNTEE 268
PLFPG + QLKLI + +G+P + + KY LP ++ +
Sbjct: 239 PLFPGKDYVHQLKLITELIGSPDGASLEFLRSANARKYVKELPKFPRQNFSARFPS---- 294
Query: 269 VLDDNVVDLLHGLLQLNPDARLSAKDALNHPWFAEYNHAN 308
++ +DLL +L +P R++ ++AL +P+ + + N
Sbjct: 295 -MNSTAIDLLEKMLVFDPVKRITVEEALCYPYLSALHDLN 333
>CE11556 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 305
Score = 163 bits (413), Expect = 3e-40
Identities = 102/310 (32%), Positives = 155/310 (49%), Gaps = 46/310 (14%)
Query: 2 SPLLRYETRFKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPSTAIREISLM 61
S + RYET ++ G G + V + T VA+K + + + + REIS +
Sbjct: 3 SSIYRYET----IQVAGRGAFGLVVIARDTLTSKRVAIKRIMVPNVSKV--SLAREISCL 56
Query: 62 KELKHDNIVRLFDVIHTENKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQL 121
+ L H NI++L D + + +++V E E+ Y+ Q+
Sbjct: 57 RNLHHRNILKLLDCFPSADLMSIVTE----------------------EVPYTWYYT-QI 93
Query: 122 LQGVAFCHENRILHRDLKPQNLLINNRGQLKLGDFGLARAF--GIPVNTFSSEVVTLWYR 179
L G+A+ H I+HRD+KP+N+L+ +R +K+ DFG A + P + V T WYR
Sbjct: 94 LSGIAYLHSKEIMHRDIKPENILVTSRNVVKIADFGQACFYMPKDPNQEYDVNVATRWYR 153
Query: 180 APDVLMGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQ 239
AP++L GS+ Y +DIW+ GCILAE++ GKP+FPG ++ EQ+ +IF +GTP E WP
Sbjct: 154 APELLFGSKKYKPDVDIWAIGCILAELVRGKPIFPGRSELEQISIIFGVLGTPNEDNWPN 213
Query: 240 VTQLAKYNPLL-PPHMPRDLKQLLQNNTEEVL-----DDNVVDLLHGLLQLNPDARLSAK 293
+ N LL P PR NN E+L +N + L LQ RL A
Sbjct: 214 WRTMPDANKLLFEPKEPR-------NNWTEILLCKEISNNFTEFLGSHLQF--FKRLKAS 264
Query: 294 DALNHPWFAE 303
+ L PW +
Sbjct: 265 ELLKEPWIKQ 274
>CE06686 [T] KOG0660 Mitogen-activated protein kinase
Length = 377
Score = 163 bits (413), Expect = 3e-40
Identities = 99/301 (32%), Positives = 156/301 (50%), Gaps = 24/301 (7%)
Query: 14 LEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPST-AIREISLMKELKHDNIVRL 72
L +G G Y TV +G VA+K+ + + RE+ L++ + H+NI+ L
Sbjct: 38 LTPIGTGAYGTVCAAECTRSGTRVAIKKFNRPFQSIIHARRTYRELRLLRCMCHENIIDL 97
Query: 73 FDVIHTENKLT------LVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGVA 126
DV + V M DL + + + H +++ +Q+L+G+
Sbjct: 98 LDVFTPNENVNDIEDVYFVSMLMGADLSNILKIQRLNDDH-------IQFLVYQILRGLK 150
Query: 127 FCHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMG 186
+ H I+HRDLKP N+ +N +LK+ DFGLAR + + V T WYRAP++++
Sbjct: 151 YIHSADIIHRDLKPSNIAVNEDCELKILDFGLARQTDSEMTGY---VATRWYRAPEIMLN 207
Query: 187 SRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVT--QLA 244
+Y ++D+WS GCILAE+I GK LFPGS+ +QL I GTP E+ +++ +
Sbjct: 208 WMHYTQTVDVWSVGCILAELITGKTLFPGSDHIDQLTRIMSVTGTPDEEFLKKISSEEAR 267
Query: 245 KYNPLLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPWFAEY 304
Y LP RD K+L T + +DLL +L L+PD R +AK+A+ H + A Y
Sbjct: 268 NYIRNLPKMTRRDFKRLFAQATPQ-----AIDLLEKMLHLDPDRRPTAKEAMEHEYLAAY 322
Query: 305 N 305
+
Sbjct: 323 H 323
>CE02602_1 [T] KOG0660 Mitogen-activated protein kinase
Length = 342
Score = 163 bits (413), Expect = 3e-40
Identities = 97/311 (31%), Positives = 164/311 (52%), Gaps = 30/311 (9%)
Query: 9 TRFKQLEKVGNGTYATVYKGLNKTTGVYVALKEV-KLDSEEGTPSTAIREISLMKELKHD 67
T++ E +G G + V + ++ VA+K++ ++ + T A+REI + +EL H+
Sbjct: 42 TQYLAQENLGAGAFGVVCRAIDSKLNKQVAIKKITRVFKNQSTAKCALREIRITRELSHE 101
Query: 68 NIVRLFDVIHTEN----KLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQ 123
NI+ DV+ E+ + +V + M+ DL + S++ L +YF +Q+L+
Sbjct: 102 NIINSTDVLMRESGSGQDIYIVMDLMETDLLSVL------KSNQTLNEKHFQYFFYQILK 155
Query: 124 GVAFCHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNT------------FSS 171
G+ + H I+HRDLKP NLL+N LK+ DFG++R+ T S
Sbjct: 156 GLKYLHSAGIIHRDLKPANLLLNEDCSLKIADFGMSRSGPSTKTTPNTSPNAHISGDLSQ 215
Query: 172 EVVTLWYRAPDVLMGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGT 231
V TLWYRAP++L+ Y T +DIWS GCILAEM++ +P+F G++ Q++L+ + +GT
Sbjct: 216 YVSTLWYRAPEILLSMGEYDTQVDIWSAGCILAEMLLLRPIFTGTDSYSQIQLLIEYLGT 275
Query: 232 PVEQTWPQV--TQLAKYNPLLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDAR 289
P EQ ++ + Y P P + N + E +++ +LQ++P R
Sbjct: 276 PDEQVIRRIKSPSIRDYISSFGPKTPLPFTAMFPNASIEAR-----NIVSKMLQISPWKR 330
Query: 290 LSAKDALNHPW 300
SA+ L P+
Sbjct: 331 FSAEQLLEEPF 341
>SPBC8D2.01 [G] KOG0658 Glycogen synthase kinase-3
Length = 381
Score = 163 bits (412), Expect = 3e-40
Identities = 99/301 (32%), Positives = 162/301 (52%), Gaps = 24/301 (7%)
Query: 17 VGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPSTAIREISLMKELKHDNIVRLFDVI 76
+G+G++ V + T ++A+K V D RE+ +M+ + H NI++L
Sbjct: 31 LGSGSFGVVIQAKLVGTPGFIAVKRVLQDKRYKN-----RELQIMRAISHPNIIKLIAFF 85
Query: 77 HTENK------LTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGVAFCHE 130
HT N L L+ E+M + F D R K + +K + +QL + +A+ H
Sbjct: 86 HTHNPSKDETHLCLLLEYMPETV--FDDMRWYTRRRKSIPNLSIKLYAFQLFRALAYLHS 143
Query: 131 NRILHRDLKPQNLLINNR-GQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGSRN 189
+ HRD+KPQNLL++ + G LKL DFG A+ +P S + + +YRAP+++ G+ +
Sbjct: 144 TGVCHRDIKPQNLLVDYKTGILKLCDFGSAKVL-VPSEPNVSYICSRYYRAPELVFGATH 202
Query: 190 YCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQLAK--YN 247
Y T ID+WS C++AE+ +G+PLFPG + EQL I +GTP ++ +++ + N
Sbjct: 203 YTTKIDVWSAACVIAELFIGRPLFPGDSSVEQLVEIIRVLGTP---SYHEISVMNPNYVN 259
Query: 248 PLLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPWFAEYNHA 307
LP P L+ ++ +N + N +DLLH +L P R+SA + L HP+F E
Sbjct: 260 HSLPNVRPHTLESVMPHNCTK----NAMDLLHKMLTYVPSKRISAIEVLTHPFFDELRDP 315
Query: 308 N 308
N
Sbjct: 316 N 316
>ECU11g0960 [D] KOG0600 Cdc2-related protein kinase
Length = 329
Score = 162 bits (409), Expect = 7e-40
Identities = 90/292 (30%), Positives = 162/292 (54%), Gaps = 17/292 (5%)
Query: 11 FKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPSTAIREISLMKELKHDNIV 70
++++ +G GT+ V L + ALK+V + +EG T IRE+ +++ + H +IV
Sbjct: 22 YEKIRIIGEGTFGQVI--LARKGRARYALKKVSKE-KEGLSVTTIREVQVLRAMGHPSIV 78
Query: 71 RLFDVI-HTENKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGVAFCH 129
RL +V+ + +VF + DL +F+ + S +K+ +Q+ QGV + H
Sbjct: 79 RLIEVVVEPGGDIYMVFPYFPYDLNRFIRSNKMTCSE-------IKHIFYQIAQGVCYIH 131
Query: 130 ENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGSRN 189
I+HRDLK N+L++ + + DFG+AR + ++ +VTLWYRAP++L+GS +
Sbjct: 132 SKGIMHRDLKSANILLDQKLNASIADFGMAR-YTTKTGAYTPGMVTLWYRAPEILLGSSS 190
Query: 190 YCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQLAKYNPL 249
Y ++DIWS GCIL EM +G +F GS + QL+++ G+ E ++P V L +
Sbjct: 191 YTYAVDIWSLGCILTEMYLGHMIFQGSTEMLQLEMVIHACGSINENSYPGVQDLPGFRNF 250
Query: 250 LPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPWF 301
P PR ++ +++ + D + V+L+ +L L+P R++ + + +F
Sbjct: 251 RLPQSPRRIEGIIRKH-----DASAVELVSKMLCLDPSKRITVEQVVGSKYF 297
>YPL042c [K] KOG0666 Cyclin C-dependent kinase CDK8
Length = 555
Score = 161 bits (408), Expect = 1e-39
Identities = 92/296 (31%), Positives = 161/296 (54%), Gaps = 23/296 (7%)
Query: 29 LNKTTGVYVALKEVKLDSE-------EGTPSTAIREISLMKELKHDNIVRLFDVIHTENK 81
+ K V+ A+K+ K + + G +A RE++L +EL + ++ L ++
Sbjct: 172 IKKPLTVFYAIKKFKTEKDGVEQLHYTGISQSACREMALCRELHNKHLTTLVEIFLERKC 231
Query: 82 LTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGVAFCHENRILHRDLKPQ 141
+ +V+E+ ++DL + + + + +V+ WQLL GV++ H+N +LHRDLKP
Sbjct: 232 VHMVYEYAEHDLLQIIHFHSHPEKRM-IPPRMVRSIMWQLLDGVSYLHQNWVLHRDLKPA 290
Query: 142 NLLINNRGQLKLGDFGLARAFGIPVNTF---SSEVVTLWYRAPDVLMGSRNYCTSIDIWS 198
N+++ G +K+GD GLAR F + T VVT+WYRAP++L+G+R+Y ++D+WS
Sbjct: 291 NIMVTIDGCVKIGDLGLARKFHNMLQTLYTGDKVVVTIWYRAPELLLGARHYTPAVDLWS 350
Query: 199 CGCILAEMIMGKPLFPGSNDE-----------EQLKLIFDTMGTPVEQTWPQVTQLAKYN 247
GCI AE+I +P+F G + QL+ I + +GTP ++ WP + + +Y+
Sbjct: 351 VGCIFAELIGLQPIFKGEEAKLDSKKTVPFQVNQLQRILEVLGTPDQKIWPYLEKYPEYD 410
Query: 248 PLLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPWFAE 303
+ RD ++ D + + LL+ LL +P R+ A +AL H +F E
Sbjct: 411 QITKFPKYRD-NLATWYHSAGGRDKHALSLLYHLLNYDPIKRIDAFNALEHKYFTE 465
>Hs4503069 [T] KOG0660 Mitogen-activated protein kinase
Length = 360
Score = 161 bits (407), Expect = 1e-39
Identities = 103/310 (33%), Positives = 164/310 (52%), Gaps = 34/310 (10%)
Query: 10 RFKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPST-AIREISLMKELKHDN 68
R++ L VG+G Y +V + TG+ VA+K++ + + RE+ L+K +KH+N
Sbjct: 23 RYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHEN 82
Query: 69 IVRLFDV------IHTENKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLL 122
++ L DV + N + LV M DL + + + H V++ +Q+L
Sbjct: 83 VIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQKLTDDH-------VQFLIYQIL 135
Query: 123 QGVAFCHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPD 182
+G+ + H I+HRDLKP NL +N +LK+ DFGLAR + + V T WYRAP+
Sbjct: 136 RGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTD---DEMTGYVATRWYRAPE 192
Query: 183 VLMGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQ 242
+++ +Y ++DIWS GCI+AE++ G+ LFPG++ QL+ I GTP
Sbjct: 193 IMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHINQLQQIMRLTGTPP--------- 243
Query: 243 LAKYNPLLPPHMPRD----LKQLLQNNTEEVL---DDNVVDLLHGLLQLNPDARLSAKDA 295
A +P H R+ L Q+ + N V + VDLL +L L+ D R++A A
Sbjct: 244 -AYLINRMPSHEARNYIQSLTQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAAQA 302
Query: 296 LNHPWFAEYN 305
L H +FA+Y+
Sbjct: 303 LAHAYFAQYH 312
>CE17815 [K] KOG0666 Cyclin C-dependent kinase CDK8
Length = 622
Score = 160 bits (406), Expect = 2e-39
Identities = 101/323 (31%), Positives = 172/323 (52%), Gaps = 32/323 (9%)
Query: 11 FKQLEKVGNGTYATVYKGLNKTTGVYVALKE--VKLDSEEGTPSTAIREISLMKELKHDN 68
F+ +++G GTY VYK + K KE +K+ +G +A REI+L +EL+H N
Sbjct: 26 FENSKEIGRGTYGLVYKAVPKKQNGQFPNKEYALKMIEGQGFSMSACREIALFRELRHPN 85
Query: 69 IVRLFDVIHT-ENKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEM---DLVKYFQWQLLQG 124
++ L V T E K+ L+ ++ ++DL + + S K M ++VK +Q+L G
Sbjct: 86 LICLQRVFLTNEKKVWLLLDYAEHDLWHVIKHHRTAKSKKVPIMVPRNMVKNILFQILSG 145
Query: 125 VAFCHENRILHRDLKPQNLLI------NNRGQLKLGDFGLARAFGIPVNTFSS---EVVT 175
+ + H N +LHRDLKP N+L+ + RG++K+ D G +R + P+ + VVT
Sbjct: 146 MHYLHSNWVLHRDLKPANILLMGDGPPDMRGRVKIADLGFSRIYANPLKPMAELDPVVVT 205
Query: 176 LWYRAPDVLMGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDE---------EQLKLIF 226
WYRAP++L+G+++Y +ID+W+ GCI AE++ +PLF ++ +Q+K IF
Sbjct: 206 FWYRAPELLLGAKHYTKAIDVWAIGCIFAELLTAEPLFFCKEEDIKAQNPYHYDQVKRIF 265
Query: 227 DTMGTPVEQTWPQVTQLAKYNPLLPPHMPRDLK-QLLQNNTEEVLDDNVVD-------LL 278
+G P + WP + ++ + LL Q N+ D ++ LL
Sbjct: 266 HLLGYPSDADWPDMKKMPDHQRLLSDARNEGTPIQTFPNSLHRYFDKWKINSQSSPYRLL 325
Query: 279 HGLLQLNPDARLSAKDALNHPWF 301
LL ++P R+S ++A+N +F
Sbjct: 326 VKLLTVDPTKRVSCEEAMNDIYF 348
>At5g45430 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 530
Score = 160 bits (405), Expect = 2e-39
Identities = 94/300 (31%), Positives = 164/300 (54%), Gaps = 19/300 (6%)
Query: 10 RFKQLEKVGNGTYATVYKGLNKTTG--------VYVALKEVKLDSEEGTPSTAIREISLM 61
R+ L++VG+GT+ V++ +NK T V VA+K +K +RE+ +
Sbjct: 3 RYTLLKEVGDGTFGNVWRAVNKQTNEVGTEVFYVQVAIKRMKKKYFSWEECVNLREVKSL 62
Query: 62 KELKHDNIVRLFDVIHTENKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQL 121
+ H NIV+L +VI + L VFE+M+ +L + M +R K + ++ + +Q+
Sbjct: 63 SRMNHPNIVKLKEVIRENDILYFVFEYMECNLYQLMKDRPKHFAESD-----IRNWCFQV 117
Query: 122 LQGVAFCHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAP 181
QG+++ H+ HRDLKP+NLL++ + +K+ D GLAR ++ V T WYRAP
Sbjct: 118 FQGLSYMHQRGYFHRDLKPENLLVS-KDVIKIADLGLAREIDSSP-PYTEYVSTRWYRAP 175
Query: 182 DVLMGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVT 241
+VL+ S Y + +D+W+ G I+AE++ +PLFPG+++ +++ I +G+P E+TW +
Sbjct: 176 EVLLQSYVYTSKVDMWAMGAIMAELLSLRPLFPGASEADEIYKICSVIGSPTEETWLEGL 235
Query: 242 QLAKYNPLLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPWF 301
LA P P + ++ + V+L+ L +P R + +AL HP+F
Sbjct: 236 NLASVINYQFPQFP----GVHLSSVMPYASADAVNLIERLCSWDPCNRPTTAEALQHPFF 291
>Hs4506089 [T] KOG0660 Mitogen-activated protein kinase
Length = 557
Score = 160 bits (404), Expect = 3e-39
Identities = 98/311 (31%), Positives = 165/311 (52%), Gaps = 28/311 (9%)
Query: 10 RFKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPSTAIREISLMKELKHDNI 69
RF + +G G V ++ VA+K++ L S+ + A+REI +++ L HDNI
Sbjct: 19 RFVDFQPLGFGVNGLVLSAVDSRACRKVAVKKIAL-SDARSMKHALREIKIIRRLDHDNI 77
Query: 70 VRLFDVIHTENK-----------LTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQ 118
V++++V+ + +V E+M+ DL + ++ H K F
Sbjct: 78 VKVYEVLGPKGTDLQGELFKFSVAYIVQEYMETDLARLLEQGTLAEEH-------AKLFM 130
Query: 119 WQLLQGVAFCHENRILHRDLKPQNLLINNRGQ-LKLGDFGLARAFGIPVNT---FSSEVV 174
+QLL+G+ + H +LHRDLKP N+ I+ LK+GDFGLAR + S +V
Sbjct: 131 YQLLRGLKYIHSANVLHRDLKPANIFISTEDLVLKIGDFGLARIVDQHYSHKGYLSEGLV 190
Query: 175 TLWYRAPDVLMGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVE 234
T WYR+P +L+ NY +ID+W+ GCILAEM+ G+ LF G+++ EQ++LI +T+ E
Sbjct: 191 TKWYRSPRLLLSPNNYTKAIDMWAAGCILAEMLTGRMLFAGAHELEQMQLILETIPVIRE 250
Query: 235 QTWPQVTQLAKYNPLLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKD 294
+ ++ ++ + R L++LL ++ +D L +L NP RL+A+
Sbjct: 251 EDKDELLRVMPSFVSSTWEVKRPLRKLLPE-----VNSEAIDFLEKILTFNPMDRLTAEM 305
Query: 295 ALNHPWFAEYN 305
L HP+ + Y+
Sbjct: 306 GLQHPYMSPYS 316
>At2g42880 [T] KOG0660 Mitogen-activated protein kinase
Length = 594
Score = 159 bits (402), Expect = 5e-39
Identities = 111/305 (36%), Positives = 167/305 (54%), Gaps = 25/305 (8%)
Query: 10 RFKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPSTAI-REISLMKELKHDN 68
RFK E +G G+Y V ++ TG VA+K++ E + + I REI L++ L+H +
Sbjct: 12 RFKVQEVIGKGSYGVVCSAIDTLTGEKVAIKKIHDIFEHISDAARILREIKLLRLLRHPD 71
Query: 69 IVRLFDVIHTENK-----LTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQ 123
IV + ++ ++ + +VFE M++DL + + ++ L + ++F +QLL+
Sbjct: 72 IVEIKHIMLPPSRREFKDIYVVFELMESDLHQVI------KANDDLTREHYQFFLYQLLR 125
Query: 124 GVAFCHENRILHRDLKPQNLLINNRGQLKLGDFGLAR-AFG-IPVNTFSSE-VVTLWYRA 180
+ + H + HRDLKP+N+L N +LK+ DFGLAR AF P F ++ V T WYRA
Sbjct: 126 ALKYIHTANVYHRDLKPKNILANANCKLKICDFGLARVAFNDTPTTIFWTDYVATRWYRA 185
Query: 181 PDVLMGS--RNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWP 238
P+ L GS Y +IDIWS GCI AE++MGKPLFPG N QL L+ D +GTP T
Sbjct: 186 PE-LCGSFYSKYTPAIDIWSIGCIFAEVLMGKPLFPGKNVVHQLDLMTDLLGTPSLDTIS 244
Query: 239 QV--TQLAKYNPLLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDAL 296
+V + +Y + P Q N D + LL LL +P R +A++AL
Sbjct: 245 RVRNEKARRYLTSMRKKPPIPFAQKFPN-----ADPLSLKLLERLLAFDPKDRPTAEEAL 299
Query: 297 NHPWF 301
P+F
Sbjct: 300 ADPYF 304
>At1g18150 [T] KOG0660 Mitogen-activated protein kinase
Length = 589
Score = 159 bits (402), Expect = 5e-39
Identities = 107/306 (34%), Positives = 167/306 (53%), Gaps = 25/306 (8%)
Query: 10 RFKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPSTAI-REISLMKELKHDN 68
R++ E VG G+Y V ++ TG VA+K++ E + +T I REI L++ L+H +
Sbjct: 103 RYQIQEVVGKGSYGVVASAVDSHTGERVAIKKINDVFEHVSDATRILREIKLLRLLRHPD 162
Query: 69 IVRLFDVIHTENK-----LTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQ 123
+V + ++ ++ + +VFE M++DL + + ++ L + ++F +QLL+
Sbjct: 163 VVEIKHIMLPPSRREFRDIYVVFELMESDLHQVI------KANDDLTPEHYQFFLYQLLR 216
Query: 124 GVAFCHENRILHRDLKPQNLLINNRGQLKLGDFGLARAF--GIPVNTFSSE-VVTLWYRA 180
G+ + H + HRDLKP+N+L N +LK+ DFGLAR P F ++ V T WYRA
Sbjct: 217 GLKYVHAANVFHRDLKPKNILANADCKLKICDFGLARVSFNDAPTAIFWTDYVATRWYRA 276
Query: 181 PDVLMGS--RNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWP 238
P+ L GS Y +IDIWS GCI AEM++GKPLFPG N QL L+ D +GTP ++
Sbjct: 277 PE-LCGSFFSKYTPAIDIWSVGCIFAEMLLGKPLFPGKNVVHQLDLMTDFLGTPPPESIS 335
Query: 239 QV--TQLAKYNPLLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDAL 296
++ + +Y + P D + LL LL +P R SA+DAL
Sbjct: 336 RIRNEKARRYLSSMRKKQPVPFSHKFPK-----ADPLALRLLERLLAFDPKDRASAEDAL 390
Query: 297 NHPWFA 302
P+F+
Sbjct: 391 ADPYFS 396
>CE29020 [T] KOG0660 Mitogen-activated protein kinase
Length = 470
Score = 159 bits (401), Expect = 6e-39
Identities = 96/310 (30%), Positives = 163/310 (51%), Gaps = 23/310 (7%)
Query: 10 RFKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPST-AIREISLMKEL-KHD 67
+F +++G G Y V+K +K + VALK++ T S RE+ ++E KH
Sbjct: 12 KFDLQKRLGKGAYGIVWKAYDKRSRETVALKKIFDAFRNPTDSQRTFREVMFLQEFGKHP 71
Query: 68 NIVRLFDVIHTENK--LTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGV 125
N+++L+++ +N + L FEFM+ DL + KG+ K + +Y QL + +
Sbjct: 72 NVIKLYNIFRADNDRDIYLAFEFMEADLHNVI---KKGSILKDVHK---QYIMCQLFRAI 125
Query: 126 AFCHENRILHRDLKPQNLLINNRGQLKLGDFGLARAF--------GIPVNTFSSEVVTLW 177
F H +LHRDLKP N+L++ ++KL DFGLAR+ G + + V T W
Sbjct: 126 RFLHSGNVLHRDLKPSNVLLDADCRVKLADFGLARSLSSLEDYPEGQKMPDLTEYVATRW 185
Query: 178 YRAPDVLMGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTW 237
YR+P++L+ ++ Y +D+WS GCILAEM++G+ LFPGS+ Q++ I +T+ P
Sbjct: 186 YRSPEILLAAKRYTKGVDMWSLGCILAEMLIGRALFPGSSTINQIERIMNTIAKPSRADI 245
Query: 238 PQVTQLAKYNPL-LPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDAL 296
+ + L P PR L+ ++ +D++ LL P RL+ + L
Sbjct: 246 ASIGSHYAASVLEKMPQRPRKPLDLIITQSQTA----AIDMVQRLLIFAPQKRLTVEQCL 301
Query: 297 NHPWFAEYNH 306
HP+ ++++
Sbjct: 302 VHPYVVQFHN 311
>At3g18040 [T] KOG0660 Mitogen-activated protein kinase
Length = 613
Score = 158 bits (399), Expect = 1e-38
Identities = 113/315 (35%), Positives = 174/315 (54%), Gaps = 31/315 (9%)
Query: 9 TRFKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPSTAI-REISLMKELKHD 67
+R++ E +G G+Y V ++ +G VA+K++ E + +T I REI L++ L+H
Sbjct: 124 SRYQIQEVIGKGSYGVVASAIDTHSGEKVAIKKINDVFEHVSDATRILREIKLLRLLRHP 183
Query: 68 NIVRLFDVIHTENK-----LTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLL 122
+IV + V+ ++ + +VFE M++DL + + ++ L + ++F +QLL
Sbjct: 184 DIVEIKHVMLPPSRREFRDIYVVFELMESDLHQVI------KANDDLTPEHYQFFLYQLL 237
Query: 123 QGVAFCHENRILHRDLKPQNLLINNRGQLKLGDFGLARAF--GIPVNTFSSE-VVTLWYR 179
+G+ F H + HRDLKP+N+L N+ +LK+ DFGLAR P F ++ V T WYR
Sbjct: 238 RGLKFIHTANVFHRDLKPKNILANSDCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYR 297
Query: 180 APDVLMGS--RNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTW 237
AP+ L GS Y +IDIWS GCI AEM+ GKPLFPG N QL ++ D +GTP +
Sbjct: 298 APE-LCGSFFSKYTPAIDIWSIGCIFAEMLTGKPLFPGKNVVHQLDIMTDLLGTPPPEAI 356
Query: 238 PQV--TQLAKY--NPLLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAK 293
++ + +Y N P +P K +D + LLH LL +P R SA+
Sbjct: 357 ARIRNEKARRYLGNMRRKPPVPFTHK-------FPHVDPLALRLLHRLLAFDPKDRPSAE 409
Query: 294 DALNHPWFAEYNHAN 308
+AL P+F Y AN
Sbjct: 410 EALADPYF--YGLAN 422
>CE06762 [T] KOG0660 Mitogen-activated protein kinase
Length = 367
Score = 157 bits (398), Expect = 1e-38
Identities = 95/308 (30%), Positives = 158/308 (50%), Gaps = 27/308 (8%)
Query: 15 EKVGNGTYATVYKGLNKTTGVYVALKEV-KLDSEEGTPSTAIREISLMKELKHDNIVRLF 73
E VG G Y V K ++ VA+K++ + + ++RE+ +++EL H+NI+ +
Sbjct: 61 ENVGAGAYGVVCKAMDTRNKKQVAIKKIPRAFTAHTLAKRSLREVRILRELLHENIIAVL 120
Query: 74 DVIHTENK----LTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGVAFCH 129
D+ E + LV + M+ DL + + +R L +YF +QLL+G+ + H
Sbjct: 121 DMFTAEGAHGKDIYLVMDLMETDLHQILHSRQT------LMEQHFQYFFYQLLRGLKYLH 174
Query: 130 ENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNT---------FSSEVVTLWYRA 180
I+HRDLKP NLL+N L++ DFG+ARA+ + V T WYRA
Sbjct: 175 SAGIIHRDLKPSNLLLNGDCLLRIADFGMARAYASASTVRDDANVGGHMTQYVSTRWYRA 234
Query: 181 PDVLMGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQV 240
P++L Y T +D+WS GCI AEM++ + LFPG + Q+K+I +G+P E+ ++
Sbjct: 235 PEILFSMVEYDTKVDLWSAGCIFAEMLLRRQLFPGKDSVSQIKMIVYYLGSPEEEVINRI 294
Query: 241 TQLAKYNPL--LPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNH 298
T + + P + + E +++ LLQ++P R SA L H
Sbjct: 295 TSDLVRDSIEACGRKTPLPFSAIFPKASPEAR-----NMVSYLLQISPWKRYSADQILQH 349
Query: 299 PWFAEYNH 306
P+ A+Y++
Sbjct: 350 PFMAQYHN 357
>SPBPI064 [G] KOG0658 Glycogen synthase kinase-3
Length = 350
Score = 157 bits (397), Expect = 2e-38
Identities = 91/262 (34%), Positives = 146/262 (54%), Gaps = 19/262 (7%)
Query: 56 REISLMKELKHDNIVRLFDVIHTENK------LTLVFEFMDNDLKKFMDNRNKGNSHKGL 109
RE+ +M+ + H NI++L HT N L L+ E+M + F D R K +
Sbjct: 34 RELQIMRAISHPNIIKLIAFFHTHNPSKDETHLCLLLEYMPETV--FDDMRWYTRRRKSI 91
Query: 110 EMDLVKYFQWQLLQGVAFCHENRILHRDLKPQNLLINNR-GQLKLGDFGLARAFGIPVNT 168
+K + +QL + +A+ H + HRD+KPQNLL++ + G LKL DFG A+ +P
Sbjct: 92 PNLSIKLYAFQLFRALAYLHSTGVCHRDIKPQNLLVDYKTGILKLCDFGSAKVL-VPSEP 150
Query: 169 FSSEVVTLWYRAPDVLMGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDT 228
S + + +YRAP+++ G+ +Y T ID+WS C++AE+ +G+PLFPG + EQL I
Sbjct: 151 NVSYICSRYYRAPELVFGATHYTTKIDVWSAACVIAELFIGRPLFPGDSSVEQLVEIIRV 210
Query: 229 MGTPVEQTWPQVTQLAK--YNPLLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNP 286
+GTP ++ +++ + N LP P L+ ++ +N + N +DLLH +L P
Sbjct: 211 LGTP---SYHEISVMNPNYVNHSLPNVRPHTLESVMPHNCTK----NAMDLLHKMLTYVP 263
Query: 287 DARLSAKDALNHPWFAEYNHAN 308
R+SA + L HP+F E N
Sbjct: 264 SKRISAIEVLTHPFFDELRDPN 285
>7295173 [T] KOG0664 Nemo-like MAPK-related serine/threonine protein kinase
Length = 474
Score = 157 bits (396), Expect = 2e-38
Identities = 96/294 (32%), Positives = 158/294 (53%), Gaps = 15/294 (5%)
Query: 17 VGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPSTAI-REISLMKELKHDNIVRLFDV 75
+G G + V+ + G VALK++ + S + RE+ ++ KH+N++ D+
Sbjct: 46 IGYGAFGVVWAVTDPRDGRRVALKKLPNVFQSLVSSKRVFRELKMLCFFKHENVLSALDI 105
Query: 76 IHTEN-----KLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGVAFCHE 130
+ + ++ ++ E + +DL K + S + L D +K F +Q+L+G+ + H
Sbjct: 106 LQPPHLDFFQEIYVITELLQSDLHKIIV------SPQHLSADHIKVFLYQILRGLKYLHS 159
Query: 131 NRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIP-VNTFSSEVVTLWYRAPDVLMGSRN 189
RILHRD+KP NLL+N+ LK+ DFGLAR + EVVT +YRAP++LMG+R+
Sbjct: 160 ARILHRDIKPGNLLVNSNCVLKICDFGLARVEEPDQAKHMTQEVVTQYYRAPEILMGARH 219
Query: 190 YCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQLAKYNPL 249
Y +++D+WS GCI E++ + LF N +QL+LI + +GTP + + A+ + L
Sbjct: 220 YSSAVDVWSVGCIFGELLGRRILFQAQNPVQQLELITELLGTPTMEDMRHACEGARTHML 279
Query: 250 LPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPWFAE 303
P L ++ V LL +L +PD R+S DAL HP+ E
Sbjct: 280 RRAPKPPSFSVLYTLSSHAT--HEAVHLLCQMLVFDPDKRISVTDALAHPYLDE 331
>Hs7657498 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 419
Score = 156 bits (394), Expect = 4e-38
Identities = 96/296 (32%), Positives = 151/296 (50%), Gaps = 15/296 (5%)
Query: 11 FKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPSTAIREISLMKELK-HDNI 69
+K + K+G GT++ V K + G Y A K++K E +REI ++ L H NI
Sbjct: 4 YKAIGKIGEGTFSEVMKMQSLRDGNYYACKQMKQRFESIEQVNNLREIQALRRLNPHPNI 63
Query: 70 VRLFDVI--HTENKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGVAF 127
+ L +V+ L L+ E MD ++ + + R S K + ++ +QL + +
Sbjct: 64 LMLHEVVFDRKSGSLALICELMDMNIYELIRGRRYPLSEKK-----IMHYMYQLCKSLDH 118
Query: 128 CHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGS 187
H N I HRD+KP+N+LI + LKLGDFG R+ ++ + T WYRAP+ L+
Sbjct: 119 IHRNGIFHRDVKPENILIK-QDVLKLGDFGSCRSV-YSKQPYTEYISTRWYRAPECLLTD 176
Query: 188 RNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQLAKYN 247
Y +D+WS GC+ E+ +PLFPG N+ +Q+ I D +GTP ++ + Q N
Sbjct: 177 GFYTYKMDLWSAGCVFYEIASLQPLFPGVNELDQISKIHDVIGTPAQKILTKFKQSRAMN 236
Query: 248 PLLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPWFAE 303
P + L N L + LLH ++ +PD R++A AL HP+F E
Sbjct: 237 FDFPFKKGSGIPLLTTN-----LSPQCLSLLHAMVAYDPDERIAAHQALQHPYFQE 287
>CE08727 [G] KOG0658 Glycogen synthase kinase-3
Length = 367
Score = 154 bits (388), Expect = 2e-37
Identities = 98/301 (32%), Positives = 168/301 (55%), Gaps = 24/301 (7%)
Query: 8 ETRFKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPSTAIREISLMKELKHD 67
E +F L+ +G G++ VYK + + +A+K++K+D + RE+++M E+ H
Sbjct: 34 EIQFTNLQLIGTGSFGAVYKAVLRENDEPIAIKKIKVDDRFKS-----RELTIMHEMDHP 88
Query: 68 NIVRL--FDVIHTENKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGV 125
NI+RL + V+ EN L V EFM DL +R ++ K + +K + +QLL+G+
Sbjct: 89 NIIRLLYYYVMQQENCLNFVMEFMPKDLAYV--HRQFAHNDKQMPAYSIKLYMFQLLRGI 146
Query: 126 AFCHENRILHRDLKPQNLLIN-NRGQLKLGDFGLARAF--GIPVNTFSSEVVTLWYRAPD 182
F H + I+HRD+KP+NLL++ + G LK+ DFG A+ P T+ + + +YRAP+
Sbjct: 147 GFLHLHNIVHRDIKPKNLLVDESNGILKICDFGSAKRLEKNEPNITY---ICSRYYRAPE 203
Query: 183 VLMGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQ 242
++ GS+NY TSID WS G ++ E++ P+F + + L L GTP ++
Sbjct: 204 LIFGSKNYDTSIDTWSVGTVVGELLHNSPIFLADSAVDILALQIKAFGTPSKE------D 257
Query: 243 LAKYNPLLPPHMPRD--LKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPW 300
+AK+N H+P D +Q L + ++LL+ L++++P R+ +AL P+
Sbjct: 258 MAKWN-YEYVHIPYDTITGVGIQKFIGRKLSLSTLELLNSLMKMDPKLRIKPYEALTLPY 316
Query: 301 F 301
F
Sbjct: 317 F 317
>At1g53510 [T] KOG0660 Mitogen-activated protein kinase
Length = 603
Score = 154 bits (388), Expect = 2e-37
Identities = 107/305 (35%), Positives = 165/305 (54%), Gaps = 25/305 (8%)
Query: 10 RFKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPSTAI-REISLMKELKHDN 68
R++ LE +G G+Y V ++ TG VA+K++ E + + I RE+ L++ L+H +
Sbjct: 12 RYRILEVIGKGSYGVVCAAIDTHTGEKVAIKKINDVFEHISDALRILREVKLLRLLRHPD 71
Query: 69 IVRLFDVIHTENK-----LTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQ 123
IV + ++ +K + +VFE M++DL + + ++ L + ++F +Q+L+
Sbjct: 72 IVEIKSIMLPPSKREFKDIYVVFELMESDLHQVI------KANDDLTREHHQFFLYQMLR 125
Query: 124 GVAFCHENRILHRDLKPQNLLINNRGQLKLGDFGLAR-AFG-IPVNTFSSE-VVTLWYRA 180
+ F H + HRDLKP+N+L N +LK+ DFGLAR AF P F ++ V T WYRA
Sbjct: 126 ALKFMHTANVYHRDLKPKNILANANCKLKVCDFGLARVAFNDTPTTVFWTDYVATRWYRA 185
Query: 181 PDVLMGS--RNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWP 238
P+ L GS Y +ID+WS GCI AE++ GKPLFPG + QL+LI D +GTP +T
Sbjct: 186 PE-LCGSFFSKYTPAIDVWSIGCIFAEVLTGKPLFPGKSVVHQLELITDLLGTPKSETIS 244
Query: 239 QV--TQLAKYNPLLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDAL 296
V + KY + P Q D + LL LL +P R + +AL
Sbjct: 245 GVRNDKARKYLTEMRKKNPVTFSQKFSK-----ADPLALRLLQRLLAFDPKDRPTPAEAL 299
Query: 297 NHPWF 301
P+F
Sbjct: 300 ADPYF 304
>At4g19110 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 256
Score = 153 bits (387), Expect = 3e-37
Identities = 88/251 (35%), Positives = 151/251 (60%), Gaps = 19/251 (7%)
Query: 55 IREISLMKELKHDNIVRLFDVIHTENKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLV 114
+RE+ ++ + H NIV+L +VI + L VFE+M+ +L + M +R K + E D +
Sbjct: 14 LREVKSLRRMNHPNIVKLKEVIRENDILYFVFEYMECNLYQLMKDRQKLFA----EAD-I 68
Query: 115 KYFQWQLLQGVAFCHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNT---FSS 171
K + +Q+ QG+++ H+ HRDLKP+NLL++ + +K+ DFGLAR VN+ F+
Sbjct: 69 KNWCFQVFQGLSYMHQRGYFHRDLKPENLLVS-KDIIKIADFGLARE----VNSSPPFTE 123
Query: 172 EVVTLWYRAPDVLMGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGT 231
V T WYRAP+VL+ S Y + +D+W+ G I+AE++ +P+FPG+++ +++ I +GT
Sbjct: 124 YVSTRWYRAPEVLLQSYVYTSKVDMWAMGAIMAELLSLRPIFPGASEADEIYKICSVIGT 183
Query: 232 PVEQTWPQVTQLAKYNPLLPPHMPR-DLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARL 290
P E+TW + LA P +P L L+ + +E+ ++L+ L +P +R
Sbjct: 184 PTEETWLEGLNLANTINYQFPQLPGVPLSSLMPSASED-----AINLIERLCSWDPSSRP 238
Query: 291 SAKDALNHPWF 301
+A + L HP+F
Sbjct: 239 TAAEVLQHPFF 249
>At3g14720 [T] KOG0660 Mitogen-activated protein kinase
Length = 586
Score = 153 bits (387), Expect = 3e-37
Identities = 106/303 (34%), Positives = 163/303 (52%), Gaps = 21/303 (6%)
Query: 10 RFKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPSTAI-REISLMKELKHDN 68
R++ LE +G G+Y V ++ TG VA+K++ E + + I RE+ L++ L+H +
Sbjct: 12 RYRILEVIGKGSYGVVCAAIDTQTGEKVAIKKINDVFEHVSDALRILREVKLLRLLRHPD 71
Query: 69 IVRLFDVIHTENK-----LTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQ 123
IV + ++ +K + +VFE M++DL + + ++ L + ++F +Q+L+
Sbjct: 72 IVEIKSIMLPPSKREFKDIYVVFELMESDLHQVI------KANDDLTREHHQFFLYQMLR 125
Query: 124 GVAFCHENRILHRDLKPQNLLINNRGQLKLGDFGLARAF--GIPVNTFSSE-VVTLWYRA 180
+ + H + HRDLKP+N+L N +LK+ DFGLAR P F ++ V T WYRA
Sbjct: 126 ALKYMHTANVYHRDLKPKNILANANCKLKVCDFGLARVSFNDTPTTVFWTDYVATRWYRA 185
Query: 181 PDVLMGS--RNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWP 238
P+ L GS Y +IDIWS GCI AE++ GKPLFPG + QL LI D +GTP +T
Sbjct: 186 PE-LCGSFCSKYTPAIDIWSIGCIFAEVLTGKPLFPGKSVVHQLDLITDLLGTPKSETIA 244
Query: 239 QVTQLAKYNPLLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNH 298
V K L ++L Q D + LL LL +P R +A +AL
Sbjct: 245 GVRN-EKARKYLNEMRKKNLVPFSQKFPN--ADPLALRLLQRLLAFDPKDRPTAAEALAD 301
Query: 299 PWF 301
P+F
Sbjct: 302 PYF 304
>Hs20986516 [T] KOG0660 Mitogen-activated protein kinase
Length = 307
Score = 151 bits (381), Expect = 1e-36
Identities = 90/271 (33%), Positives = 144/271 (52%), Gaps = 38/271 (14%)
Query: 10 RFKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPST-AIREISLMKELKHDN 68
R++ L VG+G Y +V + TG+ VA+K++ + + RE+ L+K +KH+N
Sbjct: 23 RYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHEN 82
Query: 69 IVRLFDV------IHTENKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLL 122
++ L DV + N + LV M DL + + + H V++ +Q+L
Sbjct: 83 VIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQKLTDDH-------VQFLIYQIL 135
Query: 123 QGVAFCHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPD 182
+G+ + H I+HRDLKP NL +N +LK+ DFGLAR + + V T WYRAP+
Sbjct: 136 RGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTD---DEMTGYVATRWYRAPE 192
Query: 183 VLMGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQT------ 236
+++ +Y ++DIWS GCI+AE++ G+ LFPG++ +QLKLI +GTP +
Sbjct: 193 IMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPGAELLKKISS 252
Query: 237 ------------WPQVTQLAKYNPLLPPHMP 255
W Q+ +L + PL HMP
Sbjct: 253 ESLSTCWRRCLYWTQIRELQRPKPL---HMP 280
>At1g73670 [T] KOG0660 Mitogen-activated protein kinase
Length = 576
Score = 151 bits (381), Expect = 1e-36
Identities = 103/305 (33%), Positives = 166/305 (53%), Gaps = 25/305 (8%)
Query: 10 RFKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPSTAI-REISLMKELKHDN 68
R++ E VG G+Y V ++ TG VA+K++ + + +T I REI L++ L H +
Sbjct: 89 RYQIQEVVGKGSYGVVGSAIDTHTGERVAIKKINDVFDHISDATRILREIKLLRLLLHPD 148
Query: 69 IVRLFDVIHTENK-----LTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQ 123
+V + ++ ++ + +VFE M++DL + + ++ L + ++F +QLL+
Sbjct: 149 VVEIKHIMLPPSRREFRDVYVVFELMESDLHQVI------KANDDLTPEHHQFFLYQLLR 202
Query: 124 GVAFCHENRILHRDLKPQNLLINNRGQLKLGDFGLARAF--GIPVNTFSSE-VVTLWYRA 180
G+ + H + HRDLKP+N+L N +LK+ DFGLAR P F ++ V T WYRA
Sbjct: 203 GLKYVHAANVFHRDLKPKNILANADCKLKICDFGLARVSFNDAPTAIFWTDYVATRWYRA 262
Query: 181 PDVLMGS--RNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWP 238
P+ L GS Y +IDIWS GCI AEM++GKPLFPG N QL ++ D +GTP +
Sbjct: 263 PE-LCGSFFSKYTPAIDIWSVGCIFAEMLLGKPLFPGKNVVHQLDIMTDFLGTPPPEAIS 321
Query: 239 QV--TQLAKYNPLLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDAL 296
++ + +Y + P + D + + LL L+ +P R SA++AL
Sbjct: 322 KIRNDKARRYLGNMRKKQPVPFSKKFPK-----ADPSALRLLERLIAFDPKDRPSAEEAL 376
Query: 297 NHPWF 301
P+F
Sbjct: 377 ADPYF 381
>CE29466 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 390
Score = 150 bits (380), Expect = 2e-36
Identities = 106/317 (33%), Positives = 162/317 (50%), Gaps = 30/317 (9%)
Query: 9 TRFKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSEEG-TPSTAIREISLMKELKHD 67
TR+ L + G TV + T VA+K+++ + A RE L+ +KH
Sbjct: 36 TRYVNLSFLNAGAQGTVVMADDLVTTQRVAIKKMQQPFVMTMSAKRAYREFILLTTIKHP 95
Query: 68 NIVRLFDVIHTENKLT------LVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQL 121
NI+RL + + L+ LV E M ++L + + L+ + +F +Q
Sbjct: 96 NIIRLLNAFTPDTSLSTFREVYLVMELMTHNLHEVIHRLR-------LDHKTLSFFVYQS 148
Query: 122 LQGVAFCHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSE-VVTLWYRA 180
L + H + ++HRDLKP N+++N+R LK+ DFGLAR + + S+ VVT +YRA
Sbjct: 149 LCAIKHLHNSGVIHRDLKPSNIVVNDRCVLKVLDFGLARKKNVDTSMRMSDYVVTRYYRA 208
Query: 181 PDVLMGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQV 240
P+V++G Y +DIWS GCI AEMI LFPG + +Q I+ +GTP + Q+
Sbjct: 209 PEVILGLP-YSEKVDIWSVGCIFAEMINHTVLFPGKDRIDQWTKIYSVLGTPDDHFISQL 267
Query: 241 TQ-LAKYNPLLPPHMPRDLKQLLQN--------NTEEVLDDNVV-DLLHGLLQLNPDARL 290
Q A Y LP H R +++ + N L +V DLL +L++NP+ R
Sbjct: 268 GQSAAMYVRSLPRHQARAFSEIVPDTNFLPETENPRVHLTPHVARDLLFNMLKINPEERY 327
Query: 291 SAKDALNHP----WFAE 303
S +DALNHP WF +
Sbjct: 328 SVEDALNHPYVKLWFKD 344
>Hs21237745 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 424
Score = 150 bits (378), Expect = 3e-36
Identities = 97/306 (31%), Positives = 161/306 (51%), Gaps = 25/306 (8%)
Query: 10 RFKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPST-AIREISLMKELKHDN 68
R++QL+ +G+G V + G+ VA+K++ + T + A RE+ L+K + H N
Sbjct: 25 RYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRPFQNQTHAKRAYRELVLLKCVNHKN 84
Query: 69 IVRLFDVIHTENKLT------LVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLL 122
I+ L +V + L LV E MD +L + + H L+ + + Y +Q+L
Sbjct: 85 IISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVI--------HMELDHERMSYLLYQML 136
Query: 123 QGVAFCHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPD 182
G+ H I+HRDLKP N+++ + LK+ DFGLAR + VVT +YRAP+
Sbjct: 137 CGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLART-ACTNFMMTPYVVTRYYRAPE 195
Query: 183 VLMGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTP----VEQTWP 238
V++G Y ++DIWS GCI+AEM++ K LFPG + +Q + + +GTP +++ P
Sbjct: 196 VILG-MGYKENVDIWSVGCIMAEMVLHKVLFPGRDYIDQWNKVIEQLGTPSAEFMKKLQP 254
Query: 239 QVTQLAKYNPLLP----PHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKD 294
V + P P + D ++ +++ DLL +L ++PD R+S +
Sbjct: 255 TVRNYVENRPKYPGIKFEELFPDWIFPSESERDKIKTSQARDLLSKMLVIDPDKRISVDE 314
Query: 295 ALNHPW 300
AL HP+
Sbjct: 315 ALRHPY 320
>Hs21237742 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 382
Score = 150 bits (378), Expect = 3e-36
Identities = 97/306 (31%), Positives = 161/306 (51%), Gaps = 25/306 (8%)
Query: 10 RFKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPST-AIREISLMKELKHDN 68
R++QL+ +G+G V + G+ VA+K++ + T + A RE+ L+K + H N
Sbjct: 25 RYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRPFQNQTHAKRAYRELVLLKCVNHKN 84
Query: 69 IVRLFDVIHTENKLT------LVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLL 122
I+ L +V + L LV E MD +L + + H L+ + + Y +Q+L
Sbjct: 85 IISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVI--------HMELDHERMSYLLYQML 136
Query: 123 QGVAFCHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPD 182
G+ H I+HRDLKP N+++ + LK+ DFGLAR + VVT +YRAP+
Sbjct: 137 CGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLART-ACTNFMMTPYVVTRYYRAPE 195
Query: 183 VLMGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTP----VEQTWP 238
V++G Y ++DIWS GCI+AEM++ K LFPG + +Q + + +GTP +++ P
Sbjct: 196 VILG-MGYKENVDIWSVGCIMAEMVLHKVLFPGRDYIDQWNKVIEQLGTPSAEFMKKLQP 254
Query: 239 QVTQLAKYNPLLP----PHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKD 294
V + P P + D ++ +++ DLL +L ++PD R+S +
Sbjct: 255 TVRNYVENRPKYPGIKFEELFPDWIFPSESERDKIKTSQARDLLSKMLVIDPDKRISVDE 314
Query: 295 ALNHPW 300
AL HP+
Sbjct: 315 ALRHPY 320
>Hs20502986 [T] KOG0660 Mitogen-activated protein kinase
Length = 277
Score = 150 bits (378), Expect = 3e-36
Identities = 97/257 (37%), Positives = 140/257 (53%), Gaps = 34/257 (13%)
Query: 6 RYETRFKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPST-AIREISLMKEL 64
R R+ ++G G Y V+K +++ TG VA+K++ + T + REI+L++E
Sbjct: 8 RIVRRYLLRRQLGQGAYGIVWKAVDRRTGEVVAIKKIFDAFRDKTDAQRTFREITLLQEF 67
Query: 65 -KHDNIVRLFDVIHTENK--LTLVFEFM-----------------DNDLKKFMDNRNKGN 104
H NI+ L DVI EN + LVFEFM D DL + KG
Sbjct: 68 GDHPNIISLLDVIRAENDRDIYLVFEFMGCPPSPPPPTAVRTLSADTDLNAVI---RKG- 123
Query: 105 SHKGLEMDL-VKYFQWQLLQGVAFCHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFG 163
GL D+ V+ +QLL+ F H ++HRD KP N+L++ +KL DFGLAR+ G
Sbjct: 124 ---GLLQDVHVRSIFYQLLRATRFLHSGHVVHRDQKPSNVLLDANCTVKLCDFGLARSLG 180
Query: 164 -IPVN----TFSSEVVTLWYRAPDVLMGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSND 218
+P + V T WYRAP+VL+ S Y +D+WS GCIL EM+ G+PLFPG++
Sbjct: 181 DLPEGPEDQAVTEYVATRWYRAPEVLLSSHRYTLGVDMWSLGCILGEMLRGRPLFPGTST 240
Query: 219 EEQLKLIFDTMGTPVEQ 235
QL+LI +T+ P E+
Sbjct: 241 LHQLELILETIPPPSEE 257
>At5g19010 [T] KOG0660 Mitogen-activated protein kinase
Length = 567
Score = 149 bits (377), Expect = 4e-36
Identities = 106/304 (34%), Positives = 165/304 (53%), Gaps = 21/304 (6%)
Query: 9 TRFKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPSTAI-REISLMKELKHD 67
+R++ E +G G+Y V + TG VA+K++ E + +T I REI L++ L+H
Sbjct: 23 SRYRIEEVIGKGSYGVVCSAYDTHTGEKVAIKKINDIFEHVSDATRILREIKLLRLLRHP 82
Query: 68 NIVRLFDVIHTENK-----LTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLL 122
+IV + ++ ++ + +VFE M++DL + + ++ L + ++F +QLL
Sbjct: 83 DIVEIKHILLPPSRREFRDIYVVFELMESDLHQVI------KANDDLTPEHYQFFLYQLL 136
Query: 123 QGVAFCHENRILHRDLKPQNLLINNRGQLKLGDFGLAR-AFG-IPVNTFSSE-VVTLWYR 179
+G+ + H + HRDLKP+N+L N +LK+ DFGLAR AF P F ++ V T WYR
Sbjct: 137 RGLKYIHTANVFHRDLKPKNILANADCKLKICDFGLARVAFNDTPTAIFWTDYVATRWYR 196
Query: 180 APDVLMGS--RNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTW 237
AP+ L GS Y +IDIWS GCI AE++ GKPLFPG N QL L+ D +GTP +
Sbjct: 197 APE-LCGSFFSKYTPAIDIWSIGCIFAELLTGKPLFPGKNVVHQLDLMTDMLGTPSAEAI 255
Query: 238 PQVTQLAKYNPLLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALN 297
+V L R K + ++ D + LL +L P R +A++AL
Sbjct: 256 GRVRNEKARRYL---SSMRKKKPIPFSHKFPHTDPLALRLLEKMLSFEPKDRPTAEEALA 312
Query: 298 HPWF 301
+F
Sbjct: 313 DVYF 316
>At1g57870 [G] KOG0658 Glycogen synthase kinase-3
Length = 420
Score = 149 bits (376), Expect = 5e-36
Identities = 102/303 (33%), Positives = 164/303 (53%), Gaps = 28/303 (9%)
Query: 17 VGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPSTAIREISLMKELKHDNIVRLFDVI 76
VG G++ V++ + TG VA+K+V D RE+ +M+ L H N+V L
Sbjct: 88 VGTGSFGMVFQAKCRETGEVVAIKKVLQDKRYKN-----RELQIMQMLDHPNVVCLKHSF 142
Query: 77 H--TENK---LTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGVAFCHEN 131
+ TEN+ L LV EF+ + + R+ ++ + + VK + +Q+ +G+A+ H
Sbjct: 143 YSRTENEEVYLNLVLEFVPETVNRTA--RSYSRMNQLMPLIYVKLYTYQICRGLAYLHNC 200
Query: 132 -RILHRDLKPQNLLIN-NRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGSRN 189
+ HRD+KPQNLL+N + QLK+ DFG A+ + S + + +YRAP+++ G+
Sbjct: 201 CGLCHRDIKPQNLLVNPHTHQLKICDFGSAKVL-VKGEPNISYICSRYYRAPELIFGATE 259
Query: 190 YCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTW----PQVTQLAK 245
Y T+IDIWS GC++AE+++G+PLFPG + +QL I +GTP + P T+ K
Sbjct: 260 YTTAIDIWSTGCVMAELLLGQPLFPGESGVDQLVEIIKVLGTPTREEIKCMNPNYTEF-K 318
Query: 246 YNPLLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPWFAEYN 305
+ P + PH + Q + L VDLL Q +P+ R +A +A HP+F E
Sbjct: 319 F-PQIKPHPWHKVFQ-------KRLPPEAVDLLCRFFQYSPNLRCTAVEACIHPFFDELR 370
Query: 306 HAN 308
N
Sbjct: 371 DPN 373
>Hs20986514 [T] KOG0660 Mitogen-activated protein kinase
Length = 297
Score = 149 bits (375), Expect = 7e-36
Identities = 82/230 (35%), Positives = 132/230 (56%), Gaps = 17/230 (7%)
Query: 10 RFKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPST-AIREISLMKELKHDN 68
R++ L VG+G Y +V + TG+ VA+K++ + + RE+ L+K +KH+N
Sbjct: 23 RYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHEN 82
Query: 69 IVRLFDV------IHTENKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLL 122
++ L DV + N + LV M DL + + + H V++ +Q+L
Sbjct: 83 VIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQKLTDDH-------VQFLIYQIL 135
Query: 123 QGVAFCHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPD 182
+G+ + H I+HRDLKP NL +N +LK+ DFGLAR + + V T WYRAP+
Sbjct: 136 RGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTD---DEMTGYVATRWYRAPE 192
Query: 183 VLMGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTP 232
+++ +Y ++DIWS GCI+AE++ G+ LFPG++ +QLKLI +GTP
Sbjct: 193 IMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTP 242
>7290342 [G] KOG0658 Glycogen synthase kinase-3
Length = 1008
Score = 149 bits (375), Expect = 7e-36
Identities = 92/307 (29%), Positives = 163/307 (52%), Gaps = 28/307 (9%)
Query: 8 ETRFKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPSTAIREISLMKELKHD 67
E + + +GNG++ V++ TG VA+K+V D RE+ +M++L+H
Sbjct: 545 EVSYTDTKVIGNGSFGVVFQAKLCDTGELVAIKKVLQDRRFKN-----RELQIMRKLEHC 599
Query: 68 NIVRLFDVIHTENK------LTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQL 121
NIV+L ++ + L LV E++ + K R + + + ++ ++ + +QL
Sbjct: 600 NIVKLLYFFYSSGEKRDEVFLNLVLEYIPETVYKVA--RQYAKTKQTIPINFIRLYMYQL 657
Query: 122 LQGVAFCHENRILHRDLKPQNLLIN-NRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRA 180
+ +A+ H I HRD+KPQNLL++ LKL DFG A+ + S + + +YRA
Sbjct: 658 FRSLAYIHSLGICHRDIKPQNLLLDPETAVLKLCDFGSAKQL-LHGEPNVSYICSRYYRA 716
Query: 181 PDVLMGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQV 240
P+++ G+ NY T ID+WS GC+LAE+++G+P+FPG + +QL + +GTP +
Sbjct: 717 PELIFGAINYTTKIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEVIKVLGTPTRE----- 771
Query: 241 TQLAKYNPLLPPHMPRDLKQLLQNNTEEVL----DDNVVDLLHGLLQLNPDARLSAKDAL 296
Q+ + N P + Q+ + ++V ++L+ LL+ P AR++ A
Sbjct: 772 -QIREMN---PNYTEFKFPQIKSHPWQKVFRIRTPTEAINLVSLLLEYTPSARITPLKAC 827
Query: 297 NHPWFAE 303
HP+F E
Sbjct: 828 AHPFFDE 834
>SPAC1687.15 [G] KOG0658 Glycogen synthase kinase-3
Length = 387
Score = 147 bits (372), Expect = 1e-35
Identities = 102/300 (34%), Positives = 156/300 (52%), Gaps = 22/300 (7%)
Query: 17 VGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPSTAIREISLMKELKHDNIVRLFDVI 76
VG+G++ V + + A+K V D RE+ +M+ +KH NIV L
Sbjct: 38 VGSGSFGVVMQVHLIESDSKAAIKRVLQDKRFKN-----RELQIMRIMKHPNIVDLIAYY 92
Query: 77 HT------ENKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGVAFCHE 130
+T E L LV EFM + + +R + M VK + +QLL+ +A+ H
Sbjct: 93 YTTGDNSDEVYLNLVLEFMPETI--YRASRLYTRQKLSMPMLEVKLYIYQLLRSLAYIHA 150
Query: 131 NRILHRDLKPQNLLIN-NRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGSRN 189
+ I HRD+KPQNLL++ G LKL DFG A+ + S + + +YRAP+++ G+ +
Sbjct: 151 SGICHRDIKPQNLLLDPENGILKLCDFGSAKIL-VAGEPNVSYICSRYYRAPELIFGATD 209
Query: 190 YCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQLAKYNPL 249
Y +IDIWS GC++AE+++G PLFPG + +QL I +GTP + Q+ NP
Sbjct: 210 YTHAIDIWSTGCVMAELMLGHPLFPGESGIDQLVEIIKILGTPSRE------QIKTMNPN 263
Query: 250 LPPH-MPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPWFAEYNHAN 308
H P+ Q L + + +DLL +LQ P RL+A +A+ HP+F E N
Sbjct: 264 YMEHRFPQIRPQPLSRVFSRSVPLDALDLLSKMLQYTPTDRLTAAEAMCHPFFDELRDPN 323
>SPBC119.08 [T] KOG0660 Mitogen-activated protein kinase
Length = 422
Score = 146 bits (369), Expect = 3e-35
Identities = 106/314 (33%), Positives = 162/314 (50%), Gaps = 29/314 (9%)
Query: 8 ETRFKQLEKVGNGTYATVYKGLNKTTGVY--VALKEV-KLDSEEGTPSTAIREISLMKEL 64
E FK ++++G G Y V N + VA+K++ + S+ A+REI L+
Sbjct: 18 EPNFKVVKELGQGAYGIVCAARNVASKDQEAVAIKKITNVFSKSILTKRALREIKLLIHF 77
Query: 65 K-HDNIVRLFDVI----HTENKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQW 119
+ H NI ++D+ + N++ + E M+ DL + S + L + F +
Sbjct: 78 RNHRNITCIYDLDIINPYNFNEVYIYEELMEADLNAII------KSGQPLTDAHFQSFIY 131
Query: 120 QLLQGVAFCHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNT-----FSSE-V 173
Q+L G+ + H ++HRDLKP NLL+N +LK+ DFGLAR G N F +E V
Sbjct: 132 QILCGLKYIHSANVIHRDLKPGNLLVNADCELKICDFGLAR--GCSENPEENPGFMTEYV 189
Query: 174 VTLWYRAPDVLMGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPV 233
T WYRAP++++ +Y ID+WS GCILAE++ G PLF G + QL LI +GTP
Sbjct: 190 ATRWYRAPEIMLSFSSYHKGIDVWSVGCILAELLGGTPLFKGKDFVHQLNLILHQLGTPD 249
Query: 234 EQTWPQV--TQLAKYNPLLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLS 291
E+T + ++ +Y LP P + L DLL LL +P+ R+S
Sbjct: 250 EETLSHISSSRAQEYVRSLPKQRPIPFETNFPKANPLAL-----DLLAKLLAFDPNRRIS 304
Query: 292 AKDALNHPWFAEYN 305
DAL HP+ A ++
Sbjct: 305 VDDALEHPYLAVWH 318
>At3g05840 [G] KOG0658 Glycogen synthase kinase-3
Length = 409
Score = 146 bits (369), Expect = 3e-35
Identities = 95/300 (31%), Positives = 158/300 (52%), Gaps = 22/300 (7%)
Query: 17 VGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPSTAIREISLMKELKHDNIVRLFDVI 76
VG+G++ V++ TG VA+K+V D RE+ M+ L H N+V L
Sbjct: 79 VGHGSFGVVFQAKCLETGETVAIKKVLQDRRYKN-----RELQTMRLLDHPNVVSLKHCF 133
Query: 77 HTENK-----LTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGVAFCHEN 131
+ + L LV E++ + + + + NK N + + VK + +Q+ + +++ H
Sbjct: 134 FSTTEKDELYLNLVLEYVPETVHRVIKHYNKLNQR--MPLVYVKLYTYQIFRSLSYIHRC 191
Query: 132 -RILHRDLKPQNLLIN-NRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGSRN 189
+ HRD+KPQNLL+N + Q+KL DFG A+ + S + + +YRAP+++ G+
Sbjct: 192 IGVCHRDIKPQNLLVNPHTHQVKLCDFGSAKVL-VKGEPNISYICSRYYRAPELIFGATE 250
Query: 190 YCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQLAKYNPL 249
Y T+ID+WS GC+LAE+++G+PLFPG + +QL I +GTP + ++ NP
Sbjct: 251 YTTAIDVWSAGCVLAELLLGQPLFPGESGVDQLVEIIKVLGTPTRE------EIKCMNPN 304
Query: 250 LPP-HMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPWFAEYNHAN 308
P+ + + VDL+ LLQ +P+ R +A D+L HP+F E N
Sbjct: 305 YTEFKFPQIKAHPWHKIFHKRMPPEAVDLVSRLLQYSPNLRCAALDSLVHPFFDELRDPN 364
>CE21401 [G] KOG0658 Glycogen synthase kinase-3
Length = 362
Score = 146 bits (368), Expect = 4e-35
Identities = 93/304 (30%), Positives = 157/304 (51%), Gaps = 22/304 (7%)
Query: 8 ETRFKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPSTAIREISLMKELKHD 67
E + + +GNG++ V+ TT VA+K+V D RE+ +M++L H
Sbjct: 33 EISYYDQKVIGNGSFGVVFLAKLSTTNEMVAIKKVLQDKRFKN-----RELQIMRKLNHP 87
Query: 68 NIVRLFDVIHTENK------LTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQL 121
NIV+L ++ + L L+ E++ + + R+ + + M VK + +QL
Sbjct: 88 NIVKLKYFFYSSGEKKDELYLNLILEYVPETVYRVA--RHYSKQRQQIPMIYVKLYMYQL 145
Query: 122 LQGVAFCHENRILHRDLKPQNLLIN-NRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRA 180
L+ +A+ H I HRD+KPQNLLI+ G LKL DFG A+ + + S + + +YRA
Sbjct: 146 LRSLAYIHSIGICHRDIKPQNLLIDPESGVLKLCDFGSAK-YLVRNEPNVSYICSRYYRA 204
Query: 181 PDVLMGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQV 240
P+++ G+ NY SID+WS G ++AE+++G+P+FPG + +QL I +GTP +
Sbjct: 205 PELIFGATNYTNSIDVWSAGTVMAELLLGQPIFPGDSGVDQLVEIIKVLGTPTRE----- 259
Query: 241 TQLAKYNPLLPPHMPRDLKQLLQNNTEEV-LDDNVVDLLHGLLQLNPDARLSAKDALNHP 299
Q+ NP +K N V +DL+ +++ P +R + + A H
Sbjct: 260 -QIQSMNPNYKEFKFPQIKAHPWNKVFRVHTPAEAIDLISKIIEYTPTSRPTPQAACQHA 318
Query: 300 WFAE 303
+F E
Sbjct: 319 FFDE 322
>At5g26751 [G] KOG0658 Glycogen synthase kinase-3
Length = 413
Score = 145 bits (367), Expect = 6e-35
Identities = 95/300 (31%), Positives = 157/300 (51%), Gaps = 22/300 (7%)
Query: 17 VGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPSTAIREISLMKELKHDNIVRLFDVI 76
VG+G++ V++ TG VA+K+V D RE+ M+ L H N+V L
Sbjct: 75 VGHGSFGVVFQAKCLETGETVAIKKVLQDRRYKN-----RELQTMRLLDHPNVVSLKHCF 129
Query: 77 HTENK-----LTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGVAFCHEN 131
+ + L LV E++ + + + + NK N + + VK + +Q+ + +++ H
Sbjct: 130 FSTTEKDELYLNLVLEYVPETVHRVIKHYNKLNQR--MPLIYVKLYTYQIFRALSYIHRC 187
Query: 132 -RILHRDLKPQNLLIN-NRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGSRN 189
+ HRD+KPQNLL+N + Q+KL DFG A+ + S + + +YRAP+++ G+
Sbjct: 188 IGVCHRDIKPQNLLVNPHTHQVKLCDFGSAKVL-VKGEPNISYICSRYYRAPELIFGATE 246
Query: 190 YCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQLAKYNPL 249
Y T+ID+WS GC+LAE+++G+PLFPG + +QL I +GTP + ++ NP
Sbjct: 247 YTTAIDVWSAGCVLAELLLGQPLFPGESGVDQLVEIIKVLGTPTRE------EIKCMNPN 300
Query: 250 LPP-HMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPWFAEYNHAN 308
P+ + + VDL+ LLQ +P+ R +A D L HP+F E N
Sbjct: 301 YTEFKFPQIKAHPWHKIFHKRMPPEAVDLVSRLLQYSPNLRSAALDTLVHPFFDELRDPN 360
>At2g01450 [T] KOG0660 Mitogen-activated protein kinase
Length = 516
Score = 145 bits (367), Expect = 6e-35
Identities = 109/307 (35%), Positives = 163/307 (52%), Gaps = 27/307 (8%)
Query: 9 TRFKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPSTAI-REISLMKELKHD 67
++++ E VG G+Y V TG VA+K++ E + + I REI L++ L+H
Sbjct: 14 SQYQIQEVVGKGSYGVVASAECPHTGGKVAIKKMTNVFEHVSDAIRILREIKLLRLLRHP 73
Query: 68 NIVRLFDVI----HTENK-LTLVFEFMDNDLKKFMD-NRNKGNSHKGLEMDLVKYFQWQL 121
+IV + ++ E K + +VFE M++DL + N + H ++F +QL
Sbjct: 74 DIVEIKHIMLPPCRKEFKDIYVVFELMESDLHHVLKVNDDLTPQHH-------QFFLYQL 126
Query: 122 LQGVAFCHENRILHRDLKPQNLLINNRGQLKLGDFGLARAF--GIPVNTFSSE-VVTLWY 178
L+G+ F H + HRDLKP+N+L N ++K+ D GLAR P F ++ V T WY
Sbjct: 127 LRGLKFMHSAHVFHRDLKPKNILANADCKIKICDLGLARVSFTDSPSAVFWTDYVATRWY 186
Query: 179 RAPDVLMGS--RNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQT 236
RAP+ L GS NY +ID+WS GCI AEM+ GKPLFPG N QL+L+ D +GTP T
Sbjct: 187 RAPE-LCGSFYSNYTPAIDMWSVGCIFAEMLTGKPLFPGKNVVHQLELVTDLLGTPSPIT 245
Query: 237 WPQV--TQLAKYNPLLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKD 294
++ + KY + P N +D + LL L+ +P R SA++
Sbjct: 246 LSRIRNEKARKYLGNMRRKDPVPFTHKFPN-----IDPVALKLLQRLIAFDPKDRPSAEE 300
Query: 295 ALNHPWF 301
AL P+F
Sbjct: 301 ALADPYF 307
>At1g09840 [G] KOG0658 Glycogen synthase kinase-3
Length = 421
Score = 145 bits (367), Expect = 6e-35
Identities = 100/303 (33%), Positives = 162/303 (53%), Gaps = 28/303 (9%)
Query: 17 VGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPSTAIREISLMKELKHDNIVRLFDVI 76
VG G++ V++ + TG VA+K+V D RE+ +M+ L H N V L
Sbjct: 89 VGTGSFGMVFQAKCRETGEVVAIKKVLQDKRYKN-----RELQIMQMLDHPNAVALKHSF 143
Query: 77 --HTENK---LTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGVAFCHEN 131
T+N+ L LV EF+ + + R+ +++ + + VK + +Q+ + +A+ H +
Sbjct: 144 FSRTDNEEVYLNLVLEFVPETVNRVA--RSYSRTNQLMPLIYVKLYTYQICRALAYIHNS 201
Query: 132 -RILHRDLKPQNLLIN-NRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGSRN 189
+ HRD+KPQNLL+N + QLK+ DFG A+ + S + + +YRAP+++ G+
Sbjct: 202 FGLCHRDIKPQNLLVNPHTHQLKICDFGSAKVL-VKGEPNVSYICSRYYRAPELIFGASE 260
Query: 190 YCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTW----PQVTQLAK 245
Y T+IDIWS GC++AE+++G+PLFPG + +QL I +GTP + P T+ K
Sbjct: 261 YTTAIDIWSTGCVMAELLLGQPLFPGESGVDQLVEIIKVLGTPTREEIKCMNPNYTEF-K 319
Query: 246 YNPLLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPWFAEYN 305
+ P + PH + Q + L VDLL Q +P+ R +A +A HP F E
Sbjct: 320 F-PQIKPHPWHKVFQ-------KRLPPEAVDLLCRFFQYSPNLRCTALEACIHPLFDELR 371
Query: 306 HAN 308
N
Sbjct: 372 DPN 374
>YMR139w [G] KOG0658 Glycogen synthase kinase-3
Length = 370
Score = 145 bits (366), Expect = 7e-35
Identities = 94/300 (31%), Positives = 155/300 (51%), Gaps = 21/300 (7%)
Query: 11 FKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPSTAIREISLMKELKHDNIV 70
F E VG+G++ V+ + + T VA+K+V D RE+ +MK L H NI+
Sbjct: 39 FPTTEVVGHGSFGVVFATVIQETNEKVAIKKVLQDKRFKN-----RELEIMKMLSHINII 93
Query: 71 RLFDVIHTENK-----LTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGV 125
L + + L L+ E+M L + + R+ + + +KY+ +QL + +
Sbjct: 94 DLKYFFYERDSQDEIYLNLILEYMPQSLYQRL--RHFVHQRTPMSRLEIKYYMFQLFKSL 151
Query: 126 AFCHE-NRILHRDLKPQNLLIN-NRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDV 183
+ H + HRD+KPQNLL++ LKL DFG A+ P S + + +YRAP++
Sbjct: 152 NYLHHFANVCHRDIKPQNLLVDPETWSLKLCDFGSAKQLK-PTEPNVSYICSRYYRAPEL 210
Query: 184 LMGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQL 243
+ G+ NY IDIWS GC++AE+++G+P+FPG + +QL I +GTP +Q ++
Sbjct: 211 IFGATNYTNQIDIWSSGCVMAELLLGQPMFPGESGIDQLVEIIKILGTPSKQ------EI 264
Query: 244 AKYNPLLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPWFAE 303
NP H +K + + + DD V+ L +L+ +P R +A L P+F E
Sbjct: 265 CSMNPNYMEHKFPQIKPIPLSRVFKKEDDQTVEFLADVLKYDPLERFNALQCLCSPYFDE 324
>Hs20986499 [T] KOG0660 Mitogen-activated protein kinase
Length = 677
Score = 145 bits (366), Expect = 7e-35
Identities = 83/223 (37%), Positives = 125/223 (55%), Gaps = 17/223 (7%)
Query: 89 MDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGVAFCHENRILHRDLKPQNLLINNR 148
M++DL + + +S + L ++ V+YF +QLL+G+ + H +++HRDLKP NLL+N
Sbjct: 1 MESDLHQII------HSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNEN 54
Query: 149 GQLKLGDFGLARAFGIPV---NTFSSE-VVTLWYRAPDVLMGSRNYCTSIDIWSCGCILA 204
+LK+GDFG+AR F +E V T WYRAP++++ Y +ID+WS GCI
Sbjct: 55 CELKIGDFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFG 114
Query: 205 EMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQV--TQLAKYNPLLPPHMPRDLKQLL 262
EM+ + LFPG N QL+LI +GTP V ++ Y LPP P + +
Sbjct: 115 EMLARRQLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVY 174
Query: 263 QNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPWFAEYN 305
D + LL +L+ P AR+SA AL HP+ A+Y+
Sbjct: 175 PG-----ADRQALSLLGRMLRFEPSARISAAAALRHPFLAKYH 212
>At1g06390 [G] KOG0658 Glycogen synthase kinase-3
Length = 407
Score = 145 bits (366), Expect = 7e-35
Identities = 95/300 (31%), Positives = 155/300 (51%), Gaps = 22/300 (7%)
Query: 17 VGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPSTAIREISLMKELKHDNIVRLFDVI 76
VG G++ V++ TG VA+K+V D RE+ LM+ + H N++ L
Sbjct: 76 VGTGSFGIVFQAKCLETGESVAIKKVLQDRRYKN-----RELQLMRPMDHPNVISLKHCF 130
Query: 77 HTENK-----LTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGVAFCHE- 130
+ L LV E++ L + + R+ +S++ + + VK + +Q+ +G+A+ H
Sbjct: 131 FSTTSRDELFLNLVMEYVPETLYRVL--RHYTSSNQRMPIFYVKLYTYQIFRGLAYIHTV 188
Query: 131 NRILHRDLKPQNLLINN-RGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGSRN 189
+ HRD+KPQNLL++ Q+KL DFG A+ + S + + +YRAP+++ G+
Sbjct: 189 PGVCHRDVKPQNLLVDPLTHQVKLCDFGSAKVL-VKGEPNISYICSRYYRAPELIFGATE 247
Query: 190 YCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQLAKYNPL 249
Y SIDIWS GC+LAE+++G+PLFPG N +QL I +GTP + ++ NP
Sbjct: 248 YTASIDIWSAGCVLAELLLGQPLFPGENSVDQLVEIIKVLGTPTRE------EIRCMNPN 301
Query: 250 LPP-HMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPWFAEYNHAN 308
P+ + + +DL LLQ +P R +A +A HP+F E N
Sbjct: 302 YTDFRFPQIKAHPWHKVFHKRMPPEAIDLASRLLQYSPSLRCTALEACAHPFFNELREPN 361
>YHR030c [T] KOG0660 Mitogen-activated protein kinase
Length = 484
Score = 145 bits (365), Expect = 9e-35
Identities = 98/309 (31%), Positives = 163/309 (52%), Gaps = 23/309 (7%)
Query: 8 ETRFKQLEKVGNGTYATVYKG--LNKTTGVYVALKEV-KLDSEEGTPSTAIREISLMKEL 64
+ RF+ ++++G+G Y V VA+K+V + S+ ++RE+ L++
Sbjct: 20 DKRFQLIKEIGHGAYGIVCSARFAEAAEDTTVAIKKVTNVFSKTLLCKRSLRELKLLRHF 79
Query: 65 K-HDNIVRLFD---VIHTE---NKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYF 117
+ H NI L+D V + + N L L E M+ D+ + + S + L + F
Sbjct: 80 RGHKNITCLYDMDIVFYPDGSINGLYLYEELMECDMHQII------KSGQPLTDAHYQSF 133
Query: 118 QWQLLQGVAFCHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFG---IPVNTFSSE-V 173
+Q+L G+ + H +LHRDLKP NLL+N QLK+ DFGLAR + + + F +E V
Sbjct: 134 TYQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENSQFLTEYV 193
Query: 174 VTLWYRAPDVLMGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPV 233
T WYRAP++++ + Y +ID+WS GCILAE + GKP+F G + QL I +GTP
Sbjct: 194 ATRWYRAPEIMLSYQGYTKAIDVWSAGCILAEFLGGKPIFKGKDYVNQLNQILQVLGTPP 253
Query: 234 EQTWPQVTQLAKYNPLLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAK 293
++T + ++ N H + ++ N + +DLL +L +P R++
Sbjct: 254 DET---LRRIGSKNVQDYIHQLGFIPKVPFVNLYPNANSQALDLLEQMLAFDPQKRITVD 310
Query: 294 DALNHPWFA 302
+AL HP+ +
Sbjct: 311 EALEHPYLS 319
>CE17305 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 375
Score = 145 bits (365), Expect = 9e-35
Identities = 103/309 (33%), Positives = 158/309 (50%), Gaps = 26/309 (8%)
Query: 9 TRFKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSE-EGTPSTAIREISLMKELKHD 67
TR+ L+ + G V + T VA+K+++ + A RE L+ LKH
Sbjct: 27 TRYVNLKFLNVGAQGIVVMADDLVTTQRVAIKKMQQPFLLTMSARRAYREFILLTTLKHP 86
Query: 68 NIVRLFDVIHTENKLT------LVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQL 121
NI+RL + + L+ LV EFM ++L + + L+ + + + +Q
Sbjct: 87 NIIRLLNAFTPDTSLSSFQEVYLVMEFMTHNLHEVIHRLR-------LDHETLSFLVYQS 139
Query: 122 LQGVAFCHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAP 181
L + H +HRDLKP N+++N R LK+ DFGLAR + + S V T +YRAP
Sbjct: 140 LCAIKHLHNLGFIHRDLKPSNIVVNERCVLKVLDFGLARRRNVDMR-MSDYVGTRYYRAP 198
Query: 182 DVLMGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVT 241
+V++G NY +DIWS GCILAEMI LFPG + +Q I + TP + Q+
Sbjct: 199 EVILGL-NYSEKVDIWSVGCILAEMINHTVLFPGKDIRDQWTQISSVLRTPDDHFINQLE 257
Query: 242 QL-AKYNPLLPPHMPRDLKQLLQNN-----TEEVLDDNVV----DLLHGLLQLNPDARLS 291
+ A Y LP H+ R +++ ++ TE D + DLL +L++NP+ R S
Sbjct: 258 PIGAVYVRSLPQHLARAFNEIVPDSNFLPETENPKDHLTLHMARDLLFNMLKINPEERYS 317
Query: 292 AKDALNHPW 300
+DALNHP+
Sbjct: 318 VEDALNHPY 326
>At4g18710 [G] KOG0658 Glycogen synthase kinase-3
Length = 380
Score = 145 bits (365), Expect = 9e-35
Identities = 95/300 (31%), Positives = 152/300 (50%), Gaps = 22/300 (7%)
Query: 17 VGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPSTAIREISLMKELKHDNIVRLFDVI 76
VG G++ V++ TG VA+K+V D RE+ LM+ + H N+V L
Sbjct: 46 VGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKN-----RELQLMRVMDHPNVVCLKHCF 100
Query: 77 HTENK-----LTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGVAFCHEN 131
+ L LV E++ L + + + + N + + VK + +Q+ +G+A+ H
Sbjct: 101 FSTTSKDELFLNLVMEYVPESLYRVLKHYSSANQR--MPLVYVKLYMYQIFRGLAYIHNV 158
Query: 132 R-ILHRDLKPQNLLINN-RGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGSRN 189
+ HRDLKPQNLL++ Q+K+ DFG A+ + S + + +YRAP+++ G+
Sbjct: 159 AGVCHRDLKPQNLLVDPLTHQVKICDFGSAKQL-VKGEANISYICSRFYRAPELIFGATE 217
Query: 190 YCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQLAKYNPL 249
Y TSIDIWS GC+LAE+++G+PLFPG N +QL I +GTP + ++ NP
Sbjct: 218 YTTSIDIWSAGCVLAELLLGQPLFPGENAVDQLVEIIKVLGTPTRE------EIRCMNPH 271
Query: 250 LPP-HMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPWFAEYNHAN 308
P+ + + +D LLQ +P R +A +A HP+F E N
Sbjct: 272 YTDFRFPQIKAHPWHKIFHKRMPPEAIDFASRLLQYSPSLRCTALEACAHPFFDELREPN 331
>Hs22051130 [G] KOG0658 Glycogen synthase kinase-3
Length = 483
Score = 144 bits (364), Expect = 1e-34
Identities = 93/308 (30%), Positives = 159/308 (51%), Gaps = 30/308 (9%)
Query: 8 ETRFKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPSTAIREISLMKELKHD 67
E + ++ +GNG++ VY+ T VA+K+V D RE+ +M++L H
Sbjct: 116 EVAYTDIKVIGNGSFGVVYQARLAETRELVAIKKVLQDKRFKN-----RELQIMRKLDHC 170
Query: 68 NIVRLFDVIHTENK------LTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQL 121
NIVRL ++ + L LV E++ + + + K + + VK + +QL
Sbjct: 171 NIVRLRYFFYSSGEKKDELYLNLVLEYVPETVYRVARHFTKAKLT--IPILYVKVYMYQL 228
Query: 122 LQGVAFCHENRILHRDLKPQNLLIN-NRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRA 180
+ +A+ H + HRD+KPQNLL++ + LKL DFG A+ + S + + +YRA
Sbjct: 229 FRSLAYIHSQGVCHRDIKPQNLLVDPDTAVLKLCDFGSAKQL-VRGEPNVSYICSRYYRA 287
Query: 181 PDVLMGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQV 240
P+++ G+ +Y +SID+WS GC+LAE+++G+P+FPG + +QL I +GTP +
Sbjct: 288 PELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTRE----- 342
Query: 241 TQLAKYNP-----LLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDA 295
Q+ + NP P ++ ++ T + L LL+ P +RLS +A
Sbjct: 343 -QIREMNPNYTEFKFPQIKAHPWTKVFKSRT----PPEAIALCSSLLEYTPSSRLSPLEA 397
Query: 296 LNHPWFAE 303
H +F E
Sbjct: 398 CAHSFFDE 405
>Hs11995474 [G] KOG0658 Glycogen synthase kinase-3
Length = 483
Score = 144 bits (364), Expect = 1e-34
Identities = 93/308 (30%), Positives = 159/308 (51%), Gaps = 30/308 (9%)
Query: 8 ETRFKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPSTAIREISLMKELKHD 67
E + ++ +GNG++ VY+ T VA+K+V D RE+ +M++L H
Sbjct: 116 EVAYTDIKVIGNGSFGVVYQARLAETRELVAIKKVLQDKRFKN-----RELQIMRKLDHC 170
Query: 68 NIVRLFDVIHTENK------LTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQL 121
NIVRL ++ + L LV E++ + + + K + + VK + +QL
Sbjct: 171 NIVRLRYFFYSSGEKKDELYLNLVLEYVPETVYRVARHFTKAKLT--IPILYVKVYMYQL 228
Query: 122 LQGVAFCHENRILHRDLKPQNLLIN-NRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRA 180
+ +A+ H + HRD+KPQNLL++ + LKL DFG A+ + S + + +YRA
Sbjct: 229 FRSLAYIHSQGVCHRDIKPQNLLVDPDTAVLKLCDFGSAKQL-VRGEPNVSYICSRYYRA 287
Query: 181 PDVLMGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQV 240
P+++ G+ +Y +SID+WS GC+LAE+++G+P+FPG + +QL I +GTP +
Sbjct: 288 PELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTRE----- 342
Query: 241 TQLAKYNP-----LLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDA 295
Q+ + NP P ++ ++ T + L LL+ P +RLS +A
Sbjct: 343 -QIREMNPNYTEFKFPQIKAHPWTKVFKSRT----PPEAIALCSSLLEYTPSSRLSPLEA 397
Query: 296 LNHPWFAE 303
H +F E
Sbjct: 398 CAHSFFDE 405
>HsM4504163 [G] KOG0658 Glycogen synthase kinase-3
Length = 420
Score = 144 bits (363), Expect = 2e-34
Identities = 95/313 (30%), Positives = 161/313 (51%), Gaps = 30/313 (9%)
Query: 8 ETRFKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPSTAIREISLMKELKHD 67
E + + +GNG++ VY+ +G VA+K+V D RE+ +M++L H
Sbjct: 53 EVSYTDTKVIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKN-----RELQIMRKLDHC 107
Query: 68 NIVRLFDVIHTENK------LTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQL 121
NIVRL ++ + L LV +++ + + R+ + + L + VK + +QL
Sbjct: 108 NIVRLRYFFYSSGEKKDEVYLNLVLDYVPETVYRVA--RHYSRAKQTLPVIYVKLYMYQL 165
Query: 122 LQGVAFCHENRILHRDLKPQNLLIN-NRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRA 180
+ +A+ H I HRD+KPQNLL++ + LKL DFG A+ + S + + +YRA
Sbjct: 166 FRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQL-VRGEPNVSYICSRYYRA 224
Query: 181 PDVLMGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQV 240
P+++ G+ +Y +SID+WS GC+LAE+++G+P+FPG + +QL I +GTP +
Sbjct: 225 PELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTRE----- 279
Query: 241 TQLAKYNP-----LLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDA 295
Q+ + NP P ++ + T + L LL+ P ARL+ +A
Sbjct: 280 -QIREMNPNYTEFKFPQIKAHPWTKVFRPRT----PPEAIALCSRLLEYTPTARLTPLEA 334
Query: 296 LNHPWFAEYNHAN 308
H +F E N
Sbjct: 335 CAHSFFDELRDPN 347
>HsM20070143 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 424
Score = 144 bits (362), Expect = 2e-34
Identities = 93/306 (30%), Positives = 159/306 (51%), Gaps = 25/306 (8%)
Query: 10 RFKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPST-AIREISLMKELKHDN 68
R++QL+ +G+G V + G+ VA+K++ + T + A RE+ L+K + H N
Sbjct: 25 RYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRPFQNQTHAKRAYRELVLLKCVNHKN 84
Query: 69 IVRLFDVIHTENKLT------LVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLL 122
I+ L +V + L LV E MD +L + + H L+ + + Y +Q+L
Sbjct: 85 IISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVI--------HMELDHERMSYLLYQML 136
Query: 123 QGVAFCHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPD 182
G+ H I+HRDLKP N+++ + LK+ DFGLAR + VVT +YRAP+
Sbjct: 137 CGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLART-ACTNFMMTPYVVTRYYRAPE 195
Query: 183 VLMGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTP----VEQTWP 238
V++G Y ++DIWS GCI+ E++ G +F G++ +Q + + +GTP +++ P
Sbjct: 196 VILG-MGYKENVDIWSVGCIMGELVKGCVIFQGTDHIDQWNKVIEQLGTPSAEFMKKLQP 254
Query: 239 QVTQLAKYNPLLP----PHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKD 294
V + P P + D ++ +++ DLL +L ++PD R+S +
Sbjct: 255 TVRNYVENRPKYPGIKFEELFPDWIFPSESERDKIKTSQARDLLSKMLVIDPDKRISVDE 314
Query: 295 ALNHPW 300
AL HP+
Sbjct: 315 ALRHPY 320
>Hs21237739 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 382
Score = 144 bits (362), Expect = 2e-34
Identities = 93/306 (30%), Positives = 159/306 (51%), Gaps = 25/306 (8%)
Query: 10 RFKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPST-AIREISLMKELKHDN 68
R++QL+ +G+G V + G+ VA+K++ + T + A RE+ L+K + H N
Sbjct: 25 RYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRPFQNQTHAKRAYRELVLLKCVNHKN 84
Query: 69 IVRLFDVIHTENKLT------LVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLL 122
I+ L +V + L LV E MD +L + + H L+ + + Y +Q+L
Sbjct: 85 IISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVI--------HMELDHERMSYLLYQML 136
Query: 123 QGVAFCHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPD 182
G+ H I+HRDLKP N+++ + LK+ DFGLAR + VVT +YRAP+
Sbjct: 137 CGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLART-ACTNFMMTPYVVTRYYRAPE 195
Query: 183 VLMGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTP----VEQTWP 238
V++G Y ++DIWS GCI+ E++ G +F G++ +Q + + +GTP +++ P
Sbjct: 196 VILG-MGYKENVDIWSVGCIMGELVKGCVIFQGTDHIDQWNKVIEQLGTPSAEFMKKLQP 254
Query: 239 QVTQLAKYNPLLP----PHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKD 294
V + P P + D ++ +++ DLL +L ++PD R+S +
Sbjct: 255 TVRNYVENRPKYPGIKFEELFPDWIFPSESERDKIKTSQARDLLSKMLVIDPDKRISVDE 314
Query: 295 ALNHPW 300
AL HP+
Sbjct: 315 ALRHPY 320
>Hs21237736 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 424
Score = 144 bits (362), Expect = 2e-34
Identities = 93/306 (30%), Positives = 159/306 (51%), Gaps = 25/306 (8%)
Query: 10 RFKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPST-AIREISLMKELKHDN 68
R++QL+ +G+G V + G+ VA+K++ + T + A RE+ L+K + H N
Sbjct: 25 RYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRPFQNQTHAKRAYRELVLLKCVNHKN 84
Query: 69 IVRLFDVIHTENKLT------LVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLL 122
I+ L +V + L LV E MD +L + + H L+ + + Y +Q+L
Sbjct: 85 IISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVI--------HMELDHERMSYLLYQML 136
Query: 123 QGVAFCHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPD 182
G+ H I+HRDLKP N+++ + LK+ DFGLAR + VVT +YRAP+
Sbjct: 137 CGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLART-ACTNFMMTPYVVTRYYRAPE 195
Query: 183 VLMGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTP----VEQTWP 238
V++G Y ++DIWS GCI+ E++ G +F G++ +Q + + +GTP +++ P
Sbjct: 196 VILG-MGYKENVDIWSVGCIMGELVKGCVIFQGTDHIDQWNKVIEQLGTPSAEFMKKLQP 254
Query: 239 QVTQLAKYNPLLP----PHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKD 294
V + P P + D ++ +++ DLL +L ++PD R+S +
Sbjct: 255 TVRNYVENRPKYPGIKFEELFPDWIFPSESERDKIKTSQARDLLSKMLVIDPDKRISVDE 314
Query: 295 ALNHPW 300
AL HP+
Sbjct: 315 ALRHPY 320
>At2g30980 [G] KOG0658 Glycogen synthase kinase-3
Length = 412
Score = 144 bits (362), Expect = 2e-34
Identities = 96/300 (32%), Positives = 152/300 (50%), Gaps = 22/300 (7%)
Query: 17 VGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPSTAIREISLMKELKHDNIVRLFDVI 76
VG G++ V++ TG VA+K+V D RE+ LM+ + H N+V L
Sbjct: 78 VGTGSFGIVFQAKCLETGESVAIKKVLQDRRYKN-----RELQLMRLMDHPNVVSLKHCF 132
Query: 77 HT-----ENKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGVAFCHEN 131
+ E L LV E++ L + + + N + + VK + +Q+ +G+A+ H
Sbjct: 133 FSTTTRDELFLNLVMEYVPETLYRVLKHYTSSNQR--MPIFYVKLYTYQIFRGLAYIHTA 190
Query: 132 R-ILHRDLKPQNLLINN-RGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGSRN 189
+ HRD+KPQNLL++ Q KL DFG A+ + S + + +YRAP+++ G+
Sbjct: 191 PGVCHRDVKPQNLLVDPLTHQCKLCDFGSAKVL-VKGEANISYICSRYYRAPELIFGATE 249
Query: 190 YCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQLAKYNPL 249
Y +SIDIWS GC+LAE+++G+PLFPG N +QL I +GTP + ++ NP
Sbjct: 250 YTSSIDIWSAGCVLAELLLGQPLFPGENSVDQLVEIIKVLGTPTRE------EIRCMNPN 303
Query: 250 LPP-HMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPWFAEYNHAN 308
P+ + + +DL LLQ +P R +A +A HP+F E N
Sbjct: 304 YTDFRFPQIKAHPWHKVFHKRMPPEAIDLASRLLQYSPSLRCTALEACAHPFFNELREPN 363
>SPBC8D2.19 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 559
Score = 142 bits (358), Expect = 6e-34
Identities = 99/309 (32%), Positives = 163/309 (52%), Gaps = 31/309 (10%)
Query: 7 YETRFKQLEKVGNGTYATVYKGLNKT-TGVY--VALKEVKLDSEEGTPSTAIR---EISL 60
+E R+ +K+G+G++ TVY K G+Y VA+K++K S+ ++ ++L
Sbjct: 17 FEDRYLVKQKLGDGSFGTVYLAQRKEKNGLYETVAVKKLKNSSKPKPKHELLKLRESLAL 76
Query: 61 MKELKHDNIVRLFDV-IHTENKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQW 119
K KH ++ L + + + LV EFMD +L + R K +++
Sbjct: 77 RKISKHPCLIDLLETFMDPYRNIFLVMEFMDCNLFQLFKRRQGRLFTKETAFNILL---- 132
Query: 120 QLLQGVAFCHENRILHRDLKPQNLL--------INNRGQLKLGDFGLARAFGIPVNTFSS 171
Q++ G+ H++ +HRD+KP+N+L I++R +KLGDFGLAR + + +
Sbjct: 133 QIISGIEHIHKHGFMHRDIKPENILVKRISPKPISSRYSIKLGDFGLARP-SVSSDPLTE 191
Query: 172 EVVTLWYRAPDVLMGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGT 231
V T WYRAP++L+ S +Y S+D+++ GCI+ E+ KPLFPG N+ +QL + + +G
Sbjct: 192 YVSTRWYRAPELLLRSGSYNHSVDLYAFGCIVFEIYSLKPLFPGRNETDQLNRVCEILGN 251
Query: 232 P------VEQTWPQVTQLAK-YNPLLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQL 284
P W Q +LAK +LPP P +++LL N E ++ LL
Sbjct: 252 PGIDELDTLHYWSQAKELAKRLGFMLPPTKPYPIQKLLPQNCPE----GHAKMIPCLLAW 307
Query: 285 NPDARLSAK 293
NPD R +AK
Sbjct: 308 NPDVRPTAK 316
>ECU11g1290 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 328
Score = 142 bits (358), Expect = 6e-34
Identities = 89/296 (30%), Positives = 148/296 (49%), Gaps = 29/296 (9%)
Query: 11 FKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLD---SEEGTPSTAIREISLMKELKHD 67
++++ ++ +G++ VY+ KT ALK + G IRE+ ++K ++H
Sbjct: 26 YEKVCRISSGSFGNVYRVRRKTDNRVFALKRMNPSMCYDTNGFSILYIREVMILKHIRHR 85
Query: 68 NIVRLFDVIH--TENKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGV 125
NI+ + +V+ N +V E D DL+ + + K + M ++ Q+L+G+
Sbjct: 86 NIMEIEEVVEGCEINDFFIVMECCDTDLRSVIHSVGK------IGMKAARFLTCQMLKGL 139
Query: 126 AFCHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLM 185
F H I+HRDLKP N+L+ G L++ DFGLARA + ++ VVTLWYR ++L+
Sbjct: 140 KFLHGAGIVHRDLKPSNILLMRDGGLRIADFGLARAIE---SQMTNLVVTLWYRPIEILL 196
Query: 186 GSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQLAK 245
GS Y SID+WS GC++ EM+ G+P+ G + +QL IF +G P + A
Sbjct: 197 GSETYDESIDMWSVGCVVGEMLRGEPILAGEGEMDQLDRIFRLLGYPTD---------AD 247
Query: 246 YNPLLPPHM-----PRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDAL 296
+ L PH P + + + E + + LL +P R +A L
Sbjct: 248 FEGLDLPHFKNIRRPSTFEASFEGDF-ECYGEEAASFVRNLLSFDPRKRCTASQGL 302
>At2g23080 [TDK] KOG0668 Casein kinase II alpha subunit
Length = 333
Score = 142 bits (357), Expect = 8e-34
Identities = 92/310 (29%), Positives = 171/310 (54%), Gaps = 23/310 (7%)
Query: 7 YETRFKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPSTAIREISLMKEL-K 65
++ ++ + KVG G Y+ V++G N T +K +K ++ REI +++ L
Sbjct: 30 HQDDYEVVRKVGRGKYSEVFEGKNVNTNERCVIKILKPVKKKKIK----REIKILQNLCG 85
Query: 66 HDNIVRLFDVIHTENKLT--LVFEFMDN-DLKKFMDNRNKGNSHKGLEMDLVKYFQWQLL 122
NIV+L+D++ E+ T LVFEF+++ D K + ++Y+ ++LL
Sbjct: 86 GPNIVKLYDIVRDEHSKTPSLVFEFVNSVDFKVLYPTLTDYD---------IRYYIYELL 136
Query: 123 QGVAFCHENRILHRDLKPQNLLINNR-GQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAP 181
+ + FCH I+HRD+KP N++I+++ +L+L D+GLA F P ++ V + +++ P
Sbjct: 137 KALDFCHSQGIMHRDVKPHNVMIDHQLRKLRLIDWGLAE-FYHPGKEYNVRVASRYFKGP 195
Query: 182 DVLMGSRNYCTSIDIWSCGCILAEMIMGK-PLFPGSNDEEQLKLIFDTMGTPVEQTWPQV 240
++L+ ++Y S+D+WS GC+ A MI K P F G ++ +QL I +GT +
Sbjct: 196 ELLVDLQDYDYSLDMWSLGCMFAGMIFRKEPFFYGHDNHDQLVKIAKVLGTNELDHYLNK 255
Query: 241 TQL---AKYNPLLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALN 297
QL + L+ H+P+ + + + + ++ +D L LLQ + RL+A++A++
Sbjct: 256 YQLDLDPQLEALVGRHVPKPWSKFINADNQHLVSPEAIDFLDKLLQYDHQDRLTAREAMD 315
Query: 298 HPWFAEYNHA 307
HP+FA+ A
Sbjct: 316 HPYFAQVKAA 325
>CE27574 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 463
Score = 141 bits (356), Expect = 1e-33
Identities = 102/314 (32%), Positives = 159/314 (50%), Gaps = 31/314 (9%)
Query: 10 RFKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPST-AIREISLMKELKHDN 68
R++ L +G+G V + VA+K++ + T + A RE+ LM + H N
Sbjct: 118 RYQNLRLIGSGAQGIVCSAFDTVRNEQVAIKKLSRPFQNVTHAKRAYRELKLMSLVNHKN 177
Query: 69 IVRLFDVIHTENKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDL----VKYFQWQLLQG 124
I+ + + + KL EF NDL M+ + N + ++MDL + Y +Q+L G
Sbjct: 178 IIGILNCFTPQKKLD---EF--NDLYIVMELMD-ANLCQVIQMDLDHERLSYLLYQMLCG 231
Query: 125 VAFCHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVL 184
+ H I+HRDLKP N+++ + LK+ DFGLAR I + VVT +YRAP+V+
Sbjct: 232 IRHLHSAGIIHRDLKPSNIVVRSDCTLKILDFGLART-AIEAFMMTPYVVTRYYRAPEVI 290
Query: 185 MGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTP----VEQTWPQV 240
+G Y ++D+WS GCI E+I G+ LFPG + +Q I + +GTP +E+ P V
Sbjct: 291 LG-MGYKENVDVWSIGCIFGELIRGRVLFPGGDHIDQWTRIIEQLGTPDRSFLERLQPTV 349
Query: 241 TQLAKYNPLLPPHMPRDLKQLLQNNTEEVLDDN-------VVDLLHGLLQLNPDARLSAK 293
Y P + + L +N + D+ DLL +L ++P+ R+S
Sbjct: 350 ---RNYVENRPRYQATPFEVLFSDNMFPMTADSSRLTGAQARDLLSRMLVIDPERRISVD 406
Query: 294 DALNHP----WFAE 303
DAL HP WF E
Sbjct: 407 DALRHPYVNVWFDE 420
>CE17062 [T] KOG0660 Mitogen-activated protein kinase
Length = 448
Score = 140 bits (354), Expect = 2e-33
Identities = 98/346 (28%), Positives = 160/346 (45%), Gaps = 56/346 (16%)
Query: 11 FKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPST-AIREISLMKELKHDNI 69
+ L+ +G G Y V + TG VA+K+ + + RE+ L++ L+HDN+
Sbjct: 49 YNSLKPLGEGAYGVVCTAEYEPTGDRVAIKKFFRPFQSTIHAKRTYRELKLLRTLQHDNV 108
Query: 70 VRLFDVIHTE------NKLTLVFEFMDNDLKKFMDNRN-----------------KGNSH 106
+ + DV + N + V M +DL+ M + K SH
Sbjct: 109 LEMIDVFTPDPDASSLNNVYFVSVLMGSDLQNIMKIQRLTDEQIQLLIYQVLRGLKYMSH 168
Query: 107 KGLEMDLVKY-----FQWQLLQGVAFCHENRILHRDLKPQNLLINNRGQLKLG------- 154
+ ++ FQ + + + H I+HRDLKP N+ +N R ++K+
Sbjct: 169 QNFNSTIILKKLMHPFQRRNTRFRLYIHSAGIIHRDLKPSNIAVNERCEVKVFLSFSQLS 228
Query: 155 ----------DFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGSRNYCTSIDIWSCGCILA 204
DFGLARA + + V T WYRAP++++ +Y ++D+WS GCILA
Sbjct: 229 FLILSFFKILDFGLARAQDAEMTGY---VATRWYRAPEIMLNWMHYTQTVDVWSVGCILA 285
Query: 205 EMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQV--TQLAKYNPLLPPHMPRDLKQLL 262
E++ G+PLFPG + +QL I +GTP E+ W ++ + Y P + +D L
Sbjct: 286 ELVSGRPLFPGDDHIDQLTKIMSVVGTPKEEFWSKIQSEEARNYIKNRSPIIRQDFVTLF 345
Query: 263 QNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPWFAEYNHAN 308
+ ++LL +L L+PD R+S AL H + EY+ N
Sbjct: 346 -----PMASPYALELLEMMLILDPDRRISVSSALRHDYLREYSVPN 386
>Hs21361340 [G] KOG0658 Glycogen synthase kinase-3
Length = 433
Score = 140 bits (353), Expect = 2e-33
Identities = 96/321 (29%), Positives = 162/321 (49%), Gaps = 33/321 (10%)
Query: 8 ETRFKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPSTAIREISLMKELKHD 67
E + + +GNG++ VY+ +G VA+K+V D RE+ +M++L H
Sbjct: 53 EVSYTDTKVIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKN-----RELQIMRKLDHC 107
Query: 68 NIVRLFDVIHTENK------LTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQL 121
NIVRL ++ + L LV +++ + + R+ + + L + VK + +QL
Sbjct: 108 NIVRLRYFFYSSGEKKDEVYLNLVLDYVPETVYRVA--RHYSRAKQTLPVIYVKLYMYQL 165
Query: 122 LQGVAFCHENRILHRDLKPQNLLIN-NRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRA 180
+ +A+ H I HRD+KPQNLL++ + LKL DFG A+ + S + + +YRA
Sbjct: 166 FRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQL-VRGEPNVSYICSRYYRA 224
Query: 181 PDVLMGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTP----VEQT 236
P+++ G+ +Y +SID+WS GC+LAE+++G+P+FPG + +QL I +GTP + +
Sbjct: 225 PELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREM 284
Query: 237 WPQVTQL----AKYNPLLPP-----HMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPD 287
P T+ K +P H ++ E + L LL+ P
Sbjct: 285 NPNYTEFKFPQIKAHPWTKDSSGTGHFTSGVRVFRPRTPPE-----AIALCSRLLEYTPT 339
Query: 288 ARLSAKDALNHPWFAEYNHAN 308
ARL+ +A H +F E N
Sbjct: 340 ARLTPLEACAHSFFDELRDPN 360
>Hs4506081 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 422
Score = 139 bits (351), Expect = 4e-33
Identities = 96/306 (31%), Positives = 152/306 (49%), Gaps = 25/306 (8%)
Query: 10 RFKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPST-AIREISLMKELKHDN 68
R++ L+ +G+G V + VA+K++ + T + A RE+ LMK + H N
Sbjct: 63 RYQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKN 122
Query: 69 IVRLFDVIHTENKLT------LVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLL 122
I+ L +V + L LV E MD +L + + L+ + + Y +Q+L
Sbjct: 123 IISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQME--------LDHERMSYLLYQML 174
Query: 123 QGVAFCHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPD 182
G+ H I+HRDLKP N+++ + LK+ DFGLAR G + VVT +YRAP+
Sbjct: 175 CGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSF-MMTPYVVTRYYRAPE 233
Query: 183 VLMGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQ--- 239
V++G Y ++DIWS GCI+ EM+ K LFPG + +Q + + +GTP + +
Sbjct: 234 VILG-MGYKENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKLQP 292
Query: 240 -----VTQLAKYNPLLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKD 294
V KY L P + D + ++ DLL +L ++P R+S D
Sbjct: 293 TVRNYVENRPKYAGLTFPKLFPDSLFPADSEHNKLKASQARDLLSKMLVIDPAKRISVDD 352
Query: 295 ALNHPW 300
AL HP+
Sbjct: 353 ALQHPY 358
>Hs20986510 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 464
Score = 139 bits (351), Expect = 4e-33
Identities = 96/306 (31%), Positives = 152/306 (49%), Gaps = 25/306 (8%)
Query: 10 RFKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPST-AIREISLMKELKHDN 68
R++ L+ +G+G V + VA+K++ + T + A RE+ LMK + H N
Sbjct: 63 RYQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKN 122
Query: 69 IVRLFDVIHTENKLT------LVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLL 122
I+ L +V + L LV E MD +L + + L+ + + Y +Q+L
Sbjct: 123 IISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQME--------LDHERMSYLLYQML 174
Query: 123 QGVAFCHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPD 182
G+ H I+HRDLKP N+++ + LK+ DFGLAR G + VVT +YRAP+
Sbjct: 175 CGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSF-MMTPYVVTRYYRAPE 233
Query: 183 VLMGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQ--- 239
V++G Y ++DIWS GCI+ EM+ K LFPG + +Q + + +GTP + +
Sbjct: 234 VILG-MGYKENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKLQP 292
Query: 240 -----VTQLAKYNPLLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKD 294
V KY L P + D + ++ DLL +L ++P R+S D
Sbjct: 293 TVRNYVENRPKYAGLTFPKLFPDSLFPADSEHNKLKASQARDLLSKMLVIDPAKRISVDD 352
Query: 295 ALNHPW 300
AL HP+
Sbjct: 353 ALQHPY 358
>Hs20986506 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 426
Score = 139 bits (351), Expect = 4e-33
Identities = 96/306 (31%), Positives = 152/306 (49%), Gaps = 25/306 (8%)
Query: 10 RFKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPST-AIREISLMKELKHDN 68
R++ L+ +G+G V + VA+K++ + T + A RE+ LMK + H N
Sbjct: 25 RYQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKN 84
Query: 69 IVRLFDVIHTENKLT------LVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLL 122
I+ L +V + L LV E MD +L + + L+ + + Y +Q+L
Sbjct: 85 IISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQME--------LDHERMSYLLYQML 136
Query: 123 QGVAFCHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPD 182
G+ H I+HRDLKP N+++ + LK+ DFGLAR G + VVT +YRAP+
Sbjct: 137 CGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSF-MMTPYVVTRYYRAPE 195
Query: 183 VLMGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQ--- 239
V++G Y ++DIWS GCI+ EM+ K LFPG + +Q + + +GTP + +
Sbjct: 196 VILG-MGYKENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKLQP 254
Query: 240 -----VTQLAKYNPLLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKD 294
V KY L P + D + ++ DLL +L ++P R+S D
Sbjct: 255 TVRNYVENRPKYAGLTFPKLFPDSLFPADSEHNKLKASQARDLLSKMLVIDPAKRISVDD 314
Query: 295 ALNHPW 300
AL HP+
Sbjct: 315 ALQHPY 320
>At4g00720 [G] KOG0658 Glycogen synthase kinase-3
Length = 472
Score = 139 bits (350), Expect = 5e-33
Identities = 93/300 (31%), Positives = 156/300 (52%), Gaps = 22/300 (7%)
Query: 17 VGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPSTAIREISLMKELKHDNIVRL-FDV 75
VG G++ V++ TG VA+K+V D RE+ +M+ H N+VRL
Sbjct: 144 VGTGSFGVVFQAKCLETGEQVAIKKVLQDKRYKN-----RELQIMRLQDHPNVVRLRHSF 198
Query: 76 IHTENK----LTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGVAFCHEN 131
T +K L LV E++ + + + K N H + + V+ + +Q+ + + + H
Sbjct: 199 FSTTDKDELYLNLVLEYVPETVYRASKHYTKMNQH--MPIIFVQLYTYQICRALNYLHRV 256
Query: 132 -RILHRDLKPQNLLINNRG-QLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGSRN 189
+ HRD+KPQNLL+N + QLK+ DFG A+ +P S + + +YRAP+++ G+
Sbjct: 257 VGVCHRDIKPQNLLVNPQTHQLKICDFGSAKML-VPGEPNISYICSRYYRAPELIFGATE 315
Query: 190 YCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQLAKYNPL 249
Y +ID+WS GC++AE+++G+PLFPG + +QL I +GTP + ++ NP
Sbjct: 316 YTNAIDMWSGGCVMAELLLGQPLFPGESGIDQLVEIIKILGTPTRE------EIRCMNPN 369
Query: 250 LPP-HMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPWFAEYNHAN 308
P+ + + VDL+ LLQ +P+ R +A +A HP+F + N
Sbjct: 370 YTEFKFPQIKAHPWHKIFHKRMPPEAVDLVSRLLQYSPNLRCTALEACAHPFFDDLRDPN 429
>YKL161c [T] KOG0660 Mitogen-activated protein kinase
Length = 433
Score = 137 bits (346), Expect = 2e-32
Identities = 92/308 (29%), Positives = 166/308 (53%), Gaps = 31/308 (10%)
Query: 16 KVGNGTYATV----YKGLNKTTGVYVALKEV-KLDSEEGTPSTAIREISLMKELK-HDNI 69
K+G G+++ + Y N+ T +VA++++ + + +RE+ L++ L+ H NI
Sbjct: 28 KIGRGSHSLICSSTYTESNEET--HVAIRKIPNAFGNKLSCKRTLRELKLLRHLRGHPNI 85
Query: 70 VRLFD---VIHTENKLTLVF---EFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQ 123
V LFD V + L V+ E M+ DL + + S + LE + F +Q+L
Sbjct: 86 VWLFDTDIVFYPNGALNGVYLYEELMECDLSQII------RSEQRLEDAHFQSFIYQILC 139
Query: 124 GVAFCHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFG----IPVNTFSSEVVTLWYR 179
+ + H +LH DLKP+NLL+N+ QLK+ +FGL+ ++ + + ++WY+
Sbjct: 140 ALKYIHSANVLHCDLKPKNLLVNSDCQLKICNFGLSCSYSENHKVNDGFIKGYITSIWYK 199
Query: 180 APDVLMGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQ 239
AP++L+ + ++DIWS GCILAE++ KP+F G + + L I +GTP E+T +
Sbjct: 200 APEILLNYQECTKAVDIWSTGCILAELLGRKPMFEGKDYVDHLNHILQILGTPPEETLQE 259
Query: 240 VTQLAKYNPLLP-PHMP-RDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALN 297
+ YN + ++P R + +L E L +LL +L+ +P R++ +DAL
Sbjct: 260 IASQKVYNYIFQFGNIPGRSFESILPGANPEAL-----ELLKKMLEFDPKKRITVEDALE 314
Query: 298 HPWFAEYN 305
HP+ + ++
Sbjct: 315 HPYLSMWH 322
>CE29318 [T] KOG0660 Mitogen-activated protein kinase
Length = 474
Score = 137 bits (346), Expect = 2e-32
Identities = 87/318 (27%), Positives = 162/318 (50%), Gaps = 27/318 (8%)
Query: 7 YETRFKQLEKVGNGTYATVYK-------GLNKTTGVYVALKEVKLDSEEGTPSTAI-REI 58
Y+ +E +G G++ V K GL + YVA+K+++ + + I RE
Sbjct: 114 YDVEPNSIEYLGGGSFGNVIKTSAVCRDGLRR----YVAIKKMREPFFDPHHARRIFRET 169
Query: 59 SLMKELKHDNIVRLFDVIHTENK-----LTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDL 113
L++ ++HDNI+ D+ + + + +V EF L + + + + + L +
Sbjct: 170 KLLQLMRHDNIICALDIYTPDEENDFRDVYVVTEFAGRSLYQIL-KQQRDYGRRVLTDEH 228
Query: 114 VKYFQWQLLQGVAFCHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEV 173
+K+ +Q+++ + + H I+HRDLKP NL + + L + DFGLAR+ + + V
Sbjct: 229 IKFIIYQIIRALKYIHSANIIHRDLKPGNLALTDDSDLMILDFGLARSLEKKDTSLTQYV 288
Query: 174 VTLWYRAPDVLMGS-RNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTP 232
T WYR+P+V+ +Y D+WS GCI AE++ G+PLFPG Q + I G+P
Sbjct: 289 QTRWYRSPEVIYWKIDSYTNLADMWSLGCIAAELLTGEPLFPGDEPNAQYQRITQLCGSP 348
Query: 233 VEQTWPQV-----TQLAKYNPLLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPD 287
E+ ++ + + H R+ + + + ++ +DLL LL L+P+
Sbjct: 349 DEELLTKIENDNSSAIKAVIQSYTTHKRRNFRDVFSAHNP---SEDFIDLLEKLLVLDPE 405
Query: 288 ARLSAKDALNHPWFAEYN 305
R++ ++A+ HP+ AE++
Sbjct: 406 KRITVEEAIQHPYLAEFS 423
>At5g14640 [G] KOG0658 Glycogen synthase kinase-3
Length = 408
Score = 137 bits (346), Expect = 2e-32
Identities = 95/304 (31%), Positives = 155/304 (50%), Gaps = 32/304 (10%)
Query: 17 VGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPSTAIREISLMKELKHDNIVRLFDVI 76
VG G++ V++ TG VA+K+V D RE+ M+ L H N+V L
Sbjct: 80 VGQGSFGIVFQAKCLETGETVAIKKVLQDKRYKN-----RELQTMRLLDHPNVVSLKHCF 134
Query: 77 HTENK-----LTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGVAFCHEN 131
+ + L LV E++ + + + ++ N + + VK + +Q+ + +A+ H
Sbjct: 135 FSTTEKDELYLNLVLEYVPETVYRVSKHYSRANQR--MPIIYVKLYTYQICRALAYIHGG 192
Query: 132 -RILHRDLKPQNLLIN-NRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGSRN 189
+ HRD+KPQNLL+N + Q+KL DFG A+ + S + + +YRAP+++ G+
Sbjct: 193 VGVCHRDIKPQNLLVNPHTHQVKLCDFGSAKVL-VKGEPNISYICSRYYRAPELIFGATE 251
Query: 190 YCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQLAKYNP- 248
Y T+IDIWS GC+LAE+++G+PLFPG + +QL I +GTP + ++ NP
Sbjct: 252 YTTTIDIWSAGCVLAELLLGQPLFPGESGVDQLVEIIKVLGTPTRE------EIKCMNPN 305
Query: 249 ----LLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPWFAEY 304
P ++ T VDL+ LLQ +P+ R +A A+ HP+F E
Sbjct: 306 YTEFKFPQIKAHPWHKIFHKRT----PPEAVDLVSRLLQYSPNLRSTA--AIVHPFFDEL 359
Query: 305 NHAN 308
N
Sbjct: 360 RDPN 363
>At3g61160 [G] KOG0658 Glycogen synthase kinase-3
Length = 431
Score = 137 bits (345), Expect = 2e-32
Identities = 89/292 (30%), Positives = 150/292 (50%), Gaps = 20/292 (6%)
Query: 17 VGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPSTAIREISLMKELKHDNIVRL-FDV 75
+G G++ V++ T VA+K+V D RE+ +M+ L H N+V L
Sbjct: 108 IGTGSFGVVFQAKCLETEEKVAIKKVLQDKRYKN-----RELQIMRMLDHPNVVELKHSF 162
Query: 76 IHTENK----LTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGVAFCHEN 131
T K L LV E++ + + + K N H + + ++ + +Q+ + + + H+
Sbjct: 163 FSTTEKDELYLNLVLEYVPETIYRASRSYTKMNQH--MPLIYIQLYTYQICRAMNYLHQV 220
Query: 132 -RILHRDLKPQNLLINN-RGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGSRN 189
+ HRD+KPQNLL+NN ++K+ DFG A+ IP S + + +YRAP+++ G+
Sbjct: 221 VGVCHRDIKPQNLLVNNVTHEVKICDFGSAKML-IPGEPNISYICSRYYRAPELIFGATE 279
Query: 190 YCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQLAKYNPL 249
Y ++ID+WS GC++AE+ +G PLFPG +QL I +GTP + + +YN
Sbjct: 280 YTSAIDMWSVGCVMAELFLGHPLFPGETSVDQLVEIIKILGTPAREEIKNMN--PRYNDF 337
Query: 250 LPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPWF 301
P+ Q + +DL LLQ +P+ R +A +A HP+F
Sbjct: 338 ---KFPQIKAQPWHKIFRRQVSPEAMDLASRLLQYSPNLRCTALEACAHPFF 386
>7297631 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 372
Score = 137 bits (345), Expect = 2e-32
Identities = 100/313 (31%), Positives = 155/313 (48%), Gaps = 36/313 (11%)
Query: 9 TRFKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPST-AIREISLMKELKHD 67
+R+ L +G+G V + T VA+K++ + T + A RE LMK + H
Sbjct: 22 SRYINLRPIGSGAQGIVCAAYDTITQQNVAIKKLSRPFQNVTHAKRAYREFKLMKLVNHK 81
Query: 68 NIVRLFDVIHTENKLT------LVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQL 121
NI+ L + + L LV E MD +L + + L+ D + Y +Q+
Sbjct: 82 NIIGLLNAFTPQRNLEEFQDVYLVMELMDANLCQVIQ--------MDLDHDRMSYLLYQM 133
Query: 122 LQGVAFCHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAP 181
L G+ H I+HRDLKP N+++ LK+ DFGLAR G + VVT +YRAP
Sbjct: 134 LCGIKHLHSAGIIHRDLKPSNIVVKADCTLKILDFGLARTAGTTF-MMTPYVVTRYYRAP 192
Query: 182 DVLMGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTP----VEQTW 237
+V++G Y ++DIWS GCI+ EMI G LFPG++ +Q I + +GTP +++
Sbjct: 193 EVILG-MGYTENVDIWSVGCIMGEMIRGGVLFPGTDHIDQWNKIIEQLGTPSPSFMQRLQ 251
Query: 238 PQVTQLAKYNP---------LLPPHM-PRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPD 287
P V + P L P + P D QN+ + D +LL +L ++P+
Sbjct: 252 PTVRNYVENRPRYTGYSFDRLFPDGLFPNDNN---QNSRRKASDAR--NLLSKMLVIDPE 306
Query: 288 ARLSAKDALNHPW 300
R+S +AL H +
Sbjct: 307 QRISVDEALKHEY 319
>SPAC23C11.11 [TDK] KOG0668 Casein kinase II alpha subunit
Length = 332
Score = 136 bits (342), Expect = 4e-32
Identities = 91/312 (29%), Positives = 166/312 (53%), Gaps = 27/312 (8%)
Query: 1 MSPLLRYETRFKQLEKVGNGTYATVYKGLNKTTG---VYVALKEVKLDSEEGTPSTAIRE 57
M + Y+ ++ + KVG G Y+ V++GLN + LK VK + RE
Sbjct: 33 MQEVFGYQDNYEIIRKVGRGKYSEVFEGLNVLNNSKCIIKVLKPVKYKKIK-------RE 85
Query: 58 ISLMKELKHD-NIVRLFDVIHTENKLT--LVFEFMDNDLKKFMDNRNKGNSHKGLEMDLV 114
I +++ L NI+ L D++ T L+FEF+DN +D R + + +
Sbjct: 86 IKILQNLAGGPNIISLLDIVRDPESKTPSLIFEFVDN-----IDFRTLYPTLSDYD---I 137
Query: 115 KYFQWQLLQGVAFCHENRILHRDLKPQNLLINN-RGQLKLGDFGLARAFGIPVNTFSSEV 173
+Y+ ++LL+ + FCH I+HRD+KP N++I++ + +L+L D+GLA + + ++ V
Sbjct: 138 RYYSYELLKALDFCHSRGIMHRDVKPHNVMIDHKKRKLRLIDWGLAEFYHAGME-YNVRV 196
Query: 174 VTLWYRAPDVLMGSRNYCTSIDIWSCGCILAEMIMGK-PLFPGSNDEEQLKLIFDTMGTP 232
+ +++ P++L+ R Y S+DIWS G + A +I K F G ++ +QL I +GT
Sbjct: 197 ASRYFKGPELLVDFREYDYSLDIWSFGVMFAALIFKKDTFFRGRDNYDQLVKIAKVLGTD 256
Query: 233 VEQTWPQVTQLA---KYNPLLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDAR 289
+ Q Q+ +Y+ +L + RD + + + +D +DLL+ LL+ + R
Sbjct: 257 ELFAYVQKYQIVLDRQYDNILGQYPKRDWYSFVNRDNRSLANDEAIDLLNRLLRYDHQER 316
Query: 290 LSAKDALNHPWF 301
L+ ++A+ HP+F
Sbjct: 317 LTCQEAMAHPYF 328
>Hs4503429 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 553
Score = 135 bits (339), Expect = 1e-31
Identities = 100/329 (30%), Positives = 167/329 (50%), Gaps = 47/329 (14%)
Query: 10 RFKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPSTAIREISLMKELKHDNI 69
R++ L+ +G G++ V + + YVALK V+ +E+ A EI +++ LK +
Sbjct: 173 RYEVLKIIGKGSFGQVARVYDHKLRQYVALKMVR--NEKRFHRQAAEEIRILEHLKKQDK 230
Query: 70 VRLFDVIHT------ENKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQ 123
+VIH N + + FE + DL + + K N +G + LV+ F +LQ
Sbjct: 231 TGSMNVIHMLESFTFRNHVCMAFELLSIDLYELI----KKNKFQGFSVQLVRKFAQSILQ 286
Query: 124 GVAFCHENRILHRDLKPQNLLINNRGQ--LKLGDFGLARAFGIPVNTFSSEVVTLWYRAP 181
+ H+N+I+H DLKP+N+L+ + G+ K+ DFG + + T+ + + +YRAP
Sbjct: 287 SLDALHKNKIIHCDLKPENILLKHHGRSSTKVIDFGSSCFEYQKLYTY---IQSRFYRAP 343
Query: 182 DVLMGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVT 241
++++GSR Y T IDIWS CILAE++ G+PLFPG ++ +QL + + +G P + Q +
Sbjct: 344 EIILGSR-YSTPIDIWSFRCILAELLTGQPLFPGEDEGDQLACMMELLGMPPPKLLEQ-S 401
Query: 242 QLAKYNPLLPPHMPRDLKQLLQNNTEEVL--------------------------DDNV- 274
+ AKY + +PR Q + VL DD +
Sbjct: 402 KRAKYF-INSKGIPRYCSVTTQADGRVVLVGGRSRRGKKRGPPGSKDWGTALKGCDDYLF 460
Query: 275 VDLLHGLLQLNPDARLSAKDALNHPWFAE 303
++ L L +P ARL+ AL HPW ++
Sbjct: 461 IEFLKRCLHWDPSARLTPAQALRHPWISK 489
>YPR054w [T] KOG0660 Mitogen-activated protein kinase
Length = 388
Score = 134 bits (337), Expect = 2e-31
Identities = 99/313 (31%), Positives = 161/313 (50%), Gaps = 31/313 (9%)
Query: 11 FKQLEKVGNGTYATV----YKGLNKTTGVYVALKEVK-LDSEEGTPSTAIREISLMKELK 65
++ ++ +G G Y TV +KG ++ +A+K++ + ++E AIRE+ M K
Sbjct: 38 YEIIQFLGKGAYGTVCSVKFKG--RSPAARIAVKKISNIFNKEILLKRAIRELKFMNFFK 95
Query: 66 -HDNIVRLFDV-IHTENKLTLVF---EFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQ 120
H NIV L D+ I T + ++ E +D DL K + +S L +KYF +Q
Sbjct: 96 GHKNIVNLIDLEIVTSSPYDGLYCYQELIDYDLAKVI------HSSVQLSEFHIKYFLYQ 149
Query: 121 LLQGVAFCHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTF----------S 170
+L G+ + H ++HRDLKP N+L G LK+ DFGLAR GI F +
Sbjct: 150 ILCGLKYIHSADVIHRDLKPGNILCTLNGCLKICDFGLAR--GIHAGFFKCHSTVQPHIT 207
Query: 171 SEVVTLWYRAPDVLMGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMG 230
+ V T WYRAP++L+ ++ Y S+DIW+ GCILAE KP+F G + Q+ I +G
Sbjct: 208 NYVATRWYRAPELLLSNQPYSKSVDIWAVGCILAEFYARKPVFMGRDSMHQIFEIIKVLG 267
Query: 231 TPVEQTWPQVTQLAKYNPLLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARL 290
TP + + + +N + P K++ +N ++L+ LL + RL
Sbjct: 268 TPDKDILIKFGTIKAWNLGKNSNNP-VYKKIPWSNIFPFASHEAINLIESLLHWDSTHRL 326
Query: 291 SAKDALNHPWFAE 303
+ + A++HP+ E
Sbjct: 327 NVEQAISHPFLNE 339
>YJL141c [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 807
Score = 134 bits (337), Expect = 2e-31
Identities = 100/347 (28%), Positives = 176/347 (49%), Gaps = 61/347 (17%)
Query: 10 RFKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPSTAIREISLMKELKHD-- 67
++ L+ +G GT+ V K N T +A+K VK +E T S +I + K D
Sbjct: 368 KYLVLDILGQGTFGQVVKCQNLLTKEILAVKVVKSRTEYLTQSITEAKILELLNQKIDPT 427
Query: 68 ---NIVRLFDVIHTENKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQG 124
+ +R++D +N L LVFE + N+L + + K N GL + L++ F Q+L
Sbjct: 428 NKHHFLRMYDSFVHKNHLCLVFELLSNNLYELL----KQNKFHGLSIQLIRTFTTQILDS 483
Query: 125 VAFCHENRILHRDLKPQNLLI--NNRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPD 182
+ E++++H DLKP+N+L+ ++ +LK+ DFG + V T+ + + +YRAP+
Sbjct: 484 LCVLKESKLIHCDLKPENILLCAPDKPELKIIDFGSSCEEARTVYTY---IQSRFYRAPE 540
Query: 183 VLMGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTP---------- 232
+++G Y TSID+WS GCI+AE+ +G P+FPG+++ QL I DT+G P
Sbjct: 541 IILGIP-YSTSIDMWSLGCIVAELFLGIPIFPGASEYNQLTRIIDTLGYPPSWMIDMGKN 599
Query: 233 ----VEQTWPQVTQLA--------------KYNPLLPPHMP----RDLKQLLQN------ 264
+++ P+ + + +YN + P R L +++N
Sbjct: 600 SGKFMKKLAPEESSSSTQKHRMKTIEEFCREYNIVEKPSKQYFKWRKLPDIIRNYRYPKS 659
Query: 265 --NTEEVLDDN------VVDLLHGLLQLNPDARLSAKDALNHPWFAE 303
N++E++D ++ L G+L LNP R + + A+ HP+ +
Sbjct: 660 IQNSQELIDQEMQNRECLIHFLGGVLNLNPLERWTPQQAMLHPFITK 706
>Hs20986521 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 427
Score = 134 bits (336), Expect = 2e-31
Identities = 91/306 (29%), Positives = 153/306 (49%), Gaps = 25/306 (8%)
Query: 10 RFKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPST-AIREISLMKELKHDN 68
R++ L+ +G+G V + VA+K++ + T + A RE+ LMK + H N
Sbjct: 25 RYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKN 84
Query: 69 IVRLFDVIHTENKLT------LVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLL 122
I+ L +V + L +V E MD +L + + L+ + + Y +Q+L
Sbjct: 85 IIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQME--------LDHERMSYLLYQML 136
Query: 123 QGVAFCHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPD 182
G+ H I+HRDLKP N+++ + LK+ DFGLAR G + VVT +YRAP+
Sbjct: 137 CGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSF-MMTPYVVTRYYRAPE 195
Query: 183 VLMGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQ 242
V++G Y ++DIWS GCI+ EMI G LFPG++ +Q + + +GTP + ++
Sbjct: 196 VILG-MGYKENVDIWSVGCIMGEMIKGGVLFPGTDHIDQWNKVIEQLGTPCPEFMKKLQP 254
Query: 243 LAK-YNPLLPPHMPRDLKQLL-------QNNTEEVLDDNVVDLLHGLLQLNPDARLSAKD 294
+ Y P + ++L + ++ DLL +L ++ R+S +
Sbjct: 255 TVRTYVENRPKYAGYSFEKLFPDVLFPADSEHNKLKASQARDLLSKMLVIDASKRISVDE 314
Query: 295 ALNHPW 300
AL HP+
Sbjct: 315 ALQHPY 320
>Hs20986519 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 384
Score = 134 bits (336), Expect = 2e-31
Identities = 91/306 (29%), Positives = 153/306 (49%), Gaps = 25/306 (8%)
Query: 10 RFKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPST-AIREISLMKELKHDN 68
R++ L+ +G+G V + VA+K++ + T + A RE+ LMK + H N
Sbjct: 25 RYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKN 84
Query: 69 IVRLFDVIHTENKLT------LVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLL 122
I+ L +V + L +V E MD +L + + L+ + + Y +Q+L
Sbjct: 85 IIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQME--------LDHERMSYLLYQML 136
Query: 123 QGVAFCHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPD 182
G+ H I+HRDLKP N+++ + LK+ DFGLAR G + VVT +YRAP+
Sbjct: 137 CGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSF-MMTPYVVTRYYRAPE 195
Query: 183 VLMGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQ 242
V++G Y ++DIWS GCI+ EMI G LFPG++ +Q + + +GTP + ++
Sbjct: 196 VILG-MGYKENVDIWSVGCIMGEMIKGGVLFPGTDHIDQWNKVIEQLGTPCPEFMKKLQP 254
Query: 243 LAK-YNPLLPPHMPRDLKQLL-------QNNTEEVLDDNVVDLLHGLLQLNPDARLSAKD 294
+ Y P + ++L + ++ DLL +L ++ R+S +
Sbjct: 255 TVRTYVENRPKYAGYSFEKLFPDVLFPADSEHNKLKASQARDLLSKMLVIDASKRISVDE 314
Query: 295 ALNHPW 300
AL HP+
Sbjct: 315 ALQHPY 320
>Hs21361643 [T] KOG4717 Serine/threonine protein kinase
Length = 765
Score = 133 bits (335), Expect = 3e-31
Identities = 91/289 (31%), Positives = 146/289 (50%), Gaps = 47/289 (16%)
Query: 17 VGNGTYATVYKGLNKTTGVYVALKEV---KLDSEEGTPSTAIREISLMKELKHDNIVRLF 73
+G G +A V + TG VA+K + KLD+ +E+ MK ++H NIVRL+
Sbjct: 22 LGRGHFAVVKLARHVFTGEKVAVKVIDKTKLDTL--ATGHLFQEVRCMKLVQHPNIVRLY 79
Query: 74 DVIHTENKLTLVFEFMDN-DLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGVAFCHENR 132
+VI T+ KL L+ E D D+ ++ +G L DL K + Q++ +++CH+
Sbjct: 80 EVIDTQTKLYLILELGDEGDMFDYIMKHEEG-----LNEDLPKKYFAQIVHAISYCHKLH 134
Query: 133 ILHRDLKPQNLLI-NNRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGSRNYC 191
++HRDLKP+N++ +G +KL DFG + F P ++ +L Y AP++L+G
Sbjct: 135 VVHRDLKPENVVFFEKQGLVKLTDFGFSNKFQ-PGKKLTTSCGSLAYSAPEILLGDEYDA 193
Query: 192 TSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQLAKYNPLLP 251
++DIWS G IL ++ G+P F +ND E L +I D KY +P
Sbjct: 194 PAVDIWSLGVILFMLVCGQPPFQEANDSETLTMIMD----------------CKYT--VP 235
Query: 252 PHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPW 300
H+ ++ K DL+ +LQ +P R S ++ NHPW
Sbjct: 236 SHVSKECK----------------DLITRMLQRDPKRRASLEEIENHPW 268
>Hs18552621 [R] KOG0597 Serine-threonine protein kinase FUSED
Length = 1315
Score = 133 bits (335), Expect = 3e-31
Identities = 94/294 (31%), Positives = 141/294 (46%), Gaps = 42/294 (14%)
Query: 10 RFKQLEKVGNGTYATVYKGLNKTTGVYVALKEV-KLDSEEGTPSTAIREISLMKELKHDN 68
++ LE +G G++ VYKG K + VALK + KL E REI +M+ L+H N
Sbjct: 3 KYHVLEMIGEGSFGRVYKGRRKYSAQVVALKFIPKLGRSEKELRNLQREIEIMRGLRHPN 62
Query: 69 IVRLFDVIHTENKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGVAFC 128
IV + D T+ ++ +V ++ + +L + +++ K L D V+ QL+ + +
Sbjct: 63 IVHMLDSFETDKEVVVVTDYAEGELFQILEDDGK------LPEDQVQAIAAQLVSALYYL 116
Query: 129 HENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGSR 188
H +RILHRD+KPQN+L+ G +KL DFG ARA +S T Y +P+ L+ R
Sbjct: 117 HSHRILHRDMKPQNILLAKGGGIKLCDFGFARAMSTNTMVLTSIKGTPLYMSPE-LVEER 175
Query: 189 NYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQLAKYNP 248
Y + D+WS GCIL E+ +G P F ++ + + LI + PV WP N
Sbjct: 176 PYDHTADLWSVGCILYELAVGTPPFYATSIFQLVSLI---LKDPVR--WPSTISPCFKN- 229
Query: 249 LLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPWFA 302
L GLL +P RLS D L HP+ A
Sbjct: 230 ----------------------------FLQGLLTKDPRQRLSWPDLLYHPFIA 255
>ECU05g1510 [TDK] KOG0668 Casein kinase II alpha subunit
Length = 319
Score = 133 bits (334), Expect = 4e-31
Identities = 92/298 (30%), Positives = 162/298 (53%), Gaps = 23/298 (7%)
Query: 10 RFKQLEKVGNGTYATVYKGLNKTTGVYV-ALKEVKLDSEEGTPSTAIREISLMKELKHDN 68
+++ +++G G Y+ V++G + + ALK V+ + RE+ +++ L H N
Sbjct: 36 KYQIYQRMGRGKYSEVFEGRKDREKIVIKALKPVR-------KAKICREVLILRNLSHKN 88
Query: 69 IVRLFDVI-HTENKL-TLVFEFMDN-DLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGV 125
I++L DV+ E+++ +L+FE++++ D K + K D+V+Y + Q+L +
Sbjct: 89 IIKLMDVVVDPESQIYSLIFEYIEHEDYAKIFE--------KLCYKDIVEYSR-QILSAL 139
Query: 126 AFCHENRILHRDLKPQNLLINN-RGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVL 184
++CH I+HRD+KPQN++IN R +LK+ D+GLA F P +S V + +Y+ P++L
Sbjct: 140 SYCHSMGIIHRDIKPQNMVINQARRELKIIDWGLAE-FYHPKKEYSVRVASRYYKGPELL 198
Query: 185 MGSRNYCTSIDIWSCGCILAEMIMGK-PLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQL 243
+ Y S+DIWS GC+LAE++ K P F G ++ +QL I +G + + + ++
Sbjct: 199 VDYPYYDYSLDIWSFGCVLAELVFKKRPFFHGESNSDQLVKIARILGYTHLKKYVRKYKM 258
Query: 244 AKYNPLLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPWF 301
A NP R L + L N +DLL +L + R +A + L HP F
Sbjct: 259 APLNPKYEGVGERVLLSSFTPPGKTGLYTNAIDLLEKILIYDHQDRPTADECLRHPLF 316
>CE05377 [G] KOG0658 Glycogen synthase kinase-3
Length = 381
Score = 133 bits (334), Expect = 4e-31
Identities = 91/313 (29%), Positives = 155/313 (49%), Gaps = 38/313 (12%)
Query: 19 NGTYATVYKGLNKTTGVY---VALKEVKLDSEEGTPSTAIREISLMKELKHDNIVRLFDV 75
+G ++ VY+G+ +T + + +K+ +G P ++ + + +LKH NIVRL
Sbjct: 34 SGAFSNVYRGIARTESNHQMEIVIKKT-WPRHKGCP-LEVKILGKLGKLKHKNIVRLLFS 91
Query: 76 IHTENK----LTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGVAFCHEN 131
+++ L L+FE++ +L +F+ + N+ +++ VK WQL +G A ++
Sbjct: 92 YQKQHEGRICLGLIFEYIPMNLHQFLKDNNRR-----VDIIEVKLIVWQLFRGQAHLEKS 146
Query: 132 RILHRDLKPQNLLIN-NRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGSRNY 190
I HRD+KPQNLL N + G LK+ D+G + + S V T +YR P++L+GS+NY
Sbjct: 147 EICHRDIKPQNLLYNADTGLLKISDYGSSAIESVKTPQQSYHV-TRYYRPPELLLGSKNY 205
Query: 191 CTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTP-VEQTWPQVTQLAKYNPL 249
ID WSCGC+ E++ G G + + Q +++FD G P E KY +
Sbjct: 206 GCKIDTWSCGCVFGELLKGGIFLAGKSAKNQAEVVFDMFGVPTAEDVSSMNVSNTKYKEI 265
Query: 250 LPPHMP--------------------RDLKQLLQNNTEEVLD-DNVVDLLHGLLQLNPDA 288
+ + P RD + + N + D + V+LL +L NP
Sbjct: 266 IQSYEPDTSKRTADLAYLYNQTASFQRDRRSTVYNTKIDYSDMKDSVELLRQVLVYNPSR 325
Query: 289 RLSAKDALNHPWF 301
RL + L +P+F
Sbjct: 326 RLCGIEFLTNPFF 338
>At3g50000 [TDK] KOG0668 Casein kinase II alpha subunit
Length = 333
Score = 132 bits (333), Expect = 5e-31
Identities = 88/305 (28%), Positives = 165/305 (53%), Gaps = 21/305 (6%)
Query: 11 FKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPSTAIREISLMKEL-KHDNI 69
++ + KVG G Y+ V++G+N +K +K ++ REI +++ L NI
Sbjct: 34 YEVVRKVGRGKYSEVFEGINMNNNEKCIIKILKPVKKKKIR----REIKILQNLCGGPNI 89
Query: 70 VRLFDVIHTENKLT--LVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGVAF 127
V+L DV+ ++ T L+FE++++ K + + L ++Y+ ++LL+ + F
Sbjct: 90 VKLLDVVRDQHSKTPSLIFEYVNSTDFKVL--------YPTLTDYDIRYYIYELLKALDF 141
Query: 128 CHENRILHRDLKPQNLLINNR-GQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMG 186
CH I+HRD+KP N++I++ +L+L D+GLA F P ++ V + +++ P++L+
Sbjct: 142 CHSQGIMHRDVKPHNVMIDHELRKLRLIDWGLAE-FYHPGKEYNVRVASRYFKGPELLVD 200
Query: 187 SRNYCTSIDIWSCGCILAEMIMGK-PLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQL-- 243
++Y S+D+WS GC+ A MI K P F G ++++QL I +GT + QL
Sbjct: 201 LQDYDYSLDMWSLGCMFAGMIFRKEPFFYGHDNQDQLVKIAKVLGTDELNAYLNKYQLEL 260
Query: 244 -AKYNPLLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHPWFA 302
+ L+ H + + + + ++ +D L LL+ + RL+AK+A+ HP+FA
Sbjct: 261 DTQLEALVGRHSRKPWSKFINADNRHLVSPEAIDYLDKLLRYDHQDRLTAKEAMAHPYFA 320
Query: 303 EYNHA 307
+ A
Sbjct: 321 QVRAA 325
>CE27220 [T] KOG0660 Mitogen-activated protein kinase
Length = 472
Score = 131 bits (330), Expect = 1e-30
Identities = 92/321 (28%), Positives = 159/321 (48%), Gaps = 32/321 (9%)
Query: 4 LLRYETRFKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPSTA---IREISL 60
L R ++ + +G+G + V + + ++ VA+K+V S TP+ A +REI +
Sbjct: 75 LERAAETYEPTQNIGSGAFGIVCEAVETSSNQKVAIKKVAHAS--ATPTLARRTLREIRV 132
Query: 61 MKELKHDNIVRLFDVIHTENKLT----LVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKY 116
++ + H NIV L D+ T+ L LV + M N+L + GN LE +
Sbjct: 133 LRYINHPNIVPLRDIFRTKGPLGIDVFLVMDLMQNNLHHII----YGNEDP-LEEHYINA 187
Query: 117 FQWQLLQGVAFCHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSE---- 172
F QLL+G+ + H I HRDLKP NLL+N G L++ DFG+A+ E
Sbjct: 188 FLGQLLRGLEYLHAACIAHRDLKPSNLLVNQDGTLRIADFGMAKCADNSSKKHDDEEHCY 247
Query: 173 -----VVTLWYRAPDVLMGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFD 227
V TL YRAP++L + T++D+W+ GCI EM++ + PG + + Q+K++
Sbjct: 248 YMTQHVATLPYRAPELLFVLPEHSTAVDMWAVGCIFGEMVIRNEILPGRSVQGQIKMLLT 307
Query: 228 TMGTPVEQTWPQVTQLAKYNPLLPPHMPR------DLKQLLQNNTEEVLDDN--VVDLLH 279
+G P ++ +V + + L+ + D+ ++++ N +D +
Sbjct: 308 MLGQPPQEVINEV-RCDRTRKLIQDFGRKADAEWDDIMFCKARGDDQIVRGNCDTIDFVK 366
Query: 280 GLLQLNPDARLSAKDALNHPW 300
L Q + R++ +DAL HP+
Sbjct: 367 QLFQYDAQKRINIQDALLHPY 387
>Hs4503097 [TDK] KOG0668 Casein kinase II alpha subunit
Length = 350
Score = 131 bits (329), Expect = 1e-30
Identities = 85/302 (28%), Positives = 167/302 (55%), Gaps = 27/302 (8%)
Query: 11 FKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPSTAIREISLMKELKHD-NI 69
++ + K+G G Y+ V++ +N T V +K +K ++ RE+ +++ L+ NI
Sbjct: 40 YQLVRKLGRGKYSEVFEAINITNNERVVVKILKPVKKKKIK----REVKILENLRGGTNI 95
Query: 70 VRLFDVIHTENKLT--LVFEFMDN-DLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGVA 126
++L D + T LVFE+++N D K+ ++ L ++++ ++LL+ +
Sbjct: 96 IKLIDTVKDPVSKTPALVFEYINNTDFKQL---------YQILTDFDIRFYMYELLKALD 146
Query: 127 FCHENRILHRDLKPQNLLINN-RGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLM 185
+CH I+HRD+KP N++I++ + +L+L D+GLA F P ++ V + +++ P++L+
Sbjct: 147 YCHSKGIMHRDVKPHNVMIDHQQKKLRLIDWGLAE-FYHPAQEYNVRVASRYFKGPELLV 205
Query: 186 GSRNYCTSIDIWSCGCILAEMIMGK-PLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQL- 243
+ Y S+D+WS GC+LA MI + P F G ++ +QL I +GT E+ + + +
Sbjct: 206 DYQMYDYSLDMWSLGCMLASMIFRREPFFHGQDNYDQLVRIAKVLGT--EELYGYLKKYH 263
Query: 244 ----AKYNPLLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHP 299
+N +L H + + + + ++ +DLL LL+ + RL+AK+A+ HP
Sbjct: 264 IDLDPHFNDILGQHSRKRWENFIHSENRHLVSPEALDLLDKLLRYDHQQRLTAKEAMEHP 323
Query: 300 WF 301
+F
Sbjct: 324 YF 325
>Hs4506095 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 384
Score = 130 bits (327), Expect = 2e-30
Identities = 89/306 (29%), Positives = 152/306 (49%), Gaps = 25/306 (8%)
Query: 10 RFKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPST-AIREISLMKELKHDN 68
R++ L+ +G+G V + VA+K++ + T + A RE+ LMK + H N
Sbjct: 25 RYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKN 84
Query: 69 IVRLFDVIHTENKLT------LVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLL 122
I+ L +V + L +V E MD +L + + L+ + + Y +Q+L
Sbjct: 85 IIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQME--------LDHERMSYLLYQML 136
Query: 123 QGVAFCHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPD 182
G+ H I+HRDLKP N+++ + LK+ DFGLAR G + VVT +YRAP+
Sbjct: 137 CGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSF-MMTPYVVTRYYRAPE 195
Query: 183 VLMGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQ 242
V++G Y ++D+WS GCI+ EM+ K LFPG + +Q + + +GTP + ++
Sbjct: 196 VILG-MGYKENVDLWSVGCIMGEMVCHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKLQP 254
Query: 243 LAK-YNPLLPPHMPRDLKQLL-------QNNTEEVLDDNVVDLLHGLLQLNPDARLSAKD 294
+ Y P + ++L + ++ DLL +L ++ R+S +
Sbjct: 255 TVRTYVENRPKYAGYSFEKLFPDVLFPADSEHNKLKASQARDLLSKMLVIDASKRISVDE 314
Query: 295 ALNHPW 300
AL HP+
Sbjct: 315 ALQHPY 320
>Hs20986523 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 427
Score = 130 bits (327), Expect = 2e-30
Identities = 89/306 (29%), Positives = 152/306 (49%), Gaps = 25/306 (8%)
Query: 10 RFKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPST-AIREISLMKELKHDN 68
R++ L+ +G+G V + VA+K++ + T + A RE+ LMK + H N
Sbjct: 25 RYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKN 84
Query: 69 IVRLFDVIHTENKLT------LVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLL 122
I+ L +V + L +V E MD +L + + L+ + + Y +Q+L
Sbjct: 85 IIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQME--------LDHERMSYLLYQML 136
Query: 123 QGVAFCHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPD 182
G+ H I+HRDLKP N+++ + LK+ DFGLAR G + VVT +YRAP+
Sbjct: 137 CGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSF-MMTPYVVTRYYRAPE 195
Query: 183 VLMGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQ 242
V++G Y ++D+WS GCI+ EM+ K LFPG + +Q + + +GTP + ++
Sbjct: 196 VILG-MGYKENVDLWSVGCIMGEMVCHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKLQP 254
Query: 243 LAK-YNPLLPPHMPRDLKQLL-------QNNTEEVLDDNVVDLLHGLLQLNPDARLSAKD 294
+ Y P + ++L + ++ DLL +L ++ R+S +
Sbjct: 255 TVRTYVENRPKYAGYSFEKLFPDVLFPADSEHNKLKASQARDLLSKMLVIDASKRISVDE 314
Query: 295 ALNHPW 300
AL HP+
Sbjct: 315 ALQHPY 320
>At5g67380 [TDK] KOG0668 Casein kinase II alpha subunit
Length = 333
Score = 130 bits (326), Expect = 3e-30
Identities = 90/308 (29%), Positives = 165/308 (53%), Gaps = 27/308 (8%)
Query: 11 FKQLEKVGNGTYATVYKGLN---KTTGVYVALKEVKLDSEEGTPSTAIREISLMKEL-KH 66
++ + KVG G Y+ V++G+N K + LK VK REI +++ L
Sbjct: 34 YEVVRKVGRGKYSEVFEGINVNSKEKCIIKILKPVKKKKIR-------REIKILQNLCGG 86
Query: 67 DNIVRLFDVIHTENKLT--LVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQG 124
NIV+L DV+ ++ T L+FE++++ K + + L ++Y+ ++LL+
Sbjct: 87 PNIVKLLDVVRDQHSKTPSLIFEYVNSTDFKVL--------YPTLTDYDIRYYIYELLKA 138
Query: 125 VAFCHENRILHRDLKPQNLLINNR-GQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDV 183
+ FCH I+HRD+KP N++I++ +L+L D+GLA F P ++ V + +++ P++
Sbjct: 139 LDFCHSQGIMHRDVKPHNVMIDHELRKLRLIDWGLAE-FYHPGKEYNVRVASRYFKGPEL 197
Query: 184 LMGSRNYCTSIDIWSCGCILAEMIMGK-PLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQ 242
L+ ++Y S+D+WS GC+ A MI K P F G ++++QL I +GT + Q
Sbjct: 198 LVDLQDYDYSLDMWSLGCMFAGMIFRKEPFFYGHDNQDQLVKIAKVLGTDELNAYLNKYQ 257
Query: 243 L---AKYNPLLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHP 299
L + L+ H + + + + + ++ +D L LL+ + RL+AK+A+ H
Sbjct: 258 LELDPQLEALVGRHSRKPWSKFINADNQHLVSPEAIDFLDKLLRYDHQDRLTAKEAMAHA 317
Query: 300 WFAEYNHA 307
+FA+ A
Sbjct: 318 YFAQVRAA 325
>7298142 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 722
Score = 129 bits (325), Expect = 4e-30
Identities = 73/231 (31%), Positives = 135/231 (57%), Gaps = 18/231 (7%)
Query: 10 RFKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPSTAIREISLMKELKHD-- 67
R++ LE +G G++ V + L+ T +VA+K ++ +++ + A+ E++++ EL+
Sbjct: 197 RYEILEVIGKGSFGQVIRALDHKTNTHVAIKIIR--NKKRFLNQAVVELNILDELREKDA 254
Query: 68 ----NIVRLFDVIHTENKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQ 123
N++ + D + L + FE M +L + + K N++ G M L++ F +++
Sbjct: 255 DGSHNVIHMLDYTYFRKHLCITFELMSLNLYELI----KKNNYNGFSMSLIRRFCNSIVK 310
Query: 124 GVAFCHENRILHRDLKPQNLLINNRGQ--LKLGDFGLARAFGIPVNTFSSEVVTLWYRAP 181
+ ++ I+H DLKP+N+L+ RG +K+ DFG + + T+ + + +YR+P
Sbjct: 311 CLRLLYKENIIHCDLKPENILLKQRGSSSIKVIDFGSSCYVDRKIYTY---IQSRFYRSP 367
Query: 182 DVLMGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTP 232
+V++G + Y T+ID+WS GCILAE+ G PLFPG N+ EQL I + +G P
Sbjct: 368 EVILGLQ-YGTAIDMWSLGCILAELYTGFPLFPGENEVEQLACIMEVLGLP 417
>SPAC3C7.06c [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 650
Score = 129 bits (324), Expect = 5e-30
Identities = 92/306 (30%), Positives = 159/306 (51%), Gaps = 28/306 (9%)
Query: 11 FKQLEKVGNGTYATVYKGLNKTTGV-YVALKEVKLDSEEGTPSTAIREI-SLMKELKHDN 68
+ + KVG+GT+ +VY KT VA+K +K + + +T +RE+ SL++ +++N
Sbjct: 36 YNVVRKVGDGTFGSVYLATTKTPSKEVVAIKSMKKKLAKVSDATRLREVHSLLRLSENEN 95
Query: 69 IVRLFDVIHTENK-LTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGVAF 127
IV +FD+ + + L +V EF+D +L + + R + L ++ V+ Q+ +G+
Sbjct: 96 IVNIFDLYIDQFRCLHIVMEFLDCNLYQLISTRK----NDPLTLEQVQDIMRQIFKGLNH 151
Query: 128 CHENRILHRDLKPQNLLINNRGQ-----LKLGDFGLARAFGIPVNTFSSEVVTLWYRAPD 182
H N HRD+KP+N+LI++ +K+ DFGLAR ++ V T WYRAP+
Sbjct: 152 IHTNGFFHRDMKPENILISSNSDSSSFNVKIADFGLAREINSRP-PYTEYVSTRWYRAPE 210
Query: 183 VLMGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQT------ 236
+L+ Y +DI++ GC+ E+ +P+FPG++D +QL + + +G+P EQ+
Sbjct: 211 LLLRDSYYSFPVDIYAAGCMAFEIATLQPIFPGNDDFDQLYKMCEILGSPDEQSQNTGDK 270
Query: 237 ----WPQVTQLA-KYNPLLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLS 291
W + LA K LP P D L +L LL+ +P R +
Sbjct: 271 GGGIWDRAELLANKLGISLPKMAPLDFGDLFSPPWNLAF----ASMLSQLLKWDPAKRPT 326
Query: 292 AKDALN 297
A+ L+
Sbjct: 327 AEMCLD 332
>YIL035c [TDK] KOG0668 Casein kinase II alpha subunit
Length = 372
Score = 128 bits (321), Expect = 1e-29
Identities = 98/350 (28%), Positives = 178/350 (50%), Gaps = 66/350 (18%)
Query: 4 LLRYETRFKQLE---KVGNGTYATVYKGLNKTTGVYVALKEVK----------------L 44
++ + T K E KVG G Y+ V++G+ + V + +K +K L
Sbjct: 30 VIDWSTNTKDYEIENKVGRGKYSEVFQGVKLDSKVKIVIKMLKPVKKKKIKREIKILTDL 89
Query: 45 DSEEGTPST---------AIREISLMKELK----------HDNIVRLFDVIHTENKLT-- 83
+E+ P+T ++ ++K ++ H NI+ LFD+I T
Sbjct: 90 SNEKVPPTTLPFQKDQYYTNQKEDVLKFIRPYIFDQPHNGHANIIHLFDIIKDPISKTPA 149
Query: 84 LVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGVAFCHENRILHRDLKPQNL 143
LVFE++DN +D R LE ++++ ++LL+ + +CH I+HRD+KP N+
Sbjct: 150 LVFEYVDN-----VDFRILYPKLTDLE---IRFYMFELLKALDYCHSMGIMHRDVKPHNV 201
Query: 144 LINNRG-QLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGSRNYCTSIDIWSCGCI 202
+I+++ +L+L D+GLA + + + ++ V + +++ P++L+ R Y S+D+WS G +
Sbjct: 202 MIDHKNKKLRLIDWGLAEFYHVNME-YNVRVASRFFKGPELLVDYRMYDYSLDLWSFGTM 260
Query: 203 LAEMIMGK-PLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQLAKYNPLLPPHMPRDLKQL 261
LA MI + P F G+++ +QL I +GT + + L KY LP D+ Q
Sbjct: 261 LASMIFKREPFFHGTSNTDQLVKIVKVLGTSDFEKY-----LLKYEITLPREF-YDMDQY 314
Query: 262 LQNNTEEVL---------DDNVVDLLHGLLQLNPDARLSAKDALNHPWFA 302
++ + +D ++DL+ LL+ + RL+AK+A+ HPWFA
Sbjct: 315 IRKPWHRFINDGNKHLSGNDEIIDLIDNLLRYDHQERLTAKEAMGHPWFA 364
>Hs4503095 [TDK] KOG0668 Casein kinase II alpha subunit
Length = 391
Score = 127 bits (320), Expect = 2e-29
Identities = 83/302 (27%), Positives = 165/302 (54%), Gaps = 27/302 (8%)
Query: 11 FKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPSTAIREISLMKELKHD-NI 69
++ + K+G G Y+ V++ +N T V +K +K ++ REI +++ L+ NI
Sbjct: 39 YQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIK----REIKILENLRGGPNI 94
Query: 70 VRLFDVIHTENKLT--LVFEFMDN-DLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQGVA 126
+ L D++ T LVFE ++N D K+ + ++++ +++L+ +
Sbjct: 95 ITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYD---------IRFYMYEILKALD 145
Query: 127 FCHENRILHRDLKPQNLLINNRGQ-LKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLM 185
+CH I+HRD+KP N++I++ + L+L D+GLA F P ++ V + +++ P++L+
Sbjct: 146 YCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAE-FYHPGQEYNVRVASRYFKGPELLV 204
Query: 186 GSRNYCTSIDIWSCGCILAEMIMGK-PLFPGSNDEEQLKLIFDTMGTPVEQTWPQVTQL- 243
+ Y S+D+WS GC+LA MI K P F G ++ +QL I +GT E + + +
Sbjct: 205 DYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGT--EDLYDYIDKYN 262
Query: 244 ----AKYNPLLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALNHP 299
++N +L H + ++ + + + ++ +D L LL+ + +RL+A++A+ HP
Sbjct: 263 IELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHP 322
Query: 300 WF 301
+F
Sbjct: 323 YF 324
>Hs5922004 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 601
Score = 127 bits (319), Expect = 2e-29
Identities = 96/324 (29%), Positives = 165/324 (50%), Gaps = 43/324 (13%)
Query: 10 RFKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPSTAIREISLMKELKHDNI 69
R++ L+ +G G++ V K + +VALK V+ +E+ A EI +++ L+ +
Sbjct: 221 RYEVLKVIGKGSFGQVVKAYDHKVHQHVALKMVR--NEKRFHRQAAEEIRILEHLRKQDK 278
Query: 70 VRLFDVIHT------ENKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQ 123
+VIH N + + FE + +L + + K N +G + LV+ F +LQ
Sbjct: 279 DNTMNVIHMLENFTFRNHICMTFELLSMNLYELI----KKNKFQGFSLPLVRKFAHSILQ 334
Query: 124 GVAFCHENRILHRDLKPQNLLINNRGQ--LKLGDFGLARAFGIPVNTFSSEVVTLWYRAP 181
+ H+NRI+H DLKP+N+L+ +G+ +K+ DFG + V T+ + + +YRAP
Sbjct: 335 CLDALHKNRIIHCDLKPENILLKQQGRSGIKVIDFGSSCYEHQRVYTY---IQSRFYRAP 391
Query: 182 DVLMGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQT----- 236
+V++G+R Y ID+WS GCILAE++ G PL PG ++ +QL + + +G P ++
Sbjct: 392 EVILGAR-YGMPIDMWSLGCILAELLTGYPLLPGEDEGDQLACMIELLGMPSQKLLDASK 450
Query: 237 ----------WPQ---VTQLAKYNPLLPPHMPRDLK------QLLQNNTEEVLDDNV-VD 276
+P+ VT L+ + +L R K N + DD + +D
Sbjct: 451 RAKNFVSSKGYPRYCTVTTLSDGSVVLNGGRSRRGKLRGPPESREWGNALKGCDDPLFLD 510
Query: 277 LLHGLLQLNPDARLSAKDALNHPW 300
L L+ +P R++ AL HPW
Sbjct: 511 FLKQCLEWDPAVRMTPGQALRHPW 534
>Hs4503427 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 528
Score = 127 bits (319), Expect = 2e-29
Identities = 96/324 (29%), Positives = 165/324 (50%), Gaps = 43/324 (13%)
Query: 10 RFKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPSTAIREISLMKELKHDNI 69
R++ L+ +G G++ V K + +VALK V+ +E+ A EI +++ L+ +
Sbjct: 148 RYEVLKVIGKGSFGQVVKAYDHKVHQHVALKMVR--NEKRFHRQAAEEIRILEHLRKQDK 205
Query: 70 VRLFDVIHT------ENKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQ 123
+VIH N + + FE + +L + + K N +G + LV+ F +LQ
Sbjct: 206 DNTMNVIHMLENFTFRNHICMTFELLSMNLYELI----KKNKFQGFSLPLVRKFAHSILQ 261
Query: 124 GVAFCHENRILHRDLKPQNLLINNRGQ--LKLGDFGLARAFGIPVNTFSSEVVTLWYRAP 181
+ H+NRI+H DLKP+N+L+ +G+ +K+ DFG + V T+ + + +YRAP
Sbjct: 262 CLDALHKNRIIHCDLKPENILLKQQGRSGIKVIDFGSSCYEHQRVYTY---IQSRFYRAP 318
Query: 182 DVLMGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQT----- 236
+V++G+R Y ID+WS GCILAE++ G PL PG ++ +QL + + +G P ++
Sbjct: 319 EVILGAR-YGMPIDMWSLGCILAELLTGYPLLPGEDEGDQLACMIELLGMPSQKLLDASK 377
Query: 237 ----------WPQ---VTQLAKYNPLLPPHMPRDLK------QLLQNNTEEVLDDNV-VD 276
+P+ VT L+ + +L R K N + DD + +D
Sbjct: 378 RAKNFVSSKGYPRYCTVTTLSDGSVVLNGGRSRRGKLRGPPESREWGNALKGCDDPLFLD 437
Query: 277 LLHGLLQLNPDARLSAKDALNHPW 300
L L+ +P R++ AL HPW
Sbjct: 438 FLKQCLEWDPAVRMTPGQALRHPW 461
>CE23751 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 796
Score = 127 bits (319), Expect = 2e-29
Identities = 90/328 (27%), Positives = 158/328 (47%), Gaps = 51/328 (15%)
Query: 10 RFKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPSTAIREISLMKELKHD-- 67
R++ L+ +G G++ V K + YVALK V+ +E+ A EI ++ L+
Sbjct: 460 RYEVLKVIGKGSFGQVIKAFDHKYQQYVALKLVR--NEKRFHRQADEEIRILDHLRRQDS 517
Query: 68 ----NIVRLFDVIHTENKLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQ 123
NI+ + D + N + FE + +L + + K N +G + LV+ F + +L
Sbjct: 518 DGTHNIIHMLDYFNFRNHKCITFELLSINLYELI----KRNKFQGFSLMLVRKFAYSMLL 573
Query: 124 GVAFCHENRILHRDLKPQNLLINNRGQ--LKLGDFGLARAFGIPVNTFSSEVVTLWYRAP 181
+ +NR++H DLKP+N+L+ +G+ +K+ DFG + + T+ + + +YRAP
Sbjct: 574 CLDLLQKNRLIHCDLKPENVLLKQQGRSGIKVIDFGSSCFDDQRIYTY---IQSRFYRAP 630
Query: 182 DVLMGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTWPQVT 241
+V++G++ Y ID+WS GCILAE++ G PL PG ++ +QL LI + +G P ++
Sbjct: 631 EVILGTK-YGMPIDMWSLGCILAELLTGYPLLPGEDENDQLALIIELLGMPPPKSLETAK 689
Query: 242 QL-----------------------------AKYNPLLPPHMPRDLKQLLQNNTEEVLDD 272
+ +K + P R L+N +E+
Sbjct: 690 RARTFITSKGYPRYCTATSMPDGSVVLAGARSKRGKMRGPPASRSWSTALKNMGDELF-- 747
Query: 273 NVVDLLHGLLQLNPDARLSAKDALNHPW 300
VD L L +P+ R++ AL H W
Sbjct: 748 --VDFLKRCLDWDPETRMTPAQALKHKW 773
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.320 0.138 0.416
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,461,731
Number of Sequences: 60738
Number of extensions: 867959
Number of successful extensions: 7885
Number of sequences better than 10.0: 2067
Number of HSP's better than 10.0 without gapping: 1788
Number of HSP's successfully gapped in prelim test: 279
Number of HSP's that attempted gapping in prelim test: 2234
Number of HSP's gapped (non-prelim): 2604
length of query: 308
length of database: 30,389,216
effective HSP length: 106
effective length of query: 202
effective length of database: 23,950,988
effective search space: 4838099576
effective search space used: 4838099576
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)